AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 SUPERFAMILY SSF47005 261 302 8.63E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 340 565 4.7E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 SUPERFAMILY SSF52777 329 564 4.23E-82 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:3.90.1170.30 65 98 2.8E-5 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:3.90.1170.30 180 228 0.071 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:3.30.559.10 325 566 1.8E-79 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Pfam PF02817 e3 binding domain 263 298 1.7E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:4.10.320.10 255 317 1.8E-17 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 96 566 5.7E-185 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 SUPERFAMILY SSF51230 119 210 3.53E-21 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:2.40.50.100 99 179 4.7E-13 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Gene3D G3DSA:2.40.50.100 7 64 2.4E-13 T 28-03-2018 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 SUPERFAMILY SSF51230 3 95 4.32E-21 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 142 171 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Pfam PF00364 Biotin-requiring enzyme 6 77 7.2E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS10265 3d0428b9fdbe01d2029bd35263c4e68f 566 Pfam PF00364 Biotin-requiring enzyme 120 191 9.2E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS10850 4724ca00bbc79de52c1b60c7650cb744 459 Pfam PF03631 Virulence factor BrkB 55 303 1.3E-55 T 28-03-2018 IPR017039 Virulence factor BrkB AFA_RS10850 4724ca00bbc79de52c1b60c7650cb744 459 Gene3D G3DSA:1.10.10.10 321 405 4.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10850 4724ca00bbc79de52c1b60c7650cb744 459 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 28 332 22.338 T 28-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial AFA_RS10850 4724ca00bbc79de52c1b60c7650cb744 459 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 48 302 2.1E-68 T 28-03-2018 IPR017039 Virulence factor BrkB AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 167 6.7E-6 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 202 4.6E-53 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 Gene3D G3DSA:3.30.930.10 2 212 7.7E-59 T 28-03-2018 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 Hamap MF_00013 Octanoyltransferase [lipB]. 7 214 36.559 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 129 4.0E-15 T 28-03-2018 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 SUPERFAMILY SSF55681 13 211 4.72E-64 T 28-03-2018 AFA_RS01240 bfc85aaa6ba08b724406365440aeb547 220 PIRSF PIRSF016262 1 219 8.3E-57 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 Gene3D G3DSA:1.10.10.10 1 77 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 SUPERFAMILY SSF46785 13 78 1.57E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 Pfam PF07729 FCD domain 100 228 2.2E-24 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 SMART SM00895 100 229 1.0E-22 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 SUPERFAMILY SSF48008 98 236 1.1E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 Gene3D G3DSA:1.20.120.530 81 247 1.4E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 SMART SM00345 16 75 2.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS05485 5335b0beb677e91d6bd271646ae85ab0 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 4.2E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 SUPERFAMILY SSF51621 6 430 2.11E-156 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 Pfam PF00463 Isocitrate lyase family 13 252 9.6E-58 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 Pfam PF00463 Isocitrate lyase family 255 430 1.3E-44 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 PIRSF PIRSF001362 1 433 4.2E-236 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 252 1.3E-109 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFA_RS11780 56074de9942551b080a136ef4dd6c8ed 435 Gene3D G3DSA:3.20.20.60 1 413 3.6E-148 T 28-03-2018 AFA_RS16640 92e0ea8d8c33f45347f7eb5b2413d52c 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 257 2.4E-80 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS16640 92e0ea8d8c33f45347f7eb5b2413d52c 258 Gene3D G3DSA:1.10.12.10 219 256 6.6E-24 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS16640 92e0ea8d8c33f45347f7eb5b2413d52c 258 SUPERFAMILY SSF52096 2 258 2.49E-92 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS16640 92e0ea8d8c33f45347f7eb5b2413d52c 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AFA_RS16640 92e0ea8d8c33f45347f7eb5b2413d52c 258 Gene3D G3DSA:3.90.226.10 1 218 6.4E-76 T 28-03-2018 AFA_RS04555 6730e2ea5f898f0befdb463de9afd685 223 Gene3D G3DSA:1.10.1670.10 166 220 9.1E-14 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFA_RS04555 6730e2ea5f898f0befdb463de9afd685 223 Gene3D G3DSA:1.10.340.30 52 164 1.1E-23 T 28-03-2018 AFA_RS04555 6730e2ea5f898f0befdb463de9afd685 223 SUPERFAMILY SSF48150 44 215 1.88E-40 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFA_RS04555 6730e2ea5f898f0befdb463de9afd685 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 60 188 1.1E-9 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS04555 6730e2ea5f898f0befdb463de9afd685 223 SMART SM00478 64 217 4.0E-14 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 Gene3D G3DSA:3.40.50.720 51 250 4.4E-63 T 28-03-2018 AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 Gene3D G3DSA:3.40.50.10090 1 50 1.7E-11 T 28-03-2018 AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 SUPERFAMILY SSF51735 1 249 4.35E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 4.2E-70 T 28-03-2018 AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13995 aa6341950db9583fe1f553dd3785c385 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07845 c74e228fa7457bf527ee6bde043f25d4 400 Gene3D G3DSA:1.10.150.130 93 206 1.5E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS07845 c74e228fa7457bf527ee6bde043f25d4 400 SUPERFAMILY SSF56349 98 384 2.56E-63 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS07845 c74e228fa7457bf527ee6bde043f25d4 400 Pfam PF00589 Phage integrase family 203 373 1.0E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS07845 c74e228fa7457bf527ee6bde043f25d4 400 Pfam PF13356 Arm DNA-binding domain 2 88 1.1E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain AFA_RS07845 c74e228fa7457bf527ee6bde043f25d4 400 Gene3D G3DSA:1.10.443.10 207 383 4.4E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS16735 c3d8336bd8b9b2b8e7063507b6432da1 346 PIRSF PIRSF038991 1 346 5.4E-80 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 AFA_RS16735 c3d8336bd8b9b2b8e7063507b6432da1 346 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 10 160 8.0E-33 T 28-03-2018 IPR017516 AbrB duplication AFA_RS16735 c3d8336bd8b9b2b8e7063507b6432da1 346 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 183 336 1.8E-35 T 28-03-2018 IPR017516 AbrB duplication AFA_RS16735 c3d8336bd8b9b2b8e7063507b6432da1 346 Pfam PF05145 Transition state regulatory protein AbrB 30 337 3.1E-79 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 310 3.3E-90 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 313 35.198 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 140 163 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 Gene3D G3DSA:3.10.25.10 214 313 1.8E-24 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 Pfam PF00551 Formyl transferase 1 188 6.1E-40 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 Pfam PF02911 Formyl transferase, C-terminal domain 211 309 1.9E-23 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 SUPERFAMILY SSF53328 1 214 7.2E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 SUPERFAMILY SSF50486 212 311 1.08E-25 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 AFA_RS01145 75a8b88feb2e91b86bbf89bafd84cd4a 313 Gene3D G3DSA:3.40.50.170 1 213 2.8E-70 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS03635 e046a9999fec82e49372a843bfa9d1fb 100 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 2 84 4.6E-22 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AFA_RS03635 e046a9999fec82e49372a843bfa9d1fb 100 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 15.061 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AFA_RS03635 e046a9999fec82e49372a843bfa9d1fb 100 Pfam PF04999 Cell division protein FtsL 3 84 9.6E-16 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AFA_RS02290 5ca7c5e8e7c8b37568d130716df3830f 60 SUPERFAMILY SSF56935 4 60 5.19E-13 T 28-03-2018 AFA_RS02290 5ca7c5e8e7c8b37568d130716df3830f 60 Gene3D G3DSA:2.40.170.20 2 60 9.4E-13 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS02290 5ca7c5e8e7c8b37568d130716df3830f 60 Pfam PF00593 TonB dependent receptor 4 59 1.1E-9 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS02290 5ca7c5e8e7c8b37568d130716df3830f 60 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 43 60 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 Gene3D G3DSA:2.102.10.10 48 163 1.2E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 199 221 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 70 85 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 112 132 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 160 186 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 39 64 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 91 111 5.4E-28 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 98 121 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 Gene3D G3DSA:3.90.380.10 164 429 4.3E-54 T 28-03-2018 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 Pfam PF00355 Rieske [2Fe-2S] domain 55 139 8.7E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 207 428 2.6E-18 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 SUPERFAMILY SSF50022 28 175 8.12E-44 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS15110 3bc2eecaad39b2f402ddfb89035f622f 429 SUPERFAMILY SSF55961 178 428 7.06E-42 T 28-03-2018 AFA_RS13640 e89a79536eb494469945033eca8416af 467 SUPERFAMILY SSF52540 139 368 4.8E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13640 e89a79536eb494469945033eca8416af 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 163 176 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS13640 e89a79536eb494469945033eca8416af 467 SMART SM00382 159 306 2.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13640 e89a79536eb494469945033eca8416af 467 Gene3D G3DSA:3.40.50.300 135 311 8.3E-24 T 28-03-2018 AFA_RS13640 e89a79536eb494469945033eca8416af 467 Pfam PF00158 Sigma-54 interaction domain 140 305 3.8E-65 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS13640 e89a79536eb494469945033eca8416af 467 Gene3D G3DSA:1.10.8.60 315 376 1.3E-7 T 28-03-2018 AFA_RS13640 e89a79536eb494469945033eca8416af 467 Gene3D G3DSA:1.10.10.60 377 460 8.1E-9 T 28-03-2018 AFA_RS13640 e89a79536eb494469945033eca8416af 467 Pfam PF02954 Bacterial regulatory protein, Fis family 417 456 1.9E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS13640 e89a79536eb494469945033eca8416af 467 SUPERFAMILY SSF46689 407 458 9.41E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 5.8E-18 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 PIRSF PIRSF005901 1 185 7.3E-57 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 SMART SM00841 128 183 2.9E-29 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Gene3D G3DSA:2.40.50.140 128 183 7.5E-26 T 28-03-2018 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 SUPERFAMILY SSF50104 1 63 4.06E-16 T 28-03-2018 IPR008991 Translation protein SH3-like domain AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 SUPERFAMILY SSF50249 65 126 1.5E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 1.4E-65 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 SMART SM01185 67 120 6.7E-21 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Pfam PF09285 Elongation factor P, C-terminal 128 183 2.0E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 SUPERFAMILY SSF50249 128 184 1.37E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.4E-18 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Hamap MF_00141 Elongation factor P [efp]. 1 184 47.541 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Gene3D G3DSA:2.30.30.30 2 61 1.3E-17 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 AFA_RS04765 dbc26edafc2426761d7638c63a5504c3 185 Gene3D G3DSA:2.40.50.140 65 125 5.3E-21 T 28-03-2018 AFA_RS03510 3757dd40f8c33244aaa0844b60e568db 216 Gene3D G3DSA:3.20.10.10 83 214 1.9E-24 T 28-03-2018 AFA_RS03510 3757dd40f8c33244aaa0844b60e568db 216 Pfam PF01063 Amino-transferase class IV 8 207 2.0E-33 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS03510 3757dd40f8c33244aaa0844b60e568db 216 Gene3D G3DSA:3.30.470.10 7 82 4.4E-15 T 28-03-2018 AFA_RS03510 3757dd40f8c33244aaa0844b60e568db 216 SUPERFAMILY SSF56752 7 208 4.97E-39 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS10390 99d0d067b684883e8469ebd0acfa473f 245 SUPERFAMILY SSF63892 1 237 7.06E-96 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFA_RS10390 99d0d067b684883e8469ebd0acfa473f 245 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 237 1.5E-93 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFA_RS10390 99d0d067b684883e8469ebd0acfa473f 245 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 235 2.6E-100 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFA_RS10390 99d0d067b684883e8469ebd0acfa473f 245 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 241 126.95 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFA_RS10390 99d0d067b684883e8469ebd0acfa473f 245 Gene3D G3DSA:3.20.20.70 2 236 2.9E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 190 1.7E-47 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 SUPERFAMILY SSF52540 8 192 2.17E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 Gene3D G3DSA:3.30.1220.10 217 347 1.2E-16 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 Gene3D G3DSA:3.40.50.300 6 208 4.3E-35 T 28-03-2018 AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 SUPERFAMILY SSF90002 252 342 1.57E-14 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 253 342 1.5E-12 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS00200 6bf9be84eefb5f87b1fe3599cafd2399 352 SMART SM00833 252 346 1.4E-6 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS06295 062be958f753dba56b2461a47b70a208 558 Pfam PF01170 Putative RNA methylase family UPF0020 53 180 7.2E-5 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 SUPERFAMILY SSF53335 48 276 6.78E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06295 062be958f753dba56b2461a47b70a208 558 Gene3D G3DSA:3.90.220.10 325 487 7.2E-9 T 28-03-2018 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 TIGRFAM TIGR02987 met_A_Alw26: type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family 31 547 1.1E-110 T 28-03-2018 IPR014329 M6 adenine DNA methyltransferase, Alw26I AFA_RS06295 062be958f753dba56b2461a47b70a208 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 140 152 1.7E-7 T 28-03-2018 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 32 48 1.7E-7 T 28-03-2018 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 200 224 1.7E-7 T 28-03-2018 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 60 74 1.7E-7 T 28-03-2018 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 143 149 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS06295 062be958f753dba56b2461a47b70a208 558 Gene3D G3DSA:3.40.50.150 26 302 2.2E-25 T 28-03-2018 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 SUPERFAMILY SSF54843 1 107 1.27E-37 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 Pfam PF00237 Ribosomal protein L22p/L17e 7 107 1.9E-33 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 3.3E-43 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 Gene3D G3DSA:3.90.470.10 1 109 6.8E-38 T 28-03-2018 AFA_RS18245 7cced60a0300f2ec1be1ae2585dbca55 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.022 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 Gene3D G3DSA:1.10.260.40 2 74 1.2E-16 T 28-03-2018 AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 SUPERFAMILY SSF51182 45 175 1.69E-26 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 Pfam PF01381 Helix-turn-helix 6 57 6.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 Pfam PF07883 Cupin domain 104 169 5.4E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 SMART SM00530 5 60 3.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 SUPERFAMILY SSF47413 4 64 1.15E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS06605 787b113dddf090eb12d295b89bcd9df3 176 Gene3D G3DSA:2.60.120.10 75 176 2.6E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 SUPERFAMILY SSF51735 4 248 3.66E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 Gene3D G3DSA:3.40.50.10090 1 46 2.0E-11 T 28-03-2018 AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 207 0.0044 T 28-03-2018 AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 1.2E-65 T 28-03-2018 AFA_RS10345 abfbaa6baaa804250618af736fd538b3 251 Gene3D G3DSA:3.40.50.720 47 251 1.7E-61 T 28-03-2018 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 SUPERFAMILY SSF56935 25 745 8.24E-138 T 28-03-2018 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 Gene3D G3DSA:2.170.130.10 17 167 4.5E-34 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 Pfam PF00593 TonB dependent receptor 249 742 2.9E-60 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 44 745 1.1E-93 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 Gene3D G3DSA:2.40.170.20 168 745 2.0E-88 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS09195 63aaca3dd5b9cc9dea170a173fcc9847 745 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 156 1.9E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 SUPERFAMILY SSF46785 23 159 2.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 SMART SM00347 45 146 1.7E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 Pfam PF01047 MarR family 52 110 3.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14320 b26655b32501751a65060cd2c0fb1168 185 Gene3D G3DSA:1.10.10.10 9 156 4.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 466 591 2.0E-38 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 1.8E-273 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 SUPERFAMILY SSF56425 241 358 5.38E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 SUPERFAMILY SSF46977 457 592 3.53E-44 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Gene3D G3DSA:3.50.50.60 305 432 2.7E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Gene3D G3DSA:3.50.50.60 2 292 7.6E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Gene3D G3DSA:1.20.58.100 435 544 3.1E-31 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 6.6E-7 T 28-03-2018 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 398 6.6E-7 T 28-03-2018 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 6.6E-7 T 28-03-2018 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 PIRSF PIRSF000171 4 582 1.2E-39 T 28-03-2018 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Gene3D G3DSA:4.10.80.40 545 592 8.5E-18 T 28-03-2018 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 1.6E-237 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 Pfam PF00890 FAD binding domain 14 408 5.5E-118 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 SUPERFAMILY SSF51905 9 264 3.89E-80 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04855 04c0ebd39e07de8dadba7cf9398e0df6 592 SUPERFAMILY SSF51905 362 436 3.89E-80 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00920 a8b08d4b7c78b23987fe4b3e3a9848ec 265 SMART SM00382 34 223 8.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00920 a8b08d4b7c78b23987fe4b3e3a9848ec 265 Gene3D G3DSA:3.40.50.300 6 265 7.8E-60 T 28-03-2018 AFA_RS00920 a8b08d4b7c78b23987fe4b3e3a9848ec 265 SUPERFAMILY SSF52540 8 234 1.25E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00920 a8b08d4b7c78b23987fe4b3e3a9848ec 265 Pfam PF00005 ABC transporter 27 175 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00920 a8b08d4b7c78b23987fe4b3e3a9848ec 265 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS14035 e40b264a93458113004db4a8088deeaf 501 SUPERFAMILY SSF56954 17 481 1.7E-110 T 28-03-2018 AFA_RS14035 e40b264a93458113004db4a8088deeaf 501 Pfam PF02321 Outer membrane efflux protein 78 268 2.3E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS14035 e40b264a93458113004db4a8088deeaf 501 Pfam PF02321 Outer membrane efflux protein 301 476 1.4E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS14035 e40b264a93458113004db4a8088deeaf 501 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 25 478 5.5E-118 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS14035 e40b264a93458113004db4a8088deeaf 501 Gene3D G3DSA:1.20.1600.10 33 484 7.2E-98 T 28-03-2018 AFA_RS06210 36fa333656179dc8024a42150d873993 453 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 2 147 9.4E-58 T 28-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal AFA_RS06460 7db3d076b6956019589a9a68a90c0127 201 SUPERFAMILY SSF56784 2 189 3.63E-23 T 28-03-2018 IPR023214 HAD-like domain AFA_RS06460 7db3d076b6956019589a9a68a90c0127 201 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 2 195 5.0E-36 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like AFA_RS06460 7db3d076b6956019589a9a68a90c0127 201 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 2 184 1.6E-24 T 28-03-2018 AFA_RS06460 7db3d076b6956019589a9a68a90c0127 201 Gene3D G3DSA:3.40.50.1000 1 197 2.8E-12 T 28-03-2018 IPR023214 HAD-like domain AFA_RS06460 7db3d076b6956019589a9a68a90c0127 201 Pfam PF12710 haloacid dehalogenase-like hydrolase 3 183 6.8E-34 T 28-03-2018 AFA_RS00055 4153956bc7c967504919c3e354636d54 145 Gene3D G3DSA:3.90.1590.10 1 142 3.2E-21 T 28-03-2018 AFA_RS00055 4153956bc7c967504919c3e354636d54 145 SUPERFAMILY SSF51316 2 128 6.38E-29 T 28-03-2018 IPR011057 Mss4-like AFA_RS00055 4153956bc7c967504919c3e354636d54 145 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 26 104 2.4E-10 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Pfam PF03448 MgtE intracellular N domain 78 179 8.3E-23 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 TIGRFAM TIGR00400 mgtE: magnesium transporter 61 492 1.2E-84 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SUPERFAMILY SSF161093 321 492 3.01E-41 T 28-03-2018 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Pfam PF01769 Divalent cation transporter 364 485 8.8E-20 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SUPERFAMILY SSF158791 53 178 3.14E-25 T 28-03-2018 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Gene3D G3DSA:1.25.60.10 44 163 1.1E-19 T 28-03-2018 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Gene3D G3DSA:3.10.580.10 164 226 6.4E-4 T 28-03-2018 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Pfam PF00571 CBS domain 245 300 2.9E-5 T 28-03-2018 IPR000644 CBS domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Pfam PF00571 CBS domain 181 237 1.5E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SMART SM00924 78 181 1.8E-32 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Gene3D G3DSA:1.10.357.20 320 493 2.0E-31 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SUPERFAMILY SSF54631 180 315 2.07E-26 T 28-03-2018 AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SMART SM00116 252 300 0.038 T 28-03-2018 IPR000644 CBS domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 SMART SM00116 188 241 0.2 T 28-03-2018 IPR000644 CBS domain AFA_RS03720 78092a357303d6f224d23ca27a879bac 493 Gene3D G3DSA:3.10.580.10 227 309 8.6E-13 T 28-03-2018 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 PIRSF PIRSF004491 5 321 1.2E-94 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 Gene3D G3DSA:3.40.50.620 5 188 3.8E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 SUPERFAMILY SSF52374 19 187 1.69E-29 T 28-03-2018 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 Pfam PF01687 Riboflavin kinase 193 316 1.7E-31 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 SMART SM00904 192 317 1.7E-46 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 Pfam PF06574 FAD synthetase 16 175 3.1E-50 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 22 316 8.6E-85 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 Gene3D G3DSA:2.40.30.30 189 321 2.1E-33 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFA_RS07515 e9e4e3a7ffa2157050f5511a95f6a11c 321 SUPERFAMILY SSF82114 184 317 4.8E-36 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 191 9.3E-93 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 Gene3D G3DSA:1.10.1740.10 1 139 1.2E-31 T 28-03-2018 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 5.9E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 SUPERFAMILY SSF88659 124 187 1.55E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 Pfam PF08281 Sigma-70, region 4 134 182 3.9E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 Gene3D G3DSA:1.10.10.10 140 198 5.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 SUPERFAMILY SSF88946 2 104 2.35E-32 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13090 a9c42cbc229d28dcaad5ec736a60df17 200 Pfam PF04542 Sigma-70 region 2 25 91 2.6E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 SMART SM00436 125 220 3.5E-20 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Gene3D G3DSA:3.40.50.140 3 153 2.4E-32 T 28-03-2018 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 SUPERFAMILY SSF56712 3 613 2.62E-168 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Pfam PF01131 DNA topoisomerase 154 598 1.6E-114 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 SMART SM00437 278 560 2.8E-74 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 SMART SM00493 3 125 3.3E-13 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 330 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Gene3D G3DSA:1.10.460.10 487 620 1.1E-21 T 28-03-2018 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Gene3D G3DSA:1.10.460.10 158 356 1.7E-38 T 28-03-2018 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Pfam PF13342 C-terminal repeat of topoisomerase 754 814 2.9E-18 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Pfam PF13342 C-terminal repeat of topoisomerase 650 708 1.1E-19 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Pfam PF01751 Toprim domain 4 130 6.4E-11 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 618 7.7E-166 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 7.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 7.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 7.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 7.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 7.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFA_RS00645 3211b158b31baa0ab73201ad7b8ae2aa 868 Gene3D G3DSA:2.70.20.10 371 486 2.9E-25 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFA_RS12540 d305184c84ce0091d003365b99749031 203 SUPERFAMILY SSF47616 69 201 1.38E-26 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS12540 d305184c84ce0091d003365b99749031 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 7.5E-18 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS12540 d305184c84ce0091d003365b99749031 203 SUPERFAMILY SSF52833 1 100 6.47E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12540 d305184c84ce0091d003365b99749031 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 184 3.1E-11 T 28-03-2018 AFA_RS12540 d305184c84ce0091d003365b99749031 203 Gene3D G3DSA:1.20.1050.10 93 203 4.9E-24 T 28-03-2018 AFA_RS12540 d305184c84ce0091d003365b99749031 203 Gene3D G3DSA:3.40.30.10 1 92 3.7E-23 T 28-03-2018 AFA_RS09460 cce6196169ff682d80d8801a91a1b012 262 Gene3D G3DSA:3.40.50.150 5 248 1.8E-22 T 28-03-2018 AFA_RS09460 cce6196169ff682d80d8801a91a1b012 262 Pfam PF08241 Methyltransferase domain 65 159 9.4E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AFA_RS09460 cce6196169ff682d80d8801a91a1b012 262 SUPERFAMILY SSF53335 205 261 5.63E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS09460 cce6196169ff682d80d8801a91a1b012 262 SUPERFAMILY SSF53335 41 168 5.63E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF53335 1335 1521 3.38E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF53901 395 417 5.36E-94 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF53901 1 363 5.36E-94 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00823 Phosphopantetheine attachment site 2368 2439 1.5E-14 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF14765 Polyketide synthase dehydratase 888 1156 3.1E-57 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.47.10 258 419 2.0E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF47336 2367 2444 2.62E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF52151 522 650 7.06E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF52151 716 815 7.06E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.50.720 1884 2003 1.4E-23 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00826 888 1045 4.0E-45 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 367 3.1E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF00107 Zinc-binding dehydrogenase 1893 1990 1.4E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF51735 2084 2272 8.17E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.47.10 1 255 9.3E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00829 1749 2064 7.2E-175 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF13489 Methyltransferase domain 1345 1518 1.4E-9 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.50.720 2081 2342 6.4E-49 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF51735 1853 2008 5.06E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 525 826 3.8E-93 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF50129 1746 1887 1.73E-29 T 28-03-2018 IPR011032 GroES-like AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.90.180.10 1734 1883 8.1E-39 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM01294 2369 2435 6.2E-4 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF08659 KR domain 2088 2266 3.0E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 243 7.8E-77 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.10.129.10 887 1010 5.0E-14 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:1.10.1200.10 2364 2470 1.3E-17 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF51735 1551 1727 1.26E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1882 1903 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SUPERFAMILY SSF55048 648 714 1.57E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.50.150 1177 1533 1.1E-17 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.40.366.10 512 827 1.9E-76 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF00698 Acyl transferase domain 524 819 5.3E-62 T 28-03-2018 IPR014043 Acyl transferase AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 370 472 3.7E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2088 2268 9.0E-50 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 SMART SM00825 Beta-ketoacyl synthase 1 421 6.5E-187 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Gene3D G3DSA:3.90.180.10 2006 2068 2.9E-5 T 28-03-2018 AFA_RS17040 dff8b66167d6ca033c089bf8113e03cd 2491 Pfam PF00550 Phosphopantetheine attachment site 2369 2435 6.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS05695 4c32c4ab3662265895d76e6470493168 369 Pfam PF03781 Sulfatase-modifying factor enzyme 1 64 363 2.1E-79 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFA_RS05695 4c32c4ab3662265895d76e6470493168 369 Gene3D G3DSA:3.90.1580.10 55 369 2.7E-85 T 28-03-2018 AFA_RS05695 4c32c4ab3662265895d76e6470493168 369 SUPERFAMILY SSF56436 65 364 9.23E-85 T 28-03-2018 IPR016187 C-type lectin fold AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 120 6.7E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Gene3D G3DSA:2.40.110.10 123 219 3.7E-25 T 28-03-2018 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.0E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 SUPERFAMILY SSF47203 231 382 1.1E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Gene3D G3DSA:1.10.540.10 2 122 2.2E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 5.9E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 SUPERFAMILY SSF56645 11 241 5.37E-45 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS08185 70c85239044da62a3e1aedccfe0f2a41 397 Gene3D G3DSA:1.20.140.10 220 393 1.2E-36 T 28-03-2018 AFA_RS00975 56439698e194441cf9a1d8b5e91fe273 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 314 4.3E-67 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00975 56439698e194441cf9a1d8b5e91fe273 318 Gene3D G3DSA:3.40.190.10 120 304 2.0E-11 T 28-03-2018 AFA_RS00975 56439698e194441cf9a1d8b5e91fe273 318 PIRSF PIRSF017082 1 317 4.5E-60 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00975 56439698e194441cf9a1d8b5e91fe273 318 SUPERFAMILY SSF53850 114 276 1.17E-9 T 28-03-2018 AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 Gene3D G3DSA:3.40.50.720 5 262 1.6E-48 T 28-03-2018 AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 SUPERFAMILY SSF51735 12 260 4.18E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.1E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16020 389a844fd012b09b7ad5dee717eb705d 263 Pfam PF00106 short chain dehydrogenase 18 204 6.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12325 7fa75f78b41cc205af3b184a3fa15cc6 236 Gene3D G3DSA:3.40.50.300 1 235 2.0E-59 T 28-03-2018 AFA_RS12325 7fa75f78b41cc205af3b184a3fa15cc6 236 SUPERFAMILY SSF52540 6 229 1.4E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12325 7fa75f78b41cc205af3b184a3fa15cc6 236 Pfam PF00005 ABC transporter 25 176 7.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS12325 7fa75f78b41cc205af3b184a3fa15cc6 236 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS12325 7fa75f78b41cc205af3b184a3fa15cc6 236 SMART SM00382 34 231 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 Pfam PF12802 MarR family 29 88 2.6E-13 T 28-03-2018 AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 5.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 5.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 5.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 Gene3D G3DSA:1.10.10.10 1 107 5.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 SMART SM00347 24 125 2.2E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 SUPERFAMILY SSF46785 8 141 1.37E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12890 d6dc9db56aa5d6fecb27dec8ac9aae75 148 Gene3D G3DSA:1.10.287.100 108 133 6.0E-5 T 28-03-2018 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 SUPERFAMILY SSF161098 297 549 2.62E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 SUPERFAMILY SSF161098 5 276 4.84E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 Gene3D G3DSA:1.10.3720.10 8 282 1.1E-36 T 28-03-2018 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 Gene3D G3DSA:1.10.3720.10 300 560 3.0E-32 T 28-03-2018 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 373 550 2.6E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14570 b9a01af783ef83d27f78916659ae0313 561 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 275 1.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16725 f524948d6838aa6574823b082451116a 182 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 43 181 1.9E-30 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFA_RS16725 f524948d6838aa6574823b082451116a 182 Gene3D G3DSA:2.60.40.200 33 182 1.0E-36 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFA_RS16725 f524948d6838aa6574823b082451116a 182 SUPERFAMILY SSF49329 32 182 1.96E-46 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 31 104 6.9E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 PRINTS PR00607 Class IE cytochrome C signature 51 61 2.2E-12 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 PRINTS PR00607 Class IE cytochrome C signature 79 91 2.2E-12 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 PRINTS PR00607 Class IE cytochrome C signature 40 51 2.2E-12 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 PRINTS PR00607 Class IE cytochrome C signature 94 105 2.2E-12 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 SUPERFAMILY SSF46626 14 105 7.34E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS15920 1a0656811625bf3c509d5d988319001e 109 Gene3D G3DSA:1.10.760.10 28 108 1.6E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01850 7e7af4ef9afcc4668f5ddfb18d1e6fd0 244 Pfam PF04172 LrgB-like family 23 234 3.1E-73 T 28-03-2018 IPR007300 CidB/LrgB family AFA_RS01325 6867b86eb43c0d38cee27e608bb45ff8 249 Pfam PF04055 Radical SAM superfamily 39 171 1.8E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS01325 6867b86eb43c0d38cee27e608bb45ff8 249 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 21 208 3.9E-56 T 28-03-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein AFA_RS01325 6867b86eb43c0d38cee27e608bb45ff8 249 Pfam PF13353 4Fe-4S single cluster domain 36 118 4.6E-9 T 28-03-2018 AFA_RS01325 6867b86eb43c0d38cee27e608bb45ff8 249 Gene3D G3DSA:3.20.20.70 33 249 1.9E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01325 6867b86eb43c0d38cee27e608bb45ff8 249 SUPERFAMILY SSF102114 32 219 1.96E-20 T 28-03-2018 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 Pfam PF00082 Subtilase family 62 354 1.8E-47 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 SMART SM00869 644 913 9.0E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 62 81 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 306 322 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 455 921 4.4E-36 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 SUPERFAMILY SSF52743 44 368 4.06E-66 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 Pfam PF12951 Passenger-associated-transport-repeat 393 422 2.0E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 392 423 1.7E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 Gene3D G3DSA:2.40.128.130 599 922 2.4E-52 T 28-03-2018 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 307 317 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 Pfam PF03797 Autotransporter beta-domain 647 903 9.4E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 Gene3D G3DSA:3.40.50.200 30 372 1.2E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16275 84902741ff9662f54cbf76d11039962d 922 SUPERFAMILY SSF103515 609 922 5.23E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 Gene3D G3DSA:2.170.130.10 6 124 6.2E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 Pfam PF00593 TonB dependent receptor 222 670 4.9E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 SUPERFAMILY SSF56935 8 671 1.26E-129 T 28-03-2018 AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 Pfam PF07715 TonB-dependent Receptor Plug Domain 16 117 9.5E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 Gene3D G3DSA:2.40.170.20 130 671 1.0E-79 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS12985 02fcff7a529606136d4cdd85ee46031e 671 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 17 670 8.0E-111 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 106 352 7.9E-11 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 Gene3D G3DSA:3.90.1380.10 1 89 9.7E-31 T 28-03-2018 IPR029144 Threonine synthase, N-terminal AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 Gene3D G3DSA:3.40.50.1100 107 205 4.9E-13 T 28-03-2018 AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 Gene3D G3DSA:3.40.50.1100 206 434 1.9E-84 T 28-03-2018 AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 Pfam PF14821 Threonine synthase N terminus 2 79 5.0E-28 T 28-03-2018 IPR029144 Threonine synthase, N-terminal AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 SUPERFAMILY SSF53686 1 466 4.89E-153 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS05255 f7764cebb987c9cbf78a5d8be80eead5 469 TIGRFAM TIGR00260 thrC: threonine synthase 98 430 3.0E-74 T 28-03-2018 IPR004450 Threonine synthase-like AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Gene3D G3DSA:3.30.499.10 372 600 2.7E-68 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Pfam PF00694 Aconitase C-terminal domain 715 845 5.5E-41 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 ProSitePatterns PS00450 Aconitase family signature 1. 451 467 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 914 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Pfam PF00330 Aconitase family (aconitate hydratase) 69 586 5.5E-182 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Gene3D G3DSA:3.20.19.10 677 916 5.2E-88 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Gene3D G3DSA:3.30.499.10 42 239 2.5E-74 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 293 306 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 372 386 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 217 232 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 146 159 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 170 178 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 203 216 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 517 530 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 455 466 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 PRINTS PR00415 Aconitase family signature 279 292 1.9E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 ProSitePatterns PS01244 Aconitase family signature 2. 517 530 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 Gene3D G3DSA:3.40.1060.10 240 371 1.3E-45 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 SUPERFAMILY SSF53732 437 651 7.06E-226 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 SUPERFAMILY SSF53732 4 406 7.06E-226 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS17365 902db206541221bbac4c589651cd4b76 917 SUPERFAMILY SSF52016 656 915 5.89E-81 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS15550 918f9be4a914eaa7489fe6692bd78dc2 184 Gene3D G3DSA:1.10.60.30 27 98 8.6E-26 T 28-03-2018 AFA_RS15550 918f9be4a914eaa7489fe6692bd78dc2 184 PIRSF PIRSF016183 2 183 1.8E-58 T 28-03-2018 IPR006839 Ribosome-associated, YjgA AFA_RS15550 918f9be4a914eaa7489fe6692bd78dc2 184 SUPERFAMILY SSF158710 25 178 2.35E-43 T 28-03-2018 IPR023153 PSPTO4464-like domain AFA_RS15550 918f9be4a914eaa7489fe6692bd78dc2 184 Gene3D G3DSA:1.10.60.30 103 184 1.2E-21 T 28-03-2018 AFA_RS15550 918f9be4a914eaa7489fe6692bd78dc2 184 Pfam PF04751 Protein of unknown function (DUF615) 15 175 4.9E-52 T 28-03-2018 IPR006839 Ribosome-associated, YjgA AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 Gene3D G3DSA:3.40.50.720 174 343 1.7E-39 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 Gene3D G3DSA:3.30.390.30 344 473 2.4E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 2.0E-43 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 2.0E-43 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 2.0E-43 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-43 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.0E-43 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 6.2E-162 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 SUPERFAMILY SSF55424 352 473 6.01E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 465 6.6E-36 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 8.1E-77 T 28-03-2018 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 Gene3D G3DSA:3.50.50.60 1 173 3.5E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 SUPERFAMILY SSF51905 2 347 6.4E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 4.5E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04900 9fd6b1550d8d87c4afc22903697570de 475 PIRSF PIRSF000350 1 474 2.7E-84 T 28-03-2018 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 Pfam PF03466 LysR substrate binding domain 88 289 3.7E-34 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 SUPERFAMILY SSF53850 89 295 2.17E-35 T 28-03-2018 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 Gene3D G3DSA:1.10.10.10 1 86 2.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 Gene3D G3DSA:3.40.190.10 88 174 2.6E-15 T 28-03-2018 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 Gene3D G3DSA:3.40.190.10 175 264 6.7E-14 T 28-03-2018 AFA_RS01185 045a0cefaa91bf177014dc6ed10eb3cd 299 SUPERFAMILY SSF46785 1 111 1.82E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 Pfam PF07729 FCD domain 75 204 1.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 SMART SM00895 75 205 8.5E-16 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 SUPERFAMILY SSF48008 71 213 2.59E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 54 4.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 Gene3D G3DSA:1.10.10.10 1 67 3.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 SUPERFAMILY SSF46785 5 69 3.01E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 SMART SM00345 7 65 3.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02110 aebb2fabd4a324c22f679cd4f48a359e 217 Gene3D G3DSA:1.20.120.530 68 217 4.9E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 403 576 2.48E-14 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF13018 Extended Signal Peptide of Type V secretion system 34 55 5.0E-8 T 28-03-2018 IPR024973 ESPR domain AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2335 2375 5.7E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2854 2874 8.0E-9 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1889 1929 4.2E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2558 2598 4.2E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1220 1260 4.2E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 2112 2152 4.2E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 952 995 6.9E-11 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 552 579 5.5E-9 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 3022 3059 6.7E-12 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1443 1483 5.7E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1666 1706 4.2E-10 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 386 577 1.6E-21 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 249 385 9.0E-20 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 2152 2360 2.5E-8 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 2883 3040 1.9E-8 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 1260 1468 2.5E-8 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 2732 2878 3.5E-12 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF03895 YadA-like membrane anchor domain 3079 3139 2.1E-19 T 28-03-2018 IPR005594 YadA-like, C-terminal AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 2543 2582 8.89E-5 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 2442 2514 8.89E-5 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 2923 3043 2.48E-6 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 723 805 3.53E-8 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.90.1780.10 1801 1941 2.5E-7 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.90.1780.10 1578 1718 2.8E-7 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.90.1780.10 2024 2151 2.5E-7 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.90.1780.10 2470 2610 2.8E-7 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.90.1780.10 1132 1259 2.5E-7 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 1651 1690 8.89E-5 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 1550 1622 8.89E-5 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 258 400 2.62E-13 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:1.20.5.730 152 237 1.9E-8 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05658 Head domain of trimeric autotransporter adhesin 260 286 5.4E-6 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Pfam PF05658 Head domain of trimeric autotransporter adhesin 337 363 1.8E-5 T 28-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:3.30.1300.30 3041 3139 2.2E-25 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 809 986 1.0E-32 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 599 719 3.4E-13 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.150.10.10 720 808 1.5E-9 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 624 718 1.05E-10 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF101967 816 977 1.31E-28 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.160.30.10 2443 2469 0.0024 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.160.30.10 1774 1800 0.0024 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.160.30.10 1105 1131 0.0024 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.160.30.10 1551 1577 0.0024 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 Gene3D G3DSA:2.160.30.10 1997 2023 0.0024 T 28-03-2018 AFA_RS14225 c1087ed9b3ad4cb4cd209e9fd4dbb363 3139 SUPERFAMILY SSF54523 3032 3139 1.73E-26 T 28-03-2018 AFA_RS00515 e7090916e8366671a0e57d7b0a0dbbad 477 Gene3D G3DSA:3.20.20.30 4 458 3.5E-108 T 28-03-2018 AFA_RS00515 e7090916e8366671a0e57d7b0a0dbbad 477 Pfam PF00296 Luciferase-like monooxygenase 27 387 1.1E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS00515 e7090916e8366671a0e57d7b0a0dbbad 477 PIRSF PIRSF000337 5 448 7.2E-129 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS00515 e7090916e8366671a0e57d7b0a0dbbad 477 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 433 3.1E-153 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS00515 e7090916e8366671a0e57d7b0a0dbbad 477 SUPERFAMILY SSF51679 5 438 4.32E-118 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS05725 5a7b66a5cf5372a41178dd5885ba5540 108 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 12 99 9.0E-27 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 AFA_RS05725 5a7b66a5cf5372a41178dd5885ba5540 108 SUPERFAMILY SSF63592 4 99 7.19E-31 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 AFA_RS05725 5a7b66a5cf5372a41178dd5885ba5540 108 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 3 106 24.215 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 AFA_RS05725 5a7b66a5cf5372a41178dd5885ba5540 108 Pfam PF05247 Flagellar transcriptional activator (FlhD) 5 102 1.8E-36 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 AFA_RS05725 5a7b66a5cf5372a41178dd5885ba5540 108 Gene3D G3DSA:1.10.4000.10 5 104 5.5E-33 T 28-03-2018 AFA_RS10000 a8c71f354d4bd44799fe840301c27040 374 Gene3D G3DSA:1.10.443.10 139 344 2.3E-14 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS10000 a8c71f354d4bd44799fe840301c27040 374 Gene3D G3DSA:1.10.150.130 19 138 2.1E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS10000 a8c71f354d4bd44799fe840301c27040 374 SUPERFAMILY SSF56349 26 339 8.54E-22 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS10000 a8c71f354d4bd44799fe840301c27040 374 Pfam PF00589 Phage integrase family 278 339 1.0E-5 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 SUPERFAMILY SSF52833 7 89 8.24E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 Gene3D G3DSA:1.20.1050.10 99 203 1.2E-23 T 28-03-2018 AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 16 80 4.7E-9 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 Gene3D G3DSA:3.40.30.10 1 98 6.3E-22 T 28-03-2018 AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 SUPERFAMILY SSF47616 81 200 2.73E-27 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS16870 791e135db7fdd95569cf9e36ccc298f2 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 116 195 1.8E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 SUPERFAMILY SSF51182 78 188 2.46E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 SUPERFAMILY SSF47413 5 74 1.42E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 Gene3D G3DSA:1.10.260.40 1 73 3.5E-17 T 28-03-2018 AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 Pfam PF07883 Cupin domain 132 187 2.5E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 Gene3D G3DSA:2.60.120.10 74 195 3.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 Pfam PF01381 Helix-turn-helix 17 69 4.9E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS13870 26909572ad2b975bd5ba6782e5dbafea 195 SMART SM00530 14 69 3.9E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 294 8.0E-36 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 PIRSF PIRSF000103 1 298 8.7E-84 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 Gene3D G3DSA:1.10.1040.10 165 298 2.6E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 7 295 3.7E-126 T 28-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 SUPERFAMILY SSF48179 165 296 9.41E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 8.2E-53 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 Gene3D G3DSA:3.40.50.720 2 164 2.5E-34 T 28-03-2018 AFA_RS10080 3d19fc0af46235736d407cefa6b3b3f0 298 SUPERFAMILY SSF51735 4 164 1.31E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 Gene3D G3DSA:1.20.200.10 140 415 8.5E-78 T 28-03-2018 AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 Gene3D G3DSA:1.10.275.10 2 139 1.0E-53 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 Pfam PF00206 Lyase 13 343 4.0E-93 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 6.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 6.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 6.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 6.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 Pfam PF10415 Fumarase C C-terminus 409 461 3.3E-18 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 Gene3D G3DSA:1.10.40.30 416 463 2.9E-18 T 28-03-2018 AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 SUPERFAMILY SSF48557 4 459 6.04E-143 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS14315 755c2953e1dd7889eaf2e042ede86631 472 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFA_RS15900 765faff3dea2e411c176c7328df48515 296 Gene3D G3DSA:3.40.190.10 90 176 4.6E-16 T 28-03-2018 AFA_RS15900 765faff3dea2e411c176c7328df48515 296 SUPERFAMILY SSF53850 89 294 1.99E-41 T 28-03-2018 AFA_RS15900 765faff3dea2e411c176c7328df48515 296 Gene3D G3DSA:3.40.190.10 177 262 5.5E-19 T 28-03-2018 AFA_RS15900 765faff3dea2e411c176c7328df48515 296 Pfam PF03466 LysR substrate binding domain 88 291 5.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15900 765faff3dea2e411c176c7328df48515 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15900 765faff3dea2e411c176c7328df48515 296 Gene3D G3DSA:1.10.10.10 3 89 4.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15900 765faff3dea2e411c176c7328df48515 296 SUPERFAMILY SSF46785 4 87 1.01E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10615 377252e2d2a72a1959151963f3d02230 87 SUPERFAMILY SSF160766 1 86 3.66E-32 T 28-03-2018 IPR023122 NE1680-like domain AFA_RS10615 377252e2d2a72a1959151963f3d02230 87 Pfam PF09630 Domain of unknown function (DUF2024) 1 83 9.0E-30 T 28-03-2018 IPR018592 Protein of unknown function DUF2024 AFA_RS10615 377252e2d2a72a1959151963f3d02230 87 Gene3D G3DSA:3.10.510.10 1 86 9.9E-33 T 28-03-2018 IPR023122 NE1680-like domain AFA_RS02090 ba4ace07114c6ecd0afee7a420a03326 340 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 47 323 6.8E-79 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS02090 ba4ace07114c6ecd0afee7a420a03326 340 Gene3D G3DSA:3.40.190.10 1 326 3.3E-10 T 28-03-2018 AFA_RS02090 ba4ace07114c6ecd0afee7a420a03326 340 PIRSF PIRSF006470 8 340 3.4E-88 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS02090 ba4ace07114c6ecd0afee7a420a03326 340 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 50 298 2.3E-64 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 839 19.904 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SMART SM00957 5 402 8.5E-301 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 824 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Gene3D G3DSA:3.40.50.300 417 640 4.4E-57 T 28-03-2018 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Gene3D G3DSA:1.10.3060.10 641 750 1.5E-29 T 28-03-2018 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Gene3D G3DSA:1.10.3060.10 751 848 4.2E-24 T 28-03-2018 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 ProSitePatterns PS01312 SecA family signature. 500 515 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 62 86 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 339 361 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 116 126 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 169 189 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 100 114 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 413 426 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 PRINTS PR00906 SecA protein signature 376 393 1.2E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Pfam PF02810 SEC-C motif 889 907 1.1E-10 T 28-03-2018 IPR004027 SEC-C motif AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Pfam PF07517 SecA DEAD-like domain 5 402 7.5E-130 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Pfam PF01043 SecA preprotein cross-linking domain 232 358 6.3E-35 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SMART SM00958 227 358 5.3E-75 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Pfam PF07516 SecA Wing and Scaffold domain 624 836 2.1E-66 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Gene3D G3DSA:3.90.1440.10 243 368 1.4E-40 T 28-03-2018 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF81886 885 897 1.96E-79 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF81886 628 847 1.96E-79 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF81767 226 368 1.7E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF52540 416 625 8.57E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 Gene3D G3DSA:3.40.50.300 8 242 4.7E-54 T 28-03-2018 AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF52540 368 415 8.19E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03710 4752c844ebedf561eaf4c9d82c696543 909 SUPERFAMILY SSF52540 4 227 8.19E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03950 ca90f1dda9c9e88803c6d25c8ee7f15d 106 Pfam PF13670 Peptidase propeptide and YPEB domain 8 87 1.3E-25 T 28-03-2018 IPR025711 PepSY domain AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 SUPERFAMILY SSF54534 82 157 6.28E-24 T 28-03-2018 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 Gene3D G3DSA:1.10.287.180 3 75 8.2E-33 T 28-03-2018 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 SUPERFAMILY SSF46557 4 77 1.7E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 1.3E-32 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.856 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 4.1E-29 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 1.1E-57 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 Gene3D G3DSA:3.10.50.30 78 158 6.9E-28 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 PIRSF PIRSF006092 1 158 1.9E-53 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AFA_RS04155 09c157d362bb98c569e8f0bfb79135d1 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SUPERFAMILY SSF46600 191 242 8.11E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SUPERFAMILY SSF47781 522 607 5.08E-18 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Gene3D G3DSA:3.40.1440.10 3 101 4.0E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Pfam PF01541 GIY-YIG catalytic domain 19 93 6.9E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Pfam PF02151 UvrB/uvrC motif 205 236 2.0E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SMART SM00465 17 98 4.6E-19 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 540 1.5E-45 T 28-03-2018 IPR001162 UvrC family homology region AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Gene3D G3DSA:1.10.150.20 567 607 4.9E-12 T 28-03-2018 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 605 26.602 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Gene3D G3DSA:1.10.150.20 521 566 0.42 T 28-03-2018 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 587 3.7E-169 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Pfam PF14520 Helix-hairpin-helix domain 555 607 1.9E-7 T 28-03-2018 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SUPERFAMILY SSF82771 16 100 4.18E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 Gene3D G3DSA:4.10.860.10 181 243 2.9E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SMART SM00278 586 605 20.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS11800 7bb37e6669ef5bffcba34efa6f192519 607 SMART SM00278 554 573 4.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS09175 dba5aca1656e3c0a60feec9a182ca6a4 325 Gene3D G3DSA:3.40.190.10 124 237 1.5E-9 T 28-03-2018 AFA_RS09175 dba5aca1656e3c0a60feec9a182ca6a4 325 SUPERFAMILY SSF53850 115 294 1.41E-10 T 28-03-2018 AFA_RS09175 dba5aca1656e3c0a60feec9a182ca6a4 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 4.4E-75 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS09175 dba5aca1656e3c0a60feec9a182ca6a4 325 PIRSF PIRSF017082 1 324 3.4E-70 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Pfam PF09334 tRNA synthetases class I (M) 5 407 1.3E-137 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:2.20.28.20 139 172 2.2E-13 T 28-03-2018 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 SUPERFAMILY SSF57770 139 173 1.14E-11 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 262 273 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 PRINTS PR01041 Methionyl-tRNA synthetase signature 301 316 7.0E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:3.40.50.620 1 78 6.2E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 SUPERFAMILY SSF50249 583 688 4.9E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 573 688 4.4E-38 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:2.40.50.140 575 689 2.5E-28 T 28-03-2018 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:3.40.50.620 261 383 1.9E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Pfam PF01588 Putative tRNA binding domain 589 678 3.0E-22 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 SUPERFAMILY SSF52374 3 138 2.35E-91 T 28-03-2018 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 SUPERFAMILY SSF52374 173 395 2.35E-91 T 28-03-2018 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:1.10.730.10 384 553 9.3E-25 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 SUPERFAMILY SSF47323 397 597 1.53E-24 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 562 36.793 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 Gene3D G3DSA:2.170.220.10 178 260 6.2E-11 T 28-03-2018 AFA_RS02550 dc6a34ddeda824f3a2997c57433fb4bd 689 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 547 7.1E-152 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 SUPERFAMILY SSF48264 6 379 2.23E-57 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 316 331 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 271 282 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 151 166 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 337 346 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 346 357 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 85 96 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 288 315 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 PRINTS PR00359 B-class P450 signature 134 150 1.9E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 Gene3D G3DSA:1.10.630.10 10 396 3.8E-44 T 28-03-2018 AFA_RS04375 3a097ea0382adc81b216364bd27555bb 398 Pfam PF00067 Cytochrome P450 269 364 1.9E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 5.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 2.3E-58 T 28-03-2018 AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 Gene3D G3DSA:3.40.50.720 42 253 1.5E-63 T 28-03-2018 AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 Gene3D G3DSA:3.40.50.720 3 41 4.9E-6 T 28-03-2018 AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 SUPERFAMILY SSF51735 9 252 1.37E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09975 70cb5e6206201cb18d689ce0e6a868ae 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Gene3D G3DSA:2.40.30.10 295 406 4.9E-32 T 28-03-2018 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF50447 310 407 1.35E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF50447 256 281 1.35E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Gene3D G3DSA:3.30.70.240 615 693 1.3E-30 T 28-03-2018 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Pfam PF03764 Elongation factor G, domain IV 484 604 6.9E-47 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Pfam PF00679 Elongation factor G C-terminus 606 693 2.9E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 3.5E-65 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 106.757 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF52540 6 288 3.18E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Pfam PF14492 Elongation Factor G, domain II 409 483 7.4E-34 T 28-03-2018 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Pfam PF03144 Elongation factor Tu domain 2 329 396 4.8E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF54211 484 605 1.87E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF54980 407 485 2.73E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Gene3D G3DSA:3.30.70.870 407 498 1.2E-38 T 28-03-2018 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 184 2.9E-31 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SUPERFAMILY SSF54980 609 700 5.28E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Gene3D G3DSA:3.30.230.10 499 614 6.9E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SMART SM00889 485 604 5.7E-72 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 Gene3D G3DSA:3.40.50.300 1 293 7.2E-54 T 28-03-2018 AFA_RS10300 59a11cf616212e8b4ef92250f15e03c0 705 SMART SM00838 606 694 1.8E-53 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Gene3D G3DSA:3.40.50.20 1 133 2.1E-40 T 28-03-2018 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 SUPERFAMILY SSF52440 1 126 1.47E-31 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 128 301 2.9E-75 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 316 2.5E-121 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Gene3D G3DSA:3.30.470.20 196 304 1.1E-13 T 28-03-2018 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 124 1.3E-35 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 SUPERFAMILY SSF56059 128 315 1.12E-58 T 28-03-2018 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Hamap MF_00162 Glutathione synthetase [gshB]. 1 320 150.388 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFA_RS08675 46c87d39d326804d6c19589b696d9da9 320 Gene3D G3DSA:3.30.1490.20 142 195 1.6E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 Gene3D G3DSA:1.10.10.60 209 259 4.1E-6 T 28-03-2018 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 SUPERFAMILY SSF46689 261 311 4.12E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 Pfam PF12833 Helix-turn-helix domain 231 310 4.5E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 Pfam PF14525 AraC-binding-like domain 16 181 3.8E-24 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 305 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 293 4.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 309 4.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 Gene3D G3DSA:1.10.10.60 260 314 5.7E-14 T 28-03-2018 AFA_RS01730 c0694bb14fa6dfac48ab78892a054531 316 SMART SM00342 225 309 9.8E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 Pfam PF01966 HD domain 157 278 1.4E-19 T 28-03-2018 IPR006674 HD domain AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 SUPERFAMILY SSF52172 7 132 1.57E-39 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 Gene3D G3DSA:1.10.3210.10 131 328 5.7E-53 T 28-03-2018 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 SMART SM00448 9 121 1.4E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 Gene3D G3DSA:3.40.50.2300 2 130 1.8E-34 T 28-03-2018 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 SUPERFAMILY SSF109604 131 319 6.6E-42 T 28-03-2018 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 Pfam PF00072 Response regulator receiver domain 12 121 6.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06610 edd6863342d5878741a315e6e3b1b99f 338 SMART SM00471 151 288 1.4E-9 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS03880 49f3ce50fb9c1113e13ad06d853eee64 403 SUPERFAMILY SSF103473 13 394 3.66E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS03880 49f3ce50fb9c1113e13ad06d853eee64 403 Pfam PF07690 Major Facilitator Superfamily 26 333 9.0E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS03880 49f3ce50fb9c1113e13ad06d853eee64 403 Gene3D G3DSA:1.20.1250.20 2 198 3.2E-23 T 28-03-2018 AFA_RS03880 49f3ce50fb9c1113e13ad06d853eee64 403 Gene3D G3DSA:1.20.1250.20 201 401 4.9E-16 T 28-03-2018 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 Gene3D G3DSA:1.10.3720.10 320 545 1.3E-27 T 28-03-2018 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 Gene3D G3DSA:1.10.3720.10 43 267 1.4E-28 T 28-03-2018 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 263 2.0E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 356 538 7.6E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 SUPERFAMILY SSF161098 5 261 2.43E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09330 b848550998658183c33e52a4e799d94a 554 SUPERFAMILY SSF161098 288 543 4.06E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 Gene3D G3DSA:3.40.47.10 1 152 5.0E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 7.6E-148 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 PIRSF PIRSF000429 1 394 1.1E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 SUPERFAMILY SSF53901 273 392 4.74E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 SUPERFAMILY SSF53901 4 271 9.52E-90 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 Pfam PF00108 Thiolase, N-terminal domain 5 263 1.5E-102 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 Pfam PF02803 Thiolase, C-terminal domain 272 392 1.4E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 Gene3D G3DSA:3.40.47.10 153 266 2.8E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 Gene3D G3DSA:3.40.47.10 267 391 2.1E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS14005 e792189401b5cf036fdffdc035cb5e0a 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 SUPERFAMILY SSF56024 221 384 2.06E-33 T 28-03-2018 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 Gene3D G3DSA:3.30.870.10 224 386 1.2E-26 T 28-03-2018 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 Pfam PF13091 PLD-like domain 244 367 1.0E-22 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 Pfam PF13091 PLD-like domain 29 139 2.2E-15 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 Hamap MF_01917 Cardiolipin synthase B [clsB]. 7 413 43.41 T 28-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 SUPERFAMILY SSF56024 8 183 2.92E-41 T 28-03-2018 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 Gene3D G3DSA:3.30.870.10 3 221 1.2E-32 T 28-03-2018 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 SMART SM00155 316 342 0.014 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS17605 1676cafd21452262c138d04185bde48c 413 SMART SM00155 116 143 0.0074 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 SUPERFAMILY SSF110849 11 105 3.14E-10 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 SUPERFAMILY SSF109709 95 185 7.59E-21 T 28-03-2018 AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 SMART SM00470 6 103 8.0E-6 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 Gene3D G3DSA:3.90.1530.10 1 103 2.4E-14 T 28-03-2018 AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 Pfam PF02195 ParB-like nuclease domain 8 73 1.3E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS12280 05b9f2f6ce01c955e8c2f020bbd31bf4 643 Gene3D G3DSA:1.10.10.730 104 149 3.9E-11 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SUPERFAMILY SSF56091 4 340 7.92E-115 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:1.10.287.610 2 65 2.1E-26 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SUPERFAMILY SSF50249 342 424 5.82E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:1.10.150.20 456 529 3.7E-26 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 431 458 4.5E-11 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 618 692 1.0E-11 T 28-03-2018 IPR001357 BRCT domain AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:2.40.50.140 341 414 6.5E-34 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 PIRSF PIRSF001604 1 695 4.5E-244 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 9 688 1.2E-251 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:3.30.470.30 123 276 2.8E-51 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF14520 Helix-hairpin-helix domain 470 525 2.3E-8 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 346 421 1.4E-35 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:3.40.50.10190 596 695 2.2E-25 T 28-03-2018 IPR001357 BRCT domain AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Hamap MF_01588 DNA ligase [ligA]. 4 692 53.508 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF12826 Helix-hairpin-helix motif 534 596 1.4E-26 T 28-03-2018 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SUPERFAMILY SSF52113 619 692 4.3E-17 T 28-03-2018 IPR001357 BRCT domain AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00278 536 555 200.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00278 470 489 15.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00278 504 523 6.6 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00278 568 587 190.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 4 342 9.1E-120 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00292 618 695 1.7E-11 T 28-03-2018 IPR001357 BRCT domain AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SMART SM00532 1 472 4.9E-255 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 SUPERFAMILY SSF47781 428 607 8.15E-62 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 355 370 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 119 148 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site AFA_RS13280 696aacf6c5abce797fa6a973ce850c2f 695 Gene3D G3DSA:1.10.150.20 530 595 9.6E-32 T 28-03-2018 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 SMART SM00240 20 70 8.1E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 SUPERFAMILY SSF49879 21 94 5.88E-19 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 Gene3D G3DSA:3.30.450.90 215 319 1.7E-34 T 28-03-2018 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 Gene3D G3DSA:3.40.50.300 320 527 1.2E-13 T 28-03-2018 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 Pfam PF00437 Type II/IV secretion system protein 220 496 1.5E-83 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 SUPERFAMILY SSF52540 203 528 1.95E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10890 c649f20030330d5d373d58da2afba226 549 Pfam PF00498 FHA domain 23 85 6.0E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AFA_RS10890 c649f20030330d5d373d58da2afba226 549 Gene3D G3DSA:2.60.200.20 4 161 4.9E-16 T 28-03-2018 AFA_RS02410 797a3473016cb508b753249f90461261 203 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 62 176 2.7E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS02410 797a3473016cb508b753249f90461261 203 SMART SM00644 27 175 7.6E-45 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS02410 797a3473016cb508b753249f90461261 203 SUPERFAMILY SSF55846 21 187 1.7E-59 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS02410 797a3473016cb508b753249f90461261 203 Gene3D G3DSA:3.40.80.10 9 188 4.9E-48 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS15950 a588d33013d952c8ffe6c98368882ca6 279 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 6.7E-50 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS15950 a588d33013d952c8ffe6c98368882ca6 279 Gene3D G3DSA:3.90.226.10 1 268 2.3E-69 T 28-03-2018 AFA_RS15950 a588d33013d952c8ffe6c98368882ca6 279 SUPERFAMILY SSF52096 6 263 1.28E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS08375 de44528a83568194f93be494df3373f1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 4.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08375 de44528a83568194f93be494df3373f1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 140 160 4.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08375 de44528a83568194f93be494df3373f1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 4.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08375 de44528a83568194f93be494df3373f1 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 4.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08375 de44528a83568194f93be494df3373f1 169 Gene3D G3DSA:1.10.10.10 1 169 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08375 de44528a83568194f93be494df3373f1 169 SUPERFAMILY SSF46785 6 165 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08375 de44528a83568194f93be494df3373f1 169 SMART SM00347 47 150 8.4E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08375 de44528a83568194f93be494df3373f1 169 Pfam PF12802 MarR family 52 114 2.5E-12 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Gene3D G3DSA:3.30.460.10 235 372 2.1E-36 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Gene3D G3DSA:3.10.20.30 429 504 1.3E-22 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SUPERFAMILY SSF81301 228 439 7.03E-58 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SUPERFAMILY SSF109604 53 237 1.16E-69 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Pfam PF13291 ACT domain 683 756 2.0E-15 T 28-03-2018 IPR002912 ACT domain AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SMART SM00954 282 392 5.5E-58 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Pfam PF02824 TGS domain 435 494 1.4E-19 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Gene3D G3DSA:3.30.70.260 680 758 1.8E-8 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SUPERFAMILY SSF55021 684 756 5.5E-7 T 28-03-2018 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SMART SM00471 88 200 1.4E-10 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 73 754 1.0E-221 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 SUPERFAMILY SSF81271 422 495 1.13E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Pfam PF13328 HD domain 73 222 4.5E-50 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS10485 155af3309bf1a39f065d096a52d96791 759 Pfam PF04607 Region found in RelA / SpoT proteins 282 391 3.8E-31 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 SUPERFAMILY SSF53649 152 182 4.28E-105 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 SUPERFAMILY SSF53649 215 515 4.28E-105 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 SUPERFAMILY SSF53649 6 110 4.28E-105 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 Pfam PF00884 Sulfatase 6 414 3.1E-53 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 Gene3D G3DSA:3.40.720.10 2 373 9.7E-75 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 Gene3D G3DSA:3.40.720.10 374 441 1.2E-6 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS15020 4d3b8000dacfd467dbebff17209b72c5 529 Gene3D G3DSA:3.30.1120.10 448 522 1.7E-6 T 28-03-2018 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:1.10.287.560 307 369 2.0E-19 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 554 1.0E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SUPERFAMILY SSF55874 373 553 2.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Pfam PF01584 CheW-like domain 560 686 1.7E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:1.20.120.160 4 161 1.2E-30 T 28-03-2018 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SUPERFAMILY SSF47384 309 371 8.63E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:3.30.565.10 370 556 3.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:2.30.30.40 634 686 2.4E-19 T 28-03-2018 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SMART SM00387 415 555 1.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Pfam PF09078 CheY binding 168 230 7.1E-22 T 28-03-2018 IPR015162 CheY binding AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:2.40.50.180 578 633 4.8E-9 T 28-03-2018 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 9.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 9.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 9.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 509 9.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Pfam PF01627 Hpt domain 10 96 2.1E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Gene3D G3DSA:3.30.70.400 166 231 5.0E-23 T 28-03-2018 IPR015162 CheY binding AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 309 370 8.9E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SUPERFAMILY SSF50341 554 686 9.42E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SMART SM01231 307 370 1.1E-21 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SMART SM00260 547 687 2.4E-38 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SUPERFAMILY SSF55052 167 231 2.51E-17 T 28-03-2018 IPR015162 CheY binding AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SMART SM00073 7 105 2.7E-29 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AFA_RS05745 80b68fbe2a2ccad08bfb829c0a782666 698 SUPERFAMILY SSF47226 7 129 3.18E-30 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 SUPERFAMILY SSF53383 7 436 4.67E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 Pfam PF00202 Aminotransferase class-III 7 435 1.8E-98 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 Gene3D G3DSA:3.90.1150.10 1 178 4.6E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 PIRSF PIRSF000521 1 412 7.8E-33 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 Gene3D G3DSA:3.40.640.10 179 312 2.4E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS01920 b37ffe3ade73f903691287c2be2dcf40 441 Gene3D G3DSA:3.90.1150.10 313 438 2.8E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 Gene3D G3DSA:1.20.20.10 3 75 1.0E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.054 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 Pfam PF00137 ATP synthase subunit C 9 71 1.4E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 SUPERFAMILY SSF81333 4 77 1.02E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFA_RS16625 2fe6d017742355bddc3dc19735ee00c2 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 3.6E-21 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFA_RS01540 67928863b13c462ea6e5964026353006 251 SUPERFAMILY SSF53474 6 245 1.52E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01540 67928863b13c462ea6e5964026353006 251 Pfam PF12146 Serine aminopeptidase, S33 81 169 5.1E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 AFA_RS01540 67928863b13c462ea6e5964026353006 251 Gene3D G3DSA:3.40.50.1820 2 251 5.0E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Gene3D G3DSA:1.10.390.10 283 462 2.7E-46 T 28-03-2018 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 5.3E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 5.3E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 312 5.3E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 328 5.3E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Pfam PF01433 Peptidase family M1 domain 213 444 3.3E-52 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Gene3D G3DSA:1.25.50.10 569 891 8.7E-113 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 890 0.0 T 28-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 SUPERFAMILY SSF63737 6 196 2.48E-40 T 28-03-2018 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 571 890 9.8E-108 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 463 567 1.1E-24 T 28-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 SUPERFAMILY SSF55486 213 469 7.14E-68 T 28-03-2018 AFA_RS12665 6bec6a0f2ada1080318249797cb6ba05 892 Gene3D G3DSA:2.60.40.1730 17 197 2.1E-24 T 28-03-2018 AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 Gene3D G3DSA:3.40.50.300 1 233 2.1E-55 T 28-03-2018 AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 SUPERFAMILY SSF52540 2 231 1.09E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 Pfam PF00005 ABC transporter 17 161 4.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 PIRSF PIRSF039137 1 233 2.8E-105 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 AFA_RS09415 9330eadac25d3a785baaea8a0c9c29c1 233 SMART SM00382 26 227 2.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Gene3D G3DSA:3.30.559.10 165 403 1.6E-90 T 28-03-2018 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Pfam PF02817 e3 binding domain 116 149 1.4E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 175 403 4.4E-81 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Gene3D G3DSA:3.90.1170.30 2 47 9.0E-13 T 28-03-2018 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 SUPERFAMILY SSF52777 175 404 1.47E-88 T 28-03-2018 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 5 405 9.2E-172 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 SUPERFAMILY SSF47005 109 151 2.75E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Gene3D G3DSA:4.10.320.10 116 164 1.3E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Pfam PF00364 Biotin-requiring enzyme 5 77 6.8E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 SUPERFAMILY SSF51230 2 97 1.96E-27 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS04895 65fbbb479691e7878a803c62f0b50185 405 Gene3D G3DSA:2.40.50.100 48 115 7.6E-8 T 28-03-2018 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Gene3D G3DSA:1.25.40.10 253 378 6.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 SUPERFAMILY SSF48452 86 210 1.64E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Gene3D G3DSA:1.25.40.10 84 172 0.0023 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Pfam PF07219 HemY protein N-terminus 26 135 4.0E-24 T 28-03-2018 IPR010817 HemY, N-terminal AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 SUPERFAMILY SSF48452 270 396 7.05E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Gene3D G3DSA:1.25.40.10 173 252 8.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Gene3D G3DSA:1.25.40.10 379 439 0.0011 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 Pfam PF13181 Tetratricopeptide repeat 366 393 4.7E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS10950 2a34120866e4d3730368eb9c59b1f6ca 501 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 3 389 2.9E-84 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 595 1.8E-26 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Gene3D G3DSA:2.40.110.10 158 270 5.8E-23 T 28-03-2018 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 155 7.0E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 SUPERFAMILY SSF47203 292 467 6.44E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Gene3D G3DSA:1.20.140.10 282 467 7.0E-44 T 28-03-2018 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 SUPERFAMILY SSF56645 38 268 2.75E-57 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 451 7.2E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 33 4.8E-9 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Gene3D G3DSA:1.10.540.10 22 157 1.1E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS11900 8b6f2c0feba59aa8df1ec409bda44ebe 605 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 266 1.8E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS02115 b7caa942948a3bf0d73c9b8cc9a2a687 275 TIGRFAM TIGR00552 nadE: NAD+ synthetase 23 273 1.3E-61 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AFA_RS02115 b7caa942948a3bf0d73c9b8cc9a2a687 275 Pfam PF02540 NAD synthase 28 272 8.2E-60 T 28-03-2018 IPR022310 NAD/GMP synthase AFA_RS02115 b7caa942948a3bf0d73c9b8cc9a2a687 275 Gene3D G3DSA:3.40.50.620 7 275 7.2E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS02115 b7caa942948a3bf0d73c9b8cc9a2a687 275 SUPERFAMILY SSF52402 9 273 2.62E-72 T 28-03-2018 AFA_RS02115 b7caa942948a3bf0d73c9b8cc9a2a687 275 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 22 275 31.211 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 AFA_RS02785 219782512c21566b1a51091f09325683 275 Pfam PF06827 Zinc finger found in FPG and IleRS 246 274 6.1E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFA_RS02785 219782512c21566b1a51091f09325683 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.3E-79 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFA_RS02785 219782512c21566b1a51091f09325683 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 3.1E-22 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFA_RS02785 219782512c21566b1a51091f09325683 275 SMART SM01232 133 225 2.1E-41 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFA_RS02785 219782512c21566b1a51091f09325683 275 SUPERFAMILY SSF46946 134 226 9.13E-27 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFA_RS02785 219782512c21566b1a51091f09325683 275 SMART SM00898 2 115 3.7E-43 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFA_RS02785 219782512c21566b1a51091f09325683 275 Gene3D G3DSA:1.10.8.50 135 275 5.7E-44 T 28-03-2018 AFA_RS02785 219782512c21566b1a51091f09325683 275 SUPERFAMILY SSF57716 221 273 1.14E-13 T 28-03-2018 AFA_RS02785 219782512c21566b1a51091f09325683 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.1E-27 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFA_RS02785 219782512c21566b1a51091f09325683 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 38.134 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFA_RS02785 219782512c21566b1a51091f09325683 275 Gene3D G3DSA:3.20.190.10 2 134 4.2E-34 T 28-03-2018 AFA_RS02785 219782512c21566b1a51091f09325683 275 SUPERFAMILY SSF81624 2 142 5.36E-35 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 Gene3D G3DSA:3.10.20.80 4 80 1.5E-30 T 28-03-2018 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 9.2E-71 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 SUPERFAMILY SSF55200 84 172 5.62E-35 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 31.495 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 SUPERFAMILY SSF54364 7 79 1.44E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 Gene3D G3DSA:3.30.110.10 81 174 6.1E-37 T 28-03-2018 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 1.4E-39 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 AFA_RS08670 c9801e8aa83c4b6515eb14e92cebfa74 174 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 7.4E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 SUPERFAMILY SSF46689 268 320 1.03E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 268 313 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 Gene3D G3DSA:1.10.10.60 268 325 1.5E-12 T 28-03-2018 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 Gene3D G3DSA:1.10.10.60 150 267 2.1E-14 T 28-03-2018 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 Pfam PF12833 Helix-turn-helix domain 238 319 1.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 SMART SM00342 231 317 3.2E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 Pfam PF14525 AraC-binding-like domain 20 196 1.2E-38 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS00385 0e0ac684d6681bd261a8cc11f63d8a3a 325 SUPERFAMILY SSF46689 215 266 1.61E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 SMART SM00304 70 122 5.6E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 SMART SM00283 123 370 1.9E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 182 337 1.1E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 Gene3D G3DSA:1.10.287.950 179 373 2.0E-46 T 28-03-2018 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 Gene3D G3DSA:1.10.287.950 77 178 2.2E-18 T 28-03-2018 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 SUPERFAMILY SSF58104 90 371 8.63E-73 T 28-03-2018 AFA_RS05875 9dbbcd8ff81328d44f185aed0b193786 466 Pfam PF00672 HAMP domain 70 118 3.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS14120 b9cdc5fd035ea77cbb64726837bd45c8 466 SUPERFAMILY SSF56954 4 458 1.31E-77 T 28-03-2018 AFA_RS14120 b9cdc5fd035ea77cbb64726837bd45c8 466 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 9 458 3.2E-75 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS14120 b9cdc5fd035ea77cbb64726837bd45c8 466 Gene3D G3DSA:1.20.1600.10 17 463 3.3E-74 T 28-03-2018 AFA_RS14120 b9cdc5fd035ea77cbb64726837bd45c8 466 Pfam PF02321 Outer membrane efflux protein 276 456 2.3E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS14120 b9cdc5fd035ea77cbb64726837bd45c8 466 Pfam PF02321 Outer membrane efflux protein 59 249 2.0E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 Gene3D G3DSA:3.10.20.30 232 336 8.5E-18 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 259 327 4.5E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 Pfam PF00175 Oxidoreductase NAD-binding domain 128 220 2.5E-7 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 SUPERFAMILY SSF63380 18 115 2.15E-27 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 SUPERFAMILY SSF54292 226 335 7.21E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 287 295 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 55 67 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 67 81 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 206 214 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 45 55 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 152 161 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 127 146 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 PRINTS PR00409 Phthalate dioxygenase reductase family signature 105 119 1.1E-46 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 Gene3D G3DSA:3.40.50.80 117 231 6.8E-23 T 28-03-2018 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 Gene3D G3DSA:2.40.30.10 13 116 8.9E-16 T 28-03-2018 AFA_RS00075 ffc92a3429b244abc949353a42e9b2ed 336 SUPERFAMILY SSF52343 116 234 1.19E-28 T 28-03-2018 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 SUPERFAMILY SSF52172 5 131 1.42E-19 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 Gene3D G3DSA:3.40.50.2300 4 159 5.1E-17 T 28-03-2018 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 SMART SM00342 169 252 3.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 Pfam PF12833 Helix-turn-helix domain 175 253 4.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 Gene3D G3DSA:1.10.10.60 206 258 2.0E-12 T 28-03-2018 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 SUPERFAMILY SSF46689 206 254 2.28E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 Gene3D G3DSA:1.10.10.60 160 205 9.8E-8 T 28-03-2018 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 SMART SM00448 7 120 3.9E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 Pfam PF00072 Response regulator receiver domain 25 120 1.5E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 206 248 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 221 236 2.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS01875 1bbef7abf62f793631fa1ebc9e7dabad 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 252 2.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.30.470.20 746 928 2.3E-44 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.30.470.20 119 410 2.8E-67 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.209 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF52440 558 677 3.45E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 1.1E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF56059 675 935 4.0E-104 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF56059 128 408 6.72E-107 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 171 185 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Pfam PF02142 MGS-like domain 958 1043 2.6E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 2.2E-42 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 877 1.1E-36 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 7.4E-70 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.40.50.20 4 115 4.3E-38 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.30.1490.20 657 745 1.7E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:1.10.1030.10 411 540 4.8E-53 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.40.50.1380 929 1057 1.1E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Gene3D G3DSA:3.40.50.20 541 656 5.4E-62 T 28-03-2018 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SMART SM00851 957 1044 1.7E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF52440 1 127 1.32E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SMART SM01096 426 549 2.4E-75 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.485 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF48108 403 556 3.27E-54 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04130 5b17c4ff1fc6c3b30d1caad4e710daa8 1080 SUPERFAMILY SSF52335 939 1076 1.44E-36 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Pfam PF16658 Class II release factor RF3, C-terminal domain 385 513 1.3E-43 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 SUPERFAMILY SSF54980 390 463 2.41E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Pfam PF03144 Elongation factor Tu domain 2 312 378 1.8E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 SUPERFAMILY SSF50447 259 389 1.39E-27 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 526 50.782 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 528 4.8E-209 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Gene3D G3DSA:2.40.30.10 266 382 8.3E-19 T 28-03-2018 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 148 1.3E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Pfam PF00009 Elongation factor Tu GTP binding domain 12 276 1.8E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 SUPERFAMILY SSF52540 10 276 3.7E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Gene3D G3DSA:3.40.50.300 82 265 5.8E-30 T 28-03-2018 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.7E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 PRINTS PR00315 GTP-binding elongation factor signature 65 73 2.7E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.7E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 PRINTS PR00315 GTP-binding elongation factor signature 137 146 2.7E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.7E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Gene3D G3DSA:3.30.70.870 392 466 8.6E-12 T 28-03-2018 AFA_RS00830 375af51ee69b1abad427223c72765cfd 537 Gene3D G3DSA:3.40.50.300 5 81 4.5E-7 T 28-03-2018 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.656 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 SUPERFAMILY SSF56059 1 238 5.89E-83 T 28-03-2018 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 SUPERFAMILY SSF52210 239 385 4.32E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Pfam PF00549 CoA-ligase 262 381 1.2E-24 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Gene3D G3DSA:3.40.50.261 240 385 1.4E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 PIRSF PIRSF001554 1 386 1.5E-150 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Gene3D G3DSA:3.30.1490.20 21 96 1.7E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Gene3D G3DSA:3.30.470.20 97 239 2.0E-52 T 28-03-2018 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 Pfam PF08442 ATP-grasp domain 2 202 5.6E-78 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10980 1d8c33f1c91519deb27942d17158ee57 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 6.1E-156 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS00275 bfa5936e401adffb07829c8e7359e3d2 374 Pfam PF07883 Cupin domain 107 180 9.9E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS00275 bfa5936e401adffb07829c8e7359e3d2 374 Pfam PF07883 Cupin domain 279 344 1.8E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS00275 bfa5936e401adffb07829c8e7359e3d2 374 Gene3D G3DSA:2.60.120.10 42 365 1.2E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS00275 bfa5936e401adffb07829c8e7359e3d2 374 SUPERFAMILY SSF51182 21 371 8.46E-120 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS04305 bd8825793683ba86d1365dc71c841aba 572 Pfam PF00474 Sodium:solute symporter family 68 489 1.4E-114 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS04305 bd8825793683ba86d1365dc71c841aba 572 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 68 488 6.1E-62 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS04305 bd8825793683ba86d1365dc71c841aba 572 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 183 208 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 SUPERFAMILY SSF46785 21 92 3.17E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 Pfam PF09339 IclR helix-turn-helix domain 23 74 6.2E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 Pfam PF01614 Bacterial transcriptional regulator 137 260 1.7E-30 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 SUPERFAMILY SSF55781 85 264 4.17E-47 T 28-03-2018 IPR029016 GAF domain-like AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 Gene3D G3DSA:1.10.10.10 13 90 3.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 SMART SM00346 21 109 4.4E-28 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14845 2a8b61f541aff39c3f92938fbf9cbf95 266 Gene3D G3DSA:3.30.450.40 91 266 1.8E-49 T 28-03-2018 IPR029016 GAF domain-like AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Gene3D G3DSA:3.30.870.10 329 501 1.4E-20 T 28-03-2018 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Pfam PF02503 Polyphosphate kinase middle domain 124 321 1.2E-58 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Pfam PF13089 Polyphosphate kinase N-terminal domain 10 114 3.1E-32 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 9 685 5.2E-278 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Gene3D G3DSA:3.30.1840.10 114 310 3.0E-58 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Gene3D G3DSA:1.20.58.310 11 113 9.3E-32 T 28-03-2018 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Hamap MF_00347 Polyphosphate kinase [ppk]. 7 689 27.799 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 SUPERFAMILY SSF143724 117 317 6.87E-61 T 28-03-2018 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 SUPERFAMILY SSF56024 331 499 3.14E-53 T 28-03-2018 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 SUPERFAMILY SSF56024 508 686 3.59E-66 T 28-03-2018 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 SUPERFAMILY SSF140356 7 108 3.66E-31 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 PIRSF PIRSF015589 3 689 7.0E-256 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Pfam PF13090 Polyphosphate kinase C-terminal domain 339 684 1.0E-148 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 AFA_RS04195 4d1ec6aca7c3b173ce71b4ae7b53236b 690 Gene3D G3DSA:3.30.870.10 506 688 1.0E-36 T 28-03-2018 AFA_RS09630 7166eb72acdaed4245755f94de3399a6 463 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 40 453 7.2E-117 T 28-03-2018 IPR021204 Integrating conjugative element protein, PFL4711 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 Gene3D G3DSA:1.10.10.60 2 55 1.7E-16 T 28-03-2018 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 5.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 5.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 Gene3D G3DSA:1.10.357.10 56 195 2.2E-10 T 28-03-2018 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 1.5E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS17840 be37544400845d7d31eb25f8f5108a45 196 SUPERFAMILY SSF46689 3 78 1.5E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 SUPERFAMILY SSF54999 5 101 2.49E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 Gene3D G3DSA:3.30.70.600 3 103 2.7E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 SMART SM01403 7 101 4.2E-57 T 28-03-2018 IPR027486 Ribosomal protein S10 domain AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.768 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.6E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18285 0b5394559d2e2baf4a55a5eb3b570548 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.6E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 Pfam PF02481 DNA recombination-mediator protein A 87 296 1.2E-77 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 Gene3D G3DSA:3.30.70.260 12 99 9.3E-4 T 28-03-2018 AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 85 305 3.4E-77 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 Gene3D G3DSA:1.10.10.10 289 384 9.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 Gene3D G3DSA:3.40.50.450 129 284 5.2E-38 T 28-03-2018 AFA_RS01135 4988630adc3f9695fb55090c8796f3a4 388 SUPERFAMILY SSF102405 96 305 6.26E-42 T 28-03-2018 AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 SUPERFAMILY SSF46785 150 224 3.59E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 Gene3D G3DSA:2.60.120.10 5 151 3.6E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 SMART SM00100 13 134 5.6E-4 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 SUPERFAMILY SSF51206 11 140 3.4E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 Pfam PF13545 Crp-like helix-turn-helix domain 151 222 1.1E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 Pfam PF00027 Cyclic nucleotide-binding domain 33 118 3.8E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS01080 0d877c592542848d1cb4a34a0e4e23fc 228 Gene3D G3DSA:1.10.10.10 152 223 9.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02100 903a0d7f2106465a52a35c4a1ca0193b 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 422 9.0E-124 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS02100 903a0d7f2106465a52a35c4a1ca0193b 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 417 2.5E-106 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS02100 903a0d7f2106465a52a35c4a1ca0193b 430 PIRSF PIRSF006066 2 429 4.1E-131 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS03490 0f36acd8d3668304612c70678fb46ba4 170 SUPERFAMILY SSF50475 8 163 7.36E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS03490 0f36acd8d3668304612c70678fb46ba4 170 SMART SM00903 17 165 1.1E-48 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS03490 0f36acd8d3668304612c70678fb46ba4 170 Gene3D G3DSA:2.30.110.10 5 167 2.7E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS03490 0f36acd8d3668304612c70678fb46ba4 170 Pfam PF01613 Flavin reductase like domain 18 163 1.3E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS17850 444ab948103a890bee653b033d325038 182 Pfam PF00210 Ferritin-like domain 44 181 3.5E-28 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFA_RS17850 444ab948103a890bee653b033d325038 182 PRINTS PR00601 Bacterioferritin signature 80 100 5.8E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS17850 444ab948103a890bee653b033d325038 182 PRINTS PR00601 Bacterioferritin signature 39 58 5.8E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS17850 444ab948103a890bee653b033d325038 182 PRINTS PR00601 Bacterioferritin signature 170 182 5.8E-7 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS17850 444ab948103a890bee653b033d325038 182 PIRSF PIRSF018063 19 182 7.5E-56 T 28-03-2018 IPR014490 DNA-binding protein from starved cells-like AFA_RS17850 444ab948103a890bee653b033d325038 182 Gene3D G3DSA:1.20.1260.10 10 181 1.8E-45 T 28-03-2018 IPR012347 Ferritin-related AFA_RS17850 444ab948103a890bee653b033d325038 182 SUPERFAMILY SSF47240 39 181 6.69E-40 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS10700 a2025efbfe79146bda3539627323df17 577 Pfam PF06213 Cobalamin biosynthesis protein CobT 19 233 9.9E-19 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFA_RS10700 a2025efbfe79146bda3539627323df17 577 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 364 548 1.4E-40 T 28-03-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFA_RS10700 a2025efbfe79146bda3539627323df17 577 SUPERFAMILY SSF53300 436 545 2.78E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS10700 a2025efbfe79146bda3539627323df17 577 SUPERFAMILY SSF53300 365 407 2.78E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS10700 a2025efbfe79146bda3539627323df17 577 Gene3D G3DSA:3.40.50.410 359 562 2.5E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS10700 a2025efbfe79146bda3539627323df17 577 PIRSF PIRSF031715 242 557 1.7E-73 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFA_RS10700 a2025efbfe79146bda3539627323df17 577 PIRSF PIRSF031715 1 236 3.0E-16 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SUPERFAMILY SSF55785 386 514 2.09E-10 T 28-03-2018 IPR000014 PAS domain AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SUPERFAMILY SSF55874 587 759 1.15E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Gene3D G3DSA:3.30.450.20 380 519 4.7E-16 T 28-03-2018 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SMART SM00388 524 596 2.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Gene3D G3DSA:3.30.565.10 596 769 2.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SMART SM00387 645 763 2.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 712 722 4.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 708 4.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 723 741 4.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SUPERFAMILY SSF47384 522 595 1.37E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 645 757 3.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Pfam PF00512 His Kinase A (phospho-acceptor) domain 526 593 1.3E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SUPERFAMILY SSF158472 328 377 1.44E-7 T 28-03-2018 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Gene3D G3DSA:1.10.287.130 520 592 2.1E-10 T 28-03-2018 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 SMART SM00304 328 380 5.4E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 Pfam PF00672 HAMP domain 328 376 5.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS16480 3ed285553d57d386411c2db9a6160296 779 PIRSF PIRSF037532 1 766 2.6E-221 T 28-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Pfam PF00501 AMP-binding enzyme 99 536 5.5E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 35 90 3.3E-19 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 12 661 50.79 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Gene3D G3DSA:3.40.50.980 276 441 3.1E-37 T 28-03-2018 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 545 626 3.3E-28 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 31 659 1.1E-289 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Gene3D G3DSA:3.40.50.980 83 275 2.8E-45 T 28-03-2018 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Gene3D G3DSA:3.30.300.30 530 644 6.1E-27 T 28-03-2018 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 SUPERFAMILY SSF56801 26 655 3.14E-170 T 28-03-2018 AFA_RS12950 9c7df087aa1858ecef3140af08270112 661 Gene3D G3DSA:2.30.38.10 442 529 1.1E-14 T 28-03-2018 AFA_RS17805 8d1ae34efdf2d7ebdd8b33c5cc0a2557 159 Pfam PF03928 Haem-degrading 8 137 2.2E-26 T 28-03-2018 IPR005624 Haem-degrading AFA_RS17805 8d1ae34efdf2d7ebdd8b33c5cc0a2557 159 SUPERFAMILY SSF143744 4 140 2.22E-34 T 28-03-2018 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.6E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 Gene3D G3DSA:3.40.190.10 178 264 2.0E-19 T 28-03-2018 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 Gene3D G3DSA:3.40.190.10 90 177 1.8E-24 T 28-03-2018 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 Pfam PF03466 LysR substrate binding domain 91 290 6.1E-39 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.3E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 SUPERFAMILY SSF53850 92 295 3.38E-39 T 28-03-2018 AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 SUPERFAMILY SSF46785 1 111 1.01E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01660 1c920348d0454bbbb68b7a18781ac83b 302 Gene3D G3DSA:1.10.10.10 1 87 6.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 SUPERFAMILY SSF46689 211 252 1.57E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 Gene3D G3DSA:1.10.10.60 103 205 1.4E-9 T 28-03-2018 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 SMART SM00342 170 252 1.7E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 Gene3D G3DSA:2.60.120.10 6 102 9.3E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 Pfam PF02311 AraC-like ligand binding domain 25 93 1.0E-4 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 Gene3D G3DSA:1.10.10.60 206 254 2.4E-8 T 28-03-2018 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 SUPERFAMILY SSF46689 170 205 3.05E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 252 9.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 221 236 9.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 SUPERFAMILY SSF51182 11 178 4.77E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS07585 030493425987c2a357e135d6f278f5d9 255 Pfam PF12833 Helix-turn-helix domain 176 252 4.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 Gene3D G3DSA:1.10.10.10 3 92 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 Gene3D G3DSA:3.40.190.10 178 268 4.5E-20 T 28-03-2018 AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 SUPERFAMILY SSF46785 2 113 9.76E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 Pfam PF03466 LysR substrate binding domain 89 293 9.8E-42 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 Gene3D G3DSA:3.40.190.10 93 177 2.8E-21 T 28-03-2018 AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 SUPERFAMILY SSF53850 90 293 1.41E-43 T 28-03-2018 AFA_RS00810 5366e9671dccb5e41482605cc18e563b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 2.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 SUPERFAMILY SSF82689 219 322 8.11E-21 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 Gene3D G3DSA:2.30.30.60 166 218 2.9E-15 T 28-03-2018 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 Gene3D G3DSA:3.30.70.100 219 317 4.5E-20 T 28-03-2018 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 182 216 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 Pfam PF00924 Mechanosensitive ion channel 109 311 1.0E-58 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 SUPERFAMILY SSF82861 66 148 3.27E-10 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFA_RS06175 1892e5bdac2cc5b9f695cd0cdd9c7a97 334 SUPERFAMILY SSF50182 150 216 3.2E-16 T 28-03-2018 IPR010920 LSM domain AFA_RS05820 18fc68172ce39f0b2a849c38933b0f5c 138 Pfam PF00460 Flagella basal body rod protein 13 39 3.1E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS05820 18fc68172ce39f0b2a849c38933b0f5c 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site AFA_RS05820 18fc68172ce39f0b2a849c38933b0f5c 138 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 8 137 5.3E-36 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFA_RS05820 18fc68172ce39f0b2a849c38933b0f5c 138 PIRSF PIRSF002889 1 138 1.3E-41 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 SUPERFAMILY SSF55124 6 138 5.23E-26 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 163 323 2.0E-51 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 7.5E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 PRINTS PR00397 Sirohaem Fe-binding site signature 473 491 7.5E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 10 554 4.6E-245 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 71 129 2.7E-9 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 347 410 4.5E-14 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 473 489 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 SUPERFAMILY SSF55124 340 415 4.74E-19 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 SUPERFAMILY SSF56014 422 553 2.88E-30 T 28-03-2018 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Gene3D G3DSA:3.30.413.10 423 555 1.6E-20 T 28-03-2018 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Gene3D G3DSA:3.30.413.10 132 340 4.1E-52 T 28-03-2018 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 1 567 54.249 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18185 3877dfdd1824bf9c8c34064d3c78dd74 569 SUPERFAMILY SSF56014 139 338 7.59E-55 T 28-03-2018 AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 SUPERFAMILY SSF54826 1 127 8.55E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 Gene3D G3DSA:3.20.20.120 131 365 1.2E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 SMART SM00922 142 252 6.1E-13 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 98 123 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 123 5.0E-20 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 SUPERFAMILY SSF51604 111 373 2.72E-56 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 Gene3D G3DSA:3.30.390.10 1 130 1.5E-39 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS02330 cb0ad7977ae2d66e7b04170ac4a17d49 384 Pfam PF13378 Enolase C-terminal domain-like 147 365 6.5E-44 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 Pfam PF13847 Methyltransferase domain 122 263 6.5E-16 T 28-03-2018 IPR025714 Methyltransferase domain AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 Gene3D G3DSA:1.10.8.10 18 91 5.3E-16 T 28-03-2018 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 37 284 2.1E-83 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 Gene3D G3DSA:3.40.50.150 92 287 1.9E-41 T 28-03-2018 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 SUPERFAMILY SSF53335 24 285 3.44E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 15 288 40.642 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 193 199 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 126 140 6.9E-5 T 28-03-2018 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 190 202 6.9E-5 T 28-03-2018 AFA_RS16670 0ecb84ed8d3604e6123414270049a04b 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 32 285 4.7E-71 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 Gene3D G3DSA:3.40.50.300 5 274 2.2E-65 T 28-03-2018 AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 Pfam PF00005 ABC transporter 33 179 2.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 SMART SM00382 40 227 5.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 Pfam PF02687 FtsX-like permease family 559 640 9.6E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 Pfam PF12704 MacB-like periplasmic core domain 278 496 5.2E-33 T 28-03-2018 IPR025857 MacB-like periplasmic core domain AFA_RS04410 88bc3841a7da27e14af219fafd9e9f7d 652 SUPERFAMILY SSF52540 8 238 1.56E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 SUPERFAMILY SSF50447 692 774 4.78E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 SUPERFAMILY SSF46955 4 51 2.56E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:3.40.50.300 514 683 3.7E-41 T 28-03-2018 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Pfam PF00009 Elongation factor Tu GTP binding domain 524 679 1.6E-35 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 SUPERFAMILY SSF50447 920 1016 5.2E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:3.30.56.50 445 486 2.4E-10 T 28-03-2018 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:3.30.56.50 5 46 1.7E-11 T 28-03-2018 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 523 678 3.7E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 SUPERFAMILY SSF52156 797 925 4.71E-36 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:2.40.30.10 919 1017 5.5E-27 T 28-03-2018 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 442 493 1.1E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 4.1E-9 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 436 1018 2.3E-254 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:3.40.50.10050 816 897 1.5E-26 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 SUPERFAMILY SSF52540 514 688 9.57E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1016 17.365 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 ProSitePatterns PS01176 Initiation factor 2 signature. 969 991 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Gene3D G3DSA:2.40.30.10 684 785 1.6E-16 T 28-03-2018 AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 97 6.8E-14 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial AFA_RS05100 e83ca357ef509040793cd7ade93e5261 1018 Pfam PF11987 Translation-initiation factor 2 805 908 1.8E-35 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:3.30.2090.10 181 269 9.6E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 40 133 5.23E-22 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 556 651 7.06E-15 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:1.20.1640.10 807 1026 2.5E-34 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:1.20.1640.10 281 501 1.1E-46 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:3.30.70.1430 558 657 1.4E-11 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Pfam PF00873 AcrB/AcrD/AcrF family 3 1013 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:3.30.70.1430 40 142 3.2E-22 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82714 183 265 2.62E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16065 5a713844804357061ac04883f062e741 1028 Gene3D G3DSA:3.30.2090.10 708 793 2.2E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 2.6E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 665 706 5.23E-8 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 793 843 5.23E-8 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 136 182 1.07E-23 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82693 268 324 1.07E-23 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82866 290 490 2.75E-46 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82866 816 1015 9.02E-44 T 28-03-2018 AFA_RS16065 5a713844804357061ac04883f062e741 1028 SUPERFAMILY SSF82714 708 791 2.35E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.1E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 659 739 1.6E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Gene3D G3DSA:1.10.8.60 357 444 1.6E-29 T 28-03-2018 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SUPERFAMILY SSF81923 1 143 6.8E-54 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 2 740 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Gene3D G3DSA:1.10.1780.10 1 144 2.6E-22 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SMART SM00382 493 660 5.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SMART SM00382 212 358 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 308 320 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Gene3D G3DSA:3.40.50.300 173 356 4.6E-26 T 28-03-2018 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SUPERFAMILY SSF52540 176 425 4.77E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 217 330 1.3E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Gene3D G3DSA:3.40.50.300 448 658 6.2E-43 T 28-03-2018 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Pfam PF07724 AAA domain (Cdc48 subfamily) 492 653 5.4E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SMART SM01086 659 749 1.2E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 SUPERFAMILY SSF52540 443 744 3.84E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 615 5.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 568 586 5.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 539 557 5.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 497 515 5.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 524 542 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 AFA_RS07415 c56f82a3c9f31c2d3e33e07e77bb7fd3 773 Gene3D G3DSA:1.10.8.60 659 761 9.1E-22 T 28-03-2018 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 256 6.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 240 6.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 Gene3D G3DSA:1.10.10.60 213 261 1.6E-10 T 28-03-2018 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 Gene3D G3DSA:1.10.10.60 140 212 1.0E-11 T 28-03-2018 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 SMART SM00342 174 256 1.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 Pfam PF12833 Helix-turn-helix domain 181 257 6.8E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 SUPERFAMILY SSF51182 19 181 1.25E-11 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 Pfam PF02311 AraC-like ligand binding domain 28 118 4.3E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 Gene3D G3DSA:2.60.120.10 8 98 1.7E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02850 50bbf4bcedda540cd3158153151fb9ed 265 SUPERFAMILY SSF46689 221 257 1.61E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS15430 40ac2ecc6beae29faa7a3cffcaeb9958 135 SUPERFAMILY SSF101756 34 133 2.35E-23 T 28-03-2018 IPR005220 Bacterial OB-fold AFA_RS15430 40ac2ecc6beae29faa7a3cffcaeb9958 135 Pfam PF04076 Bacterial OB fold (BOF) protein 32 131 4.1E-20 T 28-03-2018 IPR005220 Bacterial OB-fold AFA_RS15430 40ac2ecc6beae29faa7a3cffcaeb9958 135 Gene3D G3DSA:2.40.50.200 22 135 1.2E-22 T 28-03-2018 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 SUPERFAMILY SSF52343 591 727 3.67E-32 T 28-03-2018 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Pfam PF00970 Oxidoreductase FAD-binding domain 506 577 6.1E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Gene3D G3DSA:3.40.50.80 584 726 2.4E-27 T 28-03-2018 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Gene3D G3DSA:3.40.50.360 327 479 9.1E-21 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Pfam PF00258 Flavodoxin 337 455 1.4E-13 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 SUPERFAMILY SSF52218 333 480 9.26E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Pfam PF03929 PepSY-associated TM region 6 316 3.3E-37 T 28-03-2018 IPR005625 PepSY-associated TM protein AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Pfam PF00175 Oxidoreductase NAD-binding domain 597 699 5.5E-13 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 SUPERFAMILY SSF63380 486 588 3.4E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 Gene3D G3DSA:2.40.30.10 480 580 2.5E-17 T 28-03-2018 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 596 615 5.7E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 538 545 5.7E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 631 642 5.7E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS03940 15d1ce524dadc8fca1743bfdc5346268 727 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 520 530 5.7E-10 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS12245 e5c1222679ee7e0c9b10704338f49aad 87 Gene3D G3DSA:1.10.1220.10 43 82 4.3E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS12245 e5c1222679ee7e0c9b10704338f49aad 87 Pfam PF12441 CopG antitoxin of type II toxin-antitoxin system 6 81 8.9E-26 T 28-03-2018 IPR022148 CopG antitoxin AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 SUPERFAMILY SSF51905 344 397 3.29E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 SUPERFAMILY SSF51905 5 244 3.29E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 7 406 4.2E-147 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 Pfam PF00890 FAD binding domain 10 380 2.2E-93 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 Gene3D G3DSA:3.50.50.60 2 290 1.2E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.0E-8 T 28-03-2018 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 343 365 2.0E-8 T 28-03-2018 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 SUPERFAMILY SSF46977 519 591 1.7E-12 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 Gene3D G3DSA:3.50.50.60 297 396 2.6E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 Gene3D G3DSA:1.20.58.100 500 591 1.5E-12 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS08395 5e95dcc86ba846604bfa717c7b62bd8a 591 SUPERFAMILY SSF56425 227 340 4.34E-38 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 279 1.6E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 384 547 6.5E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 SUPERFAMILY SSF161098 14 277 9.25E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 SUPERFAMILY SSF161098 297 548 4.03E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 Gene3D G3DSA:1.10.3720.10 13 284 2.3E-37 T 28-03-2018 AFA_RS04625 05b66985786d0d21f9d43f38b787c52d 555 Gene3D G3DSA:1.10.3720.10 297 549 3.5E-29 T 28-03-2018 AFA_RS00785 b5cd1442d5079e02fbbd688fc78bf80a 403 Gene3D G3DSA:3.40.50.10540 6 403 3.3E-143 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS00785 b5cd1442d5079e02fbbd688fc78bf80a 403 Pfam PF02515 CoA-transferase family III 11 379 1.7E-125 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS00785 b5cd1442d5079e02fbbd688fc78bf80a 403 SUPERFAMILY SSF89796 9 402 4.19E-133 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 PIRSF PIRSF002599 1 69 6.0E-20 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 PRINTS PR00050 Cold shock protein signature 27 36 1.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 PRINTS PR00050 Cold shock protein signature 6 21 1.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 PRINTS PR00050 Cold shock protein signature 42 60 1.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 SMART SM00357 5 69 5.2E-22 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 Gene3D G3DSA:2.40.50.140 2 69 5.4E-24 T 28-03-2018 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 67 1.8E-25 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 SUPERFAMILY SSF50249 4 68 1.56E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS06250 777548f32bf80f78fb149873f66b7f3b 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS10215 c586387e961b131b48a384e49299650c 267 Gene3D G3DSA:3.90.230.10 1 259 8.6E-84 T 28-03-2018 AFA_RS10215 c586387e961b131b48a384e49299650c 267 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 171 189 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 Hamap MF_01974 Methionine aminopeptidase [map]. 3 254 40.127 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 Pfam PF00557 Metallopeptidase family M24 12 245 4.5E-53 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS10215 c586387e961b131b48a384e49299650c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.3E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.3E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.3E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.3E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 252 2.1E-93 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS10215 c586387e961b131b48a384e49299650c 267 SUPERFAMILY SSF55920 4 252 6.54E-88 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 SUPERFAMILY SSF52738 157 344 5.75E-73 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 SMART SM00448 4 116 8.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 Gene3D G3DSA:3.40.50.2300 1 140 7.2E-28 T 28-03-2018 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 Pfam PF00072 Response regulator receiver domain 6 108 2.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 PIRSF PIRSF000876 1 349 4.3E-133 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 Gene3D G3DSA:3.40.50.180 151 348 2.3E-77 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 SUPERFAMILY SSF52172 1 108 1.18E-28 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 346 40.722 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFA_RS05765 6231b071a9f3884eb38cba0207ef3814 352 Pfam PF01339 CheB methylesterase 162 341 8.9E-61 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFA_RS16510 fc2000e256e9643ef19802c4ddfc7a73 253 PIRSF PIRSF015736 1 251 1.0E-61 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase AFA_RS16510 fc2000e256e9643ef19802c4ddfc7a73 253 Gene3D G3DSA:3.40.50.2300 113 236 9.6E-7 T 28-03-2018 AFA_RS16510 fc2000e256e9643ef19802c4ddfc7a73 253 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 226 3.4E-8 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS16510 fc2000e256e9643ef19802c4ddfc7a73 253 Hamap MF_00943 Maleate isomerase [maiA]. 4 250 50.945 T 28-03-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 AFA_RS05995 639fab3f8626381f2c31f8a3a72da736 107 Gene3D G3DSA:3.30.160.170 5 103 9.6E-17 T 28-03-2018 IPR005186 FlaG protein AFA_RS05995 639fab3f8626381f2c31f8a3a72da736 107 Pfam PF03646 FlaG protein 18 103 1.2E-16 T 28-03-2018 IPR005186 FlaG protein AFA_RS05995 639fab3f8626381f2c31f8a3a72da736 107 SUPERFAMILY SSF160214 15 104 8.63E-19 T 28-03-2018 IPR005186 FlaG protein AFA_RS18450 1c0f955d22ed3256652f6fc03dc0f394 305 SUPERFAMILY SSF53686 4 298 1.31E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS18450 1c0f955d22ed3256652f6fc03dc0f394 305 Gene3D G3DSA:3.40.50.1100 141 304 3.9E-34 T 28-03-2018 AFA_RS18450 1c0f955d22ed3256652f6fc03dc0f394 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 289 1.1E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS18450 1c0f955d22ed3256652f6fc03dc0f394 305 Gene3D G3DSA:3.40.50.1100 4 140 9.2E-34 T 28-03-2018 AFA_RS18450 1c0f955d22ed3256652f6fc03dc0f394 305 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 28 41 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 SUPERFAMILY SSF46785 1 84 1.75E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 Gene3D G3DSA:1.10.10.10 1 83 5.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 Gene3D G3DSA:3.40.190.10 177 266 3.3E-15 T 28-03-2018 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 Pfam PF03466 LysR substrate binding domain 89 275 7.7E-35 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 SUPERFAMILY SSF53850 90 287 1.45E-30 T 28-03-2018 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 Gene3D G3DSA:3.40.190.10 88 176 5.2E-18 T 28-03-2018 AFA_RS08235 699cb58429645a1b2dd312acb325a6fe 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14945 406e84bfaacfe672f3801ce34af2d4c8 1099 SMART SM00869 815 1089 5.7E-27 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS14945 406e84bfaacfe672f3801ce34af2d4c8 1099 SUPERFAMILY SSF103515 781 1099 1.83E-41 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS14945 406e84bfaacfe672f3801ce34af2d4c8 1099 Gene3D G3DSA:2.40.128.130 770 1099 2.6E-41 T 28-03-2018 AFA_RS14945 406e84bfaacfe672f3801ce34af2d4c8 1099 Pfam PF03797 Autotransporter beta-domain 822 1077 4.4E-40 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS03805 76cd85b100a669c8c2cf72505ff0a85d 775 Pfam PF04453 Organic solvent tolerance protein 275 649 1.1E-75 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 AFA_RS03805 76cd85b100a669c8c2cf72505ff0a85d 775 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 5 742 19.955 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 AFA_RS03805 76cd85b100a669c8c2cf72505ff0a85d 775 Gene3D G3DSA:2.60.450.10 28 180 2.7E-10 T 28-03-2018 AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 SUPERFAMILY SSF52833 12 103 2.11E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 Gene3D G3DSA:3.40.30.10 19 112 8.7E-23 T 28-03-2018 AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 Gene3D G3DSA:1.20.1050.10 113 156 4.8E-11 T 28-03-2018 AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 Gene3D G3DSA:1.20.1050.10 157 227 3.9E-16 T 28-03-2018 AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 Pfam PF14497 Glutathione S-transferase, C-terminal domain 148 226 4.9E-10 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 SUPERFAMILY SSF47616 109 233 3.34E-31 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS11400 d84005a345039c221e52fcf07bc6d777 235 Pfam PF02798 Glutathione S-transferase, N-terminal domain 22 100 3.7E-10 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 SUPERFAMILY SSF46689 23 81 2.62E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 8.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 Gene3D G3DSA:1.10.10.60 63 168 3.0E-7 T 28-03-2018 AFA_RS04965 9607341b6d85b6c1557a6f7e6fba2db5 227 Gene3D G3DSA:1.10.10.60 7 62 1.4E-14 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 424 4.2E-134 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 Pfam PF00344 SecY translocase 74 412 3.5E-118 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 428 29.628 T 28-03-2018 IPR026593 Protein translocase subunit SecY AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 4.5E-94 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 PIRSF PIRSF004557 2 436 2.1E-127 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 Gene3D G3DSA:1.10.3370.10 7 434 3.4E-162 T 28-03-2018 AFA_RS18000 821e82eb46df3fa4bcd947b225eade88 441 SUPERFAMILY SSF103491 13 419 2.09E-132 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 Pfam PF00239 Resolvase, N terminal domain 14 166 2.6E-23 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 Pfam PF02796 Helix-turn-helix domain of resolvase 173 209 3.1E-5 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 ProSitePatterns PS00397 Site-specific recombinases active site. 16 24 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 Gene3D G3DSA:1.10.10.60 168 210 2.6E-5 T 28-03-2018 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 SUPERFAMILY SSF53041 11 166 3.27E-27 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 Gene3D G3DSA:3.40.50.1390 7 167 2.1E-35 T 28-03-2018 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 ProSitePatterns PS00398 Site-specific recombinases signature 2. 71 83 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS07920 58d93e5e36b01ec54cac8f31f4a23bca 245 SMART SM00857 13 166 3.5E-31 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 SUPERFAMILY SSF46894 120 216 9.35E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 SMART SM00862 145 216 3.3E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 Gene3D G3DSA:3.40.50.2300 1 119 1.7E-27 T 28-03-2018 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 SMART SM00448 1 112 6.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 SUPERFAMILY SSF52172 1 124 1.99E-32 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 7.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS06375 a41956d3b25bcb1a3471b2b6a1a02354 220 Gene3D G3DSA:1.10.10.10 120 219 8.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 Gene3D G3DSA:1.10.10.60 1 48 4.6E-20 T 28-03-2018 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 Gene3D G3DSA:1.10.10.60 49 69 9.2E-12 T 28-03-2018 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 Gene3D G3DSA:1.10.357.10 70 195 1.0E-15 T 28-03-2018 AFA_RS03870 502d6b187c5d6dac041ed308156b7dd2 195 SUPERFAMILY SSF46689 2 86 2.41E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 190 2.9E-55 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 Gene3D G3DSA:3.40.50.1470 1 198 8.9E-65 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 Pfam PF01195 Peptidyl-tRNA hydrolase 7 191 6.3E-54 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 SUPERFAMILY SSF53178 5 192 1.19E-62 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFA_RS02820 102ca864ad92c8b7cb381148c7b860e7 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 186 33.616 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 SUPERFAMILY SSF103473 5 396 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 Gene3D G3DSA:1.20.1250.20 3 201 2.7E-38 T 28-03-2018 AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 83 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 ProSitePatterns PS00217 Sugar transport proteins signature 2. 109 134 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 Gene3D G3DSA:1.20.1250.20 204 405 2.8E-24 T 28-03-2018 AFA_RS13955 639683c415d532eba4f2815b7258ca65 414 Pfam PF07690 Major Facilitator Superfamily 18 331 3.8E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS11595 ee03d8a845c356d522dc1f2fb61ac317 282 SUPERFAMILY SSF53335 25 248 3.75E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS11595 ee03d8a845c356d522dc1f2fb61ac317 282 Gene3D G3DSA:3.40.50.150 1 184 3.1E-25 T 28-03-2018 AFA_RS11595 ee03d8a845c356d522dc1f2fb61ac317 282 Pfam PF13847 Methyltransferase domain 53 158 4.7E-13 T 28-03-2018 IPR025714 Methyltransferase domain AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF04546 Sigma-70, non-essential region 277 474 3.8E-60 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Gene3D G3DSA:1.10.10.10 667 738 4.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 SUPERFAMILY SSF88946 253 572 7.53E-96 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 501 737 1.3E-118 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF04542 Sigma-70 region 2 507 574 8.3E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Gene3D G3DSA:1.10.601.10 1 252 1.6E-17 T 28-03-2018 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Gene3D G3DSA:1.10.601.10 253 574 9.6E-97 T 28-03-2018 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 698 724 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 PRINTS PR00046 Major sigma-70 factor signature 529 542 7.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 PRINTS PR00046 Major sigma-70 factor signature 553 561 7.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 PRINTS PR00046 Major sigma-70 factor signature 698 713 7.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 PRINTS PR00046 Major sigma-70 factor signature 713 724 7.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 PRINTS PR00046 Major sigma-70 factor signature 677 689 7.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF04539 Sigma-70 region 3 584 660 4.8E-25 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Gene3D G3DSA:1.10.10.10 575 625 8.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF00140 Sigma-70 factor, region 1.2 236 268 4.6E-14 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 SUPERFAMILY SSF88659 635 736 2.43E-27 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 501 726 1.5E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 529 542 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 SUPERFAMILY SSF88659 578 652 4.71E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 132 738 41.58 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF03979 Sigma-70 factor, region 1.1 140 219 2.4E-28 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 AFA_RS11495 da88aa0f7048252095b0136f7987e88b 740 Pfam PF04545 Sigma-70, region 4 673 726 7.5E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS14625 b499ca9bf500b0e5aba6e0a0897339bb 373 TIGRFAM TIGR02794 tolA_full: protein TolA 23 360 7.4E-55 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 AFA_RS14625 b499ca9bf500b0e5aba6e0a0897339bb 373 Gene3D G3DSA:3.30.1150.10 270 368 5.7E-14 T 28-03-2018 AFA_RS14625 b499ca9bf500b0e5aba6e0a0897339bb 373 Pfam PF13103 TonB C terminal 284 360 8.8E-12 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 AFA_RS14625 b499ca9bf500b0e5aba6e0a0897339bb 373 SUPERFAMILY SSF74653 283 364 5.23E-11 T 28-03-2018 AFA_RS14625 b499ca9bf500b0e5aba6e0a0897339bb 373 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 311 362 2.4E-8 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Gene3D G3DSA:1.10.860.10 513 658 4.2E-17 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFA_RS11500 d632866bfd66024e718141ec04277340 668 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 247 8.8E-36 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal AFA_RS11500 d632866bfd66024e718141ec04277340 668 Gene3D G3DSA:3.40.1360.20 252 366 1.6E-31 T 28-03-2018 AFA_RS11500 d632866bfd66024e718141ec04277340 668 PIRSF PIRSF002811 1 666 6.4E-137 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Gene3D G3DSA:3.90.580.10 1 100 5.1E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFA_RS11500 d632866bfd66024e718141ec04277340 668 SUPERFAMILY SSF56731 119 416 4.32E-97 T 28-03-2018 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Gene3D G3DSA:1.20.50.20 367 414 2.7E-12 T 28-03-2018 AFA_RS11500 d632866bfd66024e718141ec04277340 668 SUPERFAMILY SSF117023 530 654 1.31E-10 T 28-03-2018 AFA_RS11500 d632866bfd66024e718141ec04277340 668 SMART SM00766 529 653 2.1E-11 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Pfam PF08278 DNA primase DnaG DnaB-binding 531 652 1.1E-13 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Pfam PF13662 Toprim domain 257 322 1.5E-15 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS11500 d632866bfd66024e718141ec04277340 668 TIGRFAM TIGR01391 dnaG: DNA primase 2 414 1.1E-135 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Gene3D G3DSA:3.90.980.10 110 237 1.3E-37 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal AFA_RS11500 d632866bfd66024e718141ec04277340 668 SMART SM00400 33 87 6.2E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Pfam PF10410 DnaB-helicase binding domain of primase 366 415 5.1E-7 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 AFA_RS11500 d632866bfd66024e718141ec04277340 668 SUPERFAMILY SSF57783 2 97 1.6E-35 T 28-03-2018 AFA_RS11500 d632866bfd66024e718141ec04277340 668 SMART SM00493 256 327 1.4E-18 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS11500 d632866bfd66024e718141ec04277340 668 Pfam PF01807 CHC2 zinc finger 3 96 1.4E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFA_RS11500 d632866bfd66024e718141ec04277340 668 Hamap MF_00974 DNA primase [dnaG]. 1 653 27.132 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF48452 58 93 6.07E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF48452 150 270 6.07E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SMART SM01043 116 255 8.2E-17 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Pfam PF03704 Bacterial transcriptional activator domain 126 250 2.9E-16 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:1.10.10.10 9 107 6.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:1.25.40.10 753 962 1.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF48452 838 859 1.41E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF48452 1120 1188 1.41E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF48452 951 1032 1.41E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Pfam PF13191 AAA ATPase domain 449 625 7.8E-19 T 28-03-2018 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF52540 592 696 1.2E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 SUPERFAMILY SSF52540 447 529 1.2E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:1.25.40.10 1121 1209 2.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:3.40.50.300 447 752 4.5E-8 T 28-03-2018 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:1.25.40.10 161 364 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS09885 55c830101e903b04d5c608f555fc121e 1211 Gene3D G3DSA:1.25.40.10 963 1110 3.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 SUPERFAMILY SSF56935 133 844 1.31E-131 T 28-03-2018 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 SMART SM00965 72 122 5.6E-13 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 827 844 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 Pfam PF07660 Secretin and TonB N terminus short domain 74 121 4.0E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 Pfam PF00593 TonB dependent receptor 382 841 4.2E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 Gene3D G3DSA:2.40.170.20 287 844 6.1E-77 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 Gene3D G3DSA:2.170.130.10 124 281 1.2E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 Pfam PF07715 TonB-dependent Receptor Plug Domain 167 273 3.6E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS00450 81bbae7336ce06b7a48de685f5a4b1e2 844 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 169 844 1.2E-108 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 Pfam PF07687 Peptidase dimerisation domain 173 276 1.4E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 Pfam PF01546 Peptidase family M20/M25/M40 73 385 9.2E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 SUPERFAMILY SSF53187 14 176 1.6E-51 T 28-03-2018 AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 SUPERFAMILY SSF53187 307 390 1.6E-51 T 28-03-2018 AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 SUPERFAMILY SSF55031 178 277 2.09E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS08930 3ebd27bc1b404c67f1abc554606bf652 393 Gene3D G3DSA:3.40.630.10 6 277 5.8E-54 T 28-03-2018 AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 SMART SM00895 96 221 9.8E-9 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 SUPERFAMILY SSF48008 95 226 4.97E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 Gene3D G3DSA:1.10.10.10 1 81 2.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 Pfam PF07729 FCD domain 96 217 9.0E-17 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 SUPERFAMILY SSF46785 21 90 1.47E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 86 4.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 Gene3D G3DSA:1.20.120.530 82 227 2.1E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS17320 326e9ef0398a526bd51de99d4293e748 230 SMART SM00345 28 86 4.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 SMART SM00852 18 168 9.4E-24 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 Gene3D G3DSA:3.40.980.10 10 203 1.7E-40 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 79 92 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 160 1.9E-36 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 SUPERFAMILY SSF53218 15 203 6.54E-44 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03420 565706e00bbfdfe5c1ee8906a7f68020 209 Pfam PF00994 Probable molybdopterin binding domain 19 160 4.1E-30 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Gene3D G3DSA:1.10.8.60 316 408 1.3E-31 T 28-03-2018 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 411 6.4E-200 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 SUPERFAMILY SSF52540 63 401 2.16E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Gene3D G3DSA:3.40.50.300 56 314 9.2E-70 T 28-03-2018 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 SMART SM00994 11 51 3.8E-22 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Pfam PF06689 ClpX C4-type zinc finger 12 49 8.9E-19 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 SUPERFAMILY SSF57716 12 48 7.84E-10 T 28-03-2018 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 414 52.6 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 394 8.4E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 309 9.5E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 SMART SM00382 112 332 4.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07675 f40e099f05fe8efa3c8bb501f063bcb4 433 SMART SM01086 316 411 3.1E-31 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 SUPERFAMILY SSF53623 91 311 9.16E-72 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Pfam PF08245 Mur ligase middle domain 110 294 1.4E-26 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Gene3D G3DSA:3.40.50.720 1 93 1.2E-13 T 28-03-2018 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 SUPERFAMILY SSF53244 313 463 7.63E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Gene3D G3DSA:3.90.190.20 315 468 1.6E-37 T 28-03-2018 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 405 7.9E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 463 7.9E-167 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 SUPERFAMILY SSF51984 6 92 2.22E-27 T 28-03-2018 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Pfam PF01225 Mur ligase family, catalytic domain 7 105 1.1E-26 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 42.44 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03670 e9a43f2868f1437a3dde831e3a9f15d5 468 Gene3D G3DSA:3.40.1190.10 94 314 1.7E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS01245 102659013ca33321f48e7a162bd3c5a6 263 Gene3D G3DSA:1.10.12.10 221 263 1.6E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS01245 102659013ca33321f48e7a162bd3c5a6 263 Gene3D G3DSA:3.90.226.10 9 220 8.7E-65 T 28-03-2018 AFA_RS01245 102659013ca33321f48e7a162bd3c5a6 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 262 3.6E-55 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS01245 102659013ca33321f48e7a162bd3c5a6 263 SUPERFAMILY SSF52096 8 262 3.15E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 Pfam PF00925 GTP cyclohydrolase II 225 380 2.9E-31 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 Gene3D G3DSA:3.90.870.10 8 226 7.2E-91 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 213 4.6E-72 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 22 212 4.4E-80 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 SUPERFAMILY SSF55821 17 217 4.35E-84 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 15 217 38.082 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 SUPERFAMILY SSF142695 218 381 8.63E-41 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS14875 2b99d22f82b484a2db91352361958a2b 388 PIRSF PIRSF001259 16 384 2.9E-111 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 SUPERFAMILY SSF46548 2 154 2.88E-40 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 SUPERFAMILY SSF51971 391 483 1.15E-10 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 130 2.4E-26 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Gene3D G3DSA:3.40.50.720 144 251 1.8E-21 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 1.3E-21 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.3E-21 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.3E-21 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 489 2.9E-218 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Gene3D G3DSA:3.50.50.60 337 416 1.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Gene3D G3DSA:3.50.50.60 252 336 3.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Gene3D G3DSA:1.10.1060.10 7 143 4.4E-41 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 330 1.2E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 383 471 2.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 SUPERFAMILY SSF51971 142 416 4.94E-65 T 28-03-2018 AFA_RS01765 d1735d157e69fe1b3e43860990984007 490 Gene3D G3DSA:3.50.50.60 418 490 9.5E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 Gene3D G3DSA:3.40.50.1860 121 269 1.2E-35 T 28-03-2018 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 78 86 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 Gene3D G3DSA:3.40.50.1860 10 120 1.6E-27 T 28-03-2018 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 187 197 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 SUPERFAMILY SSF53681 116 262 9.68E-30 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 Pfam PF01177 Asp/Glu/Hydantoin racemase 14 221 5.2E-30 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 SUPERFAMILY SSF53681 13 114 1.01E-33 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 TIGRFAM TIGR00067 glut_race: glutamate racemase 14 256 5.2E-60 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS14190 dde266847588e4f81b2dd850bfbe27f9 282 Hamap MF_00258 Glutamate racemase [murI]. 12 263 33.147 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 SUPERFAMILY SSF53850 88 294 5.29E-29 T 28-03-2018 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 Gene3D G3DSA:3.40.190.10 86 176 7.9E-15 T 28-03-2018 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 Gene3D G3DSA:3.40.190.10 177 266 7.6E-6 T 28-03-2018 AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 SUPERFAMILY SSF46785 1 109 8.47E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 Gene3D G3DSA:1.10.10.10 1 83 7.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00885 4b915edb92143da92859a1d45c26430e 312 Pfam PF03466 LysR substrate binding domain 86 289 7.2E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 280 725 2.6E-69 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 PRINTS PR00173 Glutamate-aspartate symporter signature 533 558 1.1E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 PRINTS PR00173 Glutamate-aspartate symporter signature 715 734 1.1E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 PRINTS PR00173 Glutamate-aspartate symporter signature 445 465 1.1E-5 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 Gene3D G3DSA:1.20.210.10 270 744 1.2E-68 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS15955 e4a8b8eb3dfa7677e169bd3ca2c507b6 759 SUPERFAMILY SSF81442 275 749 1.44E-79 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 Hamap MF_00328 Guanylate kinase [gmk]. 5 188 35.988 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 Pfam PF00625 Guanylate kinase 10 186 6.7E-47 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 8 185 8.8E-72 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 Gene3D G3DSA:3.40.50.300 85 188 1.1E-30 T 28-03-2018 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 Gene3D G3DSA:3.40.50.300 6 51 1.3E-4 T 28-03-2018 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 SUPERFAMILY SSF52540 5 191 2.51E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 Gene3D G3DSA:3.30.63.10 52 84 2.3E-24 T 28-03-2018 AFA_RS10475 075ff86c7495d6036be0f9fa40567f69 214 SMART SM00072 6 188 1.2E-58 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFA_RS10495 3d6678d181a70be70afc8b48bc9de6fc 227 Pfam PF03591 AzlC protein 17 155 6.2E-38 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease AFA_RS07905 11ae040c5a7a17783c049145e9163d69 168 SUPERFAMILY SSF52788 6 144 7.72E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS07905 11ae040c5a7a17783c049145e9163d69 168 SMART SM00226 6 144 2.1E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS07905 11ae040c5a7a17783c049145e9163d69 168 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 141 3.0E-16 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS07905 11ae040c5a7a17783c049145e9163d69 168 Gene3D G3DSA:3.40.50.2300 2 144 1.6E-34 T 28-03-2018 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 SUPERFAMILY SSF53244 362 501 3.66E-42 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 SUPERFAMILY SSF53623 303 360 5.1E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 SUPERFAMILY SSF53623 129 270 5.1E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Gene3D G3DSA:3.40.1190.10 111 362 1.4E-58 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 132 155 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 13 501 31.576 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Gene3D G3DSA:3.40.50.720 15 110 1.3E-10 T 28-03-2018 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Pfam PF02875 Mur ligase family, glutamate ligase domain 364 433 7.6E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 SUPERFAMILY SSF51984 16 110 7.45E-9 T 28-03-2018 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Gene3D G3DSA:3.90.190.20 367 500 5.8E-40 T 28-03-2018 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 Pfam PF08245 Mur ligase middle domain 134 342 8.6E-26 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03655 93a350d2bce8a7d5ad748e1c2cde5d6c 509 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 499 1.1E-113 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS10030 7d7cce3fdb0ec8b89ab9505a2f3b1aa0 114 Pfam PF03960 ArsC family 5 113 3.1E-15 T 28-03-2018 IPR006660 Arsenate reductase-like AFA_RS10030 7d7cce3fdb0ec8b89ab9505a2f3b1aa0 114 Gene3D G3DSA:3.40.30.10 1 114 1.4E-34 T 28-03-2018 AFA_RS10030 7d7cce3fdb0ec8b89ab9505a2f3b1aa0 114 SUPERFAMILY SSF52833 3 114 1.52E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10030 7d7cce3fdb0ec8b89ab9505a2f3b1aa0 114 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 114 8.3E-46 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 AFA_RS04450 574022648550566019246a4c93bd2f6f 203 SUPERFAMILY SSF53335 7 193 1.4E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS04450 574022648550566019246a4c93bd2f6f 203 Pfam PF13649 Methyltransferase domain 47 136 1.1E-15 T 28-03-2018 AFA_RS04450 574022648550566019246a4c93bd2f6f 203 Gene3D G3DSA:3.40.50.150 1 202 1.6E-33 T 28-03-2018 AFA_RS18425 50c3a71246c23ace64186217bd663fad 389 Gene3D G3DSA:3.90.1150.10 295 389 4.0E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS18425 50c3a71246c23ace64186217bd663fad 389 Pfam PF00155 Aminotransferase class I and II 26 386 1.4E-59 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS18425 50c3a71246c23ace64186217bd663fad 389 SUPERFAMILY SSF53383 3 389 1.16E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS18425 50c3a71246c23ace64186217bd663fad 389 Gene3D G3DSA:3.40.640.10 43 294 5.0E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.30.1330.10 231 438 4.7E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.30.1330.10 639 838 3.8E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.30.1330.10 195 230 0.0023 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF56042 445 680 6.58E-46 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 8 1352 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.90.650.10 845 1045 2.1E-35 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.90.650.10 440 633 2.8E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SMART SM01211 1089 1352 2.6E-133 T 28-03-2018 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1353 20.439 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF82697 4 160 4.13E-39 T 28-03-2018 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF55326 648 841 1.62E-62 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF109736 168 232 1.83E-21 T 28-03-2018 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF52317 1085 1352 5.73E-85 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF55326 233 441 1.26E-56 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 SUPERFAMILY SSF56042 850 1082 5.23E-46 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Gene3D G3DSA:3.40.50.880 1088 1350 1.5E-28 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1089 1352 9.4E-98 T 28-03-2018 AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Pfam PF02769 AIR synthase related protein, C-terminal domain 445 602 1.2E-24 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS07825 27c10ec45987019a604ce24401c91e43 1353 Pfam PF02769 AIR synthase related protein, C-terminal domain 863 1013 3.6E-13 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS12440 d10c0e7970bcb6861a3677c4a5d1092f 87 SUPERFAMILY SSF56601 15 86 1.73E-21 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS12440 d10c0e7970bcb6861a3677c4a5d1092f 87 Gene3D G3DSA:3.40.710.10 7 87 8.4E-23 T 28-03-2018 AFA_RS12440 d10c0e7970bcb6861a3677c4a5d1092f 87 Pfam PF00144 Beta-lactamase 21 86 1.2E-17 T 28-03-2018 IPR001466 Beta-lactamase-related AFA_RS11985 2948054674155de67cac8d22f7218606 369 Gene3D G3DSA:3.40.640.10 15 266 1.0E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS11985 2948054674155de67cac8d22f7218606 369 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 367 6.4E-141 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFA_RS11985 2948054674155de67cac8d22f7218606 369 PIRSF PIRSF000525 1 369 4.0E-137 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFA_RS11985 2948054674155de67cac8d22f7218606 369 Gene3D G3DSA:3.90.1150.10 267 367 9.7E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS11985 2948054674155de67cac8d22f7218606 369 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 368 47.567 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFA_RS11985 2948054674155de67cac8d22f7218606 369 Pfam PF00266 Aminotransferase class-V 3 357 1.2E-44 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS11985 2948054674155de67cac8d22f7218606 369 SUPERFAMILY SSF53383 2 368 1.28E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SMART SM01086 769 858 5.6E-39 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SUPERFAMILY SSF52540 159 548 2.57E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Gene3D G3DSA:1.10.8.60 343 551 1.2E-42 T 28-03-2018 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SUPERFAMILY SSF52540 550 858 8.66E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 9.8E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 9.7E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 9.9E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 6.9E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 6.9E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 6.9E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 6.9E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Gene3D G3DSA:3.40.50.300 556 768 1.1E-51 T 28-03-2018 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Gene3D G3DSA:1.10.1780.10 1 151 1.8E-31 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SUPERFAMILY SSF81923 4 141 4.51E-36 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 847 1.0E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SMART SM00382 198 344 7.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 SMART SM00382 601 755 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Gene3D G3DSA:1.10.8.60 769 863 2.2E-23 T 28-03-2018 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 763 2.3E-57 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS11720 4036a12ce2b03e8c4d734dac92f59af1 863 Gene3D G3DSA:3.40.50.300 157 342 2.9E-25 T 28-03-2018 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 53 66 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 SUPERFAMILY SSF53850 6 249 1.99E-77 T 28-03-2018 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 Gene3D G3DSA:3.40.190.10 152 252 6.3E-20 T 28-03-2018 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 SMART SM00079 31 249 1.9E-8 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 249 3.9E-71 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 Gene3D G3DSA:3.40.190.10 22 151 4.4E-41 T 28-03-2018 AFA_RS03775 1e08de644c35eb8ee75b5f1c632ffe1a 252 SMART SM00062 31 250 5.4E-70 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS10640 bf897362170f4375035141e37676ee00 163 Pfam PF14437 MafB19-like deaminase 2 143 2.2E-26 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFA_RS10640 bf897362170f4375035141e37676ee00 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFA_RS10640 bf897362170f4375035141e37676ee00 163 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 143 42.21 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFA_RS10640 bf897362170f4375035141e37676ee00 163 SUPERFAMILY SSF53927 1 147 2.51E-51 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFA_RS10640 bf897362170f4375035141e37676ee00 163 Gene3D G3DSA:3.40.140.10 1 153 4.8E-48 T 28-03-2018 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 9 394 4.8E-112 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 Gene3D G3DSA:3.90.1150.10 265 398 9.7E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 Gene3D G3DSA:3.40.640.10 5 264 3.3E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 24 393 5.2E-100 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 SUPERFAMILY SSF53383 44 394 1.84E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS00705 50ea6340484689e3dbc842be868748a4 398 PIRSF PIRSF001434 1 396 6.4E-120 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 SUPERFAMILY SSF55961 166 392 3.57E-25 T 28-03-2018 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 Gene3D G3DSA:2.102.10.10 49 155 1.1E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 SUPERFAMILY SSF50022 22 163 2.88E-42 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 189 387 5.5E-22 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 Pfam PF00355 Rieske [2Fe-2S] domain 51 132 4.5E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 66 81 7.5E-18 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 107 127 7.5E-18 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 36 61 7.5E-18 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 149 175 7.5E-18 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS03295 0652223213118a80c9335c5f94df8122 407 Gene3D G3DSA:3.90.380.10 156 400 3.2E-33 T 28-03-2018 AFA_RS17110 0ca3cd92fb8f5550ef9a9e38e2da2099 223 Gene3D G3DSA:3.10.450.50 49 97 0.0022 T 28-03-2018 AFA_RS17110 0ca3cd92fb8f5550ef9a9e38e2da2099 223 Gene3D G3DSA:3.10.450.50 98 185 1.0E-24 T 28-03-2018 AFA_RS17110 0ca3cd92fb8f5550ef9a9e38e2da2099 223 Pfam PF05494 MlaC protein 56 220 1.8E-54 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFA_RS17110 0ca3cd92fb8f5550ef9a9e38e2da2099 223 PIRSF PIRSF004649 20 223 3.0E-50 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFA_RS17110 0ca3cd92fb8f5550ef9a9e38e2da2099 223 Gene3D G3DSA:1.10.10.640 186 223 2.2E-6 T 28-03-2018 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Gene3D G3DSA:1.10.760.10 507 668 1.1E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Gene3D G3DSA:1.10.760.10 817 935 2.8E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SUPERFAMILY SSF46626 837 935 4.43E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Gene3D G3DSA:1.10.760.10 696 816 2.5E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SUPERFAMILY SSF56003 128 496 6.69E-24 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SUPERFAMILY SSF46626 553 676 7.84E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SUPERFAMILY SSF46626 692 809 2.6E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Gene3D G3DSA:3.30.365.10 286 506 4.4E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Pfam PF00034 Cytochrome c 703 806 3.7E-4 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Pfam PF00034 Cytochrome c 555 654 8.2E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 837 918 5.6E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 Gene3D G3DSA:3.90.1170.50 12 129 6.4E-10 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SMART SM01008 8 94 3.4E-5 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS14975 bd3e60810be9580e8f3f03383c0d5c11 946 SUPERFAMILY SSF54665 21 91 1.3E-6 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 SUPERFAMILY SSF46785 151 228 1.81E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 Pfam PF13545 Crp-like helix-turn-helix domain 153 225 1.1E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 SMART SM00419 172 220 1.7E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 SMART SM00100 15 136 2.2E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 SUPERFAMILY SSF51206 9 145 7.46E-27 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 Gene3D G3DSA:2.60.120.10 5 148 6.0E-25 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 7.5E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS15970 f016fdadf1f3bb36fa46fc5d90c19a49 232 Gene3D G3DSA:1.10.10.10 149 229 3.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 SMART SM01016 7 93 1.8E-32 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Pfam PF00750 tRNA synthetases class I (R) 108 405 1.2E-19 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Gene3D G3DSA:3.40.50.620 332 418 3.2E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 561 25.416 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 SUPERFAMILY SSF47323 439 561 2.03E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 1.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 311 332 1.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 1.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 1.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 93 9.4E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 SMART SM00836 444 561 8.7E-50 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 131 140 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 SUPERFAMILY SSF52374 118 454 9.38E-82 T 28-03-2018 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Pfam PF05746 DALR anticodon binding domain 444 561 2.7E-33 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Gene3D G3DSA:3.30.1360.70 1 116 3.6E-30 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Gene3D G3DSA:3.40.50.620 118 331 5.8E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 6 561 5.5E-131 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 Gene3D G3DSA:1.10.730.10 419 561 3.7E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS00720 d3b9869ef4a2afefbde0f875b9aa0b88 561 SUPERFAMILY SSF55190 6 113 6.02E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFA_RS11170 9a1107b468a0f3735b111beb2f276939 295 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 32 281 1.1E-93 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 AFA_RS11170 9a1107b468a0f3735b111beb2f276939 295 Gene3D G3DSA:1.10.3720.10 30 293 3.4E-39 T 28-03-2018 AFA_RS11170 9a1107b468a0f3735b111beb2f276939 295 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 30 288 1.5E-118 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 AFA_RS11170 9a1107b468a0f3735b111beb2f276939 295 SUPERFAMILY SSF161098 31 283 1.57E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11170 9a1107b468a0f3735b111beb2f276939 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 288 2.7E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18170 012c3263e16c976bb472baeec5501be8 190 SUPERFAMILY SSF54626 22 187 1.7E-19 T 28-03-2018 IPR016087 Chalcone isomerase GO:0016872 AFA_RS18170 012c3263e16c976bb472baeec5501be8 190 Gene3D G3DSA:3.50.70.10 19 172 2.0E-26 T 28-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 AFA_RS18170 012c3263e16c976bb472baeec5501be8 190 Pfam PF16036 Chalcone isomerase-like 22 188 9.5E-46 T 28-03-2018 IPR016087 Chalcone isomerase GO:0016872 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Pfam PF00684 DnaJ central domain 150 210 1.2E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Gene3D G3DSA:2.60.260.20 209 257 1.1E-11 T 28-03-2018 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Pfam PF01556 DnaJ C terminal domain 124 336 1.8E-40 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 PRINTS PR00625 DnaJ domain signature 42 62 1.3E-32 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 PRINTS PR00625 DnaJ domain signature 7 25 1.3E-32 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 PRINTS PR00625 DnaJ domain signature 62 81 1.3E-32 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 PRINTS PR00625 DnaJ domain signature 25 40 1.3E-32 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SUPERFAMILY SSF49493 217 259 7.85E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SUPERFAMILY SSF49493 118 141 7.85E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Gene3D G3DSA:1.10.287.110 1 113 5.5E-36 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 352 8.1E-136 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Gene3D G3DSA:2.60.260.20 258 368 9.9E-30 T 28-03-2018 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 41.376 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Gene3D G3DSA:2.10.230.10 147 208 6.6E-18 T 28-03-2018 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SUPERFAMILY SSF49493 262 347 5.49E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SUPERFAMILY SSF57938 137 214 6.28E-22 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SMART SM00271 4 62 1.1E-31 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 SUPERFAMILY SSF46565 1 114 4.97E-37 T 28-03-2018 IPR001623 DnaJ domain AFA_RS13745 8b0436f52684be64e88ca329fb50b6fd 377 Pfam PF00226 DnaJ domain 5 67 2.9E-28 T 28-03-2018 IPR001623 DnaJ domain AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 Gene3D G3DSA:1.10.10.10 1 82 4.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 Gene3D G3DSA:1.20.120.530 83 213 6.9E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 70 4.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 SUPERFAMILY SSF48008 79 206 2.14E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 Pfam PF07729 FCD domain 84 204 1.6E-20 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 SUPERFAMILY SSF46785 10 70 1.29E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 SMART SM00345 17 73 3.9E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00985 3ad607b0ae94cb1e8e14333cfd2dc0a8 223 SMART SM00895 84 208 6.8E-13 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 SMART SM00342 189 271 6.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 SUPERFAMILY SSF46689 227 273 7.17E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 SUPERFAMILY SSF46689 175 223 1.89E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 Pfam PF02311 AraC-like ligand binding domain 20 150 1.8E-21 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 267 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 Gene3D G3DSA:2.60.120.10 11 108 1.1E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 SUPERFAMILY SSF51215 16 156 7.85E-17 T 28-03-2018 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 Pfam PF12833 Helix-turn-helix domain 195 269 1.1E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 Gene3D G3DSA:1.10.10.60 174 227 1.4E-13 T 28-03-2018 AFA_RS16125 78630ce42c71c86428f63be914e696e0 283 Gene3D G3DSA:1.10.10.60 228 283 7.8E-9 T 28-03-2018 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 SUPERFAMILY SSF81338 4 229 1.02E-64 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 45 69 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 138 156 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 207 227 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 168 190 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 PRINTS PR00783 Major intrinsic protein family signature 82 101 1.8E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 Hamap MF_01146 Aquaporin Z [aqpZ]. 4 231 33.368 T 28-03-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 Gene3D G3DSA:1.20.1080.10 1 232 1.4E-68 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 224 4.8E-58 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 ProSitePatterns PS00221 MIP family signature. 63 71 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS06185 03aea63cc84b2195cae42d5cee446f10 232 Pfam PF00230 Major intrinsic protein 2 224 3.8E-50 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 65 4.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 Gene3D G3DSA:1.20.120.530 88 245 5.6E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 Gene3D G3DSA:1.10.10.10 1 68 8.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 Pfam PF07729 FCD domain 94 223 2.3E-24 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 SUPERFAMILY SSF46785 2 70 3.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 SMART SM00345 7 66 4.0E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 SUPERFAMILY SSF48008 92 232 4.45E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS02220 3cf882aa9de64346cd738b2ea287ac34 259 SMART SM00895 94 225 1.9E-20 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 SUPERFAMILY SSF52833 1 88 1.29E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 190 5.4E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 Gene3D G3DSA:1.20.1050.10 93 204 1.2E-24 T 28-03-2018 AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 Gene3D G3DSA:3.40.30.10 1 92 8.8E-31 T 28-03-2018 AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 8.4E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS08095 b7c72d466b4c83a63d80e4b81c726ba3 204 SUPERFAMILY SSF47616 71 197 2.92E-26 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Pfam PF00005 ABC transporter 289 433 5.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Pfam PF00005 ABC transporter 25 172 1.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Pfam PF12698 ABC-2 family transporter protein 569 902 1.3E-39 T 28-03-2018 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 SUPERFAMILY SSF52540 268 495 2.1E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Gene3D G3DSA:3.40.50.300 271 548 1.5E-64 T 28-03-2018 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Gene3D G3DSA:3.40.50.300 7 263 1.7E-57 T 28-03-2018 AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 SUPERFAMILY SSF52540 12 236 5.7E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 SMART SM00382 298 483 2.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 SMART SM00382 34 261 0.023 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14025 f1ea0d167062dbe32c3916b665415cb7 911 Gene3D G3DSA:3.40.1710.10 577 730 1.8E-25 T 28-03-2018 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 SUPERFAMILY SSF81891 181 411 1.26E-41 T 28-03-2018 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Gene3D G3DSA:3.30.460.10 25 178 1.8E-50 T 28-03-2018 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 211 269 1.2E-14 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 SUPERFAMILY SSF81301 32 179 1.31E-40 T 28-03-2018 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Pfam PF12626 Polymerase A arginine-rich C-terminus 322 445 7.9E-33 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Gene3D G3DSA:1.10.3090.10 179 437 1.3E-37 T 28-03-2018 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 22 447 34.829 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 Pfam PF01743 Poly A polymerase head domain 58 182 3.8E-36 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFA_RS03895 03ebd0b21bf20f5909832057be1b48f8 459 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 28 449 2.4E-148 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 Pfam PF03466 LysR substrate binding domain 88 290 4.7E-47 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 Gene3D G3DSA:1.10.10.10 1 86 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 9.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 9.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 SUPERFAMILY SSF53850 89 291 4.25E-46 T 28-03-2018 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 SUPERFAMILY SSF46785 4 110 1.19E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 Gene3D G3DSA:3.40.190.10 89 176 2.6E-24 T 28-03-2018 AFA_RS05645 6c15ede50f844e2fa6b71ac9e3024ba6 301 Gene3D G3DSA:3.40.190.10 177 261 4.2E-18 T 28-03-2018 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 5.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 SUPERFAMILY SSF46785 5 81 8.18E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 Gene3D G3DSA:3.40.190.10 178 258 9.3E-16 T 28-03-2018 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 SUPERFAMILY SSF53850 94 290 6.33E-31 T 28-03-2018 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 Gene3D G3DSA:3.40.190.10 85 177 2.9E-14 T 28-03-2018 AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 Gene3D G3DSA:1.10.10.10 4 84 8.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03470 3b7f1257238075a864a2fe496c4c0863 293 Pfam PF03466 LysR substrate binding domain 91 288 1.8E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 336 4.7E-81 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 Gene3D G3DSA:1.10.287.470 101 148 7.4E-11 T 28-03-2018 AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 256 5.1E-30 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 Gene3D G3DSA:2.40.50.100 149 322 5.8E-8 T 28-03-2018 AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 Gene3D G3DSA:3.90.1170.30 24 100 0.0098 T 28-03-2018 AFA_RS15190 d9d84c6f31ba9c49d8c7cf4c113ad8ba 348 SUPERFAMILY SSF111369 47 262 3.53E-49 T 28-03-2018 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 49.757 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 SUPERFAMILY SSF56762 16 417 6.54E-136 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 3.3E-122 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 3.0E-186 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 Gene3D G3DSA:1.10.645.10 2 234 6.7E-62 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13405 2c7122184b7bcb73b841ae39dc3abc9a 417 Gene3D G3DSA:1.10.645.10 235 409 5.2E-44 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 SUPERFAMILY SSF142754 40 350 9.68E-101 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 40 350 1.7E-100 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 Pfam PF02445 Quinolinate synthetase A protein 45 348 3.6E-98 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 Gene3D G3DSA:3.40.50.10800 37 126 1.2E-16 T 28-03-2018 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 Gene3D G3DSA:3.40.50.10800 220 332 4.6E-31 T 28-03-2018 AFA_RS08400 a5361b959baccf35418f487b2dffb193 377 Gene3D G3DSA:3.40.50.10800 128 219 1.7E-20 T 28-03-2018 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 787 1.6E-56 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Gene3D G3DSA:3.30.470.20 191 355 6.5E-45 T 28-03-2018 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 347 8.8E-117 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Gene3D G3DSA:3.30.1490.20 1 190 2.5E-57 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 692 710 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Gene3D G3DSA:3.50.30.10 356 476 3.5E-37 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 PIRSF PIRSF000854 1 788 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 SUPERFAMILY SSF51621 463 787 1.49E-90 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 SUPERFAMILY SSF52009 345 465 8.89E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 788 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 453 8.5E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 SUPERFAMILY SSF56059 1 382 2.35E-106 T 28-03-2018 AFA_RS10120 2f70a4cfee4cae02b6e284330112d94f 788 Gene3D G3DSA:3.20.20.60 477 788 1.2E-99 T 28-03-2018 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 SUPERFAMILY SSF51905 19 123 1.53E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 SUPERFAMILY SSF51905 261 336 1.53E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Gene3D G3DSA:3.50.50.60 147 266 4.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Gene3D G3DSA:3.90.760.10 341 408 3.0E-23 T 28-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 340 407 1.8E-24 T 28-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 SUPERFAMILY SSF55424 340 408 3.57E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Gene3D G3DSA:3.50.50.60 105 146 0.079 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 131 2.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 Gene3D G3DSA:3.50.50.60 10 104 3.0E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06225 af8f6a956c0965308e0ec32c72b71221 411 SUPERFAMILY SSF51905 130 266 5.76E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS12795 7f68a063f659af5495e18836e004ba64 473 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 411 2.1E-61 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS12795 7f68a063f659af5495e18836e004ba64 473 Pfam PF01554 MatE 31 182 2.5E-20 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS12795 7f68a063f659af5495e18836e004ba64 473 Pfam PF01554 MatE 247 407 8.4E-20 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 Gene3D G3DSA:3.40.190.10 94 180 2.9E-16 T 28-03-2018 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 Gene3D G3DSA:3.40.190.10 181 271 1.5E-15 T 28-03-2018 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 SUPERFAMILY SSF53850 95 299 3.67E-35 T 28-03-2018 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 6.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 SUPERFAMILY SSF46785 6 116 7.26E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 Pfam PF03466 LysR substrate binding domain 93 298 8.9E-34 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS04440 fab90a66572f2bf873cd58840a8b1e2d 308 Gene3D G3DSA:1.10.10.10 1 88 9.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 Gene3D G3DSA:3.40.50.2000 1 172 1.4E-38 T 28-03-2018 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 5 348 1.0E-98 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 143 1.5E-36 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 Gene3D G3DSA:3.40.50.2000 173 337 5.7E-23 T 28-03-2018 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 353 33.701 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 341 8.6E-37 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 AFA_RS03665 d9c8aa4e80bd52cdc0095a5febeda571 357 SUPERFAMILY SSF53756 5 354 1.23E-117 T 28-03-2018 AFA_RS13715 fbcfa1b26ac76ef07a889c594ac1f58f 589 Pfam PF15984 Bacterial collagen, middle region 82 185 1.0E-14 T 28-03-2018 IPR031929 Bacterial collagen-like protein, middle domain AFA_RS13715 fbcfa1b26ac76ef07a889c594ac1f58f 589 Pfam PF15984 Bacterial collagen, middle region 190 345 6.2E-14 T 28-03-2018 IPR031929 Bacterial collagen-like protein, middle domain AFA_RS13715 fbcfa1b26ac76ef07a889c594ac1f58f 589 Gene3D G3DSA:1.20.120.20 242 447 0.0069 T 28-03-2018 AFA_RS13715 fbcfa1b26ac76ef07a889c594ac1f58f 589 Gene3D G3DSA:1.20.120.20 70 209 0.024 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82866 296 495 1.31E-47 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:3.30.70.1430 46 147 7.0E-25 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:1.20.1640.10 290 507 4.8E-42 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82714 705 789 9.42E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:3.30.2090.10 186 273 9.7E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82693 47 140 1.74E-23 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82866 790 1011 2.09E-44 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 16 40 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 44 62 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 609 623 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 362 383 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 8.7E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82714 189 270 1.57E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Pfam PF00873 AcrB/AcrD/AcrF family 10 1009 1.4E-271 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82693 559 656 5.07E-16 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:3.30.70.1430 561 653 6.8E-7 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:1.20.1640.10 790 1012 5.2E-43 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 Gene3D G3DSA:3.30.2090.10 704 789 3.1E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82693 273 327 2.44E-18 T 28-03-2018 AFA_RS14115 446398a30d74ece43710e23bc33f58b8 1038 SUPERFAMILY SSF82693 143 187 2.44E-18 T 28-03-2018 AFA_RS16330 e48b9100b9a99f5552f2d614fb05cecf 201 Pfam PF08282 haloacid dehalogenase-like hydrolase 106 169 1.8E-4 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16330 e48b9100b9a99f5552f2d614fb05cecf 201 SUPERFAMILY SSF56784 28 186 5.47E-36 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16330 e48b9100b9a99f5552f2d614fb05cecf 201 Gene3D G3DSA:3.40.50.1000 24 196 1.0E-23 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16330 e48b9100b9a99f5552f2d614fb05cecf 201 PIRSF PIRSF006118 18 191 9.1E-61 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS16330 e48b9100b9a99f5552f2d614fb05cecf 201 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 31 182 3.6E-42 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 SUPERFAMILY SSF51556 233 525 1.49E-21 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 SUPERFAMILY SSF51556 86 133 1.49E-21 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 Gene3D G3DSA:2.30.40.10 511 573 1.4E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 SUPERFAMILY SSF51338 24 87 2.88E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 SUPERFAMILY SSF51338 524 567 2.88E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 Pfam PF07969 Amidohydrolase family 76 565 6.9E-104 T 28-03-2018 IPR013108 Amidohydrolase 3 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 Gene3D G3DSA:2.30.40.10 28 98 7.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS02255 2e137091389e7db7080cfafa3aa87ca9 620 Gene3D G3DSA:3.20.20.140 99 510 4.7E-37 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 SMART SM00968 518 625 4.7E-5 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:1.10.287.620 740 888 0.0082 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:1.10.287.620 231 384 1.5E-7 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:1.20.5.170 656 739 0.14 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:1.20.5.170 385 505 0.0011 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 SUPERFAMILY SSF52540 1051 1167 1.76E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 SUPERFAMILY SSF52540 2 213 1.76E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1165 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 PIRSF PIRSF005719 1 1173 2.1E-244 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1158 1.1E-63 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1167 22.082 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:3.40.50.300 906 1170 1.1E-27 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 SUPERFAMILY SSF57997 236 477 9.81E-5 T 28-03-2018 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Pfam PF06470 SMC proteins Flexible Hinge Domain 522 624 3.3E-6 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 SUPERFAMILY SSF75553 519 673 6.93E-8 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFA_RS13290 f48da871666c75158fc2b907a81694a3 1174 Gene3D G3DSA:3.40.50.300 2 230 1.0E-36 T 28-03-2018 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 SUPERFAMILY SSF50447 207 303 1.96E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 2.7E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 SUPERFAMILY SSF50465 304 396 2.3E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Gene3D G3DSA:3.40.50.300 2 74 5.2E-11 T 28-03-2018 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 7.0E-228 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.1E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 SUPERFAMILY SSF52540 5 221 6.49E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Gene3D G3DSA:2.40.30.10 302 395 1.4E-32 T 28-03-2018 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.96 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 7.9E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Gene3D G3DSA:2.40.30.10 208 301 2.2E-31 T 28-03-2018 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 8.3E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18385 69d71e0e0953599c74a7a2c85c247796 396 Gene3D G3DSA:3.40.50.300 75 205 1.8E-29 T 28-03-2018 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 Gene3D G3DSA:3.40.366.10 187 311 2.4E-29 T 28-03-2018 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 SUPERFAMILY SSF52151 2 126 2.62E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 SUPERFAMILY SSF52151 197 297 2.62E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 SUPERFAMILY SSF55048 127 196 8.37E-17 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 299 5.0E-34 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 290 3.8E-105 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 PIRSF PIRSF000446 1 310 2.1E-108 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 Pfam PF00698 Acyl transferase domain 5 282 3.9E-34 T 28-03-2018 IPR014043 Acyl transferase AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 Gene3D G3DSA:3.30.70.250 141 186 1.2E-21 T 28-03-2018 AFA_RS13115 4ad802b317e35ba37571f267bd9c8543 312 Gene3D G3DSA:3.40.366.10 2 140 1.5E-36 T 28-03-2018 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Pfam PF08521 Two-component sensor kinase N-terminal 41 172 4.7E-8 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 5.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 5.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 SUPERFAMILY SSF55874 303 461 4.32E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Gene3D G3DSA:1.20.5.1040 149 197 2.8E-6 T 28-03-2018 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Gene3D G3DSA:1.20.5.1040 25 76 4.2E-6 T 28-03-2018 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 461 9.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 SMART SM00387 353 463 2.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Gene3D G3DSA:3.30.565.10 310 463 7.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 SUPERFAMILY SSF47384 233 312 2.35E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 311 2.9E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 SMART SM00388 250 313 8.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15425 d9bcbeff35c3f237066b6c4c2fab0f22 463 Gene3D G3DSA:1.10.287.130 240 309 2.7E-12 T 28-03-2018 AFA_RS10100 95eee8af078b0c760b0cb35e50beac53 144 Gene3D G3DSA:3.30.530.20 1 144 1.7E-35 T 28-03-2018 IPR023393 START-like domain AFA_RS10100 95eee8af078b0c760b0cb35e50beac53 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 5.1E-32 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 AFA_RS10100 95eee8af078b0c760b0cb35e50beac53 144 SUPERFAMILY SSF55961 1 143 4.77E-38 T 28-03-2018 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 Gene3D G3DSA:3.30.43.10 4 104 1.9E-21 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 Gene3D G3DSA:1.10.45.10 427 466 1.8E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 465 2.6E-65 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 Pfam PF01565 FAD binding domain 52 188 5.6E-37 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 SUPERFAMILY SSF55103 230 469 3.27E-72 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 Gene3D G3DSA:3.30.465.10 105 248 1.8E-45 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS12565 4069f8869e07c2ab3342250494442a83 473 SUPERFAMILY SSF56176 13 226 9.35E-69 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 Gene3D G3DSA:3.30.2350.10 58 232 9.9E-32 T 28-03-2018 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 Pfam PF00849 RNA pseudouridylate synthase 61 191 2.2E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 Pfam PF01479 S4 domain 1 47 1.3E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 SUPERFAMILY SSF55120 60 226 4.32E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 222 4.8E-41 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 Gene3D G3DSA:3.10.290.10 1 57 5.3E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 SUPERFAMILY SSF55174 1 55 4.12E-13 T 28-03-2018 AFA_RS00020 ced42813f3f5af06c385814813d77c69 233 SMART SM00363 1 58 1.8E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 5.0E-16 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 PRINTS PR00045 Sigma-54 factor signature 430 448 4.2E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 PRINTS PR00045 Sigma-54 factor signature 169 186 4.2E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 PRINTS PR00045 Sigma-54 factor signature 355 367 4.2E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 PRINTS PR00045 Sigma-54 factor signature 371 382 4.2E-26 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 Gene3D G3DSA:1.10.10.10 301 393 6.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00760 3235fb0c6482080c78093e808a940355 461 Pfam PF04552 Sigma-54, DNA binding domain 301 454 4.9E-55 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding AFA_RS00760 3235fb0c6482080c78093e808a940355 461 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 454 2.0E-113 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 PIRSF PIRSF000774 1 457 2.3E-124 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 Pfam PF04963 Sigma-54 factor, core binding domain 99 284 3.4E-41 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 435 442 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS00760 3235fb0c6482080c78093e808a940355 461 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 343 362 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS17445 57ee52863a4244463878061068a44b83 639 SUPERFAMILY SSF55781 63 203 9.81E-7 T 28-03-2018 IPR029016 GAF domain-like AFA_RS17445 57ee52863a4244463878061068a44b83 639 Pfam PF01590 GAF domain 80 197 4.6E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 AFA_RS17445 57ee52863a4244463878061068a44b83 639 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 425 440 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFA_RS17445 57ee52863a4244463878061068a44b83 639 SUPERFAMILY SSF52540 339 580 1.14E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17445 57ee52863a4244463878061068a44b83 639 Pfam PF00158 Sigma-54 interaction domain 340 504 1.7E-58 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS17445 57ee52863a4244463878061068a44b83 639 SMART SM00382 359 502 6.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS17445 57ee52863a4244463878061068a44b83 639 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 548 557 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site AFA_RS17445 57ee52863a4244463878061068a44b83 639 Gene3D G3DSA:1.10.10.60 579 639 6.3E-14 T 28-03-2018 AFA_RS17445 57ee52863a4244463878061068a44b83 639 Pfam PF02954 Bacterial regulatory protein, Fis family 604 633 2.0E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS17445 57ee52863a4244463878061068a44b83 639 Gene3D G3DSA:3.30.450.40 24 213 1.9E-11 T 28-03-2018 IPR029016 GAF domain-like AFA_RS17445 57ee52863a4244463878061068a44b83 639 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 618 638 1.3E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS17445 57ee52863a4244463878061068a44b83 639 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 601 618 1.3E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS17445 57ee52863a4244463878061068a44b83 639 SUPERFAMILY SSF46689 604 637 1.49E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS17445 57ee52863a4244463878061068a44b83 639 Gene3D G3DSA:3.40.50.300 335 510 1.5E-24 T 28-03-2018 AFA_RS17445 57ee52863a4244463878061068a44b83 639 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 363 376 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS17445 57ee52863a4244463878061068a44b83 639 Gene3D G3DSA:1.10.8.60 511 578 7.8E-17 T 28-03-2018 AFA_RS09500 3c7ad31952c805ed6f779e6d801fae34 146 Gene3D G3DSA:3.40.50.450 1 146 2.0E-23 T 28-03-2018 AFA_RS09500 3c7ad31952c805ed6f779e6d801fae34 146 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 143 6.8E-67 T 28-03-2018 IPR019884 YtoQ family protein AFA_RS09500 3c7ad31952c805ed6f779e6d801fae34 146 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 144 1.9E-67 T 28-03-2018 IPR019884 YtoQ family protein AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 342 354 5.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 273 283 5.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 392 408 5.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 244 258 5.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 446 463 5.7E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 Pfam PF01189 16S rRNA methyltransferase RsmB/F 263 461 5.7E-45 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 Gene3D G3DSA:3.30.70.1170 183 253 6.3E-13 T 28-03-2018 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 Gene3D G3DSA:3.40.50.150 254 468 5.7E-55 T 28-03-2018 AFA_RS07525 98c162d5f28df18e8258f9ddcef1bb5f 468 SUPERFAMILY SSF53335 156 463 1.8E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS05740 3be0a699c7cf0e54a4775409195c748f 312 SUPERFAMILY SSF103088 151 261 1.96E-19 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS05740 3be0a699c7cf0e54a4775409195c748f 312 Gene3D G3DSA:3.30.1330.60 104 292 7.6E-31 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS05740 3be0a699c7cf0e54a4775409195c748f 312 Pfam PF00691 OmpA family 157 253 5.8E-12 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS05740 3be0a699c7cf0e54a4775409195c748f 312 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 12 64 1.5E-19 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 Gene3D G3DSA:1.10.580.10 26 366 3.0E-80 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PRINTS PR00143 Citrate synthase signature 262 282 3.4E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PRINTS PR00143 Citrate synthase signature 339 353 3.4E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PRINTS PR00143 Citrate synthase signature 187 202 3.4E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PRINTS PR00143 Citrate synthase signature 209 237 3.4E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PRINTS PR00143 Citrate synthase signature 319 335 3.4E-34 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 19 386 3.3E-155 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 Pfam PF00285 Citrate synthase, C-terminal domain 20 369 1.2E-111 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 ProSitePatterns PS00480 Citrate synthase signature. 269 281 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 PIRSF PIRSF001369 13 387 3.6E-109 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type AFA_RS04810 dbfcba84ae85b142c92b0e486031f194 387 SUPERFAMILY SSF48256 20 380 1.1E-122 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 SUPERFAMILY SSF47757 8 83 5.49E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 SUPERFAMILY SSF53335 84 273 3.81E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 Gene3D G3DSA:3.40.50.150 83 276 5.2E-47 T 28-03-2018 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PIRSF PIRSF000410 6 276 1.3E-84 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 Gene3D G3DSA:1.10.155.10 10 82 1.1E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 Pfam PF03705 CheR methyltransferase, all-alpha domain 20 68 1.6E-5 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 Pfam PF01739 CheR methyltransferase, SAM binding domain 84 273 5.3E-57 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 SMART SM00138 16 276 1.5E-87 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 77 89 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 38 51 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 144 160 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 235 258 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 216 230 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS05760 cbd779b93a9959867b2d1bf4b56988a9 276 PRINTS PR00996 Glutamate methyltransferase family signature 110 130 2.5E-37 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 10 294 2.2E-127 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 257 6.8E-52 T 28-03-2018 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 SUPERFAMILY SSF51621 5 293 7.63E-101 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 Gene3D G3DSA:3.20.20.60 5 299 6.0E-91 T 28-03-2018 AFA_RS04815 cf884b60cbd90010093e176ec10a2e6e 299 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 7 295 48.831 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 SMART SM01329 30 414 9.6E-173 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 SUPERFAMILY SSF53659 4 418 7.68E-145 T 28-03-2018 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 413 1.4E-114 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 Gene3D G3DSA:3.40.718.10 10 418 1.5E-129 T 28-03-2018 AFA_RS13600 cf9aef76f4ce5e7e858bbc134571476d 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 1.7E-222 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFA_RS11050 695d4cb2f4f377b76cc7440e4ecc4473 522 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AFA_RS11050 695d4cb2f4f377b76cc7440e4ecc4473 522 Pfam PF00474 Sodium:solute symporter family 33 442 2.8E-96 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS11050 695d4cb2f4f377b76cc7440e4ecc4473 522 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 442 8.0E-61 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS18545 5531af764b113c91ef3516a06dba2e0b 242 Gene3D G3DSA:3.40.50.300 6 240 6.7E-59 T 28-03-2018 AFA_RS18545 5531af764b113c91ef3516a06dba2e0b 242 SMART SM00382 34 227 8.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS18545 5531af764b113c91ef3516a06dba2e0b 242 Pfam PF00005 ABC transporter 25 170 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18545 5531af764b113c91ef3516a06dba2e0b 242 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS18545 5531af764b113c91ef3516a06dba2e0b 242 SUPERFAMILY SSF52540 7 240 4.33E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 Gene3D G3DSA:3.40.190.10 183 272 1.1E-6 T 28-03-2018 AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 Pfam PF03466 LysR substrate binding domain 95 301 2.8E-28 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 Gene3D G3DSA:3.40.190.10 96 182 2.6E-18 T 28-03-2018 AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 SUPERFAMILY SSF46785 9 92 4.94E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 Gene3D G3DSA:1.10.10.10 3 90 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17405 2e348f984ea6f12d4a11f7af8a8e3344 314 SUPERFAMILY SSF53850 97 306 3.45E-31 T 28-03-2018 AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 197 6.9E-25 T 28-03-2018 AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 Gene3D G3DSA:3.40.50.1000 86 219 2.5E-10 T 28-03-2018 IPR023214 HAD-like domain AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 SUPERFAMILY SSF56784 7 218 2.58E-32 T 28-03-2018 IPR023214 HAD-like domain AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 7 209 2.2E-41 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 196 3.8E-39 T 28-03-2018 AFA_RS03900 e2300da1693b7c9977ea523bd9b252ed 233 Gene3D G3DSA:1.20.1440.100 20 85 1.6E-20 T 28-03-2018 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 PIRSF PIRSF000005 39 265 2.8E-63 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 Pfam PF00034 Cytochrome c 97 161 3.1E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 SUPERFAMILY SSF46626 97 164 2.91E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 SUPERFAMILY SSF46626 174 263 7.8E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 Gene3D G3DSA:1.10.760.10 66 162 1.2E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06390 0e34329fffeb41db1d707c0e772a5691 271 Gene3D G3DSA:1.10.760.10 164 263 6.6E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 SUPERFAMILY SSF52172 1 173 1.42E-39 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 SMART SM00448 1 112 2.0E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 SMART SM00862 145 218 3.5E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 Gene3D G3DSA:1.10.10.10 118 225 3.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11145 2eca8e63edc309b7f5664b8fdbfc2250 226 Gene3D G3DSA:3.40.50.2300 1 117 1.5E-35 T 28-03-2018 AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 Gene3D G3DSA:3.40.640.10 16 256 4.3E-21 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 186 205 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 Gene3D G3DSA:3.90.1150.10 257 358 2.9E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 PIRSF PIRSF000525 1 360 5.7E-130 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 Pfam PF00266 Aminotransferase class-V 5 348 9.4E-39 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 43.757 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFA_RS14065 e5ce3b61a1f9795f6c1999e0ffd9ce64 360 SUPERFAMILY SSF53383 1 357 2.18E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS13895 f94fc115521847065feeb3e299c55675 101 Gene3D G3DSA:1.10.260.40 4 100 4.0E-7 T 28-03-2018 AFA_RS13895 f94fc115521847065feeb3e299c55675 101 Pfam PF01381 Helix-turn-helix 49 93 2.2E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS13895 f94fc115521847065feeb3e299c55675 101 SUPERFAMILY SSF47413 30 93 3.85E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS13895 f94fc115521847065feeb3e299c55675 101 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 5 93 5.2E-39 T 28-03-2018 IPR014057 Addiction module antidote protein, HI1420 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Gene3D G3DSA:3.40.120.10 160 273 3.3E-33 T 28-03-2018 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 433 2.6E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 SUPERFAMILY SSF53738 262 368 2.12E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 447 45.726 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Gene3D G3DSA:3.40.120.10 3 158 8.4E-51 T 28-03-2018 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 369 2.8E-32 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Gene3D G3DSA:3.30.310.50 377 443 2.2E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 1.5E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 1.5E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 1.5E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Gene3D G3DSA:3.40.120.10 274 376 3.0E-32 T 28-03-2018 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 SUPERFAMILY SSF55957 360 440 9.03E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 258 1.1E-19 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 441 3.0E-179 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 139 5.3E-45 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 SUPERFAMILY SSF53738 2 185 3.49E-50 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS04180 417fecac38432d3ad5a66afb81a44fa8 447 SUPERFAMILY SSF53738 160 260 2.94E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Pfam PF00364 Biotin-requiring enzyme 603 668 6.5E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.4E-76 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SUPERFAMILY SSF52440 2 113 6.47E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Gene3D G3DSA:3.30.470.20 205 450 6.3E-106 T 28-03-2018 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Gene3D G3DSA:3.30.1490.20 119 204 1.9E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Gene3D G3DSA:3.40.50.20 1 118 2.0E-52 T 28-03-2018 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 625 642 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 2.4E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Gene3D G3DSA:2.40.50.100 600 670 1.6E-19 T 28-03-2018 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SUPERFAMILY SSF51230 596 669 1.7E-21 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SUPERFAMILY SSF56059 83 348 2.47E-69 T 28-03-2018 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SMART SM01209 114 293 0.0047 T 28-03-2018 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SMART SM00878 336 447 1.2E-54 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 SUPERFAMILY SSF51246 331 453 5.02E-39 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFA_RS00670 a5f4b86a5a7a87c0418c70658aebc440 670 Pfam PF02785 Biotin carboxylase C-terminal domain 336 446 4.5E-36 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS13105 78cd8feae14256db9109409517e86613 79 SUPERFAMILY SSF47336 2 76 5.5E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS13105 78cd8feae14256db9109409517e86613 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site AFA_RS13105 78cd8feae14256db9109409517e86613 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.1E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS13105 78cd8feae14256db9109409517e86613 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.719 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFA_RS13105 78cd8feae14256db9109409517e86613 79 Gene3D G3DSA:1.10.1200.10 1 79 5.4E-29 T 28-03-2018 AFA_RS13105 78cd8feae14256db9109409517e86613 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 5.0E-4 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFA_RS13105 78cd8feae14256db9109409517e86613 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 2.0E-35 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFA_RS05235 d764b8142b7dd3a7b6bb21f92e0201df 155 Pfam PF00578 AhpC/TSA family 6 132 9.3E-36 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS05235 d764b8142b7dd3a7b6bb21f92e0201df 155 PIRSF PIRSF000239 1 152 5.6E-31 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS05235 d764b8142b7dd3a7b6bb21f92e0201df 155 SUPERFAMILY SSF52833 4 153 2.76E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS05235 d764b8142b7dd3a7b6bb21f92e0201df 155 Gene3D G3DSA:3.40.30.10 1 154 2.2E-36 T 28-03-2018 AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00722 47 197 1.1E-9 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00722 203 363 2.7E-13 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 177 198 790.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 199 220 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 243 265 4300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 125 146 3.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 147 176 230.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 288 309 540.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 266 287 430.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SMART SM00710 95 123 1300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 Gene3D G3DSA:2.160.20.10 33 253 9.3E-33 T 28-03-2018 IPR012334 Pectin lyase fold AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 SUPERFAMILY SSF51126 34 405 1.57E-72 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 Pfam PF05048 Periplasmic copper-binding protein (NosD) 155 379 5.1E-56 T 28-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 Gene3D G3DSA:2.160.20.10 254 409 2.9E-14 T 28-03-2018 IPR012334 Pectin lyase fold AFA_RS16915 b8a42b1ea19f625b26f80594755d38ee 434 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 40 416 1.6E-141 T 28-03-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 15 667 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Pfam PF12344 Ultra-violet resistance protein B 561 603 3.1E-23 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Hamap MF_00204 UvrABC system protein B [uvrB]. 13 669 43.26 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SMART SM00490 469 555 3.2E-20 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SUPERFAMILY SSF52540 15 424 1.93E-133 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SUPERFAMILY SSF46600 621 668 1.14E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Gene3D G3DSA:3.40.50.300 21 424 9.0E-32 T 28-03-2018 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Gene3D G3DSA:4.10.860.10 612 673 7.7E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SUPERFAMILY SSF52540 468 593 2.26E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SUPERFAMILY SSF52540 47 92 2.26E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 SMART SM00487 19 435 3.3E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Gene3D G3DSA:3.40.50.300 425 598 3.1E-33 T 28-03-2018 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Pfam PF02151 UvrB/uvrC motif 635 668 2.2E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Pfam PF04851 Type III restriction enzyme, res subunit 27 132 1.1E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFA_RS07700 916dbf9ff4d8b4fb5da792878d2d1d53 673 Pfam PF00271 Helicase conserved C-terminal domain 451 553 9.8E-18 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS13285 49ee837a30c383ac3e4f11ea2c9fe32f 340 Gene3D G3DSA:3.30.1400.10 197 319 1.3E-19 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 AFA_RS13285 49ee837a30c383ac3e4f11ea2c9fe32f 340 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 251 314 5.3E-10 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 AFA_RS13285 49ee837a30c383ac3e4f11ea2c9fe32f 340 SUPERFAMILY SSF64383 200 323 6.67E-14 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 AFA_RS13285 49ee837a30c383ac3e4f11ea2c9fe32f 340 SMART SM00771 196 319 3.2E-15 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 AFA_RS13285 49ee837a30c383ac3e4f11ea2c9fe32f 340 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 251 319 0.002 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 AFA_RS09055 c67468dab09aa74f1ee1d96d182a19ec 245 PIRSF PIRSF037290 3 242 4.3E-48 T 28-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 AFA_RS09055 c67468dab09aa74f1ee1d96d182a19ec 245 SUPERFAMILY SSF52540 48 172 1.06E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09055 c67468dab09aa74f1ee1d96d182a19ec 245 Gene3D G3DSA:3.40.50.300 47 173 6.7E-20 T 28-03-2018 AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 SUPERFAMILY SSF55821 6 219 9.77E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 PIRSF PIRSF004930 1 341 6.7E-99 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 Pfam PF01300 Telomere recombination 19 197 2.1E-50 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 Pfam PF03481 Putative GTP-binding controlling metal-binding 210 338 8.7E-20 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 219 4.1E-50 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 AFA_RS03445 149b06d510454ae388ee40cc20f66397 341 Gene3D G3DSA:3.90.870.10 1 223 5.8E-72 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS02400 e40ac947d9afc00a4eff139526dbe510 226 Gene3D G3DSA:2.60.120.620 2 187 2.6E-35 T 28-03-2018 AFA_RS02400 e40ac947d9afc00a4eff139526dbe510 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 1.2E-14 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AFA_RS02400 e40ac947d9afc00a4eff139526dbe510 226 SUPERFAMILY SSF51197 4 177 1.79E-5 T 28-03-2018 AFA_RS02400 e40ac947d9afc00a4eff139526dbe510 226 SMART SM00702 1 177 1.1E-22 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AFA_RS02400 e40ac947d9afc00a4eff139526dbe510 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 44.828 T 28-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 AFA_RS14580 ed71129b8102c86117202440f5fe6de4 345 Gene3D G3DSA:3.40.190.10 142 293 1.3E-25 T 28-03-2018 AFA_RS14580 ed71129b8102c86117202440f5fe6de4 345 Pfam PF13343 Bacterial extracellular solute-binding protein 104 303 1.2E-18 T 28-03-2018 AFA_RS14580 ed71129b8102c86117202440f5fe6de4 345 SUPERFAMILY SSF53850 49 313 1.63E-41 T 28-03-2018 AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 SMART SM00387 349 453 9.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 1.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.5E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 Gene3D G3DSA:3.30.565.10 228 452 1.9E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 448 8.8E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS04240 3ac6c8f4416b294d42a3d15b0e48d459 453 SUPERFAMILY SSF55874 314 451 1.26E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS00675 ccc550ae1002876e1eb6393146b371f6 535 SUPERFAMILY SSF52096 28 268 7.17E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS00675 ccc550ae1002876e1eb6393146b371f6 535 Pfam PF01039 Carboxyl transferase domain 50 525 8.9E-149 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 AFA_RS00675 ccc550ae1002876e1eb6393146b371f6 535 Gene3D G3DSA:3.90.226.10 274 531 5.2E-70 T 28-03-2018 AFA_RS00675 ccc550ae1002876e1eb6393146b371f6 535 SUPERFAMILY SSF52096 275 535 4.52E-87 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS00675 ccc550ae1002876e1eb6393146b371f6 535 Gene3D G3DSA:3.90.226.10 9 273 5.8E-69 T 28-03-2018 AFA_RS02325 c84923b3c801a87287a9015c5132301b 324 Gene3D G3DSA:3.40.190.10 138 234 4.3E-12 T 28-03-2018 AFA_RS02325 c84923b3c801a87287a9015c5132301b 324 Gene3D G3DSA:3.40.190.10 36 137 0.05 T 28-03-2018 AFA_RS02325 c84923b3c801a87287a9015c5132301b 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 3.0E-64 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02325 c84923b3c801a87287a9015c5132301b 324 PIRSF PIRSF017082 1 323 1.1E-68 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02325 c84923b3c801a87287a9015c5132301b 324 SUPERFAMILY SSF53850 111 287 1.09E-12 T 28-03-2018 AFA_RS02890 364816361f80a334c86b528d968067df 222 PIRSF PIRSF002764 1 222 6.4E-74 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria AFA_RS02890 364816361f80a334c86b528d968067df 222 Pfam PF03379 CcmB protein 6 218 1.5E-68 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 9.1E-55 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02890 364816361f80a334c86b528d968067df 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 4.7E-69 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:1.20.120.330 785 918 2.3E-35 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Pfam PF08335 GlnD PII-uridylyltransferase 282 424 2.6E-37 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Pfam PF08335 GlnD PII-uridylyltransferase 800 904 1.2E-9 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 SUPERFAMILY SSF81301 7 269 3.92E-66 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 2 918 17.98 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:1.10.4050.10 506 622 2.8E-18 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:1.10.4050.10 7 87 5.3E-4 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:1.20.120.330 268 428 1.5E-41 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 SUPERFAMILY SSF81301 508 788 1.08E-68 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 7 244 6.6E-61 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 534 777 1.9E-63 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:3.30.460.10 88 267 3.8E-55 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 Gene3D G3DSA:3.30.460.10 623 784 1.1E-49 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 SUPERFAMILY SSF81593 788 916 1.8E-31 T 28-03-2018 AFA_RS11710 af60e6a6475cef004e2dcb162cc629da 918 SUPERFAMILY SSF81593 270 425 4.63E-35 T 28-03-2018 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 Pfam PF00593 TonB dependent receptor 360 800 1.9E-43 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 SUPERFAMILY SSF56935 122 802 6.92E-117 T 28-03-2018 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 Pfam PF07715 TonB-dependent Receptor Plug Domain 159 259 3.2E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 Gene3D G3DSA:2.170.130.10 119 267 6.1E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 SMART SM00965 68 118 9.4E-13 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 Pfam PF07660 Secretin and TonB N terminus short domain 68 117 2.8E-11 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 802 4.2E-96 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS16705 5ce5f5b554d8b72aa419adec511f680d 802 Gene3D G3DSA:2.40.170.20 270 802 2.5E-76 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 199 221 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 293 3.3E-52 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 Gene3D G3DSA:3.40.50.720 5 115 5.6E-27 T 28-03-2018 AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 319 3.7E-26 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 SUPERFAMILY SSF51735 104 294 8.74E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 SUPERFAMILY SSF52283 6 139 7.56E-31 T 28-03-2018 AFA_RS09435 6cf2106d8844ebd7bfa7cf73024e8350 323 Gene3D G3DSA:3.40.50.720 116 294 6.5E-47 T 28-03-2018 AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 Gene3D G3DSA:3.30.70.100 172 264 4.7E-22 T 28-03-2018 AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 SUPERFAMILY SSF50182 104 171 3.14E-13 T 28-03-2018 IPR010920 LSM domain AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 SUPERFAMILY SSF82861 19 103 1.57E-16 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 SUPERFAMILY SSF82689 172 268 4.71E-27 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 Pfam PF00924 Mechanosensitive ion channel 65 259 1.4E-47 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFA_RS04455 78f12765b155e632cdc342dc5fb158e0 277 Gene3D G3DSA:2.30.30.60 122 171 4.0E-11 T 28-03-2018 AFA_RS07185 7fbba936ed4882c8f91185cb1319c006 235 SUPERFAMILY SSF158682 76 230 9.81E-21 T 28-03-2018 AFA_RS07185 7fbba936ed4882c8f91185cb1319c006 235 Pfam PF04391 Protein of unknown function (DUF533) 41 229 7.4E-61 T 28-03-2018 IPR007486 Inner membrane protein YebE AFA_RS07185 7fbba936ed4882c8f91185cb1319c006 235 Gene3D G3DSA:1.10.3680.10 86 234 1.1E-12 T 28-03-2018 IPR029024 TerB-like AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 Pfam PF03466 LysR substrate binding domain 94 298 4.0E-32 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 Gene3D G3DSA:3.40.190.10 94 181 2.1E-11 T 28-03-2018 AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 Gene3D G3DSA:1.10.10.10 9 90 4.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 SUPERFAMILY SSF46785 10 117 6.67E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 SUPERFAMILY SSF53850 96 302 1.03E-36 T 28-03-2018 AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 Gene3D G3DSA:3.40.190.10 182 270 2.0E-14 T 28-03-2018 AFA_RS09485 b6c02ccdb17f6c3e516ff06c800609b7 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 3.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08475 a651ba7409a60e2d12b8d3fbd08bcb40 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 224 2.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08475 a651ba7409a60e2d12b8d3fbd08bcb40 232 SUPERFAMILY SSF161098 23 209 3.53E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08475 a651ba7409a60e2d12b8d3fbd08bcb40 232 Gene3D G3DSA:1.10.3720.10 4 229 4.3E-39 T 28-03-2018 AFA_RS08475 a651ba7409a60e2d12b8d3fbd08bcb40 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 25 115 1.5E-15 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS12575 e14d0805aed4d62c3a260a67371487da 76 Pfam PF04328 Selenoprotein, putative 19 76 1.1E-25 T 28-03-2018 IPR007423 Selenoprotein, putative AFA_RS01045 8957109b902fce6cfde37a06b77e477d 227 Gene3D G3DSA:1.10.3720.10 3 227 5.3E-44 T 28-03-2018 AFA_RS01045 8957109b902fce6cfde37a06b77e477d 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 224 2.1E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01045 8957109b902fce6cfde37a06b77e477d 227 SUPERFAMILY SSF161098 13 209 7.19E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01045 8957109b902fce6cfde37a06b77e477d 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 118 5.4E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 SUPERFAMILY SSF55347 161 323 4.76E-53 T 28-03-2018 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 Gene3D G3DSA:3.30.360.10 171 324 2.7E-48 T 28-03-2018 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 7 109 1.0E-32 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 166 321 1.8E-46 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 SMART SM00846 7 161 5.6E-66 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PIRSF PIRSF000149 5 343 6.7E-124 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 155 173 5.7E-19 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 5.7E-19 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 182 198 5.7E-19 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 239 256 5.7E-19 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 278 293 5.7E-19 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 SUPERFAMILY SSF51735 6 188 7.62E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 Gene3D G3DSA:3.40.50.720 4 170 1.6E-56 T 28-03-2018 AFA_RS09445 f8f9d9c0a2faab1ccf6dd5af1ea723af 347 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 159 166 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Pfam PF13599 Pentapeptide repeats (9 copies) 559 635 1.1E-6 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 37 293 5.7E-67 T 28-03-2018 IPR018683 Domain of unknown function DUF2169 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Gene3D G3DSA:2.160.10.20 639 703 2.9E-13 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Gene3D G3DSA:2.160.10.20 756 823 6.3E-9 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 SUPERFAMILY SSF141571 704 817 1.57E-21 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Pfam PF00805 Pentapeptide repeats (8 copies) 705 742 9.5E-8 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Pfam PF00805 Pentapeptide repeats (8 copies) 654 685 7.5E-8 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Gene3D G3DSA:2.160.20.80 539 638 2.7E-15 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 SUPERFAMILY SSF141571 552 702 5.62E-32 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Gene3D G3DSA:1.20.5.50 354 538 7.1E-4 T 28-03-2018 AFA_RS09925 3bbdbcc2e0aab1464fa58795e10f3a54 833 Gene3D G3DSA:2.160.10.20 704 755 2.7E-9 T 28-03-2018 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 275 134.395 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 SUPERFAMILY SSF55620 180 260 9.64E-10 T 28-03-2018 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 Pfam PF14489 QueF-like protein 189 264 1.7E-23 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 TIGRFAM TIGR03138 QueF: queuine synthase 7 275 7.6E-115 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 Gene3D G3DSA:3.30.1130.10 18 130 1.6E-33 T 28-03-2018 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 18 125 1.1E-40 T 28-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 Gene3D G3DSA:3.30.1130.10 138 275 2.2E-45 T 28-03-2018 AFA_RS11785 ce71b92dfc14896fed095fb2e0bc5892 275 PIRSF PIRSF004750 3 275 3.2E-113 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 SUPERFAMILY SSF53850 24 331 4.66E-72 T 28-03-2018 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 148 156 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 Gene3D G3DSA:3.40.190.10 130 334 6.6E-37 T 28-03-2018 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 Pfam PF13531 Bacterial extracellular solute-binding protein 38 284 6.0E-34 T 28-03-2018 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 23 331 1.8E-117 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 AFA_RS17245 899186dd677981fd6a08be7adbe55f1d 334 Gene3D G3DSA:3.40.190.10 23 129 6.7E-20 T 28-03-2018 AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 Gene3D G3DSA:3.40.50.1000 1 178 1.4E-30 T 28-03-2018 IPR023214 HAD-like domain AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 PIRSF PIRSF004682 1 179 1.6E-54 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 Pfam PF13242 HAD-hyrolase-like 99 153 1.6E-10 T 28-03-2018 AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 145 1.8E-43 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 146 9.5E-31 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AFA_RS03840 071c4dac5562bc4e6c8e2768a4be7481 179 SUPERFAMILY SSF56784 2 156 1.52E-44 T 28-03-2018 IPR023214 HAD-like domain AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 SUPERFAMILY SSF52540 3 221 1.7E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 Gene3D G3DSA:3.40.50.300 244 488 1.4E-28 T 28-03-2018 AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 SUPERFAMILY SSF52540 259 478 4.57E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 SMART SM00382 28 214 3.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 Pfam PF00005 ABC transporter 20 164 2.2E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 Pfam PF00005 ABC transporter 268 424 2.6E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 Gene3D G3DSA:3.40.50.300 1 242 5.2E-60 T 28-03-2018 AFA_RS14680 cff6afcdaf56beae5770b7e6069ce78e 504 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SUPERFAMILY SSF50249 652 737 6.49E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SMART SM00732 339 438 1.6E-34 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Gene3D G3DSA:1.10.3500.10 367 512 8.8E-39 T 28-03-2018 IPR023323 Tex-like domain AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Pfam PF16921 Tex protein YqgF-like domain 339 465 4.2E-51 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SUPERFAMILY SSF158832 12 334 9.15E-109 T 28-03-2018 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Pfam PF09371 Tex-like protein N-terminal domain 19 203 3.1E-66 T 28-03-2018 IPR018974 Tex-like protein, N-terminal AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SMART SM00316 663 734 3.0E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Gene3D G3DSA:2.40.50.140 657 739 8.6E-26 T 28-03-2018 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SUPERFAMILY SSF47781 575 646 2.89E-18 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Gene3D G3DSA:1.10.3500.10 113 366 3.0E-76 T 28-03-2018 IPR023323 Tex-like domain AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Pfam PF00575 S1 RNA binding domain 664 734 6.1E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Pfam PF12836 Helix-hairpin-helix motif 505 569 8.0E-27 T 28-03-2018 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Gene3D G3DSA:1.10.10.650 12 112 1.2E-31 T 28-03-2018 IPR023319 Tex-like protein, HTH domain AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 Gene3D G3DSA:1.10.150.310 513 644 5.4E-42 T 28-03-2018 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SUPERFAMILY SSF53098 335 483 2.73E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS04925 8d2a0f90097f9c5903ad78a0f755735c 782 SUPERFAMILY SSF47781 484 571 8.67E-28 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS15280 649dee584ccbfa0d22887707086f0a47 332 PIRSF PIRSF017082 1 332 8.9E-71 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS15280 649dee584ccbfa0d22887707086f0a47 332 SUPERFAMILY SSF53850 122 294 6.79E-6 T 28-03-2018 AFA_RS15280 649dee584ccbfa0d22887707086f0a47 332 Gene3D G3DSA:3.40.190.10 43 305 2.3E-8 T 28-03-2018 AFA_RS15280 649dee584ccbfa0d22887707086f0a47 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 326 8.9E-62 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 268 5.0E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 SUPERFAMILY SSF111369 48 252 1.12E-20 T 28-03-2018 AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 Gene3D G3DSA:2.40.50.100 59 120 1.0E-13 T 28-03-2018 AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 379 3.9E-47 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 Gene3D G3DSA:2.40.50.100 174 381 8.7E-5 T 28-03-2018 AFA_RS04405 9e871e13038fb4e5377f61c003dc015b 392 Gene3D G3DSA:1.10.287.470 121 173 3.7E-4 T 28-03-2018 AFA_RS14850 b2f23e7044ec8e76cad01e6180edf442 168 SUPERFAMILY SSF142433 5 164 1.57E-54 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS14850 b2f23e7044ec8e76cad01e6180edf442 168 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 13 164 5.3E-49 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS14850 b2f23e7044ec8e76cad01e6180edf442 168 Pfam PF02464 Competence-damaged protein 11 164 2.4E-56 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS14850 b2f23e7044ec8e76cad01e6180edf442 168 Gene3D G3DSA:3.90.950.20 1 168 7.1E-59 T 28-03-2018 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Pfam PF13167 GTP-binding GTPase N-terminal 18 104 4.4E-30 T 28-03-2018 IPR025121 GTPase HflX, N-terminal AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 PIRSF PIRSF006809 2 360 1.2E-135 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 1.0E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 1.0E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 213 231 1.0E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Pfam PF01926 50S ribosome-binding GTPase 192 310 3.9E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 SUPERFAMILY SSF52540 190 350 6.46E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 2.4E-30 T 28-03-2018 IPR032305 GTP-binding protein, middle domain AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Gene3D G3DSA:3.40.50.300 223 340 6.8E-16 T 28-03-2018 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Gene3D G3DSA:3.40.50.300 163 222 3.8E-12 T 28-03-2018 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 350 7.6E-148 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 AFA_RS11535 4f5e1b2433cea8de0d538df2118a7d13 362 Hamap MF_00900 GTPase HflX [hflX]. 19 361 45.273 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.206 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 3.0E-15 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 Gene3D G3DSA:2.40.50.100 20 84 2.5E-28 T 28-03-2018 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 Pfam PF01016 Ribosomal L27 protein 2 82 3.2E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 2.3E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15770 082cb0a2d683309a3a833d363f2e1d3e 86 SUPERFAMILY SSF110324 2 81 2.13E-32 T 28-03-2018 AFA_RS14915 04af96dad6477bce08043adbc8c09b76 904 Gene3D G3DSA:3.30.2090.10 593 699 0.37 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14915 04af96dad6477bce08043adbc8c09b76 904 Pfam PF05170 AsmA family 498 767 5.6E-23 T 28-03-2018 IPR007844 AsmA AFA_RS14915 04af96dad6477bce08043adbc8c09b76 904 Pfam PF05170 AsmA family 1 266 7.8E-27 T 28-03-2018 IPR007844 AsmA AFA_RS13040 78c669a2a1f8b07e502d8d826b24c4f5 301 TIGRFAM TIGR00688 rarD: protein RarD 3 258 2.6E-53 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 AFA_RS13040 78c669a2a1f8b07e502d8d826b24c4f5 301 SUPERFAMILY SSF103481 36 140 7.32E-7 T 28-03-2018 AFA_RS13040 78c669a2a1f8b07e502d8d826b24c4f5 301 Pfam PF00892 EamA-like transporter family 4 140 4.9E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 SUPERFAMILY SSF52317 546 689 5.57E-13 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 Pfam PF06628 Catalase-related immune-responsive 448 511 1.0E-20 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 360 368 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 ProSitePatterns PS00438 Catalase proximal active site signature. 66 82 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 SUPERFAMILY SSF56634 26 528 2.75E-216 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 43 66 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 315 342 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 347 373 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 106 124 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 146 164 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PRINTS PR00067 Catalase signature 127 144 7.1E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 Pfam PF00199 Catalase 30 415 6.0E-178 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 SMART SM01060 30 418 5.8E-267 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 Gene3D G3DSA:3.40.50.880 545 688 4.1E-9 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 Gene3D G3DSA:2.40.180.10 1 385 5.5E-161 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS12045 d17ec27ed74069f89107b796040e158e 691 PIRSF PIRSF038927 3 689 1.7E-293 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 SUPERFAMILY SSF54909 65 153 2.41E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.2E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.2E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.2E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 1.4E-18 T 28-03-2018 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 Gene3D G3DSA:3.30.70.920 58 155 1.7E-25 T 28-03-2018 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 SMART SM00344 5 114 7.1E-39 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 3.2E-20 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 SUPERFAMILY SSF46785 5 65 7.96E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17325 d317d20d647eef994aed52f6231d4547 162 Gene3D G3DSA:1.10.10.10 5 56 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10410 cfdff111ecaf25f9176df10ed89b0061 264 SUPERFAMILY SSF52540 2 233 7.78E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10410 cfdff111ecaf25f9176df10ed89b0061 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS10410 cfdff111ecaf25f9176df10ed89b0061 264 SMART SM00382 31 226 3.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS10410 cfdff111ecaf25f9176df10ed89b0061 264 Gene3D G3DSA:3.40.50.300 1 248 9.1E-53 T 28-03-2018 AFA_RS10410 cfdff111ecaf25f9176df10ed89b0061 264 Pfam PF00005 ABC transporter 22 177 2.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 Gene3D G3DSA:3.20.20.10 37 274 1.4E-61 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 Gene3D G3DSA:2.40.37.10 275 421 8.3E-42 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 52 285 3.2E-67 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 193 206 2.6E-24 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 92 2.6E-24 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 60 78 2.6E-24 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 276 295 2.6E-24 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 376 389 2.6E-24 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 376 2.0E-25 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 304 322 6.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 167 176 6.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 78 95 6.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 PRINTS PR01181 Diaminopimelate decarboxylase signature 386 408 6.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 18 419 41.192 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 SUPERFAMILY SSF51419 29 288 6.4E-78 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 231 244 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 418 6.2E-153 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS17905 9b4181638d51bb5a7bfefd469bd01f90 422 SUPERFAMILY SSF50621 263 420 2.09E-52 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Gene3D G3DSA:2.40.50.140 1 108 1.5E-27 T 28-03-2018 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Pfam PF02938 GAD domain 308 406 9.4E-26 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 588 4.4E-240 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 590 33.351 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 564 2.3E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 SUPERFAMILY SSF55261 291 416 4.14E-40 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 1.3E-19 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 2.8E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 524 538 2.8E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 480 496 2.8E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 2.8E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 SUPERFAMILY SSF50249 1 105 4.19E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 SUPERFAMILY SSF55681 430 590 7.96E-103 T 28-03-2018 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 SUPERFAMILY SSF55681 110 292 7.96E-103 T 28-03-2018 AFA_RS17615 ab5329578a258c7b41e2b6832018c33b 595 Gene3D G3DSA:3.30.930.10 132 592 2.7E-105 T 28-03-2018 AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 Pfam PF00107 Zinc-binding dehydrogenase 159 271 4.5E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 SUPERFAMILY SSF51735 118 289 3.08E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 Gene3D G3DSA:3.40.50.720 150 267 1.0E-12 T 28-03-2018 AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 SUPERFAMILY SSF50129 3 146 1.22E-43 T 28-03-2018 IPR011032 GroES-like AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 4 326 2.3E-136 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 Gene3D G3DSA:3.90.180.10 1 149 4.0E-28 T 28-03-2018 AFA_RS15285 1cf51067fb23cad29fe641ffa2dcafe3 328 SMART SM00829 12 324 7.4E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Gene3D G3DSA:3.40.1110.10 319 439 3.0E-22 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 306 312 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Pfam PF00122 E1-E2 ATPase 99 283 4.3E-35 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 11 674 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF56784 432 556 4.76E-38 T 28-03-2018 IPR023214 HAD-like domain AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF56784 292 316 4.76E-38 T 28-03-2018 IPR023214 HAD-like domain AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF56784 369 401 4.76E-38 T 28-03-2018 IPR023214 HAD-like domain AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF81653 106 200 1.31E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 527 1.2E-34 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 677 40.163 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Gene3D G3DSA:3.40.50.1000 440 572 1.3E-34 T 28-03-2018 IPR023214 HAD-like domain AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF81665 23 96 1.7E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 SUPERFAMILY SSF81665 201 298 1.7E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 470 3.6E-24 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 548 3.6E-24 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 532 3.6E-24 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 147 161 3.6E-24 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 3.6E-24 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 Gene3D G3DSA:1.20.1110.10 56 318 5.5E-28 T 28-03-2018 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 65 335 4.9E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS07305 fff1c4e4d9cae2a334dbed187e60b849 678 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 369 598 2.5E-46 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS18355 17c67baa825ca103433504f3de2454ed 174 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 27.112 T 28-03-2018 IPR022973 Ribosomal protein L10 AFA_RS18355 17c67baa825ca103433504f3de2454ed 174 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18355 17c67baa825ca103433504f3de2454ed 174 Pfam PF00466 Ribosomal protein L10 4 100 8.2E-24 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AFA_RS18355 17c67baa825ca103433504f3de2454ed 174 SUPERFAMILY SSF160369 3 171 9.29E-56 T 28-03-2018 AFA_RS18355 17c67baa825ca103433504f3de2454ed 174 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 25 159 2.0E-4 T 28-03-2018 AFA_RS16540 045c432f7d434b72c7fbcfdb47221353 270 Pfam PF00535 Glycosyl transferase family 2 3 131 1.2E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS16540 045c432f7d434b72c7fbcfdb47221353 270 SUPERFAMILY SSF53448 2 225 7.74E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16540 045c432f7d434b72c7fbcfdb47221353 270 Gene3D G3DSA:3.90.550.10 1 263 3.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS14865 67a7b45e0a67531a6eb57d1d8db623e3 171 Gene3D G3DSA:1.10.940.10 23 164 2.2E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFA_RS14865 67a7b45e0a67531a6eb57d1d8db623e3 171 Pfam PF01029 NusB family 30 157 3.4E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFA_RS14865 67a7b45e0a67531a6eb57d1d8db623e3 171 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 28 159 3.0E-34 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 AFA_RS14865 67a7b45e0a67531a6eb57d1d8db623e3 171 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 26 161 19.889 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 AFA_RS14865 67a7b45e0a67531a6eb57d1d8db623e3 171 SUPERFAMILY SSF48013 26 161 1.57E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFA_RS11345 f2c04b7b2964feebfb57c9025dfb64df 677 Gene3D G3DSA:1.20.140.50 32 676 2.8E-8 T 28-03-2018 AFA_RS11345 f2c04b7b2964feebfb57c9025dfb64df 677 Pfam PF13598 Domain of unknown function (DUF4139) 221 501 1.7E-14 T 28-03-2018 IPR011935 Conserved hypothetical protein CHP02231 AFA_RS00255 b1fcd1f8f47b6604fde91ea2b6f77275 501 Gene3D G3DSA:3.40.920.10 1 211 2.3E-35 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS00255 b1fcd1f8f47b6604fde91ea2b6f77275 501 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 203 9.2E-11 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS00255 b1fcd1f8f47b6604fde91ea2b6f77275 501 SUPERFAMILY SSF53323 6 214 1.01E-5 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFA_RS14550 83f7d91385f1c46365cb851a230a11b8 103 Pfam PF05164 Cell division protein ZapA 4 88 2.4E-20 T 28-03-2018 IPR007838 Cell division protein ZapA-like AFA_RS14550 83f7d91385f1c46365cb851a230a11b8 103 SUPERFAMILY SSF102829 3 95 1.7E-19 T 28-03-2018 IPR007838 Cell division protein ZapA-like AFA_RS07215 f8db651444f565050435ef8539cf082b 289 Pfam PF03476 MOSC N-terminal beta barrel domain 1 120 3.9E-31 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel AFA_RS07215 f8db651444f565050435ef8539cf082b 289 SUPERFAMILY SSF141673 4 134 9.29E-36 T 28-03-2018 AFA_RS07215 f8db651444f565050435ef8539cf082b 289 Pfam PF03473 MOSC domain 160 280 3.8E-18 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 AFA_RS07215 f8db651444f565050435ef8539cf082b 289 SUPERFAMILY SSF50800 2 51 2.93E-6 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain AFA_RS07215 f8db651444f565050435ef8539cf082b 289 SUPERFAMILY SSF50800 167 244 2.93E-6 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain AFA_RS07215 f8db651444f565050435ef8539cf082b 289 Gene3D G3DSA:2.40.33.20 1 288 4.1E-33 T 28-03-2018 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 Pfam PF00196 Bacterial regulatory proteins, luxR family 233 288 3.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 Gene3D G3DSA:1.10.10.10 129 298 4.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 264 276 1.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 248 264 1.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 234 248 1.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 SUPERFAMILY SSF46894 224 293 4.42E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS08305 cd49fd5c9d7047c315ee1694a3ad6e32 311 SMART SM00421 231 288 7.8E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08705 56f050bc196e6d442723de0540bba17c 412 Pfam PF07690 Major Facilitator Superfamily 25 369 1.8E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS08705 56f050bc196e6d442723de0540bba17c 412 Gene3D G3DSA:1.20.1250.20 13 211 8.0E-23 T 28-03-2018 AFA_RS08705 56f050bc196e6d442723de0540bba17c 412 Gene3D G3DSA:1.20.1250.20 212 405 8.4E-19 T 28-03-2018 AFA_RS08705 56f050bc196e6d442723de0540bba17c 412 SUPERFAMILY SSF103473 17 405 1.03E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS14705 d3a1685868d434d0242942de797faa73 302 Gene3D G3DSA:3.40.190.10 177 262 4.1E-15 T 28-03-2018 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 Gene3D G3DSA:1.10.10.10 1 87 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14705 d3a1685868d434d0242942de797faa73 302 SUPERFAMILY SSF53850 90 294 1.05E-32 T 28-03-2018 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 SUPERFAMILY SSF46785 1 85 1.32E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14705 d3a1685868d434d0242942de797faa73 302 Gene3D G3DSA:3.40.190.10 88 176 1.5E-10 T 28-03-2018 AFA_RS14705 d3a1685868d434d0242942de797faa73 302 Pfam PF03466 LysR substrate binding domain 88 291 1.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 Gene3D G3DSA:1.20.1640.10 389 604 2.6E-29 T 28-03-2018 AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 Pfam PF07549 SecD/SecF GG Motif 126 151 8.4E-7 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 134 598 1.8E-144 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 612 48.222 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 357 591 1.7E-73 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 SUPERFAMILY SSF82866 408 605 3.27E-40 T 28-03-2018 AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 Pfam PF13721 SecD export protein N-terminal TM region 1 114 5.5E-34 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain AFA_RS03240 4d58ba0a3bd72eba6c662c455f552bee 623 Pfam PF02355 Protein export membrane protein 431 598 5.3E-20 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 148 9.6E-38 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 SUPERFAMILY SSF51735 8 180 6.72E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 SUPERFAMILY SSF55347 156 320 4.45E-49 T 28-03-2018 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 9 346 41.402 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 Gene3D G3DSA:3.40.50.720 2 165 1.5E-47 T 28-03-2018 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 SMART SM00859 10 148 4.7E-59 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 9 352 5.4E-129 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 Gene3D G3DSA:3.30.360.10 166 320 1.0E-56 T 28-03-2018 AFA_RS15525 cb236fb2fb3ba1d7b92b7c920da9f466 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 165 323 1.4E-17 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 SUPERFAMILY SSF103515 623 936 2.22E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 406 437 1.7E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 2.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 PRINTS PR00723 Subtilisin serine protease family (S8) signature 62 81 2.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 PRINTS PR00723 Subtilisin serine protease family (S8) signature 320 336 2.5E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 321 331 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 Pfam PF03797 Autotransporter beta-domain 661 917 2.1E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 Gene3D G3DSA:2.40.128.130 613 936 1.3E-52 T 28-03-2018 AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 469 935 1.9E-36 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 Pfam PF00082 Subtilase family 62 368 1.1E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 Gene3D G3DSA:3.40.50.200 30 386 4.1E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 Pfam PF12951 Passenger-associated-transport-repeat 407 436 2.1E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 SMART SM00869 658 927 4.5E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16285 1f300fa0140dfe2868db01c4670a8987 936 SUPERFAMILY SSF52743 44 382 4.97E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS15115 afb05d860d79f35719fad8486d3abf87 172 Gene3D G3DSA:3.10.450.50 9 172 3.6E-27 T 28-03-2018 AFA_RS15115 afb05d860d79f35719fad8486d3abf87 172 SUPERFAMILY SSF54427 18 170 1.39E-37 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS15115 afb05d860d79f35719fad8486d3abf87 172 Pfam PF00866 Ring hydroxylating beta subunit 34 164 1.9E-11 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 Gene3D G3DSA:3.40.190.10 179 254 7.3E-11 T 28-03-2018 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 Gene3D G3DSA:1.10.10.10 2 91 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04255 615586072627c66e7665654730b1b0ee 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 Pfam PF03466 LysR substrate binding domain 88 291 1.4E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS04255 615586072627c66e7665654730b1b0ee 301 SUPERFAMILY SSF46785 4 88 3.92E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04255 615586072627c66e7665654730b1b0ee 301 Gene3D G3DSA:3.40.190.10 92 178 3.0E-15 T 28-03-2018 AFA_RS04255 615586072627c66e7665654730b1b0ee 301 SUPERFAMILY SSF53850 89 294 1.81E-32 T 28-03-2018 AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 SMART SM00470 41 134 2.5E-33 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 Gene3D G3DSA:1.10.10.730 135 182 5.0E-21 T 28-03-2018 AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 Gene3D G3DSA:3.90.1530.10 30 134 7.4E-34 T 28-03-2018 AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 Pfam PF02195 ParB-like nuclease domain 43 134 2.4E-24 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 SUPERFAMILY SSF109709 127 233 7.85E-34 T 28-03-2018 AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 SUPERFAMILY SSF110849 43 136 2.88E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS18405 1c664b8d5c17ff44d2a0530f60eb02d8 312 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 41 216 5.0E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFA_RS10445 1ace938872b20be6a9b2385e43799909 261 SUPERFAMILY SSF51621 8 252 4.93E-55 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS10445 1ace938872b20be6a9b2385e43799909 261 Gene3D G3DSA:3.20.20.60 4 259 5.5E-48 T 28-03-2018 AFA_RS10445 1ace938872b20be6a9b2385e43799909 261 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 243 3.8E-62 T 28-03-2018 AFA_RS17115 81e76180bd1c299b0526bfea365f7dbf 263 Pfam PF00005 ABC transporter 37 178 3.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS17115 81e76180bd1c299b0526bfea365f7dbf 263 Gene3D G3DSA:3.40.50.300 1 258 7.8E-64 T 28-03-2018 AFA_RS17115 81e76180bd1c299b0526bfea365f7dbf 263 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS17115 81e76180bd1c299b0526bfea365f7dbf 263 SMART SM00382 45 225 4.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS17115 81e76180bd1c299b0526bfea365f7dbf 263 SUPERFAMILY SSF52540 31 241 5.33E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 SUPERFAMILY SSF160996 190 347 2.62E-35 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 399 4.5E-117 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 Gene3D G3DSA:1.10.8.260 274 329 3.5E-16 T 28-03-2018 IPR023166 HI0933 insert-like domain AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 318 334 1.3E-6 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.3E-6 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.3E-6 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-6 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 SUPERFAMILY SSF51905 5 189 5.41E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 SUPERFAMILY SSF51905 345 402 5.41E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 Gene3D G3DSA:2.40.30.10 189 273 3.5E-23 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 Gene3D G3DSA:3.50.50.60 5 180 7.8E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 Pfam PF03486 HI0933-like protein 5 400 2.9E-133 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 1.1E-8 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 322 329 1.1E-8 T 28-03-2018 AFA_RS02585 c5fc20f9ce113b51fdb749e4547773bf 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.1E-8 T 28-03-2018 AFA_RS02310 32b8fb6d90710e602f0da8f7259d43df 153 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 144 1.1E-46 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 AFA_RS02310 32b8fb6d90710e602f0da8f7259d43df 153 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.574 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 Pfam PF04055 Radical SAM superfamily 74 243 4.5E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 SUPERFAMILY SSF102114 21 461 5.23E-129 T 28-03-2018 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 Gene3D G3DSA:3.20.20.70 52 370 1.3E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 19 473 1.4E-175 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 SMART SM00729 68 289 5.2E-49 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 Pfam PF06969 HemN C-terminal domain 382 448 3.2E-12 T 28-03-2018 IPR010723 HemN, C-terminal AFA_RS11095 7ba5ddbbbd95af75e0087a31b4856ec1 473 PIRSF PIRSF000167 17 471 1.4E-163 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 502 1.9E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 350 374 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 441 462 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 321 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 347 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 402 418 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 476 494 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 6.6E-63 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 466 488 3.0E-40 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 3.0E-40 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 439 455 3.0E-40 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 372 3.0E-40 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 330 3.0E-40 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Gene3D G3DSA:3.40.30.10 104 197 3.9E-9 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Gene3D G3DSA:3.50.50.60 339 442 5.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 SUPERFAMILY SSF51905 204 513 2.03E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 342 362 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Gene3D G3DSA:3.50.50.60 207 338 2.6E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Pfam PF13192 Thioredoxin domain 125 195 6.5E-10 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 SUPERFAMILY SSF52833 104 197 1.4E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Gene3D G3DSA:3.50.50.60 443 530 2.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 515 4.0E-241 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 Gene3D G3DSA:3.40.30.10 1 94 3.3E-28 T 28-03-2018 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 PIRSF PIRSF000238 1 519 5.7E-257 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 AFA_RS14715 3f0ea860a9951fd6df6a83144827fea6 530 SUPERFAMILY SSF52833 1 101 5.03E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS07355 655423c4f705cf92a7ab89f10c82e749 254 Gene3D G3DSA:3.90.550.10 1 254 1.1E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS07355 655423c4f705cf92a7ab89f10c82e749 254 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 251 41.082 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AFA_RS07355 655423c4f705cf92a7ab89f10c82e749 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 244 5.3E-84 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AFA_RS07355 655423c4f705cf92a7ab89f10c82e749 254 Pfam PF02348 Cytidylyltransferase 5 222 4.6E-56 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 AFA_RS07355 655423c4f705cf92a7ab89f10c82e749 254 SUPERFAMILY SSF53448 1 253 5.63E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 370 7.7E-120 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 Gene3D G3DSA:1.20.1090.10 185 382 3.4E-65 T 28-03-2018 AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 Gene3D G3DSA:3.40.50.1970 10 183 1.0E-46 T 28-03-2018 AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 SUPERFAMILY SSF56796 5 379 1.7E-125 T 28-03-2018 AFA_RS04760 4b4a0b99e85d54dfcd10b69e43567d36 382 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 PIRSF PIRSF000190 1 210 5.3E-81 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 169 210 2.3E-19 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 SUPERFAMILY SSF50475 15 210 4.13E-62 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 Gene3D G3DSA:2.30.110.10 9 210 1.7E-69 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 118 1.8E-23 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 179 192 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 210 2.5E-83 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS03495 d1a6c7c7a6421ffec653e8e57da61d59 210 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 210 37.479 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 SUPERFAMILY SSF50249 12 153 5.88E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 506 43.712 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 260 277 2.9E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 388 404 2.9E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 213 229 2.9E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 242 255 2.9E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 207 2.9E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 Gene3D G3DSA:2.40.50.140 14 153 4.9E-42 T 28-03-2018 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 SUPERFAMILY SSF55681 160 504 3.06E-113 T 28-03-2018 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 Gene3D G3DSA:3.30.930.10 154 503 9.3E-97 T 28-03-2018 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 160 503 1.9E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 Pfam PF01336 OB-fold nucleic acid binding domain 67 144 9.2E-17 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFA_RS07740 a574ba2f4f09e4e8edef3cd3a355cd61 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 505 3.6E-199 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 Pfam PF17384 RimP C-terminal SH3 domain 81 154 8.8E-9 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 Pfam PF02576 RimP N-terminal domain 8 74 8.4E-14 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 SUPERFAMILY SSF74942 75 156 1.57E-10 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 Gene3D G3DSA:3.30.300.70 1 71 8.3E-17 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 Gene3D G3DSA:2.30.30.180 80 153 4.8E-14 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 SUPERFAMILY SSF75420 3 74 1.26E-14 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFA_RS05090 eaceb9515d113617574857ffa0401fa6 163 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 2 156 19.042 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 594 4.3E-238 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 SUPERFAMILY SSF140990 404 600 9.94E-76 T 28-03-2018 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 4 610 37.264 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Gene3D G3DSA:1.10.8.60 335 411 7.2E-27 T 28-03-2018 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 SUPERFAMILY SSF52540 146 393 7.57E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 1.0E-44 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Gene3D G3DSA:3.40.50.300 134 334 3.2E-61 T 28-03-2018 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 SMART SM00382 186 325 3.5E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Pfam PF06480 FtsH Extracellular 10 78 7.6E-7 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 AFA_RS04170 f42260a2c5d670587d1bed01e6faabd8 637 Pfam PF01434 Peptidase family M41 384 592 7.5E-81 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 Pfam PF00425 chorismate binding enzyme 226 487 9.8E-96 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 177 2.1E-28 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 Gene3D G3DSA:3.60.120.10 13 497 1.5E-161 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 SUPERFAMILY SSF56322 14 495 7.46E-153 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 PRINTS PR00095 Anthranilate synthase component I signature 444 458 2.0E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 PRINTS PR00095 Anthranilate synthase component I signature 349 362 2.0E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 PRINTS PR00095 Anthranilate synthase component I signature 335 348 2.0E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 PRINTS PR00095 Anthranilate synthase component I signature 429 443 2.0E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01360 e55528e4807aa7fc741e02986175db54 506 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 495 5.5E-159 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS10395 f46e69d3169e1010caa4534eea61b070 487 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 467 2.5E-115 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS10395 f46e69d3169e1010caa4534eea61b070 487 SUPERFAMILY SSF56954 3 469 9.42E-110 T 28-03-2018 AFA_RS10395 f46e69d3169e1010caa4534eea61b070 487 Gene3D G3DSA:1.20.1600.10 21 473 4.0E-100 T 28-03-2018 AFA_RS10395 f46e69d3169e1010caa4534eea61b070 487 Pfam PF02321 Outer membrane efflux protein 66 257 2.7E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS10395 f46e69d3169e1010caa4534eea61b070 487 Pfam PF02321 Outer membrane efflux protein 285 465 3.1E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS13160 b323b4838922c497bd3ef31bf0b2d838 317 Gene3D G3DSA:3.90.420.10 39 277 9.1E-63 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS13160 b323b4838922c497bd3ef31bf0b2d838 317 Pfam PF00174 Oxidoreductase molybdopterin binding domain 97 252 8.0E-33 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS13160 b323b4838922c497bd3ef31bf0b2d838 317 SUPERFAMILY SSF56524 68 313 1.7E-92 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS13160 b323b4838922c497bd3ef31bf0b2d838 317 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 317 53.963 T 28-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 417 436 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 SUPERFAMILY SSF56645 72 293 6.62E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 SUPERFAMILY SSF47203 301 462 6.93E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 Gene3D G3DSA:2.40.110.10 185 292 4.4E-15 T 28-03-2018 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 303 458 7.5E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 191 291 8.3E-10 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS07990 cb83bea69d8da1396e36ce9c0680bbc3 570 Gene3D G3DSA:1.20.140.10 293 468 4.1E-37 T 28-03-2018 AFA_RS11120 1376ede434fc10040555cfa35b888390 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 34 85 1.0E-19 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AFA_RS11120 1376ede434fc10040555cfa35b888390 93 PIRSF PIRSF028784 1 93 4.0E-26 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 SUPERFAMILY SSF56645 6 247 3.01E-88 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 PIRSF PIRSF016578 16 105 0.047 T 28-03-2018 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 PIRSF PIRSF016578 135 392 2.3E-11 T 28-03-2018 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.1E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Gene3D G3DSA:1.10.540.10 2 125 1.8E-41 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Gene3D G3DSA:2.40.110.10 126 222 2.2E-42 T 28-03-2018 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 123 2.8E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 387 2.8E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 Gene3D G3DSA:1.20.140.10 223 392 6.1E-51 T 28-03-2018 AFA_RS00690 e32cd01749a9ef7c160e025e7a8c8aed 392 SUPERFAMILY SSF47203 233 388 2.42E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 PIRSF PIRSF002741 13 531 8.1E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 Gene3D G3DSA:3.90.76.10 61 153 1.9E-24 T 28-03-2018 AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 SUPERFAMILY SSF53850 35 526 3.08E-96 T 28-03-2018 AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 450 8.4E-74 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 Gene3D G3DSA:3.40.190.10 154 303 5.8E-29 T 28-03-2018 AFA_RS08905 bf3c149cb3a002d58dd9605bd0bafc28 532 Gene3D G3DSA:3.10.105.10 304 504 5.9E-28 T 28-03-2018 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 SUPERFAMILY SSF46689 451 503 2.73E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 467 484 9.7E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 484 504 9.7E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Gene3D G3DSA:3.30.450.40 5 164 7.3E-10 T 28-03-2018 IPR029016 GAF domain-like AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 SUPERFAMILY SSF52540 184 418 3.07E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 SUPERFAMILY SSF55781 19 165 1.98E-9 T 28-03-2018 IPR029016 GAF domain-like AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Gene3D G3DSA:3.40.50.300 179 356 1.1E-27 T 28-03-2018 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Gene3D G3DSA:1.10.8.60 357 460 5.8E-22 T 28-03-2018 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 397 406 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 270 285 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 208 221 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Pfam PF02954 Bacterial regulatory protein, Fis family 461 495 9.2E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Gene3D G3DSA:1.10.10.60 461 508 6.0E-13 T 28-03-2018 AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 SMART SM00382 204 347 8.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15965 5588949482f16ce0f9fdfdfef9aca450 513 Pfam PF00158 Sigma-54 interaction domain 184 350 1.4E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS16785 944c201e3b42308bc642afc7ebe0fa50 702 Gene3D G3DSA:2.170.130.10 25 170 2.9E-8 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16785 944c201e3b42308bc642afc7ebe0fa50 702 Gene3D G3DSA:2.40.170.20 171 702 3.9E-65 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16785 944c201e3b42308bc642afc7ebe0fa50 702 SUPERFAMILY SSF56935 76 702 1.39E-82 T 28-03-2018 AFA_RS16785 944c201e3b42308bc642afc7ebe0fa50 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 166 1.1E-5 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16785 944c201e3b42308bc642afc7ebe0fa50 702 Pfam PF00593 TonB dependent receptor 239 701 4.7E-44 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SUPERFAMILY SSF48334 272 581 3.4E-86 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 866 24.258 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Gene3D G3DSA:3.40.1170.10 1 134 1.7E-42 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Pfam PF05192 MutS domain III 275 574 8.6E-40 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SUPERFAMILY SSF53150 120 285 4.97E-35 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Gene3D G3DSA:1.10.1420.10 423 550 3.1E-31 T 28-03-2018 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 702 718 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Pfam PF00488 MutS domain V 625 811 1.4E-80 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 PIRSF PIRSF037677 3 201 2.5E-23 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 PIRSF PIRSF037677 204 856 1.2E-122 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Pfam PF05188 MutS domain II 133 257 4.2E-19 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Pfam PF05190 MutS family domain IV 443 534 2.6E-29 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Gene3D G3DSA:3.30.420.110 135 267 5.5E-25 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Gene3D G3DSA:3.40.50.300 582 849 4.4E-40 T 28-03-2018 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Pfam PF01624 MutS domain I 11 122 1.2E-39 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 Gene3D G3DSA:1.10.1420.10 268 422 1.2E-34 T 28-03-2018 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SMART SM00534 621 808 1.0E-109 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SUPERFAMILY SSF55271 6 118 1.83E-40 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 872 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SUPERFAMILY SSF52540 582 811 9.46E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04390 d5330876c4a67b96f18c3db0775f4e14 878 SMART SM00533 288 606 2.2E-90 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFA_RS10330 12d885822aed088f773a76587f9034f9 189 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 49 170 1.1E-32 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 3 461 32.589 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 SUPERFAMILY SSF53697 4 483 1.05E-144 T 28-03-2018 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Gene3D G3DSA:1.10.1390.10 449 484 1.2E-16 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Pfam PF00342 Phosphoglucose isomerase 15 477 1.4E-137 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 434 451 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 420 434 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 434 447 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 90 109 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 402 420 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 PRINTS PR00662 Glucose-6-phosphate isomerase signature 276 297 2.3E-43 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Gene3D G3DSA:3.40.50.10490 1 85 4.9E-9 T 28-03-2018 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Gene3D G3DSA:3.40.50.10490 86 196 1.7E-30 T 28-03-2018 AFA_RS16940 0f77f539a52a7e4d4a10ee2399b89cb8 484 Gene3D G3DSA:3.40.50.10490 197 448 1.0E-99 T 28-03-2018 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 21 126 2.0E-38 T 28-03-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SUPERFAMILY SSF158472 155 204 2.35E-6 T 28-03-2018 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SMART SM00388 208 267 1.8E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SUPERFAMILY SSF55874 273 421 1.44E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SMART SM00304 155 207 1.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SMART SM00387 309 424 1.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Gene3D G3DSA:1.10.287.130 198 263 1.2E-8 T 28-03-2018 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 421 5.0E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 SUPERFAMILY SSF47384 192 263 1.53E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 421 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Pfam PF00672 HAMP domain 155 203 3.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Gene3D G3DSA:3.30.565.10 270 430 1.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS13315 e0743ec91ade247c30634544f0658a18 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 264 6.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS04845 b514c9cbcf50dd166d9fa72145a15840 137 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 7 131 3.8E-36 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04845 b514c9cbcf50dd166d9fa72145a15840 137 SUPERFAMILY SSF81343 7 133 2.62E-26 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04845 b514c9cbcf50dd166d9fa72145a15840 137 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 17 129 8.7E-27 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04845 b514c9cbcf50dd166d9fa72145a15840 137 PIRSF PIRSF000178 2 134 2.2E-26 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04845 b514c9cbcf50dd166d9fa72145a15840 137 Gene3D G3DSA:1.20.1300.10 22 136 2.3E-24 T 28-03-2018 AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 Gene3D G3DSA:1.10.10.10 1 74 6.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 SMART SM00895 101 231 3.7E-18 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 Gene3D G3DSA:1.20.120.530 94 249 7.9E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 3.9E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 SUPERFAMILY SSF46785 3 76 6.82E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 Pfam PF07729 FCD domain 101 230 5.8E-21 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 SUPERFAMILY SSF48008 100 237 2.88E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS04875 eda7f5977100720f0c4c194352dbca20 259 SMART SM00345 13 72 9.6E-24 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:3.50.50.60 357 455 1.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:3.50.50.60 238 356 4.6E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 382 398 2.1E-37 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 145 2.1E-37 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 2.1E-37 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 411 433 2.1E-37 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 312 2.1E-37 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 526 541 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 147 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 173 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 268 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 461 482 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 319 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 433 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 548 568 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 397 1.2E-68 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 SUPERFAMILY SSF51230 2 96 1.26E-23 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 SUPERFAMILY SSF55424 461 583 4.98E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:3.30.390.30 456 581 3.7E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Pfam PF00364 Biotin-requiring enzyme 5 76 2.9E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:1.10.287.990 170 224 1.1E-19 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 PIRSF PIRSF000350 30 583 6.7E-84 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:2.40.50.100 13 64 4.3E-15 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 SUPERFAMILY SSF51905 121 456 3.27E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 124 579 7.0E-148 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 465 573 1.4E-34 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:3.50.50.60 117 169 3.8E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 125 446 4.7E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 Gene3D G3DSA:3.90.1170.30 65 101 2.7E-4 T 28-03-2018 AFA_RS10260 7ddd6ba6767d803ee6e6feb5a1af135b 590 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 159 169 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 Pfam PF00905 Penicillin binding protein transpeptidase domain 255 550 9.8E-68 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 213 2.3E-20 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 SUPERFAMILY SSF56601 180 564 1.13E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 SUPERFAMILY SSF56519 60 228 6.28E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 Gene3D G3DSA:3.40.710.10 230 573 6.4E-78 T 28-03-2018 AFA_RS03640 027b699f22c3fd6716dd80d5ad4b21c0 579 Gene3D G3DSA:3.90.1310.10 33 229 5.8E-42 T 28-03-2018 AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 SUPERFAMILY SSF50685 89 179 8.72E-10 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 SUPERFAMILY SSF110997 283 358 3.27E-12 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 Pfam PF05036 Sporulation related domain 285 358 1.2E-12 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 Gene3D G3DSA:2.40.40.10 80 190 6.6E-24 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 Gene3D G3DSA:3.30.70.1070 280 360 1.4E-11 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 11 190 23.909 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 Pfam PF03330 Lytic transglycolase 97 187 1.0E-25 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFA_RS16370 615e86a5695e0810c3d96ad0d99c0ea7 361 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 100 215 5.3E-41 T 28-03-2018 IPR012997 Rare lipoprotein A AFA_RS02970 49da3a0da7708e3cec0562d2267519eb 273 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 238 259 3.8E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS02970 49da3a0da7708e3cec0562d2267519eb 273 Pfam PF00005 ABC transporter 34 190 3.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02970 49da3a0da7708e3cec0562d2267519eb 273 SMART SM00382 42 262 2.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02970 49da3a0da7708e3cec0562d2267519eb 273 Gene3D G3DSA:3.40.50.300 2 271 3.9E-52 T 28-03-2018 AFA_RS02970 49da3a0da7708e3cec0562d2267519eb 273 SUPERFAMILY SSF52540 17 260 2.33E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 SMART SM00346 2 92 2.4E-27 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 Gene3D G3DSA:3.30.450.40 89 249 3.2E-52 T 28-03-2018 IPR029016 GAF domain-like AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 SUPERFAMILY SSF46785 4 75 5.99E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 Pfam PF09339 IclR helix-turn-helix domain 7 54 1.2E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 Gene3D G3DSA:1.10.10.10 6 88 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 Pfam PF01614 Bacterial transcriptional regulator 120 242 1.3E-30 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS15300 ec07fc61ae3b5e29d5c34181e7d74d09 249 SUPERFAMILY SSF55781 67 246 4.45E-51 T 28-03-2018 IPR029016 GAF domain-like AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 Gene3D G3DSA:3.40.47.10 292 423 2.3E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 424 1.7E-126 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 SUPERFAMILY SSF53901 288 424 8.53E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 ProSitePatterns PS00737 Thiolases signature 2. 372 388 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 SUPERFAMILY SSF53901 6 287 4.42E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 Gene3D G3DSA:3.40.47.10 2 291 1.2E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 ProSitePatterns PS00099 Thiolases active site. 407 420 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 PIRSF PIRSF000429 1 427 7.4E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 Pfam PF00108 Thiolase, N-terminal domain 6 279 6.2E-58 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS18150 e0b0fb6b1167da32885bdef98c4d30b8 431 Pfam PF02803 Thiolase, C-terminal domain 287 424 4.2E-39 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS12505 17e79e82b7a6bd3bb075c5dd9d68ec0d 548 SUPERFAMILY SSF56112 99 160 4.89E-28 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS12505 17e79e82b7a6bd3bb075c5dd9d68ec0d 548 SUPERFAMILY SSF56112 194 425 4.89E-28 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS12505 17e79e82b7a6bd3bb075c5dd9d68ec0d 548 Pfam PF03109 ABC1 family 116 232 9.5E-32 T 28-03-2018 IPR004147 UbiB domain AFA_RS12505 17e79e82b7a6bd3bb075c5dd9d68ec0d 548 Gene3D G3DSA:1.10.510.10 251 364 6.7E-4 T 28-03-2018 AFA_RS12505 17e79e82b7a6bd3bb075c5dd9d68ec0d 548 Gene3D G3DSA:3.30.200.20 104 245 4.9E-22 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 SUPERFAMILY SSF141571 13 128 3.01E-26 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Gene3D G3DSA:2.160.10.20 144 230 2.2E-13 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Gene3D G3DSA:2.160.10.20 231 306 1.0E-11 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 SUPERFAMILY SSF141571 138 292 1.88E-24 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Pfam PF00805 Pentapeptide repeats (8 copies) 229 267 1.4E-5 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Pfam PF00805 Pentapeptide repeats (8 copies) 158 188 0.0054 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Gene3D G3DSA:2.160.20.80 1 143 1.9E-25 T 28-03-2018 AFA_RS09920 c86583788be9b8cb23083568b799923c 318 Pfam PF13599 Pentapeptide repeats (9 copies) 59 127 3.8E-10 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 643 3.8E-24 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 3 651 43.485 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 SUPERFAMILY SSF54211 222 397 1.8E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Gene3D G3DSA:3.40.50.670 405 650 2.1E-78 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 SMART SM00387 28 177 7.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Gene3D G3DSA:3.30.230.10 221 401 2.7E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Pfam PF01751 Toprim domain 423 537 2.3E-12 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS11680 605605f3032e7347428b104ab559bfec 653 SUPERFAMILY SSF56719 399 644 1.05E-75 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 511 528 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 113 127 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 67 80 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 531 543 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 32 47 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 424 438 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 276 289 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 583 599 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR00418 DNA topoisomerase II family signature 493 509 7.5E-61 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 175 3.4E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11680 605605f3032e7347428b104ab559bfec 653 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 SMART SM00433 34 647 6.6E-187 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 SUPERFAMILY SSF55874 5 219 3.01E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Gene3D G3DSA:3.30.565.10 18 220 6.7E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11680 605605f3032e7347428b104ab559bfec 653 Pfam PF00204 DNA gyrase B 223 395 3.7E-33 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 458 479 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 27 40 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 153 168 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 348 371 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 139 153 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 321 336 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 304 320 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 178 195 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 196 217 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11680 605605f3032e7347428b104ab559bfec 653 PRINTS PR01098 Topoisomerase IV subunit B signature 372 397 2.6E-43 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS18005 2de808825d1e7adbf0ea1b0b868e72ab 146 SUPERFAMILY SSF52080 7 145 3.01E-45 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P AFA_RS18005 2de808825d1e7adbf0ea1b0b868e72ab 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 19.587 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AFA_RS18005 2de808825d1e7adbf0ea1b0b868e72ab 146 Gene3D G3DSA:3.100.10.10 45 146 2.4E-23 T 28-03-2018 AFA_RS18005 2de808825d1e7adbf0ea1b0b868e72ab 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 5.0E-47 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18005 2de808825d1e7adbf0ea1b0b868e72ab 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 145 5.7E-30 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P AFA_RS02955 d57c75487bd3c0e204bbef3bc115571c 389 SUPERFAMILY SSF53822 23 383 4.0E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS02955 d57c75487bd3c0e204bbef3bc115571c 389 Pfam PF13458 Periplasmic binding protein 23 361 1.3E-69 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS02955 d57c75487bd3c0e204bbef3bc115571c 389 Gene3D G3DSA:3.40.50.2300 20 192 3.1E-28 T 28-03-2018 AFA_RS02955 d57c75487bd3c0e204bbef3bc115571c 389 Gene3D G3DSA:3.40.50.2300 193 349 7.5E-22 T 28-03-2018 AFA_RS11245 7bcf68d09f6bdf7a8a551b07b8aed525 165 Gene3D G3DSA:3.30.70.920 57 162 1.5E-11 T 28-03-2018 AFA_RS11245 7bcf68d09f6bdf7a8a551b07b8aed525 165 Gene3D G3DSA:1.10.10.10 1 56 9.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11245 7bcf68d09f6bdf7a8a551b07b8aed525 165 SUPERFAMILY SSF46785 24 78 8.98E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 Gene3D G3DSA:3.40.50.980 183 339 7.2E-29 T 28-03-2018 AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 Gene3D G3DSA:2.30.38.10 340 422 1.4E-17 T 28-03-2018 AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 Gene3D G3DSA:3.40.50.980 20 182 7.8E-25 T 28-03-2018 AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 Gene3D G3DSA:3.30.300.30 425 524 0.0024 T 28-03-2018 AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 SUPERFAMILY SSF56801 33 523 1.7E-77 T 28-03-2018 AFA_RS06565 dea6e9bf5221981b56c509ccea5e84ab 524 Pfam PF00501 AMP-binding enzyme 47 425 7.0E-56 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 Gene3D G3DSA:1.10.1060.10 108 237 2.9E-30 T 28-03-2018 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 230 1.4E-84 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 4.7E-10 T 28-03-2018 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 112 1.8E-33 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 SUPERFAMILY SSF46548 108 237 3.14E-39 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 SUPERFAMILY SSF54292 5 107 1.64E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS04860 88f6456e6095a2de17708d47aa29ec95 238 Gene3D G3DSA:3.10.20.30 1 107 1.2E-34 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS11560 7a6a13ceaaaa797288ddda03ff26798a 211 PIRSF PIRSF006170 1 211 8.1E-52 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 AFA_RS11560 7a6a13ceaaaa797288ddda03ff26798a 211 Gene3D G3DSA:1.25.40.10 164 209 8.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11560 7a6a13ceaaaa797288ddda03ff26798a 211 SUPERFAMILY SSF48452 97 196 7.59E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11560 7a6a13ceaaaa797288ddda03ff26798a 211 Pfam PF09976 Tetratricopeptide repeat-like domain 15 209 4.2E-55 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 AFA_RS11560 7a6a13ceaaaa797288ddda03ff26798a 211 Gene3D G3DSA:1.25.40.10 34 155 1.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11240 923368304678d486da92470c3839ae5e 161 Pfam PF13404 AsnC-type helix-turn-helix domain 15 58 6.5E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS11240 923368304678d486da92470c3839ae5e 161 SUPERFAMILY SSF46785 14 77 7.81E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11240 923368304678d486da92470c3839ae5e 161 Gene3D G3DSA:1.10.10.10 1 68 3.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11240 923368304678d486da92470c3839ae5e 161 SMART SM00344 15 123 5.7E-4 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS11240 923368304678d486da92470c3839ae5e 161 Gene3D G3DSA:3.30.70.920 69 146 5.1E-8 T 28-03-2018 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 Gene3D G3DSA:1.10.357.10 75 203 2.3E-17 T 28-03-2018 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 Gene3D G3DSA:1.10.260.40 45 74 4.8E-15 T 28-03-2018 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 SUPERFAMILY SSF46689 10 86 2.31E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS13010 352dead5a284d95331ec284612bd976d 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFA_RS13010 352dead5a284d95331ec284612bd976d 210 SUPERFAMILY SSF48498 92 198 2.35E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS13010 352dead5a284d95331ec284612bd976d 210 Gene3D G3DSA:1.10.10.60 1 44 3.1E-16 T 28-03-2018 AFA_RS11845 392fb22a6e382bd0429bfb1194b28b02 254 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 254 1.1E-76 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 AFA_RS11845 392fb22a6e382bd0429bfb1194b28b02 254 PIRSF PIRSF037834 1 254 1.9E-87 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 AFA_RS11845 392fb22a6e382bd0429bfb1194b28b02 254 SUPERFAMILY SSF47240 3 247 2.6E-68 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS11845 392fb22a6e382bd0429bfb1194b28b02 254 Gene3D G3DSA:1.20.1260.10 1 254 3.6E-59 T 28-03-2018 IPR012347 Ferritin-related AFA_RS11845 392fb22a6e382bd0429bfb1194b28b02 254 Pfam PF05138 Phenylacetic acid catabolic protein 3 254 2.6E-82 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 Gene3D G3DSA:3.40.50.2020 156 310 8.6E-46 T 28-03-2018 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 3.9E-46 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 SMART SM01400 1 117 6.7E-69 T 28-03-2018 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 Gene3D G3DSA:3.40.50.2020 1 155 5.5E-62 T 28-03-2018 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 309 47.336 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 309 2.6E-120 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 SUPERFAMILY SSF53271 65 300 6.07E-66 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFA_RS02810 0161175bdfa5290eaa08b0ef169da4a9 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 199 308 1.5E-30 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFA_RS04150 a4ad3a6705786b19e91c96a6fb54794d 441 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 30 431 2.5E-98 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS04150 a4ad3a6705786b19e91c96a6fb54794d 441 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 356 376 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS04150 a4ad3a6705786b19e91c96a6fb54794d 441 Pfam PF00860 Permease family 31 407 1.1E-86 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Gene3D G3DSA:3.40.50.10490 241 457 4.2E-61 T 28-03-2018 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 39.363 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 5.5E-251 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 SUPERFAMILY SSF53697 246 608 5.2E-109 T 28-03-2018 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Gene3D G3DSA:3.40.50.10490 458 606 1.2E-47 T 28-03-2018 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 SUPERFAMILY SSF56235 2 236 9.44E-73 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Pfam PF01380 SIS domain 292 416 1.8E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Pfam PF01380 SIS domain 462 588 4.0E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Gene3D G3DSA:3.60.20.10 2 240 5.1E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS17485 dc957704d1b4336c1f0dc66fe23354ab 608 Pfam PF13522 Glutamine amidotransferase domain 61 193 4.3E-22 T 28-03-2018 AFA_RS08825 94de644245c5485b3f92baded11e2fa5 177 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 2 140 1.0E-9 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 AFA_RS08825 94de644245c5485b3f92baded11e2fa5 177 Pfam PF13994 PgaD-like protein 1 135 5.9E-14 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 15 580 1.5E-212 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Gene3D G3DSA:3.40.50.970 7 204 4.4E-64 T 28-03-2018 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 SUPERFAMILY SSF52518 387 579 4.42E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 409 557 9.3E-51 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Gene3D G3DSA:3.40.50.970 367 564 1.7E-52 T 28-03-2018 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 210 347 4.4E-41 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 SUPERFAMILY SSF52467 207 376 8.09E-57 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS00615 ea934472627f24507c95d190e9a48435 589 SUPERFAMILY SSF52518 12 184 5.44E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Gene3D G3DSA:3.40.50.1220 205 366 8.1E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS00615 ea934472627f24507c95d190e9a48435 589 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 179 1.4E-57 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFA_RS00615 ea934472627f24507c95d190e9a48435 589 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 446 465 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFA_RS02035 2672252852ad7d3a94f46ee367f4c9ac 279 Pfam PF02219 Methylenetetrahydrofolate reductase 3 276 1.5E-82 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFA_RS02035 2672252852ad7d3a94f46ee367f4c9ac 279 Gene3D G3DSA:3.20.20.220 1 279 4.3E-90 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS02035 2672252852ad7d3a94f46ee367f4c9ac 279 SUPERFAMILY SSF51730 3 277 3.34E-92 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS02035 2672252852ad7d3a94f46ee367f4c9ac 279 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 7 276 2.9E-93 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 AFA_RS07730 003fb912c4ec95131fac2e8caaeffced 292 SUPERFAMILY SSF52335 151 288 2.98E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS07730 003fb912c4ec95131fac2e8caaeffced 292 ProSitePatterns PS01335 Methylglyoxal synthase active site. 219 227 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AFA_RS07730 003fb912c4ec95131fac2e8caaeffced 292 Gene3D G3DSA:3.40.50.1380 11 146 3.5E-12 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS07730 003fb912c4ec95131fac2e8caaeffced 292 Gene3D G3DSA:3.40.50.1380 149 290 4.2E-21 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS07730 003fb912c4ec95131fac2e8caaeffced 292 SUPERFAMILY SSF52335 13 141 7.1E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS02700 6923c7cb0042174f95e4a7eeb793f4a1 176 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 19 174 6.0E-65 T 28-03-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFA_RS02700 6923c7cb0042174f95e4a7eeb793f4a1 176 SUPERFAMILY SSF158694 12 175 6.02E-56 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFA_RS02700 6923c7cb0042174f95e4a7eeb793f4a1 176 Gene3D G3DSA:1.10.3330.10 10 176 3.7E-56 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFA_RS02700 6923c7cb0042174f95e4a7eeb793f4a1 176 Pfam PF09349 OHCU decarboxylase 17 171 3.6E-50 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 PRINTS PR00762 Chloride channel signature 388 407 5.5E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 PRINTS PR00762 Chloride channel signature 121 140 5.5E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 PRINTS PR00762 Chloride channel signature 172 191 5.5E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 PRINTS PR00762 Chloride channel signature 370 386 5.5E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 PRINTS PR00762 Chloride channel signature 335 355 5.5E-23 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 Pfam PF00654 Voltage gated chloride channel 80 420 7.7E-77 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 Gene3D G3DSA:1.10.3080.10 9 437 1.6E-80 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 SUPERFAMILY SSF81340 14 438 6.54E-95 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 Pfam PF00571 CBS domain 458 504 0.0014 T 28-03-2018 IPR000644 CBS domain AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 Pfam PF00571 CBS domain 514 570 2.5E-5 T 28-03-2018 IPR000644 CBS domain AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 SUPERFAMILY SSF54631 445 569 2.65E-17 T 28-03-2018 AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 SMART SM00116 522 572 5.8 T 28-03-2018 IPR000644 CBS domain AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 SMART SM00116 456 504 0.098 T 28-03-2018 IPR000644 CBS domain AFA_RS03585 1108a3206a43d9d00fd6f53b2fa56295 590 Gene3D G3DSA:3.10.580.10 438 580 4.9E-18 T 28-03-2018 AFA_RS16575 d29e3ed927e003b066e50783ad99ca68 354 Gene3D G3DSA:3.40.50.720 1 193 2.5E-32 T 28-03-2018 AFA_RS16575 d29e3ed927e003b066e50783ad99ca68 354 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 326 2.8E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16575 d29e3ed927e003b066e50783ad99ca68 354 Gene3D G3DSA:3.90.25.10 194 352 2.0E-49 T 28-03-2018 AFA_RS16575 d29e3ed927e003b066e50783ad99ca68 354 SUPERFAMILY SSF51735 1 337 2.5E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16575 d29e3ed927e003b066e50783ad99ca68 354 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 340 7.7E-143 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFA_RS02375 d046da5e27ae31efce6b987c68a1c1f5 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 52 120 1.1E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS02375 d046da5e27ae31efce6b987c68a1c1f5 180 Gene3D G3DSA:1.20.1290.10 44 178 2.2E-31 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS02375 d046da5e27ae31efce6b987c68a1c1f5 180 SUPERFAMILY SSF69118 1 174 2.44E-47 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS02375 d046da5e27ae31efce6b987c68a1c1f5 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 104 7.6E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS02375 d046da5e27ae31efce6b987c68a1c1f5 180 Gene3D G3DSA:1.20.5.810 11 43 1.5E-12 T 28-03-2018 AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 SUPERFAMILY SSF55186 86 202 3.66E-21 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 SUPERFAMILY SSF50447 8 77 3.11E-13 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 Pfam PF01411 tRNA synthetases class II (A) 24 71 4.0E-5 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 167 201 2.6E-6 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 Gene3D G3DSA:3.30.980.10 163 211 4.5E-6 T 28-03-2018 AFA_RS01905 0ff6635175a05b9a32b5a8fa2a4f72d2 212 Gene3D G3DSA:3.30.980.10 86 162 1.9E-5 T 28-03-2018 AFA_RS15800 d7a9ff1576c3c09bda86273d08bc6d95 125 Pfam PF01381 Helix-turn-helix 8 61 6.8E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS15800 d7a9ff1576c3c09bda86273d08bc6d95 125 SUPERFAMILY SSF47413 2 68 1.23E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS15800 d7a9ff1576c3c09bda86273d08bc6d95 125 Gene3D G3DSA:1.10.260.40 5 82 3.8E-18 T 28-03-2018 AFA_RS15800 d7a9ff1576c3c09bda86273d08bc6d95 125 SMART SM00530 7 61 9.5E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 SUPERFAMILY SSF46785 3 83 1.44E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 Pfam PF03466 LysR substrate binding domain 88 294 8.7E-38 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.2E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 Gene3D G3DSA:3.40.190.10 180 266 8.7E-20 T 28-03-2018 AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 Gene3D G3DSA:3.40.190.10 92 179 1.2E-14 T 28-03-2018 AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 SUPERFAMILY SSF53850 89 298 1.99E-38 T 28-03-2018 AFA_RS17425 a7c7a21c74f4ab0e243e4ad05a6b5436 301 Gene3D G3DSA:1.10.10.10 2 84 5.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 Pfam PF01205 Uncharacterized protein family UPF0029 17 117 1.2E-28 T 28-03-2018 IPR001498 Impact, N-terminal AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 Pfam PF09186 Domain of unknown function (DUF1949) 133 189 1.3E-11 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 SUPERFAMILY SSF54211 5 122 3.6E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 SUPERFAMILY SSF54980 128 196 8.63E-12 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 Gene3D G3DSA:3.30.70.240 128 192 3.6E-12 T 28-03-2018 AFA_RS10625 b5ee17eab6814e4e3f40443bef3ac2fa 198 Gene3D G3DSA:3.30.230.30 2 126 8.0E-40 T 28-03-2018 IPR001498 Impact, N-terminal AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 213 3.7E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Gene3D G3DSA:1.10.540.10 1 117 5.4E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 333 352 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 SUPERFAMILY SSF47203 223 377 8.86E-53 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 374 5.6E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 4.0E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 121 133 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 PIRSF PIRSF016578 209 379 6.3E-10 T 28-03-2018 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 PIRSF PIRSF016578 2 191 6.2E-9 T 28-03-2018 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Gene3D G3DSA:1.20.140.10 214 381 1.4E-52 T 28-03-2018 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 Gene3D G3DSA:2.40.110.10 118 213 8.2E-37 T 28-03-2018 AFA_RS10090 f2c5400e9eeddeb60eac0189923daacf 382 SUPERFAMILY SSF56645 2 238 4.45E-78 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 398 444 2.3E-10 T 28-03-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 SUPERFAMILY SSF52540 152 287 2.66E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 Gene3D G3DSA:3.40.50.300 136 276 8.8E-20 T 28-03-2018 AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 SMART SM00490 161 250 2.2E-16 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 Gene3D G3DSA:3.40.50.300 2 104 0.012 T 28-03-2018 AFA_RS01545 0ffc08db62a13ecd7974c41fefc48a7e 465 Pfam PF00271 Helicase conserved C-terminal domain 148 250 2.4E-11 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 PIRSF PIRSF000726 1 60 1.4E-20 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 PIRSF PIRSF000726 58 417 2.2E-132 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 Pfam PF13840 ACT domain 348 409 4.2E-14 T 28-03-2018 IPR027795 GATS-like ACT domain AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 Gene3D G3DSA:3.30.70.260 246 336 1.1E-18 T 28-03-2018 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 Gene3D G3DSA:3.30.70.260 337 412 5.1E-20 T 28-03-2018 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 413 1.9E-124 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 SUPERFAMILY SSF53633 4 250 9.29E-74 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 Gene3D G3DSA:3.40.1160.10 1 245 3.6E-74 T 28-03-2018 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 SUPERFAMILY SSF55021 261 357 3.67E-17 T 28-03-2018 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 SUPERFAMILY SSF55021 341 414 8.02E-23 T 28-03-2018 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 412 3.2E-109 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS04570 a27db925e2b2eaa3d777e85ef4da8db2 417 Pfam PF00696 Amino acid kinase family 3 229 2.6E-49 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS06430 79ac2e843f010428c7a28f9024ac9622 228 Pfam PF01914 MarC family integral membrane protein 9 213 3.0E-46 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFA_RS06430 79ac2e843f010428c7a28f9024ac9622 228 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 213 1.0E-31 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Pfam PF00501 AMP-binding enzyme 35 441 3.2E-84 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Gene3D G3DSA:3.40.50.980 25 182 6.5E-35 T 28-03-2018 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 SUPERFAMILY SSF56801 8 540 1.31E-137 T 28-03-2018 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 11 533 2.5E-218 T 28-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Gene3D G3DSA:2.30.38.10 361 436 1.1E-22 T 28-03-2018 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Gene3D G3DSA:3.40.50.980 187 359 6.1E-31 T 28-03-2018 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Gene3D G3DSA:3.30.300.30 437 547 9.9E-26 T 28-03-2018 AFA_RS01450 2b2db933cc4bf4032434b3a87fac7d84 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 523 7.3E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 146 301 4.6E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 Gene3D G3DSA:3.40.50.970 481 716 3.1E-63 T 28-03-2018 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 Gene3D G3DSA:3.40.50.970 62 480 1.1E-85 T 28-03-2018 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 Gene3D G3DSA:3.40.50.920 717 902 4.2E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 SUPERFAMILY SSF52518 63 477 1.03E-136 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 SUPERFAMILY SSF52922 714 900 1.28E-52 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 PIRSF PIRSF000156 2 902 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 SUPERFAMILY SSF52518 482 710 4.0E-94 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS10270 8771c44e161008846ebf705c7fb5a0ce 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 901 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 Pfam PF03466 LysR substrate binding domain 89 295 2.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 SUPERFAMILY SSF46785 4 112 1.16E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 Gene3D G3DSA:3.40.190.10 89 175 2.7E-15 T 28-03-2018 AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 Gene3D G3DSA:1.10.10.10 3 84 4.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 SUPERFAMILY SSF53850 89 298 4.5E-41 T 28-03-2018 AFA_RS15320 1bb93ee20877e6eb67e8bd23d3f9185c 315 Gene3D G3DSA:3.40.190.10 176 266 1.1E-24 T 28-03-2018 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Gene3D G3DSA:3.40.50.300 32 195 2.4E-28 T 28-03-2018 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 SUPERFAMILY SSF46785 271 344 3.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Gene3D G3DSA:1.10.10.10 271 341 1.8E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 24 248 6.2E-118 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 264 342 2.0E-37 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 SUPERFAMILY SSF52540 34 265 4.65E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 267 340 8.5E-34 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 356 181.541 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 SMART SM00382 65 193 3.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 Gene3D G3DSA:1.10.8.60 198 268 1.4E-31 T 28-03-2018 AFA_RS14455 0e50838485781453557baa2c8fae1f46 356 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 37 340 1.1E-146 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFA_RS02915 01a7b7ef486869834b23ada49c58917e 176 Pfam PF08534 Redoxin 34 160 5.3E-18 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFA_RS02915 01a7b7ef486869834b23ada49c58917e 176 Gene3D G3DSA:3.40.30.10 30 176 2.9E-29 T 28-03-2018 AFA_RS02915 01a7b7ef486869834b23ada49c58917e 176 SUPERFAMILY SSF52833 39 170 6.96E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS02915 01a7b7ef486869834b23ada49c58917e 176 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 25 169 4.6E-47 T 28-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 1.6E-80 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 SUPERFAMILY SSF100950 2 227 2.21E-89 T 28-03-2018 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 SMART SM00882 5 217 1.5E-94 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 Gene3D G3DSA:3.40.1080.10 1 232 6.8E-101 T 28-03-2018 AFA_RS12930 541eeae50c2cdf4917145d8ac691155c 232 Pfam PF01144 Coenzyme A transferase 7 217 6.2E-81 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS11230 658328f53dacd7a6c79e32e193c0ee19 386 Pfam PF02239 Cytochrome D1 heme domain 22 380 4.4E-105 T 28-03-2018 AFA_RS11230 658328f53dacd7a6c79e32e193c0ee19 386 SUPERFAMILY SSF51004 24 381 5.36E-70 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain AFA_RS11230 658328f53dacd7a6c79e32e193c0ee19 386 Gene3D G3DSA:2.140.10.20 15 384 1.5E-51 T 28-03-2018 AFA_RS02695 a3996fde92e0ba40481732ebf98310ae 170 Pfam PF04115 Ureidoglycolate lyase 3 162 4.4E-52 T 28-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFA_RS02695 a3996fde92e0ba40481732ebf98310ae 170 Gene3D G3DSA:2.60.120.480 3 169 2.0E-54 T 28-03-2018 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFA_RS02695 a3996fde92e0ba40481732ebf98310ae 170 SUPERFAMILY SSF51182 4 162 1.07E-54 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS02695 a3996fde92e0ba40481732ebf98310ae 170 PIRSF PIRSF017306 3 163 2.7E-45 T 28-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 SMART SM00363 147 207 5.9E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 Pfam PF00849 RNA pseudouridylate synthase 210 343 6.6E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 SUPERFAMILY SSF55174 148 236 4.19E-15 T 28-03-2018 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 214 374 4.9E-53 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 Gene3D G3DSA:3.30.70.580 206 291 2.7E-13 T 28-03-2018 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 248 262 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 Gene3D G3DSA:3.30.70.1560 292 360 4.7E-22 T 28-03-2018 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 Pfam PF01479 S4 domain 149 192 3.1E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 SUPERFAMILY SSF55120 209 374 3.84E-41 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS05085 81eee73fb3b40660b044327fc94c58be 608 Gene3D G3DSA:3.10.290.10 147 205 5.2E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 SMART SM01210 332 424 1.1E-47 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 2.4E-78 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 SUPERFAMILY SSF51246 331 424 7.14E-29 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 41.543 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 2.5E-169 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 SUPERFAMILY SSF56059 102 328 6.19E-63 T 28-03-2018 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Gene3D G3DSA:3.30.470.20 189 331 1.0E-57 T 28-03-2018 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Gene3D G3DSA:3.90.600.10 332 425 9.3E-32 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 4.3E-28 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Gene3D G3DSA:3.40.50.20 2 84 2.3E-37 T 28-03-2018 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 SMART SM01209 101 298 1.5E-135 T 28-03-2018 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.7E-36 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 SUPERFAMILY SSF52440 1 101 4.17E-35 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS12705 af937fef9646ddcdf5d30c821495b3d4 429 Gene3D G3DSA:3.30.1490.20 85 187 1.3E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 495 1.1E-203 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 PIRSF PIRSF000538 1 497 7.2E-166 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 SUPERFAMILY SSF53067 3 252 2.59E-89 T 28-03-2018 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 Gene3D G3DSA:3.30.420.40 246 497 1.7E-72 T 28-03-2018 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 Gene3D G3DSA:3.30.420.40 1 245 1.9E-85 T 28-03-2018 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 SUPERFAMILY SSF53067 252 494 2.33E-76 T 28-03-2018 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 Hamap MF_00186 Glycerol kinase [glpK]. 1 497 52.801 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 249 2.4E-74 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 450 5.5E-56 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFA_RS05710 d5a0bbc17066885af75e36758fe9906e 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFA_RS08070 64299636422666796dbb67affaf2895c 290 SUPERFAMILY SSF53850 85 290 1.07E-37 T 28-03-2018 AFA_RS08070 64299636422666796dbb67affaf2895c 290 Gene3D G3DSA:3.40.190.10 169 259 5.4E-14 T 28-03-2018 AFA_RS08070 64299636422666796dbb67affaf2895c 290 Gene3D G3DSA:3.40.190.10 79 168 7.8E-18 T 28-03-2018 AFA_RS08070 64299636422666796dbb67affaf2895c 290 SUPERFAMILY SSF46785 1 109 2.34E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08070 64299636422666796dbb67affaf2895c 290 Pfam PF03466 LysR substrate binding domain 86 289 3.6E-42 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08070 64299636422666796dbb67affaf2895c 290 Gene3D G3DSA:1.10.10.10 1 78 7.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08070 64299636422666796dbb67affaf2895c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08070 64299636422666796dbb67affaf2895c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08070 64299636422666796dbb67affaf2895c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08070 64299636422666796dbb67affaf2895c 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.5E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 Gene3D G3DSA:2.30.40.10 382 462 0.021 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 Gene3D G3DSA:3.20.20.140 68 381 4.7E-40 T 28-03-2018 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 SUPERFAMILY SSF51556 62 391 1.02E-62 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 SUPERFAMILY SSF51338 375 465 1.15E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 Gene3D G3DSA:2.30.40.10 7 67 0.088 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 Pfam PF01979 Amidohydrolase family 60 445 1.8E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS17655 87a35dd54672892773c362ce2eb6dc48 473 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 9 470 8.7E-161 T 28-03-2018 IPR010252 Formiminoglutamate deiminase AFA_RS08155 316b863f9e18874c976019022b70b345 413 Pfam PF07690 Major Facilitator Superfamily 26 365 1.9E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS08155 316b863f9e18874c976019022b70b345 413 Gene3D G3DSA:1.20.1250.20 2 195 8.7E-11 T 28-03-2018 AFA_RS08155 316b863f9e18874c976019022b70b345 413 Gene3D G3DSA:1.20.1250.20 224 407 4.9E-12 T 28-03-2018 AFA_RS08155 316b863f9e18874c976019022b70b345 413 SUPERFAMILY SSF103473 4 399 7.19E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS07780 43ead8daccde0224c26cb00f7f38f162 569 Pfam PF02272 DHHA1 domain 324 452 1.0E-26 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFA_RS07780 43ead8daccde0224c26cb00f7f38f162 569 SUPERFAMILY SSF64182 50 461 6.28E-115 T 28-03-2018 AFA_RS07780 43ead8daccde0224c26cb00f7f38f162 569 Pfam PF01368 DHH family 77 211 1.2E-8 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFA_RS07780 43ead8daccde0224c26cb00f7f38f162 569 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 563 1.6E-146 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 AFA_RS07780 43ead8daccde0224c26cb00f7f38f162 569 Gene3D G3DSA:3.90.1640.10 54 252 3.7E-24 T 28-03-2018 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 SUPERFAMILY SSF142984 270 353 5.1E-26 T 28-03-2018 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 371 382 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 SUPERFAMILY SSF140490 355 452 3.01E-39 T 28-03-2018 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 SUPERFAMILY SSF142019 42 269 3.4E-82 T 28-03-2018 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 SMART SM00928 358 403 1.0E-26 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 Gene3D G3DSA:3.10.560.10 267 316 1.4E-4 T 28-03-2018 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 362 443 1.4E-31 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 44 444 1.1E-190 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 77 248 1.7E-44 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13395 2b7e7d11943db98e4e4f70f7c7a6687a 455 Pfam PF10531 SLBB domain 272 320 9.0E-14 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 SUPERFAMILY SSF46946 2 114 8.01E-43 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.1E-50 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Pfam PF00416 Ribosomal protein S13/S18 63 108 2.6E-16 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Pfam PF00416 Ribosomal protein S13/S18 3 60 8.1E-14 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.983 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Gene3D G3DSA:1.10.8.50 1 66 2.0E-21 T 28-03-2018 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 PIRSF PIRSF002134 1 121 5.3E-40 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Gene3D G3DSA:4.10.910.10 67 85 9.4E-16 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17985 2cf5e0ae43873798e1249356e7fade45 121 Gene3D G3DSA:4.10.910.10 86 121 9.5E-24 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 279 298 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 213 234 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 257 278 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 235 256 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 11 31 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 193 211 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 PRINTS PR01002 Flagellar protein FlgJ signature 299 317 2.0E-38 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 181 315 5.9E-21 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 Pfam PF10135 Rod binding protein 57 103 7.9E-8 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 SMART SM00047 166 321 6.9E-42 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 Gene3D G3DSA:1.10.530.10 164 318 1.5E-37 T 28-03-2018 AFA_RS05860 53003f3075d23b4ad27b5ba620d64f50 321 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 17 314 1.6E-99 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 AFA_RS05670 3d45c6f3723b640eaadc5d2983f65887 142 Pfam PF04143 Sulphur transport 9 132 1.4E-7 T 28-03-2018 IPR007272 Sulphur transport domain AFA_RS02470 2af582dc4810d13218b4862c1e87b5f0 345 Pfam PF01904 Protein of unknown function DUF72 70 338 6.8E-39 T 28-03-2018 IPR002763 Protein of unknown function DUF72 AFA_RS02470 2af582dc4810d13218b4862c1e87b5f0 345 SUPERFAMILY SSF117396 49 340 1.11E-45 T 28-03-2018 IPR002763 Protein of unknown function DUF72 AFA_RS02470 2af582dc4810d13218b4862c1e87b5f0 345 Gene3D G3DSA:3.20.20.410 36 344 2.6E-57 T 28-03-2018 IPR002763 Protein of unknown function DUF72 AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 7.4E-47 T 28-03-2018 AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 Gene3D G3DSA:3.40.50.720 9 255 5.0E-56 T 28-03-2018 AFA_RS08570 73480fcb8f8370a2e2f6c3f4dd8a8b01 256 SUPERFAMILY SSF51735 9 253 2.77E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS08325 26d77d65c104854ac405aca785d89424 543 Gene3D G3DSA:2.120.10.70 131 377 4.3E-21 T 28-03-2018 AFA_RS08325 26d77d65c104854ac405aca785d89424 543 SUPERFAMILY SSF102588 66 141 6.8E-7 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 AFA_RS08325 26d77d65c104854ac405aca785d89424 543 Gene3D G3DSA:2.120.10.70 378 534 3.0E-9 T 28-03-2018 AFA_RS08325 26d77d65c104854ac405aca785d89424 543 SUPERFAMILY SSF89372 194 433 7.98E-16 T 28-03-2018 AFA_RS05720 11f78e95132a02c1e2b0cf52e77157cc 165 SUPERFAMILY SSF54001 40 164 1.67E-38 T 28-03-2018 AFA_RS05720 11f78e95132a02c1e2b0cf52e77157cc 165 Gene3D G3DSA:2.30.260.10 90 164 2.3E-22 T 28-03-2018 AFA_RS05720 11f78e95132a02c1e2b0cf52e77157cc 165 Pfam PF00877 NlpC/P60 family 56 160 1.1E-27 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFA_RS05720 11f78e95132a02c1e2b0cf52e77157cc 165 Gene3D G3DSA:3.90.1720.10 27 89 1.4E-13 T 28-03-2018 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 SUPERFAMILY SSF55681 2 251 9.69E-110 T 28-03-2018 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 651 693 1.0E-16 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Pfam PF02272 DHHA1 domain 731 869 2.1E-25 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 1.4E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 1.4E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 1.4E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 1.4E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 1.4E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 852 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Pfam PF01411 tRNA synthetases class II (A) 5 554 6.7E-225 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 SUPERFAMILY SSF50447 451 550 8.48E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 SMART SM00863 651 693 2.4E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 873 200.419 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 SUPERFAMILY SSF101353 252 441 1.27E-60 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Gene3D G3DSA:3.30.980.10 551 710 6.0E-42 T 28-03-2018 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 Gene3D G3DSA:3.30.930.10 1 248 5.9E-118 T 28-03-2018 AFA_RS11620 9f5e411f1b6283f97000a39803720557 875 SUPERFAMILY SSF55186 550 709 1.7E-49 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 SUPERFAMILY SSF52402 1 148 1.67E-36 T 28-03-2018 AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 PRINTS PR01438 Universal stress protein signature 108 120 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 PRINTS PR01438 Universal stress protein signature 126 148 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 PRINTS PR01438 Universal stress protein signature 2 20 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 Gene3D G3DSA:3.40.50.620 1 153 1.3E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 Pfam PF00582 Universal stress protein family 1 148 4.1E-31 T 28-03-2018 IPR006016 UspA GO:0006950 AFA_RS03025 a658dc471b9e045f0eebf1a94be21706 153 PIRSF PIRSF006276 1 151 1.8E-18 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Pfam PF00501 AMP-binding enzyme 467 851 8.5E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Pfam PF00668 Condensation domain 12 427 3.6E-56 T 28-03-2018 IPR001242 Condensation domain AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 875 1.9E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Pfam PF13193 AMP-binding enzyme C-terminal domain 859 934 3.2E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SUPERFAMILY SSF56801 430 970 6.41E-153 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SUPERFAMILY SSF52777 193 430 1.11E-35 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:3.40.50.1820 1040 1294 8.3E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:3.40.50.980 602 753 4.5E-41 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Pfam PF00975 Thioesterase domain 1052 1187 5.6E-23 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SUPERFAMILY SSF53474 1030 1291 8.82E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SUPERFAMILY SSF47336 956 1026 6.67E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:1.10.1200.10 965 1032 1.6E-16 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:3.30.559.10 3 196 7.3E-20 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Pfam PF00550 Phosphopantetheine attachment site 961 1025 1.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:2.30.38.10 754 843 1.1E-25 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:3.40.50.980 455 601 8.2E-37 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SUPERFAMILY SSF52777 13 178 1.22E-30 T 28-03-2018 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 SMART SM00823 Phosphopantetheine attachment site 959 1029 0.0027 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 ProSitePatterns PS00455 Putative AMP-binding domain signature. 596 607 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS01440 ae6e9470e8ea941958f4c7642e2d3f20 1307 Gene3D G3DSA:3.30.300.30 846 964 3.6E-35 T 28-03-2018 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 Gene3D G3DSA:3.40.190.10 92 172 5.5E-19 T 28-03-2018 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 SUPERFAMILY SSF46785 6 108 5.99E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 Gene3D G3DSA:3.40.190.10 173 257 1.4E-17 T 28-03-2018 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 SUPERFAMILY SSF53850 90 287 8.11E-36 T 28-03-2018 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 Pfam PF03466 LysR substrate binding domain 89 287 3.8E-37 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS11350 24e9401297ea1b64c6543597b937d6eb 291 Gene3D G3DSA:1.10.10.10 1 91 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SMART SM00316 136 202 1.0E-10 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF47794 430 491 1.07E-12 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:1.10.150.20 427 494 5.0E-17 T 28-03-2018 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:1.10.150.20 356 423 7.0E-11 T 28-03-2018 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:2.40.50.140 139 200 5.6E-14 T 28-03-2018 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:3.30.1480.10 1 132 1.2E-43 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF50249 136 201 5.85E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF54814 202 279 4.58E-28 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:3.30.300.20 201 278 1.8E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF54814 281 344 4.9E-14 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Pfam PF14520 Helix-hairpin-helix domain 432 486 1.3E-7 T 28-03-2018 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 6.3E-18 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Gene3D G3DSA:3.30.300.20 280 350 3.5E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Pfam PF00575 S1 RNA binding domain 139 193 2.6E-8 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF69705 1 129 2.09E-39 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 4.2E-122 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.94 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 SUPERFAMILY SSF47794 358 417 1.55E-15 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Pfam PF08529 NusA N-terminal domain 4 127 2.1E-37 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFA_RS05095 1b297a86680ae2ab74ab591bb275a80b 494 Pfam PF13184 NusA-like KH domain 232 299 1.2E-24 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 SMART SM00729 96 304 2.0E-14 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 TIGRFAM TIGR00510 lipA: lipoyl synthase 44 326 6.8E-129 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 PIRSF PIRSF005963 2 333 6.5E-127 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 Hamap MF_00206 Lipoyl synthase [lipA]. 48 334 151.885 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 Pfam PF04055 Radical SAM superfamily 103 263 4.5E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 27 85 2.4E-6 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 Gene3D G3DSA:3.20.20.70 25 332 5.7E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01250 65452a6d12623706a79fedfb83b51e4a 334 SUPERFAMILY SSF102114 64 329 1.31E-66 T 28-03-2018 AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 Gene3D G3DSA:1.10.150.20 15 55 2.0E-6 T 28-03-2018 AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 SUPERFAMILY SSF47781 43 97 1.65E-18 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 Pfam PF12836 Helix-hairpin-helix motif 45 96 3.0E-15 T 28-03-2018 AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 SMART SM00278 52 71 0.0072 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 SMART SM00278 83 102 770.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS11930 c35881ae5f6efcdee311cefbe543efbe 128 Gene3D G3DSA:1.10.150.280 56 106 2.1E-17 T 28-03-2018 AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 SUPERFAMILY SSF56235 17 491 3.47E-119 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 Pfam PF01019 Gamma-glutamyltranspeptidase 36 305 2.3E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 8.8E-31 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 8.8E-31 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 363 378 8.8E-31 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS17820 adc5c14e9333b603d62cebf2785b6d0b 493 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 8.8E-31 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 Pfam PF00593 TonB dependent receptor 276 705 6.6E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 689 706 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 Gene3D G3DSA:2.170.130.10 23 179 2.6E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 68 706 1.6E-102 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 169 6.7E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 SUPERFAMILY SSF56935 28 706 3.66E-121 T 28-03-2018 AFA_RS16890 4a430ed36a81df65bebe869dfc8ca1f5 706 Gene3D G3DSA:2.40.170.20 180 706 4.2E-85 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Gene3D G3DSA:3.30.365.10 326 420 2.2E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 SUPERFAMILY SSF56003 45 232 4.71E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 SMART SM01008 206 292 3.1E-9 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Gene3D G3DSA:3.30.365.10 35 191 1.2E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Gene3D G3DSA:3.30.365.10 421 566 1.3E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 607 690 6.6E-12 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 331 556 1.3E-15 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 46 169 1.9E-22 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 SUPERFAMILY SSF54665 207 293 5.23E-6 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 SUPERFAMILY SSF56003 324 745 1.74E-96 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Gene3D G3DSA:3.30.365.10 567 752 1.3E-41 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 PIRSF PIRSF036389 5 744 2.0E-184 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related AFA_RS14965 9bac3e986c0ef30a3ba60b99874407e0 752 Gene3D G3DSA:3.90.1170.50 192 303 1.9E-20 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS01500 e1dbff1ccb69066cdb59f63ad860001e 254 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01500 e1dbff1ccb69066cdb59f63ad860001e 254 SUPERFAMILY SSF52540 1 226 8.61E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01500 e1dbff1ccb69066cdb59f63ad860001e 254 Gene3D G3DSA:3.40.50.300 1 221 2.1E-59 T 28-03-2018 AFA_RS01500 e1dbff1ccb69066cdb59f63ad860001e 254 SMART SM00382 31 224 7.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01500 e1dbff1ccb69066cdb59f63ad860001e 254 Pfam PF00005 ABC transporter 22 161 3.7E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 SUPERFAMILY SSF50129 318 368 1.41E-12 T 28-03-2018 IPR011032 GroES-like AFA_RS17600 69d1598f1b445374d429002c811cc203 368 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 368 8.9E-191 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 SUPERFAMILY SSF51735 160 333 1.36E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17600 69d1598f1b445374d429002c811cc203 368 SMART SM00829 12 366 4.5E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 151 2.6E-23 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 Gene3D G3DSA:3.40.50.10730 183 310 2.6E-32 T 28-03-2018 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 SUPERFAMILY SSF50129 1 185 2.59E-71 T 28-03-2018 IPR011032 GroES-like AFA_RS17600 69d1598f1b445374d429002c811cc203 368 Pfam PF00107 Zinc-binding dehydrogenase 197 320 3.9E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS17600 69d1598f1b445374d429002c811cc203 368 Gene3D G3DSA:3.90.180.10 3 182 2.6E-49 T 28-03-2018 AFA_RS08610 18e0d1299809945a31b28b2305cb7ce4 445 Pfam PF00860 Permease family 18 397 8.4E-72 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS08610 18e0d1299809945a31b28b2305cb7ce4 445 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 345 365 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 Gene3D G3DSA:2.40.30.10 2 96 1.2E-16 T 28-03-2018 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 SUPERFAMILY SSF63380 6 99 2.15E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 Gene3D G3DSA:3.40.50.80 97 258 4.6E-21 T 28-03-2018 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 SUPERFAMILY SSF52343 103 256 1.57E-39 T 28-03-2018 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 51 58 6.2E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 6.2E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 6.2E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 98 5.8E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 1.6E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 1.6E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 1.6E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 1.6E-6 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS09340 d99e866eecd5e16a64e19003b79685ca 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 228 1.9E-7 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2778 2900 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1714 1836 3.14E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 5579 5659 1.1E-11 T 28-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3310 3430 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3842 3962 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2379 2499 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3177 3297 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1049 1169 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3975 4095 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 5534 5552 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1847 1967 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 783 903 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF51120 5439 5463 1.26E-19 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF51120 5492 5608 1.26E-19 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 4108 4228 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00327 5202 5400 5.3E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3437 3543 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2506 2612 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1575 1681 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 644 750 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4368 4474 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1974 2080 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1043 1149 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3969 4075 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1176 1282 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 511 617 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4501 4607 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1442 1548 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2905 3011 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3038 3144 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2107 2213 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4634 4740 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1309 1415 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3836 3942 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 445 478 0.25 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3703 3809 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2240 2346 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1841 1947 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4102 4208 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3171 3277 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2772 2878 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2373 2479 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3570 3676 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 2639 2745 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 777 883 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 3304 3410 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 1708 1814 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4235 4341 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 4766 4856 24.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF03160 Calx-beta domain 910 1016 42.0 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3443 3563 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 4241 4361 3.79E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1581 1701 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2421 2431 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 559 569 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1756 1766 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4283 4293 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1091 1101 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3086 3096 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2953 2963 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1224 1234 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 692 702 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3219 3229 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4150 4160 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4416 4426 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3485 3495 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3751 3761 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3618 3628 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4017 4027 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3884 3894 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 3352 3362 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1490 1500 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2687 2697 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 825 835 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4682 4692 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 4549 4559 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 958 968 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2820 2830 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1357 1367 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2288 2298 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1623 1633 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2554 2564 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2022 2032 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 1889 1899 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SMART SM00203 2155 2165 5700.0 T 28-03-2018 IPR008215 Tachykinin domain GO:0007217 Reactome: R-HSA-380095|Reactome: R-HSA-416476 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1182 1304 3.14E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 4507 4627 3.79E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 4374 4494 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 371 504 1.44E-7 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1315 1435 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 5543 5561 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Pfam PF13519 von Willebrand factor type A domain 5206 5325 7.1E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3576 3696 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 916 1036 3.92E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 4767 4884 3.31E-7 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2113 2233 3.79E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1448 1568 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 650 772 3.14E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 1980 2100 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3709 3829 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 517 637 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2911 3031 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 Gene3D G3DSA:3.40.50.410 5191 5433 1.3E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2246 2366 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF53300 5193 5335 1.63E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 PRINTS PR00313 NodO calcium binding signature 5547 5555 3.3E-8 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 PRINTS PR00313 NodO calcium binding signature 5556 5565 3.3E-8 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 PRINTS PR00313 NodO calcium binding signature 5442 5453 3.3E-8 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 PRINTS PR00313 NodO calcium binding signature 5529 5537 3.3E-8 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 3044 3164 3.27E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2645 2765 3.4E-5 T 28-03-2018 AFA_RS18065 26fefe2b7c80800e6acc26d7d1e6f462 5667 SUPERFAMILY SSF141072 2512 2634 3.4E-5 T 28-03-2018 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 SUPERFAMILY SSF46689 10 86 4.24E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 SUPERFAMILY SSF48498 91 168 4.04E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.7E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 Gene3D G3DSA:1.10.10.60 1 60 4.6E-19 T 28-03-2018 AFA_RS07985 32cc3ff9393e07242fec4646039f9595 215 Gene3D G3DSA:1.10.357.10 61 211 1.2E-15 T 28-03-2018 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 Pfam PF02803 Thiolase, C-terminal domain 274 396 1.7E-42 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 395 2.1E-140 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 PIRSF PIRSF000429 1 397 3.6E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 SUPERFAMILY SSF53901 275 396 3.34E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 Pfam PF00108 Thiolase, N-terminal domain 7 266 1.2E-76 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 ProSitePatterns PS00099 Thiolases active site. 378 391 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 SUPERFAMILY SSF53901 3 272 5.32E-76 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 Gene3D G3DSA:3.40.47.10 279 394 1.1E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 Gene3D G3DSA:3.40.47.10 146 278 3.5E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS17070 6c561bf9bec26ba2320f45e4d04c7ddd 397 Gene3D G3DSA:3.40.47.10 1 136 5.7E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SMART SM00388 456 526 7.0E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SUPERFAMILY SSF55785 306 432 8.2E-22 T 28-03-2018 IPR000014 PAS domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Gene3D G3DSA:3.30.450.20 72 215 0.011 T 28-03-2018 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Pfam PF00989 PAS fold 320 431 7.4E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 316 439 4.3E-23 T 28-03-2018 IPR000014 PAS domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Pfam PF00512 His Kinase A (phospho-acceptor) domain 457 523 2.0E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SMART SM00091 318 386 2.0E-6 T 28-03-2018 IPR000014 PAS domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Gene3D G3DSA:3.30.450.20 291 447 1.4E-24 T 28-03-2018 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SUPERFAMILY SSF47384 453 525 8.83E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 662 675 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 623 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 627 637 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 656 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SMART SM00387 568 678 1.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SMART SM00086 392 434 3.7E-5 T 28-03-2018 IPR001610 PAC motif AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Gene3D G3DSA:3.30.565.10 526 680 1.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 568 676 2.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 Gene3D G3DSA:1.10.287.130 448 522 6.4E-7 T 28-03-2018 AFA_RS03100 0c75f3cabf136adcc839239c6968f2e1 680 SUPERFAMILY SSF55874 518 676 1.26E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06700 6d2ce6c820a64f192adb4f4aa24638d4 303 Pfam PF04381 Putative exonuclease, RdgC 1 296 4.3E-112 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 AFA_RS06700 6d2ce6c820a64f192adb4f4aa24638d4 303 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 35.135 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 SUPERFAMILY SSF53720 32 432 2.35E-89 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 8 431 41.775 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 8.5E-83 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 Gene3D G3DSA:3.40.50.1980 230 375 1.1E-68 T 28-03-2018 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 Gene3D G3DSA:3.40.50.1980 29 229 9.5E-88 T 28-03-2018 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 37 430 2.8E-163 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 PIRSF PIRSF000099 1 434 1.3E-163 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS17140 e8b7bf2a3496a65a40d68533c505394b 434 Pfam PF00815 Histidinol dehydrogenase 26 431 1.6E-169 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 SMART SM00421 147 204 2.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 Gene3D G3DSA:1.10.10.10 118 214 2.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 5.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 SMART SM00448 2 116 7.5E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 SUPERFAMILY SSF46894 141 209 2.24E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 SUPERFAMILY SSF52172 3 128 1.99E-22 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 Pfam PF00072 Response regulator receiver domain 5 113 2.6E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12420 71078d672e5a162c723c5777bd77b52e 220 Gene3D G3DSA:3.40.50.2300 3 117 2.7E-21 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 308 329 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 Gene3D G3DSA:3.10.50.40 258 395 7.1E-38 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 Gene3D G3DSA:3.10.50.40 396 523 0.01 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 Pfam PF13624 SurA N-terminal domain 1 162 7.6E-40 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 Gene3D G3DSA:1.10.4030.10 37 167 3.2E-14 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 Pfam PF00639 PPIC-type PPIASE domain 273 367 8.5E-26 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 SUPERFAMILY SSF54534 259 367 3.6E-29 T 28-03-2018 AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 SUPERFAMILY SSF109998 200 238 1.41E-24 T 28-03-2018 IPR027304 Trigger factor/SurA domain AFA_RS10505 2c5783cad6397190c5c8e0cf46182a21 652 SUPERFAMILY SSF109998 39 166 1.41E-24 T 28-03-2018 IPR027304 Trigger factor/SurA domain AFA_RS12100 fbfa27b090ab9339e9787e7a0aa3472f 217 SUPERFAMILY SSF50475 12 186 1.0E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS12100 fbfa27b090ab9339e9787e7a0aa3472f 217 Pfam PF04299 Putative FMN-binding domain 1 167 1.8E-61 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type AFA_RS12100 fbfa27b090ab9339e9787e7a0aa3472f 217 Gene3D G3DSA:2.30.110.10 1 211 2.5E-57 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS12100 fbfa27b090ab9339e9787e7a0aa3472f 217 PIRSF PIRSF010372 1 212 1.8E-75 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 SUPERFAMILY SSF75217 1 236 1.44E-94 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 Gene3D G3DSA:1.10.1270.20 175 250 1.2E-27 T 28-03-2018 AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 PIRSF PIRSF000386 1 249 1.0E-93 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 224 7.1E-60 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 253 107.979 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 1.4E-88 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFA_RS11600 afea5832a023e9234f54a3cab968212a 253 Gene3D G3DSA:3.40.1280.10 1 171 1.6E-70 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS17020 746ceabc0310c6f3dd2558cb4903f03e 220 SUPERFAMILY SSF52540 2 213 7.44E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17020 746ceabc0310c6f3dd2558cb4903f03e 220 Pfam PF00005 ABC transporter 22 153 5.6E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS17020 746ceabc0310c6f3dd2558cb4903f03e 220 Gene3D G3DSA:3.40.50.300 1 218 8.7E-37 T 28-03-2018 AFA_RS17020 746ceabc0310c6f3dd2558cb4903f03e 220 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS17020 746ceabc0310c6f3dd2558cb4903f03e 220 SMART SM00382 31 208 6.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 Pfam PF01614 Bacterial transcriptional regulator 136 257 4.7E-19 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 Gene3D G3DSA:3.30.450.40 88 265 3.0E-33 T 28-03-2018 IPR029016 GAF domain-like AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 Gene3D G3DSA:1.10.10.10 7 87 2.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 SMART SM00346 13 104 1.9E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 SUPERFAMILY SSF55781 92 261 1.77E-31 T 28-03-2018 IPR029016 GAF domain-like AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 SUPERFAMILY SSF46785 15 86 1.34E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10365 2599985ded8cbaf37c01ee323f3c0c03 268 Pfam PF09339 IclR helix-turn-helix domain 15 62 1.6E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 ProSitePatterns PS00056 Ribosomal protein S17 signature. 62 74 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 SUPERFAMILY SSF50249 10 89 4.71E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 Gene3D G3DSA:2.40.50.140 11 88 1.1E-30 T 28-03-2018 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 11 86 25.016 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 PRINTS PR00973 Ribosomal protein S17 family signature 30 53 7.8E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 PRINTS PR00973 Ribosomal protein S17 family signature 62 72 7.8E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 PRINTS PR00973 Ribosomal protein S17 family signature 72 79 7.8E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 Pfam PF00366 Ribosomal protein S17 16 82 4.6E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 11 82 6.0E-31 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18225 6865c5a6d3d68f1430cf11259a17050d 91 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 12 82 3.6E-36 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 482 36.974 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 2.0E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 2.0E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 2.0E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 2.0E-27 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 SUPERFAMILY SSF47323 333 481 3.14E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 SMART SM00840 359 414 2.9E-21 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 SUPERFAMILY SSF52374 2 329 2.63E-80 T 28-03-2018 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 482 3.5E-154 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 Gene3D G3DSA:1.20.120.640 323 406 1.6E-18 T 28-03-2018 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 Pfam PF09190 DALR domain 359 411 3.0E-17 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 Gene3D G3DSA:3.40.50.620 1 322 7.3E-76 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS04550 b28a8e34692e63e7e3a5319ae8d37878 483 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 330 1.2E-112 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFA_RS16145 f548faf90605a570219f537653ddd973 332 Gene3D G3DSA:3.40.50.1980 78 198 2.6E-20 T 28-03-2018 AFA_RS16145 f548faf90605a570219f537653ddd973 332 Pfam PF01497 Periplasmic binding protein 82 275 1.9E-15 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 AFA_RS16145 f548faf90605a570219f537653ddd973 332 Gene3D G3DSA:3.40.50.1980 199 328 8.2E-14 T 28-03-2018 AFA_RS16145 f548faf90605a570219f537653ddd973 332 SUPERFAMILY SSF53807 80 324 2.94E-39 T 28-03-2018 AFA_RS05895 0233b3d6a19ecbe27ccd0de1aff2d1e5 229 Gene3D G3DSA:3.30.420.10 27 216 1.7E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS05895 0233b3d6a19ecbe27ccd0de1aff2d1e5 229 Pfam PF00929 Exonuclease 38 195 4.5E-15 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS05895 0233b3d6a19ecbe27ccd0de1aff2d1e5 229 SMART SM00479 35 205 1.3E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS05895 0233b3d6a19ecbe27ccd0de1aff2d1e5 229 SUPERFAMILY SSF53098 29 208 5.91E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS05895 0233b3d6a19ecbe27ccd0de1aff2d1e5 229 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 31 219 2.6E-22 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS06595 491cc6e3f7d5c6720447f4b9e9cf43a2 370 SUPERFAMILY SSF53383 19 369 5.59E-50 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS06595 491cc6e3f7d5c6720447f4b9e9cf43a2 370 Pfam PF00266 Aminotransferase class-V 54 336 3.4E-18 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS06595 491cc6e3f7d5c6720447f4b9e9cf43a2 370 Gene3D G3DSA:3.40.640.10 18 280 2.5E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS06595 491cc6e3f7d5c6720447f4b9e9cf43a2 370 Gene3D G3DSA:3.90.1150.10 281 370 2.1E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 SMART SM00965 84 135 1.6E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 Pfam PF07715 TonB-dependent Receptor Plug Domain 160 275 2.9E-7 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 Gene3D G3DSA:2.40.170.20 277 905 1.6E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 Gene3D G3DSA:2.170.130.10 156 276 4.9E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 SUPERFAMILY SSF56935 141 296 2.15E-53 T 28-03-2018 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 SUPERFAMILY SSF56935 658 905 2.15E-53 T 28-03-2018 AFA_RS06145 a8bca6186217a44240c7b08f47725580 905 SUPERFAMILY SSF56935 323 630 2.15E-53 T 28-03-2018 AFA_RS14635 833855b35621072dc354bc71f7523255 167 SUPERFAMILY SSF103088 57 164 4.84E-31 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14635 833855b35621072dc354bc71f7523255 167 Gene3D G3DSA:3.30.1330.60 40 167 4.7E-30 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14635 833855b35621072dc354bc71f7523255 167 Pfam PF00691 OmpA family 64 159 6.8E-19 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14635 833855b35621072dc354bc71f7523255 167 PRINTS PR01021 OMPA domain signature 65 87 1.1E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS14635 833855b35621072dc354bc71f7523255 167 PRINTS PR01021 OMPA domain signature 95 110 1.1E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS14635 833855b35621072dc354bc71f7523255 167 PRINTS PR01021 OMPA domain signature 110 126 1.1E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS14635 833855b35621072dc354bc71f7523255 167 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 62 165 9.6E-40 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 Gene3D G3DSA:3.20.20.450 263 507 7.9E-27 T 28-03-2018 IPR001633 EAL domain AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 Gene3D G3DSA:1.10.10.10 121 235 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 SUPERFAMILY SSF46894 147 231 1.19E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 SMART SM00052 257 511 1.7E-4 T 28-03-2018 IPR001633 EAL domain AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 SUPERFAMILY SSF141868 280 516 1.06E-23 T 28-03-2018 IPR001633 EAL domain AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 SMART SM00862 157 230 1.1E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 Pfam PF00563 EAL domain 280 504 1.1E-21 T 28-03-2018 IPR001633 EAL domain AFA_RS01400 0723107ffd9e1d92b4264647f371f158 538 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 230 1.6E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 Gene3D G3DSA:3.90.940.10 1 65 2.3E-19 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 SUPERFAMILY SSF63562 1 62 1.06E-19 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 Pfam PF01192 RNA polymerase Rpb6 8 55 2.4E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 55 1.6E-16 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 SMART SM01409 8 59 1.1E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AFA_RS10480 d730357f58693663464d8898fe9c96ba 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 16.525 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 233 39.594 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 107 114 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 SUPERFAMILY SSF53448 6 233 6.53E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 231 3.6E-61 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 Gene3D G3DSA:3.90.550.10 1 233 1.4E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS13325 ab2cf2c9c7be7012255f8c033ee62f05 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 231 1.9E-60 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 39 278 3.2E-71 T 28-03-2018 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 Gene3D G3DSA:3.40.190.10 132 274 6.3E-34 T 28-03-2018 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 Gene3D G3DSA:3.40.190.10 32 131 8.5E-8 T 28-03-2018 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 11 255 1.2E-76 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 SMART SM00062 36 265 0.001 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 11 288 6.0E-83 T 28-03-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 AFA_RS15365 ba5d8dba1c48147bffd3281e00cab506 296 SUPERFAMILY SSF53850 58 247 2.72E-49 T 28-03-2018 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 303 1.1E-15 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 Gene3D G3DSA:3.30.70.250 139 177 7.1E-12 T 28-03-2018 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 Gene3D G3DSA:3.40.366.10 2 138 5.5E-17 T 28-03-2018 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 Pfam PF00698 Acyl transferase domain 54 278 3.1E-17 T 28-03-2018 IPR014043 Acyl transferase AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 SUPERFAMILY SSF55048 129 192 3.79E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 SUPERFAMILY SSF52151 193 294 1.7E-39 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 SUPERFAMILY SSF52151 2 128 1.7E-39 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS04465 00a1612f6b07c8499b497868a2d48dd8 309 Gene3D G3DSA:3.40.366.10 178 306 1.5E-17 T 28-03-2018 AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 SMART SM00729 25 244 3.8E-45 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 Gene3D G3DSA:3.20.20.70 20 328 1.2E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 Pfam PF04055 Radical SAM superfamily 30 191 6.2E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 Pfam PF06969 HemN C-terminal domain 327 388 3.3E-12 T 28-03-2018 IPR010723 HemN, C-terminal AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 27 372 1.0E-104 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFA_RS09295 6700823edd2636186e1c50e720e1307b 404 SUPERFAMILY SSF102114 18 399 1.06E-102 T 28-03-2018 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 Gene3D G3DSA:2.30.330.10 72 166 2.7E-32 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 85 155 9.3E-27 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 118 5.5E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 PRINTS PR00956 Flagellar motor switch protein FliN signature 85 101 5.5E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 PRINTS PR00956 Flagellar motor switch protein FliN signature 118 131 5.5E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 PRINTS PR00956 Flagellar motor switch protein FliN signature 131 146 5.5E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 82 157 1.0E-34 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05920 3ff1429b093852987ee532fd4f6302cd 168 SUPERFAMILY SSF101801 83 164 5.62E-27 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 SMART SM00487 150 351 1.2E-11 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 Gene3D G3DSA:3.40.50.300 346 592 9.8E-20 T 28-03-2018 AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 Gene3D G3DSA:3.40.50.300 135 343 4.7E-23 T 28-03-2018 AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 Pfam PF00270 DEAD/DEAH box helicase 158 319 2.4E-10 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 SUPERFAMILY SSF52540 170 399 2.79E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 SUPERFAMILY SSF52540 465 559 2.79E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 Pfam PF00271 Helicase conserved C-terminal domain 458 550 5.4E-6 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 Hamap MF_00983 Probable primosomal protein N' [priA]. 21 697 23.043 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 SMART SM00490 454 551 5.6E-7 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS01745 1b4e2e96880d8749045b82d2c8629978 697 TIGRFAM TIGR00595 priA: primosomal protein N' 175 695 1.7E-167 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 SMART SM00862 151 227 6.9E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 Gene3D G3DSA:1.10.10.10 125 231 2.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 Gene3D G3DSA:3.40.50.2300 1 124 4.8E-31 T 28-03-2018 AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 Pfam PF00072 Response regulator receiver domain 6 115 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 7.1E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 SUPERFAMILY SSF52172 7 186 5.55E-32 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS18310 7ec03f31b3335b77c5815b6f045836eb 234 SMART SM00448 1 114 5.1E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 SUPERFAMILY SSF51182 17 183 5.34E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 Gene3D G3DSA:1.10.10.60 215 259 2.4E-11 T 28-03-2018 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 Gene3D G3DSA:1.10.10.60 130 214 9.9E-13 T 28-03-2018 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 Pfam PF12833 Helix-turn-helix domain 180 258 2.8E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 240 2.0E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 256 2.0E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 SUPERFAMILY SSF46689 211 257 5.73E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 SMART SM00342 174 256 8.9E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17565 482efbfffaff08eaa0a8fc0280d68c18 259 Gene3D G3DSA:2.60.120.10 18 94 1.9E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS15845 65e5cce2a56f292c450330867806ef80 302 Pfam PF02687 FtsX-like permease family 206 299 8.3E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFA_RS15845 65e5cce2a56f292c450330867806ef80 302 PIRSF PIRSF003097 2 301 4.9E-53 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 AFA_RS05545 12180943cf610d882251d62c1d947def 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05545 12180943cf610d882251d62c1d947def 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05545 12180943cf610d882251d62c1d947def 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05545 12180943cf610d882251d62c1d947def 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05545 12180943cf610d882251d62c1d947def 307 Gene3D G3DSA:3.40.190.10 92 184 1.0E-18 T 28-03-2018 AFA_RS05545 12180943cf610d882251d62c1d947def 307 Gene3D G3DSA:3.40.190.10 185 268 1.4E-16 T 28-03-2018 AFA_RS05545 12180943cf610d882251d62c1d947def 307 SUPERFAMILY SSF53850 92 302 6.52E-37 T 28-03-2018 AFA_RS05545 12180943cf610d882251d62c1d947def 307 SUPERFAMILY SSF46785 4 113 2.02E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05545 12180943cf610d882251d62c1d947def 307 Gene3D G3DSA:1.10.10.10 1 87 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05545 12180943cf610d882251d62c1d947def 307 Pfam PF03466 LysR substrate binding domain 93 288 1.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 Pfam PF01965 DJ-1/PfpI family 2 177 3.8E-16 T 28-03-2018 IPR002818 DJ-1/PfpI AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 SMART SM00342 235 317 6.2E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 Gene3D G3DSA:1.10.10.60 274 323 1.5E-8 T 28-03-2018 AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 SUPERFAMILY SSF46689 270 321 1.03E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 Gene3D G3DSA:3.40.50.880 1 215 3.4E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 SUPERFAMILY SSF52317 1 196 1.27E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 Pfam PF12833 Helix-turn-helix domain 240 318 4.5E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS15460 a518502bb2bb171cc7a7b3df34fdf364 328 Gene3D G3DSA:1.10.10.60 216 273 7.9E-10 T 28-03-2018 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 PIRSF PIRSF036431 4 605 1.7E-178 T 28-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 SMART SM00388 377 445 1.2E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 597 7.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 SUPERFAMILY SSF55874 438 597 8.91E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 SMART SM00387 487 598 1.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 379 443 3.5E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Gene3D G3DSA:3.30.450.20 169 309 4.1E-6 T 28-03-2018 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 SUPERFAMILY SSF103190 61 192 3.4E-12 T 28-03-2018 IPR029151 Periplasmic sensor domain-like AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Gene3D G3DSA:1.10.287.130 330 441 1.0E-6 T 28-03-2018 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 595 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Gene3D G3DSA:3.30.450.20 62 168 5.7E-17 T 28-03-2018 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 SUPERFAMILY SSF47384 375 444 4.9E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS09150 d88ab8866e17626992c7702e603bf7ed 605 Gene3D G3DSA:3.30.565.10 449 604 1.6E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 Hamap MF_00318 Enolase [eno]. 2 412 44.43 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PIRSF PIRSF001400 1 426 9.9E-189 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 SUPERFAMILY SSF51604 139 427 1.98E-128 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 SMART SM01193 4 134 2.9E-91 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 ProSitePatterns PS00164 Enolase signature. 335 348 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 Gene3D G3DSA:3.30.390.10 3 126 2.9E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 SMART SM01192 139 426 1.3E-219 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 SUPERFAMILY SSF54826 4 136 3.76E-54 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 425 1.2E-130 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 37 51 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 335 349 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 107 123 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 161 174 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 312 323 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 PRINTS PR00148 Enolase signature 364 381 4.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 1.7E-206 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 Gene3D G3DSA:3.20.20.120 128 428 4.2E-102 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS12885 2998f8b214d47bc39cacadc70e32c930 428 Pfam PF03952 Enolase, N-terminal domain 4 133 5.9E-57 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS03015 635fb6fd4c067bbda39c988bfd89d9f0 252 SUPERFAMILY SSF88713 1 250 6.23E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS03015 635fb6fd4c067bbda39c988bfd89d9f0 252 Gene3D G3DSA:3.20.20.370 1 252 1.0E-44 T 28-03-2018 AFA_RS03015 635fb6fd4c067bbda39c988bfd89d9f0 252 Pfam PF04794 YdjC-like protein 1 246 9.8E-36 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 9.0E-7 T 28-03-2018 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 9.0E-7 T 28-03-2018 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 9.0E-7 T 28-03-2018 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 Gene3D G3DSA:1.20.1250.20 258 471 1.9E-23 T 28-03-2018 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 Gene3D G3DSA:1.20.1250.20 9 201 5.7E-28 T 28-03-2018 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 Pfam PF07690 Major Facilitator Superfamily 20 408 2.7E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 SUPERFAMILY SSF103473 1 202 5.62E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS00330 0ded898ef1d1e832eb0b97484de3f650 473 SUPERFAMILY SSF103473 248 462 5.62E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS01420 1f448b388e7c399e71070c459042013a 212 Pfam PF00857 Isochorismatase family 30 202 4.8E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PRINTS PR01398 Isochorismatase signature 61 78 2.3E-30 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PRINTS PR01398 Isochorismatase signature 2 14 2.3E-30 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PRINTS PR01398 Isochorismatase signature 186 203 2.3E-30 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PRINTS PR01398 Isochorismatase signature 112 134 2.3E-30 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PRINTS PR01398 Isochorismatase signature 168 186 2.3E-30 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 SUPERFAMILY SSF52499 11 210 6.15E-56 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 Gene3D G3DSA:3.40.50.850 1 211 1.8E-44 T 28-03-2018 AFA_RS01420 1f448b388e7c399e71070c459042013a 212 PIRSF PIRSF001111 1 212 6.3E-93 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 AFA_RS08090 637b49f89950d6f71b3e2ca1308e8e21 136 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 1.2E-7 T 28-03-2018 AFA_RS08090 637b49f89950d6f71b3e2ca1308e8e21 136 Gene3D G3DSA:3.10.180.10 2 134 1.4E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS08090 637b49f89950d6f71b3e2ca1308e8e21 136 SUPERFAMILY SSF54593 5 133 5.23E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS08090 637b49f89950d6f71b3e2ca1308e8e21 136 ProSitePatterns PS00934 Glyoxalase I signature 1. 10 30 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 Gene3D G3DSA:3.40.1280.10 1 155 1.8E-51 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 28.148 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 SUPERFAMILY SSF75217 1 154 8.37E-48 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 PIRSF PIRSF004505 1 155 9.4E-45 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 155 5.8E-46 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS12725 49315a99abec22a6a5f8be0cf5ca9830 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 1.2E-48 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 SUPERFAMILY SSF47384 210 292 1.18E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Pfam PF08521 Two-component sensor kinase N-terminal 8 150 8.2E-24 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Gene3D G3DSA:1.10.287.130 217 282 5.0E-14 T 28-03-2018 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 291 1.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Gene3D G3DSA:1.20.5.1040 132 174 0.025 T 28-03-2018 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Gene3D G3DSA:1.20.5.1040 1 43 0.46 T 28-03-2018 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Gene3D G3DSA:3.30.565.10 283 453 1.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 SUPERFAMILY SSF55874 283 450 9.69E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 SMART SM00388 227 292 1.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 SMART SM00387 340 452 2.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11015 b922c6e7ad364cdce82a2a90b2928e94 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 449 4.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 5.9E-46 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 SUPERFAMILY SSF54862 36 145 9.21E-26 T 28-03-2018 AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 27.689 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 Gene3D G3DSA:3.30.70.20 107 154 1.5E-5 T 28-03-2018 AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 7.6E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 Gene3D G3DSA:3.30.70.20 39 73 4.6E-7 T 28-03-2018 AFA_RS13380 01a281e5ac6751bd0f8b433a58ce1a0e 162 Gene3D G3DSA:3.30.70.20 74 106 5.7E-13 T 28-03-2018 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 68 708 1.0E-106 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 Gene3D G3DSA:2.40.170.20 180 708 4.9E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 SUPERFAMILY SSF56935 24 708 2.5E-98 T 28-03-2018 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 162 1.3E-9 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 691 708 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS00765 192078fae9943d947cc4be15ef355780 708 Pfam PF00593 TonB dependent receptor 295 707 6.9E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS00765 192078fae9943d947cc4be15ef355780 708 Gene3D G3DSA:2.170.130.10 21 179 4.5E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 Gene3D G3DSA:3.40.190.10 94 187 2.2E-18 T 28-03-2018 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 Gene3D G3DSA:3.40.190.10 188 273 3.0E-13 T 28-03-2018 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 SUPERFAMILY SSF53850 94 304 8.33E-34 T 28-03-2018 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 Pfam PF03466 LysR substrate binding domain 93 301 4.2E-37 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 SUPERFAMILY SSF46785 7 117 1.69E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 3.5E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04285 2bf6b004a4ac45fd5e3d91728a152dfa 319 Gene3D G3DSA:1.10.10.10 2 89 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Gene3D G3DSA:1.10.275.10 18 122 1.2E-35 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 117 139 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 326 345 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 158 178 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 209 225 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 291 307 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00145 Argininosuccinate lyase family signature 247 271 1.4E-67 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 ProSitePatterns PS00163 Fumarate lyases signature. 291 300 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00149 Fumarate lyase superfamily signature 291 307 2.4E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 2.4E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00149 Fumarate lyase superfamily signature 118 136 2.4E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 PRINTS PR00149 Fumarate lyase superfamily signature 247 274 2.4E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Hamap MF_00006 Argininosuccinate lyase [argH]. 18 469 42.674 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Gene3D G3DSA:1.20.200.10 123 390 4.2E-100 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Pfam PF00206 Lyase 23 316 1.4E-77 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Gene3D G3DSA:1.10.40.30 391 448 4.4E-27 T 28-03-2018 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 TIGRFAM TIGR00838 argH: argininosuccinate lyase 20 462 1.4E-185 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 Pfam PF14698 Argininosuccinate lyase C-terminal 379 447 7.1E-25 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS10550 38095896bc20985b3e206d066ef3ceff 473 SUPERFAMILY SSF48557 20 466 1.23E-148 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS08525 513ea82d701cbd6ed279c3badb33bcdd 501 Pfam PF04945 YHS domain 416 449 4.4E-11 T 28-03-2018 IPR007029 YHS domain AFA_RS08525 513ea82d701cbd6ed279c3badb33bcdd 501 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 21 248 5.2E-69 T 28-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 AFA_RS08525 513ea82d701cbd6ed279c3badb33bcdd 501 SUPERFAMILY SSF47240 4 498 1.83E-163 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS08525 513ea82d701cbd6ed279c3badb33bcdd 501 Gene3D G3DSA:1.10.620.20 1 501 1.7E-171 T 28-03-2018 AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 SUPERFAMILY SSF51735 3 220 2.87E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 Pfam PF00106 short chain dehydrogenase 3 188 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS12900 918b6442f6821da1d02eb83cb64d2406 241 Gene3D G3DSA:3.40.50.720 1 235 3.1E-34 T 28-03-2018 AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 Pfam PF00437 Type II/IV secretion system protein 18 315 3.4E-49 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 Gene3D G3DSA:3.40.50.300 148 327 1.4E-13 T 28-03-2018 AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 Gene3D G3DSA:3.30.450.90 11 115 1.4E-13 T 28-03-2018 AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 22 325 4.8E-91 T 28-03-2018 IPR014155 Type IV secretion system protein VirB11 GO:0005737|GO:0006810|GO:0009405 AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 SUPERFAMILY SSF52540 10 118 6.1E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12190 0a5ce945916708b8dcae7ff17a722fa4 334 SUPERFAMILY SSF52540 147 297 6.1E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 SUPERFAMILY SSF52518 369 570 2.58E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 1.2E-51 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Gene3D G3DSA:3.40.50.970 360 582 2.8E-40 T 28-03-2018 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Gene3D G3DSA:3.40.50.970 1 192 1.7E-48 T 28-03-2018 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 552 1.6E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 SUPERFAMILY SSF52518 1 182 2.43E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 590 0.0 T 28-03-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Gene3D G3DSA:3.40.50.1220 193 359 1.6E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 327 7.3E-33 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFA_RS02665 ad79dfa1d392c958adf4050b55890b01 591 SUPERFAMILY SSF52467 186 376 2.7E-44 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS08350 0a14d4d73ef76d4e0259dec34e332d19 438 Gene3D G3DSA:1.20.1250.20 239 437 7.8E-20 T 28-03-2018 AFA_RS08350 0a14d4d73ef76d4e0259dec34e332d19 438 SUPERFAMILY SSF103473 21 433 5.89E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS08350 0a14d4d73ef76d4e0259dec34e332d19 438 Gene3D G3DSA:1.20.1250.20 19 228 1.9E-36 T 28-03-2018 AFA_RS08350 0a14d4d73ef76d4e0259dec34e332d19 438 Pfam PF07690 Major Facilitator Superfamily 33 381 2.7E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 64 72 7.4E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 147 163 7.4E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 111 126 7.4E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 ProSitePatterns PS00855 Signal peptidases II signature. 114 126 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 TIGRFAM TIGR00077 lspA: signal peptidase II 17 174 1.2E-39 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 18 172 16.436 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS07505 d69f0144ce9d9a730e93c99226e5cd6f 177 Pfam PF01252 Signal peptidase (SPase) II 27 166 9.9E-38 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Gene3D G3DSA:3.40.50.980 20 198 2.0E-37 T 28-03-2018 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Gene3D G3DSA:3.40.50.980 199 354 3.6E-31 T 28-03-2018 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Gene3D G3DSA:3.30.300.30 446 550 1.7E-29 T 28-03-2018 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Gene3D G3DSA:2.30.38.10 370 445 6.5E-18 T 28-03-2018 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 534 1.1E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 Pfam PF00501 AMP-binding enzyme 26 451 1.1E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS10730 0fcd008d272c7875d1c7605b2d71bce5 550 SUPERFAMILY SSF56801 12 546 9.68E-136 T 28-03-2018 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF01225 Mur ligase family, catalytic domain 492 536 4.5E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF01225 Mur ligase family, catalytic domain 20 91 1.7E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF08245 Mur ligase middle domain 103 304 7.3E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF08245 Mur ligase middle domain 571 761 1.1E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF63418 491 563 3.01E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF53244 325 485 1.98E-39 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 19 484 1.6E-138 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF53623 565 780 7.59E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.40.1190.10 94 328 5.3E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 31.343 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF53244 781 911 3.2E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 462 912 32.413 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF63418 16 92 1.44E-17 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 494 911 2.7E-133 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.40.1390.10 487 555 3.4E-20 T 28-03-2018 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.40.1390.10 2 93 2.4E-18 T 28-03-2018 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 SUPERFAMILY SSF53623 94 322 4.19E-68 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.40.1190.10 556 777 4.1E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 419 2.8E-18 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Pfam PF02875 Mur ligase family, glutamate ligase domain 781 862 1.2E-16 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.90.190.20 781 924 4.7E-44 T 28-03-2018 AFA_RS03645 1f5e345681aa3369bd087568ba48ce40 925 Gene3D G3DSA:3.90.190.20 329 486 8.0E-41 T 28-03-2018 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 762 37.471 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 PIRSF PIRSF000382 1 763 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 761 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 SUPERFAMILY SSF51726 5 398 1.44E-113 T 28-03-2018 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 Gene3D G3DSA:3.20.20.210 2 393 4.5E-153 T 28-03-2018 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 435 757 3.5E-157 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 Gene3D G3DSA:3.20.20.210 394 762 2.7E-129 T 28-03-2018 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 SUPERFAMILY SSF51726 400 760 2.49E-117 T 28-03-2018 AFA_RS07965 f26d64aa03885ebed87834151715ca7d 763 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 319 3.5E-118 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS04075 74fb9552f60e033627112b3f9a78512b 884 Gene3D G3DSA:3.40.50.300 143 563 1.2E-12 T 28-03-2018 AFA_RS04075 74fb9552f60e033627112b3f9a78512b 884 SUPERFAMILY SSF52540 217 563 2.12E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04075 74fb9552f60e033627112b3f9a78512b 884 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 20 870 4.4E-195 T 28-03-2018 IPR019925 DNA repair protein, predicted AFA_RS04075 74fb9552f60e033627112b3f9a78512b 884 Gene3D G3DSA:3.90.320.10 564 787 3.8E-8 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 Gene3D G3DSA:3.90.1150.10 274 412 4.5E-59 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 PIRSF PIRSF000412 1 415 4.8E-164 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 SUPERFAMILY SSF53383 6 413 1.02E-177 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 Gene3D G3DSA:3.40.640.10 37 273 2.1E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 52.19 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS15480 100774f93b666147af5985f2ab4750b4 416 Pfam PF00464 Serine hydroxymethyltransferase 8 382 1.1E-168 T 28-03-2018 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 4 18 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 18 34 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 34 46 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 ProSitePatterns PS00622 LuxR-type HTH domain signature. 18 45 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 SMART SM00421 1 58 5.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 SUPERFAMILY SSF46894 3 65 2.82E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 Pfam PF00196 Bacterial regulatory proteins, luxR family 4 58 6.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS01825 50946665416bde408934f6a51d45a13d 91 Gene3D G3DSA:1.10.10.10 1 68 5.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 PIRSF PIRSF001220 3 328 1.6E-82 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 Gene3D G3DSA:3.40.50.40 218 329 8.9E-24 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 Gene3D G3DSA:3.40.50.1170 3 214 1.0E-50 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 5 329 1.0E-103 T 28-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 PRINTS PR00139 Asparaginase/glutaminase family signature 265 283 3.0E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 PRINTS PR00139 Asparaginase/glutaminase family signature 86 104 3.0E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 3.0E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 PIRSF PIRSF500176 4 328 9.6E-73 T 28-03-2018 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 SMART SM00870 6 323 4.5E-112 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 SUPERFAMILY SSF53774 5 328 1.05E-87 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 Pfam PF00710 Asparaginase, N-terminal 7 194 3.6E-52 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AFA_RS01040 81d98c7593a7d035d6a81e390f904bf8 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 87 97 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 AFA_RS00155 f9dd284b920ee7c97e3bfcb1ee15e7d0 322 PIRSF PIRSF017082 1 320 2.8E-69 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00155 f9dd284b920ee7c97e3bfcb1ee15e7d0 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 1.4E-67 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00155 f9dd284b920ee7c97e3bfcb1ee15e7d0 322 Gene3D G3DSA:3.40.190.10 120 230 4.7E-10 T 28-03-2018 AFA_RS00155 f9dd284b920ee7c97e3bfcb1ee15e7d0 322 SUPERFAMILY SSF53850 110 280 3.69E-9 T 28-03-2018 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 Gene3D G3DSA:2.60.300.12 17 122 4.1E-38 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 17 117 5.5E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 SUPERFAMILY SSF89360 17 111 3.73E-30 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 121 3.0E-37 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFA_RS15515 8230c18e8b9461720228cc4bf0aa2c1c 122 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 122 36.241 T 28-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 AFA_RS13685 4979cbd43083a64351a4edc45b896f7e 317 Gene3D G3DSA:3.90.1210.10 50 112 1.1E-11 T 28-03-2018 AFA_RS13685 4979cbd43083a64351a4edc45b896f7e 317 SMART SM00858 51 111 7.1E-8 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFA_RS13685 4979cbd43083a64351a4edc45b896f7e 317 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 11 311 8.6E-46 T 28-03-2018 IPR017592 Pilus assembly, Flp-type CpaB AFA_RS13685 4979cbd43083a64351a4edc45b896f7e 317 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 113 226 5.2E-27 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain AFA_RS13685 4979cbd43083a64351a4edc45b896f7e 317 Pfam PF08666 SAF domain 53 108 3.6E-8 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 Gene3D G3DSA:3.20.20.140 12 351 5.5E-52 T 28-03-2018 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 ProSitePatterns PS00483 Dihydroorotase signature 2. 253 264 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 ProSitePatterns PS00482 Dihydroorotase signature 1. 15 23 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 SUPERFAMILY SSF51556 6 350 1.27E-137 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 350 1.4E-137 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 Pfam PF01979 Amidohydrolase family 15 316 1.0E-19 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 PIRSF PIRSF001237 4 352 2.3E-137 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS14465 17461e1f747726e1ee922514396b1e1f 352 Hamap MF_00219 Dihydroorotase [pyrC]. 6 351 44.242 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS06555 31ccf289fa9ec501d150b5b4afa75ccf 444 Gene3D G3DSA:3.40.309.10 231 402 7.1E-25 T 28-03-2018 AFA_RS06555 31ccf289fa9ec501d150b5b4afa75ccf 444 Pfam PF00171 Aldehyde dehydrogenase family 12 400 3.2E-26 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS06555 31ccf289fa9ec501d150b5b4afa75ccf 444 Gene3D G3DSA:3.40.605.10 3 230 3.0E-24 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS06555 31ccf289fa9ec501d150b5b4afa75ccf 444 SUPERFAMILY SSF53720 18 442 1.44E-58 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 SUPERFAMILY SSF69742 5 160 3.53E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Gene3D G3DSA:3.40.50.720 163 315 2.7E-22 T 28-03-2018 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 408 1.2E-124 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 306 3.1E-42 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 417 28.749 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Gene3D G3DSA:1.10.1200.70 334 417 5.3E-21 T 28-03-2018 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 158 1.2E-46 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 416 3.3E-24 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 PIRSF PIRSF000445 3 424 4.0E-144 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 SUPERFAMILY SSF51735 165 317 1.4E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16680 00e139a806303e61c2aeacbf4ac50349 424 SUPERFAMILY SSF69075 319 417 4.84E-24 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 SMART SM00738 2 111 5.5E-45 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 SUPERFAMILY SSF50104 121 176 4.0E-20 T 28-03-2018 IPR008991 Translation protein SH3-like domain AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 Gene3D G3DSA:2.30.30.30 118 177 3.4E-22 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 SMART SM00739 123 150 6.2E-6 T 28-03-2018 IPR005824 KOW AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 SUPERFAMILY SSF82679 3 113 1.31E-37 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 7.8E-70 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 3.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 3.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 3.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.639 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 Pfam PF00467 KOW motif 126 158 1.3E-7 T 28-03-2018 IPR005824 KOW AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 Pfam PF02357 Transcription termination factor nusG 3 108 7.1E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFA_RS18370 ca4d25fb4edff427696127ac2e7858ed 177 Gene3D G3DSA:3.30.70.940 2 115 1.0E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 3.5E-36 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 3.5E-36 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 3.5E-36 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 3.5E-36 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.5E-36 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 6.3E-126 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 353 6.4E-126 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 Gene3D G3DSA:3.40.1690.10 218 353 6.2E-58 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFA_RS05780 07471d652fd7928c7d56f599b1ed2fc8 386 SUPERFAMILY SSF160544 244 351 3.53E-40 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFA_RS11975 b3056708c404069a74d289078b0a5f1c 294 Gene3D G3DSA:3.40.50.720 10 177 3.9E-30 T 28-03-2018 AFA_RS11975 b3056708c404069a74d289078b0a5f1c 294 SUPERFAMILY SSF48179 179 287 6.46E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS11975 b3056708c404069a74d289078b0a5f1c 294 Pfam PF02153 Prephenate dehydrogenase 23 278 1.4E-70 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AFA_RS11975 b3056708c404069a74d289078b0a5f1c 294 SUPERFAMILY SSF51735 10 176 1.54E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS11975 b3056708c404069a74d289078b0a5f1c 294 Gene3D G3DSA:1.10.3660.10 187 292 2.8E-26 T 28-03-2018 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Gene3D G3DSA:3.30.1360.10 9 64 1.6E-12 T 28-03-2018 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 150 6.5E-24 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 306 9.7E-25 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Gene3D G3DSA:2.170.120.12 65 173 2.0E-40 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 SUPERFAMILY SSF56553 50 174 3.66E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 SMART SM00662 20 230 7.2E-98 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 324 1.0E-34 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 SUPERFAMILY SSF55257 175 228 1.57E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 SUPERFAMILY SSF55257 4 50 1.57E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 314 1.4E-106 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 223 7.2E-23 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 315 35.678 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 SUPERFAMILY SSF47789 249 321 1.06E-26 T 28-03-2018 AFA_RS17970 c3b812feaddc9242d33e590e63e11374 327 Gene3D G3DSA:1.10.150.20 244 326 8.8E-28 T 28-03-2018 AFA_RS17625 8ab616e8bcc9bb788c6870efd60a1b26 87 SMART SM00834 2 42 3.0E-11 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS17625 8ab616e8bcc9bb788c6870efd60a1b26 87 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 52 9.2E-18 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS17625 8ab616e8bcc9bb788c6870efd60a1b26 87 Pfam PF09723 Zinc ribbon domain 2 41 2.0E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 Gene3D G3DSA:3.40.50.300 352 564 2.0E-20 T 28-03-2018 AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 Pfam PF02562 PhoH-like protein 349 563 4.8E-54 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 Gene3D G3DSA:3.40.50.1010 106 351 4.5E-38 T 28-03-2018 IPR029060 PIN domain-like AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 SUPERFAMILY SSF88723 108 169 1.47E-11 T 28-03-2018 IPR029060 PIN domain-like AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 SUPERFAMILY SSF88723 204 254 1.47E-11 T 28-03-2018 IPR029060 PIN domain-like AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 SUPERFAMILY SSF52540 348 434 1.39E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 SUPERFAMILY SSF52540 476 551 1.39E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 Pfam PF13638 PIN domain 110 254 1.8E-37 T 28-03-2018 IPR002716 PIN domain AFA_RS05230 0f8e3128fa8f2d86c516f96da4809e05 571 SMART SM00670 108 241 3.7E-10 T 28-03-2018 IPR002716 PIN domain AFA_RS07725 4c7050faae503db00e4fb7d2850eddd7 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.4E-20 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS07725 4c7050faae503db00e4fb7d2850eddd7 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFA_RS07725 4c7050faae503db00e4fb7d2850eddd7 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 1.6E-33 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFA_RS07725 4c7050faae503db00e4fb7d2850eddd7 107 Gene3D G3DSA:2.60.300.12 2 107 5.0E-35 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS07725 4c7050faae503db00e4fb7d2850eddd7 107 SUPERFAMILY SSF89360 1 96 5.62E-30 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Pfam PF14759 Reductase C-terminal 328 415 2.7E-16 T 28-03-2018 IPR028202 Reductase, C-terminal AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Gene3D G3DSA:3.30.390.30 327 424 3.5E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.7E-21 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-21 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 1.7E-21 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.7E-21 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.7E-21 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Gene3D G3DSA:3.50.50.60 126 244 2.0E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 SUPERFAMILY SSF51905 1 319 2.51E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 309 1.5E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Gene3D G3DSA:3.50.50.60 1 125 1.0E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 SUPERFAMILY SSF55424 321 418 1.03E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-16 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 1.2E-16 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 1.2E-16 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 1.2E-16 T 28-03-2018 AFA_RS15105 5374923158e7d2a729bd19ca91d6be40 425 Gene3D G3DSA:3.50.50.60 246 326 5.8E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10590 228a44b670ca9a733fdcb301eb354f40 246 SUPERFAMILY SSF64167 1 245 1.31E-83 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFA_RS10590 228a44b670ca9a733fdcb301eb354f40 246 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 246 37.015 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFA_RS10590 228a44b670ca9a733fdcb301eb354f40 246 Gene3D G3DSA:3.40.1210.10 1 246 4.3E-83 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFA_RS10590 228a44b670ca9a733fdcb301eb354f40 246 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 8.0E-64 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFA_RS10590 228a44b670ca9a733fdcb301eb354f40 246 Pfam PF01975 Survival protein SurE 3 182 5.8E-59 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 Gene3D G3DSA:3.30.930.10 8 340 7.4E-84 T 28-03-2018 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 7.6E-20 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 45.115 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 SUPERFAMILY SSF46589 17 100 5.07E-18 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 4.0E-92 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 SUPERFAMILY SSF55681 93 339 9.95E-73 T 28-03-2018 AFA_RS08730 f29ba75f1895e96b4a9a464adc6ed52f 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 339 6.0E-95 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 Pfam PF00990 Diguanylate cyclase, GGDEF domain 524 674 5.6E-25 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 SMART SM00052 693 939 1.5E-62 T 28-03-2018 IPR001633 EAL domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 SMART SM00267 512 682 8.7E-32 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 Pfam PF00563 EAL domain 707 933 1.4E-57 T 28-03-2018 IPR001633 EAL domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 SUPERFAMILY SSF141868 707 941 4.05E-66 T 28-03-2018 IPR001633 EAL domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 Gene3D G3DSA:3.20.20.450 669 942 3.2E-68 T 28-03-2018 IPR001633 EAL domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 Gene3D G3DSA:3.30.450.20 395 512 4.7E-7 T 28-03-2018 AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 521 673 5.5E-22 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 Gene3D G3DSA:3.30.70.270 513 668 2.1E-37 T 28-03-2018 AFA_RS17910 79db0182a6115e194b95b03f8d7c191a 970 SUPERFAMILY SSF55073 529 681 5.73E-29 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 698 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SMART SM00889 485 604 1.1E-74 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SUPERFAMILY SSF52540 6 288 1.13E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SUPERFAMILY SSF54211 484 605 3.54E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Gene3D G3DSA:3.30.230.10 499 614 4.6E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Gene3D G3DSA:3.30.70.870 407 498 9.5E-39 T 28-03-2018 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 108.683 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 3.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 3.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 3.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Gene3D G3DSA:3.30.70.240 615 693 1.5E-30 T 28-03-2018 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Gene3D G3DSA:2.40.30.10 295 406 1.1E-30 T 28-03-2018 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Pfam PF03764 Elongation factor G, domain IV 484 604 9.9E-49 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Pfam PF14492 Elongation Factor G, domain II 409 483 3.1E-34 T 28-03-2018 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 3.9E-30 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SUPERFAMILY SSF50447 271 409 4.24E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Pfam PF00679 Elongation factor G C-terminus 606 693 1.9E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SMART SM00838 606 694 5.6E-54 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.8E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SUPERFAMILY SSF54980 609 696 6.23E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 8.5E-64 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 SUPERFAMILY SSF54980 407 485 4.32E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS18295 aa63347d9ae6cb4130f201ee9aa852dd 700 Gene3D G3DSA:3.40.50.300 1 293 8.6E-56 T 28-03-2018 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 Pfam PF03466 LysR substrate binding domain 88 287 5.4E-46 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.0E-26 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 Gene3D G3DSA:1.10.10.10 1 83 3.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 SUPERFAMILY SSF46785 3 86 3.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 SUPERFAMILY SSF53850 90 291 6.4E-44 T 28-03-2018 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 Gene3D G3DSA:3.40.190.10 178 264 5.0E-20 T 28-03-2018 AFA_RS02875 e4941f4ecb2ae2ac09931cbccffb0f7a 295 Gene3D G3DSA:3.40.190.10 88 177 3.9E-24 T 28-03-2018 AFA_RS07490 278fdbb75cf6848eaf243635bc35cb19 331 Pfam PF05971 Protein of unknown function (DUF890) 20 318 1.7E-129 T 28-03-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 AFA_RS07490 278fdbb75cf6848eaf243635bc35cb19 331 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 20 320 54.504 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 AFA_RS07490 278fdbb75cf6848eaf243635bc35cb19 331 Gene3D G3DSA:3.40.50.150 53 318 7.4E-53 T 28-03-2018 AFA_RS07490 278fdbb75cf6848eaf243635bc35cb19 331 PIRSF PIRSF029038 9 330 1.0E-150 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 AFA_RS07490 278fdbb75cf6848eaf243635bc35cb19 331 SUPERFAMILY SSF53335 58 317 3.73E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 286 300 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 82 95 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 133 148 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 209 222 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 400 413 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 119 132 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 108 116 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 195 208 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 PRINTS PR00415 Aconitase family signature 343 354 3.9E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 Gene3D G3DSA:3.40.1060.10 155 288 2.6E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 Gene3D G3DSA:3.30.499.10 323 467 9.0E-52 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.843 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 5.6E-159 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 466 1.1E-240 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 Gene3D G3DSA:3.30.499.10 1 154 2.8E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 SUPERFAMILY SSF53732 2 466 8.76E-168 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10805 80c8133672f6bf783c9f14ec073e642f 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 1.3E-4 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 4.0E-13 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 SUPERFAMILY SSF51161 2 256 9.56E-73 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 55.501 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Gene3D G3DSA:1.10.166.10 3 69 4.8E-28 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 271 1.2E-138 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 1.8E-25 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 AFA_RS07575 c22e63c61ba3a69b1bfc4728abf3abf8 272 Gene3D G3DSA:2.160.10.10 87 257 2.9E-36 T 28-03-2018 AFA_RS01055 d744265dd5252d09e098f9beaf6f0ba0 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 258 5.4E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01055 d744265dd5252d09e098f9beaf6f0ba0 269 Gene3D G3DSA:3.40.190.10 156 269 2.3E-10 T 28-03-2018 AFA_RS01055 d744265dd5252d09e098f9beaf6f0ba0 269 SMART SM00062 25 260 5.5E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01055 d744265dd5252d09e098f9beaf6f0ba0 269 Gene3D G3DSA:3.40.190.10 21 155 1.0E-31 T 28-03-2018 AFA_RS01055 d744265dd5252d09e098f9beaf6f0ba0 269 SUPERFAMILY SSF53850 7 260 3.16E-58 T 28-03-2018 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 Gene3D G3DSA:3.40.50.2300 2 124 8.1E-36 T 28-03-2018 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 3.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 Gene3D G3DSA:1.10.10.10 125 232 4.0E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 Pfam PF00072 Response regulator receiver domain 5 117 2.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 SMART SM00862 150 225 2.3E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 SUPERFAMILY SSF46894 123 226 1.02E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 SMART SM00448 3 116 3.9E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 SUPERFAMILY SSF52172 2 126 3.13E-43 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS16225 f2179ecb8a75b0be601de9be83bd0da0 236 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 225 8.6E-111 T 28-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 Pfam PF12833 Helix-turn-helix domain 245 322 1.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 SMART SM00342 239 324 2.6E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 320 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 SUPERFAMILY SSF46689 275 322 8.38E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 SUPERFAMILY SSF46689 222 273 8.98E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 Gene3D G3DSA:1.10.10.60 219 277 1.2E-11 T 28-03-2018 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 Gene3D G3DSA:1.10.10.60 278 326 1.0E-7 T 28-03-2018 AFA_RS06520 e46d26f1ee776cfba48fe1d8409716c4 328 Pfam PF14525 AraC-binding-like domain 35 200 5.2E-31 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS04025 f146604161b744ace8c8f607f074805f 129 Pfam PF01638 HxlR-like helix-turn-helix 31 115 3.1E-27 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type AFA_RS04025 f146604161b744ace8c8f607f074805f 129 SUPERFAMILY SSF46785 18 123 1.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04025 f146604161b744ace8c8f607f074805f 129 Gene3D G3DSA:1.10.10.10 13 126 1.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SMART SM00062 27 242 3.1E-15 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Gene3D G3DSA:3.30.70.270 439 597 1.2E-55 T 28-03-2018 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Gene3D G3DSA:3.40.190.10 134 200 2.0E-5 T 28-03-2018 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Pfam PF08448 PAS fold 302 413 1.3E-11 T 28-03-2018 IPR013656 PAS fold-4 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SUPERFAMILY SSF53850 28 247 5.2E-33 T 28-03-2018 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 234 3.8E-23 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SMART SM00267 411 589 3.2E-54 T 28-03-2018 IPR000160 GGDEF domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SUPERFAMILY SSF55073 428 591 1.8E-45 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Gene3D G3DSA:3.20.20.450 598 853 1.1E-86 T 28-03-2018 IPR001633 EAL domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Gene3D G3DSA:3.30.450.20 292 438 4.5E-15 T 28-03-2018 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Pfam PF00563 EAL domain 606 836 3.3E-64 T 28-03-2018 IPR001633 EAL domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Pfam PF00990 Diguanylate cyclase, GGDEF domain 423 585 1.3E-44 T 28-03-2018 IPR000160 GGDEF domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SMART SM00052 599 841 2.2E-89 T 28-03-2018 IPR001633 EAL domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 422 588 5.0E-38 T 28-03-2018 IPR000160 GGDEF domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SUPERFAMILY SSF141868 605 846 7.85E-79 T 28-03-2018 IPR001633 EAL domain AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 Gene3D G3DSA:3.40.190.10 13 133 9.4E-14 T 28-03-2018 AFA_RS01010 756863b576c14074bef6bc54c46a1176 854 SUPERFAMILY SSF55785 284 404 2.44E-13 T 28-03-2018 IPR000014 PAS domain AFA_RS08680 18083468a6e8892d94ed90726f02615d 135 Pfam PF03610 PTS system fructose IIA component 6 111 1.4E-13 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 AFA_RS08680 18083468a6e8892d94ed90726f02615d 135 SUPERFAMILY SSF53062 3 132 1.02E-21 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 AFA_RS08680 18083468a6e8892d94ed90726f02615d 135 Gene3D G3DSA:3.40.50.510 2 133 3.4E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 Gene3D G3DSA:3.40.190.10 139 223 4.3E-17 T 28-03-2018 AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 15 286 6.9E-91 T 28-03-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 SMART SM00062 39 271 5.0E-41 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 SUPERFAMILY SSF53850 30 266 1.87E-42 T 28-03-2018 AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 267 4.5E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS12585 3405f9a8e92f4ba6d4b2a2fe818df3ce 288 Gene3D G3DSA:3.40.190.10 29 138 4.0E-25 T 28-03-2018 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 Gene3D G3DSA:2.40.30.10 1 102 4.3E-10 T 28-03-2018 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 SUPERFAMILY SSF63380 3 103 3.93E-12 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 Gene3D G3DSA:3.40.50.80 111 241 9.6E-19 T 28-03-2018 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 Gene3D G3DSA:3.10.20.30 242 349 5.6E-21 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 SUPERFAMILY SSF54292 234 346 9.44E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 265 337 1.2E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 Pfam PF00175 Oxidoreductase NAD-binding domain 118 225 9.5E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 295 303 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS14085 f3a42c9a6fed28f39ef0a9048f665528 350 SUPERFAMILY SSF52343 112 245 2.62E-16 T 28-03-2018 AFA_RS16945 e9510c69abef8b90a95ef00efd7ccda0 103 Gene3D G3DSA:2.10.260.10 19 57 3.0E-4 T 28-03-2018 AFA_RS16945 e9510c69abef8b90a95ef00efd7ccda0 103 SUPERFAMILY SSF89447 18 74 1.52E-6 T 28-03-2018 AFA_RS18510 a15bc5ce399ffb1c6bdeb051dcac79f5 324 Gene3D G3DSA:3.40.50.1100 4 159 1.2E-32 T 28-03-2018 AFA_RS18510 a15bc5ce399ffb1c6bdeb051dcac79f5 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 305 2.1E-67 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS18510 a15bc5ce399ffb1c6bdeb051dcac79f5 324 SUPERFAMILY SSF53686 8 312 2.88E-78 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS18510 a15bc5ce399ffb1c6bdeb051dcac79f5 324 Gene3D G3DSA:3.40.50.1100 160 323 3.8E-35 T 28-03-2018 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Gene3D G3DSA:3.40.50.980 190 345 4.1E-34 T 28-03-2018 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Pfam PF00501 AMP-binding enzyme 17 440 3.5E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Gene3D G3DSA:3.30.300.30 434 539 8.9E-26 T 28-03-2018 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 SUPERFAMILY SSF56801 4 537 1.27E-132 T 28-03-2018 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 524 3.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Gene3D G3DSA:3.40.50.980 8 189 1.8E-34 T 28-03-2018 AFA_RS15375 cf4f3966b99012f0fb40b418a4127270 548 Gene3D G3DSA:2.30.38.10 346 433 3.7E-16 T 28-03-2018 AFA_RS00520 469f1267a64dc8a44168e688c8ba89b3 281 Gene3D G3DSA:3.40.190.10 125 265 9.3E-32 T 28-03-2018 AFA_RS00520 469f1267a64dc8a44168e688c8ba89b3 281 SUPERFAMILY SSF53850 28 264 1.16E-61 T 28-03-2018 AFA_RS00520 469f1267a64dc8a44168e688c8ba89b3 281 Pfam PF03180 NLPA lipoprotein 28 261 6.7E-67 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS00520 469f1267a64dc8a44168e688c8ba89b3 281 Gene3D G3DSA:3.40.190.10 27 124 4.8E-20 T 28-03-2018 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 Gene3D G3DSA:3.40.718.10 1 358 3.7E-123 T 28-03-2018 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 1.2E-144 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 4.0E-132 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 SUPERFAMILY SSF53659 1 357 7.92E-122 T 28-03-2018 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 50.791 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 SMART SM01329 4 353 5.8E-204 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS10795 3ba181267dfba14a4363acaaccc1a1db 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 Gene3D G3DSA:3.20.20.70 2 317 4.1E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 TIGRFAM TIGR00874 talAB: transaldolase 4 315 1.0E-129 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 ProSitePatterns PS00958 Transaldolase active site. 123 140 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 Hamap MF_00492 Transaldolase [tal]. 2 317 46.642 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 310 3.3E-91 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 AFA_RS04120 8c927bffcd6e2c029cedafcd76dbffc3 320 SUPERFAMILY SSF51569 1 316 3.45E-102 T 28-03-2018 AFA_RS15915 3a121551c733ab87ab4018bf76a5eca6 264 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 258 2.6E-68 T 28-03-2018 AFA_RS15915 3a121551c733ab87ab4018bf76a5eca6 264 SUPERFAMILY SSF56219 2 261 6.28E-72 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS15915 3a121551c733ab87ab4018bf76a5eca6 264 Gene3D G3DSA:3.60.10.10 1 264 1.1E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS15915 3a121551c733ab87ab4018bf76a5eca6 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 253 1.1E-17 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS15915 3a121551c733ab87ab4018bf76a5eca6 264 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 260 2.8E-73 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 SUPERFAMILY SSF143034 2 64 2.22E-23 T 28-03-2018 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-18 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.565 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 Pfam PF01632 Ribosomal protein L35 2 62 2.2E-25 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS08720 8e50ac70a35cbe62a141861760e0c586 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.1E-26 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 SUPERFAMILY SSF54211 3 124 1.97E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 44.688 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 SUPERFAMILY SSF54211 134 280 1.59E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 Gene3D G3DSA:3.30.1700.10 128 302 8.1E-66 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 Gene3D G3DSA:3.30.230.20 1 127 9.4E-47 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3 301 2.8E-118 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03695 6ddaf7a3ae18960d4d87c19d27f171cf 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 6.8E-105 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS01315 724e10e3b30bdd61c08b993cd69c22f4 300 Pfam PF01136 Peptidase family U32 93 259 3.7E-13 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFA_RS00595 e5fb4280607dfaf9694afcff097bf971 341 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 273 1.4E-61 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS00595 e5fb4280607dfaf9694afcff097bf971 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 321 1.1E-74 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS00595 e5fb4280607dfaf9694afcff097bf971 341 Gene3D G3DSA:3.40.190.10 149 338 0.037 T 28-03-2018 AFA_RS00595 e5fb4280607dfaf9694afcff097bf971 341 PIRSF PIRSF006470 1 338 1.5E-85 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 Pfam PF02796 Helix-turn-helix domain of resolvase 141 184 1.5E-11 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 SUPERFAMILY SSF53041 6 139 5.62E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 Pfam PF00239 Resolvase, N terminal domain 6 139 6.9E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 SMART SM00857 5 139 3.9E-48 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 Gene3D G3DSA:1.10.10.60 127 184 6.8E-10 T 28-03-2018 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 Gene3D G3DSA:1.20.5.40 108 126 1.9E-17 T 28-03-2018 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 Gene3D G3DSA:3.40.50.1390 4 107 8.7E-33 T 28-03-2018 AFA_RS12310 20bd9b96d7a379e9bd7ac7bfee088dc9 185 SUPERFAMILY SSF46689 141 182 7.57E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02650 bea41f4ecaf8335b42c7309978d80b68 425 Pfam PF13660 Domain of unknown function (DUF4147) 9 230 9.4E-84 T 28-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 AFA_RS02650 bea41f4ecaf8335b42c7309978d80b68 425 Pfam PF05161 MOFRL family 309 414 7.8E-35 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 AFA_RS02650 bea41f4ecaf8335b42c7309978d80b68 425 Gene3D G3DSA:3.40.1480.10 244 424 2.8E-65 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 AFA_RS02650 bea41f4ecaf8335b42c7309978d80b68 425 Gene3D G3DSA:3.40.50.10180 5 243 4.5E-89 T 28-03-2018 AFA_RS02650 bea41f4ecaf8335b42c7309978d80b68 425 SUPERFAMILY SSF82544 4 420 4.45E-153 T 28-03-2018 AFA_RS10075 e3920fe837c2bc0075d789632f9f5736 308 Pfam PF01571 Aminomethyltransferase folate-binding domain 17 108 6.3E-6 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal AFA_RS10075 e3920fe837c2bc0075d789632f9f5736 308 SUPERFAMILY SSF103025 9 213 7.06E-50 T 28-03-2018 AFA_RS10075 e3920fe837c2bc0075d789632f9f5736 308 Gene3D G3DSA:3.30.70.1400 15 210 6.5E-28 T 28-03-2018 AFA_RS10075 e3920fe837c2bc0075d789632f9f5736 308 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 158 221 6.5E-27 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site AFA_RS13785 e04840ffde67320278053d63066f44d3 195 Pfam PF04355 SmpA / OmlA family 84 153 2.6E-26 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 AFA_RS13785 e04840ffde67320278053d63066f44d3 195 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 52 179 29.116 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE AFA_RS13785 e04840ffde67320278053d63066f44d3 195 Gene3D G3DSA:3.30.1450.10 84 160 8.6E-14 T 28-03-2018 AFA_RS05145 a0c48204a177c3d052bedd55abebb07a 222 Gene3D G3DSA:3.40.50.450 11 216 7.5E-65 T 28-03-2018 AFA_RS05145 a0c48204a177c3d052bedd55abebb07a 222 Pfam PF03641 Possible lysine decarboxylase 77 206 4.9E-33 T 28-03-2018 IPR031100 LOG family AFA_RS05145 a0c48204a177c3d052bedd55abebb07a 222 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 36 207 2.3E-47 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AFA_RS05145 a0c48204a177c3d052bedd55abebb07a 222 SUPERFAMILY SSF102405 14 207 1.34E-60 T 28-03-2018 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Gene3D G3DSA:2.40.30.10 2 103 5.0E-16 T 28-03-2018 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 242 313 1.1E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Gene3D G3DSA:3.40.50.80 107 224 1.5E-25 T 28-03-2018 AFA_RS00295 739e414882b2460172cf742353531ac9 322 SUPERFAMILY SSF54292 215 320 6.69E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS00295 739e414882b2460172cf742353531ac9 322 SUPERFAMILY SSF52343 100 229 2.49E-30 T 28-03-2018 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Pfam PF00970 Oxidoreductase FAD-binding domain 8 104 1.8E-4 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Pfam PF00175 Oxidoreductase NAD-binding domain 118 206 6.8E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS00295 739e414882b2460172cf742353531ac9 322 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 271 279 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS00295 739e414882b2460172cf742353531ac9 322 SUPERFAMILY SSF63380 2 102 9.85E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS00295 739e414882b2460172cf742353531ac9 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 1.7E-16 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00295 739e414882b2460172cf742353531ac9 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 136 1.7E-16 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00295 739e414882b2460172cf742353531ac9 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 1.7E-16 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00295 739e414882b2460172cf742353531ac9 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 142 151 1.7E-16 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS00295 739e414882b2460172cf742353531ac9 322 Gene3D G3DSA:3.10.20.30 225 322 4.2E-19 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS00535 5156720c6e9bfa5f7e06091a2832ddf3 386 Gene3D G3DSA:3.20.20.30 8 368 3.9E-89 T 28-03-2018 AFA_RS00535 5156720c6e9bfa5f7e06091a2832ddf3 386 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 10 384 63.225 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 AFA_RS00535 5156720c6e9bfa5f7e06091a2832ddf3 386 SUPERFAMILY SSF51679 11 362 1.83E-97 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS00535 5156720c6e9bfa5f7e06091a2832ddf3 386 Pfam PF00296 Luciferase-like monooxygenase 11 331 6.8E-86 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS00535 5156720c6e9bfa5f7e06091a2832ddf3 386 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 10 355 1.4E-175 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 PRINTS PR01486 Bacterial phospholipase A1 protein signature 293 307 3.6E-10 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 PRINTS PR01486 Bacterial phospholipase A1 protein signature 215 232 3.6E-10 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 PRINTS PR01486 Bacterial phospholipase A1 protein signature 344 362 3.6E-10 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 PRINTS PR01486 Bacterial phospholipase A1 protein signature 404 424 3.6E-10 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 SUPERFAMILY SSF56931 198 432 6.93E-49 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 Pfam PF02253 Phospholipase A1 218 431 4.3E-32 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS04290 a189498fa746f65f0cbd0d1a084b5b64 433 Gene3D G3DSA:2.40.230.10 192 433 1.6E-48 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 18 301 1.0E-118 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 Gene3D G3DSA:3.40.50.150 103 303 3.6E-34 T 28-03-2018 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 20 306 6.9E-71 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 PIRSF PIRSF037167 6 307 4.5E-123 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 11 307 49.239 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 Gene3D G3DSA:1.10.8.10 7 101 9.2E-16 T 28-03-2018 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 Pfam PF05175 Methyltransferase small domain 125 223 5.5E-17 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 SUPERFAMILY SSF53335 21 277 9.86E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS07565 574913b8e6302778763ea5ae2d911560 307 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 211 217 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 SUPERFAMILY SSF52540 238 479 3.78E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 SMART SM00989 124 186 1.5E-22 T 28-03-2018 IPR004096 4-vinyl reductase, 4VR AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Pfam PF06505 Activator of aromatic catabolism 13 113 1.5E-35 T 28-03-2018 IPR010523 Activator of aromatic catabolism AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 SUPERFAMILY SSF46689 450 564 3.09E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 SMART SM00382 257 401 9.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Pfam PF02830 V4R domain 125 186 2.9E-16 T 28-03-2018 IPR004096 4-vinyl reductase, 4VR AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Pfam PF02954 Bacterial regulatory protein, Fis family 523 562 1.9E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Gene3D G3DSA:1.10.10.60 526 562 4.4E-13 T 28-03-2018 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 12 131 3.0E-33 T 28-03-2018 IPR010523 Activator of aromatic catabolism AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Gene3D G3DSA:3.40.50.300 235 409 6.7E-28 T 28-03-2018 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 261 274 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Gene3D G3DSA:1.10.8.60 410 525 2.2E-23 T 28-03-2018 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Pfam PF00158 Sigma-54 interaction domain 238 404 6.1E-68 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 SUPERFAMILY SSF111126 26 181 7.85E-13 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 546 566 3.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 529 546 3.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS08505 c1bbeeb0e69331edd6d3929217f1725e 567 Gene3D G3DSA:3.30.1380.20 22 192 3.8E-40 T 28-03-2018 AFA_RS12720 3b6760e39abbf2568a727dac7af9c087 134 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 4.1E-33 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFA_RS12720 3b6760e39abbf2568a727dac7af9c087 134 Gene3D G3DSA:3.30.460.10 1 119 5.8E-32 T 28-03-2018 AFA_RS12720 3b6760e39abbf2568a727dac7af9c087 134 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 3.5E-24 T 28-03-2018 AFA_RS12720 3b6760e39abbf2568a727dac7af9c087 134 SUPERFAMILY SSF81301 1 109 4.58E-35 T 28-03-2018 AFA_RS12720 3b6760e39abbf2568a727dac7af9c087 134 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 22.851 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 Gene3D G3DSA:1.10.357.10 75 218 2.9E-10 T 28-03-2018 AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 Gene3D G3DSA:1.10.10.60 1 74 8.2E-18 T 28-03-2018 AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 SUPERFAMILY SSF48498 107 210 3.56E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 SUPERFAMILY SSF46689 18 80 1.41E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 6.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 6.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 Pfam PF16859 Bacterial transcriptional repressor C-terminal 105 190 3.1E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS14045 0feef796218801d9e2cfee10e4ac3253 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 5.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 SUPERFAMILY SSF51569 5 279 2.2E-66 T 28-03-2018 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 7 339 3.5E-178 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 344 221.386 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 SUPERFAMILY SSF89000 291 340 2.0E-18 T 28-03-2018 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 Pfam PF00682 HMGL-like 9 267 3.8E-77 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 Gene3D G3DSA:3.20.20.70 1 269 1.1E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 Gene3D G3DSA:1.10.8.60 279 340 2.9E-32 T 28-03-2018 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 275 339 2.0E-28 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFA_RS13950 771899ca14f67f26f02eb35ae09954ca 344 Pfam PF07836 DmpG-like communication domain 277 337 1.0E-29 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 SMART SM00346 15 102 0.0012 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 Gene3D G3DSA:3.30.450.40 88 256 1.5E-30 T 28-03-2018 IPR029016 GAF domain-like AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 SUPERFAMILY SSF55781 89 252 8.5E-33 T 28-03-2018 IPR029016 GAF domain-like AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 Gene3D G3DSA:1.10.10.10 6 84 1.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 SUPERFAMILY SSF46785 17 77 4.62E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 Pfam PF09339 IclR helix-turn-helix domain 17 66 6.9E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS04510 6780a6aa62d15f0308af78ac91a1632b 256 Pfam PF01614 Bacterial transcriptional regulator 136 251 8.9E-11 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS16120 30b467aad55c432be1b442f0d15224f3 296 SUPERFAMILY SSF103481 187 285 8.5E-12 T 28-03-2018 AFA_RS16120 30b467aad55c432be1b442f0d15224f3 296 Pfam PF00892 EamA-like transporter family 150 283 2.8E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS16120 30b467aad55c432be1b442f0d15224f3 296 Pfam PF00892 EamA-like transporter family 6 139 1.2E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS16120 30b467aad55c432be1b442f0d15224f3 296 SUPERFAMILY SSF103481 40 144 9.15E-16 T 28-03-2018 AFA_RS01705 919c2f8ff61778d5068660dfba58a4da 390 SUPERFAMILY SSF50969 19 373 4.71E-62 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFA_RS01705 919c2f8ff61778d5068660dfba58a4da 390 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 45 355 6.5E-46 T 28-03-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 AFA_RS01705 919c2f8ff61778d5068660dfba58a4da 390 Gene3D G3DSA:2.130.10.10 42 385 6.6E-49 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Gene3D G3DSA:3.40.120.10 264 370 1.7E-21 T 28-03-2018 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Gene3D G3DSA:3.40.120.10 154 263 1.3E-32 T 28-03-2018 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 SUPERFAMILY SSF53738 258 362 2.04E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 218 2.3E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 2.3E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 171 190 2.3E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 2.3E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 11 138 6.9E-35 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 SUPERFAMILY SSF53738 155 256 2.71E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 SUPERFAMILY SSF53738 11 138 7.46E-38 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 SUPERFAMILY SSF55957 367 461 8.11E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Gene3D G3DSA:3.30.310.50 371 462 1.1E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 1.8E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 451 7.0E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Gene3D G3DSA:3.40.120.10 5 149 1.4E-36 T 28-03-2018 AFA_RS02745 30a02c7dbd056412a99d7c41b9358a4c 462 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 364 2.3E-18 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS01035 543c1be3977d45012512b404ea011102 308 Gene3D G3DSA:3.30.2350.10 92 301 1.7E-45 T 28-03-2018 AFA_RS01035 543c1be3977d45012512b404ea011102 308 SUPERFAMILY SSF55120 85 302 4.32E-49 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS01035 543c1be3977d45012512b404ea011102 308 Pfam PF00849 RNA pseudouridylate synthase 100 251 1.3E-21 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS01035 543c1be3977d45012512b404ea011102 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS14100 7cfb4cb7d4f6dba565789256cd462763 663 ProSitePatterns PS01303 BCCT family of transporters signature. 313 322 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 AFA_RS14100 7cfb4cb7d4f6dba565789256cd462763 663 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 496 7.8E-165 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AFA_RS14100 7cfb4cb7d4f6dba565789256cd462763 663 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 495 9.9E-194 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 Pfam PF10415 Fumarase C C-terminus 415 467 4.2E-19 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 Gene3D G3DSA:1.10.40.30 423 472 3.6E-20 T 28-03-2018 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00145 Argininosuccinate lyase family signature 141 163 1.9E-5 T 28-03-2018 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00145 Argininosuccinate lyase family signature 324 340 1.9E-5 T 28-03-2018 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00145 Argininosuccinate lyase family signature 182 202 1.9E-5 T 28-03-2018 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00149 Fumarate lyase superfamily signature 142 160 7.8E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00149 Fumarate lyase superfamily signature 324 340 7.8E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00149 Fumarate lyase superfamily signature 278 305 7.8E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 PRINTS PR00149 Fumarate lyase superfamily signature 187 205 7.8E-30 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 Gene3D G3DSA:1.10.275.10 8 145 2.1E-52 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 SUPERFAMILY SSF48557 10 465 5.03E-144 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 Gene3D G3DSA:1.20.200.10 146 422 9.9E-76 T 28-03-2018 AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 Pfam PF00206 Lyase 21 349 4.2E-93 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal AFA_RS09140 60e5d9691d803476c4d42e1c19672df2 479 ProSitePatterns PS00163 Fumarate lyases signature. 324 333 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFA_RS01580 c9aaedc0c68b726b698ec271e17cd1d4 304 Pfam PF00487 Fatty acid desaturase 35 254 7.0E-16 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 SUPERFAMILY SSF51735 5 231 2.67E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 231 5.4E-48 T 28-03-2018 AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 Gene3D G3DSA:3.40.50.720 2 234 8.7E-49 T 28-03-2018 AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06120 c75635d5798d808177793c5856c94fcd 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 SUPERFAMILY SSF54292 5 90 1.01E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 201 364 6.6E-46 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 SMART SM01092 372 473 2.2E-36 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 372 472 6.4E-35 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Gene3D G3DSA:3.30.465.10 251 365 2.6E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 PIRSF PIRSF036557 3 486 6.1E-213 T 28-03-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Gene3D G3DSA:1.10.150.120 87 196 2.0E-34 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 SUPERFAMILY SSF55447 370 476 4.97E-37 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 6 473 1.1E-209 T 28-03-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Gene3D G3DSA:3.30.43.10 197 250 5.3E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 SUPERFAMILY SSF47741 98 211 3.66E-33 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Pfam PF01799 [2Fe-2S] binding domain 86 164 7.3E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 SUPERFAMILY SSF56176 186 364 5.09E-51 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Gene3D G3DSA:3.30.390.50 367 480 2.6E-33 T 28-03-2018 AFA_RS11460 67c24139ce30ae91e62ca53fd040b0fc 497 Gene3D G3DSA:3.10.20.30 3 86 1.5E-26 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS15070 7c98821c8eb1fb5d410ba5768c56578d 558 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 514 2.3E-118 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 SUPERFAMILY SSF63380 77 203 5.53E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Pfam PF00970 Oxidoreductase FAD-binding domain 122 201 2.0E-15 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Gene3D G3DSA:3.40.50.80 201 331 1.0E-28 T 28-03-2018 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 SUPERFAMILY SSF54292 9 96 7.34E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 153 160 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 195 204 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 235 244 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 148 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 299 307 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 229 9.0E-28 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Gene3D G3DSA:3.10.20.30 1 111 4.5E-23 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 SUPERFAMILY SSF52343 191 329 2.1E-35 T 28-03-2018 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 299 307 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 229 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 146 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 247 258 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 235 244 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 160 9.9E-11 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 87 1.8E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Pfam PF00175 Oxidoreductase NAD-binding domain 211 313 2.1E-23 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS08565 2939fd7b391820c8f6378f3715b185fe 335 Gene3D G3DSA:2.40.30.10 112 200 1.8E-21 T 28-03-2018 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SUPERFAMILY SSF52172 649 777 3.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF00989 PAS fold 270 382 2.4E-18 T 28-03-2018 IPR013767 PAS fold GO:0006355 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Gene3D G3DSA:1.10.287.130 403 466 2.1E-19 T 28-03-2018 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SUPERFAMILY SSF47226 748 886 1.3E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 517 629 6.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SUPERFAMILY SSF55874 459 632 2.23E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Gene3D G3DSA:3.30.450.20 268 402 9.9E-23 T 28-03-2018 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF00512 His Kinase A (phospho-acceptor) domain 405 470 6.5E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 384 2.2E-27 T 28-03-2018 IPR000014 PAS domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SUPERFAMILY SSF55785 280 394 3.32E-25 T 28-03-2018 IPR000014 PAS domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Gene3D G3DSA:3.30.565.10 474 635 7.6E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SMART SM00387 517 630 6.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 583 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 608 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 614 627 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 569 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Gene3D G3DSA:1.20.120.160 783 896 7.1E-10 T 28-03-2018 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Gene3D G3DSA:3.40.50.2300 636 782 4.4E-33 T 28-03-2018 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SMART SM00388 405 470 3.7E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SUPERFAMILY SSF47384 388 470 1.45E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SMART SM00448 649 765 1.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF03707 Bacterial signalling protein N terminal repeat 199 246 1.9E-8 T 28-03-2018 IPR005330 MHYT domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF03707 Bacterial signalling protein N terminal repeat 69 125 9.3E-17 T 28-03-2018 IPR005330 MHYT domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF03707 Bacterial signalling protein N terminal repeat 132 188 2.9E-15 T 28-03-2018 IPR005330 MHYT domain AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF00072 Response regulator receiver domain 651 765 2.4E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 Pfam PF01627 Hpt domain 830 887 1.7E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AFA_RS06615 06226eed61dbba8b6becbf89bd95cc02 988 SMART SM00091 269 335 1.0E-13 T 28-03-2018 IPR000014 PAS domain AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 Gene3D G3DSA:1.10.10.10 1 78 4.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 Gene3D G3DSA:3.40.1410.10 120 250 4.6E-17 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 SMART SM00866 102 239 7.7E-4 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 8.2E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 SUPERFAMILY SSF64288 65 246 1.57E-19 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 SUPERFAMILY SSF46785 10 81 2.41E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 Pfam PF07702 UTRA domain 152 238 2.8E-10 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 SMART SM00345 18 77 2.8E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 8.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00140 72036bd8da2466eec5346c9c1847a8e0 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 8.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 Gene3D G3DSA:1.20.1600.10 180 319 4.6E-6 T 28-03-2018 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 Gene3D G3DSA:1.10.287.470 112 179 9.1E-6 T 28-03-2018 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 SUPERFAMILY SSF111369 194 296 3.01E-6 T 28-03-2018 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 SUPERFAMILY SSF111369 123 158 3.01E-6 T 28-03-2018 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 Gene3D G3DSA:2.40.50.100 50 111 4.9E-13 T 28-03-2018 AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 296 2.6E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS14030 7c63ceb17ff2c2fbc013b1f4923bf84f 359 SUPERFAMILY SSF111369 44 109 9.81E-8 T 28-03-2018 AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 288 108.42 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 Gene3D G3DSA:3.40.50.1000 108 273 3.1E-22 T 28-03-2018 IPR023214 HAD-like domain AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 Gene3D G3DSA:1.10.150.240 39 107 1.5E-26 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 121 218 2.6E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 SUPERFAMILY SSF56784 22 273 3.1E-52 T 28-03-2018 IPR023214 HAD-like domain AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 21 272 2.3E-96 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 AFA_RS11365 ece1901b19e4a18abf10a5602c671172 288 Pfam PF13419 Haloacid dehalogenase-like hydrolase 24 218 1.8E-8 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16035 e5cb8d986ee471bf6a0cc3368e395620 321 SUPERFAMILY SSF48576 6 320 7.52E-98 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS16035 e5cb8d986ee471bf6a0cc3368e395620 321 Gene3D G3DSA:1.10.600.10 2 321 2.4E-99 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS16035 e5cb8d986ee471bf6a0cc3368e395620 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site AFA_RS16035 e5cb8d986ee471bf6a0cc3368e395620 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site AFA_RS16035 e5cb8d986ee471bf6a0cc3368e395620 321 Pfam PF00348 Polyprenyl synthetase 32 275 2.0E-76 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Pfam PF12848 ABC transporter 216 295 7.3E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 SUPERFAMILY SSF52540 294 518 1.58E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Gene3D G3DSA:1.20.58.410 563 638 9.6E-7 T 28-03-2018 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Gene3D G3DSA:3.40.50.300 307 562 3.4E-46 T 28-03-2018 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Gene3D G3DSA:3.40.50.300 1 285 1.3E-49 T 28-03-2018 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Pfam PF00005 ABC transporter 329 460 6.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 Pfam PF00005 ABC transporter 17 177 8.4E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 SMART SM00382 26 222 4.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 SMART SM00382 338 505 7.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS07560 9d98adcdcdae36871a34be50d14761ce 641 SUPERFAMILY SSF52540 2 233 1.28E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10695 bd02574bc6351833436d1540749e1878 321 Pfam PF07728 AAA domain (dynein-related subfamily) 63 187 4.6E-13 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFA_RS10695 bd02574bc6351833436d1540749e1878 321 SUPERFAMILY SSF52540 35 283 2.61E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10695 bd02574bc6351833436d1540749e1878 321 Gene3D G3DSA:3.40.50.300 48 212 1.7E-18 T 28-03-2018 AFA_RS10695 bd02574bc6351833436d1540749e1878 321 SMART SM00382 59 205 3.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS10695 bd02574bc6351833436d1540749e1878 321 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 7 36 1.6E-8 T 28-03-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 Gene3D G3DSA:3.30.9.10 167 282 8.6E-48 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 Gene3D G3DSA:3.30.9.10 306 387 1.2E-14 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.4E-26 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.4E-26 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.4E-26 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 1.4E-26 T 28-03-2018 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 Gene3D G3DSA:3.50.50.60 3 166 2.1E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 Pfam PF01494 FAD binding domain 2 341 9.5E-83 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 SUPERFAMILY SSF51905 1 171 2.98E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 SUPERFAMILY SSF51905 273 388 2.98E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 389 4.7E-196 T 28-03-2018 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 AFA_RS05575 218461ffa3387351b4c9364321f0bf62 389 SUPERFAMILY SSF54373 174 274 6.67E-45 T 28-03-2018 AFA_RS02250 ae2b0acdc18c8c50b0597bc06664450e 457 PIRSF PIRSF006060 4 455 1.2E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AFA_RS02250 ae2b0acdc18c8c50b0597bc06664450e 457 Pfam PF00324 Amino acid permease 23 432 3.0E-90 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 AFA_RS02250 ae2b0acdc18c8c50b0597bc06664450e 457 ProSitePatterns PS00218 Amino acid permeases signature. 47 77 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 SUPERFAMILY SSF46894 140 207 2.24E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 SUPERFAMILY SSF52172 11 159 5.27E-31 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS15580 b319539583785d56e83a3b15e2337239 213 Pfam PF00072 Response regulator receiver domain 14 124 7.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 SMART SM00421 147 204 1.9E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 Gene3D G3DSA:1.10.10.10 139 208 3.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15580 b319539583785d56e83a3b15e2337239 213 SMART SM00448 12 123 1.6E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 202 5.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS15580 b319539583785d56e83a3b15e2337239 213 Gene3D G3DSA:3.40.50.2300 2 138 6.5E-29 T 28-03-2018 AFA_RS01445 02f2645247a5e2c36bebe5f154183dad 81 SUPERFAMILY SSF47336 2 78 1.44E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS01445 02f2645247a5e2c36bebe5f154183dad 81 Gene3D G3DSA:1.10.1200.10 2 81 2.6E-11 T 28-03-2018 AFA_RS01445 02f2645247a5e2c36bebe5f154183dad 81 Pfam PF00550 Phosphopantetheine attachment site 9 68 8.3E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 244 5.5E-92 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 SUPERFAMILY SSF51735 4 246 3.66E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 Gene3D G3DSA:3.40.50.720 45 246 3.3E-71 T 28-03-2018 AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 Gene3D G3DSA:3.40.50.720 1 44 5.7E-12 T 28-03-2018 AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 1.3E-5 T 28-03-2018 AFA_RS17410 e8b564a09370073208f8f7aa0df32372 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 6.3E-74 T 28-03-2018 AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 Gene3D G3DSA:3.40.50.1240 2 212 4.9E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 SMART SM00855 4 160 2.7E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 SUPERFAMILY SSF53254 2 207 5.96E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 199 1.1E-51 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFA_RS04145 0823028017769fd240e48e2e9f5058af 212 PIRSF PIRSF000709 2 132 1.2E-8 T 28-03-2018 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 SUPERFAMILY SSF51395 8 343 1.53E-102 T 28-03-2018 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 Pfam PF01180 Dihydroorotate dehydrogenase 53 343 9.0E-89 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 PIRSF PIRSF000164 15 344 8.4E-97 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 7 344 49.421 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 342 1.0E-127 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFA_RS14345 1f2665a2a8e6ea0c7254308aa99b3c56 344 Gene3D G3DSA:3.20.20.70 2 344 9.3E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 Pfam PF11867 Domain of unknown function (DUF3387) 761 1009 2.7E-10 T 28-03-2018 IPR021810 Protein of unknown function DUF3387 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 Gene3D G3DSA:3.40.50.300 315 496 1.2E-19 T 28-03-2018 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 SUPERFAMILY SSF52540 564 709 8.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 SUPERFAMILY SSF52540 450 518 8.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 216 1.7E-36 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 SMART SM00487 314 510 4.5E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 SUPERFAMILY SSF52540 281 489 3.42E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 Gene3D G3DSA:3.40.50.300 563 710 6.8E-6 T 28-03-2018 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 Pfam PF04851 Type III restriction enzyme, res subunit 318 483 1.7E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFA_RS02165 74713a867678c03d365a685f29be25e6 1036 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 8 726 2.3E-160 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 50 683 1.6E-250 T 28-03-2018 IPR010100 TonB-dependent copper receptor AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 Gene3D G3DSA:2.170.130.10 23 157 2.4E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 Pfam PF00593 TonB dependent receptor 205 680 4.1E-47 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 147 4.8E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 Gene3D G3DSA:2.40.170.20 158 683 1.9E-62 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS17585 44f62c28c8ee53ff8c9831e729ca9a3e 683 SUPERFAMILY SSF56935 21 683 1.83E-90 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 Gene3D G3DSA:3.30.870.10 315 472 1.1E-29 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 Pfam PF13091 PLD-like domain 336 453 1.5E-26 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 Pfam PF13091 PLD-like domain 141 284 1.1E-16 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 SUPERFAMILY SSF56024 111 321 2.0E-48 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 Gene3D G3DSA:3.30.870.10 109 295 2.3E-34 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 SUPERFAMILY SSF56024 276 470 6.5E-44 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 SMART SM00155 224 251 5.0 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 SMART SM00155 402 429 1.3E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 Pfam PF13396 Phospholipase_D-nuclease N-terminal 31 67 1.6E-5 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 PIRSF PIRSF000850 373 464 7.1E-4 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 PIRSF PIRSF000850 116 199 0.02 T 28-03-2018 AFA_RS04315 67d655c4a7edafb6d2a64d14714768b5 489 PIRSF PIRSF000850 320 377 0.26 T 28-03-2018 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Gene3D G3DSA:3.40.50.720 242 368 1.2E-9 T 28-03-2018 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Pfam PF01266 FAD dependent oxidoreductase 253 600 1.8E-33 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 SUPERFAMILY SSF51905 253 466 7.25E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 SUPERFAMILY SSF51905 563 609 7.25E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 254 573 7.7E-55 T 28-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Gene3D G3DSA:3.30.9.10 416 562 1.2E-18 T 28-03-2018 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 10 621 20.242 T 28-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Gene3D G3DSA:3.40.50.150 13 241 1.5E-70 T 28-03-2018 AFA_RS03745 24e431c2b80ed1f61687596f14cf5bfc 621 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 116 235 5.1E-32 T 28-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 SUPERFAMILY SSF56003 138 769 2.49E-201 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 701 7.5E-197 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Gene3D G3DSA:3.30.365.10 612 773 3.0E-60 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 SMART SM01008 31 138 4.4E-48 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Gene3D G3DSA:3.30.365.10 160 268 6.3E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Gene3D G3DSA:3.30.365.10 269 431 8.2E-50 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Gene3D G3DSA:3.30.365.10 451 611 1.8E-48 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Gene3D G3DSA:3.90.1170.50 15 138 3.3E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS11465 367d8f6afef8da7544ea079855619498 775 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 18 772 0.0 T 28-03-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 AFA_RS11465 367d8f6afef8da7544ea079855619498 775 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 31 138 3.4E-27 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS11465 367d8f6afef8da7544ea079855619498 775 SUPERFAMILY SSF54665 11 139 1.05E-39 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15725 2f449a9b5967ba9b7fb6dc1cbe1d15e7 269 SUPERFAMILY SSF53613 12 263 6.54E-28 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15725 2f449a9b5967ba9b7fb6dc1cbe1d15e7 269 Pfam PF08543 Phosphomethylpyrimidine kinase 20 259 3.4E-22 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFA_RS15725 2f449a9b5967ba9b7fb6dc1cbe1d15e7 269 Gene3D G3DSA:3.40.1190.20 12 196 4.5E-18 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15725 2f449a9b5967ba9b7fb6dc1cbe1d15e7 269 Gene3D G3DSA:3.40.1190.20 216 268 0.063 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 SUPERFAMILY SSF51735 150 319 7.07E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 Gene3D G3DSA:3.90.180.10 1 171 6.6E-45 T 28-03-2018 AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 SUPERFAMILY SSF50129 1 166 3.14E-48 T 28-03-2018 IPR011032 GroES-like AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 SMART SM00829 8 354 2.3E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 144 2.0E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 Gene3D G3DSA:3.40.50.10730 172 310 2.9E-31 T 28-03-2018 AFA_RS00205 67205f7d1554ce827f6d21b5146daa19 357 Pfam PF00107 Zinc-binding dehydrogenase 188 299 5.3E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 Pfam PF01047 MarR family 51 110 2.5E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 SMART SM00347 44 145 2.7E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 Gene3D G3DSA:1.10.10.10 8 155 3.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 1.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 1.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 1.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12060 6fbdf702b92011f56782d970a4b7d28c 162 SUPERFAMILY SSF46785 19 156 2.05E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04135 f8ddff9e110db372a1cb5266718ea8ce 298 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 70 222 8.6E-47 T 28-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 AFA_RS04135 f8ddff9e110db372a1cb5266718ea8ce 298 Gene3D G3DSA:2.60.120.330 60 237 2.5E-45 T 28-03-2018 IPR027443 Isopenicillin N synthase-like AFA_RS04135 f8ddff9e110db372a1cb5266718ea8ce 298 SUPERFAMILY SSF51197 93 222 2.25E-20 T 28-03-2018 AFA_RS12000 25c954f9e7f2701e21975ee841818700 240 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 13 239 38.714 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AFA_RS12000 25c954f9e7f2701e21975ee841818700 240 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 15 233 3.7E-85 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AFA_RS12000 25c954f9e7f2701e21975ee841818700 240 Gene3D G3DSA:3.40.50.150 2 239 7.0E-50 T 28-03-2018 AFA_RS12000 25c954f9e7f2701e21975ee841818700 240 SUPERFAMILY SSF53335 17 220 1.55E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12000 25c954f9e7f2701e21975ee841818700 240 Pfam PF13489 Methyltransferase domain 55 206 3.0E-23 T 28-03-2018 AFA_RS08770 bbfc498047ddedbe070aa88cb5df71b8 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 473 1.6E-196 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 AFA_RS08770 bbfc498047ddedbe070aa88cb5df71b8 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 453 1.4E-67 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFA_RS08770 bbfc498047ddedbe070aa88cb5df71b8 482 SUPERFAMILY SSF101960 36 81 1.22E-139 T 28-03-2018 AFA_RS08770 bbfc498047ddedbe070aa88cb5df71b8 482 SUPERFAMILY SSF101960 108 479 1.22E-139 T 28-03-2018 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 SMART SM00422 11 79 1.0E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 SUPERFAMILY SSF46955 11 133 2.64E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 Gene3D G3DSA:1.10.1660.10 7 65 2.8E-18 T 28-03-2018 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 Pfam PF00376 MerR family regulatory protein 12 48 1.2E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 Pfam PF09278 MerR, DNA binding 54 118 2.8E-16 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 Gene3D G3DSA:1.10.1660.10 66 137 9.6E-12 T 28-03-2018 AFA_RS14105 3c04598f17eb0aa154a120e8ba7569e0 158 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 11 150 1.6E-62 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 AFA_RS14855 9350f06f27a72d677ea51d1b2bb95456 173 SUPERFAMILY SSF101307 20 168 1.31E-34 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFA_RS14855 9350f06f27a72d677ea51d1b2bb95456 173 Gene3D G3DSA:1.10.3760.10 57 169 3.9E-34 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFA_RS14855 9350f06f27a72d677ea51d1b2bb95456 173 PIRSF PIRSF006162 15 172 1.1E-37 T 28-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFA_RS14855 9350f06f27a72d677ea51d1b2bb95456 173 Pfam PF04608 Phosphatidylglycerophosphatase A 26 166 1.1E-44 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 Gene3D G3DSA:3.40.50.300 1 258 1.6E-72 T 28-03-2018 AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 SMART SM00382 28 228 6.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 SUPERFAMILY SSF52540 6 250 2.25E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 Pfam PF00005 ABC transporter 19 180 2.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 PIRSF PIRSF039085 1 254 4.8E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS00395 92cb53de8d7659ffd6afeed97e455e83 259 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 Pfam PF00301 Rubredoxin 4 49 2.5E-22 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 SUPERFAMILY SSF57802 1 53 4.04E-23 T 28-03-2018 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 PRINTS PR00163 Rubredoxin signature 33 49 3.8E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 PRINTS PR00163 Rubredoxin signature 3 19 3.8E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 Gene3D G3DSA:2.20.28.10 1 53 5.1E-26 T 28-03-2018 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AFA_RS15720 f3458c68d846ef6338715aeafae85319 54 PIRSF PIRSF000071 1 54 5.9E-26 T 28-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 AFA_RS09505 e98aa72d58d33b1f160e3929037353b8 399 Gene3D G3DSA:1.10.150.130 41 181 3.7E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS09505 e98aa72d58d33b1f160e3929037353b8 399 Pfam PF00589 Phage integrase family 202 383 9.9E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS09505 e98aa72d58d33b1f160e3929037353b8 399 Gene3D G3DSA:1.10.443.10 182 385 2.3E-31 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS09505 e98aa72d58d33b1f160e3929037353b8 399 SUPERFAMILY SSF56349 129 391 2.85E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS09505 e98aa72d58d33b1f160e3929037353b8 399 SUPERFAMILY SSF56349 48 102 2.85E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS05050 5dfb0ebf37fa3340976ab29b81b34b43 839 SUPERFAMILY SSF53955 389 512 2.25E-23 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS05050 5dfb0ebf37fa3340976ab29b81b34b43 839 Gene3D G3DSA:1.10.530.10 348 514 6.4E-26 T 28-03-2018 AFA_RS05050 5dfb0ebf37fa3340976ab29b81b34b43 839 Pfam PF01464 Transglycosylase SLT domain 395 501 8.4E-14 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS05465 2da44fa6712beac2f3f240d8c995d3e8 401 Pfam PF01266 FAD dependent oxidoreductase 1 354 6.1E-41 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS05465 2da44fa6712beac2f3f240d8c995d3e8 401 Gene3D G3DSA:3.50.50.60 1 376 3.1E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05465 2da44fa6712beac2f3f240d8c995d3e8 401 SUPERFAMILY SSF51905 1 219 9.5E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05465 2da44fa6712beac2f3f240d8c995d3e8 401 SUPERFAMILY SSF51905 317 363 9.5E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05990 8f4bb59379274c1732b3b93f1bc97316 462 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 105 2.7E-15 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 AFA_RS05990 8f4bb59379274c1732b3b93f1bc97316 462 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 222 442 1.9E-49 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 SUPERFAMILY SSF53795 132 297 3.05E-34 T 28-03-2018 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 Pfam PF02603 HPr Serine kinase N terminus 3 127 7.0E-22 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 Gene3D G3DSA:3.40.50.300 132 289 2.4E-41 T 28-03-2018 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 Gene3D G3DSA:3.40.1390.20 2 129 1.3E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 Pfam PF07475 HPr Serine kinase C-terminal domain 130 297 1.9E-62 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 299 1.5E-95 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 SUPERFAMILY SSF75138 2 131 1.57E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like AFA_RS16360 8be52a670afcfd2fac01633a4f67996f 308 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 305 36.864 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 193 9.4E-53 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 Gene3D G3DSA:3.30.1220.10 249 364 6.0E-32 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 SUPERFAMILY SSF52540 12 216 2.94E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 Gene3D G3DSA:3.40.50.300 8 212 2.3E-46 T 28-03-2018 AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 269 363 1.4E-23 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 SMART SM00833 269 363 4.0E-20 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS01970 35ed5d33261d6cb2971a8ab625c6d8e2 364 SUPERFAMILY SSF90002 269 363 1.57E-26 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 SMART SM00829 11 322 5.6E-35 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 SUPERFAMILY SSF51735 112 271 3.77E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 Gene3D G3DSA:3.40.50.720 134 308 5.5E-35 T 28-03-2018 AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 86 3.3E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 Gene3D G3DSA:3.90.180.10 1 133 3.7E-40 T 28-03-2018 AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 SUPERFAMILY SSF50129 2 144 6.45E-40 T 28-03-2018 IPR011032 GroES-like AFA_RS12675 35f67108c8eb21243a974644ff9b42e8 325 Pfam PF00107 Zinc-binding dehydrogenase 151 280 3.9E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS03970 3a92f0dcd0321efae427b434bd5dbe6b 331 Gene3D G3DSA:3.40.190.10 159 305 1.6E-12 T 28-03-2018 AFA_RS03970 3a92f0dcd0321efae427b434bd5dbe6b 331 SUPERFAMILY SSF53850 118 295 1.52E-9 T 28-03-2018 AFA_RS03970 3a92f0dcd0321efae427b434bd5dbe6b 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 5.7E-82 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS03970 3a92f0dcd0321efae427b434bd5dbe6b 331 PIRSF PIRSF017082 3 330 2.4E-84 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS07410 6c6876ebbc0d02760073737372beef21 107 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 99 1.0E-35 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 AFA_RS07410 6c6876ebbc0d02760073737372beef21 107 SUPERFAMILY SSF54736 20 103 1.46E-31 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFA_RS07410 6c6876ebbc0d02760073737372beef21 107 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 10 99 27.644 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS AFA_RS07410 6c6876ebbc0d02760073737372beef21 107 Gene3D G3DSA:3.30.1390.10 11 103 6.2E-35 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Gene3D G3DSA:3.30.460.10 13 157 1.5E-19 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 17 847 4.4E-221 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 SUPERFAMILY SSF55021 782 834 6.49E-8 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 SUPERFAMILY SSF81301 23 151 3.27E-16 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Pfam PF08335 GlnD PII-uridylyltransferase 160 297 4.1E-28 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Gene3D G3DSA:1.10.3090.10 291 613 3.7E-40 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Pfam PF01966 HD domain 435 564 3.0E-9 T 28-03-2018 IPR006674 HD domain AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Pfam PF01909 Nucleotidyltransferase domain 43 88 3.1E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 SUPERFAMILY SSF109604 401 524 1.13E-13 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Gene3D G3DSA:3.30.70.260 670 746 2.4E-4 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 PIRSF PIRSF006288 1 859 2.0E-280 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 859 275.368 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Gene3D G3DSA:1.20.120.330 158 290 3.4E-18 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 SUPERFAMILY SSF55021 670 726 7.91E-6 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 Gene3D G3DSA:3.30.70.260 780 859 7.7E-11 T 28-03-2018 AFA_RS10220 0e2c5fa8180c6a299001e7f518216c81 859 SMART SM00471 431 578 3.7E-7 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 Pfam PF02803 Thiolase, C-terminal domain 252 349 1.8E-11 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 Gene3D G3DSA:3.40.47.10 215 373 1.8E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 SUPERFAMILY SSF53901 232 364 1.19E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 ProSitePatterns PS00737 Thiolases signature 2. 313 329 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 Pfam PF00108 Thiolase, N-terminal domain 5 213 4.8E-17 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 SUPERFAMILY SSF53901 3 219 2.31E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 Gene3D G3DSA:3.40.47.10 1 214 4.1E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10370 2891123a97c071d90d9b8f69f5b2a22b 381 PIRSF PIRSF000429 2 367 1.5E-56 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 3.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 3.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 3.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 SUPERFAMILY SSF46894 134 200 6.8E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 Gene3D G3DSA:1.10.10.10 144 201 5.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 197 2.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 SMART SM00421 143 200 2.9E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS18070 c6f3fac34f189d546b9a4096dc5cb429 204 Gene3D G3DSA:3.40.50.2300 13 137 2.7E-4 T 28-03-2018 AFA_RS02385 7f9a35a212e13db48a2bd8bc73a8d276 294 SUPERFAMILY SSF103481 212 291 1.57E-8 T 28-03-2018 AFA_RS02385 7f9a35a212e13db48a2bd8bc73a8d276 294 SUPERFAMILY SSF103481 38 142 1.03E-12 T 28-03-2018 AFA_RS02385 7f9a35a212e13db48a2bd8bc73a8d276 294 Pfam PF00892 EamA-like transporter family 5 138 2.8E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS02450 91fe21d1b6cf1f62c08f1a27c7d9f087 255 Gene3D G3DSA:3.40.50.150 35 249 2.2E-27 T 28-03-2018 AFA_RS02450 91fe21d1b6cf1f62c08f1a27c7d9f087 255 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 29 241 31.178 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFA_RS02450 91fe21d1b6cf1f62c08f1a27c7d9f087 255 SUPERFAMILY SSF53335 23 240 4.53E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02450 91fe21d1b6cf1f62c08f1a27c7d9f087 255 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 59 240 7.6E-58 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFA_RS02450 91fe21d1b6cf1f62c08f1a27c7d9f087 255 Pfam PF02390 Putative methyltransferase 69 236 6.4E-57 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 2.2E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 6.7E-78 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 SUPERFAMILY SSF64005 12 238 6.28E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 39.513 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFA_RS10190 7d8fcad2913c51a383d585d1ca9b89d0 254 Gene3D G3DSA:3.40.1180.10 1 246 1.9E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFA_RS11840 b0d44239cd5e785e8ed3c8f38614749b 166 SUPERFAMILY SSF117916 4 100 5.01E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain AFA_RS11840 b0d44239cd5e785e8ed3c8f38614749b 166 Gene3D G3DSA:2.20.25.10 125 161 4.6E-4 T 28-03-2018 AFA_RS11840 b0d44239cd5e785e8ed3c8f38614749b 166 Pfam PF01883 Iron-sulfur cluster assembly protein 8 78 4.3E-15 T 28-03-2018 IPR002744 MIP18 family-like AFA_RS11840 b0d44239cd5e785e8ed3c8f38614749b 166 Gene3D G3DSA:3.30.300.130 3 101 4.8E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain AFA_RS11840 b0d44239cd5e785e8ed3c8f38614749b 166 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 17 165 1.2E-60 T 28-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit AFA_RS08640 4eaa234ddfc307e217a787e92ee93532 123 Pfam PF14903 WG containing repeat 67 87 0.019 T 28-03-2018 IPR032774 WG containing repeat AFA_RS08640 4eaa234ddfc307e217a787e92ee93532 123 Pfam PF14903 WG containing repeat 25 58 0.027 T 28-03-2018 IPR032774 WG containing repeat AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Pfam PF00809 Pterin binding enzyme 371 609 1.7E-56 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Gene3D G3DSA:3.40.50.280 773 928 2.9E-53 T 28-03-2018 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Pfam PF02310 B12 binding domain 778 872 3.0E-16 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 PIRSF PIRSF000381 13 1229 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SUPERFAMILY SSF56507 934 1256 3.14E-118 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Pfam PF02607 B12 binding domain 678 755 4.5E-24 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Gene3D G3DSA:1.10.1240.10 666 763 5.1E-36 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 TIGRFAM TIGR02082 metH: methionine synthase 25 1226 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Gene3D G3DSA:3.20.20.20 356 665 2.1E-71 T 28-03-2018 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SUPERFAMILY SSF82282 19 410 6.41E-114 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Gene3D G3DSA:3.20.20.330 13 348 5.1E-108 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SMART SM01018 676 763 4.1E-40 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Gene3D G3DSA:3.10.196.10 989 1257 1.6E-90 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SUPERFAMILY SSF47644 671 762 1.07E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 970 1241 2.2E-114 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SUPERFAMILY SSF52242 772 927 1.16E-41 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 SUPERFAMILY SSF51717 367 635 1.3E-85 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS16135 ddb59f79eec1533ecfddab378586de20 1257 Pfam PF02574 Homocysteine S-methyltransferase 28 334 5.7E-79 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFA_RS16180 0251249fe973d77913f39dfddffb9d53 231 Pfam PF01048 Phosphorylase superfamily 4 228 3.8E-55 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFA_RS16180 0251249fe973d77913f39dfddffb9d53 231 SUPERFAMILY SSF53167 4 228 3.01E-65 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFA_RS16180 0251249fe973d77913f39dfddffb9d53 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 4 228 2.7E-48 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFA_RS16180 0251249fe973d77913f39dfddffb9d53 231 Gene3D G3DSA:3.40.50.1580 1 231 1.8E-56 T 28-03-2018 AFA_RS07470 6cce0bd1a3f455071dab35eb707f71a5 140 SUPERFAMILY SSF51735 22 140 1.34E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07470 6cce0bd1a3f455071dab35eb707f71a5 140 Gene3D G3DSA:3.40.50.720 10 140 3.3E-28 T 28-03-2018 AFA_RS07470 6cce0bd1a3f455071dab35eb707f71a5 140 Pfam PF00106 short chain dehydrogenase 28 140 1.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07470 6cce0bd1a3f455071dab35eb707f71a5 140 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 4.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07470 6cce0bd1a3f455071dab35eb707f71a5 140 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 4.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 SUPERFAMILY SSF90123 23 336 8.89E-65 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 Pfam PF00005 ABC transporter 370 518 5.2E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 SUPERFAMILY SSF52540 344 588 5.53E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 Pfam PF00664 ABC transporter transmembrane region 35 307 1.2E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 Gene3D G3DSA:1.20.1560.10 15 340 1.1E-57 T 28-03-2018 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 Gene3D G3DSA:3.40.50.300 341 593 3.2E-80 T 28-03-2018 AFA_RS08760 faad116c2aab1eb9a99cda2e4fbd83e7 593 SMART SM00382 378 570 8.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01415 98a20293f98d614f62576934f7e90026 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 Gene3D G3DSA:3.40.50.720 1 258 4.4E-66 T 28-03-2018 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 256 1.5E-55 T 28-03-2018 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 258 6.1E-103 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 209 228 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 85 102 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 105 125 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 170 193 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 235 254 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 9.9E-54 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 AFA_RS01415 98a20293f98d614f62576934f7e90026 260 SUPERFAMILY SSF51735 5 257 1.59E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS01415 98a20293f98d614f62576934f7e90026 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 186 0.005 T 28-03-2018 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Pfam PF07724 AAA domain (Cdc48 subfamily) 187 331 6.9E-38 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 445 5.0E-198 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 445 42.201 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Gene3D G3DSA:1.10.8.10 118 200 2.4E-27 T 28-03-2018 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 SMART SM00382 51 334 4.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Gene3D G3DSA:1.10.8.10 201 243 1.4E-13 T 28-03-2018 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Gene3D G3DSA:3.40.50.300 51 117 0.0021 T 28-03-2018 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 101 2.1E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 Gene3D G3DSA:1.10.8.60 337 433 5.6E-25 T 28-03-2018 AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 SMART SM01086 337 433 1.9E-15 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS01950 4e530bf224183a8de534633ea4617d66 445 SUPERFAMILY SSF52540 5 440 2.22E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 PRINTS PR00811 Bacterial general secretion pathway protein D signature 388 402 4.5E-14 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 PRINTS PR00811 Bacterial general secretion pathway protein D signature 235 259 4.5E-14 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 PRINTS PR00811 Bacterial general secretion pathway protein D signature 179 189 4.5E-14 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 PRINTS PR00811 Bacterial general secretion pathway protein D signature 365 383 4.5E-14 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 PRINTS PR00811 Bacterial general secretion pathway protein D signature 272 282 4.5E-14 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 Pfam PF00263 Bacterial type II and III secretion system protein 239 401 2.2E-43 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 AFA_RS13680 fe517fb9524a88e8bd8afd3aedbe6acc 444 Pfam PF13629 Pilus formation protein N terminal region 40 114 1.1E-15 T 28-03-2018 IPR032789 Pilus formation protein, N-terminal AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 SUPERFAMILY SSF55073 299 454 1.41E-43 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 SMART SM00267 282 455 3.6E-51 T 28-03-2018 IPR000160 GGDEF domain AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 Pfam PF11563 Protoglobin 29 163 2.7E-14 T 28-03-2018 AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 Gene3D G3DSA:1.10.490.10 22 164 5.9E-20 T 28-03-2018 AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 293 454 2.9E-46 T 28-03-2018 IPR000160 GGDEF domain AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 Gene3D G3DSA:3.30.70.270 286 455 6.6E-49 T 28-03-2018 AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 SUPERFAMILY SSF46458 30 155 5.68E-19 T 28-03-2018 IPR009050 Globin-like AFA_RS18435 bf7eda8d4c58935dbe9a6220eca30f2a 455 Pfam PF00990 Diguanylate cyclase, GGDEF domain 296 451 1.6E-40 T 28-03-2018 IPR000160 GGDEF domain AFA_RS13725 a9d3214acd6b2c5cc9898cc9cb2847e3 688 Gene3D G3DSA:1.20.120.20 302 502 0.0012 T 28-03-2018 AFA_RS13725 a9d3214acd6b2c5cc9898cc9cb2847e3 688 Gene3D G3DSA:1.20.120.20 151 294 0.0023 T 28-03-2018 AFA_RS13725 a9d3214acd6b2c5cc9898cc9cb2847e3 688 Pfam PF15984 Bacterial collagen, middle region 279 419 4.6E-12 T 28-03-2018 IPR031929 Bacterial collagen-like protein, middle domain AFA_RS13725 a9d3214acd6b2c5cc9898cc9cb2847e3 688 Pfam PF15984 Bacterial collagen, middle region 157 260 7.1E-14 T 28-03-2018 IPR031929 Bacterial collagen-like protein, middle domain AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 214 1.8E-86 T 28-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 Gene3D G3DSA:1.20.1050.10 99 215 3.8E-23 T 28-03-2018 AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 SUPERFAMILY SSF47616 82 213 1.32E-28 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 76 5.3E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 Gene3D G3DSA:3.40.30.10 1 98 3.7E-28 T 28-03-2018 AFA_RS12765 99ce80fa5b6f200033b810a4c1bc7d51 215 SUPERFAMILY SSF52833 1 86 7.18E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12880 d47289d29e2e799a37e19418ea8b5b2b 101 Pfam PF04977 Septum formation initiator 13 89 4.5E-23 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 AFA_RS12880 d47289d29e2e799a37e19418ea8b5b2b 101 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 31.191 T 28-03-2018 IPR023081 Cell division protein FtsB AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 212 335 1.6E-34 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Gene3D G3DSA:3.30.465.10 72 224 2.3E-49 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Gene3D G3DSA:3.90.78.10 227 336 1.8E-38 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 336 80.589 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 SUPERFAMILY SSF56176 8 195 1.42E-36 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 SUPERFAMILY SSF56194 208 336 1.7E-47 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Pfam PF01565 FAD binding domain 35 153 5.5E-17 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 Gene3D G3DSA:3.30.43.10 1 71 8.4E-16 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS13800 2e0c5671d3668852033314f9d1ea7f6d 336 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 332 1.5E-68 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 SMART SM00487 24 227 2.7E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 Gene3D G3DSA:3.40.50.300 2 230 4.9E-60 T 28-03-2018 AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 Gene3D G3DSA:3.40.50.300 231 490 3.5E-46 T 28-03-2018 AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 SMART SM00490 263 344 4.4E-31 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 Pfam PF00271 Helicase conserved C-terminal domain 239 344 1.5E-25 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 SUPERFAMILY SSF52540 79 365 5.95E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFA_RS00840 6aace43dedc71e53c337a5d7dbae4f58 491 Pfam PF00270 DEAD/DEAH box helicase 29 200 2.6E-48 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 SMART SM00304 241 293 5.4E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Gene3D G3DSA:1.20.120.30 27 215 2.6E-28 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Pfam PF00672 HAMP domain 241 289 3.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Pfam PF02203 Tar ligand binding domain homologue 7 201 5.5E-16 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 SMART SM00283 294 541 3.6E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 469 498 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 421 450 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 65 80 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 419 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 10 35 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 315 344 1.5E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 353 508 9.3E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Gene3D G3DSA:1.10.287.1060 269 353 0.0011 T 28-03-2018 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 Gene3D G3DSA:1.10.287.950 354 545 2.7E-48 T 28-03-2018 AFA_RS05755 c31b22bd54fba7701a343f0283251e37 578 SUPERFAMILY SSF58104 261 546 1.16E-75 T 28-03-2018 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 Pfam PF14559 Tetratricopeptide repeat 360 426 7.8E-12 T 28-03-2018 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 Gene3D G3DSA:3.30.2010.10 61 151 1.3E-19 T 28-03-2018 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 Pfam PF01435 Peptidase family M48 73 261 5.2E-32 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 Gene3D G3DSA:1.25.40.10 152 345 5.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 Gene3D G3DSA:1.25.40.10 346 490 6.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14400 47c5e7dc02ea5a2843f6dd813ef5c4bc 497 SUPERFAMILY SSF48452 271 464 9.48E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 3.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 3.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 SMART SM00418 18 96 8.9E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 SUPERFAMILY SSF46785 15 100 1.55E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 Pfam PF01022 Bacterial regulatory protein, arsR family 25 70 1.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS05665 f3ed53df1109e45bcccc59046bcfca42 108 Gene3D G3DSA:1.10.10.10 1 94 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13570 d0c38b700241c9f16c3145ea42ccbdaa 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS13570 d0c38b700241c9f16c3145ea42ccbdaa 430 Gene3D G3DSA:1.20.1250.20 218 430 3.3E-21 T 28-03-2018 AFA_RS13570 d0c38b700241c9f16c3145ea42ccbdaa 430 Pfam PF07690 Major Facilitator Superfamily 19 385 2.9E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS13570 d0c38b700241c9f16c3145ea42ccbdaa 430 SUPERFAMILY SSF103473 5 426 8.76E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13570 d0c38b700241c9f16c3145ea42ccbdaa 430 Gene3D G3DSA:1.20.1250.20 1 217 2.3E-28 T 28-03-2018 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 SUPERFAMILY SSF52833 2 103 2.38E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 Gene3D G3DSA:3.40.30.10 1 126 8.3E-36 T 28-03-2018 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.3E-29 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 Pfam PF00085 Thioredoxin 3 101 1.7E-26 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 PRINTS PR00421 Thioredoxin family signature 29 38 1.8E-8 T 28-03-2018 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 PRINTS PR00421 Thioredoxin family signature 21 29 1.8E-8 T 28-03-2018 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 PRINTS PR00421 Thioredoxin family signature 68 79 1.8E-8 T 28-03-2018 AFA_RS10610 8f4e8d204c66f447658d5e5cb6ecdf2c 126 PIRSF PIRSF000077 1 104 8.5E-28 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFA_RS12595 471863b3683937e3e142493b1745f257 230 SUPERFAMILY SSF161098 21 208 3.01E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12595 471863b3683937e3e142493b1745f257 230 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 6 222 3.7E-85 T 28-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD AFA_RS12595 471863b3683937e3e142493b1745f257 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 222 4.6E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12595 471863b3683937e3e142493b1745f257 230 Gene3D G3DSA:1.10.3720.10 3 226 2.7E-35 T 28-03-2018 AFA_RS12595 471863b3683937e3e142493b1745f257 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 117 3.7E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SMART SM00487 610 800 5.1E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SMART SM00982 1018 1118 4.5E-41 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Gene3D G3DSA:3.40.50.300 431 791 4.6E-39 T 28-03-2018 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF52540 33 351 1.14E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1091 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Gene3D G3DSA:3.40.50.300 798 966 3.9E-25 T 28-03-2018 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF52540 360 473 2.34E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Pfam PF03461 TRCF domain 1019 1110 1.9E-24 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Pfam PF02559 CarD-like/TRCF domain 490 585 9.9E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Pfam PF00271 Helicase conserved C-terminal domain 815 919 7.2E-17 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF143517 1004 1156 1.14E-36 T 28-03-2018 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SMART SM00490 836 920 1.8E-17 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 41 1117 27.915 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF52540 793 1000 1.19E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Gene3D G3DSA:3.30.2060.10 140 185 0.002 T 28-03-2018 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SMART SM01058 489 586 4.9E-43 T 28-03-2018 IPR003711 CarD-like/TRCF domain AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF52540 533 793 7.12E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 Pfam PF00270 DEAD/DEAH box helicase 615 772 7.0E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS13330 484ddbd867f29af2b603ed4b4ef312a1 1159 SUPERFAMILY SSF141259 481 558 4.84E-22 T 28-03-2018 IPR003711 CarD-like/TRCF domain AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:3.40.50.300 35 137 0.0011 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:3.40.50.300 656 986 1.4E-53 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 SUPERFAMILY SSF52540 660 958 4.11E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 465 970 1.2E-262 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:3.40.50.300 2 34 0.049 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 SUPERFAMILY SSF52540 1 204 2.07E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 SUPERFAMILY SSF52540 476 615 2.07E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:3.40.50.300 466 655 6.9E-23 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 985 21.885 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:1.10.8.280 285 403 3.6E-33 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 Gene3D G3DSA:3.30.190.20 138 246 9.4E-36 T 28-03-2018 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 ProSitePatterns PS00211 ABC transporters family signature. 533 547 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS17875 0ddab3ca828c8736695582ebbd491a4a 987 ProSitePatterns PS00211 ABC transporters family signature. 875 889 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS17645 17535e716d7f4f0ce8d2d2927495653a 201 Pfam PF05962 HutD 17 186 3.1E-51 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves AFA_RS17645 17535e716d7f4f0ce8d2d2927495653a 201 SUPERFAMILY SSF51182 12 186 3.47E-47 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS17645 17535e716d7f4f0ce8d2d2927495653a 201 Gene3D G3DSA:2.60.120.10 15 116 2.4E-37 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS17645 17535e716d7f4f0ce8d2d2927495653a 201 Gene3D G3DSA:2.60.120.10 117 195 2.3E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 Gene3D G3DSA:3.40.50.300 76 285 2.4E-47 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 365 455 6.4E-5 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 TIGRFAM TIGR00416 sms: DNA repair protein RadA 10 455 7.9E-193 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 SUPERFAMILY SSF54211 307 460 5.31E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 SUPERFAMILY SSF54211 259 273 5.31E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 SUPERFAMILY SSF52540 73 293 1.8E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 SMART SM00382 95 248 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 Gene3D G3DSA:3.30.230.10 286 458 7.5E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 Pfam PF13481 AAA domain 89 226 9.5E-17 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 Hamap MF_01498 DNA repair protein RadA [radA]. 28 459 43.994 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 178 202 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 128 145 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 326 349 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 87 115 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 217 245 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 252 278 5.9E-94 T 28-03-2018 AFA_RS05295 5976e8bce2918fbc60f49717a154bf1e 461 PRINTS PR01874 DNA repair protein radA signature 17 41 5.9E-94 T 28-03-2018 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Pfam PF00448 SRP54-type protein, GTPase domain 285 488 4.5E-66 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 213 488 56.519 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 SMART SM00963 194 270 1.3E-19 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Pfam PF02881 SRP54-type protein, helical bundle domain 203 266 1.1E-12 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Gene3D G3DSA:1.20.120.140 394 491 6.9E-23 T 28-03-2018 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Gene3D G3DSA:3.40.50.300 271 393 1.0E-7 T 28-03-2018 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 SUPERFAMILY SSF52540 279 489 3.49E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 Gene3D G3DSA:1.20.120.140 2 270 5.4E-21 T 28-03-2018 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 SMART SM00962 284 488 3.7E-103 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 213 487 2.5E-95 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 SUPERFAMILY SSF47364 189 263 7.85E-19 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS14890 242495ae7034d9c4aba7dea96d37ebe8 491 SMART SM00382 283 461 4.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 TIGRFAM TIGR04051 rSAM_NirJ: heme d1 biosynthesis radical SAM protein NirJ 23 375 5.1E-174 T 28-03-2018 IPR023992 Heme D1 biosynthesis, radical SAM protein NirJ AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 Gene3D G3DSA:3.20.20.70 13 336 5.2E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 PIRSF PIRSF037420 11 377 1.1E-128 T 28-03-2018 AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 Pfam PF04055 Radical SAM superfamily 30 179 1.5E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 SUPERFAMILY SSF102114 24 348 4.71E-64 T 28-03-2018 AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 Pfam PF13353 4Fe-4S single cluster domain 27 112 2.2E-8 T 28-03-2018 AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 284 368 3.7E-8 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain AFA_RS11250 2a170080901fec7e5dfc06c38a6d325a 377 Pfam PF13186 Iron-sulfur cluster-binding domain 282 340 1.6E-4 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain AFA_RS07150 f68dda57e2f741c9d29971195ae7da73 152 Pfam PF00959 Phage lysozyme 36 141 4.9E-17 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 AFA_RS07150 f68dda57e2f741c9d29971195ae7da73 152 Gene3D G3DSA:1.10.530.40 3 151 4.1E-47 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 AFA_RS07150 f68dda57e2f741c9d29971195ae7da73 152 SUPERFAMILY SSF53955 7 151 5.63E-48 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 Pfam PF00231 ATP synthase 4 301 4.2E-89 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 288 301 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 302 34.43 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 9.7E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 9.7E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 PRINTS PR00126 ATP synthase gamma subunit signature 249 268 9.7E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 PRINTS PR00126 ATP synthase gamma subunit signature 280 301 9.7E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 Gene3D G3DSA:1.10.287.80 256 297 1.4E-12 T 28-03-2018 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 Gene3D G3DSA:1.10.287.80 5 160 2.2E-43 T 28-03-2018 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 302 5.8E-98 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 Gene3D G3DSA:1.10.287.80 161 255 1.9E-21 T 28-03-2018 AFA_RS16605 a02314c6993e9aec54e5b19faf627d37 302 SUPERFAMILY SSF52943 2 302 3.79E-88 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS05770 586ebe9ac7b77e6c5daa8d06c2ec2801 129 Pfam PF00072 Response regulator receiver domain 8 120 1.1E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS05770 586ebe9ac7b77e6c5daa8d06c2ec2801 129 SUPERFAMILY SSF52172 4 125 2.42E-37 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS05770 586ebe9ac7b77e6c5daa8d06c2ec2801 129 Gene3D G3DSA:3.40.50.2300 1 128 2.3E-38 T 28-03-2018 AFA_RS05770 586ebe9ac7b77e6c5daa8d06c2ec2801 129 SMART SM00448 6 120 3.6E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 Gene3D G3DSA:4.10.520.10 1 90 2.6E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.8E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.5E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.5E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.5E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 SMART SM00411 1 90 1.3E-43 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11215 3697418f511d41b6d733a390af047a99 90 SUPERFAMILY SSF47729 1 90 3.83E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Gene3D G3DSA:3.40.50.920 491 617 8.5E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 278 4.9E-118 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Pfam PF02779 Transketolase, pyrimidine binding domain 316 474 5.1E-37 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Gene3D G3DSA:3.40.50.970 293 483 1.1E-61 T 28-03-2018 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Pfam PF02780 Transketolase, C-terminal domain 491 607 8.9E-30 T 28-03-2018 IPR033248 Transketolase, C-terminal domain AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Gene3D G3DSA:3.40.50.970 1 292 1.9E-79 T 28-03-2018 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 SMART SM00861 315 479 2.5E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 613 3.4E-262 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 616 45.463 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 SUPERFAMILY SSF52518 6 195 2.72E-74 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 SUPERFAMILY SSF52518 239 377 2.72E-74 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 SUPERFAMILY SSF52518 313 500 5.42E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS05185 0fb8649ae39a2b6a3e39d9efa810814e 621 SUPERFAMILY SSF52922 487 615 6.41E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS05870 31c365833ea91c137c3f07271d57b78d 405 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 8.7E-10 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFA_RS05870 31c365833ea91c137c3f07271d57b78d 405 SUPERFAMILY SSF64518 1 402 4.71E-54 T 28-03-2018 AFA_RS05870 31c365833ea91c137c3f07271d57b78d 405 Gene3D G3DSA:1.20.1330.10 42 370 4.4E-18 T 28-03-2018 AFA_RS05870 31c365833ea91c137c3f07271d57b78d 405 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 402 3.0E-73 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 AFA_RS14520 24321f31869b863512b269ea866ec03a 321 SMART SM00450 180 301 8.5E-8 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 SMART SM00450 38 156 3.8E-18 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 SUPERFAMILY SSF52821 33 174 7.6E-31 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 Gene3D G3DSA:3.40.250.10 174 319 2.6E-18 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 Gene3D G3DSA:3.40.250.10 28 173 2.4E-31 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 SUPERFAMILY SSF52821 174 303 1.07E-21 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 Pfam PF00581 Rhodanese-like domain 39 152 4.6E-15 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS14520 24321f31869b863512b269ea866ec03a 321 Pfam PF00581 Rhodanese-like domain 181 297 8.0E-8 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS13990 f0715c40ac32a04adc663cf6d5b354d3 417 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 225 327 5.2E-6 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 AFA_RS13990 f0715c40ac32a04adc663cf6d5b354d3 417 Gene3D G3DSA:1.10.287.460 220 320 5.6E-4 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 AFA_RS13990 f0715c40ac32a04adc663cf6d5b354d3 417 Gene3D G3DSA:1.20.5.50 59 208 9.7E-4 T 28-03-2018 AFA_RS13990 f0715c40ac32a04adc663cf6d5b354d3 417 Gene3D G3DSA:3.10.50.40 321 417 4.5E-4 T 28-03-2018 AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Gene3D G3DSA:2.60.40.420 47 153 1.2E-20 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Gene3D G3DSA:2.60.40.420 154 196 8.3E-10 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 SUPERFAMILY SSF49503 416 531 9.87E-36 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Pfam PF07732 Multicopper oxidase 88 200 1.1E-31 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 SUPERFAMILY SSF49503 92 201 3.25E-33 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 ProSitePatterns PS00080 Multicopper oxidases signature 2. 514 525 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Gene3D G3DSA:2.60.40.420 197 344 8.5E-17 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 SUPERFAMILY SSF49503 206 313 2.34E-14 T 28-03-2018 IPR008972 Cupredoxin AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Pfam PF07731 Multicopper oxidase 421 531 2.6E-31 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AFA_RS09515 40d37370e744b9f340664c6f421f5400 532 Gene3D G3DSA:2.60.40.420 355 532 2.0E-34 T 28-03-2018 IPR008972 Cupredoxin AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 Pfam PF04321 RmlD substrate binding domain 48 325 1.9E-92 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 Gene3D G3DSA:3.40.50.720 2 197 2.2E-18 T 28-03-2018 AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 51 323 6.7E-93 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 SUPERFAMILY SSF51735 57 323 7.3E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 SUPERFAMILY SSF51735 1 29 7.3E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 Gene3D G3DSA:3.90.25.10 227 311 3.4E-21 T 28-03-2018 AFA_RS16590 37f04766ab3a812c324b83d9e875b0d4 330 Gene3D G3DSA:3.90.25.10 198 226 5.5E-7 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Gene3D G3DSA:3.40.50.1000 635 777 1.5E-45 T 28-03-2018 IPR023214 HAD-like domain AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Gene3D G3DSA:1.20.1110.10 267 521 6.0E-46 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 508 514 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF55008 78 145 1.2E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 45 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 ProSitePatterns PS01047 Heavy-metal-associated domain. 83 112 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF81653 306 404 6.93E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 219 815 4.7E-180 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF81665 269 308 5.62E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF81665 754 793 5.62E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF81665 405 500 5.62E-15 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Pfam PF00122 E1-E2 ATPase 304 485 8.7E-58 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Gene3D G3DSA:3.40.1110.10 522 634 5.7E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Pfam PF00403 Heavy-metal-associated domain 80 139 1.2E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Pfam PF00403 Heavy-metal-associated domain 13 73 7.7E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Gene3D G3DSA:3.30.70.100 12 76 4.5E-24 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 237 814 3.8E-191 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Gene3D G3DSA:3.30.70.100 77 147 8.3E-22 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 12 74 5.2E-16 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 81 140 4.7E-9 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 276 783 8.7E-95 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 354 368 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 520 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 662 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 728 740 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 705 724 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 641 3.5E-29 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF56784 563 812 1.49E-60 T 28-03-2018 IPR023214 HAD-like domain AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF56784 504 524 1.49E-60 T 28-03-2018 IPR023214 HAD-like domain AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 Pfam PF00702 haloacid dehalogenase-like hydrolase 502 719 1.1E-43 T 28-03-2018 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00941 Cadmium-transporting ATPase signature 309 325 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00941 Cadmium-transporting ATPase signature 14 23 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00941 Cadmium-transporting ATPase signature 389 403 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 PRINTS PR00941 Cadmium-transporting ATPase signature 370 386 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS09495 16d0ab359400d853db977c6b63de3e32 820 SUPERFAMILY SSF55008 8 75 6.41E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 Pfam PF09339 IclR helix-turn-helix domain 14 61 6.2E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 Pfam PF01614 Bacterial transcriptional regulator 130 248 2.5E-18 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 SUPERFAMILY SSF46785 10 81 6.72E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 SMART SM00346 10 100 6.4E-4 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 SUPERFAMILY SSF55781 85 249 4.58E-36 T 28-03-2018 IPR029016 GAF domain-like AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 Gene3D G3DSA:3.30.450.40 97 251 6.8E-36 T 28-03-2018 IPR029016 GAF domain-like AFA_RS02120 05d6d8b4fd960a83fc5921b05b1394dd 251 Gene3D G3DSA:1.10.10.10 2 96 1.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05325 9e9fb5e5170f289e7918148ecabe02e5 268 Gene3D G3DSA:1.10.3720.10 6 268 2.5E-40 T 28-03-2018 AFA_RS05325 9e9fb5e5170f289e7918148ecabe02e5 268 SUPERFAMILY SSF161098 6 265 1.4E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05325 9e9fb5e5170f289e7918148ecabe02e5 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 265 8.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 SUPERFAMILY SSF46785 21 88 2.08E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 SUPERFAMILY SSF53383 126 491 1.62E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 Pfam PF00155 Aminotransferase class I and II 161 485 4.0E-19 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.6E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.6E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 Gene3D G3DSA:1.10.10.10 5 88 7.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 1.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 SMART SM00345 27 86 3.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 Gene3D G3DSA:3.90.1150.10 394 493 1.7E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS12095 87de7472c910dc5fc55b2c3050a961bc 502 Gene3D G3DSA:3.40.640.10 152 393 1.9E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 299 3.6E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 509 536 0.29 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 SUPERFAMILY SSF52540 283 529 2.17E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 SUPERFAMILY SSF52540 25 262 4.24E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Gene3D G3DSA:3.40.50.300 281 537 5.5E-70 T 28-03-2018 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Gene3D G3DSA:3.40.50.300 8 280 4.6E-66 T 28-03-2018 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 SMART SM00382 316 507 5.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 SMART SM00382 39 240 2.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Pfam PF00005 ABC transporter 31 190 1.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 Pfam PF00005 ABC transporter 307 456 8.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08920 016019edcca1e1fffc38c14cc8a6f470 547 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS05410 6a02a2d312ae832603416914ffa5482d 301 Gene3D G3DSA:3.40.50.2000 1 125 1.2E-12 T 28-03-2018 AFA_RS05410 6a02a2d312ae832603416914ffa5482d 301 SUPERFAMILY SSF53756 1 288 3.87E-37 T 28-03-2018 AFA_RS05410 6a02a2d312ae832603416914ffa5482d 301 Gene3D G3DSA:3.40.50.2000 141 297 4.5E-24 T 28-03-2018 AFA_RS05410 6a02a2d312ae832603416914ffa5482d 301 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 63 282 2.4E-39 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 AFA_RS00340 c69755ee5aa40a160b40dc32ec80f1f5 167 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 35 166 8.8E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS01115 9c2faf978af40c06ebff304545faa6e9 426 Gene3D G3DSA:3.40.50.980 122 264 9.5E-12 T 28-03-2018 AFA_RS01115 9c2faf978af40c06ebff304545faa6e9 426 Gene3D G3DSA:3.30.300.30 329 421 2.4E-6 T 28-03-2018 AFA_RS01115 9c2faf978af40c06ebff304545faa6e9 426 Pfam PF00501 AMP-binding enzyme 158 291 9.9E-12 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS01115 9c2faf978af40c06ebff304545faa6e9 426 SUPERFAMILY SSF56801 128 396 8.37E-32 T 28-03-2018 AFA_RS01115 9c2faf978af40c06ebff304545faa6e9 426 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 416 4.6E-6 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Gene3D G3DSA:3.40.50.300 25 194 9.0E-30 T 28-03-2018 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Pfam PF01926 50S ribosome-binding GTPase 11 124 7.4E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 166 1.5E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 SUPERFAMILY SSF52540 11 202 9.52E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Hamap MF_00367 GTPase Era [era]. 6 295 33.275 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 79 97 6.5E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 6.5E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Gene3D G3DSA:3.30.300.20 195 296 1.7E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Pfam PF07650 KH domain 208 283 7.0E-14 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 SUPERFAMILY SSF54814 182 296 1.11E-34 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 Gene3D G3DSA:3.40.50.300 7 24 0.012 T 28-03-2018 AFA_RS13055 8f352becd7595dc26caf50beac03fb2a 296 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 278 1.1E-76 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS04515 5162ddd736a34061e4e1773f1f99da9a 282 SUPERFAMILY SSF75217 7 178 3.2E-31 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS04515 5162ddd736a34061e4e1773f1f99da9a 282 Pfam PF00588 SpoU rRNA Methylase family 16 169 4.0E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFA_RS04515 5162ddd736a34061e4e1773f1f99da9a 282 PIRSF PIRSF004808 11 265 4.2E-60 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AFA_RS04515 5162ddd736a34061e4e1773f1f99da9a 282 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 15 258 1.0E-52 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AFA_RS04515 5162ddd736a34061e4e1773f1f99da9a 282 Gene3D G3DSA:3.40.1280.10 2 181 4.5E-37 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 SMART SM01274 20 154 2.3E-77 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 PIRSF PIRSF036684 1 761 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Pfam PF03949 Malic enzyme, NAD binding domain 168 363 4.5E-21 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 SUPERFAMILY SSF53223 13 164 4.24E-50 T 28-03-2018 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Pfam PF01515 Phosphate acetyl/butaryl transferase 433 753 4.1E-98 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 SUPERFAMILY SSF53659 432 756 2.63E-89 T 28-03-2018 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 SMART SM00919 166 403 1.5E-137 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Gene3D G3DSA:3.40.50.720 164 449 2.1E-82 T 28-03-2018 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 SUPERFAMILY SSF51735 166 445 6.81E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Gene3D G3DSA:3.40.718.10 450 727 4.3E-55 T 28-03-2018 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Pfam PF00390 Malic enzyme, N-terminal domain 21 154 3.5E-28 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS04885 7557b7a63cf50c38735d29632960bea6 764 Gene3D G3DSA:3.40.50.10380 7 163 2.4E-34 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS00845 369687f1ceeff2f0915403000e007000 206 Pfam PF04011 LemA family 11 195 1.0E-57 T 28-03-2018 IPR007156 LemA AFA_RS00845 369687f1ceeff2f0915403000e007000 206 SUPERFAMILY SSF140478 25 182 6.28E-48 T 28-03-2018 IPR023353 LemA-like domain AFA_RS00845 369687f1ceeff2f0915403000e007000 206 Gene3D G3DSA:1.20.1440.20 13 195 2.0E-49 T 28-03-2018 AFA_RS10515 4a21e27e440515848dfe08b076569cd1 284 Gene3D G3DSA:3.40.50.150 1 283 1.6E-82 T 28-03-2018 AFA_RS10515 4a21e27e440515848dfe08b076569cd1 284 SUPERFAMILY SSF53335 9 280 4.39E-84 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS10515 4a21e27e440515848dfe08b076569cd1 284 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 271 37.667 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AFA_RS10515 4a21e27e440515848dfe08b076569cd1 284 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 277 9.5E-70 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AFA_RS18515 cb8ad7e4f4743d1e9515b0c749795ae7 334 Gene3D G3DSA:3.30.1780.10 4 145 3.9E-36 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFA_RS18515 cb8ad7e4f4743d1e9515b0c749795ae7 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 7 319 1.3E-70 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS18515 cb8ad7e4f4743d1e9515b0c749795ae7 334 SUPERFAMILY SSF51735 7 334 2.96E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS18515 cb8ad7e4f4743d1e9515b0c749795ae7 334 PIRSF PIRSF001439 1 334 3.3E-79 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS18515 cb8ad7e4f4743d1e9515b0c749795ae7 334 Gene3D G3DSA:3.40.50.720 146 307 5.7E-30 T 28-03-2018 AFA_RS09335 e069e02a11bbf2dd4200f6e8fe7d75ba 347 Gene3D G3DSA:3.40.190.10 29 160 1.4E-17 T 28-03-2018 AFA_RS09335 e069e02a11bbf2dd4200f6e8fe7d75ba 347 Pfam PF13343 Bacterial extracellular solute-binding protein 79 306 6.4E-18 T 28-03-2018 AFA_RS09335 e069e02a11bbf2dd4200f6e8fe7d75ba 347 Gene3D G3DSA:3.40.190.10 161 321 3.4E-18 T 28-03-2018 AFA_RS09335 e069e02a11bbf2dd4200f6e8fe7d75ba 347 PIRSF PIRSF002825 3 347 3.5E-80 T 28-03-2018 IPR026045 Ferric binding protein AFA_RS09335 e069e02a11bbf2dd4200f6e8fe7d75ba 347 SUPERFAMILY SSF53850 30 344 4.06E-72 T 28-03-2018 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 SUPERFAMILY SSF161098 325 582 2.49E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 421 580 1.5E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 307 1.2E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 Gene3D G3DSA:1.10.3720.10 328 592 1.1E-23 T 28-03-2018 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 Gene3D G3DSA:1.10.3720.10 50 312 1.3E-34 T 28-03-2018 AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 48 595 1.9E-231 T 28-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative AFA_RS11360 b387b67334b5abb48042448bc0a2d6b3 603 SUPERFAMILY SSF161098 48 300 4.02E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS06635 5c7f0f8322abfd235f9b72e399539208 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 31.548 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFA_RS06635 5c7f0f8322abfd235f9b72e399539208 152 SUPERFAMILY SSF69500 1 143 2.09E-50 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain AFA_RS06635 5c7f0f8322abfd235f9b72e399539208 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 1.8E-49 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFA_RS06635 5c7f0f8322abfd235f9b72e399539208 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 3.2E-51 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFA_RS06635 5c7f0f8322abfd235f9b72e399539208 152 Gene3D G3DSA:3.50.80.10 1 145 3.7E-50 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain AFA_RS15765 5a36632cec649f4762ad736ab330e62e 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.7E-36 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15765 5a36632cec649f4762ad736ab330e62e 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS15765 5a36632cec649f4762ad736ab330e62e 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.066 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15765 5a36632cec649f4762ad736ab330e62e 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 3.4E-40 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15765 5a36632cec649f4762ad736ab330e62e 103 SUPERFAMILY SSF141091 1 102 4.19E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 SUPERFAMILY SSF54292 237 355 8.26E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 PRINTS PR00406 Cytochrome B5 reductase signature 91 105 1.6E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 PRINTS PR00406 Cytochrome B5 reductase signature 116 135 1.6E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 PRINTS PR00406 Cytochrome B5 reductase signature 153 164 1.6E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 PRINTS PR00406 Cytochrome B5 reductase signature 212 220 1.6E-7 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 274 347 2.6E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Pfam PF00175 Oxidoreductase NAD-binding domain 119 225 3.5E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 SUPERFAMILY SSF52343 94 242 6.29E-31 T 28-03-2018 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Gene3D G3DSA:2.40.30.10 1 93 5.5E-20 T 28-03-2018 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Pfam PF00970 Oxidoreductase FAD-binding domain 8 103 6.7E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 357 1.5E-139 T 28-03-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 305 313 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Gene3D G3DSA:3.40.50.80 94 237 1.5E-27 T 28-03-2018 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 SUPERFAMILY SSF63380 2 105 1.15E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS11835 60c87223362ab2d01995e16cc15a229a 360 Gene3D G3DSA:3.10.20.30 238 360 5.9E-30 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS02615 4ccf600b195f6b144fbdb3608fc4b40d 196 SUPERFAMILY SSF46626 17 184 4.98E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02615 4ccf600b195f6b144fbdb3608fc4b40d 196 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 13 149 7.8E-35 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AFA_RS02615 4ccf600b195f6b144fbdb3608fc4b40d 196 Gene3D G3DSA:1.10.760.10 28 193 1.6E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 Gene3D G3DSA:2.30.40.10 4 69 8.8E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 Gene3D G3DSA:3.20.20.140 70 358 4.3E-62 T 28-03-2018 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 SUPERFAMILY SSF51338 377 447 2.84E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 SUPERFAMILY SSF51338 6 55 2.84E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 Gene3D G3DSA:2.30.40.10 359 439 5.1E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 Pfam PF01979 Amidohydrolase family 53 429 2.2E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS01635 07d8b52830e0337b3f76f5c9b582b300 455 SUPERFAMILY SSF51556 56 377 7.9E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 Gene3D G3DSA:3.40.190.80 207 341 3.2E-54 T 28-03-2018 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 Gene3D G3DSA:3.30.540.10 13 206 1.3E-56 T 28-03-2018 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PIRSF PIRSF500210 5 341 2.6E-124 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 SUPERFAMILY SSF56655 9 338 1.22E-111 T 28-03-2018 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 11 201 4.1E-58 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 9 340 45.372 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 212 239 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 71 97 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 314 339 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 155 178 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 186 209 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 34 61 3.0E-70 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS12670 c33e72654a3e5995da6c275bf52c88ee 341 PIRSF PIRSF000904 5 341 3.3E-122 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFA_RS16365 d17026eb9a7d4bcb891592be133e420c 291 PIRSF PIRSF005052 2 287 4.9E-105 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 AFA_RS16365 d17026eb9a7d4bcb891592be133e420c 291 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 286 38.965 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 AFA_RS16365 d17026eb9a7d4bcb891592be133e420c 291 Gene3D G3DSA:3.40.50.300 2 166 8.3E-9 T 28-03-2018 AFA_RS16365 d17026eb9a7d4bcb891592be133e420c 291 Pfam PF03668 P-loop ATPase protein family 3 282 1.3E-83 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 AFA_RS16365 d17026eb9a7d4bcb891592be133e420c 291 SUPERFAMILY SSF52540 3 159 2.06E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Gene3D G3DSA:3.40.50.980 24 178 2.3E-25 T 28-03-2018 AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Pfam PF00501 AMP-binding enzyme 33 442 2.6E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Gene3D G3DSA:2.30.38.10 345 434 6.9E-19 T 28-03-2018 AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Gene3D G3DSA:3.40.50.980 179 344 1.5E-26 T 28-03-2018 AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 528 8.2E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 SUPERFAMILY SSF56801 16 538 7.85E-113 T 28-03-2018 AFA_RS08180 f4b9854bd4fbc5a3c2d69072a4d53341 553 Gene3D G3DSA:3.30.300.30 435 539 5.9E-22 T 28-03-2018 AFA_RS08315 9d960794b9db8444f8dc73cfa58edefa 159 Gene3D G3DSA:1.20.58.280 3 38 0.0035 T 28-03-2018 AFA_RS08315 9d960794b9db8444f8dc73cfa58edefa 159 SUPERFAMILY SSF48452 23 88 7.32E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS08315 9d960794b9db8444f8dc73cfa58edefa 159 Gene3D G3DSA:1.25.40.10 39 136 8.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 121 134 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 SMART SM00839 203 444 1.3E-97 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 SUPERFAMILY SSF51735 201 446 1.34E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 444 3.2E-88 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 SUPERFAMILY SSF53223 6 195 8.32E-74 T 28-03-2018 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 56 183 3.1E-50 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Gene3D G3DSA:3.40.50.10860 62 189 8.2E-55 T 28-03-2018 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Gene3D G3DSA:1.10.285.10 5 61 3.9E-7 T 28-03-2018 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Gene3D G3DSA:1.10.285.10 373 446 3.4E-29 T 28-03-2018 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 Gene3D G3DSA:3.40.50.720 208 372 1.6E-43 T 28-03-2018 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 PIRSF PIRSF000185 21 446 8.4E-116 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 2.8E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 2.8E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 2.8E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS11695 cbf67e4486b260a79a451e6731758676 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 113 127 2.8E-31 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 Pfam PF00171 Aldehyde dehydrogenase family 25 296 6.1E-21 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 PIRSF PIRSF000151 13 431 1.6E-175 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 27 420 1.4E-145 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 Gene3D G3DSA:3.40.605.10 260 431 5.1E-40 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 SUPERFAMILY SSF53720 19 430 1.17E-117 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 Gene3D G3DSA:3.40.605.10 7 259 5.7E-45 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 337 358 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS12850 fbada5a7c5fecd1620075495c58903d2 431 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 19 430 40.922 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Gene3D G3DSA:3.10.290.10 322 408 1.5E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 17 405 3.4E-121 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Gene3D G3DSA:3.40.50.620 8 230 3.7E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 64 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Gene3D G3DSA:1.10.240.10 231 321 8.9E-28 T 28-03-2018 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 9.8E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 9.8E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 9.8E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 58 80 9.8E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Pfam PF01479 S4 domain 348 390 1.2E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Pfam PF00579 tRNA synthetases class I (W and Y) 44 328 8.6E-75 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 SUPERFAMILY SSF52374 19 328 9.01E-92 T 28-03-2018 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 10 406 48.335 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 SMART SM00363 346 407 8.0E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS15490 71d685107a0bd0e029d90beaa2a9d362 408 SUPERFAMILY SSF55174 310 405 1.7E-19 T 28-03-2018 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 SMART SM00866 88 226 4.4E-13 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 Pfam PF07702 UTRA domain 89 226 8.6E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 SUPERFAMILY SSF64288 57 231 1.22E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 Gene3D G3DSA:3.40.1410.10 75 233 1.3E-24 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 SUPERFAMILY SSF46785 2 73 1.02E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 4.4E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 SMART SM00345 10 69 1.9E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS02235 15c0a5dc3778d6082971a0291710d79b 234 Gene3D G3DSA:1.10.10.10 2 74 4.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 SUPERFAMILY SSF53822 29 381 3.77E-85 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 Gene3D G3DSA:3.40.50.2300 16 198 3.2E-32 T 28-03-2018 AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 Pfam PF13458 Periplasmic binding protein 29 369 2.2E-71 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 2.5E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 2.5E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 338 353 2.5E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 262 280 2.5E-6 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS15000 e042a2cd5a12d3a2b34a1703119ec18d 405 Gene3D G3DSA:3.40.50.2300 199 363 2.6E-18 T 28-03-2018 AFA_RS01230 e5e059cad96dd8d08f3318fe462e9cff 290 Gene3D G3DSA:3.20.10.10 127 288 2.3E-32 T 28-03-2018 AFA_RS01230 e5e059cad96dd8d08f3318fe462e9cff 290 Gene3D G3DSA:3.30.470.10 6 126 4.6E-32 T 28-03-2018 AFA_RS01230 e5e059cad96dd8d08f3318fe462e9cff 290 SUPERFAMILY SSF56752 8 282 9.29E-74 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS01230 e5e059cad96dd8d08f3318fe462e9cff 290 Pfam PF01063 Amino-transferase class IV 37 256 2.2E-42 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS16040 28b41cc9fd6e4caecbd6aaa0a97473a4 288 Gene3D G3DSA:3.40.50.300 68 198 6.6E-13 T 28-03-2018 AFA_RS16040 28b41cc9fd6e4caecbd6aaa0a97473a4 288 Pfam PF05673 Protein of unknown function (DUF815) 35 286 2.6E-103 T 28-03-2018 IPR008533 Domain of unknown function DUF815 AFA_RS16040 28b41cc9fd6e4caecbd6aaa0a97473a4 288 SUPERFAMILY SSF52540 45 194 2.67E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13645 7237d33ef0a82ca0d60c659a871b42a4 690 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 18 64 5.3E-7 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Gene3D G3DSA:3.30.1490.100 282 399 2.8E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Gene3D G3DSA:1.10.150.20 208 281 1.2E-18 T 28-03-2018 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 SUPERFAMILY SSF100879 280 385 8.63E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Pfam PF00817 impB/mucB/samB family 28 192 1.5E-40 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Gene3D G3DSA:3.30.70.270 82 157 5.5E-14 T 28-03-2018 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Gene3D G3DSA:3.30.70.270 158 207 1.6E-17 T 28-03-2018 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Hamap MF_01113 DNA polymerase IV [dinB]. 22 397 32.312 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 Pfam PF11799 impB/mucB/samB family C-terminal domain 274 386 9.7E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFA_RS00435 1ef9eb7b51dec910e99031236af640bb 401 SUPERFAMILY SSF56672 14 272 7.83E-72 T 28-03-2018 AFA_RS14340 4bbc09b6d04d61c6de9724667252881e 241 SUPERFAMILY SSF55729 89 239 1.52E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS14340 4bbc09b6d04d61c6de9724667252881e 241 PIRSF PIRSF037208 5 241 3.6E-87 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 AFA_RS14340 4bbc09b6d04d61c6de9724667252881e 241 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 21 91 2.4E-19 T 28-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 AFA_RS14340 4bbc09b6d04d61c6de9724667252881e 241 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 111 232 3.4E-38 T 28-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 AFA_RS14340 4bbc09b6d04d61c6de9724667252881e 241 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 6 241 43.566 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 AFA_RS00360 4dfa3cc137c8670888ea8d797d8362c1 295 Pfam PF13557 Putative MetA-pathway of phenol degradation 60 290 9.2E-61 T 28-03-2018 IPR025737 MetA-pathway of phenol degradation, putative AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Pfam PF13241 Putative NAD(P)-binding 6 115 4.7E-25 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 9.4E-15 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 SUPERFAMILY SSF53790 229 268 5.09E-6 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Gene3D G3DSA:3.30.160.110 121 148 5.7E-14 T 28-03-2018 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Gene3D G3DSA:1.10.8.210 151 207 2.9E-13 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 SUPERFAMILY SSF75615 114 212 4.32E-24 T 28-03-2018 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 SUPERFAMILY SSF51735 1 109 2.68E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Gene3D G3DSA:3.40.1010.10 208 305 0.0013 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 9.6E-7 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 Gene3D G3DSA:3.40.50.720 3 120 1.0E-23 T 28-03-2018 AFA_RS11260 bfd26761b7cedccf10bbb053bfbe1e75 326 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 2.6E-64 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 SMART SM00116 79 126 0.03 T 28-03-2018 IPR000644 CBS domain AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 SMART SM00116 14 61 5.1E-6 T 28-03-2018 IPR000644 CBS domain AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 Gene3D G3DSA:3.10.580.10 1 136 3.3E-23 T 28-03-2018 AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 SUPERFAMILY SSF54631 3 143 1.89E-27 T 28-03-2018 AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 Pfam PF00571 CBS domain 72 127 1.0E-7 T 28-03-2018 IPR000644 CBS domain AFA_RS10855 50e1d8bd7f9b4691ca8f629f7411a7bc 153 Pfam PF00571 CBS domain 19 60 7.5E-6 T 28-03-2018 IPR000644 CBS domain AFA_RS16490 f6d9568749f5c04ced80541459534950 434 Gene3D G3DSA:1.10.940.10 3 150 1.2E-19 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 SUPERFAMILY SSF48013 8 154 1.35E-9 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 SUPERFAMILY SSF53335 146 432 8.21E-68 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16490 f6d9568749f5c04ced80541459534950 434 Gene3D G3DSA:3.40.50.150 234 434 2.1E-48 T 28-03-2018 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 Gene3D G3DSA:1.10.287.730 151 176 2.6E-9 T 28-03-2018 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 Gene3D G3DSA:3.30.70.1170 178 233 1.9E-10 T 28-03-2018 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 428 3.0E-52 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 99 429 3.1E-87 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 1.3E-21 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 415 432 1.3E-21 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 1.3E-21 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 1.3E-21 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS16490 f6d9568749f5c04ced80541459534950 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 1.3E-21 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 SUPERFAMILY SSF52343 456 610 9.17E-50 T 28-03-2018 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Pfam PF00667 FAD binding domain 241 436 1.9E-31 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Pfam PF00175 Oxidoreductase NAD-binding domain 468 574 1.6E-19 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 SUPERFAMILY SSF63380 239 457 1.38E-63 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 467 486 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 280 290 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 559 567 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 431 440 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 398 405 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 505 516 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 492 501 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 536 552 6.3E-29 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Pfam PF00258 Flavodoxin 71 194 7.8E-29 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00369 Flavodoxin signature 118 129 3.8E-16 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00369 Flavodoxin signature 70 83 3.8E-16 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00369 Flavodoxin signature 174 193 3.8E-16 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PRINTS PR00369 Flavodoxin signature 150 160 3.8E-16 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 PIRSF PIRSF000207 1 610 7.9E-217 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 610 1.4E-228 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Gene3D G3DSA:3.40.50.360 47 228 2.0E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Gene3D G3DSA:3.40.50.80 453 609 5.9E-37 T 28-03-2018 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 Gene3D G3DSA:2.40.30.10 230 449 1.2E-47 T 28-03-2018 AFA_RS18180 fe327304cac07b808b1376370f7b3238 610 SUPERFAMILY SSF52218 67 211 1.94E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 Gene3D G3DSA:3.30.1150.10 91 243 3.5E-22 T 28-03-2018 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 167 241 1.9E-23 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 167 241 5.1E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 Pfam PF16031 TonB N-terminal region 35 146 3.5E-8 T 28-03-2018 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 SUPERFAMILY SSF74653 164 241 1.44E-22 T 28-03-2018 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 95 105 1.1E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 182 200 1.1E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFA_RS11160 68a85c55154cc89db147ea223b0db7f6 243 PRINTS PR01374 Gram-negative bacterial tonB protein signature 161 182 1.1E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 SUPERFAMILY SSF111369 56 288 9.29E-17 T 28-03-2018 AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 Gene3D G3DSA:2.40.50.100 179 362 3.8E-5 T 28-03-2018 AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 286 8.6E-17 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 Gene3D G3DSA:1.10.287.470 128 170 7.8E-5 T 28-03-2018 AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 Gene3D G3DSA:2.40.50.100 64 127 1.4E-14 T 28-03-2018 AFA_RS12335 0fd523b00999b57fc27a0f5ea70430e8 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 374 2.5E-51 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 Pfam PF00266 Aminotransferase class-V 7 367 6.6E-85 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 PIRSF PIRSF005572 4 384 2.0E-128 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 Gene3D G3DSA:3.40.640.10 15 262 2.7E-67 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 SUPERFAMILY SSF53383 5 381 5.0E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 3 395 50.364 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AFA_RS07715 7849356c39357a2f33c6ebbd95e4822d 397 Gene3D G3DSA:3.90.1150.10 269 384 3.1E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:3.30.56.10 400 473 2.1E-22 T 28-03-2018 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 800 3.1E-232 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:2.40.50.140 38 140 3.6E-43 T 28-03-2018 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SUPERFAMILY SSF50249 36 198 2.45E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:3.50.40.10 196 396 7.0E-62 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SUPERFAMILY SSF46955 401 473 1.28E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Pfam PF03484 tRNA synthetase B5 domain 404 469 1.7E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SMART SM00896 703 800 1.6E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:3.30.930.10 491 692 3.1E-42 T 28-03-2018 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 794 42.734 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SMART SM00873 212 385 2.0E-78 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SMART SM00874 401 469 2.5E-27 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SUPERFAMILY SSF54991 698 800 2.88E-19 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Pfam PF03147 Ferredoxin-fold anticodon binding domain 703 800 2.4E-22 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Pfam PF01588 Putative tRNA binding domain 45 145 1.5E-24 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:3.30.56.10 141 184 5.8E-10 T 28-03-2018 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SUPERFAMILY SSF56037 195 391 1.94E-64 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 SUPERFAMILY SSF55681 465 691 4.67E-53 T 28-03-2018 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Pfam PF03483 B3/4 domain 213 385 1.1E-59 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFA_RS08735 94c9bb465ee3cfeef9bc598efc1a6db7 801 Gene3D G3DSA:3.30.70.380 700 800 1.1E-18 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 3.1E-38 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 PIRSF PIRSF000103 1 291 6.5E-73 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 Gene3D G3DSA:3.40.50.720 1 163 5.8E-33 T 28-03-2018 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 1.0E-47 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 Gene3D G3DSA:1.10.1040.10 164 293 7.8E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 SUPERFAMILY SSF48179 163 291 1.13E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 3 291 5.8E-122 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 AFA_RS02655 e686eec8ab70b2155789b839487ad420 294 SUPERFAMILY SSF51735 2 162 8.19E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16130 d5cee3892be6c43ed27593e23d52b814 276 Pfam PF13560 Helix-turn-helix domain 21 100 2.0E-16 T 28-03-2018 AFA_RS16130 d5cee3892be6c43ed27593e23d52b814 276 SUPERFAMILY SSF47413 44 93 1.9E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS16130 d5cee3892be6c43ed27593e23d52b814 276 Gene3D G3DSA:1.10.260.40 12 115 8.0E-15 T 28-03-2018 AFA_RS16130 d5cee3892be6c43ed27593e23d52b814 276 SMART SM00530 25 97 1.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 3.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 SUPERFAMILY SSF53383 93 454 1.14E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 Gene3D G3DSA:3.90.1150.10 343 459 5.3E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 Gene3D G3DSA:1.10.10.10 1 71 7.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 SUPERFAMILY SSF46785 3 72 5.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 Pfam PF00155 Aminotransferase class I and II 132 450 2.9E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 SMART SM00345 10 69 6.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17055 4ebf4785c3bebbd97ee51f3ac9c9324f 463 Gene3D G3DSA:3.40.640.10 130 342 1.9E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 113 8.9E-16 T 28-03-2018 IPR000014 PAS domain AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 335 491 8.5E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 Gene3D G3DSA:3.40.50.10600 8 132 7.8E-29 T 28-03-2018 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 SMART SM00283 276 523 1.6E-65 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 Gene3D G3DSA:1.10.287.950 326 526 6.7E-43 T 28-03-2018 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 Gene3D G3DSA:1.10.287.950 227 325 3.7E-7 T 28-03-2018 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 SMART SM00086 80 121 0.0058 T 28-03-2018 IPR001610 PAC motif AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 SUPERFAMILY SSF55785 20 114 1.68E-27 T 28-03-2018 IPR000014 PAS domain AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 SUPERFAMILY SSF58104 246 524 6.15E-57 T 28-03-2018 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 297 326 1.0E-39 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 374 401 1.0E-39 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 451 480 1.0E-39 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 403 432 1.0E-39 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS12465 39ab80c0d006e486c3ffe84c98bfd0d3 564 Pfam PF08447 PAS fold 30 113 7.0E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 5.4E-13 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 5.4E-13 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 183 193 5.4E-13 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 199 207 5.4E-13 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 5.4E-13 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 12 248 1.0E-38 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 SUPERFAMILY SSF52374 9 269 4.15E-78 T 28-03-2018 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 9 271 7.9E-109 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 Gene3D G3DSA:3.40.50.620 119 235 2.8E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 9 295 40.04 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 AFA_RS00665 0cd3180262b3ba71afed3fad232729e1 297 Gene3D G3DSA:3.40.50.620 10 118 1.7E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 Gene3D G3DSA:1.20.1250.20 8 224 9.5E-23 T 28-03-2018 AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 Gene3D G3DSA:1.20.1250.20 225 429 2.0E-20 T 28-03-2018 AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 Pfam PF00083 Sugar (and other) transporter 18 230 1.7E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 SUPERFAMILY SSF103473 15 427 6.15E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 Pfam PF07690 Major Facilitator Superfamily 256 425 2.9E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS13880 11c59d1c59c414f17b23c5a26105f30d 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 Gene3D G3DSA:3.30.450.40 92 267 1.3E-46 T 28-03-2018 IPR029016 GAF domain-like AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 SMART SM00346 21 110 3.5E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 SUPERFAMILY SSF55781 78 263 1.11E-44 T 28-03-2018 IPR029016 GAF domain-like AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 Pfam PF09339 IclR helix-turn-helix domain 24 73 2.1E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 SUPERFAMILY SSF46785 21 92 5.07E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 Gene3D G3DSA:1.10.10.10 3 81 4.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14355 1771fdab2509cdeb300382a5c42e5e29 267 Pfam PF01614 Bacterial transcriptional regulator 139 254 9.2E-30 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 9.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 SUPERFAMILY SSF53850 96 287 2.35E-30 T 28-03-2018 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 Gene3D G3DSA:3.40.190.10 93 176 2.8E-11 T 28-03-2018 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 Gene3D G3DSA:1.10.10.10 5 91 2.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 SUPERFAMILY SSF46785 8 88 1.18E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 Pfam PF03466 LysR substrate binding domain 96 286 7.5E-28 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS06125 02901367b63b6531c7e668bd5352a9ee 290 Gene3D G3DSA:3.40.190.10 177 256 4.7E-15 T 28-03-2018 AFA_RS04380 a6163d96157bf24aa4ee9ea8c5e3fb01 414 TIGRFAM TIGR00843 benE: benzoate transporter 15 390 3.3E-117 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS04380 a6163d96157bf24aa4ee9ea8c5e3fb01 414 Pfam PF03594 Benzoate membrane transport protein 19 389 7.7E-134 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 Gene3D G3DSA:3.30.1190.10 108 164 9.1E-9 T 28-03-2018 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 Gene3D G3DSA:1.10.10.60 69 107 6.2E-11 T 28-03-2018 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 SMART SM00530 89 151 1.0E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 SUPERFAMILY SSF47413 90 122 1.49E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 Pfam PF00350 Dynamin family 197 368 3.1E-14 T 28-03-2018 IPR022812 Dynamin superfamily AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 Pfam PF01381 Helix-turn-helix 92 133 6.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 SUPERFAMILY SSF52540 189 247 5.76E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 SUPERFAMILY SSF52540 301 414 5.76E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09805 f05ec47f28de5b586e3439dbb533fee7 812 Gene3D G3DSA:3.40.50.300 174 583 1.5E-22 T 28-03-2018 AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 Gene3D G3DSA:3.90.1670.10 19 308 6.5E-88 T 28-03-2018 IPR024064 FdhE-like AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 Pfam PF04216 Protein involved in formate dehydrogenase formation 17 305 1.4E-103 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 304 3.7E-86 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 Hamap MF_00611 Protein FdhE [fdhE]. 2 307 33.434 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 PIRSF PIRSF018296 1 308 4.3E-93 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 AFA_RS16840 f92f27e3c0c98a3c0372166cb3cefe24 308 SUPERFAMILY SSF144020 22 306 5.1E-80 T 28-03-2018 IPR024064 FdhE-like AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 Gene3D G3DSA:1.10.10.60 2 58 8.2E-17 T 28-03-2018 AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 SUPERFAMILY SSF48498 84 189 8.9E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 SUPERFAMILY SSF46689 3 75 1.8E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 Gene3D G3DSA:1.10.357.10 59 190 6.2E-13 T 28-03-2018 AFA_RS12070 538d2b5fe49afd38084de4071e510999 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 4.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00091 244 314 0.11 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00091 368 434 1.3E-5 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SUPERFAMILY SSF55785 374 480 7.85E-25 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Gene3D G3DSA:3.30.450.20 367 508 1.3E-26 T 28-03-2018 AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Pfam PF00990 Diguanylate cyclase, GGDEF domain 493 650 1.4E-52 T 28-03-2018 IPR000160 GGDEF domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00086 440 482 67.0 T 28-03-2018 IPR001610 PAC motif AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00086 320 360 0.43 T 28-03-2018 IPR001610 PAC motif AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 374 488 1.4E-16 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 248 364 1.9E-14 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Gene3D G3DSA:3.30.70.270 509 663 1.7E-62 T 28-03-2018 AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Gene3D G3DSA:3.20.20.450 664 925 9.6E-93 T 28-03-2018 IPR001633 EAL domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00267 482 654 9.5E-67 T 28-03-2018 IPR000160 GGDEF domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SUPERFAMILY SSF55073 498 654 6.04E-52 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Gene3D G3DSA:3.30.450.20 227 365 4.1E-13 T 28-03-2018 AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SUPERFAMILY SSF141868 670 921 4.32E-84 T 28-03-2018 IPR001633 EAL domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SUPERFAMILY SSF55785 262 364 1.22E-13 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Pfam PF13426 PAS domain 261 359 3.5E-6 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Pfam PF13426 PAS domain 380 480 5.1E-14 T 28-03-2018 IPR000014 PAS domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 491 651 5.3E-46 T 28-03-2018 IPR000160 GGDEF domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 Pfam PF00563 EAL domain 670 906 1.1E-67 T 28-03-2018 IPR001633 EAL domain AFA_RS03195 1a0a81427d55dd6181f08091887fd096 942 SMART SM00052 664 911 1.7E-101 T 28-03-2018 IPR001633 EAL domain AFA_RS03215 f4b04643d5e02af1f04ae0825e3d391c 331 Gene3D G3DSA:3.40.50.300 119 326 4.8E-29 T 28-03-2018 AFA_RS03215 f4b04643d5e02af1f04ae0825e3d391c 331 Pfam PF02562 PhoH-like protein 123 326 2.4E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 AFA_RS03215 f4b04643d5e02af1f04ae0825e3d391c 331 SUPERFAMILY SSF52540 79 303 3.25E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 136 365 1.1E-68 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 10 132 3.4E-33 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 Gene3D G3DSA:3.40.50.720 1 164 7.2E-35 T 28-03-2018 AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 SMART SM01002 141 310 1.5E-81 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 SMART SM01003 4 132 3.4E-47 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 SUPERFAMILY SSF52283 1 163 5.19E-40 T 28-03-2018 AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 Gene3D G3DSA:3.40.50.720 181 370 4.2E-37 T 28-03-2018 AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 165 190 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 AFA_RS04635 3df726efa946eb4af27147e9051a032f 372 SUPERFAMILY SSF51735 132 315 3.08E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 SUPERFAMILY SSF50677 200 410 6.17E-47 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Gene3D G3DSA:3.90.740.10 191 402 4.4E-58 T 28-03-2018 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Pfam PF08264 Anticodon-binding domain of tRNA 705 860 2.4E-23 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Gene3D G3DSA:3.40.50.620 403 650 6.1E-71 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Gene3D G3DSA:3.30.2320.20 829 910 1.6E-19 T 28-03-2018 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 862 2.8E-264 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 660 6.5E-194 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Gene3D G3DSA:1.10.730.10 651 828 1.7E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.5E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 1.5E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 538 551 1.5E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 581 590 1.5E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 233 256 1.5E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 937 20.694 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 SUPERFAMILY SSF52374 1 198 1.05E-134 T 28-03-2018 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 SUPERFAMILY SSF52374 410 669 1.05E-134 T 28-03-2018 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Gene3D G3DSA:3.40.50.620 28 175 3.8E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 SUPERFAMILY SSF47323 672 936 6.35E-68 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS07510 dcab384b79518508794aec3d9d6b8b33 946 Pfam PF06827 Zinc finger found in FPG and IleRS 908 934 7.5E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFA_RS17550 0781764bba7ac9ec520c7f8ccbde04f0 209 Gene3D G3DSA:3.40.30.10 53 204 8.0E-8 T 28-03-2018 AFA_RS17550 0781764bba7ac9ec520c7f8ccbde04f0 209 SUPERFAMILY SSF52833 66 205 1.48E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 SUPERFAMILY SSF46609 2 90 4.84E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 Gene3D G3DSA:1.10.287.990 20 89 6.6E-27 T 28-03-2018 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 88 1.4E-30 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PIRSF PIRSF000349 1 203 1.3E-77 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 6.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 6.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 6.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 6.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 6.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 SUPERFAMILY SSF54719 88 202 2.75E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS08310 4cd6f2d6f367cc9fee7677c564e5eb5f 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 196 1.2E-38 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 SMART SM00857 4 139 1.9E-61 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 Gene3D G3DSA:3.40.50.1390 2 107 9.5E-35 T 28-03-2018 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 Gene3D G3DSA:1.20.5.40 108 137 2.8E-18 T 28-03-2018 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 SUPERFAMILY SSF53041 3 139 7.19E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFA_RS14235 0ba7eae250da178349d6529403b10fe0 187 Pfam PF00239 Resolvase, N terminal domain 5 138 1.2E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 Pfam PF00005 ABC transporter 22 194 5.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 Pfam PF00005 ABC transporter 343 476 1.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 SMART SM00382 351 529 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 SMART SM00382 31 239 5.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 SUPERFAMILY SSF52540 305 533 1.15E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 Gene3D G3DSA:3.40.50.300 293 554 5.9E-61 T 28-03-2018 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 Gene3D G3DSA:3.40.50.300 12 292 1.1E-53 T 28-03-2018 AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 Pfam PF12848 ABC transporter 233 309 5.3E-13 T 28-03-2018 IPR032781 ABC-transporter extension domain AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 SUPERFAMILY SSF52540 13 239 2.49E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03535 42bde3d3263856051f7d90f4ccd8213e 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 556 2.0E-291 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Pfam PF11898 Domain of unknown function (DUF3418) 670 1259 8.4E-211 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Gene3D G3DSA:3.40.50.300 22 182 6.7E-31 T 28-03-2018 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 9 1258 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 580 656 5.4E-15 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Gene3D G3DSA:3.40.50.300 204 385 1.7E-44 T 28-03-2018 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Pfam PF00270 DEAD/DEAH box helicase 30 180 8.9E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Pfam PF04408 Helicase associated domain (HA2) 429 510 7.8E-20 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SUPERFAMILY SSF52540 617 641 6.77E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SUPERFAMILY SSF52540 20 524 6.77E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 Pfam PF00271 Helicase conserved C-terminal domain 247 366 6.2E-12 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SMART SM00487 21 210 9.1E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SMART SM00382 38 332 6.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SMART SM00490 265 366 9.3E-15 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS05360 44e87939ddca8abe3822bb0e14fc1fa2 1263 SMART SM00847 426 516 9.3E-34 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 SUPERFAMILY SSF56935 132 844 1.72E-120 T 28-03-2018 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 174 843 5.1E-96 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 Pfam PF00593 TonB dependent receptor 353 842 1.3E-44 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 Pfam PF07660 Secretin and TonB N terminus short domain 88 125 1.3E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 Pfam PF07715 TonB-dependent Receptor Plug Domain 171 267 5.3E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 SMART SM00965 81 130 2.3E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 Gene3D G3DSA:2.40.170.20 284 843 4.2E-84 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS17465 791961b348fa145f4109e6ac6de90ed3 844 Gene3D G3DSA:2.170.130.10 130 283 5.9E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 9.3E-52 T 28-03-2018 AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 Gene3D G3DSA:3.40.50.720 1 259 4.0E-57 T 28-03-2018 AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 3.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 3.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09115 ed896675c353cabbdda4fe99b4b7637f 260 SUPERFAMILY SSF51735 12 256 1.85E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 Pfam PF00120 Glutamine synthetase, catalytic domain 104 467 7.5E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 Gene3D G3DSA:3.10.20.70 3 105 2.2E-27 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 SUPERFAMILY SSF54368 4 98 3.4E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 3.2E-193 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 Gene3D G3DSA:3.30.590.10 106 459 1.0E-119 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 SUPERFAMILY SSF55931 103 469 3.24E-136 T 28-03-2018 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 SMART SM01230 103 380 4.1E-142 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS09300 e288c2b521a6d367a5cbe7877d98e16d 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 96 3.4E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFA_RS05640 f25ee857a742dcb912bf76d40ba81754 407 Pfam PF12536 Patatin phospholipase 279 384 4.2E-36 T 28-03-2018 IPR021095 Protein of unknown function DUF3734 AFA_RS05640 f25ee857a742dcb912bf76d40ba81754 407 Gene3D G3DSA:3.40.1090.10 18 305 3.6E-42 T 28-03-2018 AFA_RS05640 f25ee857a742dcb912bf76d40ba81754 407 Pfam PF01734 Patatin-like phospholipase 29 242 5.4E-25 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFA_RS05640 f25ee857a742dcb912bf76d40ba81754 407 SUPERFAMILY SSF52151 148 373 4.01E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS05640 f25ee857a742dcb912bf76d40ba81754 407 SUPERFAMILY SSF52151 26 98 4.01E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 SUPERFAMILY SSF48179 183 332 7.48E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 4.0E-74 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.3E-63 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 4.4E-134 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 SUPERFAMILY SSF51735 1 182 8.79E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 Gene3D G3DSA:3.40.50.720 38 179 5.1E-55 T 28-03-2018 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 Gene3D G3DSA:1.10.1040.10 180 338 6.7E-56 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 PIRSF PIRSF000116 201 332 3.4E-13 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 PIRSF PIRSF000116 2 205 1.3E-45 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS13480 7bc80c77740c3831cead331824a02fce 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.609 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Pfam PF12804 MobA-like NTP transferase domain 5 249 5.8E-23 T 28-03-2018 IPR025877 MobA-like NTP transferase AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 454 1.8E-192 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 427 2.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 299 4.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 1.3E-4 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Gene3D G3DSA:2.160.10.10 245 309 9.1E-14 T 28-03-2018 AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 452 42.76 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 SUPERFAMILY SSF53448 2 252 2.29E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 SUPERFAMILY SSF51161 255 436 8.73E-49 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Gene3D G3DSA:3.90.550.10 2 244 8.6E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS17505 7ad8af3a973aadd751a80f14e4a63bc0 456 Gene3D G3DSA:2.160.10.10 310 438 6.4E-33 T 28-03-2018 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 195 1.0E-40 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 SUPERFAMILY SSF48179 199 311 1.11E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 299 9.5E-22 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 SUPERFAMILY SSF51735 6 196 2.15E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 Gene3D G3DSA:1.10.1040.10 199 304 1.5E-24 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 Gene3D G3DSA:3.40.50.720 1 198 1.8E-36 T 28-03-2018 AFA_RS01510 6b26276d950043b5ae67e6e88ee8ca0a 338 PIRSF PIRSF000105 2 325 7.2E-73 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 SUPERFAMILY SSF56176 427 518 1.8E-19 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 Gene3D G3DSA:3.10.580.10 280 427 8.8E-21 T 28-03-2018 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 SMART SM01091 430 515 6.5E-23 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 Pfam PF03741 Integral membrane protein TerC family 14 203 2.1E-44 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 Gene3D G3DSA:3.30.465.10 428 515 7.1E-22 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 Pfam PF03471 Transporter associated domain 431 514 3.3E-21 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 SUPERFAMILY SSF54631 286 420 5.86E-21 T 28-03-2018 AFA_RS04525 628f32bb7cf0d763b5c2ca57be24c9cc 527 Pfam PF00571 CBS domain 368 417 4.0E-5 T 28-03-2018 IPR000644 CBS domain AFA_RS10020 b91bf0feb5f25480610f4e4f4618b247 187 Pfam PF04264 YceI-like domain 30 185 5.2E-29 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10020 b91bf0feb5f25480610f4e4f4618b247 187 SMART SM00867 27 187 1.4E-37 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10020 b91bf0feb5f25480610f4e4f4618b247 187 Gene3D G3DSA:2.40.128.110 26 187 3.3E-38 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10020 b91bf0feb5f25480610f4e4f4618b247 187 SUPERFAMILY SSF101874 30 186 1.2E-36 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 107 224 1.2E-26 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 7 227 16.67 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 Gene3D G3DSA:1.25.40.10 108 228 1.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 Pfam PF13525 Outer membrane lipoprotein 105 227 1.7E-8 T 28-03-2018 AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 Gene3D G3DSA:1.20.58.130 23 82 2.1E-4 T 28-03-2018 AFA_RS14640 5b8daa7b768e5816defae3d919a7318a 228 SUPERFAMILY SSF48452 108 223 8.78E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 198 268 1.7E-4 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 SMART SM00342 101 184 2.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Gene3D G3DSA:1.10.10.60 140 184 0.0045 T 28-03-2018 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 322 328 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 SUPERFAMILY SSF46767 271 352 4.05E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 272 351 2.5E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Gene3D G3DSA:3.30.160.70 185 267 1.0E-19 T 28-03-2018 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Pfam PF02805 Metal binding domain of Ada 12 74 6.5E-27 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Gene3D G3DSA:3.40.10.10 2 78 3.3E-22 T 28-03-2018 IPR035451 Ada-like domain AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Gene3D G3DSA:1.10.10.10 268 353 7.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 273 351 3.3E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Pfam PF12833 Helix-turn-helix domain 107 185 1.2E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 SUPERFAMILY SSF46689 87 133 1.21E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 SUPERFAMILY SSF53155 191 269 6.08E-22 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 SUPERFAMILY SSF57884 6 93 1.7E-25 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 PIRSF PIRSF000409 1 354 1.3E-136 T 28-03-2018 IPR016221 Bifunctional regulatory protein Ada AFA_RS02940 20d427cebaa7471b5d030812cf0a95f7 354 Gene3D G3DSA:1.10.10.60 81 139 6.3E-16 T 28-03-2018 AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 PIRSF PIRSF006293 6 243 2.1E-66 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 Gene3D G3DSA:3.40.50.620 7 243 3.4E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 SUPERFAMILY SSF52402 9 239 1.85E-52 T 28-03-2018 AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 10 226 3.6E-58 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 8 239 47.936 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFA_RS14055 7144cbc5911537eb501da425de3920a7 243 Pfam PF06508 Queuosine biosynthesis protein QueC 9 233 2.4E-70 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Gene3D G3DSA:3.40.50.300 287 386 4.3E-26 T 28-03-2018 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Gene3D G3DSA:3.40.50.300 10 158 3.9E-27 T 28-03-2018 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Gene3D G3DSA:3.40.50.300 159 286 5.9E-28 T 28-03-2018 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Pfam PF00580 UvrD/REP helicase N-terminal domain 16 275 2.7E-69 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Pfam PF13361 UvrD-like helicase C-terminal domain 281 639 4.9E-60 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Gene3D G3DSA:1.10.486.10 387 566 2.5E-36 T 28-03-2018 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 14 689 37.45 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 AFA_RS01750 6664059031a03b906f7968f25d59f03e 691 SUPERFAMILY SSF52540 13 659 3.85E-155 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 149 1.7E-55 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 106 123 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 Pfam PF00364 Biotin-requiring enzyme 76 149 4.3E-25 T 28-03-2018 IPR000089 Biotin/lipoyl attachment AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 Gene3D G3DSA:2.40.50.100 107 150 6.4E-19 T 28-03-2018 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 SUPERFAMILY SSF51230 75 149 1.3E-25 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 Gene3D G3DSA:3.90.1170.30 21 106 3.0E-4 T 28-03-2018 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 96 110 1.0E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 79 92 1.0E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFA_RS15650 b97d21cae251a6b13b1a8858c564263c 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 111 124 1.0E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFA_RS09325 354df8cc84b1771a9905494a654165e1 262 Pfam PF00005 ABC transporter 25 168 4.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS09325 354df8cc84b1771a9905494a654165e1 262 SMART SM00382 33 218 8.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09325 354df8cc84b1771a9905494a654165e1 262 SUPERFAMILY SSF52540 5 245 3.82E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09325 354df8cc84b1771a9905494a654165e1 262 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS09325 354df8cc84b1771a9905494a654165e1 262 Gene3D G3DSA:3.40.50.300 1 257 4.8E-70 T 28-03-2018 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 SUPERFAMILY SSF55347 155 317 7.74E-69 T 28-03-2018 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 3.0E-63 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 1.2E-35 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PIRSF PIRSF000149 1 337 6.0E-132 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 Gene3D G3DSA:3.40.50.720 1 164 2.7E-70 T 28-03-2018 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 SMART SM00846 3 155 6.4E-88 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 Gene3D G3DSA:3.30.360.10 165 318 6.1E-63 T 28-03-2018 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 5.6E-126 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 SUPERFAMILY SSF51735 1 154 5.43E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 5.5E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 5.5E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 5.5E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 5.5E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03390 8a24a03e765c4eb49b064119bb507811 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 5.5E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 Gene3D G3DSA:3.30.70.20 161 238 7.3E-24 T 28-03-2018 AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 Pfam PF13247 4Fe-4S dicluster domain 101 195 5.7E-29 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 Gene3D G3DSA:3.30.70.20 10 63 0.003 T 28-03-2018 AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 Gene3D G3DSA:3.30.70.20 122 160 4.1E-20 T 28-03-2018 AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 SUPERFAMILY SSF54862 51 230 1.15E-67 T 28-03-2018 AFA_RS09190 1d3fd32e82f28b6e864c90fe879e2dc9 252 Gene3D G3DSA:3.30.70.20 64 121 2.4E-17 T 28-03-2018 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 552 1059 1.4E-223 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 88 200 2.0E-43 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 SUPERFAMILY SSF53720 607 1058 3.53E-123 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 857 868 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 SUPERFAMILY SSF81935 28 202 1.11E-60 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Pfam PF00171 Aldehyde dehydrogenase family 609 1053 6.3E-113 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Gene3D G3DSA:1.20.5.550 29 77 1.4E-14 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Gene3D G3DSA:3.40.309.10 849 1042 2.4E-47 T 28-03-2018 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Pfam PF01619 Proline dehydrogenase 210 511 3.3E-98 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Gene3D G3DSA:3.20.20.220 127 552 5.3E-107 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 Gene3D G3DSA:3.40.605.10 585 848 3.4E-67 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 SUPERFAMILY SSF51730 203 559 2.86E-118 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS13860 6946500aa324b548969d41c7cf6c164c 1261 PIRSF PIRSF000197 16 1261 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Gene3D G3DSA:3.40.50.970 373 590 1.3E-39 T 28-03-2018 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 SUPERFAMILY SSF52467 194 378 1.45E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Gene3D G3DSA:3.40.50.970 12 193 7.2E-45 T 28-03-2018 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 424 574 5.6E-36 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 SUPERFAMILY SSF52518 402 600 7.32E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 182 1.0E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 16 600 0.0 T 28-03-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Gene3D G3DSA:3.40.50.1220 196 372 2.2E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 339 3.2E-36 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFA_RS10690 e6d8b8fbf10f197fdcb35d2093a7dd83 604 SUPERFAMILY SSF52518 16 189 3.73E-44 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS00195 1def604149c36e7839efe153124edcd8 292 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 255 1.6E-70 T 28-03-2018 AFA_RS00195 1def604149c36e7839efe153124edcd8 292 SUPERFAMILY SSF51621 5 291 4.26E-76 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS00195 1def604149c36e7839efe153124edcd8 292 Gene3D G3DSA:3.20.20.60 1 290 5.0E-67 T 28-03-2018 AFA_RS00195 1def604149c36e7839efe153124edcd8 292 TIGRFAM TIGR02321 Pphn_pyruv_hyd: phosphonopyruvate hydrolase 5 292 1.9E-169 T 28-03-2018 IPR012649 Phosphonopyruvate hydrolase KEGG: 00440+3.11.1.3 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 Pfam PF03441 FAD binding domain of DNA photolyase 274 470 1.8E-86 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 SUPERFAMILY SSF48173 199 475 9.94E-106 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 PRINTS PR00147 DNA photolyase signature 149 165 2.9E-30 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 PRINTS PR00147 DNA photolyase signature 382 396 2.9E-30 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 PRINTS PR00147 DNA photolyase signature 323 339 2.9E-30 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 PRINTS PR00147 DNA photolyase signature 343 361 2.9E-30 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 Pfam PF00875 DNA photolyase 13 169 2.7E-49 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 SUPERFAMILY SSF52425 11 175 5.76E-55 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 343 362 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 Gene3D G3DSA:1.10.579.10 292 474 3.4E-77 T 28-03-2018 AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 323 335 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 Gene3D G3DSA:3.40.50.620 10 137 9.3E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS14475 fd11bbbd75e7ef99d56cd568e3f45caf 479 Gene3D G3DSA:1.25.40.80 138 291 4.8E-36 T 28-03-2018 AFA_RS10900 ed9571c1a05770bee3629fc2623ca3db 295 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 122 226 7.3E-25 T 28-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain AFA_RS10900 ed9571c1a05770bee3629fc2623ca3db 295 Gene3D G3DSA:3.90.1210.10 48 129 3.1E-12 T 28-03-2018 AFA_RS10900 ed9571c1a05770bee3629fc2623ca3db 295 Pfam PF08666 SAF domain 55 115 3.1E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFA_RS10900 ed9571c1a05770bee3629fc2623ca3db 295 SMART SM00858 53 116 1.4E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFA_RS10900 ed9571c1a05770bee3629fc2623ca3db 295 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 19 266 7.0E-46 T 28-03-2018 IPR017592 Pilus assembly, Flp-type CpaB AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Gene3D G3DSA:3.40.50.300 2 74 5.1E-11 T 28-03-2018 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 SUPERFAMILY SSF52540 5 221 4.87E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 SUPERFAMILY SSF50447 207 303 6.48E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 8.4E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 SUPERFAMILY SSF50465 304 396 2.3E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.4E-228 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.999 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Gene3D G3DSA:3.40.50.300 75 205 2.1E-29 T 28-03-2018 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 7.9E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 5.4E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Gene3D G3DSA:2.40.30.10 302 395 1.4E-32 T 28-03-2018 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Gene3D G3DSA:2.40.30.10 208 301 1.5E-30 T 28-03-2018 AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS18290 3deef279923030942259ccba3ffd9fb4 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.8E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 Gene3D G3DSA:1.25.40.10 151 213 1.1E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 Gene3D G3DSA:1.25.40.10 117 150 2.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 Pfam PF13181 Tetratricopeptide repeat 139 169 0.069 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 SUPERFAMILY SSF48452 72 184 1.63E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 SMART SM00028 63 96 170.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 SMART SM00028 103 136 89.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 SMART SM00028 137 170 1.3E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS04545 dd16c1ea9ba33328f968b33cd78e0fa5 213 Gene3D G3DSA:1.25.40.10 23 116 1.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14780 56aa7fda0e4eafcbc363f4ce52e298e3 330 SUPERFAMILY SSF53659 23 317 2.59E-65 T 28-03-2018 AFA_RS14780 56aa7fda0e4eafcbc363f4ce52e298e3 330 Pfam PF01515 Phosphate acetyl/butaryl transferase 101 313 7.1E-40 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS14780 56aa7fda0e4eafcbc363f4ce52e298e3 330 Gene3D G3DSA:3.40.50.10750 136 290 3.1E-42 T 28-03-2018 AFA_RS14780 56aa7fda0e4eafcbc363f4ce52e298e3 330 Gene3D G3DSA:3.40.50.2300 5 111 7.9E-4 T 28-03-2018 AFA_RS14780 56aa7fda0e4eafcbc363f4ce52e298e3 330 PIRSF PIRSF000428 19 319 1.5E-82 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS13200 f90101129b1c02a544570cade063296a 172 Pfam PF03358 NADPH-dependent FMN reductase 21 122 8.8E-6 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS13200 f90101129b1c02a544570cade063296a 172 Gene3D G3DSA:3.40.50.360 4 171 1.8E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS13200 f90101129b1c02a544570cade063296a 172 SUPERFAMILY SSF52218 9 170 5.2E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 Gene3D G3DSA:3.40.1160.10 1 298 6.5E-71 T 28-03-2018 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 272 2.1E-73 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 PRINTS PR00474 Glutamate 5-kinase family signature 247 267 1.2E-6 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 PRINTS PR00474 Glutamate 5-kinase family signature 62 76 1.2E-6 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 PRINTS PR00474 Glutamate 5-kinase family signature 197 224 1.2E-6 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 Pfam PF00696 Amino acid kinase family 31 274 2.1E-45 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 PIRSF PIRSF000728 16 297 2.5E-102 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 SUPERFAMILY SSF53633 11 297 1.96E-88 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS16400 3638342ee6c42f5694ab5c3d0066eb9c 298 Hamap MF_00082_B Acetylglutamate kinase [argB]. 29 297 35.377 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:3.40.50.10660 97 174 4.1E-15 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Pfam PF00989 PAS fold 202 265 2.2E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:3.40.50.300 324 502 1.7E-23 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:1.20.5.170 175 200 0.0058 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Pfam PF06506 Propionate catabolism activator 34 196 3.9E-42 T 28-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 198 266 3.8E-6 T 28-03-2018 IPR000014 PAS domain AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:1.10.8.60 503 577 2.5E-17 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 546 555 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SMART SM00382 349 494 5.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:3.30.450.20 201 310 3.1E-14 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Pfam PF02954 Bacterial regulatory protein, Fis family 598 636 5.1E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 603 620 1.6E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 620 637 1.6E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Pfam PF00158 Sigma-54 interaction domain 329 495 2.0E-65 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:3.40.50.2300 6 96 1.6E-11 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SUPERFAMILY SSF52540 328 563 3.77E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 14 635 3.7E-171 T 28-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SUPERFAMILY SSF159800 13 192 6.15E-39 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SUPERFAMILY SSF55785 200 294 1.24E-12 T 28-03-2018 IPR000014 PAS domain AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 Gene3D G3DSA:1.10.10.60 578 637 3.1E-15 T 28-03-2018 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SUPERFAMILY SSF46689 546 636 8.6E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 SMART SM00091 201 267 7.7E-9 T 28-03-2018 IPR000014 PAS domain AFA_RS04820 d65a79ca8e6d5491b08ad3ed382a3538 637 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 416 431 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 SUPERFAMILY SSF56281 14 270 4.98E-64 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 Pfam PF00753 Metallo-beta-lactamase superfamily 26 182 7.8E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 16 270 1.4E-101 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 13 270 42.99 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 PIRSF PIRSF005457 10 270 1.1E-97 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 Gene3D G3DSA:3.60.15.10 9 270 8.2E-67 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 183 270 8.5E-27 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFA_RS15205 c030b6e0db65cbbb9571a46be5b73a3e 270 SMART SM00849 23 182 5.5E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SUPERFAMILY SSF51735 225 384 8.23E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SMART SM00997 225 384 1.5E-114 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 77 91 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SMART SM00996 5 464 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 PIRSF PIRSF001109 1 465 1.1E-189 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 6 457 6.5E-187 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 225 384 5.9E-81 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 5 464 6.6E-146 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 Gene3D G3DSA:3.40.50.1480 243 438 1.7E-83 T 28-03-2018 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 Gene3D G3DSA:3.40.50.1480 1 242 5.6E-89 T 28-03-2018 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 457 48.731 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SUPERFAMILY SSF52283 177 224 7.94E-113 T 28-03-2018 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SUPERFAMILY SSF52283 385 465 7.94E-113 T 28-03-2018 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 SUPERFAMILY SSF52283 2 141 7.94E-113 T 28-03-2018 AFA_RS02025 c448796f602a55f6cb586543a2b9fef7 465 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 247 263 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFA_RS06235 8d1124fe5e5d3bbfabca5eaa4b9dd45f 108 SUPERFAMILY SSF81296 9 104 9.24E-26 T 28-03-2018 IPR014756 Immunoglobulin E-set AFA_RS06235 8d1124fe5e5d3bbfabca5eaa4b9dd45f 108 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 13 102 2.0E-25 T 28-03-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ AFA_RS06235 8d1124fe5e5d3bbfabca5eaa4b9dd45f 108 Gene3D G3DSA:2.60.40.10 4 104 2.0E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS06235 8d1124fe5e5d3bbfabca5eaa4b9dd45f 108 Pfam PF08770 Sulphur oxidation protein SoxZ 13 101 9.6E-27 T 28-03-2018 IPR014880 Sulphur oxidation protein SoxZ AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 Gene3D G3DSA:3.40.190.10 83 182 7.0E-9 T 28-03-2018 AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 Pfam PF03466 LysR substrate binding domain 89 301 4.0E-20 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 Gene3D G3DSA:3.40.190.10 183 272 1.5E-8 T 28-03-2018 AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 SUPERFAMILY SSF46785 4 86 2.99E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 Gene3D G3DSA:1.10.10.10 2 82 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09085 e0e315f062a157c393909ffab42a2c65 304 SUPERFAMILY SSF53850 88 300 1.3E-18 T 28-03-2018 AFA_RS00905 28f0a40a89fa8f1ffaa99c37bc5adf3d 431 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 159 366 1.0E-4 T 28-03-2018 AFA_RS00905 28f0a40a89fa8f1ffaa99c37bc5adf3d 431 PIRSF PIRSF006066 5 431 3.3E-93 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00905 28f0a40a89fa8f1ffaa99c37bc5adf3d 431 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 423 1.7E-88 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00905 28f0a40a89fa8f1ffaa99c37bc5adf3d 431 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 7.3E-115 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 13 394 39.515 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PIRSF PIRSF000724 3 396 7.8E-137 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 16 32 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 37 59 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.8E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 Gene3D G3DSA:3.40.50.1260 5 180 9.0E-58 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 Gene3D G3DSA:3.40.50.1260 181 382 5.2E-79 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 Pfam PF00162 Phosphoglycerate kinase 17 384 3.1E-140 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 SUPERFAMILY SSF53748 16 395 1.18E-142 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS03395 89712d6aca68b9966a0bb795a48ea4bf 396 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 21 31 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS10310 0589023bb197fb2501e282ef058090be 117 Gene3D G3DSA:1.10.10.10 3 114 2.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10310 0589023bb197fb2501e282ef058090be 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 1.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS10310 0589023bb197fb2501e282ef058090be 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 1.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS10310 0589023bb197fb2501e282ef058090be 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 1.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS10310 0589023bb197fb2501e282ef058090be 117 SUPERFAMILY SSF46785 3 91 2.55E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10310 0589023bb197fb2501e282ef058090be 117 SMART SM00418 15 92 2.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS10310 0589023bb197fb2501e282ef058090be 117 Pfam PF12840 Helix-turn-helix domain 15 72 6.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 Pfam PF01047 MarR family 68 125 3.5E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 SMART SM00347 61 161 1.7E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 137 6.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 6.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 117 6.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 151 171 6.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 Gene3D G3DSA:1.10.10.10 4 181 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15140 c995b12224d30e2a21789023697c24e1 186 SUPERFAMILY SSF46785 41 178 8.47E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 Gene3D G3DSA:3.40.50.720 1 191 9.4E-23 T 28-03-2018 AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 SUPERFAMILY SSF51735 1 175 6.73E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 Gene3D G3DSA:1.10.1040.10 192 345 6.2E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 SUPERFAMILY SSF48179 184 355 3.74E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 182 326 1.5E-25 T 28-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 AFA_RS01515 16e756d2d8ac56332502b566176aa537 360 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 100 2.4E-5 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Pfam PF03704 Bacterial transcriptional activator domain 129 243 4.3E-15 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF48452 1107 1181 3.61E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF48452 908 1026 3.61E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Gene3D G3DSA:1.25.40.10 180 302 3.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SMART SM00028 815 848 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SMART SM00028 940 973 88.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SMART SM00028 1149 1182 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SMART SM00028 198 231 95.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SMART SM01043 109 246 2.1E-17 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Gene3D G3DSA:1.10.10.10 701 806 0.4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF52540 433 508 1.74E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF52540 568 684 1.74E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF48452 148 249 1.06E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF48452 71 100 1.06E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Gene3D G3DSA:3.40.50.300 437 676 1.3E-7 T 28-03-2018 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Gene3D G3DSA:1.10.10.10 4 106 1.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Pfam PF13191 AAA ATPase domain 436 620 3.8E-14 T 28-03-2018 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 SUPERFAMILY SSF46894 13 90 5.1E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS15045 e80553fc8806aeaaf3f183f6326b93e9 1203 Gene3D G3DSA:1.25.40.10 808 1202 8.7E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 PIRSF PIRSF006092 26 184 5.3E-43 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Gene3D G3DSA:1.10.287.180 29 101 9.0E-27 T 28-03-2018 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 146 162 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 43 74 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Gene3D G3DSA:3.10.50.30 104 190 4.5E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Pfam PF03449 Transcription elongation factor, N-terminal 30 100 1.1E-23 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 SUPERFAMILY SSF46557 29 103 4.05E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Hamap MF_00930 Transcription elongation factor GreB [greB]. 27 183 50.398 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 108 182 5.0E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 Hamap MF_00105 Transcription elongation factor GreA [greA]. 28 181 27.215 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 SUPERFAMILY SSF54534 107 182 1.7E-20 T 28-03-2018 AFA_RS07820 da024f8ee25a6031bad1633fd65a6d41 197 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 28 183 9.6E-66 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 Gene3D G3DSA:3.30.420.40 199 365 5.9E-23 T 28-03-2018 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 Gene3D G3DSA:3.30.420.40 3 176 2.6E-50 T 28-03-2018 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 5 365 1.3E-134 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 4 365 38.611 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 SUPERFAMILY SSF53067 6 39 4.4E-20 T 28-03-2018 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 SUPERFAMILY SSF53067 139 339 4.4E-20 T 28-03-2018 AFA_RS15500 9e6bc56a2bb74a1fcf0992d1ff149b6b 365 SUPERFAMILY SSF53067 66 109 4.4E-20 T 28-03-2018 AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 SUPERFAMILY SSF54423 35 88 6.08E-9 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 Gene3D G3DSA:3.40.30.10 108 243 6.0E-22 T 28-03-2018 AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 Gene3D G3DSA:3.10.450.70 30 89 6.2E-15 T 28-03-2018 AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 SUPERFAMILY SSF52833 97 239 3.39E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 Pfam PF13098 Thioredoxin-like domain 118 236 1.1E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 Pfam PF10411 Disulfide bond isomerase protein N-terminus 36 89 1.4E-15 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AFA_RS01395 9953627e7f4e9ab8f18686773516b9b9 243 ProSitePatterns PS00194 Thioredoxin family active site. 125 143 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 Pfam PF16234 Domain of unknown function (DUF4892) 25 212 1.8E-12 T 28-03-2018 IPR032608 Protein of unknown function DUF4892 AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 PRINTS PR01021 OMPA domain signature 248 263 4.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 PRINTS PR01021 OMPA domain signature 218 240 4.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 PRINTS PR01021 OMPA domain signature 263 279 4.9E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 SUPERFAMILY SSF103088 206 319 3.4E-32 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 Gene3D G3DSA:3.30.1330.60 168 320 1.6E-35 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS09875 20ac88e6b5cb6e4d18781157f4b85234 320 Pfam PF00691 OmpA family 217 313 8.1E-20 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS08955 28e9f518f8295ae643a8179048f18f0c 436 Pfam PF08857 Putative ParB-like nuclease 74 302 5.4E-52 T 28-03-2018 IPR014956 Putative ParB-like nuclease AFA_RS08955 28e9f518f8295ae643a8179048f18f0c 436 Gene3D G3DSA:1.10.8.10 271 359 2.1E-13 T 28-03-2018 AFA_RS08955 28e9f518f8295ae643a8179048f18f0c 436 SUPERFAMILY SSF110849 70 135 5.75E-48 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS08955 28e9f518f8295ae643a8179048f18f0c 436 SUPERFAMILY SSF110849 174 309 5.75E-48 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS08955 28e9f518f8295ae643a8179048f18f0c 436 Gene3D G3DSA:3.90.1530.10 68 260 1.5E-43 T 28-03-2018 AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 SUPERFAMILY SSF117143 92 223 1.44E-33 T 28-03-2018 AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 1.3E-112 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 148 244 1.5E-28 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 9.0E-49 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 Pfam PF00460 Flagella basal body rod protein 5 35 7.7E-15 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS05845 d90573f57fbffd63ecef3125c72ef1b1 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 261 8.2E-23 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 318 43.834 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 Pfam PF01207 Dihydrouridine synthase (Dus) 6 303 1.3E-72 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 PIRSF PIRSF006621 1 302 3.0E-69 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 SUPERFAMILY SSF51395 3 299 1.1E-66 T 28-03-2018 AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 Gene3D G3DSA:3.20.20.70 2 241 3.9E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS10860 2cb8bcd072e58fa4999d0652cff2c099 320 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 85 103 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 Gene3D G3DSA:2.60.130.10 2 295 5.9E-69 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 136 164 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 Pfam PF00775 Dioxygenase 105 293 8.8E-67 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 SUPERFAMILY SSF49482 4 294 2.09E-97 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 Pfam PF04444 Catechol dioxygenase N terminus 27 94 2.9E-24 T 28-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 AFA_RS08245 8267bf6c143603f9f1f8dd692202af1b 311 TIGRFAM TIGR02439 catechol_proteo: catechol 1,2-dioxygenase 7 292 2.3E-142 T 28-03-2018 IPR012801 Catechol 1,2-dioxygenase, proteobacteria GO:0005506|GO:0018576|GO:0019614|GO:0055114 KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Pfam PF00390 Malic enzyme, N-terminal domain 20 151 6.8E-26 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 SMART SM01274 18 151 6.1E-78 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Pfam PF03949 Malic enzyme, NAD binding domain 165 359 1.9E-17 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Gene3D G3DSA:3.40.50.10380 5 160 3.8E-34 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 SUPERFAMILY SSF51735 163 436 2.87E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 755 2.9E-92 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Gene3D G3DSA:3.40.50.720 161 450 6.0E-75 T 28-03-2018 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 Gene3D G3DSA:3.40.718.10 451 725 9.0E-52 T 28-03-2018 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 PIRSF PIRSF036684 1 763 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 SUPERFAMILY SSF53659 430 759 9.46E-86 T 28-03-2018 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 SUPERFAMILY SSF53223 11 161 2.3E-51 T 28-03-2018 AFA_RS03365 65f0f54d6130840805210831ba1f57f0 764 SMART SM00919 163 400 3.9E-125 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS05515 312d27b11d75e3c17b32202e29c5d2c8 130 Gene3D G3DSA:1.10.700.10 4 117 2.7E-49 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit AFA_RS05515 312d27b11d75e3c17b32202e29c5d2c8 130 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 27 112 4.2E-38 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit AFA_RS05515 312d27b11d75e3c17b32202e29c5d2c8 130 TIGRFAM TIGR02792 PCA_ligA: protocatechuate 4,5-dioxygenase, alpha subunit 7 123 7.4E-68 T 28-03-2018 IPR014159 Protocatechuate 4,5-dioxygenase, alpha subunit KEGG: 00362+1.13.11.8|KEGG: 00624+1.13.11.8|KEGG: 00627+1.13.11.8|MetaCyc: PWY-6216|MetaCyc: PWY-6217 AFA_RS05515 312d27b11d75e3c17b32202e29c5d2c8 130 SUPERFAMILY SSF48076 4 127 3.27E-52 T 28-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 Gene3D G3DSA:3.30.750.44 28 87 2.3E-12 T 28-03-2018 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 Gene3D G3DSA:3.90.226.10 163 436 1.0E-65 T 28-03-2018 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 SUPERFAMILY SSF50156 78 172 2.23E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 Gene3D G3DSA:2.30.42.10 88 162 2.4E-17 T 28-03-2018 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 SMART SM00245 162 371 1.6E-64 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 Pfam PF13180 PDZ domain 89 168 2.8E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 SUPERFAMILY SSF52096 25 107 1.09E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 SUPERFAMILY SSF52096 181 376 1.09E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 42 374 1.2E-94 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 SMART SM00228 89 160 6.3E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS16415 ca0524518f69c44f7ff34f58f50269b6 492 Pfam PF03572 Peptidase family S41 187 370 6.5E-53 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFA_RS17540 918e2b5176ae903d723168c442312279 68 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 4.0E-25 T 28-03-2018 IPR021313 Protein of unknown function DUF2909 AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 Pfam PF00155 Aminotransferase class I and II 147 451 4.6E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 Gene3D G3DSA:3.90.1150.10 374 469 6.0E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 Gene3D G3DSA:3.40.640.10 131 373 2.9E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 2.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 SUPERFAMILY SSF53383 96 468 1.17E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 Gene3D G3DSA:1.10.10.10 1 68 2.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 SUPERFAMILY SSF46785 2 69 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14170 c6304bccdaf9b88bbf244bfe9f86c266 474 SMART SM00345 7 66 1.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 Gene3D G3DSA:3.40.190.10 134 213 5.9E-13 T 28-03-2018 AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 SMART SM00062 33 254 4.4E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 SUPERFAMILY SSF53850 1 253 2.29E-66 T 28-03-2018 AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 252 3.7E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS08465 57cde0cc2a4180acc13ee7063fa535f7 269 Gene3D G3DSA:3.40.190.10 23 133 4.7E-34 T 28-03-2018 AFA_RS16115 a51430142091036daf8140f63ea14a00 232 SMART SM00873 59 209 4.4E-5 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFA_RS16115 a51430142091036daf8140f63ea14a00 232 SUPERFAMILY SSF56037 53 190 3.92E-27 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 AFA_RS16115 a51430142091036daf8140f63ea14a00 232 Pfam PF03483 B3/4 domain 60 191 3.0E-17 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFA_RS16115 a51430142091036daf8140f63ea14a00 232 Gene3D G3DSA:3.50.40.10 58 205 1.5E-20 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 424 1.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16230 6786297102d2938009ec524e3a84843b 432 SUPERFAMILY SSF55785 85 193 5.71E-7 T 28-03-2018 IPR000014 PAS domain AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Gene3D G3DSA:1.10.287.130 198 265 2.1E-17 T 28-03-2018 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Pfam PF11808 Domain of unknown function (DUF3329) 8 84 3.6E-11 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Gene3D G3DSA:3.30.450.20 76 197 2.7E-9 T 28-03-2018 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 92 422 8.5E-117 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 SUPERFAMILY SSF47384 188 269 2.75E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 SUPERFAMILY SSF55874 260 424 1.18E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16230 6786297102d2938009ec524e3a84843b 432 SMART SM00387 313 426 2.9E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 269 6.7E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 Gene3D G3DSA:3.30.565.10 284 431 1.3E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16230 6786297102d2938009ec524e3a84843b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 4.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 4.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 4.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 4.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16230 6786297102d2938009ec524e3a84843b 432 SMART SM00388 201 270 2.5E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 287 319 140.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 197 229 240.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 113 144 16.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 152 184 0.0011 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 73 105 0.023 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SMART SM00564 328 360 80.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 SUPERFAMILY SSF50998 39 381 2.04E-61 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 14 391 34.729 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 Pfam PF13360 PQQ-like domain 88 318 4.4E-44 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 Gene3D G3DSA:2.140.10.10 234 390 4.8E-15 T 28-03-2018 AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 Gene3D G3DSA:2.140.10.10 126 233 1.4E-19 T 28-03-2018 AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 19 388 4.1E-115 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB AFA_RS11555 deb2134fc982e42d7ff326403df7d7d4 392 Gene3D G3DSA:2.130.10.10 45 125 0.12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 SUPERFAMILY SSF89550 8 264 2.75E-10 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Gene3D G3DSA:3.20.20.140 1 249 7.5E-33 T 28-03-2018 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Pfam PF01336 OB-fold nucleic acid binding domain 995 1071 1.4E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Pfam PF14579 Helix-hairpin-helix motif 806 904 8.4E-30 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Gene3D G3DSA:1.10.150.280 836 901 4.9E-11 T 28-03-2018 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 SMART SM00481 9 76 2.8E-20 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 294 733 1.8E-171 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Pfam PF02811 PHP domain 10 174 2.7E-40 T 28-03-2018 IPR004013 PHP domain GO:0003824 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 Gene3D G3DSA:2.40.50.140 977 1073 7.5E-14 T 28-03-2018 AFA_RS05365 494e4617a85200ed9315b02dd7e7fa06 1158 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 8 1030 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 SUPERFAMILY SSF56104 6 292 1.9E-103 T 28-03-2018 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 292 1.4E-81 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 Gene3D G3DSA:3.30.200.20 11 113 6.2E-35 T 28-03-2018 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 25.551 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 Gene3D G3DSA:3.30.470.20 114 249 6.3E-53 T 28-03-2018 AFA_RS03430 2f2d982ea2b8c6fe07598019f6bfd56b 293 Pfam PF01259 SAICAR synthetase 16 268 1.3E-103 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS09320 efe0fbc0718841c7761c9170f4560145 240 Pfam PF00462 Glutaredoxin 8 57 7.4E-6 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFA_RS09320 efe0fbc0718841c7761c9170f4560145 240 Gene3D G3DSA:3.40.30.10 4 75 1.1E-11 T 28-03-2018 AFA_RS09320 efe0fbc0718841c7761c9170f4560145 240 Pfam PF07291 Methylamine utilisation protein MauE 108 231 2.1E-4 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 AFA_RS09320 efe0fbc0718841c7761c9170f4560145 240 SUPERFAMILY SSF52833 6 68 2.51E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 7.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 7.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 215 257 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 Gene3D G3DSA:1.10.10.60 153 214 1.3E-8 T 28-03-2018 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 Pfam PF00072 Response regulator receiver domain 18 131 7.5E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 SMART SM00448 15 130 5.7E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 Pfam PF12833 Helix-turn-helix domain 184 262 1.5E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 SUPERFAMILY SSF46689 215 264 3.49E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 Gene3D G3DSA:3.40.50.2300 2 138 1.3E-15 T 28-03-2018 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 SMART SM00342 178 261 5.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 Gene3D G3DSA:1.10.10.60 215 277 1.1E-11 T 28-03-2018 AFA_RS02500 612bdccbe7e21a64297b84a2093c33ec 292 SUPERFAMILY SSF52172 11 138 2.7E-17 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 SUPERFAMILY SSF55347 124 233 1.18E-34 T 28-03-2018 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 PIRSF PIRSF000161 1 263 4.8E-85 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 1.5E-90 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 122 1.4E-39 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 6.0E-42 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 Gene3D G3DSA:3.40.50.720 1 118 1.8E-31 T 28-03-2018 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 34.155 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 SUPERFAMILY SSF51735 1 123 2.73E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 SUPERFAMILY SSF51735 233 263 2.73E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13790 2a674b981aa30ac0762ec4fce8faf714 263 Gene3D G3DSA:3.30.360.10 124 230 5.0E-32 T 28-03-2018 AFA_RS01610 4dca4834f47feeb67af1580b257606a1 145 Gene3D G3DSA:3.40.630.30 1 145 5.3E-26 T 28-03-2018 AFA_RS01610 4dca4834f47feeb67af1580b257606a1 145 Pfam PF13673 Acetyltransferase (GNAT) domain 48 130 2.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS01610 4dca4834f47feeb67af1580b257606a1 145 SUPERFAMILY SSF55729 1 142 5.23E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS12055 162b6344cf543d00c28d084afa054179 258 Gene3D G3DSA:1.25.40.290 149 258 2.1E-20 T 28-03-2018 AFA_RS12055 162b6344cf543d00c28d084afa054179 258 SUPERFAMILY SSF48371 88 255 5.85E-36 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 AFA_RS12055 162b6344cf543d00c28d084afa054179 258 Pfam PF08713 DNA alkylation repair enzyme 146 231 3.9E-8 T 28-03-2018 IPR014825 DNA alkylation repair enzyme AFA_RS12055 162b6344cf543d00c28d084afa054179 258 Gene3D G3DSA:1.25.40.70 35 143 0.0018 T 28-03-2018 AFA_RS04420 033c7e1bcfd15ecd44e0e6e64083aca6 254 SUPERFAMILY SSF100950 3 242 1.73E-81 T 28-03-2018 AFA_RS04420 033c7e1bcfd15ecd44e0e6e64083aca6 254 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 119 137 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 AFA_RS04420 033c7e1bcfd15ecd44e0e6e64083aca6 254 Gene3D G3DSA:3.40.50.1360 2 248 1.8E-69 T 28-03-2018 AFA_RS04420 033c7e1bcfd15ecd44e0e6e64083aca6 254 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 9 228 4.4E-20 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:1.20.1640.10 846 1030 4.3E-34 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82866 809 1030 6.8E-42 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82866 298 497 3.79E-48 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:3.30.70.1440 672 768 1.6E-15 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 7.2E-102 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82693 135 182 1.31E-22 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82693 274 330 1.31E-22 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82693 38 130 3.66E-24 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1037 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82714 724 808 1.57E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:3.30.70.1430 568 668 1.1E-18 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:3.30.70.1430 38 140 7.5E-25 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82714 182 272 1.07E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:3.30.2090.10 180 275 4.3E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:1.20.1640.10 286 510 2.8E-45 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Gene3D G3DSA:3.30.70.1320 769 845 2.8E-4 T 28-03-2018 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS10400 1d7aa58b8b12925014deb1c8d647510c 1064 SUPERFAMILY SSF82693 566 669 6.28E-27 T 28-03-2018 AFA_RS14800 e095c0a3b79d704fc7ff9af522a5c935 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 226 376 1.3E-42 T 28-03-2018 IPR000160 GGDEF domain AFA_RS14800 e095c0a3b79d704fc7ff9af522a5c935 382 SMART SM00267 213 380 7.9E-52 T 28-03-2018 IPR000160 GGDEF domain AFA_RS14800 e095c0a3b79d704fc7ff9af522a5c935 382 Gene3D G3DSA:3.30.70.270 221 382 1.5E-49 T 28-03-2018 AFA_RS14800 e095c0a3b79d704fc7ff9af522a5c935 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 379 5.9E-46 T 28-03-2018 IPR000160 GGDEF domain AFA_RS14800 e095c0a3b79d704fc7ff9af522a5c935 382 SUPERFAMILY SSF55073 229 379 1.49E-42 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 Gene3D G3DSA:1.10.260.40 41 70 9.9E-13 T 28-03-2018 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 Gene3D G3DSA:1.10.10.60 1 40 4.1E-16 T 28-03-2018 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 Gene3D G3DSA:1.10.357.10 71 197 1.1E-17 T 28-03-2018 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.0E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 SUPERFAMILY SSF48498 91 194 9.93E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS02345 fbaacddcfbff2e35661a4a6313aa8c72 202 SUPERFAMILY SSF46689 6 85 4.57E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 5.6E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Gene3D G3DSA:1.10.540.10 1 134 2.3E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Gene3D G3DSA:2.40.110.10 135 233 3.1E-29 T 28-03-2018 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 3.4E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 SUPERFAMILY SSF47203 247 394 1.53E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 SUPERFAMILY SSF56645 7 243 7.2E-74 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Gene3D G3DSA:1.20.140.10 234 397 1.0E-36 T 28-03-2018 AFA_RS03465 cae8836b5b2ad7e0fb20f029cd48bbd2 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 131 6.9E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS11520 e572571c71c5b3a8b3dfa44b3dcf5faf 385 PIRSF PIRSF001549 3 352 1.4E-33 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFA_RS11520 e572571c71c5b3a8b3dfa44b3dcf5faf 385 Gene3D G3DSA:3.30.930.10 16 317 1.5E-38 T 28-03-2018 AFA_RS11520 e572571c71c5b3a8b3dfa44b3dcf5faf 385 SUPERFAMILY SSF55681 4 318 1.27E-49 T 28-03-2018 AFA_RS11520 e572571c71c5b3a8b3dfa44b3dcf5faf 385 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 367 30.629 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFA_RS11520 e572571c71c5b3a8b3dfa44b3dcf5faf 385 Pfam PF13393 Histidyl-tRNA synthetase 10 316 2.6E-103 T 28-03-2018 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 5.0E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 224 234 5.0E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 5.0E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 286 297 5.0E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 5.0E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 Gene3D G3DSA:3.40.50.1370 168 308 1.9E-46 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 7.3E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 7.3E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 7.3E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 7.3E-28 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 SUPERFAMILY SSF53671 10 307 1.31E-103 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 308 76.872 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 307 2.9E-113 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 Gene3D G3DSA:3.40.50.1370 10 167 5.5E-64 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 305 1.0E-47 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 9.1E-51 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFA_RS07320 80ce9c7850b873912c87b2479afa1cb0 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS07835 f1089bde3fafacf0753ffee6bfb26b84 296 Gene3D G3DSA:3.40.50.1820 38 296 1.0E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07835 f1089bde3fafacf0753ffee6bfb26b84 296 Pfam PF12697 Alpha/beta hydrolase family 63 287 1.9E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS07835 f1089bde3fafacf0753ffee6bfb26b84 296 SUPERFAMILY SSF53474 53 294 8.44E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14835 daf4576e34a17e538ec1a9a043b400a1 420 SUPERFAMILY SSF89796 17 419 2.22E-142 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS14835 daf4576e34a17e538ec1a9a043b400a1 420 Pfam PF02515 CoA-transferase family III 20 398 1.1E-133 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS14835 daf4576e34a17e538ec1a9a043b400a1 420 Gene3D G3DSA:3.40.50.10540 14 420 1.1E-156 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 Pfam PF02637 GatB domain 332 483 5.2E-51 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 SUPERFAMILY SSF89095 301 406 3.92E-32 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 SMART SM00845 332 483 1.6E-78 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 Pfam PF02934 GatB/GatE catalytic domain 5 293 2.1E-108 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 SUPERFAMILY SSF55931 4 300 3.6E-116 T 28-03-2018 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 484 37.609 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 Gene3D G3DSA:1.10.10.410 423 484 2.5E-22 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFA_RS15890 00e6c83ec85772b8744a970ffaee30d4 485 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 483 3.9E-165 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 Gene3D G3DSA:1.20.1250.20 16 210 7.4E-29 T 28-03-2018 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 SUPERFAMILY SSF103473 2 205 2.09E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 SUPERFAMILY SSF103473 216 473 2.62E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 Pfam PF07690 Major Facilitator Superfamily 26 426 6.9E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 Gene3D G3DSA:1.20.1250.20 267 486 1.7E-22 T 28-03-2018 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 417 436 9.5E-8 T 28-03-2018 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 9.5E-8 T 28-03-2018 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 9.5E-8 T 28-03-2018 AFA_RS04825 32a65f1bab92670aa5e7d4e061c1c8d5 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 9.5E-8 T 28-03-2018 AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 SUPERFAMILY SSF53383 126 481 7.23E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 Gene3D G3DSA:3.40.640.10 152 358 3.2E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 Gene3D G3DSA:1.10.10.10 4 81 9.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 SUPERFAMILY SSF46785 10 83 7.68E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 Gene3D G3DSA:3.90.1150.10 359 486 2.0E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 SMART SM00345 20 79 9.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS11275 079e44e03bd06e68b5823331becd2a8e 490 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 9.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 Gene3D G3DSA:3.40.190.10 178 286 8.3E-23 T 28-03-2018 AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 PIRSF PIRSF002741 20 515 1.1E-92 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 Gene3D G3DSA:3.90.76.10 33 177 7.9E-36 T 28-03-2018 AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 71 92 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 439 3.6E-83 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 Gene3D G3DSA:3.10.105.10 287 493 1.2E-47 T 28-03-2018 AFA_RS00430 88fa1184d7e82ca92051dd9bc82863ad 523 SUPERFAMILY SSF53850 22 510 1.19E-127 T 28-03-2018 AFA_RS00465 96da2a606827ddaea7501d0d9992caae 108 Gene3D G3DSA:1.10.10.10 29 66 0.0041 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00465 96da2a606827ddaea7501d0d9992caae 108 SMART SM00530 52 106 1.5E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS00465 96da2a606827ddaea7501d0d9992caae 108 SUPERFAMILY SSF47413 53 106 1.85E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS00465 96da2a606827ddaea7501d0d9992caae 108 Pfam PF01381 Helix-turn-helix 53 106 3.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS00465 96da2a606827ddaea7501d0d9992caae 108 Gene3D G3DSA:1.10.260.40 67 107 3.2E-15 T 28-03-2018 AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 Gene3D G3DSA:3.30.1220.10 252 384 5.1E-31 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 Gene3D G3DSA:3.40.50.300 13 241 3.1E-53 T 28-03-2018 AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 269 383 6.8E-29 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 SMART SM00833 268 383 3.4E-54 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 SUPERFAMILY SSF52540 14 334 2.66E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08005 63bfa294781992b0bafefb4fc5a61fc8 407 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 17 221 3.6E-57 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 Gene3D G3DSA:3.40.250.10 1 156 6.2E-33 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 SUPERFAMILY SSF52821 4 147 4.06E-41 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 ProSitePatterns PS00380 Rhodanese signature 1. 39 50 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 Pfam PF00581 Rhodanese-like domain 161 274 3.4E-7 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 Pfam PF00581 Rhodanese-like domain 7 128 2.5E-20 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 SUPERFAMILY SSF52821 160 282 8.77E-29 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 Gene3D G3DSA:3.40.250.10 159 283 6.7E-19 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 SMART SM00450 6 132 3.5E-22 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS05170 e2a91835dab5ca9a2d6d4dda48232247 283 SMART SM00450 158 278 5.1E-5 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 2.2E-34 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 SUPERFAMILY SSF53901 5 325 1.65E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 Gene3D G3DSA:3.40.47.10 5 168 4.4E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 Gene3D G3DSA:3.40.47.10 169 325 7.4E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 324 2.1E-123 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 325 70.115 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS13120 e88c64d7a16027187a0a5df57248984c 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 190 4.6E-34 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS01550 0b922c7225a5ed9956424c524d67ab05 397 SUPERFAMILY SSF103473 4 384 6.41E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS01550 0b922c7225a5ed9956424c524d67ab05 397 Gene3D G3DSA:1.20.1250.20 196 394 3.5E-12 T 28-03-2018 AFA_RS01550 0b922c7225a5ed9956424c524d67ab05 397 Pfam PF07690 Major Facilitator Superfamily 11 347 2.5E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS01550 0b922c7225a5ed9956424c524d67ab05 397 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 379 3.0E-74 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AFA_RS01550 0b922c7225a5ed9956424c524d67ab05 397 Gene3D G3DSA:1.20.1250.20 2 190 1.0E-29 T 28-03-2018 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 Gene3D G3DSA:3.90.850.10 130 424 2.3E-84 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 SUPERFAMILY SSF56529 134 439 6.67E-91 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 138 436 1.5E-52 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 Gene3D G3DSA:2.30.30.230 16 126 1.4E-21 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 Pfam PF09298 Fumarylacetoacetase N-terminal 31 132 3.6E-17 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 SUPERFAMILY SSF63433 15 132 1.7E-24 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFA_RS02760 80f5862480cd79aed93122343ef462bd 441 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 16 439 4.6E-157 T 28-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 SUPERFAMILY SSF81648 290 332 1.57E-8 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 SUPERFAMILY SSF81342 16 288 3.14E-98 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 PIRSF PIRSF038885 4 338 4.6E-132 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 PIRSF PIRSF038885 343 461 6.7E-25 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 SUPERFAMILY SSF81648 355 446 8.76E-20 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 355 434 1.0E-28 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 329 2.7E-13 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 Gene3D G3DSA:1.20.810.10 344 453 6.6E-26 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 Gene3D G3DSA:1.20.810.10 15 338 6.0E-141 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 AFA_RS17215 552b08347c4631e8a4880b898f95f968 462 Pfam PF00033 Cytochrome b/b6/petB 31 219 1.2E-67 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 Gene3D G3DSA:3.40.190.10 97 187 1.5E-17 T 28-03-2018 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 2.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 Gene3D G3DSA:3.40.190.10 188 277 3.4E-20 T 28-03-2018 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 7.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 7.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 7.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 Gene3D G3DSA:1.10.10.10 5 90 1.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 SUPERFAMILY SSF53850 99 305 5.13E-34 T 28-03-2018 AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 SUPERFAMILY SSF46785 7 89 1.25E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03335 34cf9730d2507df274b6f106ad8c3e90 311 Pfam PF03466 LysR substrate binding domain 100 303 4.1E-32 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15355 d36bc3abed697fcf540dfbfecad59188 271 Gene3D G3DSA:1.10.3720.10 8 271 3.5E-24 T 28-03-2018 AFA_RS15355 d36bc3abed697fcf540dfbfecad59188 271 SUPERFAMILY SSF161098 71 260 1.02E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15355 d36bc3abed697fcf540dfbfecad59188 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 265 7.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15355 d36bc3abed697fcf540dfbfecad59188 271 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 20 265 2.0E-91 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 Pfam PF00005 ABC transporter 35 176 6.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 SUPERFAMILY SSF50331 252 374 3.8E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 SMART SM00382 43 232 4.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 SUPERFAMILY SSF52540 19 257 3.8E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 49 374 2.8E-121 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 Pfam PF08402 TOBE domain 294 374 1.0E-15 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 Gene3D G3DSA:2.40.50.140 297 366 0.0016 T 28-03-2018 AFA_RS05315 ccf63151b1923ef12d17003f605d16d1 376 Gene3D G3DSA:3.40.50.300 14 253 8.9E-71 T 28-03-2018 AFA_RS14985 e1355aaa62f3ca2de6fa702c72d3c0e3 256 Gene3D G3DSA:3.40.50.300 13 256 3.6E-55 T 28-03-2018 AFA_RS14985 e1355aaa62f3ca2de6fa702c72d3c0e3 256 Pfam PF00005 ABC transporter 37 184 6.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14985 e1355aaa62f3ca2de6fa702c72d3c0e3 256 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS14985 e1355aaa62f3ca2de6fa702c72d3c0e3 256 SMART SM00382 44 232 1.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14985 e1355aaa62f3ca2de6fa702c72d3c0e3 256 SUPERFAMILY SSF52540 19 253 1.04E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02675 a9c12fb951d739bad110bc7a1a9e4067 291 SUPERFAMILY SSF111364 27 291 8.11E-45 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 AFA_RS02675 a9c12fb951d739bad110bc7a1a9e4067 291 Gene3D G3DSA:2.40.230.20 20 286 5.5E-65 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 Gene3D G3DSA:3.40.190.10 179 274 9.3E-25 T 28-03-2018 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 SUPERFAMILY SSF46785 1 86 1.05E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.9E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 Gene3D G3DSA:3.40.190.10 88 178 1.0E-23 T 28-03-2018 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 SUPERFAMILY SSF53850 88 296 6.03E-40 T 28-03-2018 AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 Gene3D G3DSA:1.10.10.10 1 82 2.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09355 3b2e06ff121f720408244ad9e40ed686 321 Pfam PF03466 LysR substrate binding domain 87 294 3.7E-47 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 PIRSF PIRSF039144 1 112 8.3E-53 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.1E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 SUPERFAMILY SSF54913 1 112 2.07E-43 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 SMART SM00938 4 105 2.3E-65 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 Gene3D G3DSA:3.30.70.120 1 108 2.5E-46 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 PRINTS PR00340 P-II protein signature 23 41 4.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 PRINTS PR00340 P-II protein signature 83 103 4.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 PRINTS PR00340 P-II protein signature 2 17 4.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS12520 50fbec835956d3e284ebf7592dad7d76 112 PRINTS PR00340 P-II protein signature 52 75 4.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 SUPERFAMILY SSF51283 4 152 1.83E-47 T 28-03-2018 IPR029054 dUTPase-like AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 Pfam PF00692 dUTPase 17 151 3.6E-31 T 28-03-2018 IPR029054 dUTPase-like AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 Gene3D G3DSA:2.70.40.10 116 152 4.3E-16 T 28-03-2018 AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 Gene3D G3DSA:2.70.40.10 2 115 3.4E-40 T 28-03-2018 AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 TIGRFAM TIGR00576 dut: dUTP diphosphatase 17 152 1.0E-44 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 AFA_RS07495 b32e9f531f014792407da63e3a2ec8a8 153 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 7 152 28.185 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 AFA_RS05800 eb861ed2fb599cabb2457dddc181b513 87 SMART SM00530 19 74 7.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS05800 eb861ed2fb599cabb2457dddc181b513 87 Pfam PF01381 Helix-turn-helix 20 68 3.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS05800 eb861ed2fb599cabb2457dddc181b513 87 SUPERFAMILY SSF47413 13 81 2.17E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS05800 eb861ed2fb599cabb2457dddc181b513 87 Gene3D G3DSA:1.10.260.40 8 85 5.2E-16 T 28-03-2018 AFA_RS03105 e04256fae164eb2dd4a5adad8fdeb88d 327 Gene3D G3DSA:3.40.190.10 142 326 5.5E-4 T 28-03-2018 AFA_RS03105 e04256fae164eb2dd4a5adad8fdeb88d 327 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 28 283 7.1E-100 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS03105 e04256fae164eb2dd4a5adad8fdeb88d 327 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 28 311 1.2E-107 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS03105 e04256fae164eb2dd4a5adad8fdeb88d 327 PIRSF PIRSF006470 1 327 2.8E-133 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 SUPERFAMILY SSF46689 270 318 3.27E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 Gene3D G3DSA:1.10.10.60 273 321 1.1E-13 T 28-03-2018 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 312 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 SUPERFAMILY SSF46689 222 267 5.02E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 5.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 5.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 SUPERFAMILY SSF51182 43 97 3.71E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 Pfam PF12833 Helix-turn-helix domain 240 318 3.1E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 Gene3D G3DSA:2.60.120.280 29 198 1.6E-15 T 28-03-2018 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 SMART SM00342 234 316 3.3E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 Pfam PF12852 Cupin 26 197 1.9E-33 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFA_RS18220 e345a79b6aa04bcde325fde44eb9c1ef 322 Gene3D G3DSA:1.10.10.60 222 272 1.5E-9 T 28-03-2018 AFA_RS10940 0f3c4da0bf3ebebd574b8753b7d0f83e 231 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 26 229 3.6E-49 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS10940 0f3c4da0bf3ebebd574b8753b7d0f83e 231 Gene3D G3DSA:3.90.850.10 3 231 5.6E-73 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS10940 0f3c4da0bf3ebebd574b8753b7d0f83e 231 SUPERFAMILY SSF56529 21 231 3.01E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 623 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 SUPERFAMILY SSF48168 12 223 2.09E-72 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 475 498 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 300 319 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 435 446 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 541 564 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 513 535 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 612 639 6.0E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 147 737 1.3E-174 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 144 221 3.7E-13 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 Pfam PF03477 ATP cone domain 8 93 3.6E-16 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 SUPERFAMILY SSF51998 224 742 3.36E-167 T 28-03-2018 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 Gene3D G3DSA:3.20.70.20 124 741 4.0E-148 T 28-03-2018 AFA_RS03600 0ed607780194f4abf3528c1e3dc1f5b7 759 Pfam PF02867 Ribonucleotide reductase, barrel domain 225 733 2.0E-118 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS01110 096847e5e07cbce674b85492187f3f1d 277 SUPERFAMILY SSF52540 14 254 4.76E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01110 096847e5e07cbce674b85492187f3f1d 277 Pfam PF00005 ABC transporter 31 182 1.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01110 096847e5e07cbce674b85492187f3f1d 277 SMART SM00382 40 216 1.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01110 096847e5e07cbce674b85492187f3f1d 277 Gene3D G3DSA:3.40.50.300 10 256 3.8E-45 T 28-03-2018 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Pfam PF09317 Domain of unknown function (DUF1974) 474 762 4.9E-108 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 SUPERFAMILY SSF47203 320 467 7.57E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Gene3D G3DSA:1.10.540.10 35 195 1.3E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Gene3D G3DSA:2.40.110.10 196 309 4.2E-15 T 28-03-2018 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 320 467 2.7E-12 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Gene3D G3DSA:1.20.140.10 310 469 2.0E-21 T 28-03-2018 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 SUPERFAMILY SSF56645 78 315 4.06E-47 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS18145 81ff4e2eb7d7eb614e06124e1327968e 781 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 81 192 2.2E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 253 1.6E-66 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 Pfam PF01311 Bacterial export proteins, family 1 14 245 4.2E-69 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 1.8E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 1.8E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.8E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFA_RS05900 27dc5f26a967d5281715e510bd912d8d 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.8E-28 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFA_RS01955 4831f212817975481fc6906f816d719d 177 Pfam PF00227 Proteasome subunit 5 175 4.1E-22 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFA_RS01955 4831f212817975481fc6906f816d719d 177 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.219 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFA_RS01955 4831f212817975481fc6906f816d719d 177 SUPERFAMILY SSF56235 3 177 1.36E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS01955 4831f212817975481fc6906f816d719d 177 PIRSF PIRSF039093 1 177 6.8E-86 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFA_RS01955 4831f212817975481fc6906f816d719d 177 Gene3D G3DSA:3.60.20.10 7 177 2.2E-31 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS01955 4831f212817975481fc6906f816d719d 177 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 1.5E-84 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFA_RS02505 e6c248ea28f013cd4b530cc94b56ec9b 202 SUPERFAMILY SSF52833 6 196 2.24E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS02505 e6c248ea28f013cd4b530cc94b56ec9b 202 PIRSF PIRSF006386 1 201 2.2E-44 T 28-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 AFA_RS02505 e6c248ea28f013cd4b530cc94b56ec9b 202 Pfam PF01323 DSBA-like thioredoxin domain 7 195 1.1E-25 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 AFA_RS02505 e6c248ea28f013cd4b530cc94b56ec9b 202 Gene3D G3DSA:3.40.30.10 4 197 3.5E-33 T 28-03-2018 AFA_RS11790 410cd863ba719e808beb508bb6c6299e 416 Pfam PF07690 Major Facilitator Superfamily 36 373 8.2E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS11790 410cd863ba719e808beb508bb6c6299e 416 Gene3D G3DSA:1.20.1250.20 16 205 1.3E-21 T 28-03-2018 AFA_RS11790 410cd863ba719e808beb508bb6c6299e 416 Gene3D G3DSA:1.20.1250.20 215 413 8.9E-19 T 28-03-2018 AFA_RS11790 410cd863ba719e808beb508bb6c6299e 416 SUPERFAMILY SSF103473 14 405 4.58E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Gene3D G3DSA:3.30.470.20 455 620 1.6E-12 T 28-03-2018 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 SUPERFAMILY SSF52210 127 275 1.83E-28 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 274 9.8E-33 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Pfam PF13549 ATP-grasp domain 510 611 3.9E-9 T 28-03-2018 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Pfam PF13302 Acetyltransferase (GNAT) domain 653 799 7.1E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Gene3D G3DSA:3.40.50.261 277 443 6.4E-26 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Gene3D G3DSA:3.40.50.261 132 275 1.8E-25 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 SUPERFAMILY SSF52210 280 437 1.26E-23 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 SUPERFAMILY SSF55729 638 801 5.74E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Gene3D G3DSA:3.40.50.720 29 131 0.0014 T 28-03-2018 AFA_RS15565 9d27dbe0ab4c1bc4bd7ff2f0887a8a2d 823 Gene3D G3DSA:3.40.630.30 644 823 1.1E-27 T 28-03-2018 AFA_RS13260 13e70c5bb5a13cea4ebaaf0dc5df773c 131 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 6 129 2.0E-56 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFA_RS13260 13e70c5bb5a13cea4ebaaf0dc5df773c 131 SUPERFAMILY SSF51316 5 130 3.98E-60 T 28-03-2018 IPR011057 Mss4-like AFA_RS13260 13e70c5bb5a13cea4ebaaf0dc5df773c 131 Gene3D G3DSA:2.170.150.20 1 131 2.8E-62 T 28-03-2018 AFA_RS13260 13e70c5bb5a13cea4ebaaf0dc5df773c 131 Pfam PF01641 SelR domain 10 129 5.5E-55 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFA_RS13260 13e70c5bb5a13cea4ebaaf0dc5df773c 131 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 7 130 38.052 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFA_RS13025 e58be61c2fad83a5f19409ea0a4558bb 140 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 133 5.3E-38 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AFA_RS13025 e58be61c2fad83a5f19409ea0a4558bb 140 Gene3D G3DSA:3.40.50.10110 1 139 4.9E-44 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AFA_RS13025 e58be61c2fad83a5f19409ea0a4558bb 140 SUPERFAMILY SSF102400 1 138 3.92E-37 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AFA_RS10385 ec7ff269e1cc6aa9819bb91cdc8d81aa 189 SUPERFAMILY SSF55469 1 185 3.8E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFA_RS10385 ec7ff269e1cc6aa9819bb91cdc8d81aa 189 Pfam PF00881 Nitroreductase family 8 165 2.1E-22 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFA_RS10385 ec7ff269e1cc6aa9819bb91cdc8d81aa 189 PIRSF PIRSF000232 1 189 7.8E-52 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like AFA_RS10385 ec7ff269e1cc6aa9819bb91cdc8d81aa 189 Gene3D G3DSA:3.40.109.10 1 187 1.2E-29 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFA_RS07290 a5d8aa942a385783c92e3cd784a7b8b3 51 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 33 51 1.3E-7 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFA_RS07290 a5d8aa942a385783c92e3cd784a7b8b3 51 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 33 51 3.4E-9 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFA_RS16750 395db9de4b3701c631cdb42c0f2d17de 330 PIRSF PIRSF017082 1 330 5.8E-74 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS16750 395db9de4b3701c631cdb42c0f2d17de 330 SUPERFAMILY SSF53850 95 281 1.96E-7 T 28-03-2018 AFA_RS16750 395db9de4b3701c631cdb42c0f2d17de 330 Gene3D G3DSA:3.40.190.10 125 254 1.0E-11 T 28-03-2018 AFA_RS16750 395db9de4b3701c631cdb42c0f2d17de 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 73 322 5.1E-20 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 61 79 3.8E-18 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 25 50 3.8E-18 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 23 45 1.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 21 45 8.5E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 Gene3D G3DSA:3.30.700.10 39 155 1.8E-29 T 28-03-2018 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 Pfam PF08334 Type II secretion system (T2SS), protein G 49 155 5.0E-42 T 28-03-2018 IPR013545 Type II secretion system protein G AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 SUPERFAMILY SSF54523 52 156 1.36E-37 T 28-03-2018 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 24 156 7.4E-57 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 AFA_RS14290 5ab61f29223ad886bf4c1a8ad5cb77da 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 24 44 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 Gene3D G3DSA:2.60.120.10 21 112 1.2E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 Pfam PF02311 AraC-like ligand binding domain 20 110 1.3E-9 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 SUPERFAMILY SSF51182 28 190 2.36E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 SMART SM00342 168 250 2.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 205 246 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 Gene3D G3DSA:1.10.10.60 113 206 9.3E-10 T 28-03-2018 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 Pfam PF12833 Helix-turn-helix domain 174 251 6.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 Gene3D G3DSA:1.10.10.60 207 255 2.8E-9 T 28-03-2018 AFA_RS09230 6b1c58aa11ba0ccb19a819ce4a20621a 257 SUPERFAMILY SSF46689 204 253 1.79E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02560 95b07e58d3951cf2abaa3c10710f7198 361 SUPERFAMILY SSF52540 98 343 6.67E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02560 95b07e58d3951cf2abaa3c10710f7198 361 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 339 36.557 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein AFA_RS02560 95b07e58d3951cf2abaa3c10710f7198 361 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 338 7.6E-100 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFA_RS02560 95b07e58d3951cf2abaa3c10710f7198 361 Gene3D G3DSA:3.40.50.300 84 317 4.6E-65 T 28-03-2018 AFA_RS02560 95b07e58d3951cf2abaa3c10710f7198 361 ProSitePatterns PS01215 Mrp family signature. 202 218 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 AFA_RS11925 4f60daede73f115143ed78277d19f410 301 Gene3D G3DSA:3.40.50.1100 142 301 4.4E-40 T 28-03-2018 AFA_RS11925 4f60daede73f115143ed78277d19f410 301 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 300 2.3E-114 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFA_RS11925 4f60daede73f115143ed78277d19f410 301 SUPERFAMILY SSF53686 2 299 5.5E-82 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS11925 4f60daede73f115143ed78277d19f410 301 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 37 55 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFA_RS11925 4f60daede73f115143ed78277d19f410 301 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 289 4.2E-59 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS11925 4f60daede73f115143ed78277d19f410 301 Gene3D G3DSA:3.40.50.1100 45 141 1.5E-32 T 28-03-2018 AFA_RS11925 4f60daede73f115143ed78277d19f410 301 TIGRFAM TIGR01138 cysM: cysteine synthase B 6 300 2.3E-133 T 28-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFA_RS07445 7fdfc74144a1a951806a4a047cb2b0f4 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 294 4.9E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS07445 7fdfc74144a1a951806a4a047cb2b0f4 310 Gene3D G3DSA:1.10.3470.10 1 299 7.6E-53 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Gene3D G3DSA:3.40.50.300 10 463 5.6E-50 T 28-03-2018 AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 457 9.8E-58 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 SUPERFAMILY SSF52540 109 162 3.33E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 SUPERFAMILY SSF52540 835 858 3.33E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 SUPERFAMILY SSF52540 536 808 3.33E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 SUPERFAMILY SSF52540 335 506 3.33E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 SUPERFAMILY SSF52540 15 77 3.33E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Gene3D G3DSA:3.40.50.300 522 861 1.0E-36 T 28-03-2018 AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Pfam PF13361 UvrD-like helicase C-terminal domain 469 640 2.0E-10 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Pfam PF13361 UvrD-like helicase C-terminal domain 767 855 6.5E-10 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS09725 86b3ed0834e60d2d79c984d9ebdf43fd 1132 Gene3D G3DSA:3.90.320.10 876 1103 2.7E-7 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 SUPERFAMILY SSF52540 3 244 4.91E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 Pfam PF00005 ABC transporter 19 164 4.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 Gene3D G3DSA:3.40.50.300 1 271 3.2E-79 T 28-03-2018 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 SUPERFAMILY SSF50331 241 349 3.44E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 3.7E-117 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 Pfam PF12857 TOBE-like domain 294 349 3.4E-13 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 SMART SM00382 27 214 5.5E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11165 001abfe886ff8617b0482a7ccc010619 365 Gene3D G3DSA:2.40.50.100 296 348 3.0E-4 T 28-03-2018 AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 SUPERFAMILY SSF46785 158 231 1.31E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 Pfam PF00027 Cyclic nucleotide-binding domain 42 127 1.3E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 Gene3D G3DSA:1.10.10.10 158 237 4.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 SMART SM00419 174 222 2.0E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 Pfam PF13545 Crp-like helix-turn-helix domain 161 229 7.6E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 SUPERFAMILY SSF51206 13 151 1.05E-27 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 SMART SM00100 22 144 2.8E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS16810 901f4872389a6c8044777243c386eaf9 237 Gene3D G3DSA:2.60.120.10 14 157 1.8E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 Pfam PF13710 ACT domain 12 73 3.0E-16 T 28-03-2018 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 Gene3D G3DSA:3.30.70.260 1 87 5.7E-26 T 28-03-2018 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-33 T 28-03-2018 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 4.4E-64 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 Gene3D G3DSA:3.30.70.1150 88 160 1.1E-26 T 28-03-2018 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 SUPERFAMILY SSF55021 79 162 1.22E-25 T 28-03-2018 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 1.2E-26 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFA_RS13485 6754767edfe210debfaa9dfc9d5f0680 163 SUPERFAMILY SSF55021 1 76 1.75E-22 T 28-03-2018 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 SMART SM00649 9 141 2.8E-84 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 Gene3D G3DSA:1.10.10.250 73 141 3.1E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.557 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 9.3E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 5.0E-16 T 28-03-2018 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 2.1E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 7.9E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 SUPERFAMILY SSF54747 3 73 6.02E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 Gene3D G3DSA:3.30.1550.10 3 72 2.9E-33 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal AFA_RS18365 01edb3106fbe171968f699f1ba72e467 144 SUPERFAMILY SSF46906 68 141 1.7E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 SUPERFAMILY SSF50022 43 205 8.16E-41 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 144 2.5E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 PRINTS PR00162 Rieske 2Fe-2S subunit signature 165 177 2.5E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 23 204 2.6E-63 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 Gene3D G3DSA:1.20.5.510 19 47 1.3E-9 T 28-03-2018 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 Gene3D G3DSA:2.102.10.10 48 214 2.2E-43 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS17210 69ceb201d0fce071eb9e24bea71905b8 214 Pfam PF00355 Rieske [2Fe-2S] domain 124 193 1.4E-10 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 Pfam PF13354 Beta-lactamase enzyme family 54 258 3.9E-35 T 28-03-2018 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 33 57 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 103 128 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 218 233 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 64 81 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 165 190 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 139 163 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 PRINTS PR00118 Beta-lactamase class A signature 201 216 1.3E-60 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 SUPERFAMILY SSF56601 32 284 3.7E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 ProSitePatterns PS00146 Beta-lactamase class-A active site. 66 81 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 AFA_RS11700 ad88e78ad8f2588466c48510002523ee 291 Gene3D G3DSA:3.40.710.10 31 285 4.1E-27 T 28-03-2018 AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 Gene3D G3DSA:3.40.190.10 109 202 8.4E-12 T 28-03-2018 AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 SUPERFAMILY SSF46785 19 128 7.62E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 SUPERFAMILY SSF53850 109 320 1.38E-21 T 28-03-2018 AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 Pfam PF03466 LysR substrate binding domain 108 317 4.4E-21 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 Gene3D G3DSA:1.10.10.10 15 102 3.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 Gene3D G3DSA:3.40.190.10 203 287 1.7E-10 T 28-03-2018 AFA_RS03980 8b42768044e90dedfad1108981861f8f 331 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 22 81 1.2E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 Gene3D G3DSA:3.30.1340.10 1 87 1.5E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 9.3E-15 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 9.3E-15 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 9.3E-15 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 3.0E-29 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 SUPERFAMILY SSF55594 1 87 1.27E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS08685 61ff0e1b9ca137a9c09c21b8fece6c25 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 1.5E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like AFA_RS10885 bb48204cf3a41850e348ca1ba536c551 281 Pfam PF00482 Type II secretion system (T2SS), protein F 113 238 1.9E-13 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 Gene3D G3DSA:3.40.250.10 5 139 1.8E-14 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 Gene3D G3DSA:3.40.50.300 140 363 1.8E-4 T 28-03-2018 AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 SUPERFAMILY SSF52821 92 155 3.9E-19 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 SUPERFAMILY SSF52821 9 64 3.9E-19 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 1 363 53.268 T 28-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 SMART SM00450 2 133 8.0E-8 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16900 ef9d9772cbdf40c2c6e1505baca0f3d6 364 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 15 347 4.8E-114 T 28-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 AFA_RS16730 2df1ad39bba49dbc8e107e60c6285d2d 179 Gene3D G3DSA:2.30.110.10 4 172 5.6E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS16730 2df1ad39bba49dbc8e107e60c6285d2d 179 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 9 161 1.6E-38 T 28-03-2018 AFA_RS16730 2df1ad39bba49dbc8e107e60c6285d2d 179 SUPERFAMILY SSF50475 8 146 1.18E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS08055 a7a45101d269a945076039c6444cd33c 125 SUPERFAMILY SSF46458 1 104 1.26E-10 T 28-03-2018 IPR009050 Globin-like AFA_RS08055 a7a45101d269a945076039c6444cd33c 125 Gene3D G3DSA:1.10.490.10 54 104 5.9E-4 T 28-03-2018 AFA_RS08055 a7a45101d269a945076039c6444cd33c 125 Gene3D G3DSA:1.10.490.10 1 53 5.3E-4 T 28-03-2018 AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 6.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 6.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 6.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 244 2.3E-60 T 28-03-2018 AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 Gene3D G3DSA:3.40.50.720 1 252 2.4E-60 T 28-03-2018 AFA_RS00365 2b336ccda00b2e7cc62bdd54e503c630 260 SUPERFAMILY SSF51735 5 247 2.0E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS05305 9d9730a2fd14bbe3f756e1592fa57991 239 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 44 233 1.3E-37 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 AFA_RS05305 9d9730a2fd14bbe3f756e1592fa57991 239 SUPERFAMILY SSF56112 30 198 2.18E-17 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS05305 9d9730a2fd14bbe3f756e1592fa57991 239 Gene3D G3DSA:3.30.200.20 22 114 5.9E-8 T 28-03-2018 AFA_RS05305 9d9730a2fd14bbe3f756e1592fa57991 239 Gene3D G3DSA:3.90.1200.10 115 239 7.7E-9 T 28-03-2018 AFA_RS05305 9d9730a2fd14bbe3f756e1592fa57991 239 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 8 239 23.834 T 28-03-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 SMART SM00882 6 206 3.3E-75 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 Gene3D G3DSA:3.40.1080.10 3 216 1.9E-67 T 28-03-2018 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 Pfam PF01144 Coenzyme A transferase 7 204 8.0E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 3.1E-95 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 AFA_RS12925 7b6f3a5945baa7467257a4bbe8227c8a 217 SUPERFAMILY SSF100950 3 214 5.42E-71 T 28-03-2018 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 12 494 8.0E-226 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 Gene3D G3DSA:3.40.1080.10 13 238 1.9E-38 T 28-03-2018 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 320 463 1.7E-41 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 Gene3D G3DSA:3.40.1080.10 239 507 5.0E-57 T 28-03-2018 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 SUPERFAMILY SSF100950 226 495 1.94E-80 T 28-03-2018 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 SUPERFAMILY SSF100950 3 222 1.03E-69 T 28-03-2018 AFA_RS14700 a8a4e518928671d2569511f06c5e283e 507 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 10 215 4.2E-27 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 AFA_RS11045 a86ab93d6c960b3c390be713d999ed4e 105 Pfam PF04341 Protein of unknown function, DUF485 15 100 1.6E-21 T 28-03-2018 IPR007436 Protein of unknown function DUF485 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.2E-38 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 2.0E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 SUPERFAMILY SSF54719 81 191 4.71E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 SUPERFAMILY SSF46609 1 84 2.23E-36 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 Gene3D G3DSA:1.10.287.990 20 82 1.9E-27 T 28-03-2018 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PIRSF PIRSF000349 1 192 2.5E-86 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 9.7E-23 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.7E-23 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 9.7E-23 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 9.7E-23 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.7E-23 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS07385 25e2426686bc3cca4e311dc77069604f 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 Gene3D G3DSA:3.40.1050.10 1 210 4.3E-66 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 SUPERFAMILY SSF53056 1 200 7.85E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 Pfam PF00484 Carbonic anhydrase 34 188 3.6E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS02870 de3971d19f83e294fce590eb6823f9d6 216 SMART SM00947 27 193 2.3E-66 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 464 1.9E-44 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 576 39.923 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 SUPERFAMILY SSF55826 218 396 6.28E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Gene3D G3DSA:3.30.930.10 1 485 6.3E-102 T 28-03-2018 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.8E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.8E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.8E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.8E-17 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Pfam PF04073 Aminoacyl-tRNA editing domain 257 385 3.4E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 PIRSF PIRSF001535 1 577 1.4E-260 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Gene3D G3DSA:3.40.50.800 486 578 8.3E-26 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 SUPERFAMILY SSF55681 10 237 9.42E-103 T 28-03-2018 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 SUPERFAMILY SSF55681 412 483 9.42E-103 T 28-03-2018 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 572 8.3E-220 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 Pfam PF03129 Anticodon binding domain 481 570 2.2E-16 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS14605 2c9310f8257abe135564e162f8ec42d9 578 SUPERFAMILY SSF52954 469 575 4.23E-30 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS15450 e42aff97767fdd85f5fb9af6e5746641 240 Pfam PF14518 Iron-containing redox enzyme 42 220 9.6E-28 T 28-03-2018 IPR028201 PqqC-like protein AFA_RS15450 e42aff97767fdd85f5fb9af6e5746641 240 SMART SM01236 75 183 4.6E-21 T 28-03-2018 AFA_RS15450 e42aff97767fdd85f5fb9af6e5746641 240 Gene3D G3DSA:1.20.910.10 2 237 3.1E-34 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS15450 e42aff97767fdd85f5fb9af6e5746641 240 SUPERFAMILY SSF48613 6 228 1.63E-32 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Gene3D G3DSA:3.30.300.30 446 549 3.1E-26 T 28-03-2018 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Gene3D G3DSA:3.40.50.980 214 363 5.6E-41 T 28-03-2018 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 SUPERFAMILY SSF56801 18 549 1.83E-134 T 28-03-2018 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Pfam PF00501 AMP-binding enzyme 47 450 6.5E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Gene3D G3DSA:2.30.38.10 364 443 5.1E-15 T 28-03-2018 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Gene3D G3DSA:3.40.50.980 39 213 3.6E-36 T 28-03-2018 AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 537 7.4E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS15740 09ab9ccfaf21ac314a0d5d574dc6db08 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 171 0.0066 T 28-03-2018 AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 232 1.5E-53 T 28-03-2018 AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 Gene3D G3DSA:3.40.50.720 41 238 5.0E-53 T 28-03-2018 AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 Gene3D G3DSA:3.40.50.720 1 40 1.2E-8 T 28-03-2018 AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 5.0E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05290 eef1ed290f1bdae15127de896991a1c2 238 SUPERFAMILY SSF51735 2 235 3.78E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 158 219 7.7E-9 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 Pfam PF01743 Poly A polymerase head domain 13 131 1.1E-15 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 Gene3D G3DSA:1.10.3090.10 129 367 1.8E-26 T 28-03-2018 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 SUPERFAMILY SSF81301 10 129 1.96E-29 T 28-03-2018 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 SUPERFAMILY SSF81891 132 365 5.36E-29 T 28-03-2018 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 Gene3D G3DSA:3.30.460.10 8 128 3.0E-28 T 28-03-2018 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 PIRSF PIRSF000813 247 367 4.1E-9 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 AFA_RS02050 e9c2237860defefeb2c16304707536f8 367 PIRSF PIRSF000813 11 249 7.1E-104 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 Gene3D G3DSA:3.40.190.10 179 263 6.4E-10 T 28-03-2018 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 Gene3D G3DSA:1.10.10.10 5 81 1.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 Pfam PF03466 LysR substrate binding domain 91 295 5.9E-25 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 SUPERFAMILY SSF46785 3 85 1.69E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 Gene3D G3DSA:3.40.190.10 82 178 3.0E-15 T 28-03-2018 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 SUPERFAMILY SSF53850 95 296 1.05E-26 T 28-03-2018 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00090 f1439c0c6c6309278c4e987db6f4d347 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10290 375e75ada6a65801c0db6c94a63cf36f 690 Gene3D G3DSA:1.10.1370.10 142 437 1.2E-54 T 28-03-2018 AFA_RS10290 375e75ada6a65801c0db6c94a63cf36f 690 Gene3D G3DSA:1.10.1370.10 455 690 2.2E-59 T 28-03-2018 AFA_RS10290 375e75ada6a65801c0db6c94a63cf36f 690 SUPERFAMILY SSF55486 3 684 4.19E-184 T 28-03-2018 AFA_RS10290 375e75ada6a65801c0db6c94a63cf36f 690 Gene3D G3DSA:1.20.1050.40 7 140 3.7E-35 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal AFA_RS10290 375e75ada6a65801c0db6c94a63cf36f 690 Pfam PF01432 Peptidase family M3 224 684 1.1E-130 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 AFA_RS08165 20e7510328b99abb4db4dbf4896c37ff 135 SUPERFAMILY SSF102712 2 131 6.8E-27 T 28-03-2018 AFA_RS08165 20e7510328b99abb4db4dbf4896c37ff 135 Pfam PF14464 Prokaryotic homologs of the JAB domain 8 120 1.6E-20 T 28-03-2018 IPR028090 JAB domain, prokaryotic AFA_RS08165 20e7510328b99abb4db4dbf4896c37ff 135 Gene3D G3DSA:3.40.140.10 1 135 4.9E-26 T 28-03-2018 AFA_RS08165 20e7510328b99abb4db4dbf4896c37ff 135 SMART SM00232 2 132 1.0E-9 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 AFA_RS02140 dcee8062a210b802f1e517b8e8cc860b 126 Gene3D G3DSA:2.60.120.10 15 126 1.0E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02140 dcee8062a210b802f1e517b8e8cc860b 126 Pfam PF07883 Cupin domain 46 113 1.3E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS02140 dcee8062a210b802f1e517b8e8cc860b 126 SUPERFAMILY SSF51182 2 118 1.98E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS08015 e585c361930e2c44a84700ae10c0bf52 91 SMART SM01234 5 72 3.1E-47 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS08015 e585c361930e2c44a84700ae10c0bf52 91 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 19 72 3.0E-18 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS08015 e585c361930e2c44a84700ae10c0bf52 91 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 5 73 25.734 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS08015 e585c361930e2c44a84700ae10c0bf52 91 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 9 78 8.0E-34 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS08015 e585c361930e2c44a84700ae10c0bf52 91 Pfam PF01809 Haemolytic domain 8 72 7.3E-31 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS15705 9bbe46a29c1851776f4a29543b1b24b9 254 Pfam PF01553 Acyltransferase 60 176 1.0E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AFA_RS15705 9bbe46a29c1851776f4a29543b1b24b9 254 SMART SM00563 68 180 4.7E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AFA_RS15705 9bbe46a29c1851776f4a29543b1b24b9 254 SUPERFAMILY SSF69593 12 236 1.96E-26 T 28-03-2018 AFA_RS15705 9bbe46a29c1851776f4a29543b1b24b9 254 Gene3D G3DSA:3.40.1130.10 37 252 2.3E-31 T 28-03-2018 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 SUPERFAMILY SSF55961 172 378 2.2E-27 T 28-03-2018 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 Gene3D G3DSA:3.90.380.10 158 386 1.6E-35 T 28-03-2018 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 Gene3D G3DSA:2.102.10.10 53 157 2.4E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 192 378 2.6E-26 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 111 131 9.1E-13 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 90 110 9.1E-13 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 39 64 9.1E-13 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 Pfam PF00355 Rieske [2Fe-2S] domain 57 138 2.0E-13 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS08540 83db2f7089db525d062c79e19b233968 394 SUPERFAMILY SSF50022 24 166 3.01E-40 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS13495 cc88ebb37f2f3522a9c19209bfa238e0 761 Pfam PF12805 FUSC-like inner membrane protein yccS 75 350 2.6E-59 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal AFA_RS13495 cc88ebb37f2f3522a9c19209bfa238e0 761 Pfam PF13515 Fusaric acid resistance protein-like 436 548 1.5E-14 T 28-03-2018 AFA_RS05980 e689cfbc13d8e08efb9e800c6c6e9b01 111 Gene3D G3DSA:1.20.58.380 6 88 1.3E-20 T 28-03-2018 AFA_RS05980 e689cfbc13d8e08efb9e800c6c6e9b01 111 Pfam PF05400 Flagellar protein FliT 22 104 4.2E-17 T 28-03-2018 IPR008622 Flagellar protein FliT AFA_RS15780 e3e43af564e33330706f8db00125390d 385 SMART SM00359 287 370 1.0E-13 T 28-03-2018 IPR002478 PUA domain GO:0003723 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 9.6E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 9.6E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 9.6E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 9.6E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 9.6E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 Gene3D G3DSA:2.30.130.10 285 377 9.4E-30 T 28-03-2018 IPR002478 PUA domain GO:0003723 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 Pfam PF01472 PUA domain 287 359 1.6E-19 T 28-03-2018 IPR002478 PUA domain GO:0003723 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 Gene3D G3DSA:3.40.1160.10 3 275 1.4E-64 T 28-03-2018 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 377 7.2E-129 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 SUPERFAMILY SSF53633 15 264 4.45E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS15780 e3e43af564e33330706f8db00125390d 385 Pfam PF00696 Amino acid kinase family 16 243 5.3E-43 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS15780 e3e43af564e33330706f8db00125390d 385 PIRSF PIRSF000729 10 378 1.1E-127 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 272 36.251 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFA_RS15780 e3e43af564e33330706f8db00125390d 385 SUPERFAMILY SSF88697 287 377 9.39E-23 T 28-03-2018 IPR015947 PUA-like domain AFA_RS15630 f446aefe6b791f0cc17b014140a0d47c 313 SUPERFAMILY SSF53613 2 294 1.45E-62 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15630 f446aefe6b791f0cc17b014140a0d47c 313 Gene3D G3DSA:3.40.1190.20 3 312 1.3E-53 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15630 f446aefe6b791f0cc17b014140a0d47c 313 Pfam PF00294 pfkB family carbohydrate kinase 41 291 2.0E-38 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB AFA_RS15630 f446aefe6b791f0cc17b014140a0d47c 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 49 73 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 Pfam PF00171 Aldehyde dehydrogenase family 29 494 3.1E-164 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 SUPERFAMILY SSF53720 16 500 1.22E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 Gene3D G3DSA:3.40.309.10 282 482 2.1E-66 T 28-03-2018 AFA_RS04755 a4f84221aa1c822c4ace24cc23785e4e 508 Gene3D G3DSA:3.40.605.10 13 281 3.1E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS05380 fbe1163ab47a57184af5c3acd837da0b 265 Gene3D G3DSA:3.90.550.10 2 257 1.9E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS05380 fbe1163ab47a57184af5c3acd837da0b 265 SUPERFAMILY SSF53448 16 161 9.38E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS05380 fbe1163ab47a57184af5c3acd837da0b 265 Pfam PF00535 Glycosyl transferase family 2 19 138 3.2E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 Gene3D G3DSA:3.30.70.920 54 152 3.6E-17 T 28-03-2018 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 SUPERFAMILY SSF46785 3 63 1.03E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 Gene3D G3DSA:1.10.10.10 1 53 3.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 8.1E-16 T 28-03-2018 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 2.1E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 SMART SM00344 4 113 7.5E-30 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 8.0E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 8.0E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS17490 bb6e523c243c118a3ac62df00edd5d7c 158 SUPERFAMILY SSF54909 66 153 1.61E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 Gene3D G3DSA:3.20.20.70 373 612 0.0017 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 Pfam PF01522 Polysaccharide deacetylase 103 269 8.9E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 Gene3D G3DSA:3.20.20.370 43 361 1.1E-44 T 28-03-2018 AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 SUPERFAMILY SSF88713 223 282 5.56E-37 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 SUPERFAMILY SSF88713 65 195 5.56E-37 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 317 645 1.0E-137 T 28-03-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal AFA_RS08835 f71dff8f3ddee17d8904e31258db6fe6 673 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 49 664 7.3E-259 T 28-03-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0042710 AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 PIRSF PIRSF015753 4 323 9.5E-129 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 Gene3D G3DSA:1.20.1050.10 188 326 2.1E-42 T 28-03-2018 AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 1.5E-21 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 SUPERFAMILY SSF47616 177 323 1.27E-33 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 SUPERFAMILY SSF52833 42 161 3.69E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 Gene3D G3DSA:3.40.30.10 41 187 1.1E-33 T 28-03-2018 AFA_RS04675 847910d99af5a28c538552dc9b0c62b0 337 Pfam PF13410 Glutathione S-transferase, C-terminal domain 202 273 2.2E-11 T 28-03-2018 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.5E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 SMART SM00322 60 125 1.6E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 Gene3D G3DSA:3.30.1140.32 108 207 1.8E-37 T 28-03-2018 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 SUPERFAMILY SSF54814 2 106 1.2E-35 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 Pfam PF07650 KH domain 39 110 7.1E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 Gene3D G3DSA:3.30.300.20 17 107 9.2E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.4E-92 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 SUPERFAMILY SSF54821 108 206 3.92E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18240 5329ba51a0196283ebe43d25aa767c41 257 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.7 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 Pfam PF01025 GrpE 41 193 6.1E-46 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 SUPERFAMILY SSF51064 143 194 3.53E-15 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 Gene3D G3DSA:3.90.20.20 37 137 4.7E-25 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 SUPERFAMILY SSF58014 46 136 4.84E-23 T 28-03-2018 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 Hamap MF_01151 Protein GrpE [grpE]. 8 194 19.448 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 Gene3D G3DSA:2.30.22.10 139 196 3.0E-19 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 ProSitePatterns PS01071 grpE protein signature. 150 192 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 PRINTS PR00773 GrpE protein signature 173 192 1.6E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 PRINTS PR00773 GrpE protein signature 94 109 1.6E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 PRINTS PR00773 GrpE protein signature 147 162 1.6E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS13755 4d6c69e9485fb7f64cfb0751ff839ddb 196 PRINTS PR00773 GrpE protein signature 66 82 1.6E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 PIRSF PIRSF001563 5 391 1.6E-101 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 PIRSF PIRSF001563 392 463 0.16 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 SUPERFAMILY SSF53623 11 289 1.95E-87 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 Gene3D G3DSA:3.90.190.20 296 462 2.7E-25 T 28-03-2018 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 Pfam PF02875 Mur ligase family, glutamate ligase domain 291 366 1.9E-6 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 TIGRFAM TIGR01499 folC: bifunctional protein FolC 31 455 2.8E-101 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 Gene3D G3DSA:3.40.1190.10 2 291 4.0E-77 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 SUPERFAMILY SSF53244 291 378 1.68E-28 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 SUPERFAMILY SSF53244 418 455 1.68E-28 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS10255 e2dce9dcea29ce7448991b3b4c8fb13e 463 Pfam PF08245 Mur ligase middle domain 52 266 6.4E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 SUPERFAMILY SSF46689 253 303 3.45E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 Gene3D G3DSA:1.10.10.60 196 255 6.5E-12 T 28-03-2018 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 Gene3D G3DSA:1.10.10.60 256 307 2.0E-12 T 28-03-2018 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 254 296 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 Pfam PF12833 Helix-turn-helix domain 226 302 2.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 Gene3D G3DSA:2.60.120.280 14 187 2.6E-8 T 28-03-2018 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 SUPERFAMILY SSF46689 200 251 2.15E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 Pfam PF12852 Cupin 5 184 2.1E-31 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFA_RS08985 d2c462bccfce4453200569d7c6734166 307 SMART SM00342 217 300 6.2E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 9.8E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 4 401 4.3E-217 T 28-03-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 Pfam PF00108 Thiolase, N-terminal domain 6 267 2.4E-74 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 SUPERFAMILY SSF53901 277 400 4.03E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 Gene3D G3DSA:3.40.47.10 2 274 1.1E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 SUPERFAMILY SSF53901 4 276 1.47E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 PIRSF PIRSF000429 1 401 2.2E-126 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 5.7E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS07395 c5ae73dd53635acabe68a621aca29683 401 Gene3D G3DSA:3.40.47.10 275 398 2.2E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS04790 10f9b716cd5186b37ca7f36add7f2664 386 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 18 42 0.001 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFA_RS04790 10f9b716cd5186b37ca7f36add7f2664 386 PIRSF PIRSF039026 17 377 1.7E-128 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS04790 10f9b716cd5186b37ca7f36add7f2664 386 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 54 329 1.1E-38 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS09105 024977eab7ff70509eff2de2728410b3 278 Pfam PF00691 OmpA family 162 260 8.8E-21 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS09105 024977eab7ff70509eff2de2728410b3 278 Gene3D G3DSA:3.30.1330.60 3 277 1.1E-38 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS09105 024977eab7ff70509eff2de2728410b3 278 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 56 82 3.1E-8 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain AFA_RS09105 024977eab7ff70509eff2de2728410b3 278 SUPERFAMILY SSF103088 151 266 8.63E-31 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Pfam PF09330 D-lactate dehydrogenase, membrane binding 276 564 1.4E-133 T 28-03-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Gene3D G3DSA:3.30.43.10 2 101 4.2E-12 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Pfam PF01565 FAD binding domain 45 183 8.8E-8 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Gene3D G3DSA:3.30.1370.20 432 515 2.8E-39 T 28-03-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Gene3D G3DSA:3.30.465.10 105 267 3.0E-77 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 SUPERFAMILY SSF55103 275 564 2.07E-105 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 PIRSF PIRSF000101 2 566 7.9E-272 T 28-03-2018 IPR012256 D-lactate dehydrogenase GO:0004457|GO:0005887|GO:0006089|GO:0050660|GO:0051287 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 SUPERFAMILY SSF56176 9 271 7.01E-71 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Gene3D G3DSA:3.30.70.610 268 350 7.3E-16 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 AFA_RS02210 fe1d658e960d921fd820d4dc4b161b19 573 Gene3D G3DSA:3.30.70.610 354 431 8.4E-23 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 SUPERFAMILY SSF48163 309 466 5.62E-37 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Gene3D G3DSA:3.40.50.620 130 241 1.4E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Gene3D G3DSA:1.10.8.70 328 370 7.1E-5 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Gene3D G3DSA:1.10.10.350 378 469 4.7E-18 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 3.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 3.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 205 213 3.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 189 199 3.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 3.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 8 469 30.666 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 315 4.1E-106 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Gene3D G3DSA:3.40.50.620 4 129 1.6E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 SUPERFAMILY SSF52374 9 305 2.41E-111 T 28-03-2018 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 Gene3D G3DSA:1.10.1160.10 242 323 2.8E-32 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 AFA_RS15585 c12b92560a8f1f33b03894c99bc2155b 469 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 466 2.5E-169 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFA_RS02660 65d7474bed1f560838683c1afc3cbf94 262 PIRSF PIRSF006241 1 261 5.5E-96 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 AFA_RS02660 65d7474bed1f560838683c1afc3cbf94 262 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 254 1.0E-118 T 28-03-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 AFA_RS02660 65d7474bed1f560838683c1afc3cbf94 262 SUPERFAMILY SSF51658 1 257 3.8E-87 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFA_RS02660 65d7474bed1f560838683c1afc3cbf94 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 3.6E-34 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFA_RS02660 65d7474bed1f560838683c1afc3cbf94 262 Gene3D G3DSA:3.20.20.150 1 260 1.9E-58 T 28-03-2018 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 195 4.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 8.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 8.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 8.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 8.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 Gene3D G3DSA:1.10.150.240 26 101 4.7E-24 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 195 2.4E-37 T 28-03-2018 IPR023214 HAD-like domain AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 Gene3D G3DSA:3.40.50.1000 102 230 9.6E-32 T 28-03-2018 IPR023214 HAD-like domain AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 SUPERFAMILY SSF56784 9 224 2.26E-59 T 28-03-2018 IPR023214 HAD-like domain AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 188 2.5E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS01365 44b118e4e712c39b27228e3087dcaccb 234 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 14 219 5.1E-63 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 SUPERFAMILY SSF55681 3 286 1.94E-132 T 28-03-2018 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 286 2.0E-149 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 287 60.431 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 247 263 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 1.1E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 Gene3D G3DSA:1.20.58.180 212 288 9.1E-35 T 28-03-2018 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 293 8.1E-157 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03850 6590c9bef1e909dbb1f37b4acf7f9d99 301 Gene3D G3DSA:3.30.930.10 1 210 3.5E-90 T 28-03-2018 AFA_RS10800 a69cc70044b74d2906639de985d368d7 214 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 42.439 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFA_RS10800 a69cc70044b74d2906639de985d368d7 214 Pfam PF00694 Aconitase C-terminal domain 1 131 1.2E-37 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS10800 a69cc70044b74d2906639de985d368d7 214 SUPERFAMILY SSF52016 1 200 1.24E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS10800 a69cc70044b74d2906639de985d368d7 214 Gene3D G3DSA:3.20.19.10 1 184 2.3E-47 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS10800 a69cc70044b74d2906639de985d368d7 214 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 2.4E-78 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 296 64.155 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 Gene3D G3DSA:3.20.20.70 6 303 2.0E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 SMART SM01130 10 298 9.0E-138 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 3.6E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 3.6E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 3.6E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 3.6E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 PIRSF PIRSF001365 7 301 6.8E-87 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 SUPERFAMILY SSF51569 9 298 1.03E-100 T 28-03-2018 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 Pfam PF00701 Dihydrodipicolinate synthetase family 10 295 3.0E-98 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS04340 0cd949d068873bd372a2387f506dc0ca 303 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 295 1.9E-103 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 Pfam PF13411 MerR HTH family regulatory protein 1 68 4.0E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 Gene3D G3DSA:1.10.1660.10 1 55 7.3E-21 T 28-03-2018 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 Gene3D G3DSA:1.10.1660.10 56 135 3.7E-18 T 28-03-2018 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 SMART SM00422 1 70 2.0E-22 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 1.7E-54 T 28-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 AFA_RS05680 a6db301e31aaba4a8a6404da6226790d 143 SUPERFAMILY SSF46955 1 126 4.76E-35 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Pfam PF00027 Cyclic nucleotide-binding domain 50 130 2.3E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Gene3D G3DSA:3.10.580.10 170 292 5.3E-25 T 28-03-2018 AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Pfam PF00571 CBS domain 178 226 7.4E-9 T 28-03-2018 IPR000644 CBS domain AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Pfam PF00571 CBS domain 237 288 6.6E-9 T 28-03-2018 IPR000644 CBS domain AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 SUPERFAMILY SSF54631 177 287 3.41E-26 T 28-03-2018 AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 SUPERFAMILY SSF51206 28 147 2.23E-13 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Gene3D G3DSA:2.60.120.10 25 152 4.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 491 634 7.3E-33 T 28-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 Pfam PF03445 Putative nucleotidyltransferase DUF294 315 454 4.0E-42 T 28-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 SMART SM00116 243 290 2.8E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS05890 841a3f56430b10a0f46b6e6cba1708f4 636 SMART SM00116 178 226 2.0E-7 T 28-03-2018 IPR000644 CBS domain AFA_RS05250 559b6c56089219452f8839286b93521b 432 Gene3D G3DSA:3.40.50.720 2 160 2.1E-33 T 28-03-2018 AFA_RS05250 559b6c56089219452f8839286b93521b 432 Pfam PF00742 Homoserine dehydrogenase 137 315 3.3E-64 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFA_RS05250 559b6c56089219452f8839286b93521b 432 Gene3D G3DSA:3.30.360.10 161 298 1.2E-52 T 28-03-2018 AFA_RS05250 559b6c56089219452f8839286b93521b 432 Pfam PF01842 ACT domain 354 418 2.2E-12 T 28-03-2018 IPR002912 ACT domain AFA_RS05250 559b6c56089219452f8839286b93521b 432 SUPERFAMILY SSF55021 346 423 3.23E-13 T 28-03-2018 AFA_RS05250 559b6c56089219452f8839286b93521b 432 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFA_RS05250 559b6c56089219452f8839286b93521b 432 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 6.6E-22 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFA_RS05250 559b6c56089219452f8839286b93521b 432 SUPERFAMILY SSF55347 137 302 3.2E-53 T 28-03-2018 AFA_RS05250 559b6c56089219452f8839286b93521b 432 PIRSF PIRSF000098 1 432 6.6E-164 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFA_RS05250 559b6c56089219452f8839286b93521b 432 Gene3D G3DSA:3.30.70.260 350 428 9.8E-17 T 28-03-2018 AFA_RS05250 559b6c56089219452f8839286b93521b 432 SUPERFAMILY SSF51735 1 158 4.62E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 Gene3D G3DSA:3.40.50.2300 10 174 1.0E-28 T 28-03-2018 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 Gene3D G3DSA:3.40.50.2300 175 343 1.0E-12 T 28-03-2018 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 Pfam PF13433 Periplasmic binding protein domain 14 377 7.4E-142 T 28-03-2018 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 SUPERFAMILY SSF53822 13 382 3.53E-92 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 36 52 8.4E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 244 262 8.4E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 14 30 8.4E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS14135 7a83614f74bd571c4cd7772a6d37e715 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 73 8.4E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS04955 3164aa1e30ebb9a897be0981dac153c8 168 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 33 159 6.7E-15 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 6.1E-254 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 SUPERFAMILY SSF143975 3 423 1.44E-133 T 28-03-2018 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 44.912 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 Gene3D G3DSA:3.40.50.2300 54 186 1.3E-4 T 28-03-2018 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 Pfam PF00920 Dehydratase family 34 610 4.3E-218 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 SUPERFAMILY SSF52016 424 615 1.57E-60 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS02080 19a1ac4b854ad6aac9e75b75fba85c29 619 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Gene3D G3DSA:3.40.640.10 151 458 3.7E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 SUPERFAMILY SSF53383 151 604 2.35E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Gene3D G3DSA:3.90.100.10 635 756 3.9E-32 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 1.2E-38 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 584 5.8E-150 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 PIRSF PIRSF009393 1 753 4.6E-274 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Gene3D G3DSA:3.90.1150.10 459 634 1.1E-72 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 611 735 2.3E-44 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS02580 515afc6746d58f500f0acb344c8fae45 757 SUPERFAMILY SSF55904 606 750 1.02E-43 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 SMART SM00490 260 341 1.5E-24 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 Gene3D G3DSA:3.40.50.300 15 225 2.7E-58 T 28-03-2018 AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 Pfam PF03880 DbpA RNA binding domain 391 461 4.0E-22 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 Pfam PF00271 Helicase conserved C-terminal domain 236 340 7.8E-26 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 SMART SM00487 27 224 1.5E-59 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 Gene3D G3DSA:3.40.50.300 226 461 2.2E-40 T 28-03-2018 AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 Pfam PF00270 DEAD/DEAH box helicase 32 199 4.7E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS13885 d005eba57e1eda27ac7841799f029fa6 466 SUPERFAMILY SSF52540 77 362 4.06E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12805 3ec0e2a90f28f90bb5c1e56f5b69bc78 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 278 9.3E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12805 3ec0e2a90f28f90bb5c1e56f5b69bc78 285 Gene3D G3DSA:1.10.3720.10 40 285 7.7E-36 T 28-03-2018 AFA_RS12805 3ec0e2a90f28f90bb5c1e56f5b69bc78 285 SUPERFAMILY SSF161098 88 272 1.06E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14230 a7e7e10a969871c58b2de27cbf680089 429 SMART SM00052 153 398 4.6E-19 T 28-03-2018 IPR001633 EAL domain AFA_RS14230 a7e7e10a969871c58b2de27cbf680089 429 Gene3D G3DSA:3.20.20.450 143 395 5.9E-47 T 28-03-2018 IPR001633 EAL domain AFA_RS14230 a7e7e10a969871c58b2de27cbf680089 429 Pfam PF00563 EAL domain 164 391 1.2E-45 T 28-03-2018 IPR001633 EAL domain AFA_RS14230 a7e7e10a969871c58b2de27cbf680089 429 SUPERFAMILY SSF141868 165 393 1.83E-46 T 28-03-2018 IPR001633 EAL domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Gene3D G3DSA:3.30.450.20 230 291 1.4E-4 T 28-03-2018 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 529 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 548 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 7.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 419 2.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 567 4.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SUPERFAMILY SSF47384 340 419 2.35E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Gene3D G3DSA:3.30.450.20 292 344 0.0016 T 28-03-2018 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Gene3D G3DSA:1.10.287.130 345 418 1.6E-8 T 28-03-2018 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Gene3D G3DSA:3.30.450.20 91 229 1.2E-28 T 28-03-2018 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Gene3D G3DSA:3.30.565.10 423 578 3.8E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SUPERFAMILY SSF55785 95 220 7.85E-23 T 28-03-2018 IPR000014 PAS domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Pfam PF13188 PAS domain 234 290 0.0011 T 28-03-2018 IPR000014 PAS domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 Pfam PF08448 PAS fold 115 224 1.6E-16 T 28-03-2018 IPR013656 PAS fold-4 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SMART SM00388 352 422 7.7E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SMART SM00387 464 570 6.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SUPERFAMILY SSF55874 411 574 6.67E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SMART SM00086 180 222 4.8E-4 T 28-03-2018 IPR001610 PAC motif AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 107 229 1.9E-26 T 28-03-2018 IPR000014 PAS domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SMART SM00091 234 308 53.0 T 28-03-2018 IPR000014 PAS domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SMART SM00091 106 173 1.6E-8 T 28-03-2018 IPR000014 PAS domain AFA_RS10275 aabee3e292a4972ec2facd60debd3936 585 SUPERFAMILY SSF55785 219 328 6.98E-8 T 28-03-2018 IPR000014 PAS domain AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 PRINTS PR00108 Thymidylate synthase family signature 143 158 2.0E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 PRINTS PR00108 Thymidylate synthase family signature 161 187 2.0E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 PRINTS PR00108 Thymidylate synthase family signature 44 65 2.0E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 PRINTS PR00108 Thymidylate synthase family signature 117 136 2.0E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 PRINTS PR00108 Thymidylate synthase family signature 199 216 2.0E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 ProSitePatterns PS00091 Thymidylate synthase active site. 128 156 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 266 3.4E-99 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 87 1.4E-37 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 Pfam PF00303 Thymidylate synthase 6 266 1.9E-124 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 Hamap MF_00008 Thymidylate synthase [thyA]. 3 266 39.445 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 Gene3D G3DSA:3.30.572.10 3 266 3.2E-130 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02600 223729099a839fb53c8ba28080f8b9ab 266 SUPERFAMILY SSF55831 5 266 8.24E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 SUPERFAMILY SSF103473 463 490 6.54E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 SUPERFAMILY SSF103473 3 194 6.54E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 SUPERFAMILY SSF103473 242 413 6.54E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 Gene3D G3DSA:1.20.1250.20 2 195 6.8E-27 T 28-03-2018 AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 483 5.4E-84 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 Gene3D G3DSA:1.20.1250.20 246 498 1.2E-32 T 28-03-2018 AFA_RS02340 7a456e36de6c714e9e97f75897d2caf9 502 Pfam PF07690 Major Facilitator Superfamily 11 403 9.0E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 SUPERFAMILY SSF47413 10 67 6.49E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 SUPERFAMILY SSF53822 91 342 3.21E-34 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Gene3D G3DSA:3.40.50.2300 188 321 1.2E-26 T 28-03-2018 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 SMART SM00354 11 81 1.8E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Pfam PF13377 Periplasmic binding protein-like domain 182 341 2.3E-23 T 28-03-2018 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 4.6E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Gene3D G3DSA:1.10.260.40 27 67 1.4E-20 T 28-03-2018 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Gene3D G3DSA:3.40.50.2300 68 187 2.7E-15 T 28-03-2018 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 Gene3D G3DSA:1.10.10.10 5 26 0.022 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 28-03-2018 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.8E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS08595 9a24c0ff7eb0f0e399f5cc586da8fc57 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 23 33 3.8E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS04115 93528d9feaaf278c45079c53b55997e1 264 SUPERFAMILY SSF161098 58 241 6.8E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04115 93528d9feaaf278c45079c53b55997e1 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 6.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04115 93528d9feaaf278c45079c53b55997e1 264 Gene3D G3DSA:1.10.3720.10 13 255 1.1E-24 T 28-03-2018 AFA_RS02105 8e60ea1cb8f6e1836fe46aa04de430a2 465 Pfam PF01425 Amidase 33 447 9.0E-89 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS02105 8e60ea1cb8f6e1836fe46aa04de430a2 465 Gene3D G3DSA:3.90.1300.10 7 464 1.0E-124 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS02105 8e60ea1cb8f6e1836fe46aa04de430a2 465 SUPERFAMILY SSF75304 8 458 2.22E-118 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS07760 4e88013707d0918a5280f3e550b657e8 90 SUPERFAMILY SSF50249 1 71 3.14E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS07760 4e88013707d0918a5280f3e550b657e8 90 Gene3D G3DSA:2.40.50.140 1 72 8.5E-32 T 28-03-2018 AFA_RS07760 4e88013707d0918a5280f3e550b657e8 90 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 7.1E-23 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFA_RS07760 4e88013707d0918a5280f3e550b657e8 90 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.8E-31 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFA_RS07760 4e88013707d0918a5280f3e550b657e8 90 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 74 26.1 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 SUPERFAMILY SSF56801 4 504 7.98E-146 T 28-03-2018 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Gene3D G3DSA:2.30.38.10 318 403 1.2E-24 T 28-03-2018 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 494 2.9E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Gene3D G3DSA:3.30.300.30 404 505 4.0E-29 T 28-03-2018 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Gene3D G3DSA:3.40.50.980 166 317 2.9E-36 T 28-03-2018 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Gene3D G3DSA:3.40.50.980 2 165 4.9E-41 T 28-03-2018 AFA_RS00125 e3a95ac349e91b666706d025abe36315 505 Pfam PF00501 AMP-binding enzyme 11 410 5.6E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS17160 b55277591e36c236fd9dc0826adf44ba 263 Pfam PF00977 Histidine biosynthesis protein 12 245 1.1E-86 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 AFA_RS17160 b55277591e36c236fd9dc0826adf44ba 263 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 9 262 1.2E-107 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFA_RS17160 b55277591e36c236fd9dc0826adf44ba 263 Gene3D G3DSA:3.20.20.70 11 258 3.7E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS17160 b55277591e36c236fd9dc0826adf44ba 263 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 8 262 47.093 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFA_RS17160 b55277591e36c236fd9dc0826adf44ba 263 SUPERFAMILY SSF51366 10 262 2.9E-80 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 Pfam PF00106 short chain dehydrogenase 3 204 1.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 SUPERFAMILY SSF51735 2 239 7.85E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 Gene3D G3DSA:3.40.50.720 148 245 1.2E-13 T 28-03-2018 AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 Gene3D G3DSA:3.40.50.720 1 146 1.0E-40 T 28-03-2018 AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.8E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.8E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.8E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 9.8E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.8E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06560 2380101c4111c050c8d4a25e004de789 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07485 832b7ea25eb858f72cb2317b81620619 394 Gene3D G3DSA:3.40.1350.10 260 378 1.0E-19 T 28-03-2018 AFA_RS07485 832b7ea25eb858f72cb2317b81620619 394 SUPERFAMILY SSF52980 265 374 2.04E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS07485 832b7ea25eb858f72cb2317b81620619 394 Pfam PF04471 Restriction endonuclease 262 368 2.0E-25 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 Gene3D G3DSA:3.30.450.90 73 210 2.1E-47 T 28-03-2018 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 Gene3D G3DSA:3.40.50.300 211 472 1.7E-63 T 28-03-2018 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 Pfam PF00437 Type II/IV secretion system protein 113 377 1.9E-84 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 SUPERFAMILY SSF160246 2 64 1.05E-7 T 28-03-2018 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 SUPERFAMILY SSF52540 87 469 6.12E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 2 469 4.8E-205 T 28-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 SMART SM00382 238 359 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14245 699111cbf1318b7d49e7ff91beab7bf3 472 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 305 319 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 6.5E-40 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 283 1.1E-23 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 SUPERFAMILY SSF48179 162 284 1.7E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 Gene3D G3DSA:3.40.50.720 1 170 3.5E-29 T 28-03-2018 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 Gene3D G3DSA:1.10.1040.10 171 289 2.7E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 PIRSF PIRSF000103 1 291 4.0E-67 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS17310 a238130f41d68cb3a7020c7929e94317 298 SUPERFAMILY SSF51735 1 162 3.07E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS05180 0886ec82dc15617e45fbfd417e53d8bb 302 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 221 233 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site AFA_RS05180 0886ec82dc15617e45fbfd417e53d8bb 302 SUPERFAMILY SSF48576 5 279 3.29E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS05180 0886ec82dc15617e45fbfd417e53d8bb 302 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 91 107 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site AFA_RS05180 0886ec82dc15617e45fbfd417e53d8bb 302 Pfam PF00348 Polyprenyl synthetase 34 267 1.8E-51 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFA_RS05180 0886ec82dc15617e45fbfd417e53d8bb 302 Gene3D G3DSA:1.10.600.10 1 302 2.9E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 Gene3D G3DSA:2.40.30.60 9 106 6.5E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 Gene3D G3DSA:2.30.30.240 108 194 1.0E-19 T 28-03-2018 AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 11 197 4.5E-38 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 SUPERFAMILY SSF50447 9 106 1.13E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 10 199 22.292 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 Pfam PF01782 RimM N-terminal domain 12 102 2.0E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 AFA_RS11605 ce26d696a45fde57c6c4fa42e43105d0 199 SUPERFAMILY SSF50346 112 197 3.85E-10 T 28-03-2018 IPR011033 PRC-barrel-like AFA_RS10670 6e07426a18546394c7499fab453ed8dd 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 44 284 3.4E-60 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS10670 6e07426a18546394c7499fab453ed8dd 330 Gene3D G3DSA:3.40.190.10 141 220 6.1E-5 T 28-03-2018 AFA_RS10670 6e07426a18546394c7499fab453ed8dd 330 PIRSF PIRSF006470 2 329 1.3E-80 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS10670 6e07426a18546394c7499fab453ed8dd 330 SUPERFAMILY SSF53850 137 286 2.38E-5 T 28-03-2018 AFA_RS10670 6e07426a18546394c7499fab453ed8dd 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 312 6.0E-74 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 162 336 1.6E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 94 156 2.0E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 138 156 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 SUPERFAMILY SSF53335 20 156 6.09E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 272 286 3.6E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 161 177 3.6E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 318 331 3.6E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 SUPERFAMILY SSF53335 162 394 7.16E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 Gene3D G3DSA:3.40.50.150 161 327 1.0E-41 T 28-03-2018 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 Gene3D G3DSA:3.90.120.10 21 145 5.8E-17 T 28-03-2018 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 Gene3D G3DSA:3.90.120.10 328 393 1.4E-4 T 28-03-2018 AFA_RS06300 946664c035ca2c511470a5f8aebdaf07 410 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 163 332 1.5E-34 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 Gene3D G3DSA:1.10.10.10 12 91 6.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 Gene3D G3DSA:3.30.450.40 97 262 5.4E-45 T 28-03-2018 IPR029016 GAF domain-like AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 Pfam PF09339 IclR helix-turn-helix domain 22 70 5.8E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 SMART SM00346 23 108 0.007 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 Pfam PF01614 Bacterial transcriptional regulator 137 260 3.4E-28 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 SUPERFAMILY SSF46785 22 86 9.45E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10705 28ba14bb6f2519194ead0e48490e5cb2 269 SUPERFAMILY SSF55781 98 260 7.19E-45 T 28-03-2018 IPR029016 GAF domain-like AFA_RS10235 a2340c41f23efe09b84132d1f3e6f114 170 Gene3D G3DSA:1.20.120.450 1 150 1.4E-16 T 28-03-2018 AFA_RS10235 a2340c41f23efe09b84132d1f3e6f114 170 PIRSF PIRSF031551 1 170 3.1E-51 T 28-03-2018 IPR012550 Protein of unknown function DUF1706 AFA_RS10235 a2340c41f23efe09b84132d1f3e6f114 170 Pfam PF08020 Protein of unknown function (DUF1706) 1 165 2.1E-53 T 28-03-2018 IPR012550 Protein of unknown function DUF1706 AFA_RS10235 a2340c41f23efe09b84132d1f3e6f114 170 SUPERFAMILY SSF109854 6 146 2.38E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 SMART SM00448 6 117 8.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 8.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 SMART SM00421 141 198 7.8E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 Pfam PF00072 Response regulator receiver domain 8 117 8.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 SUPERFAMILY SSF46894 132 198 1.9E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 Gene3D G3DSA:3.40.50.2300 1 131 5.4E-30 T 28-03-2018 AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 Gene3D G3DSA:1.10.10.10 132 203 6.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 SUPERFAMILY SSF52172 8 154 5.12E-32 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS03095 c35279aa5d9bb75c02364b26a2aeab8f 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 108 188 5.2E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS08195 ae5880f26f2d8bee1da74f21159cb4fd 346 SUPERFAMILY SSF48208 11 343 7.48E-36 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 AFA_RS08195 ae5880f26f2d8bee1da74f21159cb4fd 346 Gene3D G3DSA:1.50.10.10 7 346 1.6E-26 T 28-03-2018 AFA_RS05425 bb5ea311a5fe20b70991bc35d863d3b9 159 SUPERFAMILY SSF52540 1 122 6.71E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05425 bb5ea311a5fe20b70991bc35d863d3b9 159 Pfam PF13671 AAA domain 3 142 3.3E-26 T 28-03-2018 AFA_RS05425 bb5ea311a5fe20b70991bc35d863d3b9 159 Gene3D G3DSA:3.40.50.300 1 156 2.7E-14 T 28-03-2018 AFA_RS02010 7dc3a37239ee6eae8e8fefeeb85c3f2f 296 PIRSF PIRSF026649 1 296 6.9E-77 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFA_RS02010 7dc3a37239ee6eae8e8fefeeb85c3f2f 296 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 23 287 2.4E-59 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 SUPERFAMILY SSF46785 1 82 7.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 Gene3D G3DSA:1.10.10.10 1 83 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 Pfam PF03466 LysR substrate binding domain 90 288 6.6E-35 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 Gene3D G3DSA:3.40.190.10 88 176 5.6E-18 T 28-03-2018 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 Gene3D G3DSA:3.40.190.10 177 266 1.4E-15 T 28-03-2018 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 SUPERFAMILY SSF53850 90 294 3.21E-32 T 28-03-2018 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.6E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08550 a123da49b1b41798cf3320e9a0b1ae5d 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05700 dea21238c9d424ce96c39ca98ed772aa 560 Gene3D G3DSA:3.40.720.10 17 458 7.1E-113 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS05700 dea21238c9d424ce96c39ca98ed772aa 560 Pfam PF00884 Sulfatase 21 429 8.1E-77 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS05700 dea21238c9d424ce96c39ca98ed772aa 560 ProSitePatterns PS00149 Sulfatases signature 2. 121 131 - T 28-03-2018 IPR024607 Sulfatase, conserved site AFA_RS05700 dea21238c9d424ce96c39ca98ed772aa 560 Gene3D G3DSA:3.30.1120.10 459 541 6.5E-19 T 28-03-2018 AFA_RS05700 dea21238c9d424ce96c39ca98ed772aa 560 SUPERFAMILY SSF53649 19 533 5.96E-150 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS16700 fe4b3eeb25f2b9d6b8145d23668d5daf 254 Gene3D G3DSA:3.40.50.150 24 193 1.8E-15 T 28-03-2018 AFA_RS16700 fe4b3eeb25f2b9d6b8145d23668d5daf 254 SUPERFAMILY SSF53335 20 166 4.8E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16700 fe4b3eeb25f2b9d6b8145d23668d5daf 254 Pfam PF13649 Methyltransferase domain 50 132 1.6E-6 T 28-03-2018 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 SUPERFAMILY SSF52540 82 359 2.02E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Gene3D G3DSA:2.40.10.170 1 80 7.4E-27 T 28-03-2018 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 SUPERFAMILY SSF47917 357 472 3.14E-53 T 28-03-2018 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 76 6.9E-17 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 472 55.886 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 SUPERFAMILY SSF50615 3 80 2.12E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Gene3D G3DSA:3.40.50.300 81 359 2.7E-86 T 28-03-2018 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 471 1.7E-243 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 SMART SM00382 147 339 0.0037 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 354 8.5E-59 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16600 3a1ca521295faa085726e66919809fc5 473 Gene3D G3DSA:1.10.1140.10 360 470 1.6E-43 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS14205 4d14564f42069804e6ffa9845cf97300 724 Gene3D G3DSA:3.40.720.10 120 455 4.5E-21 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS14205 4d14564f42069804e6ffa9845cf97300 724 Pfam PF04185 Phosphoesterase family 46 451 1.9E-113 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 AFA_RS14205 4d14564f42069804e6ffa9845cf97300 724 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 719 1.0E-295 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS14205 4d14564f42069804e6ffa9845cf97300 724 Pfam PF05506 Domain of unknown function (DUF756) 623 705 3.6E-24 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS14205 4d14564f42069804e6ffa9845cf97300 724 Pfam PF05506 Domain of unknown function (DUF756) 523 611 8.4E-26 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS02535 d8bf9e54f6be3d19e0bec2ae0f324080 278 Pfam PF07883 Cupin domain 72 141 4.0E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS02535 d8bf9e54f6be3d19e0bec2ae0f324080 278 Pfam PF07883 Cupin domain 195 254 1.4E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS02535 d8bf9e54f6be3d19e0bec2ae0f324080 278 SUPERFAMILY SSF51182 19 271 3.3E-79 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS02535 d8bf9e54f6be3d19e0bec2ae0f324080 278 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 6 272 4.9E-119 T 28-03-2018 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 AFA_RS02535 d8bf9e54f6be3d19e0bec2ae0f324080 278 Gene3D G3DSA:2.60.120.10 12 272 6.4E-49 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 282 295 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 SMART SM00382 103 283 5.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 SMART SM00963 1 86 1.1E-32 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.481 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 SUPERFAMILY SSF52540 42 370 5.84E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Pfam PF02978 Signal peptide binding domain 341 441 6.2E-32 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Pfam PF00448 SRP54-type protein, GTPase domain 105 308 5.9E-69 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Gene3D G3DSA:3.40.50.300 103 221 3.7E-17 T 28-03-2018 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Gene3D G3DSA:1.20.120.140 1 90 4.4E-26 T 28-03-2018 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 SMART SM00962 104 309 6.7E-114 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.7E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Gene3D G3DSA:1.10.260.30 341 446 2.3E-36 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 SUPERFAMILY SSF47446 341 445 5.4E-35 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 443 1.7E-171 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 AFA_RS02425 ead1e759c69228ba506650cc48c90028 474 Gene3D G3DSA:1.20.120.140 222 323 5.7E-33 T 28-03-2018 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 7.7E-186 T 28-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 328 3.4E-99 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 PIRSF PIRSF001359 1 329 1.8E-87 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 SUPERFAMILY SSF51569 1 329 2.78E-110 T 28-03-2018 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 Gene3D G3DSA:3.20.20.70 1 331 1.8E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFA_RS03425 3a5d9dadfb37d01f3597a74d6afea74f 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 3.3E-104 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFA_RS12470 fd17a942552536cb3acecd308df4263c 191 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 7.7E-23 T 28-03-2018 IPR001727 Gdt1 family AFA_RS12470 fd17a942552536cb3acecd308df4263c 191 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 8.4E-21 T 28-03-2018 IPR001727 Gdt1 family AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 SUPERFAMILY SSF54373 271 361 2.75E-9 T 28-03-2018 AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 Gene3D G3DSA:3.50.50.60 1 415 1.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 Pfam PF01266 FAD dependent oxidoreductase 2 399 6.3E-59 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 SUPERFAMILY SSF51905 107 271 7.77E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 SUPERFAMILY SSF51905 361 414 7.77E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00995 dca59eaa27832bdb1de7d128aa424873 415 SUPERFAMILY SSF51905 1 54 7.77E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18215 92b3b866473cc04a449cab8251c4db29 186 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 104 5.3E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS18215 92b3b866473cc04a449cab8251c4db29 186 SUPERFAMILY SSF69118 1 183 8.9E-45 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS18215 92b3b866473cc04a449cab8251c4db29 186 Gene3D G3DSA:1.20.5.810 10 42 1.4E-9 T 28-03-2018 AFA_RS18215 92b3b866473cc04a449cab8251c4db29 186 Gene3D G3DSA:1.20.1290.10 43 182 6.3E-21 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS18215 92b3b866473cc04a449cab8251c4db29 186 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 119 1.4E-10 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 SUPERFAMILY SSF50129 1 140 7.15E-39 T 28-03-2018 IPR011032 GroES-like AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 Gene3D G3DSA:3.40.50.720 134 308 2.7E-39 T 28-03-2018 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 Pfam PF00107 Zinc-binding dehydrogenase 151 277 3.0E-25 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 SUPERFAMILY SSF51735 111 286 4.05E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 Gene3D G3DSA:3.90.180.10 1 133 9.3E-40 T 28-03-2018 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 SMART SM00829 10 322 8.3E-45 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 1.3E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS13445 5f2b4795ded2ce0ead1e39373648499f 324 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 1.0E-142 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 Gene3D G3DSA:3.60.21.10 5 346 7.7E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 PRINTS PR00114 Serine/threonine phosphatase family signature 13 40 6.2E-5 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 PRINTS PR00114 Serine/threonine phosphatase family signature 48 75 6.2E-5 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 SUPERFAMILY SSF56300 217 274 1.82E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 SUPERFAMILY SSF56300 11 151 1.82E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS18430 0aabb0b706a22ccbd927155781b734e8 352 Pfam PF00149 Calcineurin-like phosphoesterase 15 148 1.8E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 PIRSF PIRSF039085 1 243 1.9E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 SUPERFAMILY SSF52540 4 238 6.88E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 Gene3D G3DSA:3.40.50.300 1 243 1.1E-74 T 28-03-2018 AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 SMART SM00382 29 216 6.7E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01670 e3bdbd5b5e4fa1b4c32cd5ae538f5399 243 Pfam PF00005 ABC transporter 20 168 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 144 1.8E-7 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 Pfam PF09130 Domain of unknown function (DUF1932) 195 263 4.4E-7 T 28-03-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 Gene3D G3DSA:3.40.50.720 9 174 3.3E-16 T 28-03-2018 AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 Gene3D G3DSA:1.10.1040.10 177 291 5.4E-20 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 SUPERFAMILY SSF51735 9 161 6.59E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS03715 9cbf1ea83b4bbd75fc37d6faea5c1e4c 297 SUPERFAMILY SSF48179 168 268 2.72E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 SUPERFAMILY SSF52402 257 366 2.34E-6 T 28-03-2018 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:3.30.565.10 710 878 2.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 771 875 1.2E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 SMART SM00387 768 878 4.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:1.20.120.620 398 496 9.2E-24 T 28-03-2018 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Pfam PF13493 Domain of unknown function (DUF4118) 401 503 1.0E-27 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:3.30.450.40 497 649 4.1E-5 T 28-03-2018 IPR029016 GAF domain-like AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:3.40.50.300 24 153 3.1E-22 T 28-03-2018 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 SUPERFAMILY SSF47384 652 724 9.42E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 PRINTS PR00344 Bacterial sensor protein C-terminal signature 805 819 9.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 PRINTS PR00344 Bacterial sensor protein C-terminal signature 823 833 9.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 PRINTS PR00344 Bacterial sensor protein C-terminal signature 838 856 9.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 PRINTS PR00344 Bacterial sensor protein C-terminal signature 862 875 9.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 SUPERFAMILY SSF55874 714 880 1.03E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:1.10.287.130 650 709 3.3E-14 T 28-03-2018 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Gene3D G3DSA:3.40.50.620 229 368 2.7E-11 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Pfam PF00512 His Kinase A (phospho-acceptor) domain 658 723 7.4E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 SMART SM00388 657 724 3.9E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS07310 877aad4e0af6f5267ce6ae9422ecc29b 889 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 24 233 4.6E-91 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 AFA_RS15100 636fd8024a6a248b908e85845118526b 104 Pfam PF00355 Rieske [2Fe-2S] domain 2 89 2.5E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS15100 636fd8024a6a248b908e85845118526b 104 Gene3D G3DSA:2.102.10.10 1 102 2.3E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS15100 636fd8024a6a248b908e85845118526b 104 SUPERFAMILY SSF50022 2 100 1.57E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 11 217 1.9E-73 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 SUPERFAMILY SSF54782 226 314 4.58E-26 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 SUPERFAMILY SSF53850 10 224 8.25E-78 T 28-03-2018 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PIRSF PIRSF001438 3 315 1.5E-114 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 232 300 3.6E-19 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 10 302 36.814 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 236 252 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Gene3D G3DSA:3.30.160.40 226 309 5.1E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Gene3D G3DSA:3.40.190.10 112 204 1.3E-35 T 28-03-2018 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 Gene3D G3DSA:3.40.190.10 3 111 5.9E-44 T 28-03-2018 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PRINTS PR00151 Porphobilinogen deaminase signature 81 100 2.1E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PRINTS PR00151 Porphobilinogen deaminase signature 129 146 2.1E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PRINTS PR00151 Porphobilinogen deaminase signature 235 252 2.1E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PRINTS PR00151 Porphobilinogen deaminase signature 50 70 2.1E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 PRINTS PR00151 Porphobilinogen deaminase signature 148 165 2.1E-45 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10965 582f48563736cce7c91a81ad4e0c7bb6 320 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 11 302 1.8E-105 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS12235 25577b20026375546850fe496e27f68a 974 SUPERFAMILY SSF55464 3 297 2.2E-74 T 28-03-2018 AFA_RS12235 25577b20026375546850fe496e27f68a 974 Pfam PF08751 TrwC relaxase 13 292 2.6E-75 T 28-03-2018 IPR014862 TrwC relaxase AFA_RS12235 25577b20026375546850fe496e27f68a 974 Pfam PF13604 AAA domain 480 663 1.4E-42 T 28-03-2018 AFA_RS12235 25577b20026375546850fe496e27f68a 974 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 17 297 1.9E-77 T 28-03-2018 IPR014059 Conjugative relaxase, N-terminal AFA_RS12235 25577b20026375546850fe496e27f68a 974 Gene3D G3DSA:3.40.50.300 349 667 1.2E-20 T 28-03-2018 AFA_RS12235 25577b20026375546850fe496e27f68a 974 SUPERFAMILY SSF52540 588 651 6.91E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12235 25577b20026375546850fe496e27f68a 974 SUPERFAMILY SSF52540 817 932 6.91E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12235 25577b20026375546850fe496e27f68a 974 SUPERFAMILY SSF52540 701 735 6.91E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12235 25577b20026375546850fe496e27f68a 974 SUPERFAMILY SSF52540 476 617 2.96E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 PIRSF PIRSF000148 2 374 4.1E-61 T 28-03-2018 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 357 4.6E-54 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 Gene3D G3DSA:3.30.360.10 146 354 3.0E-56 T 28-03-2018 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 SUPERFAMILY SSF51735 4 148 2.25E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 SUPERFAMILY SSF55347 135 358 4.37E-73 T 28-03-2018 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 265 279 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 4 369 1.3E-182 T 28-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 Gene3D G3DSA:3.40.50.720 1 145 5.9E-17 T 28-03-2018 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 122 3.3E-21 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 371 32.012 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AFA_RS10790 c5a6b115659215656e482a283e6fd1bd 374 SMART SM00859 4 123 8.7E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Pfam PF00873 AcrB/AcrD/AcrF family 8 1010 1.6E-152 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82693 142 186 3.19E-11 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82693 272 328 3.19E-11 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:1.20.1640.10 796 1014 2.3E-37 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82714 189 270 4.58E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82866 794 1014 4.45E-44 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 3.9E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 3.9E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 3.9E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 3.9E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 3.9E-19 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82866 303 492 4.71E-33 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:1.20.1640.10 299 501 2.5E-28 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:3.30.2090.10 708 795 5.8E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82693 556 651 8.63E-10 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:3.30.70.1430 44 148 8.8E-26 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:3.30.2090.10 185 271 2.3E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82714 709 793 1.11E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 SUPERFAMILY SSF82693 44 138 1.92E-17 T 28-03-2018 AFA_RS03150 3425b2f823e69d34517a3a70e4f9fafd 1023 Gene3D G3DSA:3.30.70.1430 557 659 2.3E-15 T 28-03-2018 AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 Gene3D G3DSA:3.40.50.720 1 42 1.0E-12 T 28-03-2018 AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 Gene3D G3DSA:3.40.50.720 43 252 1.3E-63 T 28-03-2018 AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 1.7E-64 T 28-03-2018 AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 SUPERFAMILY SSF51735 4 251 9.28E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS03415 19952324ddbd7dd874b50a273dec94f8 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 Gene3D G3DSA:1.10.287.950 338 535 1.5E-36 T 28-03-2018 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 Gene3D G3DSA:1.10.287.950 135 337 7.1E-9 T 28-03-2018 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 4.3E-34 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 4.3E-34 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 488 4.3E-34 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 4.3E-34 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 SMART SM00283 284 531 6.3E-56 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 497 9.9E-36 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS07755 4fd394da83fbf7543d5166c34242c277 569 SUPERFAMILY SSF58104 252 532 2.49E-55 T 28-03-2018 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SMART SM00831 23 96 1.7E-19 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Pfam PF00122 E1-E2 ATPase 150 349 4.1E-45 T 28-03-2018 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Pfam PF00702 haloacid dehalogenase-like hydrolase 365 654 3.4E-19 T 28-03-2018 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF56784 367 387 1.65E-36 T 28-03-2018 IPR023214 HAD-like domain AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF56784 494 739 1.65E-36 T 28-03-2018 IPR023214 HAD-like domain AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 27 899 0.0 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Gene3D G3DSA:2.70.150.10 32 271 8.5E-42 T 28-03-2018 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 371 377 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF81665 270 363 2.75E-100 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF81665 27 145 2.75E-100 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF81665 689 897 2.75E-100 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 SUPERFAMILY SSF81653 151 269 1.57E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Gene3D G3DSA:1.20.1110.10 533 895 6.1E-53 T 28-03-2018 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Pfam PF00689 Cation transporting ATPase, C-terminus 723 891 1.7E-17 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Pfam PF00690 Cation transporter/ATPase, N-terminus 27 91 3.9E-15 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 748 761 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 403 416 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 299 318 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 282 298 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 698 713 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 716 727 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 803 824 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 853 874 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 PRINTS PR01836 Magnesium-transporting ATPase signature 768 784 1.7E-86 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 Gene3D G3DSA:3.40.1110.10 324 532 1.4E-39 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 262 408 8.9E-22 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS15570 6567fc5ea8381755ec5369c90c7ccbac 900 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 611 729 3.5E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 SUPERFAMILY SSF55073 367 516 1.49E-47 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 Gene3D G3DSA:3.30.70.270 358 525 4.6E-51 T 28-03-2018 AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 515 9.0E-45 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 SMART SM00267 348 516 1.4E-51 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 SUPERFAMILY SSF103190 67 180 1.1E-7 T 28-03-2018 IPR029151 Periplasmic sensor domain-like AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 Pfam PF02743 Cache domain 40 264 3.5E-21 T 28-03-2018 IPR033479 Double Cache domain 1 AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 Gene3D G3DSA:3.30.450.20 34 160 1.1E-11 T 28-03-2018 AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 Pfam PF00990 Diguanylate cyclase, GGDEF domain 363 512 2.2E-42 T 28-03-2018 IPR000160 GGDEF domain AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 Gene3D G3DSA:3.30.450.20 161 278 1.3E-16 T 28-03-2018 AFA_RS17370 f8a142cbbc36a873477f9709d6c45c7c 529 SUPERFAMILY SSF103190 185 263 3.85E-11 T 28-03-2018 IPR029151 Periplasmic sensor domain-like AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.4E-31 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SMART SM00382 170 349 6.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SMART SM00357 52 118 5.7E-17 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 1.6E-209 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SUPERFAMILY SSF52540 90 371 9.48E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SUPERFAMILY SSF68912 1 46 7.45E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SUPERFAMILY SSF50249 49 125 2.51E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 SMART SM00959 5 47 8.1E-18 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 3.7E-24 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Gene3D G3DSA:3.40.50.300 129 418 1.3E-58 T 28-03-2018 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 8.0E-16 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Gene3D G3DSA:2.40.50.140 2 126 1.2E-45 T 28-03-2018 AFA_RS11690 5a858303673a90c0c9474fefdb502c3b 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 242.579 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 Gene3D G3DSA:3.40.190.10 281 411 2.0E-14 T 28-03-2018 AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 167 593 2.4E-49 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 Gene3D G3DSA:3.10.105.10 412 651 1.7E-40 T 28-03-2018 AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 SUPERFAMILY SSF53850 168 665 3.08E-78 T 28-03-2018 AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 SUPERFAMILY SSF53850 32 132 3.08E-78 T 28-03-2018 AFA_RS04725 2addaf716bca65ddc2801716a0cf8bcf 728 Gene3D G3DSA:3.90.76.10 46 280 2.9E-23 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Gene3D G3DSA:3.50.50.60 1 98 3.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 296 1.6E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 SUPERFAMILY SSF51905 1 306 8.25E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Gene3D G3DSA:3.30.390.30 316 417 1.8E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Gene3D G3DSA:3.50.50.60 99 231 6.9E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Pfam PF14759 Reductase C-terminal 315 399 1.4E-18 T 28-03-2018 IPR028202 Reductase, C-terminal AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 98 107 2.2E-13 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 165 2.2E-13 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 241 2.2E-13 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 2.2E-13 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.3E-19 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 14 4.3E-19 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 4.3E-19 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 4.3E-19 T 28-03-2018 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 Gene3D G3DSA:3.50.50.60 236 315 5.7E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13925 eaff98c9c7d01ce30d8127197d6c2215 425 SUPERFAMILY SSF55424 312 402 2.2E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 SMART SM00382 66 237 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11005 f3770632244ac32fdce364644c42296a 337 Gene3D G3DSA:3.30.250.10 278 335 2.5E-27 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFA_RS11005 f3770632244ac32fdce364644c42296a 337 SUPERFAMILY SSF52540 13 276 2.01E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11005 f3770632244ac32fdce364644c42296a 337 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 12 333 4.0E-172 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 SUPERFAMILY SSF54752 277 335 2.62E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 174 203 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 102 131 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 136 165 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 219 247 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 252 281 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 PRINTS PR00142 RecA protein signature 306 323 1.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 Pfam PF00154 recA bacterial DNA recombination protein 15 277 3.1E-144 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 ProSitePatterns PS00321 recA signature. 222 230 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 Hamap MF_00268 Protein RecA [recA]. 13 337 50.697 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFA_RS11005 f3770632244ac32fdce364644c42296a 337 Gene3D G3DSA:3.40.50.300 34 277 8.8E-47 T 28-03-2018 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Gene3D G3DSA:1.10.439.10 29 176 2.4E-38 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Gene3D G3DSA:1.10.1400.10 567 710 5.1E-21 T 28-03-2018 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Gene3D G3DSA:3.60.20.10 356 566 1.9E-32 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Gene3D G3DSA:1.10.287.150 180 221 9.5E-16 T 28-03-2018 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 PIRSF PIRSF001227 17 809 3.1E-105 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Pfam PF01804 Penicillin amidase 34 799 7.0E-129 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 SUPERFAMILY SSF56235 33 230 4.12E-170 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 SUPERFAMILY SSF56235 257 809 4.12E-170 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS15005 6a8418ca1ca4d85b3a9c1888d8df85f2 810 Gene3D G3DSA:3.60.20.10 222 346 3.0E-19 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS08135 7003551444ac899f5944739dedfbea72 292 SUPERFAMILY SSF56925 167 291 1.33E-7 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS15135 386fb1f6af82d56731053424e5654a41 323 SUPERFAMILY SSF51556 7 321 1.76E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS15135 386fb1f6af82d56731053424e5654a41 323 Pfam PF04909 Amidohydrolase 41 320 4.0E-46 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS15135 386fb1f6af82d56731053424e5654a41 323 Gene3D G3DSA:3.20.20.140 2 320 2.0E-53 T 28-03-2018 AFA_RS16740 0fad002f15d714b5f50ae352a91a6fe3 507 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 445 3.7E-143 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 PRINTS PR01270 Histone deacetylase superfamily signature 258 268 1.3E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 PRINTS PR01270 Histone deacetylase superfamily signature 139 162 1.3E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 PRINTS PR01270 Histone deacetylase superfamily signature 173 188 1.3E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 Gene3D G3DSA:3.40.800.20 14 363 3.2E-105 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 Pfam PF00850 Histone deacetylase domain 47 327 7.0E-78 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS08300 548d4337bf59dac14769711b6fef494a 369 SUPERFAMILY SSF52768 3 331 5.28E-98 T 28-03-2018 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Gene3D G3DSA:1.20.910.10 408 636 1.4E-29 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 285 359 5.6E-9 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 SUPERFAMILY SSF53901 6 199 9.29E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 SUPERFAMILY SSF48613 419 631 4.59E-27 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Gene3D G3DSA:3.40.47.10 3 191 4.2E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 128 199 1.3E-4 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 SUPERFAMILY SSF53901 255 369 1.39E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Gene3D G3DSA:3.40.47.10 192 375 6.3E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS01585 4b25cd6bc233be9a013d9d30266250e7 636 Pfam PF14518 Iron-containing redox enzyme 509 624 2.7E-9 T 28-03-2018 IPR028201 PqqC-like protein AFA_RS18160 e65dff8d9e68897c81587adaa3f4dea1 441 Gene3D G3DSA:2.40.160.60 30 441 4.1E-93 T 28-03-2018 AFA_RS18160 e65dff8d9e68897c81587adaa3f4dea1 441 SUPERFAMILY SSF56935 30 441 7.32E-96 T 28-03-2018 AFA_RS18160 e65dff8d9e68897c81587adaa3f4dea1 441 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 23 441 2.7E-110 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 282 37.726 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 7.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 7.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 7.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 7.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 7.0E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 284 2.8E-127 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 SUPERFAMILY SSF52096 26 284 3.4E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 Pfam PF01039 Carboxyl transferase domain 93 241 3.6E-14 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 AFA_RS13180 d0908c6ee4380a2f6894814b12792d3f 292 Gene3D G3DSA:3.90.226.10 13 291 8.7E-68 T 28-03-2018 AFA_RS13670 dc1abd40933d37b1d09092c351f8e981 444 Pfam PF00437 Type II/IV secretion system protein 82 358 7.5E-76 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AFA_RS13670 dc1abd40933d37b1d09092c351f8e981 444 Gene3D G3DSA:3.30.450.90 76 181 5.2E-33 T 28-03-2018 AFA_RS13670 dc1abd40933d37b1d09092c351f8e981 444 Gene3D G3DSA:3.40.50.300 182 436 8.5E-20 T 28-03-2018 AFA_RS13670 dc1abd40933d37b1d09092c351f8e981 444 SUPERFAMILY SSF52540 62 396 2.67E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13390 444b39d811221578ef0108355a85499d 776 SMART SM00929 83 123 5.8E-21 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 76 3.0E-20 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 SUPERFAMILY SSF50692 708 773 1.33E-7 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS13390 444b39d811221578ef0108355a85499d 776 Gene3D G3DSA:3.10.20.30 1 170 2.5E-16 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS13390 444b39d811221578ef0108355a85499d 776 SUPERFAMILY SSF54862 144 203 9.77E-7 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Gene3D G3DSA:3.40.50.740 274 413 1.7E-25 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 SUPERFAMILY SSF54292 1 124 1.11E-33 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Gene3D G3DSA:3.40.50.740 436 639 1.4E-23 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Pfam PF00384 Molybdopterin oxidoreductase 273 631 2.7E-31 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Pfam PF01568 Molydopterin dinucleotide binding domain 706 772 2.9E-8 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 AFA_RS13390 444b39d811221578ef0108355a85499d 776 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 631 9.1E-199 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 122 4.8E-17 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13390 444b39d811221578ef0108355a85499d 776 SUPERFAMILY SSF53706 214 423 3.99E-83 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 SUPERFAMILY SSF53706 458 655 3.99E-83 T 28-03-2018 AFA_RS13390 444b39d811221578ef0108355a85499d 776 Gene3D G3DSA:2.40.40.20 692 775 1.1E-9 T 28-03-2018 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SUPERFAMILY SSF54909 77 153 6.3E-8 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Gene3D G3DSA:1.10.10.10 168 226 2.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SUPERFAMILY SSF46785 16 86 1.14E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Pfam PF09339 IclR helix-turn-helix domain 191 226 1.2E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Gene3D G3DSA:3.30.70.920 232 324 5.1E-13 T 28-03-2018 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Gene3D G3DSA:3.30.70.920 68 162 7.1E-11 T 28-03-2018 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SUPERFAMILY SSF54909 239 318 1.23E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 207 226 8.4E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 180 196 8.4E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 196 207 8.4E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Pfam PF01037 Lrp/AsnC ligand binding domain 84 151 4.2E-6 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Pfam PF01037 Lrp/AsnC ligand binding domain 245 315 2.1E-6 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Pfam PF13404 AsnC-type helix-turn-helix domain 16 56 5.6E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 199 217 - T 28-03-2018 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 Gene3D G3DSA:1.10.10.10 14 64 2.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SUPERFAMILY SSF46785 173 230 5.57E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SMART SM00344 180 285 8.0E-5 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS08430 ae70233ab2bb05b66b89d6a592cc857e 332 SMART SM00344 16 121 1.2E-13 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 213 33.412 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 SUPERFAMILY SSF52317 3 213 1.68E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 212 2.6E-58 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 PIRSF PIRSF000495 2 215 2.6E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 Gene3D G3DSA:3.40.50.880 1 214 7.3E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS17150 b7fceb9a8eab02d96a2791783fbe3130 215 Pfam PF00117 Glutamine amidotransferase class-I 6 209 7.0E-13 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 Pfam PF13411 MerR HTH family regulatory protein 6 70 6.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 Gene3D G3DSA:1.10.1660.10 59 135 6.4E-10 T 28-03-2018 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 Gene3D G3DSA:1.10.1660.10 1 58 1.2E-15 T 28-03-2018 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 SUPERFAMILY SSF46955 5 123 7.33E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00335 fb629a7e7d6004bc342f472e14393b2b 146 SMART SM00422 4 72 2.5E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS17635 b485cbacec4663b88148c612d7ecfd26 314 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 90 112 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site AFA_RS17635 b485cbacec4663b88148c612d7ecfd26 314 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 28 311 25.057 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AFA_RS17635 b485cbacec4663b88148c612d7ecfd26 314 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 33 309 4.7E-89 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AFA_RS17635 b485cbacec4663b88148c612d7ecfd26 314 Pfam PF01040 UbiA prenyltransferase family 52 297 6.5E-50 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Pfam PF00501 AMP-binding enzyme 10 422 4.2E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 512 6.4E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Gene3D G3DSA:3.40.50.980 172 327 3.3E-29 T 28-03-2018 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Gene3D G3DSA:2.30.38.10 328 415 2.8E-21 T 28-03-2018 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 SUPERFAMILY SSF56801 4 527 3.01E-114 T 28-03-2018 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Gene3D G3DSA:3.40.50.980 3 171 4.4E-32 T 28-03-2018 AFA_RS00310 b7f8a41ab9afd67fef11b59ee50714b1 543 Gene3D G3DSA:3.30.300.30 417 532 3.3E-23 T 28-03-2018 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 SUPERFAMILY SSF63882 1 170 9.94E-50 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Gene3D G3DSA:3.90.105.10 21 54 1.6E-12 T 28-03-2018 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Gene3D G3DSA:2.40.340.10 327 393 2.9E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Gene3D G3DSA:2.170.190.11 55 135 2.0E-23 T 28-03-2018 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 SUPERFAMILY SSF63867 326 397 5.49E-14 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 SUPERFAMILY SSF53218 171 316 4.58E-43 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Pfam PF00994 Probable molybdopterin binding domain 174 311 1.6E-30 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 307 8.3E-30 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 SMART SM00852 174 312 5.1E-43 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Pfam PF03454 MoeA C-terminal region (domain IV) 329 393 2.8E-13 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Gene3D G3DSA:3.40.980.10 144 319 2.0E-55 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 281 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFA_RS03070 aae348179bf4dc00bffc7ea1751f237b 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 161 4.5E-41 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS11265 befabfe5f45758d367fe6638d0e0f7c9 114 SUPERFAMILY SSF46626 40 113 3.58E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11265 befabfe5f45758d367fe6638d0e0f7c9 114 Pfam PF00034 Cytochrome c 48 113 1.0E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11265 befabfe5f45758d367fe6638d0e0f7c9 114 Gene3D G3DSA:1.10.760.10 13 113 5.2E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 Pfam PF03466 LysR substrate binding domain 100 303 4.6E-25 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 SUPERFAMILY SSF46785 12 99 1.76E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 Gene3D G3DSA:3.40.190.10 92 215 1.8E-15 T 28-03-2018 AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 SUPERFAMILY SSF53850 101 306 7.42E-24 T 28-03-2018 AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 Gene3D G3DSA:1.10.10.10 7 91 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14180 7203b9096ce938bfaa3fb6c577236a5d 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 74 8.1E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 44 446 3.0E-90 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 Gene3D G3DSA:3.20.20.140 93 410 1.9E-93 T 28-03-2018 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 Gene3D G3DSA:2.30.40.10 24 92 2.0E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 SUPERFAMILY SSF51338 25 77 8.48E-29 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 SUPERFAMILY SSF51338 389 452 8.48E-29 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 Pfam PF01979 Amidohydrolase family 75 442 2.2E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 ProSitePatterns PS00483 Dihydroorotase signature 2. 325 336 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS08025 4e189216d745e1d539a6d65b4d9f7181 464 SUPERFAMILY SSF51556 78 390 1.04E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS00505 9175fef4a43d0991a936a2c3caa6bfe2 474 SUPERFAMILY SSF51679 5 439 8.37E-126 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS00505 9175fef4a43d0991a936a2c3caa6bfe2 474 PIRSF PIRSF000337 5 448 1.9E-141 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS00505 9175fef4a43d0991a936a2c3caa6bfe2 474 Gene3D G3DSA:3.20.20.30 4 460 3.5E-115 T 28-03-2018 AFA_RS00505 9175fef4a43d0991a936a2c3caa6bfe2 474 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 435 8.2E-165 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS00505 9175fef4a43d0991a936a2c3caa6bfe2 474 Pfam PF00296 Luciferase-like monooxygenase 31 391 2.4E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS05200 345c2d2dddcc854b2c3134ced1bcce13 105 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.658 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 AFA_RS05200 345c2d2dddcc854b2c3134ced1bcce13 105 SUPERFAMILY SSF50249 1 95 2.74E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS05200 345c2d2dddcc854b2c3134ced1bcce13 105 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 2.2E-29 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 AFA_RS05200 345c2d2dddcc854b2c3134ced1bcce13 105 PIRSF PIRSF003135 1 95 7.4E-18 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 AFA_RS05200 345c2d2dddcc854b2c3134ced1bcce13 105 Gene3D G3DSA:2.40.50.140 1 98 7.4E-4 T 28-03-2018 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 Gene3D G3DSA:2.40.30.10 326 431 8.3E-21 T 28-03-2018 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 SUPERFAMILY SSF50447 231 320 8.25E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 Gene3D G3DSA:2.40.30.10 230 323 1.4E-13 T 28-03-2018 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 17 429 1.1E-157 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 Gene3D G3DSA:3.40.50.300 11 229 3.8E-36 T 28-03-2018 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 Pfam PF00009 Elongation factor Tu GTP binding domain 17 221 2.7E-37 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 SUPERFAMILY SSF52540 16 247 4.25E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 PRINTS PR00315 GTP-binding elongation factor signature 78 86 1.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 PRINTS PR00315 GTP-binding elongation factor signature 98 108 1.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 PRINTS PR00315 GTP-binding elongation factor signature 114 125 1.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS14745 a91643e506857f23bad75ac7af39fdf8 433 SUPERFAMILY SSF50465 327 430 4.8E-28 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFA_RS04500 08044d44e41b82af022415414b4bd5ad 426 SUPERFAMILY SSF75304 11 411 3.4E-99 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS04500 08044d44e41b82af022415414b4bd5ad 426 Gene3D G3DSA:3.90.1300.10 3 416 2.1E-97 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS04500 08044d44e41b82af022415414b4bd5ad 426 Pfam PF01425 Amidase 304 404 1.0E-6 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS04500 08044d44e41b82af022415414b4bd5ad 426 Pfam PF01425 Amidase 19 210 5.2E-65 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS13620 091888537c46a6a6bc20b11939e51969 285 Gene3D G3DSA:3.40.50.300 3 215 3.3E-31 T 28-03-2018 AFA_RS13620 091888537c46a6a6bc20b11939e51969 285 SMART SM00382 29 188 3.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13620 091888537c46a6a6bc20b11939e51969 285 SUPERFAMILY SSF52540 11 255 2.23E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13620 091888537c46a6a6bc20b11939e51969 285 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 33 179 3.4E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS08030 3933fba3b6dd7234285ab189b78543f5 152 Pfam PF01475 Ferric uptake regulator family 9 126 3.6E-41 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFA_RS08030 3933fba3b6dd7234285ab189b78543f5 152 SUPERFAMILY SSF46785 5 132 5.45E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08030 3933fba3b6dd7234285ab189b78543f5 152 Gene3D G3DSA:1.10.10.10 3 89 2.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07735 fd5836ff5fcc0c2bd2d8569779a4e6cb 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 318 1.7E-56 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS07735 fd5836ff5fcc0c2bd2d8569779a4e6cb 334 PIRSF PIRSF017082 3 333 1.9E-65 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS07735 fd5836ff5fcc0c2bd2d8569779a4e6cb 334 SUPERFAMILY SSF53850 128 294 3.62E-8 T 28-03-2018 AFA_RS07735 fd5836ff5fcc0c2bd2d8569779a4e6cb 334 Gene3D G3DSA:3.40.190.10 133 329 6.8E-7 T 28-03-2018 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 18 391 2.2E-122 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 Pfam PF01546 Peptidase family M20/M25/M40 80 392 3.3E-36 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 SUPERFAMILY SSF55031 187 290 4.78E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 SUPERFAMILY SSF53187 11 186 1.23E-56 T 28-03-2018 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 SUPERFAMILY SSF53187 313 393 1.23E-56 T 28-03-2018 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 Gene3D G3DSA:3.30.70.360 190 305 2.1E-25 T 28-03-2018 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 Pfam PF07687 Peptidase dimerisation domain 183 290 1.8E-25 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 Gene3D G3DSA:3.40.630.10 306 396 1.3E-8 T 28-03-2018 AFA_RS18505 ad9d55f68ecf5a8799aecfe678d1e546 398 Gene3D G3DSA:3.40.630.10 8 189 1.0E-29 T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 Gene3D G3DSA:3.40.50.2300 176 315 4.9E-31 T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 Gene3D G3DSA:3.40.50.2300 58 175 2.7E-31 T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 Gene3D G3DSA:1.10.260.40 4 57 6.4E-21 T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 SUPERFAMILY SSF53822 60 327 6.87E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 SMART SM00354 3 73 2.3E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 Pfam PF13377 Periplasmic binding protein-like domain 170 345 2.6E-28 T 28-03-2018 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 SUPERFAMILY SSF47413 3 61 1.21E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS07280 e0d0e137f1c8e2d8e5e6facae08d1255 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 1.3E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 Pfam PF00410 Ribosomal protein S8 5 130 7.4E-51 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 Gene3D G3DSA:3.30.1490.10 75 130 1.1E-21 T 28-03-2018 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.696 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 Gene3D G3DSA:3.30.1370.30 1 67 3.8E-27 T 28-03-2018 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18030 2da1bb0140d96e2dc4a0dc5c99be4b4f 131 SUPERFAMILY SSF56047 2 130 4.58E-48 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Pfam PF00970 Oxidoreductase FAD-binding domain 106 197 7.7E-13 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 245 256 3.2E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 3.2E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 298 306 3.2E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 227 3.2E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 SUPERFAMILY SSF63380 102 198 1.7E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 SUPERFAMILY SSF54292 2 90 3.28E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 SUPERFAMILY SSF52343 201 331 3.27E-37 T 28-03-2018 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 5.1E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Gene3D G3DSA:3.10.20.30 1 90 5.5E-18 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Gene3D G3DSA:2.40.30.10 96 196 2.9E-20 T 28-03-2018 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Gene3D G3DSA:3.40.50.80 197 336 1.0E-28 T 28-03-2018 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Pfam PF00175 Oxidoreductase NAD-binding domain 209 312 7.1E-24 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS17800 c1cc05c1cea2c207ec3ea17ac43a2903 344 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 82 1.1E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Pfam PF12801 4Fe-4S binding domain 111 152 1.1E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Gene3D G3DSA:3.30.70.20 320 384 8.7E-4 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 375 498 8.2E-27 T 28-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 SUPERFAMILY SSF54862 188 385 1.67E-33 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 SUPERFAMILY SSF54862 120 142 1.67E-33 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Gene3D G3DSA:3.30.70.20 306 319 0.016 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Gene3D G3DSA:3.30.70.20 237 289 1.1E-10 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Gene3D G3DSA:3.30.70.20 290 305 0.18 T 28-03-2018 AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Pfam PF13746 4Fe-4S dicluster domain 234 340 4.3E-42 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 287 298 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 Gene3D G3DSA:2.60.40.10 385 498 1.0E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS11740 e3912fc95247e289aff91288320b05f6 499 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 56 494 1.3E-151 T 28-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 SUPERFAMILY SSF53137 19 132 3.92E-47 T 28-03-2018 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 PIRSF PIRSF002131 1 132 2.7E-53 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 Gene3D G3DSA:3.30.420.80 8 132 4.8E-45 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 8.2E-56 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 132 33.071 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 Pfam PF00411 Ribosomal protein S11 22 131 1.7E-50 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFA_RS17980 ab675b8dd345c9d733a42231a4180987 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 SUPERFAMILY SSF51246 310 383 5.02E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 SUPERFAMILY SSF56059 108 306 6.72E-56 T 28-03-2018 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 12 369 40.349 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 Gene3D G3DSA:3.30.1490.20 123 185 2.1E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 Pfam PF02222 ATP-grasp domain 117 286 9.7E-47 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 SUPERFAMILY SSF52440 7 105 1.22E-23 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 Gene3D G3DSA:3.30.470.20 186 385 4.4E-43 T 28-03-2018 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 Gene3D G3DSA:3.40.50.20 12 107 5.0E-20 T 28-03-2018 AFA_RS03440 ae3c7c7a12366cb799a08ec3ba13abb2 390 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 13 374 1.3E-114 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.3E-16 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 SUPERFAMILY SSF50615 10 94 4.91E-28 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 SUPERFAMILY SSF47917 383 510 7.85E-46 T 28-03-2018 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Gene3D G3DSA:2.40.30.20 3 82 1.3E-32 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 7.0E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Gene3D G3DSA:1.20.150.20 384 510 1.4E-46 T 28-03-2018 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 SUPERFAMILY SSF52540 96 381 2.45E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 PIRSF PIRSF039088 1 513 8.2E-237 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Gene3D G3DSA:3.40.50.300 83 375 7.9E-115 T 28-03-2018 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 2.9E-247 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 3.2E-73 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS16610 8c4f72bd700ec00ac6dc8fbba8233015 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.673 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS14995 205e937f84dea4f17d9c20d35a5b22f4 631 Pfam PF02653 Branched-chain amino acid transport system / permease component 351 607 7.5E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS14995 205e937f84dea4f17d9c20d35a5b22f4 631 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 291 1.2E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS14995 205e937f84dea4f17d9c20d35a5b22f4 631 Gene3D G3DSA:1.10.3470.10 316 611 2.3E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS14995 205e937f84dea4f17d9c20d35a5b22f4 631 Gene3D G3DSA:1.10.3470.10 1 302 4.6E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS13590 d9d750557de48da070d9233c3860a710 444 SUPERFAMILY SSF53474 19 409 1.79E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13590 d9d750557de48da070d9233c3860a710 444 Pfam PF00135 Carboxylesterase family 19 305 2.4E-47 T 28-03-2018 IPR002018 Carboxylesterase, type B AFA_RS13590 d9d750557de48da070d9233c3860a710 444 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 169 184 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site AFA_RS13590 d9d750557de48da070d9233c3860a710 444 Gene3D G3DSA:3.40.50.1820 8 443 3.8E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 151 172 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 Gene3D G3DSA:3.90.180.10 1 143 5.1E-31 T 28-03-2018 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 SUPERFAMILY SSF51735 118 288 8.7E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 91 3.4E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 Pfam PF13602 Zinc-binding dehydrogenase 195 335 5.0E-24 T 28-03-2018 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 SMART SM00829 10 335 1.2E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 SUPERFAMILY SSF50129 12 147 3.3E-29 T 28-03-2018 IPR011032 GroES-like AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 Gene3D G3DSA:3.40.50.720 144 301 1.7E-26 T 28-03-2018 AFA_RS15310 98ee227ce00eb415cb40ed6a1b7f89cc 340 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 338 1.2E-168 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 AFA_RS01865 eb0ad2c77864e2600a33bb80b8a28d41 125 SUPERFAMILY SSF55298 12 123 5.65E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS01865 eb0ad2c77864e2600a33bb80b8a28d41 125 Gene3D G3DSA:3.30.1330.40 6 125 8.0E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS01865 eb0ad2c77864e2600a33bb80b8a28d41 125 Pfam PF01042 Endoribonuclease L-PSP 14 119 6.6E-27 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 SUPERFAMILY SSF54373 272 365 9.94E-9 T 28-03-2018 AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 Gene3D G3DSA:3.50.50.60 2 449 1.3E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 Pfam PF01266 FAD dependent oxidoreductase 3 402 2.1E-62 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 SUPERFAMILY SSF51905 2 55 3.95E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 SUPERFAMILY SSF51905 106 272 3.95E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08390 5e74bb9a25aa2f863a7c23a933b30cb1 453 SUPERFAMILY SSF51905 365 414 3.95E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 Pfam PF02239 Cytochrome D1 heme domain 156 501 2.3E-49 T 28-03-2018 AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 Gene3D G3DSA:2.140.10.20 105 505 7.3E-53 T 28-03-2018 AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 SUPERFAMILY SSF51004 103 504 9.68E-66 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 SUPERFAMILY SSF46626 9 96 2.58E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 26 91 3.1E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11270 093fcc91e12ab1ecb4aceeca786680c0 515 Gene3D G3DSA:1.10.760.10 5 104 1.2E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 136 159 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 2.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 Gene3D G3DSA:3.30.540.10 1 155 6.3E-50 T 28-03-2018 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 SUPERFAMILY SSF56655 1 262 1.22E-80 T 28-03-2018 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 Pfam PF00459 Inositol monophosphatase family 2 252 2.9E-61 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 Gene3D G3DSA:3.40.190.80 156 263 7.7E-27 T 28-03-2018 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 3.2E-13 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR01959 SuhB family inositol monophosphatase signature 202 214 3.2E-13 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS04520 67146fe05f3664dd8a43487926a32d8d 263 PRINTS PR01959 SuhB family inositol monophosphatase signature 110 129 3.2E-13 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS12905 29af0bf3593013ca1a383967a9c000b7 94 SUPERFAMILY SSF54909 1 94 1.79E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS12905 29af0bf3593013ca1a383967a9c000b7 94 Pfam PF07045 Domain of unknown function (DUF1330) 2 94 3.0E-29 T 28-03-2018 IPR010753 Domain of unknown function DUF1330 AFA_RS12905 29af0bf3593013ca1a383967a9c000b7 94 Gene3D G3DSA:3.30.70.100 1 94 1.3E-26 T 28-03-2018 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 SMART SM00387 356 467 3.9E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Pfam PF08521 Two-component sensor kinase N-terminal 19 163 3.8E-24 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Gene3D G3DSA:1.20.5.1040 4 59 4.6E-4 T 28-03-2018 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 SUPERFAMILY SSF55874 315 461 4.58E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 463 6.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 303 1.7E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 SUPERFAMILY SSF47384 224 303 2.75E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Gene3D G3DSA:3.30.565.10 315 468 6.6E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 SMART SM00388 241 306 7.3E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS16755 62d8999be0352246d34e08feecdf8a9b 468 Gene3D G3DSA:1.10.287.130 231 302 4.9E-9 T 28-03-2018 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 SMART SM00987 84 252 3.0E-30 T 28-03-2018 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 Gene3D G3DSA:3.40.470.10 25 264 3.5E-78 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 SUPERFAMILY SSF52141 39 262 1.0E-70 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 42 256 4.4E-69 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 Pfam PF03167 Uracil DNA glycosylase superfamily 89 252 2.0E-17 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 SMART SM00986 84 252 3.0E-30 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS01260 9f4a6a568ae052641361ec6992977ba3 267 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 41 263 35.01 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS05690 bf28782ec6fe283c43f0a5394de89776 566 Pfam PF00916 Sulfate permease family 20 384 1.7E-89 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFA_RS05690 bf28782ec6fe283c43f0a5394de89776 566 Pfam PF01740 STAS domain 439 539 6.9E-16 T 28-03-2018 IPR002645 STAS domain AFA_RS05690 bf28782ec6fe283c43f0a5394de89776 566 SUPERFAMILY SSF52091 435 543 6.67E-17 T 28-03-2018 IPR002645 STAS domain AFA_RS05690 bf28782ec6fe283c43f0a5394de89776 566 Gene3D G3DSA:3.30.750.24 419 553 1.8E-23 T 28-03-2018 IPR002645 STAS domain AFA_RS09915 9b6cd5e6ce43a1b84087944d040a0c1a 260 Gene3D G3DSA:3.50.50.60 11 252 5.3E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09915 9b6cd5e6ce43a1b84087944d040a0c1a 260 Pfam PF12059 Protein of unknown function (DUF3540) 73 260 1.9E-36 T 28-03-2018 IPR021927 Protein of unknown function DUF3540 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Gene3D G3DSA:3.40.50.300 248 423 5.2E-23 T 28-03-2018 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Gene3D G3DSA:1.10.8.60 425 495 3.3E-11 T 28-03-2018 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 553 573 8.5E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 536 553 8.5E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Pfam PF02954 Bacterial regulatory protein, Fis family 530 569 5.5E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Pfam PF01590 GAF domain 22 150 2.9E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Gene3D G3DSA:1.10.10.60 524 568 5.9E-16 T 28-03-2018 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 SUPERFAMILY SSF46689 505 570 1.95E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 SMART SM00382 271 415 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 SUPERFAMILY SSF52540 258 492 2.4E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Gene3D G3DSA:3.30.450.40 96 155 1.5E-5 T 28-03-2018 IPR029016 GAF domain-like AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 Pfam PF00158 Sigma-54 interaction domain 255 415 1.1E-57 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS04750 5ce32ce143f7be1c1f7003ea1368b97e 589 SUPERFAMILY SSF55781 12 152 3.92E-6 T 28-03-2018 IPR029016 GAF domain-like AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 103 3.1E-15 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 Gene3D G3DSA:1.20.5.810 19 51 1.6E-23 T 28-03-2018 AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 11 187 9.6E-67 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 Gene3D G3DSA:1.20.1290.10 52 187 1.2E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 68 116 3.7E-12 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS07245 133c3117cacac5321ca3f82a47744d6a 196 SUPERFAMILY SSF69118 10 195 4.11E-57 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS09075 b90a246a42d9493d16f1d9aa7bbd82f5 315 SUPERFAMILY SSF53187 3 310 2.23E-53 T 28-03-2018 AFA_RS09075 b90a246a42d9493d16f1d9aa7bbd82f5 315 Gene3D G3DSA:3.40.630.10 24 273 9.2E-19 T 28-03-2018 AFA_RS09075 b90a246a42d9493d16f1d9aa7bbd82f5 315 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 31 225 1.1E-14 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 Pfam PF03840 Preprotein translocase SecG subunit 8 76 2.8E-21 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 7 77 6.4E-24 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 PRINTS PR01651 Protein-export SecG membrane protein signature 58 80 2.9E-29 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 PRINTS PR01651 Protein-export SecG membrane protein signature 27 41 2.9E-29 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 PRINTS PR01651 Protein-export SecG membrane protein signature 42 58 2.9E-29 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS13435 11a29d44b0c84fa0197ba111065d515e 135 PRINTS PR01651 Protein-export SecG membrane protein signature 7 27 2.9E-29 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 Gene3D G3DSA:3.30.300.20 10 120 4.5E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 12 118 8.1E-21 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 100 2.0E-35 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 SUPERFAMILY SSF89919 9 116 8.11E-27 T 28-03-2018 IPR023799 Ribosome-binding factor A domain AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 8 120 17.268 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFA_RS05105 6dd608a39afd3ffab792cc8b2b73dbd7 137 Pfam PF02033 Ribosome-binding factor A 12 113 2.8E-24 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFA_RS03265 8f561cf3f1386d34ef006bf73c1e3223 216 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 8.5E-64 T 28-03-2018 AFA_RS03265 8f561cf3f1386d34ef006bf73c1e3223 216 SUPERFAMILY SSF53271 3 206 2.75E-65 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS03265 8f561cf3f1386d34ef006bf73c1e3223 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 2.4E-86 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFA_RS03265 8f561cf3f1386d34ef006bf73c1e3223 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 43.492 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFA_RS03265 8f561cf3f1386d34ef006bf73c1e3223 216 Gene3D G3DSA:3.40.50.2020 1 206 3.1E-60 T 28-03-2018 AFA_RS16895 e826aa957435385be11d343404645c79 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 156 4.1E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS16895 e826aa957435385be11d343404645c79 344 SUPERFAMILY SSF56042 163 338 5.36E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS16895 e826aa957435385be11d343404645c79 344 TIGRFAM TIGR00476 selD: selenide, water dikinase 6 312 1.9E-136 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFA_RS16895 e826aa957435385be11d343404645c79 344 Gene3D G3DSA:3.30.1330.10 1 161 1.3E-36 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS16895 e826aa957435385be11d343404645c79 344 Hamap MF_00625 Selenide, water dikinase [selD]. 4 344 44.794 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFA_RS16895 e826aa957435385be11d343404645c79 344 SUPERFAMILY SSF55326 6 160 6.67E-40 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS16895 e826aa957435385be11d343404645c79 344 Gene3D G3DSA:3.90.650.10 163 344 4.6E-45 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS16895 e826aa957435385be11d343404645c79 344 PIRSF PIRSF036407 1 344 1.3E-116 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AFA_RS16895 e826aa957435385be11d343404645c79 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 341 5.7E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS05430 78cab4188559744ff6f0ad8f80246acb 487 SUPERFAMILY SSF50249 39 124 5.14E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS05430 78cab4188559744ff6f0ad8f80246acb 487 SMART SM00316 37 118 2.6E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS05430 78cab4188559744ff6f0ad8f80246acb 487 Gene3D G3DSA:2.40.50.140 33 123 7.4E-28 T 28-03-2018 AFA_RS05430 78cab4188559744ff6f0ad8f80246acb 487 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 5.2E-149 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AFA_RS05430 78cab4188559744ff6f0ad8f80246acb 487 Pfam PF10150 Ribonuclease E/G family 120 391 5.7E-97 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 Gene3D G3DSA:1.20.970.10 2 73 2.3E-14 T 28-03-2018 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 Gene3D G3DSA:3.40.1030.10 75 344 7.3E-104 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 8 338 37.413 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 12 336 1.1E-125 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 Pfam PF00591 Glycosyl transferase family, a/b domain 79 328 3.0E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 69 1.0E-9 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 SUPERFAMILY SSF52418 79 341 1.83E-96 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFA_RS01350 635ddd2ae13e8a0e83f3b7220a20a2f1 344 SUPERFAMILY SSF47648 6 72 3.66E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 PIRSF PIRSF500136 1 420 1.3E-142 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 SUPERFAMILY SSF52413 317 419 3.27E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Gene3D G3DSA:3.40.50.720 229 420 1.5E-51 T 28-03-2018 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 PIRSF PIRSF000124 4 420 1.6E-72 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 SMART SM00984 324 420 2.5E-20 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Gene3D G3DSA:1.20.5.170 205 228 1.3E-15 T 28-03-2018 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 187 1.0E-55 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 SUPERFAMILY SSF51735 6 197 6.23E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Gene3D G3DSA:3.40.50.720 3 201 4.5E-43 T 28-03-2018 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 292 6.2E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 414 1.4E-114 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 418 9.1E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS17000 16ec6291bf74f321444da0cadf3ff6cf 420 SUPERFAMILY SSF48179 205 298 6.46E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS05495 10f7bf396a7787487ee3adb6ae17403a 361 Gene3D G3DSA:1.10.45.10 325 354 1.0E-5 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFA_RS05495 10f7bf396a7787487ee3adb6ae17403a 361 SUPERFAMILY SSF55103 193 353 2.62E-12 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS05495 10f7bf396a7787487ee3adb6ae17403a 361 Gene3D G3DSA:3.30.465.10 57 203 2.2E-29 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS05495 10f7bf396a7787487ee3adb6ae17403a 361 SUPERFAMILY SSF56176 13 178 1.26E-31 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS05495 10f7bf396a7787487ee3adb6ae17403a 361 Pfam PF01565 FAD binding domain 13 140 1.7E-19 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS09610 ad2078287055be0227f66739d124fbf5 169 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 14 142 3.2E-35 T 28-03-2018 IPR022262 Lipoprotein, putative AFA_RS05555 e90d742af549ec4bbbc80f5ab4cb774e 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS05555 e90d742af549ec4bbbc80f5ab4cb774e 483 Gene3D G3DSA:3.40.605.10 1 268 1.1E-82 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS05555 e90d742af549ec4bbbc80f5ab4cb774e 483 Pfam PF00171 Aldehyde dehydrogenase family 16 472 6.2E-146 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS05555 e90d742af549ec4bbbc80f5ab4cb774e 483 SUPERFAMILY SSF53720 3 479 5.89E-147 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS05555 e90d742af549ec4bbbc80f5ab4cb774e 483 Gene3D G3DSA:3.40.309.10 269 456 4.4E-62 T 28-03-2018 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SUPERFAMILY SSF52540 5 188 3.59E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Pfam PF09382 RQC domain 400 512 3.7E-36 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 604 1.0E-233 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SMART SM00341 532 608 1.2E-12 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SMART SM00490 243 324 2.0E-24 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SMART SM00487 14 210 3.8E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SMART SM00956 404 511 1.1E-47 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Gene3D G3DSA:3.40.50.300 202 396 1.1E-44 T 28-03-2018 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Pfam PF16124 RecQ zinc-binding 336 397 5.0E-17 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Pfam PF00570 HRDC domain 535 602 5.1E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Gene3D G3DSA:1.10.10.10 397 520 7.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SUPERFAMILY SSF52540 200 451 7.26E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Pfam PF00270 DEAD/DEAH box helicase 22 177 2.2E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 460 2.3E-153 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Pfam PF00271 Helicase conserved C-terminal domain 217 323 3.5E-16 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Gene3D G3DSA:1.10.150.80 521 608 1.9E-23 T 28-03-2018 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 Gene3D G3DSA:3.40.50.300 1 200 4.5E-33 T 28-03-2018 AFA_RS03595 20437247e353d69a6aea0b4653a1a6ae 608 SUPERFAMILY SSF47819 531 605 2.01E-20 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 Pfam PF13458 Periplasmic binding protein 17 356 1.3E-73 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 SUPERFAMILY SSF53822 17 361 3.74E-97 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 Gene3D G3DSA:3.40.50.2300 167 343 7.5E-28 T 28-03-2018 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 40 56 3.8E-13 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 18 34 3.8E-13 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 247 265 3.8E-13 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 59 77 3.8E-13 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS18525 8cb8fa3aa3423d2fcda92c736796c4f6 369 Gene3D G3DSA:3.40.50.2300 14 166 1.4E-35 T 28-03-2018 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 Gene3D G3DSA:3.20.20.105 1 376 1.7E-155 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 SUPERFAMILY SSF51713 4 371 1.96E-154 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 1.9E-157 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 8.9E-164 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 372 54.508 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS03250 f4388c89f11820f6f0988f11e4291bfa 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 369 2.1E-90 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 SUPERFAMILY SSF53383 1 400 2.69E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 Pfam PF00155 Aminotransferase class I and II 31 395 2.9E-80 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 Gene3D G3DSA:3.90.1150.10 3 76 1.2E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 Gene3D G3DSA:3.90.1150.10 304 399 3.8E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 Gene3D G3DSA:3.40.640.10 77 302 2.6E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 PRINTS PR00799 Aspartate aminotransferase signature 209 221 3.2E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 PRINTS PR00799 Aspartate aminotransferase signature 276 301 3.2E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 PRINTS PR00799 Aspartate aminotransferase signature 178 197 3.2E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS07695 a7af967ebfbc72d2023c3fc279a1e721 400 PRINTS PR00799 Aspartate aminotransferase signature 344 362 3.2E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 Pfam PF00696 Amino acid kinase family 7 216 3.4E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 PIRSF PIRSF005650 1 238 4.4E-91 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 SUPERFAMILY SSF53633 4 237 5.5E-72 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 44.193 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 Gene3D G3DSA:3.40.1160.10 2 238 3.5E-45 T 28-03-2018 AFA_RS10200 d22bb4d04423a39550e9889a00bdd4b7 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 6.6E-99 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFA_RS01480 680af723dd6fee12a11a225f4993b147 387 Pfam PF13458 Periplasmic binding protein 23 364 1.3E-66 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS01480 680af723dd6fee12a11a225f4993b147 387 Gene3D G3DSA:3.40.50.2300 20 175 2.6E-19 T 28-03-2018 AFA_RS01480 680af723dd6fee12a11a225f4993b147 387 Gene3D G3DSA:3.40.50.2300 176 331 4.7E-25 T 28-03-2018 AFA_RS01480 680af723dd6fee12a11a225f4993b147 387 SUPERFAMILY SSF53822 23 370 2.62E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS16200 ccbfae38edfc18e6ea00ac97b1f61cb3 289 SUPERFAMILY SSF47240 6 276 1.37E-42 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS16200 ccbfae38edfc18e6ea00ac97b1f61cb3 289 Gene3D G3DSA:1.10.620.20 1 187 1.2E-25 T 28-03-2018 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Pfam PF00676 Dehydrogenase E1 component 221 525 8.5E-48 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 803 945 1.6E-51 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 SMART SM00861 601 798 6.8E-58 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 SUPERFAMILY SSF52518 584 805 5.67E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Gene3D G3DSA:3.40.50.970 600 814 7.1E-58 T 28-03-2018 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 SUPERFAMILY SSF52518 126 548 1.1E-89 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Gene3D G3DSA:1.10.287.1150 89 172 1.1E-21 T 28-03-2018 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 944 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Pfam PF02779 Transketolase, pyrimidine binding domain 600 798 1.1E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Gene3D G3DSA:3.40.50.970 173 532 2.4E-87 T 28-03-2018 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 11 49 1.9E-16 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFA_RS04890 58bd1cfe06d5e9d2d69b0d404b6a25bd 955 PIRSF PIRSF000157 1 947 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AFA_RS09615 bcc04d2271bcc65546d9237a58dc9611 976 SUPERFAMILY SSF52540 671 900 3.17E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09615 bcc04d2271bcc65546d9237a58dc9611 976 SUPERFAMILY SSF52540 481 596 3.17E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09615 bcc04d2271bcc65546d9237a58dc9611 976 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 52 330 4.5E-57 T 28-03-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase AFA_RS09615 bcc04d2271bcc65546d9237a58dc9611 976 Gene3D G3DSA:3.40.50.300 520 920 9.7E-19 T 28-03-2018 AFA_RS09615 bcc04d2271bcc65546d9237a58dc9611 976 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 41 975 0.0 T 28-03-2018 IPR022303 Conjugative transfer ATPase AFA_RS14755 189a21fbec36624a0a0cb6fa8f0b6e09 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS14755 189a21fbec36624a0a0cb6fa8f0b6e09 509 Gene3D G3DSA:3.40.309.10 281 477 1.4E-51 T 28-03-2018 AFA_RS14755 189a21fbec36624a0a0cb6fa8f0b6e09 509 Pfam PF00171 Aldehyde dehydrogenase family 32 488 2.2E-126 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS14755 189a21fbec36624a0a0cb6fa8f0b6e09 509 SUPERFAMILY SSF53720 32 496 2.36E-130 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS14755 189a21fbec36624a0a0cb6fa8f0b6e09 509 Gene3D G3DSA:3.40.605.10 26 280 6.3E-72 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 Pfam PF03061 Thioesterase superfamily 24 109 1.5E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 SUPERFAMILY SSF54637 10 138 5.14E-40 T 28-03-2018 IPR029069 HotDog domain AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 14 126 1.4E-33 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 11 133 6.0E-51 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 Gene3D G3DSA:3.10.129.10 3 141 5.8E-37 T 28-03-2018 AFA_RS14610 3369e601ef2e4d364e14263594aaf428 141 PIRSF PIRSF003230 3 141 3.1E-48 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFA_RS14655 1fba1e59dd350628fada0ee2d515db54 145 Pfam PF03061 Thioesterase superfamily 57 116 7.3E-10 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS14655 1fba1e59dd350628fada0ee2d515db54 145 SUPERFAMILY SSF54637 11 141 7.68E-22 T 28-03-2018 IPR029069 HotDog domain AFA_RS14655 1fba1e59dd350628fada0ee2d515db54 145 Gene3D G3DSA:3.10.129.10 11 145 1.3E-22 T 28-03-2018 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 Gene3D G3DSA:3.40.630.30 306 451 7.7E-22 T 28-03-2018 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 Gene3D G3DSA:3.40.1160.10 20 304 3.5E-53 T 28-03-2018 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 451 185.714 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 22 451 3.4E-169 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 Pfam PF13508 Acetyltransferase (GNAT) domain 344 423 9.3E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 SUPERFAMILY SSF55729 307 431 2.16E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 SUPERFAMILY SSF53633 19 302 3.35E-56 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 Pfam PF00696 Amino acid kinase family 39 222 2.8E-19 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase AFA_RS05355 8521d2737c8c2c137fae740ccb53382a 451 PIRSF PIRSF000423 12 451 8.9E-173 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 SUPERFAMILY SSF51366 7 222 9.42E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 PIRSF PIRSF001461 3 231 2.4E-101 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 Gene3D G3DSA:3.20.20.70 1 226 1.3E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 138 160 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 9 222 3.1E-94 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS01375 88a1343190dde41e54c2bc7fe61d41a8 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 9 209 2.2E-87 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 2.8E-6 T 28-03-2018 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 31 53 2.8E-6 T 28-03-2018 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 65 80 2.8E-6 T 28-03-2018 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 SUPERFAMILY SSF51905 30 254 7.12E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 SUPERFAMILY SSF51905 346 399 7.12E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 Gene3D G3DSA:3.50.50.60 18 403 1.5E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14760 7c19a1823db31ad270fd188c71887c8a 434 Pfam PF01266 FAD dependent oxidoreductase 31 383 4.3E-48 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 7.7E-132 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 SUPERFAMILY SSF103263 4 351 3.53E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 Pfam PF01264 Chorismate synthase 10 345 5.0E-130 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 35.27 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 Gene3D G3DSA:3.60.150.10 3 353 2.8E-146 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 PIRSF PIRSF001456 3 352 7.2E-130 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS10835 ea873a403ebe857b5f8aff8d2f7e9487 353 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFA_RS16185 8dc48e75c1fe8e3a97b81d401109a4e3 226 Gene3D G3DSA:3.40.50.150 4 224 3.5E-29 T 28-03-2018 AFA_RS16185 8dc48e75c1fe8e3a97b81d401109a4e3 226 SUPERFAMILY SSF53335 8 217 7.43E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16185 8dc48e75c1fe8e3a97b81d401109a4e3 226 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 205 1.8E-36 T 28-03-2018 AFA_RS11795 283595e0b72453250647478bfa521670 190 PIRSF PIRSF000847 1 190 3.9E-47 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFA_RS11795 283595e0b72453250647478bfa521670 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 187 6.4E-55 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFA_RS11795 283595e0b72453250647478bfa521670 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 2.5E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFA_RS11795 283595e0b72453250647478bfa521670 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.4E-31 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Pfam PF14450 Cell division protein FtsA 206 373 4.3E-25 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Pfam PF14450 Cell division protein FtsA 10 192 3.1E-10 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 SUPERFAMILY SSF53067 7 196 2.33E-62 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 PIRSF PIRSF003101 1 408 3.6E-153 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Gene3D G3DSA:3.30.420.40 3 185 6.3E-40 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 SMART SM00842 9 195 1.3E-105 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 SUPERFAMILY SSF53067 198 375 5.94E-48 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 376 1.9E-149 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 406 30.348 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Gene3D G3DSA:3.90.640.10 250 299 1.8E-19 T 28-03-2018 AFA_RS03685 d99e2454786d368525adbfc1d2aef406 408 Gene3D G3DSA:3.30.420.40 196 249 2.5E-8 T 28-03-2018 AFA_RS05125 4d715e3a82d4bac1211774a79b26bc64 129 Pfam PF07849 Protein of unknown function (DUF1641) 86 117 2.3E-8 T 28-03-2018 IPR012440 Protein of unknown function DUF1641 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 SUPERFAMILY SSF56935 39 734 3.26E-130 T 28-03-2018 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 Gene3D G3DSA:2.170.130.10 36 186 5.5E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 Gene3D G3DSA:2.40.170.20 188 734 8.3E-83 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 78 734 1.5E-98 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 174 5.5E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS02395 f3f90e858d0c4f4c7e4bb14e0df0fa81 735 Pfam PF00593 TonB dependent receptor 257 733 1.4E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Gene3D G3DSA:3.10.20.310 184 275 5.5E-18 T 28-03-2018 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF01103 Surface antigen 457 780 1.8E-65 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF07244 Surface antigen variable number repeat 185 272 2.0E-14 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF07244 Surface antigen variable number repeat 356 430 1.1E-12 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF07244 Surface antigen variable number repeat 277 353 5.4E-9 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF07244 Surface antigen variable number repeat 34 100 4.5E-6 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Pfam PF07244 Surface antigen variable number repeat 101 181 5.3E-8 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 12 780 24.776 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Gene3D G3DSA:3.10.20.310 31 100 6.7E-13 T 28-03-2018 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Gene3D G3DSA:2.40.160.50 390 780 3.7E-78 T 28-03-2018 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Gene3D G3DSA:3.10.20.310 276 355 2.5E-12 T 28-03-2018 AFA_RS10170 2bce958493249964995b71887ea53c15 780 PIRSF PIRSF006076 2 780 3.9E-235 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFA_RS10170 2bce958493249964995b71887ea53c15 780 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 33 780 7.1E-249 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFA_RS10170 2bce958493249964995b71887ea53c15 780 Gene3D G3DSA:3.10.20.310 101 183 6.7E-11 T 28-03-2018 AFA_RS07995 5bc86147c8db9ac6954ed27f50ad5d59 121 PIRSF PIRSF039020 1 121 4.2E-45 T 28-03-2018 IPR026275 Glyoxalase/dioxygenase/EhpR AFA_RS07995 5bc86147c8db9ac6954ed27f50ad5d59 121 Gene3D G3DSA:3.10.180.10 1 121 7.1E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS07995 5bc86147c8db9ac6954ed27f50ad5d59 121 SUPERFAMILY SSF54593 6 120 6.62E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS07995 5bc86147c8db9ac6954ed27f50ad5d59 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 115 1.7E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS11615 4d8c21a2af34080a313eeda8d4f2e55f 84 Pfam PF01206 Sulfurtransferase TusA 15 76 6.7E-22 T 28-03-2018 IPR001455 TusA-like domain AFA_RS11615 4d8c21a2af34080a313eeda8d4f2e55f 84 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 16 40 - T 28-03-2018 IPR001455 TusA-like domain AFA_RS11615 4d8c21a2af34080a313eeda8d4f2e55f 84 SUPERFAMILY SSF64307 11 81 6.67E-22 T 28-03-2018 IPR001455 TusA-like domain AFA_RS11615 4d8c21a2af34080a313eeda8d4f2e55f 84 Gene3D G3DSA:3.30.110.40 2 84 1.2E-25 T 28-03-2018 IPR001455 TusA-like domain AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 458 602 7.6E-20 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 SUPERFAMILY SSF52518 20 248 7.36E-27 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 Gene3D G3DSA:3.30.70.20 646 696 4.0E-4 T 28-03-2018 AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 SUPERFAMILY SSF52518 424 651 3.3E-29 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 Gene3D G3DSA:3.40.50.970 24 261 1.2E-15 T 28-03-2018 AFA_RS00250 836ad01a2d26d10721fe674f08334722 736 Gene3D G3DSA:3.40.50.970 468 645 5.9E-21 T 28-03-2018 AFA_RS04370 fcd34d323ee5bbf1b620acf6677bce5d 388 Pfam PF00155 Aminotransferase class I and II 42 380 2.6E-47 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS04370 fcd34d323ee5bbf1b620acf6677bce5d 388 Gene3D G3DSA:3.90.1150.10 282 388 5.8E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS04370 fcd34d323ee5bbf1b620acf6677bce5d 388 Gene3D G3DSA:3.40.640.10 48 281 6.7E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS04370 fcd34d323ee5bbf1b620acf6677bce5d 388 SUPERFAMILY SSF53383 4 385 1.71E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS12475 fe24afd482a37e465b732e6a8ed8048d 523 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 220 1.7E-24 T 28-03-2018 AFA_RS13145 cfcc86ce684b89db429417a4fb0b713a 240 Gene3D G3DSA:3.30.950.10 124 237 4.7E-25 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS13145 cfcc86ce684b89db429417a4fb0b713a 240 PIRSF PIRSF005917 7 238 3.0E-44 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS13145 cfcc86ce684b89db429417a4fb0b713a 240 SUPERFAMILY SSF53790 7 236 3.01E-58 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS13145 cfcc86ce684b89db429417a4fb0b713a 240 Gene3D G3DSA:3.40.1010.10 4 123 2.4E-24 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Gene3D G3DSA:3.40.50.740 168 401 6.0E-19 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 SUPERFAMILY SSF50692 890 1038 5.42E-23 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 SUPERFAMILY SSF53706 83 120 7.25E-99 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 SUPERFAMILY SSF53706 147 894 7.25E-99 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Gene3D G3DSA:2.20.25.90 76 167 7.9E-12 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Gene3D G3DSA:2.40.40.20 864 1041 2.0E-26 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 SMART SM00926 81 163 5.4E-12 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Gene3D G3DSA:3.40.50.740 476 803 2.6E-23 T 28-03-2018 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Pfam PF00384 Molybdopterin oxidoreductase 246 699 1.8E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS09180 e2522ebd73d20a3689f0c0e9314e914f 1041 Pfam PF01568 Molydopterin dinucleotide binding domain 908 997 5.8E-12 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 AFA_RS07930 938d9e8c0b57bb93394b1a2dd1a3cf9e 497 Pfam PF04986 Putative transposase 171 393 9.0E-58 T 28-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 AFA_RS07930 938d9e8c0b57bb93394b1a2dd1a3cf9e 497 Pfam PF14319 Transposase zinc-binding domain 39 142 9.6E-26 T 28-03-2018 IPR026889 Transposase zinc-binding domain AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 SUPERFAMILY SSF52540 10 258 1.96E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 SMART SM00382 36 235 9.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 Pfam PF00005 ABC transporter 27 187 6.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 5.3E-12 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS07455 096d7a2e859610c79acd6d7c76505d45 274 Gene3D G3DSA:3.40.50.300 8 274 7.3E-60 T 28-03-2018 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 SUPERFAMILY SSF53383 149 607 2.6E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Gene3D G3DSA:3.90.100.10 638 755 3.0E-32 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 614 739 2.1E-42 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 PIRSF PIRSF009393 1 755 4.6E-266 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Gene3D G3DSA:3.90.1150.10 459 637 1.7E-68 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 149 587 1.3E-143 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 143 4.9E-36 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 SUPERFAMILY SSF55904 609 754 4.32E-41 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFA_RS10455 3281adff4b2a5aac240b46b3e5af4a27 755 Gene3D G3DSA:3.40.640.10 149 458 3.8E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 Pfam PF03466 LysR substrate binding domain 89 286 1.2E-35 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 SUPERFAMILY SSF53850 89 289 2.53E-38 T 28-03-2018 AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 SUPERFAMILY SSF46785 1 111 9.43E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 Gene3D G3DSA:1.10.10.10 1 84 5.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 Gene3D G3DSA:3.40.190.10 89 173 6.4E-12 T 28-03-2018 AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12980 655da88288a21f096f510992cd8ee53c 297 Gene3D G3DSA:3.40.190.10 174 256 5.5E-12 T 28-03-2018 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 SUPERFAMILY SSF52440 7 99 4.22E-31 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 PIRSF PIRSF039102 5 56 4.4E-9 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 PIRSF PIRSF039102 47 312 2.0E-84 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 306 35.298 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Gene3D G3DSA:3.30.470.20 169 314 1.2E-40 T 28-03-2018 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 305 1.9E-98 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Pfam PF07478 D-ala D-ala ligase C-terminus 107 302 8.1E-56 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Gene3D G3DSA:3.40.50.20 1 99 2.0E-35 T 28-03-2018 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 SUPERFAMILY SSF56059 99 307 2.36E-58 T 28-03-2018 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Pfam PF01820 D-ala D-ala ligase N-terminus 7 89 6.8E-20 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS03675 867c0fb1d25b4692dc1f682172344153 316 Gene3D G3DSA:3.30.1490.20 100 168 3.5E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 298 314 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 Gene3D G3DSA:1.20.1250.20 226 432 7.1E-27 T 28-03-2018 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 Gene3D G3DSA:1.20.1250.20 13 225 2.9E-22 T 28-03-2018 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 Pfam PF00083 Sugar (and other) transporter 22 220 3.0E-24 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 Pfam PF00083 Sugar (and other) transporter 231 430 2.0E-18 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS06590 735a105c80284996c005f04476c3b5af 432 SUPERFAMILY SSF103473 15 429 1.7E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS06590 735a105c80284996c005f04476c3b5af 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Pfam PF13549 ATP-grasp domain 488 706 4.7E-59 T 28-03-2018 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Gene3D G3DSA:3.30.1490.20 514 577 1.5E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 172 306 2.0E-34 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Pfam PF13380 CoA binding domain 22 145 1.2E-20 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 SMART SM00881 17 112 6.1E-29 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 SUPERFAMILY SSF51735 13 151 1.01E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 SUPERFAMILY SSF56059 496 709 2.05E-38 T 28-03-2018 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 SUPERFAMILY SSF52210 317 471 5.1E-25 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Gene3D G3DSA:3.40.50.261 311 481 4.2E-23 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Gene3D G3DSA:3.30.470.20 578 712 1.4E-23 T 28-03-2018 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Gene3D G3DSA:3.40.50.720 17 143 2.0E-34 T 28-03-2018 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 SUPERFAMILY SSF52210 147 308 4.06E-27 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15945 f6e7e55f84177735b99ec1d6262b2d10 713 Gene3D G3DSA:3.40.50.261 144 310 5.5E-31 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS07235 8b92e5c4a2a90d5da3603a1e9344d796 137 Gene3D G3DSA:3.90.79.10 2 136 4.8E-22 T 28-03-2018 AFA_RS07235 8b92e5c4a2a90d5da3603a1e9344d796 137 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS07235 8b92e5c4a2a90d5da3603a1e9344d796 137 Pfam PF00293 NUDIX domain 9 119 6.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS07235 8b92e5c4a2a90d5da3603a1e9344d796 137 SUPERFAMILY SSF55811 4 124 7.99E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Gene3D G3DSA:1.10.540.10 1 120 1.9E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 8.2E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Gene3D G3DSA:2.40.110.10 122 221 7.6E-28 T 28-03-2018 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 SUPERFAMILY SSF47203 231 386 2.09E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 361 9.4E-35 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Gene3D G3DSA:1.20.140.10 222 388 1.5E-46 T 28-03-2018 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 1.6E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 SUPERFAMILY SSF56645 2 246 5.37E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 PIRSF PIRSF016578 2 96 0.0067 T 28-03-2018 AFA_RS02125 7d835bc207d8c0a79e3c2285b46fd37c 388 PIRSF PIRSF016578 243 385 3.2E-9 T 28-03-2018 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 Gene3D G3DSA:2.40.50.140 2 69 8.5E-25 T 28-03-2018 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 67 5.0E-26 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 PIRSF PIRSF002599 1 69 1.2E-20 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 SUPERFAMILY SSF50249 4 68 2.94E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 PRINTS PR00050 Cold shock protein signature 27 36 2.9E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 PRINTS PR00050 Cold shock protein signature 42 60 2.9E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 PRINTS PR00050 Cold shock protein signature 6 21 2.9E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 SMART SM00357 5 69 1.6E-23 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS08855 d93301ccf82639c695150ef9ee2f11ca 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS00390 e321d680f2555cd5f910ef8f9ad68229 205 SUPERFAMILY SSF50475 4 188 1.42E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS00390 e321d680f2555cd5f910ef8f9ad68229 205 Pfam PF01613 Flavin reductase like domain 30 164 1.7E-13 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS00390 e321d680f2555cd5f910ef8f9ad68229 205 Gene3D G3DSA:2.30.110.10 8 199 2.3E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS00390 e321d680f2555cd5f910ef8f9ad68229 205 SMART SM00903 25 174 2.7E-7 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 3.1E-5 T 28-03-2018 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.1E-5 T 28-03-2018 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 3.1E-5 T 28-03-2018 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 SUPERFAMILY SSF51905 2 159 1.76E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 SUPERFAMILY SSF51905 281 362 1.76E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00370 357db25d97b62771d8cc80aa64bef7db 414 Gene3D G3DSA:3.50.50.60 3 361 7.8E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS17930 f5a0c3bacc3401aa45ee9d9fc9da4d62 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 197 5.9E-60 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFA_RS17930 f5a0c3bacc3401aa45ee9d9fc9da4d62 207 Pfam PF01926 50S ribosome-binding GTPase 26 151 1.1E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS17930 f5a0c3bacc3401aa45ee9d9fc9da4d62 207 Gene3D G3DSA:3.40.50.300 3 205 1.7E-28 T 28-03-2018 AFA_RS17930 f5a0c3bacc3401aa45ee9d9fc9da4d62 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 201 25.764 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFA_RS17930 f5a0c3bacc3401aa45ee9d9fc9da4d62 207 SUPERFAMILY SSF52540 8 201 3.81E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 SUPERFAMILY SSF46689 383 433 2.24E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Gene3D G3DSA:1.10.8.60 313 395 4.4E-21 T 28-03-2018 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 SMART SM00448 1 112 4.2E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Pfam PF00158 Sigma-54 interaction domain 141 307 6.6E-64 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Gene3D G3DSA:3.40.50.300 139 312 2.9E-22 T 28-03-2018 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 SUPERFAMILY SSF52172 3 186 1.99E-42 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Gene3D G3DSA:3.40.50.2300 1 138 5.4E-35 T 28-03-2018 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 SUPERFAMILY SSF52540 142 370 1.38E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Gene3D G3DSA:1.10.10.60 396 433 1.9E-11 T 28-03-2018 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Pfam PF00072 Response regulator receiver domain 3 112 4.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 SMART SM00382 161 304 3.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15220 5cd635ffdf4e02f012f63004faa1941b 446 Pfam PF02954 Bacterial regulatory protein, Fis family 391 431 7.6E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS11825 5689acfaaf14b132bb1136a98282fcca 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 5.9E-62 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS11825 5689acfaaf14b132bb1136a98282fcca 263 Gene3D G3DSA:1.10.12.10 222 263 1.2E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS11825 5689acfaaf14b132bb1136a98282fcca 263 Gene3D G3DSA:3.90.226.10 5 221 3.8E-63 T 28-03-2018 AFA_RS11825 5689acfaaf14b132bb1136a98282fcca 263 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 7 263 2.2E-127 T 28-03-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 AFA_RS11825 5689acfaaf14b132bb1136a98282fcca 263 SUPERFAMILY SSF52096 4 262 5.46E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 Pfam PF13932 GidA associated domain 405 625 5.4E-75 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 Gene3D G3DSA:3.50.50.60 5 265 2.2E-76 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 SUPERFAMILY SSF51905 6 66 2.22E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 SUPERFAMILY SSF51905 97 262 2.22E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 SMART SM01228 555 626 9.4E-39 T 28-03-2018 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 Pfam PF01134 Glucose inhibited division protein A 8 402 3.2E-169 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 631 6.7E-277 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFA_RS18420 dbe319bd020a0a5031d87ed6e0c0cfca 638 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 633 43.132 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFA_RS15160 df2157a1a9f176a69cceee0e33654819 655 Gene3D G3DSA:2.170.130.10 15 144 1.2E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS15160 df2157a1a9f176a69cceee0e33654819 655 Gene3D G3DSA:2.40.170.20 145 655 7.6E-56 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS15160 df2157a1a9f176a69cceee0e33654819 655 SUPERFAMILY SSF56935 32 655 2.02E-93 T 28-03-2018 AFA_RS15160 df2157a1a9f176a69cceee0e33654819 655 Pfam PF00593 TonB dependent receptor 237 654 8.3E-39 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS15160 df2157a1a9f176a69cceee0e33654819 655 Pfam PF07715 TonB-dependent Receptor Plug Domain 34 137 4.8E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 SUPERFAMILY SSF51735 7 146 2.53E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 SUPERFAMILY SSF52210 311 464 1.57E-20 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 SUPERFAMILY SSF56059 487 699 5.21E-36 T 28-03-2018 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Gene3D G3DSA:3.40.50.720 9 133 4.9E-33 T 28-03-2018 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Gene3D G3DSA:3.40.50.261 309 472 5.8E-23 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Pfam PF13380 CoA binding domain 18 142 8.9E-20 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 SMART SM00881 13 108 1.7E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 165 298 4.2E-43 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Pfam PF13549 ATP-grasp domain 483 698 9.7E-68 T 28-03-2018 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Gene3D G3DSA:3.30.1490.20 506 568 9.1E-27 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Gene3D G3DSA:3.40.50.261 134 308 1.1E-32 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 Gene3D G3DSA:3.30.470.20 569 700 4.5E-22 T 28-03-2018 AFA_RS15275 92a36bf00d309801dc72720d7a9a8606 700 SUPERFAMILY SSF52210 139 303 5.1E-34 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS02905 459432dde725c7bd43e4830b1658e55f 149 Pfam PF03100 CcmE 4 131 2.8E-47 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AFA_RS02905 459432dde725c7bd43e4830b1658e55f 149 SUPERFAMILY SSF82093 29 136 8.63E-37 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AFA_RS02905 459432dde725c7bd43e4830b1658e55f 149 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 141 33.036 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AFA_RS02905 459432dde725c7bd43e4830b1658e55f 149 Gene3D G3DSA:2.40.50.140 26 125 4.1E-33 T 28-03-2018 AFA_RS13560 25a88ea2b0c9209f0602ef9a86f7e961 108 Pfam PF14559 Tetratricopeptide repeat 27 77 1.5E-10 T 28-03-2018 AFA_RS13560 25a88ea2b0c9209f0602ef9a86f7e961 108 SUPERFAMILY SSF48452 5 85 1.1E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13560 25a88ea2b0c9209f0602ef9a86f7e961 108 SMART SM00028 50 83 1.3 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS13560 25a88ea2b0c9209f0602ef9a86f7e961 108 SMART SM00028 16 49 0.0012 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS13560 25a88ea2b0c9209f0602ef9a86f7e961 108 Gene3D G3DSA:1.25.40.10 1 108 9.8E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 Gene3D G3DSA:1.10.10.10 4 91 7.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 Gene3D G3DSA:3.40.190.10 196 271 1.1E-5 T 28-03-2018 AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 Gene3D G3DSA:3.40.190.10 92 195 1.6E-8 T 28-03-2018 AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 SUPERFAMILY SSF46785 6 88 5.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 Pfam PF03466 LysR substrate binding domain 90 294 3.1E-22 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 SUPERFAMILY SSF53850 92 295 1.81E-23 T 28-03-2018 AFA_RS00025 b29943fe52ff261027cbd6c4abb21194 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 8.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 SUPERFAMILY SSF48300 3 61 1.57E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 2.5E-47 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 Gene3D G3DSA:3.30.1390.10 55 125 1.0E-30 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 6.0E-31 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 125 25.589 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 Gene3D G3DSA:1.20.5.710 2 54 1.8E-15 T 28-03-2018 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 3 51 1.0E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 1.0E-20 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18350 f854f9c63b24210ad65727faf89a601e 125 SUPERFAMILY SSF54736 54 125 4.36E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFA_RS09345 d93437b5da5cc42686b3bcf47df27aa4 128 SUPERFAMILY SSF55298 1 126 1.41E-40 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS09345 d93437b5da5cc42686b3bcf47df27aa4 128 Gene3D G3DSA:3.30.1330.40 1 127 1.1E-41 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS09345 d93437b5da5cc42686b3bcf47df27aa4 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 3.3E-43 T 28-03-2018 IPR006056 RidA family AFA_RS09345 d93437b5da5cc42686b3bcf47df27aa4 128 Pfam PF01042 Endoribonuclease L-PSP 9 126 2.7E-39 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family AFA_RS04670 13caa731bedf43a9a364c2a71e372bc5 389 Gene3D G3DSA:3.20.20.70 5 380 2.5E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS04670 13caa731bedf43a9a364c2a71e372bc5 389 Pfam PF01070 FMN-dependent dehydrogenase 16 378 2.9E-131 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 AFA_RS04670 13caa731bedf43a9a364c2a71e372bc5 389 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 276 282 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 AFA_RS04670 13caa731bedf43a9a364c2a71e372bc5 389 PIRSF PIRSF000138 1 382 4.7E-122 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 AFA_RS04670 13caa731bedf43a9a364c2a71e372bc5 389 SUPERFAMILY SSF51395 5 378 9.16E-105 T 28-03-2018 AFA_RS01980 f62151db64108d6159a14b35b1802c6b 240 Gene3D G3DSA:3.40.50.300 1 236 1.3E-49 T 28-03-2018 AFA_RS01980 f62151db64108d6159a14b35b1802c6b 240 SMART SM00382 32 214 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01980 f62151db64108d6159a14b35b1802c6b 240 Pfam PF00005 ABC transporter 23 165 5.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01980 f62151db64108d6159a14b35b1802c6b 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01980 f62151db64108d6159a14b35b1802c6b 240 SUPERFAMILY SSF52540 4 229 3.12E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 6.9E-11 T 28-03-2018 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 6.9E-11 T 28-03-2018 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 6.9E-11 T 28-03-2018 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 SUPERFAMILY SSF51905 5 177 6.48E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 SUPERFAMILY SSF51905 269 381 6.48E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 287 300 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 381 3.1E-84 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 Gene3D G3DSA:3.50.50.60 3 356 1.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS14420 e2148a39928a5539bdb8b6aae90202e6 386 Pfam PF01494 FAD binding domain 160 312 6.2E-8 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 Gene3D G3DSA:3.40.50.720 45 260 3.3E-57 T 28-03-2018 AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 Gene3D G3DSA:3.40.50.720 1 44 2.2E-8 T 28-03-2018 AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 2.2E-104 T 28-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 Pfam PF00106 short chain dehydrogenase 5 197 1.9E-56 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 SUPERFAMILY SSF51735 3 259 1.0E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13505 b99fe528c0cd5b5394a138d1dbc57f0f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 SUPERFAMILY SSF52540 51 287 7.27E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 ProSitePatterns PS00211 ABC transporters family signature. 189 203 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 SMART SM00382 78 266 5.7E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 Gene3D G3DSA:3.30.70.260 301 392 2.3E-17 T 28-03-2018 AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 SUPERFAMILY SSF55021 296 369 1.49E-8 T 28-03-2018 AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 Pfam PF00005 ABC transporter 69 217 2.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 Pfam PF09383 NIL domain 317 367 1.2E-9 T 28-03-2018 IPR018449 NIL domain AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 Gene3D G3DSA:3.40.50.300 45 300 1.7E-79 T 28-03-2018 AFA_RS00485 9c54503f1c184ebc809cc9cf8c6b12f4 401 SMART SM00930 314 391 0.0078 T 28-03-2018 IPR018449 NIL domain AFA_RS00700 3137f66cac72cef9285c2d1df29103f9 358 SMART SM00849 42 271 2.5E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00700 3137f66cac72cef9285c2d1df29103f9 358 SUPERFAMILY SSF56281 15 355 1.17E-68 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00700 3137f66cac72cef9285c2d1df29103f9 358 Pfam PF00753 Metallo-beta-lactamase superfamily 42 271 1.3E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00700 3137f66cac72cef9285c2d1df29103f9 358 Gene3D G3DSA:3.60.15.10 17 293 8.0E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS12935 d5c2ef5d69390af5d0dba08f42b2433b 140 Pfam PF13279 Thioesterase-like superfamily 17 122 1.4E-13 T 28-03-2018 AFA_RS12935 d5c2ef5d69390af5d0dba08f42b2433b 140 SUPERFAMILY SSF54637 11 136 3.36E-29 T 28-03-2018 IPR029069 HotDog domain AFA_RS12935 d5c2ef5d69390af5d0dba08f42b2433b 140 Gene3D G3DSA:3.10.129.10 6 140 1.8E-30 T 28-03-2018 AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 Pfam PF08402 TOBE domain 274 343 1.2E-11 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 SUPERFAMILY SSF52540 4 240 2.18E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 SUPERFAMILY SSF50331 243 343 2.96E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 Pfam PF00005 ABC transporter 20 161 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 SMART SM00382 28 211 2.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 Gene3D G3DSA:3.40.50.300 1 243 6.6E-74 T 28-03-2018 AFA_RS04630 e3d66f5830570c4f9c321c9cc86bfa2e 349 Gene3D G3DSA:2.40.50.140 277 340 1.2E-8 T 28-03-2018 AFA_RS10165 43b78901cae10c8db6e50ead3f0f801b 184 SMART SM00935 31 183 1.6E-53 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 AFA_RS10165 43b78901cae10c8db6e50ead3f0f801b 184 PIRSF PIRSF002094 19 184 1.1E-49 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 AFA_RS10165 43b78901cae10c8db6e50ead3f0f801b 184 SUPERFAMILY SSF111384 42 182 8.24E-34 T 28-03-2018 IPR024930 Skp domain AFA_RS10165 43b78901cae10c8db6e50ead3f0f801b 184 Pfam PF03938 Outer membrane protein (OmpH-like) 28 182 1.2E-34 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 AFA_RS10165 43b78901cae10c8db6e50ead3f0f801b 184 Gene3D G3DSA:3.30.910.20 31 183 1.0E-23 T 28-03-2018 AFA_RS01120 054576cc5f464bf7ef14debdf8024f88 338 SUPERFAMILY SSF53850 24 255 6.29E-43 T 28-03-2018 AFA_RS01120 054576cc5f464bf7ef14debdf8024f88 338 SMART SM00062 33 263 2.8E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01120 054576cc5f464bf7ef14debdf8024f88 338 Gene3D G3DSA:3.40.190.10 23 137 4.2E-18 T 28-03-2018 AFA_RS01120 054576cc5f464bf7ef14debdf8024f88 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 247 1.1E-28 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01120 054576cc5f464bf7ef14debdf8024f88 338 Gene3D G3DSA:3.40.190.10 138 226 8.0E-14 T 28-03-2018 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 Pfam PF07690 Major Facilitator Superfamily 12 345 1.0E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 Gene3D G3DSA:1.20.1250.20 2 197 2.3E-26 T 28-03-2018 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 Gene3D G3DSA:1.20.1250.20 198 405 1.4E-28 T 28-03-2018 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 270 287 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 ProSitePatterns PS00217 Sugar transport proteins signature 2. 101 126 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS16770 e32dafcfd04197421cf9c06da6717388 406 SUPERFAMILY SSF103473 1 403 1.83E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS14675 e3c3529d99b1b31abfe19cdf7c21c2ca 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 337 4.2E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS14675 e3c3529d99b1b31abfe19cdf7c21c2ca 353 Gene3D G3DSA:1.10.3470.10 8 343 2.0E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Gene3D G3DSA:2.40.50.140 1 114 2.6E-46 T 28-03-2018 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 SMART SM01383 42 118 8.6E-45 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Gene3D G3DSA:4.10.950.10 197 273 5.3E-35 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 PIRSF PIRSF002158 7 275 7.1E-102 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Gene3D G3DSA:2.30.30.30 119 195 4.5E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 2.4E-128 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 SMART SM01382 124 252 3.4E-86 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 SUPERFAMILY SSF50249 3 124 5.14E-49 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 4.7E-55 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 3.7E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.394 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFA_RS18255 1c456ec5133bdeed804a8dcaa146708a 275 SUPERFAMILY SSF50104 127 272 3.73E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 Gene3D G3DSA:3.20.20.450 406 639 3.8E-19 T 28-03-2018 IPR001633 EAL domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 SUPERFAMILY SSF55073 247 398 1.26E-14 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 SMART SM00052 414 641 0.0037 T 28-03-2018 IPR001633 EAL domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 SUPERFAMILY SSF141868 420 620 2.35E-15 T 28-03-2018 IPR001633 EAL domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 Gene3D G3DSA:3.30.70.270 225 400 8.2E-20 T 28-03-2018 AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 SMART SM00267 230 400 5.1E-7 T 28-03-2018 IPR000160 GGDEF domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 Pfam PF16448 LapD/MoxY periplasmic domain 24 148 5.1E-36 T 28-03-2018 IPR032244 LapD/MoxY, periplasmic domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 Pfam PF00563 EAL domain 421 620 1.5E-12 T 28-03-2018 IPR001633 EAL domain AFA_RS18055 4034e16b461de831424be16ad7dc2eba 646 Pfam PF00990 Diguanylate cyclase, GGDEF domain 242 394 6.3E-12 T 28-03-2018 IPR000160 GGDEF domain AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 38 46 4.5E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 4.5E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 64 75 4.5E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 Gene3D G3DSA:3.40.50.1820 1 314 9.7E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 PIRSF PIRSF006431 1 315 9.5E-137 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 SUPERFAMILY SSF53474 4 306 2.59E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 Pfam PF00561 alpha/beta hydrolase fold 39 295 6.1E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS02445 26ee913db62752b19bfbd2d69095e0c5 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 10 313 2.3E-125 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 Gene3D G3DSA:3.30.465.10 60 174 3.0E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 SUPERFAMILY SSF56176 4 173 9.0E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 SUPERFAMILY SSF55447 179 260 4.91E-5 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 Gene3D G3DSA:3.30.43.10 1 59 3.9E-10 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 1.4E-40 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFA_RS15085 ec5b39959845d18b47b2608ef3b041a6 278 Gene3D G3DSA:3.30.390.50 178 275 9.0E-7 T 28-03-2018 AFA_RS11525 d9a16a1ee48bced22922ffe312ab5aea 295 SMART SM00244 20 185 6.2E-25 T 28-03-2018 IPR001107 Band 7 domain AFA_RS11525 d9a16a1ee48bced22922ffe312ab5aea 295 TIGRFAM TIGR01932 hflC: HflC protein 141 283 8.9E-48 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 AFA_RS11525 d9a16a1ee48bced22922ffe312ab5aea 295 Pfam PF01145 SPFH domain / Band 7 family 24 200 5.2E-27 T 28-03-2018 IPR001107 Band 7 domain AFA_RS11525 d9a16a1ee48bced22922ffe312ab5aea 295 SUPERFAMILY SSF117892 54 191 4.58E-24 T 28-03-2018 IPR001107 Band 7 domain AFA_RS11525 d9a16a1ee48bced22922ffe312ab5aea 295 PIRSF PIRSF005651 1 293 1.2E-88 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Gene3D G3DSA:3.90.220.20 204 351 4.9E-30 T 28-03-2018 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Pfam PF01420 Type I restriction modification DNA specificity domain 202 379 2.9E-27 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Pfam PF01420 Type I restriction modification DNA specificity domain 6 166 3.3E-23 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Gene3D G3DSA:3.90.220.20 2 155 4.0E-33 T 28-03-2018 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Gene3D G3DSA:1.10.287.1120 352 402 1.5E-9 T 28-03-2018 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 Gene3D G3DSA:1.10.287.1120 156 203 9.1E-13 T 28-03-2018 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 SUPERFAMILY SSF116734 193 397 6.38E-50 T 28-03-2018 AFA_RS02160 3043cff8ff6f267eefe25f1a68febd58 406 SUPERFAMILY SSF116734 4 193 9.65E-42 T 28-03-2018 AFA_RS16165 e1271ac0ad4b17822f13d400a3a62fd6 105 Gene3D G3DSA:1.10.220.30 11 86 3.9E-4 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS04275 459c30df22c295e85024452ac7588d28 629 Pfam PF00884 Sulfatase 269 536 7.5E-43 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS04275 459c30df22c295e85024452ac7588d28 629 SUPERFAMILY SSF53649 267 589 1.57E-65 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS04275 459c30df22c295e85024452ac7588d28 629 PIRSF PIRSF005091 38 608 4.0E-87 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like AFA_RS04275 459c30df22c295e85024452ac7588d28 629 Gene3D G3DSA:3.40.720.10 258 541 2.7E-55 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS00555 9aa7105d25cc1e26b2cc04d45ef91478 248 Pfam PF01925 Sulfite exporter TauE/SafE 13 242 1.0E-31 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 265 15.535 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 Gene3D G3DSA:3.30.420.40 92 277 2.1E-39 T 28-03-2018 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 SUPERFAMILY SSF53067 1 119 2.46E-15 T 28-03-2018 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 Pfam PF03309 Type III pantothenate kinase 3 217 9.7E-44 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 242 6.3E-17 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFA_RS01210 408de8d7fab1a0c88525a78920f87f49 278 SUPERFAMILY SSF53067 133 243 3.71E-19 T 28-03-2018 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 SUPERFAMILY SSF46785 6 87 2.45E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 Gene3D G3DSA:3.40.190.10 93 175 2.0E-15 T 28-03-2018 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 Gene3D G3DSA:1.10.10.10 2 92 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 SUPERFAMILY SSF53850 89 295 7.03E-25 T 28-03-2018 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 Pfam PF03466 LysR substrate binding domain 88 293 1.1E-23 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 5.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 Gene3D G3DSA:3.40.190.10 176 268 1.4E-11 T 28-03-2018 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02365 9e1fe07a14a83d4b991b3e824cb14658 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 PIRSF PIRSF002161 1 179 9.6E-64 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.906 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 8.7E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 Pfam PF00281 Ribosomal protein L5 25 80 9.0E-26 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 Gene3D G3DSA:3.30.1440.10 1 179 5.9E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18040 781c91d0d03d76b990622a544576542a 179 SUPERFAMILY SSF55282 3 179 1.15E-76 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17045 3bb348a6afce998b6c530b86c75a41a2 496 Pfam PF00860 Permease family 213 443 1.7E-65 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS17045 3bb348a6afce998b6c530b86c75a41a2 496 Pfam PF00860 Permease family 20 180 2.3E-33 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS17045 3bb348a6afce998b6c530b86c75a41a2 496 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 475 2.6E-112 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 PIRSF PIRSF000194 1 164 3.4E-59 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 Pfam PF00186 Dihydrofolate reductase 7 162 6.3E-56 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 SUPERFAMILY SSF53597 6 163 1.96E-57 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 18 40 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 PRINTS PR00070 Dihydrofolate reductase signature 32 40 2.5E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 PRINTS PR00070 Dihydrofolate reductase signature 18 28 2.5E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 PRINTS PR00070 Dihydrofolate reductase signature 45 56 2.5E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 PRINTS PR00070 Dihydrofolate reductase signature 96 110 2.5E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 Gene3D G3DSA:3.40.430.10 1 43 1.4E-13 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AFA_RS02595 35df234a5458e4a7c9ed4cc66d601aa2 164 Gene3D G3DSA:3.40.430.10 44 163 3.6E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Pfam PF00072 Response regulator receiver domain 7 116 2.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 SUPERFAMILY SSF52540 146 375 1.82E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Gene3D G3DSA:3.40.50.300 141 317 1.1E-23 T 28-03-2018 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 SMART SM00448 5 116 1.1E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 2.3E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 2.3E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Pfam PF02954 Bacterial regulatory protein, Fis family 399 439 3.7E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Gene3D G3DSA:1.10.10.60 401 443 1.1E-13 T 28-03-2018 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 SUPERFAMILY SSF46689 359 441 2.4E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 SMART SM00382 166 314 5.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 SUPERFAMILY SSF52172 4 189 1.57E-44 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Gene3D G3DSA:3.40.50.2300 2 140 2.1E-34 T 28-03-2018 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Pfam PF00158 Sigma-54 interaction domain 147 312 1.1E-62 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFA_RS09155 5f1fd6e21988cda1e81357a9581695ef 444 Gene3D G3DSA:1.10.8.60 318 400 1.7E-19 T 28-03-2018 AFA_RS15660 3f983bb50d0a6e3230af6b1d07ddad23 165 SUPERFAMILY SSF52833 5 163 1.05E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS15660 3f983bb50d0a6e3230af6b1d07ddad23 165 ProSitePatterns PS00194 Thioredoxin family active site. 57 75 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFA_RS15660 3f983bb50d0a6e3230af6b1d07ddad23 165 Pfam PF08534 Redoxin 36 159 2.3E-17 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFA_RS15660 3f983bb50d0a6e3230af6b1d07ddad23 165 Gene3D G3DSA:3.40.30.10 20 165 5.3E-29 T 28-03-2018 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 Pfam PF01170 Putative RNA methylase family UPF0020 612 815 5.6E-48 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 Gene3D G3DSA:3.40.50.150 610 831 1.6E-30 T 28-03-2018 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 750 756 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 SMART SM00981 506 604 5.4E-15 T 28-03-2018 IPR004114 THUMP domain GO:0003723 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 SUPERFAMILY SSF53335 599 667 1.15E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 SUPERFAMILY SSF53335 704 818 1.15E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 Pfam PF02926 THUMP domain 490 603 3.8E-7 T 28-03-2018 IPR004114 THUMP domain GO:0003723 AFA_RS12860 cade4d4139002ec8048bb030430b5144 843 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 645 656 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 189 209 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 234 259 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 101 120 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 210 231 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 81 101 7.3E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 182 194 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 250 260 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 60 69 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 120 132 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 132 146 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 160 172 4.7E-30 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 Pfam PF00813 FliP family 64 256 3.4E-79 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 237 249 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 189 204 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFA_RS05910 c6015ecb9d821bfcae43c3d2525d3be4 262 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 64 260 3.4E-91 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 33 105 8.1E-14 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 SUPERFAMILY SSF56349 127 332 4.12E-46 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 Gene3D G3DSA:1.10.443.10 135 328 1.5E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 28 334 53.145 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 Gene3D G3DSA:1.10.150.130 22 134 2.2E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 Pfam PF00589 Phage integrase family 133 320 1.1E-36 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS01995 93e2a6c2139ec90fce92096d83e66bd8 346 SUPERFAMILY SSF47823 29 118 2.35E-12 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal AFA_RS14575 3250f0728422124b87447f380e4079d6 361 Pfam PF00005 ABC transporter 22 170 2.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS14575 3250f0728422124b87447f380e4079d6 361 Pfam PF08402 TOBE domain 285 359 5.7E-13 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS14575 3250f0728422124b87447f380e4079d6 361 SMART SM00382 31 228 6.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14575 3250f0728422124b87447f380e4079d6 361 SUPERFAMILY SSF52540 3 252 1.05E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14575 3250f0728422124b87447f380e4079d6 361 Gene3D G3DSA:2.40.50.100 256 297 4.1E-4 T 28-03-2018 AFA_RS14575 3250f0728422124b87447f380e4079d6 361 SUPERFAMILY SSF50331 270 359 6.8E-14 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS14575 3250f0728422124b87447f380e4079d6 361 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS14575 3250f0728422124b87447f380e4079d6 361 Gene3D G3DSA:3.40.50.300 1 255 9.7E-68 T 28-03-2018 AFA_RS14575 3250f0728422124b87447f380e4079d6 361 Gene3D G3DSA:2.40.50.140 298 352 9.1E-8 T 28-03-2018 AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 Gene3D G3DSA:3.40.190.10 94 181 1.5E-13 T 28-03-2018 AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 Gene3D G3DSA:3.40.190.10 182 269 3.6E-24 T 28-03-2018 AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 1.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 Gene3D G3DSA:1.10.10.10 3 89 4.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 Pfam PF03466 LysR substrate binding domain 94 300 1.8E-41 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 SUPERFAMILY SSF46785 11 93 5.08E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01910 ab59d73e95bd3b67a5114096bc6ad2e3 313 SUPERFAMILY SSF53850 95 304 1.63E-43 T 28-03-2018 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 Pfam PF01380 SIS domain 47 177 4.6E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 Pfam PF00571 CBS domain 206 263 2.4E-6 T 28-03-2018 IPR000644 CBS domain AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 Pfam PF00571 CBS domain 273 326 4.3E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 Gene3D G3DSA:3.40.50.10490 7 204 7.1E-55 T 28-03-2018 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 Gene3D G3DSA:3.10.580.10 205 327 7.8E-21 T 28-03-2018 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 PIRSF PIRSF004692 1 329 1.3E-126 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 319 1.1E-104 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 SUPERFAMILY SSF53697 13 327 1.29E-66 T 28-03-2018 AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 SMART SM00116 280 328 14.0 T 28-03-2018 IPR000644 CBS domain AFA_RS16325 a4f2b33fbdd9a2a7fd036bddf30e223b 329 SMART SM00116 215 263 0.17 T 28-03-2018 IPR000644 CBS domain AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 Pfam PF13662 Toprim domain 87 176 5.5E-23 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 Pfam PF02132 RecR protein 45 83 9.0E-12 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 Gene3D G3DSA:3.40.1360.10 82 175 6.7E-34 T 28-03-2018 AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 SMART SM00493 85 170 6.9E-7 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 TIGRFAM TIGR00615 recR: recombination protein RecR 9 201 1.4E-65 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 Hamap MF_00017 Recombination protein RecR [recR]. 1 203 88.148 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFA_RS04100 21d4883f9e2a2041abadf5ed046f2cdc 203 SUPERFAMILY SSF111304 9 201 3.14E-68 T 28-03-2018 IPR023627 Recombination protein RecR AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 Gene3D G3DSA:3.90.226.10 2 271 9.8E-35 T 28-03-2018 AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 SUPERFAMILY SSF52096 7 203 2.68E-33 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 69 83 2.4E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 104 122 2.4E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 2.4E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 Pfam PF01039 Carboxyl transferase domain 9 191 2.4E-14 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 AFA_RS04485 e286f1042cb4f4df50a0401b289a1f22 300 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 2 253 3.5E-106 T 28-03-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 414 44.168 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 SUPERFAMILY SSF55205 1 415 1.8E-141 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 Gene3D G3DSA:3.65.10.10 219 416 3.2E-47 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 413 2.2E-175 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 404 5.4E-107 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS17130 35c80cbe1275ce21ed18e231f6098da2 419 Gene3D G3DSA:3.65.10.10 21 218 3.7E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 2.0E-19 T 28-03-2018 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.6E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.6E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.6E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 SUPERFAMILY SSF54909 63 150 3.62E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 Gene3D G3DSA:3.30.70.920 55 147 3.8E-22 T 28-03-2018 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 SMART SM00344 2 111 5.4E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 Gene3D G3DSA:1.10.10.10 3 54 1.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 SUPERFAMILY SSF46785 1 60 4.01E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 1.0E-19 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS07220 58779f00b7b2910dc56bdcdafe2d9d4c 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 9.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 SUPERFAMILY SSF46785 3 112 1.41E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 Pfam PF03466 LysR substrate binding domain 88 294 8.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 Gene3D G3DSA:1.10.10.10 3 93 2.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 Gene3D G3DSA:3.40.190.10 178 266 1.1E-16 T 28-03-2018 AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 Gene3D G3DSA:3.40.190.10 94 177 9.3E-20 T 28-03-2018 AFA_RS16515 6f11e01d2aceceac14f7d64315cde2da 295 SUPERFAMILY SSF53850 89 294 8.54E-37 T 28-03-2018 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 Pfam PF00708 Acylphosphatase 7 91 4.3E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 Gene3D G3DSA:3.30.70.100 1 92 1.5E-25 T 28-03-2018 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 PRINTS PR00112 Acylphosphatase signature 27 52 1.4E-6 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 PRINTS PR00112 Acylphosphatase signature 6 21 1.4E-6 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFA_RS01015 64d71ac31a8a2aebea2781b28e25772e 92 SUPERFAMILY SSF54975 4 92 1.68E-25 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 Gene3D G3DSA:3.40.50.150 27 252 9.9E-42 T 28-03-2018 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 43 58 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 SUPERFAMILY SSF53335 25 251 1.88E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 23 254 35.533 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 32 252 4.9E-75 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 Pfam PF01209 ubiE/COQ5 methyltransferase family 28 253 1.5E-83 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFA_RS16220 19512664c10b5e61a1b8181a06e29a49 256 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 163 177 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFA_RS13930 ea49c7ca16b408971eefdecf919ec2cf 315 Gene3D G3DSA:3.40.830.10 2 308 3.0E-46 T 28-03-2018 AFA_RS13930 ea49c7ca16b408971eefdecf919ec2cf 315 SUPERFAMILY SSF53213 230 311 1.31E-67 T 28-03-2018 AFA_RS13930 ea49c7ca16b408971eefdecf919ec2cf 315 SUPERFAMILY SSF53213 6 185 1.31E-67 T 28-03-2018 AFA_RS13930 ea49c7ca16b408971eefdecf919ec2cf 315 Hamap MF_01653 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase [mhpB]. 1 313 50.582 T 28-03-2018 IPR023789 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase GO:0005506|GO:0019439|GO:0047070|GO:0055114 KEGG: 00360+1.13.11.16|MetaCyc: PWY-6690 AFA_RS13930 ea49c7ca16b408971eefdecf919ec2cf 315 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 306 6.2E-62 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 14 231 5.3E-68 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 SUPERFAMILY SSF56300 185 216 3.6E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 SUPERFAMILY SSF56300 10 132 3.6E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 Pfam PF00149 Calcineurin-like phosphoesterase 10 209 9.3E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 Gene3D G3DSA:3.60.21.10 11 250 1.4E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS04535 7551b27a0999b6cab3d18dd680b9887c 268 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 257 88.491 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AFA_RS08190 3a5f3fb406c8ec075d37c71e6977d9b9 395 Pfam PF07690 Major Facilitator Superfamily 25 327 1.6E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS08190 3a5f3fb406c8ec075d37c71e6977d9b9 395 Gene3D G3DSA:1.20.1250.20 204 393 3.7E-17 T 28-03-2018 AFA_RS08190 3a5f3fb406c8ec075d37c71e6977d9b9 395 SUPERFAMILY SSF103473 7 387 1.44E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS08190 3a5f3fb406c8ec075d37c71e6977d9b9 395 Gene3D G3DSA:1.20.1250.20 2 196 3.2E-22 T 28-03-2018 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 Pfam PF00005 ABC transporter 378 531 6.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 Gene3D G3DSA:3.40.50.300 347 604 3.2E-74 T 28-03-2018 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 SMART SM00382 386 577 1.8E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 Pfam PF00664 ABC transporter transmembrane region 41 307 7.4E-17 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 Gene3D G3DSA:1.20.1560.10 14 346 2.8E-32 T 28-03-2018 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 SUPERFAMILY SSF52540 350 601 1.33E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 SUPERFAMILY SSF90123 507 522 1.26E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS04425 01a56ac6705f47a57ea5004de604157a 614 SUPERFAMILY SSF90123 28 324 1.26E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS05985 87c0fb9bca2c3bd96244d481de42baa5 143 Gene3D G3DSA:1.20.120.340 11 137 5.7E-32 T 28-03-2018 AFA_RS05985 87c0fb9bca2c3bd96244d481de42baa5 143 PIRSF PIRSF039090 10 143 1.3E-32 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 AFA_RS05985 87c0fb9bca2c3bd96244d481de42baa5 143 Pfam PF02561 Flagellar protein FliS 16 132 1.1E-30 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 AFA_RS05985 87c0fb9bca2c3bd96244d481de42baa5 143 SUPERFAMILY SSF101116 17 132 3.14E-30 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 AFA_RS05985 87c0fb9bca2c3bd96244d481de42baa5 143 TIGRFAM TIGR00208 fliS: flagellar protein FliS 12 134 1.2E-30 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 AFA_RS01320 ed9d1e029d399b7e65835161f7839fbe 129 Pfam PF02036 SCP-2 sterol transfer family 9 94 6.6E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS01320 ed9d1e029d399b7e65835161f7839fbe 129 Gene3D G3DSA:3.30.1050.10 1 104 2.4E-12 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS01320 ed9d1e029d399b7e65835161f7839fbe 129 SUPERFAMILY SSF55718 12 101 3.3E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 SUPERFAMILY SSF54427 16 120 9.84E-10 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 Gene3D G3DSA:3.50.50.60 170 321 2.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 305 2.6E-7 T 28-03-2018 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 194 2.6E-7 T 28-03-2018 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 362 2.6E-7 T 28-03-2018 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 Gene3D G3DSA:3.50.50.60 322 508 1.0E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 Gene3D G3DSA:3.10.450.50 3 127 6.2E-9 T 28-03-2018 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 174 369 2.2E-20 T 28-03-2018 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 SUPERFAMILY SSF51905 465 584 5.62E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS17440 18ec04f02471fb6dfa6b6aa738cb44d2 605 SUPERFAMILY SSF51905 173 368 5.62E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 Pfam PF02545 Maf-like protein 6 195 5.0E-48 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 SUPERFAMILY SSF52972 3 194 6.15E-51 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 Gene3D G3DSA:3.90.950.10 3 201 7.0E-58 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 194 1.0E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 PIRSF PIRSF006305 3 203 4.3E-47 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS12730 d89b541f8b6ad734647ce850ccdef7c1 205 Hamap MF_00528 Septum formation protein Maf [maf]. 5 201 27.733 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS13065 4f4f033c3421841868146488798fb987 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 76 284 3.2E-51 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFA_RS13065 4f4f033c3421841868146488798fb987 294 Gene3D G3DSA:2.10.109.10 86 293 5.9E-55 T 28-03-2018 AFA_RS13065 4f4f033c3421841868146488798fb987 294 Pfam PF00717 Peptidase S24-like 96 177 1.3E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS13065 4f4f033c3421841868146488798fb987 294 SUPERFAMILY SSF51306 88 290 7.06E-67 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS13065 4f4f033c3421841868146488798fb987 294 ProSitePatterns PS00761 Signal peptidases I signature 3. 249 262 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 AFA_RS13065 4f4f033c3421841868146488798fb987 294 Pfam PF10502 Signal peptidase, peptidase S26 242 281 3.9E-8 T 28-03-2018 IPR019533 Peptidase S26 AFA_RS13065 4f4f033c3421841868146488798fb987 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 99 106 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 AFA_RS13065 4f4f033c3421841868146488798fb987 294 ProSitePatterns PS00760 Signal peptidases I lysine active site. 156 168 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 AFA_RS13065 4f4f033c3421841868146488798fb987 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 90 106 2.2E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFA_RS13065 4f4f033c3421841868146488798fb987 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 154 166 2.2E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFA_RS13065 4f4f033c3421841868146488798fb987 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 244 263 2.2E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFA_RS13835 7286e143eb3fbdb69783a46aecb2846c 391 SUPERFAMILY SSF103473 2 382 4.19E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13835 7286e143eb3fbdb69783a46aecb2846c 391 Pfam PF07690 Major Facilitator Superfamily 6 344 4.0E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS13835 7286e143eb3fbdb69783a46aecb2846c 391 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 1 382 1.9E-64 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AFA_RS13835 7286e143eb3fbdb69783a46aecb2846c 391 Gene3D G3DSA:1.20.1250.20 1 188 9.5E-29 T 28-03-2018 AFA_RS13835 7286e143eb3fbdb69783a46aecb2846c 391 Gene3D G3DSA:1.20.1250.20 189 385 3.0E-11 T 28-03-2018 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 SUPERFAMILY SSF51338 26 82 1.48E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 SUPERFAMILY SSF51338 351 446 4.65E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 SUPERFAMILY SSF51556 70 370 1.29E-62 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 Pfam PF01979 Amidohydrolase family 68 418 1.4E-40 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 Gene3D G3DSA:3.20.20.140 79 358 1.7E-41 T 28-03-2018 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 Gene3D G3DSA:2.30.40.10 359 422 6.7E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS08605 5e9250480635c3bfcedd57e43e85915f 472 Gene3D G3DSA:2.30.40.10 10 78 1.3E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS07865 d8640042a747324bbf5da8022c4e0015 62 Gene3D G3DSA:1.10.1220.10 1 42 9.4E-11 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS07865 d8640042a747324bbf5da8022c4e0015 62 SUPERFAMILY SSF47598 2 49 7.56E-14 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 SMART SM00478 57 213 3.5E-11 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 194 2.1E-12 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 SUPERFAMILY SSF48150 44 211 8.72E-42 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Gene3D G3DSA:1.10.340.30 45 160 2.4E-24 T 28-03-2018 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 326 405 1.5E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Gene3D G3DSA:1.10.1670.10 162 216 4.1E-15 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 375 381 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Gene3D G3DSA:1.10.10.10 323 407 3.3E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15620 b255290c348861c607625fd73f311bbd 407 SUPERFAMILY SSF53155 245 322 3.14E-19 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 249 321 9.4E-8 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 Gene3D G3DSA:3.30.160.70 231 322 9.1E-17 T 28-03-2018 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 325 404 6.2E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS15620 b255290c348861c607625fd73f311bbd 407 SUPERFAMILY SSF46767 324 405 1.7E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 1.4E-16 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 Gene3D G3DSA:1.20.1050.10 89 202 1.6E-21 T 28-03-2018 AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 Pfam PF13410 Glutathione S-transferase, C-terminal domain 119 182 2.5E-9 T 28-03-2018 AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 Gene3D G3DSA:3.40.30.10 1 88 9.0E-27 T 28-03-2018 AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 SUPERFAMILY SSF52833 1 101 9.05E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS17225 ad2f673658534fd6c586066d5e34a2e3 202 SUPERFAMILY SSF47616 73 201 2.51E-24 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS05130 9ba06d5c6cc36cb5ed6726dce37377fb 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 226 1.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05130 9ba06d5c6cc36cb5ed6726dce37377fb 233 Gene3D G3DSA:1.10.3720.10 15 229 4.6E-35 T 28-03-2018 AFA_RS05130 9ba06d5c6cc36cb5ed6726dce37377fb 233 SUPERFAMILY SSF161098 17 213 3.14E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05130 9ba06d5c6cc36cb5ed6726dce37377fb 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 121 2.0E-15 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 PIRSF PIRSF002162 1 177 3.3E-46 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 Gene3D G3DSA:3.90.930.12 5 85 1.5E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 SUPERFAMILY SSF56053 1 82 2.88E-23 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.45 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 Gene3D G3DSA:3.90.930.12 86 177 7.0E-38 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 SUPERFAMILY SSF56053 83 177 7.77E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.3E-71 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 Pfam PF00347 Ribosomal protein L6 12 82 1.2E-14 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18025 00aa5528c30a0faeeb9254c86e4665ca 177 Pfam PF00347 Ribosomal protein L6 90 164 2.5E-17 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17765 28614a7c9e6270e54f29f6473bd3c24e 340 Gene3D G3DSA:3.40.1390.30 41 138 3.4E-10 T 28-03-2018 AFA_RS17765 28614a7c9e6270e54f29f6473bd3c24e 340 SUPERFAMILY SSF102705 50 93 1.23E-9 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFA_RS17765 28614a7c9e6270e54f29f6473bd3c24e 340 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 50 92 1.3E-7 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFA_RS11320 3c0e4d8fe80962c51af7c024c086b4f4 266 Gene3D G3DSA:3.40.50.80 135 265 3.7E-30 T 28-03-2018 AFA_RS11320 3c0e4d8fe80962c51af7c024c086b4f4 266 Pfam PF04954 Siderophore-interacting protein 142 256 1.2E-24 T 28-03-2018 IPR007037 Siderophore-interacting protein AFA_RS11320 3c0e4d8fe80962c51af7c024c086b4f4 266 Gene3D G3DSA:2.40.30.10 9 134 1.0E-31 T 28-03-2018 AFA_RS11320 3c0e4d8fe80962c51af7c024c086b4f4 266 SUPERFAMILY SSF63380 6 137 3.21E-12 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS11320 3c0e4d8fe80962c51af7c024c086b4f4 266 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 134 1.2E-36 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting AFA_RS17125 7f5e4002caa9a7d5d141ea1c098e8e9c 82 Pfam PF01722 BolA-like protein 23 75 1.2E-20 T 28-03-2018 IPR002634 BolA protein AFA_RS17125 7f5e4002caa9a7d5d141ea1c098e8e9c 82 Gene3D G3DSA:3.30.300.90 2 81 2.9E-29 T 28-03-2018 AFA_RS17125 7f5e4002caa9a7d5d141ea1c098e8e9c 82 SUPERFAMILY SSF82657 2 79 7.85E-29 T 28-03-2018 IPR002634 BolA protein AFA_RS17125 7f5e4002caa9a7d5d141ea1c098e8e9c 82 PIRSF PIRSF003113 1 82 2.2E-24 T 28-03-2018 IPR002634 BolA protein AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 1.4E-56 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 34.79 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 58 4.3E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 68 0.008 T 28-03-2018 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 Gene3D G3DSA:3.40.50.620 1 158 7.0E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 Pfam PF01467 Cytidylyltransferase-like 5 133 1.7E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.0E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.0E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.0E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.0E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.0E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFA_RS14900 a995ec3859accfb0bf46366113501a41 168 SUPERFAMILY SSF52374 1 155 1.15E-43 T 28-03-2018 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 530 644 3.3E-27 T 28-03-2018 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 SUPERFAMILY SSF48239 1494 1747 2.82E-7 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1025 1208 3.5E-20 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Pfam PF00207 Alpha-2-macroglobulin family 1268 1355 1.9E-12 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 SMART SM01360 1266 1356 6.6E-22 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Gene3D G3DSA:2.60.40.10 1157 1316 3.5E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Gene3D G3DSA:2.60.40.10 865 1007 4.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 SMART SM01359 1025 1208 1.7E-37 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Gene3D G3DSA:2.60.40.10 1318 1431 1.4E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Gene3D G3DSA:2.60.40.10 1830 1942 0.011 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS11080 b594a2fb34cfe24da23a2d7897700a72 1969 Pfam PF01835 MG2 domain 652 751 9.3E-14 T 28-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 AFA_RS03985 e62dae113d0d8109aef5c568300ee917 494 Gene3D G3DSA:3.40.605.10 10 279 3.7E-86 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS03985 e62dae113d0d8109aef5c568300ee917 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS03985 e62dae113d0d8109aef5c568300ee917 494 Gene3D G3DSA:3.40.309.10 280 473 1.6E-62 T 28-03-2018 AFA_RS03985 e62dae113d0d8109aef5c568300ee917 494 Pfam PF00171 Aldehyde dehydrogenase family 34 489 3.2E-159 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS03985 e62dae113d0d8109aef5c568300ee917 494 SUPERFAMILY SSF53720 17 491 5.63E-148 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 SMART SM00346 16 106 3.6E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 Gene3D G3DSA:1.10.10.10 7 77 7.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 Pfam PF09339 IclR helix-turn-helix domain 18 68 7.9E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 Pfam PF01614 Bacterial transcriptional regulator 135 262 2.0E-17 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 Gene3D G3DSA:3.30.450.40 89 269 3.0E-41 T 28-03-2018 IPR029016 GAF domain-like AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 SUPERFAMILY SSF55781 74 267 1.77E-37 T 28-03-2018 IPR029016 GAF domain-like AFA_RS14880 44d21fd012c2a36cbc68e2a5d9a0e800 279 SUPERFAMILY SSF46785 16 89 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13720 40380d3bc066f622311d3b2e182a03e6 160 SUPERFAMILY SSF46785 10 135 4.88E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13720 40380d3bc066f622311d3b2e182a03e6 160 SMART SM00347 28 122 0.0013 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS13720 40380d3bc066f622311d3b2e182a03e6 160 Pfam PF01047 MarR family 37 92 1.5E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS13720 40380d3bc066f622311d3b2e182a03e6 160 Gene3D G3DSA:1.10.10.10 13 149 4.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 Pfam PF00043 Glutathione S-transferase, C-terminal domain 112 192 7.7E-13 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 SUPERFAMILY SSF47616 73 200 3.14E-35 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 Gene3D G3DSA:1.20.1050.10 97 206 8.3E-31 T 28-03-2018 AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 Gene3D G3DSA:3.40.30.10 1 96 7.3E-29 T 28-03-2018 AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 SUPERFAMILY SSF52833 4 79 2.88E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS17720 772953f9abf5179ce2478105cbef844e 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 9 76 6.3E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Gene3D G3DSA:3.40.50.800 536 640 5.1E-26 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 635 1.9E-214 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 533 2.2E-40 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Pfam PF03129 Anticodon binding domain 545 634 3.2E-18 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 SUPERFAMILY SSF52954 534 638 2.57E-29 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 2.0E-15 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 SUPERFAMILY SSF55186 69 245 1.14E-66 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 638 33.961 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Gene3D G3DSA:3.30.980.10 75 231 4.7E-44 T 28-03-2018 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 SUPERFAMILY SSF55681 247 530 1.15E-98 T 28-03-2018 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 SMART SM00863 174 223 1.1E-25 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Pfam PF02824 TGS domain 2 66 3.8E-7 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Gene3D G3DSA:3.30.930.10 232 535 2.9E-118 T 28-03-2018 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 4.1E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 4.1E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 4.1E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 4.1E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 4.1E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 SUPERFAMILY SSF81271 2 66 2.06E-10 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFA_RS08665 114f780a04874b71f53493285d40f6f7 640 Gene3D G3DSA:3.10.20.30 1 69 3.5E-14 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS16190 5091a0be0de15972221f783a37f0c803 440 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 19 437 2.4E-90 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 AFA_RS16190 5091a0be0de15972221f783a37f0c803 440 Pfam PF02321 Outer membrane efflux protein 23 209 3.5E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS16190 5091a0be0de15972221f783a37f0c803 440 Pfam PF02321 Outer membrane efflux protein 233 422 3.0E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS16190 5091a0be0de15972221f783a37f0c803 440 Gene3D G3DSA:1.20.1600.10 12 429 3.3E-62 T 28-03-2018 AFA_RS16190 5091a0be0de15972221f783a37f0c803 440 SUPERFAMILY SSF56954 4 427 1.31E-75 T 28-03-2018 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Gene3D G3DSA:3.40.50.980 218 373 3.5E-39 T 28-03-2018 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 546 3.9E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Gene3D G3DSA:2.30.38.10 374 456 1.3E-29 T 28-03-2018 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Pfam PF00501 AMP-binding enzyme 31 463 2.1E-109 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 SUPERFAMILY SSF56801 19 553 4.06E-150 T 28-03-2018 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Gene3D G3DSA:3.30.300.30 457 554 3.2E-25 T 28-03-2018 AFA_RS18175 2969a69e83fccb5da4f33e52b0e26c2d 554 Gene3D G3DSA:3.40.50.980 22 217 4.3E-41 T 28-03-2018 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 SUPERFAMILY SSF142984 341 422 1.23E-20 T 28-03-2018 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 SUPERFAMILY SSF140490 424 509 5.62E-28 T 28-03-2018 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 440 451 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 146 317 3.2E-45 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 429 509 2.7E-29 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 SMART SM00928 427 472 4.5E-14 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 SUPERFAMILY SSF142019 98 338 7.19E-88 T 28-03-2018 AFA_RS03045 9f79680a396f380ce782763bff03080d 522 SUPERFAMILY SSF52833 4 87 8.95E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS03765 b874c7950366b9c7452b5794e0cdd2e4 219 Gene3D G3DSA:1.10.3720.10 5 219 2.0E-29 T 28-03-2018 AFA_RS03765 b874c7950366b9c7452b5794e0cdd2e4 219 SUPERFAMILY SSF161098 10 205 1.96E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS03765 b874c7950366b9c7452b5794e0cdd2e4 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 218 3.9E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 SUPERFAMILY SSF48029 7 108 5.49E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Pfam PF14842 FliG N-terminal domain 10 104 4.8E-27 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 11 328 2.6E-110 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 5.0E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 SUPERFAMILY SSF48029 118 328 3.14E-63 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 PIRSF PIRSF003161 2 336 8.4E-112 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Pfam PF01706 FliG C-terminal domain 221 327 4.0E-37 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Pfam PF14841 FliG middle domain 120 193 4.0E-25 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Gene3D G3DSA:1.10.220.30 198 336 1.4E-27 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Gene3D G3DSA:1.10.220.30 9 70 1.0E-8 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS05955 469c1e1e5c491b497b01267c5c1f6e3c 336 Gene3D G3DSA:1.10.220.30 71 193 5.2E-19 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Gene3D G3DSA:1.20.1270.10 533 619 7.5E-21 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 SUPERFAMILY SSF53067 188 383 9.88E-68 T 28-03-2018 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 54 62 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 366 386 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 199 209 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 138 158 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 335 351 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 389 408 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 PRINTS PR00301 70kDa heat shock protein signature 470 486 5.0E-80 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Gene3D G3DSA:2.60.34.10 391 532 4.6E-65 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Gene3D G3DSA:3.30.420.40 198 367 1.4E-47 T 28-03-2018 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 SUPERFAMILY SSF100920 386 541 4.84E-60 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Pfam PF00012 Hsp70 protein 4 604 9.6E-263 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 SUPERFAMILY SSF100934 508 607 5.1E-20 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.3E-285 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 SUPERFAMILY SSF53067 4 183 5.18E-65 T 28-03-2018 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Gene3D G3DSA:3.30.420.40 1 197 1.8E-81 T 28-03-2018 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 638 36.508 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 AFA_RS13750 710ebbd8fca565c8f7d9bf9950249b59 642 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFA_RS16385 3f3fa6c21977152ffab3e86afe8c0798 200 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 5 195 36.847 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 AFA_RS16385 3f3fa6c21977152ffab3e86afe8c0798 200 Gene3D G3DSA:3.40.50.10490 6 196 2.6E-41 T 28-03-2018 AFA_RS16385 3f3fa6c21977152ffab3e86afe8c0798 200 SUPERFAMILY SSF53697 7 194 9.71E-57 T 28-03-2018 AFA_RS16385 3f3fa6c21977152ffab3e86afe8c0798 200 Pfam PF13580 SIS domain 15 149 5.4E-36 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS05825 c0566d657f0f0efa623c15396e7f5003 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 130 2.6E-10 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFA_RS05825 c0566d657f0f0efa623c15396e7f5003 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site AFA_RS05825 c0566d657f0f0efa623c15396e7f5003 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 134 9.0E-49 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 AFA_RS05825 c0566d657f0f0efa623c15396e7f5003 134 Pfam PF00460 Flagella basal body rod protein 7 37 1.1E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 Pfam PF01765 Ribosome recycling factor 21 184 1.3E-62 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 Gene3D G3DSA:1.10.132.20 76 186 3.0E-38 T 28-03-2018 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 Gene3D G3DSA:1.10.132.20 3 75 3.5E-8 T 28-03-2018 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.741 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 1.7E-68 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFA_RS10195 5731c1a69f201ed866ddea4ed88636a9 186 SUPERFAMILY SSF55194 5 185 2.09E-69 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Hamap MF_01895 Ribonuclease R [rnr]. 48 751 52.814 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SUPERFAMILY SSF50249 78 155 4.61E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Pfam PF00773 RNB domain 269 608 2.0E-99 T 28-03-2018 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 TIGRFAM TIGR02063 RNase_R: ribonuclease R 30 752 9.3E-245 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SUPERFAMILY SSF50249 670 750 1.09E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Pfam PF00575 S1 RNA binding domain 669 748 2.5E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 85 751 6.1E-198 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Gene3D G3DSA:2.40.50.140 667 752 2.8E-19 T 28-03-2018 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SMART SM00357 96 154 2.9E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SMART SM00316 668 751 5.7E-13 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Pfam PF08206 Ribonuclease B OB domain 97 153 6.6E-18 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 ProSitePatterns PS01175 Ribonuclease II family signature. 576 600 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Gene3D G3DSA:1.10.10.10 24 87 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SUPERFAMILY SSF50249 555 669 8.0E-132 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SUPERFAMILY SSF50249 197 519 8.0E-132 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 Gene3D G3DSA:2.40.50.140 88 214 0.0014 T 28-03-2018 AFA_RS11290 4d2c822234dea660fc7e8944f1f4781d 825 SMART SM00955 269 609 7.2E-173 T 28-03-2018 AFA_RS17735 cf1e8740580df4993825fa81b9e6e157 347 SUPERFAMILY SSF55961 103 339 1.54E-42 T 28-03-2018 AFA_RS17735 cf1e8740580df4993825fa81b9e6e157 347 Gene3D G3DSA:3.90.380.10 107 343 2.4E-46 T 28-03-2018 AFA_RS17735 cf1e8740580df4993825fa81b9e6e157 347 Gene3D G3DSA:2.102.10.10 2 106 7.4E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS17735 cf1e8740580df4993825fa81b9e6e157 347 Pfam PF00355 Rieske [2Fe-2S] domain 15 90 8.9E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS17735 cf1e8740580df4993825fa81b9e6e157 347 SUPERFAMILY SSF50022 2 112 3.01E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SMART SM00491 503 633 2.2E-36 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SUPERFAMILY SSF52540 474 623 1.42E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SUPERFAMILY SSF52540 592 620 6.94E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SUPERFAMILY SSF52540 191 248 6.94E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SUPERFAMILY SSF52540 16 113 6.94E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 Pfam PF13307 Helicase C-terminal domain 484 646 4.2E-35 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 SMART SM00487 21 284 0.006 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 Gene3D G3DSA:3.40.50.300 23 444 1.2E-29 T 28-03-2018 AFA_RS04930 bde0f79fc096febab2079498462bc0c9 684 Gene3D G3DSA:3.40.50.300 472 675 1.3E-14 T 28-03-2018 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 2 460 1.0E-204 T 28-03-2018 IPR012831 Precorrin 3B synthase CobZ AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 Pfam PF00890 FAD binding domain 3 432 2.7E-28 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 Gene3D G3DSA:3.90.700.10 260 399 1.0E-28 T 28-03-2018 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 Gene3D G3DSA:3.50.50.60 1 208 2.7E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 SUPERFAMILY SSF51905 2 191 5.5E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 SUPERFAMILY SSF51905 365 457 5.5E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09165 dc2e3f37b2b192321cf9d69cbcb21084 461 SUPERFAMILY SSF56425 251 397 1.26E-22 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 Pfam PF08281 Sigma-70, region 4 113 160 1.7E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 Gene3D G3DSA:1.10.1740.10 2 75 2.1E-13 T 28-03-2018 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 Pfam PF04542 Sigma-70 region 2 13 78 1.4E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 SUPERFAMILY SSF88659 87 164 2.83E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 158 3.4E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 Gene3D G3DSA:1.10.10.10 76 168 2.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00440 d8c4b5b3b1212457794747871d43c7bf 174 SUPERFAMILY SSF88946 7 97 9.02E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 SUPERFAMILY SSF46934 3 56 9.8E-15 T 28-03-2018 IPR009060 UBA-like GO:0005515 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 Gene3D G3DSA:1.10.8.10 1 56 4.8E-19 T 28-03-2018 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 Gene3D G3DSA:3.30.479.20 58 156 3.1E-23 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 Gene3D G3DSA:3.30.479.20 157 288 7.5E-45 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 SUPERFAMILY SSF54713 151 290 1.27E-46 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 Pfam PF00889 Elongation factor TS 74 272 4.0E-67 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 289 2.5E-89 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 289 75.615 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS10205 caeb4daf51f30fc9a14e774e34b1257e 292 SUPERFAMILY SSF54713 56 147 1.07E-23 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFA_RS02440 5836cbed28a294dce026677fe8dcc249 66 SUPERFAMILY SSF54285 2 65 4.65E-18 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFA_RS02440 5836cbed28a294dce026677fe8dcc249 66 Gene3D G3DSA:3.10.20.30 1 66 4.7E-24 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS02440 5836cbed28a294dce026677fe8dcc249 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 3.1E-23 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis AFA_RS02440 5836cbed28a294dce026677fe8dcc249 66 Pfam PF02597 ThiS family 3 66 1.4E-16 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 AFA_RS18115 249e3db1af828a6ff6df27bd08813af9 282 Pfam PF00005 ABC transporter 18 172 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18115 249e3db1af828a6ff6df27bd08813af9 282 SUPERFAMILY SSF52540 2 230 1.39E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18115 249e3db1af828a6ff6df27bd08813af9 282 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS18115 249e3db1af828a6ff6df27bd08813af9 282 Gene3D G3DSA:3.40.50.300 1 244 1.9E-61 T 28-03-2018 AFA_RS18115 249e3db1af828a6ff6df27bd08813af9 282 SMART SM00382 27 221 4.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00990 2abd5adb4b39880892009b4507573668 294 SUPERFAMILY SSF53850 90 286 1.72E-25 T 28-03-2018 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 Gene3D G3DSA:3.40.190.10 91 221 3.1E-18 T 28-03-2018 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00990 2abd5adb4b39880892009b4507573668 294 Gene3D G3DSA:1.10.10.10 1 90 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00990 2abd5adb4b39880892009b4507573668 294 Pfam PF03466 LysR substrate binding domain 88 287 2.1E-26 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00990 2abd5adb4b39880892009b4507573668 294 SUPERFAMILY SSF46785 1 110 2.01E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15540 764180e6497cbe250d701d0fa973f33c 367 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 43 324 1.1E-58 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS15540 764180e6497cbe250d701d0fa973f33c 367 PIRSF PIRSF039026 1 357 7.0E-126 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS15540 764180e6497cbe250d701d0fa973f33c 367 Gene3D G3DSA:3.40.190.10 163 303 1.4E-4 T 28-03-2018 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 SMART SM00965 43 93 4.8E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 136 789 8.9E-110 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 Pfam PF07715 TonB-dependent Receptor Plug Domain 134 234 1.3E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 SUPERFAMILY SSF56935 96 790 2.98E-120 T 28-03-2018 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 Gene3D G3DSA:2.40.170.20 246 790 9.6E-76 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 Pfam PF00593 TonB dependent receptor 319 790 1.4E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS10925 840157f3b4252d5f9d5d3c569a5c6f4a 791 Gene3D G3DSA:2.170.130.10 93 245 3.3E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 SMART SM00861 362 545 4.7E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 SUPERFAMILY SSF52922 553 681 1.44E-44 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Gene3D G3DSA:3.40.50.970 1 369 1.5E-120 T 28-03-2018 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 SUPERFAMILY SSF52518 356 547 4.16E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 SUPERFAMILY SSF52518 9 335 2.59E-116 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 341 2.7E-156 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 680 2.8E-282 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Pfam PF02780 Transketolase, C-terminal domain 560 673 1.3E-13 T 28-03-2018 IPR033248 Transketolase, C-terminal domain AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Gene3D G3DSA:3.40.50.970 370 555 3.0E-39 T 28-03-2018 AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Pfam PF02779 Transketolase, pyrimidine binding domain 361 543 3.4E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFA_RS03385 044cab0d0906648938ff4e8792a38f32 681 Gene3D G3DSA:3.40.50.920 558 680 1.2E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 SUPERFAMILY SSF53323 710 922 1.31E-22 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 SUPERFAMILY SSF52518 422 604 2.8E-9 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 Gene3D G3DSA:3.40.920.10 709 921 6.0E-45 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 SUPERFAMILY SSF52518 20 248 9.42E-17 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 Gene3D G3DSA:3.40.50.970 244 621 2.9E-29 T 28-03-2018 AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 718 905 3.1E-23 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS15605 aa9d260b534ecf95f668e1c7541e71b2 1152 Gene3D G3DSA:3.40.50.970 2 228 9.1E-22 T 28-03-2018 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 Gene3D G3DSA:2.102.10.10 35 141 3.0E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 Gene3D G3DSA:3.90.380.10 142 417 3.7E-32 T 28-03-2018 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 SUPERFAMILY SSF50022 32 153 5.37E-33 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 103 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 SUPERFAMILY SSF55961 364 416 7.32E-24 T 28-03-2018 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 SUPERFAMILY SSF55961 144 327 7.32E-24 T 28-03-2018 AFA_RS00080 4a5bf8a1dd391f155fb103ec1905c1eb 501 Pfam PF00355 Rieske [2Fe-2S] domain 41 120 1.4E-14 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 225 1.0E-57 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 173 244 4.4E-20 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 Pfam PF00460 Flagella basal body rod protein 5 35 1.9E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 SUPERFAMILY SSF117143 79 206 2.35E-18 T 28-03-2018 AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 Gene3D G3DSA:2.60.120.10 6 117 4.2E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS05840 ea699e12117e349bd897de6e58796c89 249 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 122 1.7E-38 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SUPERFAMILY SSF56719 408 573 1.28E-84 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SUPERFAMILY SSF56719 743 808 1.28E-84 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SMART SM00387 39 186 3.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 518 535 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 123 137 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 434 448 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 500 516 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 538 550 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 43 58 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 78 91 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 282 295 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR00418 DNA topoisomerase II family signature 749 765 7.4E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 230 252 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 484 493 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 206 219 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 786 802 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 374 388 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 388 408 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 13 23 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 191 206 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 326 342 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 770 782 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 PRINTS PR01159 DNA gyrase subunit B signature 256 274 7.7E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Gene3D G3DSA:3.40.50.670 416 814 1.3E-103 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Gene3D G3DSA:3.30.565.10 4 234 8.8E-71 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SMART SM00433 43 810 3.5E-256 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Gene3D G3DSA:3.30.230.10 235 406 5.1E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Pfam PF01751 Toprim domain 433 544 3.0E-18 T 28-03-2018 IPR006171 TOPRIM domain AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 13 817 6.2E-293 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SUPERFAMILY SSF55874 13 225 9.95E-68 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Pfam PF00204 DNA gyrase B 231 404 5.1E-57 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 185 1.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 SUPERFAMILY SSF54211 231 406 1.9E-55 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 ProSitePatterns PS00177 DNA topoisomerase II signature. 436 444 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 10 817 97.272 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS00015 85ff4d8f44c56c5460db6c18c06adcb3 817 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 747 806 3.0E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFA_RS06365 917bb90ba17db9153e12108db84c4339 87 Gene3D G3DSA:1.20.5.1070 2 51 3.6E-6 T 28-03-2018 AFA_RS07645 6246d4cb05181e4cf9e43b4ef94fae26 455 Gene3D G3DSA:1.20.1250.20 249 455 9.5E-14 T 28-03-2018 AFA_RS07645 6246d4cb05181e4cf9e43b4ef94fae26 455 Gene3D G3DSA:1.20.1250.20 1 189 1.5E-23 T 28-03-2018 AFA_RS07645 6246d4cb05181e4cf9e43b4ef94fae26 455 SUPERFAMILY SSF103473 235 448 5.23E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS07645 6246d4cb05181e4cf9e43b4ef94fae26 455 SUPERFAMILY SSF103473 4 187 5.23E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS07645 6246d4cb05181e4cf9e43b4ef94fae26 455 Pfam PF07690 Major Facilitator Superfamily 8 401 5.8E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS06970 aa5ec87c8d4b0e71157d52590399cb3e 641 SUPERFAMILY SSF52266 430 639 1.21E-39 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain AFA_RS06970 aa5ec87c8d4b0e71157d52590399cb3e 641 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 438 629 4.1E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain AFA_RS06970 aa5ec87c8d4b0e71157d52590399cb3e 641 Gene3D G3DSA:3.40.50.1110 416 641 1.0E-29 T 28-03-2018 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 Pfam PF13307 Helicase C-terminal domain 583 746 4.6E-32 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SMART SM00491 597 734 3.3E-11 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 Gene3D G3DSA:3.40.50.300 182 551 8.0E-19 T 28-03-2018 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 Gene3D G3DSA:3.40.50.300 563 749 4.0E-8 T 28-03-2018 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SMART SM00488 175 412 3.8E-5 T 28-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 Pfam PF06733 DEAD_2 272 392 2.5E-17 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SUPERFAMILY SSF52540 512 526 2.73E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SUPERFAMILY SSF52540 326 392 2.73E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SUPERFAMILY SSF52540 553 728 2.73E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08385 c0dd32b83751dd210c027a158d52ab33 761 SUPERFAMILY SSF52540 201 252 2.73E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01190 8e728757303c325b66457ca7d4867f80 338 Gene3D G3DSA:3.40.50.2000 3 161 2.1E-36 T 28-03-2018 AFA_RS01190 8e728757303c325b66457ca7d4867f80 338 SUPERFAMILY SSF53756 4 318 3.45E-63 T 28-03-2018 AFA_RS01190 8e728757303c325b66457ca7d4867f80 338 Gene3D G3DSA:3.40.50.2000 165 323 8.1E-24 T 28-03-2018 AFA_RS01190 8e728757303c325b66457ca7d4867f80 338 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 4 316 2.0E-113 T 28-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 AFA_RS01190 8e728757303c325b66457ca7d4867f80 338 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 305 5.6E-56 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 Gene3D G3DSA:2.30.40.10 371 443 5.1E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 Pfam PF01979 Amidohydrolase family 57 432 5.3E-50 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 SUPERFAMILY SSF51556 59 385 1.47E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 SUPERFAMILY SSF51338 385 459 1.15E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 SUPERFAMILY SSF51338 6 59 1.15E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 Gene3D G3DSA:2.30.40.10 1 70 6.2E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS01640 d0579a16048130cd5d88b43db7dff4cf 502 Gene3D G3DSA:3.20.20.140 71 370 7.9E-51 T 28-03-2018 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 1.9E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 SUPERFAMILY SSF52833 2 107 7.5E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 PIRSF PIRSF000077 2 108 2.9E-43 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 PRINTS PR00421 Thioredoxin family signature 24 32 7.1E-10 T 28-03-2018 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 PRINTS PR00421 Thioredoxin family signature 72 83 7.1E-10 T 28-03-2018 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 PRINTS PR00421 Thioredoxin family signature 32 41 7.1E-10 T 28-03-2018 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 Pfam PF00085 Thioredoxin 5 105 2.4E-34 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 Gene3D G3DSA:3.40.30.10 1 108 5.1E-35 T 28-03-2018 AFA_RS11685 e31fdb7849b07b54a8ac8078798ef54a 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFA_RS05750 bd3dc6446b9a5adef9778ebed4b43534 166 Pfam PF01584 CheW-like domain 18 156 2.8E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05750 bd3dc6446b9a5adef9778ebed4b43534 166 Gene3D G3DSA:2.30.30.40 96 147 2.2E-14 T 28-03-2018 AFA_RS05750 bd3dc6446b9a5adef9778ebed4b43534 166 SUPERFAMILY SSF50341 17 158 1.26E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05750 bd3dc6446b9a5adef9778ebed4b43534 166 SMART SM00260 14 153 1.2E-43 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AFA_RS05750 bd3dc6446b9a5adef9778ebed4b43534 166 Gene3D G3DSA:2.40.50.180 37 95 1.9E-17 T 28-03-2018 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 320 408 2.4E-22 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 416 502 1.0E-24 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Gene3D G3DSA:3.40.50.1100 27 137 7.1E-31 T 28-03-2018 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 502 2.7E-244 T 28-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 SUPERFAMILY SSF53686 5 355 2.88E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Gene3D G3DSA:3.40.1020.10 328 502 1.6E-71 T 28-03-2018 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 SUPERFAMILY SSF55021 409 502 4.81E-28 T 28-03-2018 AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 1.1E-80 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS16250 8a7cb856b91712d8b294a1ea4008181f 502 Gene3D G3DSA:3.40.50.1100 138 317 9.3E-48 T 28-03-2018 AFA_RS03935 fcb5ea78059e76c5adbaa788fa0d0e3d 324 SUPERFAMILY SSF143631 11 306 2.18E-86 T 28-03-2018 IPR003374 ApbE-like domain AFA_RS03935 fcb5ea78059e76c5adbaa788fa0d0e3d 324 PIRSF PIRSF006268 1 316 2.0E-75 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFA_RS03935 fcb5ea78059e76c5adbaa788fa0d0e3d 324 Pfam PF02424 ApbE family 18 298 5.5E-72 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFA_RS03935 fcb5ea78059e76c5adbaa788fa0d0e3d 324 Gene3D G3DSA:3.10.520.10 9 312 8.4E-53 T 28-03-2018 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF01565 FAD binding domain 187 332 1.7E-22 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF13183 4Fe-4S dicluster domain 846 924 1.7E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF12447 Protein of unknown function (DUF3683) 21 137 7.1E-52 T 28-03-2018 IPR022153 Protein of unknown function DUF3683 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 910 921 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF11880 Domain of unknown function (DUF3400) 1269 1313 1.5E-24 T 28-03-2018 IPR021817 Protein of unknown function DUF3400 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 SUPERFAMILY SSF55103 686 812 1.14E-26 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 SUPERFAMILY SSF56176 148 418 9.0E-54 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF02754 Cysteine-rich domain 1180 1266 3.8E-4 T 28-03-2018 IPR004017 Cysteine-rich domain AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF02754 Cysteine-rich domain 1055 1144 2.0E-6 T 28-03-2018 IPR004017 Cysteine-rich domain AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF02913 FAD linked oxidases, C-terminal domain 697 809 7.1E-18 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Pfam PF02913 FAD linked oxidases, C-terminal domain 452 569 1.5E-5 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Gene3D G3DSA:3.30.43.10 133 240 2.6E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 SUPERFAMILY SSF55103 445 574 1.96E-15 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Gene3D G3DSA:3.30.465.10 252 440 8.8E-19 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 SUPERFAMILY SSF46548 843 939 3.5E-12 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFA_RS16260 b68a6ecde0e7c7b6da806ecde5edcb9e 1313 Gene3D G3DSA:1.10.1060.10 779 946 3.7E-13 T 28-03-2018 AFA_RS03200 dc707c090aa650316daa37aacf51eb35 540 Pfam PF00795 Carbon-nitrogen hydrolase 246 511 9.0E-29 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS03200 dc707c090aa650316daa37aacf51eb35 540 Gene3D G3DSA:3.60.110.10 227 507 1.0E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS03200 dc707c090aa650316daa37aacf51eb35 540 SUPERFAMILY SSF56317 240 518 4.19E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS03200 dc707c090aa650316daa37aacf51eb35 540 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 70 487 6.0E-91 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFA_RS03200 dc707c090aa650316daa37aacf51eb35 540 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 12 524 21.261 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 TIGRFAM TIGR01707 gspI: type II secretion system protein I 5 104 9.7E-15 T 28-03-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 25 3.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 Gene3D G3DSA:3.30.1300.30 32 117 2.9E-10 T 28-03-2018 AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 Pfam PF02501 Type II secretion system (T2SS), protein I 39 112 2.8E-10 T 28-03-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 2.3E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14280 e6f4fe385d241f0245969b43af2670a5 119 SUPERFAMILY SSF54523 38 112 6.28E-8 T 28-03-2018 AFA_RS09080 0595a26e0d354697e42f7d32f1fda653 329 PIRSF PIRSF017082 1 327 3.2E-61 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS09080 0595a26e0d354697e42f7d32f1fda653 329 Gene3D G3DSA:3.40.190.10 135 304 1.2E-8 T 28-03-2018 AFA_RS09080 0595a26e0d354697e42f7d32f1fda653 329 SUPERFAMILY SSF53850 87 293 5.7E-8 T 28-03-2018 AFA_RS09080 0595a26e0d354697e42f7d32f1fda653 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 2.0E-58 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 SUPERFAMILY SSF56112 6 315 2.04E-73 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 Gene3D G3DSA:3.30.200.20 1 102 4.0E-24 T 28-03-2018 AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 Hamap MF_00301 Homoserine kinase [thrB]. 1 323 148.456 T 28-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 Pfam PF01636 Phosphotransferase enzyme family 27 261 2.2E-28 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 3.7E-97 T 28-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFA_RS10865 51ae7cf4dbdb6ab37b59ae670f8f9a69 323 Gene3D G3DSA:3.90.1200.10 106 318 4.9E-23 T 28-03-2018 AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 Pfam PF00005 ABC transporter 37 188 7.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 21 263 2.9E-117 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 258 1.8E-4 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 SUPERFAMILY SSF52540 21 258 4.31E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 SMART SM00382 45 261 2.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 Gene3D G3DSA:3.40.50.300 3 261 1.0E-59 T 28-03-2018 AFA_RS16345 ca3bb1732c99ee51ca596b4b97a1e877 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 Gene3D G3DSA:3.40.190.10 88 173 4.1E-14 T 28-03-2018 AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 SUPERFAMILY SSF46785 3 111 1.77E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 Pfam PF03466 LysR substrate binding domain 88 290 8.6E-41 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 Gene3D G3DSA:3.40.190.10 174 258 1.5E-19 T 28-03-2018 AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 SUPERFAMILY SSF53850 88 291 1.99E-41 T 28-03-2018 AFA_RS08100 588d5895515dbfefd160d21d4251f712 293 Gene3D G3DSA:1.10.10.10 3 84 6.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 Pfam PF00072 Response regulator receiver domain 14 123 2.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 4.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 4.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 4.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 SUPERFAMILY SSF46894 144 205 2.0E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.6E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 SUPERFAMILY SSF52172 15 164 5.27E-31 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 Gene3D G3DSA:3.40.50.2300 9 123 6.0E-25 T 28-03-2018 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 SMART SM00448 12 123 9.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 SMART SM00421 147 204 5.8E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10820 5024b32c059b05d856dfc4c6f9f15435 212 Gene3D G3DSA:1.10.10.10 124 209 6.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.068 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 SMART SM01374 1 122 2.6E-82 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 Gene3D G3DSA:2.40.150.20 1 122 8.7E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 SUPERFAMILY SSF50193 1 122 2.62E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.6E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18050 8a2c4f96a52fc07c7bfd0ee25fb935ae 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.0E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 AFA_RS00660 1a98b0edc44c6cb5f8c8ae1054128ef0 152 Hamap MF_00598 Protein Smg [smg]. 1 152 25.458 T 28-03-2018 IPR007456 Smg AFA_RS00660 1a98b0edc44c6cb5f8c8ae1054128ef0 152 Pfam PF04361 Protein of unknown function (DUF494) 1 152 9.7E-52 T 28-03-2018 IPR007456 Smg AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 SUPERFAMILY SSF56672 38 232 1.67E-6 T 28-03-2018 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 153 166 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 245 251 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 54 66 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 186 197 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 89 103 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 105 123 1.2E-16 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 46 236 3.5E-14 T 28-03-2018 IPR000477 Reverse transcriptase domain AFA_RS12345 64f342f87bbee5f2cf83ea3fc1e024fd 389 Gene3D G3DSA:3.30.70.270 72 250 6.2E-12 T 28-03-2018 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 Gene3D G3DSA:3.40.190.10 92 181 2.6E-13 T 28-03-2018 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 Gene3D G3DSA:1.10.10.10 1 82 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 Pfam PF03466 LysR substrate binding domain 92 294 6.2E-22 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 Gene3D G3DSA:3.40.190.10 182 269 4.4E-9 T 28-03-2018 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 SUPERFAMILY SSF46785 1 83 3.76E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17345 52bea59baf9343ec29f00955a33841f8 321 SUPERFAMILY SSF53850 92 298 3.62E-22 T 28-03-2018 AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 Pfam PF07883 Cupin domain 117 179 5.9E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 SUPERFAMILY SSF51182 76 179 6.4E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 Gene3D G3DSA:1.10.260.40 1 61 6.6E-13 T 28-03-2018 AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 SMART SM00530 4 59 4.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 Pfam PF13560 Helix-turn-helix domain 2 57 1.0E-9 T 28-03-2018 AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 Gene3D G3DSA:2.60.120.10 62 183 7.6E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS18500 0d55741dfc4316dc0c8ec2e71bc3a827 183 SUPERFAMILY SSF47413 2 64 7.32E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 SMART SM00382 337 533 3.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 SMART SM00382 47 246 4.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 282 9.7E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 SUPERFAMILY SSF52540 303 554 9.5E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 Pfam PF00005 ABC transporter 329 484 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 Pfam PF00005 ABC transporter 39 196 4.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 Gene3D G3DSA:3.40.50.300 15 300 1.2E-63 T 28-03-2018 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 Gene3D G3DSA:3.40.50.300 301 561 8.9E-71 T 28-03-2018 AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 SUPERFAMILY SSF52540 19 267 2.11E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04740 7b8df8bf5a45136563909f899eb875a4 561 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 Pfam PF01061 ABC-2 type transporter 5 216 8.6E-35 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 8.4E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 8.4E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 8.4E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 8.4E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 21 42 8.4E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS10650 f8ea48cde5125a5d80767fcd3999252c 253 PIRSF PIRSF006648 10 252 6.6E-31 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 SUPERFAMILY SSF82829 263 339 6.28E-15 T 28-03-2018 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 31 219 1.6E-42 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 SUPERFAMILY SSF52402 20 249 1.28E-48 T 28-03-2018 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 Pfam PF01171 PP-loop family 31 216 2.3E-45 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 Pfam PF09179 TilS substrate binding domain 268 336 1.0E-10 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 19 329 20.115 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFA_RS04565 16cdaff6d9e896d140cd63aa731bd934 357 Gene3D G3DSA:3.40.50.620 23 244 1.3E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS15530 f1e6bcda36c5822f89b0708e49cda330 130 Gene3D G3DSA:3.30.230.10 3 130 1.6E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS15530 f1e6bcda36c5822f89b0708e49cda330 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.281 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid AFA_RS15530 f1e6bcda36c5822f89b0708e49cda330 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 7.0E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AFA_RS15530 f1e6bcda36c5822f89b0708e49cda330 130 SUPERFAMILY SSF54211 5 130 8.34E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS15530 f1e6bcda36c5822f89b0708e49cda330 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 Gene3D G3DSA:3.30.190.20 150 228 3.4E-18 T 28-03-2018 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 7.0E-104 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 5.4E-51 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.774 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 SUPERFAMILY SSF56808 6 225 3.92E-81 T 28-03-2018 IPR023674 Ribosomal protein L1-like AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 PIRSF PIRSF002155 1 227 4.6E-77 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18360 aac950834bb25b59af3d57b152347a04 231 Gene3D G3DSA:3.40.50.790 68 149 4.7E-36 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 SUPERFAMILY SSF54862 4 71 2.24E-18 T 28-03-2018 AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 Pfam PF00037 4Fe-4S binding domain 5 25 3.4E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 Gene3D G3DSA:3.30.70.20 50 79 0.064 T 28-03-2018 AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 Gene3D G3DSA:3.30.70.20 1 20 5.6E-4 T 28-03-2018 AFA_RS14905 99c7902123808b6af68562ab65b26fa5 85 Gene3D G3DSA:3.30.70.20 21 49 6.5E-8 T 28-03-2018 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 SUPERFAMILY SSF53850 31 333 4.83E-70 T 28-03-2018 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 Gene3D G3DSA:3.40.190.10 29 173 3.1E-19 T 28-03-2018 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 Gene3D G3DSA:3.40.190.10 174 335 3.2E-27 T 28-03-2018 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 Gene3D G3DSA:1.10.3720.10 343 640 3.4E-40 T 28-03-2018 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 323 7.1E-57 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 SUPERFAMILY SSF161098 443 627 1.83E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18280 b99844e0504cb80dc0dfdc1acfe6c84e 644 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 466 629 5.8E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 Gene3D G3DSA:1.10.760.10 49 200 1.3E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 Gene3D G3DSA:1.10.760.10 220 295 1.8E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 PRINTS PR00607 Class IE cytochrome C signature 282 293 5.0E-13 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 PRINTS PR00607 Class IE cytochrome C signature 240 250 5.0E-13 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 PRINTS PR00607 Class IE cytochrome C signature 268 280 5.0E-13 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 PRINTS PR00607 Class IE cytochrome C signature 229 240 5.0E-13 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 SUPERFAMILY SSF46626 86 162 3.1E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 SUPERFAMILY SSF46626 221 294 6.45E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 222 292 4.7E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01795 446a9264a2c76f8ad81f7e9498745cf4 297 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 85 160 3.1E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS16965 e13f6a31f6e60301b99bf3d24ffbf405 492 Pfam PF13641 Glycosyltransferase like family 2 59 288 4.6E-31 T 28-03-2018 AFA_RS16965 e13f6a31f6e60301b99bf3d24ffbf405 492 Gene3D G3DSA:3.90.550.10 29 324 2.8E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16965 e13f6a31f6e60301b99bf3d24ffbf405 492 SUPERFAMILY SSF53448 58 324 2.91E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS15510 4c85e293ecbc3cda59200d45c1222c1a 714 Gene3D G3DSA:3.40.50.300 426 662 1.9E-18 T 28-03-2018 AFA_RS15510 4c85e293ecbc3cda59200d45c1222c1a 714 Gene3D G3DSA:3.40.50.300 201 420 1.0E-17 T 28-03-2018 AFA_RS15510 4c85e293ecbc3cda59200d45c1222c1a 714 SUPERFAMILY SSF52540 207 456 3.07E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15510 4c85e293ecbc3cda59200d45c1222c1a 714 SUPERFAMILY SSF52540 518 640 3.07E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15510 4c85e293ecbc3cda59200d45c1222c1a 714 Pfam PF13538 UvrD-like helicase C-terminal domain 587 634 2.3E-10 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 263 5.1E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 247 5.1E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 Gene3D G3DSA:1.10.10.60 151 223 5.9E-13 T 28-03-2018 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 Pfam PF12833 Helix-turn-helix domain 187 263 3.9E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 SUPERFAMILY SSF46689 174 214 4.3E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 Pfam PF02311 AraC-like ligand binding domain 14 102 5.1E-13 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 SUPERFAMILY SSF46689 218 263 5.38E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 SUPERFAMILY SSF51215 21 104 1.96E-12 T 28-03-2018 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 Gene3D G3DSA:2.60.120.10 16 104 1.2E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 218 259 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 Gene3D G3DSA:1.10.10.60 224 264 9.4E-15 T 28-03-2018 AFA_RS18325 e7c5e92ecab772df96651156004584e5 264 SMART SM00342 181 263 4.5E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS00290 6142b7166a36ed20894c3871aca0c72d 262 SUPERFAMILY SSF102198 18 260 2.09E-54 T 28-03-2018 AFA_RS00290 6142b7166a36ed20894c3871aca0c72d 262 Pfam PF04199 Putative cyclase 22 199 3.6E-35 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFA_RS00290 6142b7166a36ed20894c3871aca0c72d 262 Gene3D G3DSA:3.50.30.50 16 262 8.2E-55 T 28-03-2018 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 Gene3D G3DSA:1.20.1260.10 1 153 1.1E-35 T 28-03-2018 IPR012347 Ferritin-related AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 3.7E-42 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PIRSF PIRSF002560 1 154 2.1E-58 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 85 105 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 106 126 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 23 43 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 44 64 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 3 22 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 PRINTS PR00601 Bacterioferritin signature 128 149 1.2E-38 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 Pfam PF00210 Ferritin-like domain 9 143 1.0E-34 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFA_RS07390 f816a92cc2b924c790a5aebf8f3d172b 154 SUPERFAMILY SSF47240 1 154 2.71E-43 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Gene3D G3DSA:3.90.199.10 40 293 1.6E-106 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 570 598 1.1 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 673 709 2.7E-5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 10 765 32.238 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Gene3D G3DSA:1.10.268.10 372 511 3.8E-42 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 SUPERFAMILY SSF56719 37 511 5.89E-145 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 SUPERFAMILY SSF101904 526 758 4.32E-43 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 16 757 8.7E-226 T 28-03-2018 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 38 495 2.4E-126 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 Gene3D G3DSA:2.120.10.90 519 760 9.5E-40 T 28-03-2018 AFA_RS11675 b507d60eaf9b28a2fe4a2cef994173ae 769 SMART SM00434 17 489 1.4E-208 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 SUPERFAMILY SSF89796 57 268 1.22E-20 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 Pfam PF02515 CoA-transferase family III 284 522 7.2E-52 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 Pfam PF02515 CoA-transferase family III 66 256 3.9E-8 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 Gene3D G3DSA:3.40.50.10540 278 574 8.4E-63 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 Gene3D G3DSA:3.40.50.10540 44 270 6.8E-14 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS08175 1ab66d0861dd99bb16f6111f847562d1 591 SUPERFAMILY SSF89796 282 573 6.41E-63 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.4E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 Gene3D G3DSA:1.10.10.10 3 90 9.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 Pfam PF03466 LysR substrate binding domain 90 291 1.7E-44 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 SUPERFAMILY SSF53850 90 295 7.91E-46 T 28-03-2018 AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 SUPERFAMILY SSF46785 5 85 1.26E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 Gene3D G3DSA:3.40.190.10 175 264 9.6E-27 T 28-03-2018 AFA_RS02670 a0095f866faad76ecac9f840a034e95d 305 Gene3D G3DSA:3.40.190.10 91 174 3.1E-9 T 28-03-2018 AFA_RS04045 8b79d8a2cd7a84b835d3a1d9d1aaa074 164 Gene3D G3DSA:3.90.960.10 1 160 8.8E-36 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS04045 8b79d8a2cd7a84b835d3a1d9d1aaa074 164 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 154 3.2E-46 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFA_RS04045 8b79d8a2cd7a84b835d3a1d9d1aaa074 164 SUPERFAMILY SSF55826 10 157 1.44E-40 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS04045 8b79d8a2cd7a84b835d3a1d9d1aaa074 164 PIRSF PIRSF006181 5 161 9.5E-46 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFA_RS04045 8b79d8a2cd7a84b835d3a1d9d1aaa074 164 Pfam PF04073 Aminoacyl-tRNA editing domain 36 149 6.7E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 Gene3D G3DSA:3.40.50.1240 1 248 2.2E-70 T 28-03-2018 IPR029033 Histidine phosphatase superfamily AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 PIRSF PIRSF000709 134 239 0.2 T 28-03-2018 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 PIRSF PIRSF000709 3 111 6.4E-9 T 28-03-2018 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 246 4.1E-117 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 SUPERFAMILY SSF53254 1 245 4.34E-80 T 28-03-2018 IPR029033 Histidine phosphatase superfamily AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.227 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 121 3.0E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 219 8.1E-8 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFA_RS16425 6cca91585079e268fd83e057049bc01c 248 SMART SM00855 3 189 1.1E-28 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 SMART SM00257 66 110 2.0E-15 T 28-03-2018 IPR018392 LysM domain AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 Pfam PF01476 LysM domain 67 109 1.8E-13 T 28-03-2018 IPR018392 LysM domain AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 Gene3D G3DSA:3.10.350.10 60 113 2.7E-17 T 28-03-2018 AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 Pfam PF01551 Peptidase family M23 174 267 2.7E-28 T 28-03-2018 IPR016047 Peptidase M23 AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 Gene3D G3DSA:2.70.70.10 114 274 2.5E-35 T 28-03-2018 AFA_RS10580 2b3036237ca167162c56c770bc2d7789 274 SUPERFAMILY SSF51261 67 271 3.09E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 Pfam PF00756 Putative esterase 287 508 1.2E-31 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 SUPERFAMILY SSF81296 139 264 8.96E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 Pfam PF11806 Domain of unknown function (DUF3327) 164 266 8.4E-14 T 28-03-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 SUPERFAMILY SSF53474 270 513 6.68E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 Gene3D G3DSA:2.60.40.10 135 251 5.1E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 Gene3D G3DSA:3.40.50.1820 259 516 2.9E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01410 8f3a97fab1bcfd1ab93daf9c82867758 525 Gene3D G3DSA:2.60.120.380 39 116 0.0016 T 28-03-2018 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 Gene3D G3DSA:3.30.70.920 56 153 5.6E-19 T 28-03-2018 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 SUPERFAMILY SSF54909 66 147 1.23E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 Gene3D G3DSA:1.10.10.10 3 54 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 SMART SM00344 3 112 5.5E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 SUPERFAMILY SSF46785 2 63 4.23E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.2E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 4.8E-19 T 28-03-2018 AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 Pfam PF01037 Lrp/AsnC ligand binding domain 77 142 5.5E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS02240 335f5662697e552e443f5dfdd34aab02 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 39.226 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 4 15 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 194 208 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 85 102 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 156 173 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 173 184 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 4 22 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 PRINTS PR00395 Ribosomal protein S2 signature 35 44 1.2E-35 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 Pfam PF00318 Ribosomal protein S2 7 222 1.1E-91 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 Gene3D G3DSA:3.40.50.10490 3 249 4.3E-89 T 28-03-2018 AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 SUPERFAMILY SSF52313 4 235 2.75E-91 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain AFA_RS10210 1240e597c41abe2e2e3a7eeb9ae9f44e 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 3.4E-98 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS04210 15d1dbeeeeaf1e1d0be49b1c3b6bdd3b 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 284 8.4E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04210 15d1dbeeeeaf1e1d0be49b1c3b6bdd3b 287 SUPERFAMILY SSF161098 33 280 2.62E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04210 15d1dbeeeeaf1e1d0be49b1c3b6bdd3b 287 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 23 285 1.2E-85 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFA_RS04210 15d1dbeeeeaf1e1d0be49b1c3b6bdd3b 287 Gene3D G3DSA:1.10.3720.10 14 282 3.3E-38 T 28-03-2018 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SUPERFAMILY SSF55874 841 1007 6.68E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Gene3D G3DSA:3.30.450.20 637 790 1.4E-20 T 28-03-2018 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SMART SM00448 1030 1140 8.4E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 896 1005 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SUPERFAMILY SSF52172 1028 1145 1.34E-17 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Pfam PF12860 PAS fold 643 759 8.6E-40 T 28-03-2018 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Gene3D G3DSA:3.30.565.10 846 1006 2.0E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Pfam PF00512 His Kinase A (phospho-acceptor) domain 786 851 9.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Gene3D G3DSA:1.10.287.130 791 845 3.2E-9 T 28-03-2018 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SUPERFAMILY SSF55785 649 764 3.59E-9 T 28-03-2018 IPR000014 PAS domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Gene3D G3DSA:3.40.50.2300 1026 1146 5.4E-17 T 28-03-2018 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SMART SM00091 637 704 6.2E-4 T 28-03-2018 IPR000014 PAS domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 984 8.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 931 945 8.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 990 1003 8.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SMART SM00387 895 1006 4.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 Pfam PF00072 Response regulator receiver domain 1032 1138 9.5E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SUPERFAMILY SSF47384 771 851 1.12E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS12425 801ea4395b1ead73bb2151909f7d39fb 1147 SMART SM00388 786 851 2.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15415 e4d2855957a21cd4533c0f62136224be 238 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 7 224 3.5E-122 T 28-03-2018 IPR014063 Arsenate resistance ArsH AFA_RS15415 e4d2855957a21cd4533c0f62136224be 238 Gene3D G3DSA:3.40.50.360 24 223 1.8E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS15415 e4d2855957a21cd4533c0f62136224be 238 Pfam PF03358 NADPH-dependent FMN reductase 32 175 2.5E-29 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS15415 e4d2855957a21cd4533c0f62136224be 238 SUPERFAMILY SSF52218 25 225 1.09E-64 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS07240 6d5a8fed55daf8847667f24e2b13e1f5 129 PIRSF PIRSF016789 2 123 1.6E-41 T 28-03-2018 IPR007401 Protein of unknown function DUF454 AFA_RS07240 6d5a8fed55daf8847667f24e2b13e1f5 129 Pfam PF04304 Protein of unknown function (DUF454) 3 118 6.3E-41 T 28-03-2018 IPR007401 Protein of unknown function DUF454 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 Gene3D G3DSA:3.30.70.20 1 94 7.2E-11 T 28-03-2018 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 Pfam PF14697 4Fe-4S dicluster domain 78 132 6.8E-16 T 28-03-2018 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 Gene3D G3DSA:3.30.70.20 95 116 1.3E-9 T 28-03-2018 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 115 126 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 Pfam PF04060 Putative Fe-S cluster 13 45 6.5E-11 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 SUPERFAMILY SSF54862 8 138 2.25E-27 T 28-03-2018 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 Gene3D G3DSA:3.30.70.20 117 191 1.3E-7 T 28-03-2018 AFA_RS13220 1dce50c512553b359cc844bdfd6074bd 213 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 141 2.4E-62 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:3.90.1100.10 436 650 2.3E-81 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:3.90.1100.10 651 719 7.8E-16 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 361 460 1.7E-15 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 227 5.2E-7 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.2E-31 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 SUPERFAMILY SSF64484 348 945 0.0 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 SUPERFAMILY SSF64484 1058 1368 0.0 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 SUPERFAMILY SSF64484 12 230 0.0 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.241 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF04563 RNA polymerase beta subunit 26 506 5.7E-39 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:3.90.1800.10 1295 1338 9.1E-12 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:2.40.50.100 721 801 6.0E-27 T 28-03-2018 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1292 3.9E-155 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 1.1E-25 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:2.40.50.150 835 1064 1.2E-51 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:2.40.270.10 1065 1270 3.5E-78 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Gene3D G3DSA:3.90.1110.10 152 435 9.3E-64 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1366 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18345 a3f3e8ce5ae1646ba2f1c4926f545ada 1370 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 2.4E-24 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS01050 b922230c811e6eca0cc258c7eed1bc80 237 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 124 2.4E-16 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS01050 b922230c811e6eca0cc258c7eed1bc80 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 222 4.7E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01050 b922230c811e6eca0cc258c7eed1bc80 237 SUPERFAMILY SSF161098 16 214 6.41E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01050 b922230c811e6eca0cc258c7eed1bc80 237 Gene3D G3DSA:1.10.3720.10 3 235 1.5E-36 T 28-03-2018 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 176 196 5.2E-9 T 28-03-2018 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 138 155 5.2E-9 T 28-03-2018 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 156 175 5.2E-9 T 28-03-2018 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01021 OMPA domain signature 93 115 2.9E-22 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01021 OMPA domain signature 123 138 2.9E-22 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 PRINTS PR01021 OMPA domain signature 138 154 2.9E-22 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 Gene3D G3DSA:3.30.1330.60 68 198 8.8E-46 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 SUPERFAMILY SSF103088 68 193 6.41E-41 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS11995 558fb1853dc16f8ac825803634ef37ab 198 Pfam PF00691 OmpA family 92 187 7.8E-27 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS05805 af810f7737db689bc0eb3e67d571dd5f 149 Gene3D G3DSA:1.20.58.300 1 123 3.3E-12 T 28-03-2018 AFA_RS05805 af810f7737db689bc0eb3e67d571dd5f 149 Pfam PF05130 FlgN protein 2 139 3.4E-16 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 AFA_RS05805 af810f7737db689bc0eb3e67d571dd5f 149 SUPERFAMILY SSF140566 3 122 7.59E-11 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 SUPERFAMILY SSF47203 257 386 4.76E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 Gene3D G3DSA:1.10.540.10 14 127 1.3E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 SUPERFAMILY SSF56645 25 226 1.23E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 PIRSF PIRSF016578 12 410 6.6E-93 T 28-03-2018 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 Gene3D G3DSA:2.40.110.10 132 217 2.4E-17 T 28-03-2018 AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 257 388 5.7E-24 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFA_RS13595 b8d49d923aa93587f9c3325e2ccdc621 411 Gene3D G3DSA:1.20.140.10 218 387 1.0E-12 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:3.40.50.300 68 188 8.5E-29 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:3.40.50.300 2 67 2.4E-10 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:3.30.70.240 402 482 1.3E-19 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Pfam PF00679 Elongation factor G C-terminus 397 478 9.4E-23 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 SUPERFAMILY SSF54980 399 514 6.23E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:2.40.50.250 484 574 5.5E-38 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Pfam PF00009 Elongation factor Tu GTP binding domain 5 195 2.5E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:3.30.70.870 303 401 2.4E-32 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 134 1.4E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 600 2.3E-284 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 SUPERFAMILY SSF54980 303 388 2.88E-13 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 SUPERFAMILY SSF50447 151 300 5.18E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 6.9E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 6.9E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 6.9E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 6.9E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 6.9E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Pfam PF03144 Elongation factor Tu domain 2 219 290 2.9E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 SMART SM00838 396 484 0.0093 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 Gene3D G3DSA:2.40.30.10 189 301 1.2E-18 T 28-03-2018 AFA_RS05115 5aec93e9d1481257d7dbf4e06b850b72 605 SUPERFAMILY SSF52540 4 206 1.14E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 2.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 SUPERFAMILY SSF55920 1 252 1.96E-80 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 Gene3D G3DSA:3.90.230.10 1 254 1.8E-74 T 28-03-2018 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 Pfam PF00557 Metallopeptidase family M24 10 239 2.7E-47 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 Hamap MF_01974 Methionine aminopeptidase [map]. 1 248 35.184 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS03230 4d87ef1130d2c3c9b288f8d955965aa1 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.6E-83 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 Pfam PF01546 Peptidase family M20/M25/M40 83 409 9.6E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 SUPERFAMILY SSF53187 339 412 5.14E-94 T 28-03-2018 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 SUPERFAMILY SSF53187 3 226 5.14E-94 T 28-03-2018 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 Gene3D G3DSA:3.40.630.10 6 261 3.4E-43 T 28-03-2018 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 Gene3D G3DSA:3.40.630.10 262 414 3.8E-26 T 28-03-2018 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 SUPERFAMILY SSF55031 216 331 1.47E-25 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 PIRSF PIRSF001235 9 414 5.0E-132 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 14 410 3.8E-130 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AFA_RS08900 7034ca1a1bbf28462bfa36fa33037b10 414 Pfam PF07687 Peptidase dimerisation domain 213 315 5.3E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 3 427 7.5E-116 T 28-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 Gene3D G3DSA:3.40.50.720 1 48 1.6E-7 T 28-03-2018 AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 Gene3D G3DSA:3.90.660.20 49 373 5.3E-25 T 28-03-2018 AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 Pfam PF01593 Flavin containing amine oxidoreductase 11 426 1.5E-34 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 SUPERFAMILY SSF51905 1 295 7.77E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05270 25c4fe7919470ec651c08b3edbf9c3b9 428 SUPERFAMILY SSF51905 390 427 7.77E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02880 6c631deb405078ac295b64881a4e053e 178 Pfam PF04115 Ureidoglycolate lyase 6 136 2.2E-14 T 28-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFA_RS02880 6c631deb405078ac295b64881a4e053e 178 SUPERFAMILY SSF51182 6 165 2.57E-28 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS02880 6c631deb405078ac295b64881a4e053e 178 Gene3D G3DSA:2.60.120.480 5 172 6.3E-24 T 28-03-2018 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFA_RS12390 253335b1222daeb5d070f87001dd85ee 210 PIRSF PIRSF006324 1 206 6.0E-45 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS12390 253335b1222daeb5d070f87001dd85ee 210 Pfam PF01810 LysE type translocator 15 203 9.9E-31 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 Gene3D G3DSA:1.10.10.60 274 324 3.1E-14 T 28-03-2018 AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 SUPERFAMILY SSF46689 272 321 5.82E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 SMART SM00342 237 319 5.9E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 Pfam PF12833 Helix-turn-helix domain 245 320 4.7E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 18 189 1.1E-26 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AFA_RS11030 d7fcbaaa689c7a27724f48029df74876 326 Gene3D G3DSA:1.10.10.60 201 273 8.9E-4 T 28-03-2018 AFA_RS00570 d2555ef44660d01cb0cfd0a41c24aed4 217 Gene3D G3DSA:1.10.3720.10 5 217 5.4E-37 T 28-03-2018 AFA_RS00570 d2555ef44660d01cb0cfd0a41c24aed4 217 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 206 9.8E-56 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 AFA_RS00570 d2555ef44660d01cb0cfd0a41c24aed4 217 SUPERFAMILY SSF161098 7 213 5.76E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00570 d2555ef44660d01cb0cfd0a41c24aed4 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 206 3.9E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 Gene3D G3DSA:3.40.50.1000 1 32 0.3 T 28-03-2018 IPR023214 HAD-like domain AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 SUPERFAMILY SSF56784 3 218 7.97E-47 T 28-03-2018 IPR023214 HAD-like domain AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 55 186 2.7E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 Gene3D G3DSA:3.40.50.1000 75 225 8.9E-23 T 28-03-2018 IPR023214 HAD-like domain AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 6.5E-22 T 28-03-2018 IPR023214 HAD-like domain AFA_RS00940 6ab6ef475cb062b769cd80c9ab0db618 226 Gene3D G3DSA:1.10.150.240 33 74 8.2E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 11 219 9.3E-54 T 28-03-2018 IPR010016 KipI family AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 Gene3D G3DSA:2.40.100.10 95 228 1.4E-47 T 28-03-2018 IPR029000 Cyclophilin-like domain AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 Gene3D G3DSA:3.30.1360.40 2 88 5.2E-14 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 8 210 3.0E-63 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 SUPERFAMILY SSF160467 10 101 2.62E-12 T 28-03-2018 AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 SMART SM00796 5 210 2.7E-78 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFA_RS16240 1f6014d5ea5c146f03dd64aa28b54339 232 SUPERFAMILY SSF50891 96 226 1.44E-44 T 28-03-2018 IPR029000 Cyclophilin-like domain AFA_RS15155 55d441b286b29f2c2df0b16a065f51f2 359 SUPERFAMILY SSF53807 53 354 4.71E-36 T 28-03-2018 AFA_RS15155 55d441b286b29f2c2df0b16a065f51f2 359 Gene3D G3DSA:3.40.50.1980 167 331 4.1E-23 T 28-03-2018 AFA_RS15155 55d441b286b29f2c2df0b16a065f51f2 359 Gene3D G3DSA:3.40.50.1980 50 166 2.8E-11 T 28-03-2018 AFA_RS15155 55d441b286b29f2c2df0b16a065f51f2 359 Pfam PF01497 Periplasmic binding protein 102 287 3.5E-15 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 SMART SM00155 184 211 0.0029 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 SMART SM00155 424 451 1.4E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 SUPERFAMILY SSF56024 278 513 2.06E-29 T 28-03-2018 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 SUPERFAMILY SSF56024 64 255 3.45E-41 T 28-03-2018 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 Gene3D G3DSA:3.30.870.10 324 514 8.6E-23 T 28-03-2018 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 Gene3D G3DSA:3.30.870.10 86 289 3.3E-28 T 28-03-2018 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 Pfam PF13091 PLD-like domain 100 243 1.3E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS15050 b3598af09f69583c54857d6b8201ac1c 534 Pfam PF13091 PLD-like domain 333 477 1.6E-21 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 525 569 4.1E-6 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 Gene3D G3DSA:1.20.1170.10 76 567 2.0E-5 T 28-03-2018 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 SUPERFAMILY SSF64518 140 569 6.02E-26 T 28-03-2018 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 Pfam PF00460 Flagella basal body rod protein 7 33 7.3E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 335 3.9E-78 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 263 285 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 463 482 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 536 560 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 489 510 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 48 70 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS05865 117d9efd2435b643d7a30fe0cf8d5a66 571 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 2.1E-33 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFA_RS10760 3e50da9c5984b5028169baf35a3e076e 271 Gene3D G3DSA:3.40.30.10 131 271 4.4E-22 T 28-03-2018 AFA_RS10760 3e50da9c5984b5028169baf35a3e076e 271 SUPERFAMILY SSF52833 152 270 1.91E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10760 3e50da9c5984b5028169baf35a3e076e 271 Pfam PF00578 AhpC/TSA family 153 251 8.6E-11 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS10760 3e50da9c5984b5028169baf35a3e076e 271 ProSitePatterns PS00194 Thioredoxin family active site. 165 183 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFA_RS10760 3e50da9c5984b5028169baf35a3e076e 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 5 117 2.7E-6 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AFA_RS09620 6a52aae252c41e6fe4a24763ba022432 159 Pfam PF07511 Protein of unknown function (DUF1525) 46 158 2.0E-23 T 28-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 AFA_RS09620 6a52aae252c41e6fe4a24763ba022432 159 Gene3D G3DSA:3.40.30.10 11 159 6.7E-4 T 28-03-2018 AFA_RS09620 6a52aae252c41e6fe4a24763ba022432 159 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 46 157 8.4E-22 T 28-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 AFA_RS08755 f14bfef6d3f419cefdb5c98db1678e20 557 Pfam PF04542 Sigma-70 region 2 26 93 2.5E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS08755 f14bfef6d3f419cefdb5c98db1678e20 557 SUPERFAMILY SSF88946 11 93 1.06E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS08755 f14bfef6d3f419cefdb5c98db1678e20 557 Pfam PF10099 Anti-sigma-K factor rskA 330 532 1.8E-15 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 AFA_RS08755 f14bfef6d3f419cefdb5c98db1678e20 557 Gene3D G3DSA:1.10.1740.10 10 96 6.6E-13 T 28-03-2018 AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 9.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 Pfam PF00106 short chain dehydrogenase 4 196 5.2E-62 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.1E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.1E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.1E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04990 67305a871559285548389cd8fed094ee 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 1.4E-115 T 28-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 AFA_RS04990 67305a871559285548389cd8fed094ee 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 0.0053 T 28-03-2018 AFA_RS04990 67305a871559285548389cd8fed094ee 245 SUPERFAMILY SSF51735 3 244 4.98E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04990 67305a871559285548389cd8fed094ee 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS04990 67305a871559285548389cd8fed094ee 245 Gene3D G3DSA:3.40.50.720 3 245 2.1E-68 T 28-03-2018 AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 SUPERFAMILY SSF52172 1 182 1.76E-36 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 2.7E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 SMART SM00448 4 114 9.0E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 Gene3D G3DSA:3.40.50.2300 3 126 3.3E-31 T 28-03-2018 AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 Gene3D G3DSA:1.10.10.10 127 235 8.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 Pfam PF00072 Response regulator receiver domain 6 115 1.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS07315 57fd21f5bef8956ef243cfdec3a49106 235 SMART SM00862 152 228 6.1E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Pfam PF01926 50S ribosome-binding GTPase 5 121 9.7E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.3E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.3E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.3E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.3E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 SUPERFAMILY SSF52540 3 301 2.03E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Gene3D G3DSA:1.10.150.300 110 200 2.6E-28 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 4.6E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 4.0E-159 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Gene3D G3DSA:3.10.20.30 263 362 1.5E-45 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 SUPERFAMILY SSF81271 279 359 2.62E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.43 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 PIRSF PIRSF006641 1 363 2.9E-153 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFA_RS02830 a4aafde1600f0ed2f164125b38250ccf 363 Gene3D G3DSA:3.40.50.300 1 79 2.6E-8 T 28-03-2018 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 5 560 2.9E-293 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 Gene3D G3DSA:3.40.1080.10 234 541 2.4E-40 T 28-03-2018 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 Gene3D G3DSA:3.40.1080.10 2 223 6.9E-35 T 28-03-2018 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 6 560 6.9E-286 T 28-03-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 SUPERFAMILY SSF100950 44 282 9.21E-32 T 28-03-2018 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 SUPERFAMILY SSF100950 230 389 7.18E-22 T 28-03-2018 AFA_RS04495 ee08ea3172307aa41a4d66be86e109fc 560 SUPERFAMILY SSF100950 421 486 7.18E-22 T 28-03-2018 AFA_RS14665 86f57339f4ca75bd7f5c3b4efb5aced1 359 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 30 290 6.5E-53 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AFA_RS14665 86f57339f4ca75bd7f5c3b4efb5aced1 359 Gene3D G3DSA:3.40.50.2300 27 144 1.9E-30 T 28-03-2018 AFA_RS14665 86f57339f4ca75bd7f5c3b4efb5aced1 359 Gene3D G3DSA:3.40.50.2300 145 358 5.3E-49 T 28-03-2018 AFA_RS18540 d3e3a9dbba218451fd35d97fcc55cf9a 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 4.6E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS18540 d3e3a9dbba218451fd35d97fcc55cf9a 252 SMART SM00382 26 227 1.9E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS18540 d3e3a9dbba218451fd35d97fcc55cf9a 252 Pfam PF00005 ABC transporter 18 177 1.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18540 d3e3a9dbba218451fd35d97fcc55cf9a 252 SUPERFAMILY SSF52540 2 249 1.95E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18540 d3e3a9dbba218451fd35d97fcc55cf9a 252 Gene3D G3DSA:3.40.50.300 1 252 8.4E-53 T 28-03-2018 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 PIRSF PIRSF005917 18 311 3.0E-89 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 31 306 5.6E-71 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 108 119 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 31 233 1.2E-26 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 30 254 33.382 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 Gene3D G3DSA:3.40.1010.10 28 138 1.2E-36 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 SUPERFAMILY SSF53790 30 252 3.14E-71 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS16375 3f5548d26577df3567fb1116e849058e 312 Gene3D G3DSA:3.30.950.10 139 257 1.5E-32 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 ProSitePatterns PS00211 ABC transporters family signature. 1763 1777 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 1046 1077 0.0069 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 676 728 0.02 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 8 208 2.16E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 471 602 2.16E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SMART SM00382 1034 1497 6.9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SMART SM00382 1565 1852 1.3 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SMART SM00382 664 951 0.083 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 1541 1894 5.1E-46 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 ProSitePatterns PS00211 ABC transporters family signature. 1420 1434 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 969 1.4E-284 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:1.20.1580.10 729 865 1.4E-40 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 653 958 4.9E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:1.20.1580.10 92 520 1.4E-83 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 1022 1215 1.01E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 1363 1502 1.01E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:1.20.1580.10 1104 1420 1.2E-63 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 1002 1045 0.063 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 10 44 0.0049 T 28-03-2018 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 SUPERFAMILY SSF52540 1551 1856 5.25E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 ProSitePatterns PS00211 ABC transporters family signature. 865 879 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Pfam PF00005 ABC transporter 655 883 3.5E-6 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03520 6dfa535495aed07b3a2178e4f1794045 1899 Gene3D G3DSA:3.40.50.300 633 675 0.012 T 28-03-2018 AFA_RS17500 df4ff37a0af6119dd28fc2bf14837077 372 Gene3D G3DSA:3.40.50.2000 1 166 2.9E-12 T 28-03-2018 AFA_RS17500 df4ff37a0af6119dd28fc2bf14837077 372 Gene3D G3DSA:3.40.50.2000 167 350 4.1E-27 T 28-03-2018 AFA_RS17500 df4ff37a0af6119dd28fc2bf14837077 372 Pfam PF00534 Glycosyl transferases group 1 188 336 3.2E-16 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS17500 df4ff37a0af6119dd28fc2bf14837077 372 SUPERFAMILY SSF53756 6 367 9.87E-55 T 28-03-2018 AFA_RS17500 df4ff37a0af6119dd28fc2bf14837077 372 Pfam PF13439 Glycosyltransferase Family 4 14 169 4.2E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 Pfam PF12697 Alpha/beta hydrolase family 35 276 4.7E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 6.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 228 242 6.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 6.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 6.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 Gene3D G3DSA:3.40.50.1820 2 284 2.4E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 SUPERFAMILY SSF53474 14 283 1.74E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00412 Epoxide hydrolase signature 259 281 1.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00412 Epoxide hydrolase signature 121 134 1.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS13935 b013a3ce97d7555d1fd2ceef9a8f1832 284 PRINTS PR00412 Epoxide hydrolase signature 62 77 1.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.899 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 Gene3D G3DSA:3.90.1170.10 2 137 1.0E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.1E-59 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 SUPERFAMILY SSF54686 1 134 3.14E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 7.1E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 7.1E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 7.1E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 7.1E-41 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.9E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFA_RS18235 afc4f21c248fa3526784b0dd42746f9b 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 2.1E-26 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Gene3D G3DSA:3.20.20.60 161 318 1.2E-60 T 28-03-2018 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Gene3D G3DSA:3.20.20.60 1 85 2.4E-16 T 28-03-2018 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 SUPERFAMILY SSF50800 73 168 2.09E-25 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 62 78 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 266 290 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 214 240 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 241 265 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 187 201 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 291 309 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 PRINTS PR01050 Pyruvate kinase family signature 310 326 3.4E-62 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 SUPERFAMILY SSF51621 3 78 9.42E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 SUPERFAMILY SSF51621 168 339 9.42E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Gene3D G3DSA:2.40.33.10 86 160 1.5E-23 T 28-03-2018 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Gene3D G3DSA:3.40.1380.20 319 471 2.6E-43 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 Pfam PF00224 Pyruvate kinase, barrel domain 5 334 3.4E-112 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 470 1.3E-147 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS02640 837b2238602bab98a6311c64354e4561 473 SUPERFAMILY SSF52935 320 470 7.85E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 Gene3D G3DSA:3.90.1150.10 349 432 3.0E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 Pfam PF00155 Aminotransferase class I and II 91 425 1.1E-22 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 SMART SM00345 11 70 1.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 Gene3D G3DSA:1.10.10.10 3 63 9.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 Gene3D G3DSA:3.40.640.10 64 348 5.3E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 9.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 SUPERFAMILY SSF53383 64 433 1.12E-51 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS08365 68478480eb90ce9ba5fd2ad65ddca29b 435 SUPERFAMILY SSF46785 9 72 1.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02855 6429e449408c3b277db6abd27b604eb6 294 SUPERFAMILY SSF103481 200 283 4.45E-8 T 28-03-2018 AFA_RS02855 6429e449408c3b277db6abd27b604eb6 294 Pfam PF00892 EamA-like transporter family 141 278 3.2E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS02855 6429e449408c3b277db6abd27b604eb6 294 Pfam PF00892 EamA-like transporter family 6 131 9.1E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS02855 6429e449408c3b277db6abd27b604eb6 294 SUPERFAMILY SSF103481 39 134 2.09E-10 T 28-03-2018 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Gene3D G3DSA:3.30.230.70 320 549 2.6E-59 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SMART SM00322 557 622 1.4E-13 T 28-03-2018 IPR004087 K Homology domain GO:0003676 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF00013 KH domain 562 619 4.7E-11 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SMART SM00316 625 695 3.1E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Gene3D G3DSA:3.30.1370.10 550 620 9.2E-16 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 PIRSF PIRSF005499 1 708 1.2E-295 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.135 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF55666 145 235 1.96E-30 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Gene3D G3DSA:1.10.10.400 235 319 3.8E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF50249 618 696 1.56E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF55666 455 554 5.89E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF54211 2 144 3.64E-51 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF03725 3' exoribonuclease family, domain 2 466 534 2.4E-5 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.4E-12 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Gene3D G3DSA:2.40.50.140 621 698 2.3E-21 T 28-03-2018 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Gene3D G3DSA:3.30.230.70 15 234 2.8E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF54791 560 644 6.45E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF00575 S1 RNA binding domain 624 695 8.8E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF46915 238 326 1.54E-16 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 1.4E-16 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 7.1E-23 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 5.4E-22 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS13465 c04bc5e5ee9e22e0e31ec4122d88702b 712 SUPERFAMILY SSF54211 298 493 5.57E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS17955 3c5dde9cd7292e9107c2fdc08b462956 181 Gene3D G3DSA:2.30.110.10 16 181 6.7E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS17955 3c5dde9cd7292e9107c2fdc08b462956 181 SUPERFAMILY SSF50475 20 178 1.42E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS17955 3c5dde9cd7292e9107c2fdc08b462956 181 Pfam PF01613 Flavin reductase like domain 28 176 4.7E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS17955 3c5dde9cd7292e9107c2fdc08b462956 181 SMART SM00903 28 177 1.2E-42 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 SUPERFAMILY SSF46785 9 91 1.34E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00170 daf4391977e93271251df511f2b0615e 293 Gene3D G3DSA:3.40.190.10 83 175 9.0E-5 T 28-03-2018 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 SUPERFAMILY SSF53850 95 291 4.65E-19 T 28-03-2018 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 8.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 8.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 8.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 Gene3D G3DSA:3.40.190.10 176 258 6.2E-12 T 28-03-2018 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 1.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00170 daf4391977e93271251df511f2b0615e 293 Pfam PF03466 LysR substrate binding domain 90 287 4.3E-16 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00170 daf4391977e93271251df511f2b0615e 293 Gene3D G3DSA:1.10.10.10 2 82 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 SUPERFAMILY SSF47203 288 457 4.99E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 454 1.2E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 486 587 7.2E-16 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Gene3D G3DSA:2.40.110.10 163 268 2.6E-23 T 28-03-2018 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Gene3D G3DSA:1.20.140.10 269 466 2.8E-41 T 28-03-2018 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 159 4.9E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Gene3D G3DSA:1.10.540.10 10 162 1.8E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 SUPERFAMILY SSF56645 39 279 6.28E-53 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS15935 a4d97cd3135b9a2d8673ac94dc1af520 591 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 165 271 9.9E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 283 1.3E-79 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 305 482 5.9E-76 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 SUPERFAMILY SSF143968 350 513 6.54E-66 T 28-03-2018 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 Gene3D G3DSA:1.20.5.570 487 514 1.6E-17 T 28-03-2018 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 Gene3D G3DSA:3.40.1670.10 350 486 7.3E-51 T 28-03-2018 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 458 4.8E-165 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 SUPERFAMILY SSF50475 3 349 8.63E-111 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS03345 c1ad05f6ac92507fe3f9b1a4611afeec 514 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 514 72.562 T 28-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 Pfam PF00202 Aminotransferase class-III 30 438 7.5E-113 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 17 437 2.3E-155 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 PIRSF PIRSF000521 16 445 9.2E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 Gene3D G3DSA:3.90.1150.10 328 446 2.8E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 Gene3D G3DSA:3.40.640.10 68 327 4.7E-68 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS04365 00d2fa9497f09523436ab4d7598f7fd2 446 SUPERFAMILY SSF53383 14 444 3.41E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS05155 a4664b0c423e49b917115d2ae0a1fe1e 554 SUPERFAMILY SSF109755 325 534 7.74E-17 T 28-03-2018 AFA_RS05155 a4664b0c423e49b917115d2ae0a1fe1e 554 Gene3D G3DSA:1.20.58.220 327 434 2.4E-5 T 28-03-2018 AFA_RS05155 a4664b0c423e49b917115d2ae0a1fe1e 554 Gene3D G3DSA:1.20.58.220 441 542 2.2E-5 T 28-03-2018 AFA_RS05155 a4664b0c423e49b917115d2ae0a1fe1e 554 Pfam PF02690 Na+/Pi-cotransporter 163 230 6.2E-11 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 AFA_RS05155 a4664b0c423e49b917115d2ae0a1fe1e 554 Pfam PF02690 Na+/Pi-cotransporter 16 148 3.3E-34 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Pfam PF00958 GMP synthase C terminal domain 441 527 3.1E-41 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 SUPERFAMILY SSF54810 401 528 5.75E-46 T 28-03-2018 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 528 54.592 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 200 3.4E-67 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Pfam PF02540 NAD synthase 214 288 9.9E-7 T 28-03-2018 IPR022310 NAD/GMP synthase AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Gene3D G3DSA:3.30.300.10 397 528 2.1E-50 T 28-03-2018 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Gene3D G3DSA:3.40.50.880 4 201 5.1E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Gene3D G3DSA:3.40.50.620 204 396 4.1E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 Pfam PF00117 Glutamine amidotransferase class-I 7 194 6.5E-35 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 SUPERFAMILY SSF52402 193 415 1.52E-57 T 28-03-2018 AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 SUPERFAMILY SSF52317 1 233 4.9E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07840 fea640c5a12bffdb8802363802855d8b 528 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 528 2.9E-146 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 Gene3D G3DSA:1.10.10.60 1 40 7.7E-13 T 28-03-2018 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 SUPERFAMILY SSF46689 11 80 1.34E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 Gene3D G3DSA:1.10.260.40 41 74 8.6E-13 T 28-03-2018 AFA_RS15985 241bf807bd85fa26756fbae9d5b09231 218 Gene3D G3DSA:1.10.357.10 75 212 2.9E-4 T 28-03-2018 AFA_RS06045 279be2fb16fc03d420e1fe1eb99ac6d6 237 SMART SM00382 29 228 1.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS06045 279be2fb16fc03d420e1fe1eb99ac6d6 237 SUPERFAMILY SSF52540 24 211 3.77E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS06045 279be2fb16fc03d420e1fe1eb99ac6d6 237 Gene3D G3DSA:3.40.50.300 1 214 7.2E-42 T 28-03-2018 AFA_RS06045 279be2fb16fc03d420e1fe1eb99ac6d6 237 Pfam PF00005 ABC transporter 25 174 2.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 SUPERFAMILY SSF48256 10 431 9.55E-162 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 430 2.2E-234 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 Gene3D G3DSA:1.10.580.10 346 412 2.8E-8 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 6.5E-129 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 Gene3D G3DSA:1.10.580.10 33 302 1.4E-87 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PIRSF PIRSF001369 41 434 2.9E-160 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 223 238 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 367 383 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 303 323 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 387 401 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 169 182 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS04870 2b336800894ac94fa02c693abdfbd3f2 434 PRINTS PR00143 Citrate synthase signature 245 273 1.4E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 AFA_RS11485 91bc661927e4753102082db388194933 224 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-32 T 28-03-2018 AFA_RS11485 91bc661927e4753102082db388194933 224 SUPERFAMILY SSF52172 1 180 3.13E-35 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS11485 91bc661927e4753102082db388194933 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 9.6E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11485 91bc661927e4753102082db388194933 224 Pfam PF00072 Response regulator receiver domain 3 113 1.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11485 91bc661927e4753102082db388194933 224 Gene3D G3DSA:1.10.10.10 122 224 5.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11485 91bc661927e4753102082db388194933 224 SMART SM00448 1 113 4.5E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11485 91bc661927e4753102082db388194933 224 SMART SM00862 147 220 1.0E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 Gene3D G3DSA:3.20.20.140 69 375 1.1E-56 T 28-03-2018 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 SUPERFAMILY SSF51338 18 75 3.17E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 Pfam PF01979 Amidohydrolase family 56 421 4.0E-60 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 SUPERFAMILY SSF51338 334 450 3.76E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 Gene3D G3DSA:2.30.40.10 6 68 4.5E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS09210 1a9c8ba2f5c74b1d64bdaa6e9c798949 458 SUPERFAMILY SSF51556 59 375 7.19E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 Pfam PF03466 LysR substrate binding domain 90 280 3.0E-37 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 SUPERFAMILY SSF46785 3 108 1.36E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 Gene3D G3DSA:3.40.190.10 174 261 8.2E-19 T 28-03-2018 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 Gene3D G3DSA:1.10.10.10 1 80 6.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 SUPERFAMILY SSF53850 91 289 1.18E-35 T 28-03-2018 AFA_RS15370 af21fd42cec4da3168e19271e57ca8c9 294 Gene3D G3DSA:3.40.190.10 88 173 4.0E-17 T 28-03-2018 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Pfam PF00330 Aconitase family (aconitate hydratase) 473 815 1.1E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 SUPERFAMILY SSF74778 1 160 1.57E-67 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 SUPERFAMILY SSF53732 377 854 4.19E-143 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Gene3D G3DSA:3.30.499.10 684 861 8.6E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Gene3D G3DSA:3.30.499.10 403 521 6.8E-11 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Gene3D G3DSA:3.20.19.10 162 361 9.3E-30 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 PIRSF PIRSF036687 1 859 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 3.0E-96 T 28-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 SUPERFAMILY SSF52016 162 370 1.6E-66 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Gene3D G3DSA:3.40.1060.10 522 683 1.3E-28 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS04795 51d3594d04a6ad4be283dab24ab009b3 861 Pfam PF11791 Aconitate B N-terminal domain 5 156 7.4E-64 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 SUPERFAMILY SSF53850 91 290 2.33E-36 T 28-03-2018 AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 Pfam PF03466 LysR substrate binding domain 91 286 2.0E-41 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 Gene3D G3DSA:1.10.10.10 1 83 7.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 Gene3D G3DSA:3.40.190.10 173 261 6.4E-22 T 28-03-2018 AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 Gene3D G3DSA:3.40.190.10 86 172 9.8E-14 T 28-03-2018 AFA_RS15340 e38fa82e701f41dce87529ee9745128c 297 SUPERFAMILY SSF46785 1 84 7.11E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 PIRSF PIRSF001467 33 215 3.0E-28 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 92 104 5.0E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 66 81 5.0E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 169 184 5.0E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 SUPERFAMILY SSF50891 49 214 1.75E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 53 207 2.7E-48 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 Gene3D G3DSA:2.40.100.10 31 215 1.5E-52 T 28-03-2018 IPR029000 Cyclophilin-like domain AFA_RS04540 c68938a5ae756c7d7ae098ae704e656e 215 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 87 104 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 AFA_RS07660 54c0320cff3c483b2d45d8edbb68a3e8 403 Gene3D G3DSA:3.40.50.10540 1 403 4.0E-137 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS07660 54c0320cff3c483b2d45d8edbb68a3e8 403 SUPERFAMILY SSF89796 3 396 5.76E-129 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS07660 54c0320cff3c483b2d45d8edbb68a3e8 403 Pfam PF02515 CoA-transferase family III 5 373 5.0E-124 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS00780 eaef569b780bedeba6df32b35d841636 301 Pfam PF00682 HMGL-like 4 273 9.1E-44 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFA_RS00780 eaef569b780bedeba6df32b35d841636 301 Gene3D G3DSA:3.20.20.70 1 293 4.2E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00780 eaef569b780bedeba6df32b35d841636 301 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00780 eaef569b780bedeba6df32b35d841636 301 SUPERFAMILY SSF51569 2 291 2.2E-66 T 28-03-2018 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 2.1E-126 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 Gene3D G3DSA:3.40.50.261 125 293 1.8E-49 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 SUPERFAMILY SSF51735 1 127 5.75E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 Pfam PF02629 CoA binding domain 6 102 3.4E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 SMART SM00881 4 103 3.3E-29 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 PIRSF PIRSF001553 1 293 7.5E-115 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 Pfam PF00549 CoA-ligase 156 271 5.3E-15 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 40.128 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 Gene3D G3DSA:3.40.50.720 1 124 5.4E-38 T 28-03-2018 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 SUPERFAMILY SSF52210 128 292 1.09E-51 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 2.6E-33 T 28-03-2018 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 2.6E-33 T 28-03-2018 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 2.6E-33 T 28-03-2018 AFA_RS10975 115e6cb94a063cfb5930b435c7b1b28f 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 2.6E-33 T 28-03-2018 AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 Gene3D G3DSA:3.40.190.10 86 188 0.0013 T 28-03-2018 AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 SUPERFAMILY SSF53850 177 321 2.78E-12 T 28-03-2018 AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 Gene3D G3DSA:1.10.10.10 3 85 4.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 Gene3D G3DSA:3.40.190.10 189 274 2.1E-6 T 28-03-2018 AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 7.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 SUPERFAMILY SSF46785 4 115 2.27E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03055 bf22bf222ce44fd7f0dc810ec6ccf10e 343 Pfam PF12727 PBP superfamily domain 116 304 8.5E-45 T 28-03-2018 IPR024370 PBP domain AFA_RS08405 8b6ace8d5bea131a5107879140c50a4c 348 Gene3D G3DSA:3.20.20.100 1 348 2.4E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS08405 8b6ace8d5bea131a5107879140c50a4c 348 SUPERFAMILY SSF51430 1 346 2.36E-107 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS08405 8b6ace8d5bea131a5107879140c50a4c 348 Pfam PF00248 Aldo/keto reductase family 16 339 6.6E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS11340 a99f23e9075be875cadd3cf21e4a27f1 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 158 169 1.9E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFA_RS11340 a99f23e9075be875cadd3cf21e4a27f1 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 90 107 1.9E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFA_RS11340 a99f23e9075be875cadd3cf21e4a27f1 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 170 185 1.9E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFA_RS11340 a99f23e9075be875cadd3cf21e4a27f1 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 147 157 1.9E-22 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFA_RS11340 a99f23e9075be875cadd3cf21e4a27f1 225 Pfam PF01478 Type IV leader peptidase family 82 189 2.5E-23 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 SUPERFAMILY SSF56349 85 367 7.06E-47 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 Gene3D G3DSA:1.10.443.10 185 381 6.9E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 85 139 3.0E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 Pfam PF12167 Arm DNA-binding domain 7 68 3.5E-18 T 28-03-2018 IPR022000 Min27-like integrase, DNA-binding domain AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 Pfam PF00589 Phage integrase family 197 360 8.6E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS12375 f8d5309fe31947e90f5383e600979806 395 Gene3D G3DSA:1.10.150.130 84 163 8.8E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 Gene3D G3DSA:3.30.420.40 2 142 1.9E-30 T 28-03-2018 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 268 400 1.9E-27 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 Gene3D G3DSA:3.40.630.30 243 407 8.8E-30 T 28-03-2018 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 Pfam PF00814 Glycoprotease family 38 133 2.4E-23 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 Gene3D G3DSA:3.30.420.40 149 242 0.23 T 28-03-2018 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 SUPERFAMILY SSF53067 115 231 2.98E-11 T 28-03-2018 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 233 1.8E-46 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 SUPERFAMILY SSF53067 5 107 3.5E-22 T 28-03-2018 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 Pfam PF00583 Acetyltransferase (GNAT) family 293 377 9.4E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS13305 95122e88ac74cde7ed8b35d1c30a72c9 410 SUPERFAMILY SSF55729 258 404 4.36E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS01130 0f03e8dd56c47294ed4748f8a3fb0a98 306 SUPERFAMILY SSF51569 1 290 1.88E-73 T 28-03-2018 AFA_RS01130 0f03e8dd56c47294ed4748f8a3fb0a98 306 Pfam PF00682 HMGL-like 6 279 1.7E-54 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFA_RS01130 0f03e8dd56c47294ed4748f8a3fb0a98 306 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 28-03-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111 AFA_RS01130 0f03e8dd56c47294ed4748f8a3fb0a98 306 Gene3D G3DSA:3.20.20.70 2 299 4.3E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 Gene3D G3DSA:1.10.10.10 22 159 3.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 SMART SM00347 44 142 5.3E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 Pfam PF01047 MarR family 49 107 1.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 SUPERFAMILY SSF46785 13 154 1.86E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS02195 8bb238f7267969ec3fe34e989e2d34f1 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 Pfam PF12951 Passenger-associated-transport-repeat 404 433 2.1E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 466 932 4.5E-36 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 318 328 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 Gene3D G3DSA:3.40.50.200 30 383 3.5E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 SMART SM00869 655 924 9.0E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 Gene3D G3DSA:2.40.128.130 610 933 2.5E-52 T 28-03-2018 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 Pfam PF03797 Autotransporter beta-domain 658 914 9.6E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 Pfam PF00082 Subtilase family 62 365 3.2E-44 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 SUPERFAMILY SSF52743 225 379 1.2E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 SUPERFAMILY SSF52743 44 192 1.2E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 4.1E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 PRINTS PR00723 Subtilisin serine protease family (S8) signature 317 333 4.1E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 PRINTS PR00723 Subtilisin serine protease family (S8) signature 62 81 4.1E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 SUPERFAMILY SSF103515 620 933 5.36E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16270 15674706d4d6ac8f1dccd0a2285c7d95 933 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 403 434 1.7E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS11965 594381f9e67787c830a893ead64b588d 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 7 215 9.2E-74 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFA_RS11965 594381f9e67787c830a893ead64b588d 225 Gene3D G3DSA:3.40.50.300 5 221 5.5E-48 T 28-03-2018 AFA_RS11965 594381f9e67787c830a893ead64b588d 225 Hamap MF_00238 Cytidylate kinase [cmk]. 7 221 32.636 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFA_RS11965 594381f9e67787c830a893ead64b588d 225 Pfam PF02224 Cytidylate kinase 9 216 3.1E-75 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFA_RS11965 594381f9e67787c830a893ead64b588d 225 SUPERFAMILY SSF52540 8 218 5.95E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 SUPERFAMILY SSF52540 196 444 3.24E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 Pfam PF03796 DnaB-like helicase C terminal domain 198 451 2.5E-112 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 Gene3D G3DSA:3.40.50.300 178 456 2.0E-65 T 28-03-2018 AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 18 453 1.9E-172 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 SMART SM00382 215 412 6.6E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 Pfam PF00772 DnaB-like helicase N terminal domain 18 119 4.3E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 SUPERFAMILY SSF48024 16 127 1.1E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFA_RS05215 f1ef128881f648d505c8a67a3961589e 456 Gene3D G3DSA:1.10.860.10 9 160 4.8E-45 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFA_RS03410 12272cd90120d8581832548515c5ccee 480 SUPERFAMILY SSF53720 3 476 1.44E-155 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS03410 12272cd90120d8581832548515c5ccee 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS03410 12272cd90120d8581832548515c5ccee 480 Gene3D G3DSA:3.40.309.10 263 459 7.8E-62 T 28-03-2018 AFA_RS03410 12272cd90120d8581832548515c5ccee 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS03410 12272cd90120d8581832548515c5ccee 480 Gene3D G3DSA:3.40.605.10 1 262 1.6E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS03410 12272cd90120d8581832548515c5ccee 480 Pfam PF00171 Aldehyde dehydrogenase family 20 473 3.5E-156 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS13085 0986b8e6729d5e6dbbf31ec38e2877d0 165 SUPERFAMILY SSF89069 18 79 9.81E-11 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 AFA_RS13085 0986b8e6729d5e6dbbf31ec38e2877d0 165 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 21 88 1.4E-9 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 Gene3D G3DSA:3.40.50.720 4 269 3.0E-51 T 28-03-2018 AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 SUPERFAMILY SSF51735 1 259 2.08E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13920 1af2a0638cef8571520047a947086f2a 271 Pfam PF00106 short chain dehydrogenase 9 196 5.0E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS11760 813c1f57dde07a68a5ec3a7dcca8323c 495 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 447 3.2E-116 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS11760 813c1f57dde07a68a5ec3a7dcca8323c 495 SUPERFAMILY SSF81442 15 472 1.83E-126 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS11760 813c1f57dde07a68a5ec3a7dcca8323c 495 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 14 469 2.2E-228 T 28-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFA_RS11760 813c1f57dde07a68a5ec3a7dcca8323c 495 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 208 263 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS11760 813c1f57dde07a68a5ec3a7dcca8323c 495 Gene3D G3DSA:1.20.210.10 13 474 3.0E-95 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12435 827cd217210e4037b149a06cdf43cff0 324 SUPERFAMILY SSF103473 9 315 1.31E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12435 827cd217210e4037b149a06cdf43cff0 324 Pfam PF07690 Major Facilitator Superfamily 10 171 1.2E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS12435 827cd217210e4037b149a06cdf43cff0 324 Gene3D G3DSA:1.20.1250.20 7 134 1.3E-18 T 28-03-2018 AFA_RS12435 827cd217210e4037b149a06cdf43cff0 324 Gene3D G3DSA:1.20.1250.20 135 317 9.5E-14 T 28-03-2018 AFA_RS14990 96af4b0905838f849ad8e1b4eb0bf5cf 255 SMART SM00382 28 222 9.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS14990 96af4b0905838f849ad8e1b4eb0bf5cf 255 Gene3D G3DSA:3.40.50.300 1 254 3.1E-54 T 28-03-2018 AFA_RS14990 96af4b0905838f849ad8e1b4eb0bf5cf 255 SUPERFAMILY SSF52540 3 244 4.49E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14990 96af4b0905838f849ad8e1b4eb0bf5cf 255 Pfam PF00005 ABC transporter 20 173 1.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 PIRSF PIRSF036298 1 304 2.7E-153 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 289 1.5E-144 T 28-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 8.2E-23 T 28-03-2018 IPR015246 Formate dehydrogenase, transmembrane AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Gene3D G3DSA:3.30.70.20 43 113 5.7E-22 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Gene3D G3DSA:3.30.70.20 156 205 7.5E-5 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Gene3D G3DSA:3.30.70.20 20 42 0.0021 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Gene3D G3DSA:3.30.70.20 114 155 3.3E-17 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 SUPERFAMILY SSF54862 29 271 5.86E-71 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Gene3D G3DSA:1.20.5.480 249 291 1.9E-21 T 28-03-2018 AFA_RS16830 43a5eec4099635553eeca478efa7a0fe 305 Pfam PF13247 4Fe-4S dicluster domain 92 188 2.6E-23 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS08120 71657ff1caf41062841f221108d63e1d 206 SUPERFAMILY SSF52833 1 85 4.26E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS08120 71657ff1caf41062841f221108d63e1d 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 9 75 1.1E-12 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS08120 71657ff1caf41062841f221108d63e1d 206 Gene3D G3DSA:1.20.1050.10 99 201 9.9E-23 T 28-03-2018 AFA_RS08120 71657ff1caf41062841f221108d63e1d 206 Gene3D G3DSA:3.40.30.10 1 98 2.5E-29 T 28-03-2018 AFA_RS08120 71657ff1caf41062841f221108d63e1d 206 SUPERFAMILY SSF47616 80 203 2.92E-26 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 20 43 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 103 120 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 122 140 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 319 345 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 82 100 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PRINTS PR00067 Catalase signature 287 314 4.4E-75 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 SUPERFAMILY SSF56634 3 474 5.1E-212 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 Gene3D G3DSA:2.40.180.10 1 356 2.1E-164 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 Pfam PF00199 Catalase 7 386 3.7E-191 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 Pfam PF06628 Catalase-related immune-responsive 415 474 1.9E-24 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 SMART SM01060 7 390 4.7E-286 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS18585 568600c82887bd2b7b540c916fe3c8f4 480 PIRSF PIRSF038928 1 479 1.3E-225 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 SMART SM01004 10 334 4.7E-230 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 Gene3D G3DSA:3.20.20.70 3 338 3.8E-148 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 9.3E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 PIRSF PIRSF001415 3 337 2.6E-145 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 332 1.2E-137 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFA_RS17935 5df56e3455ac5f0867309c6bd083a91d 339 SUPERFAMILY SSF51569 9 336 2.34E-142 T 28-03-2018 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 SUPERFAMILY SSF69055 300 394 6.8E-28 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 147 237 4.2E-38 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 393 3.7E-137 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 133 9.5E-37 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Pfam PF13288 DXP reductoisomerase C-terminal domain 269 388 2.7E-37 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 SUPERFAMILY SSF51735 4 151 1.46E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 SUPERFAMILY SSF55347 127 272 1.7E-61 T 28-03-2018 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 6 393 44.549 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 PIRSF PIRSF006205 3 399 9.1E-143 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Gene3D G3DSA:3.40.50.720 3 151 1.3E-42 T 28-03-2018 AFA_RS10180 f3bd1ca463dd17f31795ce5622cad235 400 Gene3D G3DSA:1.10.1740.10 310 396 3.0E-26 T 28-03-2018 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 73 1.4E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 Gene3D G3DSA:3.40.50.10490 98 276 7.5E-36 T 28-03-2018 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 Pfam PF01380 SIS domain 122 250 1.4E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 SUPERFAMILY SSF53697 91 275 3.93E-41 T 28-03-2018 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 SUPERFAMILY SSF46689 2 76 2.15E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18130 7b4317b7f0aaea02a97874cb6dd8e42e 277 Gene3D G3DSA:1.10.10.10 1 97 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04980 087542634faa525aa809e1e6ab09a77c 255 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 29 244 7.1E-46 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFA_RS04980 087542634faa525aa809e1e6ab09a77c 255 SUPERFAMILY SSF64438 9 252 5.86E-72 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AFA_RS04980 087542634faa525aa809e1e6ab09a77c 255 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 23 249 5.0E-71 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFA_RS04980 087542634faa525aa809e1e6ab09a77c 255 Gene3D G3DSA:3.60.140.10 2 255 7.6E-83 T 28-03-2018 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 SUPERFAMILY SSF48019 244 429 3.36E-72 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 SUPERFAMILY SSF52540 8 227 5.4E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 158 3.7E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Gene3D G3DSA:1.20.272.10 243 337 3.0E-36 T 28-03-2018 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Pfam PF12002 MgsA AAA+ ATPase C terminal 259 425 7.8E-65 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Gene3D G3DSA:3.40.50.300 2 150 1.1E-29 T 28-03-2018 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Gene3D G3DSA:1.10.3710.10 340 437 2.5E-34 T 28-03-2018 AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 SMART SM00382 46 162 2.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Pfam PF16193 AAA C-terminal domain 183 258 2.9E-23 T 28-03-2018 IPR032423 AAA C-terminal domain AFA_RS13535 a99a561db1ebeb3e89f3fa1064b23997 437 Gene3D G3DSA:1.10.8.60 151 233 1.1E-20 T 28-03-2018 AFA_RS02135 f86406abbedf5d4ba6fd40f92cc36c56 307 PIRSF PIRSF017082 2 307 3.2E-75 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02135 f86406abbedf5d4ba6fd40f92cc36c56 307 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 32 303 6.5E-78 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02135 f86406abbedf5d4ba6fd40f92cc36c56 307 SUPERFAMILY SSF53850 110 269 1.74E-12 T 28-03-2018 AFA_RS02135 f86406abbedf5d4ba6fd40f92cc36c56 307 Gene3D G3DSA:3.40.190.10 41 280 5.7E-11 T 28-03-2018 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 SUPERFAMILY SSF54292 2 79 1.97E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 SUPERFAMILY SSF55961 223 361 4.67E-20 T 28-03-2018 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Gene3D G3DSA:3.10.20.30 1 75 7.3E-26 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Gene3D G3DSA:3.30.530.20 220 374 1.7E-16 T 28-03-2018 IPR023393 START-like domain AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 59 1.3E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Gene3D G3DSA:1.10.150.120 76 191 1.3E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 220 358 5.1E-15 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 Pfam PF01799 [2Fe-2S] binding domain 74 146 6.8E-20 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS15080 099bbd391ec8c8ce9a76354910f69ce1 395 SUPERFAMILY SSF47741 85 165 5.23E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS02730 569d24c102b9466953a867fed252c918 369 Pfam PF13439 Glycosyltransferase Family 4 10 169 3.2E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS02730 569d24c102b9466953a867fed252c918 369 Pfam PF00534 Glycosyl transferases group 1 184 342 9.9E-38 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS02730 569d24c102b9466953a867fed252c918 369 SUPERFAMILY SSF53756 3 364 6.54E-79 T 28-03-2018 AFA_RS02730 569d24c102b9466953a867fed252c918 369 Gene3D G3DSA:3.40.50.2000 182 349 2.2E-40 T 28-03-2018 AFA_RS02730 569d24c102b9466953a867fed252c918 369 Gene3D G3DSA:3.40.50.2000 2 178 1.2E-28 T 28-03-2018 AFA_RS08830 65f3d520afadf40365b76d422425b76c 442 Pfam PF00535 Glycosyl transferase family 2 77 244 5.4E-34 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS08830 65f3d520afadf40365b76d422425b76c 442 Gene3D G3DSA:3.90.550.10 52 332 4.9E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS08830 65f3d520afadf40365b76d422425b76c 442 SUPERFAMILY SSF53448 62 333 2.5E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS08830 65f3d520afadf40365b76d422425b76c 442 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 31 437 1.5E-184 T 28-03-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 Pfam PF04355 SmpA / OmlA family 47 113 2.5E-17 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 192 209 1.1E-5 T 28-03-2018 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 163 189 1.1E-5 T 28-03-2018 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 210 229 1.1E-5 T 28-03-2018 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 SUPERFAMILY SSF103088 138 253 1.57E-31 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 Pfam PF00691 OmpA family 146 233 5.8E-20 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 Gene3D G3DSA:3.30.1330.60 54 257 9.7E-34 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01021 OMPA domain signature 192 208 3.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01021 OMPA domain signature 146 168 3.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS14220 79d36b7849e61c517bd217be4d40ad11 257 PRINTS PR01021 OMPA domain signature 177 192 3.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS16535 e2f81c8e27f3e6e2d42d7fdfefdb3a96 337 SUPERFAMILY SSF53850 26 293 3.57E-27 T 28-03-2018 AFA_RS16535 e2f81c8e27f3e6e2d42d7fdfefdb3a96 337 Gene3D G3DSA:3.40.190.10 21 136 4.5E-10 T 28-03-2018 AFA_RS16535 e2f81c8e27f3e6e2d42d7fdfefdb3a96 337 Pfam PF13379 NMT1-like family 20 263 8.6E-27 T 28-03-2018 AFA_RS16535 e2f81c8e27f3e6e2d42d7fdfefdb3a96 337 Gene3D G3DSA:3.40.190.10 137 336 1.6E-27 T 28-03-2018 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 SMART SM00347 34 134 2.7E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 Gene3D G3DSA:1.10.10.10 3 151 1.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 Pfam PF12802 MarR family 41 98 5.7E-11 T 28-03-2018 AFA_RS01485 af71a646140377a00cfa0b4c929f8107 153 SUPERFAMILY SSF46785 14 149 1.28E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 SUPERFAMILY SSF51306 93 214 2.79E-33 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 Hamap MF_00015 LexA repressor [lexA]. 4 216 31.28 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 Pfam PF01726 LexA DNA binding domain 4 66 1.2E-27 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 129 139 3.3E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 168 180 3.3E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 140 151 3.3E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 Pfam PF00717 Peptidase S24-like 132 198 2.1E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 Gene3D G3DSA:1.10.10.10 1 71 8.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 TIGRFAM TIGR00498 lexA: repressor LexA 4 215 2.9E-68 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 SUPERFAMILY SSF46785 4 71 6.65E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07685 d00024fc0e6fa227bbd16c87be94c007 219 Gene3D G3DSA:2.10.109.10 98 216 1.3E-23 T 28-03-2018 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 8 442 2.6E-169 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 186 352 7.3E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 163 2.0E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Hamap MF_00195 GTPase Der [der]. 7 445 37.19 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Gene3D G3DSA:1.20.120.430 75 254 1.5E-46 T 28-03-2018 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Gene3D G3DSA:1.20.120.430 255 375 2.3E-12 T 28-03-2018 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 SUPERFAMILY SSF52540 9 170 1.59E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 PIRSF PIRSF006485 6 450 2.6E-168 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 78 96 7.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 7.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Pfam PF01926 50S ribosome-binding GTPase 189 306 3.0E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Pfam PF01926 50S ribosome-binding GTPase 10 125 4.9E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Gene3D G3DSA:3.30.300.20 376 443 1.4E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Gene3D G3DSA:1.20.120.430 2 74 3.4E-13 T 28-03-2018 AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 362 442 3.4E-27 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like AFA_RS11550 94e9706f6ebf98639a6f654e2b5f6002 452 SUPERFAMILY SSF52540 143 448 7.76E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13005 486f2fd188fcfb94ad244a60057a3cf1 437 Gene3D G3DSA:3.20.20.30 5 436 2.2E-93 T 28-03-2018 AFA_RS13005 486f2fd188fcfb94ad244a60057a3cf1 437 PIRSF PIRSF000337 5 436 9.5E-145 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS13005 486f2fd188fcfb94ad244a60057a3cf1 437 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 424 1.2E-154 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS13005 486f2fd188fcfb94ad244a60057a3cf1 437 SUPERFAMILY SSF51679 9 429 6.04E-118 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS13005 486f2fd188fcfb94ad244a60057a3cf1 437 Pfam PF00296 Luciferase-like monooxygenase 16 380 3.0E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 SUPERFAMILY SSF53474 33 391 2.58E-104 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 24 395 48.73 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 PIRSF PIRSF000443 7 401 6.3E-145 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 Pfam PF00561 alpha/beta hydrolase fold 67 382 3.1E-36 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 37 392 7.3E-143 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AFA_RS01830 b974bd5f15dd04ce78c830708fff53c0 414 Gene3D G3DSA:3.40.50.1820 46 396 7.9E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 Gene3D G3DSA:1.20.120.530 86 235 6.8E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 Pfam PF07729 FCD domain 100 220 2.4E-25 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 SMART SM00345 31 89 1.3E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 SMART SM00895 99 221 4.8E-20 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 SUPERFAMILY SSF46785 24 93 2.07E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 Gene3D G3DSA:1.10.10.10 11 85 8.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 89 1.3E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17835 5b4d81f2976a73d26e594deef28866d1 235 SUPERFAMILY SSF48008 99 228 2.43E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00210 f0a87590fbb0c022dd3981cab2cda239 325 PIRSF PIRSF017082 1 325 8.4E-77 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00210 f0a87590fbb0c022dd3981cab2cda239 325 SUPERFAMILY SSF53850 102 282 1.16E-11 T 28-03-2018 AFA_RS00210 f0a87590fbb0c022dd3981cab2cda239 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 7.4E-77 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00210 f0a87590fbb0c022dd3981cab2cda239 325 Gene3D G3DSA:3.40.190.10 164 297 2.0E-9 T 28-03-2018 AFA_RS00210 f0a87590fbb0c022dd3981cab2cda239 325 Gene3D G3DSA:3.40.190.10 11 163 0.17 T 28-03-2018 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 SUPERFAMILY SSF63411 263 443 5.9E-24 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 SUPERFAMILY SSF63411 735 919 7.33E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Gene3D G3DSA:3.30.830.10 260 461 1.7E-22 T 28-03-2018 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 74 97 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 SUPERFAMILY SSF63411 42 254 6.63E-54 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 SUPERFAMILY SSF63411 523 718 2.14E-30 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Gene3D G3DSA:3.30.830.10 716 923 6.6E-27 T 28-03-2018 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Pfam PF00675 Insulinase (Peptidase family M16) 516 637 9.9E-6 T 28-03-2018 IPR011765 Peptidase M16, N-terminal AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Pfam PF00675 Insulinase (Peptidase family M16) 56 199 5.5E-22 T 28-03-2018 IPR011765 Peptidase M16, N-terminal AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Pfam PF05193 Peptidase M16 inactive domain 207 383 3.2E-28 T 28-03-2018 IPR007863 Peptidase M16, C-terminal AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Pfam PF05193 Peptidase M16 inactive domain 668 847 2.0E-22 T 28-03-2018 IPR007863 Peptidase M16, C-terminal AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Gene3D G3DSA:3.30.830.10 39 256 1.4E-57 T 28-03-2018 AFA_RS13740 325202a19da5dc7acd71696427114c86 950 Gene3D G3DSA:3.30.830.10 506 715 4.0E-30 T 28-03-2018 AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 88 181 2.0E-14 T 28-03-2018 AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 Gene3D G3DSA:1.10.357.10 52 186 5.6E-13 T 28-03-2018 AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 49 4.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 Gene3D G3DSA:1.10.10.60 3 49 7.0E-10 T 28-03-2018 AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 SUPERFAMILY SSF48498 78 183 2.36E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS01605 66d0e98e738dd8a6176dc7e237397220 204 SUPERFAMILY SSF46689 4 68 1.9E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 Gene3D G3DSA:3.10.180.10 155 356 3.4E-59 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 Gene3D G3DSA:3.10.180.10 2 154 1.4E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 PIRSF PIRSF009283 1 356 1.2E-115 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 160 278 1.9E-18 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 SUPERFAMILY SSF54593 5 342 3.36E-83 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 12 355 5.4E-123 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AFA_RS14305 b4d5aee200359290d39e8000c64ce85a 358 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 5 142 2.6E-69 T 28-03-2018 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 509 45.541 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 SUPERFAMILY SSF48557 2 502 4.71E-189 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 Pfam PF00221 Aromatic amino acid lyase 12 476 7.8E-189 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 507 3.0E-213 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 Gene3D G3DSA:1.10.275.10 3 198 1.5E-72 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS17670 2911075a0affb8ad9753f5b7e9abf45e 511 Gene3D G3DSA:1.20.200.10 200 510 1.1E-120 T 28-03-2018 AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 Pfam PF13545 Crp-like helix-turn-helix domain 179 248 4.0E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 SUPERFAMILY SSF51206 36 170 2.09E-29 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 SMART SM00419 193 241 4.9E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 SUPERFAMILY SSF46785 179 248 6.96E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 Gene3D G3DSA:2.60.120.10 30 175 1.4E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 SMART SM00100 41 159 2.3E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 Pfam PF00027 Cyclic nucleotide-binding domain 63 144 3.5E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS01295 4ab27aaa88c4d71e7a21aec9ae8b68d3 256 Gene3D G3DSA:1.10.10.10 176 251 6.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 SUPERFAMILY SSF55120 10 226 1.58E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 225 2.1E-14 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 182 6.4E-56 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 220 6.7E-77 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 Gene3D G3DSA:3.30.2350.10 9 232 6.5E-82 T 28-03-2018 AFA_RS05110 5783ad8868b23c4f80ff017f4ef483ed 250 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 247 18.101 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 Gene3D G3DSA:1.10.10.60 8 22 0.006 T 28-03-2018 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 1.4E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 Gene3D G3DSA:1.10.1660.10 65 135 6.9E-10 T 28-03-2018 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 Gene3D G3DSA:1.10.1660.10 23 64 5.0E-18 T 28-03-2018 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 SUPERFAMILY SSF46955 9 131 5.49E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 9 148 3.7E-60 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 Pfam PF13411 MerR HTH family regulatory protein 10 76 1.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07640 847c4b3d245a40bb9362f73cd5f5d222 152 SMART SM00422 9 77 4.1E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 Gene3D G3DSA:3.40.640.10 202 336 7.2E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 Gene3D G3DSA:3.90.1150.10 337 448 3.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 Gene3D G3DSA:3.90.1150.10 7 193 3.6E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 SUPERFAMILY SSF53383 19 446 2.45E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 Pfam PF00202 Aminotransferase class-III 34 440 2.6E-86 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 PIRSF PIRSF000521 194 447 1.1E-16 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS14185 91a67245b031a17cd5704e5f2a34cf86 448 PIRSF PIRSF000521 26 146 0.0063 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 Pfam PF01545 Cation efflux family 20 212 4.2E-47 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 Gene3D G3DSA:1.20.1510.10 14 211 1.6E-45 T 28-03-2018 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 Gene3D G3DSA:3.30.70.1350 212 298 4.6E-21 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 16 293 2.3E-64 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 SUPERFAMILY SSF160240 216 294 9.02E-21 T 28-03-2018 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 SUPERFAMILY SSF161111 12 214 1.28E-53 T 28-03-2018 AFA_RS02545 0428eb2783fc6846b3e229408fb49199 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 218 293 1.5E-21 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 20 86 5.0E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.696 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 Gene3D G3DSA:1.20.58.110 1 87 1.2E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 SUPERFAMILY SSF46992 3 86 6.54E-30 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07335 e78d00755daca3da6dc1fe62ac9978c1 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 2.3E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:2.60.40.10 746 836 0.085 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:2.60.40.10 635 738 2.5E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:1.20.120.330 1161 1299 0.015 T 28-03-2018 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 SUPERFAMILY SSF49265 642 729 2.96E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:2.60.40.10 115 237 0.34 T 28-03-2018 IPR013783 Immunoglobulin-like fold AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:3.30.70.1340 878 907 0.22 T 28-03-2018 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Pfam PF09327 Domain of unknown function (DUF1983) 1494 1571 2.1E-18 T 28-03-2018 IPR015406 Domain of unknown function DUF1983 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:1.20.120.330 948 1098 4.8E-11 T 28-03-2018 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Pfam PF13550 Putative phage tail protein 366 518 2.8E-21 T 28-03-2018 IPR032876 Tip attachment protein J AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:2.10.10.20 908 947 0.0011 T 28-03-2018 AFA_RS07110 4ca7b7305d326461e0fed413394e9371 1650 Gene3D G3DSA:1.20.5.730 1348 1434 4.7E-4 T 28-03-2018 AFA_RS03050 ef1177b4b9ce739cb8acb29a4f96c5a0 168 PIRSF PIRSF000216 2 168 5.9E-41 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03050 ef1177b4b9ce739cb8acb29a4f96c5a0 168 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 24 163 2.1E-37 T 28-03-2018 AFA_RS03050 ef1177b4b9ce739cb8acb29a4f96c5a0 168 SUPERFAMILY SSF52833 26 163 4.03E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS03050 ef1177b4b9ce739cb8acb29a4f96c5a0 168 Gene3D G3DSA:3.40.30.10 83 167 4.3E-12 T 28-03-2018 AFA_RS14325 aa1e6fed693f642cbe8f4683066767cf 200 Pfam PF11161 Protein of unknown function (DUF2946) 1 150 4.0E-52 T 28-03-2018 IPR021332 Protein of unknown function DUF2944 AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 27 164 5.1E-54 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 4 372 36.599 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 Pfam PF13286 Phosphohydrolase-associated domain 285 369 1.1E-26 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 Gene3D G3DSA:1.10.3210.10 17 371 7.8E-77 T 28-03-2018 AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 SUPERFAMILY SSF109604 16 372 2.79E-83 T 28-03-2018 AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 SMART SM00471 60 208 7.3E-11 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS17880 a5800efc5c0679755be3f7815e193b76 374 Pfam PF01966 HD domain 64 198 3.2E-14 T 28-03-2018 IPR006674 HD domain AFA_RS15495 d8d24611c0e99b50246e3ea2f839406f 455 Gene3D G3DSA:2.70.70.10 224 413 2.2E-43 T 28-03-2018 AFA_RS15495 d8d24611c0e99b50246e3ea2f839406f 455 SUPERFAMILY SSF51261 178 412 4.5E-71 T 28-03-2018 IPR011055 Duplicated hybrid motif AFA_RS15495 d8d24611c0e99b50246e3ea2f839406f 455 Pfam PF01551 Peptidase family M23 314 410 2.6E-34 T 28-03-2018 IPR016047 Peptidase M23 AFA_RS17375 bf5c290ee404eb282aab05510b3988bb 282 SUPERFAMILY SSF53335 14 229 6.63E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS17375 bf5c290ee404eb282aab05510b3988bb 282 PIRSF PIRSF018249 6 282 9.0E-72 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 AFA_RS17375 bf5c290ee404eb282aab05510b3988bb 282 Gene3D G3DSA:3.40.50.150 10 282 5.8E-41 T 28-03-2018 AFA_RS17375 bf5c290ee404eb282aab05510b3988bb 282 Pfam PF13649 Methyltransferase domain 100 184 3.6E-10 T 28-03-2018 AFA_RS14275 c3279120e9d54c0a995098210566b1b1 199 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 28 2.6E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14275 c3279120e9d54c0a995098210566b1b1 199 Gene3D G3DSA:3.10.610.10 39 146 3.0E-4 T 28-03-2018 AFA_RS14275 c3279120e9d54c0a995098210566b1b1 199 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 8.3E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14275 c3279120e9d54c0a995098210566b1b1 199 SUPERFAMILY SSF54523 40 194 2.77E-7 T 28-03-2018 AFA_RS14275 c3279120e9d54c0a995098210566b1b1 199 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14925 58fc7c1feae56e57619cff8935ae7d97 138 Pfam PF06078 Bacterial protein of unknown function (DUF937) 4 110 2.3E-9 T 28-03-2018 IPR009282 Protein of unknown function DUF937 AFA_RS14925 58fc7c1feae56e57619cff8935ae7d97 138 Gene3D G3DSA:1.10.10.690 1 136 5.9E-28 T 28-03-2018 AFA_RS14925 58fc7c1feae56e57619cff8935ae7d97 138 SUPERFAMILY SSF140804 20 130 2.75E-25 T 28-03-2018 IPR027405 YidB-like AFA_RS11875 b8e31326cce499e91a3a6eae3a0f977c 223 Pfam PF00293 NUDIX domain 47 159 1.8E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS11875 b8e31326cce499e91a3a6eae3a0f977c 223 SUPERFAMILY SSF55811 25 202 7.08E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS11875 b8e31326cce499e91a3a6eae3a0f977c 223 Gene3D G3DSA:3.90.79.10 37 207 1.3E-36 T 28-03-2018 AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 SUPERFAMILY SSF50331 255 349 5.67E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 Gene3D G3DSA:3.40.50.300 1 253 6.9E-71 T 28-03-2018 AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 SUPERFAMILY SSF52540 3 239 8.71E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 SMART SM00382 27 210 2.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 Pfam PF08402 TOBE domain 276 350 8.6E-8 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS00180 5678254e252d6e59f76223f1003e41b5 354 Pfam PF00005 ABC transporter 19 160 2.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 SMART SM00342 241 325 5.3E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 Pfam PF14525 AraC-binding-like domain 30 199 3.7E-26 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 SUPERFAMILY SSF46689 277 325 3.81E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 SUPERFAMILY SSF46689 224 275 1.25E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 278 321 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 Gene3D G3DSA:1.10.10.60 278 332 1.2E-4 T 28-03-2018 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 Gene3D G3DSA:1.10.10.60 220 277 2.1E-12 T 28-03-2018 AFA_RS00550 5de9b16045826e408dddbd4624689e4a 335 Pfam PF12833 Helix-turn-helix domain 247 324 5.4E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 Gene3D G3DSA:1.10.10.60 230 284 1.2E-11 T 28-03-2018 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 SUPERFAMILY SSF46689 179 230 2.69E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 SUPERFAMILY SSF46689 232 277 8.06E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 Pfam PF12852 Cupin 4 162 1.7E-27 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 Pfam PF12833 Helix-turn-helix domain 202 279 1.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 Gene3D G3DSA:1.10.10.60 156 229 1.9E-9 T 28-03-2018 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 Gene3D G3DSA:2.60.120.280 36 155 7.4E-7 T 28-03-2018 AFA_RS02370 9bd45ff2f811e16b963c0fceb603f2f7 284 SMART SM00342 196 278 1.6E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11470 7d0424718d4697ba9f46b0ba94118f72 322 Pfam PF13478 XdhC Rossmann domain 169 310 9.2E-37 T 28-03-2018 IPR027051 XdhC Rossmann domain AFA_RS11470 7d0424718d4697ba9f46b0ba94118f72 322 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 19 311 3.4E-92 T 28-03-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC AFA_RS11470 7d0424718d4697ba9f46b0ba94118f72 322 Gene3D G3DSA:3.40.50.20 166 256 5.6E-4 T 28-03-2018 AFA_RS11470 7d0424718d4697ba9f46b0ba94118f72 322 Pfam PF02625 XdhC and CoxI family 12 68 3.3E-10 T 28-03-2018 IPR003777 XdhC- CoxI AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 36 59 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 87 1.1E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 Gene3D G3DSA:4.10.640.10 3 90 1.8E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 PRINTS PR00974 Ribosomal protein S18 family signature 53 60 1.8E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 PRINTS PR00974 Ribosomal protein S18 family signature 75 85 1.8E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 PRINTS PR00974 Ribosomal protein S18 family signature 43 53 1.8E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 PRINTS PR00974 Ribosomal protein S18 family signature 61 75 1.8E-15 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 17 88 20.152 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 Pfam PF01084 Ribosomal protein S18 34 83 1.1E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 36 87 4.0E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05205 1112071e647ca3e9d26bb5a9782b729f 90 SUPERFAMILY SSF46911 15 89 3.14E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 Gene3D G3DSA:3.10.290.10 13 85 5.5E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 28 313 1.1E-75 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 Pfam PF00849 RNA pseudouridylate synthase 103 257 5.7E-32 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 SUPERFAMILY SSF55120 89 318 2.67E-66 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 Pfam PF01479 S4 domain 29 74 7.3E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 Gene3D G3DSA:3.30.2350.10 93 319 6.9E-65 T 28-03-2018 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 SMART SM00363 28 93 1.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 SUPERFAMILY SSF55174 29 78 1.79E-11 T 28-03-2018 AFA_RS04975 277e936c703a34edb0dac62258ceea73 321 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 145 159 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS05275 19d27ed1fc317307832142483f6153c9 287 Gene3D G3DSA:1.10.600.10 2 279 7.5E-94 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS05275 19d27ed1fc317307832142483f6153c9 287 Pfam PF00494 Squalene/phytoene synthase 13 263 1.8E-83 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 AFA_RS05275 19d27ed1fc317307832142483f6153c9 287 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 5.1E-119 T 28-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 AFA_RS05275 19d27ed1fc317307832142483f6153c9 287 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFA_RS05275 19d27ed1fc317307832142483f6153c9 287 SUPERFAMILY SSF48576 3 277 6.72E-93 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Pfam PF00171 Aldehyde dehydrogenase family 650 1094 1.1E-114 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Gene3D G3DSA:1.20.5.550 86 132 4.6E-14 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Gene3D G3DSA:3.40.309.10 891 1080 5.7E-49 T 28-03-2018 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Gene3D G3DSA:3.20.20.220 168 595 7.0E-110 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 139 250 5.4E-47 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 602 1097 1.7E-222 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 SUPERFAMILY SSF81935 85 252 3.14E-63 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Gene3D G3DSA:3.40.605.10 633 890 3.8E-71 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 PIRSF PIRSF000197 72 1257 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 Pfam PF01619 Proline dehydrogenase 261 560 1.2E-101 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 902 913 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 SUPERFAMILY SSF51730 253 602 2.67E-122 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 SUPERFAMILY SSF47598 4 45 5.78E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFA_RS07435 7a0f601387b89365f2a4cf2daea505db 1257 SUPERFAMILY SSF53720 630 1097 1.83E-127 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 Gene3D G3DSA:3.40.470.10 115 304 3.5E-43 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 131 302 1.9E-42 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 Pfam PF03167 Uracil DNA glycosylase superfamily 152 295 4.8E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 SMART SM00986 145 296 7.9E-29 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 SUPERFAMILY SSF52141 120 304 5.23E-44 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFA_RS13300 2feaa9947d0f250457267dccf944680e 305 SMART SM00987 145 296 7.9E-29 T 28-03-2018 AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 210 241 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 SMART SM00922 163 258 6.1E-16 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 144 2.6E-28 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 Pfam PF13378 Enolase C-terminal domain-like 167 378 1.3E-45 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 SUPERFAMILY SSF51604 132 385 4.19E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 119 144 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 Gene3D G3DSA:3.20.20.120 149 392 3.4E-56 T 28-03-2018 IPR029065 Enolase C-terminal domain-like AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 SUPERFAMILY SSF54826 21 145 6.48E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 Gene3D G3DSA:3.30.390.10 15 148 5.8E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFA_RS08240 b136f21008e696fd0c0d5279e9bbb84e 396 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 21 386 8.0E-164 T 28-03-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 Gene3D G3DSA:3.50.50.60 3 161 3.6E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 SUPERFAMILY SSF51905 114 191 9.02E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 SUPERFAMILY SSF51905 1 56 9.02E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 SUPERFAMILY SSF51905 219 361 9.02E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PIRSF PIRSF000350 1 456 1.2E-58 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 Gene3D G3DSA:3.40.50.720 168 352 8.3E-22 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 322 6.5E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.8E-18 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 4.8E-18 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 4.8E-18 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 4.8E-18 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 4.8E-18 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 450 1.1E-13 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 3.6E-44 T 28-03-2018 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 Gene3D G3DSA:3.30.390.30 353 461 2.6E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS10315 6b3033e78e1a97e78c09f321721b329e 461 SUPERFAMILY SSF55424 346 457 8.25E-23 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AFA_RS03500 ac0386c5f402146730bf40d79d25dab1 223 Pfam PF04752 ChaC-like protein 46 212 1.8E-42 T 28-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 AFA_RS03500 ac0386c5f402146730bf40d79d25dab1 223 Gene3D G3DSA:3.10.490.10 31 216 3.8E-29 T 28-03-2018 AFA_RS03500 ac0386c5f402146730bf40d79d25dab1 223 SUPERFAMILY SSF110857 46 163 1.18E-8 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like AFA_RS01195 6c4ebaeb38b53bb507e71baef8b3352b 441 Gene3D G3DSA:3.40.50.2000 232 425 4.0E-15 T 28-03-2018 AFA_RS01195 6c4ebaeb38b53bb507e71baef8b3352b 441 Gene3D G3DSA:3.20.20.70 20 231 0.017 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01195 6c4ebaeb38b53bb507e71baef8b3352b 441 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 39 214 3.5E-51 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 AFA_RS01195 6c4ebaeb38b53bb507e71baef8b3352b 441 SUPERFAMILY SSF53756 60 421 4.77E-10 T 28-03-2018 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 3.0E-20 T 28-03-2018 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 Gene3D G3DSA:1.10.1900.20 55 116 2.8E-27 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 SUPERFAMILY SSF74731 3 117 2.88E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.81 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 Pfam PF00453 Ribosomal protein L20 3 108 4.3E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.7E-47 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.8E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.8E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08725 27d93dde9d4f4a85e02101c34f4c089b 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.8E-39 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF00384 Molybdopterin oxidoreductase 297 728 1.1E-73 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 PIRSF PIRSF036643 18 954 0.0 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF13187 4Fe-4S dicluster domain 169 226 5.9E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SUPERFAMILY SSF54292 22 95 4.22E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SUPERFAMILY SSF53706 241 762 3.8E-195 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:2.20.25.90 236 296 5.0E-17 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:2.40.40.20 794 943 7.6E-34 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF01568 Molydopterin dinucleotide binding domain 813 917 2.1E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 292 4.8E-16 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:3.40.50.740 510 781 1.3E-79 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:3.40.50.740 299 509 5.0E-51 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 143 5.3E-17 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 97 1.5E-20 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SMART SM00929 104 144 1.2E-18 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:3.10.20.30 18 133 1.8E-16 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SUPERFAMILY SSF50692 781 923 2.71E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 Gene3D G3DSA:3.30.70.20 149 231 3.8E-13 T 28-03-2018 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SMART SM00926 240 294 4.8E-17 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 921 6.7E-286 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 AFA_RS03040 66ca3014ddb9004aba002f589662327c 973 SUPERFAMILY SSF54862 97 236 8.37E-38 T 28-03-2018 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 331 8.9E-43 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 543 3.4E-47 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Gene3D G3DSA:3.40.50.1220 192 353 4.0E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 170 3.3E-58 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 SUPERFAMILY SSF52467 188 362 3.1E-61 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Gene3D G3DSA:3.40.50.970 354 566 4.1E-48 T 28-03-2018 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 SUPERFAMILY SSF52518 3 175 2.1E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 SUPERFAMILY SSF52518 373 569 3.69E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 567 1.1E-240 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFA_RS13490 cb1ee2458d93679b53ad7e91507bff82 573 Gene3D G3DSA:3.40.50.970 1 191 2.6E-62 T 28-03-2018 AFA_RS10085 7abefd133e99a61c693e4da98a349222 375 SUPERFAMILY SSF52096 270 346 2.79E-59 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS10085 7abefd133e99a61c693e4da98a349222 375 SUPERFAMILY SSF52096 16 198 2.79E-59 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS10085 7abefd133e99a61c693e4da98a349222 375 Pfam PF16113 Enoyl-CoA hydratase/isomerase 18 360 1.3E-115 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 AFA_RS10085 7abefd133e99a61c693e4da98a349222 375 Gene3D G3DSA:3.90.226.10 2 354 1.8E-74 T 28-03-2018 AFA_RS16545 c2eb60df60507022464829fcbce97dbd 361 Pfam PF13439 Glycosyltransferase Family 4 13 165 1.8E-20 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS16545 c2eb60df60507022464829fcbce97dbd 361 Gene3D G3DSA:3.40.50.2000 1 176 1.7E-25 T 28-03-2018 AFA_RS16545 c2eb60df60507022464829fcbce97dbd 361 Pfam PF00534 Glycosyl transferases group 1 179 340 2.3E-37 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS16545 c2eb60df60507022464829fcbce97dbd 361 Gene3D G3DSA:3.40.50.2000 177 345 1.2E-47 T 28-03-2018 AFA_RS16545 c2eb60df60507022464829fcbce97dbd 361 SUPERFAMILY SSF53756 2 360 2.34E-87 T 28-03-2018 AFA_RS17335 8554bf97324351b35df4fe22ae84f813 301 Pfam PF07859 alpha/beta hydrolase fold 78 200 2.5E-19 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 AFA_RS17335 8554bf97324351b35df4fe22ae84f813 301 Gene3D G3DSA:3.40.50.1820 12 295 1.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS17335 8554bf97324351b35df4fe22ae84f813 301 SUPERFAMILY SSF53474 34 271 6.12E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS00915 9c4ff3fb5a83ecf8ba4775f4b9dd0b80 378 SUPERFAMILY SSF52091 18 71 8.44E-5 T 28-03-2018 IPR002645 STAS domain AFA_RS00915 9c4ff3fb5a83ecf8ba4775f4b9dd0b80 378 Pfam PF02405 Permease MlaE 161 371 6.8E-68 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 AFA_RS00915 9c4ff3fb5a83ecf8ba4775f4b9dd0b80 378 Pfam PF13466 STAS domain 19 77 2.8E-7 T 28-03-2018 IPR002645 STAS domain AFA_RS00915 9c4ff3fb5a83ecf8ba4775f4b9dd0b80 378 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 129 373 6.6E-65 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria AFA_RS09865 b800cec08dda898d93f23c068e639c67 577 TIGRFAM TIGR03764 ICE_PFGI_1_parB: integrating conjugative element, PFGI_1 class, ParB family protein 73 322 3.4E-46 T 28-03-2018 IPR022304 Integrating conjugative element, PFGI-1, ParB AFA_RS09865 b800cec08dda898d93f23c068e639c67 577 Gene3D G3DSA:3.90.1530.10 61 176 1.2E-13 T 28-03-2018 AFA_RS09865 b800cec08dda898d93f23c068e639c67 577 SUPERFAMILY SSF110849 75 191 4.88E-8 T 28-03-2018 IPR003115 ParB/Sulfiredoxin AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 SUPERFAMILY SSF46894 138 240 1.5E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 SUPERFAMILY SSF52172 7 131 3.56E-44 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 SMART SM00862 162 238 3.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 SMART SM00448 10 121 1.3E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 238 1.8E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 Gene3D G3DSA:3.40.50.2300 9 137 2.1E-40 T 28-03-2018 AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 Gene3D G3DSA:1.10.10.10 138 244 1.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13310 e85d3a5b1ba54d81286cd3d0ada8c9d4 244 Pfam PF00072 Response regulator receiver domain 12 122 7.5E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS05655 020373d2dc442a051b27798779aa7166 126 Pfam PF04247 Invasion gene expression up-regulator, SirB 3 121 3.1E-39 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB AFA_RS05655 020373d2dc442a051b27798779aa7166 126 PIRSF PIRSF005610 1 119 5.7E-26 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 7.1E-114 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 Pfam PF02040 Arsenical pump membrane protein 4 423 4.7E-157 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS15405 4e7da152574b5e958ee5977d1a5e34b8 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 426 1.0E-208 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 113 2.8E-14 T 28-03-2018 IPR000014 PAS domain AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 494 4.5E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 Gene3D G3DSA:1.10.287.950 331 530 2.7E-45 T 28-03-2018 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 Pfam PF08447 PAS fold 31 114 1.1E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 2.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 2.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 2.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 2.5E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 SUPERFAMILY SSF55785 20 114 6.11E-27 T 28-03-2018 IPR000014 PAS domain AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 SMART SM00283 279 526 7.5E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 Gene3D G3DSA:1.10.287.950 123 330 1.1E-5 T 28-03-2018 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 Gene3D G3DSA:3.40.50.10600 8 122 9.1E-29 T 28-03-2018 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 SMART SM00091 8 75 1.5E-4 T 28-03-2018 IPR000014 PAS domain AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 SUPERFAMILY SSF58104 254 527 2.75E-68 T 28-03-2018 AFA_RS06085 77c30292ee92abe6f974a91235276a83 576 SMART SM00304 223 278 0.0017 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS03125 4d12f53b8a09e066a776fd4e8cd62153 499 Gene3D G3DSA:1.20.1250.20 3 187 1.3E-13 T 28-03-2018 AFA_RS03125 4d12f53b8a09e066a776fd4e8cd62153 499 SUPERFAMILY SSF103473 8 371 1.44E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS03125 4d12f53b8a09e066a776fd4e8cd62153 499 Gene3D G3DSA:1.20.1250.20 198 376 5.8E-24 T 28-03-2018 AFA_RS03125 4d12f53b8a09e066a776fd4e8cd62153 499 Pfam PF00083 Sugar (and other) transporter 31 158 5.4E-6 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS03125 4d12f53b8a09e066a776fd4e8cd62153 499 Pfam PF07690 Major Facilitator Superfamily 205 374 3.7E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS16570 6728d6666f2e4d53c7dcd51793474073 412 Pfam PF04932 O-Antigen ligase 186 341 7.1E-17 T 28-03-2018 IPR007016 O-antigen ligase-related AFA_RS11735 4d28b365d54d398e1291a71bfd0f10a2 67 Pfam PF05751 FixH 12 43 3.6E-5 T 28-03-2018 IPR008620 Nitrogen fixation protein FixH AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 Pfam PF00394 Multicopper oxidase 215 364 3.1E-16 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 Gene3D G3DSA:2.60.40.420 198 364 2.7E-18 T 28-03-2018 IPR008972 Cupredoxin AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 Gene3D G3DSA:2.60.40.420 40 197 5.7E-27 T 28-03-2018 IPR008972 Cupredoxin AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 Pfam PF07732 Multicopper oxidase 90 198 3.8E-11 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 SUPERFAMILY SSF49503 206 374 2.57E-72 T 28-03-2018 IPR008972 Cupredoxin AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 SUPERFAMILY SSF49503 51 202 2.98E-36 T 28-03-2018 IPR008972 Cupredoxin AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 TIGRFAM TIGR02376 Cu_nitrite_red: nitrite reductase, copper-containing 52 376 8.2E-153 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 75 93 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 120 137 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 162 177 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 137 156 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 180 196 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15925 c109cdc3f67e9a9ee9452d1195443857 381 PRINTS PR00695 Copper containing nitrite reductase signature 102 118 9.0E-53 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 Gene3D G3DSA:3.90.79.10 234 360 5.6E-10 T 28-03-2018 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 SUPERFAMILY SSF48150 10 233 5.65E-69 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 170 4.0E-19 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 Gene3D G3DSA:1.10.340.30 26 124 2.3E-33 T 28-03-2018 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 11 280 5.1E-105 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 SUPERFAMILY SSF55811 229 348 3.83E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 SMART SM00478 44 199 3.3E-40 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 Pfam PF14815 NUDIX domain 244 348 3.0E-22 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS15850 ca7d5b22ff9ef351bbd6996fcbe412bd 363 Gene3D G3DSA:1.10.1670.10 125 233 3.3E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFA_RS16350 38b2b2b981ad7a254bfaca00f85f4d6d 108 Gene3D G3DSA:3.30.160.100 1 96 3.6E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AFA_RS16350 38b2b2b981ad7a254bfaca00f85f4d6d 108 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 5.5E-27 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AFA_RS16350 38b2b2b981ad7a254bfaca00f85f4d6d 108 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 2.7E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AFA_RS16350 38b2b2b981ad7a254bfaca00f85f4d6d 108 SUPERFAMILY SSF69754 3 101 9.29E-35 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 PIRSF PIRSF005962 2 399 1.4E-135 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 SUPERFAMILY SSF55031 184 297 5.0E-35 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 Gene3D G3DSA:3.40.630.10 214 399 9.1E-29 T 28-03-2018 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 Gene3D G3DSA:3.40.630.10 2 213 5.1E-52 T 28-03-2018 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 Pfam PF07687 Peptidase dimerisation domain 186 281 1.9E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 381 7.4E-114 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 Pfam PF01546 Peptidase family M20/M25/M40 74 356 2.3E-35 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 SUPERFAMILY SSF53187 2 198 5.43E-91 T 28-03-2018 AFA_RS03730 7af171869d984b05cc2d2b80e8afa124 399 SUPERFAMILY SSF53187 299 396 5.43E-91 T 28-03-2018 AFA_RS07670 d259b6157ed03877467e94027d586726 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 134 147 - T 28-03-2018 IPR033135 ClpP, histidine active site AFA_RS07670 d259b6157ed03877467e94027d586726 217 SUPERFAMILY SSF52096 33 216 3.41E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS07670 d259b6157ed03877467e94027d586726 217 Pfam PF00574 Clp protease 35 214 2.7E-86 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFA_RS07670 d259b6157ed03877467e94027d586726 217 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 25 213 1.4E-102 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 25 215 43.853 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 Gene3D G3DSA:3.90.226.10 24 216 1.3E-44 T 28-03-2018 AFA_RS07670 d259b6157ed03877467e94027d586726 217 PRINTS PR00127 Clp protease catalytic subunit P signature 190 209 2.1E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 PRINTS PR00127 Clp protease catalytic subunit P signature 41 56 2.1E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 PRINTS PR00127 Clp protease catalytic subunit P signature 133 152 2.1E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 PRINTS PR00127 Clp protease catalytic subunit P signature 112 129 2.1E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS07670 d259b6157ed03877467e94027d586726 217 PRINTS PR00127 Clp protease catalytic subunit P signature 81 101 2.1E-52 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 Pfam PF02504 Fatty acid synthesis protein 6 325 6.9E-107 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 SUPERFAMILY SSF53659 6 337 9.05E-106 T 28-03-2018 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 Gene3D G3DSA:3.40.718.10 3 339 1.5E-107 T 28-03-2018 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 341 3.8E-107 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 PIRSF PIRSF002465 4 342 1.2E-125 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFA_RS13125 0e338bcc02d1f21fe52853ab66fa44a2 362 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 342 145.451 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 293 4.1E-112 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 Gene3D G3DSA:3.40.190.10 183 261 3.7E-5 T 28-03-2018 AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 Gene3D G3DSA:1.10.10.10 1 86 4.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 SUPERFAMILY SSF46785 6 111 9.47E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 Gene3D G3DSA:3.40.190.10 93 182 4.7E-41 T 28-03-2018 AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 Pfam PF03466 LysR substrate binding domain 88 286 1.4E-17 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12090 c5736ce9ff089582e76aee293c360c59 299 SUPERFAMILY SSF53850 88 286 4.89E-22 T 28-03-2018 AFA_RS13475 7b8ae5a130e40c8574b36c755618bcc1 255 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 23 164 4.0E-35 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AFA_RS13475 7b8ae5a130e40c8574b36c755618bcc1 255 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 81 4.4E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFA_RS13475 7b8ae5a130e40c8574b36c755618bcc1 255 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFA_RS00630 a4b921646dbb1eb2b6077c2accb61a10 425 PIRSF PIRSF006066 1 425 5.7E-163 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00630 a4b921646dbb1eb2b6077c2accb61a10 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 414 2.1E-116 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00630 a4b921646dbb1eb2b6077c2accb61a10 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 418 1.6E-134 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS18165 8482c404b5df01f710cc25135f938a96 172 Gene3D G3DSA:3.10.129.10 6 162 6.0E-19 T 28-03-2018 AFA_RS18165 8482c404b5df01f710cc25135f938a96 172 Pfam PF14539 Domain of unknown function (DUF4442) 27 159 1.9E-16 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 AFA_RS18165 8482c404b5df01f710cc25135f938a96 172 SUPERFAMILY SSF54637 15 162 1.79E-18 T 28-03-2018 IPR029069 HotDog domain AFA_RS11770 048def95fdd3b1591c3c1707c6ed8768 287 SUPERFAMILY SSF56784 180 264 6.59E-5 T 28-03-2018 IPR023214 HAD-like domain AFA_RS11770 048def95fdd3b1591c3c1707c6ed8768 287 Pfam PF00122 E1-E2 ATPase 131 196 4.1E-6 T 28-03-2018 AFA_RS11770 048def95fdd3b1591c3c1707c6ed8768 287 Gene3D G3DSA:1.20.1110.10 116 200 1.2E-5 T 28-03-2018 AFA_RS03340 5d75969942c7fbbf7fbb026408b47d25 138 Gene3D G3DSA:3.10.180.10 2 135 2.0E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS03340 5d75969942c7fbbf7fbb026408b47d25 138 ProSitePatterns PS00934 Glyoxalase I signature 1. 12 33 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS03340 5d75969942c7fbbf7fbb026408b47d25 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 130 7.7E-22 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS03340 5d75969942c7fbbf7fbb026408b47d25 138 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 6 133 4.3E-40 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS03340 5d75969942c7fbbf7fbb026408b47d25 138 SUPERFAMILY SSF54593 9 134 1.75E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 SUPERFAMILY SSF55174 4 82 1.7E-14 T 28-03-2018 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 SMART SM00363 4 61 0.0046 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 SUPERFAMILY SSF55120 65 241 2.72E-37 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 108 238 7.4E-36 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 Pfam PF01479 S4 domain 4 42 4.8E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 Gene3D G3DSA:3.30.70.1560 161 220 1.6E-29 T 28-03-2018 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 Pfam PF00849 RNA pseudouridylate synthase 66 159 2.6E-7 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 Gene3D G3DSA:3.10.290.10 1 59 1.2E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS10520 db83690fd3156af60ee26a3d4fa3f264 244 Gene3D G3DSA:3.30.70.580 60 160 3.1E-14 T 28-03-2018 AFA_RS14110 922a7b0fce681c979540ee157e41411a 357 SUPERFAMILY SSF111369 57 270 1.26E-40 T 28-03-2018 AFA_RS14110 922a7b0fce681c979540ee157e41411a 357 Gene3D G3DSA:2.40.50.100 40 98 2.3E-5 T 28-03-2018 AFA_RS14110 922a7b0fce681c979540ee157e41411a 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 265 5.7E-29 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS14110 922a7b0fce681c979540ee157e41411a 357 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 349 3.4E-79 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS14110 922a7b0fce681c979540ee157e41411a 357 Gene3D G3DSA:1.20.1600.10 99 274 3.3E-18 T 28-03-2018 AFA_RS04160 41312e0b90a8716723a755062ee1daec 198 Gene3D G3DSA:3.30.110.60 5 99 6.5E-20 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFA_RS04160 41312e0b90a8716723a755062ee1daec 198 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 90 2.0E-24 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFA_RS04160 41312e0b90a8716723a755062ee1daec 198 SMART SM01103 6 89 2.1E-33 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFA_RS04160 41312e0b90a8716723a755062ee1daec 198 SUPERFAMILY SSF75471 5 95 1.14E-24 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFA_RS04160 41312e0b90a8716723a755062ee1daec 198 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 3.7E-17 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFA_RS16715 f23b8c9cc0e1b11c0ef2bb27cb0f0500 328 Pfam PF16344 Domain of unknown function (DUF4974) 243 308 2.9E-9 T 28-03-2018 IPR032508 Protein FecR, C-terminal AFA_RS16715 f23b8c9cc0e1b11c0ef2bb27cb0f0500 328 Pfam PF04773 FecR protein 119 211 6.3E-24 T 28-03-2018 IPR006860 FecR protein AFA_RS16715 f23b8c9cc0e1b11c0ef2bb27cb0f0500 328 PIRSF PIRSF018266 4 328 3.1E-79 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS16715 f23b8c9cc0e1b11c0ef2bb27cb0f0500 328 Pfam PF16220 Domain of unknown function (DUF4880) 15 57 3.1E-8 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Gene3D G3DSA:1.20.1220.12 586 721 1.2E-45 T 28-03-2018 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 SUPERFAMILY SSF51645 3 718 1.7E-295 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Gene3D G3DSA:1.10.1860.10 1 88 1.5E-35 T 28-03-2018 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Pfam PF01274 Malate synthase 18 694 2.6E-172 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 718 0.0 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Gene3D G3DSA:3.20.20.360 89 218 4.6E-23 T 28-03-2018 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Gene3D G3DSA:3.20.20.360 220 585 1.8E-97 T 28-03-2018 AFA_RS00580 eecd1c36de36ebdfaa91364e33d27251 721 Hamap MF_00641 Malate synthase G [glcB]. 1 721 385.217 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFA_RS17630 f6284e631f0be92e59734e96a57903c9 419 Pfam PF07399 Putative Na+/H+ antiporter 5 418 3.2E-179 T 28-03-2018 IPR009978 Putative Na+/H+ antiporter AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 Pfam PF12161 HsdM N-terminal domain 13 141 1.8E-15 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 296 302 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 Pfam PF02384 N-6 DNA Methylase 155 460 1.4E-49 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 SUPERFAMILY SSF53335 631 672 1.01E-100 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 SUPERFAMILY SSF53335 12 48 1.01E-100 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 SUPERFAMILY SSF53335 78 485 1.01E-100 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 5.1E-8 T 28-03-2018 AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 176 192 5.1E-8 T 28-03-2018 AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 293 305 5.1E-8 T 28-03-2018 AFA_RS12285 856063309b28f6baa208f3cfe04986dd 675 Gene3D G3DSA:3.40.50.150 177 597 3.2E-36 T 28-03-2018 AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 Gene3D G3DSA:3.40.50.720 1 237 2.4E-56 T 28-03-2018 AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 SUPERFAMILY SSF51735 2 231 2.4E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 Pfam PF00106 short chain dehydrogenase 2 187 1.6E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09125 1cacac2074b23241c99060da2ab7e4a4 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 7.3E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 SUPERFAMILY SSF46785 1 113 1.29E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 Gene3D G3DSA:3.40.190.10 179 269 4.6E-22 T 28-03-2018 AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 Gene3D G3DSA:1.10.10.10 1 87 5.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 SUPERFAMILY SSF53850 90 293 1.13E-39 T 28-03-2018 AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 Pfam PF03466 LysR substrate binding domain 90 293 1.1E-38 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS00560 66228f6324bfafd432f75a7b7ff55212 297 Gene3D G3DSA:3.40.190.10 90 178 2.4E-19 T 28-03-2018 AFA_RS08745 b382cc3c30f60cc39f6269b17f9c04d6 134 SMART SM00422 19 89 1.3E-4 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS08745 b382cc3c30f60cc39f6269b17f9c04d6 134 Pfam PF13411 MerR HTH family regulatory protein 19 85 3.0E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS08745 b382cc3c30f60cc39f6269b17f9c04d6 134 SUPERFAMILY SSF46955 17 123 5.49E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS08745 b382cc3c30f60cc39f6269b17f9c04d6 134 Gene3D G3DSA:1.10.1660.10 6 129 1.5E-25 T 28-03-2018 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 SUPERFAMILY SSF47384 257 321 1.65E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 Gene3D G3DSA:3.30.565.10 332 488 9.5E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 Gene3D G3DSA:1.10.287.130 237 327 1.8E-7 T 28-03-2018 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 SMART SM00388 260 329 2.5E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 5.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 5.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 5.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 5.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 SUPERFAMILY SSF55874 331 480 1.03E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 481 6.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 323 8.6E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS10825 8ed16fb74e12042d3186996ef3a6c017 488 SMART SM00387 374 484 1.7E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16195 e65c815533b21bc313be14a914e033df 160 Pfam PF01467 Cytidylyltransferase-like 31 124 8.3E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFA_RS16195 e65c815533b21bc313be14a914e033df 160 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 25 159 2.8E-58 T 28-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 AFA_RS16195 e65c815533b21bc313be14a914e033df 160 SUPERFAMILY SSF52374 27 157 4.69E-23 T 28-03-2018 AFA_RS16195 e65c815533b21bc313be14a914e033df 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 94 2.9E-14 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFA_RS16195 e65c815533b21bc313be14a914e033df 160 Gene3D G3DSA:3.40.50.620 26 148 3.3E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 Pfam PF03466 LysR substrate binding domain 92 297 1.9E-35 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 Gene3D G3DSA:3.40.190.10 183 266 4.6E-18 T 28-03-2018 AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 SUPERFAMILY SSF53850 93 299 4.16E-37 T 28-03-2018 AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 SUPERFAMILY SSF46785 5 115 1.13E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 Gene3D G3DSA:1.10.10.10 1 87 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09310 6522713b49d80aeb0d234d6b61a268ed 309 Gene3D G3DSA:3.40.190.10 92 182 3.4E-12 T 28-03-2018 AFA_RS17430 d02cb4802268de8e87ad21c04eca5ec3 65 Pfam PF05532 CsbD-like 4 56 5.0E-19 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS17430 d02cb4802268de8e87ad21c04eca5ec3 65 PIRSF PIRSF039008 1 65 9.3E-32 T 28-03-2018 IPR026042 Stress response protein YjbJ AFA_RS17430 d02cb4802268de8e87ad21c04eca5ec3 65 Gene3D G3DSA:1.10.1470.10 1 64 1.2E-19 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS17430 d02cb4802268de8e87ad21c04eca5ec3 65 SUPERFAMILY SSF69047 1 62 9.42E-25 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 Pfam PF00082 Subtilase family 62 354 1.8E-47 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 SMART SM00869 644 913 9.0E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 62 81 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 306 322 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 120 2.4E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 SUPERFAMILY SSF103515 609 922 2.88E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 SUPERFAMILY SSF52743 44 368 4.06E-66 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 111 121 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 392 423 1.7E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 Pfam PF12951 Passenger-associated-transport-repeat 393 422 2.0E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 307 317 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 Gene3D G3DSA:3.40.50.200 30 372 1.2E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 Pfam PF03797 Autotransporter beta-domain 647 903 9.4E-57 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 455 921 1.1E-35 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 AFA_RS16280 0c48ce24fb1456bb4ba719d3297114c3 922 Gene3D G3DSA:2.40.128.130 599 922 7.3E-53 T 28-03-2018 AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 Gene3D G3DSA:3.40.50.620 1 171 9.3E-66 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 Gene3D G3DSA:3.30.1300.10 173 282 3.2E-32 T 28-03-2018 AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 36.572 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 277 1.9E-86 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 SUPERFAMILY SSF52374 2 279 6.26E-93 T 28-03-2018 AFA_RS16095 ae612f93808b452fe274f94e74cebe61 282 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 4.4E-95 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 Gene3D G3DSA:3.40.50.620 1 218 2.5E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 370 4.3E-127 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 Gene3D G3DSA:2.30.30.280 219 291 2.1E-23 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 SUPERFAMILY SSF52402 6 250 3.09E-55 T 28-03-2018 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 371 38.38 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 Pfam PF03054 tRNA methyl transferase 9 370 2.4E-128 T 28-03-2018 AFA_RS12560 50edbc9a2bfa21d4d4e09eeee238049a 371 Gene3D G3DSA:2.40.30.10 293 371 1.4E-25 T 28-03-2018 AFA_RS00320 e78551cb575d73fd6b2bd7624241f006 133 SUPERFAMILY SSF50249 20 107 1.61E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS00320 e78551cb575d73fd6b2bd7624241f006 133 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 21 53 8.1E-13 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFA_RS00320 e78551cb575d73fd6b2bd7624241f006 133 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 57 109 6.2E-7 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 Gene3D G3DSA:3.40.190.10 90 181 2.8E-21 T 28-03-2018 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 Gene3D G3DSA:1.10.10.10 1 83 7.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 SUPERFAMILY SSF46785 13 113 2.18E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 Gene3D G3DSA:3.40.190.10 182 270 2.2E-17 T 28-03-2018 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 64 1.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 Pfam PF03466 LysR substrate binding domain 90 292 2.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS12970 2569a398e6ebcd263ff55fb910132804 316 SUPERFAMILY SSF53850 92 301 1.45E-37 T 28-03-2018 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SUPERFAMILY SSF53098 309 496 1.31E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SMART SM00279 169 204 1.8E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 3.9E-53 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SUPERFAMILY SSF47807 167 283 1.64E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SUPERFAMILY SSF56672 505 905 5.45E-146 T 28-03-2018 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 ProSitePatterns PS00447 DNA polymerase family A signature. 731 750 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:1.20.1060.10 521 634 2.3E-35 T 28-03-2018 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SMART SM00482 664 869 2.1E-109 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Pfam PF00476 DNA polymerase family A 529 902 1.4E-146 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:3.30.420.10 322 520 1.2E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 TIGRFAM TIGR00593 pola: DNA polymerase I 5 905 4.3E-267 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 250 1.5E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SUPERFAMILY SSF88723 1 166 7.85E-57 T 28-03-2018 IPR029060 PIN domain-like AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 756 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 852 865 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 707 720 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 700 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 768 779 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 838 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 790 801 1.4E-65 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SMART SM00475 2 257 3.5E-118 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SMART SM00479 330 497 0.0027 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 SMART SM00474 310 496 5.3E-29 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Pfam PF01612 3'-5' exonuclease 310 495 7.0E-35 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:3.40.50.1010 3 176 3.3E-68 T 28-03-2018 IPR029060 PIN domain-like AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:1.10.150.20 177 239 1.7E-24 T 28-03-2018 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:3.30.70.370 731 905 1.4E-50 T 28-03-2018 AFA_RS05150 43a290b5a1d626c3b3317afa284cf2d8 905 Gene3D G3DSA:3.30.70.370 635 721 5.6E-14 T 28-03-2018 AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 6 356 6.0E-146 T 28-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 SMART SM00382 32 215 7.6E-22 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 Pfam PF00005 ABC transporter 23 165 6.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 SUPERFAMILY SSF50331 241 331 3.29E-7 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 Gene3D G3DSA:3.40.50.300 5 260 3.0E-74 T 28-03-2018 AFA_RS11355 494e524850c3e111bb7b7c9f8c6aa07c 358 SUPERFAMILY SSF52540 8 246 2.03E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 Gene3D G3DSA:3.40.1280.10 80 246 2.8E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 246 42.324 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 Pfam PF00588 SpoU rRNA Methylase family 99 239 4.3E-37 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 SUPERFAMILY SSF75217 90 246 1.96E-47 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 SUPERFAMILY SSF55315 4 75 1.1E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 75 5.8E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 245 6.2E-73 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 SMART SM00967 5 81 1.5E-11 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFA_RS11285 8282a915f417a9110f715ffe130da60b 248 Gene3D G3DSA:3.30.1330.30 2 76 2.0E-13 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 13 278 33.462 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 Pfam PF02634 FdhD/NarQ family 40 276 3.9E-76 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 PIRSF PIRSF015626 7 280 5.7E-80 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 Gene3D G3DSA:3.10.20.10 41 127 4.1E-20 T 28-03-2018 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 Gene3D G3DSA:3.40.140.10 143 282 1.5E-50 T 28-03-2018 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 35 277 4.3E-67 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFA_RS03035 5579d374f599f40cf9282d32a7668786 288 SUPERFAMILY SSF53927 24 276 5.72E-79 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 Gene3D G3DSA:3.40.640.10 40 276 3.9E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 Pfam PF00155 Aminotransferase class I and II 25 352 3.6E-61 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 355 4.8E-93 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 356 55.006 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 SUPERFAMILY SSF53383 4 356 1.5E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 212 221 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 AFA_RS11545 db43363fe2606d023b7e911de9ba1dd0 360 Gene3D G3DSA:3.90.1150.10 277 357 1.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS03560 5195aeb22020342160203aee5f55c380 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 2.3E-103 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 AFA_RS03560 5195aeb22020342160203aee5f55c380 271 Gene3D G3DSA:3.40.50.300 1 255 2.7E-52 T 28-03-2018 AFA_RS03560 5195aeb22020342160203aee5f55c380 271 PIRSF PIRSF003092 1 271 3.4E-90 T 28-03-2018 IPR025501 ATP binding protein MinD AFA_RS03560 5195aeb22020342160203aee5f55c380 271 SUPERFAMILY SSF52540 1 269 2.97E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03560 5195aeb22020342160203aee5f55c380 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 227 8.9E-17 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 21 218 1.0E-32 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 236 489 3.7E-57 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 432 442 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 PIRSF PIRSF017184 20 494 2.8E-107 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Pfam PF03853 YjeF-related protein N-terminus 42 197 1.2E-36 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Gene3D G3DSA:3.40.50.10260 17 234 7.3E-57 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 SUPERFAMILY SSF64153 21 253 2.09E-54 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 SUPERFAMILY SSF53613 228 490 3.9E-64 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 231 492 19.734 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Pfam PF01256 Carbohydrate kinase 255 469 7.5E-53 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Gene3D G3DSA:3.40.1190.20 235 494 2.5E-50 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS15060 0284ed99b61d20caa472567d725cd364 494 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 22 218 21.607 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 Gene3D G3DSA:1.10.10.60 1 78 1.9E-19 T 28-03-2018 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 PIRSF PIRSF002097 1 78 2.8E-26 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 Pfam PF02954 Bacterial regulatory protein, Fis family 38 74 1.5E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 1.1E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 1.1E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS14430 a96539b902b42cdefcf10246ff1e6eee 79 SUPERFAMILY SSF46689 7 77 2.51E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS05160 0b1b73ed903f8920d9c740ed126a5dde 293 Gene3D G3DSA:3.30.2010.10 73 164 2.9E-20 T 28-03-2018 AFA_RS05160 0b1b73ed903f8920d9c740ed126a5dde 293 Pfam PF01435 Peptidase family M48 81 289 5.5E-39 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFA_RS05160 0b1b73ed903f8920d9c740ed126a5dde 293 Hamap MF_00188 Protease HtpX [htpX]. 1 290 24.737 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 9.2E-17 T 28-03-2018 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 Gene3D G3DSA:3.30.70.920 54 151 2.8E-25 T 28-03-2018 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 SMART SM00344 1 110 6.8E-38 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 Gene3D G3DSA:1.10.10.10 1 52 6.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 2.6E-23 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 SUPERFAMILY SSF46785 1 60 1.82E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 SUPERFAMILY SSF54909 63 150 5.23E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.5E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.5E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS15600 2b1b6f6c1cce4adb70ce55deee31033c 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.5E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS04945 092388308b0c54da544579fbbf4c3975 441 SUPERFAMILY SSF51905 358 404 9.06E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04945 092388308b0c54da544579fbbf4c3975 441 SUPERFAMILY SSF51905 37 259 9.06E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS04945 092388308b0c54da544579fbbf4c3975 441 Pfam PF01266 FAD dependent oxidoreductase 38 395 1.3E-40 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS04945 092388308b0c54da544579fbbf4c3975 441 Gene3D G3DSA:3.50.50.60 23 430 6.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02530 a723052dce03c1d3076e5160f0fa65b1 157 Gene3D G3DSA:3.40.140.10 1 154 5.4E-35 T 28-03-2018 AFA_RS02530 a723052dce03c1d3076e5160f0fa65b1 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFA_RS02530 a723052dce03c1d3076e5160f0fa65b1 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 1.3E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFA_RS02530 a723052dce03c1d3076e5160f0fa65b1 157 SUPERFAMILY SSF53927 2 139 5.69E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFA_RS13585 09f3059b20cb50fca475a228dc77b512 298 Pfam PF07848 PaaX-like protein 28 91 9.5E-13 T 28-03-2018 IPR012906 PaaX-like, N-terminal AFA_RS13585 09f3059b20cb50fca475a228dc77b512 298 PIRSF PIRSF020623 4 296 1.1E-66 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 AFA_RS13585 09f3059b20cb50fca475a228dc77b512 298 Pfam PF08223 PaaX-like protein C-terminal domain 187 286 3.6E-26 T 28-03-2018 IPR013225 PaaX-like, C-terminal AFA_RS13585 09f3059b20cb50fca475a228dc77b512 298 Gene3D G3DSA:1.10.10.10 22 105 8.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 Pfam PF07729 FCD domain 103 226 1.9E-18 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 93 4.1E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 SUPERFAMILY SSF46785 34 97 6.82E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 Gene3D G3DSA:1.20.120.530 96 242 6.8E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 Gene3D G3DSA:1.10.10.10 6 95 5.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 SMART SM00345 35 93 4.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 SMART SM00895 103 227 2.3E-16 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS11630 2af81fb69d6720375cc25222d54b7334 251 SUPERFAMILY SSF48008 100 234 5.75E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 SUPERFAMILY SSF51717 3 266 2.22E-72 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 Gene3D G3DSA:3.20.20.20 1 271 1.8E-78 T 28-03-2018 AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 7 22 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 41 54 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 Pfam PF00809 Pterin binding enzyme 8 249 3.6E-71 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS07945 11a14165b9f48e49cb97408b9e6b17f1 271 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 7 263 7.8E-75 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 SUPERFAMILY SSF109998 250 434 3.53E-42 T 28-03-2018 IPR027304 Trigger factor/SurA domain AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 239 1.3E-11 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Gene3D G3DSA:3.30.70.1050 1 119 2.5E-28 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Hamap MF_00303 Trigger factor [tig]. 1 423 19.559 T 28-03-2018 IPR005215 Trigger factor GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 SUPERFAMILY SSF102735 1 128 1.57E-31 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 6.9E-36 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Gene3D G3DSA:1.10.3120.10 213 394 8.8E-41 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 417 8.7E-30 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 TIGRFAM TIGR00115 tig: trigger factor 11 417 1.2E-126 T 28-03-2018 IPR005215 Trigger factor GO:0015031 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 SUPERFAMILY SSF54534 133 249 4.91E-28 T 28-03-2018 AFA_RS07665 28b0ff270ebfc79cd46fcade70b05b50 436 PIRSF PIRSF003095 1 436 1.0E-117 T 28-03-2018 IPR005215 Trigger factor GO:0015031 AFA_RS18035 1037e40c3f67d81ff66e9bb2bea2e1c5 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.999 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid AFA_RS18035 1037e40c3f67d81ff66e9bb2bea2e1c5 101 SUPERFAMILY SSF57716 2 101 4.42E-39 T 28-03-2018 AFA_RS18035 1037e40c3f67d81ff66e9bb2bea2e1c5 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.3E-27 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18035 1037e40c3f67d81ff66e9bb2bea2e1c5 101 Gene3D G3DSA:4.10.830.10 1 101 3.9E-34 T 28-03-2018 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 Gene3D G3DSA:3.40.50.720 1 163 1.5E-16 T 28-03-2018 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 328 48.121 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 Gene3D G3DSA:3.90.25.10 164 330 1.0E-21 T 28-03-2018 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 327 5.4E-127 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 240 1.9E-41 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS11935 75bd2084e8b06c3b0a49e0899303d703 332 SUPERFAMILY SSF51735 2 327 8.0E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 12 278 24.939 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 PIRSF PIRSF000193 11 281 3.4E-69 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 SUPERFAMILY SSF51735 13 171 4.96E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 SUPERFAMILY SSF48179 174 281 2.04E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 14 278 3.6E-75 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 176 278 1.2E-33 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 Gene3D G3DSA:1.10.3730.10 176 283 1.5E-36 T 28-03-2018 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 13 106 1.7E-11 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 234 256 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AFA_RS09390 f6e2a3918f8444d9b1fbfd1fb780307c 283 Gene3D G3DSA:3.40.50.720 10 175 1.5E-29 T 28-03-2018 AFA_RS03605 a88162c3db85367a5b2fa950f8863718 378 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 116 132 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03605 a88162c3db85367a5b2fa950f8863718 378 SUPERFAMILY SSF47240 4 342 8.12E-111 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS03605 a88162c3db85367a5b2fa950f8863718 378 Pfam PF00268 Ribonucleotide reductase, small chain 33 334 3.7E-49 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS03605 a88162c3db85367a5b2fa950f8863718 378 Gene3D G3DSA:1.10.620.20 1 348 1.4E-113 T 28-03-2018 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 SMART SM01390 3 96 1.0E-47 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 SUPERFAMILY SSF55174 3 207 6.67E-67 T 28-03-2018 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Gene3D G3DSA:3.10.290.10 103 145 6.6E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Gene3D G3DSA:1.10.1050.10 146 207 1.7E-15 T 28-03-2018 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Gene3D G3DSA:1.10.1050.10 1 102 7.8E-42 T 28-03-2018 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.222 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 1.7E-30 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 6.5E-76 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 SMART SM00363 97 161 5.8E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS17975 ffc62baf12bae89c32e5231362d61dd3 207 Pfam PF01479 S4 domain 98 144 7.4E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS10735 46ee18cb4f5e9ad8a43ec525f4223204 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 18.115 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFA_RS10735 46ee18cb4f5e9ad8a43ec525f4223204 128 TIGRFAM TIGR00494 crcB: protein CrcB 6 118 1.1E-28 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFA_RS10735 46ee18cb4f5e9ad8a43ec525f4223204 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 2.4E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 440 33.263 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 433 9.0E-121 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 ProSitePatterns PS00885 EPSP synthase signature 2. 350 368 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 Gene3D G3DSA:3.65.10.10 24 236 8.3E-57 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 SUPERFAMILY SSF55205 6 437 1.1E-118 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 439 6.3E-134 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 PIRSF PIRSF000505 6 440 2.2E-136 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 Gene3D G3DSA:3.65.10.10 237 439 1.7E-57 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFA_RS11970 05f5a559ad73d3cd7d9dd433ebba8c05 440 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFA_RS13270 948a8ef89cb806e7590c746382267ec3 87 PIRSF PIRSF003113 2 87 2.8E-23 T 28-03-2018 IPR002634 BolA protein AFA_RS13270 948a8ef89cb806e7590c746382267ec3 87 Gene3D G3DSA:3.30.300.90 12 87 1.2E-20 T 28-03-2018 AFA_RS13270 948a8ef89cb806e7590c746382267ec3 87 SUPERFAMILY SSF82657 5 86 4.97E-21 T 28-03-2018 IPR002634 BolA protein AFA_RS13270 948a8ef89cb806e7590c746382267ec3 87 Pfam PF01722 BolA-like protein 14 86 2.0E-26 T 28-03-2018 IPR002634 BolA protein AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 ProSitePatterns PS01277 Ribonuclease PH signature. 123 135 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 Hamap MF_00564 Ribonuclease PH [rph]. 8 244 47.095 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 Pfam PF03725 3' exoribonuclease family, domain 2 167 230 7.6E-10 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 SUPERFAMILY SSF55666 161 244 2.88E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 9 243 1.5E-114 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 Gene3D G3DSA:3.30.230.70 2 245 4.2E-56 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 SUPERFAMILY SSF54211 9 188 8.1E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS09285 3137111fc386d6189e30c7f3bca9e9ed 245 Pfam PF01138 3' exoribonuclease family, domain 1 17 143 7.8E-20 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFA_RS15440 06898d5d7ce0beb5809657e0196b0b95 409 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 389 3.9E-125 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS15440 06898d5d7ce0beb5809657e0196b0b95 409 Gene3D G3DSA:3.90.1150.10 258 404 3.0E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS15440 06898d5d7ce0beb5809657e0196b0b95 409 SUPERFAMILY SSF53383 27 389 9.18E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS15440 06898d5d7ce0beb5809657e0196b0b95 409 Gene3D G3DSA:3.40.640.10 5 256 1.2E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS15440 06898d5d7ce0beb5809657e0196b0b95 409 PIRSF PIRSF001434 2 392 4.5E-125 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 SUPERFAMILY SSF51735 3 249 1.73E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 Pfam PF00106 short chain dehydrogenase 6 198 5.9E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07345 ef74a9ea3f2446b13d9d90f254a07205 254 Gene3D G3DSA:3.40.50.720 5 251 3.6E-55 T 28-03-2018 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 Gene3D G3DSA:1.10.10.10 1 71 1.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 3.4E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.1E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.1E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 SUPERFAMILY SSF46785 3 71 8.41E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 SMART SM00420 6 58 3.6E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 SUPERFAMILY SSF100950 73 233 3.27E-24 T 28-03-2018 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 SMART SM01134 72 233 5.4E-57 T 28-03-2018 AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 Pfam PF00455 DeoR C terminal sensor domain 74 232 1.7E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain AFA_RS02260 2818f8285679d6008aeab8ca0975232e 256 Gene3D G3DSA:3.40.50.1360 72 253 7.1E-36 T 28-03-2018 AFA_RS04985 eb9d072ebae0dc6a39d6c9d3eff64aaa 543 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 21 540 3.5E-189 T 28-03-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 AFA_RS04985 eb9d072ebae0dc6a39d6c9d3eff64aaa 543 SUPERFAMILY SSF53474 172 474 2.08E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS04985 eb9d072ebae0dc6a39d6c9d3eff64aaa 543 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 47 213 2.4E-62 T 28-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 AFA_RS04985 eb9d072ebae0dc6a39d6c9d3eff64aaa 543 Gene3D G3DSA:3.40.50.1820 159 476 3.8E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 Gene3D G3DSA:1.10.10.10 2 92 2.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 SUPERFAMILY SSF46785 1 112 1.44E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 Gene3D G3DSA:3.40.190.10 93 180 2.2E-22 T 28-03-2018 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 SUPERFAMILY SSF53850 90 294 8.55E-38 T 28-03-2018 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 Gene3D G3DSA:3.40.190.10 181 268 9.3E-13 T 28-03-2018 AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 Pfam PF03466 LysR substrate binding domain 88 294 2.4E-41 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS10995 d441f0dd773469315b59d79fa2c5e637 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08205 d3e60d1e36a42b6ed1dc8bf5ddd3352c 114 SUPERFAMILY SSF69118 6 109 6.15E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS08205 d3e60d1e36a42b6ed1dc8bf5ddd3352c 114 Gene3D G3DSA:1.20.1290.10 1 114 6.1E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS08205 d3e60d1e36a42b6ed1dc8bf5ddd3352c 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 91 2.1E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS08205 d3e60d1e36a42b6ed1dc8bf5ddd3352c 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 107 4.2E-20 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS16000 b2432285b97510dc2b5e6fa799ce51b9 423 PIRSF PIRSF003085 12 423 4.7E-129 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFA_RS16000 b2432285b97510dc2b5e6fa799ce51b9 423 SUPERFAMILY SSF53335 143 420 1.88E-78 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16000 b2432285b97510dc2b5e6fa799ce51b9 423 Gene3D G3DSA:3.40.50.150 130 419 4.9E-67 T 28-03-2018 AFA_RS16000 b2432285b97510dc2b5e6fa799ce51b9 423 Pfam PF02353 Mycolic acid cyclopropane synthetase 137 415 3.8E-90 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 Gene3D G3DSA:2.60.120.10 73 203 8.1E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 SMART SM00530 7 62 1.7E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 SUPERFAMILY SSF47413 2 67 6.7E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 SUPERFAMILY SSF51182 71 181 3.22E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 Gene3D G3DSA:1.10.260.40 7 71 2.4E-18 T 28-03-2018 AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 Pfam PF07883 Cupin domain 112 181 1.8E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS16860 f5cd9fdbbfef3a8bfed6c662f24753d8 207 Pfam PF01381 Helix-turn-helix 8 57 8.6E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 Gene3D G3DSA:3.40.1080.10 18 228 1.0E-55 T 28-03-2018 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 SMART SM00882 21 218 1.0E-62 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 Pfam PF01144 Coenzyme A transferase 22 214 1.5E-36 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 59 67 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 19 220 3.0E-86 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 AFA_RS08255 a4fe389f630f52f1ca13ff150428b90a 232 SUPERFAMILY SSF100950 20 227 4.51E-64 T 28-03-2018 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Gene3D G3DSA:3.30.950.10 344 479 2.2E-37 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 219 430 1.2E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Gene3D G3DSA:3.30.160.110 106 146 7.5E-17 T 28-03-2018 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 6.7E-12 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 2.4E-71 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 299 332 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 218 452 8.5E-89 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Gene3D G3DSA:3.40.1010.10 217 343 1.1E-38 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 4.7E-7 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 223 237 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Hamap MF_01646 Siroheme synthase [cysG]. 1 463 46.662 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Pfam PF13241 Putative NAD(P)-binding 6 115 2.7E-28 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Gene3D G3DSA:3.40.50.720 1 105 4.8E-20 T 28-03-2018 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 PIRSF PIRSF036426 1 469 1.1E-184 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 SUPERFAMILY SSF53790 216 460 3.93E-74 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 SUPERFAMILY SSF75615 114 205 3.14E-21 T 28-03-2018 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 Gene3D G3DSA:1.10.8.210 151 208 9.9E-12 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS18190 92d49dda39586b2a7c48b5112ef1cfa6 484 SUPERFAMILY SSF51735 1 112 1.52E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 Pfam PF14718 Soluble lytic murein transglycosylase L domain 455 514 2.5E-9 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 Pfam PF01464 Transglycosylase SLT domain 533 638 3.5E-21 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 Gene3D G3DSA:1.10.530.10 520 686 1.1E-29 T 28-03-2018 AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 Gene3D G3DSA:1.10.1240.20 451 516 2.5E-19 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 SUPERFAMILY SSF53955 527 686 6.33E-44 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 SUPERFAMILY SSF48435 82 523 6.93E-87 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 AFA_RS02045 e25f27c7233c791800d252c18daf0972 691 Gene3D G3DSA:1.25.20.10 80 435 3.5E-27 T 28-03-2018 AFA_RS18205 98f18f779d606703dac152d861fb9d00 269 Gene3D G3DSA:3.40.50.300 3 229 7.9E-58 T 28-03-2018 AFA_RS18205 98f18f779d606703dac152d861fb9d00 269 SUPERFAMILY SSF52540 17 229 1.82E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18205 98f18f779d606703dac152d861fb9d00 269 SMART SM00382 41 225 1.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS18205 98f18f779d606703dac152d861fb9d00 269 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS18205 98f18f779d606703dac152d861fb9d00 269 Pfam PF00005 ABC transporter 32 174 1.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18275 8e08a8065d02a28145118b425022873b 280 Pfam PF00005 ABC transporter 56 202 2.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18275 8e08a8065d02a28145118b425022873b 280 SUPERFAMILY SSF52540 53 277 1.1E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18275 8e08a8065d02a28145118b425022873b 280 SMART SM00382 63 251 1.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS18275 8e08a8065d02a28145118b425022873b 280 Gene3D G3DSA:3.40.50.300 10 280 1.4E-68 T 28-03-2018 AFA_RS18275 8e08a8065d02a28145118b425022873b 280 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS16175 ee1120821475203fc0f0c20a8f808747 272 SUPERFAMILY SSF53613 2 269 5.46E-75 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS16175 ee1120821475203fc0f0c20a8f808747 272 Gene3D G3DSA:3.40.1190.20 1 272 6.4E-61 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS16175 ee1120821475203fc0f0c20a8f808747 272 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 265 6.8E-90 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS16175 ee1120821475203fc0f0c20a8f808747 272 Pfam PF08543 Phosphomethylpyrimidine kinase 12 263 2.8E-87 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFA_RS10525 0e1726af3d265438ff18a6016371f3a0 191 SUPERFAMILY SSF64288 9 184 1.45E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS10525 0e1726af3d265438ff18a6016371f3a0 191 Gene3D G3DSA:3.40.1410.10 1 185 3.0E-35 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS10525 0e1726af3d265438ff18a6016371f3a0 191 Pfam PF04345 Chorismate lyase 19 186 1.6E-13 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 AFA_RS10525 0e1726af3d265438ff18a6016371f3a0 191 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 9 186 20.135 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 259 3.3E-122 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 Gene3D G3DSA:3.40.50.300 8 254 1.8E-62 T 28-03-2018 AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 SMART SM00382 37 247 4.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 Pfam PF00005 ABC transporter 28 183 2.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04215 dbfc4b43ebcb32ddd7340f03a033fbfd 259 SUPERFAMILY SSF52540 12 244 6.17E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07940 1d1f4e5b632a327a305187f71f552d40 100 Gene3D G3DSA:3.40.120.10 2 84 7.5E-24 T 28-03-2018 AFA_RS07940 1d1f4e5b632a327a305187f71f552d40 100 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 81 1.9E-22 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS07940 1d1f4e5b632a327a305187f71f552d40 100 SUPERFAMILY SSF53738 2 81 3.81E-22 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 406 2.0E-165 T 28-03-2018 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 Gene3D G3DSA:3.60.70.12 8 279 5.8E-103 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 SUPERFAMILY SSF56266 16 405 8.5E-139 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 Pfam PF01960 ArgJ family 22 408 4.5E-142 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 408 3.2E-124 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFA_RS15750 1389f4acae9397b38399f81c8454fb9c 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 155.563 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFA_RS14910 7f27f9b5ac8353e2d1fe2af04c85587b 134 Pfam PF03476 MOSC N-terminal beta barrel domain 37 122 2.0E-7 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel AFA_RS14910 7f27f9b5ac8353e2d1fe2af04c85587b 134 SUPERFAMILY SSF141673 32 130 1.26E-15 T 28-03-2018 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 SUPERFAMILY SSF55103 238 509 1.48E-51 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 SUPERFAMILY SSF56176 4 236 5.61E-58 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Gene3D G3DSA:3.30.465.10 104 237 3.3E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Gene3D G3DSA:1.10.45.10 468 509 2.0E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Pfam PF01565 FAD binding domain 52 192 7.2E-28 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Gene3D G3DSA:3.30.43.10 1 103 1.1E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Gene3D G3DSA:3.40.462.10 238 467 1.6E-78 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain AFA_RS05560 b07f0feddaf3eb491b69c5af120d42bf 515 Pfam PF02913 FAD linked oxidases, C-terminal domain 320 506 1.0E-10 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 Pfam PF01578 Cytochrome C assembly protein 89 295 5.1E-48 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 1.0E-89 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 633 3.9E-124 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 626 639 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.3E-52 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02910 499fd5e33d5ec6664bae516f08914cd7 657 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 636 9.6E-224 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS06515 7e716accc1444f098765fcd39a07fa2b 386 Gene3D G3DSA:3.10.310.10 1 178 1.2E-79 T 28-03-2018 AFA_RS06515 7e716accc1444f098765fcd39a07fa2b 386 SUPERFAMILY SSF54506 2 170 7.53E-65 T 28-03-2018 AFA_RS06515 7e716accc1444f098765fcd39a07fa2b 386 SUPERFAMILY SSF54506 175 381 9.42E-62 T 28-03-2018 AFA_RS06515 7e716accc1444f098765fcd39a07fa2b 386 Pfam PF04303 PrpF protein 4 380 6.0E-114 T 28-03-2018 IPR007400 PrpF protein AFA_RS06515 7e716accc1444f098765fcd39a07fa2b 386 Gene3D G3DSA:3.10.310.10 179 362 2.4E-58 T 28-03-2018 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 44.983 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 SUPERFAMILY SSF89447 2 131 7.12E-38 T 28-03-2018 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 117 5.0E-50 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 Gene3D G3DSA:2.10.260.10 79 124 0.0055 T 28-03-2018 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 Gene3D G3DSA:2.10.260.10 3 47 0.0033 T 28-03-2018 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 131 1.3E-32 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 Pfam PF02381 MraZ protein, putative antitoxin-like 74 136 3.8E-13 T 28-03-2018 IPR020603 MraZ domain AFA_RS03625 e6655dd4084315dc33f1c47e43cc720c 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 67 9.0E-12 T 28-03-2018 IPR020603 MraZ domain AFA_RS13045 5f2d59b050b2e06ba9d391c7dbbbb276 201 Pfam PF13470 PIN domain 9 107 4.7E-11 T 28-03-2018 IPR002716 PIN domain AFA_RS13045 5f2d59b050b2e06ba9d391c7dbbbb276 201 Gene3D G3DSA:3.40.50.1010 3 153 2.0E-5 T 28-03-2018 IPR029060 PIN domain-like AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Gene3D G3DSA:1.10.8.60 366 573 1.5E-40 T 28-03-2018 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 657 675 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 29 75 4.3E-4 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Pfam PF07724 AAA domain (Cdc48 subfamily) 623 788 4.6E-38 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SUPERFAMILY SSF52540 182 571 2.7E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Gene3D G3DSA:1.10.8.60 794 885 4.5E-13 T 28-03-2018 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SUPERFAMILY SSF52540 572 863 5.03E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SUPERFAMILY SSF81923 14 123 4.32E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 672 690 6.1E-31 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 734 748 6.1E-31 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 627 645 6.1E-31 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 701 719 6.1E-31 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 794 865 9.1E-14 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Gene3D G3DSA:1.10.1780.10 2 163 8.4E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 316 328 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Gene3D G3DSA:3.40.50.300 179 364 9.1E-21 T 28-03-2018 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 356 1.1E-8 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SMART SM00382 623 782 3.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SMART SM00382 221 365 4.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 SMART SM01086 794 883 1.9E-12 T 28-03-2018 IPR019489 Clp ATPase, C-terminal AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 878 0.0 T 28-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 AFA_RS09935 d5c05c404b708d4ea5c59674ed57fa97 893 Gene3D G3DSA:3.40.50.300 583 791 1.1E-36 T 28-03-2018 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:2.40.30.10 272 353 1.4E-12 T 28-03-2018 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Pfam PF09106 Elongation factor SelB, winged helix 452 502 4.7E-17 T 28-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 631 6.9E-127 T 28-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Pfam PF03144 Elongation factor Tu domain 2 193 262 1.2E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Pfam PF00009 Elongation factor Tu GTP binding domain 2 146 2.5E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Pfam PF09107 Elongation factor SelB, winged helix 590 630 3.8E-19 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF50447 176 264 1.81E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:1.10.10.10 574 630 1.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:1.10.10.10 440 502 1.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:1.10.10.10 512 571 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF52540 2 194 1.17E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF46785 439 508 9.52E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:3.40.50.300 1 173 1.9E-26 T 28-03-2018 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF46785 578 632 1.66E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF50465 272 368 3.91E-19 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 Gene3D G3DSA:2.40.30.10 175 265 6.6E-22 T 28-03-2018 AFA_RS16850 2e4a94fd69dadd8b2832a12b71b57292 639 SUPERFAMILY SSF46785 510 573 8.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 SMART SM00487 66 440 1.6E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 Pfam PF00271 Helicase conserved C-terminal domain 588 700 1.1E-4 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 Gene3D G3DSA:3.40.50.10810 50 537 2.0E-26 T 28-03-2018 AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 SUPERFAMILY SSF52540 496 738 4.09E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 SUPERFAMILY SSF52540 56 164 5.32E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 SUPERFAMILY SSF52540 335 416 6.71E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09745 047b708234d276dd52bfc596a1704c26 765 Gene3D G3DSA:3.40.50.300 578 737 3.0E-17 T 28-03-2018 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 20.756 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 SUPERFAMILY SSF46604 87 135 3.14E-8 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 3.0E-31 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 Gene3D G3DSA:2.60.15.10 1 89 3.6E-30 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 SUPERFAMILY SSF51344 3 85 9.02E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 128 2.1E-39 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16595 c9f5ba9125505f9e14e7f8fb77d6a80e 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 5.8E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16080 0b182db767bf32baed58a8e192cf5bf1 215 SUPERFAMILY SSF52540 2 196 3.42E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16080 0b182db767bf32baed58a8e192cf5bf1 215 Gene3D G3DSA:3.40.50.300 1 207 9.7E-35 T 28-03-2018 AFA_RS16080 0b182db767bf32baed58a8e192cf5bf1 215 Pfam PF01121 Dephospho-CoA kinase 3 179 2.6E-53 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFA_RS16080 0b182db767bf32baed58a8e192cf5bf1 215 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 194 25.663 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFA_RS16080 0b182db767bf32baed58a8e192cf5bf1 215 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 179 1.6E-42 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 Gene3D G3DSA:1.10.10.60 225 269 5.0E-9 T 28-03-2018 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 SUPERFAMILY SSF51182 27 192 8.3E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 Gene3D G3DSA:2.60.120.10 26 114 1.2E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 Gene3D G3DSA:1.10.10.60 165 223 1.1E-14 T 28-03-2018 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 262 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 SUPERFAMILY SSF46689 221 268 5.38E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 3.1E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 3.1E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 Pfam PF02311 AraC-like ligand binding domain 29 109 1.1E-10 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 Pfam PF12833 Helix-turn-helix domain 190 268 2.9E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS10745 be41233a40d0135b35fed80e2294ffd9 275 SMART SM00342 184 266 2.0E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 SUPERFAMILY SSF103039 51 231 1.18E-18 T 28-03-2018 IPR028976 CheC-like domain AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 3.1E-27 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 3.1E-27 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 3.1E-27 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 3.1E-27 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 SUPERFAMILY SSF101801 251 325 9.68E-11 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 PIRSF PIRSF002888 3 331 2.7E-89 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 2.7E-15 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 6 320 2.4E-96 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 Gene3D G3DSA:2.30.330.10 240 331 9.0E-15 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 Gene3D G3DSA:3.40.1550.10 47 235 1.4E-37 T 28-03-2018 IPR028976 CheC-like domain AFA_RS05925 4d34059087f4f5116bd5fa7a699d9eed 335 Pfam PF02154 Flagellar motor switch protein FliM 39 231 6.4E-69 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFA_RS11860 d737b9208f6a78c379f4b5618a27722f 181 Pfam PF00929 Exonuclease 9 170 5.4E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS11860 d737b9208f6a78c379f4b5618a27722f 181 Gene3D G3DSA:3.30.420.10 2 181 4.0E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS11860 d737b9208f6a78c379f4b5618a27722f 181 SUPERFAMILY SSF53098 3 180 1.96E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS11860 d737b9208f6a78c379f4b5618a27722f 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 42.328 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 AFA_RS11860 d737b9208f6a78c379f4b5618a27722f 181 SMART SM00479 7 180 3.0E-26 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS12360 11c7aa3070f7981c910ab8ea26b95adb 338 Gene3D G3DSA:3.40.50.300 96 306 4.5E-31 T 28-03-2018 AFA_RS12360 11c7aa3070f7981c910ab8ea26b95adb 338 Pfam PF01926 50S ribosome-binding GTPase 87 205 8.1E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS12360 11c7aa3070f7981c910ab8ea26b95adb 338 Gene3D G3DSA:3.40.50.300 2 95 5.1E-5 T 28-03-2018 AFA_RS12360 11c7aa3070f7981c910ab8ea26b95adb 338 SUPERFAMILY SSF52540 64 262 1.85E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05265 1fe3c2984aff6686807117708037ac4f 185 Gene3D G3DSA:3.40.630.30 2 183 3.7E-38 T 28-03-2018 AFA_RS05265 1fe3c2984aff6686807117708037ac4f 185 SUPERFAMILY SSF55729 3 164 4.12E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS05265 1fe3c2984aff6686807117708037ac4f 185 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 2.2E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS11610 842162f78a7145668264f858ea7142a1 86 Gene3D G3DSA:3.30.1320.10 1 79 5.5E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11610 842162f78a7145668264f858ea7142a1 86 Pfam PF00886 Ribosomal protein S16 8 68 3.2E-22 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11610 842162f78a7145668264f858ea7142a1 86 SUPERFAMILY SSF54565 1 78 1.44E-26 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11610 842162f78a7145668264f858ea7142a1 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 21.659 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11610 842162f78a7145668264f858ea7142a1 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 2.3E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 Pfam PF00574 Clp protease 22 191 2.9E-57 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 1.9E-20 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 1.9E-20 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 1.9E-20 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 192 31.119 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 111 124 - T 28-03-2018 IPR033135 ClpP, histidine active site AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 SUPERFAMILY SSF52096 21 194 2.61E-50 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS08125 49773c6922b4a80ff22e4ab2152305c1 200 Gene3D G3DSA:3.90.226.10 4 193 6.2E-37 T 28-03-2018 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 460 6.1E-113 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 530 42.644 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 530 8.1E-213 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 PIRSF PIRSF000414 1 530 8.2E-210 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Pfam PF02142 MGS-like domain 15 129 1.1E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 SUPERFAMILY SSF53927 224 530 3.21E-126 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 SMART SM00851 15 130 1.8E-58 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 SUPERFAMILY SSF52335 3 199 5.76E-63 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Gene3D G3DSA:3.40.140.20 251 376 1.3E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 SMART SM00798 135 462 7.4E-187 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Gene3D G3DSA:3.40.140.20 377 520 3.2E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS14435 d6df3f3b08d59a8d5b9563449870245e 530 Gene3D G3DSA:3.40.50.1380 1 198 5.0E-68 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain AFA_RS11920 043fab6ba40b897972d8c23dc7b09d82 397 SUPERFAMILY SSF53955 80 391 1.33E-70 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS11920 043fab6ba40b897972d8c23dc7b09d82 397 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 86 387 3.4E-96 T 28-03-2018 IPR011757 Lytic transglycosylase MltB AFA_RS11920 043fab6ba40b897972d8c23dc7b09d82 397 Gene3D G3DSA:1.10.530.10 262 393 3.4E-27 T 28-03-2018 AFA_RS11920 043fab6ba40b897972d8c23dc7b09d82 397 Pfam PF13406 Transglycosylase SLT domain 84 384 4.7E-83 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 AFA_RS11920 043fab6ba40b897972d8c23dc7b09d82 397 Gene3D G3DSA:1.10.8.350 145 256 7.9E-30 T 28-03-2018 AFA_RS14670 58e65ddfca301fedb374235d8a69ec67 305 Gene3D G3DSA:1.10.3470.10 1 290 7.0E-38 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS14670 58e65ddfca301fedb374235d8a69ec67 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 277 2.3E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 151 659 7.0E-71 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 128 678 3.2E-167 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF56784 436 676 5.77E-50 T 28-03-2018 IPR023214 HAD-like domain AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF56784 379 398 5.77E-50 T 28-03-2018 IPR023214 HAD-like domain AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF55008 1 56 1.26E-7 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Pfam PF00702 haloacid dehalogenase-like hydrolase 379 589 4.6E-32 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Gene3D G3DSA:3.30.70.100 1 62 3.8E-5 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00941 Cadmium-transporting ATPase signature 109 121 1.5E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00941 Cadmium-transporting ATPase signature 245 261 1.5E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00941 Cadmium-transporting ATPase signature 163 183 1.5E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF81665 129 182 1.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF81665 280 366 1.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 382 388 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 SUPERFAMILY SSF81653 189 279 1.31E-19 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Pfam PF00122 E1-E2 ATPase 179 359 6.5E-47 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 380 394 1.8E-23 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 523 533 1.8E-23 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 594 1.8E-23 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 229 243 1.8E-23 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 611 1.8E-23 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Gene3D G3DSA:1.20.1110.10 541 678 9.5E-25 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Gene3D G3DSA:1.20.1110.10 92 392 1.9E-36 T 28-03-2018 AFA_RS05685 593d945a2e4c800aa8cceed1f8d5b1e1 684 Gene3D G3DSA:3.40.1110.10 393 540 3.8E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 Gene3D G3DSA:3.30.1330.50 1 161 1.6E-70 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 4.6E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 Pfam PF02542 YgbB family 5 158 1.2E-62 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 SUPERFAMILY SSF69765 3 160 5.36E-64 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS13320 a19d282d0cdb09ba64c3946f342cdf89 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 35.413 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFA_RS11540 16bdc38db55ea2979457d561b0206efe 78 Gene3D G3DSA:2.30.30.100 5 74 1.6E-33 T 28-03-2018 AFA_RS11540 16bdc38db55ea2979457d561b0206efe 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 65 5.1E-29 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFA_RS11540 16bdc38db55ea2979457d561b0206efe 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 28.273 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFA_RS11540 16bdc38db55ea2979457d561b0206efe 78 Pfam PF17209 Hfq protein 8 69 4.1E-32 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFA_RS11540 16bdc38db55ea2979457d561b0206efe 78 SUPERFAMILY SSF50182 8 70 4.15E-24 T 28-03-2018 IPR010920 LSM domain AFA_RS13295 f3f95eaf8b843a9704beefa6155997f8 436 Pfam PF07690 Major Facilitator Superfamily 11 349 4.6E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS13295 f3f95eaf8b843a9704beefa6155997f8 436 SUPERFAMILY SSF103473 5 416 1.01E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13295 f3f95eaf8b843a9704beefa6155997f8 436 Gene3D G3DSA:1.20.1250.20 1 214 2.2E-11 T 28-03-2018 AFA_RS13295 f3f95eaf8b843a9704beefa6155997f8 436 Gene3D G3DSA:1.20.1250.20 230 421 3.7E-4 T 28-03-2018 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 6 553 49.605 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 SUPERFAMILY SSF51569 20 328 4.76E-90 T 28-03-2018 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 Pfam PF08502 LeuA allosteric (dimerisation) domain 420 551 3.1E-17 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 SUPERFAMILY SSF89000 386 436 1.14E-15 T 28-03-2018 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 Gene3D G3DSA:3.20.20.70 8 374 8.8E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 SMART SM00917 420 552 4.5E-16 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 Pfam PF00682 HMGL-like 32 309 1.3E-69 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 SUPERFAMILY SSF110921 466 549 1.22E-21 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS08230 7666214f857098b511f7946d740ebc6d 556 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS07900 97f41ccc8b773637e2c4f8e3ed5d93e2 355 Pfam PF01758 Sodium Bile acid symporter family 63 257 3.1E-37 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AFA_RS07900 97f41ccc8b773637e2c4f8e3ed5d93e2 355 PIRSF PIRSF005508 4 354 8.2E-119 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AFA_RS07900 97f41ccc8b773637e2c4f8e3ed5d93e2 355 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 344 7.7E-119 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AFA_RS10810 e1262da750306c6b5ffda25617b7cfbf 143 Gene3D G3DSA:1.20.1290.10 3 142 7.5E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS10810 e1262da750306c6b5ffda25617b7cfbf 143 Pfam PF02627 Carboxymuconolactone decarboxylase family 14 94 5.9E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS10810 e1262da750306c6b5ffda25617b7cfbf 143 SUPERFAMILY SSF69118 10 142 1.65E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS10810 e1262da750306c6b5ffda25617b7cfbf 143 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 77 1.7E-12 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 Pfam PF03466 LysR substrate binding domain 105 284 7.4E-28 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 6.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 6.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 6.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 Gene3D G3DSA:3.40.190.10 102 230 1.2E-15 T 28-03-2018 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 Gene3D G3DSA:1.10.10.10 11 98 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 SUPERFAMILY SSF46785 12 103 2.32E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 SUPERFAMILY SSF53850 105 294 6.52E-27 T 28-03-2018 AFA_RS02540 6b7ac72a6095803baf75011e640ebb32 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 6.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.2E-84 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 1.6E-18 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1364 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 6.8E-77 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Gene3D G3DSA:2.40.50.100 907 1009 2.9E-29 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF00623 RNA polymerase Rpb1, domain 2 396 485 1.9E-26 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 393 5.6E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 1.2E-20 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 SMART SM00663 235 514 9.7E-173 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Gene3D G3DSA:2.40.50.100 1010 1038 0.0018 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Gene3D G3DSA:2.40.40.20 346 488 6.7E-40 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1380 18.727 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Gene3D G3DSA:2.40.50.100 1153 1212 3.5E-12 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 Gene3D G3DSA:2.40.50.100 1039 1124 4.1E-12 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 SUPERFAMILY SSF64484 1133 1362 0.0 T 28-03-2018 AFA_RS18340 8c6cf82e851f33f72a56dd3ad10447ff 1421 SUPERFAMILY SSF64484 16 944 0.0 T 28-03-2018 AFA_RS05225 89124ef587bfc05786fce80115208591 330 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 322 2.6E-103 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AFA_RS05225 89124ef587bfc05786fce80115208591 330 SUPERFAMILY SSF53659 6 328 1.58E-102 T 28-03-2018 AFA_RS05225 89124ef587bfc05786fce80115208591 330 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 325 1.0E-109 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AFA_RS05225 89124ef587bfc05786fce80115208591 330 Gene3D G3DSA:3.40.718.10 1 330 2.3E-121 T 28-03-2018 AFA_RS05225 89124ef587bfc05786fce80115208591 330 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 326 33.723 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AFA_RS17105 88396e201819f4649f27edf9838ffac2 259 PRINTS PR01805 VacJ lipoprotein signature 40 53 8.1E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 AFA_RS17105 88396e201819f4649f27edf9838ffac2 259 PRINTS PR01805 VacJ lipoprotein signature 144 161 8.1E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 AFA_RS17105 88396e201819f4649f27edf9838ffac2 259 PRINTS PR01805 VacJ lipoprotein signature 108 125 8.1E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 AFA_RS17105 88396e201819f4649f27edf9838ffac2 259 PRINTS PR01805 VacJ lipoprotein signature 57 73 8.1E-24 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 AFA_RS17105 88396e201819f4649f27edf9838ffac2 259 Pfam PF04333 MlaA lipoprotein 39 235 8.7E-65 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 AFA_RS16430 698da8e902434c052bfda813ba7a1b2f 136 SUPERFAMILY SSF52821 23 135 5.89E-28 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16430 698da8e902434c052bfda813ba7a1b2f 136 SMART SM00450 37 132 2.9E-20 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16430 698da8e902434c052bfda813ba7a1b2f 136 Gene3D G3DSA:3.40.250.10 27 136 9.5E-26 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS16430 698da8e902434c052bfda813ba7a1b2f 136 Pfam PF00581 Rhodanese-like domain 40 127 5.7E-15 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS01220 0e2d9611889bbfa415e18dfbd21fdd3a 222 SUPERFAMILY SSF53474 13 217 9.55E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01220 0e2d9611889bbfa415e18dfbd21fdd3a 222 Pfam PF03959 Serine hydrolase (FSH1) 116 201 2.2E-4 T 28-03-2018 IPR005645 Serine hydrolase FSH AFA_RS01220 0e2d9611889bbfa415e18dfbd21fdd3a 222 Gene3D G3DSA:3.40.50.1820 4 220 3.2E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13970 d52324b6ce90f5be818b5ffe74c7e740 470 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFA_RS13970 d52324b6ce90f5be818b5ffe74c7e740 470 Pfam PF01425 Amidase 26 449 1.7E-121 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS13970 d52324b6ce90f5be818b5ffe74c7e740 470 SUPERFAMILY SSF75304 4 462 6.15E-147 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS13970 d52324b6ce90f5be818b5ffe74c7e740 470 Gene3D G3DSA:3.90.1300.10 1 469 6.9E-153 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 Gene3D G3DSA:1.10.10.10 72 169 5.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 Pfam PF08281 Sigma-70, region 4 113 163 9.6E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 SUPERFAMILY SSF88946 11 76 1.84E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 SUPERFAMILY SSF88659 96 167 9.16E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 Gene3D G3DSA:1.10.1740.10 7 71 1.1E-14 T 28-03-2018 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 165 2.5E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16160 d090d4c6ed9a03fcfec8cfab7b98442c 170 Pfam PF04542 Sigma-70 region 2 13 77 1.3E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS11665 55f793513cfa383199721475376d7f12 417 SUPERFAMILY SSF54373 275 364 4.71E-15 T 28-03-2018 AFA_RS11665 55f793513cfa383199721475376d7f12 417 SUPERFAMILY SSF51905 1 54 1.11E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11665 55f793513cfa383199721475376d7f12 417 SUPERFAMILY SSF51905 107 275 1.11E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11665 55f793513cfa383199721475376d7f12 417 SUPERFAMILY SSF51905 365 412 1.11E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11665 55f793513cfa383199721475376d7f12 417 Pfam PF01266 FAD dependent oxidoreductase 2 403 1.8E-64 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS11665 55f793513cfa383199721475376d7f12 417 Gene3D G3DSA:3.50.50.60 1 417 3.7E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS16955 2ac307760e39b38eb389ef8cb79c959d 515 Gene3D G3DSA:3.40.720.10 218 504 2.3E-16 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS16955 2ac307760e39b38eb389ef8cb79c959d 515 SUPERFAMILY SSF53649 276 445 3.27E-15 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS16955 2ac307760e39b38eb389ef8cb79c959d 515 Pfam PF00884 Sulfatase 265 507 8.4E-23 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 SMART SM00917 424 555 5.2E-28 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 8 556 53.177 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 Gene3D G3DSA:3.20.20.70 10 378 3.7E-112 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 7 554 4.0E-243 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 42 58 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 Pfam PF08502 LeuA allosteric (dimerisation) domain 424 553 3.5E-27 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 SUPERFAMILY SSF110921 453 553 1.57E-30 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 SUPERFAMILY SSF51569 24 332 2.56E-100 T 28-03-2018 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 Pfam PF00682 HMGL-like 35 313 7.5E-78 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 245 258 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFA_RS00750 d35da26a498c4c0f1d2f41ee9808c226 566 SUPERFAMILY SSF89000 390 440 3.92E-15 T 28-03-2018 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 Pfam PF13284 Domain of unknown function (DUF4072) 4 48 6.1E-10 T 28-03-2018 IPR025138 Domain of unknown function DUF4072 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 64 276 1.4E-67 T 28-03-2018 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 Gene3D G3DSA:3.40.50.1000 138 279 1.0E-22 T 28-03-2018 IPR023214 HAD-like domain AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 Pfam PF12710 haloacid dehalogenase-like hydrolase 77 244 1.8E-20 T 28-03-2018 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 Gene3D G3DSA:1.10.150.210 85 137 7.1E-22 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 75 247 2.1E-27 T 28-03-2018 AFA_RS13340 e54a7e3e6437faa555be18c43e2a6c19 283 SUPERFAMILY SSF56784 70 279 4.88E-45 T 28-03-2018 IPR023214 HAD-like domain AFA_RS03405 0c1573ea9c34820fffee22d7e15d3233 259 Gene3D G3DSA:3.40.50.720 1 257 1.8E-27 T 28-03-2018 AFA_RS03405 0c1573ea9c34820fffee22d7e15d3233 259 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 186 2.7E-11 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS03405 0c1573ea9c34820fffee22d7e15d3233 259 SUPERFAMILY SSF51735 2 220 2.92E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 Pfam PF00206 Lyase 18 315 9.8E-60 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 2.6E-16 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 2.6E-16 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 2.6E-16 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 2.6E-16 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 454 1.3E-119 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 Gene3D G3DSA:1.20.200.10 121 393 1.2E-78 T 28-03-2018 AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 Gene3D G3DSA:1.10.40.30 394 448 4.3E-29 T 28-03-2018 AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 Gene3D G3DSA:1.10.275.10 4 120 1.0E-40 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 SUPERFAMILY SSF48557 6 450 6.28E-100 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS12535 f1ad730d77ef9159e807e3c95bddfd5d 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 1.5E-47 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 Pfam PF05191 Adenylate kinase, active site lid 123 158 3.6E-16 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 215 3.2E-73 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 PRINTS PR00094 Adenylate kinase signature 32 46 2.2E-34 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 PRINTS PR00094 Adenylate kinase signature 4 17 2.2E-34 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 PRINTS PR00094 Adenylate kinase signature 156 171 2.2E-34 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 PRINTS PR00094 Adenylate kinase signature 81 97 2.2E-34 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 PRINTS PR00094 Adenylate kinase signature 173 187 2.2E-34 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 Hamap MF_00235 Adenylate kinase [adk]. 1 217 52.341 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 Gene3D G3DSA:3.40.50.300 1 218 2.1E-63 T 28-03-2018 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 Pfam PF00406 Adenylate kinase 5 185 3.4E-57 T 28-03-2018 AFA_RS07350 77f43c9b273d3c9e8c59a91b50266789 218 SUPERFAMILY SSF52540 1 216 4.89E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 52 573 9.2E-119 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 SUPERFAMILY SSF56235 42 580 4.24E-157 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 Pfam PF01019 Gamma-glutamyltranspeptidase 66 576 2.6E-149 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 294 313 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 164 183 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 419 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 484 501 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 164 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 280 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 475 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 423 441 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS03475 d1d82a4865c82a0ea7421a97b1bde999 581 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 73 98 1.5E-63 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 66.891 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 SUPERFAMILY SSF74982 3 127 7.32E-46 T 28-03-2018 IPR023620 Small protein B AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 Pfam PF01668 SmpB protein 3 146 9.8E-55 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 1.0E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 Gene3D G3DSA:2.40.280.10 3 122 1.3E-44 T 28-03-2018 IPR023620 Small protein B AFA_RS10105 7c2a77e11a08cf89d30b1325dbef9953 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 5.8E-50 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 AFA_RS14265 24ca147fbdcb02c2f6d272165b85072e 322 SUPERFAMILY SSF53067 5 132 2.46E-5 T 28-03-2018 AFA_RS14265 24ca147fbdcb02c2f6d272165b85072e 322 Pfam PF12693 GspL periplasmic domain 167 281 3.5E-10 T 28-03-2018 IPR025691 GspL periplasmic domain AFA_RS06630 df93922fe24d2c348da7cbea6b7561e9 454 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 24 441 21.901 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFA_RS06630 df93922fe24d2c348da7cbea6b7561e9 454 Gene3D G3DSA:1.20.1530.10 22 441 1.8E-139 T 28-03-2018 IPR023171 Na/H antiporter domain AFA_RS06630 df93922fe24d2c348da7cbea6b7561e9 454 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 28 434 4.4E-116 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFA_RS06630 df93922fe24d2c348da7cbea6b7561e9 454 Pfam PF06965 Na+/H+ antiporter 1 26 434 1.5E-135 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFA_RS13660 c33ce249fc786d2949da60bf1bd411c7 326 Pfam PF00482 Type II secretion system (T2SS), protein F 180 308 3.0E-13 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS01305 378486fb2ebb1a73392a5f514db1e994 73 Gene3D G3DSA:3.30.110.40 1 73 1.1E-8 T 28-03-2018 IPR001455 TusA-like domain AFA_RS01305 378486fb2ebb1a73392a5f514db1e994 73 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 7 71 2.3E-15 T 28-03-2018 IPR018720 Domain of unknown function DUF2249 AFA_RS01305 378486fb2ebb1a73392a5f514db1e994 73 SUPERFAMILY SSF64307 3 72 5.1E-12 T 28-03-2018 IPR001455 TusA-like domain AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 392 1.8E-90 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 331 409 1.2E-21 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 Gene3D G3DSA:2.60.98.20 139 292 1.9E-30 T 28-03-2018 IPR011491 Flagellar hook protein FlgE AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 Pfam PF07559 Flagellar basal body protein FlaE 173 291 3.1E-20 T 28-03-2018 IPR011491 Flagellar hook protein FlgE AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 Pfam PF00460 Flagella basal body rod protein 6 33 2.9E-8 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFA_RS05835 2a63588c6e62cfcd5dd65f5906c54d78 410 SUPERFAMILY SSF117143 73 371 7.98E-71 T 28-03-2018 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 168 188 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 SMART SM00729 164 382 3.8E-58 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 Pfam PF00919 Uncharacterized protein family UPF0004 21 121 4.9E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 Gene3D G3DSA:3.80.30.20 161 399 1.2E-51 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 21 458 8.3E-180 T 28-03-2018 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 20 459 73.585 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 21 455 4.0E-149 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 Pfam PF04055 Radical SAM superfamily 168 343 3.9E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 Pfam PF01938 TRAM domain 397 458 3.3E-17 T 28-03-2018 IPR002792 TRAM domain AFA_RS03220 a7b6895bd6cf5663bac917be16d163ac 466 SUPERFAMILY SSF102114 146 389 2.35E-58 T 28-03-2018 AFA_RS11450 5571dd56ea3523a707aca5640be36c84 252 Gene3D G3DSA:3.20.20.370 4 251 7.4E-106 T 28-03-2018 AFA_RS11450 5571dd56ea3523a707aca5640be36c84 252 Pfam PF03746 LamB/YcsF family 5 242 5.2E-102 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF AFA_RS11450 5571dd56ea3523a707aca5640be36c84 252 SUPERFAMILY SSF88713 4 250 8.15E-100 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS11450 5571dd56ea3523a707aca5640be36c84 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 247 45.603 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF AFA_RS00685 f1531425f4c79be18cc23222a3bb985e 622 PIRSF PIRSF000719 16 609 7.6E-220 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AFA_RS00685 f1531425f4c79be18cc23222a3bb985e 622 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 17 604 43.368 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AFA_RS00685 f1531425f4c79be18cc23222a3bb985e 622 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 23 602 0.0 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AFA_RS00685 f1531425f4c79be18cc23222a3bb985e 622 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 25 600 5.9E-245 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 453 56.937 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Gene3D G3DSA:3.40.1190.10 91 311 7.0E-41 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 385 1.4E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 SUPERFAMILY SSF53623 98 307 6.93E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Gene3D G3DSA:3.40.50.720 1 90 4.4E-11 T 28-03-2018 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Pfam PF01225 Mur ligase family, catalytic domain 2 101 6.8E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 452 1.4E-204 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 SUPERFAMILY SSF53244 309 452 3.27E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Pfam PF08245 Mur ligase middle domain 108 290 2.6E-18 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 Gene3D G3DSA:3.90.190.20 312 454 7.8E-26 T 28-03-2018 AFA_RS15665 58dbc21ed6ba384ca39f756513d1438f 454 SUPERFAMILY SSF51984 1 90 2.88E-20 T 28-03-2018 AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 SUPERFAMILY SSF52540 88 374 7.55E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 SMART SM00487 31 236 7.6E-63 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 Pfam PF00271 Helicase conserved C-terminal domain 247 353 1.7E-28 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 Gene3D G3DSA:3.40.50.300 2 236 3.3E-62 T 28-03-2018 AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 167 175 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 Pfam PF00270 DEAD/DEAH box helicase 36 210 9.9E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 Gene3D G3DSA:3.40.50.300 237 389 6.8E-46 T 28-03-2018 AFA_RS14375 87e64cca902ac81d33c6691c273e91af 455 SMART SM00490 272 353 3.3E-32 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 SUPERFAMILY SSF53850 97 292 8.69E-20 T 28-03-2018 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 SUPERFAMILY SSF46785 6 112 2.73E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 Gene3D G3DSA:3.40.190.10 89 177 9.2E-7 T 28-03-2018 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 6.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 Pfam PF03466 LysR substrate binding domain 96 279 2.5E-18 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 Gene3D G3DSA:1.10.10.10 1 88 2.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05475 77a5a6adc25dd5afe32457d64b047a53 310 Gene3D G3DSA:3.40.190.10 178 264 1.7E-9 T 28-03-2018 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 421 3.5E-204 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 421 1.5E-146 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 PIRSF PIRSF001434 1 424 7.8E-134 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 SUPERFAMILY SSF53383 1 421 3.82E-135 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 Gene3D G3DSA:3.90.1150.10 289 426 1.4E-52 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14920 cb4c28bcf8f76456a1ac583a567ba00d 426 Gene3D G3DSA:3.40.640.10 1 287 4.3E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS08150 d57d19d5a5117e92543ddfbcf5bca29c 344 Pfam PF00891 O-methyltransferase 148 321 3.0E-15 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 AFA_RS08150 d57d19d5a5117e92543ddfbcf5bca29c 344 SUPERFAMILY SSF53335 161 338 2.61E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS08150 d57d19d5a5117e92543ddfbcf5bca29c 344 Gene3D G3DSA:1.10.10.10 22 119 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08150 d57d19d5a5117e92543ddfbcf5bca29c 344 Gene3D G3DSA:3.40.50.150 120 343 5.0E-31 T 28-03-2018 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 350 3.5E-129 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 Gene3D G3DSA:3.20.20.210 2 358 9.0E-104 T 28-03-2018 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 351 1.2E-132 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 SUPERFAMILY SSF51726 5 355 3.66E-115 T 28-03-2018 AFA_RS01740 048ab59b97b6b473379ff73be6a1d2c4 358 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 352 48.539 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFA_RS07180 9ab6b0390a2a0944dd5f91e0244d410f 272 Pfam PF14302 Domain of unknown function (DUF4377) 182 267 5.3E-21 T 28-03-2018 IPR025485 Domain of unknown function DUF4377 AFA_RS07180 9ab6b0390a2a0944dd5f91e0244d410f 272 Pfam PF03724 META domain 41 157 6.9E-16 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 210 28.483 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 PIRSF PIRSF006755 1 228 2.4E-70 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 SUPERFAMILY SSF52540 1 215 3.24E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 Gene3D G3DSA:3.40.50.300 1 219 7.0E-56 T 28-03-2018 AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 175 7.5E-46 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFA_RS04360 c55890449e4d1ea0e6950a36b55bf241 230 Pfam PF13500 AAA domain 3 207 7.3E-40 T 28-03-2018 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Gene3D G3DSA:3.40.50.80 104 217 1.1E-17 T 28-03-2018 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Pfam PF00970 Oxidoreductase FAD-binding domain 8 105 1.6E-4 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 190 198 5.9E-13 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 139 148 5.9E-13 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 114 133 5.9E-13 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 39 51 5.9E-13 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 29 39 5.9E-13 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Gene3D G3DSA:2.40.30.10 1 103 3.4E-16 T 28-03-2018 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Pfam PF00175 Oxidoreductase NAD-binding domain 115 202 3.3E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 312 6.0E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 SUPERFAMILY SSF52343 101 226 1.18E-24 T 28-03-2018 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 SUPERFAMILY SSF63380 2 103 7.81E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 Gene3D G3DSA:3.10.20.30 218 321 1.3E-18 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS03300 0ed25406b93e1075b2530014b30aa5bf 321 SUPERFAMILY SSF54292 220 319 5.77E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS10355 7e0d01b6e78d0e4f4ed3b5f9358f118a 277 Pfam PF12697 Alpha/beta hydrolase family 28 262 1.1E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS10355 7e0d01b6e78d0e4f4ed3b5f9358f118a 277 SUPERFAMILY SSF53474 17 269 5.93E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS10355 7e0d01b6e78d0e4f4ed3b5f9358f118a 277 Gene3D G3DSA:3.40.50.1820 5 269 3.1E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 162 2.1E-46 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 PIRSF PIRSF000103 1 291 3.4E-74 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 Gene3D G3DSA:1.10.1040.10 173 290 1.0E-28 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 SUPERFAMILY SSF51735 1 163 1.09E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 SUPERFAMILY SSF48179 164 284 6.35E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 Gene3D G3DSA:3.40.50.720 1 172 3.4E-30 T 28-03-2018 AFA_RS12760 c7fe53d69e3d84074fa449c97a6031e1 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 282 4.8E-27 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Gene3D G3DSA:3.60.90.10 1 131 2.7E-31 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Pfam PF02675 S-adenosylmethionine decarboxylase 5 122 4.0E-25 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 119 415 34.627 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Gene3D G3DSA:3.40.50.150 185 416 1.8E-44 T 28-03-2018 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Pfam PF01564 Spermine/spermidine synthase domain 187 361 1.7E-45 T 28-03-2018 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 SUPERFAMILY SSF53335 134 413 7.21E-73 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 SUPERFAMILY SSF56276 3 122 2.86E-22 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 208 221 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFA_RS12450 8ae7bb543e73c31e323ba5febac09122 425 Gene3D G3DSA:2.30.140.10 136 184 1.7E-8 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFA_RS01565 6c462b506ac7dedd7e2b7a51f2f122c1 324 Pfam PF04773 FecR protein 118 210 1.1E-9 T 28-03-2018 IPR006860 FecR protein AFA_RS01565 6c462b506ac7dedd7e2b7a51f2f122c1 324 Pfam PF16344 Domain of unknown function (DUF4974) 223 310 4.2E-10 T 28-03-2018 IPR032508 Protein FecR, C-terminal AFA_RS01565 6c462b506ac7dedd7e2b7a51f2f122c1 324 PIRSF PIRSF018266 8 323 2.8E-55 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS01565 6c462b506ac7dedd7e2b7a51f2f122c1 324 Pfam PF16220 Domain of unknown function (DUF4880) 17 58 9.4E-9 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 Gene3D G3DSA:3.40.50.300 169 367 7.1E-18 T 28-03-2018 AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 Pfam PF00448 SRP54-type protein, GTPase domain 174 365 1.4E-31 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 259 3.8E-64 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 SMART SM00382 170 329 9.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 SUPERFAMILY SSF52540 169 352 9.27E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05790 a779b2c68099e7747745592f9039d7b0 782 SMART SM00962 171 366 1.6E-40 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 Gene3D G3DSA:3.40.50.10490 86 261 2.1E-15 T 28-03-2018 AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 78 1.2E-11 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 Pfam PF01380 SIS domain 131 256 5.6E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 SUPERFAMILY SSF53697 106 260 1.45E-16 T 28-03-2018 AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 Gene3D G3DSA:1.10.10.10 1 81 3.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01925 9b662fd6e02d4b47f3fd570804e8e035 286 SUPERFAMILY SSF46689 5 80 5.91E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18605 f1fd0e0ae801d2f757640716713eadb5 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 8.0E-16 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18605 f1fd0e0ae801d2f757640716713eadb5 44 Pfam PF00468 Ribosomal protein L34 1 44 5.9E-23 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18605 f1fd0e0ae801d2f757640716713eadb5 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18605 f1fd0e0ae801d2f757640716713eadb5 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 2.2E-24 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18605 f1fd0e0ae801d2f757640716713eadb5 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.873 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 Gene3D G3DSA:3.40.190.10 176 264 2.8E-15 T 28-03-2018 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 Gene3D G3DSA:3.40.190.10 87 175 1.0E-20 T 28-03-2018 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 SUPERFAMILY SSF53850 89 295 1.76E-35 T 28-03-2018 AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 Pfam PF03466 LysR substrate binding domain 88 293 7.9E-38 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 SUPERFAMILY SSF46785 2 82 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 Gene3D G3DSA:1.10.10.10 1 83 8.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13900 bfdaf71ad9de9d69a1dd13d6e4401450 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.2E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 Gene3D G3DSA:1.10.10.10 2 101 7.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 SMART SM00418 20 99 3.4E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 Pfam PF01022 Bacterial regulatory protein, arsR family 27 74 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 SUPERFAMILY SSF46785 14 102 5.62E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.4E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 1.4E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS08210 55709c15ab58aed680e945834cb09a6f 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.4E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS00715 180682b71f4650af10bc12a749de5c32 247 SUPERFAMILY SSF110997 172 246 2.22E-19 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS00715 180682b71f4650af10bc12a749de5c32 247 Pfam PF05036 Sporulation related domain 172 246 4.7E-18 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS00715 180682b71f4650af10bc12a749de5c32 247 Gene3D G3DSA:3.30.70.1070 168 247 2.8E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS01625 57312262395b4a42cd9b892ee6baf744 212 SMART SM00903 22 175 1.1E-17 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS01625 57312262395b4a42cd9b892ee6baf744 212 Pfam PF01613 Flavin reductase like domain 22 164 1.8E-18 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS01625 57312262395b4a42cd9b892ee6baf744 212 Gene3D G3DSA:2.30.110.10 13 190 9.6E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS01625 57312262395b4a42cd9b892ee6baf744 212 SUPERFAMILY SSF50475 3 190 1.52E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS13540 277e0cb431ac90ff52731fe631491a7c 208 Gene3D G3DSA:2.50.20.10 20 207 9.7E-37 T 28-03-2018 AFA_RS13540 277e0cb431ac90ff52731fe631491a7c 208 SUPERFAMILY SSF89392 26 207 2.35E-41 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFA_RS13540 277e0cb431ac90ff52731fe631491a7c 208 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 35 197 6.5E-39 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like AFA_RS13540 277e0cb431ac90ff52731fe631491a7c 208 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 207 28.139 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AFA_RS13540 277e0cb431ac90ff52731fe631491a7c 208 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 7 117 2.1E-16 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AFA_RS16585 7c6c5fa044fe3439f5cca9c5e3117d76 179 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 2.4E-71 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFA_RS16585 7c6c5fa044fe3439f5cca9c5e3117d76 179 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 174 8.7E-69 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFA_RS16585 7c6c5fa044fe3439f5cca9c5e3117d76 179 SUPERFAMILY SSF51182 1 176 7.61E-69 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS16585 7c6c5fa044fe3439f5cca9c5e3117d76 179 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 169 2.0E-65 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFA_RS16585 7c6c5fa044fe3439f5cca9c5e3117d76 179 Gene3D G3DSA:2.60.120.10 1 177 2.0E-70 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 PIRSF PIRSF003107 2 223 2.7E-65 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 217 2.0E-69 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 Pfam PF01895 PhoU domain 124 209 5.4E-17 T 28-03-2018 IPR026022 PhoU domain AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 Pfam PF01895 PhoU domain 21 107 1.5E-21 T 28-03-2018 IPR026022 PhoU domain AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 Gene3D G3DSA:1.20.58.220 1 115 1.6E-28 T 28-03-2018 AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 SUPERFAMILY SSF109755 7 227 4.19E-69 T 28-03-2018 AFA_RS05340 7dbafa7363fdae677f19e867a6c5c3f3 244 Gene3D G3DSA:1.20.58.220 116 233 1.8E-28 T 28-03-2018 AFA_RS14980 8a0d33425190710b2b6e2bb75e14bfdf 182 Gene3D G3DSA:1.20.58.320 1 82 2.1E-25 T 28-03-2018 AFA_RS14980 8a0d33425190710b2b6e2bb75e14bfdf 182 Gene3D G3DSA:1.25.40.10 83 181 1.5E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14980 8a0d33425190710b2b6e2bb75e14bfdf 182 SUPERFAMILY SSF48452 6 178 1.55E-65 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS14980 8a0d33425190710b2b6e2bb75e14bfdf 182 Pfam PF06041 Bacterial protein of unknown function (DUF924) 11 179 1.0E-56 T 28-03-2018 IPR010323 Protein of unknown function DUF924 AFA_RS02680 7533341b06672764e2c23c1dc7850184 494 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 20 449 3.5E-115 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS02680 7533341b06672764e2c23c1dc7850184 494 Pfam PF00860 Permease family 25 415 1.5E-100 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS02680 7533341b06672764e2c23c1dc7850184 494 TIGRFAM TIGR03173 pbuX: xanthine permease 28 452 8.1E-153 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 5 121 13.257 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 59 73 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 SUPERFAMILY SSF54211 5 107 1.09E-16 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 Gene3D G3DSA:3.30.230.10 1 120 4.7E-23 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 Pfam PF00825 Ribonuclease P 5 109 4.9E-19 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFA_RS18600 5334e7d3808e9d0d1e08fe61a09fd802 121 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 42 95 3.0E-7 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 SUPERFAMILY SSF52021 1 132 1.14E-54 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 262 3.9E-10 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 336 349 3.9E-10 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 223 232 3.9E-10 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 365 45.085 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 Pfam PF00117 Glutamine amidotransferase class-I 184 359 9.8E-44 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 SMART SM01097 1 125 7.7E-84 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 SUPERFAMILY SSF52317 143 364 8.25E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 Gene3D G3DSA:3.50.30.20 1 141 3.3E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 362 2.4E-141 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 Gene3D G3DSA:3.40.50.880 142 366 6.2E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 181 195 8.0E-39 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 267 8.0E-39 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 268 285 8.0E-39 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 220 234 8.0E-39 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 293 304 8.0E-39 T 28-03-2018 AFA_RS04125 3dcc5bf5976a1715e7993f080c39e93e 368 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 124 6.3E-50 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52540 694 829 1.74E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52540 108 162 1.74E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52540 341 643 1.74E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52540 16 73 1.74E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52540 869 904 1.74E-91 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Gene3D G3DSA:3.40.50.300 470 888 1.6E-21 T 28-03-2018 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 SUPERFAMILY SSF52980 966 1128 2.57E-8 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 453 2.7E-45 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Pfam PF12705 PD-(D/E)XK nuclease superfamily 977 1132 2.6E-7 T 28-03-2018 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Pfam PF13361 UvrD-like helicase C-terminal domain 796 889 9.1E-15 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Pfam PF13361 UvrD-like helicase C-terminal domain 468 659 1.3E-9 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Gene3D G3DSA:3.90.320.10 889 1136 7.1E-10 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 AFA_RS04080 1405905fcd88c47808d4cba5b077e916 1141 Gene3D G3DSA:3.40.50.300 3 458 2.6E-44 T 28-03-2018 AFA_RS18595 96ca3afc8d52fd14de757f8a39fe2509 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-15 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS18595 96ca3afc8d52fd14de757f8a39fe2509 79 Pfam PF01809 Haemolytic domain 3 68 1.6E-28 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS18595 96ca3afc8d52fd14de757f8a39fe2509 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 9 75 8.8E-28 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS18595 96ca3afc8d52fd14de757f8a39fe2509 79 SMART SM01234 1 68 2.6E-42 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS18595 96ca3afc8d52fd14de757f8a39fe2509 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.447 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 Gene3D G3DSA:3.90.650.10 173 349 5.7E-61 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 SUPERFAMILY SSF56042 173 344 5.08E-58 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 344 8.0E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 348 46.152 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 338 4.7E-138 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 SUPERFAMILY SSF55326 9 172 7.15E-51 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 166 8.2E-14 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS03910 9eb1f97a9bb7f21456fc69dc0105a9ad 349 Gene3D G3DSA:3.30.1330.10 34 163 1.5E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS00185 dcb4c786f5ea69788e7db8ccf59b37c1 552 SUPERFAMILY SSF161098 304 540 1.31E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00185 dcb4c786f5ea69788e7db8ccf59b37c1 552 Gene3D G3DSA:1.10.3720.10 11 280 2.5E-42 T 28-03-2018 AFA_RS00185 dcb4c786f5ea69788e7db8ccf59b37c1 552 Gene3D G3DSA:1.10.3720.10 294 546 7.7E-23 T 28-03-2018 AFA_RS00185 dcb4c786f5ea69788e7db8ccf59b37c1 552 SUPERFAMILY SSF161098 21 268 3.38E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00185 dcb4c786f5ea69788e7db8ccf59b37c1 552 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 274 2.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS17700 fe6f8b97decdc00bac911fe7eed788bd 146 Gene3D G3DSA:1.10.1660.10 58 130 2.4E-9 T 28-03-2018 AFA_RS17700 fe6f8b97decdc00bac911fe7eed788bd 146 SUPERFAMILY SSF46955 1 120 4.4E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS17700 fe6f8b97decdc00bac911fe7eed788bd 146 SMART SM00422 1 69 1.6E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS17700 fe6f8b97decdc00bac911fe7eed788bd 146 Pfam PF13411 MerR HTH family regulatory protein 1 66 2.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS17700 fe6f8b97decdc00bac911fe7eed788bd 146 Gene3D G3DSA:1.10.1660.10 1 57 4.8E-18 T 28-03-2018 AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 SUPERFAMILY SSF54106 319 364 3.92E-6 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Pfam PF01476 LysM domain 324 353 5.9E-4 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Pfam PF01476 LysM domain 418 460 5.0E-12 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 SUPERFAMILY SSF53955 91 250 2.73E-42 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Gene3D G3DSA:1.10.530.10 19 236 9.5E-35 T 28-03-2018 AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 SUPERFAMILY SSF54106 416 460 8.76E-11 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Pfam PF01464 Transglycosylase SLT domain 103 201 6.0E-24 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 SMART SM00257 320 364 0.067 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 SMART SM00257 417 460 3.9E-13 T 28-03-2018 IPR018392 LysM domain AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 112 140 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Gene3D G3DSA:3.10.350.10 316 397 2.8E-8 T 28-03-2018 AFA_RS15210 7d38e9b51db1394c6d3b9a878c1f67e2 466 Gene3D G3DSA:3.10.350.10 412 464 7.9E-13 T 28-03-2018 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 382 392 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 436 513 3.5E-15 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 SUPERFAMILY SSF51905 25 351 7.95E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 Gene3D G3DSA:3.30.9.10 103 207 1.9E-14 T 28-03-2018 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 Gene3D G3DSA:3.30.9.10 208 350 3.0E-38 T 28-03-2018 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 48 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 54 66 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 99 111 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 25 37 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 377 389 6.8E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 Pfam PF01266 FAD dependent oxidoreductase 26 389 5.5E-59 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS05715 be5af6b33b46e8b8d97b30a858d800b1 532 Gene3D G3DSA:3.50.50.60 5 94 5.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18315 838dd9348d6120df8e41d803cd34c577 363 Gene3D G3DSA:3.10.350.10 33 81 4.4E-9 T 28-03-2018 AFA_RS18315 838dd9348d6120df8e41d803cd34c577 363 SUPERFAMILY SSF54106 32 80 3.01E-6 T 28-03-2018 IPR018392 LysM domain AFA_RS18315 838dd9348d6120df8e41d803cd34c577 363 Pfam PF01476 LysM domain 34 80 1.6E-7 T 28-03-2018 IPR018392 LysM domain AFA_RS18315 838dd9348d6120df8e41d803cd34c577 363 Pfam PF04773 FecR protein 118 219 5.6E-14 T 28-03-2018 IPR006860 FecR protein AFA_RS16620 fe46293c9574fd9b93b2740de2ac9cfd 156 SUPERFAMILY SSF81573 67 121 5.89E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain AFA_RS16620 fe46293c9574fd9b93b2740de2ac9cfd 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 5.8E-39 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 AFA_RS16620 fe46293c9574fd9b93b2740de2ac9cfd 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 11.627 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFA_RS16620 fe46293c9574fd9b93b2740de2ac9cfd 156 Gene3D G3DSA:1.20.5.620 51 122 2.4E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain AFA_RS16620 fe46293c9574fd9b93b2740de2ac9cfd 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 6.3E-28 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFA_RS08790 08330c0290b6b3b4fda6a53f8295c1f7 150 SUPERFAMILY SSF82649 7 144 6.8E-47 T 28-03-2018 AFA_RS08790 08330c0290b6b3b4fda6a53f8295c1f7 150 Pfam PF01592 NifU-like N terminal domain 12 128 2.9E-18 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFA_RS08790 08330c0290b6b3b4fda6a53f8295c1f7 150 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 8 140 4.2E-44 T 28-03-2018 AFA_RS08790 08330c0290b6b3b4fda6a53f8295c1f7 150 Gene3D G3DSA:3.90.1010.10 5 141 4.0E-46 T 28-03-2018 AFA_RS16520 59d30823ddc178b9e4181795fda0db99 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 244 2.9E-60 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 AFA_RS16520 59d30823ddc178b9e4181795fda0db99 268 Gene3D G3DSA:3.20.20.60 1 259 5.2E-49 T 28-03-2018 AFA_RS16520 59d30823ddc178b9e4181795fda0db99 268 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 254 9.1E-116 T 28-03-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 AFA_RS16520 59d30823ddc178b9e4181795fda0db99 268 SUPERFAMILY SSF51621 3 254 3.14E-83 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS15130 18a8c3426ebe643f16b8d4f81b77fde7 274 Gene3D G3DSA:3.40.50.1820 7 267 8.0E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15130 18a8c3426ebe643f16b8d4f81b77fde7 274 Pfam PF00561 alpha/beta hydrolase fold 33 257 2.3E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS15130 18a8c3426ebe643f16b8d4f81b77fde7 274 SUPERFAMILY SSF53474 9 270 7.25E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 502 5.6E-147 T 28-03-2018 IPR004482 Mg chelatase-related protein AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 204 403 1.3E-86 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 SUPERFAMILY SSF52540 203 501 2.4E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 SMART SM00382 223 394 4.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 411 502 1.4E-23 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 151 1.8E-34 T 28-03-2018 AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 Gene3D G3DSA:3.40.50.300 198 441 7.6E-22 T 28-03-2018 AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 Gene3D G3DSA:3.30.230.10 3 197 6.6E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS08715 d0a82e38b6dd4c8e4189eae49bee6a4d 506 SUPERFAMILY SSF54211 11 181 1.06E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS17545 9684e02390976d54bf21344f0d1e6509 260 Pfam PF02104 SURF1 family 23 233 5.2E-29 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 Gene3D G3DSA:1.20.5.1030 67 118 4.7E-19 T 28-03-2018 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 7.7E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 1.2E-8 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 1.2E-8 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 1.2E-8 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 121 11.659 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFA_RS18375 a027fe50009991f25b2846d0e8ccb89a 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 118 4.2E-18 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 Gene3D G3DSA:2.40.50.140 1 123 5.4E-65 T 28-03-2018 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 3.8E-43 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 SUPERFAMILY SSF50249 2 123 2.23E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 3.2E-61 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.108 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 PIRSF PIRSF002133 1 123 1.3E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18305 8b2b49ecfff07789f1064bef73749273 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 1.3E-69 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS16935 a3d432edbeb0babeb1021477a3875351 335 Gene3D G3DSA:3.10.520.10 44 323 1.4E-35 T 28-03-2018 AFA_RS16935 a3d432edbeb0babeb1021477a3875351 335 SUPERFAMILY SSF143631 40 322 2.22E-65 T 28-03-2018 IPR003374 ApbE-like domain AFA_RS16935 a3d432edbeb0babeb1021477a3875351 335 PIRSF PIRSF006268 8 325 9.6E-54 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFA_RS16935 a3d432edbeb0babeb1021477a3875351 335 Pfam PF02424 ApbE family 66 319 7.2E-54 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 AFA_RS11125 251259c99c19c726b2730f017a03e0d1 138 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 17 104 8.6E-21 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AFA_RS11125 251259c99c19c726b2730f017a03e0d1 138 Pfam PF03334 Na+/H+ antiporter subunit 17 97 9.4E-19 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 SUPERFAMILY SSF81464 29 122 5.07E-27 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Gene3D G3DSA:1.10.287.90 30 123 4.1E-26 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 286 361 3.6E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 253 1.9E-36 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Gene3D G3DSA:2.60.40.420 125 258 6.7E-47 T 28-03-2018 IPR008972 Cupredoxin AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 102 122 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 174 195 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 218 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 218 235 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 102 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 124 143 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 236 253 9.3E-37 T 28-03-2018 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Gene3D G3DSA:1.10.760.10 259 369 1.3E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 SUPERFAMILY SSF49503 176 317 8.52E-53 T 28-03-2018 IPR008972 Cupredoxin AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 SUPERFAMILY SSF49503 120 147 8.52E-53 T 28-03-2018 IPR008972 Cupredoxin AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 263 2.9E-58 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 199 247 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 SUPERFAMILY SSF46626 273 373 6.17E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17520 db1a40e4e7f552423e11cf5bc736e42b 386 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 33 113 3.2E-16 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS06005 3838b4497aacd880b1641022980c95e7 83 Gene3D G3DSA:3.40.1620.10 8 63 3.8E-6 T 28-03-2018 AFA_RS06005 3838b4497aacd880b1641022980c95e7 83 SUPERFAMILY SSF143120 10 73 1.57E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFA_RS06005 3838b4497aacd880b1641022980c95e7 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 76 4.0E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 Gene3D G3DSA:3.40.50.170 91 282 9.9E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 Pfam PF00551 Formyl transferase 87 263 3.0E-38 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PIRSF PIRSF036480 1 282 1.2E-110 T 28-03-2018 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 281 47.073 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 SUPERFAMILY SSF55021 4 82 2.29E-17 T 28-03-2018 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 281 1.1E-100 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 87 109 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 109 136 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 233 255 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 255 280 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 3.6E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 SUPERFAMILY SSF53328 87 282 1.22E-61 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS03480 1e7da75474364ea1f0200c6f604be3a4 282 Gene3D G3DSA:3.30.70.260 1 90 4.7E-26 T 28-03-2018 AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 SMART SM00382 34 232 5.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 Pfam PF00005 ABC transporter 25 184 3.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 SUPERFAMILY SSF52540 10 254 5.81E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 PIRSF PIRSF039085 6 259 3.8E-113 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS01060 79904f7e816733f201cf5fc4116e1d69 259 Gene3D G3DSA:3.40.50.300 6 259 1.0E-71 T 28-03-2018 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 SUPERFAMILY SSF88659 200 294 1.01E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Gene3D G3DSA:1.10.10.10 235 297 3.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 90 103 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 264 290 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Pfam PF04542 Sigma-70 region 2 66 135 4.7E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 SUPERFAMILY SSF88946 28 135 4.97E-40 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 28 295 2.8E-121 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 10 296 51.121 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 294 2.7E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Gene3D G3DSA:1.10.601.10 18 135 2.3E-36 T 28-03-2018 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Pfam PF00140 Sigma-70 factor, region 1.2 29 59 1.0E-4 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 PRINTS PR00046 Major sigma-70 factor signature 264 279 2.8E-18 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 PRINTS PR00046 Major sigma-70 factor signature 90 103 2.8E-18 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 PRINTS PR00046 Major sigma-70 factor signature 244 256 2.8E-18 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 PRINTS PR00046 Major sigma-70 factor signature 279 290 2.8E-18 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17590 46ef2694bc4992c40069c9fc1c45e309 298 Pfam PF04545 Sigma-70, region 4 240 291 1.4E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS12995 a3689a519a28d16ed6e2b1a888e807a9 353 Gene3D G3DSA:1.10.3470.10 20 353 2.9E-69 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS12995 a3689a519a28d16ed6e2b1a888e807a9 353 Pfam PF01032 FecCD transport family 34 349 1.2E-83 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 AFA_RS12995 a3689a519a28d16ed6e2b1a888e807a9 353 SUPERFAMILY SSF81345 15 349 3.66E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 Pfam PF14525 AraC-binding-like domain 18 195 1.4E-24 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 6.6E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 6.6E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 Gene3D G3DSA:1.10.10.60 265 325 2.5E-16 T 28-03-2018 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 SMART SM00342 228 313 8.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 309 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 Gene3D G3DSA:1.10.10.60 210 249 1.5E-4 T 28-03-2018 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 SUPERFAMILY SSF46689 273 317 9.86E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS04595 cc2146745c2632c145089e67f5521e7d 327 Pfam PF12833 Helix-turn-helix domain 234 314 5.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11865 c5eeb53742b89f871567fc62f13eafd8 415 Pfam PF01435 Peptidase family M48 205 414 8.8E-42 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFA_RS11865 c5eeb53742b89f871567fc62f13eafd8 415 Gene3D G3DSA:3.30.2010.10 201 283 4.1E-24 T 28-03-2018 AFA_RS11865 c5eeb53742b89f871567fc62f13eafd8 415 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 24 201 6.0E-54 T 28-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 AFA_RS01335 85395ae81d4693a426d9b89101036521 626 SUPERFAMILY SSF51998 34 567 8.85E-156 T 28-03-2018 AFA_RS01335 85395ae81d4693a426d9b89101036521 626 Gene3D G3DSA:3.20.70.20 45 577 1.2E-184 T 28-03-2018 AFA_RS01335 85395ae81d4693a426d9b89101036521 626 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 33 566 5.3E-135 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 AFA_RS01335 85395ae81d4693a426d9b89101036521 626 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 34 566 5.5E-168 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 AFA_RS14805 274fbcbf19f2a1df98d077559db0ebf2 472 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFA_RS14805 274fbcbf19f2a1df98d077559db0ebf2 472 SUPERFAMILY SSF75304 2 458 5.76E-107 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS14805 274fbcbf19f2a1df98d077559db0ebf2 472 Gene3D G3DSA:3.90.1300.10 1 472 3.3E-113 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS14805 274fbcbf19f2a1df98d077559db0ebf2 472 Pfam PF01425 Amidase 29 450 9.1E-93 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS02735 2f2ab802ed34d9b4c3fa156817f93e36 375 Pfam PF13439 Glycosyltransferase Family 4 12 170 3.3E-11 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS02735 2f2ab802ed34d9b4c3fa156817f93e36 375 Gene3D G3DSA:3.40.50.2000 182 349 4.8E-39 T 28-03-2018 AFA_RS02735 2f2ab802ed34d9b4c3fa156817f93e36 375 SUPERFAMILY SSF53756 2 363 3.93E-66 T 28-03-2018 AFA_RS02735 2f2ab802ed34d9b4c3fa156817f93e36 375 Gene3D G3DSA:3.40.50.2000 1 181 1.2E-16 T 28-03-2018 AFA_RS02735 2f2ab802ed34d9b4c3fa156817f93e36 375 Pfam PF00534 Glycosyl transferases group 1 188 340 4.0E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 Pfam PF01202 Shikimate kinase 40 196 4.2E-51 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 PRINTS PR01100 Shikimate kinase family signature 104 113 9.4E-26 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 PRINTS PR01100 Shikimate kinase family signature 86 94 9.4E-26 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 PRINTS PR01100 Shikimate kinase family signature 58 71 9.4E-26 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 PRINTS PR01100 Shikimate kinase family signature 34 49 9.4E-26 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 PRINTS PR01100 Shikimate kinase family signature 125 142 9.4E-26 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 Gene3D G3DSA:3.40.50.300 29 199 4.9E-32 T 28-03-2018 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 ProSitePatterns PS01128 Shikimate kinase signature. 87 112 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 SUPERFAMILY SSF52540 31 195 4.58E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17890 2a5b0d426df632960cb52994f8269ebe 201 Hamap MF_00109 Shikimate kinase [aroK]. 31 197 29.167 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 Gene3D G3DSA:3.40.30.10 1 99 1.0E-20 T 28-03-2018 AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 Pfam PF13417 Glutathione S-transferase, N-terminal domain 16 85 3.7E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 Pfam PF13410 Glutathione S-transferase, C-terminal domain 138 181 3.5E-6 T 28-03-2018 AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 SUPERFAMILY SSF47616 87 204 5.99E-17 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 Gene3D G3DSA:1.20.1050.10 100 223 2.3E-18 T 28-03-2018 AFA_RS00220 f68818ffb6bcb6deec5b7ab3a63ad518 233 SUPERFAMILY SSF52833 8 85 1.84E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 SUPERFAMILY SSF53807 25 112 3.18E-85 T 28-03-2018 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 SUPERFAMILY SSF53807 162 347 3.18E-85 T 28-03-2018 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00691 Adhesin B signature 28 49 1.2E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00691 Adhesin B signature 72 91 1.2E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00691 Adhesin B signature 53 71 1.2E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 Gene3D G3DSA:3.40.50.1980 150 225 2.2E-21 T 28-03-2018 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 Gene3D G3DSA:3.40.50.1980 19 149 1.2E-33 T 28-03-2018 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 345 1.7E-80 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00690 Adhesin family signature 72 89 4.7E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00690 Adhesin family signature 59 72 4.7E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 PRINTS PR00690 Adhesin family signature 28 46 4.7E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFA_RS01990 2cdb5519721ff70bc80352c37031ae3e 348 Gene3D G3DSA:3.40.50.1980 226 347 1.3E-40 T 28-03-2018 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 SUPERFAMILY SSF55973 5 112 5.1E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Gene3D G3DSA:3.30.300.10 138 237 2.4E-43 T 28-03-2018 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 263 271 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 SUPERFAMILY SSF55973 115 236 2.94E-52 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 387 56.878 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 SUPERFAMILY SSF55973 237 385 5.1E-67 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 235 7.9E-46 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 237 375 2.5E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 387 3.0E-183 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 1.0E-40 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Gene3D G3DSA:3.30.300.10 250 387 7.0E-48 T 28-03-2018 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 Gene3D G3DSA:3.30.300.10 13 137 3.2E-44 T 28-03-2018 AFA_RS02020 b026cdfe8db995f4aad69a8f5f9f960c 387 PIRSF PIRSF000497 1 387 3.0E-171 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 Pfam PF13411 MerR HTH family regulatory protein 2 65 3.3E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 SMART SM00422 1 69 9.1E-28 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 Gene3D G3DSA:1.10.1660.10 1 54 2.5E-21 T 28-03-2018 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 Gene3D G3DSA:1.10.1660.10 55 135 5.2E-18 T 28-03-2018 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 SUPERFAMILY SSF46955 1 125 7.69E-34 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS10320 ae35f5f6776598b9cf7ee8097e566607 138 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 457 5.3E-103 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 123 2.0E-37 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 457 32.304 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Gene3D G3DSA:1.20.120.430 285 457 2.4E-32 T 28-03-2018 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 SUPERFAMILY SSF52540 200 374 8.5E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 SUPERFAMILY SSF52540 71 166 8.5E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Pfam PF01926 50S ribosome-binding GTPase 222 335 2.7E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Gene3D G3DSA:3.30.1360.120 1 124 2.9E-43 T 28-03-2018 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 372 4.5E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Gene3D G3DSA:1.20.120.430 125 284 6.0E-29 T 28-03-2018 AFA_RS18495 18c056b9107dbe46670f79852ced4b4c 457 Pfam PF12631 MnmE helical domain 126 454 3.7E-56 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 AFA_RS16050 4719e0219b30003e031104973394dcef 219 Gene3D G3DSA:3.40.50.150 1 213 3.4E-21 T 28-03-2018 AFA_RS16050 4719e0219b30003e031104973394dcef 219 Pfam PF01564 Spermine/spermidine synthase domain 27 140 2.5E-7 T 28-03-2018 AFA_RS16050 4719e0219b30003e031104973394dcef 219 SUPERFAMILY SSF53335 13 195 1.07E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.8E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 251 3.8E-55 T 28-03-2018 AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 Gene3D G3DSA:3.40.50.720 57 262 1.4E-53 T 28-03-2018 AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 Gene3D G3DSA:3.40.50.720 4 56 3.0E-10 T 28-03-2018 AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 SUPERFAMILY SSF51735 10 252 1.13E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS06545 8f5a20fdfef536b30fa818686891d8cb 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 35 105 2.0E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 SUPERFAMILY SSF46626 32 106 1.06E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 Gene3D G3DSA:1.10.760.10 27 107 1.2E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 PRINTS PR00606 Class ID cytochrome C signature 85 95 1.5E-16 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 PRINTS PR00606 Class ID cytochrome C signature 70 83 1.5E-16 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 PRINTS PR00606 Class ID cytochrome C signature 32 45 1.5E-16 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 PRINTS PR00606 Class ID cytochrome C signature 47 60 1.5E-16 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFA_RS09470 d20ffa931a7eb84921f5ceb1e40bc988 112 PRINTS PR00606 Class ID cytochrome C signature 97 107 1.5E-16 T 28-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFA_RS18125 877d97d5bf574c16235667cefdf23744 277 Pfam PF13242 HAD-hyrolase-like 200 246 1.4E-8 T 28-03-2018 AFA_RS18125 877d97d5bf574c16235667cefdf23744 277 SUPERFAMILY SSF56784 29 247 3.17E-41 T 28-03-2018 IPR023214 HAD-like domain AFA_RS18125 877d97d5bf574c16235667cefdf23744 277 Gene3D G3DSA:3.40.50.1000 20 262 1.7E-21 T 28-03-2018 IPR023214 HAD-like domain AFA_RS18125 877d97d5bf574c16235667cefdf23744 277 Pfam PF13344 Haloacid dehalogenase-like hydrolase 30 125 9.9E-16 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFA_RS00540 65c2eedbe719c618d141c3d6ed51dfb6 195 SUPERFAMILY SSF52218 1 172 2.64E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS00540 65c2eedbe719c618d141c3d6ed51dfb6 195 Gene3D G3DSA:3.40.50.360 2 182 1.1E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS00540 65c2eedbe719c618d141c3d6ed51dfb6 195 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 7 177 4.8E-67 T 28-03-2018 IPR019912 FMN reductase, MsuE-like KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 AFA_RS00540 65c2eedbe719c618d141c3d6ed51dfb6 195 Pfam PF03358 NADPH-dependent FMN reductase 6 150 6.3E-30 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS13625 00badae66e0f3ea8df41b2ef9fca7e21 206 Pfam PF13302 Acetyltransferase (GNAT) domain 21 158 1.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS13625 00badae66e0f3ea8df41b2ef9fca7e21 206 Gene3D G3DSA:3.40.630.30 1 201 2.5E-20 T 28-03-2018 AFA_RS13625 00badae66e0f3ea8df41b2ef9fca7e21 206 SUPERFAMILY SSF55729 12 183 5.31E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS01775 cf9fc1d4f91b6769ebe920a744127853 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 231 2.7E-42 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS01775 cf9fc1d4f91b6769ebe920a744127853 247 Gene3D G3DSA:3.90.226.10 1 209 2.2E-56 T 28-03-2018 AFA_RS01775 cf9fc1d4f91b6769ebe920a744127853 247 Gene3D G3DSA:1.10.12.10 210 244 4.0E-10 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS01775 cf9fc1d4f91b6769ebe920a744127853 247 SUPERFAMILY SSF52096 2 244 5.43E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS02435 d444cc9219afdd3548d23eed7533d862 147 Gene3D G3DSA:3.10.350.10 89 147 1.1E-17 T 28-03-2018 AFA_RS02435 d444cc9219afdd3548d23eed7533d862 147 SMART SM00257 94 145 3.2E-10 T 28-03-2018 IPR018392 LysM domain AFA_RS02435 d444cc9219afdd3548d23eed7533d862 147 Pfam PF04972 BON domain 22 86 4.9E-12 T 28-03-2018 IPR007055 BON domain AFA_RS02435 d444cc9219afdd3548d23eed7533d862 147 Pfam PF01476 LysM domain 95 145 7.1E-13 T 28-03-2018 IPR018392 LysM domain AFA_RS02435 d444cc9219afdd3548d23eed7533d862 147 SUPERFAMILY SSF54106 93 145 6.02E-9 T 28-03-2018 IPR018392 LysM domain AFA_RS01555 650e36bceff3baf371e1ee911c7e67b8 189 Pfam PF04657 Putative inner membrane exporter, YdcZ 9 145 4.7E-39 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 SUPERFAMILY SSF51905 2 345 9.18E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 2.2E-8 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 2.2E-8 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.2E-8 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 Gene3D G3DSA:3.50.50.60 142 348 1.9E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 338 1.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 Gene3D G3DSA:3.50.50.60 1 141 1.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.8E-14 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 1.8E-14 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.8E-14 T 28-03-2018 AFA_RS10110 2d21df6d50825be1c55eae77b468cf99 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-14 T 28-03-2018 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 12 230 3.1E-67 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 Pfam PF00902 Sec-independent protein translocase protein (TatC) 14 225 9.6E-65 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 158 186 1.4E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 89 107 1.4E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 10 37 1.4E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 133 1.4E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS17190 d9c73f4dc1852f2d0b8d370247a08503 255 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 244 18.991 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFA_RS12825 88710555d7b237f37aa69ed861d55d8b 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.804 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12825 88710555d7b237f37aa69ed861d55d8b 78 SUPERFAMILY SSF143800 1 77 4.12E-33 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS12825 88710555d7b237f37aa69ed861d55d8b 78 Pfam PF00830 Ribosomal L28 family 3 62 1.7E-30 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS12825 88710555d7b237f37aa69ed861d55d8b 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 9.2E-31 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12825 88710555d7b237f37aa69ed861d55d8b 78 Gene3D G3DSA:2.30.170.40 2 75 8.0E-33 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS07295 80913ad175748ed303ca293a1e9d0e14 562 Pfam PF03814 Potassium-transporting ATPase A subunit 5 554 2.0E-224 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFA_RS07295 80913ad175748ed303ca293a1e9d0e14 562 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 556 32.309 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFA_RS07295 80913ad175748ed303ca293a1e9d0e14 562 PIRSF PIRSF001294 1 558 9.7E-225 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFA_RS07295 80913ad175748ed303ca293a1e9d0e14 562 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 2 554 6.6E-195 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFA_RS08630 52f1d1c286e75223ac0faf08871219b1 150 Pfam PF01957 NfeD-like C-terminal, partner-binding 11 145 4.6E-20 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain AFA_RS08630 52f1d1c286e75223ac0faf08871219b1 150 Gene3D G3DSA:2.40.50.140 76 150 1.9E-12 T 28-03-2018 AFA_RS08630 52f1d1c286e75223ac0faf08871219b1 150 SUPERFAMILY SSF141322 87 146 3.92E-5 T 28-03-2018 AFA_RS02620 cc6813f366c4e051166cfe65ac7c3cbd 195 PRINTS PR00605 Class IC cytochrome C signature 131 153 3.6E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS02620 cc6813f366c4e051166cfe65ac7c3cbd 195 PRINTS PR00605 Class IC cytochrome C signature 78 89 3.6E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS02620 cc6813f366c4e051166cfe65ac7c3cbd 195 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 70 153 1.5E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02620 cc6813f366c4e051166cfe65ac7c3cbd 195 Gene3D G3DSA:1.10.760.10 56 185 1.1E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02620 cc6813f366c4e051166cfe65ac7c3cbd 195 SUPERFAMILY SSF46626 26 163 1.92E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Gene3D G3DSA:3.40.50.740 276 460 5.5E-26 T 28-03-2018 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 820 0.0 T 28-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 733 760 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Gene3D G3DSA:2.40.40.20 643 821 1.8E-34 T 28-03-2018 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 SUPERFAMILY SSF50692 632 662 1.91E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 SUPERFAMILY SSF50692 692 821 1.91E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Gene3D G3DSA:3.40.228.10 1 275 2.2E-73 T 28-03-2018 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Pfam PF01568 Molydopterin dinucleotide binding domain 699 814 1.5E-14 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Pfam PF00384 Molybdopterin oxidoreductase 12 300 1.9E-18 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 SUPERFAMILY SSF53706 1 653 1.16E-233 T 28-03-2018 AFA_RS16825 e7c20fb2ee5adacf8af1a7099032803a 823 Gene3D G3DSA:3.40.228.10 561 642 2.9E-11 T 28-03-2018 AFA_RS04095 76934032772c4facca586c38fb530d12 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 8.9E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS04095 76934032772c4facca586c38fb530d12 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 23.021 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS04095 76934032772c4facca586c38fb530d12 108 SUPERFAMILY SSF82607 10 102 4.05E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS04095 76934032772c4facca586c38fb530d12 108 Gene3D G3DSA:3.30.1310.10 1 108 1.1E-42 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS04095 76934032772c4facca586c38fb530d12 108 PIRSF PIRSF004555 2 108 4.5E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS04095 76934032772c4facca586c38fb530d12 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 2.0E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 193 202 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 234 243 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 149 156 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 302 310 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 PRINTS PR00410 Phenol hydroxylase reductase family signature 209 228 1.0E-33 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 SUPERFAMILY SSF54292 1 88 2.1E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Gene3D G3DSA:2.40.30.10 103 190 1.1E-26 T 28-03-2018 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Gene3D G3DSA:3.10.20.30 1 94 3.2E-24 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 81 3.2E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Pfam PF00970 Oxidoreductase FAD-binding domain 108 198 9.6E-17 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 SUPERFAMILY SSF52343 204 335 1.7E-32 T 28-03-2018 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Gene3D G3DSA:3.40.50.80 191 331 6.1E-22 T 28-03-2018 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 SUPERFAMILY SSF63380 105 199 5.45E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS08535 652a410ae24c4889f978279b3dd250f5 353 Pfam PF00175 Oxidoreductase NAD-binding domain 210 315 2.8E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 70 2.4E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 Gene3D G3DSA:1.20.1050.10 94 197 2.4E-19 T 28-03-2018 AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 Gene3D G3DSA:3.40.30.10 1 93 1.1E-28 T 28-03-2018 AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 SUPERFAMILY SSF47616 74 197 9.05E-22 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 SUPERFAMILY SSF52833 1 80 2.24E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS09425 01b2046a701d1680ea0b776d4f59bb21 204 Pfam PF14497 Glutathione S-transferase, C-terminal domain 112 196 1.1E-5 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS06945 56697be1676a1fbe8b0c8747598ce24b 981 Gene3D G3DSA:1.10.287.950 84 313 8.8E-5 T 28-03-2018 AFA_RS06945 56697be1676a1fbe8b0c8747598ce24b 981 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 166 237 9.6E-12 T 28-03-2018 IPR013491 Caudovirus, tape measure, N-terminal AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 Gene3D G3DSA:3.40.50.2300 1 121 2.1E-35 T 28-03-2018 AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 Gene3D G3DSA:1.10.10.10 122 226 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 Pfam PF00072 Response regulator receiver domain 3 113 2.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 SUPERFAMILY SSF52172 1 166 4.13E-38 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 SMART SM00862 145 219 2.9E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 5.9E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS16760 2cd3d6be5d881a6b05b3677e7ea25a83 227 SMART SM00448 1 112 1.4E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 123 133 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 PIRSF PIRSF005902 1 255 1.7E-82 T 28-03-2018 IPR001130 TatD family GO:0016788 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 Pfam PF01026 TatD related DNase 3 252 1.6E-78 T 28-03-2018 IPR001130 TatD family GO:0016788 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 7.7E-87 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 Gene3D G3DSA:3.20.20.140 1 254 3.1E-84 T 28-03-2018 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 SUPERFAMILY SSF51556 2 252 8.67E-90 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFA_RS10055 67f835b067ced42cf0e54b1ad46481a8 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 SUPERFAMILY SSF53067 4 196 4.66E-51 T 28-03-2018 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 SUPERFAMILY SSF53067 162 391 2.89E-72 T 28-03-2018 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 176 189 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 298 311 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 205 226 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 320 336 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 5 16 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PRINTS PR00471 Acetate kinase family signature 372 384 8.6E-37 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 Gene3D G3DSA:3.30.420.40 4 197 5.2E-54 T 28-03-2018 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 PIRSF PIRSF000722 1 395 1.9E-130 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 Gene3D G3DSA:3.30.420.40 199 395 9.0E-70 T 28-03-2018 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 Pfam PF00871 Acetokinase family 5 385 1.7E-96 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 Hamap MF_00020 Acetate kinase [ackA]. 1 394 143.144 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS14775 ff2c030cfafed01b5bea6ea33acfd751 395 TIGRFAM TIGR00016 ackA: acetate kinase 2 390 5.5E-100 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFA_RS07980 42bd40ac36e73c479cb24d72f686c506 342 PIRSF PIRSF005632 1 342 1.6E-196 T 28-03-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit AFA_RS07980 42bd40ac36e73c479cb24d72f686c506 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 330 4.4E-37 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS07980 42bd40ac36e73c479cb24d72f686c506 342 SUPERFAMILY SSF51726 7 340 1.44E-68 T 28-03-2018 AFA_RS07980 42bd40ac36e73c479cb24d72f686c506 342 Gene3D G3DSA:3.20.20.210 1 342 8.6E-87 T 28-03-2018 AFA_RS08635 e2ee665b10bc3e177e90a6c838caa5c5 252 Pfam PF13649 Methyltransferase domain 41 136 1.3E-9 T 28-03-2018 AFA_RS08635 e2ee665b10bc3e177e90a6c838caa5c5 252 Gene3D G3DSA:3.40.50.150 7 240 1.1E-17 T 28-03-2018 AFA_RS08635 e2ee665b10bc3e177e90a6c838caa5c5 252 SUPERFAMILY SSF53335 20 250 2.96E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS18100 74bc18c1bd8d2a406c78f27d27e42670 722 Gene3D G3DSA:3.40.720.10 139 468 2.4E-23 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS18100 74bc18c1bd8d2a406c78f27d27e42670 722 Pfam PF04185 Phosphoesterase family 61 463 9.1E-102 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 AFA_RS18100 74bc18c1bd8d2a406c78f27d27e42670 722 Pfam PF05506 Domain of unknown function (DUF756) 533 619 9.0E-24 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS18100 74bc18c1bd8d2a406c78f27d27e42670 722 Pfam PF05506 Domain of unknown function (DUF756) 627 705 4.4E-19 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS18100 74bc18c1bd8d2a406c78f27d27e42670 722 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 18 719 6.0E-275 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS02040 3b3aca46702f75946963ec48b61ab1f7 209 SUPERFAMILY SSF100950 11 204 2.93E-37 T 28-03-2018 AFA_RS02040 3b3aca46702f75946963ec48b61ab1f7 209 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 52 198 1.2E-24 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFA_RS02040 3b3aca46702f75946963ec48b61ab1f7 209 Gene3D G3DSA:3.40.50.10420 1 204 6.7E-43 T 28-03-2018 AFA_RS02040 3b3aca46702f75946963ec48b61ab1f7 209 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 51 198 7.0E-35 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 Gene3D G3DSA:3.30.450.20 81 202 2.9E-6 T 28-03-2018 AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 Gene3D G3DSA:3.30.450.20 203 322 5.1E-15 T 28-03-2018 AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 557 8.2E-50 T 28-03-2018 IPR000160 GGDEF domain AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 SMART SM00267 394 559 1.7E-59 T 28-03-2018 IPR000160 GGDEF domain AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 SUPERFAMILY SSF55073 410 557 1.88E-47 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 Pfam PF00990 Diguanylate cyclase, GGDEF domain 407 555 1.8E-43 T 28-03-2018 IPR000160 GGDEF domain AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 Pfam PF02743 Cache domain 80 307 2.9E-15 T 28-03-2018 IPR033479 Double Cache domain 1 AFA_RS16690 d07e3d11f3a2aec2f077a15bc2fd482f 560 Gene3D G3DSA:3.30.70.270 396 559 2.4E-54 T 28-03-2018 AFA_RS06550 98dcd04a8b2de450ec6263e6764be4d3 530 Gene3D G3DSA:3.50.50.60 1 530 4.7E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06550 98dcd04a8b2de450ec6263e6764be4d3 530 Pfam PF01593 Flavin containing amine oxidoreductase 22 321 3.0E-18 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFA_RS06550 98dcd04a8b2de450ec6263e6764be4d3 530 SUPERFAMILY SSF51905 7 340 9.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06550 98dcd04a8b2de450ec6263e6764be4d3 530 SUPERFAMILY SSF51905 497 529 9.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 230 431 2.3E-21 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 SUPERFAMILY SSF74863 38 156 3.53E-30 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Pfam PF13899 Thioredoxin-like 536 610 1.2E-10 T 28-03-2018 AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 SUPERFAMILY SSF52833 521 635 1.84E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Gene3D G3DSA:2.60.40.1250 35 163 5.7E-37 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 12 638 32.174 T 28-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Pfam PF11412 Disulphide bond corrector protein DsbC 40 156 1.5E-30 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AFA_RS17940 71bf57bb226cca4d9a5f8442f36d79ae 641 Gene3D G3DSA:3.40.30.10 510 640 2.1E-16 T 28-03-2018 AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 SUPERFAMILY SSF54523 6 84 2.43E-8 T 28-03-2018 AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 25 1.2E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 2 152 3.7E-17 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 26 7.5E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site AFA_RS14285 d6060dc6589cdc0b2d2c136e9a7209cf 156 Gene3D G3DSA:3.55.40.10 35 156 2.8E-9 T 28-03-2018 AFA_RS00925 0abd23aa8a4c832be71b6a70a6151f0e 305 Gene3D G3DSA:1.10.287.1060 204 278 0.0049 T 28-03-2018 AFA_RS00925 0abd23aa8a4c832be71b6a70a6151f0e 305 Gene3D G3DSA:1.10.287.1060 141 203 0.25 T 28-03-2018 AFA_RS00925 0abd23aa8a4c832be71b6a70a6151f0e 305 Pfam PF02470 MlaD protein 45 115 3.7E-12 T 28-03-2018 IPR003399 Mce/MlaD AFA_RS16290 df2180c22c0006789bb31c8f2624a8b4 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 177 6.7E-67 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFA_RS16290 df2180c22c0006789bb31c8f2624a8b4 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 37.603 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFA_RS16290 df2180c22c0006789bb31c8f2624a8b4 183 Gene3D G3DSA:3.40.50.2020 2 183 2.6E-44 T 28-03-2018 AFA_RS16290 df2180c22c0006789bb31c8f2624a8b4 183 Pfam PF00156 Phosphoribosyl transferase domain 49 158 3.2E-17 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFA_RS16290 df2180c22c0006789bb31c8f2624a8b4 183 SUPERFAMILY SSF53271 10 178 1.7E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 Gene3D G3DSA:3.90.1150.10 5 160 1.3E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 PIRSF PIRSF000521 157 394 9.5E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 PIRSF PIRSF000521 19 170 7.3E-11 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 Gene3D G3DSA:3.90.1150.10 286 396 6.9E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 Pfam PF00202 Aminotransferase class-III 20 391 2.0E-101 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 SUPERFAMILY SSF53383 15 391 2.31E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 Gene3D G3DSA:3.40.640.10 161 285 5.3E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS00460 96ecb3a9db16e65c80f4fbfa5dfc40fb 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 392 41.0 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFA_RS07770 e1697abb9eea50731c1ffa063faf0c66 310 Pfam PF01758 Sodium Bile acid symporter family 42 219 1.7E-42 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AFA_RS06925 40e3d85a1cabd1a2996487f8dfa65e57 247 SUPERFAMILY SSF49373 165 245 2.47E-16 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFA_RS06925 40e3d85a1cabd1a2996487f8dfa65e57 247 Pfam PF02368 Bacterial Ig-like domain (group 2) 165 236 7.9E-18 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 AFA_RS06925 40e3d85a1cabd1a2996487f8dfa65e57 247 Gene3D G3DSA:2.60.40.1080 162 247 1.4E-20 T 28-03-2018 AFA_RS06925 40e3d85a1cabd1a2996487f8dfa65e57 247 SMART SM00635 165 238 1.1E-15 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 Gene3D G3DSA:3.40.50.720 113 283 1.6E-48 T 28-03-2018 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 SUPERFAMILY SSF51735 99 281 4.66E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 Gene3D G3DSA:3.40.50.720 3 112 4.1E-28 T 28-03-2018 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 308 8.2E-23 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 SUPERFAMILY SSF52283 16 134 3.02E-28 T 28-03-2018 AFA_RS07330 a13c3e13a90e9b8683632f591ea187ba 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 280 2.7E-49 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFA_RS06275 b0ea08595d7fd98f8aae7ba5205880d7 472 SMART SM00220 21 282 1.3E-14 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFA_RS06275 b0ea08595d7fd98f8aae7ba5205880d7 472 Pfam PF00069 Protein kinase domain 22 272 6.5E-26 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFA_RS06275 b0ea08595d7fd98f8aae7ba5205880d7 472 Gene3D G3DSA:3.30.200.20 14 100 3.9E-7 T 28-03-2018 AFA_RS06275 b0ea08595d7fd98f8aae7ba5205880d7 472 Gene3D G3DSA:1.10.510.10 101 333 2.8E-27 T 28-03-2018 AFA_RS06275 b0ea08595d7fd98f8aae7ba5205880d7 472 SUPERFAMILY SSF56112 16 272 2.43E-38 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS07475 ecce3f20e0314d233cdbca242c34de9a 229 Pfam PF01988 VIT family 15 222 9.6E-55 T 28-03-2018 IPR008217 Ccc1 family AFA_RS00970 86d635445253f4176cad489709195422 538 Gene3D G3DSA:3.40.50.980 18 189 1.7E-34 T 28-03-2018 AFA_RS00970 86d635445253f4176cad489709195422 538 SUPERFAMILY SSF56801 13 523 1.44E-123 T 28-03-2018 AFA_RS00970 86d635445253f4176cad489709195422 538 Gene3D G3DSA:2.30.38.10 336 420 1.5E-20 T 28-03-2018 AFA_RS00970 86d635445253f4176cad489709195422 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS00970 86d635445253f4176cad489709195422 538 Gene3D G3DSA:3.30.300.30 422 529 9.9E-25 T 28-03-2018 AFA_RS00970 86d635445253f4176cad489709195422 538 Gene3D G3DSA:3.40.50.980 190 335 1.1E-27 T 28-03-2018 AFA_RS00970 86d635445253f4176cad489709195422 538 Pfam PF00501 AMP-binding enzyme 30 427 1.1E-71 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS00970 86d635445253f4176cad489709195422 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 511 1.9E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS00620 b5aad40ef840329485bd55d72b20d0ac 326 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 312 2.8E-82 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS00620 b5aad40ef840329485bd55d72b20d0ac 326 PIRSF PIRSF006470 1 326 3.5E-94 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS00620 b5aad40ef840329485bd55d72b20d0ac 326 Gene3D G3DSA:3.40.190.10 151 220 0.056 T 28-03-2018 AFA_RS00620 b5aad40ef840329485bd55d72b20d0ac 326 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 285 5.9E-67 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS00620 b5aad40ef840329485bd55d72b20d0ac 326 SUPERFAMILY SSF53850 30 291 7.44E-6 T 28-03-2018 AFA_RS04205 9129079553ee4ebde1d50caba1134c3e 312 Gene3D G3DSA:1.10.3720.10 16 310 5.7E-31 T 28-03-2018 AFA_RS04205 9129079553ee4ebde1d50caba1134c3e 312 SUPERFAMILY SSF161098 21 296 1.15E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04205 9129079553ee4ebde1d50caba1134c3e 312 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 12 303 2.3E-91 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFA_RS04205 9129079553ee4ebde1d50caba1134c3e 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 300 1.1E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 326 487 8.0E-48 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 PIRSF PIRSF001394 1 506 4.8E-211 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 Pfam PF05683 Fumarase C-terminus 288 489 1.2E-80 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 8.0E-101 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 282 1.7E-64 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 Gene3D G3DSA:3.20.130.10 315 488 2.9E-64 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFA_RS03865 96236eb5c3f9c7e9ec5e0be3bf716688 506 SUPERFAMILY SSF117457 318 487 3.79E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 15 268 3.3E-110 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 280 126.359 T 28-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 Gene3D G3DSA:1.10.150.240 34 103 2.8E-33 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 Pfam PF13419 Haloacid dehalogenase-like hydrolase 19 214 1.6E-10 T 28-03-2018 IPR023214 HAD-like domain AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 SUPERFAMILY SSF56784 16 267 2.62E-57 T 28-03-2018 IPR023214 HAD-like domain AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 214 1.5E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS15345 15890ce69d3a8a4b51b7908167ff91d5 280 Gene3D G3DSA:3.40.50.1000 104 275 1.8E-22 T 28-03-2018 IPR023214 HAD-like domain AFA_RS11375 29cd70aa7ebe58ef1afb04fd48976752 376 SUPERFAMILY SSF51905 282 297 4.27E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11375 29cd70aa7ebe58ef1afb04fd48976752 376 SUPERFAMILY SSF51905 5 214 4.27E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11375 29cd70aa7ebe58ef1afb04fd48976752 376 Gene3D G3DSA:3.50.50.60 1 373 2.9E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11375 29cd70aa7ebe58ef1afb04fd48976752 376 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 6 369 6.2E-124 T 28-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW AFA_RS11375 29cd70aa7ebe58ef1afb04fd48976752 376 Pfam PF01266 FAD dependent oxidoreductase 7 368 1.3E-33 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SMART SM00487 261 460 4.5E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Gene3D G3DSA:3.40.50.300 458 630 1.4E-28 T 28-03-2018 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Pfam PF00270 DEAD/DEAH box helicase 267 435 8.1E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Gene3D G3DSA:2.40.50.140 47 143 1.8E-8 T 28-03-2018 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 30 663 2.6E-217 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SUPERFAMILY SSF52540 286 338 1.44E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SUPERFAMILY SSF52540 508 647 1.44E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SMART SM00490 505 589 5.0E-21 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SUPERFAMILY SSF52540 174 454 2.6E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 SUPERFAMILY SSF50249 23 170 4.45E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Pfam PF00271 Helicase conserved C-terminal domain 479 588 6.8E-18 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Gene3D G3DSA:3.40.50.300 245 457 3.9E-32 T 28-03-2018 AFA_RS09350 41c5ab09d7d0ef0871128a98f1e5f0bd 693 Pfam PF17191 RecG wedge domain 23 168 6.7E-14 T 28-03-2018 IPR033454 RecG, wedge domain AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 Gene3D G3DSA:3.40.640.10 124 339 4.6E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 SMART SM00345 20 78 2.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 78 6.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 SUPERFAMILY SSF53383 126 453 1.61E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 Pfam PF00155 Aminotransferase class I and II 128 452 1.7E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 SUPERFAMILY SSF46785 12 88 2.86E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 Gene3D G3DSA:3.90.1150.10 340 464 5.8E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14725 91ec89dca96fef4f5154c54dd353a2c0 478 Gene3D G3DSA:1.10.10.10 5 92 4.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06025 c97bf6fdda4a6d71ec6a99a3cd149765 1072 Pfam PF07520 Virulence factor SrfB 1 1069 0.0 T 28-03-2018 IPR009216 Virulence factor SrfB AFA_RS06025 c97bf6fdda4a6d71ec6a99a3cd149765 1072 Gene3D G3DSA:3.30.420.40 249 591 2.0E-7 T 28-03-2018 AFA_RS06025 c97bf6fdda4a6d71ec6a99a3cd149765 1072 PIRSF PIRSF034585 1 1072 0.0 T 28-03-2018 IPR009216 Virulence factor SrfB AFA_RS06025 c97bf6fdda4a6d71ec6a99a3cd149765 1072 Gene3D G3DSA:3.30.420.40 592 843 7.5E-5 T 28-03-2018 AFA_RS08320 3405d6dc1f40f62b58e44803aaaf0dea 476 Gene3D G3DSA:2.60.120.380 36 158 4.2E-7 T 28-03-2018 AFA_RS08320 3405d6dc1f40f62b58e44803aaaf0dea 476 Gene3D G3DSA:2.60.120.380 278 366 0.0095 T 28-03-2018 AFA_RS08320 3405d6dc1f40f62b58e44803aaaf0dea 476 Gene3D G3DSA:2.60.120.380 159 264 8.0E-12 T 28-03-2018 AFA_RS08320 3405d6dc1f40f62b58e44803aaaf0dea 476 Gene3D G3DSA:2.60.120.380 378 476 3.6E-12 T 28-03-2018 AFA_RS12230 18cafcb2d292ba068068e6dea60dfd8d 529 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 116 498 5.3E-100 T 28-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain AFA_RS12230 18cafcb2d292ba068068e6dea60dfd8d 529 SUPERFAMILY SSF52540 116 509 1.01E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12230 18cafcb2d292ba068068e6dea60dfd8d 529 Gene3D G3DSA:3.40.50.300 275 512 2.6E-27 T 28-03-2018 AFA_RS12230 18cafcb2d292ba068068e6dea60dfd8d 529 Gene3D G3DSA:3.40.50.300 79 266 5.6E-17 T 28-03-2018 AFA_RS05525 aa589fc673707259f3af2414fceb4bdc 227 Gene3D G3DSA:3.50.30.40 20 195 1.8E-50 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AFA_RS05525 aa589fc673707259f3af2414fceb4bdc 227 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 5 226 6.3E-127 T 28-03-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 AFA_RS05525 aa589fc673707259f3af2414fceb4bdc 227 Pfam PF03737 Aldolase/RraA 28 174 9.4E-39 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AFA_RS05525 aa589fc673707259f3af2414fceb4bdc 227 SUPERFAMILY SSF89562 25 182 2.09E-47 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 Gene3D G3DSA:1.10.10.60 52 72 3.8E-10 T 28-03-2018 AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 63 2.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 Gene3D G3DSA:1.10.357.10 73 202 1.1E-25 T 28-03-2018 AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 Pfam PF08359 YsiA-like protein, C-terminal region 70 176 1.1E-4 T 28-03-2018 IPR013570 Transcription regulator YsiA, C-terminal AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 SUPERFAMILY SSF46689 6 86 1.59E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 SUPERFAMILY SSF48498 84 199 2.76E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS12340 4ec9e95e19b0de5aba019ec409cf9507 202 Gene3D G3DSA:1.10.10.60 11 51 7.5E-11 T 28-03-2018 AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 Gene3D G3DSA:1.20.1250.20 251 448 5.1E-23 T 28-03-2018 AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 Gene3D G3DSA:1.20.1250.20 20 221 2.3E-37 T 28-03-2018 AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 SUPERFAMILY SSF103473 14 440 3.27E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS05535 209298ae1be1a26aaab0f7045e5f831f 456 Pfam PF07690 Major Facilitator Superfamily 36 326 5.5E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS11660 eb42fd11d1f56b061667e3b1ad4802ce 437 SUPERFAMILY SSF53850 37 429 3.71E-44 T 28-03-2018 AFA_RS11660 eb42fd11d1f56b061667e3b1ad4802ce 437 Gene3D G3DSA:3.40.190.10 37 166 2.8E-13 T 28-03-2018 AFA_RS11660 eb42fd11d1f56b061667e3b1ad4802ce 437 Gene3D G3DSA:3.40.190.10 167 372 2.2E-24 T 28-03-2018 AFA_RS11660 eb42fd11d1f56b061667e3b1ad4802ce 437 Pfam PF13416 Bacterial extracellular solute-binding protein 55 370 1.2E-26 T 28-03-2018 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 SUPERFAMILY SSF53720 13 492 3.14E-172 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 Pfam PF00171 Aldehyde dehydrogenase family 26 489 7.3E-177 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 Gene3D G3DSA:3.40.605.10 1 281 5.4E-103 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS01695 21cd553ddc0127d4f1e4600165daa0d8 496 Gene3D G3DSA:3.40.309.10 282 475 3.8E-76 T 28-03-2018 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 Gene3D G3DSA:3.20.20.70 130 270 7.3E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 SUPERFAMILY SSF51690 107 278 2.28E-42 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 TIGRFAM TIGR01334 modD: modD protein 3 279 1.1E-66 T 28-03-2018 IPR006242 Putative pyrophosphorylase ModD GO:0016763 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 Gene3D G3DSA:3.90.1170.20 5 129 1.2E-24 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 SUPERFAMILY SSF54675 4 106 2.2E-17 T 28-03-2018 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 277 1.7E-34 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 105 3.6E-15 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFA_RS00565 128baa42f2721541d35d4a406c25a309 300 PIRSF PIRSF006250 1 282 6.1E-58 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFA_RS10645 5f989e478d92aa499e49798e4ac7d959 314 Pfam PF00005 ABC transporter 27 169 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS10645 5f989e478d92aa499e49798e4ac7d959 314 Gene3D G3DSA:3.40.50.300 7 253 8.2E-61 T 28-03-2018 AFA_RS10645 5f989e478d92aa499e49798e4ac7d959 314 SUPERFAMILY SSF52540 8 232 1.41E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10645 5f989e478d92aa499e49798e4ac7d959 314 SMART SM00382 36 217 1.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS10645 5f989e478d92aa499e49798e4ac7d959 314 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 Gene3D G3DSA:2.40.50.100 168 210 5.0E-4 T 28-03-2018 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 Gene3D G3DSA:2.40.50.100 66 122 4.1E-19 T 28-03-2018 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 SUPERFAMILY SSF111369 55 303 1.31E-77 T 28-03-2018 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 Gene3D G3DSA:1.10.287.470 123 167 2.2E-10 T 28-03-2018 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 376 4.3E-85 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS10405 e766c8834c07c32da4459bcd452988b7 413 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 296 2.9E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS16265 13b08639bd0f71e4346d0c3583dc268b 164 PIRSF PIRSF004633 4 159 3.3E-23 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain AFA_RS16265 13b08639bd0f71e4346d0c3583dc268b 164 Gene3D G3DSA:2.30.110.10 10 163 6.4E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS16265 13b08639bd0f71e4346d0c3583dc268b 164 SUPERFAMILY SSF50475 2 152 7.44E-30 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS16265 13b08639bd0f71e4346d0c3583dc268b 164 Pfam PF13883 Pyridoxamine 5'-phosphate oxidase 14 146 2.3E-8 T 28-03-2018 AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 4.1E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 SUPERFAMILY SSF52540 4 253 3.63E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 SMART SM00382 33 232 2.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 3.7E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 Pfam PF00005 ABC transporter 24 182 4.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00415 2c4cce25f9b3c38f2914b9f1b3051fc4 324 Gene3D G3DSA:3.40.50.300 1 324 1.7E-78 T 28-03-2018 AFA_RS11530 b7ec0e041d02a45e32e71a03b5b2ffa0 439 Pfam PF12221 Bacterial membrane protein N terminal 8 57 4.8E-13 T 28-03-2018 IPR020980 Menbrane protein HflK, N-terminal AFA_RS11530 b7ec0e041d02a45e32e71a03b5b2ffa0 439 TIGRFAM TIGR01933 hflK: HflK protein 100 375 1.2E-89 T 28-03-2018 IPR010201 HflK GO:0016021 AFA_RS11530 b7ec0e041d02a45e32e71a03b5b2ffa0 439 Pfam PF01145 SPFH domain / Band 7 family 102 288 2.3E-29 T 28-03-2018 IPR001107 Band 7 domain AFA_RS11530 b7ec0e041d02a45e32e71a03b5b2ffa0 439 SMART SM00244 98 273 7.0E-31 T 28-03-2018 IPR001107 Band 7 domain AFA_RS11530 b7ec0e041d02a45e32e71a03b5b2ffa0 439 SUPERFAMILY SSF117892 162 280 2.48E-21 T 28-03-2018 IPR001107 Band 7 domain AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 9 339 34.198 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 178 4.7E-36 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 Gene3D G3DSA:3.40.50.720 2 197 3.2E-23 T 28-03-2018 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 Gene3D G3DSA:1.10.1040.10 207 350 5.2E-51 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 SUPERFAMILY SSF51735 9 198 1.38E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 SUPERFAMILY SSF48179 197 348 1.28E-51 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PIRSF PIRSF000114 5 349 6.5E-92 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 191 215 3.8E-35 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 13 30 3.8E-35 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 256 273 3.8E-35 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 151 171 3.8E-35 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 216 240 3.8E-35 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 198 337 1.5E-48 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS16445 189fbd0d2b13fef7d87e688f26a1c5ac 350 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 206 227 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 AFA_RS08050 cfb7991aed90ce91c442e8cb5fa2419a 129 SUPERFAMILY SSF55331 2 128 7.16E-40 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily AFA_RS08050 cfb7991aed90ce91c442e8cb5fa2419a 129 Pfam PF14552 Tautomerase enzyme 38 118 5.7E-29 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AFA_RS08050 cfb7991aed90ce91c442e8cb5fa2419a 129 Gene3D G3DSA:3.30.429.10 1 129 1.6E-27 T 28-03-2018 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 39.702 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 9.5E-42 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 SUPERFAMILY SSF51735 123 281 4.48E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 282 2.1E-70 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 Gene3D G3DSA:3.40.50.720 141 264 5.1E-41 T 28-03-2018 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 SUPERFAMILY SSF53223 1 122 6.14E-41 T 28-03-2018 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 Gene3D G3DSA:3.40.50.10860 11 140 2.2E-48 T 28-03-2018 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS10285 745f5398a9a76a1169075e15b882e7af 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 3.2E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AFA_RS02300 4a68c9e030bc1a217925f0c263765840 93 SUPERFAMILY SSF54534 4 92 2.49E-29 T 28-03-2018 AFA_RS02300 4a68c9e030bc1a217925f0c263765840 93 Gene3D G3DSA:3.10.50.40 1 93 5.7E-34 T 28-03-2018 AFA_RS02300 4a68c9e030bc1a217925f0c263765840 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFA_RS02300 4a68c9e030bc1a217925f0c263765840 93 Pfam PF13616 PPIC-type PPIASE domain 4 91 2.3E-24 T 28-03-2018 AFA_RS01815 daa12ba9e640690f38cf199e5e50b875 527 Pfam PF04262 Glutamate-cysteine ligase 10 374 9.1E-155 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFA_RS01815 daa12ba9e640690f38cf199e5e50b875 527 SUPERFAMILY SSF55931 7 512 4.58E-181 T 28-03-2018 AFA_RS01815 daa12ba9e640690f38cf199e5e50b875 527 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 527 197.184 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFA_RS01815 daa12ba9e640690f38cf199e5e50b875 527 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 8 514 6.0E-193 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFA_RS04950 b9b0d01c301a02505ca5248088cd5e04 330 Gene3D G3DSA:1.25.40.180 216 303 0.0019 T 28-03-2018 AFA_RS04950 b9b0d01c301a02505ca5248088cd5e04 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 303 5.5E-42 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS15295 289509b0881f8533e88339f5e5c17a9d 250 SUPERFAMILY SSF52096 12 247 5.81E-43 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS15295 289509b0881f8533e88339f5e5c17a9d 250 Gene3D G3DSA:3.90.226.10 5 250 1.3E-43 T 28-03-2018 AFA_RS15295 289509b0881f8533e88339f5e5c17a9d 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 215 9.7E-25 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 Pfam PF00990 Diguanylate cyclase, GGDEF domain 409 516 2.2E-15 T 28-03-2018 IPR000160 GGDEF domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 Gene3D G3DSA:3.10.580.10 248 398 1.5E-6 T 28-03-2018 AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 SUPERFAMILY SSF141868 6 240 6.8E-55 T 28-03-2018 IPR001633 EAL domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 Gene3D G3DSA:3.30.70.270 399 580 1.2E-27 T 28-03-2018 AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 SUPERFAMILY SSF55073 410 578 3.06E-22 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 SMART SM00267 396 580 5.8E-12 T 28-03-2018 IPR000160 GGDEF domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 Pfam PF00563 EAL domain 7 237 1.1E-41 T 28-03-2018 IPR001633 EAL domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 SMART SM00052 4 242 1.0E-26 T 28-03-2018 IPR001633 EAL domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 Gene3D G3DSA:3.20.20.450 2 247 2.7E-54 T 28-03-2018 IPR001633 EAL domain AFA_RS01370 2ab0c8181333860b629088aebdb78bbe 600 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 420 579 5.3E-15 T 28-03-2018 IPR000160 GGDEF domain AFA_RS04400 98262ff807fd842f28824fa608843d36 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 79 731 4.6E-103 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 Pfam PF00593 TonB dependent receptor 299 728 3.7E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 SUPERFAMILY SSF56935 35 731 4.84E-103 T 28-03-2018 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 Gene3D G3DSA:2.40.170.20 193 731 7.4E-68 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 Gene3D G3DSA:2.170.130.10 29 187 3.4E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 175 5.1E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS04400 98262ff807fd842f28824fa608843d36 731 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 714 731 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Gene3D G3DSA:3.20.19.10 643 883 2.3E-79 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 160 168 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 136 149 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 420 431 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 207 222 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 283 296 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 269 282 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 363 377 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 482 495 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 PRINTS PR00415 Aconitase family signature 193 206 1.3E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Gene3D G3DSA:3.30.499.10 362 565 6.0E-55 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Pfam PF00694 Aconitase C-terminal domain 682 809 8.0E-41 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 25 881 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Pfam PF00330 Aconitase family (aconitate hydratase) 64 551 5.4E-154 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 SUPERFAMILY SSF53732 26 614 1.83E-185 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Gene3D G3DSA:3.30.499.10 23 238 3.9E-57 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 Gene3D G3DSA:3.40.1060.10 239 361 6.1E-38 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS06505 29c5cade9247b10e9cf5eb14533ced68 884 SUPERFAMILY SSF52016 621 882 1.02E-78 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS17240 f4bdf269217c80151279e4dbc8c8f5eb 296 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 32 287 2.0E-91 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 AFA_RS17240 f4bdf269217c80151279e4dbc8c8f5eb 296 Gene3D G3DSA:1.10.3720.10 21 294 6.7E-46 T 28-03-2018 AFA_RS17240 f4bdf269217c80151279e4dbc8c8f5eb 296 SUPERFAMILY SSF161098 36 284 7.72E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS17240 f4bdf269217c80151279e4dbc8c8f5eb 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 286 2.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS17240 f4bdf269217c80151279e4dbc8c8f5eb 296 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 28 287 3.6E-103 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 AFA_RS15095 3beb609296ab5135fe80f1b7aa96acc6 365 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 323 8.5E-56 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS15095 3beb609296ab5135fe80f1b7aa96acc6 365 PIRSF PIRSF039026 1 357 2.0E-112 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS04330 a73fbf205727760c880ca8ebd983ae37 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 3.6E-53 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 AFA_RS04330 a73fbf205727760c880ca8ebd983ae37 208 Pfam PF01300 Telomere recombination 22 198 3.1E-41 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 AFA_RS04330 a73fbf205727760c880ca8ebd983ae37 208 SUPERFAMILY SSF55821 1 203 4.88E-58 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS04330 a73fbf205727760c880ca8ebd983ae37 208 Gene3D G3DSA:3.90.870.10 1 206 1.4E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 220 1.7E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 SUPERFAMILY SSF55785 34 123 5.44E-6 T 28-03-2018 IPR000014 PAS domain AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 Gene3D G3DSA:3.30.565.10 221 374 1.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 SUPERFAMILY SSF47384 144 221 2.16E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 Gene3D G3DSA:3.30.450.20 28 151 8.4E-9 T 28-03-2018 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 SMART SM00388 156 222 6.5E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 Gene3D G3DSA:1.10.287.130 152 219 3.9E-8 T 28-03-2018 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 371 4.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 SMART SM00387 265 375 2.7E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 317 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 331 2.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS12455 7cd2e77956a24df60cce444d7bcaf24f 381 SUPERFAMILY SSF55874 229 372 4.45E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Gene3D G3DSA:2.160.20.60 1274 1569 2.5E-108 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Gene3D G3DSA:3.20.20.70 461 804 7.2E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Pfam PF00310 Glutamine amidotransferases class-II 22 445 9.5E-184 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Gene3D G3DSA:3.60.20.10 22 457 9.7E-161 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Pfam PF01493 GXGXG motif 1298 1485 8.0E-80 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 SUPERFAMILY SSF69336 1267 1554 3.92E-91 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Pfam PF04898 Glutamate synthase central domain 474 760 1.3E-110 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Pfam PF01645 Conserved region in glutamate synthase 824 1220 1.6E-155 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 SUPERFAMILY SSF51395 465 930 1.75E-258 T 28-03-2018 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 SUPERFAMILY SSF51395 960 1256 1.75E-258 T 28-03-2018 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 Gene3D G3DSA:3.20.20.70 805 1273 1.6E-165 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01770 8abda1bd9d4637f40f5a078c0ff0b2af 1577 SUPERFAMILY SSF56235 22 448 1.2E-151 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 Pfam PF00005 ABC transporter 21 162 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 Pfam PF08402 TOBE domain 279 346 2.9E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 Gene3D G3DSA:2.40.50.140 291 341 1.2E-9 T 28-03-2018 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 Gene3D G3DSA:2.40.50.100 241 290 3.4E-9 T 28-03-2018 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 SMART SM00382 29 213 3.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 SUPERFAMILY SSF52540 4 245 2.28E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 Gene3D G3DSA:3.40.50.300 1 240 1.2E-70 T 28-03-2018 AFA_RS09370 8a50c5b6a1b2ccd349172165288b51e9 361 SUPERFAMILY SSF50331 237 359 1.68E-23 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS16985 291607d414ceff5ebfd32103020aacf6 276 Gene3D G3DSA:3.20.20.370 1 263 1.9E-11 T 28-03-2018 AFA_RS16985 291607d414ceff5ebfd32103020aacf6 276 SUPERFAMILY SSF88713 4 127 2.67E-5 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS04685 412c215ba3f73c2832e4db7496079bb2 135 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 131 2.1E-17 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFA_RS04685 412c215ba3f73c2832e4db7496079bb2 135 SUPERFAMILY SSF54637 14 134 1.27E-29 T 28-03-2018 IPR029069 HotDog domain AFA_RS04685 412c215ba3f73c2832e4db7496079bb2 135 Gene3D G3DSA:3.10.129.10 1 133 2.1E-32 T 28-03-2018 AFA_RS04685 412c215ba3f73c2832e4db7496079bb2 135 Pfam PF03061 Thioesterase superfamily 48 124 1.7E-13 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 ProSitePatterns PS00534 Ferrochelatase signature. 218 237 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 Gene3D G3DSA:3.40.50.1400 26 201 1.0E-45 T 28-03-2018 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 Gene3D G3DSA:3.40.50.1400 202 329 4.5E-40 T 28-03-2018 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 Pfam PF00762 Ferrochelatase 31 348 3.5E-109 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 Hamap MF_00323 Ferrochelatase [hemH]. 29 349 36.397 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 SUPERFAMILY SSF53800 30 354 5.1E-105 T 28-03-2018 AFA_RS13760 430920655fcf11e69a1fb9e6b6d508f4 361 TIGRFAM TIGR00109 hemH: ferrochelatase 29 349 1.2E-90 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFA_RS13980 684ea7c170e4ec375b67699fecbdbce4 399 SUPERFAMILY SSF103473 20 392 1.31E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS13980 684ea7c170e4ec375b67699fecbdbce4 399 Gene3D G3DSA:1.20.1250.20 202 398 3.3E-18 T 28-03-2018 AFA_RS13980 684ea7c170e4ec375b67699fecbdbce4 399 Gene3D G3DSA:1.20.1250.20 9 201 1.2E-9 T 28-03-2018 AFA_RS13980 684ea7c170e4ec375b67699fecbdbce4 399 Pfam PF07690 Major Facilitator Superfamily 216 392 2.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS07200 fae54cf3528f88d050a6c967eb9b432a 218 SUPERFAMILY SSF53098 4 200 4.43E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS07200 fae54cf3528f88d050a6c967eb9b432a 218 Gene3D G3DSA:3.30.420.10 1 169 7.5E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS07200 fae54cf3528f88d050a6c967eb9b432a 218 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 179 204 1.1E-4 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor AFA_RS07200 fae54cf3528f88d050a6c967eb9b432a 218 SMART SM00479 2 161 7.6E-5 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS12130 2f62cc4c321f00f6ce30a931f7555a00 220 Gene3D G3DSA:1.10.530.10 3 201 3.0E-13 T 28-03-2018 AFA_RS12130 2f62cc4c321f00f6ce30a931f7555a00 220 Pfam PF01464 Transglycosylase SLT domain 8 146 6.5E-15 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS12130 2f62cc4c321f00f6ce30a931f7555a00 220 SUPERFAMILY SSF53955 13 150 1.99E-14 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS12750 6935dc57e72b6d50e9e21966c8f55c71 125 Gene3D G3DSA:3.30.780.10 31 122 2.1E-16 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 AFA_RS12750 6935dc57e72b6d50e9e21966c8f55c71 125 Pfam PF01253 Translation initiation factor SUI1 47 116 5.8E-15 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 AFA_RS12750 6935dc57e72b6d50e9e21966c8f55c71 125 SUPERFAMILY SSF55159 10 121 2.35E-25 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 AFA_RS12750 6935dc57e72b6d50e9e21966c8f55c71 125 PIRSF PIRSF037511 4 124 1.5E-33 T 28-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 Pfam PF00464 Serine hydroxymethyltransferase 20 396 3.2E-144 T 28-03-2018 AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 Gene3D G3DSA:3.40.640.10 49 287 2.3E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 SUPERFAMILY SSF53383 17 430 1.29E-145 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 PIRSF PIRSF000412 6 423 2.3E-144 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 19 431 45.139 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS14075 3525bea568feb55f449d2d187b130f7d 431 Gene3D G3DSA:3.90.1150.10 288 430 1.2E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 PIRSF PIRSF006621 1 331 2.3E-101 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 322 2.2E-117 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 SUPERFAMILY SSF51395 10 323 1.61E-87 T 28-03-2018 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 324 48.251 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 Pfam PF01207 Dihydrouridine synthase (Dus) 14 317 8.8E-98 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 Gene3D G3DSA:1.10.1200.80 255 328 9.7E-20 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 AFA_RS14425 78f74312471c7b2557b65bf2e9dcce2b 331 Gene3D G3DSA:3.20.20.70 6 252 3.0E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 Pfam PF11741 AMIN domain 47 150 2.4E-24 T 28-03-2018 IPR021731 AMIN domain AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 Gene3D G3DSA:3.40.630.40 223 450 4.0E-56 T 28-03-2018 AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 SMART SM00646 288 443 2.1E-60 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 228 443 2.4E-48 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 SUPERFAMILY SSF53187 370 446 5.96E-56 T 28-03-2018 AFA_RS03955 d8ad3e90519eb3ac894cd51a6d3b9be4 456 SUPERFAMILY SSF53187 226 322 5.96E-56 T 28-03-2018 AFA_RS01840 40f2822f14207ccbcf2d4f90f54c6353 409 Gene3D G3DSA:1.20.1250.20 3 205 1.9E-19 T 28-03-2018 AFA_RS01840 40f2822f14207ccbcf2d4f90f54c6353 409 Gene3D G3DSA:1.20.1250.20 206 401 8.8E-13 T 28-03-2018 AFA_RS01840 40f2822f14207ccbcf2d4f90f54c6353 409 Pfam PF07690 Major Facilitator Superfamily 14 362 2.8E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS01840 40f2822f14207ccbcf2d4f90f54c6353 409 SUPERFAMILY SSF103473 9 401 2.35E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Gene3D G3DSA:3.40.50.300 315 492 2.8E-29 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 SMART SM00382 350 494 2.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Hamap MF_01973 Lon protease [lon]. 14 787 69.394 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 SUPERFAMILY SSF52540 316 602 1.35E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 13 203 3.1E-40 T 28-03-2018 IPR003111 Lon, substrate-binding domain AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Gene3D G3DSA:2.30.130.40 2 120 7.7E-32 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 TIGRFAM TIGR00763 lon: endopeptidase La 15 786 2.4E-296 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 SUPERFAMILY SSF54211 610 785 1.56E-57 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PIRSF PIRSF001174 2 790 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 6.4E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 SMART SM00464 13 205 1.2E-73 T 28-03-2018 IPR003111 Lon, substrate-binding domain AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 691 699 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 688 707 3.0E-55 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 741 759 3.0E-55 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 3.0E-55 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 610 626 3.0E-55 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 718 737 3.0E-55 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Gene3D G3DSA:1.10.8.60 493 591 4.7E-30 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Gene3D G3DSA:3.30.230.10 592 809 2.9E-69 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Gene3D G3DSA:1.10.4060.10 125 214 1.2E-29 T 28-03-2018 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 585 787 5.4E-95 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFA_RS07680 0928eee5ab8a2064533ec00d527c1196 821 SUPERFAMILY SSF88697 13 204 9.94E-52 T 28-03-2018 IPR015947 PUA-like domain AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 SUPERFAMILY SSF55979 250 371 2.62E-33 T 28-03-2018 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 SUPERFAMILY SSF55979 130 248 8.37E-27 T 28-03-2018 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 PIRSF PIRSF000804 3 371 7.6E-107 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 370 7.1E-31 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Gene3D G3DSA:3.10.150.10 252 371 3.5E-27 T 28-03-2018 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 9 370 1.2E-89 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 SUPERFAMILY SSF55979 8 120 1.21E-20 T 28-03-2018 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Gene3D G3DSA:3.10.150.10 128 251 2.0E-28 T 28-03-2018 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 9 122 6.1E-28 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 SMART SM00480 20 367 6.3E-106 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 247 7.1E-31 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS00010 c5f9288046c70d71c6465f62c0cf4a19 371 Gene3D G3DSA:3.10.150.10 2 123 2.3E-24 T 28-03-2018 AFA_RS01465 a1569b41ff7a963b5c810228b435b48e 252 SUPERFAMILY SSF52540 4 244 1.96E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01465 a1569b41ff7a963b5c810228b435b48e 252 SMART SM00382 29 222 3.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01465 a1569b41ff7a963b5c810228b435b48e 252 Gene3D G3DSA:3.40.50.300 1 250 3.3E-52 T 28-03-2018 AFA_RS01465 a1569b41ff7a963b5c810228b435b48e 252 Pfam PF00005 ABC transporter 20 176 1.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 Pfam PF00266 Aminotransferase class-V 155 352 3.6E-13 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 Hamap MF_01970 Kynureninase [kynU]. 3 399 31.922 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 TIGRFAM TIGR01814 kynureninase: kynureninase 8 398 2.0E-95 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 PIRSF PIRSF038800 1 407 3.9E-137 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 Gene3D G3DSA:3.40.640.10 41 291 6.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 Gene3D G3DSA:3.90.1150.10 292 416 2.4E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS02245 09a865d0d5d90c3b7410061e6c82b044 416 SUPERFAMILY SSF53383 4 400 1.19E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS16565 b56f14a26b3f38db52ab9f98253af1b0 421 Pfam PF04932 O-Antigen ligase 187 342 5.3E-9 T 28-03-2018 IPR007016 O-antigen ligase-related AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 Pfam PF12848 ABC transporter 224 310 1.3E-17 T 28-03-2018 IPR032781 ABC-transporter extension domain AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 Gene3D G3DSA:3.40.50.300 2 283 4.8E-48 T 28-03-2018 AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 Gene3D G3DSA:3.40.50.300 284 532 2.4E-50 T 28-03-2018 AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 SUPERFAMILY SSF52540 6 237 2.51E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 SUPERFAMILY SSF52540 297 523 3.76E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 Pfam PF00005 ABC transporter 337 468 1.3E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 Pfam PF00005 ABC transporter 18 184 2.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 SMART SM00382 26 238 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS10630 e0a3322ac6fc767f0f2e9f3606ab9642 532 SMART SM00382 345 514 6.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS06320 8d1e98c0d16f8f81f48f8a25bb6a469f 258 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 154 252 1.3E-31 T 28-03-2018 IPR018754 Protein of unknown function DUF2285 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 155 173 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 28 50 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 76 97 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 111 128 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 174 195 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 PRINTS PR00721 Stomatin signature 131 154 3.3E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 SUPERFAMILY SSF117892 52 186 2.75E-37 T 28-03-2018 IPR001107 Band 7 domain AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 Pfam PF01145 SPFH domain / Band 7 family 25 195 4.9E-32 T 28-03-2018 IPR001107 Band 7 domain AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site AFA_RS08625 d59c2df9cf710e608094ae2e7fac48e7 308 SMART SM00244 21 179 8.3E-54 T 28-03-2018 IPR001107 Band 7 domain AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 128 145 2.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 2.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 2.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 SMART SM00936 288 378 4.1E-28 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 SUPERFAMILY SSF69189 288 380 3.73E-23 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 Gene3D G3DSA:2.60.410.10 305 377 6.7E-18 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 44 267 4.7E-77 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 288 378 1.7E-21 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 SUPERFAMILY SSF56601 4 288 1.93E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS01225 35bfbc95c508ae57c22df4e69c56e455 394 Gene3D G3DSA:3.40.710.10 7 304 2.6E-58 T 28-03-2018 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 SUPERFAMILY SSF64397 3 240 5.1E-58 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 Gene3D G3DSA:3.90.1280.10 234 289 6.0E-21 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 Gene3D G3DSA:3.55.30.10 1 179 3.5E-50 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 SUPERFAMILY SSF118352 233 289 3.79E-18 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 Gene3D G3DSA:1.10.287.480 189 233 3.9E-18 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain AFA_RS12870 5060d30f91868098657394d2eee435eb 303 PIRSF PIRSF005261 2 292 4.5E-68 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFA_RS12870 5060d30f91868098657394d2eee435eb 303 Pfam PF01430 Hsp33 protein 3 281 7.8E-79 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFA_RS13275 e1ba68633b79907a3acaa3a545b71574 258 SUPERFAMILY SSF109998 20 156 3.37E-19 T 28-03-2018 IPR027304 Trigger factor/SurA domain AFA_RS13275 e1ba68633b79907a3acaa3a545b71574 258 SUPERFAMILY SSF54534 119 219 1.11E-29 T 28-03-2018 AFA_RS13275 e1ba68633b79907a3acaa3a545b71574 258 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 157 178 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFA_RS13275 e1ba68633b79907a3acaa3a545b71574 258 Gene3D G3DSA:3.10.50.40 119 245 1.1E-35 T 28-03-2018 AFA_RS13275 e1ba68633b79907a3acaa3a545b71574 258 Pfam PF00639 PPIC-type PPIASE domain 140 219 1.5E-22 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 SMART SM00382 32 224 8.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 SUPERFAMILY SSF52540 6 239 1.36E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 Pfam PF00005 ABC transporter 25 168 6.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 PIRSF PIRSF039137 3 241 3.0E-109 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 239 8.9E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 Gene3D G3DSA:3.40.50.300 2 241 1.3E-59 T 28-03-2018 AFA_RS07460 2ba028045236016b4a29eee28e9d7a8f 245 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 Pfam PF00083 Sugar (and other) transporter 26 231 5.0E-28 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 SUPERFAMILY SSF103473 460 553 3.75E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 SUPERFAMILY SSF103473 20 345 3.75E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 Gene3D G3DSA:1.20.1250.20 238 555 6.0E-26 T 28-03-2018 AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 Gene3D G3DSA:1.20.1250.20 12 236 2.0E-28 T 28-03-2018 AFA_RS11020 16c014fabcbfd62538dceb97f48647e4 557 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 318 8.1E-90 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 Pfam PF00586 AIR synthase related protein, N-terminal domain 25 136 6.6E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 Gene3D G3DSA:3.30.1330.10 1 142 8.9E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 PIRSF PIRSF005303 2 318 1.0E-72 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 301 8.4E-9 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 314 26.513 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 Gene3D G3DSA:3.90.650.10 143 318 3.0E-39 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 SUPERFAMILY SSF55326 4 136 4.71E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain AFA_RS14860 e012967410ece0a192c0c09a358540c6 320 SUPERFAMILY SSF56042 141 302 4.93E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain AFA_RS05135 89200392ffa0e7a21b309a0174b8b5c6 229 SUPERFAMILY SSF161098 8 206 2.4E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05135 89200392ffa0e7a21b309a0174b8b5c6 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 115 6.1E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS05135 89200392ffa0e7a21b309a0174b8b5c6 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 220 6.5E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05135 89200392ffa0e7a21b309a0174b8b5c6 229 Gene3D G3DSA:1.10.3720.10 3 225 7.3E-39 T 28-03-2018 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 SUPERFAMILY SSF90123 164 476 2.22E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 Gene3D G3DSA:1.20.1560.10 159 481 2.4E-37 T 28-03-2018 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 SUPERFAMILY SSF52540 480 714 1.25E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 Pfam PF00664 ABC transporter transmembrane region 182 437 5.1E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 Gene3D G3DSA:3.90.70.10 27 154 2.1E-14 T 28-03-2018 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 Pfam PF00005 ABC transporter 509 656 4.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 ProSitePatterns PS00211 ABC transporters family signature. 629 643 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 SMART SM00382 517 705 2.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 27 720 2.5E-287 T 28-03-2018 IPR017750 ATPase, type I secretion system AFA_RS18080 82a32f93574fc497f6ee869fb659a2a9 729 Gene3D G3DSA:3.40.50.300 487 728 2.5E-68 T 28-03-2018 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 51 495 3.6E-144 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Gene3D G3DSA:2.30.42.10 414 501 6.8E-14 T 28-03-2018 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 SMART SM00228 296 378 3.1E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 SMART SM00228 412 490 1.2E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 SUPERFAMILY SSF50156 434 499 1.24E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 156 176 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 250 267 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 135 147 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 336 348 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 196 220 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 PRINTS PR00834 HtrA/DegQ protease family signature 228 245 4.2E-53 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Pfam PF13365 Trypsin-like peptidase domain 126 257 1.4E-35 T 28-03-2018 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 SUPERFAMILY SSF50494 48 288 3.22E-64 T 28-03-2018 IPR009003 Peptidase S1, PA clan AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Gene3D G3DSA:2.30.42.10 297 400 7.1E-28 T 28-03-2018 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 SUPERFAMILY SSF50156 254 379 1.31E-24 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Pfam PF13180 PDZ domain 434 493 1.2E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Pfam PF13180 PDZ domain 296 387 1.8E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Gene3D G3DSA:2.40.10.10 48 196 1.7E-36 T 28-03-2018 AFA_RS13075 c31710c20d04003b8d0a7e1259c63785 501 Gene3D G3DSA:2.40.10.10 197 296 1.4E-37 T 28-03-2018 AFA_RS02960 dd743825bf51760722e8fe96dbc3e083 306 Gene3D G3DSA:1.10.3470.10 2 299 2.9E-41 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS02960 dd743825bf51760722e8fe96dbc3e083 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 293 6.5E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 157 178 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 SUPERFAMILY SSF53850 9 218 1.15E-64 T 28-03-2018 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 Pfam PF01634 ATP phosphoribosyltransferase 59 215 8.1E-48 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 Gene3D G3DSA:3.40.190.10 131 222 4.3E-20 T 28-03-2018 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 9 222 52.934 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 10 198 7.8E-59 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFA_RS17135 07f67b9a66dc4ea75f621666dd34b156 224 Gene3D G3DSA:3.40.190.10 5 130 7.7E-40 T 28-03-2018 AFA_RS02205 546699cacd994e29766a579fee2b470b 220 SUPERFAMILY SSF55729 46 214 2.23E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS02205 546699cacd994e29766a579fee2b470b 220 Pfam PF00583 Acetyltransferase (GNAT) family 90 195 1.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS02205 546699cacd994e29766a579fee2b470b 220 Gene3D G3DSA:3.40.630.30 37 214 2.3E-16 T 28-03-2018 AFA_RS13255 4cc300fea06f90fab873c2284443b410 389 Gene3D G3DSA:3.40.50.2300 193 371 3.1E-16 T 28-03-2018 AFA_RS13255 4cc300fea06f90fab873c2284443b410 389 Pfam PF13458 Periplasmic binding protein 27 381 1.0E-48 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS13255 4cc300fea06f90fab873c2284443b410 389 SUPERFAMILY SSF53822 28 385 4.24E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS13255 4cc300fea06f90fab873c2284443b410 389 Gene3D G3DSA:3.40.50.2300 24 192 1.1E-28 T 28-03-2018 AFA_RS10715 f27c1f8e738b0a294388689fcb5834fc 252 Pfam PF01925 Sulfite exporter TauE/SafE 9 243 5.5E-20 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS06100 d897e4ed1d7ca72b34556d9ff8b2beeb 339 Gene3D G3DSA:3.40.190.10 136 243 2.0E-6 T 28-03-2018 AFA_RS06100 d897e4ed1d7ca72b34556d9ff8b2beeb 339 PIRSF PIRSF017082 3 337 1.3E-67 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS06100 d897e4ed1d7ca72b34556d9ff8b2beeb 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 330 5.3E-68 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS06100 d897e4ed1d7ca72b34556d9ff8b2beeb 339 SUPERFAMILY SSF53850 113 294 1.49E-8 T 28-03-2018 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 63 84 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 126 146 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 4 26 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 27 43 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 44 61 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PRINTS PR01004 Flagellar FliJ protein signature 108 126 4.1E-15 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 2.4E-29 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 PIRSF PIRSF019404 1 148 2.4E-41 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFA_RS05940 5646f8914f53ab7097c68c6c00aa3431 149 Pfam PF02050 Flagellar FliJ protein 19 142 9.9E-32 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 AFA_RS06140 cd98cd89a7d2245e76e703eb5babc515 314 Pfam PF16220 Domain of unknown function (DUF4880) 14 54 1.9E-8 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS06140 cd98cd89a7d2245e76e703eb5babc515 314 PIRSF PIRSF018266 4 314 1.6E-53 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS06140 cd98cd89a7d2245e76e703eb5babc515 314 Pfam PF04773 FecR protein 108 194 6.7E-15 T 28-03-2018 IPR006860 FecR protein AFA_RS15825 0c199c9528437cb7c2f3fcabd532234f 364 SUPERFAMILY SSF161098 151 344 1.11E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15825 0c199c9528437cb7c2f3fcabd532234f 364 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 152 250 1.3E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS15825 0c199c9528437cb7c2f3fcabd532234f 364 Gene3D G3DSA:1.10.3720.10 26 363 2.1E-40 T 28-03-2018 AFA_RS15825 0c199c9528437cb7c2f3fcabd532234f 364 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 172 358 1.8E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 PIRSF PIRSF004640 16 425 1.4E-125 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 Pfam PF04551 GcpE protein 35 415 2.5E-111 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 23 415 3.1E-115 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 Gene3D G3DSA:3.20.20.70 42 310 1.1E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 23 417 27.499 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFA_RS11570 cddee3a8e2a014b73e0fe278c3d45eed 428 SUPERFAMILY SSF56014 314 425 4.77E-9 T 28-03-2018 AFA_RS16140 26b38488083925e922a42e07adee074a 621 Gene3D G3DSA:2.170.130.10 22 158 3.8E-38 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16140 26b38488083925e922a42e07adee074a 621 SUPERFAMILY SSF56935 32 619 1.18E-110 T 28-03-2018 AFA_RS16140 26b38488083925e922a42e07adee074a 621 Pfam PF00593 TonB dependent receptor 181 619 1.2E-34 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16140 26b38488083925e922a42e07adee074a 621 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 151 2.7E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16140 26b38488083925e922a42e07adee074a 621 Gene3D G3DSA:2.40.170.20 163 620 2.3E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 104 126 2.9E-27 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 80 100 2.9E-27 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 130 148 2.9E-27 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 20 37 2.9E-27 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 13 147 6.2E-44 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 SUPERFAMILY SSF54611 7 148 8.94E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 Gene3D G3DSA:3.10.420.10 8 160 1.1E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 Hamap MF_00821 Protein-export protein SecB [secB]. 1 152 31.215 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS16440 df820d2f48afef0c1ac9e6d235ee8c3c 164 Pfam PF02556 Preprotein translocase subunit SecB 12 151 1.5E-51 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFA_RS07360 4f760dd3b5586a1423caf134213884b9 61 SUPERFAMILY SSF158997 1 55 1.83E-20 T 28-03-2018 AFA_RS07360 4f760dd3b5586a1423caf134213884b9 61 Pfam PF03966 Trm112p-like protein 4 41 2.5E-11 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 AFA_RS07360 4f760dd3b5586a1423caf134213884b9 61 Gene3D G3DSA:2.20.25.10 8 61 8.6E-21 T 28-03-2018 AFA_RS07360 4f760dd3b5586a1423caf134213884b9 61 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 26.246 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 SUPERFAMILY SSF46785 8 86 1.24E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 69 1.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 Gene3D G3DSA:1.10.10.10 10 88 7.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 Gene3D G3DSA:3.40.190.10 180 264 8.1E-20 T 28-03-2018 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 Pfam PF03466 LysR substrate binding domain 94 293 3.2E-34 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 5.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 5.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 5.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 SUPERFAMILY SSF53850 96 297 6.7E-37 T 28-03-2018 AFA_RS14770 d8e19d35832260b3f6d63f559277286a 301 Gene3D G3DSA:3.40.190.10 94 179 1.4E-12 T 28-03-2018 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Gene3D G3DSA:1.10.1040.10 361 449 5.0E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 SUPERFAMILY SSF51735 16 202 5.23E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 SUPERFAMILY SSF52096 503 806 1.34E-40 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Gene3D G3DSA:3.90.226.10 477 807 1.6E-40 T 28-03-2018 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Pfam PF00378 Enoyl-CoA hydratase/isomerase 511 649 3.3E-18 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 204 303 8.2E-10 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 19 201 1.1E-45 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Gene3D G3DSA:1.10.1040.10 202 309 1.0E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 SUPERFAMILY SSF48179 202 320 1.28E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 Gene3D G3DSA:3.40.50.720 1 201 2.2E-42 T 28-03-2018 AFA_RS17075 d99ff8977751cecace33da8b14cd9d9e 810 SUPERFAMILY SSF48179 354 467 6.12E-14 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS11185 8b97cace638df716f7610dd59aa49e72 159 SUPERFAMILY SSF53335 6 124 3.41E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS11185 8b97cace638df716f7610dd59aa49e72 159 Pfam PF13649 Methyltransferase domain 23 113 5.1E-15 T 28-03-2018 AFA_RS11185 8b97cace638df716f7610dd59aa49e72 159 Gene3D G3DSA:3.40.50.150 3 156 3.4E-21 T 28-03-2018 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 6.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 SUPERFAMILY SSF48498 83 214 1.33E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 Gene3D G3DSA:1.10.10.60 2 50 2.8E-16 T 28-03-2018 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 SUPERFAMILY SSF46689 3 70 1.74E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18140 3102fdd0a69dac5268397d86d5f2c458 217 Gene3D G3DSA:1.10.357.10 51 213 6.9E-28 T 28-03-2018 AFA_RS11640 8e569edb28459d112e939572569d2db6 410 SUPERFAMILY SSF46626 331 405 1.92E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11640 8e569edb28459d112e939572569d2db6 410 Gene3D G3DSA:1.20.1510.10 112 308 0.0013 T 28-03-2018 AFA_RS11640 8e569edb28459d112e939572569d2db6 410 Pfam PF06181 Urate oxidase N-terminal 3 304 6.6E-126 T 28-03-2018 IPR010389 Urate oxidase N-terminal AFA_RS11640 8e569edb28459d112e939572569d2db6 410 Gene3D G3DSA:1.10.760.10 309 409 1.0E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 Gene3D G3DSA:3.40.50.620 1 153 1.5E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 PRINTS PR01438 Universal stress protein signature 2 20 1.5E-18 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 PRINTS PR01438 Universal stress protein signature 125 147 1.5E-18 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 PRINTS PR01438 Universal stress protein signature 107 119 1.5E-18 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 SUPERFAMILY SSF52402 1 148 4.02E-36 T 28-03-2018 AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 PIRSF PIRSF006276 1 150 1.5E-18 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS10440 383697451433b3a5b24c24849ca806ef 153 Pfam PF00582 Universal stress protein family 1 147 5.8E-32 T 28-03-2018 IPR006016 UspA GO:0006950 AFA_RS01975 48b6bf7107c48b3893bf1cabfe00e2e3 163 SUPERFAMILY SSF46785 18 148 5.66E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01975 48b6bf7107c48b3893bf1cabfe00e2e3 163 Pfam PF01475 Ferric uptake regulator family 25 143 9.7E-15 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFA_RS01975 48b6bf7107c48b3893bf1cabfe00e2e3 163 Gene3D G3DSA:1.10.10.10 3 96 8.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14095 c2cb068dd19e3a55bf8fde708ccb2360 288 SUPERFAMILY SSF53613 19 276 2.65E-54 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS14095 c2cb068dd19e3a55bf8fde708ccb2360 288 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 18 279 9.2E-45 T 28-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFA_RS14095 c2cb068dd19e3a55bf8fde708ccb2360 288 Pfam PF08543 Phosphomethylpyrimidine kinase 89 277 1.3E-19 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFA_RS14095 c2cb068dd19e3a55bf8fde708ccb2360 288 Gene3D G3DSA:3.40.1190.20 15 278 4.0E-45 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS04110 65bf82044308266eb9c83f2ee7314d19 268 SMART SM00382 36 216 5.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04110 65bf82044308266eb9c83f2ee7314d19 268 Pfam PF00005 ABC transporter 28 166 5.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04110 65bf82044308266eb9c83f2ee7314d19 268 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS04110 65bf82044308266eb9c83f2ee7314d19 268 SUPERFAMILY SSF52540 6 232 1.49E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04110 65bf82044308266eb9c83f2ee7314d19 268 Gene3D G3DSA:3.40.50.300 1 221 1.4E-60 T 28-03-2018 AFA_RS09135 a56cf3aa32cf906c06ea1b6892e17282 192 SUPERFAMILY SSF52540 4 170 8.22E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09135 a56cf3aa32cf906c06ea1b6892e17282 192 Pfam PF13521 AAA domain 5 166 5.8E-38 T 28-03-2018 AFA_RS09135 a56cf3aa32cf906c06ea1b6892e17282 192 Gene3D G3DSA:3.40.50.300 3 171 6.1E-14 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Hamap MF_00671 Protein TolB [tolB]. 23 431 33.531 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:2.60.120.20 331 367 5.5E-6 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:2.60.120.20 287 330 2.6E-11 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:2.60.120.20 241 286 5.1E-8 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:2.60.120.20 173 240 1.2E-9 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:3.40.50.10070 38 172 7.8E-33 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF07676 WD40-like Beta Propeller Repeat 242 277 9.1E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF07676 WD40-like Beta Propeller Repeat 207 232 1.7E-6 T 28-03-2018 IPR011659 WD40-like Beta Propeller AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF07676 WD40-like Beta Propeller Repeat 330 363 5.6E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF07676 WD40-like Beta Propeller Repeat 285 320 1.5E-10 T 28-03-2018 IPR011659 WD40-like Beta Propeller AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF07676 WD40-like Beta Propeller Repeat 374 403 0.092 T 28-03-2018 IPR011659 WD40-like Beta Propeller AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 SUPERFAMILY SSF52964 47 169 1.83E-30 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Pfam PF04052 TolB amino-terminal domain 39 137 5.0E-23 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 29 432 2.2E-151 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 Gene3D G3DSA:2.140.10.30 368 435 7.8E-7 T 28-03-2018 AFA_RS14630 2ac72fdca71378bc9384472d4c56e0c4 436 SUPERFAMILY SSF69304 162 433 1.28E-55 T 28-03-2018 AFA_RS08575 7f875bcee1f661106aa5017113a6c569 443 SUPERFAMILY SSF103473 8 429 5.36E-85 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS08575 7f875bcee1f661106aa5017113a6c569 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS08575 7f875bcee1f661106aa5017113a6c569 443 Gene3D G3DSA:1.20.1250.20 10 213 1.2E-41 T 28-03-2018 AFA_RS08575 7f875bcee1f661106aa5017113a6c569 443 Pfam PF07690 Major Facilitator Superfamily 27 314 1.4E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS08575 7f875bcee1f661106aa5017113a6c569 443 Gene3D G3DSA:1.20.1250.20 231 433 4.4E-24 T 28-03-2018 AFA_RS10665 afde9480aa92fa22787dc78722172542 188 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 153 2.4E-26 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 12 75 1.6E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 SUPERFAMILY SSF52833 3 85 1.47E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 SUPERFAMILY SSF47616 87 203 8.24E-20 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 Gene3D G3DSA:1.20.1050.10 102 207 6.2E-19 T 28-03-2018 AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 Gene3D G3DSA:3.40.30.10 2 101 2.6E-20 T 28-03-2018 AFA_RS12105 a5b2b1234e98764cf5661b8664870c95 207 Pfam PF14497 Glutathione S-transferase, C-terminal domain 123 201 4.4E-7 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 Pfam PF01327 Polypeptide deformylase 5 152 7.2E-50 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 Gene3D G3DSA:3.90.45.10 1 169 5.2E-62 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 SUPERFAMILY SSF56420 2 165 5.76E-61 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 PIRSF PIRSF004749 1 172 1.6E-55 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 Hamap MF_00163 Peptide deformylase [def]. 2 163 30.122 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 159 3.5E-53 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 PRINTS PR01576 Peptide deformylase signature 102 120 2.4E-33 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 PRINTS PR01576 Peptide deformylase signature 90 101 2.4E-33 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 PRINTS PR01576 Peptide deformylase signature 33 62 2.4E-33 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS01140 f54ec3aaaeb78520f93a8d0582df26c2 172 PRINTS PR01576 Peptide deformylase signature 121 150 2.4E-33 T 28-03-2018 IPR023635 Peptide deformylase AFA_RS17185 9e443d991e69345de352705d5a388a36 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 5.2E-17 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 5.2E-17 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 5.2E-17 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 Gene3D G3DSA:1.20.120.20 22 123 9.8E-7 T 28-03-2018 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 148 17.392 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 69 1.6E-20 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AFA_RS17185 9e443d991e69345de352705d5a388a36 163 Pfam PF02416 mttA/Hcf106 family 4 51 6.2E-10 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFA_RS07530 fd321c1722c6f4d94a8a27ef8a2d1c5c 408 Pfam PF00487 Fatty acid desaturase 16 219 1.4E-12 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFA_RS14195 6f16563be086ace1f489da988d98d7ad 692 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 516 676 5.6E-7 T 28-03-2018 AFA_RS14195 6f16563be086ace1f489da988d98d7ad 692 SUPERFAMILY SSF53649 61 330 4.09E-15 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS14195 6f16563be086ace1f489da988d98d7ad 692 SUPERFAMILY SSF49899 515 686 2.22E-12 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain AFA_RS14195 6f16563be086ace1f489da988d98d7ad 692 Gene3D G3DSA:3.40.720.10 47 335 6.1E-17 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS14195 6f16563be086ace1f489da988d98d7ad 692 Gene3D G3DSA:2.60.120.200 431 691 6.0E-18 T 28-03-2018 AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 Gene3D G3DSA:3.10.580.10 280 427 2.1E-24 T 28-03-2018 AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 Gene3D G3DSA:3.30.465.10 428 512 1.4E-18 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 Pfam PF03471 Transporter associated domain 432 511 1.5E-14 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 SMART SM01091 431 512 2.2E-15 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 Pfam PF00571 CBS domain 369 418 1.6E-5 T 28-03-2018 IPR000644 CBS domain AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 SUPERFAMILY SSF56176 429 516 1.12E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 SUPERFAMILY SSF54631 286 421 6.6E-24 T 28-03-2018 AFA_RS01570 fe45c182f9a0938db35a6febe8f12c96 519 Pfam PF03741 Integral membrane protein TerC family 14 203 2.5E-49 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 SUPERFAMILY SSF75217 74 240 2.04E-44 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 PIRSF PIRSF015601 2 241 2.0E-49 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 Gene3D G3DSA:3.40.1280.10 1 241 4.5E-68 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 Pfam PF04452 RNA methyltransferase 20 237 1.7E-58 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 SUPERFAMILY SSF88697 4 61 7.46E-11 T 28-03-2018 IPR015947 PUA-like domain AFA_RS03380 9a8843bc3fba3e19919e664d3bcb61bc 242 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 238 2.3E-47 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS08590 956aec015e5879e311b5e036e15d2778 152 Pfam PF08308 PEGA domain 25 50 3.6E-5 T 28-03-2018 IPR013229 PEGA AFA_RS09385 30d80022b849cdce33374bb07963ab45 435 SUPERFAMILY SSF53850 24 423 2.99E-78 T 28-03-2018 AFA_RS09385 30d80022b849cdce33374bb07963ab45 435 Gene3D G3DSA:3.40.190.10 149 435 2.1E-44 T 28-03-2018 AFA_RS09385 30d80022b849cdce33374bb07963ab45 435 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 139 156 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 AFA_RS09385 30d80022b849cdce33374bb07963ab45 435 Gene3D G3DSA:3.40.190.10 17 148 0.0047 T 28-03-2018 AFA_RS09385 30d80022b849cdce33374bb07963ab45 435 Pfam PF13416 Bacterial extracellular solute-binding protein 42 354 4.2E-47 T 28-03-2018 AFA_RS10510 98e3226ccb15bc39b93b41cadaef8c2e 248 Gene3D G3DSA:3.20.20.190 2 245 3.2E-62 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AFA_RS10510 98e3226ccb15bc39b93b41cadaef8c2e 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 241 2.7E-40 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFA_RS10510 98e3226ccb15bc39b93b41cadaef8c2e 248 SUPERFAMILY SSF51695 6 244 2.88E-60 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AFA_RS10225 51d6e462ab14b1003e255470c4db8c27 237 Gene3D G3DSA:1.20.120.550 153 233 7.9E-4 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain AFA_RS10225 51d6e462ab14b1003e255470c4db8c27 237 Pfam PF01914 MarC family integral membrane protein 14 221 1.7E-39 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFA_RS10225 51d6e462ab14b1003e255470c4db8c27 237 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 14 216 1.8E-37 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFA_RS17640 284c7d9210858d82c69be57e6c4ebb3d 398 Gene3D G3DSA:3.40.640.10 49 297 1.1E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS17640 284c7d9210858d82c69be57e6c4ebb3d 398 SUPERFAMILY SSF53383 6 397 1.73E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS17640 284c7d9210858d82c69be57e6c4ebb3d 398 Gene3D G3DSA:3.90.1150.10 298 398 2.2E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS17640 284c7d9210858d82c69be57e6c4ebb3d 398 Pfam PF00155 Aminotransferase class I and II 48 388 1.0E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS11625 d6080c45f247d1f739e0aef08098968d 310 SUPERFAMILY SSF88713 6 307 7.51E-95 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS11625 d6080c45f247d1f739e0aef08098968d 310 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 6 306 1.7E-157 T 28-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 AFA_RS11625 d6080c45f247d1f739e0aef08098968d 310 Gene3D G3DSA:3.20.20.370 2 310 8.3E-64 T 28-03-2018 AFA_RS11625 d6080c45f247d1f739e0aef08098968d 310 Pfam PF01522 Polysaccharide deacetylase 76 164 2.4E-14 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 SUPERFAMILY SSF51905 1 314 6.97E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 Gene3D G3DSA:3.50.50.60 236 312 0.0059 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 1.2E-72 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 1.2E-116 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.4E-39 T 28-03-2018 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.4E-39 T 28-03-2018 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 3.4E-39 T 28-03-2018 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.4E-39 T 28-03-2018 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 3.4E-39 T 28-03-2018 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 Gene3D G3DSA:3.50.50.60 1 131 1.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 Gene3D G3DSA:3.50.50.60 132 235 1.5E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 303 3.1E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13550 5ef5a3b783b4f51b3173182ea61a8204 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 44 52 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 Gene3D G3DSA:1.10.150.120 80 158 5.3E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 SUPERFAMILY SSF54292 8 93 1.31E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 Gene3D G3DSA:3.10.20.30 4 79 3.9E-24 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 Pfam PF01799 [2Fe-2S] binding domain 78 150 3.4E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 58 1.9E-6 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS14970 8f4b75ef48fbafb7de8dabc70fc574ee 158 SUPERFAMILY SSF47741 89 156 6.67E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 390 1.9E-117 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 SMART SM00382 52 240 4.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 Pfam PF00005 ABC transporter 43 191 1.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 Gene3D G3DSA:3.10.580.10 286 394 6.1E-10 T 28-03-2018 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 SUPERFAMILY SSF54631 275 388 9.39E-10 T 28-03-2018 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 Gene3D G3DSA:3.40.50.300 1 285 4.7E-72 T 28-03-2018 AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 SUPERFAMILY SSF52540 39 269 5.99E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12800 146b92541d620155a9e302c9d8d2850b 429 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 1.0E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 SUPERFAMILY SSF55021 327 395 9.16E-13 T 28-03-2018 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 SUPERFAMILY SSF51735 99 286 9.56E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 SUPERFAMILY SSF52283 3 126 3.19E-41 T 28-03-2018 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 1.1E-36 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 Gene3D G3DSA:3.40.50.720 129 286 1.6E-46 T 28-03-2018 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 Gene3D G3DSA:3.40.50.720 1 128 7.2E-40 T 28-03-2018 AFA_RS02985 c349451b10d262c4c263831ef8db1266 402 Gene3D G3DSA:3.30.70.260 319 398 4.7E-9 T 28-03-2018 AFA_RS08545 a5c564c699af1131ffc6a7a30bb6893b 135 Pfam PF03061 Thioesterase superfamily 47 119 2.4E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS08545 a5c564c699af1131ffc6a7a30bb6893b 135 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 132 5.3E-20 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFA_RS08545 a5c564c699af1131ffc6a7a30bb6893b 135 Gene3D G3DSA:3.10.129.10 1 135 2.2E-27 T 28-03-2018 AFA_RS08545 a5c564c699af1131ffc6a7a30bb6893b 135 SUPERFAMILY SSF54637 5 132 9.77E-28 T 28-03-2018 IPR029069 HotDog domain AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 196 4.7E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 SUPERFAMILY SSF47616 90 207 3.06E-34 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 7.3E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 Gene3D G3DSA:1.20.1050.10 119 227 1.8E-22 T 28-03-2018 AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 SUPERFAMILY SSF52833 1 84 4.18E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10035 a8cb051026ff831e87b52fd162c642c0 232 Gene3D G3DSA:3.40.30.10 2 118 2.5E-33 T 28-03-2018 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.114 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 Pfam PF00831 Ribosomal L29 protein 4 59 7.3E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 SUPERFAMILY SSF46561 1 60 3.53E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 Gene3D G3DSA:1.10.287.310 1 63 5.1E-23 T 28-03-2018 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 1.2E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18230 7fbf4a0c690bf388b48293ba2f2ba6cf 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS04230 2d82f12b7362948eb469bff92df0a9b6 182 Gene3D G3DSA:3.10.450.40 98 172 8.7E-6 T 28-03-2018 AFA_RS04230 2d82f12b7362948eb469bff92df0a9b6 182 Pfam PF03413 Peptidase propeptide and YPEB domain 112 171 4.9E-5 T 28-03-2018 IPR025711 PepSY domain AFA_RS01725 3966738eacac121e0fcfd3f14a1cb54c 166 SUPERFAMILY SSF46626 43 127 2.15E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS01725 3966738eacac121e0fcfd3f14a1cb54c 166 Gene3D G3DSA:1.10.760.10 30 140 1.2E-4 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS12065 31641adf8ea29fae156b69d737f5eef8 427 SUPERFAMILY SSF53383 4 402 7.45E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS12065 31641adf8ea29fae156b69d737f5eef8 427 Gene3D G3DSA:3.40.640.10 53 280 3.6E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS12065 31641adf8ea29fae156b69d737f5eef8 427 Gene3D G3DSA:3.90.1150.10 281 404 1.6E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS12065 31641adf8ea29fae156b69d737f5eef8 427 Pfam PF00155 Aminotransferase class I and II 36 392 3.7E-45 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS08000 ed88aaa98c3b4fdb3c5e40171b8a779a 233 Pfam PF08279 HTH domain 6 59 5.2E-19 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 AFA_RS08000 ed88aaa98c3b4fdb3c5e40171b8a779a 233 Gene3D G3DSA:1.10.10.10 1 63 3.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08000 ed88aaa98c3b4fdb3c5e40171b8a779a 233 Pfam PF13280 WYL domain 142 224 5.0E-14 T 28-03-2018 IPR026881 WYL domain AFA_RS08000 ed88aaa98c3b4fdb3c5e40171b8a779a 233 SUPERFAMILY SSF46785 1 62 1.24E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03660 67357193dba34607fcb2f696c3d49716 397 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 26 387 4.8E-124 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 AFA_RS03660 67357193dba34607fcb2f696c3d49716 397 Pfam PF01098 Cell cycle protein 29 389 6.1E-105 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 AFA_RS03660 67357193dba34607fcb2f696c3d49716 397 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 23 396 39.289 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 AFA_RS16745 473720b471cf8c9b01f4af6f3eeab00e 147 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 139 4.1E-20 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 23 264 7.1E-86 T 28-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00412 Epoxide hydrolase signature 51 66 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00412 Epoxide hydrolase signature 209 225 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00412 Epoxide hydrolase signature 241 263 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 Gene3D G3DSA:3.40.50.1820 14 267 1.2E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 4.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 4.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 4.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 4.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 SUPERFAMILY SSF53474 18 265 6.68E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS08260 ae1bf9a55b183f84d1f5b494f29d3ffd 267 Pfam PF00561 alpha/beta hydrolase fold 27 253 1.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS15805 61f90586f3ffec5a88603c0c1ff29c03 638 Pfam PF01964 Radical SAM ThiC family 139 599 1.8E-197 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFA_RS15805 61f90586f3ffec5a88603c0c1ff29c03 638 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 603 7.4E-211 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFA_RS15805 61f90586f3ffec5a88603c0c1ff29c03 638 Pfam PF13667 ThiC-associated domain 22 99 3.3E-33 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFA_RS15805 61f90586f3ffec5a88603c0c1ff29c03 638 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 605 56.254 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 Pfam PF02261 Aspartate decarboxylase 2 114 3.0E-39 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 SUPERFAMILY SSF50692 3 121 1.74E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 51.772 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 Gene3D G3DSA:2.40.40.20 1 117 1.2E-41 T 28-03-2018 AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 3 125 2.7E-34 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFA_RS00405 9c3ba7b9f83f53b1e6608db82e178501 186 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 4 92 4.0E-37 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 Gene3D G3DSA:3.40.190.10 174 250 1.5E-14 T 28-03-2018 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 SUPERFAMILY SSF53850 92 284 9.05E-32 T 28-03-2018 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 Gene3D G3DSA:3.40.190.10 93 173 2.6E-11 T 28-03-2018 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 SUPERFAMILY SSF46785 3 86 7.44E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 Gene3D G3DSA:1.10.10.10 5 92 1.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15395 b0e03a5e7367c0a19fec73eb06eb798a 285 Pfam PF03466 LysR substrate binding domain 89 283 2.1E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 SUPERFAMILY SSF53335 228 322 8.66E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 SUPERFAMILY SSF53335 38 128 8.66E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 323 35.583 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 37 322 7.9E-101 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 Gene3D G3DSA:1.10.150.170 129 230 6.4E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 PIRSF PIRSF004486 1 324 9.0E-95 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 Pfam PF01795 MraW methylase family 4 322 1.1E-100 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 Gene3D G3DSA:3.40.50.150 31 128 5.9E-6 T 28-03-2018 AFA_RS03630 00141e73ac76d16ddeaaef91eef2a795 356 SUPERFAMILY SSF81799 129 228 1.7E-33 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 SUPERFAMILY SSF53335 7 220 1.84E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 29 219 6.5E-44 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 Pfam PF02527 rRNA small subunit methyltransferase G 26 214 5.4E-45 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 PIRSF PIRSF003078 1 222 2.0E-48 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 Gene3D G3DSA:3.40.50.150 2 223 9.0E-29 T 28-03-2018 AFA_RS18415 0c45c62fc3337ad82832c7d4c3e4d451 223 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 17 218 23.946 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFA_RS02130 dc199ac97ebcf97db77e7ced1b31e8cb 409 Pfam PF02515 CoA-transferase family III 12 379 2.0E-109 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS02130 dc199ac97ebcf97db77e7ced1b31e8cb 409 SUPERFAMILY SSF89796 7 398 1.7E-123 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS02130 dc199ac97ebcf97db77e7ced1b31e8cb 409 Gene3D G3DSA:3.40.50.10540 6 400 1.6E-126 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS15895 22dbc14626cbbeadace1a214a9571680 224 Gene3D G3DSA:3.40.50.2020 4 204 5.6E-48 T 28-03-2018 AFA_RS15895 22dbc14626cbbeadace1a214a9571680 224 SUPERFAMILY SSF53271 10 222 6.19E-46 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS15895 22dbc14626cbbeadace1a214a9571680 224 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 198 1.4E-61 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS15895 22dbc14626cbbeadace1a214a9571680 224 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 224 34.036 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS15895 22dbc14626cbbeadace1a214a9571680 224 Pfam PF00156 Phosphoribosyl transferase domain 46 170 9.4E-16 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFA_RS18110 df9eb8b732b14dc0f6d655079af62fcc 334 SUPERFAMILY SSF161098 143 325 5.49E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18110 df9eb8b732b14dc0f6d655079af62fcc 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 322 1.6E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18110 df9eb8b732b14dc0f6d655079af62fcc 334 Gene3D G3DSA:1.10.3720.10 16 334 1.7E-23 T 28-03-2018 AFA_RS18110 df9eb8b732b14dc0f6d655079af62fcc 334 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 127 333 8.6E-77 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 369 450 2.3E-21 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 460 530 1.3E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 287 357 6.7E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 200 270 4.9E-23 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 28 95 6.2E-5 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 113 181 6.2E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Pfam PF00575 S1 RNA binding domain 372 444 8.7E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 14 123 7.24E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 200 286 3.36E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 6 102 1.5E-6 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 113 181 1.9E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 372 444 2.9E-19 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 285 357 1.4E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 29 97 0.083 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 459 530 4.4E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SMART SM00316 200 270 2.5E-29 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PIRSF PIRSF002111 2 395 4.7E-174 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PIRSF PIRSF002111 369 561 6.3E-48 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 113 195 2.43E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 455 536 9.6E-19 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 105 187 1.8E-9 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 192 276 1.2E-26 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 439 539 1.12E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 265 365 2.93E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 13 530 9.8E-205 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 136 153 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 31 49 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 118 134 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 340 358 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 300 319 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 165 185 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 49 63 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 94 113 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 PRINTS PR00681 Ribosomal protein S1 signature 222 243 1.1E-81 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 Gene3D G3DSA:2.40.50.140 285 358 1.4E-24 T 28-03-2018 AFA_RS11960 f7ca004f9a05f7a6f7f841aecf73105c 572 SUPERFAMILY SSF50249 356 447 2.0E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS12175 330c4980b0adcb2ec4452d09ecf86c12 228 SUPERFAMILY SSF54427 89 225 1.71E-36 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS12175 330c4980b0adcb2ec4452d09ecf86c12 228 PIRSF PIRSF003299 2 226 5.4E-47 T 28-03-2018 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 AFA_RS12175 330c4980b0adcb2ec4452d09ecf86c12 228 Pfam PF04335 VirB8 protein 21 222 6.9E-40 T 28-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 SUPERFAMILY SSF51395 405 759 7.33E-115 T 28-03-2018 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 Gene3D G3DSA:3.50.50.60 1 395 8.3E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 408 740 4.7E-68 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 SUPERFAMILY SSF51905 1 152 7.03E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 SUPERFAMILY SSF51905 254 353 7.03E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 Gene3D G3DSA:3.20.20.70 396 768 2.3E-114 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.1E-9 T 28-03-2018 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.1E-9 T 28-03-2018 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.1E-9 T 28-03-2018 AFA_RS00270 287d6c908de540f84baff5f9a6d07817 778 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 1.1E-9 T 28-03-2018 AFA_RS03315 210f2e67822c3dd33d4589a62e1f549b 388 Gene3D G3DSA:1.10.10.660 29 94 2.6E-22 T 28-03-2018 IPR024033 Uncharacterised domain, YlbE AFA_RS03315 210f2e67822c3dd33d4589a62e1f549b 388 Gene3D G3DSA:3.90.1710.10 95 226 1.8E-26 T 28-03-2018 AFA_RS03315 210f2e67822c3dd33d4589a62e1f549b 388 Gene3D G3DSA:3.90.1700.10 231 382 1.2E-24 T 28-03-2018 AFA_RS03315 210f2e67822c3dd33d4589a62e1f549b 388 Pfam PF06545 Protein of unknown function (DUF1116) 77 282 9.5E-42 T 28-03-2018 IPR009499 Protein of unknown function DUF1116 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.1E-17 T 28-03-2018 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 1.1E-17 T 28-03-2018 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 1.1E-17 T 28-03-2018 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.1E-17 T 28-03-2018 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 SUPERFAMILY SSF51905 8 165 2.43E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 SUPERFAMILY SSF51905 258 358 2.43E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 Gene3D G3DSA:3.50.50.60 7 340 2.8E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS09255 a63e52c60da75b791e9ed9ab32a4bf43 385 Pfam PF01494 FAD binding domain 8 332 8.2E-30 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 5.2E-35 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 Pfam PF12327 FtsZ family, C-terminal domain 221 315 1.5E-31 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 SMART SM00864 15 204 4.6E-103 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 Gene3D G3DSA:3.40.50.1440 11 213 4.5E-38 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 SUPERFAMILY SSF55307 206 324 3.89E-41 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 Gene3D G3DSA:3.30.1330.20 214 323 1.0E-43 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 12 326 4.3E-116 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 SUPERFAMILY SSF52490 15 207 2.75E-62 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 PRINTS PR00423 Cell division protein FtsZ signature 125 146 5.6E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 PRINTS PR00423 Cell division protein FtsZ signature 211 232 5.6E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 PRINTS PR00423 Cell division protein FtsZ signature 188 210 5.6E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 PRINTS PR00423 Cell division protein FtsZ signature 97 117 5.6E-46 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 335 34.854 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 SMART SM00865 206 324 4.8E-53 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 AFA_RS03690 2645c29a2d95543d4f1c1cd60043e3ca 388 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 SUPERFAMILY SSF82861 538 619 1.7E-8 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 Gene3D G3DSA:2.30.30.60 637 687 4.0E-12 T 28-03-2018 AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 SUPERFAMILY SSF82689 703 782 1.57E-10 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 SUPERFAMILY SSF50182 621 686 1.67E-15 T 28-03-2018 IPR010920 LSM domain AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 Gene3D G3DSA:3.30.70.100 694 780 4.0E-10 T 28-03-2018 AFA_RS06585 2b737d68d1edab45f13f4e927d1ee569 799 Pfam PF00924 Mechanosensitive ion channel 579 777 7.0E-40 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFA_RS17170 c2b5badf06b12e0128e8f4892dc5e030 117 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 28 100 2.2E-13 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 AFA_RS17170 c2b5badf06b12e0128e8f4892dc5e030 117 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 11 97 1.8E-27 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFA_RS17170 c2b5badf06b12e0128e8f4892dc5e030 117 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 8 97 20.521 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFA_RS17170 c2b5badf06b12e0128e8f4892dc5e030 117 Gene3D G3DSA:1.10.287.1080 7 104 3.5E-21 T 28-03-2018 AFA_RS17170 c2b5badf06b12e0128e8f4892dc5e030 117 SUPERFAMILY SSF101386 11 102 3.18E-22 T 28-03-2018 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 186 210 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 243 260 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 146 166 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 PRINTS PR00834 HtrA/DegQ protease family signature 329 341 1.2E-52 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 SMART SM00228 289 371 2.0E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 Gene3D G3DSA:2.40.10.10 162 278 7.5E-39 T 28-03-2018 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 SUPERFAMILY SSF50494 62 285 1.25E-62 T 28-03-2018 IPR009003 Peptidase S1, PA clan AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 Gene3D G3DSA:2.40.10.10 53 161 3.0E-28 T 28-03-2018 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 SUPERFAMILY SSF50156 247 372 3.15E-24 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 Gene3D G3DSA:2.30.42.10 284 388 3.6E-25 T 28-03-2018 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 Pfam PF13180 PDZ domain 293 380 1.1E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS17195 ad49b169ba8bc63b22e6460323b4cfce 388 Pfam PF13365 Trypsin-like peptidase domain 116 250 3.2E-31 T 28-03-2018 AFA_RS13575 6b51a09d93ae91272a3e92423b3507cd 165 SMART SM00903 17 162 8.9E-37 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS13575 6b51a09d93ae91272a3e92423b3507cd 165 Gene3D G3DSA:2.30.110.10 6 165 1.1E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS13575 6b51a09d93ae91272a3e92423b3507cd 165 Pfam PF01613 Flavin reductase like domain 18 163 4.0E-27 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS13575 6b51a09d93ae91272a3e92423b3507cd 165 SUPERFAMILY SSF50475 10 161 4.91E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 9.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 275 289 9.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 303 9.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 9.5E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 228 343 8.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 Pfam PF00512 His Kinase A (phospho-acceptor) domain 116 184 1.8E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 SMART SM00388 115 185 6.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 SMART SM00387 227 344 1.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 Gene3D G3DSA:3.30.565.10 186 344 3.4E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 SUPERFAMILY SSF47384 112 184 6.28E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 Gene3D G3DSA:1.10.287.130 96 181 2.1E-6 T 28-03-2018 AFA_RS15575 cba984f645e9f548878b5da724bc0087 344 SUPERFAMILY SSF55874 171 342 1.44E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS16455 1840694316b4e0bb7125d1bf562d10a6 156 Gene3D G3DSA:3.40.1280.10 1 154 1.3E-37 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS16455 1840694316b4e0bb7125d1bf562d10a6 156 Pfam PF00588 SpoU rRNA Methylase family 2 143 2.1E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFA_RS16455 1840694316b4e0bb7125d1bf562d10a6 156 SUPERFAMILY SSF75217 1 153 9.16E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS16455 1840694316b4e0bb7125d1bf562d10a6 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 30.254 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AFA_RS16455 1840694316b4e0bb7125d1bf562d10a6 156 PIRSF PIRSF029256 1 156 9.8E-60 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 SMART SM00345 29 88 3.5E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 SUPERFAMILY SSF46785 23 100 5.86E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 SMART SM00866 108 250 3.1E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 Gene3D G3DSA:1.10.10.10 19 96 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 2.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 2.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 SUPERFAMILY SSF64288 77 255 1.32E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 Pfam PF07702 UTRA domain 113 250 7.2E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 Gene3D G3DSA:3.40.1410.10 107 255 1.6E-34 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS04840 f23e59b3fb160cc0575cb75922302f66 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 88 5.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14690 b067736e76fff952ee33655cef001544 328 SUPERFAMILY SSF51735 4 150 3.72E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14690 b067736e76fff952ee33655cef001544 328 Gene3D G3DSA:3.40.50.720 1 136 3.9E-11 T 28-03-2018 AFA_RS14690 b067736e76fff952ee33655cef001544 328 Pfam PF16654 Diaminopimelic acid dehydrogenase C-terminal domain 124 277 9.0E-75 T 28-03-2018 IPR032094 Meso-diaminopimelate D-dehydrogenase, C-terminal KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 AFA_RS14690 b067736e76fff952ee33655cef001544 328 TIGRFAM TIGR01921 DAP-DH: diaminopimelate dehydrogenase 3 328 1.7E-141 T 28-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 AFA_RS14690 b067736e76fff952ee33655cef001544 328 SUPERFAMILY SSF55347 125 275 3.33E-57 T 28-03-2018 AFA_RS14690 b067736e76fff952ee33655cef001544 328 PIRSF PIRSF025648 2 328 1.2E-140 T 28-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 AFA_RS14690 b067736e76fff952ee33655cef001544 328 Gene3D G3DSA:3.30.360.10 137 271 5.2E-65 T 28-03-2018 AFA_RS01380 859ecfcf0be4091bcb8128819566ea60 124 Pfam PF04379 ApaG domain 16 101 5.2E-39 T 28-03-2018 IPR007474 ApaG domain AFA_RS01380 859ecfcf0be4091bcb8128819566ea60 124 SUPERFAMILY SSF110069 4 124 1.96E-50 T 28-03-2018 IPR007474 ApaG domain AFA_RS01380 859ecfcf0be4091bcb8128819566ea60 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.766 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG AFA_RS01380 859ecfcf0be4091bcb8128819566ea60 124 Gene3D G3DSA:2.60.40.1470 2 124 6.7E-48 T 28-03-2018 IPR007474 ApaG domain AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 322 2.5E-143 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 324 1.6E-32 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 155 1.9E-37 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 PIRSF PIRSF000102 2 328 6.6E-66 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 SUPERFAMILY SSF51735 5 158 8.01E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 SUPERFAMILY SSF56327 160 328 2.16E-59 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 Gene3D G3DSA:3.40.50.720 7 158 1.9E-28 T 28-03-2018 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 Gene3D G3DSA:3.90.110.10 159 326 6.3E-49 T 28-03-2018 AFA_RS04835 b20fc4059e1a40818e2872eb5b1c1907 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.297 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 11 109 1.3E-18 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 10 136 24.352 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 SUPERFAMILY SSF56214 9 135 5.1E-27 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 Gene3D G3DSA:3.90.470.20 6 147 2.2E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 9 136 8.4E-21 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 15 119 9.0E-38 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AFA_RS11810 06a7a5cf33771764c51390457311803f 152 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 9 136 8.2E-27 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 50.994 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 Gene3D G3DSA:3.40.50.1100 202 398 1.8E-37 T 28-03-2018 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 Gene3D G3DSA:3.40.50.1100 13 201 2.7E-45 T 28-03-2018 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 382 7.8E-48 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 SUPERFAMILY SSF53686 7 393 7.2E-146 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 394 3.0E-188 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13190 568417c34c7e9fbf5f0786ac506cbc75 399 PIRSF PIRSF001413 2 398 4.8E-160 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 Pfam PF05954 Phage late control gene D protein (GPD) 32 360 2.7E-51 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 26 530 1.2E-72 T 28-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 SUPERFAMILY SSF69279 21 208 9.35E-35 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 Gene3D G3DSA:3.55.50.10 101 214 4.5E-15 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 SUPERFAMILY SSF69255 397 487 2.43E-22 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 SUPERFAMILY SSF69279 224 397 3.74E-25 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 Gene3D G3DSA:1.20.1420.10 636 908 5.8E-5 T 28-03-2018 AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 21 526 4.8E-82 T 28-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset AFA_RS09930 199cd936dfe6260def5fc277c70e552e 961 Gene3D G3DSA:2.40.50.230 403 488 9.7E-22 T 28-03-2018 IPR006531 Gp5 N-terminal AFA_RS16380 9170daebf65824a6db196b0200c61e57 152 Gene3D G3DSA:3.40.1350.10 41 152 1.2E-28 T 28-03-2018 AFA_RS16380 9170daebf65824a6db196b0200c61e57 152 Hamap MF_00048 UPF0102 protein YraN [yraN]. 35 150 19.228 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 AFA_RS16380 9170daebf65824a6db196b0200c61e57 152 Pfam PF02021 Uncharacterised protein family UPF0102 42 137 1.2E-22 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 AFA_RS16380 9170daebf65824a6db196b0200c61e57 152 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 36 150 6.5E-24 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 AFA_RS16380 9170daebf65824a6db196b0200c61e57 152 SUPERFAMILY SSF52980 37 147 4.52E-14 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS16310 afc28de1a84ce60d13d29b626be6b984 383 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 381 5.5E-116 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFA_RS16310 afc28de1a84ce60d13d29b626be6b984 383 PIRSF PIRSF000267 7 383 6.5E-109 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFA_RS16310 afc28de1a84ce60d13d29b626be6b984 383 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 12 367 7.5E-93 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 SUPERFAMILY SSF109604 365 503 3.24E-11 T 28-03-2018 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 6 708 21.927 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 9 573 1.9E-173 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 Gene3D G3DSA:1.10.730.10 596 705 6.6E-13 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 55 67 5.6E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 410 429 5.6E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 10 23 5.6E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 261 276 5.6E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 334 350 5.6E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 Pfam PF05746 DALR anticodon binding domain 603 701 6.6E-9 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 6 708 3.1E-171 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFA_RS03845 c0947cbfbceeae5bab72242a61d1b281 710 SMART SM00836 606 708 0.0062 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Pfam PF01817 Chorismate mutase type II 13 91 2.4E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Gene3D G3DSA:3.40.190.10 185 259 1.8E-25 T 28-03-2018 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 SMART SM00830 13 94 2.3E-23 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 TIGRFAM TIGR01807 CM_P2: chorismate mutase 9 84 1.4E-21 T 28-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 PIRSF PIRSF001500 2 363 3.1E-134 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Gene3D G3DSA:3.40.190.10 103 184 1.1E-30 T 28-03-2018 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 308 315 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Pfam PF00800 Prephenate dehydratase 96 270 4.5E-60 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 SUPERFAMILY SSF55021 265 360 1.72E-26 T 28-03-2018 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Pfam PF01842 ACT domain 282 345 2.0E-6 T 28-03-2018 IPR002912 ACT domain AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 SUPERFAMILY SSF48600 4 91 2.56E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Gene3D G3DSA:3.30.70.260 272 363 1.5E-28 T 28-03-2018 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 Gene3D G3DSA:1.20.59.10 4 102 1.4E-30 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFA_RS11980 c7148e9adcda0d752fd29140fa9c4c4f 363 SUPERFAMILY SSF53850 95 278 4.45E-56 T 28-03-2018 AFA_RS12960 54f96d24a81e1d9415e067c3033e181b 228 Gene3D G3DSA:3.90.1720.10 28 138 5.9E-13 T 28-03-2018 AFA_RS12960 54f96d24a81e1d9415e067c3033e181b 228 Pfam PF00877 NlpC/P60 family 104 211 2.8E-28 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFA_RS12960 54f96d24a81e1d9415e067c3033e181b 228 Gene3D G3DSA:2.30.260.10 139 215 8.7E-24 T 28-03-2018 AFA_RS12960 54f96d24a81e1d9415e067c3033e181b 228 SUPERFAMILY SSF54001 93 212 1.9E-38 T 28-03-2018 AFA_RS12840 d7d497fca34151dffc46610f9d36f3b0 210 Gene3D G3DSA:3.30.160.150 36 183 1.5E-37 T 28-03-2018 AFA_RS12840 d7d497fca34151dffc46610f9d36f3b0 210 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 22 180 21.107 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AFA_RS12840 d7d497fca34151dffc46610f9d36f3b0 210 Pfam PF04390 Lipopolysaccharide-assembly 59 175 9.0E-8 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AFA_RS17295 66059da4ea1f19a2869c98cd03cc1723 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 312 9.1E-36 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS17295 66059da4ea1f19a2869c98cd03cc1723 346 Gene3D G3DSA:3.40.190.10 1 341 1.8E-5 T 28-03-2018 AFA_RS15410 226a315342323c21a16b02ad0cac769e 143 SUPERFAMILY SSF52833 3 138 1.76E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS15410 226a315342323c21a16b02ad0cac769e 143 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 7.3E-42 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 AFA_RS15410 226a315342323c21a16b02ad0cac769e 143 Gene3D G3DSA:3.40.30.10 1 141 6.0E-43 T 28-03-2018 AFA_RS15410 226a315342323c21a16b02ad0cac769e 143 Pfam PF03960 ArsC family 7 115 3.3E-19 T 28-03-2018 IPR006660 Arsenate reductase-like AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 SMART SM01130 2 290 5.3E-97 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 SUPERFAMILY SSF51569 2 288 3.24E-87 T 28-03-2018 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 281 1.1E-62 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 PIRSF PIRSF001365 1 295 5.1E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 Pfam PF00701 Dihydrodipicolinate synthetase family 3 287 1.3E-64 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 Gene3D G3DSA:3.20.20.70 1 295 1.2E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 3.2E-14 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 3.2E-14 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS03990 035d876231803a0f1644cabf4e8abd2e 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 3.2E-14 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 SMART SM00895 77 201 1.2E-12 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 SMART SM00345 9 67 7.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 Gene3D G3DSA:1.20.120.530 64 219 1.3E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 SUPERFAMILY SSF46785 6 75 7.03E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 Gene3D G3DSA:1.10.10.10 2 63 4.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 5.5E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 Pfam PF07729 FCD domain 77 199 8.7E-22 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS00160 67e49279ef825db087fad5fc6236947e 242 SUPERFAMILY SSF48008 73 208 1.91E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 146 6.3E-21 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 1.6E-56 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 PRINTS PR00481 Cytosol aminopeptidase signature 373 388 1.6E-56 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 1.6E-56 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 1.6E-56 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 1.6E-56 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 Gene3D G3DSA:3.40.220.10 1 167 4.7E-24 T 28-03-2018 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 SUPERFAMILY SSF53187 178 494 3.92E-123 T 28-03-2018 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 183 489 5.8E-125 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 497 36.67 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 SUPERFAMILY SSF52949 1 182 2.0E-30 T 28-03-2018 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFA_RS13020 f12a5bf6cf67ab576169e4e80f8898ef 497 Gene3D G3DSA:3.40.630.10 168 497 6.5E-137 T 28-03-2018 AFA_RS02055 347dc9477958a76189ca759440c1f02d 404 SUPERFAMILY SSF53335 30 394 8.01E-84 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02055 347dc9477958a76189ca759440c1f02d 404 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 91 328 2.7E-45 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 AFA_RS02055 347dc9477958a76189ca759440c1f02d 404 Gene3D G3DSA:3.40.50.150 17 338 4.8E-7 T 28-03-2018 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 Pfam PF00312 Ribosomal protein S15 8 88 6.6E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-28 T 28-03-2018 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 SMART SM01387 8 88 3.8E-53 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 SUPERFAMILY SSF47060 5 89 2.38E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 Gene3D G3DSA:1.10.287.10 2 89 2.6E-35 T 28-03-2018 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 2.2E-39 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS13470 a4cbe7de021609facc26dc923fde4d25 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.028 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15700 1eec15fad100d04a4ad2d35621a893d7 278 Pfam PF00149 Calcineurin-like phosphoesterase 9 155 2.3E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS15700 1eec15fad100d04a4ad2d35621a893d7 278 SUPERFAMILY SSF56300 6 260 1.57E-52 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS15700 1eec15fad100d04a4ad2d35621a893d7 278 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 8 266 8.6E-75 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 AFA_RS15700 1eec15fad100d04a4ad2d35621a893d7 278 Gene3D G3DSA:3.60.21.10 3 277 5.1E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS15700 1eec15fad100d04a4ad2d35621a893d7 278 PIRSF PIRSF000903 7 277 2.9E-98 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 Pfam PF00582 Universal stress protein family 3 141 4.1E-27 T 28-03-2018 IPR006016 UspA GO:0006950 AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 Gene3D G3DSA:3.40.50.620 2 141 2.8E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 SUPERFAMILY SSF52402 3 141 7.67E-28 T 28-03-2018 AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 PRINTS PR01438 Universal stress protein signature 101 113 4.8E-15 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 PRINTS PR01438 Universal stress protein signature 1 19 4.8E-15 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS09465 a7d90f62950316c860d2fd7289b9c846 141 PRINTS PR01438 Universal stress protein signature 119 141 4.8E-15 T 28-03-2018 IPR006015 Universal stress protein A AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 SUPERFAMILY SSF102114 120 367 3.14E-48 T 28-03-2018 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Gene3D G3DSA:2.40.50.140 377 439 9.9E-24 T 28-03-2018 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Pfam PF01938 TRAM domain 375 437 2.9E-7 T 28-03-2018 IPR002792 TRAM domain AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 SMART SM00729 137 362 6.5E-51 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Pfam PF04055 Radical SAM superfamily 143 319 3.6E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 436 1.0E-101 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 438 60.862 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Pfam PF00919 Uncharacterized protein family UPF0004 5 81 6.8E-20 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 436 9.2E-174 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFA_RS16495 d1cc7f7ea0c14bdb71757c2a59459348 439 Gene3D G3DSA:3.80.30.20 134 376 8.0E-42 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 Gene3D G3DSA:1.10.760.10 195 314 2.1E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 Gene3D G3DSA:1.10.760.10 29 194 6.4E-42 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 SUPERFAMILY SSF46626 22 176 7.45E-49 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 Pfam PF03150 Di-haem cytochrome c peroxidase 41 188 3.1E-49 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 SUPERFAMILY SSF46626 175 326 8.34E-43 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 PIRSF PIRSF000294 4 330 4.3E-131 T 28-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 AFA_RS02980 fd90bdcda96e4818176ac8aa0fecdf06 333 Pfam PF00034 Cytochrome c 197 306 3.7E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Pfam PF08264 Anticodon-binding domain of tRNA 677 829 1.5E-38 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 885 949 1.1E-18 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF50677 208 362 1.57E-59 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 950 15.553 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 635 2.2E-201 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Gene3D G3DSA:1.10.287.380 879 948 5.2E-20 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Gene3D G3DSA:1.10.730.10 624 797 1.4E-53 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF46589 885 949 4.97E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 930 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF52374 13 209 3.43E-136 T 28-03-2018 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF52374 361 575 3.43E-136 T 28-03-2018 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF52374 613 645 3.43E-136 T 28-03-2018 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 PRINTS PR00986 Valyl-tRNA synthetase signature 250 267 1.1E-32 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 PRINTS PR00986 Valyl-tRNA synthetase signature 510 528 1.1E-32 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 PRINTS PR00986 Valyl-tRNA synthetase signature 479 500 1.1E-32 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 PRINTS PR00986 Valyl-tRNA synthetase signature 366 379 1.1E-32 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 1.1E-32 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 Gene3D G3DSA:3.40.50.620 14 623 2.0E-135 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS11590 34ddbbef0fecdb29db0c281e653a35f5 950 SUPERFAMILY SSF47323 646 900 2.99E-61 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS01425 4f8f27f2561404a4099f809147b173ee 401 Pfam PF00425 chorismate binding enzyme 126 385 1.0E-69 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFA_RS01425 4f8f27f2561404a4099f809147b173ee 401 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 122 393 4.5E-79 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 AFA_RS01425 4f8f27f2561404a4099f809147b173ee 401 Gene3D G3DSA:3.60.120.10 4 396 3.3E-88 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS01425 4f8f27f2561404a4099f809147b173ee 401 SUPERFAMILY SSF56322 26 397 6.15E-85 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 Gene3D G3DSA:3.40.50.150 1 194 6.7E-31 T 28-03-2018 AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 122 128 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 PIRSF PIRSF004553 5 184 1.7E-36 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 Pfam PF03602 Conserved hypothetical protein 95 6 180 3.6E-44 T 28-03-2018 AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 SUPERFAMILY SSF53335 6 178 1.7E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS14895 c44e2e7e45d4fc22fd364a13dfb60117 209 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 4 180 2.1E-36 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFA_RS02000 99bc46c74de92cde9983efa02e27751e 225 SUPERFAMILY SSF55781 80 212 2.7E-7 T 28-03-2018 IPR029016 GAF domain-like AFA_RS02000 99bc46c74de92cde9983efa02e27751e 225 Pfam PF04340 Protein of unknown function, DUF484 5 212 3.8E-30 T 28-03-2018 IPR007435 Protein of unknown function DUF484 AFA_RS02000 99bc46c74de92cde9983efa02e27751e 225 Gene3D G3DSA:3.30.450.40 42 213 2.7E-12 T 28-03-2018 IPR029016 GAF domain-like AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 SUPERFAMILY SSF50156 85 181 4.73E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 Pfam PF13180 PDZ domain 127 181 8.7E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 439 4.3E-110 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 SMART SM00228 208 275 7.9E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 SMART SM00228 114 184 0.0051 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 Gene3D G3DSA:2.30.42.10 211 305 1.1E-12 T 28-03-2018 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 Pfam PF02163 Peptidase family M50 7 426 9.4E-82 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 Gene3D G3DSA:2.30.42.10 23 190 4.0E-12 T 28-03-2018 AFA_RS10175 dfb2809a561bcc857e3927ee0cc8dc61 440 SUPERFAMILY SSF50156 217 285 2.5E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS04490 4b07259bb3305832b3180b81f9e38eb5 116 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 109 42.73 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit AFA_RS04490 4b07259bb3305832b3180b81f9e38eb5 116 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 8 101 6.0E-32 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit AFA_RS04490 4b07259bb3305832b3180b81f9e38eb5 116 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 9 104 1.5E-36 T 28-03-2018 IPR009662 Malonate decarboxylase delta subunit AFA_RS04490 4b07259bb3305832b3180b81f9e38eb5 116 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 26 105 3.0E-24 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein AFA_RS18120 8d842ddc02b5b77aefdc18281a54cefd 312 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 52 261 9.0E-53 T 28-03-2018 AFA_RS18120 8d842ddc02b5b77aefdc18281a54cefd 312 SUPERFAMILY SSF53850 48 282 1.31E-37 T 28-03-2018 AFA_RS18120 8d842ddc02b5b77aefdc18281a54cefd 312 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 5 255 6.1E-50 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 AFA_RS18120 8d842ddc02b5b77aefdc18281a54cefd 312 Gene3D G3DSA:3.40.190.10 41 132 1.4E-5 T 28-03-2018 AFA_RS18120 8d842ddc02b5b77aefdc18281a54cefd 312 Gene3D G3DSA:3.40.190.10 133 281 8.1E-25 T 28-03-2018 AFA_RS00850 5d573b59e0216ef146fa482ab505bc2d 318 Pfam PF04536 TPM domain 54 175 1.0E-40 T 28-03-2018 IPR007621 TPM domain AFA_RS09475 69407e8b062076853468ccaacf41e65d 405 Gene3D G3DSA:1.20.1250.20 208 404 1.8E-24 T 28-03-2018 AFA_RS09475 69407e8b062076853468ccaacf41e65d 405 SUPERFAMILY SSF103473 21 397 6.28E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS09475 69407e8b062076853468ccaacf41e65d 405 Gene3D G3DSA:1.20.1250.20 6 199 1.4E-17 T 28-03-2018 AFA_RS09475 69407e8b062076853468ccaacf41e65d 405 Pfam PF07690 Major Facilitator Superfamily 45 352 8.4E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 SUPERFAMILY SSF51735 306 485 7.34E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Gene3D G3DSA:3.90.226.10 5 208 6.5E-44 T 28-03-2018 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 SUPERFAMILY SSF48179 588 639 5.78E-5 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Gene3D G3DSA:3.40.50.720 255 484 7.7E-49 T 28-03-2018 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Pfam PF00378 Enoyl-CoA hydratase/isomerase 32 205 1.1E-27 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 SUPERFAMILY SSF52096 11 296 1.62E-50 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 SUPERFAMILY SSF48179 485 584 2.38E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Gene3D G3DSA:1.10.1040.10 485 580 3.2E-24 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 486 575 6.5E-24 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 310 483 2.2E-46 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS18155 73808bc47ece37e0da632f1504ce1f4c 647 Gene3D G3DSA:1.10.1040.10 591 641 0.63 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS03680 3507ad8742621835428c594aa145cdb2 263 Pfam PF08478 POTRA domain, FtsQ-type 53 110 9.9E-13 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type AFA_RS03680 3507ad8742621835428c594aa145cdb2 263 Pfam PF03799 Cell division protein FtsQ 114 245 5.8E-23 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB AFA_RS03680 3507ad8742621835428c594aa145cdb2 263 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 253 22.001 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 AFA_RS08795 9388ce8d911409412b6b096cbf183aad 186 Gene3D G3DSA:3.30.300.130 82 185 2.7E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain AFA_RS08795 9388ce8d911409412b6b096cbf183aad 186 Pfam PF01883 Iron-sulfur cluster assembly protein 89 163 1.5E-14 T 28-03-2018 IPR002744 MIP18 family-like AFA_RS08795 9388ce8d911409412b6b096cbf183aad 186 SUPERFAMILY SSF117916 84 185 1.99E-26 T 28-03-2018 IPR034904 Fe-S cluster assembly domain AFA_RS08795 9388ce8d911409412b6b096cbf183aad 186 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 9 185 2.3E-65 T 28-03-2018 IPR017776 FeS assembly SUF system protein SufT, putative AFA_RS07690 595247c7650686cefd4de0688649628f 186 Pfam PF13302 Acetyltransferase (GNAT) domain 11 152 2.2E-35 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS07690 595247c7650686cefd4de0688649628f 186 Gene3D G3DSA:3.40.630.30 2 186 2.5E-28 T 28-03-2018 AFA_RS07690 595247c7650686cefd4de0688649628f 186 SUPERFAMILY SSF55729 3 154 2.38E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 170 5.0E-64 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 82 6.3E-25 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 SUPERFAMILY SSF54768 15 83 8.27E-21 T 28-03-2018 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 34.282 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 Gene3D G3DSA:3.30.160.20 17 79 3.1E-22 T 28-03-2018 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 3.5E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 SUPERFAMILY SSF54211 86 166 8.09E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS18015 2ec2c991a8be501cd0963a63e530160a 173 Gene3D G3DSA:3.30.230.10 83 173 3.3E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS15940 e29f24e610496708fa637bffc8bbd558 456 Gene3D G3DSA:1.20.1250.20 15 235 3.2E-32 T 28-03-2018 AFA_RS15940 e29f24e610496708fa637bffc8bbd558 456 SUPERFAMILY SSF103473 18 436 2.49E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS15940 e29f24e610496708fa637bffc8bbd558 456 Gene3D G3DSA:1.20.1250.20 236 439 6.2E-16 T 28-03-2018 AFA_RS15940 e29f24e610496708fa637bffc8bbd558 456 Pfam PF07690 Major Facilitator Superfamily 31 397 5.8E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS10830 a24b110d84a77a55c729ea48204ad686 275 Pfam PF01435 Peptidase family M48 76 261 3.0E-38 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFA_RS10830 a24b110d84a77a55c729ea48204ad686 275 Gene3D G3DSA:3.30.2010.10 67 165 4.3E-23 T 28-03-2018 AFA_RS06640 00ae23e1390a7b193308b77b6f7a9da2 114 Pfam PF00893 Small Multidrug Resistance protein 7 98 2.6E-27 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 AFA_RS06640 00ae23e1390a7b193308b77b6f7a9da2 114 SUPERFAMILY SSF103481 10 110 9.02E-22 T 28-03-2018 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 SUPERFAMILY SSF53383 2 423 1.27E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 Gene3D G3DSA:3.40.640.10 183 311 5.0E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 4.9E-186 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 Gene3D G3DSA:3.90.1150.10 312 427 3.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 102.422 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 Pfam PF00202 Aminotransferase class-III 32 415 1.2E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS15735 bb0a4fa9687c29cd2e4bb2dad826f9ed 427 Gene3D G3DSA:3.90.1150.10 1 182 1.1E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS06220 b4540b070fab9f30036d4caf53ec03d4 334 Pfam PF04143 Sulphur transport 24 326 2.4E-57 T 28-03-2018 IPR007272 Sulphur transport domain AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 SUPERFAMILY SSF51556 62 419 1.39E-78 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 Gene3D G3DSA:2.30.40.10 7 72 3.1E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 Gene3D G3DSA:3.20.20.140 73 414 1.4E-70 T 28-03-2018 AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 Pfam PF07969 Amidohydrolase family 52 248 1.5E-13 T 28-03-2018 IPR013108 Amidohydrolase 3 AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 Pfam PF07969 Amidohydrolase family 333 464 1.6E-19 T 28-03-2018 IPR013108 Amidohydrolase 3 AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 SUPERFAMILY SSF51338 9 61 1.87E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17400 0f9874b3f31628765008f2fd7577e2c1 494 SUPERFAMILY SSF51338 419 464 1.87E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS03905 3430107848dfc3f36819833c0bde3c34 232 Gene3D G3DSA:1.10.8.60 159 225 1.4E-12 T 28-03-2018 AFA_RS03905 3430107848dfc3f36819833c0bde3c34 232 Pfam PF00308 Bacterial dnaA protein 89 205 1.1E-9 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA AFA_RS03905 3430107848dfc3f36819833c0bde3c34 232 SUPERFAMILY SSF52540 27 222 2.78E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03905 3430107848dfc3f36819833c0bde3c34 232 Gene3D G3DSA:3.40.50.300 4 156 5.7E-11 T 28-03-2018 AFA_RS03905 3430107848dfc3f36819833c0bde3c34 232 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 4 224 3.4E-68 T 28-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Hamap MF_01183 Chaperone SurA [surA]. 18 475 30.375 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Pfam PF00639 PPIC-type PPIASE domain 213 304 2.3E-17 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 SUPERFAMILY SSF54534 209 307 3.86E-23 T 28-03-2018 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Pfam PF13616 PPIC-type PPIASE domain 332 430 4.8E-27 T 28-03-2018 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 SUPERFAMILY SSF54534 327 429 2.68E-30 T 28-03-2018 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Pfam PF09312 SurA N-terminal domain 49 166 1.6E-29 T 28-03-2018 IPR015391 SurA N-terminal AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Gene3D G3DSA:3.10.50.40 201 316 5.1E-21 T 28-03-2018 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Gene3D G3DSA:3.10.50.40 329 440 2.7E-31 T 28-03-2018 AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 SUPERFAMILY SSF109998 49 236 2.55E-39 T 28-03-2018 IPR027304 Trigger factor/SurA domain AFA_RS03810 5b60a6be93e8cb645827a4453fd156a7 483 Gene3D G3DSA:1.10.4030.10 45 172 8.4E-26 T 28-03-2018 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 Gene3D G3DSA:1.25.40.10 168 270 1.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 Gene3D G3DSA:2.40.160.60 552 827 0.0025 T 28-03-2018 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 SUPERFAMILY SSF48452 315 483 6.53E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 SUPERFAMILY SSF48452 61 256 6.53E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 Gene3D G3DSA:1.25.40.10 286 541 3.2E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 TIGRFAM TIGR03939 PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA 41 835 4.5E-173 T 28-03-2018 IPR023870 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA GO:0022891|GO:0042710 AFA_RS08840 25c2aa450299bd83879498b28e1b08bc 835 Gene3D G3DSA:1.25.40.10 55 167 5.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS01935 9df2442d5769801f835024b30c3bb979 187 SUPERFAMILY SSF89028 8 178 4.32E-55 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 AFA_RS01935 9df2442d5769801f835024b30c3bb979 187 Gene3D G3DSA:1.20.1200.10 17 183 6.2E-57 T 28-03-2018 AFA_RS01935 9df2442d5769801f835024b30c3bb979 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 33 178 8.0E-39 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 AFA_RS01935 9df2442d5769801f835024b30c3bb979 187 Pfam PF01923 Cobalamin adenosyltransferase 8 165 1.6E-54 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 AFA_RS01935 9df2442d5769801f835024b30c3bb979 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 178 9.2E-57 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 82 2.4E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 SUPERFAMILY SSF52833 8 98 2.44E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 Pfam PF13410 Glutathione S-transferase, C-terminal domain 136 196 1.8E-8 T 28-03-2018 AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 Gene3D G3DSA:1.20.1050.10 78 211 1.0E-12 T 28-03-2018 AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 Gene3D G3DSA:3.40.30.10 3 77 1.3E-17 T 28-03-2018 AFA_RS15235 73315f7e57d66f9bcf4de6e6deb67fd2 227 SUPERFAMILY SSF47616 93 215 1.39E-13 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like AFA_RS01470 146a91ee9d1b9579209dcd2fa71560ce 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 296 2.6E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS01470 146a91ee9d1b9579209dcd2fa71560ce 312 Gene3D G3DSA:1.10.3470.10 16 310 2.2E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 Gene3D G3DSA:3.90.380.10 150 445 8.7E-70 T 28-03-2018 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 SUPERFAMILY SSF50022 14 171 8.77E-46 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 Pfam PF00355 Rieske [2Fe-2S] domain 52 137 3.3E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 SUPERFAMILY SSF55961 171 446 1.57E-67 T 28-03-2018 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 Gene3D G3DSA:2.102.10.10 39 149 2.9E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 95 118 - T 28-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 109 129 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 196 218 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 37 62 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 155 181 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 67 82 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 88 108 4.2E-47 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS08555 6cd9c8d5752205c571ed1757ea61cde8 450 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 203 388 2.9E-17 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 Gene3D G3DSA:2.40.50.140 51 116 2.2E-21 T 28-03-2018 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 Gene3D G3DSA:3.40.50.150 117 483 2.6E-50 T 28-03-2018 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 300 479 7.1E-13 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 SUPERFAMILY SSF53335 110 484 1.18E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 52 484 65.435 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 411 445 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 SUPERFAMILY SSF50249 53 107 1.09E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 58 477 1.2E-90 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 AFA_RS10575 bed05762d2cdf42935ad984a8ca245e8 484 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 467 477 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site AFA_RS08710 3a9b82726ad451b8c2e5cc8733e3b45a 225 Gene3D G3DSA:2.160.20.80 131 210 6.6E-18 T 28-03-2018 AFA_RS08710 3a9b82726ad451b8c2e5cc8733e3b45a 225 Gene3D G3DSA:2.160.20.80 3 130 3.2E-19 T 28-03-2018 AFA_RS08710 3a9b82726ad451b8c2e5cc8733e3b45a 225 SUPERFAMILY SSF141571 20 195 4.24E-31 T 28-03-2018 AFA_RS08710 3a9b82726ad451b8c2e5cc8733e3b45a 225 Pfam PF13599 Pentapeptide repeats (9 copies) 126 199 7.6E-10 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS08710 3a9b82726ad451b8c2e5cc8733e3b45a 225 Pfam PF13599 Pentapeptide repeats (9 copies) 25 103 1.5E-12 T 28-03-2018 IPR001646 Pentapeptide repeat AFA_RS08020 effbe815a84a7b80f24f94dd38f52054 155 Pfam PF02657 Fe-S metabolism associated domain 22 139 4.8E-42 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like AFA_RS08020 effbe815a84a7b80f24f94dd38f52054 155 SUPERFAMILY SSF82649 11 144 6.8E-42 T 28-03-2018 AFA_RS08020 effbe815a84a7b80f24f94dd38f52054 155 Gene3D G3DSA:3.90.1010.10 1 145 4.2E-47 T 28-03-2018 AFA_RS15690 ca14f1c8b3a532869c478009f729e7fe 239 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 18 238 2.7E-89 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 AFA_RS15690 ca14f1c8b3a532869c478009f729e7fe 239 Pfam PF00912 Transglycosylase 62 233 3.1E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS15690 ca14f1c8b3a532869c478009f729e7fe 239 SUPERFAMILY SSF53955 43 236 1.04E-58 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS15690 ca14f1c8b3a532869c478009f729e7fe 239 Gene3D G3DSA:1.10.3810.10 46 238 5.4E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS15690 ca14f1c8b3a532869c478009f729e7fe 239 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 11 239 40.861 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 Gene3D G3DSA:3.40.140.10 1 118 9.9E-12 T 28-03-2018 AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 Gene3D G3DSA:3.90.1720.10 119 260 1.5E-11 T 28-03-2018 AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 Pfam PF00877 NlpC/P60 family 129 254 1.5E-12 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 Pfam PF14464 Prokaryotic homologs of the JAB domain 4 103 8.1E-16 T 28-03-2018 IPR028090 JAB domain, prokaryotic AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 SUPERFAMILY SSF102712 135 144 5.89E-16 T 28-03-2018 AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 SUPERFAMILY SSF102712 1 107 5.89E-16 T 28-03-2018 AFA_RS07100 66ebb0abf1f398e1cee1d9f0c5d8ea99 260 SUPERFAMILY SSF54001 125 257 7.16E-11 T 28-03-2018 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 363 9.0E-110 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 545 24.116 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR01900 YidC translocation/secretion protein signature 498 522 4.2E-21 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR01900 YidC translocation/secretion protein signature 350 366 4.2E-21 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR01900 YidC translocation/secretion protein signature 479 494 4.2E-21 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 Pfam PF02096 60Kd inner membrane protein 365 542 7.6E-58 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 364 542 2.2E-67 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 509 532 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 335 355 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 2 23 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 227 245 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 262 277 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 473 495 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 173 193 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 426 449 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 PRINTS PR00701 60kDa inner membrane protein signature 86 107 2.5E-68 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AFA_RS18590 5d40e78408620c92efa611d1595f83d0 555 Pfam PF14849 YidC periplasmic domain 81 354 1.2E-79 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal AFA_RS00445 e41a11c6ecb8dab4e764e6e2098b067c 319 Pfam PF16220 Domain of unknown function (DUF4880) 7 47 2.8E-12 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS00445 e41a11c6ecb8dab4e764e6e2098b067c 319 PIRSF PIRSF018266 2 318 6.9E-89 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS00445 e41a11c6ecb8dab4e764e6e2098b067c 319 Pfam PF04773 FecR protein 108 205 2.2E-19 T 28-03-2018 IPR006860 FecR protein AFA_RS07275 97cdb94ad5e9371251c1c39df0ee0a56 338 Pfam PF13343 Bacterial extracellular solute-binding protein 77 324 2.3E-50 T 28-03-2018 AFA_RS07275 97cdb94ad5e9371251c1c39df0ee0a56 338 Gene3D G3DSA:3.40.190.10 26 141 2.1E-10 T 28-03-2018 AFA_RS07275 97cdb94ad5e9371251c1c39df0ee0a56 338 Gene3D G3DSA:3.40.190.10 142 336 3.5E-31 T 28-03-2018 AFA_RS07275 97cdb94ad5e9371251c1c39df0ee0a56 338 SUPERFAMILY SSF53850 37 329 1.22E-63 T 28-03-2018 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 SUPERFAMILY SSF54862 3 105 2.19E-22 T 28-03-2018 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 Pfam PF00037 4Fe-4S binding domain 34 55 1.7E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 Gene3D G3DSA:3.30.70.20 46 104 5.5E-8 T 28-03-2018 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 Gene3D G3DSA:3.30.70.20 2 45 6.0E-12 T 28-03-2018 AFA_RS13210 c9bb1f818617a741bdb90482bd877a50 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 2.5E-16 T 28-03-2018 IPR022569 Ferredoxin, C-terminal AFA_RS08780 57c9f74ac30b83c80734fc0d95bc709c 435 Pfam PF01458 Uncharacterized protein family (UPF0051) 175 400 2.5E-72 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFA_RS08780 57c9f74ac30b83c80734fc0d95bc709c 435 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 142 416 5.3E-84 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 AFA_RS08780 57c9f74ac30b83c80734fc0d95bc709c 435 SUPERFAMILY SSF101960 23 425 5.75E-102 T 28-03-2018 AFA_RS03085 a7fd1e1cf83a234de044aca13b53960d 85 SUPERFAMILY SSF54285 7 85 4.11E-16 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFA_RS03085 a7fd1e1cf83a234de044aca13b53960d 85 Gene3D G3DSA:3.10.20.30 7 85 3.7E-19 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS03085 a7fd1e1cf83a234de044aca13b53960d 85 Pfam PF02597 ThiS family 9 85 2.0E-16 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 AFA_RS03085 a7fd1e1cf83a234de044aca13b53960d 85 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 8 85 2.3E-20 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 AFA_RS12445 e64904d18e1156011493a23690c84d36 310 SUPERFAMILY SSF53850 90 292 2.79E-46 T 28-03-2018 AFA_RS12445 e64904d18e1156011493a23690c84d36 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12445 e64904d18e1156011493a23690c84d36 310 Gene3D G3DSA:3.40.190.10 174 263 2.0E-24 T 28-03-2018 AFA_RS12445 e64904d18e1156011493a23690c84d36 310 Gene3D G3DSA:1.10.10.10 3 84 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12445 e64904d18e1156011493a23690c84d36 310 Gene3D G3DSA:3.40.190.10 89 173 2.4E-12 T 28-03-2018 AFA_RS12445 e64904d18e1156011493a23690c84d36 310 SUPERFAMILY SSF46785 4 85 7.22E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12445 e64904d18e1156011493a23690c84d36 310 Pfam PF03466 LysR substrate binding domain 90 288 1.5E-46 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 SMART SM00937 63 178 2.7E-63 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 Pfam PF00472 RF-1 domain 214 321 6.5E-43 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 Pfam PF03462 PCRF domain 13 203 9.0E-73 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 357 3.5E-160 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 Gene3D G3DSA:3.30.160.20 210 291 1.1E-33 T 28-03-2018 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.048 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 Gene3D G3DSA:1.20.58.410 3 95 2.0E-15 T 28-03-2018 AFA_RS16675 0e19f42c5bb81a5251d54fd8703fbd85 359 SUPERFAMILY SSF75620 12 352 8.76E-136 T 28-03-2018 AFA_RS16635 d44355da39bcefab7d38d7f21c30ef93 124 Pfam PF03899 ATP synthase I chain 13 108 6.3E-7 T 28-03-2018 IPR005598 ATP synthase protein I AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 SUPERFAMILY SSF51395 5 376 3.17E-96 T 28-03-2018 AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 Pfam PF01070 FMN-dependent dehydrogenase 13 375 4.4E-126 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 Gene3D G3DSA:3.20.20.70 2 379 2.2E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 379 72.44 T 28-03-2018 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 AFA_RS02215 790175d2558afb15fd287aa5fb56f2fe 379 PIRSF PIRSF000138 1 379 4.8E-122 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 SUPERFAMILY SSF52540 19 218 1.27E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 Pfam PF06144 DNA polymerase III, delta subunit 25 198 4.9E-24 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 SUPERFAMILY SSF48019 220 346 1.19E-27 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 Gene3D G3DSA:1.20.272.10 231 352 2.4E-24 T 28-03-2018 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 Gene3D G3DSA:3.40.50.300 3 148 5.2E-15 T 28-03-2018 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 22 345 3.3E-80 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 AFA_RS12845 ccfc15ceecbf9a5e266c8ca5de73f613 353 Gene3D G3DSA:1.10.8.60 151 230 1.0E-23 T 28-03-2018 AFA_RS02995 0f0652f28b11cb8991100f7fc6846d83 134 Pfam PF01152 Bacterial-like globin 6 106 3.0E-5 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 AFA_RS02995 0f0652f28b11cb8991100f7fc6846d83 134 SUPERFAMILY SSF46458 5 115 2.26E-23 T 28-03-2018 IPR009050 Globin-like AFA_RS02995 0f0652f28b11cb8991100f7fc6846d83 134 Gene3D G3DSA:1.10.490.10 2 123 1.4E-20 T 28-03-2018 AFA_RS17330 7f1196d3e0eb476eb443b8bfc331e6eb 290 SUPERFAMILY SSF140959 33 290 2.22E-104 T 28-03-2018 AFA_RS17330 7f1196d3e0eb476eb443b8bfc331e6eb 290 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 27 290 4.9E-133 T 28-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 AFA_RS17330 7f1196d3e0eb476eb443b8bfc331e6eb 290 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 27 290 41.587 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFA_RS17330 7f1196d3e0eb476eb443b8bfc331e6eb 290 Pfam PF03301 Tryptophan 2,3-dioxygenase 21 290 1.9E-71 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AFA_RS17470 23ddb23de5e82e4c28148436f254e616 334 PIRSF PIRSF018266 8 332 2.2E-93 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS17470 23ddb23de5e82e4c28148436f254e616 334 Pfam PF16220 Domain of unknown function (DUF4880) 20 60 6.6E-12 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS17470 23ddb23de5e82e4c28148436f254e616 334 Pfam PF04773 FecR protein 127 220 3.4E-22 T 28-03-2018 IPR006860 FecR protein AFA_RS03725 5f92907d91cc1ee5f7f522804ec41842 133 Pfam PF03061 Thioesterase superfamily 29 103 3.4E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS03725 5f92907d91cc1ee5f7f522804ec41842 133 Gene3D G3DSA:3.10.129.10 1 133 1.6E-33 T 28-03-2018 AFA_RS03725 5f92907d91cc1ee5f7f522804ec41842 133 SUPERFAMILY SSF54637 10 132 9.83E-36 T 28-03-2018 IPR029069 HotDog domain AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 175 1.6E-56 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 PIRSF PIRSF002070 1 118 1.8E-35 T 28-03-2018 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 PIRSF PIRSF002070 131 175 30.0 T 28-03-2018 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 37.853 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 Gene3D G3DSA:2.40.50.140 1 121 1.1E-43 T 28-03-2018 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 Pfam PF00436 Single-strand binding protein family 4 108 6.1E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFA_RS17865 db372bed1810f040f4f0d6d74b0c440b 175 SUPERFAMILY SSF50249 3 175 5.14E-62 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS00420 ecd281058261cf038e8a5972f975daf3 304 SUPERFAMILY SSF161098 87 287 8.24E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00420 ecd281058261cf038e8a5972f975daf3 304 Gene3D G3DSA:1.10.3720.10 20 304 5.8E-40 T 28-03-2018 AFA_RS00420 ecd281058261cf038e8a5972f975daf3 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 5.8E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09690 42fa63e81ed4036c7df4d11bb8bff746 268 Pfam PF10263 SprT-like family 16 117 7.0E-11 T 28-03-2018 IPR006640 SprT-like AFA_RS15145 b2786ff87c8f5c2ba6668cf4dd227b4b 255 Pfam PF00005 ABC transporter 22 169 2.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS15145 b2786ff87c8f5c2ba6668cf4dd227b4b 255 Gene3D G3DSA:3.40.50.300 1 245 6.2E-61 T 28-03-2018 AFA_RS15145 b2786ff87c8f5c2ba6668cf4dd227b4b 255 SMART SM00382 30 218 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15145 b2786ff87c8f5c2ba6668cf4dd227b4b 255 SUPERFAMILY SSF52540 6 237 2.45E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17705 fed750e80fe721700967e00afdb6cb32 399 SUPERFAMILY SSF103473 12 394 1.96E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17705 fed750e80fe721700967e00afdb6cb32 399 Gene3D G3DSA:1.20.1250.20 205 398 9.6E-11 T 28-03-2018 AFA_RS17705 fed750e80fe721700967e00afdb6cb32 399 Pfam PF07690 Major Facilitator Superfamily 24 356 4.5E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS17705 fed750e80fe721700967e00afdb6cb32 399 Gene3D G3DSA:1.20.1250.20 5 204 1.9E-25 T 28-03-2018 AFA_RS17705 fed750e80fe721700967e00afdb6cb32 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 14 389 1.9E-90 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AFA_RS01070 12a7a35419708aff0b4f9d0f582d2b68 234 SUPERFAMILY SSF51419 7 229 3.14E-72 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS01070 12a7a35419708aff0b4f9d0f582d2b68 234 Pfam PF01168 Alanine racemase, N-terminal domain 12 231 1.0E-25 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS01070 12a7a35419708aff0b4f9d0f582d2b68 234 PIRSF PIRSF004848 1 234 1.3E-69 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein AFA_RS01070 12a7a35419708aff0b4f9d0f582d2b68 234 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 11 231 2.3E-51 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein AFA_RS01070 12a7a35419708aff0b4f9d0f582d2b68 234 Gene3D G3DSA:3.20.20.10 1 234 1.3E-67 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 Pfam PF00571 CBS domain 73 130 4.5E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 Pfam PF00571 CBS domain 141 190 2.7E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 SUPERFAMILY SSF54631 68 204 3.54E-29 T 28-03-2018 AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 Gene3D G3DSA:3.10.580.10 52 196 6.4E-34 T 28-03-2018 AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 SUPERFAMILY SSF56176 204 288 8.45E-21 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 SMART SM01091 206 284 7.6E-25 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 Pfam PF03471 Transporter associated domain 209 282 1.8E-18 T 28-03-2018 IPR005170 Transporter-associated domain AFA_RS03205 851c855f14eb622c03728e4c81223cc2 293 Gene3D G3DSA:3.30.465.10 197 284 4.4E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS15055 7172094efeddf0786a8781b0d6103a10 307 SUPERFAMILY SSF103481 49 146 3.92E-9 T 28-03-2018 AFA_RS15055 7172094efeddf0786a8781b0d6103a10 307 Pfam PF00892 EamA-like transporter family 165 299 2.0E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS15055 7172094efeddf0786a8781b0d6103a10 307 Pfam PF00892 EamA-like transporter family 14 146 1.1E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS15055 7172094efeddf0786a8781b0d6103a10 307 SUPERFAMILY SSF103481 206 304 1.44E-10 T 28-03-2018 AFA_RS10530 e4f9e1224f3eba84f005a23f0b1a0d01 402 SUPERFAMILY SSF103473 7 397 6.8E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS10530 e4f9e1224f3eba84f005a23f0b1a0d01 402 Gene3D G3DSA:1.20.1250.20 204 399 3.7E-20 T 28-03-2018 AFA_RS10530 e4f9e1224f3eba84f005a23f0b1a0d01 402 Gene3D G3DSA:1.20.1250.20 8 203 4.8E-15 T 28-03-2018 AFA_RS10530 e4f9e1224f3eba84f005a23f0b1a0d01 402 Pfam PF07690 Major Facilitator Superfamily 28 298 6.9E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS04680 94be703dbc8c9845905dad0e97d9773e 199 SUPERFAMILY SSF52218 1 198 9.3E-64 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS04680 94be703dbc8c9845905dad0e97d9773e 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 197 4.3E-96 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFA_RS04680 94be703dbc8c9845905dad0e97d9773e 199 Pfam PF03358 NADPH-dependent FMN reductase 4 145 1.7E-13 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS04680 94be703dbc8c9845905dad0e97d9773e 199 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 199 42.834 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFA_RS04680 94be703dbc8c9845905dad0e97d9773e 199 Gene3D G3DSA:3.40.50.360 2 199 4.9E-47 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS09400 d40481af3a591bf53a04f46a3b5a1a8f 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 293 5.5E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS09400 d40481af3a591bf53a04f46a3b5a1a8f 309 Gene3D G3DSA:1.10.3470.10 3 298 7.1E-52 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS11830 fbdc5486ebf1838e361e682a4b332157 554 SUPERFAMILY SSF53720 89 522 6.41E-58 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS11830 fbdc5486ebf1838e361e682a4b332157 554 Pfam PF00171 Aldehyde dehydrogenase family 89 492 3.8E-37 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS11830 fbdc5486ebf1838e361e682a4b332157 554 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 2 553 3.1E-274 T 28-03-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 AFA_RS11830 fbdc5486ebf1838e361e682a4b332157 554 Gene3D G3DSA:3.40.309.10 324 521 2.8E-27 T 28-03-2018 AFA_RS11830 fbdc5486ebf1838e361e682a4b332157 554 Gene3D G3DSA:3.40.605.10 84 323 2.3E-34 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS03575 4494d4ab6660850023067eb63ccd177e 446 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 433 2.3E-66 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 SMART SM00895 83 206 2.8E-8 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 Gene3D G3DSA:1.20.120.530 70 216 2.0E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 SMART SM00345 15 73 6.8E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 Gene3D G3DSA:1.10.10.10 1 69 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 SUPERFAMILY SSF46785 8 77 2.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 SUPERFAMILY SSF48008 82 209 7.59E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS03995 309cc91a4fba22cbe3b754b9970b484a 216 Pfam PF07729 FCD domain 84 199 1.9E-14 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 Pfam PF11967 Recombination protein O N terminal 11 81 1.1E-18 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 TIGRFAM TIGR00613 reco: DNA repair protein RecO 13 153 9.6E-17 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 Gene3D G3DSA:2.40.50.140 6 84 1.3E-19 T 28-03-2018 AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 SUPERFAMILY SSF57863 91 150 8.89E-5 T 28-03-2018 AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 Pfam PF02565 Recombination protein O C terminal 88 153 4.8E-14 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFA_RS13050 3e2d7733314e06b775cb78da081597a9 196 SUPERFAMILY SSF50249 9 81 1.35E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 14 355 9.0E-120 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 Pfam PF02601 Exonuclease VII, large subunit 129 439 3.0E-94 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 Gene3D G3DSA:2.40.50.140 13 108 5.0E-4 T 28-03-2018 AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 Pfam PF13742 OB-fold nucleic acid binding domain 13 105 3.0E-26 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 Gene3D G3DSA:3.90.20.10 274 403 8.6E-5 T 28-03-2018 AFA_RS07380 6c674b9b4c95ac4766b1209737ae0024 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 10 442 27.279 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS14335 2351df2987de5bd62904c7d6a6585f70 242 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 36 223 4.7E-56 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFA_RS14335 2351df2987de5bd62904c7d6a6585f70 242 SUPERFAMILY SSF55729 3 230 1.17E-82 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS14335 2351df2987de5bd62904c7d6a6585f70 242 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 34 210 6.1E-70 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFA_RS14335 2351df2987de5bd62904c7d6a6585f70 242 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 242 86.418 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 Gene3D G3DSA:3.40.190.10 89 176 1.0E-12 T 28-03-2018 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 Gene3D G3DSA:3.40.190.10 177 268 2.8E-15 T 28-03-2018 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 SUPERFAMILY SSF46785 6 111 2.72E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 SUPERFAMILY SSF53850 88 294 6.62E-36 T 28-03-2018 AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 Pfam PF03466 LysR substrate binding domain 88 291 2.6E-32 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS07960 64fbb4fc7a7f0d78fa07c9717570815a 304 Gene3D G3DSA:1.10.10.10 2 84 4.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 Gene3D G3DSA:3.30.70.660 106 243 1.4E-40 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 239 1.0E-67 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 34.596 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 Gene3D G3DSA:3.30.70.580 1 105 1.5E-34 T 28-03-2018 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 Pfam PF01416 tRNA pseudouridine synthase 143 245 4.1E-30 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 Pfam PF01416 tRNA pseudouridine synthase 10 103 3.1E-10 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 SUPERFAMILY SSF55120 1 254 2.59E-91 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS10780 9aaf08526d907db4d7521fdc5c939aee 275 PIRSF PIRSF001430 1 255 1.8E-78 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 6.6E-37 T 28-03-2018 IPR023214 HAD-like domain AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 SUPERFAMILY SSF56784 1 217 8.94E-56 T 28-03-2018 IPR023214 HAD-like domain AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 179 1.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 Gene3D G3DSA:3.40.50.1000 75 223 7.0E-32 T 28-03-2018 IPR023214 HAD-like domain AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 Gene3D G3DSA:1.10.150.240 17 74 3.5E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 5 207 1.8E-60 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFA_RS12005 09f4ad75db87abf89a653f623c2e0a4f 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 183 1.0E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 3.4E-74 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82866 796 1021 2.22E-41 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Pfam PF00873 AcrB/AcrD/AcrF family 6 1016 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82714 711 794 8.63E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82693 41 126 2.09E-23 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82693 269 325 3.92E-21 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82693 137 183 3.92E-21 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:1.20.1640.10 282 503 2.6E-46 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:1.20.1640.10 810 1030 3.2E-35 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:3.30.70.1430 41 143 6.9E-26 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:3.30.70.1430 561 657 1.9E-13 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82866 291 491 2.75E-46 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82693 559 656 3.14E-14 T 28-03-2018 AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:3.30.2090.10 710 797 2.5E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 Gene3D G3DSA:3.30.2090.10 182 270 2.8E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS16060 d43c648ee4e22658ee27cf6f7c1f1285 1034 SUPERFAMILY SSF82714 184 267 8.11E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 421 50.979 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 Pfam PF00464 Serine hydroxymethyltransferase 8 386 4.0E-172 T 28-03-2018 AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 SUPERFAMILY SSF53383 4 421 4.64E-175 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 Gene3D G3DSA:3.40.640.10 37 276 3.9E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 PIRSF PIRSF000412 1 426 3.1E-164 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 Gene3D G3DSA:3.90.1150.10 277 420 2.2E-55 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14060 8c8e7800495daf58aab8e6547ba5e364 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFA_RS18135 b8f5b1993b6f1a87d3c0fc453a1968a2 475 Gene3D G3DSA:3.40.309.10 264 458 2.2E-68 T 28-03-2018 AFA_RS18135 b8f5b1993b6f1a87d3c0fc453a1968a2 475 Pfam PF00171 Aldehyde dehydrogenase family 15 472 1.8E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS18135 b8f5b1993b6f1a87d3c0fc453a1968a2 475 Gene3D G3DSA:3.40.605.10 1 263 9.9E-93 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS18135 b8f5b1993b6f1a87d3c0fc453a1968a2 475 SUPERFAMILY SSF53720 2 473 6.94E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 Gene3D G3DSA:1.10.10.10 1 82 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 Gene3D G3DSA:3.40.190.10 85 175 2.1E-17 T 28-03-2018 AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 Gene3D G3DSA:3.40.190.10 176 266 2.0E-13 T 28-03-2018 AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 Pfam PF03466 LysR substrate binding domain 85 280 3.5E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 SUPERFAMILY SSF53850 87 296 3.8E-32 T 28-03-2018 AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 SUPERFAMILY SSF46785 1 83 1.13E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09160 f356301f8b76ae260c333e8f71aac615 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS18520 707660a9ff04e5d2228151eb1bdba493 323 Gene3D G3DSA:3.40.190.10 121 231 7.6E-7 T 28-03-2018 AFA_RS18520 707660a9ff04e5d2228151eb1bdba493 323 PIRSF PIRSF017082 2 323 4.4E-68 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS18520 707660a9ff04e5d2228151eb1bdba493 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 319 4.6E-60 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS18520 707660a9ff04e5d2228151eb1bdba493 323 SUPERFAMILY SSF53850 105 276 1.41E-6 T 28-03-2018 AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 Gene3D G3DSA:3.40.50.300 1 258 5.6E-41 T 28-03-2018 AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 SUPERFAMILY SSF52540 2 231 1.17E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 SMART SM00382 26 238 2.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 Pfam PF00005 ABC transporter 17 172 1.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08775 8d42fcc1231ab396b01363bf32a6da4d 259 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 4.4E-109 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 SUPERFAMILY SSF51182 5 181 1.13E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 Gene3D G3DSA:2.60.120.10 2 93 1.0E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 Gene3D G3DSA:1.10.10.60 147 204 1.6E-9 T 28-03-2018 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 Pfam PF12833 Helix-turn-helix domain 172 248 1.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 SMART SM00342 166 248 6.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 Gene3D G3DSA:1.10.10.60 205 251 2.5E-7 T 28-03-2018 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 Pfam PF02311 AraC-like ligand binding domain 26 92 3.8E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS11435 c7d8ef98dc7d06a4286c1113a7803fca 254 SUPERFAMILY SSF46689 206 250 1.16E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Pfam PF08521 Two-component sensor kinase N-terminal 29 187 1.8E-31 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 SUPERFAMILY SSF55874 328 500 4.98E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Gene3D G3DSA:1.20.5.1040 169 212 0.13 T 28-03-2018 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Gene3D G3DSA:1.20.5.1040 14 63 0.51 T 28-03-2018 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 496 2.5E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Gene3D G3DSA:3.30.565.10 333 507 1.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 SUPERFAMILY SSF47384 248 327 9.02E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 431 7.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 495 7.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 471 7.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 SMART SM00388 265 330 2.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 326 1.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 SMART SM00387 380 498 4.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS14590 fd7c4e668793b9535397f4c607ebc847 507 Gene3D G3DSA:1.10.287.130 257 326 4.5E-10 T 28-03-2018 AFA_RS14795 23cce9bdcc0559dea52b823b03f9194a 233 Gene3D G3DSA:2.60.120.10 11 130 9.2E-44 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS14795 23cce9bdcc0559dea52b823b03f9194a 233 PIRSF PIRSF006232 2 233 8.8E-50 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFA_RS14795 23cce9bdcc0559dea52b823b03f9194a 233 Gene3D G3DSA:2.60.120.10 131 233 3.8E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS14795 23cce9bdcc0559dea52b823b03f9194a 233 Pfam PF02678 Pirin 10 118 5.4E-34 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFA_RS14795 23cce9bdcc0559dea52b823b03f9194a 233 SUPERFAMILY SSF51182 1 230 8.67E-71 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 Pfam PF14559 Tetratricopeptide repeat 142 201 2.2E-10 T 28-03-2018 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 SMART SM00028 129 162 0.033 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 SMART SM00028 163 196 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 Gene3D G3DSA:1.25.40.10 54 142 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 Gene3D G3DSA:1.25.40.10 143 181 4.0E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 SUPERFAMILY SSF48452 73 223 4.11E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13655 71f2a863d14c9a2098bfb547786f43c1 332 Gene3D G3DSA:1.25.40.10 182 274 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 27 135 2.5E-41 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 108 132 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 103 138 6.6E-11 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 SUPERFAMILY SSF109635 8 104 8.5E-27 T 28-03-2018 AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 SUPERFAMILY SSF57716 105 143 3.56E-8 T 28-03-2018 AFA_RS01965 cf3d1d6d5a66bec0b5ea0746415222ea 145 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 23 144 27.109 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AFA_RS02575 b962db9a72f6a918a66f9e38d8b2c9f8 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 10 186 7.0E-46 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 AFA_RS02575 b962db9a72f6a918a66f9e38d8b2c9f8 187 SUPERFAMILY SSF51283 3 186 1.96E-51 T 28-03-2018 IPR029054 dUTPase-like AFA_RS02575 b962db9a72f6a918a66f9e38d8b2c9f8 187 Pfam PF00692 dUTPase 80 183 1.8E-7 T 28-03-2018 IPR029054 dUTPase-like AFA_RS02575 b962db9a72f6a918a66f9e38d8b2c9f8 187 Hamap MF_00146 dCTP deaminase [dcd]. 2 187 27.453 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 AFA_RS02575 b962db9a72f6a918a66f9e38d8b2c9f8 187 Gene3D G3DSA:2.70.40.10 1 160 6.4E-58 T 28-03-2018 AFA_RS16560 477c2379caf5fa8cce165fbbfca43786 381 Gene3D G3DSA:3.40.50.2000 195 357 3.0E-34 T 28-03-2018 AFA_RS16560 477c2379caf5fa8cce165fbbfca43786 381 Pfam PF00534 Glycosyl transferases group 1 198 352 1.2E-23 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS16560 477c2379caf5fa8cce165fbbfca43786 381 Gene3D G3DSA:3.40.50.2000 2 194 1.1E-13 T 28-03-2018 AFA_RS16560 477c2379caf5fa8cce165fbbfca43786 381 SUPERFAMILY SSF53756 21 369 5.71E-61 T 28-03-2018 AFA_RS16560 477c2379caf5fa8cce165fbbfca43786 381 Pfam PF13579 Glycosyl transferase 4-like domain 21 173 2.8E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 1.0E-44 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 SUPERFAMILY SSF118215 8 406 2.75E-113 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 Gene3D G3DSA:1.10.3860.10 1 412 1.2E-116 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS09145 6c30d973be42d702c231e73323a955d7 440 Pfam PF00375 Sodium:dicarboxylate symporter family 8 405 3.1E-112 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS07040 392ed71b089ac1daaedc361cbc431fa8 63 Gene3D G3DSA:1.10.260.40 1 53 9.2E-6 T 28-03-2018 AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 SMART SM00387 323 434 3.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 SUPERFAMILY SSF55874 277 431 1.57E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 Gene3D G3DSA:1.10.287.130 206 281 2.6E-9 T 28-03-2018 AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 SUPERFAMILY SSF47384 199 267 1.69E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 Gene3D G3DSA:3.30.565.10 282 433 1.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11490 52cfa57100696e9ef0359f69abb9c195 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 432 7.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS08130 0daf033dc4efbb8b1ec3b44f5385c472 495 Gene3D G3DSA:2.40.160.60 191 453 3.4E-4 T 28-03-2018 AFA_RS08130 0daf033dc4efbb8b1ec3b44f5385c472 495 Gene3D G3DSA:1.25.20.10 4 176 2.5E-6 T 28-03-2018 AFA_RS08130 0daf033dc4efbb8b1ec3b44f5385c472 495 Pfam PF04575 Protein of unknown function (DUF560) 194 495 4.8E-41 T 28-03-2018 IPR007655 Protein of unknown function DUF560 AFA_RS08130 0daf033dc4efbb8b1ec3b44f5385c472 495 SUPERFAMILY SSF48452 84 166 8.76E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 Pfam PF00890 FAD binding domain 2 34 3.0E-5 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 SUPERFAMILY SSF51905 2 159 2.18E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 SUPERFAMILY SSF51905 256 351 2.18E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 Pfam PF04820 Tryptophan halogenase 88 351 3.1E-6 T 28-03-2018 IPR006905 Flavin-dependent halogenase AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 Gene3D G3DSA:3.50.50.60 2 353 2.3E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 2.1E-8 T 28-03-2018 AFA_RS11335 1cdb475873b8bf771825f3379a1d1217 357 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 1 22 2.1E-8 T 28-03-2018 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 Gene3D G3DSA:3.40.50.2000 22 201 7.6E-5 T 28-03-2018 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 Pfam PF02684 Lipid-A-disaccharide synthetase 27 405 9.1E-89 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 Gene3D G3DSA:3.40.50.2000 202 400 4.0E-15 T 28-03-2018 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 SUPERFAMILY SSF53756 26 414 4.49E-28 T 28-03-2018 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 23 419 34.166 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AFA_RS10145 9914dd5d42144644cd8bb7ba566c9ad0 420 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 25 407 2.1E-90 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 Pfam PF07883 Cupin domain 138 195 2.8E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 SUPERFAMILY SSF47413 8 71 9.57E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 Gene3D G3DSA:1.10.260.40 1 83 1.1E-13 T 28-03-2018 AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 Gene3D G3DSA:2.60.120.10 84 203 1.2E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 SUPERFAMILY SSF51182 99 196 7.36E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 SMART SM00530 15 70 9.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS09000 f2e0164c93cea8a54aeeebb75bc24a94 204 Pfam PF12844 Helix-turn-helix domain 13 72 2.6E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS00805 018f417361fd35cb109ea14ded671d85 206 SUPERFAMILY SSF52499 10 203 1.23E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS00805 018f417361fd35cb109ea14ded671d85 206 Gene3D G3DSA:3.40.50.850 11 206 5.3E-39 T 28-03-2018 AFA_RS00805 018f417361fd35cb109ea14ded671d85 206 Pfam PF00857 Isochorismatase family 22 196 2.0E-31 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS17235 c8e3c58f4c8d663ce0c85c8d5e8db414 280 Gene3D G3DSA:1.10.3720.10 11 273 6.9E-37 T 28-03-2018 AFA_RS17235 c8e3c58f4c8d663ce0c85c8d5e8db414 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 267 4.8E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS17235 c8e3c58f4c8d663ce0c85c8d5e8db414 280 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 266 7.9E-89 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 AFA_RS17235 c8e3c58f4c8d663ce0c85c8d5e8db414 280 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 12 267 1.3E-100 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 AFA_RS17235 c8e3c58f4c8d663ce0c85c8d5e8db414 280 SUPERFAMILY SSF161098 10 259 1.57E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 PIRSF PIRSF000239 1 187 1.3E-56 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 SUPERFAMILY SSF52833 1 186 1.4E-57 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 9.6E-106 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 Gene3D G3DSA:3.30.1020.10 153 183 1.0E-9 T 28-03-2018 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 Gene3D G3DSA:3.40.30.10 5 152 2.4E-33 T 28-03-2018 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 5.4E-5 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS14720 360be7046e718dc38b05c5c8e6480295 187 Pfam PF00578 AhpC/TSA family 9 132 3.3E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 PIRSF PIRSF000103 11 307 1.7E-74 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 Gene3D G3DSA:1.10.1040.10 188 306 4.5E-35 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 Gene3D G3DSA:3.40.50.720 4 187 7.8E-38 T 28-03-2018 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 SUPERFAMILY SSF51735 16 178 3.81E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 SUPERFAMILY SSF48179 178 301 8.62E-40 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 180 299 4.2E-35 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 20 33 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFA_RS14585 4a40d2f6700c2ab1613a45421a5cd7c3 307 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 17 177 1.1E-47 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AFA_RS02065 82694e21d8108549300e9a70295e70a2 189 SUPERFAMILY SSF53335 3 151 9.71E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02065 82694e21d8108549300e9a70295e70a2 189 Gene3D G3DSA:3.40.50.150 3 165 2.5E-20 T 28-03-2018 AFA_RS02065 82694e21d8108549300e9a70295e70a2 189 Pfam PF13649 Methyltransferase domain 24 106 1.7E-9 T 28-03-2018 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 Gene3D G3DSA:3.40.605.10 1 265 3.0E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 SUPERFAMILY SSF53720 4 483 1.28E-143 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 Pfam PF00171 Aldehyde dehydrogenase family 17 479 1.5E-136 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 Gene3D G3DSA:3.40.309.10 266 461 9.2E-64 T 28-03-2018 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 483 1.8E-207 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 AFA_RS12975 ce876a84ec1a5a15c0625fd911e4e279 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS00930 8850edb30a1f5c991bb62790b36b5308 211 SUPERFAMILY SSF159594 34 205 3.66E-34 T 28-03-2018 AFA_RS00930 8850edb30a1f5c991bb62790b36b5308 211 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 36 197 8.2E-18 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component AFA_RS00930 8850edb30a1f5c991bb62790b36b5308 211 Gene3D G3DSA:3.40.50.10610 19 210 2.4E-32 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component AFA_RS06570 ea1f6c8ac190a1afa5618a8f5577692a 138 Gene3D G3DSA:1.20.1290.10 1 136 2.4E-32 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS06570 ea1f6c8ac190a1afa5618a8f5577692a 138 Pfam PF02627 Carboxymuconolactone decarboxylase family 3 85 2.3E-17 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS06570 ea1f6c8ac190a1afa5618a8f5577692a 138 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 22 69 1.5E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS06570 ea1f6c8ac190a1afa5618a8f5577692a 138 SUPERFAMILY SSF69118 2 136 9.86E-41 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS00345 bfae1ec549ca8b56aaafa8acffd24191 429 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 421 3.6E-95 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00345 bfae1ec549ca8b56aaafa8acffd24191 429 PIRSF PIRSF006066 1 429 3.6E-96 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00345 bfae1ec549ca8b56aaafa8acffd24191 429 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 426 6.0E-98 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 SUPERFAMILY SSF54631 221 365 1.21E-30 T 28-03-2018 AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 Pfam PF04982 HPP family 55 171 6.4E-29 T 28-03-2018 IPR007065 HPP AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 Gene3D G3DSA:3.10.580.10 292 370 1.6E-14 T 28-03-2018 AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 Gene3D G3DSA:3.10.580.10 170 285 5.1E-12 T 28-03-2018 AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 Pfam PF00571 CBS domain 311 365 1.1E-12 T 28-03-2018 IPR000644 CBS domain AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 Pfam PF00571 CBS domain 234 283 7.1E-9 T 28-03-2018 IPR000644 CBS domain AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 SMART SM00116 238 286 1.4E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS14300 9f75e50a98f8e16572faed0683f0a007 377 SMART SM00116 318 366 2.7E-4 T 28-03-2018 IPR000644 CBS domain AFA_RS01345 c9e772a50c47a8e03f450b9000a7cfbd 266 Gene3D G3DSA:3.20.20.70 11 261 7.3E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01345 c9e772a50c47a8e03f450b9000a7cfbd 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 AFA_RS01345 c9e772a50c47a8e03f450b9000a7cfbd 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 35.91 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFA_RS01345 c9e772a50c47a8e03f450b9000a7cfbd 266 SUPERFAMILY SSF51366 12 262 5.18E-90 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS01345 c9e772a50c47a8e03f450b9000a7cfbd 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 2.8E-95 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFA_RS04530 3a28df745cae858727ffb8f4faf27231 286 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 11 277 2.5E-66 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFA_RS04530 3a28df745cae858727ffb8f4faf27231 286 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 284 17.424 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFA_RS04530 3a28df745cae858727ffb8f4faf27231 286 Pfam PF02673 Bacitracin resistance protein BacA 11 278 1.8E-78 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFA_RS04695 52dbbc90d35f6573c57ed95f88cff959 205 SUPERFAMILY SSF50486 7 188 1.96E-56 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 AFA_RS04695 52dbbc90d35f6573c57ed95f88cff959 205 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 10 186 29.626 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS04695 52dbbc90d35f6573c57ed95f88cff959 205 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 12 182 3.7E-50 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS04695 52dbbc90d35f6573c57ed95f88cff959 205 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 8 186 2.5E-46 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS04695 52dbbc90d35f6573c57ed95f88cff959 205 Gene3D G3DSA:3.10.300.10 4 194 1.2E-55 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 SMART SM00028 226 259 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 SMART SM00028 155 188 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 Gene3D G3DSA:1.25.40.10 138 282 2.1E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 SUPERFAMILY SSF48452 232 261 8.54E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 SUPERFAMILY SSF48452 141 205 8.54E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02925 3a32c41a86a7e5c8b4dd6d3b61ad1680 291 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 5 118 3.4E-23 T 28-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 158 770 2.3E-104 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 SUPERFAMILY SSF56935 124 784 1.47E-123 T 28-03-2018 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 Gene3D G3DSA:2.170.130.10 116 267 3.3E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 Pfam PF00593 TonB dependent receptor 370 784 1.5E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 SMART SM00965 72 122 1.5E-14 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 Gene3D G3DSA:2.40.170.20 273 786 2.6E-72 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 260 1.1E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS06405 45ae0909242c4ef615e4064e528f3957 787 Pfam PF07660 Secretin and TonB N terminus short domain 72 120 5.5E-13 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 104 7.2E-43 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 PIRSF PIRSF039144 1 112 2.9E-55 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 PRINTS PR00340 P-II protein signature 2 17 5.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 PRINTS PR00340 P-II protein signature 23 41 5.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 PRINTS PR00340 P-II protein signature 52 75 5.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 PRINTS PR00340 P-II protein signature 83 103 5.7E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 SMART SM00938 4 105 2.3E-66 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 Gene3D G3DSA:3.30.70.120 1 109 8.5E-49 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFA_RS10540 78461cb4e684bc5c53d891a601502e6f 112 SUPERFAMILY SSF54913 1 112 2.89E-45 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFA_RS03320 978270ffb2350ca65e24a44eeea4c7e4 436 SUPERFAMILY SSF75304 5 426 1.28E-93 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS03320 978270ffb2350ca65e24a44eeea4c7e4 436 Pfam PF01425 Amidase 26 417 6.9E-64 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS03320 978270ffb2350ca65e24a44eeea4c7e4 436 Gene3D G3DSA:3.90.1300.10 7 431 1.4E-92 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 SMART SM00965 52 102 2.5E-6 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 Gene3D G3DSA:2.170.130.10 114 261 4.0E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 155 791 5.9E-105 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 Pfam PF07715 TonB-dependent Receptor Plug Domain 152 253 1.3E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 Pfam PF00593 TonB dependent receptor 344 789 2.5E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 Gene3D G3DSA:2.40.170.20 262 791 1.3E-83 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16150 865f9df99d9d57f5d55e7949df223e71 791 SUPERFAMILY SSF56935 117 791 2.7E-128 T 28-03-2018 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 SUPERFAMILY SSF52343 205 338 4.19E-39 T 28-03-2018 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Pfam PF00175 Oxidoreductase NAD-binding domain 213 319 2.5E-22 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Gene3D G3DSA:3.10.20.30 1 102 4.4E-24 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Gene3D G3DSA:3.40.50.80 204 340 3.5E-26 T 28-03-2018 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 81 1.7E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 2.5E-21 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 SUPERFAMILY SSF63380 102 203 4.12E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 SUPERFAMILY SSF54292 1 92 1.01E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Gene3D G3DSA:2.40.30.10 103 203 1.0E-18 T 28-03-2018 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 Pfam PF00970 Oxidoreductase FAD-binding domain 107 201 5.4E-12 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 2.0E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 2.0E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 2.0E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 2.0E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS11670 973c9cc497d2fe4c34aaeb89421344ca 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 237 246 2.0E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 Gene3D G3DSA:1.10.10.60 297 342 6.4E-10 T 28-03-2018 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 SUPERFAMILY SSF46689 245 295 2.93E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 SUPERFAMILY SSF46689 297 342 2.06E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 Gene3D G3DSA:1.10.10.60 240 296 3.2E-9 T 28-03-2018 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 Pfam PF12833 Helix-turn-helix domain 267 342 9.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS13840 9a5a0441eab24737454930817eb96a11 343 SMART SM00342 261 343 4.0E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS12150 d41c317f8b724b8226a25a1d612e5773 817 SUPERFAMILY SSF52540 378 749 2.67E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12150 d41c317f8b724b8226a25a1d612e5773 817 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 174 378 1.7E-28 T 28-03-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 AFA_RS12150 d41c317f8b724b8226a25a1d612e5773 817 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 6 801 4.2E-196 T 28-03-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 AFA_RS12150 d41c317f8b724b8226a25a1d612e5773 817 Gene3D G3DSA:3.40.50.300 270 785 3.5E-18 T 28-03-2018 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 SUPERFAMILY SSF53706 37 196 1.05E-51 T 28-03-2018 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 104 7.6E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 Gene3D G3DSA:2.20.25.90 37 109 1.8E-21 T 28-03-2018 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 Pfam PF00384 Molybdopterin oxidoreductase 108 168 8.7E-7 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 Gene3D G3DSA:3.40.50.740 110 196 2.1E-11 T 28-03-2018 AFA_RS16820 47a3eb17b53550353bc1277d09f49f12 196 SMART SM00926 44 105 8.5E-22 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS09245 43665cd55a1a884de0d384a262f6d6fd 287 Gene3D G3DSA:3.40.50.1820 21 284 2.6E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09245 43665cd55a1a884de0d384a262f6d6fd 287 SUPERFAMILY SSF53474 13 263 1.63E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09245 43665cd55a1a884de0d384a262f6d6fd 287 Pfam PF07859 alpha/beta hydrolase fold 72 253 1.8E-20 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 AFA_RS00240 c70d188848224b56d0ac01d7828baba4 327 PIRSF PIRSF017082 1 326 9.5E-66 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00240 c70d188848224b56d0ac01d7828baba4 327 SUPERFAMILY SSF53850 113 286 5.84E-9 T 28-03-2018 AFA_RS00240 c70d188848224b56d0ac01d7828baba4 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 323 1.8E-62 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00240 c70d188848224b56d0ac01d7828baba4 327 Gene3D G3DSA:3.40.190.10 128 257 2.4E-12 T 28-03-2018 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 SUPERFAMILY SSF46785 7 141 4.01E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 Gene3D G3DSA:1.10.10.10 5 150 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 Pfam PF01047 MarR family 48 91 5.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 SMART SM00347 26 127 1.3E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS06495 5cec1b044aa807e134de0b7005144a16 154 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 Gene3D G3DSA:1.10.10.60 166 227 1.1E-12 T 28-03-2018 AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 SUPERFAMILY SSF46689 159 223 3.58E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 SUPERFAMILY SSF52172 1 130 1.11E-38 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 Pfam PF00072 Response regulator receiver domain 4 114 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 Gene3D G3DSA:3.40.50.2300 1 123 2.0E-32 T 28-03-2018 AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 SMART SM00448 2 114 3.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16475 7ff2b1fdd6c7258408f0c48f83bfe602 231 Pfam PF02954 Bacterial regulatory protein, Fis family 180 220 1.6E-4 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 SUPERFAMILY SSF52540 129 340 4.36E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 463 6.8E-166 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 ProSitePatterns PS01008 DnaA protein signature. 423 442 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Pfam PF00308 Bacterial dnaA protein 129 346 2.7E-87 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Gene3D G3DSA:3.40.50.300 126 293 2.6E-22 T 28-03-2018 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Gene3D G3DSA:1.10.1750.10 368 464 6.2E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 464 31.618 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 SMART SM00382 161 295 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Gene3D G3DSA:1.10.8.60 295 367 3.3E-24 T 28-03-2018 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 194 208 3.4E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 226 240 3.4E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 260 287 3.4E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 162 182 3.4E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 423 442 3.4E-49 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 SMART SM00760 373 442 1.5E-42 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 SUPERFAMILY SSF48295 361 464 6.54E-36 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Pfam PF11638 DnaA N-terminal domain 2 66 7.9E-19 T 28-03-2018 IPR024633 DnaA N-terminal domain AFA_RS00005 13429133ea13dbf4cb03a1848f49ceef 465 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 374 442 1.9E-31 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 Gene3D G3DSA:3.40.50.300 4 260 9.4E-75 T 28-03-2018 AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 9 258 3.9E-119 T 28-03-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 SMART SM00382 33 231 3.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 PIRSF PIRSF039085 5 259 3.2E-108 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 Pfam PF00005 ABC transporter 24 182 5.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS12600 ab0d5dbda86a5d4cb02511845b8cd4e5 261 SUPERFAMILY SSF52540 8 253 3.99E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16155 5bcce287720f2df1523bc2877752e07f 325 PIRSF PIRSF018266 1 322 7.2E-53 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS16155 5bcce287720f2df1523bc2877752e07f 325 Pfam PF04773 FecR protein 114 204 5.3E-16 T 28-03-2018 IPR006860 FecR protein AFA_RS16155 5bcce287720f2df1523bc2877752e07f 325 Pfam PF16220 Domain of unknown function (DUF4880) 8 51 3.0E-9 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS09570 c38c26d61fef71a5eb2be1ae87a4fa69 260 Pfam PF14348 Domain of unknown function (DUF4400) 50 257 8.3E-47 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type AFA_RS09570 c38c26d61fef71a5eb2be1ae87a4fa69 260 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 15 260 1.1E-42 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 SUPERFAMILY SSF55874 5 201 5.63E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Gene3D G3DSA:3.30.565.10 6 201 2.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 SUPERFAMILY SSF118116 430 620 2.88E-60 T 28-03-2018 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 SUPERFAMILY SSF54211 191 326 1.25E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 618 26.659 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 128 6.1E-11 T 28-03-2018 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 6 306 1.4E-88 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Pfam PF08676 MutL C terminal dimerisation domain 431 578 5.6E-49 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 325 4.9E-36 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 SMART SM01340 208 326 2.8E-51 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 Gene3D G3DSA:3.30.230.10 213 325 4.1E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS03925 ceded61b100775dbdc136cd674be81de 622 SMART SM00853 435 578 2.0E-53 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 PRINTS PR00406 Cytochrome B5 reductase signature 229 237 6.6E-5 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 PRINTS PR00406 Cytochrome B5 reductase signature 112 126 6.6E-5 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 PRINTS PR00406 Cytochrome B5 reductase signature 135 154 6.6E-5 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Gene3D G3DSA:3.10.20.30 261 400 1.7E-25 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Pfam PF00175 Oxidoreductase NAD-binding domain 136 240 9.8E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 SUPERFAMILY SSF54292 304 399 2.49E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 SUPERFAMILY SSF52343 127 264 4.85E-36 T 28-03-2018 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Pfam PF00970 Oxidoreductase FAD-binding domain 46 124 9.0E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 327 391 6.2E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 SUPERFAMILY SSF63380 15 128 1.12E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Gene3D G3DSA:2.40.30.10 15 124 1.1E-22 T 28-03-2018 AFA_RS17730 9b527301a4501547837db57820ee9f24 400 Gene3D G3DSA:3.40.50.80 125 260 3.9E-26 T 28-03-2018 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 Gene3D G3DSA:3.40.190.10 24 158 1.3E-29 T 28-03-2018 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 Gene3D G3DSA:3.40.190.10 159 339 1.6E-24 T 28-03-2018 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 PIRSF PIRSF002756 4 339 9.6E-110 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 SUPERFAMILY SSF53850 27 334 2.72E-94 T 28-03-2018 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 335 1.2E-123 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFA_RS04200 a787e050235d9b90375021481e0596c3 347 Pfam PF12849 PBP superfamily domain 19 306 2.8E-63 T 28-03-2018 IPR024370 PBP domain AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 Gene3D G3DSA:3.20.20.70 1 483 1.2E-121 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 4.8E-165 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SMART SM00116 95 142 2.5E-12 T 28-03-2018 IPR000644 CBS domain AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SMART SM00116 156 204 3.1E-6 T 28-03-2018 IPR000644 CBS domain AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SUPERFAMILY SSF51412 215 476 1.7E-127 T 28-03-2018 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SUPERFAMILY SSF51412 2 89 1.7E-127 T 28-03-2018 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 1.8E-192 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 87.236 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 PIRSF PIRSF000130 1 486 2.8E-206 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 Pfam PF00571 CBS domain 95 138 3.1E-11 T 28-03-2018 IPR000644 CBS domain AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 Pfam PF00571 CBS domain 148 201 5.8E-5 T 28-03-2018 IPR000644 CBS domain AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SUPERFAMILY SSF54631 94 201 1.77E-28 T 28-03-2018 AFA_RS07830 2440d7b01f10528c4b1c1c41b89f1cd1 486 SMART SM01240 6 472 0.0 T 28-03-2018 AFA_RS10710 ce50197200c6e16f9ef5ad6ea63aa3c8 333 SUPERFAMILY SSF53659 3 329 1.27E-82 T 28-03-2018 AFA_RS10710 ce50197200c6e16f9ef5ad6ea63aa3c8 333 Gene3D G3DSA:3.40.50.10750 142 302 3.3E-55 T 28-03-2018 AFA_RS10710 ce50197200c6e16f9ef5ad6ea63aa3c8 333 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 325 2.2E-100 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS10710 ce50197200c6e16f9ef5ad6ea63aa3c8 333 PIRSF PIRSF000428 1 333 5.4E-102 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS10710 ce50197200c6e16f9ef5ad6ea63aa3c8 333 Pfam PF01515 Phosphate acetyl/butaryl transferase 3 326 6.9E-110 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 SUPERFAMILY SSF53850 93 300 2.95E-46 T 28-03-2018 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 SUPERFAMILY SSF46785 4 114 1.66E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 Gene3D G3DSA:1.10.10.10 2 86 7.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 Pfam PF03466 LysR substrate binding domain 91 294 9.7E-46 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.3E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 Gene3D G3DSA:3.40.190.10 95 179 3.2E-16 T 28-03-2018 AFA_RS14790 e8f8af70ed061d95d2d2a4b72f6d7690 305 Gene3D G3DSA:3.40.190.10 180 266 5.6E-23 T 28-03-2018 AFA_RS15990 e16d2778e2d797442dcc154b5931212c 449 Pfam PF01593 Flavin containing amine oxidoreductase 11 312 2.5E-19 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFA_RS15990 e16d2778e2d797442dcc154b5931212c 449 Gene3D G3DSA:3.50.50.60 2 439 1.4E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15990 e16d2778e2d797442dcc154b5931212c 449 SUPERFAMILY SSF51905 3 314 8.42E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15990 e16d2778e2d797442dcc154b5931212c 449 SUPERFAMILY SSF51905 397 428 8.42E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 Pfam PF07549 SecD/SecF GG Motif 33 59 4.8E-8 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 SUPERFAMILY SSF82866 74 294 2.62E-38 T 28-03-2018 AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 28.096 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 4.9E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 4.9E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 4.9E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 4.9E-25 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 94 280 1.0E-49 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 6.7E-76 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 Gene3D G3DSA:1.20.1640.10 86 303 9.7E-31 T 28-03-2018 AFA_RS03235 f06db2721482ba47283c6df849c0565b 312 Pfam PF02355 Protein export membrane protein 107 291 2.1E-62 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 2.7E-12 T 28-03-2018 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 2.7E-12 T 28-03-2018 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 2.7E-12 T 28-03-2018 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 2.7E-12 T 28-03-2018 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 SUPERFAMILY SSF53383 1 385 2.15E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 Pfam PF00155 Aminotransferase class I and II 32 379 1.5E-62 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 Gene3D G3DSA:3.90.1150.10 265 386 5.5E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS03355 a8e8feafd8ceb4aadbaa31f267e14954 386 Gene3D G3DSA:3.40.640.10 46 264 5.8E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS02480 532208dae364ad2d406c580908c7dbd7 69 Gene3D G3DSA:1.10.10.10 3 24 2.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02480 532208dae364ad2d406c580908c7dbd7 69 SMART SM00530 4 59 2.5E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS02480 532208dae364ad2d406c580908c7dbd7 69 Pfam PF01381 Helix-turn-helix 5 59 9.8E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS02480 532208dae364ad2d406c580908c7dbd7 69 SUPERFAMILY SSF47413 3 63 1.26E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS02480 532208dae364ad2d406c580908c7dbd7 69 Gene3D G3DSA:3.30.1190.10 25 65 1.3E-13 T 28-03-2018 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 162 1.4E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 SUPERFAMILY SSF88659 89 164 7.66E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 Pfam PF08281 Sigma-70, region 4 106 158 6.8E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 Gene3D G3DSA:1.10.10.10 100 168 8.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 Gene3D G3DSA:1.10.1740.10 5 75 4.2E-7 T 28-03-2018 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 Pfam PF04542 Sigma-70 region 2 15 73 1.5E-4 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06415 64f79197a7258b295baf5c15c5eb4a8d 168 SUPERFAMILY SSF88946 12 88 6.28E-7 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 SUPERFAMILY SSF69065 3 156 8.11E-48 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 SUPERFAMILY SSF54768 107 222 3.14E-25 T 28-03-2018 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 Pfam PF14622 Ribonuclease-III-like 19 136 3.1E-36 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 SMART SM00535 19 147 1.3E-51 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 Pfam PF00035 Double-stranded RNA binding motif 154 221 3.6E-9 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 ProSitePatterns PS00517 Ribonuclease III family signature. 36 44 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 Gene3D G3DSA:3.30.160.20 149 232 1.3E-17 T 28-03-2018 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 219 5.3E-69 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 218 29.053 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 Gene3D G3DSA:1.10.1520.10 1 148 1.8E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AFA_RS13060 6817852c18441a8c365b75603008d6f9 252 SMART SM00358 154 222 2.5E-16 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 PIRSF PIRSF001435 1 211 7.2E-50 T 28-03-2018 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 1.7E-20 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Gene3D G3DSA:1.10.340.30 19 117 3.2E-23 T 28-03-2018 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Pfam PF00633 Helix-hairpin-helix motif 100 127 9.3E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 SMART SM00525 186 206 1.6E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.525 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 TIGRFAM TIGR01083 nth: endonuclease III 5 194 6.0E-84 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 9.2E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 SUPERFAMILY SSF48150 4 206 6.75E-70 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 Gene3D G3DSA:1.10.1670.10 118 211 3.1E-29 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFA_RS13225 7b5a5292814e60a2dfc60f67cc5e1244 212 SMART SM00478 38 185 9.3E-57 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 Gene3D G3DSA:3.30.930.10 3 327 1.7E-73 T 28-03-2018 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 425 31.857 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 PIRSF PIRSF001549 4 427 8.5E-115 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 Gene3D G3DSA:3.40.50.800 328 425 1.8E-17 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 Pfam PF03129 Anticodon binding domain 333 425 7.8E-11 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 SUPERFAMILY SSF55681 9 319 3.45E-97 T 28-03-2018 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 406 3.6E-150 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 SUPERFAMILY SSF52954 329 426 2.29E-19 T 28-03-2018 IPR004154 Anticodon-binding AFA_RS11565 9e1e9f2adfa11798504a16b5aa09b556 427 Pfam PF13393 Histidyl-tRNA synthetase 13 315 1.0E-46 T 28-03-2018 AFA_RS14145 55ef19f22cffc1ea9de0594db4941289 286 Pfam PF00892 EamA-like transporter family 148 281 1.5E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS14145 55ef19f22cffc1ea9de0594db4941289 286 Pfam PF00892 EamA-like transporter family 12 136 1.2E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS14145 55ef19f22cffc1ea9de0594db4941289 286 SUPERFAMILY SSF103481 192 283 3.66E-11 T 28-03-2018 AFA_RS14145 55ef19f22cffc1ea9de0594db4941289 286 SUPERFAMILY SSF103481 41 139 2.62E-7 T 28-03-2018 AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 Pfam PF01928 CYTH domain 3 185 2.0E-18 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 SMART SM00880 247 497 1.7E-16 T 28-03-2018 IPR007899 CHAD domain AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 SMART SM01118 1 193 2.2E-18 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 SUPERFAMILY SSF55154 2 209 1.32E-33 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 Pfam PF05235 CHAD domain 265 462 8.5E-22 T 28-03-2018 IPR007899 CHAD domain AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 80 0.005 T 28-03-2018 AFA_RS14885 48d5439a0f3d198efe079844d496ce57 509 Gene3D G3DSA:2.40.320.10 1 200 5.7E-32 T 28-03-2018 AFA_RS16885 c700b808b791add43556a8d67c7d2409 362 SUPERFAMILY SSF52151 36 103 3.4E-10 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS16885 c700b808b791add43556a8d67c7d2409 362 SUPERFAMILY SSF52151 146 332 3.4E-10 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 SUPERFAMILY SSF48008 80 218 5.49E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 Pfam PF07729 FCD domain 85 212 4.7E-16 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 Gene3D G3DSA:1.20.120.530 77 223 1.5E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 SUPERFAMILY SSF46785 9 78 2.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 SMART SM00345 16 74 3.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 4.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 SMART SM00895 84 213 3.8E-10 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS13795 10944a2383bce6f537d354a3a6f62125 223 Gene3D G3DSA:1.10.10.10 1 76 5.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08785 97327b5db4b50b444af209c704b91e7b 415 Gene3D G3DSA:3.40.640.10 41 289 6.3E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS08785 97327b5db4b50b444af209c704b91e7b 415 Gene3D G3DSA:3.90.1150.10 290 408 2.8E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS08785 97327b5db4b50b444af209c704b91e7b 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 15 413 7.0E-176 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 AFA_RS08785 97327b5db4b50b444af209c704b91e7b 415 SUPERFAMILY SSF53383 15 409 3.73E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS08785 97327b5db4b50b444af209c704b91e7b 415 Pfam PF00266 Aminotransferase class-V 33 401 1.9E-144 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS13080 00c322d47d72bcc7dc47def132f8e016 336 PIRSF PIRSF005427 3 333 6.4E-83 T 28-03-2018 IPR005588 MucB/RseB AFA_RS13080 00c322d47d72bcc7dc47def132f8e016 336 Pfam PF03888 MucB/RseB N-terminal domain 41 212 9.7E-55 T 28-03-2018 IPR033434 MucB/RseB, N-terminal AFA_RS13080 00c322d47d72bcc7dc47def132f8e016 336 Gene3D G3DSA:2.50.20.10 41 224 6.1E-18 T 28-03-2018 AFA_RS13080 00c322d47d72bcc7dc47def132f8e016 336 Pfam PF17188 MucB/RseB C-terminal domain 233 326 5.3E-18 T 28-03-2018 IPR033436 MucB/RseB, C-terminal AFA_RS15755 4aeedb78236bdcaf3e1c17fc6a3edd3c 53 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 6.0E-15 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 AFA_RS15755 4aeedb78236bdcaf3e1c17fc6a3edd3c 53 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 50 19.525 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 AFA_RS15755 4aeedb78236bdcaf3e1c17fc6a3edd3c 53 PIRSF PIRSF036466 1 53 1.2E-20 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 AFA_RS09995 ccfbfb654c421fbd6877b985093ae1a1 133 SUPERFAMILY SSF55729 21 126 2.19E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS09995 ccfbfb654c421fbd6877b985093ae1a1 133 Gene3D G3DSA:3.40.630.30 1 132 1.6E-21 T 28-03-2018 AFA_RS09995 ccfbfb654c421fbd6877b985093ae1a1 133 Pfam PF00583 Acetyltransferase (GNAT) family 20 122 2.5E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS05035 1c3d5233f81fac9f4ca8cf368c464ad1 705 Gene3D G3DSA:2.160.20.10 190 621 1.3E-4 T 28-03-2018 IPR012334 Pectin lyase fold AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Gene3D G3DSA:1.20.200.10 140 416 4.6E-88 T 28-03-2018 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Gene3D G3DSA:1.10.275.10 2 139 3.6E-61 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal AFA_RS09450 416a5c3467cb624592d98685792b828d 465 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 5.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 5.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 5.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 5.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Pfam PF00206 Lyase 12 344 1.3E-110 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal AFA_RS09450 416a5c3467cb624592d98685792b828d 465 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 5 461 8.9E-219 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Pfam PF10415 Fumarase C C-terminus 410 463 1.1E-23 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Gene3D G3DSA:1.10.40.30 417 464 4.8E-26 T 28-03-2018 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 8.3E-7 T 28-03-2018 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 8.3E-7 T 28-03-2018 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 8.3E-7 T 28-03-2018 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 464 88.75 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFA_RS09450 416a5c3467cb624592d98685792b828d 465 SUPERFAMILY SSF48557 4 462 3.24E-154 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 AFA_RS06325 954634035ea1f4e372dd5237b8bf97b7 245 Gene3D G3DSA:1.20.58.430 27 220 2.9E-34 T 28-03-2018 AFA_RS06325 954634035ea1f4e372dd5237b8bf97b7 245 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 5 243 4.5E-76 T 28-03-2018 IPR014147 Type IV conjugative transfer protein TrbJ AFA_RS06325 954634035ea1f4e372dd5237b8bf97b7 245 SUPERFAMILY SSF101082 27 207 9.02E-5 T 28-03-2018 IPR023220 Type IV secretion system, VirB5-domain AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 Gene3D G3DSA:3.40.50.720 1 246 8.5E-67 T 28-03-2018 AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 SUPERFAMILY SSF51735 1 242 9.06E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 7.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 7.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 7.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 6.7E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 1.3E-46 T 28-03-2018 AFA_RS10350 46c47b904e28f1bbfa40696e3369f63b 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 SUPERFAMILY SSF89550 16 71 4.45E-7 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Gene3D G3DSA:2.40.50.140 891 1056 1.8E-5 T 28-03-2018 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 SMART SM00481 10 80 1.0E-7 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Pfam PF14579 Helix-hairpin-helix motif 805 896 2.5E-12 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Gene3D G3DSA:3.20.20.140 7 262 1.0E-27 T 28-03-2018 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Pfam PF02811 PHP domain 15 146 2.8E-13 T 28-03-2018 IPR004013 PHP domain GO:0003824 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 9 1065 12.884 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 308 731 3.1E-143 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS09045 0ecd57a9f3d318c28b3028ed5e3b9800 1065 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 11 856 4.5E-159 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 PIRSF PIRSF016184 1 261 3.7E-54 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 Gene3D G3DSA:3.10.310.10 124 249 2.8E-29 T 28-03-2018 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 217 6.4E-37 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 Pfam PF02567 Phenazine biosynthesis-like protein 8 257 6.1E-60 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 Gene3D G3DSA:3.10.310.10 1 123 7.3E-34 T 28-03-2018 AFA_RS18460 8c07901cd535bd9158d2dc320717f529 262 SUPERFAMILY SSF54506 1 260 1.05E-81 T 28-03-2018 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 18 72 3.8E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 Gene3D G3DSA:1.10.287.1040 16 79 1.2E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 18 78 14.543 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 Pfam PF02609 Exonuclease VII small subunit 19 69 1.2E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 PIRSF PIRSF006488 7 87 1.4E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 SUPERFAMILY SSF116842 12 78 8.37E-19 T 28-03-2018 AFA_RS05175 0f0ed387d6eb9baf994fa19a98ff6ac7 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 19 58 2.0E-9 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 Hamap MF_01830 UPF0317 protein . 12 266 53.328 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 SUPERFAMILY SSF160920 13 259 3.14E-110 T 28-03-2018 AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 Gene3D G3DSA:3.40.1640.10 3 166 7.9E-63 T 28-03-2018 AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 Gene3D G3DSA:3.40.1640.10 204 267 2.8E-9 T 28-03-2018 AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 Pfam PF07286 Protein of unknown function (DUF1445) 116 258 5.4E-63 T 28-03-2018 IPR009906 D-glutamate cyclase AFA_RS01180 cf1052613a26cd5ee50e2028a738f0a3 267 PIRSF PIRSF029755 3 267 9.8E-120 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 SUPERFAMILY SSF46785 5 94 7.16E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.4E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 Gene3D G3DSA:1.10.10.10 1 97 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 Pfam PF12840 Helix-turn-helix domain 10 69 4.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15400 90f57d29b471c3be0e634559bda01f99 107 SMART SM00418 8 89 1.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS13345 cd973919afa53707b275d6f289cef273 371 Gene3D G3DSA:3.20.20.70 6 366 3.8E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS13345 cd973919afa53707b275d6f289cef273 371 Pfam PF03060 Nitronate monooxygenase 8 349 3.1E-79 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFA_RS13345 cd973919afa53707b275d6f289cef273 371 SUPERFAMILY SSF51412 8 335 2.75E-67 T 28-03-2018 AFA_RS01715 c1859f962fec44dbf512d7fb585ce355 213 Pfam PF13098 Thioredoxin-like domain 77 175 4.5E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS01715 c1859f962fec44dbf512d7fb585ce355 213 Gene3D G3DSA:3.40.30.10 35 212 1.1E-16 T 28-03-2018 AFA_RS01715 c1859f962fec44dbf512d7fb585ce355 213 TIGRFAM TIGR02661 MauD: methylamine dehydrogenase accessory protein MauD 4 191 2.9E-63 T 28-03-2018 IPR013478 Methylamine dehydrogenase accessory protein MauD GO:0030416 AFA_RS01715 c1859f962fec44dbf512d7fb585ce355 213 SUPERFAMILY SSF52833 46 168 8.23E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS16305 7dc06d14bdd5af75ab44c001d978aee5 46 Pfam PF08173 Membrane bound YbgT-like protein 1 27 4.9E-16 T 28-03-2018 IPR012994 Membrane bound YbgT-like AFA_RS16305 7dc06d14bdd5af75ab44c001d978aee5 46 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 1.7E-19 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 Pfam PF00375 Sodium:dicarboxylate symporter family 23 415 2.6E-105 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 309 332 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 50 65 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 PRINTS PR00173 Glutamate-aspartate symporter signature 306 332 1.7E-25 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 1.7E-25 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 PRINTS PR00173 Glutamate-aspartate symporter signature 159 181 1.7E-25 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 1.7E-25 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 PRINTS PR00173 Glutamate-aspartate symporter signature 341 360 1.7E-25 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 Gene3D G3DSA:1.10.3860.10 13 422 2.8E-113 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 16 442 37.618 T 28-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 AFA_RS15230 7b2837aa6968d2dd85fb19d5fbbf18ff 463 SUPERFAMILY SSF118215 23 416 8.11E-115 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS03555 61b506576f9620078f5c01060cd2c8ef 92 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 1.4E-24 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFA_RS03555 61b506576f9620078f5c01060cd2c8ef 92 SUPERFAMILY SSF55229 34 84 3.66E-15 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFA_RS03555 61b506576f9620078f5c01060cd2c8ef 92 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 1.3E-29 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFA_RS03555 61b506576f9620078f5c01060cd2c8ef 92 Gene3D G3DSA:3.30.1070.10 1 83 2.2E-27 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFA_RS03555 61b506576f9620078f5c01060cd2c8ef 92 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 91 18.314 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 Gene3D G3DSA:1.10.1740.10 2 69 6.0E-16 T 28-03-2018 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 Pfam PF08281 Sigma-70, region 4 104 153 6.2E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 Pfam PF04542 Sigma-70 region 2 9 73 9.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 SUPERFAMILY SSF88659 86 154 3.6E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 Gene3D G3DSA:1.10.10.10 70 159 8.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 SUPERFAMILY SSF88946 6 84 1.37E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06135 311d1f8d7fa299a1a92291c559d2d4ca 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 153 1.6E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS07300 d1216eab430022007271275bbbfd3bf1 224 Pfam PF02669 K+-transporting ATPase, c chain 21 214 1.3E-68 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFA_RS07300 d1216eab430022007271275bbbfd3bf1 224 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 17 216 32.532 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFA_RS07300 d1216eab430022007271275bbbfd3bf1 224 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 20 214 2.0E-66 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFA_RS07300 d1216eab430022007271275bbbfd3bf1 224 PIRSF PIRSF001296 16 220 8.5E-71 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFA_RS07815 4f57936102fbfc64becbf3e906563646 282 Gene3D G3DSA:3.20.20.140 7 264 7.4E-44 T 28-03-2018 AFA_RS07815 4f57936102fbfc64becbf3e906563646 282 Pfam PF02811 PHP domain 10 163 8.4E-7 T 28-03-2018 IPR004013 PHP domain GO:0003824 AFA_RS07815 4f57936102fbfc64becbf3e906563646 282 SMART SM00481 9 74 2.2E-13 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFA_RS07815 4f57936102fbfc64becbf3e906563646 282 SUPERFAMILY SSF89550 170 281 1.18E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFA_RS07815 4f57936102fbfc64becbf3e906563646 282 SUPERFAMILY SSF89550 8 87 1.18E-46 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 Gene3D G3DSA:3.60.120.10 22 368 2.2E-111 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 Pfam PF00425 chorismate binding enzyme 104 359 2.4E-89 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 SUPERFAMILY SSF56322 33 365 1.02E-106 T 28-03-2018 IPR005801 ADC synthase GO:0009058 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 PRINTS PR00095 Anthranilate synthase component I signature 220 233 1.1E-15 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 PRINTS PR00095 Anthranilate synthase component I signature 300 314 1.1E-15 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 PRINTS PR00095 Anthranilate synthase component I signature 206 219 1.1E-15 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 PRINTS PR00095 Anthranilate synthase component I signature 315 329 1.1E-15 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS03515 4a4495964a36c393763c9d382e7d041e 370 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 83 363 1.7E-109 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 237 1.6E-86 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 1.3E-43 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 SUPERFAMILY SSF53790 1 240 3.79E-73 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 Gene3D G3DSA:3.40.1010.10 2 127 1.1E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS11220 5d275ad4a517f09f903b25833632140f 260 Gene3D G3DSA:3.30.950.10 128 255 8.5E-34 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AFA_RS16865 d62cf711ef0bf02550dc68d418eacf50 260 Gene3D G3DSA:3.40.225.10 27 255 9.7E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS16865 d62cf711ef0bf02550dc68d418eacf50 260 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 34 211 3.2E-37 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS16865 d62cf711ef0bf02550dc68d418eacf50 260 SMART SM01007 33 211 3.1E-43 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS16865 d62cf711ef0bf02550dc68d418eacf50 260 SUPERFAMILY SSF53639 26 234 5.49E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS01680 18bd387cf3998fbd4a92099c1bdf6aab 222 SUPERFAMILY SSF161098 17 205 2.49E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01680 18bd387cf3998fbd4a92099c1bdf6aab 222 Gene3D G3DSA:1.10.3720.10 5 220 1.4E-42 T 28-03-2018 AFA_RS01680 18bd387cf3998fbd4a92099c1bdf6aab 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 114 6.3E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS01680 18bd387cf3998fbd4a92099c1bdf6aab 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 204 3.4E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09560 681cff98a444250c904e83ade0f424f4 183 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 57 164 6.0E-20 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 AFA_RS09560 681cff98a444250c904e83ade0f424f4 183 Pfam PF11072 Protein of unknown function (DUF2859) 51 164 6.1E-23 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 AFA_RS11040 69c8025a29d813f10eb821871a024053 264 Gene3D G3DSA:3.90.226.10 3 204 5.6E-49 T 28-03-2018 AFA_RS11040 69c8025a29d813f10eb821871a024053 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AFA_RS11040 69c8025a29d813f10eb821871a024053 264 Gene3D G3DSA:1.10.12.10 208 248 7.9E-19 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS11040 69c8025a29d813f10eb821871a024053 264 SUPERFAMILY SSF52096 8 262 1.8E-56 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS11040 69c8025a29d813f10eb821871a024053 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 256 3.2E-29 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 Gene3D G3DSA:2.40.50.100 5 124 1.0E-35 T 28-03-2018 AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 33.192 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 122 3.8E-35 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 SUPERFAMILY SSF51230 2 122 5.89E-35 T 28-03-2018 IPR011053 Single hybrid motif AFA_RS02590 10c85ee6bb425998c426bfaf7985b9e6 124 Pfam PF01597 Glycine cleavage H-protein 7 122 1.4E-36 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFA_RS06400 12b0d82e967bbe6ec2d5212a34abaccc 222 SUPERFAMILY SSF56300 12 215 6.33E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS06400 12b0d82e967bbe6ec2d5212a34abaccc 222 Gene3D G3DSA:3.60.21.10 7 219 7.7E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS06400 12b0d82e967bbe6ec2d5212a34abaccc 222 Pfam PF00149 Calcineurin-like phosphoesterase 16 185 2.8E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS13875 96247ad6757cba0dc1447275d7757d62 320 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 313 2.0E-72 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS13875 96247ad6757cba0dc1447275d7757d62 320 Gene3D G3DSA:3.40.50.720 136 294 8.4E-37 T 28-03-2018 AFA_RS13875 96247ad6757cba0dc1447275d7757d62 320 Gene3D G3DSA:3.30.1780.10 1 135 8.0E-37 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFA_RS13875 96247ad6757cba0dc1447275d7757d62 320 SUPERFAMILY SSF51735 1 313 9.88E-97 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13875 96247ad6757cba0dc1447275d7757d62 320 PIRSF PIRSF001439 1 317 2.5E-77 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS15455 8a493bdcb81db4d483fb0d4907388ce8 168 SUPERFAMILY SSF55729 8 155 2.66E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS15455 8a493bdcb81db4d483fb0d4907388ce8 168 Gene3D G3DSA:3.40.630.30 5 162 8.3E-24 T 28-03-2018 AFA_RS15455 8a493bdcb81db4d483fb0d4907388ce8 168 Pfam PF00583 Acetyltransferase (GNAT) family 54 133 2.7E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS06980 b978ff03052f4b3adf8f104f7303c347 152 Gene3D G3DSA:1.10.530.40 3 152 1.1E-47 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 AFA_RS06980 b978ff03052f4b3adf8f104f7303c347 152 Pfam PF00959 Phage lysozyme 36 141 7.8E-18 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 AFA_RS06980 b978ff03052f4b3adf8f104f7303c347 152 SUPERFAMILY SSF53955 7 151 5.12E-50 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS15240 a1587fe0953bdc0b72ff0ff7fc946d12 335 SUPERFAMILY SSF52821 90 229 5.76E-27 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS15240 a1587fe0953bdc0b72ff0ff7fc946d12 335 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 258 44.414 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 AFA_RS15240 a1587fe0953bdc0b72ff0ff7fc946d12 335 Pfam PF00581 Rhodanese-like domain 116 214 1.2E-5 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS15240 a1587fe0953bdc0b72ff0ff7fc946d12 335 Gene3D G3DSA:3.40.250.10 107 222 3.1E-24 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS15240 a1587fe0953bdc0b72ff0ff7fc946d12 335 SMART SM00450 113 218 8.4E-15 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS10960 e3570a0079afb3da7a04619f55eb1131 266 Pfam PF02602 Uroporphyrinogen-III synthase HemD 17 234 2.1E-30 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10960 e3570a0079afb3da7a04619f55eb1131 266 SUPERFAMILY SSF69618 5 243 4.84E-39 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFA_RS10960 e3570a0079afb3da7a04619f55eb1131 266 Gene3D G3DSA:3.40.50.10090 160 266 3.1E-9 T 28-03-2018 AFA_RS10960 e3570a0079afb3da7a04619f55eb1131 266 Gene3D G3DSA:3.40.50.10090 32 159 1.8E-29 T 28-03-2018 AFA_RS04185 041cce6a27e54c79f41205d129d9b2de 260 SUPERFAMILY SSF55729 27 233 1.33E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS04185 041cce6a27e54c79f41205d129d9b2de 260 Gene3D G3DSA:3.40.630.30 25 173 5.8E-32 T 28-03-2018 AFA_RS04185 041cce6a27e54c79f41205d129d9b2de 260 Pfam PF13444 Acetyltransferase (GNAT) domain 42 142 1.2E-33 T 28-03-2018 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 PRINTS PR00173 Glutamate-aspartate symporter signature 190 209 6.7E-15 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 6.7E-15 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 6.7E-15 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 6.7E-15 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 Pfam PF00375 Sodium:dicarboxylate symporter family 20 399 9.4E-67 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 8 408 35.006 T 28-03-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 SUPERFAMILY SSF118215 20 400 4.18E-92 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS12385 507fc2bc125951c03bc89c16882dfa42 408 Gene3D G3DSA:1.10.3860.10 12 403 2.7E-77 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFA_RS17900 a7476af9c3c433332c2d67e977d4c462 44 Pfam PF13627 Prokaryotic lipoprotein-attachment site 9 31 2.8E-8 T 28-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site AFA_RS08065 4257012d37a0949079331f4cce6b79b3 310 SUPERFAMILY SSF51412 12 306 2.14E-53 T 28-03-2018 AFA_RS08065 4257012d37a0949079331f4cce6b79b3 310 Gene3D G3DSA:3.20.20.70 11 310 3.6E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS08065 4257012d37a0949079331f4cce6b79b3 310 Pfam PF03060 Nitronate monooxygenase 13 79 1.3E-14 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFA_RS08065 4257012d37a0949079331f4cce6b79b3 310 Pfam PF03060 Nitronate monooxygenase 88 255 1.6E-37 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 SMART SM00347 35 135 2.1E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 SUPERFAMILY SSF46785 16 149 1.23E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 Gene3D G3DSA:1.10.10.10 4 151 5.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.4E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.4E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.4E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 4.4E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS09260 42d37c4f79957aa4f614104b822f7ddd 151 Pfam PF01047 MarR family 43 98 1.3E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS17420 ce8396be01e95efbe2c85767ff763285 293 Pfam PF02678 Pirin 20 127 2.7E-35 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFA_RS17420 ce8396be01e95efbe2c85767ff763285 293 Gene3D G3DSA:2.60.120.10 1 257 1.1E-80 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS17420 ce8396be01e95efbe2c85767ff763285 293 Pfam PF05726 Pirin C-terminal cupin domain 182 284 6.4E-27 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFA_RS17420 ce8396be01e95efbe2c85767ff763285 293 SUPERFAMILY SSF51182 1 286 2.76E-85 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS17420 ce8396be01e95efbe2c85767ff763285 293 PIRSF PIRSF006232 2 290 1.3E-89 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 260 1.7E-25 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 261 43.386 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 138 1.1E-7 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 47 6.7E-8 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 3 260 4.0E-100 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Gene3D G3DSA:2.160.10.10 1 191 1.9E-41 T 28-03-2018 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 Gene3D G3DSA:1.20.1180.10 192 262 2.6E-22 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 PIRSF PIRSF000456 1 262 1.9E-101 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AFA_RS10150 3a98c330cd262299fdb81368ad17507b 262 SUPERFAMILY SSF51161 2 261 8.34E-76 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS06600 f19fdfdccfab32bd2ece47d98d6ea037 138 Gene3D G3DSA:3.30.530.20 7 116 2.5E-6 T 28-03-2018 IPR023393 START-like domain AFA_RS06600 f19fdfdccfab32bd2ece47d98d6ea037 138 SUPERFAMILY SSF55961 9 112 7.76E-10 T 28-03-2018 AFA_RS14540 3f12e9a874b6ad89ca3a0fdb18cf1cc1 265 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 253 6.4E-82 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AFA_RS14540 3f12e9a874b6ad89ca3a0fdb18cf1cc1 265 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AFA_RS14540 3f12e9a874b6ad89ca3a0fdb18cf1cc1 265 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 258 20.242 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AFA_RS14540 3f12e9a874b6ad89ca3a0fdb18cf1cc1 265 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 257 9.2E-83 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AFA_RS10325 940be7410b16dadda28744fce9a7b17c 428 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 422 1.6E-132 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS10325 940be7410b16dadda28744fce9a7b17c 428 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 417 1.6E-116 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS10325 940be7410b16dadda28744fce9a7b17c 428 PIRSF PIRSF006066 1 428 1.9E-142 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 Pfam PF00677 Lumazine binding domain 3 86 1.9E-16 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 Pfam PF00677 Lumazine binding domain 101 184 3.0E-20 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 PIRSF PIRSF000498 1 207 8.0E-57 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 Gene3D G3DSA:2.40.30.20 1 89 2.5E-21 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 SUPERFAMILY SSF63380 1 92 4.85E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 Gene3D G3DSA:2.40.30.20 94 191 1.9E-25 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 199 1.4E-57 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS09130 b91364752cd2d29532627d34862a9742 211 SUPERFAMILY SSF63380 93 198 3.66E-27 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS09905 757d98b971f1bf89bebf782432b4dd12 213 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 21 157 1.9E-15 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN AFA_RS09905 757d98b971f1bf89bebf782432b4dd12 213 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 12 154 1.1E-8 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN AFA_RS02270 cad00a90ad29562ac3d8897e12f872d8 420 Gene3D G3DSA:3.40.190.10 141 416 2.0E-55 T 28-03-2018 AFA_RS02270 cad00a90ad29562ac3d8897e12f872d8 420 Pfam PF13416 Bacterial extracellular solute-binding protein 46 355 1.7E-47 T 28-03-2018 AFA_RS02270 cad00a90ad29562ac3d8897e12f872d8 420 SUPERFAMILY SSF53850 25 413 3.72E-81 T 28-03-2018 AFA_RS06470 f324c04c12a90f53aa3b15c10e2ea19d 159 Pfam PF04314 Copper chaperone PCu(A)C 28 129 1.2E-35 T 28-03-2018 IPR007410 Copper chaperone PCuAC AFA_RS06470 f324c04c12a90f53aa3b15c10e2ea19d 159 SUPERFAMILY SSF110087 5 144 6.93E-44 T 28-03-2018 IPR007410 Copper chaperone PCuAC AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 Gene3D G3DSA:2.60.40.420 20 146 5.4E-14 T 28-03-2018 IPR008972 Cupredoxin AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 21 146 2.5E-30 T 28-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 SUPERFAMILY SSF49503 21 146 2.23E-46 T 28-03-2018 IPR008972 Cupredoxin AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 TIGRFAM TIGR02695 azurin: azurin 22 146 7.3E-65 T 28-03-2018 IPR014068 Azurin AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 24 147 3.0E-62 T 28-03-2018 AFA_RS18335 c17a210d394a00fc5362dda20ed64ed7 148 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 124 140 - T 28-03-2018 IPR028871 Blue (type 1) copper protein, binding site AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 1.3E-61 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 415 499 6.2E-17 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 284 1.1E-21 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Gene3D G3DSA:1.10.1040.10 186 289 9.0E-22 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Gene3D G3DSA:1.10.1040.10 412 502 5.8E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 SUPERFAMILY SSF48179 415 499 8.42E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 SUPERFAMILY SSF51735 1 186 2.52E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 SUPERFAMILY SSF48179 186 297 3.32E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS01790 fb593acb504a272ddb289bf8e994c8e9 511 Gene3D G3DSA:3.40.50.720 1 185 1.3E-54 T 28-03-2018 AFA_RS09220 1d7d3365c2084ebb00e2e987a4871708 149 Pfam PF00011 Hsp20/alpha crystallin family 47 145 2.7E-20 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain AFA_RS09220 1d7d3365c2084ebb00e2e987a4871708 149 SUPERFAMILY SSF49764 21 139 3.14E-33 T 28-03-2018 IPR008978 HSP20-like chaperone AFA_RS09220 1d7d3365c2084ebb00e2e987a4871708 149 Gene3D G3DSA:2.60.40.790 8 149 6.1E-31 T 28-03-2018 IPR008978 HSP20-like chaperone AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.8E-35 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 5.9E-84 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFA_RS01355 66280990b6afff879db04751394bde8b 187 Gene3D G3DSA:3.40.50.880 1 187 2.1E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS01355 66280990b6afff879db04751394bde8b 187 Pfam PF00117 Glutamine amidotransferase class-I 4 185 4.3E-57 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.2E-5 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.2E-5 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.1E-13 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 3.1E-13 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 3.1E-13 T 28-03-2018 AFA_RS01355 66280990b6afff879db04751394bde8b 187 SUPERFAMILY SSF52317 2 186 1.58E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS04395 15353237e382f71429cb683dca3b2791 370 Gene3D G3DSA:2.130.10.10 47 365 1.1E-38 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS04395 15353237e382f71429cb683dca3b2791 370 SUPERFAMILY SSF51004 54 346 7.32E-34 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 SUPERFAMILY SSF50685 54 424 6.28E-120 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 Pfam PF03562 MltA specific insert domain 76 324 6.5E-79 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 PIRSF PIRSF019422 2 430 4.0E-126 T 28-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 Gene3D G3DSA:2.40.40.10 58 176 1.0E-13 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 Pfam PF06725 3D domain 347 420 2.6E-26 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 SMART SM00925 168 324 2.1E-79 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 AFA_RS01385 a38e3a0351e1eb9959c8490e32b1295e 431 Gene3D G3DSA:2.40.240.50 177 327 3.5E-59 T 28-03-2018 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 Gene3D G3DSA:1.10.10.10 9 93 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 Gene3D G3DSA:3.40.190.10 94 187 1.3E-16 T 28-03-2018 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 Gene3D G3DSA:3.40.190.10 188 268 3.1E-9 T 28-03-2018 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 SUPERFAMILY SSF53850 98 296 6.04E-32 T 28-03-2018 AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 SUPERFAMILY SSF46785 12 116 2.53E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10450 4062e7dce8d2588956bb0e0b6075cfdd 297 Pfam PF03466 LysR substrate binding domain 97 293 3.0E-29 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 SMART SM00382 369 567 1.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 Gene3D G3DSA:3.40.50.300 342 594 1.8E-58 T 28-03-2018 AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 297 2.3E-35 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 Gene3D G3DSA:1.10.3470.10 6 302 1.5E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 Pfam PF00005 ABC transporter 361 518 9.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 SUPERFAMILY SSF52540 344 588 8.78E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13245 08b4bc784960c801a0db8aab4768944b 610 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 568 589 6.4E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS18480 58274c8c663aba97984ba423e1db4ed4 151 Gene3D G3DSA:1.20.1170.10 22 141 4.0E-5 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 70 127 1.2E-26 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 Pfam PF00361 Proton-conducting membrane transporter 139 433 4.2E-87 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 116 136 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 431 450 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 88 113 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 163 184 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 258 284 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 257 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 326 338 3.3E-64 T 28-03-2018 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 64 88 1.6E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 90 110 1.6E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 482 503 1.6E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 369 391 1.6E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFA_RS13365 b57bbfa9721e3236448070f0b6384a18 667 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 662 3.0E-242 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS01735 ec61376e1fe91d3676e1fe8242398984 267 SUPERFAMILY SSF46689 200 250 8.51E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS01735 ec61376e1fe91d3676e1fe8242398984 267 Gene3D G3DSA:1.10.10.60 120 251 2.1E-9 T 28-03-2018 AFA_RS00110 cbd8c13578a777ce87a81238889d19f4 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 273 2.1E-42 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS00110 cbd8c13578a777ce87a81238889d19f4 285 Gene3D G3DSA:1.10.3470.10 1 278 2.4E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS15025 c7d6680c2288302f20cc30dffac9e9fc 323 SUPERFAMILY SSF53850 111 280 1.03E-6 T 28-03-2018 AFA_RS15025 c7d6680c2288302f20cc30dffac9e9fc 323 Gene3D G3DSA:3.40.190.10 120 230 6.2E-9 T 28-03-2018 AFA_RS15025 c7d6680c2288302f20cc30dffac9e9fc 323 PIRSF PIRSF017082 6 322 5.1E-48 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS15025 c7d6680c2288302f20cc30dffac9e9fc 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 1.5E-53 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS09945 adb29f69e6fafc0a49b566a84910ab78 572 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 2 572 1.3E-139 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like AFA_RS09945 adb29f69e6fafc0a49b566a84910ab78 572 Pfam PF05947 Type VI secretion system, TssF 4 571 3.8E-150 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like AFA_RS09945 adb29f69e6fafc0a49b566a84910ab78 572 PIRSF PIRSF028304 1 572 1.2E-134 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like AFA_RS15730 c9e41ee71240d7c4a7286bffa54374fa 222 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 213 2.8E-47 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS15730 c9e41ee71240d7c4a7286bffa54374fa 222 Pfam PF02581 Thiamine monophosphate synthase 13 201 1.9E-47 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS15730 c9e41ee71240d7c4a7286bffa54374fa 222 Gene3D G3DSA:3.20.20.70 3 217 1.2E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS15730 c9e41ee71240d7c4a7286bffa54374fa 222 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 219 22.563 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS15730 c9e41ee71240d7c4a7286bffa54374fa 222 SUPERFAMILY SSF51391 8 217 6.67E-52 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 172 177 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 Gene3D G3DSA:1.10.150.20 43 90 7.2E-5 T 28-03-2018 AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 SUPERFAMILY SSF47781 15 82 1.73E-7 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 SUPERFAMILY SSF102712 120 196 1.05E-5 T 28-03-2018 AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 223 1.2E-60 T 28-03-2018 IPR001405 RadC protein AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 Gene3D G3DSA:3.40.140.10 100 223 7.8E-44 T 28-03-2018 AFA_RS12780 4fc7e7ff2a10e13b8878f27683d0e54c 223 Pfam PF04002 RadC-like JAB domain 103 221 9.3E-43 T 28-03-2018 IPR025657 RadC-like JAB domain AFA_RS08935 27dd32f2039c205eaf46e1c40ef346c9 510 Pfam PF07364 Metallopeptidase family M81 2 293 1.9E-101 T 28-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal AFA_RS08935 27dd32f2039c205eaf46e1c40ef346c9 510 Pfam PF07171 MlrC C-terminus 304 481 3.0E-52 T 28-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal AFA_RS08935 27dd32f2039c205eaf46e1c40ef346c9 510 PIRSF PIRSF012702 1 498 7.7E-168 T 28-03-2018 IPR009197 Microcystin LR degradation protein MlrC AFA_RS17220 40688444456c43dde1888c623671683f 284 Gene3D G3DSA:1.20.5.100 253 283 4.7E-10 T 28-03-2018 AFA_RS17220 40688444456c43dde1888c623671683f 284 Gene3D G3DSA:1.10.760.10 27 249 1.2E-52 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17220 40688444456c43dde1888c623671683f 284 Pfam PF02167 Cytochrome C1 family 38 79 4.1E-6 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AFA_RS17220 40688444456c43dde1888c623671683f 284 Pfam PF02167 Cytochrome C1 family 106 282 1.5E-12 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AFA_RS17220 40688444456c43dde1888c623671683f 284 SUPERFAMILY SSF46626 225 248 2.33E-46 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17220 40688444456c43dde1888c623671683f 284 SUPERFAMILY SSF46626 20 169 2.33E-46 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS00725 fb714228227385297ab35911ae992937 1238 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 1031 1131 3.0E-13 T 28-03-2018 IPR018712 Domain of unknown function DUF2235 AFA_RS00725 fb714228227385297ab35911ae992937 1238 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 844 916 2.8E-11 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 AFA_RS00725 fb714228227385297ab35911ae992937 1238 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 557 586 1.3E-4 T 28-03-2018 IPR006530 YD repeat AFA_RS07975 52cda80b7cf4ec646aa1ecd4e3853532 325 Pfam PF08908 Domain of unknown function (DUF1852) 1 321 3.7E-185 T 28-03-2018 IPR015004 Protein of unknown function DUF1852 AFA_RS07975 52cda80b7cf4ec646aa1ecd4e3853532 325 PIRSF PIRSF034367 1 325 5.1E-195 T 28-03-2018 IPR015004 Protein of unknown function DUF1852 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 Gene3D G3DSA:3.40.50.300 5 263 1.5E-68 T 28-03-2018 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 Pfam PF00005 ABC transporter 25 167 2.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 SUPERFAMILY SSF50331 244 345 9.78E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 Gene3D G3DSA:2.40.50.140 280 341 0.001 T 28-03-2018 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 Pfam PF08402 TOBE domain 277 343 1.5E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 SUPERFAMILY SSF52540 8 247 3.28E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07260 d6ae80a40ecef9caf0379e0412f6f763 361 SMART SM00382 33 225 5.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02095 74bdfa1ebceb6939f1e52663ee2f588d 170 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 31 157 5.1E-31 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 20 698 1.4E-266 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 144 167 - T 28-03-2018 IPR025505 FHIPEP conserved site AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PIRSF PIRSF005419 9 703 7.5E-243 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 Pfam PF00771 FHIPEP family 28 690 3.4E-266 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 139 155 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 188 205 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 158 176 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 239 253 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS05785 8d759515f0c0ca0c9669a4164bcdbe60 703 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 4.7E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 Gene3D G3DSA:2.40.50.100 164 355 2.3E-6 T 28-03-2018 AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 SUPERFAMILY SSF111369 52 263 1.14E-22 T 28-03-2018 AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 Gene3D G3DSA:2.40.50.100 62 118 6.9E-17 T 28-03-2018 AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 263 4.8E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 354 2.6E-63 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS03155 e2471f101d862c341bb4f759c65020b2 361 Gene3D G3DSA:1.10.287.470 119 161 2.2E-10 T 28-03-2018 AFA_RS05795 50ae39abdf0b79844871c380749e6c66 424 Pfam PF07804 HipA-like C-terminal domain 142 387 7.0E-49 T 28-03-2018 IPR012893 HipA-like, C-terminal AFA_RS05795 50ae39abdf0b79844871c380749e6c66 424 Pfam PF13657 HipA N-terminal domain 2 98 4.8E-19 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 AFA_RS05795 50ae39abdf0b79844871c380749e6c66 424 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 1 98 3.2E-25 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 AFA_RS01205 449a84b70b2338695bb22c9a92d0a6d1 276 Pfam PF00483 Nucleotidyl transferase 11 266 6.5E-26 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFA_RS01205 449a84b70b2338695bb22c9a92d0a6d1 276 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 2.4E-110 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 AFA_RS01205 449a84b70b2338695bb22c9a92d0a6d1 276 Gene3D G3DSA:3.90.550.10 1 276 4.9E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS01205 449a84b70b2338695bb22c9a92d0a6d1 276 SUPERFAMILY SSF53448 2 269 8.97E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS07795 4a8ef510ac638a51e459d1d94df6596c 237 SUPERFAMILY SSF52540 9 230 2.99E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07795 4a8ef510ac638a51e459d1d94df6596c 237 Gene3D G3DSA:3.40.50.300 5 235 3.5E-63 T 28-03-2018 AFA_RS07795 4a8ef510ac638a51e459d1d94df6596c 237 Pfam PF00005 ABC transporter 29 177 7.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS07795 4a8ef510ac638a51e459d1d94df6596c 237 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS07795 4a8ef510ac638a51e459d1d94df6596c 237 SMART SM00382 38 227 2.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 SUPERFAMILY SSF110942 520 632 4.71E-35 T 28-03-2018 AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 SMART SM00387 33 189 4.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 SUPERFAMILY SSF55874 10 221 4.32E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 31 40 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 195 213 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 32 54 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 99 116 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 11 31 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 126 148 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 177 194 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PRINTS PR00775 90kDa heat shock protein signature 81 98 5.9E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 Pfam PF00183 Hsp90 protein 220 631 1.4E-132 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 187 1.7E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 Hamap MF_00505 Chaperone protein HtpG [htpG]. 8 632 33.052 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 Gene3D G3DSA:3.30.565.10 2 232 3.8E-56 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 PIRSF PIRSF002583 1 634 1.7E-221 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AFA_RS02390 001d154ee33b61d95fbb0344e3d3d873 634 SUPERFAMILY SSF54211 239 494 7.59E-99 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS05775 9a9498a21e324dd77e0d798379b849f3 213 SUPERFAMILY SSF75708 15 212 7.32E-61 T 28-03-2018 AFA_RS05775 9a9498a21e324dd77e0d798379b849f3 213 Pfam PF04344 Chemotaxis phosphatase, CheZ 19 213 7.1E-71 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 AFA_RS05775 9a9498a21e324dd77e0d798379b849f3 213 PIRSF PIRSF002884 4 213 6.4E-76 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 AFA_RS05775 9a9498a21e324dd77e0d798379b849f3 213 Gene3D G3DSA:1.10.287.500 38 170 4.6E-19 T 28-03-2018 AFA_RS05775 9a9498a21e324dd77e0d798379b849f3 213 Gene3D G3DSA:1.20.5.590 6 36 1.4E-8 T 28-03-2018 AFA_RS09950 b0030255946cdc7761af001c3c57d200 139 SUPERFAMILY SSF160719 31 129 2.48E-20 T 28-03-2018 AFA_RS09950 b0030255946cdc7761af001c3c57d200 139 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 5 135 1.1E-32 T 28-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein AFA_RS09950 b0030255946cdc7761af001c3c57d200 139 Pfam PF04965 Gene 25-like lysozyme 29 116 1.1E-17 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD AFA_RS09950 b0030255946cdc7761af001c3c57d200 139 Gene3D G3DSA:3.10.450.40 8 134 5.5E-24 T 28-03-2018 AFA_RS00350 c84485f043dd7e4021b68c28f4302bd5 345 SUPERFAMILY SSF53850 53 122 1.05E-5 T 28-03-2018 AFA_RS00350 c84485f043dd7e4021b68c28f4302bd5 345 SUPERFAMILY SSF53850 157 268 1.05E-5 T 28-03-2018 AFA_RS00350 c84485f043dd7e4021b68c28f4302bd5 345 Gene3D G3DSA:3.40.190.10 47 215 1.1E-4 T 28-03-2018 AFA_RS00350 c84485f043dd7e4021b68c28f4302bd5 345 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 305 1.3E-37 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 100 138 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 5 378 51.13 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Gene3D G3DSA:3.40.630.10 4 184 2.1E-35 T 28-03-2018 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Gene3D G3DSA:3.30.70.360 185 294 2.6E-24 T 28-03-2018 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Pfam PF01546 Peptidase family M20/M25/M40 66 374 5.5E-47 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 8 376 2.5E-160 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Gene3D G3DSA:3.40.630.10 303 376 0.035 T 28-03-2018 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 Pfam PF07687 Peptidase dimerisation domain 178 283 5.8E-25 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 SUPERFAMILY SSF55031 182 291 7.92E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 SUPERFAMILY SSF53187 7 181 1.47E-66 T 28-03-2018 AFA_RS07570 df3fc97359f94859b92fcc53440052ad 378 SUPERFAMILY SSF53187 295 376 1.47E-66 T 28-03-2018 AFA_RS05635 04dc00c130f768107e9240542a09d74a 306 SUPERFAMILY SSF103481 51 159 1.15E-13 T 28-03-2018 AFA_RS05635 04dc00c130f768107e9240542a09d74a 306 Pfam PF00892 EamA-like transporter family 169 304 1.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS05635 04dc00c130f768107e9240542a09d74a 306 Pfam PF00892 EamA-like transporter family 23 156 5.5E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS05635 04dc00c130f768107e9240542a09d74a 306 SUPERFAMILY SSF103481 213 305 3.27E-10 T 28-03-2018 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 SUPERFAMILY SSF46626 18 116 3.9E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 Gene3D G3DSA:1.10.760.10 118 217 7.1E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 Gene3D G3DSA:1.10.760.10 3 117 2.1E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 PIRSF PIRSF000005 1 219 3.1E-57 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 Pfam PF00034 Cytochrome c 134 205 3.3E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 Pfam PF00034 Cytochrome c 22 117 1.1E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17925 47ef08e7efe2729b37a7002b5a305931 219 SUPERFAMILY SSF46626 131 217 7.98E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS09275 81e1f150ea6789b9841d2e84c028f2b1 372 Gene3D G3DSA:3.60.21.10 1 244 2.9E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS09275 81e1f150ea6789b9841d2e84c028f2b1 372 PIRSF PIRSF033093 1 370 3.3E-92 T 28-03-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type AFA_RS09275 81e1f150ea6789b9841d2e84c028f2b1 372 SUPERFAMILY SSF56300 2 285 4.07E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS09275 81e1f150ea6789b9841d2e84c028f2b1 372 Pfam PF00149 Calcineurin-like phosphoesterase 2 197 2.1E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS10130 54cd8eab8146fe1896f7654649698f88 444 SUPERFAMILY SSF75304 2 439 1.44E-96 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS10130 54cd8eab8146fe1896f7654649698f88 444 Pfam PF01425 Amidase 10 418 1.3E-80 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS10130 54cd8eab8146fe1896f7654649698f88 444 Gene3D G3DSA:3.90.1300.10 1 444 2.4E-97 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 SUPERFAMILY SSF103501 226 388 1.7E-28 T 28-03-2018 IPR023234 NarG-like domain AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 SUPERFAMILY SSF103501 167 199 1.7E-28 T 28-03-2018 IPR023234 NarG-like domain AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 Gene3D G3DSA:1.20.950.20 166 380 1.4E-30 T 28-03-2018 AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 TIGRFAM TIGR02484 CitB: CitB domain protein 31 387 1.1E-121 T 28-03-2018 IPR012830 Citrate utilization protein B AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 Gene3D G3DSA:3.30.70.20 77 135 0.0082 T 28-03-2018 AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 SUPERFAMILY SSF54862 34 108 4.05E-6 T 28-03-2018 AFA_RS09170 7c79351793cea6d128d54462e5563e2e 396 Gene3D G3DSA:3.30.70.20 28 76 4.4E-4 T 28-03-2018 AFA_RS00910 be96cdf4220bc0c9a3e08a83aa084833 274 Gene3D G3DSA:2.120.10.30 112 267 2.0E-18 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFA_RS00910 be96cdf4220bc0c9a3e08a83aa084833 274 Gene3D G3DSA:2.120.10.30 9 111 4.0E-5 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFA_RS00910 be96cdf4220bc0c9a3e08a83aa084833 274 Pfam PF01436 NHL repeat 163 189 7.7E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 AFA_RS00910 be96cdf4220bc0c9a3e08a83aa084833 274 SUPERFAMILY SSF63829 23 267 4.25E-31 T 28-03-2018 AFA_RS16835 497689e7a99c75332172e83f4808fa68 217 Gene3D G3DSA:1.20.950.20 4 217 2.7E-50 T 28-03-2018 AFA_RS16835 497689e7a99c75332172e83f4808fa68 217 Pfam PF01292 Prokaryotic cytochrome b561 12 188 2.6E-26 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFA_RS16835 497689e7a99c75332172e83f4808fa68 217 SUPERFAMILY SSF81342 7 213 8.52E-53 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFA_RS16835 497689e7a99c75332172e83f4808fa68 217 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 10 209 4.7E-57 T 28-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 AFA_RS07810 f6411202290819c551061736ffbdc4a6 298 SUPERFAMILY SSF53474 7 289 2.91E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07810 f6411202290819c551061736ffbdc4a6 298 Pfam PF12697 Alpha/beta hydrolase family 26 288 4.4E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS07810 f6411202290819c551061736ffbdc4a6 298 Gene3D G3DSA:3.40.50.1820 3 298 2.7E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07810 f6411202290819c551061736ffbdc4a6 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 8.1E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS07810 f6411202290819c551061736ffbdc4a6 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 8.1E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS11480 e5b8d956784e56b305dcb2edf9aafc32 408 Pfam PF04191 Phospholipid methyltransferase 273 342 5.7E-10 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 AFA_RS17450 d892bc6844a28f01ec2e797d8bbe2e33 421 Pfam PF07804 HipA-like C-terminal domain 170 384 1.6E-37 T 28-03-2018 IPR012893 HipA-like, C-terminal AFA_RS17450 d892bc6844a28f01ec2e797d8bbe2e33 421 Pfam PF13657 HipA N-terminal domain 23 121 1.2E-6 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 154 29.853 T 28-03-2018 IPR033747 Class I PurE AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 PIRSF PIRSF001338 1 155 4.9E-61 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 SUPERFAMILY SSF52255 1 153 1.96E-59 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 SMART SM01001 1 150 4.2E-87 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 Pfam PF00731 AIR carboxylase 1 148 4.8E-58 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 Gene3D G3DSA:3.40.50.7700 1 155 4.0E-59 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFA_RS03435 e766367bb39ec823b244e1e4ce6331cc 160 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 150 5.2E-58 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 Pfam PF02384 N-6 DNA Methylase 158 464 3.5E-107 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 282 294 8.5E-21 T 28-03-2018 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 181 197 8.5E-21 T 28-03-2018 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 205 219 8.5E-21 T 28-03-2018 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 318 342 8.5E-21 T 28-03-2018 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 Pfam PF12161 HsdM N-terminal domain 10 145 4.9E-32 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 Gene3D G3DSA:3.40.50.150 179 462 4.8E-69 T 28-03-2018 AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 SUPERFAMILY SSF53335 79 486 2.3E-146 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 SUPERFAMILY SSF53335 538 574 2.3E-146 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 SUPERFAMILY SSF53335 8 47 2.3E-146 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS02155 ba996785e9efbd2ee3aaa6e23713daca 574 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 477 1.2E-79 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 AFA_RS04770 9da202f9ea99d2d3852f8da0c0c5675f 366 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 1 359 1.2E-115 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 AFA_RS04770 9da202f9ea99d2d3852f8da0c0c5675f 366 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 1 359 4.5E-114 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 AFA_RS04770 9da202f9ea99d2d3852f8da0c0c5675f 366 PIRSF PIRSF015557 1 364 9.6E-112 T 28-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 SMART SM00448 1 112 2.4E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 216 4.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 SUPERFAMILY SSF52172 1 178 1.42E-41 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 Gene3D G3DSA:1.10.10.10 116 221 9.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 SMART SM00862 145 216 1.3E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 Gene3D G3DSA:3.40.50.2300 1 115 1.0E-35 T 28-03-2018 AFA_RS04235 366e9f9c3d8b964130b2a27a3bb7c74c 221 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 Gene3D G3DSA:1.20.1560.10 1 324 2.2E-27 T 28-03-2018 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 SUPERFAMILY SSF52540 332 552 8.53E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 Pfam PF00005 ABC transporter 354 503 8.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 12 532 1.6E-114 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 SUPERFAMILY SSF90123 10 322 3.14E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 SMART SM00382 363 549 8.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 Gene3D G3DSA:3.40.50.300 325 562 6.2E-56 T 28-03-2018 AFA_RS16295 55bd047157c2ca0c0d3fc1ffcaa8fdfd 564 Pfam PF00664 ABC transporter transmembrane region 77 289 5.3E-11 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 SMART SM01329 6 348 2.8E-172 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 351 1.2E-165 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 Gene3D G3DSA:3.40.718.10 209 353 3.0E-56 T 28-03-2018 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 Gene3D G3DSA:3.40.718.10 1 208 2.9E-59 T 28-03-2018 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 SUPERFAMILY SSF53659 3 352 5.95E-116 T 28-03-2018 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFA_RS12685 e91daa570594b96c4e604677058d6379 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 348 5.3E-86 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFA_RS01490 02f6c2f4027b97f30fb7a1e9a3fac204 181 SUPERFAMILY SSF161098 2 167 2.88E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01490 02f6c2f4027b97f30fb7a1e9a3fac204 181 Gene3D G3DSA:1.10.3720.10 1 181 9.8E-15 T 28-03-2018 AFA_RS01490 02f6c2f4027b97f30fb7a1e9a3fac204 181 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 7 178 6.9E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16470 1dda95fceb7f9418a5a8b316d6cdeb95 163 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 155 22.515 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS16470 1dda95fceb7f9418a5a8b316d6cdeb95 163 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 2.8E-36 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS16470 1dda95fceb7f9418a5a8b316d6cdeb95 163 SUPERFAMILY SSF52121 12 155 6.93E-45 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS16470 1dda95fceb7f9418a5a8b316d6cdeb95 163 Gene3D G3DSA:3.40.50.960 10 162 2.6E-46 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS18535 260b97ca1bae4ee9e3f0aa227176025d 319 Gene3D G3DSA:1.10.3470.10 8 298 1.6E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS18535 260b97ca1bae4ee9e3f0aa227176025d 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 293 2.3E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS01885 6bbc8b0f9ef7f241ca7840018a61b59b 270 Gene3D G3DSA:1.10.10.10 143 246 1.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01885 6bbc8b0f9ef7f241ca7840018a61b59b 270 SMART SM00862 169 242 1.5E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS01885 6bbc8b0f9ef7f241ca7840018a61b59b 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 242 1.4E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS01885 6bbc8b0f9ef7f241ca7840018a61b59b 270 SUPERFAMILY SSF46894 164 243 1.11E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS08645 ba1554e76b67d73b4a254dabaa40158c 79 Pfam PF03891 Domain of unknown function (DUF333) 27 73 6.2E-24 T 28-03-2018 IPR005590 Protein of unknown function DUF333 AFA_RS04935 5c0c4d5b71d319161723f084c2de11e5 493 SUPERFAMILY SSF52091 392 477 2.16E-10 T 28-03-2018 IPR002645 STAS domain AFA_RS04935 5c0c4d5b71d319161723f084c2de11e5 493 Pfam PF00916 Sulfate permease family 144 354 1.9E-31 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFA_RS04935 5c0c4d5b71d319161723f084c2de11e5 493 Gene3D G3DSA:3.30.750.24 387 480 2.3E-12 T 28-03-2018 IPR002645 STAS domain AFA_RS10840 56bd8d73c4e629428426efbfe5561d9c 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 6 474 40.47 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 AFA_RS10840 56bd8d73c4e629428426efbfe5561d9c 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 11 456 5.2E-136 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 1.6E-5 T 28-03-2018 AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 SUPERFAMILY SSF51735 6 247 4.2E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 Gene3D G3DSA:3.40.50.720 5 247 1.4E-72 T 28-03-2018 AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 Pfam PF00106 short chain dehydrogenase 7 198 6.4E-59 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.9E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.9E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.9E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS14010 e42b5bbe57662cc28c494c859fd824f1 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 6 247 5.9E-108 T 28-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 AFA_RS16405 bd7a36a2cb4f7e5559d6eac9403c7c93 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 205 3.2E-10 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16405 bd7a36a2cb4f7e5559d6eac9403c7c93 241 Gene3D G3DSA:3.40.50.1000 8 234 7.4E-21 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16405 bd7a36a2cb4f7e5559d6eac9403c7c93 241 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 23 204 2.3E-45 T 28-03-2018 IPR010237 Pyrimidine 5-nucleotidase AFA_RS16405 bd7a36a2cb4f7e5559d6eac9403c7c93 241 SUPERFAMILY SSF56784 23 234 1.59E-28 T 28-03-2018 IPR023214 HAD-like domain AFA_RS16405 bd7a36a2cb4f7e5559d6eac9403c7c93 241 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 161 206 1.9E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.9E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.975 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.0E-45 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 SUPERFAMILY SSF55653 60 148 2.35E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 Gene3D G3DSA:3.40.5.10 1 49 7.4E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 Gene3D G3DSA:3.10.430.100 63 148 1.3E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 SUPERFAMILY SSF55658 1 56 9.24E-18 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AFA_RS05210 7de9b1e84a7ffffadd4281b798b576ba 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 3.5E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal AFA_RS18530 78ff7b19032c71e548a49fd9cc7a5bf5 291 Gene3D G3DSA:1.10.3470.10 1 290 3.1E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS18530 78ff7b19032c71e548a49fd9cc7a5bf5 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 4.4E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS08970 9e6d68eac312bd5b31b006f982acaedf 737 Pfam PF00593 TonB dependent receptor 282 735 7.2E-45 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS08970 9e6d68eac312bd5b31b006f982acaedf 737 SUPERFAMILY SSF56935 76 736 2.78E-98 T 28-03-2018 AFA_RS08970 9e6d68eac312bd5b31b006f982acaedf 737 Gene3D G3DSA:2.40.170.20 223 736 4.3E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS08970 9e6d68eac312bd5b31b006f982acaedf 737 Gene3D G3DSA:2.170.130.10 70 218 3.4E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS08970 9e6d68eac312bd5b31b006f982acaedf 737 Pfam PF07715 TonB-dependent Receptor Plug Domain 105 213 3.7E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS00245 4291ec784e07fa168eab805fd6edd276 152 SUPERFAMILY SSF46785 6 146 3.58E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00245 4291ec784e07fa168eab805fd6edd276 152 Gene3D G3DSA:1.10.10.10 2 150 6.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00245 4291ec784e07fa168eab805fd6edd276 152 SMART SM00347 32 132 3.8E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00245 4291ec784e07fa168eab805fd6edd276 152 Pfam PF01047 MarR family 39 96 8.0E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00245 4291ec784e07fa168eab805fd6edd276 152 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 SMART SM00062 34 263 8.1E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 1.3E-28 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 Gene3D G3DSA:3.40.190.10 137 226 1.9E-17 T 28-03-2018 AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 SUPERFAMILY SSF53850 25 254 1.12E-45 T 28-03-2018 AFA_RS15835 ee1079c9540bd6734f1082d37ecc5eed 338 Gene3D G3DSA:3.40.190.10 24 136 1.7E-15 T 28-03-2018 AFA_RS09235 c435e99764251b52900ee1c96d1d15b6 374 SUPERFAMILY SSF103473 3 368 1.57E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS09235 c435e99764251b52900ee1c96d1d15b6 374 Gene3D G3DSA:1.20.1250.20 190 371 1.5E-8 T 28-03-2018 AFA_RS09235 c435e99764251b52900ee1c96d1d15b6 374 Pfam PF07690 Major Facilitator Superfamily 19 342 7.6E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS09235 c435e99764251b52900ee1c96d1d15b6 374 Gene3D G3DSA:1.20.1250.20 1 189 2.0E-28 T 28-03-2018 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 ProSitePatterns PS00171 Triosephosphate isomerase active site. 169 179 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 SUPERFAMILY SSF51351 7 245 9.42E-88 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 7 246 38.575 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 Pfam PF00121 Triosephosphate isomerase 10 244 1.3E-87 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 Gene3D G3DSA:3.20.20.70 1 246 3.5E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS13440 4b31a7e6ae56f0eb27e2c0ef0d36e626 246 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 10 237 6.6E-64 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 SMART SM00881 13 109 0.0082 T 28-03-2018 IPR003781 CoA-binding GO:0048037 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 9.4E-61 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 SUPERFAMILY SSF48179 183 330 6.97E-65 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 PIRSF PIRSF000116 201 332 7.5E-12 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 PIRSF PIRSF000116 2 205 1.3E-46 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 Gene3D G3DSA:3.40.50.720 33 179 8.5E-53 T 28-03-2018 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.8E-70 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 Gene3D G3DSA:1.10.1040.10 180 337 1.0E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 8.5E-129 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.222 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFA_RS00085 ae536021d88e923b3b34d62306f21b92 338 SUPERFAMILY SSF51735 1 181 2.09E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS10295 b9e094c9cd8f687b2fcf29b39cd61eec 203 Pfam PF02630 SCO1/SenC 46 180 1.9E-33 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS10295 b9e094c9cd8f687b2fcf29b39cd61eec 203 SUPERFAMILY SSF52833 47 202 3.14E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10295 b9e094c9cd8f687b2fcf29b39cd61eec 203 Gene3D G3DSA:3.40.30.10 38 202 1.2E-28 T 28-03-2018 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 Gene3D G3DSA:1.10.1740.10 8 77 1.5E-8 T 28-03-2018 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 SUPERFAMILY SSF88659 90 165 1.33E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 Pfam PF04542 Sigma-70 region 2 14 75 6.0E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 SUPERFAMILY SSF88946 12 93 7.06E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 3.6E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 Pfam PF08281 Sigma-70, region 4 106 158 3.9E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS16720 297ed4ad115ad2bb7415bb971ee4415b 168 Gene3D G3DSA:1.10.10.10 78 165 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14360 b9d998e529610dc9e9cc7f4507ce8d21 269 Pfam PF00994 Probable molybdopterin binding domain 11 176 6.4E-24 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS14360 b9d998e529610dc9e9cc7f4507ce8d21 269 SMART SM00852 10 183 1.0E-32 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS14360 b9d998e529610dc9e9cc7f4507ce8d21 269 SUPERFAMILY SSF53218 8 217 7.85E-37 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS14360 b9d998e529610dc9e9cc7f4507ce8d21 269 Gene3D G3DSA:3.40.980.10 5 182 6.6E-41 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 SUPERFAMILY SSF46785 7 66 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 Gene3D G3DSA:3.30.70.920 61 154 1.7E-23 T 28-03-2018 AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 SUPERFAMILY SSF54909 69 156 1.61E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 Pfam PF01037 Lrp/AsnC ligand binding domain 74 148 1.6E-18 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 54 7.3E-16 T 28-03-2018 AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 SMART SM00344 8 117 1.3E-40 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 Gene3D G3DSA:1.10.10.10 2 59 5.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 3.6E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 3.6E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS13865 892c4ad03c86c89e6a7cbdff1444d262 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 3.6E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS12020 313465fafbcba564f469f8ff52113496 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.1E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.1E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.1E-14 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 Gene3D G3DSA:3.30.70.20 45 106 8.2E-8 T 28-03-2018 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 Gene3D G3DSA:3.30.70.20 2 44 3.8E-13 T 28-03-2018 AFA_RS12020 313465fafbcba564f469f8ff52113496 110 Pfam PF00037 4Fe-4S binding domain 34 55 6.1E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS12020 313465fafbcba564f469f8ff52113496 110 Pfam PF11953 Domain of unknown function (DUF3470) 67 108 5.2E-12 T 28-03-2018 IPR022569 Ferredoxin, C-terminal AFA_RS12020 313465fafbcba564f469f8ff52113496 110 SUPERFAMILY SSF54862 1 95 3.87E-22 T 28-03-2018 AFA_RS15325 a7caa4a7da0abdc28bdeafa4952ae6a0 748 Gene3D G3DSA:3.40.720.10 83 371 1.5E-21 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS15325 a7caa4a7da0abdc28bdeafa4952ae6a0 748 Gene3D G3DSA:2.60.120.200 469 738 7.5E-14 T 28-03-2018 AFA_RS15325 a7caa4a7da0abdc28bdeafa4952ae6a0 748 SUPERFAMILY SSF49899 696 743 1.45E-9 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain AFA_RS15325 a7caa4a7da0abdc28bdeafa4952ae6a0 748 SUPERFAMILY SSF49899 548 665 1.45E-9 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain AFA_RS15325 a7caa4a7da0abdc28bdeafa4952ae6a0 748 SUPERFAMILY SSF53649 84 350 2.04E-19 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS00165 2c9cd3857be7ffad19a26a217bba7980 308 SUPERFAMILY SSF103481 51 147 3.53E-11 T 28-03-2018 AFA_RS00165 2c9cd3857be7ffad19a26a217bba7980 308 SUPERFAMILY SSF103481 195 298 1.15E-9 T 28-03-2018 AFA_RS00165 2c9cd3857be7ffad19a26a217bba7980 308 Pfam PF00892 EamA-like transporter family 16 144 2.8E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS00165 2c9cd3857be7ffad19a26a217bba7980 308 Pfam PF00892 EamA-like transporter family 160 295 4.7E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 Gene3D G3DSA:2.30.40.10 417 481 0.001 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 Gene3D G3DSA:2.30.40.10 72 144 4.0E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 SUPERFAMILY SSF51338 443 484 5.83E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 SUPERFAMILY SSF51338 74 129 5.83E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 Gene3D G3DSA:3.20.20.140 145 416 1.9E-37 T 28-03-2018 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 Pfam PF01979 Amidohydrolase family 125 482 1.5E-25 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS06435 754e9488bbb5b1cf606dff12bbc7eee1 490 SUPERFAMILY SSF51556 129 433 4.35E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS15265 b272271092e20b1de11ab49b5887a01c 186 Gene3D G3DSA:2.60.120.10 42 185 1.3E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS15265 b272271092e20b1de11ab49b5887a01c 186 Gene3D G3DSA:1.20.5.440 2 41 2.7E-9 T 28-03-2018 AFA_RS15265 b272271092e20b1de11ab49b5887a01c 186 SUPERFAMILY SSF51182 1 183 1.36E-52 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS15265 b272271092e20b1de11ab49b5887a01c 186 Pfam PF05995 Cysteine dioxygenase type I 70 162 5.7E-7 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 AFA_RS04995 8d022599b5c746850db3dbe26ab716f5 180 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 6 65 3.8E-30 T 28-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal AFA_RS04995 8d022599b5c746850db3dbe26ab716f5 180 Pfam PF05233 PHB accumulation regulatory domain 120 159 2.1E-14 T 28-03-2018 IPR007897 PHB accumulation regulatory AFA_RS04995 8d022599b5c746850db3dbe26ab716f5 180 Pfam PF05233 PHB accumulation regulatory domain 70 108 2.1E-18 T 28-03-2018 IPR007897 PHB accumulation regulatory AFA_RS04995 8d022599b5c746850db3dbe26ab716f5 180 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 5 111 4.3E-46 T 28-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 PIRSF PIRSF010376 2 289 7.3E-83 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 276 30.995 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 Pfam PF08544 GHMP kinases C terminal 220 266 1.9E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 Pfam PF00288 GHMP kinases N terminal domain 87 144 3.3E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 Gene3D G3DSA:3.30.70.890 162 312 3.2E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 SUPERFAMILY SSF54211 5 157 1.21E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 Gene3D G3DSA:3.30.230.10 4 160 2.5E-48 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 SUPERFAMILY SSF55060 161 266 6.23E-18 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain AFA_RS02800 0fdad49eec2810914709d59d6d730bbd 312 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 265 8.2E-68 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFA_RS16320 277459cc2464358167aa181e576c3617 188 Gene3D G3DSA:1.10.10.10 2 172 1.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16320 277459cc2464358167aa181e576c3617 188 Pfam PF12802 MarR family 26 78 1.7E-7 T 28-03-2018 AFA_RS16320 277459cc2464358167aa181e576c3617 188 PIRSF PIRSF006707 1 174 1.6E-53 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type AFA_RS16320 277459cc2464358167aa181e576c3617 188 SUPERFAMILY SSF46785 7 148 1.74E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 Pfam PF00850 Histone deacetylase domain 5 288 5.5E-80 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 Gene3D G3DSA:3.40.800.20 1 292 5.4E-105 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 PRINTS PR01270 Histone deacetylase superfamily signature 219 229 3.1E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 PRINTS PR01270 Histone deacetylase superfamily signature 107 130 3.1E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 PRINTS PR01270 Histone deacetylase superfamily signature 141 156 3.1E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFA_RS11915 1b2df768fd9a1e8d0c97a9e22c957e38 292 SUPERFAMILY SSF52768 2 291 1.58E-99 T 28-03-2018 AFA_RS06270 4a4c1e9469033d5d73bfcfb9e82f98a7 383 SUPERFAMILY SSF52540 14 356 4.34E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS06270 4a4c1e9469033d5d73bfcfb9e82f98a7 383 Pfam PF13538 UvrD-like helicase C-terminal domain 302 350 6.1E-9 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain AFA_RS06270 4a4c1e9469033d5d73bfcfb9e82f98a7 383 Pfam PF13245 AAA domain 24 171 5.7E-6 T 28-03-2018 AFA_RS06270 4a4c1e9469033d5d73bfcfb9e82f98a7 383 Gene3D G3DSA:3.40.50.300 190 372 8.9E-16 T 28-03-2018 AFA_RS06270 4a4c1e9469033d5d73bfcfb9e82f98a7 383 Gene3D G3DSA:3.40.50.300 7 175 3.2E-15 T 28-03-2018 AFA_RS17780 250b225ea0cb9e5fa422da7ef62d315a 92 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 84 2.0E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17780 250b225ea0cb9e5fa422da7ef62d315a 92 SUPERFAMILY SSF54292 2 92 2.23E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17780 250b225ea0cb9e5fa422da7ef62d315a 92 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS17780 250b225ea0cb9e5fa422da7ef62d315a 92 Gene3D G3DSA:3.10.20.30 1 92 4.0E-22 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS12500 c366d204290e9ecc9f75d97bb44e9145 232 Gene3D G3DSA:1.20.950.20 3 202 6.5E-27 T 28-03-2018 AFA_RS12500 c366d204290e9ecc9f75d97bb44e9145 232 SUPERFAMILY SSF81342 6 186 1.41E-32 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFA_RS12500 c366d204290e9ecc9f75d97bb44e9145 232 Pfam PF01292 Prokaryotic cytochrome b561 11 181 3.4E-17 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 Gene3D G3DSA:3.90.220.20 5 201 1.5E-24 T 28-03-2018 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 Gene3D G3DSA:3.90.220.20 202 408 7.2E-30 T 28-03-2018 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 SUPERFAMILY SSF116734 7 226 2.78E-38 T 28-03-2018 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 Gene3D G3DSA:1.10.287.1120 409 448 2.7E-7 T 28-03-2018 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 SUPERFAMILY SSF116734 226 448 9.32E-39 T 28-03-2018 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 Pfam PF01420 Type I restriction modification DNA specificity domain 242 416 2.2E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFA_RS12290 156fc6b5fe03adf0c7657c6060f72fe1 450 Pfam PF01420 Type I restriction modification DNA specificity domain 22 197 2.1E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFA_RS10155 4e74d44b9517e05820c31b5b5a5ae86e 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 146 1.1E-57 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS10155 4e74d44b9517e05820c31b5b5a5ae86e 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 148 34.617 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS10155 4e74d44b9517e05820c31b5b5a5ae86e 151 Gene3D G3DSA:3.10.129.10 1 151 9.0E-58 T 28-03-2018 AFA_RS10155 4e74d44b9517e05820c31b5b5a5ae86e 151 Pfam PF07977 FabA-like domain 12 141 4.4E-40 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS10155 4e74d44b9517e05820c31b5b5a5ae86e 151 SUPERFAMILY SSF54637 5 147 2.64E-48 T 28-03-2018 IPR029069 HotDog domain AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 6.4E-159 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 39.949 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 244 421 1.1E-32 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 SUPERFAMILY SSF46589 1 112 2.82E-29 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 7.0E-32 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 7.0E-32 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 7.0E-32 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 7.0E-32 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 7.0E-32 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 Gene3D G3DSA:3.30.930.10 105 448 2.1E-96 T 28-03-2018 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 SUPERFAMILY SSF55681 134 439 1.18E-95 T 28-03-2018 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 Gene3D G3DSA:1.10.287.40 1 104 1.0E-21 T 28-03-2018 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.4E-26 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AFA_RS13530 d8314dee30fbe2bfd97db809575a9778 448 PIRSF PIRSF001529 1 447 2.2E-169 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 Gene3D G3DSA:2.40.50.140 1 107 1.1E-42 T 28-03-2018 AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 107 1.1E-47 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 PIRSF PIRSF002070 1 107 7.3E-36 T 28-03-2018 AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 SUPERFAMILY SSF50249 3 107 2.09E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 Pfam PF00436 Single-strand binding protein family 4 107 3.1E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFA_RS06710 4a492f359af24418c11257da3c64a20b 107 Hamap MF_00984 Single-stranded DNA-binding protein. 4 107 34.335 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 44 227 9.7E-69 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 61 81 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 120 140 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 44 61 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 203 227 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 99 119 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 155 181 2.3E-47 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFA_RS02895 2df80cea2851c497f211d80dde857bd0 243 Pfam PF01578 Cytochrome C assembly protein 25 183 2.8E-29 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 Gene3D G3DSA:1.10.287.950 223 329 1.6E-7 T 28-03-2018 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 Gene3D G3DSA:1.10.287.950 330 529 5.0E-48 T 28-03-2018 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 SMART SM01049 47 141 1.2E-33 T 28-03-2018 IPR033480 Single Cache domain 2 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 Pfam PF17200 Single Cache domain 2 51 197 2.2E-35 T 28-03-2018 IPR033480 Single Cache domain 2 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 SUPERFAMILY SSF58104 270 528 6.28E-64 T 28-03-2018 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 Gene3D G3DSA:3.30.450.20 42 200 9.4E-43 T 28-03-2018 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 301 330 1.1E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 407 436 1.1E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 378 405 1.1E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 455 484 1.1E-43 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 SMART SM00283 280 527 2.9E-74 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS01405 b59441cc93ba3e1854e674f752c2c6de 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 494 9.0E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS12865 58e478b001b4baa351a6cbe1ef06eb54 172 Pfam PF06271 RDD family 8 156 3.1E-20 T 28-03-2018 IPR010432 RDD AFA_RS12910 e21ae1502db9a142269cf8757a2bd928 284 Pfam PF00793 DAHP synthetase I family 9 275 7.1E-67 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS12910 e21ae1502db9a142269cf8757a2bd928 284 SUPERFAMILY SSF51569 2 276 7.24E-100 T 28-03-2018 AFA_RS12910 e21ae1502db9a142269cf8757a2bd928 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 14 275 2.6E-120 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS12910 e21ae1502db9a142269cf8757a2bd928 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 9 277 52.37 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS12910 e21ae1502db9a142269cf8757a2bd928 284 Gene3D G3DSA:3.20.20.70 12 279 7.2E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS17860 98ca599aa30e0b7ed5a22bcbde8c7dfe 411 Gene3D G3DSA:1.20.1250.20 222 410 9.1E-20 T 28-03-2018 AFA_RS17860 98ca599aa30e0b7ed5a22bcbde8c7dfe 411 Gene3D G3DSA:1.20.1250.20 17 217 2.1E-27 T 28-03-2018 AFA_RS17860 98ca599aa30e0b7ed5a22bcbde8c7dfe 411 SUPERFAMILY SSF103473 24 409 1.44E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17860 98ca599aa30e0b7ed5a22bcbde8c7dfe 411 Pfam PF07690 Major Facilitator Superfamily 32 358 6.8E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS17090 4eff2ca2ff4a1f87754b88fc9c4dc533 274 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS17090 4eff2ca2ff4a1f87754b88fc9c4dc533 274 SMART SM00382 34 223 5.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS17090 4eff2ca2ff4a1f87754b88fc9c4dc533 274 Gene3D G3DSA:3.40.50.300 6 251 7.9E-61 T 28-03-2018 AFA_RS17090 4eff2ca2ff4a1f87754b88fc9c4dc533 274 Pfam PF00005 ABC transporter 25 174 3.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS17090 4eff2ca2ff4a1f87754b88fc9c4dc533 274 SUPERFAMILY SSF52540 9 240 1.69E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13400 3fdfcb1038167e8680525e7b746d3b79 164 SUPERFAMILY SSF52833 3 160 4.36E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS13400 3fdfcb1038167e8680525e7b746d3b79 164 Gene3D G3DSA:3.40.30.10 75 164 9.6E-11 T 28-03-2018 AFA_RS13400 3fdfcb1038167e8680525e7b746d3b79 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 158 5.9E-57 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13400 3fdfcb1038167e8680525e7b746d3b79 164 PIRSF PIRSF000216 2 164 1.2E-52 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13400 3fdfcb1038167e8680525e7b746d3b79 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 158 4.9E-46 T 28-03-2018 AFA_RS14740 b049e9c1f18e30643b5d2a324c5b81b7 303 Gene3D G3DSA:3.40.50.620 5 268 7.4E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS14740 b049e9c1f18e30643b5d2a324c5b81b7 303 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 256 1.2E-46 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 AFA_RS14740 b049e9c1f18e30643b5d2a324c5b81b7 303 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 303 3.9E-125 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFA_RS14740 b049e9c1f18e30643b5d2a324c5b81b7 303 SUPERFAMILY SSF52402 8 210 1.48E-63 T 28-03-2018 AFA_RS14740 b049e9c1f18e30643b5d2a324c5b81b7 303 PIRSF PIRSF002936 4 303 9.2E-137 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFA_RS15760 9833d1452e6fc635d6eb9e8f8145990d 67 Gene3D G3DSA:1.10.1470.10 1 67 1.8E-19 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS15760 9833d1452e6fc635d6eb9e8f8145990d 67 SUPERFAMILY SSF69047 1 66 1.16E-24 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS15760 9833d1452e6fc635d6eb9e8f8145990d 67 PIRSF PIRSF039008 1 66 1.4E-27 T 28-03-2018 IPR026042 Stress response protein YjbJ AFA_RS15760 9833d1452e6fc635d6eb9e8f8145990d 67 Pfam PF05532 CsbD-like 4 56 2.1E-17 T 28-03-2018 IPR008462 CsbD-like domain AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 Pfam PF00700 Bacterial flagellin C-terminal helical region 357 441 5.0E-30 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 PRINTS PR00207 Flagellin signature 36 53 1.6E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 PRINTS PR00207 Flagellin signature 110 133 1.6E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 PRINTS PR00207 Flagellin signature 75 94 1.6E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 139 3.5E-43 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 SUPERFAMILY SSF64518 1 442 1.7E-101 T 28-03-2018 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 Gene3D G3DSA:1.20.1330.10 39 414 1.8E-72 T 28-03-2018 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 Pfam PF08884 Flagellin D3 domain 288 349 2.4E-10 T 28-03-2018 IPR014981 Flagellin D3 AFA_RS06010 8354783a3405136248ff75d1bca6468a 442 Pfam PF08884 Flagellin D3 domain 192 272 5.4E-8 T 28-03-2018 IPR014981 Flagellin D3 AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 ProSitePatterns PS00892 HIT domain signature. 91 109 - T 28-03-2018 IPR019808 Histidine triad, conserved site AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 Gene3D G3DSA:3.30.428.10 1 117 9.1E-34 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 PRINTS PR00332 Histidine triad family signature 98 108 4.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 PRINTS PR00332 Histidine triad family signature 6 22 4.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 PRINTS PR00332 Histidine triad family signature 27 45 4.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 Pfam PF01230 HIT domain 13 111 7.9E-27 T 28-03-2018 IPR001310 Histidine triad (HIT) protein AFA_RS17175 2c13c1ffbef570f6c578cd26d684a950 122 SUPERFAMILY SSF54197 1 110 1.33E-37 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 SMART SM00116 189 237 4.5E-7 T 28-03-2018 IPR000644 CBS domain AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Gene3D G3DSA:3.10.580.10 101 249 5.6E-15 T 28-03-2018 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Pfam PF01769 Divalent cation transporter 304 434 2.1E-29 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 SUPERFAMILY SSF158791 15 113 2.22E-13 T 28-03-2018 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Pfam PF00571 CBS domain 199 237 1.9E-6 T 28-03-2018 IPR000644 CBS domain AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 SUPERFAMILY SSF54631 116 256 1.31E-24 T 28-03-2018 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Pfam PF03448 MgtE intracellular N domain 16 115 4.3E-12 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 TIGRFAM TIGR00400 mgtE: magnesium transporter 17 442 2.5E-105 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Gene3D G3DSA:1.25.60.10 9 100 5.9E-9 T 28-03-2018 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 SUPERFAMILY SSF161093 263 441 2.62E-47 T 28-03-2018 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 Gene3D G3DSA:1.10.357.20 260 444 3.5E-42 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFA_RS06620 b571b2dbcb49810c275514833638a4fe 446 SMART SM00924 14 117 6.0E-13 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFA_RS01025 3a9317f6982d02f97981b73828bb9f1c 332 Pfam PF16868 NMT1-like family 41 330 1.4E-93 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFA_RS01025 3a9317f6982d02f97981b73828bb9f1c 332 Gene3D G3DSA:3.40.190.10 156 332 2.6E-40 T 28-03-2018 AFA_RS01025 3a9317f6982d02f97981b73828bb9f1c 332 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 14 330 7.6E-105 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFA_RS01025 3a9317f6982d02f97981b73828bb9f1c 332 Gene3D G3DSA:3.40.190.10 33 155 2.0E-22 T 28-03-2018 AFA_RS01025 3a9317f6982d02f97981b73828bb9f1c 332 SUPERFAMILY SSF53850 36 331 4.49E-82 T 28-03-2018 AFA_RS09315 d1b9687c01974b0c7cc1be313f91a0d0 398 SUPERFAMILY SSF103473 10 382 4.19E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS09315 d1b9687c01974b0c7cc1be313f91a0d0 398 Gene3D G3DSA:1.20.1250.20 11 199 6.8E-22 T 28-03-2018 AFA_RS09315 d1b9687c01974b0c7cc1be313f91a0d0 398 Pfam PF07690 Major Facilitator Superfamily 17 289 2.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS09315 d1b9687c01974b0c7cc1be313f91a0d0 398 Gene3D G3DSA:1.20.1250.20 201 397 1.2E-9 T 28-03-2018 AFA_RS09040 65976bd2766e60326732fec415b2411a 153 Gene3D G3DSA:1.10.1510.10 3 92 5.1E-29 T 28-03-2018 AFA_RS09040 65976bd2766e60326732fec415b2411a 153 SUPERFAMILY SSF89095 4 152 2.93E-39 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 AFA_RS09040 65976bd2766e60326732fec415b2411a 153 Pfam PF09424 Yqey-like protein 6 151 4.0E-51 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial AFA_RS09040 65976bd2766e60326732fec415b2411a 153 Gene3D G3DSA:1.10.10.410 93 152 3.9E-17 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 Gene3D G3DSA:3.40.980.10 8 173 6.9E-28 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 SMART SM00852 16 160 5.8E-16 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 SUPERFAMILY SSF53218 11 169 2.36E-37 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 PIRSF PIRSF006443 1 168 7.4E-54 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 Pfam PF00994 Probable molybdopterin binding domain 16 157 1.2E-23 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 12 168 1.1E-67 T 28-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 AFA_RS03075 b1ef534c7e6bc04735aff0938811c956 176 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 154 9.3E-28 T 28-03-2018 IPR001453 MoaB/Mog domain AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 Gene3D G3DSA:1.20.1250.20 270 476 1.4E-20 T 28-03-2018 AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 Gene3D G3DSA:1.20.1250.20 1 211 1.1E-32 T 28-03-2018 AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 445 3.1E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 Pfam PF07690 Major Facilitator Superfamily 30 420 3.9E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 SUPERFAMILY SSF103473 13 211 5.1E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS16110 a1a5c6a76c3bf985e1e188c3a2903633 477 SUPERFAMILY SSF103473 259 466 5.1E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS03460 faa21f57d2ee5b43d1522b2d4b346524 148 SUPERFAMILY SSF54637 2 141 1.49E-30 T 28-03-2018 IPR029069 HotDog domain AFA_RS03460 faa21f57d2ee5b43d1522b2d4b346524 148 Pfam PF01575 MaoC like domain 8 109 1.1E-11 T 28-03-2018 IPR002539 MaoC-like domain AFA_RS03460 faa21f57d2ee5b43d1522b2d4b346524 148 Gene3D G3DSA:3.10.129.10 1 148 2.9E-27 T 28-03-2018 AFA_RS07855 d443a798eb4abfb3299d360c08ef2acb 275 SUPERFAMILY SSF52540 4 227 1.67E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07855 d443a798eb4abfb3299d360c08ef2acb 275 Gene3D G3DSA:3.40.50.300 22 275 6.3E-15 T 28-03-2018 AFA_RS07855 d443a798eb4abfb3299d360c08ef2acb 275 Pfam PF13481 AAA domain 9 180 4.7E-33 T 28-03-2018 AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 256 7.6E-63 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 SMART SM00062 29 258 6.0E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 Gene3D G3DSA:3.40.190.10 143 261 1.8E-17 T 28-03-2018 AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 SUPERFAMILY SSF53850 4 257 1.03E-67 T 28-03-2018 AFA_RS05140 457a97e9f2834e40bf8755d2c8f6a0c5 264 Gene3D G3DSA:3.40.190.10 18 142 3.9E-36 T 28-03-2018 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 174 4.5E-22 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Gene3D G3DSA:2.40.240.10 1 93 1.3E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 9.0E-35 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 28.317 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 173 1.2E-39 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Gene3D G3DSA:2.170.120.20 97 186 5.1E-22 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Pfam PF01386 Ribosomal L25p family 4 90 1.5E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 SUPERFAMILY SSF50715 1 180 2.62E-49 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS02815 08ec70b6cbd29693bf6c9e62fab36267 199 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 23.211 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 SUPERFAMILY SSF53720 18 490 8.38E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 39 485 1.3E-211 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 Gene3D G3DSA:3.40.309.10 282 473 1.3E-73 T 28-03-2018 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 Pfam PF00171 Aldehyde dehydrogenase family 28 486 1.3E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS13855 b0a8343a7b5a1571af77cf2f09f2da7f 491 Gene3D G3DSA:3.40.605.10 18 281 2.2E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 Gene3D G3DSA:3.40.50.620 2 178 1.0E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 6.1E-160 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 Gene3D G3DSA:3.90.1260.10 179 374 2.4E-57 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 SUPERFAMILY SSF52402 5 185 1.75E-33 T 28-03-2018 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 Gene3D G3DSA:1.10.287.400 378 437 4.4E-28 T 28-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 Pfam PF00764 Arginosuccinate synthase 16 410 1.2E-58 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 443 70.335 T 28-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFA_RS07250 9b6945fba04e1da0e7a4b6cb3e4e8337 444 SUPERFAMILY SSF69864 190 442 4.58E-79 T 28-03-2018 AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Gene3D G3DSA:3.40.350.10 157 301 2.9E-23 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Pfam PF01321 Creatinase/Prolidase N-terminal domain 9 139 1.6E-15 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Gene3D G3DSA:3.40.350.10 2 148 1.3E-39 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Pfam PF16188 C-terminal region of peptidase_M24 532 592 8.0E-25 T 28-03-2018 IPR032416 Peptidase M24, C-terminal domain AFA_RS12920 91143b3f93b4329aa916addc07995778 592 SUPERFAMILY SSF53092 42 142 1.71E-10 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Pfam PF16189 Creatinase/Prolidase N-terminal domain 150 307 3.2E-38 T 28-03-2018 AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Gene3D G3DSA:3.90.230.10 302 552 5.2E-62 T 28-03-2018 AFA_RS12920 91143b3f93b4329aa916addc07995778 592 Pfam PF00557 Metallopeptidase family M24 310 520 4.1E-42 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS12920 91143b3f93b4329aa916addc07995778 592 SUPERFAMILY SSF55920 304 558 4.19E-53 T 28-03-2018 IPR000994 Peptidase M24 AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 Pfam PF02016 LD-carboxypeptidase 28 302 3.8E-69 T 28-03-2018 IPR003507 Peptidase family S66 AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 PIRSF PIRSF028757 22 319 4.0E-66 T 28-03-2018 IPR003507 Peptidase family S66 AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 Gene3D G3DSA:3.40.50.10740 22 172 1.1E-39 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 SUPERFAMILY SSF52317 25 173 3.62E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 Gene3D G3DSA:3.50.30.60 177 318 1.7E-39 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain AFA_RS10635 991d526180c2b95b4f5aa763dadc4b73 320 SUPERFAMILY SSF141986 157 309 1.27E-38 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain AFA_RS17230 dcb62ee0191f1de6605d191114c3e93a 141 SUPERFAMILY SSF101738 2 111 5.62E-43 T 28-03-2018 IPR007481 Stringent starvation protein B AFA_RS17230 dcb62ee0191f1de6605d191114c3e93a 141 PIRSF PIRSF005276 1 141 2.6E-47 T 28-03-2018 IPR007481 Stringent starvation protein B AFA_RS17230 dcb62ee0191f1de6605d191114c3e93a 141 Gene3D G3DSA:2.30.30.220 7 103 4.6E-35 T 28-03-2018 IPR007481 Stringent starvation protein B AFA_RS17230 dcb62ee0191f1de6605d191114c3e93a 141 Pfam PF04386 Stringent starvation protein B 5 129 7.7E-31 T 28-03-2018 IPR007481 Stringent starvation protein B AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SUPERFAMILY SSF55781 31 169 4.71E-24 T 28-03-2018 IPR029016 GAF domain-like AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SMART SM00091 175 241 1.5E-10 T 28-03-2018 IPR000014 PAS domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Pfam PF00563 EAL domain 474 708 1.3E-63 T 28-03-2018 IPR001633 EAL domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Pfam PF13426 PAS domain 185 290 1.2E-13 T 28-03-2018 IPR000014 PAS domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 172 298 2.0E-23 T 28-03-2018 IPR000014 PAS domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SMART SM00267 291 458 4.1E-58 T 28-03-2018 IPR000160 GGDEF domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SUPERFAMILY SSF141868 473 721 9.15E-81 T 28-03-2018 IPR001633 EAL domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Gene3D G3DSA:3.30.70.270 297 458 3.0E-52 T 28-03-2018 AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Gene3D G3DSA:3.30.450.40 23 169 9.9E-22 T 28-03-2018 IPR029016 GAF domain-like AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Pfam PF00990 Diguanylate cyclase, GGDEF domain 302 452 1.5E-40 T 28-03-2018 IPR000160 GGDEF domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Pfam PF01590 GAF domain 31 157 7.2E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SMART SM00086 251 291 6.0E-4 T 28-03-2018 IPR001610 PAC motif AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SUPERFAMILY SSF55073 307 460 6.28E-44 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Gene3D G3DSA:3.20.20.450 459 717 7.0E-88 T 28-03-2018 IPR001633 EAL domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SUPERFAMILY SSF55785 186 298 1.24E-25 T 28-03-2018 IPR000014 PAS domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SMART SM00065 28 171 1.9E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 301 457 4.6E-36 T 28-03-2018 IPR000160 GGDEF domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 SMART SM00052 468 713 4.7E-95 T 28-03-2018 IPR001633 EAL domain AFA_RS13820 a223b1aa695f65e07ec55e34b290c32b 749 Gene3D G3DSA:3.30.450.20 170 296 2.4E-24 T 28-03-2018 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 Gene3D G3DSA:3.50.50.60 312 369 9.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 Gene3D G3DSA:3.50.50.60 2 58 1.2E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 Pfam PF01266 FAD dependent oxidoreductase 6 362 8.9E-65 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 SUPERFAMILY SSF51905 5 321 9.06E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 Gene3D G3DSA:3.30.9.10 87 194 2.3E-21 T 28-03-2018 AFA_RS03485 3c937f473c94c035aec8dd3a67e3157d 371 Gene3D G3DSA:3.30.9.10 195 311 6.1E-26 T 28-03-2018 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 Gene3D G3DSA:1.10.10.60 221 274 6.1E-7 T 28-03-2018 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 Gene3D G3DSA:2.60.120.10 3 109 3.4E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 SUPERFAMILY SSF46689 217 263 6.09E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 Gene3D G3DSA:1.10.10.60 161 220 3.9E-9 T 28-03-2018 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 Pfam PF12833 Helix-turn-helix domain 187 263 4.0E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 Pfam PF02311 AraC-like ligand binding domain 29 109 1.2E-8 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 SMART SM00342 180 262 1.3E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 SUPERFAMILY SSF46689 163 215 1.88E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 258 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS08225 f58c0ff556761365de272813ae7e4ca3 278 SUPERFAMILY SSF51182 9 182 4.27E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS15015 336a02da34237ac36a90a65218de320f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 5.0E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS15015 336a02da34237ac36a90a65218de320f 304 Gene3D G3DSA:1.10.10.10 7 98 4.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15015 336a02da34237ac36a90a65218de320f 304 Gene3D G3DSA:3.40.190.10 189 270 8.3E-11 T 28-03-2018 AFA_RS15015 336a02da34237ac36a90a65218de320f 304 SUPERFAMILY SSF53850 93 300 1.05E-31 T 28-03-2018 AFA_RS15015 336a02da34237ac36a90a65218de320f 304 Gene3D G3DSA:3.40.190.10 99 188 2.9E-18 T 28-03-2018 AFA_RS15015 336a02da34237ac36a90a65218de320f 304 SUPERFAMILY SSF46785 6 116 1.63E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15015 336a02da34237ac36a90a65218de320f 304 Pfam PF03466 LysR substrate binding domain 93 298 9.2E-30 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS04350 705a6a9bc69f8aa4f4868d7d03758df5 106 SUPERFAMILY SSF88659 31 85 2.83E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS04350 705a6a9bc69f8aa4f4868d7d03758df5 106 Pfam PF08281 Sigma-70, region 4 33 84 4.7E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS04350 705a6a9bc69f8aa4f4868d7d03758df5 106 Gene3D G3DSA:1.10.10.10 15 90 6.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Gene3D G3DSA:1.10.730.10 668 822 5.1E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 576 586 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 543 565 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 1.3E-48 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Pfam PF08264 Anticodon-binding domain of tRNA 727 848 9.0E-16 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 590 1.2E-8 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Gene3D G3DSA:3.40.50.620 2 667 5.2E-148 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 SUPERFAMILY SSF52374 434 688 3.99E-145 T 28-03-2018 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 SUPERFAMILY SSF52374 4 233 3.99E-145 T 28-03-2018 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 885 22.265 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Pfam PF09334 tRNA synthetases class I (M) 44 177 2.1E-17 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 421 1.9E-64 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 884 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 SUPERFAMILY SSF47323 683 884 1.35E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS12835 17a3ad9918c8127c4ff58d3a420aa360 885 SUPERFAMILY SSF50677 233 433 1.67E-48 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 Gene3D G3DSA:3.40.50.1970 7 184 2.2E-35 T 28-03-2018 AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 352 3.4E-79 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 Gene3D G3DSA:1.20.1090.10 187 367 3.1E-40 T 28-03-2018 AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 TIGRFAM TIGR03405 Phn_Fe-ADH: phosphonate metabolism-associated iron-containing alcohol dehydrogenase 4 362 2.7E-136 T 28-03-2018 IPR017775 Alcohol dehydrogenase, iron-type, phosphonate metabolism-associated AFA_RS15350 9e8c3c838a609a72f50bbf3fff74adbf 370 SUPERFAMILY SSF56796 2 354 3.27E-80 T 28-03-2018 AFA_RS17710 4b8297a3ae4b7c978259648d15eb2c4a 166 Pfam PF00583 Acetyltransferase (GNAT) family 36 142 8.8E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS17710 4b8297a3ae4b7c978259648d15eb2c4a 166 SUPERFAMILY SSF55729 13 144 2.03E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS17710 4b8297a3ae4b7c978259648d15eb2c4a 166 Gene3D G3DSA:3.40.630.30 9 145 4.8E-24 T 28-03-2018 AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 SMART SM00490 1052 1130 1.3E-12 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 SMART SM00487 94 338 8.0E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 Gene3D G3DSA:3.40.50.300 69 324 1.3E-24 T 28-03-2018 AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 SUPERFAMILY SSF52540 1057 1147 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 SUPERFAMILY SSF52540 152 319 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 SUPERFAMILY SSF52540 640 664 2.2E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 Pfam PF00271 Helicase conserved C-terminal domain 1060 1129 4.6E-11 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 Gene3D G3DSA:3.40.50.300 636 1154 4.8E-25 T 28-03-2018 AFA_RS09815 da143d3313a12b2a28d9eb5f6c6bca08 2085 Pfam PF00270 DEAD/DEAH box helicase 102 304 7.6E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 Pfam PF00005 ABC transporter 21 163 1.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 Pfam PF08402 TOBE domain 268 339 4.1E-15 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 SUPERFAMILY SSF52540 6 244 1.68E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 SUPERFAMILY SSF50331 244 347 1.02E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 Gene3D G3DSA:2.40.50.140 271 331 1.3E-14 T 28-03-2018 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 Gene3D G3DSA:3.40.50.300 1 240 3.8E-72 T 28-03-2018 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS02265 f1df92afd8308d6924d2841efdc18ed7 364 SMART SM00382 30 213 1.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Gene3D G3DSA:3.40.50.300 250 517 2.7E-56 T 28-03-2018 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Pfam PF16326 ABC transporter C-terminal domain 534 599 6.8E-16 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 SUPERFAMILY SSF52540 5 198 3.09E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Pfam PF12848 ABC transporter 190 265 2.7E-10 T 28-03-2018 IPR032781 ABC-transporter extension domain AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 SUPERFAMILY SSF52540 279 494 1.43E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Gene3D G3DSA:3.40.50.300 6 249 8.3E-52 T 28-03-2018 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 SMART SM00382 30 196 4.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 SMART SM00382 310 480 4.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Gene3D G3DSA:3.90.20.10 532 602 0.0021 T 28-03-2018 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Pfam PF00005 ABC transporter 302 435 1.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03615 8f9d702f85694b0d8f15df43c3cec715 604 Pfam PF00005 ABC transporter 21 151 3.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.5E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 Gene3D G3DSA:3.40.190.10 90 208 8.6E-26 T 28-03-2018 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 Gene3D G3DSA:3.40.190.10 219 298 1.4E-7 T 28-03-2018 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 SUPERFAMILY SSF53850 90 297 4.96E-45 T 28-03-2018 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 SUPERFAMILY SSF46785 5 86 1.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 Pfam PF03466 LysR substrate binding domain 94 295 1.3E-27 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 7.1E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS01560 89dfde5b8388bda06a6f7f733e7bd93f 298 Gene3D G3DSA:1.10.10.10 3 87 6.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 SUPERFAMILY SSF81442 27 534 1.83E-196 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 480 1.6E-156 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 258 312 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 31 534 6.1E-219 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 302 317 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 256 277 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 9.9E-122 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17525 a1819a455b4b27904a6326b674bfe602 535 Gene3D G3DSA:1.20.210.10 26 535 5.5E-225 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 8 349 3.5E-132 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 Gene3D G3DSA:3.40.1780.10 177 349 9.0E-64 T 28-03-2018 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 Gene3D G3DSA:3.40.1780.10 2 124 8.2E-29 T 28-03-2018 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 SUPERFAMILY SSF111337 8 349 1.18E-129 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 350 45.284 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFA_RS03255 dabb4e82662d9f5a8f32b164de8b40d6 354 Pfam PF02547 Queuosine biosynthesis protein 10 349 5.5E-132 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFA_RS10605 8c16cbb908ca1fdc0fc3c5cf969b9e8c 430 PIRSF PIRSF005353 1 430 1.4E-177 T 28-03-2018 IPR026033 Purine permease PbuG-like AFA_RS10605 8c16cbb908ca1fdc0fc3c5cf969b9e8c 430 Pfam PF00860 Permease family 18 388 1.6E-54 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS09715 0af092d64fcecc07b3657cc424b5d2f0 106 Gene3D G3DSA:4.10.430.10 66 103 1.7E-14 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS09715 0af092d64fcecc07b3657cc424b5d2f0 106 SMART SM00528 60 103 8.1E-11 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS09715 0af092d64fcecc07b3657cc424b5d2f0 106 SUPERFAMILY SSF81273 65 104 1.02E-10 T 28-03-2018 AFA_RS09715 0af092d64fcecc07b3657cc424b5d2f0 106 Pfam PF00816 H-NS histone family 10 96 4.2E-21 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 Pfam PF01047 MarR family 35 93 1.4E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 SMART SM00529 53 148 0.0092 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 SMART SM00347 27 128 4.8E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 8.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 8.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 8.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 SUPERFAMILY SSF46785 6 144 8.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12635 46788b1e3179d3e81bf4ed82d43dec04 175 Gene3D G3DSA:1.10.10.10 1 146 3.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Gene3D G3DSA:3.40.50.980 23 217 3.6E-43 T 28-03-2018 AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Gene3D G3DSA:3.40.50.980 218 375 2.7E-44 T 28-03-2018 AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 SUPERFAMILY SSF56801 11 560 6.28E-147 T 28-03-2018 AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Gene3D G3DSA:2.30.38.10 376 458 7.5E-28 T 28-03-2018 AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 548 4.7E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Pfam PF00501 AMP-binding enzyme 34 465 2.5E-106 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS03735 e651ddab9479493dfea02c413ebde130 565 Gene3D G3DSA:3.30.300.30 459 564 7.6E-28 T 28-03-2018 AFA_RS08035 b53c780d0f9a4a365bdbe398deeee034 154 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 40 115 1.8E-32 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS08035 b53c780d0f9a4a365bdbe398deeee034 154 SUPERFAMILY SSF141734 17 122 7.59E-42 T 28-03-2018 AFA_RS08035 b53c780d0f9a4a365bdbe398deeee034 154 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 14 119 28.193 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS08035 b53c780d0f9a4a365bdbe398deeee034 154 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 63 118 6.0E-20 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS06540 921c429327d0aa68d4e96aec37088f43 202 Pfam PF00857 Isochorismatase family 7 181 1.1E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS06540 921c429327d0aa68d4e96aec37088f43 202 Gene3D G3DSA:3.40.50.850 1 190 3.3E-38 T 28-03-2018 AFA_RS06540 921c429327d0aa68d4e96aec37088f43 202 SUPERFAMILY SSF52499 5 181 1.57E-42 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS06240 322ade7e4840d45e77c65b1dac2670a7 167 PIRSF PIRSF010312 8 167 3.0E-29 T 28-03-2018 IPR016568 Sulphur oxidation, SoxY AFA_RS06240 322ade7e4840d45e77c65b1dac2670a7 167 Gene3D G3DSA:2.60.40.730 55 161 1.1E-5 T 28-03-2018 AFA_RS06240 322ade7e4840d45e77c65b1dac2670a7 167 Pfam PF13501 Sulfur oxidation protein SoxY 58 165 2.0E-26 T 28-03-2018 IPR032711 Ig-like SoxY domain AFA_RS18455 3034126f5daf1028fb669b69506bdc16 117 SUPERFAMILY SSF46785 35 86 7.14E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18455 3034126f5daf1028fb669b69506bdc16 117 Gene3D G3DSA:1.10.10.10 3 117 7.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 SMART SM00316 37 118 1.0E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 Pfam PF10150 Ribonuclease E/G family 120 389 8.1E-92 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 2.6E-155 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 Gene3D G3DSA:2.40.50.140 32 123 1.4E-28 T 28-03-2018 AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 SUPERFAMILY SSF50249 39 124 3.81E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 Pfam PF00575 S1 RNA binding domain 36 117 9.4E-9 T 28-03-2018 IPR003029 S1 domain GO:0003676 AFA_RS13175 bfe16c40b77f91c673b5ded38e451cc9 1107 Hamap MF_00970 Ribonuclease E [rne]. 1 1020 34.583 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 Pfam PF04851 Type III restriction enzyme, res subunit 297 498 3.2E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 Gene3D G3DSA:3.40.50.300 282 511 1.6E-23 T 28-03-2018 AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 SMART SM00487 292 527 4.3E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 14 213 1.9E-11 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 Gene3D G3DSA:3.40.50.300 577 757 0.0012 T 28-03-2018 AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 SUPERFAMILY SSF52540 486 550 1.02E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12295 ae8ef1381a6864a7d7e867a6bdfd80bf 1085 SUPERFAMILY SSF52540 262 458 1.02E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11140 3d2112de85d561df99c4792579395d88 379 SUPERFAMILY SSF47384 128 210 1.24E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 6.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 6.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 6.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 Gene3D G3DSA:1.10.287.130 135 206 3.6E-11 T 28-03-2018 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 209 6.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS11140 3d2112de85d561df99c4792579395d88 379 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 362 5.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11140 3d2112de85d561df99c4792579395d88 379 SMART SM00387 257 365 2.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11140 3d2112de85d561df99c4792579395d88 379 SUPERFAMILY SSF55874 200 362 1.57E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11140 3d2112de85d561df99c4792579395d88 379 Gene3D G3DSA:3.30.565.10 217 365 3.2E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS11140 3d2112de85d561df99c4792579395d88 379 SMART SM00388 145 210 9.4E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS13675 ed998eb934f2e83c0922730d89d15537 386 SUPERFAMILY SSF52540 107 364 2.61E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13675 ed998eb934f2e83c0922730d89d15537 386 Gene3D G3DSA:3.40.50.300 99 364 1.1E-26 T 28-03-2018 AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 2.5E-39 T 28-03-2018 AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 8.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.9E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 Gene3D G3DSA:3.40.50.720 1 257 1.0E-48 T 28-03-2018 AFA_RS02485 83e4721d872a2e1921daca4ae7ae270a 257 SUPERFAMILY SSF51735 5 256 3.36E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14050 a49cb02c2bb4927678a02983523a6164 224 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 17 206 2.0E-58 T 28-03-2018 IPR003744 Queuosine precursor transporter AFA_RS14050 a49cb02c2bb4927678a02983523a6164 224 Pfam PF02592 Putative vitamin uptake transporter 45 202 4.1E-39 T 28-03-2018 IPR003744 Queuosine precursor transporter AFA_RS04060 7179af90f697828595c91b02d191b290 226 Gene3D G3DSA:1.10.3720.10 1 224 8.5E-38 T 28-03-2018 AFA_RS04060 7179af90f697828595c91b02d191b290 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 217 9.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04060 7179af90f697828595c91b02d191b290 226 SUPERFAMILY SSF161098 3 211 2.22E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04060 7179af90f697828595c91b02d191b290 226 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 215 2.2E-72 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 AFA_RS16920 2a1cfc3f7fe70f6c0a2bd59776650e4d 303 SMART SM00382 35 215 8.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16920 2a1cfc3f7fe70f6c0a2bd59776650e4d 303 SUPERFAMILY SSF52540 12 229 4.82E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16920 2a1cfc3f7fe70f6c0a2bd59776650e4d 303 Gene3D G3DSA:3.40.50.300 9 285 3.9E-63 T 28-03-2018 AFA_RS16920 2a1cfc3f7fe70f6c0a2bd59776650e4d 303 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS16920 2a1cfc3f7fe70f6c0a2bd59776650e4d 303 Pfam PF00005 ABC transporter 27 166 1.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04600 6ed8d4f6ae4c8977c05093020192666f 356 SUPERFAMILY SSF56317 5 306 9.42E-68 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS04600 6ed8d4f6ae4c8977c05093020192666f 356 Pfam PF00795 Carbon-nitrogen hydrolase 8 286 2.6E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS04600 6ed8d4f6ae4c8977c05093020192666f 356 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 159 172 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 AFA_RS04600 6ed8d4f6ae4c8977c05093020192666f 356 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 AFA_RS04600 6ed8d4f6ae4c8977c05093020192666f 356 Gene3D G3DSA:3.60.110.10 1 322 4.5E-58 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 SUPERFAMILY SSF54373 269 360 5.62E-14 T 28-03-2018 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 SUPERFAMILY SSF51905 107 271 1.42E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 SUPERFAMILY SSF51905 1 54 1.42E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 SUPERFAMILY SSF51905 360 416 1.42E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 46.996 T 28-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 Gene3D G3DSA:3.40.50.720 1 113 5.5E-6 T 28-03-2018 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 Pfam PF01266 FAD dependent oxidoreductase 2 398 2.0E-69 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 Gene3D G3DSA:3.30.9.10 134 215 3.8E-10 T 28-03-2018 AFA_RS15785 da09d39d3021572a9de5579aac70736b 417 Gene3D G3DSA:3.30.9.10 216 358 1.3E-20 T 28-03-2018 AFA_RS13215 e47cc0c90c98d6bb42c84e436de3f00b 407 Pfam PF06850 PHB de-polymerase C-terminus 205 406 1.3E-93 T 28-03-2018 IPR009656 PHB de-polymerase, C-terminal AFA_RS13215 e47cc0c90c98d6bb42c84e436de3f00b 407 PIRSF PIRSF020818 1 407 2.9E-195 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase AFA_RS13215 e47cc0c90c98d6bb42c84e436de3f00b 407 SUPERFAMILY SSF53474 90 404 4.48E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13215 e47cc0c90c98d6bb42c84e436de3f00b 407 Gene3D G3DSA:3.40.50.1820 65 407 4.3E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13215 e47cc0c90c98d6bb42c84e436de3f00b 407 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 405 3.3E-180 T 28-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase AFA_RS10765 a3cd49b5fa338e4d05ea6fdf63749bf6 220 SUPERFAMILY SSF51366 5 216 1.73E-52 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS10765 a3cd49b5fa338e4d05ea6fdf63749bf6 220 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 7 214 3.8E-39 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFA_RS10765 a3cd49b5fa338e4d05ea6fdf63749bf6 220 Gene3D G3DSA:3.20.20.70 4 218 1.7E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS10765 a3cd49b5fa338e4d05ea6fdf63749bf6 220 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 5 219 35.489 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 Gene3D G3DSA:2.30.30.40 66 121 5.2E-5 T 28-03-2018 AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 Gene3D G3DSA:2.30.30.40 1 65 1.8E-4 T 28-03-2018 AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 SUPERFAMILY SSF50044 67 117 3.07E-7 T 28-03-2018 IPR001452 SH3 domain GO:0005515 AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 Pfam PF07653 Variant SH3 domain 10 58 9.8E-6 T 28-03-2018 IPR011511 Variant SH3 domain AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 SUPERFAMILY SSF50044 2 68 1.34E-6 T 28-03-2018 IPR001452 SH3 domain GO:0005515 AFA_RS10005 08ac9dfa1e9dd6f4e4b9123e9de60e3c 121 PIRSF PIRSF034961 1 117 9.5E-37 T 28-03-2018 IPR014593 Uncharacterised conserved protein UCP034961, SH3-2 AFA_RS02175 571079db50bcea0c18db8c0838f935d8 333 PIRSF PIRSF031853 1 333 3.8E-115 T 28-03-2018 IPR016984 Uncharacterised conserved protein UCP031853 AFA_RS02175 571079db50bcea0c18db8c0838f935d8 333 Gene3D G3DSA:3.40.1350.10 186 318 1.7E-22 T 28-03-2018 AFA_RS02175 571079db50bcea0c18db8c0838f935d8 333 SUPERFAMILY SSF52980 200 310 1.93E-12 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS02175 571079db50bcea0c18db8c0838f935d8 333 Pfam PF04471 Restriction endonuclease 198 309 6.9E-24 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFA_RS03375 66135abcf8702ae10c7d5440200df75a 155 Gene3D G3DSA:3.30.370.10 36 130 1.4E-14 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) AFA_RS03375 66135abcf8702ae10c7d5440200df75a 155 SUPERFAMILY SSF52038 39 122 2.75E-16 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) AFA_RS03375 66135abcf8702ae10c7d5440200df75a 155 Pfam PF01337 Barstar (barnase inhibitor) 41 118 9.0E-20 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) AFA_RS01435 85baf97a4fa969d260377fd4ac8787d0 416 SUPERFAMILY SSF103473 17 401 6.02E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS01435 85baf97a4fa969d260377fd4ac8787d0 416 Gene3D G3DSA:1.20.1250.20 213 401 2.4E-13 T 28-03-2018 AFA_RS01435 85baf97a4fa969d260377fd4ac8787d0 416 Gene3D G3DSA:1.20.1250.20 12 212 4.9E-22 T 28-03-2018 AFA_RS01435 85baf97a4fa969d260377fd4ac8787d0 416 Pfam PF05977 Transmembrane secretion effector 15 411 2.0E-35 T 28-03-2018 IPR010290 Transmembrane secretion effector AFA_RS04655 527b60c5b415df041dd66b2ca707e85f 127 Gene3D G3DSA:3.30.1450.10 38 127 2.1E-6 T 28-03-2018 AFA_RS12370 395bbabd22d03b0b348ebbbb58d04f59 89 Gene3D G3DSA:3.30.240.10 15 86 5.7E-15 T 28-03-2018 AFA_RS12370 395bbabd22d03b0b348ebbbb58d04f59 89 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 19 81 1.3E-24 T 28-03-2018 IPR031856 Putative bacterial antitoxin YdaS AFA_RS12370 395bbabd22d03b0b348ebbbb58d04f59 89 SUPERFAMILY SSF47413 19 78 6.76E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 27 183 1.1E-53 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 Pfam PF01048 Phosphorylase superfamily 287 445 4.7E-11 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 Gene3D G3DSA:3.40.50.1580 190 482 4.7E-61 T 28-03-2018 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 SUPERFAMILY SSF53167 24 500 1.1E-143 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 Hamap MF_01932 AMP nucleosidase [amn]. 18 500 60.216 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 Gene3D G3DSA:3.30.1730.10 21 184 1.1E-57 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 AFA_RS00590 49d028e77f5c8a1ff8e9bb1d2e99be7b 500 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 27 500 1.1E-205 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 SMART SM00448 1 115 6.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 Gene3D G3DSA:1.10.10.10 124 222 4.3E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 SUPERFAMILY SSF52172 1 178 6.64E-37 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 Pfam PF00072 Response regulator receiver domain 3 115 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 2.6E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 Gene3D G3DSA:3.40.50.2300 1 123 9.5E-33 T 28-03-2018 AFA_RS15420 8a94319859902587aeff63bf36b810bf 222 SMART SM00862 148 219 1.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 Gene3D G3DSA:1.10.10.10 159 242 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 Pfam PF13545 Crp-like helix-turn-helix domain 162 235 1.7E-18 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 SUPERFAMILY SSF46785 161 238 1.91E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 SMART SM00100 24 142 1.8E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 SUPERFAMILY SSF51206 17 156 1.57E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 SMART SM00419 181 229 1.3E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 Gene3D G3DSA:2.60.120.10 17 158 4.5E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 ProSitePatterns PS00042 Crp-type HTH domain signature. 189 212 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 1.5E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 1.5E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFA_RS11725 80529e9cc4d052e36d5ec9dc91f9ae22 242 Pfam PF00027 Cyclic nucleotide-binding domain 44 127 4.1E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS09240 fc831885b3acf73d33f35b0e23308bad 412 SUPERFAMILY SSF103473 14 407 2.49E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS09240 fc831885b3acf73d33f35b0e23308bad 412 Gene3D G3DSA:1.20.1250.20 215 406 2.6E-18 T 28-03-2018 AFA_RS09240 fc831885b3acf73d33f35b0e23308bad 412 Pfam PF07690 Major Facilitator Superfamily 30 258 1.5E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS09240 fc831885b3acf73d33f35b0e23308bad 412 Gene3D G3DSA:1.20.1250.20 17 214 3.4E-22 T 28-03-2018 AFA_RS01650 05fb50a579bf624c5a6fb60c6196ecd4 253 Gene3D G3DSA:3.40.50.300 1 221 9.7E-57 T 28-03-2018 AFA_RS01650 05fb50a579bf624c5a6fb60c6196ecd4 253 SMART SM00382 31 221 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01650 05fb50a579bf624c5a6fb60c6196ecd4 253 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01650 05fb50a579bf624c5a6fb60c6196ecd4 253 Pfam PF00005 ABC transporter 22 161 2.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01650 05fb50a579bf624c5a6fb60c6196ecd4 253 SUPERFAMILY SSF52540 2 226 2.74E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04620 8a3dc6b8ef3bd006d61a45c21ac6afb6 334 Pfam PF13343 Bacterial extracellular solute-binding protein 78 308 1.2E-31 T 28-03-2018 AFA_RS04620 8a3dc6b8ef3bd006d61a45c21ac6afb6 334 PIRSF PIRSF002825 5 330 1.2E-64 T 28-03-2018 IPR026045 Ferric binding protein AFA_RS04620 8a3dc6b8ef3bd006d61a45c21ac6afb6 334 Gene3D G3DSA:3.40.190.10 28 138 0.057 T 28-03-2018 AFA_RS04620 8a3dc6b8ef3bd006d61a45c21ac6afb6 334 SUPERFAMILY SSF53850 35 327 1.89E-51 T 28-03-2018 AFA_RS04620 8a3dc6b8ef3bd006d61a45c21ac6afb6 334 Gene3D G3DSA:3.40.190.10 139 276 2.4E-30 T 28-03-2018 AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 Pfam PF14331 ImcF-related N-terminal domain 167 350 7.4E-34 T 28-03-2018 IPR025743 ImcF-related, N-terminal domain AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 Pfam PF05036 Sporulation related domain 1254 1320 1.4E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 Gene3D G3DSA:3.30.70.1070 1167 1268 0.022 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 Gene3D G3DSA:3.30.70.1070 1269 1323 3.7E-4 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 Gene3D G3DSA:1.20.1170.10 200 1166 0.0052 T 28-03-2018 AFA_RS09890 098a9a881195a50d72e56a829778f839 1330 SUPERFAMILY SSF110997 1253 1318 2.09E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 Gene3D G3DSA:1.20.120.530 74 223 1.3E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 SUPERFAMILY SSF48008 83 214 9.94E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 Gene3D G3DSA:1.10.10.10 2 73 6.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 SMART SM00895 87 207 7.0E-19 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 SMART SM00345 19 77 2.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 Pfam PF07729 FCD domain 88 206 2.2E-22 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 SUPERFAMILY SSF46785 12 81 8.56E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00060 3fd26a2c0852525d80153c3259402fa1 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 2.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14535 01a0ad5f0052f5e0a70452499ed6a713 176 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 2 159 35.075 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFA_RS14535 01a0ad5f0052f5e0a70452499ed6a713 176 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 154 1.2E-55 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFA_RS14535 01a0ad5f0052f5e0a70452499ed6a713 176 SUPERFAMILY SSF55068 3 166 8.76E-70 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFA_RS14535 01a0ad5f0052f5e0a70452499ed6a713 176 Pfam PF01625 Peptide methionine sulfoxide reductase 4 155 2.8E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFA_RS14535 01a0ad5f0052f5e0a70452499ed6a713 176 Gene3D G3DSA:3.30.1060.10 1 167 2.4E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFA_RS13710 9d1c9ef74eae81c370203edc61863023 500 Pfam PF08479 POTRA domain, ShlB-type 3 76 6.4E-19 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type AFA_RS13710 9d1c9ef74eae81c370203edc61863023 500 Gene3D G3DSA:3.10.20.310 5 76 4.1E-15 T 28-03-2018 AFA_RS13710 9d1c9ef74eae81c370203edc61863023 500 Gene3D G3DSA:2.40.160.50 106 494 2.4E-37 T 28-03-2018 AFA_RS13710 9d1c9ef74eae81c370203edc61863023 500 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 139 459 5.8E-15 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 PRINTS PR00811 Bacterial general secretion pathway protein D signature 213 237 1.6E-11 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 PRINTS PR00811 Bacterial general secretion pathway protein D signature 140 150 1.6E-11 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 PRINTS PR00811 Bacterial general secretion pathway protein D signature 338 356 1.6E-11 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 PRINTS PR00811 Bacterial general secretion pathway protein D signature 361 375 1.6E-11 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 Pfam PF13629 Pilus formation protein N terminal region 5 73 3.2E-13 T 28-03-2018 IPR032789 Pilus formation protein, N-terminal AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 319 352 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 AFA_RS10895 331aec5b1a576d17c742fab39eb6ab9c 432 Pfam PF00263 Bacterial type II and III secretion system protein 217 373 9.7E-42 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 SUPERFAMILY SSF53098 1 174 1.09E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 Pfam PF00929 Exonuclease 4 163 1.5E-28 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 176 4.1E-54 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 SMART SM00479 2 174 5.8E-44 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 Gene3D G3DSA:3.30.420.10 2 178 2.7E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS15180 5ddd6454f1489a9f034d049dda7b06ba 241 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 232 7.6E-84 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS01780 e46f5ea6765350423612ec222b64a19f 323 Gene3D G3DSA:3.20.20.70 9 323 2.0E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01780 e46f5ea6765350423612ec222b64a19f 323 SUPERFAMILY SSF51412 11 297 4.21E-58 T 28-03-2018 AFA_RS01780 e46f5ea6765350423612ec222b64a19f 323 Pfam PF03060 Nitronate monooxygenase 15 306 1.1E-22 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFA_RS12655 fb542e6ca8216bf1f6658686e37c720d 115 SMART SM00528 70 114 3.0E-13 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS12655 fb542e6ca8216bf1f6658686e37c720d 115 Pfam PF00816 H-NS histone family 12 108 2.9E-23 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 AFA_RS12655 fb542e6ca8216bf1f6658686e37c720d 115 SUPERFAMILY SSF81273 73 114 2.08E-11 T 28-03-2018 AFA_RS12655 fb542e6ca8216bf1f6658686e37c720d 115 Gene3D G3DSA:4.10.430.10 76 114 2.2E-18 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS15815 9c173c032a0ad5c3246a1a8d71ce71f2 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 1.1E-79 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS15815 9c173c032a0ad5c3246a1a8d71ce71f2 329 PIRSF PIRSF017082 1 327 6.3E-74 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS15815 9c173c032a0ad5c3246a1a8d71ce71f2 329 SUPERFAMILY SSF53850 114 290 1.55E-9 T 28-03-2018 AFA_RS15815 9c173c032a0ad5c3246a1a8d71ce71f2 329 Gene3D G3DSA:3.40.190.10 126 257 6.3E-9 T 28-03-2018 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 SUPERFAMILY SSF51391 119 331 7.59E-37 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 TIGRFAM TIGR00586 mutt: mutator mutT protein 5 109 5.4E-31 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 Gene3D G3DSA:3.90.79.10 4 130 2.4E-28 T 28-03-2018 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 Pfam PF02581 Thiamine monophosphate synthase 147 325 2.4E-32 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 Pfam PF00293 NUDIX domain 8 110 2.5E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 SUPERFAMILY SSF55811 2 116 2.84E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS16045 fb342bdbffbafb4774f06c60f3beb1f7 333 Gene3D G3DSA:3.20.20.70 131 331 2.6E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01155 4b4d8f245ee27028ec62347fd439e532 451 SUPERFAMILY SSF75304 3 449 4.97E-120 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS01155 4b4d8f245ee27028ec62347fd439e532 451 Gene3D G3DSA:3.90.1300.10 1 451 7.8E-125 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS01155 4b4d8f245ee27028ec62347fd439e532 451 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFA_RS01155 4b4d8f245ee27028ec62347fd439e532 451 Pfam PF01425 Amidase 21 436 7.3E-87 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 PRINTS PR01008 Flagellar L-ring protein signature 205 219 5.0E-27 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 PRINTS PR01008 Flagellar L-ring protein signature 70 82 5.0E-27 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 PRINTS PR01008 Flagellar L-ring protein signature 142 157 5.0E-27 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 PRINTS PR01008 Flagellar L-ring protein signature 168 184 5.0E-27 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 PRINTS PR01008 Flagellar L-ring protein signature 189 203 5.0E-27 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 Hamap MF_00415 Flagellar L-ring protein [flgH]. 2 226 26.256 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS05850 ac92e90aa5ab9cce64f98a7589b0f97d 228 Pfam PF02107 Flagellar L-ring protein 47 227 2.9E-58 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 AFA_RS15680 4ad14b5629a403c904892e3d3b817a78 289 SUPERFAMILY SSF74653 173 279 2.22E-13 T 28-03-2018 AFA_RS15680 4ad14b5629a403c904892e3d3b817a78 289 Pfam PF13103 TonB C terminal 186 260 9.2E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 AFA_RS15680 4ad14b5629a403c904892e3d3b817a78 289 Gene3D G3DSA:3.30.1150.10 97 287 2.5E-15 T 28-03-2018 AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 60 20.604 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 2.1E-18 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 SUPERFAMILY SSF55129 4 60 1.96E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 PIRSF PIRSF002211 1 61 1.6E-26 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 60 1.5E-24 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site AFA_RS18010 1f4ace134e52635f4b6163c3732f5b61 61 Gene3D G3DSA:3.30.1390.20 6 60 8.0E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 Pfam PF13533 Biotin-lipoyl like 51 99 6.5E-12 T 28-03-2018 AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 Gene3D G3DSA:1.20.1600.10 57 304 2.7E-15 T 28-03-2018 AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 Pfam PF13437 HlyD family secretion protein 214 296 1.3E-9 T 28-03-2018 AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 SUPERFAMILY SSF111369 49 114 1.19E-9 T 28-03-2018 AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 SUPERFAMILY SSF111369 190 289 1.11E-8 T 28-03-2018 AFA_RS06445 e1b53f6adddd905a8f5658a5f5140068 349 SUPERFAMILY SSF111369 125 158 1.11E-8 T 28-03-2018 AFA_RS18200 aab8e8fd278be8f4b14ab351d1bc3a00 398 Gene3D G3DSA:3.40.190.10 39 137 9.2E-11 T 28-03-2018 AFA_RS18200 aab8e8fd278be8f4b14ab351d1bc3a00 398 Pfam PF13379 NMT1-like family 40 278 6.3E-47 T 28-03-2018 AFA_RS18200 aab8e8fd278be8f4b14ab351d1bc3a00 398 SUPERFAMILY SSF53850 42 275 7.76E-37 T 28-03-2018 AFA_RS18200 aab8e8fd278be8f4b14ab351d1bc3a00 398 Gene3D G3DSA:3.40.190.10 138 329 7.2E-29 T 28-03-2018 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 Gene3D G3DSA:2.102.10.10 39 147 3.5E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 Gene3D G3DSA:3.90.380.10 148 452 1.2E-70 T 28-03-2018 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 162 431 3.3E-42 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 SUPERFAMILY SSF50022 11 157 2.62E-51 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 26 51 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 56 71 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 77 97 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 142 168 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 98 118 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 183 205 2.5E-62 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 SUPERFAMILY SSF55961 159 440 2.9E-62 T 28-03-2018 AFA_RS13905 3ea2d6afa98c2ac820d4b93d8d7deea5 452 Pfam PF00355 Rieske [2Fe-2S] domain 41 124 7.5E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 SUPERFAMILY SSF56801 9 539 7.06E-140 T 28-03-2018 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Gene3D G3DSA:3.30.300.30 439 541 3.6E-29 T 28-03-2018 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 530 1.0E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Gene3D G3DSA:2.30.38.10 351 436 1.4E-20 T 28-03-2018 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Pfam PF00501 AMP-binding enzyme 38 442 5.5E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Gene3D G3DSA:3.40.50.980 21 197 4.4E-37 T 28-03-2018 AFA_RS04220 7b8c6717bdade5ed27dbdf06b0aefef9 541 Gene3D G3DSA:3.40.50.980 198 350 2.1E-34 T 28-03-2018 AFA_RS01655 22a159b419f830147b2bd20c2e02efce 337 SUPERFAMILY SSF53850 37 261 1.19E-40 T 28-03-2018 AFA_RS01655 22a159b419f830147b2bd20c2e02efce 337 Pfam PF09084 NMT1/THI5 like 40 255 2.3E-41 T 28-03-2018 IPR015168 SsuA/THI5-like AFA_RS01655 22a159b419f830147b2bd20c2e02efce 337 Gene3D G3DSA:3.40.190.10 128 332 7.2E-29 T 28-03-2018 AFA_RS01655 22a159b419f830147b2bd20c2e02efce 337 Gene3D G3DSA:3.40.190.10 25 126 6.0E-12 T 28-03-2018 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 214 255 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 SMART SM00342 177 259 2.2E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 SUPERFAMILY SSF46689 214 261 2.73E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 Gene3D G3DSA:1.10.10.60 218 262 2.0E-11 T 28-03-2018 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 Pfam PF12833 Helix-turn-helix domain 183 260 3.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 Pfam PF02311 AraC-like ligand binding domain 26 135 1.1E-5 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 Gene3D G3DSA:2.60.120.280 20 177 7.3E-7 T 28-03-2018 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 SUPERFAMILY SSF51182 17 188 5.07E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 Gene3D G3DSA:1.10.10.60 178 217 1.0E-6 T 28-03-2018 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 2.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS08075 761e5bca33e651d5be08b35a81499a7f 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 2.0E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 SUPERFAMILY SSF53187 342 433 1.86E-76 T 28-03-2018 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 SUPERFAMILY SSF53187 29 240 1.86E-76 T 28-03-2018 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 SUPERFAMILY SSF55031 228 333 3.44E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 Gene3D G3DSA:3.40.630.10 14 268 6.3E-48 T 28-03-2018 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 Gene3D G3DSA:3.40.630.10 292 437 1.1E-14 T 28-03-2018 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 Pfam PF07687 Peptidase dimerisation domain 230 327 4.2E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 43 419 1.9E-100 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 PIRSF PIRSF005962 27 435 1.2E-112 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 AFA_RS09225 fa4f3bebd79c4af7b23b678922249964 437 Pfam PF01546 Peptidase family M20/M25/M40 101 424 5.2E-28 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82693 267 323 9.16E-22 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82693 135 181 9.16E-22 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82866 291 490 3.53E-50 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Pfam PF00873 AcrB/AcrD/AcrF family 4 1004 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82714 700 785 6.67E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:3.30.70.1430 556 651 8.0E-16 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82693 554 649 7.85E-23 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 604 618 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.2E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82714 182 264 3.14E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:3.30.2090.10 181 264 6.5E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:3.30.2090.10 699 785 6.4E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:3.30.70.1430 40 141 2.6E-30 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82693 40 134 3.66E-26 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 SUPERFAMILY SSF82866 786 1007 7.19E-49 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:1.20.1640.10 786 1007 3.3E-44 T 28-03-2018 AFA_RS15185 64ed97352c287e5fe547bd304c0a7dc5 1025 Gene3D G3DSA:1.20.1640.10 265 491 4.5E-48 T 28-03-2018 AFA_RS00530 40a333d6b4d694794c31e683000fdd8e 285 Gene3D G3DSA:3.20.20.140 1 285 8.7E-35 T 28-03-2018 AFA_RS00530 40a333d6b4d694794c31e683000fdd8e 285 Pfam PF04909 Amidohydrolase 99 282 1.5E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS00530 40a333d6b4d694794c31e683000fdd8e 285 SUPERFAMILY SSF51556 4 284 1.3E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS09305 9de2e20ac125d6664101d9520f330fa1 153 Pfam PF13673 Acetyltransferase (GNAT) domain 54 147 9.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS09305 9de2e20ac125d6664101d9520f330fa1 153 Gene3D G3DSA:3.40.630.30 3 151 8.3E-29 T 28-03-2018 AFA_RS09305 9de2e20ac125d6664101d9520f330fa1 153 SUPERFAMILY SSF55729 3 148 2.47E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 Gene3D G3DSA:3.30.465.10 109 253 3.8E-37 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 Gene3D G3DSA:3.30.43.10 9 108 4.6E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 59 470 8.5E-174 T 28-03-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 SUPERFAMILY SSF56176 20 231 5.61E-65 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 SUPERFAMILY SSF55103 204 474 2.29E-76 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 Pfam PF02913 FAD linked oxidases, C-terminal domain 232 470 3.2E-70 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 Gene3D G3DSA:1.10.45.10 432 470 6.9E-11 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFA_RS05490 f3e695f267b6eee5a38ffc41321f3348 499 Pfam PF01565 FAD binding domain 56 192 1.2E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 Pfam PF00753 Metallo-beta-lactamase superfamily 549 637 1.9E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 Gene3D G3DSA:3.60.15.10 545 779 4.1E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 SUPERFAMILY SSF56281 540 816 4.59E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 Pfam PF03772 Competence protein 230 514 7.3E-47 T 28-03-2018 IPR004477 ComEC/Rec2-related protein AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 Pfam PF13567 Domain of unknown function (DUF4131) 26 186 4.9E-16 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 SMART SM00849 552 738 1.0E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 252 439 3.4E-14 T 28-03-2018 IPR004477 ComEC/Rec2-related protein AFA_RS07805 a0401ab1dcd2dada69303f6d54bf8479 822 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 146 792 4.0E-86 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 AFA_RS07420 08185a94691628a14a3a2a346ecaace7 379 Pfam PF04403 Paraquat-inducible protein A 1 147 1.1E-25 T 28-03-2018 IPR007498 Paraquat-inducible protein A AFA_RS07420 08185a94691628a14a3a2a346ecaace7 379 Pfam PF04403 Paraquat-inducible protein A 203 356 4.9E-49 T 28-03-2018 IPR007498 Paraquat-inducible protein A AFA_RS07420 08185a94691628a14a3a2a346ecaace7 379 Gene3D G3DSA:1.20.1070.10 1 353 5.3E-5 T 28-03-2018 AFA_RS04040 7d1e53921c12b0c461a634d96b183440 409 SUPERFAMILY SSF103473 11 400 4.97E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS04040 7d1e53921c12b0c461a634d96b183440 409 Gene3D G3DSA:1.20.1250.20 211 404 8.6E-22 T 28-03-2018 AFA_RS04040 7d1e53921c12b0c461a634d96b183440 409 Pfam PF07690 Major Facilitator Superfamily 14 353 1.0E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS04040 7d1e53921c12b0c461a634d96b183440 409 Gene3D G3DSA:1.20.1250.20 1 200 5.1E-25 T 28-03-2018 AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 162 4.4E-54 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 SUPERFAMILY SSF50249 3 162 1.44E-56 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 PIRSF PIRSF002070 1 155 1.3E-37 T 28-03-2018 AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 Gene3D G3DSA:2.40.50.140 1 127 1.2E-44 T 28-03-2018 AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 Pfam PF00436 Single-strand binding protein family 4 108 3.5E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFA_RS12255 e5a49875a018d479a2168730c6e7d6c1 162 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 37.556 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 Gene3D G3DSA:3.40.50.720 50 247 7.2E-64 T 28-03-2018 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 Gene3D G3DSA:3.40.50.720 1 49 1.6E-12 T 28-03-2018 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 SUPERFAMILY SSF51735 8 247 1.89E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 5.5E-67 T 28-03-2018 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 11 245 2.7E-98 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS13110 c92098eb619d291ef5031dff6525e52b 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 1.1E-4 T 28-03-2018 AFA_RS01340 23066d6a665565d8267e3547c0257739 152 PIRSF PIRSF000714 3 142 1.4E-34 T 28-03-2018 IPR026026 Histidine triad hydrolase, Hint-type AFA_RS01340 23066d6a665565d8267e3547c0257739 152 Gene3D G3DSA:3.30.428.10 1 149 4.8E-25 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 AFA_RS01340 23066d6a665565d8267e3547c0257739 152 SUPERFAMILY SSF54197 2 114 1.86E-33 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 AFA_RS01340 23066d6a665565d8267e3547c0257739 152 Pfam PF01230 HIT domain 29 98 3.6E-13 T 28-03-2018 IPR001310 Histidine triad (HIT) protein AFA_RS15555 eb682bfb615eeddedc7eea12a47b316b 222 SUPERFAMILY SSF53474 13 221 2.59E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15555 eb682bfb615eeddedc7eea12a47b316b 222 Gene3D G3DSA:3.40.50.1820 9 222 7.4E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15555 eb682bfb615eeddedc7eea12a47b316b 222 Pfam PF02230 Phospholipase/Carboxylesterase 10 220 1.4E-53 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 AFA_RS18260 617ec62727daddaf59e6e9b941bc4e6c 98 Gene3D G3DSA:3.30.70.330 5 98 9.9E-31 T 28-03-2018 AFA_RS18260 617ec62727daddaf59e6e9b941bc4e6c 98 SUPERFAMILY SSF54189 2 91 6.47E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18260 617ec62727daddaf59e6e9b941bc4e6c 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 22.143 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFA_RS18260 617ec62727daddaf59e6e9b941bc4e6c 98 Pfam PF00276 Ribosomal protein L23 8 94 3.9E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFA_RS02355 7e90df308a1222d8f02af8bdc2bfec6f 391 Pfam PF01425 Amidase 30 379 1.8E-63 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS02355 7e90df308a1222d8f02af8bdc2bfec6f 391 Gene3D G3DSA:3.90.1300.10 8 390 3.2E-96 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS02355 7e90df308a1222d8f02af8bdc2bfec6f 391 SUPERFAMILY SSF75304 14 385 1.7E-94 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 Gene3D G3DSA:3.40.190.10 176 260 5.3E-19 T 28-03-2018 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 Gene3D G3DSA:1.10.10.10 5 89 5.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 Gene3D G3DSA:3.40.190.10 90 175 6.5E-5 T 28-03-2018 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 SUPERFAMILY SSF53850 93 289 1.16E-27 T 28-03-2018 AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 SUPERFAMILY SSF46785 6 85 6.62E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03290 8385177cc3f1a9a3e6d61d3522a8eadf 292 Pfam PF03466 LysR substrate binding domain 92 287 5.2E-24 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 Gene3D G3DSA:3.90.79.10 11 156 6.8E-31 T 28-03-2018 AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 PRINTS PR00502 NUDIX hydrolase family signature 40 54 1.6E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 PRINTS PR00502 NUDIX hydrolase family signature 54 69 1.6E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 Pfam PF00293 NUDIX domain 18 132 5.4E-22 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS08045 f2c6b980d8136f9cb13b468960ca06ab 157 SUPERFAMILY SSF55811 9 140 1.18E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS15225 433be36da466a422ace32ae140996b88 600 Gene3D G3DSA:1.10.287.130 359 438 6.2E-11 T 28-03-2018 AFA_RS15225 433be36da466a422ace32ae140996b88 600 Gene3D G3DSA:3.30.450.20 161 286 4.0E-6 T 28-03-2018 AFA_RS15225 433be36da466a422ace32ae140996b88 600 Gene3D G3DSA:3.30.450.20 50 160 5.7E-18 T 28-03-2018 AFA_RS15225 433be36da466a422ace32ae140996b88 600 SUPERFAMILY SSF103190 82 184 1.1E-12 T 28-03-2018 IPR029151 Periplasmic sensor domain-like AFA_RS15225 433be36da466a422ace32ae140996b88 600 Pfam PF00512 His Kinase A (phospho-acceptor) domain 375 439 3.8E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15225 433be36da466a422ace32ae140996b88 600 Gene3D G3DSA:3.30.565.10 442 599 1.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15225 433be36da466a422ace32ae140996b88 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 537 6.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15225 433be36da466a422ace32ae140996b88 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 6.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15225 433be36da466a422ace32ae140996b88 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 551 6.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS15225 433be36da466a422ace32ae140996b88 600 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 589 8.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15225 433be36da466a422ace32ae140996b88 600 SMART SM00387 484 592 2.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15225 433be36da466a422ace32ae140996b88 600 SUPERFAMILY SSF47384 363 440 9.61E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15225 433be36da466a422ace32ae140996b88 600 SUPERFAMILY SSF55874 446 588 5.11E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS15225 433be36da466a422ace32ae140996b88 600 Pfam PF02743 Cache domain 28 271 7.4E-12 T 28-03-2018 IPR033479 Double Cache domain 1 AFA_RS15225 433be36da466a422ace32ae140996b88 600 SMART SM00388 374 442 2.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS15225 433be36da466a422ace32ae140996b88 600 PIRSF PIRSF036431 1 598 1.9E-162 T 28-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 SUPERFAMILY SSF46785 2 93 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 Pfam PF12840 Helix-turn-helix domain 9 69 6.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 Gene3D G3DSA:1.10.10.10 1 83 3.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 SMART SM00418 8 89 2.5E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.9E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.9E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS07915 224905c7d0de04b24e8128c6204e6efe 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.9E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 Gene3D G3DSA:3.40.50.300 1 290 3.1E-129 T 28-03-2018 AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 Gene3D G3DSA:3.40.50.880 291 547 2.8E-72 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 SUPERFAMILY SSF52540 3 271 7.97E-120 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 Pfam PF06418 CTP synthase N-terminus 4 271 3.6E-124 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 Pfam PF00117 Glutamine amidotransferase class-I 306 539 2.0E-53 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 TIGRFAM TIGR00337 PyrG: CTP synthase 2 539 2.6E-236 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 SUPERFAMILY SSF52317 293 546 5.59E-85 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS12915 4422a499edc9f1a9b1df54dc758a812f 548 Hamap MF_01227 CTP synthase [pyrG]. 3 544 50.296 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 Gene3D G3DSA:3.30.70.980 83 176 4.6E-27 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 Gene3D G3DSA:3.30.70.980 179 238 1.3E-7 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 Pfam PF01709 Transcriptional regulator 5 236 8.2E-90 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 9.5E-88 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 SUPERFAMILY SSF75625 3 241 2.22E-90 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 33.596 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS12700 21bc1c9b2b03d89b78e8419d66331832 243 Gene3D G3DSA:1.10.10.200 1 78 3.0E-32 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like AFA_RS04865 10ed28e80b18fc75bf04b0c3a65514d6 86 Pfam PF03937 Flavinator of succinate dehydrogenase 9 77 2.5E-19 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase AFA_RS04865 10ed28e80b18fc75bf04b0c3a65514d6 86 SUPERFAMILY SSF109910 3 81 3.01E-18 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase AFA_RS04865 10ed28e80b18fc75bf04b0c3a65514d6 86 Gene3D G3DSA:1.10.150.250 3 86 2.0E-20 T 28-03-2018 AFA_RS06650 5914822633c01b9e0fa170387e6069aa 156 Pfam PF00583 Acetyltransferase (GNAT) family 37 105 9.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS06650 5914822633c01b9e0fa170387e6069aa 156 SUPERFAMILY SSF55729 20 154 2.03E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS06650 5914822633c01b9e0fa170387e6069aa 156 Gene3D G3DSA:3.40.630.30 6 155 3.3E-25 T 28-03-2018 AFA_RS08420 b26111d6a79694ed94a002cd7d9ebe28 206 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 5 204 3.9E-64 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 AFA_RS08420 b26111d6a79694ed94a002cd7d9ebe28 206 Pfam PF03006 Haemolysin-III related 2 197 7.4E-43 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Gene3D G3DSA:1.10.150.130 3 112 1.4E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 298 56.087 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 298 9.7E-110 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Pfam PF00589 Phage integrase family 112 283 8.6E-52 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Gene3D G3DSA:1.10.443.10 113 292 1.4E-49 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 90 1.1E-20 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 3 298 56.429 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFA_RS04050 e0ebe3a54065c0b55cdb8bbe628841dd 298 SUPERFAMILY SSF56349 1 288 4.41E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS04730 b51ec22a38d8fcdd16ba71330150b9ac 325 SUPERFAMILY SSF161098 108 306 3.4E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04730 b51ec22a38d8fcdd16ba71330150b9ac 325 Gene3D G3DSA:1.10.3720.10 3 312 2.5E-29 T 28-03-2018 AFA_RS04730 b51ec22a38d8fcdd16ba71330150b9ac 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 323 6.1E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14040 c7ce3eb37e7cf6daf2f84b3a3b753b07 584 SUPERFAMILY SSF53474 216 505 6.73E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14040 c7ce3eb37e7cf6daf2f84b3a3b753b07 584 Gene3D G3DSA:3.40.50.1820 203 512 5.3E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14040 c7ce3eb37e7cf6daf2f84b3a3b753b07 584 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 9 50 4.3E-13 T 28-03-2018 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal AFA_RS14040 c7ce3eb37e7cf6daf2f84b3a3b753b07 584 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 93 262 4.0E-57 T 28-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 ProSitePatterns PS01348 MraY family signature 2. 213 224 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 26 388 23.507 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 ProSitePatterns PS01347 MraY family signature 1. 69 81 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 69 81 2.7E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 Pfam PF00953 Glycosyl transferase family 4 100 308 3.9E-35 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 AFA_RS03650 e071a4ae54d42a390cf71f04bcfba9ca 390 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 390 3.1E-123 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 SUPERFAMILY SSF46785 85 159 1.74E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 Gene3D G3DSA:1.10.10.10 84 175 1.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 SUPERFAMILY SSF46785 5 80 1.22E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 167 5.0E-46 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 Gene3D G3DSA:1.10.10.10 1 83 9.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS05080 ef1fa76b0809d0fbc4b74387ad58605f 329 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 21 176 4.2E-29 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 238 1.8E-42 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 612 7.1E-223 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 SUPERFAMILY SSF56519 54 252 4.45E-47 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 SUPERFAMILY SSF56601 253 612 7.63E-98 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 Gene3D G3DSA:3.90.1310.10 31 248 6.0E-51 T 28-03-2018 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 Pfam PF00905 Penicillin binding protein transpeptidase domain 270 608 3.8E-69 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFA_RS15860 4302fc73d1eba7f17e1ec4f772635b58 619 Gene3D G3DSA:3.40.710.10 249 618 2.6E-91 T 28-03-2018 AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 Gene3D G3DSA:1.10.10.10 722 776 2.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 Pfam PF09397 Ftsk gamma domain 722 782 5.2E-26 T 28-03-2018 IPR018541 FtsK gamma domain AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 Pfam PF01580 FtsK/SpoIIIE family 405 614 6.0E-67 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 SUPERFAMILY SSF46785 721 785 1.12E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 SMART SM00382 440 635 7.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 SUPERFAMILY SSF52540 395 686 7.44E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 32 214 1.9E-37 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 SMART SM00843 720 785 4.2E-37 T 28-03-2018 IPR018541 FtsK gamma domain AFA_RS13545 5c55e7e2cd02daf05bffefab835b90b8 791 Gene3D G3DSA:3.40.50.300 231 653 8.8E-58 T 28-03-2018 AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 Gene3D G3DSA:2.60.120.10 275 398 1.6E-49 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 Gene3D G3DSA:2.60.120.10 196 271 3.9E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 Pfam PF04209 homogentisate 1,2-dioxygenase 5 428 1.1E-195 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 5 430 68.705 T 28-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 4 428 2.1E-194 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 AFA_RS02765 c9778dd744b4a4145d122b261a90dacb 434 SUPERFAMILY SSF51182 4 432 2.13E-165 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS13130 1af9c308d8cf402671943f011bee4b54 60 Pfam PF01783 Ribosomal L32p protein family 2 55 6.2E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS13130 1af9c308d8cf402671943f011bee4b54 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.146 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS13130 1af9c308d8cf402671943f011bee4b54 60 SUPERFAMILY SSF57829 2 55 3.97E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFA_RS13130 1af9c308d8cf402671943f011bee4b54 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.9E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS10420 c439807f0df07198daf5d0f0b68d6ee8 322 Pfam PF04392 ABC transporter substrate binding protein 30 320 2.1E-106 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein AFA_RS10420 c439807f0df07198daf5d0f0b68d6ee8 322 Gene3D G3DSA:3.40.50.2300 29 151 2.1E-20 T 28-03-2018 AFA_RS10420 c439807f0df07198daf5d0f0b68d6ee8 322 SUPERFAMILY SSF53822 34 283 1.51E-19 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS10420 c439807f0df07198daf5d0f0b68d6ee8 322 Gene3D G3DSA:3.40.50.2300 152 286 9.1E-20 T 28-03-2018 AFA_RS17715 770796a90c3f86d0ea4610e16f84fcf8 343 Gene3D G3DSA:3.20.20.30 10 333 7.6E-56 T 28-03-2018 AFA_RS17715 770796a90c3f86d0ea4610e16f84fcf8 343 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS17715 770796a90c3f86d0ea4610e16f84fcf8 343 Pfam PF00296 Luciferase-like monooxygenase 32 247 3.5E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS17715 770796a90c3f86d0ea4610e16f84fcf8 343 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 21 330 8.3E-118 T 28-03-2018 IPR020020 Luciferase-type oxidoreductase AFA_RS17715 770796a90c3f86d0ea4610e16f84fcf8 343 SUPERFAMILY SSF51679 29 331 4.19E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 Gene3D G3DSA:1.10.3720.10 18 194 1.5E-18 T 28-03-2018 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 SUPERFAMILY SSF161098 190 376 3.14E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 390 3.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 SUPERFAMILY SSF161098 88 155 9.55E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 87 151 3.9E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS15830 173da8addfb4ee776d4187feb849d237 395 Gene3D G3DSA:1.10.3720.10 195 395 4.9E-37 T 28-03-2018 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 Gene3D G3DSA:1.10.10.60 227 277 3.7E-11 T 28-03-2018 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 SUPERFAMILY SSF51215 32 159 6.15E-7 T 28-03-2018 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 SMART SM00342 191 274 2.5E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 SUPERFAMILY SSF46689 233 276 3.0E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 Gene3D G3DSA:2.60.120.280 18 151 8.9E-6 T 28-03-2018 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 Pfam PF12833 Helix-turn-helix domain 197 275 2.7E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17685 61091cb06712b4c22aa403439a2a9d1b 287 Gene3D G3DSA:1.10.10.60 152 226 0.015 T 28-03-2018 AFA_RS14160 83c2d6cb0a869930c47235692ed27aed 202 Gene3D G3DSA:1.10.760.10 28 193 8.6E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14160 83c2d6cb0a869930c47235692ed27aed 202 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 3 146 5.6E-32 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AFA_RS14160 83c2d6cb0a869930c47235692ed27aed 202 SUPERFAMILY SSF46626 90 187 8.99E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14160 83c2d6cb0a869930c47235692ed27aed 202 SUPERFAMILY SSF46626 12 63 8.99E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 8.1E-90 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 Gene3D G3DSA:3.40.47.10 266 390 4.1E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 PIRSF PIRSF000429 1 393 4.5E-115 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 SUPERFAMILY SSF53901 5 269 1.4E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 9.2E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 SUPERFAMILY SSF53901 271 392 1.12E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 7.0E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS00680 811d113124b914f0cea28433aaeae635 393 Gene3D G3DSA:3.40.47.10 2 265 1.1E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS16335 3b2dd3c09a180507dd33cf80ccc3c574 206 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 182 4.7E-36 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 AFA_RS16335 3b2dd3c09a180507dd33cf80ccc3c574 206 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 12 181 3.9E-32 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related AFA_RS16335 3b2dd3c09a180507dd33cf80ccc3c574 206 Gene3D G3DSA:2.60.450.10 52 195 6.7E-4 T 28-03-2018 AFA_RS06345 59c36e4e70ccb6d4a8e618724aa2e2d3 334 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 108 315 4.9E-91 T 28-03-2018 IPR014142 P-type conjugative transfer protein TrbG AFA_RS06345 59c36e4e70ccb6d4a8e618724aa2e2d3 334 Pfam PF03524 Conjugal transfer protein 107 327 1.6E-64 T 28-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX AFA_RS09640 71832dd6fd016769cde15fbbed338913 542 Pfam PF07916 TraG-like protein, N-terminal region 8 525 2.7E-49 T 28-03-2018 IPR012931 TraG-like, N-terminal AFA_RS06110 c881fd34bc210b1ef8ac0656beee480e 467 Pfam PF02447 GntP family permease 6 316 1.5E-8 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFA_RS05405 c193496f540709e1a9b908174005e729 254 Gene3D G3DSA:3.40.50.620 70 217 4.0E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS05405 c193496f540709e1a9b908174005e729 254 Pfam PF02698 DUF218 domain 79 244 1.9E-32 T 28-03-2018 IPR003848 Domain of unknown function DUF218 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 2.0E-30 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 SUPERFAMILY SSF111148 1 89 1.57E-36 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 2.2E-39 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 PIRSF PIRSF029827 1 90 7.9E-39 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 26.804 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS05350 885169a2d16e3aca80586b745d2c36fa 90 Gene3D G3DSA:1.10.3880.10 2 89 1.1E-37 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFA_RS15870 11f5b6ea214af34a21e52632253df218 293 PIRSF PIRSF038471 8 289 1.5E-61 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFA_RS15870 11f5b6ea214af34a21e52632253df218 293 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 275 1.1E-43 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFA_RS15870 11f5b6ea214af34a21e52632253df218 293 Pfam PF04085 rod shape-determining protein MreC 128 274 2.7E-34 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFA_RS13355 cbedb7600ea9c4fb1abf0ee0a2701436 492 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 479 18.028 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFA_RS13355 cbedb7600ea9c4fb1abf0ee0a2701436 492 Pfam PF00361 Proton-conducting membrane transporter 127 427 2.8E-73 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13355 cbedb7600ea9c4fb1abf0ee0a2701436 492 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 476 5.0E-137 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFA_RS04105 c8df0e145e2c86ccb2add740d333c755 346 Pfam PF13379 NMT1-like family 36 271 3.0E-30 T 28-03-2018 AFA_RS04105 c8df0e145e2c86ccb2add740d333c755 346 Gene3D G3DSA:3.40.190.10 30 137 3.1E-12 T 28-03-2018 AFA_RS04105 c8df0e145e2c86ccb2add740d333c755 346 Gene3D G3DSA:3.40.190.10 138 340 1.5E-30 T 28-03-2018 AFA_RS04105 c8df0e145e2c86ccb2add740d333c755 346 SUPERFAMILY SSF53850 32 277 6.04E-45 T 28-03-2018 AFA_RS10675 aab03acb260044b4d02805374a9b8cdd 482 Gene3D G3DSA:3.40.50.720 65 436 2.0E-33 T 28-03-2018 AFA_RS10675 aab03acb260044b4d02805374a9b8cdd 482 Pfam PF01266 FAD dependent oxidoreductase 69 429 1.8E-44 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS10675 aab03acb260044b4d02805374a9b8cdd 482 SUPERFAMILY SSF51905 68 295 1.46E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10675 aab03acb260044b4d02805374a9b8cdd 482 SUPERFAMILY SSF51905 390 463 1.46E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00100 b0306bef2b368d3b701560fc36ace061 355 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 315 1.8E-57 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS00100 b0306bef2b368d3b701560fc36ace061 355 PIRSF PIRSF039026 1 352 5.7E-111 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 Gene3D G3DSA:3.40.1060.10 156 290 1.4E-39 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 Gene3D G3DSA:3.30.499.10 294 470 2.1E-52 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 2.9E-153 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 466 3.6E-216 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 110 118 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 344 355 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 135 150 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 401 414 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 197 210 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 211 224 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 121 134 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 84 97 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 PRINTS PR00415 Aconitase family signature 288 302 8.5E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 468 56.527 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 Gene3D G3DSA:3.30.499.10 2 155 7.8E-36 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00775 4897e4fd48019e3a6aeee11b33546b21 470 SUPERFAMILY SSF53732 5 469 3.4E-156 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS09120 a49d24c455e41626ae67da68bea308e1 430 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 6 422 9.1E-153 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS09120 a49d24c455e41626ae67da68bea308e1 430 Pfam PF00296 Luciferase-like monooxygenase 17 380 6.6E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS09120 a49d24c455e41626ae67da68bea308e1 430 Gene3D G3DSA:3.20.20.30 1 430 6.0E-97 T 28-03-2018 AFA_RS09120 a49d24c455e41626ae67da68bea308e1 430 SUPERFAMILY SSF51679 2 428 4.71E-119 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS09120 a49d24c455e41626ae67da68bea308e1 430 PIRSF PIRSF000337 1 430 6.1E-146 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 AFA_RS01810 910597965922107ac972311e35cfe06b 682 SUPERFAMILY SSF56935 35 265 1.34E-94 T 28-03-2018 AFA_RS01810 910597965922107ac972311e35cfe06b 682 SUPERFAMILY SSF56935 298 682 1.34E-94 T 28-03-2018 AFA_RS01810 910597965922107ac972311e35cfe06b 682 Gene3D G3DSA:2.40.170.20 161 682 4.1E-60 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS01810 910597965922107ac972311e35cfe06b 682 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 151 6.5E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS01810 910597965922107ac972311e35cfe06b 682 Gene3D G3DSA:2.170.130.10 23 158 1.1E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS01810 910597965922107ac972311e35cfe06b 682 Pfam PF00593 TonB dependent receptor 219 680 9.4E-45 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS15065 74cc30330dc85aaa5ba83b52c1a038a3 340 Pfam PF13478 XdhC Rossmann domain 171 313 5.6E-36 T 28-03-2018 IPR027051 XdhC Rossmann domain AFA_RS15065 74cc30330dc85aaa5ba83b52c1a038a3 340 Gene3D G3DSA:3.40.50.720 167 330 4.0E-6 T 28-03-2018 AFA_RS15065 74cc30330dc85aaa5ba83b52c1a038a3 340 Pfam PF02625 XdhC and CoxI family 15 89 1.0E-19 T 28-03-2018 IPR003777 XdhC- CoxI AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 Gene3D G3DSA:3.40.710.10 264 749 1.8E-113 T 28-03-2018 AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 Pfam PF00912 Transglycosylase 76 249 1.8E-60 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 Pfam PF00905 Penicillin binding protein transpeptidase domain 451 697 1.2E-38 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 SUPERFAMILY SSF53955 62 271 5.62E-74 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 85 735 4.5E-178 T 28-03-2018 AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 Pfam PF17092 Penicillin-binding protein OB-like domain 340 448 5.7E-13 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 Gene3D G3DSA:1.10.3810.10 68 263 1.8E-75 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 SUPERFAMILY SSF56601 231 253 2.33E-117 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 SUPERFAMILY SSF56601 286 337 2.33E-117 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS17895 10e9b4be013adcf93a4f1ec74e8bcea4 815 SUPERFAMILY SSF56601 445 763 2.33E-117 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PIRSF PIRSF000097 111 269 2.2E-19 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PIRSF PIRSF000097 2 115 3.2E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PRINTS PR00069 Aldo-keto reductase signature 123 140 1.1E-16 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.1E-16 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PRINTS PR00069 Aldo-keto reductase signature 202 226 1.1E-16 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.1E-16 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 Gene3D G3DSA:3.20.20.100 2 276 9.3E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 SUPERFAMILY SSF51430 3 270 1.57E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS10535 f2bf725e1590d30209f3a7876aadc030 280 Pfam PF00248 Aldo/keto reductase family 17 266 2.0E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 SUPERFAMILY SSF51726 5 400 4.32E-107 T 28-03-2018 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 PIRSF PIRSF000382 1 764 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 437 758 6.2E-153 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 Gene3D G3DSA:3.20.20.210 396 763 1.1E-126 T 28-03-2018 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 319 3.1E-119 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 762 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 763 36.999 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 Gene3D G3DSA:3.20.20.210 2 395 1.4E-143 T 28-03-2018 AFA_RS10990 50a3e695406b61349cd9acfca0f8f19b 764 SUPERFAMILY SSF51726 411 761 1.31E-118 T 28-03-2018 AFA_RS02635 4c80603475d5bb1d533a211d53abb7a3 222 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 62 221 1.8E-42 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AFA_RS02635 4c80603475d5bb1d533a211d53abb7a3 222 SUPERFAMILY SSF47240 58 136 2.95E-18 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS02635 4c80603475d5bb1d533a211d53abb7a3 222 Gene3D G3DSA:1.20.1260.10 52 197 1.6E-22 T 28-03-2018 IPR012347 Ferritin-related AFA_RS02635 4c80603475d5bb1d533a211d53abb7a3 222 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 23 222 30.149 T 28-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 1.6E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 SUPERFAMILY SSF88659 88 159 1.16E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 Pfam PF04542 Sigma-70 region 2 10 77 5.6E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 Gene3D G3DSA:1.10.1740.10 2 76 1.0E-15 T 28-03-2018 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 SUPERFAMILY SSF88946 5 97 7.85E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 Pfam PF08281 Sigma-70, region 4 109 158 3.9E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS17475 05b5bfbdee1fe88a450e8686ab5d29af 179 Gene3D G3DSA:1.10.10.10 77 161 3.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16990 88a7d755a89a59b9cbc0a6c017f74968 253 Gene3D G3DSA:3.90.550.10 18 203 5.6E-7 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16990 88a7d755a89a59b9cbc0a6c017f74968 253 SUPERFAMILY SSF53448 22 148 1.13E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS18490 bf70aa159586f49ab87f7b44890b0f5b 345 Pfam PF13310 Virulence protein RhuM family 70 323 1.2E-113 T 28-03-2018 IPR011204 Virulence protein RhuM-like AFA_RS18490 bf70aa159586f49ab87f7b44890b0f5b 345 Gene3D G3DSA:1.10.10.10 13 91 0.049 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18490 bf70aa159586f49ab87f7b44890b0f5b 345 PIRSF PIRSF015268 4 345 2.7E-145 T 28-03-2018 IPR011204 Virulence protein RhuM-like AFA_RS01235 d3daaabbce0c09b2fc3ed8abc15acd89 90 Pfam PF04359 Protein of unknown function (DUF493) 7 90 5.6E-29 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 AFA_RS01235 d3daaabbce0c09b2fc3ed8abc15acd89 90 Gene3D G3DSA:3.30.70.260 6 90 2.3E-29 T 28-03-2018 AFA_RS01235 d3daaabbce0c09b2fc3ed8abc15acd89 90 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 2 90 21.445 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 AFA_RS01235 d3daaabbce0c09b2fc3ed8abc15acd89 90 SUPERFAMILY SSF117991 6 90 2.49E-25 T 28-03-2018 IPR027471 YbeD-like domain AFA_RS00695 92ed74b3829b59b9f736dc811d6de7d7 130 Gene3D G3DSA:1.10.1660.10 1 58 3.5E-19 T 28-03-2018 AFA_RS00695 92ed74b3829b59b9f736dc811d6de7d7 130 SMART SM00422 6 73 3.0E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS00695 92ed74b3829b59b9f736dc811d6de7d7 130 Gene3D G3DSA:1.10.1660.10 59 129 4.9E-11 T 28-03-2018 AFA_RS00695 92ed74b3829b59b9f736dc811d6de7d7 130 SUPERFAMILY SSF46955 6 121 7.33E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS00695 92ed74b3829b59b9f736dc811d6de7d7 130 Pfam PF13411 MerR HTH family regulatory protein 7 71 1.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 Gene3D G3DSA:2.40.50.140 8 81 3.7E-29 T 28-03-2018 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 PIRSF PIRSF002599 11 81 1.1E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 SUPERFAMILY SSF50249 15 79 1.5E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 PRINTS PR00050 Cold shock protein signature 54 72 3.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 PRINTS PR00050 Cold shock protein signature 39 48 3.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 PRINTS PR00050 Cold shock protein signature 18 33 3.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 SMART SM00357 17 81 1.5E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 Pfam PF00313 'Cold-shock' DNA-binding domain 17 80 7.9E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS07405 e0226ca6228786cfd69c22c608b70d2d 81 ProSitePatterns PS00352 'Cold-shock' domain signature. 29 48 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS09655 da754ec921ae574613a1aa495d3730e6 208 SUPERFAMILY SSF56349 22 206 5.0E-35 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS09655 da754ec921ae574613a1aa495d3730e6 208 Gene3D G3DSA:1.10.443.10 21 198 1.6E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS09655 da754ec921ae574613a1aa495d3730e6 208 Pfam PF00589 Phage integrase family 41 192 1.1E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS14950 06b3db788b039348f616d8df76e49600 216 Gene3D G3DSA:3.40.50.850 4 215 3.7E-47 T 28-03-2018 AFA_RS14950 06b3db788b039348f616d8df76e49600 216 Pfam PF00857 Isochorismatase family 34 209 6.3E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS14950 06b3db788b039348f616d8df76e49600 216 SUPERFAMILY SSF52499 26 212 7.98E-54 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS06500 27542786b5b754fa82de995bf5fb1267 176 Pfam PF02464 Competence-damaged protein 8 160 1.7E-38 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS06500 27542786b5b754fa82de995bf5fb1267 176 Gene3D G3DSA:3.90.950.20 2 167 5.2E-42 T 28-03-2018 AFA_RS06500 27542786b5b754fa82de995bf5fb1267 176 SUPERFAMILY SSF142433 7 162 1.44E-39 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS06500 27542786b5b754fa82de995bf5fb1267 176 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 158 1.7E-26 T 28-03-2018 IPR008136 CinA, C-terminal AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.794 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 SUPERFAMILY SSF55811 4 161 2.44E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 Gene3D G3DSA:3.90.79.10 1 164 3.6E-32 T 28-03-2018 AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 Pfam PF00293 NUDIX domain 7 138 9.7E-23 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFA_RS14600 51566b361dd60c6d2688ab0c3cb91490 188 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 PIRSF PIRSF000447 1 410 3.2E-181 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 SMART SM00825 Beta-ketoacyl synthase 5 410 1.8E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFA_RS13100 445a1af11f61038b0091730d147d6068 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site AFA_RS13100 445a1af11f61038b0091730d147d6068 410 Gene3D G3DSA:3.40.47.10 1 258 1.4E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 366 4.1E-31 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFA_RS13100 445a1af11f61038b0091730d147d6068 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 4.3E-63 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFA_RS13100 445a1af11f61038b0091730d147d6068 410 Gene3D G3DSA:3.40.47.10 259 409 5.4E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 407 7.2E-195 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 SUPERFAMILY SSF53901 213 408 2.08E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS13100 445a1af11f61038b0091730d147d6068 410 SUPERFAMILY SSF53901 2 251 1.79E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.4E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.4E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.4E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 SUPERFAMILY SSF54570 2 84 3.53E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 6.3E-46 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 Gene3D G3DSA:3.30.860.10 1 91 4.7E-40 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 Pfam PF00203 Ribosomal protein S19 3 83 2.6E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 PIRSF PIRSF002144 1 91 1.1E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18250 698360ee0dd4853be0cb65a1c409662c 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.746 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 SUPERFAMILY SSF47203 231 396 3.7E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 PIRSF PIRSF016578 2 393 1.1E-35 T 28-03-2018 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Gene3D G3DSA:1.20.140.10 223 398 3.9E-23 T 28-03-2018 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 241 374 2.3E-18 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 215 1.8E-8 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 SUPERFAMILY SSF56645 21 223 9.16E-45 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Gene3D G3DSA:2.40.110.10 124 222 5.0E-15 T 28-03-2018 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 10 398 5.0E-179 T 28-03-2018 IPR023922 Sulphate-starvation-induced SfnB AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Gene3D G3DSA:1.10.540.10 3 123 1.0E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS00500 c0b9f56869585a89edb95300abca9185 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 121 3.6E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 SUPERFAMILY SSF54593 193 310 1.41E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 SUPERFAMILY SSF54593 14 173 8.94E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 Gene3D G3DSA:3.10.180.10 253 328 6.4E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 Gene3D G3DSA:3.10.180.10 89 252 5.0E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 Gene3D G3DSA:3.10.180.10 2 77 1.0E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 201 307 4.8E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS09250 08127d8e12319aaaed5158c07bf7e5b3 330 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 146 1.5E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 SMART SM00644 38 176 2.4E-32 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 Gene3D G3DSA:1.10.101.10 194 269 1.6E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 SUPERFAMILY SSF47090 205 268 3.92E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 Pfam PF01471 Putative peptidoglycan binding domain 216 265 6.2E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 Gene3D G3DSA:3.40.80.10 37 193 1.4E-43 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 SUPERFAMILY SSF55846 39 192 6.28E-49 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS13150 84615e6f834b57c1bd9f3f920fadaae1 269 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 47 177 1.0E-28 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFA_RS06660 562aec6bd46a79ca0d5329cbb5ce6a1e 252 Pfam PF01435 Peptidase family M48 71 247 9.3E-29 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFA_RS06660 562aec6bd46a79ca0d5329cbb5ce6a1e 252 Gene3D G3DSA:3.30.2010.10 61 150 1.0E-22 T 28-03-2018 AFA_RS07095 c58afa6c9450de32b12990d41f57bbbe 247 Pfam PF05100 Phage minor tail protein L 25 224 1.2E-69 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail AFA_RS07095 c58afa6c9450de32b12990d41f57bbbe 247 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 245 1.8E-79 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 751 937 6.5E-20 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 SUPERFAMILY SSF53323 742 943 8.24E-28 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 SUPERFAMILY SSF52518 28 241 3.18E-20 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Gene3D G3DSA:3.40.50.970 25 287 1.8E-22 T 28-03-2018 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 477 562 8.0E-7 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 SUPERFAMILY SSF52518 457 643 2.09E-16 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Gene3D G3DSA:3.40.50.920 288 431 1.7E-6 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Gene3D G3DSA:3.40.920.10 741 947 1.4E-43 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFA_RS04280 97a5d172b597072c467b1d909d858013 1185 Gene3D G3DSA:3.40.50.970 461 645 3.1E-31 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 SUPERFAMILY SSF51905 284 395 1.62E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 SUPERFAMILY SSF51905 24 193 1.62E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 Gene3D G3DSA:3.30.9.10 179 300 3.8E-24 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 Gene3D G3DSA:3.30.9.10 301 385 2.2E-17 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 Gene3D G3DSA:3.50.50.60 3 178 9.6E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 24 46 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 330 348 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 348 364 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 2.6E-34 T 28-03-2018 AFA_RS02775 b21934b3980df6334db51105dcfaef9c 557 Pfam PF01494 FAD binding domain 24 361 9.0E-62 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS05370 1d6c9492759dc5c8b6f624a294e6e143 368 Pfam PF00534 Glycosyl transferases group 1 175 338 5.9E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS05370 1d6c9492759dc5c8b6f624a294e6e143 368 Pfam PF13439 Glycosyltransferase Family 4 15 164 1.3E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS05370 1d6c9492759dc5c8b6f624a294e6e143 368 SUPERFAMILY SSF53756 6 359 5.24E-72 T 28-03-2018 AFA_RS05370 1d6c9492759dc5c8b6f624a294e6e143 368 Gene3D G3DSA:3.40.50.2000 176 346 1.6E-41 T 28-03-2018 AFA_RS05370 1d6c9492759dc5c8b6f624a294e6e143 368 Gene3D G3DSA:3.40.50.2000 1 175 2.2E-22 T 28-03-2018 AFA_RS00265 a82fa91334cd645bd0dc8e9b0ed31e2a 147 SUPERFAMILY SSF54637 4 138 8.38E-33 T 28-03-2018 IPR029069 HotDog domain AFA_RS00265 a82fa91334cd645bd0dc8e9b0ed31e2a 147 Pfam PF03061 Thioesterase superfamily 21 96 1.4E-6 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS00265 a82fa91334cd645bd0dc8e9b0ed31e2a 147 Gene3D G3DSA:3.10.129.10 1 141 7.1E-23 T 28-03-2018 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 SUPERFAMILY SSF53649 14 119 1.89E-110 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 SUPERFAMILY SSF53649 161 500 1.89E-110 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 Gene3D G3DSA:3.30.1120.10 440 521 3.3E-13 T 28-03-2018 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 Gene3D G3DSA:3.40.720.10 12 423 2.5E-81 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 Pfam PF16347 Domain of unknown function (DUF4976) 399 498 5.9E-7 T 28-03-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096 AFA_RS00235 c2ed5d335347f3f27a6a3abba9277939 531 Pfam PF00884 Sulfatase 14 392 2.9E-54 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 SUPERFAMILY SSF52833 4 210 7.24E-70 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 189 3.3E-10 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 PIRSF PIRSF000239 1 210 1.1E-78 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 Gene3D G3DSA:3.30.1020.10 153 213 2.7E-24 T 28-03-2018 AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 Gene3D G3DSA:3.40.30.10 1 152 2.9E-41 T 28-03-2018 AFA_RS11895 bc1482ac2ee77c1df77345a425a59b86 213 Pfam PF00578 AhpC/TSA family 7 136 6.9E-33 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFA_RS09830 35ec1f6de28cc5c71326868a2b46c0d4 145 SUPERFAMILY SSF50249 1 132 5.48E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS09830 35ec1f6de28cc5c71326868a2b46c0d4 145 Gene3D G3DSA:2.40.50.140 1 119 5.9E-15 T 28-03-2018 AFA_RS09830 35ec1f6de28cc5c71326868a2b46c0d4 145 PIRSF PIRSF002070 1 144 3.7E-12 T 28-03-2018 AFA_RS09830 35ec1f6de28cc5c71326868a2b46c0d4 145 Pfam PF00436 Single-strand binding protein family 8 112 1.7E-6 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 SUPERFAMILY SSF46785 1 70 3.54E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 Pfam PF01614 Bacterial transcriptional regulator 123 241 4.0E-13 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 Pfam PF09339 IclR helix-turn-helix domain 3 50 1.5E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 Gene3D G3DSA:1.10.10.10 1 62 1.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 SUPERFAMILY SSF55781 57 243 6.08E-29 T 28-03-2018 IPR029016 GAF domain-like AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 Gene3D G3DSA:3.30.450.40 74 246 8.2E-32 T 28-03-2018 IPR029016 GAF domain-like AFA_RS00230 ac17f00d4f76acd7bb75fe2e1ba5ac96 246 SMART SM00346 1 89 6.4E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFA_RS02865 e61ddd5b95fc3f42097b119b5574d569 213 Gene3D G3DSA:3.40.30.10 8 212 5.6E-27 T 28-03-2018 AFA_RS02865 e61ddd5b95fc3f42097b119b5574d569 213 Pfam PF13743 Thioredoxin 19 187 2.3E-11 T 28-03-2018 AFA_RS02865 e61ddd5b95fc3f42097b119b5574d569 213 SUPERFAMILY SSF52833 10 212 4.48E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 5 416 2.8E-198 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 Gene3D G3DSA:3.90.1150.10 304 419 4.3E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 Pfam PF00202 Aminotransferase class-III 20 413 3.6E-80 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 PIRSF PIRSF000521 178 418 2.5E-32 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 PIRSF PIRSF000521 4 160 1.9E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 Gene3D G3DSA:3.40.640.10 178 303 1.5E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 Gene3D G3DSA:3.90.1150.10 2 166 6.3E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 SUPERFAMILY SSF53383 9 415 5.55E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS12625 d3c1ddab058f3ec319e13f3800f3c3ad 435 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 3 420 7.1E-144 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 AFA_RS16170 f3a443cb71f17a055ec59e9c54991926 268 SUPERFAMILY SSF110399 8 249 6.15E-87 T 28-03-2018 AFA_RS16170 f3a443cb71f17a055ec59e9c54991926 268 Pfam PF05690 Thiazole biosynthesis protein ThiG 12 259 2.2E-105 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFA_RS16170 f3a443cb71f17a055ec59e9c54991926 268 Hamap MF_00443 Thiazole synthase [thiG]. 9 265 41.711 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFA_RS16170 f3a443cb71f17a055ec59e9c54991926 268 Gene3D G3DSA:3.20.20.70 7 268 2.0E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS17165 13bdf6dc91b4e252f4f8def4e177b4b1 134 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 9.0E-20 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS17165 13bdf6dc91b4e252f4f8def4e177b4b1 134 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 5.6E-35 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS17165 13bdf6dc91b4e252f4f8def4e177b4b1 134 SUPERFAMILY SSF141734 7 114 4.18E-48 T 28-03-2018 AFA_RS17165 13bdf6dc91b4e252f4f8def4e177b4b1 134 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 33.225 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFA_RS17995 b1dca13ee173db95628d355f040b55d2 72 Gene3D G3DSA:2.40.50.140 1 72 1.8E-34 T 28-03-2018 AFA_RS17995 b1dca13ee173db95628d355f040b55d2 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.742 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFA_RS17995 b1dca13ee173db95628d355f040b55d2 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.2E-36 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFA_RS17995 b1dca13ee173db95628d355f040b55d2 72 SUPERFAMILY SSF50249 1 70 7.43E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS17995 b1dca13ee173db95628d355f040b55d2 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.8E-26 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 138 3.5E-10 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 SMART SM01008 29 138 1.4E-21 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Gene3D G3DSA:3.30.365.10 169 276 9.0E-27 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 718 1.9E-150 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 SUPERFAMILY SSF54665 10 160 9.94E-28 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Gene3D G3DSA:3.30.365.10 277 441 9.6E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Gene3D G3DSA:3.90.1170.50 13 138 9.8E-20 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 SUPERFAMILY SSF56003 130 781 9.42E-176 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Gene3D G3DSA:3.30.365.10 452 621 6.6E-38 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS15090 1871a8022f6b9e96c8b167b95ce7c42d 800 Gene3D G3DSA:3.30.365.10 622 787 4.0E-46 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 SUPERFAMILY SSF53223 11 162 8.63E-51 T 28-03-2018 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 SMART SM00919 164 401 1.6E-130 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 SUPERFAMILY SSF53659 431 760 9.87E-84 T 28-03-2018 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 SMART SM01274 19 152 2.1E-74 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Gene3D G3DSA:3.40.50.10380 6 161 3.2E-32 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Pfam PF00390 Malic enzyme, N-terminal domain 21 152 1.6E-24 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Pfam PF01515 Phosphate acetyl/butaryl transferase 433 756 5.4E-91 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Gene3D G3DSA:3.40.50.720 162 451 6.5E-81 T 28-03-2018 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 2.5E-21 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 Gene3D G3DSA:3.40.718.10 452 730 3.0E-48 T 28-03-2018 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 PIRSF PIRSF036684 1 762 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 AFA_RS03975 946ece46117b98681b322d0affa73d2e 762 SUPERFAMILY SSF51735 164 439 4.11E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 SUPERFAMILY SSF56645 76 284 7.46E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 SUPERFAMILY SSF47203 286 434 4.35E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 175 266 2.5E-14 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 Gene3D G3DSA:2.40.110.10 175 270 3.9E-19 T 28-03-2018 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 Gene3D G3DSA:1.20.140.10 271 441 3.7E-33 T 28-03-2018 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 431 3.3E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS04715 a831412dfe7ebaeb66b78910feb6f9ba 533 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 390 409 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFA_RS09380 81eb09f53c8eaa46c0fcb45b1fb616d8 294 SUPERFAMILY SSF161098 55 282 8.37E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09380 81eb09f53c8eaa46c0fcb45b1fb616d8 294 Gene3D G3DSA:1.10.3720.10 12 294 1.2E-45 T 28-03-2018 AFA_RS09380 81eb09f53c8eaa46c0fcb45b1fb616d8 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 292 1.1E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08910 5c9bba6c7de2dcb82c8cbc7e49f6d1b9 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 2.5E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08910 5c9bba6c7de2dcb82c8cbc7e49f6d1b9 313 Gene3D G3DSA:1.10.3720.10 4 301 2.0E-42 T 28-03-2018 AFA_RS08910 5c9bba6c7de2dcb82c8cbc7e49f6d1b9 313 SUPERFAMILY SSF161098 90 295 6.67E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07615 e49d69464deb8e65500ec5742a01ed2a 307 SUPERFAMILY SSF54060 91 300 3.83E-55 T 28-03-2018 AFA_RS07615 e49d69464deb8e65500ec5742a01ed2a 307 SMART SM00477 113 304 2.5E-25 T 28-03-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 AFA_RS07615 e49d69464deb8e65500ec5742a01ed2a 307 Pfam PF01223 DNA/RNA non-specific endonuclease 106 272 1.7E-43 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 AFA_RS07615 e49d69464deb8e65500ec5742a01ed2a 307 Gene3D G3DSA:3.40.570.10 99 305 9.2E-52 T 28-03-2018 AFA_RS07615 e49d69464deb8e65500ec5742a01ed2a 307 SMART SM00892 112 304 1.2E-34 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 AFA_RS09590 306b89a8de3a320460ded520f25f8aad 184 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 23 132 1.4E-29 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 AFA_RS09590 306b89a8de3a320460ded520f25f8aad 184 Pfam PF11990 Protein of unknown function (DUF3487) 25 133 5.2E-26 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 AFA_RS01710 4705088baaa65cd6137ecba9206b6bdf 180 Pfam PF07291 Methylamine utilisation protein MauE 2 167 1.3E-24 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 Gene3D G3DSA:3.40.50.300 1 256 1.6E-81 T 28-03-2018 AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 Pfam PF00005 ABC transporter 21 169 8.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 Pfam PF09383 NIL domain 262 333 8.0E-19 T 28-03-2018 IPR018449 NIL domain AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 SMART SM00382 30 217 2.9E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 SUPERFAMILY SSF55021 260 334 5.38E-14 T 28-03-2018 AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 SMART SM00930 259 334 2.4E-17 T 28-03-2018 IPR018449 NIL domain AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 Gene3D G3DSA:3.30.70.260 257 336 2.7E-19 T 28-03-2018 AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 SUPERFAMILY SSF52540 1 240 2.32E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03760 6286c0e2341ac0f726a0e6f91375edde 336 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS15590 048e82cd6fc1ee36ab55f32c9a2c31ff 182 SMART SM01322 1 177 1.5E-96 T 28-03-2018 IPR009822 YaeQ AFA_RS15590 048e82cd6fc1ee36ab55f32c9a2c31ff 182 PIRSF PIRSF011484 1 181 1.4E-63 T 28-03-2018 IPR009822 YaeQ AFA_RS15590 048e82cd6fc1ee36ab55f32c9a2c31ff 182 Pfam PF07152 YaeQ protein 1 174 3.0E-68 T 28-03-2018 IPR009822 YaeQ AFA_RS15590 048e82cd6fc1ee36ab55f32c9a2c31ff 182 SUPERFAMILY SSF52980 2 178 2.95E-63 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS15590 048e82cd6fc1ee36ab55f32c9a2c31ff 182 Gene3D G3DSA:3.10.640.10 1 175 3.7E-68 T 28-03-2018 AFA_RS17050 76d6d8c600fe55ffb1651d300dc83084 287 SUPERFAMILY SSF103481 182 281 3.4E-9 T 28-03-2018 AFA_RS17050 76d6d8c600fe55ffb1651d300dc83084 287 Pfam PF00892 EamA-like transporter family 8 132 1.1E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS17050 76d6d8c600fe55ffb1651d300dc83084 287 Pfam PF00892 EamA-like transporter family 149 281 1.2E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS17050 76d6d8c600fe55ffb1651d300dc83084 287 SUPERFAMILY SSF103481 42 134 6.15E-8 T 28-03-2018 AFA_RS10945 d53ab9b25de059a79c3c9cf2600c6162 178 Pfam PF00719 Inorganic pyrophosphatase 18 171 5.9E-50 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFA_RS10945 d53ab9b25de059a79c3c9cf2600c6162 178 SUPERFAMILY SSF50324 4 173 5.49E-63 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFA_RS10945 d53ab9b25de059a79c3c9cf2600c6162 178 Gene3D G3DSA:3.90.80.10 2 178 1.7E-51 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFA_RS10945 d53ab9b25de059a79c3c9cf2600c6162 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 33.553 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFA_RS10945 d53ab9b25de059a79c3c9cf2600c6162 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 65 71 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Gene3D G3DSA:2.40.30.10 101 197 3.1E-18 T 28-03-2018 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 SUPERFAMILY SSF63380 101 197 6.81E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 SUPERFAMILY SSF52343 202 331 2.62E-33 T 28-03-2018 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 234 243 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 134 146 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 150 157 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 193 202 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 209 228 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 2.2E-20 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Pfam PF00175 Oxidoreductase NAD-binding domain 211 310 1.5E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 SUPERFAMILY SSF54292 5 90 1.23E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Pfam PF00970 Oxidoreductase FAD-binding domain 108 198 5.0E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 82 2.1E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 150 157 8.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 209 228 8.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 234 243 8.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Gene3D G3DSA:3.10.20.30 2 98 6.1E-20 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS02200 dcea6a97971f7455ffc183168a299add 333 Gene3D G3DSA:3.40.50.80 200 332 4.5E-24 T 28-03-2018 AFA_RS10465 7e4d297d22281f88ae06cac12a06f513 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 257 1.4E-78 T 28-03-2018 AFA_RS10465 7e4d297d22281f88ae06cac12a06f513 260 SUPERFAMILY SSF56219 1 258 4.19E-80 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS10465 7e4d297d22281f88ae06cac12a06f513 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 2.6E-75 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFA_RS10465 7e4d297d22281f88ae06cac12a06f513 260 Gene3D G3DSA:3.60.10.10 1 259 9.1E-53 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS10465 7e4d297d22281f88ae06cac12a06f513 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 250 9.5E-20 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS16235 8b65ef09e85c4b394cf6b0d7cedb990f 143 Gene3D G3DSA:3.10.180.10 1 134 1.8E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS16235 8b65ef09e85c4b394cf6b0d7cedb990f 143 SUPERFAMILY SSF54593 8 138 9.76E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS12510 9b809e8207d11ee9a3dac9072c3b2ba6 283 Pfam PF04228 Putative neutral zinc metallopeptidase 1 276 3.7E-112 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative AFA_RS17870 299da5e19ab4d514bcb38c7f6b58cdb3 403 Gene3D G3DSA:1.20.1250.20 213 402 3.8E-19 T 28-03-2018 AFA_RS17870 299da5e19ab4d514bcb38c7f6b58cdb3 403 SUPERFAMILY SSF103473 22 399 1.31E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17870 299da5e19ab4d514bcb38c7f6b58cdb3 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 98 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS17870 299da5e19ab4d514bcb38c7f6b58cdb3 403 Gene3D G3DSA:1.20.1250.20 17 212 1.1E-29 T 28-03-2018 AFA_RS17870 299da5e19ab4d514bcb38c7f6b58cdb3 403 Pfam PF07690 Major Facilitator Superfamily 30 334 1.1E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 Gene3D G3DSA:4.10.450.10 36 104 1.2E-25 T 28-03-2018 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 Pfam PF00732 GMC oxidoreductase 5 296 8.9E-82 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 SUPERFAMILY SSF54373 291 474 3.53E-46 T 28-03-2018 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 Pfam PF05199 GMC oxidoreductase 388 526 2.0E-41 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 PIRSF PIRSF000137 2 317 6.3E-89 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 PIRSF PIRSF000137 358 533 9.9E-56 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 SUPERFAMILY SSF51905 473 532 9.55E-83 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 SUPERFAMILY SSF51905 1 289 9.55E-83 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00040 0a99451deafcf7e672a52bde6ceca100 533 Gene3D G3DSA:3.30.560.10 105 489 6.0E-105 T 28-03-2018 AFA_RS08470 beb0e5bd0a26748d38a0370365f577d2 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 225 6.3E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08470 beb0e5bd0a26748d38a0370365f577d2 244 Gene3D G3DSA:1.10.3720.10 11 239 2.6E-38 T 28-03-2018 AFA_RS08470 beb0e5bd0a26748d38a0370365f577d2 244 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 80 2.2E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS08470 beb0e5bd0a26748d38a0370365f577d2 244 SUPERFAMILY SSF161098 15 223 4.45E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07205 4e8c09c1762205ba16636bd792f26e2d 482 SUPERFAMILY SSF55073 316 472 2.28E-46 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS07205 4e8c09c1762205ba16636bd792f26e2d 482 Gene3D G3DSA:3.30.70.270 304 477 8.8E-56 T 28-03-2018 AFA_RS07205 4e8c09c1762205ba16636bd792f26e2d 482 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 307 471 1.4E-48 T 28-03-2018 IPR000160 GGDEF domain AFA_RS07205 4e8c09c1762205ba16636bd792f26e2d 482 SMART SM00267 300 473 7.3E-62 T 28-03-2018 IPR000160 GGDEF domain AFA_RS07205 4e8c09c1762205ba16636bd792f26e2d 482 Pfam PF00990 Diguanylate cyclase, GGDEF domain 311 469 4.4E-46 T 28-03-2018 IPR000160 GGDEF domain AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 66 272 8.3E-59 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 64 274 35.494 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 195 210 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 Gene3D G3DSA:3.40.50.150 58 274 1.4E-35 T 28-03-2018 AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 71 269 7.4E-58 T 28-03-2018 AFA_RS10585 f9b97a3fc730b2ec52d95812a8a1baa3 274 SUPERFAMILY SSF53335 69 271 3.53E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 120 3.9E-12 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 SUPERFAMILY SSF51735 7 156 1.57E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 PIRSF PIRSF015689 4 315 1.4E-130 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 SMART SM00859 8 124 1.1E-11 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 SUPERFAMILY SSF55347 132 285 9.15E-65 T 28-03-2018 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 Gene3D G3DSA:3.30.360.10 146 285 1.6E-65 T 28-03-2018 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 7 309 1.4E-140 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 132 285 4.5E-61 T 28-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 315 143.039 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 AFA_RS13945 54e186e7a67aca6632f1760ee21d6926 315 Gene3D G3DSA:3.40.50.720 2 145 1.6E-12 T 28-03-2018 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 265 9.9E-76 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Gene3D G3DSA:3.40.50.300 402 698 1.2E-48 T 28-03-2018 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Pfam PF13361 UvrD-like helicase C-terminal domain 271 633 6.7E-70 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Gene3D G3DSA:3.40.50.300 141 275 7.0E-31 T 28-03-2018 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Gene3D G3DSA:3.40.50.300 1 140 5.2E-25 T 28-03-2018 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 Gene3D G3DSA:3.40.50.300 276 378 3.1E-26 T 28-03-2018 AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 SUPERFAMILY SSF52540 3 519 1.05E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07535 286a9e61bc591be2da6474d9b20b3887 764 SUPERFAMILY SSF52540 570 658 1.05E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15975 a0775e84ba29f1d5a0d879612c25cac7 276 Pfam PF03781 Sulfatase-modifying factor enzyme 1 80 273 1.9E-31 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFA_RS15975 a0775e84ba29f1d5a0d879612c25cac7 276 Gene3D G3DSA:3.90.1580.10 96 276 1.0E-21 T 28-03-2018 AFA_RS15975 a0775e84ba29f1d5a0d879612c25cac7 276 SUPERFAMILY SSF56436 77 275 2.83E-28 T 28-03-2018 IPR016187 C-type lectin fold AFA_RS04970 27a2a99ec93dc6f4e811971879409c09 291 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 26 268 37.12 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD AFA_RS04970 27a2a99ec93dc6f4e811971879409c09 291 Gene3D G3DSA:1.25.20.10 56 273 5.4E-19 T 28-03-2018 AFA_RS04970 27a2a99ec93dc6f4e811971879409c09 291 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 30 273 2.2E-81 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD AFA_RS04970 27a2a99ec93dc6f4e811971879409c09 291 Pfam PF13525 Outer membrane lipoprotein 57 262 1.2E-58 T 28-03-2018 AFA_RS09510 a10cfeabf0c6374dc648014448544a84 355 Pfam PF11740 Plasmid replication region DNA-binding N-term 33 139 3.1E-17 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain AFA_RS16075 2a5fed6c8e3f221a0673ecd58755ea94 251 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 248 31.046 T 28-03-2018 IPR009777 Cell division protein ZapD AFA_RS16075 2a5fed6c8e3f221a0673ecd58755ea94 251 Gene3D G3DSA:2.60.440.10 172 248 1.4E-26 T 28-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain AFA_RS16075 2a5fed6c8e3f221a0673ecd58755ea94 251 Pfam PF07072 Cell division protein 16 224 2.0E-71 T 28-03-2018 IPR009777 Cell division protein ZapD AFA_RS16075 2a5fed6c8e3f221a0673ecd58755ea94 251 SUPERFAMILY SSF160950 2 248 2.48E-78 T 28-03-2018 IPR009777 Cell division protein ZapD AFA_RS16075 2a5fed6c8e3f221a0673ecd58755ea94 251 Gene3D G3DSA:1.10.3900.10 10 171 5.0E-57 T 28-03-2018 AFA_RS10095 759396f295703f09e113f639e57ec8f1 117 Pfam PF03658 RnfH family Ubiquitin 5 95 2.3E-21 T 28-03-2018 IPR005346 RnfH protein AFA_RS10095 759396f295703f09e113f639e57ec8f1 117 Gene3D G3DSA:3.10.20.280 1 96 3.4E-24 T 28-03-2018 IPR005346 RnfH protein AFA_RS10095 759396f295703f09e113f639e57ec8f1 117 Hamap MF_00460 Protein RnfH [rnfH]. 4 108 18.072 T 28-03-2018 IPR005346 RnfH protein AFA_RS10095 759396f295703f09e113f639e57ec8f1 117 Pfam PF01424 R3H domain 69 105 4.7E-5 T 28-03-2018 IPR001374 R3H domain GO:0003676 AFA_RS10095 759396f295703f09e113f639e57ec8f1 117 SUPERFAMILY SSF54285 4 87 5.49E-14 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFA_RS16795 6df55f1c83165bb15205e48c07be3f9c 233 Gene3D G3DSA:3.40.50.300 1 230 4.7E-56 T 28-03-2018 AFA_RS16795 6df55f1c83165bb15205e48c07be3f9c 233 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS16795 6df55f1c83165bb15205e48c07be3f9c 233 Pfam PF00005 ABC transporter 17 149 9.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS16795 6df55f1c83165bb15205e48c07be3f9c 233 SMART SM00382 26 199 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16795 6df55f1c83165bb15205e48c07be3f9c 233 SUPERFAMILY SSF52540 1 205 1.23E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15255 571e1645042af28ab6cacb01369913d2 139 Pfam PF04214 Protein of unknown function, DUF 50 119 3.1E-23 T 28-03-2018 IPR007332 Protein of unknown function DUF411 AFA_RS15255 571e1645042af28ab6cacb01369913d2 139 Gene3D G3DSA:3.40.30.10 20 108 4.7E-4 T 28-03-2018 AFA_RS13385 f3b4dbc74ce358fe599174b3c89d8399 357 Pfam PF00146 NADH dehydrogenase 28 345 1.4E-122 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13385 f3b4dbc74ce358fe599174b3c89d8399 357 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 233 246 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13385 f3b4dbc74ce358fe599174b3c89d8399 357 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 352 24.613 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 Gene3D G3DSA:3.40.630.30 16 207 2.5E-27 T 28-03-2018 AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 SUPERFAMILY SSF101386 243 447 2.14E-40 T 28-03-2018 AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 Pfam PF13302 Acetyltransferase (GNAT) domain 46 175 5.8E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 SUPERFAMILY SSF55729 26 199 7.09E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 Gene3D G3DSA:1.10.4010.10 240 449 6.4E-44 T 28-03-2018 AFA_RS02520 8ffe1f8c4e118985da62a4bd6576fc5c 469 Pfam PF08761 dUTPase 245 402 7.1E-28 T 28-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 AFA_RS10785 5b35a3f2e68e7147b88df9f5dba8a1a3 468 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 179 250 6.7E-22 T 28-03-2018 IPR020012 Motility protein FimV, N-terminal AFA_RS10785 5b35a3f2e68e7147b88df9f5dba8a1a3 468 Gene3D G3DSA:3.10.350.10 169 228 7.6E-8 T 28-03-2018 AFA_RS10785 5b35a3f2e68e7147b88df9f5dba8a1a3 468 Pfam PF01476 LysM domain 174 227 2.3E-4 T 28-03-2018 IPR018392 LysM domain AFA_RS04010 480556a85983e9ff0f299a3ff78e2363 352 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 315 2.9E-38 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS04010 480556a85983e9ff0f299a3ff78e2363 352 Gene3D G3DSA:3.40.190.10 148 331 7.2E-4 T 28-03-2018 AFA_RS04010 480556a85983e9ff0f299a3ff78e2363 352 PIRSF PIRSF039026 1 350 1.1E-94 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 419 1.2E-20 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Gene3D G3DSA:3.40.50.720 2 201 1.9E-38 T 28-03-2018 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 PIRSF PIRSF000124 8 423 7.1E-53 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 PIRSF PIRSF500136 1 426 4.9E-152 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 SUPERFAMILY SSF48179 202 294 2.89E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 292 3.2E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 413 2.7E-120 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 182 4.2E-33 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 SMART SM00984 319 419 1.8E-37 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 SUPERFAMILY SSF52413 302 420 6.8E-30 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Gene3D G3DSA:3.40.50.720 226 424 4.6E-56 T 28-03-2018 AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 SUPERFAMILY SSF51735 9 191 4.49E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02715 c5dd9fce03340305837a9419f7e77658 426 Gene3D G3DSA:1.20.5.170 203 225 2.0E-11 T 28-03-2018 AFA_RS06440 fe1937b76681da9283120a3b54215635 87 Pfam PF17090 Uncharacterised protein family 23 86 4.0E-12 T 28-03-2018 IPR031381 Uncharacterised protein YtcA AFA_RS14935 81557136a9a50090d87ca25bbeea01ba 246 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 8 242 26.824 T 28-03-2018 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 AFA_RS14935 81557136a9a50090d87ca25bbeea01ba 246 Pfam PF07317 Flagellar regulator YcgR 13 118 2.1E-26 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal AFA_RS14935 81557136a9a50090d87ca25bbeea01ba 246 Gene3D G3DSA:2.40.10.220 119 245 1.0E-15 T 28-03-2018 AFA_RS14935 81557136a9a50090d87ca25bbeea01ba 246 Gene3D G3DSA:2.30.110.10 14 118 6.5E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS14935 81557136a9a50090d87ca25bbeea01ba 246 Pfam PF07238 PilZ domain 121 232 3.5E-8 T 28-03-2018 IPR009875 PilZ domain GO:0035438 AFA_RS09410 47c13872683c32644b4f989ae5682d82 254 SMART SM00382 29 230 3.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS09410 47c13872683c32644b4f989ae5682d82 254 SUPERFAMILY SSF52540 3 252 7.99E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09410 47c13872683c32644b4f989ae5682d82 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 2.0E-11 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS09410 47c13872683c32644b4f989ae5682d82 254 Pfam PF00005 ABC transporter 21 180 1.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS09410 47c13872683c32644b4f989ae5682d82 254 Gene3D G3DSA:3.40.50.300 1 253 8.2E-60 T 28-03-2018 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 Gene3D G3DSA:1.20.1560.10 1 293 9.4E-31 T 28-03-2018 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 Pfam PF00664 ABC transporter transmembrane region 3 240 1.4E-27 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 SUPERFAMILY SSF52540 338 538 5.15E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 2 531 2.1E-150 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 SMART SM00382 352 538 2.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 Gene3D G3DSA:3.40.50.300 294 540 5.0E-42 T 28-03-2018 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 SUPERFAMILY SSF90123 2 296 2.22E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS16300 0854e9a577e15ac4cadb0591b087dbec 540 Pfam PF00005 ABC transporter 348 490 8.6E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS06900 35aae03ccc108fc748a25e3f25972356 163 Gene3D G3DSA:3.20.20.70 7 145 8.4E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS06900 35aae03ccc108fc748a25e3f25972356 163 Pfam PF07799 Protein of unknown function (DUF1643) 28 148 8.6E-38 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 390 45.932 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 388 1.1E-72 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 SUPERFAMILY SSF54675 1 133 1.21E-43 T 28-03-2018 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 Gene3D G3DSA:3.20.140.10 1 388 6.0E-98 T 28-03-2018 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 389 4.2E-148 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 SUPERFAMILY SSF51690 117 387 8.83E-88 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS13205 2efbcb6f05bb485ad3cf517cd1052319 391 PIRSF PIRSF000484 1 376 8.2E-69 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 Pfam PF00196 Bacterial regulatory proteins, luxR family 182 236 4.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 Gene3D G3DSA:1.10.10.10 58 242 3.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 SMART SM00421 179 236 1.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 196 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 212 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 224 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS08800 a4591d9445f29415027cb1b44b1f1cd0 254 SUPERFAMILY SSF46894 170 240 2.86E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 Pfam PF03150 Di-haem cytochrome c peroxidase 108 258 1.9E-45 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 Gene3D G3DSA:1.10.760.10 255 394 3.4E-33 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 PIRSF PIRSF000294 91 394 1.6E-74 T 28-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 SUPERFAMILY SSF46626 235 394 6.91E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 Gene3D G3DSA:1.10.760.10 96 254 2.7E-44 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06150 220372d016581eda0fc24104e23ff312 394 SUPERFAMILY SSF46626 98 243 1.3E-40 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS12250 5a1035c530d314919f61c8add8b28cdb 94 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 8 86 3.4E-15 T 28-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system AFA_RS01785 8b79d9973d8c2abda68a4de249f044de 410 Pfam PF02515 CoA-transferase family III 10 384 5.8E-137 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS01785 8b79d9973d8c2abda68a4de249f044de 410 SUPERFAMILY SSF89796 9 406 2.62E-147 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS01785 8b79d9973d8c2abda68a4de249f044de 410 Gene3D G3DSA:3.40.50.10540 4 409 1.8E-159 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 Pfam PF00326 Prolyl oligopeptidase family 422 634 3.9E-48 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 Gene3D G3DSA:2.130.10.120 145 362 1.7E-19 T 28-03-2018 AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 Gene3D G3DSA:3.40.50.1820 363 634 6.4E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 SUPERFAMILY SSF53474 380 633 4.3E-73 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 Gene3D G3DSA:2.140.10.30 21 142 2.8E-4 T 28-03-2018 AFA_RS09430 232db6062e8f1d381331dd1cc6a0d03d 635 SUPERFAMILY SSF82171 57 372 3.53E-14 T 28-03-2018 AFA_RS16530 2cd2a38fc259ac4643a78eace37e0a5a 247 SUPERFAMILY SSF161098 49 232 9.42E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16530 2cd2a38fc259ac4643a78eace37e0a5a 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 242 1.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16530 2cd2a38fc259ac4643a78eace37e0a5a 247 Gene3D G3DSA:1.10.3720.10 45 244 3.3E-23 T 28-03-2018 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 75 95 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 97 117 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 54 69 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 185 207 1.5E-36 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 SUPERFAMILY SSF50022 8 157 6.55E-46 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 Pfam PF00355 Rieske [2Fe-2S] domain 40 125 3.0E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 SUPERFAMILY SSF55961 160 437 5.26E-49 T 28-03-2018 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 Gene3D G3DSA:2.102.10.10 37 149 1.3E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 198 430 2.9E-10 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS06530 03b5cd351bb297babaef62af353e4175 463 Gene3D G3DSA:3.90.380.10 150 454 3.0E-47 T 28-03-2018 AFA_RS12620 e3001673ff5d6f017885890dada2fa9a 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 2.0E-57 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS12620 e3001673ff5d6f017885890dada2fa9a 130 SUPERFAMILY SSF51182 9 125 7.77E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS12620 e3001673ff5d6f017885890dada2fa9a 130 Pfam PF06339 Ectoine synthase 1 126 1.7E-58 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS12620 e3001673ff5d6f017885890dada2fa9a 130 Gene3D G3DSA:2.60.120.10 2 129 3.9E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS12620 e3001673ff5d6f017885890dada2fa9a 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 40.861 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 164 38.744 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 Gene3D G3DSA:1.10.10.10 81 165 8.8E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 SUPERFAMILY SSF46767 83 164 1.22E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 85 163 1.9E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 84 163 5.5E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 SUPERFAMILY SSF53155 8 89 1.94E-14 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 Gene3D G3DSA:3.30.160.70 7 80 1.5E-15 T 28-03-2018 AFA_RS01690 0f852b8b5c4f7cb97d97e91dce2fb0bf 185 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 80 6.3E-6 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 253 3.5E-78 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 Gene3D G3DSA:3.40.50.150 1 199 1.5E-49 T 28-03-2018 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 250 6.7E-58 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 SMART SM00650 20 188 1.8E-75 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 Gene3D G3DSA:1.10.8.100 200 254 3.9E-15 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 255 52.423 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFA_RS03815 a7c9b0d0ea407f6086d2510a3ec3f4f0 260 SUPERFAMILY SSF53335 4 256 5.28E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS09035 1ec7ad3c1bcadabeaf2d8f1e870d4f1c 139 Gene3D G3DSA:3.10.129.10 2 138 1.5E-24 T 28-03-2018 AFA_RS09035 1ec7ad3c1bcadabeaf2d8f1e870d4f1c 139 Pfam PF03061 Thioesterase superfamily 55 125 3.0E-10 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS09035 1ec7ad3c1bcadabeaf2d8f1e870d4f1c 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 131 2.4E-12 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFA_RS09035 1ec7ad3c1bcadabeaf2d8f1e870d4f1c 139 SUPERFAMILY SSF54637 13 137 4.64E-23 T 28-03-2018 IPR029069 HotDog domain AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 3.2E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 3.2E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 3.2E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 SUPERFAMILY SSF51569 2 290 1.47E-56 T 28-03-2018 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 Gene3D G3DSA:3.20.20.70 2 294 3.3E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 Pfam PF00701 Dihydrodipicolinate synthetase family 4 287 1.5E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 PIRSF PIRSF001365 1 296 2.2E-56 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS01685 622de46c0cf0bafff76d97ce58042cb6 301 SMART SM01130 2 290 5.2E-47 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Gene3D G3DSA:1.10.268.10 376 505 3.0E-48 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 852 0.0 T 28-03-2018 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 3.1E-153 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Gene3D G3DSA:2.120.10.90 545 869 2.1E-131 T 28-03-2018 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 SUPERFAMILY SSF101904 545 864 4.19E-111 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 854 24.06 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 SMART SM00434 11 507 1.2E-284 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Gene3D G3DSA:3.90.199.10 286 375 2.6E-10 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 SUPERFAMILY SSF56719 30 523 6.54E-176 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 750 2.7E-14 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 596 3.8E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 645 8.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 806 852 2.2E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 657 700 3.9E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 802 9.3E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFA_RS11990 eba7bd114f8712bdfea619672ca3b424 894 Gene3D G3DSA:3.90.199.10 34 285 7.4E-116 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 14 568 5.9E-127 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 PRINTS PR01009 Flagellar M-ring protein signature 194 212 2.4E-32 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 PRINTS PR01009 Flagellar M-ring protein signature 119 137 2.4E-32 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 PRINTS PR01009 Flagellar M-ring protein signature 151 165 2.4E-32 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 PRINTS PR01009 Flagellar M-ring protein signature 386 410 2.4E-32 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 PIRSF PIRSF004862 1 570 8.9E-144 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 Pfam PF01514 Secretory protein of YscJ/FliF family 30 218 5.7E-75 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 Pfam PF08345 Flagellar M-ring protein C-terminal 249 457 8.2E-44 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal AFA_RS05960 b501c0f64ebca67feb78887eb6a079b1 574 Gene3D G3DSA:3.30.70.1530 50 113 2.0E-10 T 28-03-2018 AFA_RS10685 b503e294928c4baf8b1adec6993c82cd 268 Gene3D G3DSA:3.20.20.70 2 267 9.8E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS10685 b503e294928c4baf8b1adec6993c82cd 268 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 254 1.4E-103 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFA_RS10685 b503e294928c4baf8b1adec6993c82cd 268 Hamap MF_00443 Thiazole synthase [thiG]. 4 260 41.196 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFA_RS10685 b503e294928c4baf8b1adec6993c82cd 268 SUPERFAMILY SSF110399 3 245 1.19E-84 T 28-03-2018 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 SUPERFAMILY SSF56235 12 535 2.51E-160 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 259 278 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 132 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 47 72 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 1.1E-29 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS04430 2bb492ce1256ce2e1994a8118aea1314 535 Pfam PF01019 Gamma-glutamyltranspeptidase 40 530 3.1E-140 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AFA_RS16910 9ce14d5a3ca348f459dba942c293fa85 634 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 11 631 0.0 T 28-03-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 AFA_RS16910 9ce14d5a3ca348f459dba942c293fa85 634 SUPERFAMILY SSF50974 53 499 3.14E-140 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 AFA_RS16910 9ce14d5a3ca348f459dba942c293fa85 634 Gene3D G3DSA:2.130.10.10 49 500 9.6E-167 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS16910 9ce14d5a3ca348f459dba942c293fa85 634 Gene3D G3DSA:2.60.40.420 501 632 1.4E-31 T 28-03-2018 IPR008972 Cupredoxin AFA_RS16910 9ce14d5a3ca348f459dba942c293fa85 634 SUPERFAMILY SSF49503 504 632 1.43E-35 T 28-03-2018 IPR008972 Cupredoxin AFA_RS16205 618b127869678f3662f0ad2b16cec59c 518 SUPERFAMILY SSF56112 90 153 4.29E-40 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS16205 618b127869678f3662f0ad2b16cec59c 518 SUPERFAMILY SSF56112 188 435 4.29E-40 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS16205 618b127869678f3662f0ad2b16cec59c 518 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 442 1.2E-169 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 AFA_RS16205 618b127869678f3662f0ad2b16cec59c 518 Pfam PF03109 ABC1 family 108 229 2.8E-34 T 28-03-2018 IPR004147 UbiB domain AFA_RS16205 618b127869678f3662f0ad2b16cec59c 518 Gene3D G3DSA:3.30.200.20 98 243 1.2E-21 T 28-03-2018 AFA_RS00145 422d3d9bfb9e65c0362b0b6f9f6cdac7 276 Gene3D G3DSA:3.90.226.10 1 272 9.1E-54 T 28-03-2018 AFA_RS00145 422d3d9bfb9e65c0362b0b6f9f6cdac7 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 238 1.0E-35 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS00145 422d3d9bfb9e65c0362b0b6f9f6cdac7 276 SUPERFAMILY SSF52096 8 263 4.1E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 Gene3D G3DSA:1.10.390.10 277 473 3.0E-22 T 28-03-2018 AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 Pfam PF13180 PDZ domain 505 576 6.8E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 Pfam PF05299 M61 glycyl aminopeptidase 288 404 1.5E-48 T 28-03-2018 IPR007963 Peptidase M61, catalytic domain AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 PIRSF PIRSF016493 2 591 1.0E-207 T 28-03-2018 IPR024191 Peptidase M61 AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 Gene3D G3DSA:2.30.42.10 479 585 4.2E-11 T 28-03-2018 AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 SUPERFAMILY SSF55486 241 423 8.06E-8 T 28-03-2018 AFA_RS16645 955d2e6057c49b7bb5a71ad98fadcf43 591 SUPERFAMILY SSF50156 511 578 1.31E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 AFA_RS17155 afe497b31038a47f362e82e02964a1c2 246 Pfam PF00977 Histidine biosynthesis protein 3 232 7.5E-81 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 AFA_RS17155 afe497b31038a47f362e82e02964a1c2 246 Gene3D G3DSA:3.20.20.70 2 244 5.5E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS17155 afe497b31038a47f362e82e02964a1c2 246 SUPERFAMILY SSF51366 1 240 3.38E-76 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS17155 afe497b31038a47f362e82e02964a1c2 246 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 2.4E-78 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFA_RS17155 afe497b31038a47f362e82e02964a1c2 246 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.701 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 Gene3D G3DSA:3.90.1150.10 395 500 4.5E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 SMART SM00345 28 87 1.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 7.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 Gene3D G3DSA:3.40.640.10 179 394 1.1E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 SUPERFAMILY SSF46785 20 89 3.35E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 Pfam PF00155 Aminotransferase class I and II 169 417 2.6E-22 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 SUPERFAMILY SSF53383 130 498 4.41E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14070 a531cbcee175d7afb71eb4c7b3516f7c 501 Gene3D G3DSA:1.10.10.10 11 89 1.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08915 03118b738169f6d0498c08645b81b70f 279 SUPERFAMILY SSF161098 71 257 2.35E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08915 03118b738169f6d0498c08645b81b70f 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 53 1.9E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFA_RS08915 03118b738169f6d0498c08645b81b70f 279 Gene3D G3DSA:1.10.3720.10 4 265 6.3E-37 T 28-03-2018 AFA_RS08915 03118b738169f6d0498c08645b81b70f 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 275 1.2E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 5 101 29.246 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 SUPERFAMILY SSF47729 7 97 2.5E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 PRINTS PR01727 Prokaryotic integration host factor signature 80 94 9.4E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 PRINTS PR01727 Prokaryotic integration host factor signature 46 61 9.4E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 PRINTS PR01727 Prokaryotic integration host factor signature 64 77 9.4E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 52 71 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 6 97 1.2E-40 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 Gene3D G3DSA:4.10.520.10 5 101 3.1E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 SMART SM00411 7 96 1.8E-39 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS08740 3e0841c002315222d63481fb40c73369 107 Pfam PF00216 Bacterial DNA-binding protein 7 95 5.4E-29 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 SMART SM00357 5 69 8.9E-23 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 67 2.9E-25 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 SUPERFAMILY SSF50249 4 68 2.94E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 PRINTS PR00050 Cold shock protein signature 27 36 6.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 PRINTS PR00050 Cold shock protein signature 42 60 6.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 PRINTS PR00050 Cold shock protein signature 6 21 6.3E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 Gene3D G3DSA:2.40.50.140 2 69 2.0E-24 T 28-03-2018 AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS11195 4ee14abaf4c579e74dd5566d6f5e3fe8 69 PIRSF PIRSF002599 1 69 3.6E-20 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS00955 13034c570cbf774d9b393265e4c399ec 440 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 431 5.6E-75 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00955 13034c570cbf774d9b393265e4c399ec 440 PIRSF PIRSF006066 5 440 2.3E-80 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00955 13034c570cbf774d9b393265e4c399ec 440 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 435 6.4E-83 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 Gene3D G3DSA:3.10.28.20 283 374 3.1E-15 T 28-03-2018 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 Gene3D G3DSA:2.60.120.580 145 272 8.6E-31 T 28-03-2018 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 Gene3D G3DSA:2.60.120.580 3 144 3.7E-31 T 28-03-2018 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 Pfam PF03069 Acetamidase/Formamidase family 8 374 5.3E-152 T 28-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 SUPERFAMILY SSF141130 16 161 2.75E-75 T 28-03-2018 AFA_RS09205 3adc2956f2e522e565769a1126b4d990 399 SUPERFAMILY SSF141130 204 374 2.75E-75 T 28-03-2018 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 SUPERFAMILY SSF55811 17 179 2.03E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 Gene3D G3DSA:2.20.70.10 16 46 2.7E-14 T 28-03-2018 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 Pfam PF00293 NUDIX domain 53 157 1.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 ProSitePatterns PS00893 Nudix box signature. 86 107 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 Gene3D G3DSA:3.90.79.10 47 184 1.1E-30 T 28-03-2018 AFA_RS14330 f08782fc53ab550ad5e5725945ac753a 196 Pfam PF14803 Nudix N-terminal 17 50 2.4E-16 T 28-03-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 AFA_RS17915 fcc7a0df854c581d4ee36260980650d8 452 Pfam PF01578 Cytochrome C assembly protein 190 447 1.5E-47 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFA_RS17915 fcc7a0df854c581d4ee36260980650d8 452 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 160 450 2.1E-75 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 SMART SM00357 5 69 6.0E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 3.4E-27 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 SUPERFAMILY SSF50249 3 68 8.78E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 PRINTS PR00050 Cold shock protein signature 42 60 1.8E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 PRINTS PR00050 Cold shock protein signature 6 21 1.8E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 PRINTS PR00050 Cold shock protein signature 27 36 1.8E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 PIRSF PIRSF002599 1 69 6.0E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS01200 5f9cadd60cba7104ab5b5128e1ebaf38 69 Gene3D G3DSA:2.40.50.140 1 69 6.8E-27 T 28-03-2018 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 Gene3D G3DSA:3.40.50.1360 1 139 1.1E-39 T 28-03-2018 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 219 9.5E-60 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 SUPERFAMILY SSF75445 132 203 5.76E-21 T 28-03-2018 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 222 31.597 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 56 218 6.6E-55 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 SUPERFAMILY SSF100950 3 151 3.14E-42 T 28-03-2018 AFA_RS05335 a60c8ac52e47f38b207ae08fc1b52d93 227 Gene3D G3DSA:3.30.70.260 140 192 1.9E-21 T 28-03-2018 AFA_RS06485 9bbf1c38fe869e6b8414a9162d5a02ea 568 SUPERFAMILY SSF51395 11 502 4.66E-142 T 28-03-2018 AFA_RS06485 9bbf1c38fe869e6b8414a9162d5a02ea 568 Gene3D G3DSA:3.20.20.70 83 501 1.2E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS06485 9bbf1c38fe869e6b8414a9162d5a02ea 568 PIRSF PIRSF500060 11 531 9.1E-238 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria AFA_RS06485 9bbf1c38fe869e6b8414a9162d5a02ea 568 PIRSF PIRSF006429 9 537 2.1E-164 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein AFA_RS06485 9bbf1c38fe869e6b8414a9162d5a02ea 568 Pfam PF01645 Conserved region in glutamate synthase 159 474 7.8E-86 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFA_RS06775 92e1605501f8a0f5d71ea7ff4be60eb7 105 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 26 88 4.0E-15 T 28-03-2018 IPR025474 Domain of unknown function DUF4325 AFA_RS13035 d348722f5583a2a36d391cf3d53132d5 309 Gene3D G3DSA:2.160.10.10 175 297 2.6E-24 T 28-03-2018 AFA_RS13035 d348722f5583a2a36d391cf3d53132d5 309 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 249 283 4.3E-6 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS13035 d348722f5583a2a36d391cf3d53132d5 309 PIRSF PIRSF000441 122 296 9.4E-51 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AFA_RS13035 d348722f5583a2a36d391cf3d53132d5 309 SUPERFAMILY SSF51161 103 292 8.18E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS13035 d348722f5583a2a36d391cf3d53132d5 309 Gene3D G3DSA:1.10.3130.10 43 174 2.1E-39 T 28-03-2018 AFA_RS14560 4bc6940fbdd5ca7e3e9add19facb2213 152 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 145 3.2E-21 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 AFA_RS15200 1a3e087ed82a4a645e3f6668b362b724 253 Gene3D G3DSA:3.40.50.150 12 220 5.1E-13 T 28-03-2018 AFA_RS15200 1a3e087ed82a4a645e3f6668b362b724 253 SUPERFAMILY SSF53335 75 216 1.44E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS15200 1a3e087ed82a4a645e3f6668b362b724 253 Pfam PF08241 Methyltransferase domain 74 124 2.3E-8 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 SUPERFAMILY SSF82051 2 158 4.58E-55 T 28-03-2018 IPR006169 GTP1/OBG domain AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 Pfam PF01018 GTP1/OBG 4 158 7.8E-57 T 28-03-2018 IPR006169 GTP1/OBG domain AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 PIRSF PIRSF002401 1 358 1.8E-132 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 Gene3D G3DSA:3.40.50.300 159 347 1.8E-32 T 28-03-2018 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 Gene3D G3DSA:2.70.210.12 2 156 2.7E-52 T 28-03-2018 IPR006169 GTP1/OBG domain AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 Pfam PF01926 50S ribosome-binding GTPase 161 289 4.1E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 334 1.3E-137 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 SUPERFAMILY SSF52540 151 338 9.66E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.9E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.9E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.9E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.9E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS15775 63a4309d3d4a2a37875708d7cd528e16 362 Hamap MF_01454 GTPase Obg [obg]. 2 336 46.906 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFA_RS01505 88e842ff32e1f3cc7d8a74bfb705be17 324 Gene3D G3DSA:3.40.190.10 133 323 9.1E-31 T 28-03-2018 AFA_RS01505 88e842ff32e1f3cc7d8a74bfb705be17 324 Gene3D G3DSA:3.40.190.10 20 132 9.9E-7 T 28-03-2018 AFA_RS01505 88e842ff32e1f3cc7d8a74bfb705be17 324 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 32 219 3.4E-15 T 28-03-2018 AFA_RS01505 88e842ff32e1f3cc7d8a74bfb705be17 324 SUPERFAMILY SSF53850 25 252 1.37E-33 T 28-03-2018 AFA_RS05810 64f74b044c615fe91684f67d6a5b9e2a 95 Gene3D G3DSA:1.10.287.1160 60 88 3.4E-9 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 AFA_RS05810 64f74b044c615fe91684f67d6a5b9e2a 95 SUPERFAMILY SSF101498 14 90 3.92E-14 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 AFA_RS05810 64f74b044c615fe91684f67d6a5b9e2a 95 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 7 90 9.0E-18 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 AFA_RS05810 64f74b044c615fe91684f67d6a5b9e2a 95 Pfam PF04316 Anti-sigma-28 factor, FlgM 38 87 1.0E-12 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Pfam PF02754 Cysteine-rich domain 170 255 7.5E-12 T 28-03-2018 IPR004017 Cysteine-rich domain AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Pfam PF02754 Cysteine-rich domain 304 386 2.9E-12 T 28-03-2018 IPR004017 Cysteine-rich domain AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 PIRSF PIRSF000139 6 406 4.3E-122 T 28-03-2018 AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Pfam PF13183 4Fe-4S dicluster domain 22 89 9.9E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Gene3D G3DSA:3.30.70.20 82 346 4.7E-5 T 28-03-2018 AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 SUPERFAMILY SSF54862 22 117 7.53E-19 T 28-03-2018 AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Gene3D G3DSA:3.30.70.20 35 81 3.0E-9 T 28-03-2018 AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 Gene3D G3DSA:3.30.70.20 7 34 0.033 T 28-03-2018 AFA_RS05500 d54f092a2fe75e9991cd0e06a441915c 406 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SUPERFAMILY SSF48403 19 223 9.33E-48 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SMART SM00248 93 122 2100.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SMART SM00248 159 193 0.0025 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SMART SM00248 60 89 0.025 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SMART SM00248 24 56 1500.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 SMART SM00248 126 155 0.17 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 Pfam PF12796 Ankyrin repeats (3 copies) 22 91 3.3E-7 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 Pfam PF12796 Ankyrin repeats (3 copies) 103 195 1.0E-13 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 Gene3D G3DSA:1.25.40.20 12 135 4.0E-28 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 Gene3D G3DSA:1.25.40.20 136 224 4.4E-27 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 PRINTS PR01415 Ankyrin repeat signature 127 142 1.3E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09480 2a44279cdd4b75087b31b633ab8d06d1 224 PRINTS PR01415 Ankyrin repeat signature 180 194 1.3E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS09265 b91041adfdbc434bfd2ac34d2889e790 253 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 90 117 1.3E-7 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 AFA_RS09265 b91041adfdbc434bfd2ac34d2889e790 253 Pfam PF00293 NUDIX domain 127 230 8.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS09265 b91041adfdbc434bfd2ac34d2889e790 253 Gene3D G3DSA:3.90.79.10 123 253 1.1E-30 T 28-03-2018 AFA_RS09265 b91041adfdbc434bfd2ac34d2889e790 253 SUPERFAMILY SSF55811 75 230 9.75E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS09265 b91041adfdbc434bfd2ac34d2889e790 253 ProSitePatterns PS00893 Nudix box signature. 156 177 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFA_RS09970 849b2fa0414bde16deca8c8875591b2a 475 Pfam PF06812 ImpA, N-terminal, type VI secretion system 10 121 6.3E-23 T 28-03-2018 IPR010657 ImpA, N-terminal AFA_RS09970 849b2fa0414bde16deca8c8875591b2a 475 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 269 472 5.4E-37 T 28-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 351 35.111 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 38 107 3.1E-17 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 SUPERFAMILY SSF51161 49 341 4.17E-77 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 223 241 0.14 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 286 318 0.091 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 164 1.2E-9 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 167 200 2.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 247 282 5.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 39 354 2.3E-101 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Gene3D G3DSA:2.160.10.10 161 330 1.2E-40 T 28-03-2018 AFA_RS10160 490cb663d0f69266cb76b0824178ba92 377 Gene3D G3DSA:2.160.10.10 115 160 5.5E-10 T 28-03-2018 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 Gene3D G3DSA:1.10.10.60 273 323 1.9E-10 T 28-03-2018 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 Gene3D G3DSA:1.10.260.40 238 272 3.0E-4 T 28-03-2018 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 SMART SM00342 231 314 9.9E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 SUPERFAMILY SSF46689 267 313 1.43E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 Pfam PF12833 Helix-turn-helix domain 237 314 1.5E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 Pfam PF14525 AraC-binding-like domain 20 195 5.6E-37 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 Gene3D G3DSA:1.10.10.60 180 237 5.0E-4 T 28-03-2018 AFA_RS17950 8ee920090aa8a82027ceb6aeb3e5864d 324 SUPERFAMILY SSF46689 215 262 4.76E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS01805 8e93cef73a206b38b8551b61e2dcf3e8 258 SUPERFAMILY SSF53335 17 199 4.76E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS01805 8e93cef73a206b38b8551b61e2dcf3e8 258 Gene3D G3DSA:3.40.50.150 4 252 5.9E-13 T 28-03-2018 AFA_RS05540 09321c9eb6fa6ff8886ea9e23f27779a 369 Gene3D G3DSA:3.10.310.10 178 348 3.2E-49 T 28-03-2018 AFA_RS05540 09321c9eb6fa6ff8886ea9e23f27779a 369 Pfam PF04303 PrpF protein 5 366 1.1E-109 T 28-03-2018 IPR007400 PrpF protein AFA_RS05540 09321c9eb6fa6ff8886ea9e23f27779a 369 Gene3D G3DSA:3.10.310.10 1 177 7.7E-67 T 28-03-2018 AFA_RS05540 09321c9eb6fa6ff8886ea9e23f27779a 369 SUPERFAMILY SSF54506 2 170 9.94E-59 T 28-03-2018 AFA_RS05540 09321c9eb6fa6ff8886ea9e23f27779a 369 SUPERFAMILY SSF54506 174 367 6.28E-53 T 28-03-2018 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 Gene3D G3DSA:3.20.20.100 1 273 2.7E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 Pfam PF00248 Aldo/keto reductase family 19 261 3.9E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 SUPERFAMILY SSF51430 3 271 2.88E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PRINTS PR00069 Aldo-keto reductase signature 38 62 2.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PRINTS PR00069 Aldo-keto reductase signature 126 143 2.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PRINTS PR00069 Aldo-keto reductase signature 160 189 2.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PRINTS PR00069 Aldo-keto reductase signature 94 112 2.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFA_RS17355 0e396608b11c9437b31278637f29ac7e 282 PIRSF PIRSF000097 1 271 1.9E-85 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFA_RS01645 b8c738c1c1b3216bf16e9161f347fbdc 274 SUPERFAMILY SSF161098 71 251 8.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01645 b8c738c1c1b3216bf16e9161f347fbdc 274 Gene3D G3DSA:1.10.3720.10 21 265 1.8E-22 T 28-03-2018 AFA_RS01645 b8c738c1c1b3216bf16e9161f347fbdc 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 264 3.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 Pfam PF00005 ABC transporter 18 157 1.8E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 Gene3D G3DSA:3.40.50.300 1 198 2.5E-34 T 28-03-2018 AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 SUPERFAMILY SSF52540 3 189 9.42E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 SMART SM00382 26 206 4.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02885 6b6294238f1d55b83393ed6d8e24197b 206 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 202 2.2E-59 T 28-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 AFA_RS13615 4835181804987f450d0fb58bfc92013f 118 SUPERFAMILY SSF46626 45 115 1.72E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS13615 4835181804987f450d0fb58bfc92013f 118 Gene3D G3DSA:1.10.760.10 17 116 3.9E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 Gene3D G3DSA:1.10.10.10 5 87 6.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 Gene3D G3DSA:3.40.190.10 176 268 1.4E-17 T 28-03-2018 AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.9E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 SUPERFAMILY SSF46785 4 86 4.39E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 Pfam PF03466 LysR substrate binding domain 93 300 5.2E-24 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 SUPERFAMILY SSF53850 94 303 3.8E-26 T 28-03-2018 AFA_RS17740 10df865401a5dfe091bbdece583a30c5 316 Gene3D G3DSA:3.40.190.10 90 175 9.1E-9 T 28-03-2018 AFA_RS03275 b1e9331ef4524472c8b171d0d5ce4a6d 105 Pfam PF05957 Bacterial protein of unknown function (DUF883) 14 105 1.7E-27 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB AFA_RS06070 30c9f94835eed8fc045e02c1fe96fe4d 529 Gene3D G3DSA:1.20.144.10 40 275 3.6E-4 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFA_RS06070 30c9f94835eed8fc045e02c1fe96fe4d 529 Gene3D G3DSA:3.40.50.410 301 522 3.1E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS06070 30c9f94835eed8fc045e02c1fe96fe4d 529 Pfam PF13519 von Willebrand factor type A domain 358 455 3.1E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS06070 30c9f94835eed8fc045e02c1fe96fe4d 529 SUPERFAMILY SSF53300 365 485 1.78E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS06070 30c9f94835eed8fc045e02c1fe96fe4d 529 SUPERFAMILY SSF53300 313 324 1.78E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS07800 6f69887b9980d987a4cc0779e085b028 277 Pfam PF01026 TatD related DNase 3 264 3.7E-57 T 28-03-2018 IPR001130 TatD family GO:0016788 AFA_RS07800 6f69887b9980d987a4cc0779e085b028 277 SUPERFAMILY SSF51556 2 265 8.41E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS07800 6f69887b9980d987a4cc0779e085b028 277 PIRSF PIRSF005902 1 268 3.0E-58 T 28-03-2018 IPR001130 TatD family GO:0016788 AFA_RS07800 6f69887b9980d987a4cc0779e085b028 277 Gene3D G3DSA:3.20.20.140 1 270 4.0E-67 T 28-03-2018 AFA_RS07800 6f69887b9980d987a4cc0779e085b028 277 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFA_RS17560 87bb623ad31105a3608c5477d63adc27 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 12 293 18.663 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFA_RS17560 87bb623ad31105a3608c5477d63adc27 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site AFA_RS17560 87bb623ad31105a3608c5477d63adc27 297 Pfam PF01040 UbiA prenyltransferase family 28 276 6.6E-57 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFA_RS17560 87bb623ad31105a3608c5477d63adc27 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 15 292 3.8E-91 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFA_RS03210 3e8c1011949cf48bb34ba2acf09751a7 158 Gene3D G3DSA:3.40.390.30 2 158 2.5E-41 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 AFA_RS03210 3e8c1011949cf48bb34ba2acf09751a7 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 153 20.091 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFA_RS03210 3e8c1011949cf48bb34ba2acf09751a7 158 Pfam PF02130 Uncharacterized protein family UPF0054 24 148 2.8E-31 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFA_RS03210 3e8c1011949cf48bb34ba2acf09751a7 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 48 149 4.9E-32 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFA_RS03210 3e8c1011949cf48bb34ba2acf09751a7 158 SUPERFAMILY SSF55486 35 155 2.44E-38 T 28-03-2018 AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 SMART SM00487 11 328 0.0023 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 Gene3D G3DSA:3.40.50.300 10 305 5.7E-14 T 28-03-2018 AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 Gene3D G3DSA:3.40.50.300 516 940 1.3E-8 T 28-03-2018 AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 SUPERFAMILY SSF52540 247 303 8.59E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 SUPERFAMILY SSF52540 15 137 8.59E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 SUPERFAMILY SSF52540 869 929 3.48E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09740 47aa7c8b7b58186d4b08eec45448fb5f 1045 Pfam PF00271 Helicase conserved C-terminal domain 870 921 6.5E-5 T 28-03-2018 IPR001650 Helicase, C-terminal AFA_RS17775 a383fcabf543f0890932d44698c96431 315 PIRSF PIRSF001439 1 311 1.2E-62 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS17775 a383fcabf543f0890932d44698c96431 315 Gene3D G3DSA:3.40.50.720 128 285 5.0E-33 T 28-03-2018 AFA_RS17775 a383fcabf543f0890932d44698c96431 315 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 11 302 8.8E-39 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS17775 a383fcabf543f0890932d44698c96431 315 SUPERFAMILY SSF51735 1 304 2.46E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17775 a383fcabf543f0890932d44698c96431 315 Gene3D G3DSA:3.30.1780.10 1 127 3.5E-35 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 Pfam PF13437 HlyD family secretion protein 307 420 1.1E-15 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 Gene3D G3DSA:1.20.1600.10 274 409 8.9E-12 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 Gene3D G3DSA:1.20.1600.10 113 272 1.2E-10 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 40 453 2.2E-122 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 ProSitePatterns PS00543 HlyD family secretion proteins signature. 417 439 - T 28-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 Pfam PF13533 Biotin-lipoyl like 80 116 6.3E-7 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 SUPERFAMILY SSF111369 72 145 1.31E-5 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 Gene3D G3DSA:2.40.50.100 60 112 2.4E-5 T 28-03-2018 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 50 73 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 319 340 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 432 452 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 417 432 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 376 399 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 92 112 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS18075 12b43e557892bcd357ee8848e722e9fe 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 352 376 5.2E-48 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFA_RS10555 0357142013139d86652c9c817a108fbe 756 Gene3D G3DSA:3.40.50.300 7 617 1.2E-17 T 28-03-2018 AFA_RS10555 0357142013139d86652c9c817a108fbe 756 SUPERFAMILY SSF52540 29 147 6.13E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10555 0357142013139d86652c9c817a108fbe 756 SUPERFAMILY SSF52540 403 596 6.13E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10555 0357142013139d86652c9c817a108fbe 756 Pfam PF13166 AAA domain 17 723 2.4E-130 T 28-03-2018 IPR026866 Protein CR006, P-loop domain AFA_RS17830 88845811466941fd52e3dee67702a59b 246 Pfam PF01925 Sulfite exporter TauE/SafE 17 238 7.6E-9 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 SUPERFAMILY SSF102114 7 312 4.45E-90 T 28-03-2018 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 222 312 7.3E-18 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 SMART SM00876 222 314 1.5E-42 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 Gene3D G3DSA:3.20.20.70 7 317 1.2E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 SMART SM00729 45 257 1.7E-37 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 Pfam PF04055 Radical SAM superfamily 52 204 2.1E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 Hamap MF_01694 Biotin synthase [bioB]. 7 315 41.674 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 PIRSF PIRSF001619 1 321 6.8E-133 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFA_RS03135 4b21698bd42dcd8fdd92a724eb9af5e2 338 TIGRFAM TIGR00433 bioB: biotin synthase 16 312 6.7E-123 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFA_RS12025 2296d1d05dbf06a9b439ead45ea235d9 357 Gene3D G3DSA:3.60.60.10 24 346 5.2E-98 T 28-03-2018 AFA_RS12025 2296d1d05dbf06a9b439ead45ea235d9 357 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 27 313 5.5E-46 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal AFA_RS12025 2296d1d05dbf06a9b439ead45ea235d9 357 SUPERFAMILY SSF56235 27 330 6.94E-94 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10375 f3ab7dd94020aaadb97b9aeb868c3acd 145 SUPERFAMILY SSF50249 43 129 2.06E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS10375 f3ab7dd94020aaadb97b9aeb868c3acd 145 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 78 128 6.5E-12 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFA_RS10375 f3ab7dd94020aaadb97b9aeb868c3acd 145 Gene3D G3DSA:2.40.50.140 77 130 5.1E-7 T 28-03-2018 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 Pfam PF06723 MreB/Mbl protein 11 341 1.5E-147 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 341 5.7E-154 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 Gene3D G3DSA:3.30.420.40 8 173 1.3E-38 T 28-03-2018 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 SUPERFAMILY SSF53067 156 337 1.56E-49 T 28-03-2018 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 SUPERFAMILY SSF53067 9 153 2.11E-37 T 28-03-2018 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 5.2E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 5.2E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 5.2E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 5.2E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 5.2E-62 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 Gene3D G3DSA:3.90.640.10 191 256 3.6E-26 T 28-03-2018 AFA_RS15875 77429c5419ac57e91657461a392cf65e 347 Gene3D G3DSA:3.30.420.40 257 322 2.7E-11 T 28-03-2018 AFA_RS13770 627d5593e515322279a1e9458de3b327 299 Gene3D G3DSA:3.40.50.10330 1 139 2.7E-39 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 AFA_RS13770 627d5593e515322279a1e9458de3b327 299 SUPERFAMILY SSF111331 5 290 4.84E-84 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain AFA_RS13770 627d5593e515322279a1e9458de3b327 299 Gene3D G3DSA:2.60.200.30 140 265 1.3E-36 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFA_RS13770 627d5593e515322279a1e9458de3b327 299 Hamap MF_00361 NAD kinase [nadK]. 4 288 32.232 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFA_RS13770 627d5593e515322279a1e9458de3b327 299 Pfam PF01513 ATP-NAD kinase 57 272 1.8E-52 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFA_RS16970 63b7d3e03b118eb23f0ecf61ac9a92f6 361 Pfam PF13524 Glycosyl transferases group 1 265 356 1.1E-9 T 28-03-2018 AFA_RS16970 63b7d3e03b118eb23f0ecf61ac9a92f6 361 Gene3D G3DSA:3.40.50.2000 107 345 8.5E-6 T 28-03-2018 AFA_RS15165 83c73a1036ce6a3fa1788606739fd772 437 Pfam PF02667 Short chain fatty acid transporter 2 436 9.7E-151 T 28-03-2018 IPR006160 Short chain fatty acid transporter AtoE AFA_RS03565 20c5dd12a877a108b66105f369146035 256 SUPERFAMILY SSF63848 149 254 1.22E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 AFA_RS03565 20c5dd12a877a108b66105f369146035 256 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 151 251 5.5E-32 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 AFA_RS03565 20c5dd12a877a108b66105f369146035 256 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 13 253 2.0E-53 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFA_RS03565 20c5dd12a877a108b66105f369146035 256 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 12 101 2.4E-13 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 AFA_RS03565 20c5dd12a877a108b66105f369146035 256 Gene3D G3DSA:2.160.20.70 132 256 1.0E-33 T 28-03-2018 AFA_RS03565 20c5dd12a877a108b66105f369146035 256 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 12 255 25.31 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 SMART SM00345 93 149 0.37 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 SMART SM00345 12 71 6.5E-4 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 SUPERFAMILY SSF46785 5 66 1.32E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 Pfam PF07729 FCD domain 161 284 1.6E-14 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 SMART SM00895 161 286 3.0E-11 T 28-03-2018 IPR011711 GntR, C-terminal AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 Gene3D G3DSA:1.10.10.10 1 82 1.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 64 2.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 SUPERFAMILY SSF48008 159 290 7.32E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 Gene3D G3DSA:1.10.10.10 83 152 4.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06510 deac0de84c9b506c3d0007032e08d4dc 335 Gene3D G3DSA:1.20.120.530 155 302 1.1E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 162 175 1.7E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 85 96 1.7E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 152 1.7E-12 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 56 278 1.4E-58 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 Gene3D G3DSA:3.40.710.10 27 299 1.0E-44 T 28-03-2018 AFA_RS09090 c37ca1ff1b82e0c94092a77b04077d84 304 SUPERFAMILY SSF56601 57 294 2.95E-54 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS05280 906daf616cb3e49647d14154111e0976 286 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 2 279 8.6E-97 T 28-03-2018 IPR017827 Squalene synthase HpnC AFA_RS05280 906daf616cb3e49647d14154111e0976 286 Pfam PF00494 Squalene/phytoene synthase 5 269 1.2E-55 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 AFA_RS05280 906daf616cb3e49647d14154111e0976 286 Gene3D G3DSA:1.10.600.10 3 285 2.2E-66 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS05280 906daf616cb3e49647d14154111e0976 286 SUPERFAMILY SSF48576 5 282 8.06E-65 T 28-03-2018 IPR008949 Isoprenoid synthase domain AFA_RS13070 def772d23980483b9fa097d165e63600 597 SUPERFAMILY SSF54980 399 493 1.29E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS13070 def772d23980483b9fa097d165e63600 597 SMART SM00838 401 485 0.0046 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS13070 def772d23980483b9fa097d165e63600 597 Gene3D G3DSA:3.30.70.870 288 367 2.0E-27 T 28-03-2018 AFA_RS13070 def772d23980483b9fa097d165e63600 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 1.1E-49 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal AFA_RS13070 def772d23980483b9fa097d165e63600 597 Pfam PF00679 Elongation factor G C-terminus 400 484 4.0E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like AFA_RS13070 def772d23980483b9fa097d165e63600 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 3.4E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 9.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 9.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 9.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 9.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 9.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 1.5E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 1.4E-299 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 SUPERFAMILY SSF52540 2 205 1.54E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13070 def772d23980483b9fa097d165e63600 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 302.091 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 Gene3D G3DSA:3.30.70.240 390 549 8.8E-26 T 28-03-2018 AFA_RS13070 def772d23980483b9fa097d165e63600 597 Gene3D G3DSA:3.40.50.300 1 190 5.8E-37 T 28-03-2018 AFA_RS13070 def772d23980483b9fa097d165e63600 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 176 7.1E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFA_RS13070 def772d23980483b9fa097d165e63600 597 SUPERFAMILY SSF54980 292 370 7.55E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like AFA_RS13070 def772d23980483b9fa097d165e63600 597 Gene3D G3DSA:2.40.30.10 191 287 2.5E-22 T 28-03-2018 AFA_RS13070 def772d23980483b9fa097d165e63600 597 SUPERFAMILY SSF50447 165 288 5.3E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS13070 def772d23980483b9fa097d165e63600 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site AFA_RS15035 663886dd00ee577dea6a4acafb8fecbc 297 Hamap MF_01818 Ribonuclease BN [rbn]. 1 297 23.412 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFA_RS15035 663886dd00ee577dea6a4acafb8fecbc 297 SUPERFAMILY SSF56281 2 296 2.03E-59 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15035 663886dd00ee577dea6a4acafb8fecbc 297 Gene3D G3DSA:3.60.15.10 1 297 2.8E-55 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15035 663886dd00ee577dea6a4acafb8fecbc 297 Pfam PF12706 Beta-lactamase superfamily domain 31 243 3.2E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15035 663886dd00ee577dea6a4acafb8fecbc 297 SMART SM00849 18 242 2.0E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00965 4ae367ac7582b140da2df2054e678a95 386 Gene3D G3DSA:3.40.47.10 217 384 2.8E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00965 4ae367ac7582b140da2df2054e678a95 386 Gene3D G3DSA:3.40.47.10 19 216 6.3E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00965 4ae367ac7582b140da2df2054e678a95 386 SUPERFAMILY SSF53901 182 370 1.22E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00965 4ae367ac7582b140da2df2054e678a95 386 SUPERFAMILY SSF53901 28 118 1.22E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00965 4ae367ac7582b140da2df2054e678a95 386 PIRSF PIRSF000429 7 375 8.3E-19 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS07090 c0505ccad933d236ace9a7a728fb0dc7 113 Pfam PF05939 Phage minor tail protein 3 110 1.3E-30 T 28-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 SUPERFAMILY SSF46785 4 89 1.69E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 Gene3D G3DSA:1.10.10.10 1 84 1.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 SUPERFAMILY SSF53850 90 287 1.36E-26 T 28-03-2018 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 Gene3D G3DSA:3.40.190.10 90 179 7.3E-11 T 28-03-2018 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 Gene3D G3DSA:3.40.190.10 180 257 1.3E-7 T 28-03-2018 AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 Pfam PF03466 LysR substrate binding domain 88 285 1.3E-21 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS12010 2a12a759f74249b2a455a25517592b44 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS10620 74b86c1530f7715de9e08a1f4476ccb6 176 SUPERFAMILY SSF52833 14 156 6.71E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS10620 74b86c1530f7715de9e08a1f4476ccb6 176 Pfam PF08534 Redoxin 15 132 3.0E-8 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFA_RS10620 74b86c1530f7715de9e08a1f4476ccb6 176 Gene3D G3DSA:3.40.30.10 8 149 1.0E-16 T 28-03-2018 AFA_RS10565 6b172f6edaab70bdec09f7f09a1e5db3 446 Gene3D G3DSA:3.50.50.60 24 416 1.3E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10565 6b172f6edaab70bdec09f7f09a1e5db3 446 Pfam PF01266 FAD dependent oxidoreductase 39 394 1.5E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS10565 6b172f6edaab70bdec09f7f09a1e5db3 446 SUPERFAMILY SSF51905 36 337 8.29E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 Pfam PF00535 Glycosyl transferase family 2 411 568 7.5E-10 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 SUPERFAMILY SSF53448 409 608 2.65E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 Gene3D G3DSA:3.90.550.10 407 619 1.9E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 Gene3D G3DSA:3.40.50.2000 237 386 3.0E-8 T 28-03-2018 AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 Pfam PF13524 Glycosyl transferases group 1 304 394 1.1E-11 T 28-03-2018 AFA_RS16995 5b12076822a84900ba31be9cdf11e987 639 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 165 238 1.4E-6 T 28-03-2018 IPR024542 Domain of unknown function DUF3880 AFA_RS01600 5906a36afe2650bfdbf2d6284c1a96f8 368 Pfam PF04235 Protein of unknown function (DUF418) 208 363 4.0E-24 T 28-03-2018 IPR007349 Domain of unknown function DUF418 AFA_RS12075 53815cf36243ba04ca2075e13a1a904f 151 Pfam PF01575 MaoC like domain 16 124 1.3E-11 T 28-03-2018 IPR002539 MaoC-like domain AFA_RS12075 53815cf36243ba04ca2075e13a1a904f 151 SUPERFAMILY SSF54637 8 150 1.82E-29 T 28-03-2018 IPR029069 HotDog domain AFA_RS12075 53815cf36243ba04ca2075e13a1a904f 151 Gene3D G3DSA:3.10.129.10 3 144 7.4E-28 T 28-03-2018 AFA_RS02190 cf74e61eecccc9c7db35e609c6612b9f 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.4E-55 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02190 cf74e61eecccc9c7db35e609c6612b9f 325 Gene3D G3DSA:3.40.190.10 132 292 3.2E-7 T 28-03-2018 AFA_RS02190 cf74e61eecccc9c7db35e609c6612b9f 325 SUPERFAMILY SSF53850 115 288 1.59E-6 T 28-03-2018 AFA_RS02190 cf74e61eecccc9c7db35e609c6612b9f 325 PIRSF PIRSF017082 1 323 5.1E-65 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS06165 d5e8ac3f4544ad7c8fc5585e98ae8d8d 440 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 434 1.4E-91 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS06165 d5e8ac3f4544ad7c8fc5585e98ae8d8d 440 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 429 4.9E-85 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS06165 d5e8ac3f4544ad7c8fc5585e98ae8d8d 440 PIRSF PIRSF006066 5 440 3.7E-73 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS05330 ad7050b90085ee2762924d55c03181f4 114 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 1 108 5.8E-29 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR AFA_RS05330 ad7050b90085ee2762924d55c03181f4 114 SUPERFAMILY SSF52833 1 110 2.12E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS05330 ad7050b90085ee2762924d55c03181f4 114 Gene3D G3DSA:3.40.30.10 1 112 1.5E-30 T 28-03-2018 AFA_RS05330 ad7050b90085ee2762924d55c03181f4 114 Pfam PF03960 ArsC family 2 109 1.3E-13 T 28-03-2018 IPR006660 Arsenate reductase-like AFA_RS06340 3059ce0c5b42ab322cbb4a8950bf26af 234 Pfam PF04335 VirB8 protein 23 225 1.1E-70 T 28-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 AFA_RS06340 3059ce0c5b42ab322cbb4a8950bf26af 234 SUPERFAMILY SSF54427 94 226 4.29E-28 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS05020 002c4555361a32a85b26e41c201bfe54 151 SUPERFAMILY SSF53955 7 150 1.74E-50 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS05020 002c4555361a32a85b26e41c201bfe54 151 Gene3D G3DSA:1.10.530.40 3 151 1.7E-47 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 AFA_RS05020 002c4555361a32a85b26e41c201bfe54 151 Pfam PF00959 Phage lysozyme 35 140 2.9E-19 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 AFA_RS11090 9e3202a6817cb9c735944e5ce1b78962 382 Gene3D G3DSA:3.20.20.70 4 371 5.0E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS11090 9e3202a6817cb9c735944e5ce1b78962 382 Pfam PF03060 Nitronate monooxygenase 9 300 3.9E-32 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFA_RS11090 9e3202a6817cb9c735944e5ce1b78962 382 SUPERFAMILY SSF51412 9 297 3.05E-37 T 28-03-2018 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 SUPERFAMILY SSF50331 204 269 2.04E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 130 196 1.5E-21 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 203 268 7.7E-21 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Gene3D G3DSA:2.40.50.100 130 197 1.8E-21 T 28-03-2018 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 SUPERFAMILY SSF46785 12 128 1.47E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 89 2.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Gene3D G3DSA:1.10.10.10 6 115 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Pfam PF03459 TOBE domain 132 195 1.2E-17 T 28-03-2018 IPR005116 Transport-associated OB, type 1 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Pfam PF03459 TOBE domain 205 267 1.0E-17 T 28-03-2018 IPR005116 Transport-associated OB, type 1 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 Gene3D G3DSA:2.40.50.100 202 269 9.8E-22 T 28-03-2018 AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 SUPERFAMILY SSF50331 130 200 3.16E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFA_RS04070 d95964af2eacf0854020da3c2ec17bc9 270 PIRSF PIRSF005763 8 270 1.6E-87 T 28-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 Gene3D G3DSA:3.30.230.40 1 88 2.4E-35 T 28-03-2018 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 174 3.3E-61 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 SUPERFAMILY SSF54211 1 85 6.58E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 41.648 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 SUPERFAMILY SSF54211 87 179 6.68E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFA_RS17145 06843a98b45c4c387a46f8df43521f10 195 Gene3D G3DSA:3.30.230.40 90 195 6.7E-30 T 28-03-2018 AFA_RS01460 1fcfb03592bd1b1468696c6ccd73c9e7 238 Pfam PF00005 ABC transporter 20 165 4.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01460 1fcfb03592bd1b1468696c6ccd73c9e7 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01460 1fcfb03592bd1b1468696c6ccd73c9e7 238 SUPERFAMILY SSF52540 4 230 5.64E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01460 1fcfb03592bd1b1468696c6ccd73c9e7 238 SMART SM00382 29 215 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01460 1fcfb03592bd1b1468696c6ccd73c9e7 238 Gene3D G3DSA:3.40.50.300 1 235 7.1E-54 T 28-03-2018 AFA_RS15385 35740f8f1b45f81d9ccfb3a4c4efd20b 434 Gene3D G3DSA:3.20.20.140 42 426 2.5E-12 T 28-03-2018 AFA_RS15385 35740f8f1b45f81d9ccfb3a4c4efd20b 434 SUPERFAMILY SSF51556 153 407 1.77E-8 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 Gene3D G3DSA:3.30.1330.60 49 192 4.0E-37 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 150 169 1.5E-5 T 28-03-2018 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 170 190 1.5E-5 T 28-03-2018 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 132 149 1.5E-5 T 28-03-2018 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01021 OMPA domain signature 132 148 2.1E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01021 OMPA domain signature 87 109 2.1E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 PRINTS PR01021 OMPA domain signature 117 132 2.1E-10 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 Pfam PF00691 OmpA family 87 181 1.6E-20 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 Pfam PF13488 Glycine zipper 9 49 7.9E-7 T 28-03-2018 AFA_RS15810 49254eae5846123a90cd30fd5e4534f8 192 SUPERFAMILY SSF103088 75 187 5.76E-36 T 28-03-2018 IPR006665 OmpA-like domain AFA_RS01940 bce065d68830ab2893644f049584575e 174 Gene3D G3DSA:3.40.630.30 4 166 2.9E-33 T 28-03-2018 AFA_RS01940 bce065d68830ab2893644f049584575e 174 Pfam PF00583 Acetyltransferase (GNAT) family 38 144 5.3E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS01940 bce065d68830ab2893644f049584575e 174 SUPERFAMILY SSF55729 8 163 3.38E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS08515 e80095beadad9a20a3a031b92e60a112 335 SUPERFAMILY SSF47240 1 330 2.84E-97 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS08515 e80095beadad9a20a3a031b92e60a112 335 PIRSF PIRSF000040 1 333 5.3E-100 T 28-03-2018 IPR012078 Methane/phenol monooxygenase, hydroxylase component GO:0016709|GO:0055114 AFA_RS08515 e80095beadad9a20a3a031b92e60a112 335 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 51 274 8.2E-59 T 28-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 AFA_RS08515 e80095beadad9a20a3a031b92e60a112 335 Gene3D G3DSA:1.10.620.20 7 327 5.0E-93 T 28-03-2018 AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 PRINTS PR00608 Class II cytochrome C signature 136 147 8.5E-5 T 28-03-2018 IPR015984 Cytochrome c prime, subgroup AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 PRINTS PR00608 Class II cytochrome C signature 113 136 8.5E-5 T 28-03-2018 IPR015984 Cytochrome c prime, subgroup AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 Gene3D G3DSA:1.20.120.10 24 150 2.3E-34 T 28-03-2018 AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 Pfam PF01322 Cytochrome C' 30 147 2.1E-31 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 PIRSF PIRSF000027 8 149 1.2E-36 T 28-03-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFA_RS12530 db4ed6ec6176ed2debc9702effae70f4 150 SUPERFAMILY SSF47175 25 147 7.33E-35 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 AFA_RS00115 31e29c3e8bd474fb32de86984c826ba5 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 304 2.7E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS00115 31e29c3e8bd474fb32de86984c826ba5 326 Gene3D G3DSA:1.10.3470.10 15 319 5.2E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS07875 48c0a314bb3f40f74cab5d1de8b4ef25 78 TIGRFAM TIGR04359 TrbK_RP4: entry exclusion lipoprotein TrbK 7 78 2.6E-16 T 28-03-2018 IPR027584 Entry exclusion lipoprotein TrbK AFA_RS02185 9d5e4f114b6ffdfe569945ee5bc7a458 520 SUPERFAMILY SSF53649 286 492 2.74E-115 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS02185 9d5e4f114b6ffdfe569945ee5bc7a458 520 SUPERFAMILY SSF53649 2 243 2.74E-115 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AFA_RS02185 9d5e4f114b6ffdfe569945ee5bc7a458 520 Gene3D G3DSA:3.40.720.10 1 416 2.1E-84 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS02185 9d5e4f114b6ffdfe569945ee5bc7a458 520 Pfam PF00884 Sulfatase 5 383 1.7E-53 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AFA_RS02185 9d5e4f114b6ffdfe569945ee5bc7a458 520 Gene3D G3DSA:3.30.1120.10 425 511 1.7E-12 T 28-03-2018 AFA_RS03110 71c23e817c6fcaf8a1eb3a39bf4ffa22 211 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 56 179 5.2E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS03795 4174a6c043f11463aa8b8c2ba1221358 236 SUPERFAMILY SSF53448 1 230 1.6E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS03795 4174a6c043f11463aa8b8c2ba1221358 236 Pfam PF00483 Nucleotidyl transferase 3 230 1.3E-24 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFA_RS03795 4174a6c043f11463aa8b8c2ba1221358 236 Gene3D G3DSA:3.90.550.10 1 236 7.3E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS17120 97b6f37cc9a361d9e668d4dcaffc908b 252 PIRSF PIRSF006648 4 249 2.3E-21 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17120 97b6f37cc9a361d9e668d4dcaffc908b 252 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 7.1E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17120 97b6f37cc9a361d9e668d4dcaffc908b 252 PRINTS PR00164 ABC-2 type transport system membrane protein signature 54 76 7.1E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17120 97b6f37cc9a361d9e668d4dcaffc908b 252 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 7.1E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17120 97b6f37cc9a361d9e668d4dcaffc908b 252 Pfam PF01061 ABC-2 type transporter 7 215 1.7E-36 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 122 201 1.4E-9 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 Gene3D G3DSA:3.40.50.720 117 283 7.0E-32 T 28-03-2018 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 279 31.048 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 9 280 6.5E-76 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 Gene3D G3DSA:3.40.50.10860 3 116 6.4E-34 T 28-03-2018 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 3.0E-21 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 SUPERFAMILY SSF53223 5 106 1.21E-26 T 28-03-2018 AFA_RS15685 944f137ca4a034687f73a6bcefa0fd99 283 SUPERFAMILY SSF51735 107 279 5.12E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07265 f7c0eef5b275dd9e4c924ab23b3a8b8c 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 254 8.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07265 f7c0eef5b275dd9e4c924ab23b3a8b8c 262 SUPERFAMILY SSF161098 5 252 3.92E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07265 f7c0eef5b275dd9e4c924ab23b3a8b8c 262 Gene3D G3DSA:1.10.3720.10 5 262 5.2E-38 T 28-03-2018 AFA_RS15445 035c1fc9f391d0a50c5e1d945b2efc84 404 Pfam PF07690 Major Facilitator Superfamily 15 234 2.6E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS15445 035c1fc9f391d0a50c5e1d945b2efc84 404 Gene3D G3DSA:1.20.1250.20 4 204 4.7E-25 T 28-03-2018 AFA_RS15445 035c1fc9f391d0a50c5e1d945b2efc84 404 Gene3D G3DSA:1.20.1250.20 205 402 3.2E-16 T 28-03-2018 AFA_RS15445 035c1fc9f391d0a50c5e1d945b2efc84 404 SUPERFAMILY SSF103473 1 395 1.1E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 SUPERFAMILY SSF52507 1 180 1.7E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 365 2.2E-68 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 Gene3D G3DSA:3.40.50.10300 182 394 1.4E-66 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 Gene3D G3DSA:3.40.50.1950 1 181 5.6E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 Pfam PF02441 Flavoprotein 5 176 7.4E-44 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 390 2.6E-133 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AFA_RS07500 b4ebc586445998bac87238092036ae9b 394 SUPERFAMILY SSF102645 175 393 3.53E-73 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFA_RS12545 2913e1986c9e9cae54375952f32254da 281 SUPERFAMILY SSF46689 216 269 4.93E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS12545 2913e1986c9e9cae54375952f32254da 281 Gene3D G3DSA:1.10.10.60 218 277 4.1E-9 T 28-03-2018 AFA_RS12545 2913e1986c9e9cae54375952f32254da 281 Gene3D G3DSA:1.10.10.60 149 217 0.017 T 28-03-2018 AFA_RS12545 2913e1986c9e9cae54375952f32254da 281 SMART SM00342 179 263 2.8E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS12545 2913e1986c9e9cae54375952f32254da 281 Pfam PF12833 Helix-turn-helix domain 186 265 4.4E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS11575 eaa7de03de517fdd4155551a98f775af 164 Gene3D G3DSA:1.10.260.40 7 94 2.7E-5 T 28-03-2018 AFA_RS11575 eaa7de03de517fdd4155551a98f775af 164 Pfam PF13413 Helix-turn-helix domain 23 82 1.1E-16 T 28-03-2018 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 SMART SM00283 278 525 2.0E-70 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 SUPERFAMILY SSF58104 250 526 2.75E-65 T 28-03-2018 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 337 492 1.2E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 113 1.9E-13 T 28-03-2018 IPR000014 PAS domain AFA_RS06080 06984262e0671659ce23990184e54b9c 551 Gene3D G3DSA:1.10.287.950 220 329 2.2E-7 T 28-03-2018 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 Gene3D G3DSA:1.10.287.950 330 527 3.5E-43 T 28-03-2018 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 SUPERFAMILY SSF55785 20 114 2.09E-25 T 28-03-2018 IPR000014 PAS domain AFA_RS06080 06984262e0671659ce23990184e54b9c 551 Pfam PF08447 PAS fold 30 113 9.5E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 Gene3D G3DSA:3.40.50.10600 2 131 1.4E-26 T 28-03-2018 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 299 328 1.5E-46 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 1.5E-46 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 376 403 1.5E-46 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06080 06984262e0671659ce23990184e54b9c 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 453 482 1.5E-46 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS06040 8323ac325158fe35165779ffe0c3be6c 664 Gene3D G3DSA:3.40.50.410 229 461 2.0E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS06040 8323ac325158fe35165779ffe0c3be6c 664 SUPERFAMILY SSF53300 237 443 3.81E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS06040 8323ac325158fe35165779ffe0c3be6c 664 Pfam PF00092 von Willebrand factor type A domain 238 413 6.1E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A AFA_RS09375 750fffd7ba89e7fc0e95858756af5f16 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 275 5.7E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS09375 750fffd7ba89e7fc0e95858756af5f16 280 Gene3D G3DSA:1.10.3720.10 2 269 5.8E-34 T 28-03-2018 AFA_RS09375 750fffd7ba89e7fc0e95858756af5f16 280 SUPERFAMILY SSF161098 4 276 4.95E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18440 f32ae6c54641c44cb548ffe5e8955411 282 Pfam PF02666 Phosphatidylserine decarboxylase 63 279 1.2E-60 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFA_RS18440 f32ae6c54641c44cb548ffe5e8955411 282 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 279 1.3E-71 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFA_RS18440 f32ae6c54641c44cb548ffe5e8955411 282 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 282 43.749 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 140 151 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 SUPERFAMILY SSF51621 13 944 5.96E-277 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 579 591 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 577 597 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 254 269 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 139 152 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 619 648 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 405 425 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 757 783 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 191 207 1.8E-54 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 Pfam PF00311 Phosphoenolpyruvate carboxylase 136 944 4.8E-274 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 5 944 18.207 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFA_RS02075 ba570693f236acbec17295cfca665f9f 944 Gene3D G3DSA:1.20.1440.90 283 407 4.5E-26 T 28-03-2018 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 Pfam PF01168 Alanine racemase, N-terminal domain 9 236 5.5E-57 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 TIGRFAM TIGR00492 alr: alanine racemase 5 373 9.2E-96 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 Hamap MF_01201 Alanine racemase. 2 375 31.875 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 Gene3D G3DSA:3.20.20.10 6 233 6.9E-35 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 Pfam PF00842 Alanine racemase, C-terminal domain 251 373 4.9E-42 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 SMART SM01005 250 375 2.6E-61 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 Gene3D G3DSA:2.40.37.10 234 376 3.6E-55 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 SUPERFAMILY SSF51419 9 251 4.36E-53 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 SUPERFAMILY SSF50621 244 375 4.88E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 70 88 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 167 178 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 209 236 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 283 298 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 357 370 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 304 321 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 36 52 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 266 281 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS05285 dccef68915fa92689ef5bf8277060fae 376 PRINTS PR00992 Alanine racemase signature 130 142 1.0E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS09595 7f4975a8f2ab3c0502a033421ec52e8e 266 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 7 210 1.1E-71 T 28-03-2018 IPR021548 Protein of unknown function DUF2895 AFA_RS09595 7f4975a8f2ab3c0502a033421ec52e8e 266 Pfam PF11444 Protein of unknown function (DUF2895) 8 209 2.2E-66 T 28-03-2018 IPR021548 Protein of unknown function DUF2895 AFA_RS09960 b752e712ff1432dae0e2fb7905d92edd 495 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 493 5.3E-211 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath AFA_RS09960 b752e712ff1432dae0e2fb7905d92edd 495 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 493 2.9E-179 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath AFA_RS09405 2b7e768d635851dfef60ba0a85a2c474 407 Pfam PF11862 Domain of unknown function (DUF3382) 4 94 5.1E-17 T 28-03-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal AFA_RS09405 2b7e768d635851dfef60ba0a85a2c474 407 Gene3D G3DSA:1.10.3470.10 92 390 6.4E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS09405 2b7e768d635851dfef60ba0a85a2c474 407 Pfam PF02653 Branched-chain amino acid transport system / permease component 104 388 5.6E-51 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS00475 335c02480a05cf4bed47e8b275fc205f 275 Pfam PF03180 NLPA lipoprotein 27 257 3.6E-66 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS00475 335c02480a05cf4bed47e8b275fc205f 275 Gene3D G3DSA:3.40.190.10 26 122 4.9E-19 T 28-03-2018 AFA_RS00475 335c02480a05cf4bed47e8b275fc205f 275 SUPERFAMILY SSF53850 27 246 1.2E-61 T 28-03-2018 AFA_RS00475 335c02480a05cf4bed47e8b275fc205f 275 Gene3D G3DSA:3.40.190.10 123 260 1.3E-33 T 28-03-2018 AFA_RS08530 508a90fd036d3e5e89bb4d9e46f2fe09 120 Pfam PF04663 Phenol hydroxylase conserved region 15 79 1.7E-23 T 28-03-2018 IPR006756 Phenol hydroxylase KEGG: 00623+1.14.13.7|KEGG: 00627+1.14.13.7|MetaCyc: PWY-5418|MetaCyc: PWY-6197 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 SUPERFAMILY SSF50129 1 95 2.35E-32 T 28-03-2018 IPR011032 GroES-like AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 PRINTS PR00297 10kDa chaperonin signature 3 18 3.4E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 PRINTS PR00297 10kDa chaperonin signature 81 94 3.4E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 PRINTS PR00297 10kDa chaperonin signature 60 72 3.4E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 PRINTS PR00297 10kDa chaperonin signature 25 46 3.4E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 25.62 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 Gene3D G3DSA:2.30.33.40 1 95 4.1E-37 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 8.9E-33 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 AFA_RS14815 1848c7ad8bd7b4e4ca7268edeb91823b 95 SMART SM00883 2 94 1.5E-51 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFA_RS12030 43d0db09a6a3b2e5622d40af890e3585 670 Gene3D G3DSA:2.170.130.10 27 167 3.9E-37 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS12030 43d0db09a6a3b2e5622d40af890e3585 670 Pfam PF00593 TonB dependent receptor 221 668 2.0E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS12030 43d0db09a6a3b2e5622d40af890e3585 670 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 160 2.9E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS12030 43d0db09a6a3b2e5622d40af890e3585 670 Gene3D G3DSA:2.40.170.20 171 670 4.1E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS12030 43d0db09a6a3b2e5622d40af890e3585 670 SUPERFAMILY SSF56935 27 670 2.29E-127 T 28-03-2018 AFA_RS15475 6b01ce991d13b2741703f395c4b89e63 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.2E-57 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFA_RS15475 6b01ce991d13b2741703f395c4b89e63 153 Pfam PF03477 ATP cone domain 50 136 3.9E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFA_RS15475 6b01ce991d13b2741703f395c4b89e63 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 81.736 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFA_RS04225 a2c7cee33f235359f0623e489754aea7 133 Gene3D G3DSA:3.10.180.10 7 115 5.2E-4 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS07035 2b4d2c071d6983ff04fcaf09ff2397b4 232 Pfam PF00717 Peptidase S24-like 140 190 1.0E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS07035 2b4d2c071d6983ff04fcaf09ff2397b4 232 Gene3D G3DSA:2.10.109.10 95 226 1.9E-19 T 28-03-2018 AFA_RS07035 2b4d2c071d6983ff04fcaf09ff2397b4 232 SUPERFAMILY SSF51306 98 224 4.84E-22 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 SUPERFAMILY SSF46785 4 113 4.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 Pfam PF03466 LysR substrate binding domain 89 292 1.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 Gene3D G3DSA:3.40.190.10 176 261 6.0E-20 T 28-03-2018 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 Gene3D G3DSA:3.40.190.10 91 175 4.8E-17 T 28-03-2018 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 SUPERFAMILY SSF53850 90 293 2.96E-41 T 28-03-2018 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS17725 f22ac9915ccb20a8ccf7479fb4befc9a 294 Gene3D G3DSA:1.10.10.10 1 87 9.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13425 fc5c6778e9df80d669685440e9129aad 397 Gene3D G3DSA:2.40.160.10 8 397 8.1E-67 T 28-03-2018 AFA_RS13425 fc5c6778e9df80d669685440e9129aad 397 SUPERFAMILY SSF56935 21 397 1.22E-66 T 28-03-2018 AFA_RS13425 fc5c6778e9df80d669685440e9129aad 397 Pfam PF13609 Gram-negative porin 7 377 4.7E-52 T 28-03-2018 AFA_RS13425 fc5c6778e9df80d669685440e9129aad 397 PRINTS PR00184 Neisseria sp. porin signature 167 184 4.1E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AFA_RS13425 fc5c6778e9df80d669685440e9129aad 397 PRINTS PR00184 Neisseria sp. porin signature 66 91 4.1E-8 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AFA_RS12590 e218ebb889bc1bc76bbce72285e26528 223 SUPERFAMILY SSF161098 10 207 2.75E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12590 e218ebb889bc1bc76bbce72285e26528 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 214 1.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS12590 e218ebb889bc1bc76bbce72285e26528 223 Gene3D G3DSA:1.10.3720.10 2 221 2.1E-40 T 28-03-2018 AFA_RS12590 e218ebb889bc1bc76bbce72285e26528 223 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 9 221 4.6E-83 T 28-03-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC AFA_RS12590 e218ebb889bc1bc76bbce72285e26528 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 110 2.1E-23 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 162 1.1E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 SUPERFAMILY SSF88659 92 163 1.9E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 Pfam PF04542 Sigma-70 region 2 14 74 2.0E-4 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 Gene3D G3DSA:1.10.10.10 72 167 2.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 Gene3D G3DSA:1.10.1740.10 6 71 3.6E-5 T 28-03-2018 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 Pfam PF08281 Sigma-70, region 4 106 158 1.3E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS10935 3bb8f2eaef710ba170f738e7d3aa3a54 167 SUPERFAMILY SSF88946 11 88 1.29E-5 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Gene3D G3DSA:3.20.20.60 275 585 2.0E-88 T 28-03-2018 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 SUPERFAMILY SSF47831 41 160 2.75E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 1.2E-25 T 28-03-2018 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 483 498 1.2E-25 T 28-03-2018 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 519 531 1.2E-25 T 28-03-2018 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 313 332 1.2E-25 T 28-03-2018 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Gene3D G3DSA:1.10.274.10 41 155 8.5E-35 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 PIRSF PIRSF000732 15 584 1.4E-201 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 SUPERFAMILY SSF51621 269 560 7.85E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 271 557 1.1E-107 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 466 484 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Gene3D G3DSA:3.50.30.10 156 274 2.1E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 204 215 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 173 245 7.0E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 Pfam PF05524 PEP-utilising enzyme, N-terminal 20 143 2.2E-28 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 20 572 3.7E-165 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 AFA_RS08690 dd944efe312180c375faa337e7431ade 585 SUPERFAMILY SSF52009 142 266 2.35E-32 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFA_RS11510 2b01091e15b654e02e4be2b7015cfb3e 181 SUPERFAMILY SSF53271 9 176 1.97E-34 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS11510 2b01091e15b654e02e4be2b7015cfb3e 181 Pfam PF00156 Phosphoribosyl transferase domain 14 161 2.7E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFA_RS11510 2b01091e15b654e02e4be2b7015cfb3e 181 Gene3D G3DSA:3.40.50.2020 6 179 7.8E-24 T 28-03-2018 AFA_RS07430 7cf843749f515460d16316c05fdbb85e 204 SUPERFAMILY SSF159594 23 189 1.54E-21 T 28-03-2018 AFA_RS07430 7cf843749f515460d16316c05fdbb85e 204 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 184 1.9E-26 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component AFA_RS07430 7cf843749f515460d16316c05fdbb85e 204 Gene3D G3DSA:3.40.50.10610 14 195 2.1E-33 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component AFA_RS13230 eb2cb2968cb5a14aa5fe67d013d07798 237 Pfam PF00005 ABC transporter 21 162 1.4E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS13230 eb2cb2968cb5a14aa5fe67d013d07798 237 SUPERFAMILY SSF52540 5 231 4.02E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13230 eb2cb2968cb5a14aa5fe67d013d07798 237 Gene3D G3DSA:3.40.50.300 1 236 1.9E-35 T 28-03-2018 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 Pfam PF01047 MarR family 43 98 2.6E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 SMART SM00347 35 135 6.5E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 9.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 9.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 9.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 9.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 SUPERFAMILY SSF46785 11 147 4.08E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15930 804647438a60a402c676fda43a8b4e64 154 Gene3D G3DSA:1.10.10.10 1 154 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02180 770f17b2df6e8cc5db4c8267d53ac45f 409 Pfam PF02417 Chromate transporter 21 185 1.2E-30 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFA_RS02180 770f17b2df6e8cc5db4c8267d53ac45f 409 Pfam PF02417 Chromate transporter 237 401 3.5E-28 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFA_RS02180 770f17b2df6e8cc5db4c8267d53ac45f 409 TIGRFAM TIGR00937 2A51: chromate efflux transporter 27 401 9.0E-97 T 28-03-2018 IPR014047 Chromate transporter, long chain AFA_RS02180 770f17b2df6e8cc5db4c8267d53ac45f 409 PIRSF PIRSF004810 2 409 3.2E-119 T 28-03-2018 IPR014047 Chromate transporter, long chain AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 Gene3D G3DSA:1.20.58.340 140 256 2.2E-19 T 28-03-2018 AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 Gene3D G3DSA:1.20.58.340 265 334 1.8E-15 T 28-03-2018 AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 SUPERFAMILY SSF143865 7 259 2.75E-47 T 28-03-2018 AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 Pfam PF01544 CorA-like Mg2+ transporter protein 43 330 5.6E-51 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 Gene3D G3DSA:3.30.460.20 3 139 2.8E-19 T 28-03-2018 AFA_RS04710 9e866e3a89ef28b0dc6e4b3889180137 334 SUPERFAMILY SSF144083 270 331 9.55E-19 T 28-03-2018 AFA_RS09575 6bb3ea6b70f2e3bcf33209c44a56b2a9 108 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 33 106 1.2E-20 T 28-03-2018 IPR019110 Uncharacterised protein family, RAQPRD AFA_RS07170 dce05918ffe22c237921dcec146b6057 71 SUPERFAMILY SSF101756 10 70 6.28E-5 T 28-03-2018 IPR005220 Bacterial OB-fold AFA_RS06455 cab33cd13ea572b8bcaf4ec31e534b9c 459 Pfam PF00860 Permease family 38 419 3.7E-69 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 29 245 5.1E-58 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 SUPERFAMILY SSF53850 22 248 2.66E-66 T 28-03-2018 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 Gene3D G3DSA:3.40.190.10 199 248 3.0E-5 T 28-03-2018 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 PIRSF PIRSF004846 1 249 9.6E-72 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 Gene3D G3DSA:3.40.190.10 17 115 2.4E-18 T 28-03-2018 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 Gene3D G3DSA:3.40.190.10 116 198 2.0E-32 T 28-03-2018 AFA_RS04055 66c8fa20b9e9f79e88ac938b62cf8614 249 Pfam PF13531 Bacterial extracellular solute-binding protein 24 246 7.0E-51 T 28-03-2018 AFA_RS09065 fef1b6ff2ba0cbff0e1de0b6e1a2cee2 139 Gene3D G3DSA:2.60.40.1120 55 139 2.4E-4 T 28-03-2018 AFA_RS18560 9a67caefe4db8601e2f9e4171b148342 205 Pfam PF00857 Isochorismatase family 23 193 1.5E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS18560 9a67caefe4db8601e2f9e4171b148342 205 SUPERFAMILY SSF52499 18 200 1.7E-44 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS18560 9a67caefe4db8601e2f9e4171b148342 205 Gene3D G3DSA:3.40.50.850 1 203 1.8E-40 T 28-03-2018 AFA_RS05600 41270caf1803161c13f178a53e63dee2 127 SUPERFAMILY SSF161084 15 121 9.16E-23 T 28-03-2018 AFA_RS05600 41270caf1803161c13f178a53e63dee2 127 Pfam PF01124 MAPEG family 7 122 5.1E-21 T 28-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein AFA_RS05600 41270caf1803161c13f178a53e63dee2 127 Gene3D G3DSA:1.20.120.550 4 127 3.0E-17 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain AFA_RS17035 5b047c37c5a28670db1f9e6286cd77d7 446 SUPERFAMILY SSF53383 68 445 2.28E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS17035 5b047c37c5a28670db1f9e6286cd77d7 446 Gene3D G3DSA:3.90.1150.10 341 446 6.1E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS17035 5b047c37c5a28670db1f9e6286cd77d7 446 Pfam PF00155 Aminotransferase class I and II 96 439 6.4E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS17035 5b047c37c5a28670db1f9e6286cd77d7 446 Gene3D G3DSA:3.40.640.10 102 340 6.0E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS14695 b2b728f65e0df719ca3309623f3a4c42 211 Pfam PF01810 LysE type translocator 19 209 1.3E-44 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS14695 b2b728f65e0df719ca3309623f3a4c42 211 PIRSF PIRSF006324 4 211 4.4E-53 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS07850 3cdd3072b4a5808f9402ad0076472ae3 73 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 7 55 6.6E-16 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA AFA_RS07850 3cdd3072b4a5808f9402ad0076472ae3 73 SUPERFAMILY SSF46955 7 58 3.3E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS07850 3cdd3072b4a5808f9402ad0076472ae3 73 Gene3D G3DSA:1.10.10.10 8 67 9.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11150 32d9aeca07b025922fcb3378218e364d 168 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 136 4.7E-31 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AFA_RS03305 3cbd63b56034481ee71fd088879e3f89 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 173 1.2E-29 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS03305 3cbd63b56034481ee71fd088879e3f89 290 SUPERFAMILY SSF51735 1 283 8.27E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS03305 3cbd63b56034481ee71fd088879e3f89 290 Gene3D G3DSA:3.40.50.720 1 286 7.5E-46 T 28-03-2018 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 SMART SM00882 6 219 3.2E-75 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 219 1.4E-110 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 Gene3D G3DSA:3.40.1080.10 2 229 6.2E-78 T 28-03-2018 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 SUPERFAMILY SSF100950 2 222 1.5E-75 T 28-03-2018 AFA_RS08250 92332293242a11f1b12d9337a41a0698 231 Pfam PF01144 Coenzyme A transferase 8 218 8.0E-65 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 SUPERFAMILY SSF46785 10 89 1.45E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 Pfam PF03466 LysR substrate binding domain 99 302 8.2E-25 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 SUPERFAMILY SSF53850 94 303 1.14E-41 T 28-03-2018 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 70 1.6E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 4.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 4.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 4.9E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 Gene3D G3DSA:1.10.10.10 1 94 2.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 Gene3D G3DSA:3.40.190.10 190 276 8.0E-14 T 28-03-2018 AFA_RS02705 57a73834f296bc73c238011dc343c00f 318 Gene3D G3DSA:3.40.190.10 100 189 1.2E-16 T 28-03-2018 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 Gene3D G3DSA:3.30.465.10 94 214 6.6E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 468 1.6E-52 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 SUPERFAMILY SSF55103 218 471 1.59E-55 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 Gene3D G3DSA:1.10.45.10 429 468 1.7E-15 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 Pfam PF01565 FAD binding domain 38 176 8.2E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 SUPERFAMILY SSF56176 2 215 4.28E-76 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AFA_RS02750 a2298aaab4bcd74633f82bd33bd86cc5 471 Gene3D G3DSA:3.30.43.10 1 93 3.4E-26 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AFA_RS08330 9e010d11177a9817a5b40a4c31babf2f 88 Gene3D G3DSA:3.40.50.10320 25 88 2.5E-13 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 AFA_RS08330 9e010d11177a9817a5b40a4c31babf2f 88 Pfam PF02585 GlcNAc-PI de-N-acetylase 40 78 7.7E-6 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 Gene3D G3DSA:3.40.190.10 29 135 4.3E-23 T 28-03-2018 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 Pfam PF13531 Bacterial extracellular solute-binding protein 38 289 8.0E-45 T 28-03-2018 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 SUPERFAMILY SSF53850 29 336 1.2E-88 T 28-03-2018 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 21 335 3.6E-148 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 Gene3D G3DSA:3.40.190.10 136 253 6.4E-26 T 28-03-2018 AFA_RS11180 976fbd1379da6566c7e888cc9cb36605 339 Gene3D G3DSA:3.40.190.10 254 338 9.8E-23 T 28-03-2018 AFA_RS17575 3a5699aa9d2177de3a56a6d8ad237c44 857 Pfam PF00999 Sodium/hydrogen exchanger family 13 414 1.6E-58 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFA_RS17575 3a5699aa9d2177de3a56a6d8ad237c44 857 Gene3D G3DSA:2.60.120.10 672 820 2.5E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS17575 3a5699aa9d2177de3a56a6d8ad237c44 857 Pfam PF00027 Cyclic nucleotide-binding domain 740 800 1.2E-6 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain AFA_RS17575 3a5699aa9d2177de3a56a6d8ad237c44 857 SUPERFAMILY SSF51206 671 819 1.7E-16 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like AFA_RS16665 f734a839ba1e18cdc63623e386665630 108 PIRSF PIRSF005894 1 108 3.8E-47 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 AFA_RS16665 f734a839ba1e18cdc63623e386665630 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 3.5E-44 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related AFA_RS16665 f734a839ba1e18cdc63623e386665630 108 SUPERFAMILY SSF52833 1 106 4.74E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS16665 f734a839ba1e18cdc63623e386665630 108 Pfam PF00462 Glutaredoxin 17 82 7.6E-18 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFA_RS16665 f734a839ba1e18cdc63623e386665630 108 Gene3D G3DSA:3.40.30.10 2 108 7.3E-33 T 28-03-2018 AFA_RS12485 37e1b25b2b802a3db057a30e46ff9030 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 203 30.066 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 AFA_RS12485 37e1b25b2b802a3db057a30e46ff9030 208 SUPERFAMILY SSF52218 1 203 1.29E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS12485 37e1b25b2b802a3db057a30e46ff9030 208 Pfam PF02525 Flavodoxin-like fold 1 200 4.8E-47 T 28-03-2018 IPR003680 Flavodoxin-like fold AFA_RS12485 37e1b25b2b802a3db057a30e46ff9030 208 Gene3D G3DSA:3.40.50.360 1 208 1.8E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS04415 ac7481df73908d2640782cc377e3efa1 466 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 2 447 2.0E-90 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS04415 ac7481df73908d2640782cc377e3efa1 466 Pfam PF02321 Outer membrane efflux protein 264 445 2.4E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS04415 ac7481df73908d2640782cc377e3efa1 466 Pfam PF02321 Outer membrane efflux protein 55 240 1.2E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS04415 ac7481df73908d2640782cc377e3efa1 466 SUPERFAMILY SSF56954 23 449 3.27E-85 T 28-03-2018 AFA_RS04415 ac7481df73908d2640782cc377e3efa1 466 Gene3D G3DSA:1.20.1600.10 10 452 9.4E-81 T 28-03-2018 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 Gene3D G3DSA:3.30.420.140 4 135 8.6E-37 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 SMART SM00732 6 106 1.9E-27 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 6 133 20.91 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 9 130 5.2E-30 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 SUPERFAMILY SSF53098 6 132 1.52E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS15710 3d1595e832ff1fe823584da315c806af 135 Pfam PF03652 Holliday junction resolvase 7 131 1.9E-34 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFA_RS11175 864b062712d702405eedf9d062f36b7f 304 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 12 277 6.0E-95 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 AFA_RS11175 864b062712d702405eedf9d062f36b7f 304 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 19 280 1.8E-121 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 AFA_RS11175 864b062712d702405eedf9d062f36b7f 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 273 4.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11175 864b062712d702405eedf9d062f36b7f 304 SUPERFAMILY SSF161098 26 275 4.19E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS11175 864b062712d702405eedf9d062f36b7f 304 Gene3D G3DSA:1.10.3720.10 19 285 8.6E-45 T 28-03-2018 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 SMART SM00448 8 119 2.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 SMART SM00421 143 200 5.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 Pfam PF00072 Response regulator receiver domain 10 119 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 Gene3D G3DSA:3.40.50.2300 1 134 2.2E-34 T 28-03-2018 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 Gene3D G3DSA:1.10.10.10 135 204 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 SUPERFAMILY SSF46894 135 201 1.46E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 2.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 5.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 5.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 5.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS10280 a9ffe31ccbbc5aacda4f17818d634464 207 SUPERFAMILY SSF52172 8 157 8.25E-37 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 90 124 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 SMART SM00347 50 151 2.3E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 2.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 91 2.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 2.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 2.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 Pfam PF01047 MarR family 58 115 2.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 SUPERFAMILY SSF46785 24 161 5.55E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15745 37b7e5fbe12387d06576dfe87d9b2c79 176 Gene3D G3DSA:1.10.10.10 13 167 6.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 Gene3D G3DSA:3.40.50.150 105 304 8.5E-35 T 28-03-2018 AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 304 32.781 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 304 2.2E-85 T 28-03-2018 AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 298 6.4E-66 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 SUPERFAMILY SSF53335 54 300 2.09E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS15640 0e80bb0f979a3f50f977b56f3abe8d20 306 PIRSF PIRSF000401 1 305 1.4E-88 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFA_RS15195 d717de68150220a1b38dd58e2301c4c3 147 Gene3D G3DSA:3.30.420.10 1 146 2.9E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS15195 d717de68150220a1b38dd58e2301c4c3 147 Hamap MF_00042 Ribonuclease H [rnhA]. 2 147 32.298 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 AFA_RS15195 d717de68150220a1b38dd58e2301c4c3 147 Pfam PF00075 RNase H 5 141 1.3E-48 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFA_RS15195 d717de68150220a1b38dd58e2301c4c3 147 SUPERFAMILY SSF53098 3 142 1.64E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS18410 6e2117034f2ff98308639c4ba5fbb70d 271 SUPERFAMILY SSF52540 11 264 1.0E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS18410 6e2117034f2ff98308639c4ba5fbb70d 271 Pfam PF13614 AAA domain 13 186 7.3E-65 T 28-03-2018 IPR025669 AAA domain AFA_RS18410 6e2117034f2ff98308639c4ba5fbb70d 271 Gene3D G3DSA:3.40.50.300 10 270 1.2E-58 T 28-03-2018 AFA_RS17515 b68211330f78eb1f606b4c3a5914f131 275 Pfam PF15916 Domain of unknown function (DUF4743) 32 124 8.1E-6 T 28-03-2018 IPR031804 Domain of unknown function DUF4743 AFA_RS17515 b68211330f78eb1f606b4c3a5914f131 275 SUPERFAMILY SSF55811 109 263 2.57E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS17515 b68211330f78eb1f606b4c3a5914f131 275 Pfam PF00293 NUDIX domain 137 248 2.8E-10 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFA_RS17515 b68211330f78eb1f606b4c3a5914f131 275 Gene3D G3DSA:3.90.79.10 111 273 9.6E-21 T 28-03-2018 AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 Gene3D G3DSA:1.20.1250.20 17 232 1.6E-23 T 28-03-2018 AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 SUPERFAMILY SSF103473 19 438 4.05E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 Gene3D G3DSA:1.20.1250.20 247 446 8.8E-29 T 28-03-2018 AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 Pfam PF00083 Sugar (and other) transporter 26 441 6.4E-28 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS03330 2e1d6a403ff2b08c1a98bf3498a764b8 459 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS00035 8f4ce531db59e46b7700b7e9b07d12ba 485 Pfam PF00171 Aldehyde dehydrogenase family 26 477 1.4E-136 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS00035 8f4ce531db59e46b7700b7e9b07d12ba 485 Gene3D G3DSA:3.40.309.10 272 462 3.2E-59 T 28-03-2018 AFA_RS00035 8f4ce531db59e46b7700b7e9b07d12ba 485 SUPERFAMILY SSF53720 17 480 1.57E-129 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS00035 8f4ce531db59e46b7700b7e9b07d12ba 485 Gene3D G3DSA:3.40.605.10 10 271 2.4E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 Gene3D G3DSA:3.30.930.10 5 237 2.3E-45 T 28-03-2018 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 SUPERFAMILY SSF55681 20 235 2.98E-37 T 28-03-2018 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 SUPERFAMILY SSF50037 239 286 6.41E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 Pfam PF02237 Biotin protein ligase C terminal domain 239 286 1.1E-8 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 Gene3D G3DSA:2.30.30.100 239 287 9.1E-13 T 28-03-2018 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 Pfam PF03099 Biotin/lipoate A/B protein ligase family 62 169 9.2E-10 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 AFA_RS01215 c9660cbf2d0a62ff76cbe520f66667ce 289 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 29 284 1.4E-37 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 Gene3D G3DSA:3.90.380.10 138 382 5.4E-34 T 28-03-2018 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 Pfam PF00355 Rieske [2Fe-2S] domain 42 134 8.3E-9 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 Gene3D G3DSA:2.20.25.10 79 137 6.5E-16 T 28-03-2018 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 175 377 8.5E-34 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 SUPERFAMILY SSF50022 11 154 2.1E-26 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS03550 24c3a1f9a62ed1e78b417b8b97115e1e 382 SUPERFAMILY SSF55961 160 375 5.42E-44 T 28-03-2018 AFA_RS02835 b510de6addf7e95366baaf17b8f7648c 227 SUPERFAMILY SSF52964 49 146 1.57E-9 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AFA_RS02835 b510de6addf7e95366baaf17b8f7648c 227 Gene3D G3DSA:3.40.50.10070 40 183 3.9E-20 T 28-03-2018 AFA_RS02835 b510de6addf7e95366baaf17b8f7648c 227 Pfam PF03783 Curli production assembly/transport component CsgG 45 223 9.8E-35 T 28-03-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 AFA_RS00980 fad26c143804031469fe36944bc83dcf 115 Gene3D G3DSA:1.25.40.20 17 112 2.7E-22 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS00980 fad26c143804031469fe36944bc83dcf 115 SMART SM00248 85 115 140.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS00980 fad26c143804031469fe36944bc83dcf 115 SMART SM00248 52 81 7.3E-8 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS00980 fad26c143804031469fe36944bc83dcf 115 SUPERFAMILY SSF48403 28 111 2.02E-19 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS00980 fad26c143804031469fe36944bc83dcf 115 Pfam PF00023 Ankyrin repeat 52 83 7.3E-11 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS16340 0652781ebec774b681834345dfda62c1 216 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 14 198 19.55 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AFA_RS16340 0652781ebec774b681834345dfda62c1 216 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 49 197 2.9E-24 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AFA_RS16340 0652781ebec774b681834345dfda62c1 216 Gene3D G3DSA:2.60.450.10 46 195 1.4E-16 T 28-03-2018 AFA_RS16340 0652781ebec774b681834345dfda62c1 216 Pfam PF03968 OstA-like protein 57 174 3.9E-19 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 Pfam PF07690 Major Facilitator Superfamily 28 421 1.1E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 SUPERFAMILY SSF103473 25 213 6.8E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 SUPERFAMILY SSF103473 484 511 6.8E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 SUPERFAMILY SSF103473 260 431 6.8E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 Gene3D G3DSA:1.20.1250.20 263 522 6.6E-29 T 28-03-2018 AFA_RS12895 520da6aaa83aad168fe807ef09515590 522 Gene3D G3DSA:1.20.1250.20 21 213 1.6E-31 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Pfam PF13291 ACT domain 686 757 3.2E-11 T 28-03-2018 IPR002912 ACT domain AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Gene3D G3DSA:3.10.20.30 433 507 3.4E-20 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 51 757 6.0E-158 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Gene3D G3DSA:3.30.460.10 207 344 9.0E-44 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Pfam PF02824 TGS domain 439 497 2.8E-20 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 SUPERFAMILY SSF109604 15 210 9.1E-38 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Gene3D G3DSA:3.30.70.260 686 762 1.9E-9 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 SUPERFAMILY SSF81271 437 497 2.4E-18 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 SMART SM00954 254 364 1.2E-62 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 SUPERFAMILY SSF55021 687 757 1.04E-8 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 SUPERFAMILY SSF81301 211 389 2.94E-58 T 28-03-2018 AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Pfam PF13328 HD domain 37 195 8.2E-43 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS13195 65195cdd6864a0c8797e54e804c957c7 764 Pfam PF04607 Region found in RelA / SpoT proteins 254 363 7.9E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 SUPERFAMILY SSF52440 4 113 6.91E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS09520 5516b99200985b35694429ee80b12b34 400 Gene3D G3DSA:3.30.470.20 199 397 2.5E-39 T 28-03-2018 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 SUPERFAMILY SSF56059 114 320 6.19E-56 T 28-03-2018 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 SUPERFAMILY SSF51246 326 398 7.85E-18 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 398 6.5E-173 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 398 50.676 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 Gene3D G3DSA:3.30.1490.20 130 198 1.8E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS09520 5516b99200985b35694429ee80b12b34 400 Pfam PF02222 ATP-grasp domain 124 301 2.7E-52 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFA_RS09520 5516b99200985b35694429ee80b12b34 400 Gene3D G3DSA:3.40.50.20 2 123 7.3E-19 T 28-03-2018 AFA_RS08265 a16669720f868c96bd07cbc0b4cfc75a 91 SUPERFAMILY SSF54909 1 91 2.49E-38 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS08265 a16669720f868c96bd07cbc0b4cfc75a 91 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 2.0E-13 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 AFA_RS08265 a16669720f868c96bd07cbc0b4cfc75a 91 PIRSF PIRSF001486 1 91 1.3E-46 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 AFA_RS08265 a16669720f868c96bd07cbc0b4cfc75a 91 Pfam PF02426 Muconolactone delta-isomerase 1 89 2.3E-41 T 28-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 AFA_RS08265 a16669720f868c96bd07cbc0b4cfc75a 91 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 1.7E-46 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 AFA_RS01620 0eecb4ea4bc30eda223bdea8503b5239 221 Pfam PF01177 Asp/Glu/Hydantoin racemase 54 211 1.3E-10 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFA_RS01620 0eecb4ea4bc30eda223bdea8503b5239 221 Gene3D G3DSA:3.40.50.1860 115 205 8.3E-12 T 28-03-2018 AFA_RS01620 0eecb4ea4bc30eda223bdea8503b5239 221 Gene3D G3DSA:3.40.50.1860 13 114 1.9E-4 T 28-03-2018 AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 Gene3D G3DSA:3.40.50.720 2 136 2.2E-22 T 28-03-2018 AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 SUPERFAMILY SSF51735 3 133 2.41E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 SUPERFAMILY SSF116726 130 212 1.31E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 Gene3D G3DSA:3.30.70.1450 137 216 1.6E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 Pfam PF02080 TrkA-C domain 148 213 1.6E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS09025 d416aa1b964015c42b8812da02f4f0e3 217 Pfam PF02254 TrkA-N domain 4 119 1.5E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFA_RS16395 c699ce91eef27d4345552ab05f9e9f58 167 Pfam PF08534 Redoxin 29 153 2.2E-25 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFA_RS16395 c699ce91eef27d4345552ab05f9e9f58 167 SUPERFAMILY SSF52833 29 165 9.78E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS16395 c699ce91eef27d4345552ab05f9e9f58 167 Gene3D G3DSA:3.40.30.10 22 167 1.1E-32 T 28-03-2018 AFA_RS02515 e0f8b3c718451db0be048adee31e9113 261 SMART SM01007 32 210 3.1E-41 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02515 e0f8b3c718451db0be048adee31e9113 261 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 210 2.6E-36 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02515 e0f8b3c718451db0be048adee31e9113 261 Gene3D G3DSA:3.40.225.10 17 256 8.8E-47 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02515 e0f8b3c718451db0be048adee31e9113 261 SUPERFAMILY SSF53639 27 236 1.53E-53 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 1.5E-58 T 28-03-2018 IPR007551 Protein of unknown function DUF520 AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 Gene3D G3DSA:3.30.70.990 10 95 3.1E-26 T 28-03-2018 IPR035570 UPF0234 N-terminal domain AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 SUPERFAMILY SSF89963 90 161 2.88E-26 T 28-03-2018 IPR007551 Protein of unknown function DUF520 AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 Gene3D G3DSA:3.30.70.860 96 160 4.1E-29 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 SUPERFAMILY SSF89963 2 84 5.36E-27 T 28-03-2018 IPR007551 Protein of unknown function DUF520 AFA_RS10725 8d6d5be047b0e30997bc479bb7c7be54 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 26.992 T 28-03-2018 IPR007551 Protein of unknown function DUF520 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 SUPERFAMILY SSF46689 5 77 3.23E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 Gene3D G3DSA:3.40.50.10490 92 275 3.3E-14 T 28-03-2018 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 Pfam PF01380 SIS domain 127 250 7.7E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 71 1.7E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 SUPERFAMILY SSF53697 98 262 2.72E-13 T 28-03-2018 AFA_RS08890 d3f13d32e017d689b8367ac26e2de372 281 Gene3D G3DSA:1.10.10.10 2 77 3.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15715 12cd1b023e032391d1bbc3cc5365b7d0 196 Pfam PF02622 Uncharacterized ACR, COG1678 27 183 1.2E-44 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 AFA_RS15715 12cd1b023e032391d1bbc3cc5365b7d0 196 SUPERFAMILY SSF143456 16 196 3.27E-57 T 28-03-2018 AFA_RS15715 12cd1b023e032391d1bbc3cc5365b7d0 196 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 14 196 35.776 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 AFA_RS15715 12cd1b023e032391d1bbc3cc5365b7d0 196 Gene3D G3DSA:3.40.1740.10 133 186 8.1E-9 T 28-03-2018 AFA_RS15715 12cd1b023e032391d1bbc3cc5365b7d0 196 Gene3D G3DSA:3.30.70.1300 55 132 8.8E-28 T 28-03-2018 AFA_RS10045 6083d72a8a6703555222ae8a223f71ae 279 SUPERFAMILY SSF52218 90 262 5.43E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS10045 6083d72a8a6703555222ae8a223f71ae 279 Gene3D G3DSA:3.40.50.360 83 277 3.8E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS10045 6083d72a8a6703555222ae8a223f71ae 279 Pfam PF10982 Protein of unknown function (DUF2789) 4 76 5.3E-23 T 28-03-2018 IPR021250 Protein of unknown function DUF2789 AFA_RS10045 6083d72a8a6703555222ae8a223f71ae 279 Pfam PF03358 NADPH-dependent FMN reductase 90 234 5.5E-31 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS09790 e43585311c7a170eb0a45672124c5406 204 Pfam PF11679 Protein of unknown function (DUF3275) 2 201 2.8E-43 T 28-03-2018 IPR021693 Protein of unknown function DUF3275 AFA_RS13155 3874a2c9c0c77d9cc0dc239e384b0228 202 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 5 195 19.372 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 AFA_RS13155 3874a2c9c0c77d9cc0dc239e384b0228 202 Pfam PF01794 Ferric reductase like transmembrane component 49 161 7.7E-17 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain AFA_RS10660 456d12f9c947b484fd5caee48a6127bb 446 PIRSF PIRSF006066 165 446 2.6E-81 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS10660 456d12f9c947b484fd5caee48a6127bb 446 PIRSF PIRSF006066 4 167 5.8E-48 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS10660 456d12f9c947b484fd5caee48a6127bb 446 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 441 7.8E-115 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS10660 456d12f9c947b484fd5caee48a6127bb 446 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 435 1.8E-96 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 Pfam PF03023 MviN-like protein 28 470 2.1E-130 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 508 3.6E-137 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 473 19.741 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PIRSF PIRSF002869 1 517 5.0E-151 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 265 291 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 363 382 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 33 52 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 135 159 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 415 432 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 52 68 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS07340 2229243d013c8e7106341d9ee262ce61 517 PRINTS PR01806 Virulence factor MviN signature 159 180 2.2E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS12220 93daafe64b7acb4b691347c97c356909 247 SUPERFAMILY SSF52540 1 181 2.48E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12220 93daafe64b7acb4b691347c97c356909 247 Gene3D G3DSA:3.40.50.300 1 17 0.086 T 28-03-2018 AFA_RS12220 93daafe64b7acb4b691347c97c356909 247 Gene3D G3DSA:3.40.50.300 18 245 2.2E-6 T 28-03-2018 AFA_RS00745 8d3e0e091bbf0edfb62ff694b6a0a7d2 254 SUPERFAMILY SSF103032 11 249 2.35E-27 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 AFA_RS00745 8d3e0e091bbf0edfb62ff694b6a0a7d2 254 Pfam PF09234 Domain of unknown function (DUF1963) 45 253 2.7E-28 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 AFA_RS00745 8d3e0e091bbf0edfb62ff694b6a0a7d2 254 Gene3D G3DSA:2.30.320.10 7 254 1.9E-38 T 28-03-2018 AFA_RS02605 c57769cdc3d37f5d220c91f34b413df8 142 Pfam PF02566 OsmC-like protein 37 135 8.5E-18 T 28-03-2018 IPR003718 OsmC/Ohr family AFA_RS02605 c57769cdc3d37f5d220c91f34b413df8 142 SUPERFAMILY SSF82784 3 138 2.36E-38 T 28-03-2018 IPR003718 OsmC/Ohr family AFA_RS02605 c57769cdc3d37f5d220c91f34b413df8 142 Gene3D G3DSA:3.30.300.20 27 142 2.9E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS02605 c57769cdc3d37f5d220c91f34b413df8 142 Gene3D G3DSA:2.20.25.10 3 26 2.6E-12 T 28-03-2018 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 436 478 2.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Pfam PF13424 Tetratricopeptide repeat 477 543 7.4E-8 T 28-03-2018 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 505 589 2.4E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Pfam PF13432 Tetratricopeptide repeat 418 476 4.9E-5 T 28-03-2018 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Pfam PF14559 Tetratricopeptide repeat 268 324 1.4E-5 T 28-03-2018 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SUPERFAMILY SSF48452 417 578 8.13E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 53 148 0.0054 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 268 435 1.2E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 149 267 3.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 512 545 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 292 325 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 477 511 2.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 191 224 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 443 476 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SMART SM00028 546 578 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 Gene3D G3DSA:1.25.40.10 479 504 3.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS02790 091f5fec923f0d0ffef2e780993bffbe 593 SUPERFAMILY SSF48452 192 366 3.54E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS15840 82a689da693e079ca4b355d1040f20cd 223 SUPERFAMILY SSF52540 1 217 2.27E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15840 82a689da693e079ca4b355d1040f20cd 223 SMART SM00382 27 214 8.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15840 82a689da693e079ca4b355d1040f20cd 223 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS15840 82a689da693e079ca4b355d1040f20cd 223 Pfam PF00005 ABC transporter 18 166 1.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS15840 82a689da693e079ca4b355d1040f20cd 223 Gene3D G3DSA:3.40.50.300 1 219 1.2E-59 T 28-03-2018 AFA_RS12715 8fe45eb33eef82d51beba7f8fecf69ff 205 Pfam PF01467 Cytidylyltransferase-like 8 171 2.8E-28 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFA_RS12715 8fe45eb33eef82d51beba7f8fecf69ff 205 Gene3D G3DSA:3.40.50.620 2 198 4.9E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS12715 8fe45eb33eef82d51beba7f8fecf69ff 205 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 196 1.3E-52 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFA_RS12715 8fe45eb33eef82d51beba7f8fecf69ff 205 SUPERFAMILY SSF52374 3 196 9.48E-49 T 28-03-2018 AFA_RS12715 8fe45eb33eef82d51beba7f8fecf69ff 205 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 197 29.629 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 33 433 2.0E-175 T 28-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 Gene3D G3DSA:2.30.40.10 17 84 1.3E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 SUPERFAMILY SSF51556 77 379 3.44E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 Pfam PF01979 Amidohydrolase family 74 433 5.9E-60 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 Gene3D G3DSA:3.20.20.140 85 379 1.8E-67 T 28-03-2018 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 SUPERFAMILY SSF51338 379 401 7.35E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS11475 955b7d0a4387789f4f4f2d2e3d2b8daa 441 SUPERFAMILY SSF51338 44 78 7.35E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS14785 4d68fe9e1374643baeda2a42e1629a32 155 Pfam PF07080 Protein of unknown function (DUF1348) 8 137 6.4E-64 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 AFA_RS14785 4d68fe9e1374643baeda2a42e1629a32 155 Gene3D G3DSA:3.10.450.50 12 155 7.0E-68 T 28-03-2018 AFA_RS14785 4d68fe9e1374643baeda2a42e1629a32 155 SUPERFAMILY SSF54427 2 155 3.46E-78 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS01175 0776fadc6c6c829c1568304265421430 348 Gene3D G3DSA:3.40.190.10 148 278 1.7E-4 T 28-03-2018 AFA_RS01175 0776fadc6c6c829c1568304265421430 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 315 9.0E-31 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS01175 0776fadc6c6c829c1568304265421430 348 SUPERFAMILY SSF53850 113 218 1.27E-6 T 28-03-2018 AFA_RS16580 c65456bbd1857a333e42831d3eb938cd 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 287 7.4E-147 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFA_RS16580 c65456bbd1857a333e42831d3eb938cd 288 SUPERFAMILY SSF53448 2 286 2.93E-87 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16580 c65456bbd1857a333e42831d3eb938cd 288 Gene3D G3DSA:3.90.550.10 1 288 1.8E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS16580 c65456bbd1857a333e42831d3eb938cd 288 Pfam PF00483 Nucleotidyl transferase 2 237 9.9E-67 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFA_RS05345 0612b626e4a7956d2f979ce41d0b3b58 428 SUPERFAMILY SSF141868 164 396 3.92E-47 T 28-03-2018 IPR001633 EAL domain AFA_RS05345 0612b626e4a7956d2f979ce41d0b3b58 428 Gene3D G3DSA:3.20.20.450 143 395 4.4E-49 T 28-03-2018 IPR001633 EAL domain AFA_RS05345 0612b626e4a7956d2f979ce41d0b3b58 428 Pfam PF00563 EAL domain 162 390 1.9E-41 T 28-03-2018 IPR001633 EAL domain AFA_RS05345 0612b626e4a7956d2f979ce41d0b3b58 428 SMART SM00052 153 395 1.3E-25 T 28-03-2018 IPR001633 EAL domain AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 650 773 2.6E-25 T 28-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 2 227 1.2E-54 T 28-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 Gene3D G3DSA:1.10.3210.10 35 238 2.5E-6 T 28-03-2018 AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 SUPERFAMILY SSF46785 648 770 7.89E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 Gene3D G3DSA:2.40.10.200 667 772 1.9E-6 T 28-03-2018 AFA_RS09535 ee3a342fd84eb44c05e8870f0ffa5521 775 Pfam PF07514 Putative helicase 4 330 3.2E-96 T 28-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 SUPERFAMILY SSF52540 298 486 9.3E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 8 487 1.7E-177 T 28-03-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 Gene3D G3DSA:3.40.50.300 5 248 4.3E-53 T 28-03-2018 AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 Gene3D G3DSA:3.40.50.300 266 508 9.3E-80 T 28-03-2018 AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 271 488 1.8E-82 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 15 236 4.1E-40 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related AFA_RS09530 4d8cbf3eb715277fb6740850f491b07e 509 SUPERFAMILY SSF52540 46 234 3.23E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 PIRSF PIRSF002599 4 75 8.7E-11 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 SUPERFAMILY SSF50249 5 71 1.01E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 Pfam PF00313 'Cold-shock' DNA-binding domain 11 71 3.6E-13 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 Gene3D G3DSA:2.40.50.140 8 74 1.6E-15 T 28-03-2018 AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 SMART SM00357 10 72 1.0E-8 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 AFA_RS12350 2432a8ec3b5c34d7a39661959335c643 75 ProSitePatterns PS00352 'Cold-shock' domain signature. 22 40 - T 28-03-2018 IPR019844 Cold-shock conserved site AFA_RS11280 d7f206d5d7ca045b8554dfc357cc2a7e 411 PIRSF PIRSF001434 1 411 3.7E-110 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS11280 d7f206d5d7ca045b8554dfc357cc2a7e 411 Gene3D G3DSA:3.40.640.10 1 291 3.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS11280 d7f206d5d7ca045b8554dfc357cc2a7e 411 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 408 1.4E-98 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS11280 d7f206d5d7ca045b8554dfc357cc2a7e 411 Gene3D G3DSA:3.90.1150.10 292 411 6.5E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS11280 d7f206d5d7ca045b8554dfc357cc2a7e 411 SUPERFAMILY SSF53383 8 409 2.18E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS13515 c4d1678bed99f4a6231b3301a612a363 513 Pfam PF11954 Domain of unknown function (DUF3471) 408 502 2.0E-15 T 28-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal AFA_RS13515 c4d1678bed99f4a6231b3301a612a363 513 Pfam PF00144 Beta-lactamase 47 369 2.2E-60 T 28-03-2018 IPR001466 Beta-lactamase-related AFA_RS13515 c4d1678bed99f4a6231b3301a612a363 513 Gene3D G3DSA:3.40.710.10 44 373 2.0E-69 T 28-03-2018 AFA_RS13515 c4d1678bed99f4a6231b3301a612a363 513 SUPERFAMILY SSF56601 43 370 6.52E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS01030 1621e6f663826bfc22887bbef70b72b2 874 Pfam PF11874 Domain of unknown function (DUF3394) 676 865 5.9E-58 T 28-03-2018 IPR021814 Protein of unknown function DUF3394 AFA_RS01030 1621e6f663826bfc22887bbef70b72b2 874 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 139 671 1.6E-69 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS01030 1621e6f663826bfc22887bbef70b72b2 874 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 35 740 3.0E-231 T 28-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein AFA_RS13705 2116c48819a5be6eaac660e15e332386 65 Pfam PF04964 Flp/Fap pilin component 8 53 4.4E-20 T 28-03-2018 IPR007047 Flp/Fap pilin component AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 SUPERFAMILY SSF103473 23 433 1.31E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 84 100 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 Gene3D G3DSA:1.20.1250.20 232 434 3.9E-24 T 28-03-2018 AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 Gene3D G3DSA:1.20.1250.20 18 231 1.5E-27 T 28-03-2018 AFA_RS08435 4cbf16529ac85df39723110a7774c16d 434 Pfam PF07690 Major Facilitator Superfamily 33 384 5.1E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS17750 636f23aaeffc86002b8cb0c113f92144 249 Pfam PF13350 Tyrosine phosphatase family 13 248 1.1E-61 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type AFA_RS17750 636f23aaeffc86002b8cb0c113f92144 249 Gene3D G3DSA:3.90.190.10 28 190 1.1E-20 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like AFA_RS17750 636f23aaeffc86002b8cb0c113f92144 249 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 146 156 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 AFA_RS17750 636f23aaeffc86002b8cb0c113f92144 249 SUPERFAMILY SSF52799 13 247 6.78E-48 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like AFA_RS02275 41461f03b777a31a83b04cf9726449f0 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 293 9.2E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS02275 41461f03b777a31a83b04cf9726449f0 296 SUPERFAMILY SSF161098 58 282 6.28E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS02275 41461f03b777a31a83b04cf9726449f0 296 Gene3D G3DSA:1.10.3720.10 14 296 1.8E-45 T 28-03-2018 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 77 91 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 15 292 4.4E-81 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 SUPERFAMILY SSF54506 170 293 1.91E-44 T 28-03-2018 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 Pfam PF01678 Diaminopimelate epimerase 175 286 6.8E-25 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 Pfam PF01678 Diaminopimelate epimerase 16 135 8.5E-31 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 Gene3D G3DSA:3.10.310.10 4 136 1.7E-46 T 28-03-2018 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 Gene3D G3DSA:3.10.310.10 137 281 2.2E-45 T 28-03-2018 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 14 294 35.865 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFA_RS02005 1e711373282a55da9474112bbf5cd43b 307 SUPERFAMILY SSF54506 15 141 8.75E-40 T 28-03-2018 AFA_RS03080 ad5960cc934263872b2b3cf5eff2abd2 159 Pfam PF02391 MoaE protein 4 119 5.8E-36 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03080 ad5960cc934263872b2b3cf5eff2abd2 159 Gene3D G3DSA:3.90.1170.40 1 150 3.7E-54 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS03080 ad5960cc934263872b2b3cf5eff2abd2 159 SUPERFAMILY SSF54690 2 149 1.2E-49 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFA_RS10065 5ba6102a3ad2fa4e4a20468c4a95a6c5 269 Gene3D G3DSA:3.40.50.300 2 269 7.9E-16 T 28-03-2018 AFA_RS10065 5ba6102a3ad2fa4e4a20468c4a95a6c5 269 SUPERFAMILY SSF52540 4 32 1.22E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10065 5ba6102a3ad2fa4e4a20468c4a95a6c5 269 SUPERFAMILY SSF52540 155 258 1.22E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10065 5ba6102a3ad2fa4e4a20468c4a95a6c5 269 SUPERFAMILY SSF52540 84 117 1.22E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS10025 daa8d0c9a5cf30f56376f687fa88f9a3 190 Gene3D G3DSA:2.40.128.110 23 190 2.1E-45 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10025 daa8d0c9a5cf30f56376f687fa88f9a3 190 SUPERFAMILY SSF101874 24 188 6.02E-50 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10025 daa8d0c9a5cf30f56376f687fa88f9a3 190 Pfam PF04264 YceI-like domain 25 187 1.5E-36 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS10025 daa8d0c9a5cf30f56376f687fa88f9a3 190 SMART SM00867 24 188 2.5E-58 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFA_RS07270 758f1d2f729b662b1c38ad6a3312d294 268 SUPERFAMILY SSF161098 4 261 2.06E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07270 758f1d2f729b662b1c38ad6a3312d294 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 262 2.5E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07270 758f1d2f729b662b1c38ad6a3312d294 268 Gene3D G3DSA:1.10.3720.10 6 263 3.5E-37 T 28-03-2018 AFA_RS11405 8554e592e6ba42a8dce83a070c3c0b77 163 SUPERFAMILY SSF82784 4 150 7.46E-42 T 28-03-2018 IPR003718 OsmC/Ohr family AFA_RS11405 8554e592e6ba42a8dce83a070c3c0b77 163 Gene3D G3DSA:3.30.300.20 1 158 2.7E-42 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta AFA_RS11405 8554e592e6ba42a8dce83a070c3c0b77 163 Pfam PF02566 OsmC-like protein 50 150 1.0E-14 T 28-03-2018 IPR003718 OsmC/Ohr family AFA_RS15795 6eca1a3f3b5289de95b281ea8c170953 124 Pfam PF01381 Helix-turn-helix 8 61 4.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS15795 6eca1a3f3b5289de95b281ea8c170953 124 SMART SM00530 7 61 8.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS15795 6eca1a3f3b5289de95b281ea8c170953 124 SUPERFAMILY SSF47413 2 66 6.97E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS15795 6eca1a3f3b5289de95b281ea8c170953 124 Gene3D G3DSA:1.10.260.40 5 80 1.6E-18 T 28-03-2018 AFA_RS16465 283b8b8f010a24e8d7a58f8ccdac35c6 304 Gene3D G3DSA:3.40.50.150 31 280 1.6E-29 T 28-03-2018 AFA_RS16465 283b8b8f010a24e8d7a58f8ccdac35c6 304 SUPERFAMILY SSF53335 34 233 3.47E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS16465 283b8b8f010a24e8d7a58f8ccdac35c6 304 Pfam PF08241 Methyltransferase domain 53 160 4.3E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 Gene3D G3DSA:3.40.50.1970 7 171 5.1E-49 T 28-03-2018 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 Gene3D G3DSA:1.20.1090.10 172 359 7.1E-67 T 28-03-2018 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 PIRSF PIRSF001455 9 361 4.9E-109 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 7.4E-120 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 SUPERFAMILY SSF56796 11 353 5.89E-113 T 28-03-2018 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 41.232 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFA_RS17885 42ceea58fad6b650367142d7ca6057da 362 Pfam PF01761 3-dehydroquinate synthase 66 323 7.8E-108 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFA_RS02565 e220bfef5b403cdf50b28540ca31c10d 592 Gene3D G3DSA:2.40.160.50 230 592 4.8E-41 T 28-03-2018 AFA_RS02565 e220bfef5b403cdf50b28540ca31c10d 592 Pfam PF01103 Surface antigen 397 592 1.2E-23 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 AFA_RS02565 e220bfef5b403cdf50b28540ca31c10d 592 Gene3D G3DSA:3.10.20.310 108 197 3.1E-9 T 28-03-2018 AFA_RS02565 e220bfef5b403cdf50b28540ca31c10d 592 Pfam PF17243 POTRA domain TamA domain 1 33 103 1.1E-8 T 28-03-2018 IPR035243 TamA, POTRA domain 1 AFA_RS02990 2e4e58aca48950efd49c6e5805466911 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 2.7E-33 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS02990 2e4e58aca48950efd49c6e5805466911 150 Pfam PF02082 Transcriptional regulator 1 80 7.1E-25 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS02990 2e4e58aca48950efd49c6e5805466911 150 Gene3D G3DSA:1.10.10.10 1 139 3.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02990 2e4e58aca48950efd49c6e5805466911 150 SUPERFAMILY SSF46785 2 130 1.75E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 Gene3D G3DSA:2.40.128.130 776 1100 3.3E-34 T 28-03-2018 AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 SUPERFAMILY SSF51126 548 708 6.59E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 SUPERFAMILY SSF51126 333 509 6.59E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 Gene3D G3DSA:3.40.390.10 38 320 1.1E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 SMART SM00869 817 1089 3.7E-27 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 SUPERFAMILY SSF103515 789 1100 2.35E-40 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS18475 89ce7b3c828975948bcf14a82a80987f 1100 Pfam PF03797 Autotransporter beta-domain 821 1079 4.6E-36 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 143 167 2.9E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 66 88 2.9E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 180 199 2.9E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 200 219 2.9E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 35 56 2.9E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AFA_RS17025 da0c3f6500957037a681c0aa7c55f237 262 Pfam PF01061 ABC-2 type transporter 16 222 5.9E-18 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFA_RS03140 aada9539475a37f64269eb7a223797ab 140 Pfam PF03061 Thioesterase superfamily 19 104 1.7E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS03140 aada9539475a37f64269eb7a223797ab 140 SUPERFAMILY SSF54637 2 114 2.54E-29 T 28-03-2018 IPR029069 HotDog domain AFA_RS03140 aada9539475a37f64269eb7a223797ab 140 Gene3D G3DSA:3.10.129.10 1 137 2.4E-23 T 28-03-2018 AFA_RS09720 28573fe2792ea6068ba9dff35bd66908 868 SUPERFAMILY SSF52540 378 491 1.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09720 28573fe2792ea6068ba9dff35bd66908 868 SUPERFAMILY SSF52540 189 350 1.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09720 28573fe2792ea6068ba9dff35bd66908 868 Gene3D G3DSA:3.90.320.10 487 784 8.1E-13 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 AFA_RS09720 28573fe2792ea6068ba9dff35bd66908 868 Pfam PF12705 PD-(D/E)XK nuclease superfamily 566 810 7.8E-15 T 28-03-2018 AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 SUPERFAMILY SSF56112 15 226 2.73E-33 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 SMART SM00220 18 287 7.1E-11 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 Gene3D G3DSA:3.30.200.20 6 104 6.7E-12 T 28-03-2018 AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 Pfam PF00069 Protein kinase domain 19 225 1.2E-18 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFA_RS09665 d656413da4ae2e66917babe7d2b21a4b 567 Gene3D G3DSA:1.10.510.10 105 467 4.5E-21 T 28-03-2018 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 PIRSF PIRSF016578 159 415 9.5E-24 T 28-03-2018 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 PIRSF PIRSF016578 22 117 2.1E-10 T 28-03-2018 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 263 396 5.1E-21 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 SUPERFAMILY SSF47203 259 419 5.48E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 139 4.2E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 28 421 2.1E-175 T 28-03-2018 IPR023922 Sulphate-starvation-induced SfnB AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 Gene3D G3DSA:1.20.140.10 251 421 3.2E-21 T 28-03-2018 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 SUPERFAMILY SSF56645 40 244 5.76E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 Gene3D G3DSA:1.10.540.10 26 141 1.4E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS00495 28903bee4b4a09cc86dc8d520da12a17 421 Gene3D G3DSA:2.40.110.10 142 247 1.1E-13 T 28-03-2018 AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 SMART SM00939 315 571 3.0E-50 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 Gene3D G3DSA:3.40.50.1820 26 331 3.3E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 SUPERFAMILY SSF49785 398 549 8.29E-40 T 28-03-2018 IPR008979 Galactose-binding domain-like AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 SUPERFAMILY SSF49785 315 365 8.29E-40 T 28-03-2018 IPR008979 Galactose-binding domain-like AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 331 536 3.0E-36 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 47 531 4.4E-67 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 SUPERFAMILY SSF53474 41 362 2.11E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 50 297 6.8E-47 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFA_RS15560 00c4f2f5f7a73ff7776ebf71a4eac390 691 Gene3D G3DSA:2.60.120.260 332 562 1.6E-42 T 28-03-2018 IPR008979 Galactose-binding domain-like AFA_RS05570 654fcae565e1b545eb361132e6b0e20a 120 Gene3D G3DSA:1.10.760.10 36 114 1.3E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS05570 654fcae565e1b545eb361132e6b0e20a 120 SUPERFAMILY SSF46626 44 108 1.89E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS05570 654fcae565e1b545eb361132e6b0e20a 120 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 42 106 8.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 Gene3D G3DSA:2.30.30.60 647 696 1.8E-13 T 28-03-2018 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 Pfam PF12607 Protein of unknown function (DUF3772) 136 194 7.3E-15 T 28-03-2018 IPR022249 Domain of unknown function DUF3772 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 SUPERFAMILY SSF82861 545 628 5.23E-12 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 Pfam PF00924 Mechanosensitive ion channel 587 785 2.9E-45 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 Gene3D G3DSA:3.30.70.100 700 790 8.6E-14 T 28-03-2018 AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 SUPERFAMILY SSF50182 630 695 6.21E-16 T 28-03-2018 IPR010920 LSM domain AFA_RS06580 425f1ac55b89235fff88c1c03bca61a6 813 SUPERFAMILY SSF82689 697 785 6.28E-13 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 Gene3D G3DSA:1.20.1600.10 34 495 9.2E-78 T 28-03-2018 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 29 493 3.0E-107 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 Pfam PF02321 Outer membrane efflux protein 92 283 5.1E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 Pfam PF02321 Outer membrane efflux protein 314 491 2.1E-22 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 SUPERFAMILY SSF56954 83 493 4.58E-88 T 28-03-2018 AFA_RS12315 b7a6946ec8ab6342d459631feffb373c 495 SUPERFAMILY SSF56954 15 46 4.58E-88 T 28-03-2018 AFA_RS04785 147a722c68aeb72d53c82c0e68bfaf0f 210 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 160 1.8E-21 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS14685 319f0042c902bd9a1dad0b732f579a94 63 Pfam PF01679 Proteolipid membrane potential modulator 1 47 2.7E-7 T 28-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 497 86.924 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 Gene3D G3DSA:3.90.1300.10 6 505 3.9E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 SUPERFAMILY SSF75304 7 503 1.11E-148 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 Pfam PF01425 Amidase 29 486 5.5E-141 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 ProSitePatterns PS00571 Amidases signature. 152 183 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFA_RS15885 0e16b01cd4a2cd0cd8b208952467a544 506 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 497 7.7E-160 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 SUPERFAMILY SSF53850 29 367 1.13E-92 T 28-03-2018 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 Pfam PF13416 Bacterial extracellular solute-binding protein 48 333 2.1E-31 T 28-03-2018 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 157 171 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 180 199 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 267 286 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 312 338 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 126 142 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 217 236 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 1.2E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 Gene3D G3DSA:3.40.190.10 23 206 2.3E-31 T 28-03-2018 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 PIRSF PIRSF019574 4 368 2.5E-134 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFA_RS05310 5e7f416184dc49d3bd9a132ba6a24636 368 Gene3D G3DSA:3.40.190.10 207 334 1.1E-18 T 28-03-2018 AFA_RS12050 655a261b09a20564a6137b52a601fec5 374 Gene3D G3DSA:3.60.21.10 145 371 3.3E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS12050 655a261b09a20564a6137b52a601fec5 374 SUPERFAMILY SSF56300 143 372 3.07E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS12050 655a261b09a20564a6137b52a601fec5 374 Pfam PF00149 Calcineurin-like phosphoesterase 148 314 6.5E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 SUPERFAMILY SSF102886 7 301 1.11E-130 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 2 277 51.358 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 166 190 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 Pfam PF01218 Coproporphyrinogen III oxidase 8 301 2.0E-127 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PIRSF PIRSF000166 3 301 1.1E-122 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 234 261 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 88 112 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 29 45 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 162 191 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 125 147 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 262 288 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 PRINTS PR00073 Coprogen oxidase signature 46 67 5.2E-79 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS12710 16f446a257ed6e782db05382ad121675 301 Gene3D G3DSA:3.40.1500.10 4 301 1.2E-134 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 387 396 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 181 396 1.0E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 SUPERFAMILY SSF52540 128 402 1.37E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 Gene3D G3DSA:3.40.50.300 127 402 8.2E-82 T 28-03-2018 AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 SMART SM00382 193 380 9.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 20 476 5.1E-176 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS05945 6d2cf7632c7c6c9182245ca092047825 480 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 34 474 1.2E-195 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 SUPERFAMILY SSF82057 44 114 2.01E-20 T 28-03-2018 AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 Gene3D G3DSA:2.20.25.10 2 40 2.1E-11 T 28-03-2018 AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 6 114 2.5E-41 T 28-03-2018 IPR004624 PhnA protein AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 Gene3D G3DSA:2.30.30.40 48 113 3.1E-26 T 28-03-2018 AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 Pfam PF08274 PhnA Zinc-Ribbon 6 32 1.9E-9 T 28-03-2018 IPR013987 PhnA protein, N-terminal AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 Pfam PF03831 PhnA domain 49 114 1.5E-24 T 28-03-2018 IPR013988 PhnA protein, C-terminal AFA_RS06130 2dd183c72afa50ee836f7e33d6dfc34a 114 SUPERFAMILY SSF57783 6 35 6.56E-10 T 28-03-2018 AFA_RS03120 7dfa194be039f6f90155e57948b931e6 169 Gene3D G3DSA:3.40.30.10 1 167 2.3E-25 T 28-03-2018 AFA_RS03120 7dfa194be039f6f90155e57948b931e6 169 SUPERFAMILY SSF52833 1 166 8.8E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS03120 7dfa194be039f6f90155e57948b931e6 169 Pfam PF08534 Redoxin 5 164 1.5E-33 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFA_RS04800 fb826894799d44f19be807641522c3f5 91 Pfam PF14542 GCN5-related N-acetyl-transferase 14 89 3.0E-25 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFA_RS04800 fb826894799d44f19be807641522c3f5 91 Gene3D G3DSA:3.40.630.30 1 91 1.0E-16 T 28-03-2018 AFA_RS04800 fb826894799d44f19be807641522c3f5 91 SUPERFAMILY SSF55729 4 90 4.37E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS02510 96c802f55eff0ba52cb539cca68dd5fa 442 Gene3D G3DSA:1.20.1250.20 11 230 1.2E-20 T 28-03-2018 AFA_RS02510 96c802f55eff0ba52cb539cca68dd5fa 442 SUPERFAMILY SSF103473 20 427 2.49E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS02510 96c802f55eff0ba52cb539cca68dd5fa 442 Gene3D G3DSA:1.20.1250.20 234 439 9.0E-19 T 28-03-2018 AFA_RS02510 96c802f55eff0ba52cb539cca68dd5fa 442 Pfam PF00083 Sugar (and other) transporter 21 226 5.3E-23 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFA_RS13235 f9e24af778829e26f600e0fb31b4e928 213 Gene3D G3DSA:2.40.160.20 31 213 3.5E-37 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS13235 f9e24af778829e26f600e0fb31b4e928 213 Pfam PF03922 OmpW family 32 213 2.0E-57 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 AFA_RS13235 f9e24af778829e26f600e0fb31b4e928 213 SUPERFAMILY SSF56925 32 213 7.32E-32 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS09110 3eba4350260e2bf4deaeadd50ede1db3 479 Pfam PF00474 Sodium:solute symporter family 37 411 1.0E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS16975 16c289d774884266b8e3b70a25dabe86 438 Gene3D G3DSA:3.40.50.2000 248 422 3.0E-29 T 28-03-2018 AFA_RS16975 16c289d774884266b8e3b70a25dabe86 438 Pfam PF13579 Glycosyl transferase 4-like domain 60 238 1.6E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS16975 16c289d774884266b8e3b70a25dabe86 438 Pfam PF13692 Glycosyl transferases group 1 256 398 2.1E-20 T 28-03-2018 AFA_RS16975 16c289d774884266b8e3b70a25dabe86 438 SUPERFAMILY SSF53756 55 427 4.54E-58 T 28-03-2018 AFA_RS16975 16c289d774884266b8e3b70a25dabe86 438 Gene3D G3DSA:3.40.50.2000 54 247 2.9E-19 T 28-03-2018 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 Gene3D G3DSA:3.40.640.10 136 343 4.3E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 Gene3D G3DSA:1.10.10.10 2 64 3.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 Gene3D G3DSA:3.90.1150.10 344 441 7.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 Pfam PF00155 Aminotransferase class I and II 96 439 1.4E-39 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 62 2.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 SUPERFAMILY SSF53383 89 439 8.86E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 SMART SM00345 3 62 3.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS13975 3eff4aa798096aeabe36192493cbfcf7 445 SUPERFAMILY SSF46785 4 66 1.01E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07255 0b81231931ace6350bc7d87ff4d7d8ac 277 Gene3D G3DSA:3.60.21.10 5 263 2.4E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07255 0b81231931ace6350bc7d87ff4d7d8ac 277 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 4 259 37.41 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AFA_RS07255 0b81231931ace6350bc7d87ff4d7d8ac 277 SUPERFAMILY SSF56300 6 262 3.21E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07255 0b81231931ace6350bc7d87ff4d7d8ac 277 Pfam PF00149 Calcineurin-like phosphoesterase 7 201 7.5E-21 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 SMART SM00387 513 625 5.3E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 Pfam PF05226 CHASE2 domain 5 284 9.4E-49 T 28-03-2018 IPR007890 CHASE2 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 SUPERFAMILY SSF55874 460 621 3.8E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 Gene3D G3DSA:3.30.565.10 464 623 9.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 578 5.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 603 5.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 622 5.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 564 5.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 SUPERFAMILY SSF47384 392 469 5.69E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 515 621 1.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 Gene3D G3DSA:1.10.287.130 396 463 3.3E-6 T 28-03-2018 AFA_RS18320 4195b93d43687ff31e9a433c11ece763 630 SMART SM01080 18 293 3.1E-67 T 28-03-2018 IPR007890 CHASE2 AFA_RS09215 e8a24ae8de226b478feb8a9325523e05 507 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 349 369 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS09215 e8a24ae8de226b478feb8a9325523e05 507 Pfam PF00860 Permease family 24 401 5.4E-87 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS09215 e8a24ae8de226b478feb8a9325523e05 507 TIGRFAM TIGR03173 pbuX: xanthine permease 26 434 5.3E-151 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 AFA_RS09215 e8a24ae8de226b478feb8a9325523e05 507 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 24 432 4.9E-99 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFA_RS17385 691fba08dc96911b9433451e0129cfc4 274 Gene3D G3DSA:3.60.110.10 1 274 2.8E-80 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS17385 691fba08dc96911b9433451e0129cfc4 274 SUPERFAMILY SSF56317 1 265 3.79E-78 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS17385 691fba08dc96911b9433451e0129cfc4 274 Pfam PF00795 Carbon-nitrogen hydrolase 5 256 3.0E-54 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 SMART SM00382 49 241 9.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 Pfam PF00005 ABC transporter 41 192 1.0E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 SUPERFAMILY SSF52540 29 263 1.59E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 Gene3D G3DSA:3.40.50.300 6 334 2.7E-82 T 28-03-2018 AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 325 1.3E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 2.7E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFA_RS00410 70b239d63da5bd4ccce61d767cd1355a 334 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS13915 2af4c0fd118e828558a00f95e7b36b87 106 Pfam PF00355 Rieske [2Fe-2S] domain 5 90 3.9E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS13915 2af4c0fd118e828558a00f95e7b36b87 106 SUPERFAMILY SSF50022 1 103 3.01E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS13915 2af4c0fd118e828558a00f95e7b36b87 106 Gene3D G3DSA:2.102.10.10 3 106 3.3E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00490 4a5e45072fd02d5368758507cdf612cd 220 SUPERFAMILY SSF161098 11 204 5.89E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00490 4a5e45072fd02d5368758507cdf612cd 220 Gene3D G3DSA:1.10.3720.10 8 220 8.4E-39 T 28-03-2018 AFA_RS00490 4a5e45072fd02d5368758507cdf612cd 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 217 6.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 SUPERFAMILY SSF48498 87 198 5.48E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 Gene3D G3DSA:1.10.357.10 68 203 1.3E-11 T 28-03-2018 AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 Gene3D G3DSA:1.10.10.60 2 67 2.9E-13 T 28-03-2018 AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 SUPERFAMILY SSF46689 10 92 3.18E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS03160 ab6257d63f845b017133bd030f7d2e1d 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 7.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS02085 0c918709e37ab19ede59e9177e9cf28b 161 SUPERFAMILY SSF51182 25 134 4.72E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS02085 0c918709e37ab19ede59e9177e9cf28b 161 Gene3D G3DSA:2.60.120.10 13 147 3.3E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS02085 0c918709e37ab19ede59e9177e9cf28b 161 Pfam PF12973 ChrR Cupin-like domain 60 130 1.4E-6 T 28-03-2018 IPR025979 ChrR-like cupin domain AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 PIRSF PIRSF002191 2 124 4.3E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 117 3.4E-46 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.623 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 SUPERFAMILY SSF50104 10 118 2.01E-42 T 28-03-2018 IPR008991 Translation protein SH3-like domain AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 Pfam PF01245 Ribosomal protein L19 18 117 4.1E-45 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 PRINTS PR00061 Ribosomal protein L19 signature 92 117 3.6E-32 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 PRINTS PR00061 Ribosomal protein L19 signature 38 67 3.6E-32 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11880 6afff49204a9c42bdd2a69cc924a4571 124 PRINTS PR00061 Ribosomal protein L19 signature 8 37 3.6E-32 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05320 b5dc28968cfd0546f398f974805b5df3 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 288 1.9E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05320 b5dc28968cfd0546f398f974805b5df3 305 SUPERFAMILY SSF161098 14 292 3.55E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS05320 b5dc28968cfd0546f398f974805b5df3 305 Gene3D G3DSA:1.10.3720.10 14 303 5.6E-42 T 28-03-2018 AFA_RS03780 cabac2c5c0630408d827631a69db41f2 259 SUPERFAMILY SSF161098 66 242 2.09E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS03780 cabac2c5c0630408d827631a69db41f2 259 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 65 151 5.5E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS03780 cabac2c5c0630408d827631a69db41f2 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 257 5.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS03780 cabac2c5c0630408d827631a69db41f2 259 Gene3D G3DSA:1.10.3720.10 60 257 3.4E-30 T 28-03-2018 AFA_RS08170 25d11e059e80de3e7d0823af515a5fe1 90 Gene3D G3DSA:3.10.20.30 1 90 7.9E-18 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS08170 25d11e059e80de3e7d0823af515a5fe1 90 SUPERFAMILY SSF54285 1 90 3.92E-20 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFA_RS08170 25d11e059e80de3e7d0823af515a5fe1 90 Pfam PF02597 ThiS family 5 90 2.4E-17 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 SUPERFAMILY SSF51246 331 443 1.99E-43 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 5.0E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Gene3D G3DSA:3.40.50.20 1 123 9.4E-53 T 28-03-2018 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 SUPERFAMILY SSF52440 1 113 2.01E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.6E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 SUPERFAMILY SSF56059 83 345 1.94E-66 T 28-03-2018 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Gene3D G3DSA:3.30.470.20 211 444 2.9E-95 T 28-03-2018 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 SMART SM00878 336 441 5.1E-66 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 7.7E-221 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.4E-39 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFA_RS15645 da8482e4aa0b796db3a32a2b9afab9a1 449 Gene3D G3DSA:3.30.1490.20 124 210 1.9E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 SUPERFAMILY SSF52166 1 206 1.3E-69 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.986 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 Gene3D G3DSA:3.40.1370.10 1 144 7.2E-46 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 Gene3D G3DSA:3.40.1370.10 145 204 5.1E-10 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 203 2.1E-68 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18265 89b446ad09c7fda54df134facfda797a 206 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 3.3E-60 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 Gene3D G3DSA:3.40.1410.10 123 244 6.0E-17 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 SUPERFAMILY SSF46785 11 82 2.01E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 SMART SM00866 101 239 2.4E-6 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 SMART SM00345 21 80 4.3E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 Gene3D G3DSA:1.10.10.10 4 81 8.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 SUPERFAMILY SSF64288 68 244 8.32E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.5E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS15040 31e1f95ec98427c54689fb12b474fd1d 248 Pfam PF07702 UTRA domain 131 237 5.4E-12 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS13580 f14b5a9dd25cb9292fc4f6aa12a442bf 101 Pfam PF07876 Stress responsive A/B Barrel Domain 4 94 6.3E-12 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel AFA_RS13580 f14b5a9dd25cb9292fc4f6aa12a442bf 101 SUPERFAMILY SSF54909 1 94 1.04E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS13580 f14b5a9dd25cb9292fc4f6aa12a442bf 101 Gene3D G3DSA:3.30.70.100 1 99 4.7E-17 T 28-03-2018 AFA_RS13580 f14b5a9dd25cb9292fc4f6aa12a442bf 101 SMART SM00886 2 96 6.2E-13 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel AFA_RS15880 a6e4897471b8d0fc53c4c90d1f5dabdd 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 97 2.6E-18 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFA_RS15880 a6e4897471b8d0fc53c4c90d1f5dabdd 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 102 20.421 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFA_RS15880 a6e4897471b8d0fc53c4c90d1f5dabdd 102 SUPERFAMILY SSF141000 2 100 1.44E-22 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFA_RS15880 a6e4897471b8d0fc53c4c90d1f5dabdd 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 102 4.7E-25 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFA_RS09940 a12deb6f2fcc6714bf5ed1de68b45b41 342 Pfam PF06996 Type VI secretion, TssG 24 313 1.4E-79 T 28-03-2018 IPR010732 Type VI secretion, TssG-like AFA_RS09940 a12deb6f2fcc6714bf5ed1de68b45b41 342 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 24 313 5.0E-80 T 28-03-2018 IPR010732 Type VI secretion, TssG-like AFA_RS16780 bbc26aa4fb0d37858c7461c2558dd217 222 SUPERFAMILY SSF47413 143 207 3.75E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS16780 bbc26aa4fb0d37858c7461c2558dd217 222 Pfam PF13560 Helix-turn-helix domain 152 208 4.7E-8 T 28-03-2018 AFA_RS16780 bbc26aa4fb0d37858c7461c2558dd217 222 SMART SM00530 152 207 1.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS16780 bbc26aa4fb0d37858c7461c2558dd217 222 Gene3D G3DSA:1.10.260.40 142 212 2.5E-8 T 28-03-2018 AFA_RS04735 ef75103c587099b5de7eff9b9d998308 484 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 265 470 1.1E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04735 ef75103c587099b5de7eff9b9d998308 484 SUPERFAMILY SSF161098 248 447 9.42E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS04735 ef75103c587099b5de7eff9b9d998308 484 Gene3D G3DSA:1.10.3720.10 143 458 1.7E-35 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Pfam PF07499 RuvA, C-terminal domain 149 191 4.4E-13 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Gene3D G3DSA:1.10.8.10 145 193 1.8E-12 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 SUPERFAMILY SSF46929 147 192 2.22E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 SUPERFAMILY SSF50249 1 63 1.37E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 30.931 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 SUPERFAMILY SSF47781 65 133 2.61E-20 T 28-03-2018 IPR010994 RuvA domain 2-like AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Gene3D G3DSA:2.40.50.140 1 66 7.4E-25 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Gene3D G3DSA:1.10.150.20 67 118 1.8E-15 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Gene3D G3DSA:1.10.150.20 119 144 0.011 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 SMART SM00278 73 92 23.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 SMART SM00278 108 127 0.0028 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Pfam PF01330 RuvA N terminal domain 1 62 1.1E-21 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 Pfam PF14520 Helix-hairpin-helix domain 72 129 4.3E-17 T 28-03-2018 AFA_RS14445 6c1f84e06c7cf6a499f73a52eacaed3a 193 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 190 1.6E-57 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFA_RS15360 434aded47851604ff3c4a812051526c6 273 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 239 3.3E-93 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 AFA_RS15360 434aded47851604ff3c4a812051526c6 273 Pfam PF00005 ABC transporter 19 171 4.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS15360 434aded47851604ff3c4a812051526c6 273 Gene3D G3DSA:3.40.50.300 1 239 2.2E-58 T 28-03-2018 AFA_RS15360 434aded47851604ff3c4a812051526c6 273 SMART SM00382 26 228 6.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15360 434aded47851604ff3c4a812051526c6 273 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS15360 434aded47851604ff3c4a812051526c6 273 SUPERFAMILY SSF52540 2 231 1.93E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS06895 0ae36eba9fdc44258ea04e7f3f319763 122 Gene3D G3DSA:1.20.5.620 46 104 2.5E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain AFA_RS06895 0ae36eba9fdc44258ea04e7f3f319763 122 SUPERFAMILY SSF81573 47 102 1.57E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain AFA_RS13000 636c36cd6d147ef3b7186c3409cfa35a 268 Gene3D G3DSA:3.40.50.300 1 242 4.5E-54 T 28-03-2018 AFA_RS13000 636c36cd6d147ef3b7186c3409cfa35a 268 Pfam PF00005 ABC transporter 27 164 7.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS13000 636c36cd6d147ef3b7186c3409cfa35a 268 SUPERFAMILY SSF52540 3 226 2.81E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13000 636c36cd6d147ef3b7186c3409cfa35a 268 SMART SM00382 29 214 2.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13000 636c36cd6d147ef3b7186c3409cfa35a 268 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS09270 c8ee666f00e33c670dd8be05ad898cc3 310 Pfam PF03755 YicC-like family, N-terminal region 2 152 2.3E-33 T 28-03-2018 IPR013527 YicC-like, N-terminal AFA_RS09270 c8ee666f00e33c670dd8be05ad898cc3 310 Pfam PF08340 Domain of unknown function (DUF1732) 214 310 4.7E-31 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 AFA_RS09270 c8ee666f00e33c670dd8be05ad898cc3 310 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 310 3.1E-56 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 AFA_RS17180 722d7df9db73e525e89845f8630c0a7c 77 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 75 22.958 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFA_RS17180 722d7df9db73e525e89845f8630c0a7c 77 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 2.3E-23 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFA_RS17180 722d7df9db73e525e89845f8630c0a7c 77 Pfam PF02416 mttA/Hcf106 family 5 54 2.3E-14 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFA_RS07610 47ea58bf5355f61d343a09c4ff2a9bb0 132 SUPERFAMILY SSF58100 66 128 3.92E-5 T 28-03-2018 AFA_RS07610 47ea58bf5355f61d343a09c4ff2a9bb0 132 Gene3D G3DSA:1.20.1170.10 24 132 9.9E-5 T 28-03-2018 AFA_RS07610 47ea58bf5355f61d343a09c4ff2a9bb0 132 Pfam PF06476 Protein of unknown function (DUF1090) 15 118 4.7E-27 T 28-03-2018 IPR009468 Protein of unknown function DUF1090 AFA_RS12615 6c1d58e74fc510e031e522020769352e 307 SUPERFAMILY SSF51197 30 291 9.06E-63 T 28-03-2018 AFA_RS12615 6c1d58e74fc510e031e522020769352e 307 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 21 295 1.9E-131 T 28-03-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 AFA_RS12615 6c1d58e74fc510e031e522020769352e 307 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 45 260 2.7E-34 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase AFA_RS12615 6c1d58e74fc510e031e522020769352e 307 Gene3D G3DSA:2.60.120.620 30 273 2.9E-44 T 28-03-2018 AFA_RS04385 458593e62eb0ea3e56cd8b144fb11489 396 SMART SM00558 91 224 3.5E-4 T 28-03-2018 IPR003347 JmjC domain AFA_RS04385 458593e62eb0ea3e56cd8b144fb11489 396 Pfam PF08007 Cupin superfamily protein 16 300 1.9E-82 T 28-03-2018 IPR003347 JmjC domain AFA_RS04385 458593e62eb0ea3e56cd8b144fb11489 396 Gene3D G3DSA:2.60.120.650 7 211 3.0E-32 T 28-03-2018 AFA_RS04385 458593e62eb0ea3e56cd8b144fb11489 396 SUPERFAMILY SSF51197 6 314 3.3E-66 T 28-03-2018 AFA_RS07375 ed987e4e6c29822727fa7d73b8ee13a5 201 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 185 1.6E-27 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AFA_RS01835 a632947a4e01371f809c911506d12377 209 SUPERFAMILY SSF53335 18 200 1.08E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS01835 a632947a4e01371f809c911506d12377 209 Gene3D G3DSA:3.40.50.150 10 205 5.6E-19 T 28-03-2018 AFA_RS01835 a632947a4e01371f809c911506d12377 209 Pfam PF07021 Methionine biosynthesis protein MetW 14 200 5.3E-73 T 28-03-2018 IPR010743 Methionine biosynthesis MetW AFA_RS01835 a632947a4e01371f809c911506d12377 209 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 14 201 5.2E-83 T 28-03-2018 IPR010743 Methionine biosynthesis MetW AFA_RS03350 0c4cbd35240b0f57cdc57ad14d400f3c 279 Gene3D G3DSA:1.10.530.10 65 269 2.3E-20 T 28-03-2018 AFA_RS03350 0c4cbd35240b0f57cdc57ad14d400f3c 279 Pfam PF01464 Transglycosylase SLT domain 160 246 4.8E-15 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS03350 0c4cbd35240b0f57cdc57ad14d400f3c 279 SUPERFAMILY SSF53955 159 269 4.3E-21 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS12690 3a86c350bf497d9e39d7168c160d2977 312 Gene3D G3DSA:3.40.50.720 5 125 9.2E-12 T 28-03-2018 AFA_RS12690 3a86c350bf497d9e39d7168c160d2977 312 Gene3D G3DSA:3.40.50.720 126 278 8.0E-37 T 28-03-2018 AFA_RS12690 3a86c350bf497d9e39d7168c160d2977 312 SUPERFAMILY SSF51735 97 278 1.68E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS12690 3a86c350bf497d9e39d7168c160d2977 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 277 3.4E-43 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFA_RS12690 3a86c350bf497d9e39d7168c160d2977 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216 232 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 Pfam PF07661 MORN repeat variant 184 203 0.026 T 28-03-2018 IPR011652 MORN variant AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 Pfam PF07661 MORN repeat variant 159 180 3.0E-5 T 28-03-2018 IPR011652 MORN variant AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 SUPERFAMILY SSF82185 251 302 8.63E-5 T 28-03-2018 AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 Gene3D G3DSA:2.20.110.10 64 182 8.0E-10 T 28-03-2018 AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 Gene3D G3DSA:2.20.110.10 183 306 5.1E-13 T 28-03-2018 AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 SUPERFAMILY SSF82185 71 157 1.09E-8 T 28-03-2018 AFA_RS08870 cdd2a847ce737e50983fefacd2e3a468 316 SUPERFAMILY SSF82185 128 250 1.03E-21 T 28-03-2018 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 1.1E-21 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.1E-21 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 1.1E-21 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 1.1E-21 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 147 2.7E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 SUPERFAMILY SSF52788 1 151 1.7E-51 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 Gene3D G3DSA:3.40.50.2300 1 159 2.5E-51 T 28-03-2018 AFA_RS07705 e76c3317212b8af64e00d938bebb457e 162 SMART SM00226 2 151 7.1E-51 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily AFA_RS09605 cde652fae7e91051755a51fb39184301 526 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 6 510 2.6E-121 T 28-03-2018 IPR021207 Integrating conjugative element protein, PFL4705 AFA_RS05605 fe0ac3b8e94eedf5d4124d2ecb123aab 362 Pfam PF01594 AI-2E family transporter 13 341 1.6E-53 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.0E-19 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 1.0E-19 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 1.0E-19 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.0E-19 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.0E-19 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 Pfam PF01494 FAD binding domain 5 347 8.3E-26 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 SUPERFAMILY SSF54373 176 277 2.12E-7 T 28-03-2018 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 SUPERFAMILY SSF51905 5 172 4.02E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 SUPERFAMILY SSF51905 273 371 4.02E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08345 9f2ae7e4913e5b35ca671401cbc06363 379 Gene3D G3DSA:3.50.50.60 3 356 2.9E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS13565 c01ecc91ed21279ed04ec1a6499a1e3d 348 SUPERFAMILY SSF144052 22 338 3.01E-9 T 28-03-2018 AFA_RS00190 9cad5bb80d5a7bcb3358c75796f6d665 408 SUPERFAMILY SSF53383 12 405 4.71E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS00190 9cad5bb80d5a7bcb3358c75796f6d665 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFA_RS00190 9cad5bb80d5a7bcb3358c75796f6d665 408 Gene3D G3DSA:3.90.1150.10 283 408 2.2E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS00190 9cad5bb80d5a7bcb3358c75796f6d665 408 Pfam PF00155 Aminotransferase class I and II 41 400 1.3E-69 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS00190 9cad5bb80d5a7bcb3358c75796f6d665 408 Gene3D G3DSA:3.40.640.10 54 282 2.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS09675 4a8cbe8ce218697d31665747d26d9772 108 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 2.1E-17 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFA_RS09675 4a8cbe8ce218697d31665747d26d9772 108 SUPERFAMILY SSF50118 1 106 1.21E-23 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFA_RS09675 4a8cbe8ce218697d31665747d26d9772 108 Gene3D G3DSA:2.30.30.110 1 105 2.0E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.754 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 Gene3D G3DSA:3.60.20.10 44 272 8.2E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 SUPERFAMILY SSF53271 252 482 2.42E-69 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 2.9E-154 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 SUPERFAMILY SSF56235 2 259 2.49E-69 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 Gene3D G3DSA:3.40.50.2020 277 446 5.7E-32 T 28-03-2018 AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 Pfam PF13522 Glutamine amidotransferase domain 65 210 4.0E-18 T 28-03-2018 AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 PIRSF PIRSF000485 1 482 3.9E-153 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFA_RS10240 7dc4cacac17adecb99b291ce5b789c65 494 Pfam PF00156 Phosphoribosyl transferase domain 294 394 7.4E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Gene3D G3DSA:1.10.10.10 81 130 1.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Pfam PF04545 Sigma-70, region 4 184 233 2.7E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PRINTS PR00046 Major sigma-70 factor signature 188 200 9.3E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PRINTS PR00046 Major sigma-70 factor signature 220 231 9.3E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PRINTS PR00046 Major sigma-70 factor signature 59 67 9.3E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PRINTS PR00046 Major sigma-70 factor signature 35 48 9.3E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PRINTS PR00046 Major sigma-70 factor signature 205 220 9.3E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Pfam PF04539 Sigma-70 region 3 88 142 4.8E-9 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 PIRSF PIRSF000770 2 248 1.9E-38 T 28-03-2018 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Gene3D G3DSA:1.10.10.10 176 241 3.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 SUPERFAMILY SSF88946 5 80 1.16E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 233 9.7E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 SUPERFAMILY SSF88659 81 157 2.7E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 8 235 3.9E-76 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 35 48 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Gene3D G3DSA:1.10.1740.10 2 78 4.4E-19 T 28-03-2018 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 Pfam PF04542 Sigma-70 region 2 8 80 5.7E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS06000 97dfa058aab1dff1759bc093fbbe912e 253 SUPERFAMILY SSF88659 163 240 4.3E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFA_RS12330 c608a472c9248e4ec1d3632c1a837786 400 Pfam PF02687 FtsX-like permease family 312 395 2.0E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFA_RS12330 c608a472c9248e4ec1d3632c1a837786 400 Pfam PF12704 MacB-like periplasmic core domain 19 256 7.6E-14 T 28-03-2018 IPR025857 MacB-like periplasmic core domain AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 Pfam PF07690 Major Facilitator Superfamily 6 395 9.6E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 SUPERFAMILY SSF103473 234 443 8.89E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 SUPERFAMILY SSF103473 4 183 8.89E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 Gene3D G3DSA:1.20.1250.20 2 187 3.7E-30 T 28-03-2018 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 1.2E-6 T 28-03-2018 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 1.2E-6 T 28-03-2018 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 96 116 1.2E-6 T 28-03-2018 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 386 405 1.2E-6 T 28-03-2018 AFA_RS05550 3ac0ddb6310e7c809bad6584d9295189 457 Gene3D G3DSA:1.20.1250.20 245 445 5.5E-17 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 Gene3D G3DSA:3.30.300.30 477 618 1.7E-5 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 SUPERFAMILY SSF56801 12 299 9.29E-113 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 SUPERFAMILY SSF56801 352 614 9.29E-113 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 Pfam PF00501 AMP-binding enzyme 22 482 5.7E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 Gene3D G3DSA:2.30.38.10 403 475 2.5E-22 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 Gene3D G3DSA:3.40.50.980 14 200 5.1E-41 T 28-03-2018 AFA_RS01085 6e34d309949d965ad72e8d77cc94cf06 654 Gene3D G3DSA:3.40.50.980 201 402 9.5E-35 T 28-03-2018 AFA_RS03370 bfd9524c9451b1188927fd17d7430fbd 398 Gene3D G3DSA:3.40.1090.10 2 353 2.6E-42 T 28-03-2018 AFA_RS03370 bfd9524c9451b1188927fd17d7430fbd 398 Pfam PF01734 Patatin-like phospholipase 11 235 5.3E-22 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFA_RS03370 bfd9524c9451b1188927fd17d7430fbd 398 SUPERFAMILY SSF52151 8 288 3.4E-46 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AFA_RS09185 50b83fa54ad696b3703c925bdb1d65c5 343 Pfam PF03916 Polysulphide reductase, NrfD 11 289 1.7E-17 T 28-03-2018 IPR005614 NrfD family AFA_RS09185 50b83fa54ad696b3703c925bdb1d65c5 343 Gene3D G3DSA:1.20.1630.10 8 293 5.1E-38 T 28-03-2018 AFA_RS15855 f283337600fe26f13bef1b5a2862afec 380 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 AFA_RS15855 f283337600fe26f13bef1b5a2862afec 380 Pfam PF01098 Cell cycle protein 21 374 1.3E-99 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 AFA_RS15855 f283337600fe26f13bef1b5a2862afec 380 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 374 2.5E-125 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 PIRSF PIRSF001892 1 493 6.8E-117 T 28-03-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 SUPERFAMILY SSF56954 4 25 5.1E-72 T 28-03-2018 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 SUPERFAMILY SSF56954 53 488 5.1E-72 T 28-03-2018 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 Gene3D G3DSA:1.20.1600.10 57 491 2.5E-64 T 28-03-2018 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 Pfam PF02321 Outer membrane efflux protein 73 268 3.9E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS06425 f240a9fd7c8033aff59150c4d88556b9 493 Pfam PF02321 Outer membrane efflux protein 296 484 5.5E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS16390 1b12c34c2543afe55905f77cb7c0b2af 229 Pfam PF04972 BON domain 60 113 4.7E-12 T 28-03-2018 IPR007055 BON domain AFA_RS16390 1b12c34c2543afe55905f77cb7c0b2af 229 Pfam PF04972 BON domain 123 185 3.4E-13 T 28-03-2018 IPR007055 BON domain AFA_RS16390 1b12c34c2543afe55905f77cb7c0b2af 229 SMART SM00749 49 113 26.0 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria AFA_RS16390 1b12c34c2543afe55905f77cb7c0b2af 229 SMART SM00749 128 191 5.7E-7 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria AFA_RS12570 495ed6f7f4231f4ad714eb122795a753 363 PIRSF PIRSF001361 1 352 1.1E-161 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFA_RS12570 495ed6f7f4231f4ad714eb122795a753 363 SUPERFAMILY SSF51569 7 348 4.71E-137 T 28-03-2018 AFA_RS12570 495ed6f7f4231f4ad714eb122795a753 363 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 1.2E-164 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFA_RS12570 495ed6f7f4231f4ad714eb122795a753 363 Gene3D G3DSA:3.20.20.70 8 354 1.2E-134 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS12570 495ed6f7f4231f4ad714eb122795a753 363 Pfam PF00793 DAHP synthetase I family 44 338 8.0E-102 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFA_RS17200 dd6cd22c1a9e26ba391934a44327e9b9 258 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 257 2.0E-58 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFA_RS17200 dd6cd22c1a9e26ba391934a44327e9b9 258 SUPERFAMILY SSF102705 6 257 1.05E-73 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFA_RS17200 dd6cd22c1a9e26ba391934a44327e9b9 258 Gene3D G3DSA:3.40.1390.30 113 229 7.0E-31 T 28-03-2018 AFA_RS17200 dd6cd22c1a9e26ba391934a44327e9b9 258 Gene3D G3DSA:3.40.1390.30 1 112 1.6E-22 T 28-03-2018 AFA_RS17200 dd6cd22c1a9e26ba391934a44327e9b9 258 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 245 1.3E-54 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFA_RS07710 c00697a7e0fc23ca06ca00bdc54b6e0a 158 Gene3D G3DSA:1.10.10.10 1 146 1.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07710 c00697a7e0fc23ca06ca00bdc54b6e0a 158 Pfam PF02082 Transcriptional regulator 1 83 1.6E-27 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS07710 c00697a7e0fc23ca06ca00bdc54b6e0a 158 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 139 7.3E-64 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 AFA_RS07710 c00697a7e0fc23ca06ca00bdc54b6e0a 158 SUPERFAMILY SSF46785 2 137 1.21E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07710 c00697a7e0fc23ca06ca00bdc54b6e0a 158 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 3.8E-43 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS12955 b5e7a30a75b7281020899572c30e13d7 434 SUPERFAMILY SSF103473 34 418 1.96E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12955 b5e7a30a75b7281020899572c30e13d7 434 Gene3D G3DSA:1.20.1250.20 228 417 1.1E-20 T 28-03-2018 AFA_RS12955 b5e7a30a75b7281020899572c30e13d7 434 Pfam PF11700 Vacuole effluxer Atg22 like 63 422 2.8E-26 T 28-03-2018 IPR024671 Autophagy-related protein 22-like AFA_RS12955 b5e7a30a75b7281020899572c30e13d7 434 Gene3D G3DSA:1.20.1250.20 11 223 8.8E-15 T 28-03-2018 AFA_RS14930 48ce7d1be31b5c016a85c7a1525d6c58 306 SUPERFAMILY SSF51735 6 302 1.2E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14930 48ce7d1be31b5c016a85c7a1525d6c58 306 Gene3D G3DSA:3.30.1780.10 5 139 1.5E-33 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFA_RS14930 48ce7d1be31b5c016a85c7a1525d6c58 306 Gene3D G3DSA:3.40.50.720 140 287 1.5E-16 T 28-03-2018 AFA_RS14930 48ce7d1be31b5c016a85c7a1525d6c58 306 PIRSF PIRSF001439 1 304 3.9E-48 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS14930 48ce7d1be31b5c016a85c7a1525d6c58 306 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 11 302 3.1E-28 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 79 131 5.4E-5 T 28-03-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 Pfam PF00361 Proton-conducting membrane transporter 140 424 5.4E-79 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 9.0E-48 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 9.0E-48 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 9.0E-48 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 9.0E-48 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 9.0E-48 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13360 2b162bcb5c1e60ab8b28999fc834cbaf 499 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 13 494 1.1E-184 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS10720 7f96e785429caab259549497393262bd 163 Pfam PF00583 Acetyltransferase (GNAT) family 24 133 1.0E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS10720 7f96e785429caab259549497393262bd 163 Gene3D G3DSA:3.40.630.30 1 155 1.5E-22 T 28-03-2018 AFA_RS10720 7f96e785429caab259549497393262bd 163 SUPERFAMILY SSF55729 2 139 6.73E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS14165 185af69d5a051fa4d92bc0df58380f78 550 SUPERFAMILY SSF81442 95 532 2.35E-86 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS14165 185af69d5a051fa4d92bc0df58380f78 550 Gene3D G3DSA:1.20.210.10 85 538 1.7E-52 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS14165 185af69d5a051fa4d92bc0df58380f78 550 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 99 510 4.4E-76 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 SMART SM00900 90 179 7.5E-7 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 Gene3D G3DSA:3.30.70.20 530 668 1.6E-4 T 28-03-2018 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 Gene3D G3DSA:3.30.70.20 669 747 6.0E-5 T 28-03-2018 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 PIRSF PIRSF036354 3 737 7.5E-301 T 28-03-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 SUPERFAMILY SSF54862 625 693 1.82E-7 T 28-03-2018 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 SUPERFAMILY SSF54862 526 570 1.82E-7 T 28-03-2018 AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 Pfam PF12801 4Fe-4S binding domain 610 652 1.4E-4 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS16905 059cb52102740a63c42e7b7e9244f1b8 751 Pfam PF12801 4Fe-4S binding domain 508 554 1.3E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFA_RS07010 63c999a1e2e1202ce0fe38971e2ecf4f 327 Pfam PF00589 Phage integrase family 162 317 4.2E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS07010 63c999a1e2e1202ce0fe38971e2ecf4f 327 Gene3D G3DSA:1.10.443.10 158 327 4.9E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFA_RS07010 63c999a1e2e1202ce0fe38971e2ecf4f 327 SUPERFAMILY SSF56349 54 323 4.37E-45 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFA_RS07010 63c999a1e2e1202ce0fe38971e2ecf4f 327 Gene3D G3DSA:1.10.150.130 50 157 1.9E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal AFA_RS04940 aa36a6fc7b3ce88bd800cdb696ae43db 111 Gene3D G3DSA:2.60.120.10 1 111 1.1E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS04940 aa36a6fc7b3ce88bd800cdb696ae43db 111 Pfam PF06249 Ethanolamine utilisation protein EutQ 20 106 8.5E-10 T 28-03-2018 IPR010424 Ethanolamine utilisation EutQ AFA_RS04940 aa36a6fc7b3ce88bd800cdb696ae43db 111 SUPERFAMILY SSF51182 15 99 2.16E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS08275 e9e3cc78d321cbbec5b6ac9225e1da3c 420 Pfam PF01926 50S ribosome-binding GTPase 41 137 3.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS08275 e9e3cc78d321cbbec5b6ac9225e1da3c 420 Gene3D G3DSA:3.40.50.300 84 263 1.6E-8 T 28-03-2018 AFA_RS08275 e9e3cc78d321cbbec5b6ac9225e1da3c 420 Gene3D G3DSA:3.40.50.300 6 83 3.8E-8 T 28-03-2018 AFA_RS08275 e9e3cc78d321cbbec5b6ac9225e1da3c 420 SUPERFAMILY SSF52540 34 185 4.14E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS06180 f71cc3f430fbd9b7bc9ac8d04cc607a9 468 Pfam PF00324 Amino acid permease 17 457 4.7E-101 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 AFA_RS06180 f71cc3f430fbd9b7bc9ac8d04cc607a9 468 PIRSF PIRSF006060 1 466 5.3E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AFA_RS06180 f71cc3f430fbd9b7bc9ac8d04cc607a9 468 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 PRINTS PR00342 Rhesus blood group protein signature 105 121 1.0E-6 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 PRINTS PR00342 Rhesus blood group protein signature 205 223 1.0E-6 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 PRINTS PR00342 Rhesus blood group protein signature 236 258 1.0E-6 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 PRINTS PR00342 Rhesus blood group protein signature 291 309 1.0E-6 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 TIGRFAM TIGR00836 amt: ammonium transporter 5 411 9.2E-131 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 SUPERFAMILY SSF111352 2 387 9.68E-123 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 Pfam PF00909 Ammonium Transporter Family 8 411 3.1E-118 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFA_RS12525 cfdf49fe412e9f4ad6ebfd1fa78b3cc4 413 Gene3D G3DSA:1.10.3430.10 1 392 1.6E-127 T 28-03-2018 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 Pfam PF00814 Glycoprotease family 24 312 2.0E-98 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 8.8E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 340 60.978 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 Gene3D G3DSA:3.30.420.40 145 298 9.0E-16 T 28-03-2018 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 318 3.0E-133 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 4.5E-113 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 SUPERFAMILY SSF53067 101 313 7.45E-44 T 28-03-2018 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 Gene3D G3DSA:3.30.420.40 1 144 8.0E-37 T 28-03-2018 AFA_RS10600 e6ad0bb3b5531bab03526b04c1ab03bd 352 SUPERFAMILY SSF53067 2 122 1.19E-27 T 28-03-2018 AFA_RS12080 3f3e601d0fadd0b62d80a6b15db3e142 167 Gene3D G3DSA:3.40.630.30 1 164 4.0E-23 T 28-03-2018 AFA_RS12080 3f3e601d0fadd0b62d80a6b15db3e142 167 Pfam PF00583 Acetyltransferase (GNAT) family 53 141 2.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS12080 3f3e601d0fadd0b62d80a6b15db3e142 167 SUPERFAMILY SSF55729 2 154 3.26E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS04915 0e1898c316f2985ab1890ce5d35bcebc 216 Gene3D G3DSA:2.160.10.10 1 211 2.3E-39 T 28-03-2018 AFA_RS04915 0e1898c316f2985ab1890ce5d35bcebc 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 145 6.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS04915 0e1898c316f2985ab1890ce5d35bcebc 216 SUPERFAMILY SSF51161 59 201 1.26E-41 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS04915 0e1898c316f2985ab1890ce5d35bcebc 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 119 147 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 2 584 51.541 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 SUPERFAMILY SSF50715 373 582 9.94E-69 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 52 584 2.4E-208 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 SUPERFAMILY SSF52374 52 377 1.3E-91 T 28-03-2018 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Gene3D G3DSA:2.40.240.10 497 582 1.4E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 52 369 8.2E-103 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Gene3D G3DSA:2.40.240.10 381 496 5.7E-44 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Gene3D G3DSA:3.40.50.620 52 180 2.8E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Gene3D G3DSA:3.40.50.620 185 293 1.2E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 373 563 1.5E-51 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 55 67 1.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 84 97 1.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 PRINTS PR00987 Glutamyl-tRNA synthetase signature 238 248 1.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 Gene3D G3DSA:1.10.1160.10 294 371 1.2E-30 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 AFA_RS03570 0be054989548bbf635e95c03a40f1cfa 585 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.062 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 SUPERFAMILY SSF56770 9 151 5.36E-65 T 28-03-2018 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 4.4E-75 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 Gene3D G3DSA:3.40.50.700 11 156 2.5E-47 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13415 2ea7ebd45ac21496309ab20448b3df57 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 7.0E-22 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS10815 3958e5a629e833b4dc445ecff57659e5 160 Pfam PF03928 Haem-degrading 27 153 2.6E-26 T 28-03-2018 IPR005624 Haem-degrading AFA_RS10815 3958e5a629e833b4dc445ecff57659e5 160 SUPERFAMILY SSF143744 20 155 3.79E-33 T 28-03-2018 AFA_RS05505 718f885ffdc004da5d8787776dd2dada 317 Gene3D G3DSA:3.30.360.10 137 317 1.3E-27 T 28-03-2018 AFA_RS05505 718f885ffdc004da5d8787776dd2dada 317 SUPERFAMILY SSF55347 128 287 1.07E-12 T 28-03-2018 AFA_RS05505 718f885ffdc004da5d8787776dd2dada 317 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 7.7E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFA_RS05505 718f885ffdc004da5d8787776dd2dada 317 Gene3D G3DSA:3.40.50.720 1 136 1.0E-40 T 28-03-2018 AFA_RS05505 718f885ffdc004da5d8787776dd2dada 317 SUPERFAMILY SSF51735 3 143 1.24E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 Pfam PF01593 Flavin containing amine oxidoreductase 18 291 1.1E-17 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 447 462 5.0E-6 T 28-03-2018 AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 5.0E-6 T 28-03-2018 AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 Gene3D G3DSA:3.50.50.60 1 526 6.2E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 SUPERFAMILY SSF51905 5 336 1.19E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05480 860388ec42f973cc4877d171fd4d2f94 526 SUPERFAMILY SSF51905 484 525 1.19E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS03890 879c613c4a1b79c8bdf4ce155276ed1a 150 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 1 125 1.8E-34 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFA_RS03890 879c613c4a1b79c8bdf4ce155276ed1a 150 SUPERFAMILY SSF55083 1 146 3.79E-46 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFA_RS03890 879c613c4a1b79c8bdf4ce155276ed1a 150 Gene3D G3DSA:3.30.70.560 1 147 8.7E-51 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFA_RS03890 879c613c4a1b79c8bdf4ce155276ed1a 150 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 80 91 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFA_RS03890 879c613c4a1b79c8bdf4ce155276ed1a 150 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1 125 1.7E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFA_RS05385 b9d49113abbfad2e0a6edfaa4592c636 238 Pfam PF01522 Polysaccharide deacetylase 51 186 2.5E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFA_RS05385 b9d49113abbfad2e0a6edfaa4592c636 238 Gene3D G3DSA:3.20.20.370 10 237 3.7E-42 T 28-03-2018 AFA_RS05385 b9d49113abbfad2e0a6edfaa4592c636 238 SUPERFAMILY SSF88713 15 209 1.21E-39 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS02770 06112e02e848ee4a9dd7d7bbe14c27a5 69 Pfam PF10932 Protein of unknown function (DUF2783) 4 62 3.3E-26 T 28-03-2018 IPR021233 Protein of unknown function DUF2783 AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 Gene3D G3DSA:1.10.10.10 142 251 1.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 245 2.2E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 Gene3D G3DSA:3.40.50.2300 21 136 7.8E-5 T 28-03-2018 AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 SUPERFAMILY SSF52172 19 136 4.73E-5 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 SMART SM00862 163 245 0.0022 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS15790 931eb8b233dc0e144edf9dda9f018a6d 258 SUPERFAMILY SSF46894 146 247 1.3E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 SUPERFAMILY SSF51445 216 558 1.79E-29 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 Gene3D G3DSA:2.60.40.1180 580 640 6.1E-22 T 28-03-2018 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 Pfam PF01055 Glycosyl hydrolases family 31 208 644 2.0E-66 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 Gene3D G3DSA:3.20.20.80 214 579 1.4E-57 T 28-03-2018 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 SUPERFAMILY SSF51011 560 639 3.16E-19 T 28-03-2018 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 Gene3D G3DSA:2.60.40.1760 9 213 3.6E-32 T 28-03-2018 AFA_RS03750 31f3e62eb2f2b7ffe57deec8e578bc80 722 SUPERFAMILY SSF74650 23 213 3.77E-25 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 AFA_RS12820 3dda7709ba89cc453415286335a864cc 382 Gene3D G3DSA:1.20.1250.20 186 382 1.3E-12 T 28-03-2018 AFA_RS12820 3dda7709ba89cc453415286335a864cc 382 Gene3D G3DSA:1.20.1250.20 2 179 2.4E-27 T 28-03-2018 AFA_RS12820 3dda7709ba89cc453415286335a864cc 382 Pfam PF07690 Major Facilitator Superfamily 3 344 1.5E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS12820 3dda7709ba89cc453415286335a864cc 382 SUPERFAMILY SSF103473 2 377 1.14E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS12820 3dda7709ba89cc453415286335a864cc 382 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 373 4.4E-91 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 41 88 1.3E-21 T 28-03-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 38 297 3.8E-76 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 SUPERFAMILY SSF46626 214 299 7.02E-24 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 Gene3D G3DSA:1.10.760.10 95 210 1.0E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 PIRSF PIRSF000006 5 299 1.1E-97 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 133 204 1.9E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 219 292 1.4E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 Gene3D G3DSA:1.10.760.10 211 304 9.0E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 SUPERFAMILY SSF46626 60 83 6.4E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11745 be71b6902bdb946c3b427f9041347106 304 SUPERFAMILY SSF46626 111 210 6.4E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11135 b8b723be9fe2b8315cdf3681d8c0e36e 611 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 611 31.845 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup AFA_RS11135 b8b723be9fe2b8315cdf3681d8c0e36e 611 Pfam PF02705 K+ potassium transporter 2 529 8.1E-199 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 AFA_RS01455 fb062f237ba84bd648f5cf1417025c5f 225 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 104 201 3.1E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS01455 fb062f237ba84bd648f5cf1417025c5f 225 SUPERFAMILY SSF56214 104 214 6.28E-16 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS01455 fb062f237ba84bd648f5cf1417025c5f 225 Gene3D G3DSA:3.90.470.20 4 113 7.8E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS01455 fb062f237ba84bd648f5cf1417025c5f 225 SUPERFAMILY SSF56214 7 96 6.1E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS01455 fb062f237ba84bd648f5cf1417025c5f 225 Gene3D G3DSA:3.90.470.20 114 202 3.3E-7 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AFA_RS00425 e58ec4ee3d9af0988c98d65da6a1911a 328 Gene3D G3DSA:1.10.3720.10 4 308 2.9E-42 T 28-03-2018 AFA_RS00425 e58ec4ee3d9af0988c98d65da6a1911a 328 SUPERFAMILY SSF161098 92 306 7.72E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS00425 e58ec4ee3d9af0988c98d65da6a1911a 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.9E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS08750 67db001370c1b748e147a26c4ea6d1bb 270 SUPERFAMILY SSF47240 70 217 1.81E-17 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS08750 67db001370c1b748e147a26c4ea6d1bb 270 Pfam PF04305 Protein of unknown function (DUF455) 14 253 4.2E-86 T 28-03-2018 IPR007402 Protein of unknown function DUF455 AFA_RS08750 67db001370c1b748e147a26c4ea6d1bb 270 PIRSF PIRSF012318 1 267 1.2E-87 T 28-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 AFA_RS08750 67db001370c1b748e147a26c4ea6d1bb 270 Gene3D G3DSA:1.20.1260.10 52 247 1.7E-38 T 28-03-2018 IPR012347 Ferritin-related AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.1E-85 T 28-03-2018 AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 PIRSF PIRSF000094 1 261 8.4E-112 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 Gene3D G3DSA:3.40.50.720 44 259 4.2E-38 T 28-03-2018 AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 Gene3D G3DSA:3.40.50.720 2 43 0.012 T 28-03-2018 AFA_RS15215 f10bb46a6c7bcff92d502288b23c271d 261 SUPERFAMILY SSF51735 5 254 5.53E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 44 314 2.9E-22 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 1.9E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 SUPERFAMILY SSF51735 102 284 3.73E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 Gene3D G3DSA:3.40.50.720 116 286 1.2E-48 T 28-03-2018 AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 SUPERFAMILY SSF52283 3 137 2.13E-30 T 28-03-2018 AFA_RS17275 9c5b87a14aadf9041c14be7f35cdd069 316 Gene3D G3DSA:3.40.50.720 4 115 5.0E-27 T 28-03-2018 AFA_RS08925 2397e088eabaedac31d820436f5419a0 311 SUPERFAMILY SSF56317 3 300 4.58E-71 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS08925 2397e088eabaedac31d820436f5419a0 311 Pfam PF00795 Carbon-nitrogen hydrolase 7 282 4.6E-52 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS08925 2397e088eabaedac31d820436f5419a0 311 Gene3D G3DSA:3.60.110.10 1 298 6.2E-55 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00790 60caea569a80297a2859dc30f9d8efb4 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 424 2.5E-99 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00790 60caea569a80297a2859dc30f9d8efb4 432 PIRSF PIRSF006066 5 432 1.3E-101 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00790 60caea569a80297a2859dc30f9d8efb4 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 429 1.0E-107 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS05000 2debec78c17d093298e5a516a4d9c914 380 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 15 376 2.7E-148 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition AFA_RS05000 2debec78c17d093298e5a516a4d9c914 380 Gene3D G3DSA:3.40.630.30 187 334 2.2E-33 T 28-03-2018 AFA_RS05000 2debec78c17d093298e5a516a4d9c914 380 Gene3D G3DSA:3.40.630.30 13 186 1.8E-17 T 28-03-2018 AFA_RS05000 2debec78c17d093298e5a516a4d9c914 380 SUPERFAMILY SSF55729 179 353 7.42E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS06665 434ae70def605c7af3e310e7dc99da21 161 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 43 158 2.2E-12 T 28-03-2018 IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain GO:0004683|GO:0005516|GO:0006468 Reactome: R-HSA-3371571|Reactome: R-HSA-399719|Reactome: R-HSA-438066|Reactome: R-HSA-442729|Reactome: R-HSA-442742|Reactome: R-HSA-442982|Reactome: R-HSA-5576892|Reactome: R-HSA-5578775|Reactome: R-HSA-5673001|Reactome: R-HSA-877300|Reactome: R-HSA-936837 AFA_RS06665 434ae70def605c7af3e310e7dc99da21 161 SUPERFAMILY SSF54427 39 155 1.8E-20 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS06665 434ae70def605c7af3e310e7dc99da21 161 Gene3D G3DSA:3.10.450.50 38 161 2.0E-15 T 28-03-2018 AFA_RS06665 434ae70def605c7af3e310e7dc99da21 161 PIRSF PIRSF028470 1 160 3.7E-47 T 28-03-2018 IPR016887 Uncharacterised conserved protein UCP028470, steroid isomerase-related AFA_RS16775 10930af002b53f01491748471c47bff0 316 SUPERFAMILY SSF56317 3 300 4.84E-68 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS16775 10930af002b53f01491748471c47bff0 316 Pfam PF00795 Carbon-nitrogen hydrolase 3 278 4.7E-47 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS16775 10930af002b53f01491748471c47bff0 316 Gene3D G3DSA:3.60.110.10 2 315 1.9E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS11390 bad1bac30359c585492a84cf54e9a518 220 Gene3D G3DSA:3.40.50.1820 1 220 5.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS11390 bad1bac30359c585492a84cf54e9a518 220 Pfam PF01738 Dienelactone hydrolase family 14 218 3.4E-45 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFA_RS11390 bad1bac30359c585492a84cf54e9a518 220 SUPERFAMILY SSF53474 4 219 1.36E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 Pfam PF10411 Disulfide bond isomerase protein N-terminus 39 94 7.0E-15 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 SUPERFAMILY SSF52833 91 245 2.7E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 Gene3D G3DSA:3.40.30.10 113 248 1.3E-14 T 28-03-2018 AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 SUPERFAMILY SSF54423 46 94 8.24E-9 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 Pfam PF13098 Thioredoxin-like domain 123 244 9.7E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS09700 5fb4cc5709e5fe1bcb6047f503be3277 252 Gene3D G3DSA:3.10.450.70 31 95 1.9E-15 T 28-03-2018 AFA_RS17285 d5c4aa0f71da7b3ce5fae6916e14d2b8 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 419 2.3E-94 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS17285 d5c4aa0f71da7b3ce5fae6916e14d2b8 430 PIRSF PIRSF006066 2 430 7.9E-95 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS17285 d5c4aa0f71da7b3ce5fae6916e14d2b8 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 19 426 1.6E-98 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 Gene3D G3DSA:2.30.30.30 2 92 3.8E-28 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 102 1.6E-31 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 18.972 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 SUPERFAMILY SSF50104 3 100 1.08E-29 T 28-03-2018 IPR008991 Translation protein SH3-like domain AFA_RS18045 db50af4f7585e6238205c439d732f82b 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 3.6E-24 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS01930 6658154f1c828e11c817b8a31a3fd251 345 Gene3D G3DSA:3.60.60.10 96 336 9.4E-10 T 28-03-2018 AFA_RS01930 6658154f1c828e11c817b8a31a3fd251 345 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 111 326 1.8E-43 T 28-03-2018 IPR005079 Peptidase C45 AFA_RS16655 18a1b0ea9f70b6a7cda1a60eaf314020 351 SUPERFAMILY SSF52402 32 251 1.76E-56 T 28-03-2018 AFA_RS16655 18a1b0ea9f70b6a7cda1a60eaf314020 351 Gene3D G3DSA:3.40.50.620 22 253 7.0E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS16655 18a1b0ea9f70b6a7cda1a60eaf314020 351 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 8 286 56.536 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 AFA_RS16655 18a1b0ea9f70b6a7cda1a60eaf314020 351 Pfam PF01171 PP-loop family 56 219 8.8E-16 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 8.3E-125 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Gene3D G3DSA:1.20.272.10 243 362 5.1E-6 T 28-03-2018 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.5E-38 T 28-03-2018 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 SUPERFAMILY SSF52540 34 225 1.12E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Gene3D G3DSA:1.10.8.60 167 242 1.9E-17 T 28-03-2018 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 362 3.5E-20 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Gene3D G3DSA:3.40.50.300 2 166 9.8E-39 T 28-03-2018 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 681 798 2.7E-6 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 SUPERFAMILY SSF48019 243 363 4.25E-25 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFA_RS04090 d10686ebda1f018a79d1471635a46e2f 807 SMART SM00382 37 179 2.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 Gene3D G3DSA:2.30.40.10 1 75 7.4E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 Gene3D G3DSA:3.20.20.140 76 357 2.4E-53 T 28-03-2018 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 TIGRFAM TIGR01224 hutI: imidazolonepropionase 23 399 8.3E-141 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 SUPERFAMILY SSF51556 62 358 3.28E-85 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 Pfam PF01979 Amidohydrolase family 59 387 2.3E-13 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 SUPERFAMILY SSF51338 363 399 1.36E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 SUPERFAMILY SSF51338 4 62 1.36E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AFA_RS17650 a93134c08f728d362d881fa026ea75be 409 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 401 41.294 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS05970 be3c77c22db52b42a0bd240e6662041e 109 Pfam PF01312 FlhB HrpN YscU SpaS Family 11 86 1.6E-19 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFA_RS05970 be3c77c22db52b42a0bd240e6662041e 109 SUPERFAMILY SSF160544 10 90 1.44E-24 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFA_RS05970 be3c77c22db52b42a0bd240e6662041e 109 Gene3D G3DSA:3.40.1690.10 14 89 1.6E-30 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFA_RS00610 89da57bf51eebf9a89399a097773b069 267 Gene3D G3DSA:2.170.270.10 2 150 3.2E-37 T 28-03-2018 AFA_RS00610 89da57bf51eebf9a89399a097773b069 267 SMART SM00317 6 127 1.9E-26 T 28-03-2018 IPR001214 SET domain GO:0005515 AFA_RS00610 89da57bf51eebf9a89399a097773b069 267 SUPERFAMILY SSF82199 5 147 3.01E-39 T 28-03-2018 AFA_RS00610 89da57bf51eebf9a89399a097773b069 267 Pfam PF00856 SET domain 18 120 2.1E-17 T 28-03-2018 IPR001214 SET domain GO:0005515 AFA_RS08990 b2b238cd04e7f7eb73a7820a7080985c 376 Gene3D G3DSA:3.50.50.60 1 376 1.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08990 b2b238cd04e7f7eb73a7820a7080985c 376 Pfam PF01266 FAD dependent oxidoreductase 4 348 5.7E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFA_RS08990 b2b238cd04e7f7eb73a7820a7080985c 376 SUPERFAMILY SSF51905 3 217 2.46E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS08990 b2b238cd04e7f7eb73a7820a7080985c 376 SUPERFAMILY SSF51905 310 365 2.46E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10060 19b22b1b926cb135d71d2ffbc071dc00 345 Gene3D G3DSA:1.20.272.10 233 345 7.4E-7 T 28-03-2018 AFA_RS10060 19b22b1b926cb135d71d2ffbc071dc00 345 Pfam PF13177 DNA polymerase III, delta subunit 17 187 2.9E-37 T 28-03-2018 AFA_RS10060 19b22b1b926cb135d71d2ffbc071dc00 345 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 18 219 2.4E-62 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFA_RS10060 19b22b1b926cb135d71d2ffbc071dc00 345 Gene3D G3DSA:3.40.50.300 9 185 4.8E-22 T 28-03-2018 AFA_RS10060 19b22b1b926cb135d71d2ffbc071dc00 345 SUPERFAMILY SSF52540 4 218 3.4E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 Pfam PF00106 short chain dehydrogenase 12 194 3.9E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 SUPERFAMILY SSF51735 10 250 5.17E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 Gene3D G3DSA:3.40.50.720 5 256 2.2E-46 T 28-03-2018 AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16960 881ca0ff41a459e876bdab38bad32124 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS10545 96a7bf4d155c5902bbe48344341b0044 436 Pfam PF00924 Mechanosensitive ion channel 149 403 1.5E-45 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFA_RS10545 96a7bf4d155c5902bbe48344341b0044 436 SUPERFAMILY SSF50182 191 258 1.05E-10 T 28-03-2018 IPR010920 LSM domain AFA_RS10545 96a7bf4d155c5902bbe48344341b0044 436 Gene3D G3DSA:2.30.30.60 208 258 1.9E-10 T 28-03-2018 AFA_RS00650 b74e40d015c3e5a806283ce9cb8d450e 274 Pfam PF09925 Predicted membrane protein (DUF2157) 8 116 3.6E-21 T 28-03-2018 IPR018677 Domain of unknown function DUF2157 AFA_RS03920 94190181e676d5377da05d08b883284f 312 Pfam PF01715 IPP transferase 40 287 3.1E-86 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFA_RS03920 94190181e676d5377da05d08b883284f 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 287 7.2E-95 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFA_RS03920 94190181e676d5377da05d08b883284f 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 304 28.866 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFA_RS03920 94190181e676d5377da05d08b883284f 312 Gene3D G3DSA:1.10.287.890 203 284 2.3E-26 T 28-03-2018 AFA_RS03920 94190181e676d5377da05d08b883284f 312 Gene3D G3DSA:3.40.50.300 3 198 8.6E-59 T 28-03-2018 AFA_RS03920 94190181e676d5377da05d08b883284f 312 SUPERFAMILY SSF52540 7 149 1.47E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13170 d1ae441939f878f3233994596a123923 302 Gene3D G3DSA:3.30.2350.10 78 302 9.4E-67 T 28-03-2018 AFA_RS13170 d1ae441939f878f3233994596a123923 302 SUPERFAMILY SSF55120 78 298 2.4E-65 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS13170 d1ae441939f878f3233994596a123923 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 125 139 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS13170 d1ae441939f878f3233994596a123923 302 SMART SM00363 11 72 1.1E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS13170 d1ae441939f878f3233994596a123923 302 Gene3D G3DSA:3.10.290.10 2 71 4.1E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS13170 d1ae441939f878f3233994596a123923 302 SUPERFAMILY SSF55174 10 62 4.21E-8 T 28-03-2018 AFA_RS13170 d1ae441939f878f3233994596a123923 302 Pfam PF00849 RNA pseudouridylate synthase 86 235 3.4E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS13170 d1ae441939f878f3233994596a123923 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 8 298 7.2E-80 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFA_RS13170 d1ae441939f878f3233994596a123923 302 Pfam PF01479 S4 domain 11 57 1.3E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS08615 856a0f0b1ea5736940faab309cfa4610 109 SUPERFAMILY SSF51182 23 95 1.26E-10 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS08615 856a0f0b1ea5736940faab309cfa4610 109 Gene3D G3DSA:2.60.120.10 2 109 1.8E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS13250 b0b5890a99f456363fe02616f5c6d333 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 101 330 5.5E-21 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS13250 b0b5890a99f456363fe02616f5c6d333 345 Gene3D G3DSA:1.10.3470.10 3 98 2.1E-5 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS13250 b0b5890a99f456363fe02616f5c6d333 345 Gene3D G3DSA:1.10.3470.10 99 340 9.0E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS07545 687c76d2ac1bcd90bef7817e12dfda3b 102 SUPERFAMILY SSF46626 6 101 4.66E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS07545 687c76d2ac1bcd90bef7817e12dfda3b 102 Gene3D G3DSA:1.10.760.10 13 102 4.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS07545 687c76d2ac1bcd90bef7817e12dfda3b 102 PRINTS PR00605 Class IC cytochrome C signature 74 96 4.6E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS07545 687c76d2ac1bcd90bef7817e12dfda3b 102 PRINTS PR00605 Class IC cytochrome C signature 35 46 4.6E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS07545 687c76d2ac1bcd90bef7817e12dfda3b 102 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 96 4.9E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS00120 db91224df4823d05272f01bd39288258 535 SUPERFAMILY SSF52540 293 526 1.64E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00120 db91224df4823d05272f01bd39288258 535 Gene3D G3DSA:3.40.50.300 1 279 2.9E-49 T 28-03-2018 AFA_RS00120 db91224df4823d05272f01bd39288258 535 Gene3D G3DSA:3.40.50.300 291 534 2.8E-56 T 28-03-2018 AFA_RS00120 db91224df4823d05272f01bd39288258 535 SUPERFAMILY SSF52540 5 250 1.3E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00120 db91224df4823d05272f01bd39288258 535 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 1.3E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS00120 db91224df4823d05272f01bd39288258 535 Pfam PF00005 ABC transporter 310 455 3.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00120 db91224df4823d05272f01bd39288258 535 Pfam PF00005 ABC transporter 21 179 1.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS00120 db91224df4823d05272f01bd39288258 535 SMART SM00382 29 227 2.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS00120 db91224df4823d05272f01bd39288258 535 SMART SM00382 319 504 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13940 952448d9b48c6250e6cda37be021c9d7 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 87 261 8.0E-18 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS13940 952448d9b48c6250e6cda37be021c9d7 265 SUPERFAMILY SSF56529 8 262 5.23E-80 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS13940 952448d9b48c6250e6cda37be021c9d7 265 Gene3D G3DSA:3.90.850.10 3 265 6.0E-55 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS07285 477123bfd3c3e8047417cac0643f2f57 250 Pfam PF00117 Glutamine amidotransferase class-I 44 141 6.4E-7 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS07285 477123bfd3c3e8047417cac0643f2f57 250 SUPERFAMILY SSF52317 31 201 7.12E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07285 477123bfd3c3e8047417cac0643f2f57 250 Gene3D G3DSA:3.40.50.880 2 229 2.9E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 Gene3D G3DSA:3.40.50.10860 50 193 4.6E-55 T 28-03-2018 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 227 247 1.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 185 207 1.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 1.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 105 119 1.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 176 1.3E-55 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 SUPERFAMILY SSF51735 194 428 4.3E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 SUPERFAMILY SSF53223 17 196 1.89E-67 T 28-03-2018 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 113 126 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 PIRSF PIRSF000185 21 429 2.1E-163 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 194 426 5.7E-76 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 SMART SM00839 196 426 9.3E-102 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFA_RS01065 666be8a0e5748c75a6ac0102585d7b9b 429 Gene3D G3DSA:3.40.50.720 194 429 1.9E-77 T 28-03-2018 AFA_RS14840 69da9341ac786ad97218ab480d8cb5b0 328 PIRSF PIRSF017082 4 328 4.7E-84 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS14840 69da9341ac786ad97218ab480d8cb5b0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 324 3.0E-88 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS14840 69da9341ac786ad97218ab480d8cb5b0 328 SUPERFAMILY SSF53850 115 286 1.52E-8 T 28-03-2018 AFA_RS14840 69da9341ac786ad97218ab480d8cb5b0 328 Gene3D G3DSA:3.40.190.10 125 237 3.5E-9 T 28-03-2018 AFA_RS01170 b422a357c278a30fdd04e915c3d47380 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 36 165 1.6E-18 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS08455 f05d58576debe8f5ede39e7248aaed12 139 SUPERFAMILY SSF51316 6 131 3.24E-35 T 28-03-2018 IPR011057 Mss4-like AFA_RS08455 f05d58576debe8f5ede39e7248aaed12 139 Gene3D G3DSA:3.90.1590.10 1 134 1.4E-28 T 28-03-2018 AFA_RS08455 f05d58576debe8f5ede39e7248aaed12 139 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 30 114 7.7E-13 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFA_RS11115 432f311b1b0f4563e6cb459e7f06947c 161 Pfam PF01899 Na+/H+ ion antiporter subunit 12 159 8.7E-34 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AFA_RS11115 432f311b1b0f4563e6cb459e7f06947c 161 PIRSF PIRSF019239 1 161 1.1E-34 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 264 4.2E-99 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 10 269 1.8E-90 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 SUPERFAMILY SSF51621 10 269 6.28E-92 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 PIRSF PIRSF000388 1 272 3.5E-99 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 Gene3D G3DSA:3.20.20.60 2 269 3.4E-74 T 28-03-2018 AFA_RS17350 43e072301642de0ca2b1c47d0823ff4d 273 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 38.735 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFA_RS04000 ad946a165440bf0741c0f6a8b0c4316c 439 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 428 3.4E-75 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS04000 ad946a165440bf0741c0f6a8b0c4316c 439 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 433 1.2E-87 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS04000 ad946a165440bf0741c0f6a8b0c4316c 439 PIRSF PIRSF006066 4 438 4.1E-69 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 SUPERFAMILY SSF46458 11 119 6.96E-23 T 28-03-2018 IPR009050 Globin-like AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 Pfam PF01152 Bacterial-like globin 12 106 8.6E-7 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 Pfam PF09313 Domain of unknown function (DUF1971) 143 209 1.9E-17 T 28-03-2018 IPR015392 Domain of unknown function DUF1971 AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 Gene3D G3DSA:1.10.490.10 5 127 1.9E-21 T 28-03-2018 AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 SUPERFAMILY SSF51197 134 222 7.28E-22 T 28-03-2018 AFA_RS16815 e87fbb93410fd2e67fe994bccd5d2da4 224 Gene3D G3DSA:2.60.120.10 134 224 5.4E-25 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 Gene3D G3DSA:2.60.40.650 288 405 3.7E-29 T 28-03-2018 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 285 396 8.6E-15 T 28-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 211 227 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 132 143 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 371 383 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 384 397 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 228 241 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 77 93 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 244 257 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 PRINTS PR00407 Eukaryotic molybdopterin domain signature 326 338 3.6E-19 T 28-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 SUPERFAMILY SSF56524 57 321 1.14E-50 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 SUPERFAMILY SSF81296 288 402 5.6E-26 T 28-03-2018 IPR014756 Immunoglobulin E-set AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 Gene3D G3DSA:3.90.420.10 22 282 1.6E-47 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS07540 abaf315214ec37edb635a0325fc68c75 406 Pfam PF00174 Oxidoreductase molybdopterin binding domain 99 262 1.7E-41 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AFA_RS10135 ed94b48a41780441f2df134d83a1e33e 260 SUPERFAMILY SSF55315 3 103 3.06E-7 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like AFA_RS10135 ed94b48a41780441f2df134d83a1e33e 260 Pfam PF00588 SpoU rRNA Methylase family 115 252 1.1E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFA_RS10135 ed94b48a41780441f2df134d83a1e33e 260 Gene3D G3DSA:3.30.1330.30 3 105 1.1E-7 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like AFA_RS10135 ed94b48a41780441f2df134d83a1e33e 260 Gene3D G3DSA:3.40.1280.10 106 260 3.4E-42 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFA_RS10135 ed94b48a41780441f2df134d83a1e33e 260 SUPERFAMILY SSF75217 112 258 3.79E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases AFA_RS10040 f3ce55e947acb37fdf020892d3e198e6 263 Gene3D G3DSA:3.90.640.20 169 263 2.3E-18 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 AFA_RS10040 f3ce55e947acb37fdf020892d3e198e6 263 Gene3D G3DSA:3.30.565.40 37 164 1.1E-11 T 28-03-2018 AFA_RS10040 f3ce55e947acb37fdf020892d3e198e6 263 Pfam PF11738 Protein of unknown function (DUF3298) 202 249 1.6E-10 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 Pfam PF01872 RibD C-terminal domain 153 333 2.4E-39 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 SUPERFAMILY SSF53927 6 151 1.95E-45 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 356 4.6E-101 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 Gene3D G3DSA:3.40.140.10 2 130 9.3E-31 T 28-03-2018 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 105 2.0E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 152 360 3.1E-45 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 Gene3D G3DSA:3.40.430.10 131 369 1.0E-61 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 PIRSF PIRSF006769 1 364 3.0E-108 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFA_RS15470 202a390a2cdd5336fed6a15180c06ddf 382 SUPERFAMILY SSF53597 151 362 8.57E-54 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AFA_RS02900 5c9534488e04bb0aea2b27cbe8dd8968 60 Pfam PF04995 Heme exporter protein D (CcmD) 13 55 2.7E-10 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 AFA_RS02900 5c9534488e04bb0aea2b27cbe8dd8968 60 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 53 1.1E-12 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 385 1.2E-101 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 Gene3D G3DSA:3.40.640.10 6 258 4.4E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 SUPERFAMILY SSF53383 29 387 1.57E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 Gene3D G3DSA:3.90.1150.10 259 391 5.9E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 PIRSF PIRSF001434 2 389 2.6E-118 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 9 387 4.1E-139 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 AFA_RS07225 f73a41a654c61324aeb670bce5de7e71 407 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFA_RS02610 15d2169d27d17e5c2286cb2ed2ade5dd 551 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 98 508 2.7E-74 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS02610 15d2169d27d17e5c2286cb2ed2ade5dd 551 Gene3D G3DSA:1.20.210.10 85 533 6.0E-51 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS02610 15d2169d27d17e5c2286cb2ed2ade5dd 551 SUPERFAMILY SSF81442 94 530 3.27E-86 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 Pfam PF01012 Electron transfer flavoprotein domain 4 170 8.9E-42 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 SUPERFAMILY SSF52402 3 186 2.02E-59 T 28-03-2018 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 6.9E-36 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 SUPERFAMILY SSF52467 189 308 1.25E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 SMART SM00893 3 182 3.0E-59 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 PIRSF PIRSF000089 1 309 1.1E-107 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 Gene3D G3DSA:3.40.50.620 1 183 1.3E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS11905 5e9a59ab63ac64ebe56a250662da945c 309 Gene3D G3DSA:3.40.50.1220 185 309 3.3E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 Gene3D G3DSA:3.40.50.2300 157 328 9.3E-26 T 28-03-2018 AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 SUPERFAMILY SSF53822 23 379 1.14E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 260 278 1.0E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 1.0E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 1.0E-7 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 Pfam PF13458 Periplasmic binding protein 24 375 6.7E-61 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS00105 a4af3c2cad8d25de39561d5fc1073ae4 385 Gene3D G3DSA:3.40.50.2300 24 156 2.5E-18 T 28-03-2018 AFA_RS08370 a43b84bada726a605d359c2ce7b7ac98 289 Pfam PF00892 EamA-like transporter family 12 136 2.8E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS08370 a43b84bada726a605d359c2ce7b7ac98 289 Pfam PF00892 EamA-like transporter family 146 279 6.1E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS08370 a43b84bada726a605d359c2ce7b7ac98 289 SUPERFAMILY SSF103481 43 139 2.62E-11 T 28-03-2018 AFA_RS08370 a43b84bada726a605d359c2ce7b7ac98 289 SUPERFAMILY SSF103481 180 285 6.93E-15 T 28-03-2018 AFA_RS11850 91dea4f830f19dc110ad0611d907c81d 94 Pfam PF06243 Phenylacetic acid degradation B 5 90 2.2E-38 T 28-03-2018 IPR009359 Phenylacetic acid degradation B AFA_RS11850 91dea4f830f19dc110ad0611d907c81d 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 93 5.2E-41 T 28-03-2018 IPR009359 Phenylacetic acid degradation B AFA_RS11850 91dea4f830f19dc110ad0611d907c81d 94 PIRSF PIRSF030200 1 94 6.1E-41 T 28-03-2018 IPR009359 Phenylacetic acid degradation B AFA_RS17380 c2bd856cfa8330a1245c09f4a02bcee7 267 SUPERFAMILY SSF53187 1 263 3.08E-80 T 28-03-2018 AFA_RS17380 c2bd856cfa8330a1245c09f4a02bcee7 267 Gene3D G3DSA:3.40.630.40 2 267 6.9E-79 T 28-03-2018 AFA_RS17380 c2bd856cfa8330a1245c09f4a02bcee7 267 Pfam PF05013 N-formylglutamate amidohydrolase 14 233 5.4E-70 T 28-03-2018 IPR007709 N-formylglutamate amidohydrolase AFA_RS17380 c2bd856cfa8330a1245c09f4a02bcee7 267 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 7 265 6.7E-109 T 28-03-2018 IPR010247 N-formylglutamate deformylase AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 SUPERFAMILY SSF53850 89 297 5.61E-43 T 28-03-2018 AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 SUPERFAMILY SSF46785 4 85 6.53E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 Pfam PF03466 LysR substrate binding domain 89 292 1.1E-40 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 Gene3D G3DSA:3.40.190.10 178 265 9.5E-28 T 28-03-2018 AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 Gene3D G3DSA:1.10.10.10 3 83 4.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02490 70901857b2d17b640a5854da8c0b15ef 299 Gene3D G3DSA:3.40.190.10 91 177 4.1E-13 T 28-03-2018 AFA_RS03525 9800f8267562fe86e94cba67c84ee91e 307 Gene3D G3DSA:3.90.550.10 3 271 1.3E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS03525 9800f8267562fe86e94cba67c84ee91e 307 Pfam PF00535 Glycosyl transferase family 2 8 112 2.4E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS03525 9800f8267562fe86e94cba67c84ee91e 307 SUPERFAMILY SSF53448 6 225 5.56E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS17005 6d5579e479f8c38a9edb7f7325487038 373 Gene3D G3DSA:3.40.50.2000 1 209 4.0E-77 T 28-03-2018 AFA_RS17005 6d5579e479f8c38a9edb7f7325487038 373 SUPERFAMILY SSF53756 1 371 2.51E-139 T 28-03-2018 AFA_RS17005 6d5579e479f8c38a9edb7f7325487038 373 Gene3D G3DSA:3.40.50.2000 210 355 2.8E-38 T 28-03-2018 AFA_RS17005 6d5579e479f8c38a9edb7f7325487038 373 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 370 2.2E-156 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 AFA_RS17005 6d5579e479f8c38a9edb7f7325487038 373 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 21 369 5.7E-125 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 AFA_RS01530 5962e04a6dff8796fa60766f57109326 261 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS01530 5962e04a6dff8796fa60766f57109326 261 Gene3D G3DSA:3.40.50.300 1 250 1.2E-54 T 28-03-2018 AFA_RS01530 5962e04a6dff8796fa60766f57109326 261 SMART SM00382 27 215 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01530 5962e04a6dff8796fa60766f57109326 261 SUPERFAMILY SSF52540 2 229 3.59E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01530 5962e04a6dff8796fa60766f57109326 261 Pfam PF00005 ABC transporter 25 165 1.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 Gene3D G3DSA:2.40.170.20 191 731 3.4E-74 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 730 1.7E-102 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 SUPERFAMILY SSF56935 33 730 3.43E-120 T 28-03-2018 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 Gene3D G3DSA:2.170.130.10 38 190 5.1E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 81 181 2.3E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS13830 3e0fe969e8037a2da3e5bc26684d901c 731 Pfam PF00593 TonB dependent receptor 288 729 4.8E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS07880 cd27216b7248193d625ea187a9793dd6 475 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 63 277 3.1E-40 T 28-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 AFA_RS07880 cd27216b7248193d625ea187a9793dd6 475 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 28 337 3.7E-78 T 28-03-2018 IPR014150 Conjugal transfer, TrbL AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 Pfam PF13458 Periplasmic binding protein 29 361 1.7E-59 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 Gene3D G3DSA:3.40.50.2300 283 366 2.0E-9 T 28-03-2018 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 333 348 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 1.8E-37 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 Gene3D G3DSA:3.40.50.2300 29 156 1.1E-21 T 28-03-2018 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 Gene3D G3DSA:3.40.50.2300 157 282 5.2E-38 T 28-03-2018 AFA_RS09365 d4054015b0897c110d9d907a455657e1 374 SUPERFAMILY SSF53822 27 371 5.05E-91 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS07450 50a9ea460e468317eb72ee54b6c8cffa 340 Gene3D G3DSA:1.10.3470.10 7 321 5.5E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS07450 50a9ea460e468317eb72ee54b6c8cffa 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 21 316 2.9E-54 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS03770 1cc9929a76e084abcace198bb1c53ea1 263 Gene3D G3DSA:3.40.190.10 24 121 4.0E-25 T 28-03-2018 AFA_RS03770 1cc9929a76e084abcace198bb1c53ea1 263 SUPERFAMILY SSF53850 27 263 6.8E-87 T 28-03-2018 AFA_RS03770 1cc9929a76e084abcace198bb1c53ea1 263 PIRSF PIRSF002854 2 263 1.8E-106 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS03770 1cc9929a76e084abcace198bb1c53ea1 263 Gene3D G3DSA:3.40.190.10 122 263 5.5E-55 T 28-03-2018 AFA_RS03770 1cc9929a76e084abcace198bb1c53ea1 263 Pfam PF03180 NLPA lipoprotein 28 263 3.3E-100 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 517 7.6E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 Gene3D G3DSA:1.10.287.950 362 554 8.3E-50 T 28-03-2018 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 SUPERFAMILY SSF58104 270 555 4.19E-74 T 28-03-2018 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 324 353 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 507 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 33 58 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 81 96 6.6E-64 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 Pfam PF02203 Tar ligand binding domain homologue 33 182 4.9E-21 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 SMART SM00304 250 302 9.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 Gene3D G3DSA:1.20.120.30 51 222 4.5E-20 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 SMART SM00283 303 550 2.7E-89 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 Gene3D G3DSA:1.10.287.1060 279 361 5.9E-4 T 28-03-2018 AFA_RS05885 0a03904806c3b05f5a07b4830663b8f0 568 SUPERFAMILY SSF47170 54 216 1.57E-6 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 AFA_RS00800 57a5bc692e2a60778f1fb05b5c10380d 333 Gene3D G3DSA:3.40.190.10 1 194 3.7E-6 T 28-03-2018 AFA_RS00800 57a5bc692e2a60778f1fb05b5c10380d 333 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 42 315 8.7E-58 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS01675 847cd85aadfdc28aa04a87b3d25a9d8b 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 219 8.2E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01675 847cd85aadfdc28aa04a87b3d25a9d8b 223 Gene3D G3DSA:1.10.3720.10 3 223 1.5E-36 T 28-03-2018 AFA_RS01675 847cd85aadfdc28aa04a87b3d25a9d8b 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 113 3.6E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 AFA_RS01675 847cd85aadfdc28aa04a87b3d25a9d8b 223 SUPERFAMILY SSF161098 19 206 8.5E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS07790 ecadae8c68b6425e58d96186c2b0b019 424 Pfam PF12704 MacB-like periplasmic core domain 36 252 1.0E-17 T 28-03-2018 IPR025857 MacB-like periplasmic core domain AFA_RS07790 ecadae8c68b6425e58d96186c2b0b019 424 Pfam PF02687 FtsX-like permease family 310 417 1.4E-15 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFA_RS07790 ecadae8c68b6425e58d96186c2b0b019 424 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 423 4.0E-143 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 SUPERFAMILY SSF55961 162 440 1.41E-58 T 28-03-2018 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 Gene3D G3DSA:2.102.10.10 33 153 6.9E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 SUPERFAMILY SSF50022 13 161 1.57E-41 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 Gene3D G3DSA:3.90.380.10 154 443 5.1E-64 T 28-03-2018 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 Pfam PF00355 Rieske [2Fe-2S] domain 42 126 8.7E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 393 1.6E-12 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS00300 df8275a2a7c180c72ed6266da355873f 444 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 7.8E-32 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 AFA_RS12120 4f9243bee4a89132c32f76e9024e04ef 111 Pfam PF00816 H-NS histone family 10 96 4.5E-20 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 AFA_RS12120 4f9243bee4a89132c32f76e9024e04ef 111 Gene3D G3DSA:4.10.430.10 67 102 4.5E-13 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS12120 4f9243bee4a89132c32f76e9024e04ef 111 SMART SM00528 60 103 1.5E-9 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 AFA_RS12120 4f9243bee4a89132c32f76e9024e04ef 111 SUPERFAMILY SSF81273 65 103 1.53E-8 T 28-03-2018 AFA_RS17270 d8389b1112228e1a578ccb874557bdc5 144 Gene3D G3DSA:3.90.1590.10 1 142 1.5E-37 T 28-03-2018 AFA_RS17270 d8389b1112228e1a578ccb874557bdc5 144 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 23 111 1.5E-19 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFA_RS17270 d8389b1112228e1a578ccb874557bdc5 144 SUPERFAMILY SSF51316 2 133 8.37E-46 T 28-03-2018 IPR011057 Mss4-like AFA_RS07870 c361fdd626c446e9c2d88baaaf4b1af8 259 SUPERFAMILY SSF101082 32 227 1.15E-34 T 28-03-2018 IPR023220 Type IV secretion system, VirB5-domain AFA_RS07870 c361fdd626c446e9c2d88baaaf4b1af8 259 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 8 256 2.1E-62 T 28-03-2018 IPR014147 Type IV conjugative transfer protein TrbJ AFA_RS07870 c361fdd626c446e9c2d88baaaf4b1af8 259 Gene3D G3DSA:1.20.58.430 32 238 2.3E-47 T 28-03-2018 AFA_RS01020 18d0c1213d61925127ddafcaee20c02d 298 Gene3D G3DSA:3.40.50.10490 94 284 3.7E-21 T 28-03-2018 AFA_RS01020 18d0c1213d61925127ddafcaee20c02d 298 Pfam PF01380 SIS domain 131 256 2.8E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS01020 18d0c1213d61925127ddafcaee20c02d 298 Gene3D G3DSA:1.10.10.10 3 77 1.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01020 18d0c1213d61925127ddafcaee20c02d 298 SUPERFAMILY SSF53697 99 281 3.03E-18 T 28-03-2018 AFA_RS01020 18d0c1213d61925127ddafcaee20c02d 298 SUPERFAMILY SSF46689 2 76 1.65E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS14405 6223c39ed77dde93acda9b7a5cbebba4 284 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 262 5.1E-54 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFA_RS16695 2f31dd9c6ba04364f65f7fde0f34c802 247 Pfam PF10294 Lysine methyltransferase 65 200 2.3E-9 T 28-03-2018 IPR019410 Lysine methyltransferase AFA_RS16695 2f31dd9c6ba04364f65f7fde0f34c802 247 Gene3D G3DSA:3.40.50.150 16 234 1.3E-23 T 28-03-2018 AFA_RS16695 2f31dd9c6ba04364f65f7fde0f34c802 247 SUPERFAMILY SSF53335 65 229 1.01E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS00470 733e8d45cda1fbb98453304e1b0e5a83 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 84 6.7E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFA_RS00470 733e8d45cda1fbb98453304e1b0e5a83 87 SUPERFAMILY SSF143011 1 84 6.02E-18 T 28-03-2018 IPR035095 Toxin RelE-like domain AFA_RS00470 733e8d45cda1fbb98453304e1b0e5a83 87 Gene3D G3DSA:3.30.2310.20 1 87 4.6E-13 T 28-03-2018 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 SUPERFAMILY SSF81336 95 287 4.32E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 36 288 1.3E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 Pfam PF00119 ATP synthase A chain 42 286 1.1E-54 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 Hamap MF_01393 ATP synthase subunit a [atpB]. 14 293 14.15 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 Gene3D G3DSA:1.20.120.220 93 293 3.8E-41 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16630 faf9216662d4741deb33112fa1b2cd14 293 ProSitePatterns PS00449 ATP synthase a subunit signature. 216 225 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS17095 533cb97b342d5792a0b8e6f7172b53a0 258 Pfam PF02405 Permease MlaE 44 255 4.2E-75 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 AFA_RS17095 533cb97b342d5792a0b8e6f7172b53a0 258 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 32 257 4.5E-80 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 Gene3D G3DSA:3.40.50.300 342 597 1.5E-74 T 28-03-2018 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 SUPERFAMILY SSF52540 348 593 4.88E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 Pfam PF00005 ABC transporter 372 522 3.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 SMART SM00382 381 574 5.8E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 Pfam PF00664 ABC transporter transmembrane region 41 309 7.0E-47 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 SUPERFAMILY SSF90123 23 340 3.01E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 25 594 3.2E-241 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS05415 0fa02cb28a3aa5771fd1aa48c9cca096 597 Gene3D G3DSA:1.20.1560.10 5 341 2.1E-64 T 28-03-2018 AFA_RS00510 d29242183777e03576387a00c79eeb6e 274 SUPERFAMILY SSF53850 31 266 7.85E-60 T 28-03-2018 AFA_RS00510 d29242183777e03576387a00c79eeb6e 274 Gene3D G3DSA:3.40.190.10 30 127 7.9E-15 T 28-03-2018 AFA_RS00510 d29242183777e03576387a00c79eeb6e 274 Gene3D G3DSA:3.40.190.10 128 266 5.4E-35 T 28-03-2018 AFA_RS00510 d29242183777e03576387a00c79eeb6e 274 Pfam PF03180 NLPA lipoprotein 31 264 5.4E-66 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS11430 04e66ee16436e7f21e12afd0417a446d 398 SUPERFAMILY SSF103473 6 391 4.45E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS11430 04e66ee16436e7f21e12afd0417a446d 398 Pfam PF07690 Major Facilitator Superfamily 29 352 2.4E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS11430 04e66ee16436e7f21e12afd0417a446d 398 Gene3D G3DSA:1.20.1250.20 6 189 8.1E-15 T 28-03-2018 AFA_RS11430 04e66ee16436e7f21e12afd0417a446d 398 Gene3D G3DSA:1.20.1250.20 193 392 6.7E-18 T 28-03-2018 AFA_RS03700 f3ff223436ab10e19de5e274aed8e6f4 170 Pfam PF05258 Protein of unknown function (DUF721) 43 108 4.3E-9 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 SUPERFAMILY SSF54675 20 132 6.28E-31 T 28-03-2018 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 133 298 3.6E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 PIRSF PIRSF006250 26 299 1.3E-87 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 Gene3D G3DSA:3.20.20.70 159 289 1.5E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 44 131 1.1E-23 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 SUPERFAMILY SSF51690 133 298 1.41E-55 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 Gene3D G3DSA:3.90.1170.20 13 158 1.0E-38 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFA_RS06095 b701cbe41ed460ebc7aed13fdb84275f 299 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 33 298 1.4E-95 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AFA_RS14750 888b5014f2c5d647dd649d5dd70ca33d 467 Pfam PF00324 Amino acid permease 21 430 2.5E-104 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 AFA_RS14750 888b5014f2c5d647dd649d5dd70ca33d 467 PIRSF PIRSF006060 2 462 2.2E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AFA_RS14750 888b5014f2c5d647dd649d5dd70ca33d 467 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 AFA_RS12300 161de840bd1ccabc5ebe60bd44c0d65b 422 Pfam PF01610 Transposase 148 375 5.0E-59 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFA_RS12300 161de840bd1ccabc5ebe60bd44c0d65b 422 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 77 1.0E-6 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger AFA_RS12300 161de840bd1ccabc5ebe60bd44c0d65b 422 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 84 132 2.9E-10 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain AFA_RS04250 114efd79a6f7e59cdb5e2322afdde32f 241 Gene3D G3DSA:3.40.190.10 7 112 4.1E-14 T 28-03-2018 AFA_RS04250 114efd79a6f7e59cdb5e2322afdde32f 241 Gene3D G3DSA:3.40.190.10 113 194 8.5E-11 T 28-03-2018 AFA_RS04250 114efd79a6f7e59cdb5e2322afdde32f 241 SUPERFAMILY SSF53850 17 228 3.43E-31 T 28-03-2018 AFA_RS04250 114efd79a6f7e59cdb5e2322afdde32f 241 SMART SM00062 16 232 3.2E-18 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS04250 114efd79a6f7e59cdb5e2322afdde32f 241 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 17 228 1.7E-22 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 Gene3D G3DSA:3.40.50.80 309 437 1.6E-12 T 28-03-2018 AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 Pfam PF08022 FAD-binding domain 226 296 3.1E-9 T 28-03-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 SUPERFAMILY SSF63380 228 309 3.03E-17 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 SUPERFAMILY SSF52343 299 419 5.89E-14 T 28-03-2018 AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 Pfam PF01794 Ferric reductase like transmembrane component 43 172 2.4E-20 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain AFA_RS02350 d6f3198f4f0bb24b5f94a9887394bb8f 437 Gene3D G3DSA:2.40.30.10 210 307 1.5E-16 T 28-03-2018 AFA_RS15125 9e90e60ffdca7c08b7623f563cd9a2c4 350 SUPERFAMILY SSF144052 135 340 4.05E-16 T 28-03-2018 AFA_RS12755 3324a743f40c4ec4fe23615c03096ee0 484 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 471 3.3E-89 T 28-03-2018 IPR010352 Protein of unknown function DUF945 AFA_RS17415 56e799f6bee8a0e327584898518c8217 208 Gene3D G3DSA:3.40.50.850 1 208 7.5E-45 T 28-03-2018 AFA_RS17415 56e799f6bee8a0e327584898518c8217 208 Pfam PF00857 Isochorismatase family 14 165 9.5E-22 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS17415 56e799f6bee8a0e327584898518c8217 208 SUPERFAMILY SSF52499 4 202 9.94E-54 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS16500 86b8a825c5522376b8aba4bf7455ece7 174 Gene3D G3DSA:2.160.10.10 1 174 1.5E-41 T 28-03-2018 AFA_RS16500 86b8a825c5522376b8aba4bf7455ece7 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 6.5E-9 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS16500 86b8a825c5522376b8aba4bf7455ece7 174 SUPERFAMILY SSF51161 2 170 3.33E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 253 1.5E-99 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 Gene3D G3DSA:3.20.20.20 137 259 1.0E-48 T 28-03-2018 AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 Gene3D G3DSA:3.20.20.20 1 136 6.2E-57 T 28-03-2018 AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 SUPERFAMILY SSF51717 1 254 5.63E-100 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS04175 c5f732499f0d232fbaae0dbf45b21375 260 Pfam PF00809 Pterin binding enzyme 1 239 3.1E-86 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFA_RS07055 fa54bf98f2e918c1922067cdc95fca58 107 Pfam PF06356 Protein of unknown function (DUF1064) 20 80 5.3E-6 T 28-03-2018 IPR009414 Protein of unknown function DUF1064 AFA_RS12745 fa51aee64851a8d512f38f427391746d 257 Gene3D G3DSA:2.40.160.20 27 131 0.031 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS12745 fa51aee64851a8d512f38f427391746d 257 SUPERFAMILY SSF56935 74 224 2.34E-5 T 28-03-2018 AFA_RS12745 fa51aee64851a8d512f38f427391746d 257 Pfam PF06629 MltA-interacting protein MipA 33 257 7.2E-39 T 28-03-2018 IPR010583 MltA-interacting MipA AFA_RS12745 fa51aee64851a8d512f38f427391746d 257 Gene3D G3DSA:2.40.160.40 145 257 1.4E-6 T 28-03-2018 AFA_RS17660 49036ed2c237a8ab63e67e4f049b9cc9 100 Pfam PF01381 Helix-turn-helix 45 88 2.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS17660 49036ed2c237a8ab63e67e4f049b9cc9 100 Gene3D G3DSA:1.10.260.40 44 93 1.1E-8 T 28-03-2018 AFA_RS17660 49036ed2c237a8ab63e67e4f049b9cc9 100 SUPERFAMILY SSF47413 44 97 7.42E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS04960 af9414d819aff88e4320dd29c9f94b2d 431 PIRSF PIRSF006066 1 431 2.3E-104 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS04960 af9414d819aff88e4320dd29c9f94b2d 431 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 419 4.5E-78 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS04960 af9414d819aff88e4320dd29c9f94b2d 431 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 425 3.3E-95 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 412 1.7E-113 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 Pfam PF01546 Peptidase family M20/M25/M40 82 411 5.2E-27 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 SUPERFAMILY SSF53187 3 226 1.05E-83 T 28-03-2018 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 SUPERFAMILY SSF53187 342 414 1.05E-83 T 28-03-2018 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 PIRSF PIRSF001235 7 418 2.8E-137 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 Gene3D G3DSA:3.40.630.10 260 418 9.3E-20 T 28-03-2018 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 Gene3D G3DSA:3.40.630.10 6 259 8.9E-36 T 28-03-2018 AFA_RS01630 239b279541ce1d3727070acdb7d81e57 418 SUPERFAMILY SSF55031 216 334 6.73E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain AFA_RS00285 d9a0655ccaf5ac2a484249041018c593 342 Pfam PF00795 Carbon-nitrogen hydrolase 8 287 2.4E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00285 d9a0655ccaf5ac2a484249041018c593 342 Gene3D G3DSA:3.60.110.10 3 324 4.2E-61 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00285 d9a0655ccaf5ac2a484249041018c593 342 SUPERFAMILY SSF56317 5 310 5.49E-66 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00285 d9a0655ccaf5ac2a484249041018c593 342 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 Gene3D G3DSA:3.50.50.60 1 379 6.3E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 SUPERFAMILY SSF54373 206 300 1.33E-36 T 28-03-2018 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 54 4.7E-7 T 28-03-2018 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 438 540 6.7E-49 T 28-03-2018 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 1.8E-5 T 28-03-2018 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.8E-5 T 28-03-2018 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 SUPERFAMILY SSF51905 301 440 4.92E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 SUPERFAMILY SSF51905 1 204 4.92E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS12940 908cd8014f33dc26b9b56f942186a12f 542 SUPERFAMILY SSF54862 442 540 2.55E-27 T 28-03-2018 AFA_RS00380 f66c875395891294331a5b09aa2ae26f 530 SUPERFAMILY SSF51905 6 338 3.89E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00380 f66c875395891294331a5b09aa2ae26f 530 SUPERFAMILY SSF51905 495 529 3.89E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00380 f66c875395891294331a5b09aa2ae26f 530 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 64 2.0E-12 T 28-03-2018 AFA_RS00380 f66c875395891294331a5b09aa2ae26f 530 Gene3D G3DSA:3.50.50.60 2 530 1.8E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 Pfam PF12697 Alpha/beta hydrolase family 23 254 1.1E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.0E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 3.0E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 3.0E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 3.0E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 Gene3D G3DSA:3.40.50.1820 2 265 6.3E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS00135 06ddf6b08568c7f16d8af1d2dfb98365 266 SUPERFAMILY SSF53474 1 258 2.39E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01700 87649be29e0d18679d25021a52f68ead 290 Gene3D G3DSA:2.40.160.20 50 275 5.4E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS01700 87649be29e0d18679d25021a52f68ead 290 Pfam PF13557 Putative MetA-pathway of phenol degradation 58 286 2.8E-21 T 28-03-2018 IPR025737 MetA-pathway of phenol degradation, putative AFA_RS11440 761beda884e3cf6eaa7f98f84343c297 400 TIGRFAM TIGR00843 benE: benzoate transporter 23 394 4.3E-125 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS11440 761beda884e3cf6eaa7f98f84343c297 400 Pfam PF03594 Benzoate membrane transport protein 19 393 6.6E-141 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS07425 f3c64b411985dd81463802c9a7db8618 550 Gene3D G3DSA:1.20.120.570 425 536 9.9E-6 T 28-03-2018 AFA_RS07425 f3c64b411985dd81463802c9a7db8618 550 Pfam PF02470 MlaD protein 301 407 5.3E-11 T 28-03-2018 IPR003399 Mce/MlaD AFA_RS07425 f3c64b411985dd81463802c9a7db8618 550 Pfam PF02470 MlaD protein 173 233 3.3E-9 T 28-03-2018 IPR003399 Mce/MlaD AFA_RS07425 f3c64b411985dd81463802c9a7db8618 550 Pfam PF02470 MlaD protein 54 145 2.2E-10 T 28-03-2018 IPR003399 Mce/MlaD AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 SUPERFAMILY SSF53671 90 400 1.7E-87 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 Gene3D G3DSA:3.40.50.1370 231 403 9.0E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 172 1.0E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00101 Aspartate carbamoyltransferase signature 124 146 1.0E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00101 Aspartate carbamoyltransferase signature 380 394 1.0E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00101 Aspartate carbamoyltransferase signature 314 323 1.0E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00101 Aspartate carbamoyltransferase signature 217 234 1.0E-29 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 90 230 3.6E-42 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 242 397 2.2E-29 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 153 1.6E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 349 358 1.6E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 364 387 1.6E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 218 229 1.6E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 Gene3D G3DSA:3.40.50.1370 79 230 4.1E-49 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 134 141 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFA_RS11060 d06ace5eb55776b274f2d9c849de6d20 431 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 90 399 1.3E-88 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS02305 3cd27917e2f6a214e6e127d7cdec2e63 88 Gene3D G3DSA:1.10.1220.10 32 88 1.2E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS15315 50b460967ac1e8f474734791cfabf776 366 Gene3D G3DSA:3.20.20.70 2 366 7.1E-123 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS15315 50b460967ac1e8f474734791cfabf776 366 SUPERFAMILY SSF51395 3 365 2.87E-122 T 28-03-2018 AFA_RS15315 50b460967ac1e8f474734791cfabf776 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 343 1.0E-92 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFA_RS03000 8149d87ee83b54fb644fa21a87493db3 339 Pfam PF00535 Glycosyl transferase family 2 11 168 1.5E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFA_RS03000 8149d87ee83b54fb644fa21a87493db3 339 Gene3D G3DSA:3.90.550.10 2 200 9.0E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS03000 8149d87ee83b54fb644fa21a87493db3 339 SUPERFAMILY SSF53448 9 256 5.23E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 Pfam PF03193 RsgA GTPase 60 232 6.9E-48 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 SUPERFAMILY SSF52540 76 295 5.43E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 290 7.1E-60 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 SUPERFAMILY SSF50249 6 64 5.57E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 6 297 33.717 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 Gene3D G3DSA:2.40.50.140 1 62 4.5E-14 T 28-03-2018 AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 Gene3D G3DSA:3.40.50.300 72 232 9.1E-17 T 28-03-2018 AFA_RS11870 dfb0990ff29aa8b398a6c8a40a7dd11d 299 Gene3D G3DSA:1.10.40.50 234 299 3.7E-23 T 28-03-2018 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 SUPERFAMILY SSF56645 31 247 8.12E-40 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 Gene3D G3DSA:1.20.140.10 253 427 3.9E-18 T 28-03-2018 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 266 402 2.5E-12 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 144 239 9.6E-11 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 Gene3D G3DSA:2.40.110.10 141 250 2.1E-18 T 28-03-2018 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 PIRSF PIRSF016578 18 420 7.8E-35 T 28-03-2018 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 SUPERFAMILY SSF47203 257 402 7.57E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFA_RS00525 cfe0075b7524c6b0f6031ce117c0ad61 432 Gene3D G3DSA:1.10.540.10 28 134 1.1E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 SMART SM00388 225 294 1.7E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 SMART SM00387 338 447 6.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Gene3D G3DSA:1.10.287.130 196 277 2.1E-11 T 28-03-2018 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Pfam PF08521 Two-component sensor kinase N-terminal 15 148 1.7E-8 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 444 1.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 SUPERFAMILY SSF47384 208 293 1.55E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Gene3D G3DSA:3.30.565.10 278 447 6.6E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 6.2E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 6.2E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 444 6.2E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Gene3D G3DSA:1.20.5.1040 128 172 4.3E-4 T 28-03-2018 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Gene3D G3DSA:1.20.5.1040 1 59 2.1E-9 T 28-03-2018 AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 SUPERFAMILY SSF55874 286 445 2.88E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06370 7a807129eaebe411d965adaa0887ae73 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 293 7.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFA_RS06245 161a67accb465cf9221768608ea11420 442 Gene3D G3DSA:3.50.50.60 173 293 2.5E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06245 161a67accb465cf9221768608ea11420 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 46 150 5.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06245 161a67accb465cf9221768608ea11420 442 SUPERFAMILY SSF51905 165 293 9.5E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06245 161a67accb465cf9221768608ea11420 442 Gene3D G3DSA:3.50.50.60 34 172 2.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06245 161a67accb465cf9221768608ea11420 442 SUPERFAMILY SSF51905 293 374 1.8E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS06245 161a67accb465cf9221768608ea11420 442 SUPERFAMILY SSF51905 46 150 1.8E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS10680 b53c80bcc1dc0a91a2c4bd1af6c105ed 129 Gene3D G3DSA:3.10.450.50 2 126 6.5E-21 T 28-03-2018 AFA_RS10680 b53c80bcc1dc0a91a2c4bd1af6c105ed 129 Pfam PF12680 SnoaL-like domain 9 113 1.0E-13 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain AFA_RS10680 b53c80bcc1dc0a91a2c4bd1af6c105ed 129 SUPERFAMILY SSF54427 3 123 1.39E-22 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 8.9E-33 T 28-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 PRINTS PR00160 Glutaredoxin signature 47 60 1.3E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 PRINTS PR00160 Glutaredoxin signature 61 74 1.3E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 PRINTS PR00160 Glutaredoxin signature 4 22 1.3E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 SUPERFAMILY SSF52833 3 84 2.61E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 Gene3D G3DSA:3.40.30.10 1 85 7.2E-24 T 28-03-2018 AFA_RS16435 ada037566bebc59bbc4ac2ce815e225a 85 Pfam PF00462 Glutaredoxin 4 64 6.8E-17 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 7.8E-37 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 19.139 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 SUPERFAMILY SSF47928 3 107 1.7E-21 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 2.5E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 PRINTS PR00125 ATP synthase delta subunit signature 87 101 2.5E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 PRINTS PR00125 ATP synthase delta subunit signature 7 26 2.5E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 2.5E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 PRINTS PR00125 ATP synthase delta subunit signature 76 87 2.5E-21 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 7.9E-46 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS16615 2b0fba56a4279b067f4a93cf6c17d52b 179 Gene3D G3DSA:1.10.520.20 2 108 1.5E-25 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFA_RS12550 4d703ed8ce958cfbec4a7a4bae6df299 364 Gene3D G3DSA:3.40.50.1820 50 345 4.1E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS12550 4d703ed8ce958cfbec4a7a4bae6df299 364 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 178 190 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site AFA_RS12550 4d703ed8ce958cfbec4a7a4bae6df299 364 SUPERFAMILY SSF53474 95 332 2.68E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS12550 4d703ed8ce958cfbec4a7a4bae6df299 364 Pfam PF07859 alpha/beta hydrolase fold 111 310 2.7E-41 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 Pfam PF00005 ABC transporter 17 165 2.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 Gene3D G3DSA:3.40.50.300 1 239 6.1E-66 T 28-03-2018 AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 PIRSF PIRSF039085 1 243 1.2E-95 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 SMART SM00382 26 213 1.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS08480 a7d008c44327d7f1d1b0b8f9f4da3e16 244 SUPERFAMILY SSF52540 1 225 1.16E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 Pfam PF00107 Zinc-binding dehydrogenase 166 291 1.0E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 SUPERFAMILY SSF50129 1 160 1.22E-38 T 28-03-2018 IPR011032 GroES-like AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 Gene3D G3DSA:3.90.180.10 1 332 1.1E-73 T 28-03-2018 AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 SUPERFAMILY SSF51735 134 307 4.2E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 1.0E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFA_RS08980 bbcf212419c249c0f315c658c5c4242e 339 SMART SM00829 10 329 4.0E-16 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFA_RS16355 dddad8a9b69102a6c4419c9f86c92d0a 169 SUPERFAMILY SSF55804 4 150 3.01E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 AFA_RS16355 dddad8a9b69102a6c4419c9f86c92d0a 169 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 55 71 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain AFA_RS16355 dddad8a9b69102a6c4419c9f86c92d0a 169 Gene3D G3DSA:3.40.930.10 6 153 1.1E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 AFA_RS16355 dddad8a9b69102a6c4419c9f86c92d0a 169 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 14 151 3.6E-32 T 28-03-2018 IPR002178 PTS EIIA type-2 domain AFA_RS02950 3cb848fef8534fe8b2f02e93cbc18692 145 Gene3D G3DSA:3.40.1420.10 30 144 1.2E-26 T 28-03-2018 AFA_RS02950 3cb848fef8534fe8b2f02e93cbc18692 145 Pfam PF08816 Inhibitor of vertebrate lysozyme (Ivy) 39 137 9.5E-20 T 28-03-2018 AFA_RS02950 3cb848fef8534fe8b2f02e93cbc18692 145 SUPERFAMILY SSF89872 32 137 2.75E-16 T 28-03-2018 IPR014453 Inhibitor of vertebrate lysozyme GO:0042597|GO:0043086 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 7.8E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 SUPERFAMILY SSF52304 4 143 6.93E-62 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 142 6.0E-44 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 PIRSF PIRSF001399 1 144 3.6E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 Gene3D G3DSA:3.40.50.9100 1 144 1.4E-66 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 71.897 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS15655 7d1e55af387c1e293a95f90c67c062fe 144 Pfam PF01220 Dehydroquinase class II 5 141 5.5E-62 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 SUPERFAMILY SSF88697 14 179 1.39E-44 T 28-03-2018 IPR015947 PUA-like domain AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 Pfam PF01747 ATP-sulfurylase 184 390 1.1E-62 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 SUPERFAMILY SSF52374 196 389 3.85E-54 T 28-03-2018 AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 Gene3D G3DSA:3.10.400.10 13 192 3.6E-53 T 28-03-2018 AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 Pfam PF14306 PUA-like domain 14 175 1.2E-44 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFA_RS12430 fe18b037ffe4e8ec7abb1b38f366bcc9 569 Gene3D G3DSA:3.40.50.620 193 392 1.1E-61 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS15980 dfe836f95deb411dc22238360f6ed88d 154 SUPERFAMILY SSF54427 13 146 3.68E-24 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS15980 dfe836f95deb411dc22238360f6ed88d 154 Pfam PF12680 SnoaL-like domain 21 123 4.3E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain AFA_RS15980 dfe836f95deb411dc22238360f6ed88d 154 Gene3D G3DSA:3.10.450.50 7 134 1.3E-20 T 28-03-2018 AFA_RS02380 ff3a87dbd3f2088f15fa8dc035035c84 103 SUPERFAMILY SSF54909 4 96 1.29E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS02380 ff3a87dbd3f2088f15fa8dc035035c84 103 Pfam PF08803 Putative mono-oxygenase ydhR 4 99 5.2E-40 T 28-03-2018 IPR014910 Putative monooxygenase YdhR AFA_RS14765 d3b91a0ebf365edbded5e78f3aa414df 462 SMART SM01150 13 409 4.3E-208 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 AFA_RS14765 d3b91a0ebf365edbded5e78f3aa414df 462 Pfam PF07063 Domain of unknown function (DUF1338) 11 409 8.9E-117 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 AFA_RS12855 0a8bbec43a40661745640853a70403a5 138 PIRSF PIRSF004638 1 138 1.4E-50 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 AFA_RS12855 0a8bbec43a40661745640853a70403a5 138 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 138 4.4E-48 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 AFA_RS16245 ca98ec47303da1cf03074ae72e4381ae 339 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 300 4.0E-82 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFA_RS16245 ca98ec47303da1cf03074ae72e4381ae 339 SMART SM00797 24 317 3.1E-114 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFA_RS16245 ca98ec47303da1cf03074ae72e4381ae 339 SUPERFAMILY SSF50891 193 307 4.93E-8 T 28-03-2018 IPR029000 Cyclophilin-like domain AFA_RS16245 ca98ec47303da1cf03074ae72e4381ae 339 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 324 4.2E-85 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFA_RS10595 4c3f7d95734ef2c0846e73cee175aa0a 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 16 200 1.3E-52 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFA_RS10595 4c3f7d95734ef2c0846e73cee175aa0a 213 SMART SM01207 15 201 5.4E-89 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFA_RS10595 4c3f7d95734ef2c0846e73cee175aa0a 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 12 209 20.998 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFA_RS10595 4c3f7d95734ef2c0846e73cee175aa0a 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 10 210 3.3E-62 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFA_RS06685 dd9313784603d7428bf7a1cf9c5457ed 93 Gene3D G3DSA:2.30.130.30 1 91 1.7E-5 T 28-03-2018 AFA_RS16215 5b9fa037125e9ff826bc06303f004953 330 SUPERFAMILY SSF54427 204 325 1.4E-13 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS16215 5b9fa037125e9ff826bc06303f004953 330 SMART SM00978 196 323 3.5E-31 T 28-03-2018 IPR007379 Tim44-like domain AFA_RS16215 5b9fa037125e9ff826bc06303f004953 330 Pfam PF04280 Tim44-like domain 205 323 8.8E-13 T 28-03-2018 IPR007379 Tim44-like domain AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 30 46 9.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 46 58 9.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 16 30 9.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 SUPERFAMILY SSF46894 7 71 1.09E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 Gene3D G3DSA:1.10.10.10 2 78 4.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 ProSitePatterns PS00622 LuxR-type HTH domain signature. 30 57 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 Pfam PF00196 Bacterial regulatory proteins, luxR family 15 69 2.2E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS16090 a910cadc1081b17c59507932ce7ab9d3 91 SMART SM00421 13 70 9.6E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFA_RS14470 cef3a1c06ba047f08702503adbd8b92e 92 SUPERFAMILY SSF47592 12 91 1.61E-28 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 AFA_RS14470 cef3a1c06ba047f08702503adbd8b92e 92 Pfam PF02201 SWIB/MDM2 domain 19 91 8.4E-29 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 AFA_RS14470 cef3a1c06ba047f08702503adbd8b92e 92 Gene3D G3DSA:1.10.245.10 1 92 6.9E-30 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 AFA_RS14470 cef3a1c06ba047f08702503adbd8b92e 92 SMART SM00151 17 92 3.1E-33 T 28-03-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858 AFA_RS05400 afdfa3c2d39336ff3c8180c6a69c9251 86 Pfam PF03692 Putative zinc- or iron-chelating domain 3 60 5.8E-6 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFA_RS17610 720dad9f5e7a8eb6591416be4c68782d 283 Gene3D G3DSA:3.60.10.10 2 283 5.8E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS17610 720dad9f5e7a8eb6591416be4c68782d 283 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 273 3.9E-14 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS17610 720dad9f5e7a8eb6591416be4c68782d 283 SUPERFAMILY SSF56219 228 280 8.51E-42 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS17610 720dad9f5e7a8eb6591416be4c68782d 283 SUPERFAMILY SSF56219 4 189 8.51E-42 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 SMART SM00934 17 256 2.1E-47 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 SUPERFAMILY SSF51366 3 267 9.82E-76 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 Gene3D G3DSA:3.20.20.70 2 271 1.8E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 16 247 1.8E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 269 34.128 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFA_RS14830 0cda9af948ec73a5a857a15a4989000a 275 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 251 3.3E-71 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 PIRSF PIRSF002825 1 332 9.4E-93 T 28-03-2018 IPR026045 Ferric binding protein AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 Pfam PF13343 Bacterial extracellular solute-binding protein 73 313 2.7E-32 T 28-03-2018 AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 Gene3D G3DSA:3.40.190.10 140 287 1.0E-36 T 28-03-2018 AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 Gene3D G3DSA:3.40.190.10 15 139 3.8E-8 T 28-03-2018 AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 SUPERFAMILY SSF53850 21 329 3.71E-75 T 28-03-2018 AFA_RS11370 e95c7c1f34a80b10590d37cc93827a1b 339 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 4 336 9.9E-157 T 28-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative AFA_RS01095 5d8cbd090048664571303c3e491f7ef8 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 294 2.3E-31 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS01095 5d8cbd090048664571303c3e491f7ef8 309 Gene3D G3DSA:1.10.3470.10 1 296 2.9E-38 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS06335 12c3665a7daeeb465dcee373cd62b773 423 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 1 306 2.9E-67 T 28-03-2018 IPR014150 Conjugal transfer, TrbL AFA_RS06335 12c3665a7daeeb465dcee373cd62b773 423 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 256 6.0E-54 T 28-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 AFA_RS05705 2b42f67ebf12f03d2a8f510503eb8f62 150 Pfam PF05154 TM2 domain 87 134 1.8E-13 T 28-03-2018 IPR007829 TM2 domain AFA_RS05165 6bf96fdbf2619bdf717e26fb260fc987 302 Pfam PF00892 EamA-like transporter family 142 272 2.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS05165 6bf96fdbf2619bdf717e26fb260fc987 302 Pfam PF00892 EamA-like transporter family 4 132 1.5E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS05165 6bf96fdbf2619bdf717e26fb260fc987 302 SUPERFAMILY SSF103481 186 277 9.55E-12 T 28-03-2018 AFA_RS05165 6bf96fdbf2619bdf717e26fb260fc987 302 SUPERFAMILY SSF103481 39 135 1.57E-12 T 28-03-2018 AFA_RS14090 9f1819faac81e6b2fc99e96e7cd196a7 240 Pfam PF00117 Glutamine amidotransferase class-I 27 182 1.1E-16 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS14090 9f1819faac81e6b2fc99e96e7cd196a7 240 SUPERFAMILY SSF52317 25 232 5.0E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS14090 9f1819faac81e6b2fc99e96e7cd196a7 240 Gene3D G3DSA:3.40.50.880 1 229 1.1E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS00640 0de4b303f9ad529a79a67184ac79ab3b 390 SUPERFAMILY SSF140931 93 285 7.06E-28 T 28-03-2018 IPR003812 Fido domain AFA_RS00640 0de4b303f9ad529a79a67184ac79ab3b 390 Pfam PF02661 Fic/DOC family 113 215 1.6E-14 T 28-03-2018 IPR003812 Fido domain AFA_RS00640 0de4b303f9ad529a79a67184ac79ab3b 390 Gene3D G3DSA:1.10.10.10 309 358 9.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00640 0de4b303f9ad529a79a67184ac79ab3b 390 Gene3D G3DSA:1.10.3290.10 18 298 1.0E-40 T 28-03-2018 IPR003812 Fido domain AFA_RS17030 ac264943026018d93b04a7f859184866 388 Gene3D G3DSA:3.30.1950.10 86 167 7.8E-17 T 28-03-2018 AFA_RS17030 ac264943026018d93b04a7f859184866 388 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 172 6.7E-20 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AFA_RS17030 ac264943026018d93b04a7f859184866 388 Gene3D G3DSA:3.10.560.10 168 253 1.8E-16 T 28-03-2018 AFA_RS17030 ac264943026018d93b04a7f859184866 388 Gene3D G3DSA:3.10.560.10 254 360 3.0E-17 T 28-03-2018 AFA_RS00875 cb3c5460d2a8c8d5375eccd7ffbf6c20 82 Pfam PF04226 Transglycosylase associated protein 33 80 7.0E-16 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 AFA_RS11945 038a8117ecb297416fc46987f7408031 415 Gene3D G3DSA:1.25.40.10 207 333 1.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11945 038a8117ecb297416fc46987f7408031 415 SUPERFAMILY SSF48452 40 176 3.48E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS11945 038a8117ecb297416fc46987f7408031 415 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 413 32.389 T 28-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 AFA_RS11945 038a8117ecb297416fc46987f7408031 415 Gene3D G3DSA:1.25.40.10 19 206 2.2E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13555 50710c79b51ddd5c1c58cf649a7be35a 255 Pfam PF01713 Smr domain 167 244 2.7E-21 T 28-03-2018 IPR002625 Smr domain AFA_RS13555 50710c79b51ddd5c1c58cf649a7be35a 255 SUPERFAMILY SSF160443 166 246 2.35E-17 T 28-03-2018 IPR002625 Smr domain AFA_RS13555 50710c79b51ddd5c1c58cf649a7be35a 255 SMART SM00463 164 248 1.6E-11 T 28-03-2018 IPR002625 Smr domain AFA_RS09955 4fe858dd8bf43556b6a51677c23d343e 161 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 157 3.8E-54 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp AFA_RS09955 4fe858dd8bf43556b6a51677c23d343e 161 Pfam PF05638 Type VI secretion system effector, Hcp 6 146 1.0E-35 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp AFA_RS09955 4fe858dd8bf43556b6a51677c23d343e 161 SUPERFAMILY SSF141452 3 157 1.7E-39 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp AFA_RS09955 4fe858dd8bf43556b6a51677c23d343e 161 Gene3D G3DSA:2.30.110.20 1 160 3.0E-47 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp AFA_RS06090 2efaea4328233433a693f3e63ac796fe 314 SUPERFAMILY SSF55811 15 138 5.88E-8 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 AFA_RS06090 2efaea4328233433a693f3e63ac796fe 314 SUPERFAMILY SSF46785 230 300 6.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS06090 2efaea4328233433a693f3e63ac796fe 314 Gene3D G3DSA:3.90.79.10 2 239 3.1E-28 T 28-03-2018 AFA_RS06090 2efaea4328233433a693f3e63ac796fe 314 PIRSF PIRSF019423 2 312 6.4E-138 T 28-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein AFA_RS06090 2efaea4328233433a693f3e63ac796fe 314 Gene3D G3DSA:1.10.10.10 240 295 8.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08360 310411972751fc95f1bf8691893052ae 267 Pfam PF01168 Alanine racemase, N-terminal domain 42 250 3.5E-24 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFA_RS08360 310411972751fc95f1bf8691893052ae 267 PIRSF PIRSF004848 14 256 2.6E-73 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein AFA_RS08360 310411972751fc95f1bf8691893052ae 267 Gene3D G3DSA:3.20.20.10 10 256 3.7E-64 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS08360 310411972751fc95f1bf8691893052ae 267 SUPERFAMILY SSF51419 16 248 1.83E-75 T 28-03-2018 IPR029066 PLP-binding barrel AFA_RS08360 310411972751fc95f1bf8691893052ae 267 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 24 250 5.5E-60 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein AFA_RS01860 92bccb1f8bec0012dbd28db493b2e7d5 165 SUPERFAMILY SSF55298 48 157 3.46E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS01860 92bccb1f8bec0012dbd28db493b2e7d5 165 Pfam PF01042 Endoribonuclease L-PSP 49 154 7.8E-28 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family AFA_RS01860 92bccb1f8bec0012dbd28db493b2e7d5 165 Gene3D G3DSA:3.30.1330.40 46 165 4.9E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS10740 3ba166382b01ad184c70042e0ef5ad6d 250 Gene3D G3DSA:3.40.50.880 16 233 2.3E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS10740 3ba166382b01ad184c70042e0ef5ad6d 250 SUPERFAMILY SSF52317 31 202 5.18E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS10740 3ba166382b01ad184c70042e0ef5ad6d 250 Pfam PF00117 Glutamine amidotransferase class-I 27 191 2.0E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase AFA_RS04165 d6b19bbdc8ed4d287f0a851dabbcb1db 212 SUPERFAMILY SSF53335 3 211 3.57E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS04165 d6b19bbdc8ed4d287f0a851dabbcb1db 212 Gene3D G3DSA:3.40.50.150 1 212 2.3E-47 T 28-03-2018 AFA_RS04165 d6b19bbdc8ed4d287f0a851dabbcb1db 212 PIRSF PIRSF005461 1 212 4.7E-64 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 AFA_RS04165 d6b19bbdc8ed4d287f0a851dabbcb1db 212 Pfam PF01728 FtsJ-like methyltransferase 28 208 7.1E-50 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFA_RS04165 d6b19bbdc8ed4d287f0a851dabbcb1db 212 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 210 27.979 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 AFA_RS01165 4458c05cd7eb7586fe90c821910abecd 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 8.4E-98 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS01165 4458c05cd7eb7586fe90c821910abecd 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 7.8E-94 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS01165 4458c05cd7eb7586fe90c821910abecd 427 PIRSF PIRSF006066 1 427 3.7E-93 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 Gene3D G3DSA:3.40.50.300 652 861 0.0014 T 28-03-2018 AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 SUPERFAMILY SSF52540 1 112 9.18E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 SUPERFAMILY SSF52540 777 855 9.18E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 SUPERFAMILY SSF52540 246 256 9.18E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 Gene3D G3DSA:3.40.50.300 1 266 9.5E-21 T 28-03-2018 AFA_RS09280 4b245106c6340be60c62c400b55c2c91 873 Pfam PF13514 AAA domain 1 50 4.8E-6 T 28-03-2018 AFA_RS16555 d77d67ef3ff91468f9be8394527ac109 442 Pfam PF02397 Bacterial sugar transferase 254 436 8.6E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase AFA_RS16555 d77d67ef3ff91468f9be8394527ac109 442 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 185 441 4.3E-95 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFA_RS05520 0b4df959d8cf541ce30abd4110c0eb83 306 SUPERFAMILY SSF51556 24 300 3.64E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS05520 0b4df959d8cf541ce30abd4110c0eb83 306 Pfam PF04909 Amidohydrolase 29 300 1.2E-46 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS05520 0b4df959d8cf541ce30abd4110c0eb83 306 Gene3D G3DSA:3.20.20.140 2 304 4.9E-45 T 28-03-2018 AFA_RS14130 0def583ee95b05fae79a324bc37ccd2b 229 PIRSF PIRSF036382 26 218 3.0E-41 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator AFA_RS14130 0def583ee95b05fae79a324bc37ccd2b 229 SMART SM01012 156 211 3.7E-15 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 AFA_RS14130 0def583ee95b05fae79a324bc37ccd2b 229 SUPERFAMILY SSF52172 29 211 1.07E-35 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS14130 0def583ee95b05fae79a324bc37ccd2b 229 Pfam PF03861 ANTAR domain 159 211 6.0E-14 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 AFA_RS14130 0def583ee95b05fae79a324bc37ccd2b 229 Gene3D G3DSA:1.10.10.10 160 213 5.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS01005 7d44d9afd0445935baeeb6a6b2350d08 448 Gene3D G3DSA:1.20.5.340 128 279 1.1E-13 T 28-03-2018 AFA_RS01005 7d44d9afd0445935baeeb6a6b2350d08 448 Pfam PF02646 RmuC family 118 412 3.4E-87 T 28-03-2018 IPR003798 DNA recombination RmuC AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 SUPERFAMILY SSF53383 1 396 7.17E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 Gene3D G3DSA:3.40.640.10 76 299 1.4E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 Gene3D G3DSA:3.90.1150.10 301 396 1.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 Pfam PF00155 Aminotransferase class I and II 27 392 3.4E-81 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 Gene3D G3DSA:3.90.1150.10 1 75 2.0E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 PRINTS PR00799 Aspartate aminotransferase signature 273 298 6.9E-37 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 PRINTS PR00799 Aspartate aminotransferase signature 206 218 6.9E-37 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 PRINTS PR00799 Aspartate aminotransferase signature 341 359 6.9E-37 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS17745 a276a483a5571393b80866b99e0ee733 397 PRINTS PR00799 Aspartate aminotransferase signature 175 194 6.9E-37 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AFA_RS14450 301897459d28a4ebf563b34f50c99ea0 319 SUPERFAMILY SSF53686 7 314 1.22E-89 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS14450 301897459d28a4ebf563b34f50c99ea0 319 PIRSF PIRSF006278 10 318 3.8E-6 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AFA_RS14450 301897459d28a4ebf563b34f50c99ea0 319 Gene3D G3DSA:3.40.50.1100 2 117 2.5E-23 T 28-03-2018 AFA_RS14450 301897459d28a4ebf563b34f50c99ea0 319 Gene3D G3DSA:3.40.50.1100 118 319 3.3E-47 T 28-03-2018 AFA_RS14450 301897459d28a4ebf563b34f50c99ea0 319 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 306 1.1E-73 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS05975 f9a7c3f2c1cb224afccc84fc57fe929c 429 Pfam PF02120 Flagellar hook-length control protein FliK 344 418 5.6E-11 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 Gene3D G3DSA:3.50.50.60 1 361 2.8E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 294 307 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 SUPERFAMILY SSF51905 3 170 4.96E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 SUPERFAMILY SSF51905 276 390 4.96E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.0E-15 T 28-03-2018 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.0E-15 T 28-03-2018 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.0E-15 T 28-03-2018 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.0E-15 T 28-03-2018 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 389 2.8E-96 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AFA_RS01390 6f2931e085835faa5af8fb87a59c850d 397 Pfam PF01494 FAD binding domain 144 339 2.5E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS07325 6a01ad9565b55f0bcd61a7540ade2810 104 Pfam PF12112 Protein of unknown function (DUF3579) 6 91 1.6E-37 T 28-03-2018 IPR021969 Protein of unknown function DUF3579 AFA_RS00280 2e7ed16f31c62ef488f9d2512a0d55a8 307 Gene3D G3DSA:3.90.850.10 49 307 3.6E-76 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS00280 2e7ed16f31c62ef488f9d2512a0d55a8 307 SUPERFAMILY SSF56529 78 302 1.31E-70 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS00280 2e7ed16f31c62ef488f9d2512a0d55a8 307 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 300 2.2E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS07440 3ef27a9713af2cc38b30c58c069dbc67 385 Gene3D G3DSA:3.40.50.2300 26 234 3.6E-50 T 28-03-2018 AFA_RS07440 3ef27a9713af2cc38b30c58c069dbc67 385 Gene3D G3DSA:3.40.50.2300 235 360 1.1E-8 T 28-03-2018 AFA_RS07440 3ef27a9713af2cc38b30c58c069dbc67 385 SUPERFAMILY SSF53822 31 378 1.04E-87 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS07440 3ef27a9713af2cc38b30c58c069dbc67 385 Pfam PF13458 Periplasmic binding protein 32 373 2.9E-60 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS02945 757867cc93850c66ee95f38ab7af5518 64 Pfam PF00403 Heavy-metal-associated domain 3 59 3.5E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS02945 757867cc93850c66ee95f38ab7af5518 64 SUPERFAMILY SSF55008 2 62 5.76E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS02945 757867cc93850c66ee95f38ab7af5518 64 Gene3D G3DSA:3.30.70.100 1 61 3.3E-14 T 28-03-2018 AFA_RS09795 cf8153fddca0d6eac3b1af2dbabcc5bb 232 Pfam PF12101 Protein of unknown function (DUF3577) 6 145 8.0E-43 T 28-03-2018 IPR021960 Protein of unknown function DUF3577 AFA_RS12630 625b98f2e66c8d8c25e6334dad4b8355 185 Gene3D G3DSA:3.40.630.30 25 185 1.1E-27 T 28-03-2018 AFA_RS12630 625b98f2e66c8d8c25e6334dad4b8355 185 SUPERFAMILY SSF55729 15 146 6.32E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS12630 625b98f2e66c8d8c25e6334dad4b8355 185 Pfam PF00583 Acetyltransferase (GNAT) family 54 145 2.3E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS12630 625b98f2e66c8d8c25e6334dad4b8355 185 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 28 182 1.3E-62 T 28-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 AFA_RS11225 873b7337d74ae5b6cd947e1a36666928 125 Gene3D G3DSA:1.10.760.10 25 125 3.8E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11225 873b7337d74ae5b6cd947e1a36666928 125 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 117 4.0E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11225 873b7337d74ae5b6cd947e1a36666928 125 SUPERFAMILY SSF46626 30 121 4.36E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 Gene3D G3DSA:1.10.357.10 83 222 4.5E-20 T 28-03-2018 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 SUPERFAMILY SSF48498 80 211 3.78E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 3.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 Gene3D G3DSA:1.10.260.40 39 82 7.7E-6 T 28-03-2018 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 202 1.7E-8 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 SUPERFAMILY SSF46689 6 77 1.65E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS10570 4e85f6abcf88c8db189b666aa6ae2c61 222 Gene3D G3DSA:1.10.10.60 2 38 2.8E-6 T 28-03-2018 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 25 30 - T 28-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 Gene3D G3DSA:3.40.50.150 1 321 3.9E-57 T 28-03-2018 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 SUPERFAMILY SSF53335 230 308 4.05E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 SUPERFAMILY SSF53335 3 164 4.05E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 245 262 2.0E-26 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 58 78 2.0E-26 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 20 34 2.0E-26 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 287 307 2.0E-26 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 264 282 2.0E-26 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 AFA_RS06690 ba495646a4d4cd16ea50b142652fc4fd 324 Pfam PF01555 DNA methylase 22 300 8.5E-55 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFA_RS07365 eded41d699453088521b44b9e2ceaab8 359 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 10 349 35.896 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AFA_RS07365 eded41d699453088521b44b9e2ceaab8 359 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 22 340 5.7E-95 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AFA_RS07365 eded41d699453088521b44b9e2ceaab8 359 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 31 336 5.1E-68 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AFA_RS07365 eded41d699453088521b44b9e2ceaab8 359 SUPERFAMILY SSF52540 55 193 3.67E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS07365 eded41d699453088521b44b9e2ceaab8 359 Gene3D G3DSA:3.40.50.300 55 227 5.5E-5 T 28-03-2018 AFA_RS06655 c7a85cb8c80e193c1b3660d08d285dfa 133 SUPERFAMILY SSF54427 34 132 1.46E-31 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS06655 c7a85cb8c80e193c1b3660d08d285dfa 133 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 7 131 26.645 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 AFA_RS06655 c7a85cb8c80e193c1b3660d08d285dfa 133 Gene3D G3DSA:3.10.450.50 9 133 4.9E-42 T 28-03-2018 AFA_RS00600 569baf6c340b3a22f6fec48f32d1c2e0 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 421 1.6E-93 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS00600 569baf6c340b3a22f6fec48f32d1c2e0 433 PIRSF PIRSF006066 1 433 8.1E-118 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS00600 569baf6c340b3a22f6fec48f32d1c2e0 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 427 2.7E-98 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 2.8E-256 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.819 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 Gene3D G3DSA:3.50.7.10 186 373 1.5E-97 T 28-03-2018 IPR027409 GroEL-like apical domain AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 2.9E-97 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 SUPERFAMILY SSF52029 184 376 7.18E-84 T 28-03-2018 IPR027409 GroEL-like apical domain AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 Gene3D G3DSA:1.10.560.10 1 185 2.6E-41 T 28-03-2018 IPR027413 GroEL-like equatorial domain AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 PRINTS PR00298 60kDa chaperonin signature 398 419 9.1E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 PRINTS PR00298 60kDa chaperonin signature 83 110 9.1E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 PRINTS PR00298 60kDa chaperonin signature 268 291 9.1E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 PRINTS PR00298 60kDa chaperonin signature 27 53 9.1E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 PRINTS PR00298 60kDa chaperonin signature 350 375 9.1E-75 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 SUPERFAMILY SSF48592 406 521 1.5E-76 T 28-03-2018 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 SUPERFAMILY SSF48592 7 134 1.5E-76 T 28-03-2018 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 SUPERFAMILY SSF54849 137 203 8.7E-25 T 28-03-2018 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFA_RS14820 56231ae1f9c48b064f96106edad14f8d 548 Gene3D G3DSA:1.10.560.10 374 516 1.7E-26 T 28-03-2018 IPR027413 GroEL-like equatorial domain AFA_RS17945 f931b39c13753577164cbd62298ba90b 128 SUPERFAMILY SSF54913 23 126 2.52E-33 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFA_RS17945 f931b39c13753577164cbd62298ba90b 128 Pfam PF03091 CutA1 divalent ion tolerance protein 27 123 9.5E-30 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 AFA_RS17945 f931b39c13753577164cbd62298ba90b 128 Gene3D G3DSA:3.30.70.120 19 126 8.6E-33 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFA_RS18090 071103d72083dd0b1df449e7f907e3c7 505 Gene3D G3DSA:1.20.1600.10 32 447 6.3E-52 T 28-03-2018 AFA_RS18090 071103d72083dd0b1df449e7f907e3c7 505 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 43 441 4.6E-80 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 AFA_RS18090 071103d72083dd0b1df449e7f907e3c7 505 Pfam PF02321 Outer membrane efflux protein 261 437 5.1E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS18090 071103d72083dd0b1df449e7f907e3c7 505 Pfam PF02321 Outer membrane efflux protein 47 228 8.1E-15 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS18090 071103d72083dd0b1df449e7f907e3c7 505 SUPERFAMILY SSF56954 20 438 6.54E-73 T 28-03-2018 AFA_RS04830 1f2c63998f817cac09a44e39cd47b558 271 Pfam PF13560 Helix-turn-helix domain 10 89 1.8E-16 T 28-03-2018 AFA_RS04830 1f2c63998f817cac09a44e39cd47b558 271 SMART SM00530 14 86 6.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS04830 1f2c63998f817cac09a44e39cd47b558 271 SUPERFAMILY SSF47413 34 84 7.16E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS04830 1f2c63998f817cac09a44e39cd47b558 271 Gene3D G3DSA:1.10.260.40 1 96 4.8E-13 T 28-03-2018 AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 Pfam PF00482 Type II secretion system (T2SS), protein F 269 391 9.5E-26 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 Pfam PF00482 Type II secretion system (T2SS), protein F 67 189 4.7E-30 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 364 378 3.1E-29 T 28-03-2018 IPR003004 GspF/PilC family AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 62 74 3.1E-29 T 28-03-2018 IPR003004 GspF/PilC family AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 161 189 3.1E-29 T 28-03-2018 IPR003004 GspF/PilC family AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 380 399 3.1E-29 T 28-03-2018 IPR003004 GspF/PilC family AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 Gene3D G3DSA:1.10.357.10 78 153 8.1E-4 T 28-03-2018 AFA_RS14240 ded82b8d3b4e69635141c4ed5d1ea1e0 400 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 399 1.5E-145 T 28-03-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 AFA_RS08110 ff83ef504e3d41b308db4234ec404084 178 Pfam PF07987 Domain of unkown function (DUF1775) 26 174 3.3E-48 T 28-03-2018 IPR012533 YcnI-like AFA_RS02360 78c3523852716807a1d2859e30de3dd0 330 PIRSF PIRSF017082 1 330 1.1E-81 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS02360 78c3523852716807a1d2859e30de3dd0 330 SUPERFAMILY SSF53850 115 293 3.11E-9 T 28-03-2018 AFA_RS02360 78c3523852716807a1d2859e30de3dd0 330 Gene3D G3DSA:3.40.190.10 136 299 1.4E-9 T 28-03-2018 AFA_RS02360 78c3523852716807a1d2859e30de3dd0 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 3.5E-81 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS11425 1d14f6bfbcbd0ec24d1ef80255218291 390 SUPERFAMILY SSF103473 7 386 5.75E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS11425 1d14f6bfbcbd0ec24d1ef80255218291 390 Gene3D G3DSA:1.20.1250.20 200 387 6.8E-18 T 28-03-2018 AFA_RS11425 1d14f6bfbcbd0ec24d1ef80255218291 390 Pfam PF07690 Major Facilitator Superfamily 20 308 9.9E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS11425 1d14f6bfbcbd0ec24d1ef80255218291 390 Gene3D G3DSA:1.20.1250.20 2 199 1.3E-29 T 28-03-2018 AFA_RS12040 a21f14720c5014f5a2832788efb3f87f 271 Gene3D G3DSA:2.40.160.20 214 270 5.4E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS12040 a21f14720c5014f5a2832788efb3f87f 271 Gene3D G3DSA:2.40.160.20 41 213 8.4E-6 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AFA_RS12040 a21f14720c5014f5a2832788efb3f87f 271 SUPERFAMILY SSF103515 122 248 3.14E-7 T 28-03-2018 IPR005546 Autotransporter beta-domain AFA_RS17305 4079c6bc0e37b3d4fdf8983570c50d9b 276 PIRSF PIRSF006241 1 258 5.0E-63 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 AFA_RS17305 4079c6bc0e37b3d4fdf8983570c50d9b 276 Gene3D G3DSA:3.20.20.150 1 257 4.6E-42 T 28-03-2018 AFA_RS17305 4079c6bc0e37b3d4fdf8983570c50d9b 276 Pfam PF01261 Xylose isomerase-like TIM barrel 20 207 5.7E-22 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFA_RS17305 4079c6bc0e37b3d4fdf8983570c50d9b 276 SUPERFAMILY SSF51658 1 256 2.07E-57 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFA_RS17340 8f8aeda7e2ceaeb37c4173ef4eea6a97 125 SUPERFAMILY SSF55298 8 124 5.03E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS17340 8f8aeda7e2ceaeb37c4173ef4eea6a97 125 Pfam PF01042 Endoribonuclease L-PSP 15 123 1.1E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family AFA_RS17340 8f8aeda7e2ceaeb37c4173ef4eea6a97 125 Gene3D G3DSA:3.30.1330.40 7 124 6.0E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS08380 cff3b947e7592b4a38ac1b5288f43ae8 555 SMART SM00990 437 551 3.2E-39 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 AFA_RS08380 cff3b947e7592b4a38ac1b5288f43ae8 555 Pfam PF08774 VRR-NUC domain 441 550 1.4E-29 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 AFA_RS08380 cff3b947e7592b4a38ac1b5288f43ae8 555 Gene3D G3DSA:1.25.40.10 195 446 0.0014 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 Gene3D G3DSA:3.30.450.40 178 337 7.4E-43 T 28-03-2018 IPR029016 GAF domain-like AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 324 25.916 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 7 70 5.0E-7 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 PIRSF PIRSF005485 1 335 6.5E-105 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 330 6.3E-92 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 SUPERFAMILY SSF55781 68 333 1.33E-60 T 28-03-2018 IPR029016 GAF domain-like AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 Gene3D G3DSA:1.10.10.10 1 82 8.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 SUPERFAMILY SSF46785 1 77 9.52E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13765 b16a29de6a7ba5907dc83c3116f94557 337 Pfam PF01628 HrcA protein C terminal domain 101 317 1.2E-57 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 AFA_RS06215 6027ba9d0eaadcb76b201c7dababdb19 160 Pfam PF00857 Isochorismatase family 78 149 6.8E-10 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS06215 6027ba9d0eaadcb76b201c7dababdb19 160 SUPERFAMILY SSF52499 1 157 6.93E-18 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS06215 6027ba9d0eaadcb76b201c7dababdb19 160 Gene3D G3DSA:3.40.50.850 1 160 2.2E-15 T 28-03-2018 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 Gene3D G3DSA:3.40.605.10 2 267 1.2E-85 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 Pfam PF00171 Aldehyde dehydrogenase family 24 486 9.7E-138 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 490 1.2E-199 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 Gene3D G3DSA:3.40.309.10 268 468 2.3E-58 T 28-03-2018 AFA_RS11055 6149831f26ecc73d17985618639d001c 506 SUPERFAMILY SSF53720 6 489 3.14E-145 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS07630 2a0e43c3e8199f7b97ad8fd5bf0bcea3 316 Pfam PF01758 Sodium Bile acid symporter family 42 218 1.3E-11 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AFA_RS14615 25f6481320a7b5256f21fee73efe1c66 224 TIGRFAM TIGR02796 tolQ: protein TolQ 8 221 3.3E-82 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 AFA_RS14615 25f6481320a7b5256f21fee73efe1c66 224 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 209 5.1E-41 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 546 1.3E-153 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 SUPERFAMILY SSF52540 1 215 1.23E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 503 2.2E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 Gene3D G3DSA:3.40.50.300 240 527 1.2E-20 T 28-03-2018 AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 Gene3D G3DSA:3.40.50.300 1 239 5.1E-26 T 28-03-2018 AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 SUPERFAMILY SSF52540 310 500 1.65E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 SUPERFAMILY SSF52540 3 50 1.65E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS13775 2a43244d6a0d9d021bcf46bd528f7fbd 548 PIRSF PIRSF003128 1 548 8.8E-161 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFA_RS15905 5e95b41731599d11f3515b915fb0889b 133 Pfam PF07681 DoxX 13 89 1.5E-7 T 28-03-2018 IPR032808 DoxX family AFA_RS16025 e747b4ad67d9f16df65f5be4cfa2ee48 300 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 8.9E-101 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 AFA_RS16025 e747b4ad67d9f16df65f5be4cfa2ee48 300 SUPERFAMILY SSF51735 1 297 2.37E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16025 e747b4ad67d9f16df65f5be4cfa2ee48 300 Gene3D G3DSA:3.40.50.720 1 300 3.3E-39 T 28-03-2018 AFA_RS16025 e747b4ad67d9f16df65f5be4cfa2ee48 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 1.9E-23 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS16025 e747b4ad67d9f16df65f5be4cfa2ee48 300 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 2.2E-20 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 AFA_RS08010 d129fe47f4cfe08515a609798d0a9e7d 313 Pfam PF02649 Type I GTP cyclohydrolase folE2 18 293 6.3E-66 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFA_RS08010 d129fe47f4cfe08515a609798d0a9e7d 313 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 5 298 32.386 T 28-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFA_RS08010 d129fe47f4cfe08515a609798d0a9e7d 313 Gene3D G3DSA:3.10.270.10 5 295 1.2E-76 T 28-03-2018 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 Gene3D G3DSA:3.20.20.70 16 361 4.0E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 7 364 1.0E-127 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 SUPERFAMILY SSF102114 104 328 6.02E-13 T 28-03-2018 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 Pfam PF04055 Radical SAM superfamily 110 288 1.4E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 6 361 71.94 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS11580 f4008303aaaad75a0a5c603c34051e7a 382 PIRSF PIRSF006004 5 373 6.5E-143 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 SUPERFAMILY SSF143800 1 78 6.67E-20 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 78 1.4E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 Pfam PF01197 Ribosomal protein L31 1 78 3.6E-27 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 PRINTS PR01249 Ribosomal protein L31 signature 44 59 1.0E-13 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 PRINTS PR01249 Ribosomal protein L31 signature 59 77 1.0E-13 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12785 f4fdd90de8666b5f598da0d8d00e9bd9 88 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-13 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS15260 4693b68a53763fa9e25ba7e6e5dda632 161 Gene3D G3DSA:3.90.960.10 2 152 6.4E-39 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS15260 4693b68a53763fa9e25ba7e6e5dda632 161 Pfam PF04073 Aminoacyl-tRNA editing domain 23 141 7.5E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS15260 4693b68a53763fa9e25ba7e6e5dda632 161 SUPERFAMILY SSF55826 5 151 3.01E-40 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 PRINTS PR01415 Ankyrin repeat signature 180 194 7.8E-7 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 PRINTS PR01415 Ankyrin repeat signature 132 147 7.8E-7 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 Pfam PF12796 Ankyrin repeats (3 copies) 124 195 3.0E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SUPERFAMILY SSF48403 40 218 5.6E-39 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 Gene3D G3DSA:1.25.40.20 20 229 4.0E-45 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SMART SM00248 67 97 5.6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SMART SM00248 164 193 0.013 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SMART SM00248 197 226 1900.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SMART SM00248 101 130 2900.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS10050 5373f90ae6a7bf599e09900944365cf1 298 SMART SM00248 131 160 4.1E-6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 AFA_RS04445 794d709e044769069519181e5d6baa60 332 Gene3D G3DSA:3.20.20.30 10 328 3.2E-75 T 28-03-2018 AFA_RS04445 794d709e044769069519181e5d6baa60 332 SUPERFAMILY SSF51679 7 326 1.31E-89 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS04445 794d709e044769069519181e5d6baa60 332 Pfam PF00296 Luciferase-like monooxygenase 20 299 1.8E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS04445 794d709e044769069519181e5d6baa60 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 7 326 6.6E-134 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 AFA_RS17535 5894a4860e0d7be28a27e6edd6a62455 291 Gene3D G3DSA:1.10.287.70 9 79 6.1E-16 T 28-03-2018 AFA_RS17535 5894a4860e0d7be28a27e6edd6a62455 291 SUPERFAMILY SSF81452 12 290 7.85E-77 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17535 5894a4860e0d7be28a27e6edd6a62455 291 Gene3D G3DSA:1.20.120.80 80 291 2.9E-69 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS17535 5894a4860e0d7be28a27e6edd6a62455 291 Pfam PF00510 Cytochrome c oxidase subunit III 18 291 1.7E-57 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 6.8E-73 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 107 127 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 44 64 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 65 85 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 3 22 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 128 149 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 23 43 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PRINTS PR00601 Bacterioferritin signature 86 106 7.4E-65 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 Gene3D G3DSA:1.20.5.420 85 138 5.5E-21 T 28-03-2018 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 PIRSF PIRSF002560 1 157 4.1E-72 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 Gene3D G3DSA:1.20.1260.10 3 78 2.1E-17 T 28-03-2018 IPR012347 Ferritin-related AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 Pfam PF00210 Ferritin-like domain 8 144 1.9E-39 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFA_RS00820 7249deedd50927b0aee509b36a02ea67 159 SUPERFAMILY SSF47240 1 156 1.24E-52 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS04065 fa43d67197f126e45ff52f574297e70f 233 Pfam PF00005 ABC transporter 28 169 2.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04065 fa43d67197f126e45ff52f574297e70f 233 SUPERFAMILY SSF52540 18 223 3.79E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04065 fa43d67197f126e45ff52f574297e70f 233 SMART SM00382 27 218 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS04065 fa43d67197f126e45ff52f574297e70f 233 Gene3D G3DSA:3.40.50.300 4 233 6.9E-49 T 28-03-2018 AFA_RS06535 e741766c3fe4feedd43c134d81fdc14b 178 SUPERFAMILY SSF54427 20 177 9.87E-42 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS06535 e741766c3fe4feedd43c134d81fdc14b 178 Gene3D G3DSA:3.10.450.50 18 178 8.1E-26 T 28-03-2018 AFA_RS06535 e741766c3fe4feedd43c134d81fdc14b 178 Pfam PF00866 Ring hydroxylating beta subunit 33 165 2.7E-24 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 SUPERFAMILY SSF46785 13 84 7.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 Gene3D G3DSA:3.40.1410.10 84 243 1.2E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 16 242 4.3E-86 T 28-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 Pfam PF07702 UTRA domain 101 238 2.4E-27 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 1.5E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 Gene3D G3DSA:1.10.10.10 4 83 6.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 4.9E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 4.9E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 SMART SM00345 21 80 2.2E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 SMART SM00866 101 238 2.5E-27 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFA_RS17680 3a84a3b83c47b057fbec6574ed35c969 243 SUPERFAMILY SSF64288 69 240 3.93E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 TIGRFAM TIGR01228 hutU: urocanate hydratase 19 569 5.7E-287 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Gene3D G3DSA:3.40.1770.10 19 162 1.9E-29 T 28-03-2018 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Gene3D G3DSA:3.40.1770.10 205 570 3.4E-158 T 28-03-2018 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 PIRSF PIRSF001423 5 571 1.7E-292 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 ProSitePatterns PS01233 Urocanase signature. 457 472 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Pfam PF17391 Urocanase N-terminal domain 21 147 3.1E-61 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Pfam PF17392 Urocanase C-terminal domain 367 561 3.5E-94 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 SUPERFAMILY SSF111326 14 570 6.93E-257 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Hamap MF_00577 Urocanate hydratase [hutU]. 4 571 50.643 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS17675 188612fd35595204b480e3a7dfcba995 571 Pfam PF01175 Urocanase Rossmann-like domain 150 364 6.1E-83 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFA_RS16030 e182450d34f00f2031631c8af6b2e50d 409 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 3 408 6.6E-112 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 AFA_RS16030 e182450d34f00f2031631c8af6b2e50d 409 Pfam PF03616 Sodium/glutamate symporter 3 376 2.7E-113 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 AFA_RS16030 e182450d34f00f2031631c8af6b2e50d 409 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 3 408 23.091 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 AFA_RS14870 30b76b70bb99347eac5ba021f7a72c9a 172 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 147 1.9E-45 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14870 30b76b70bb99347eac5ba021f7a72c9a 172 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 25.728 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14870 30b76b70bb99347eac5ba021f7a72c9a 172 Gene3D G3DSA:3.40.50.960 4 149 5.8E-49 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14870 30b76b70bb99347eac5ba021f7a72c9a 172 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 144 2.0E-36 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS14870 30b76b70bb99347eac5ba021f7a72c9a 172 SUPERFAMILY SSF52121 7 151 3.53E-47 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFA_RS05195 cf6ba15d7060c0331c38f709ac230868 132 Gene3D G3DSA:3.30.70.60 1 100 9.3E-29 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFA_RS05195 cf6ba15d7060c0331c38f709ac230868 132 Pfam PF01250 Ribosomal protein S6 3 89 1.3E-25 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05195 cf6ba15d7060c0331c38f709ac230868 132 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 91 8.8E-31 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05195 cf6ba15d7060c0331c38f709ac230868 132 SUPERFAMILY SSF54995 1 103 1.28E-34 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS05195 cf6ba15d7060c0331c38f709ac230868 132 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.11 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 SUPERFAMILY SSF52540 358 517 4.99E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 SUPERFAMILY SSF52540 6 215 3.97E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 Pfam PF00005 ABC transporter 31 171 2.6E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 Pfam PF00005 ABC transporter 358 485 1.1E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 Gene3D G3DSA:3.40.50.300 1 276 7.3E-46 T 28-03-2018 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 Gene3D G3DSA:3.40.50.300 336 526 1.3E-31 T 28-03-2018 AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 SMART SM00382 364 531 4.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02860 3220b69f888f67a38f338d972a28642f 537 SMART SM00382 30 216 5.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03090 a771deda56545e68c98238ce66f9d253 167 Pfam PF01967 MoaC family 23 158 1.7E-50 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 AFA_RS03090 a771deda56545e68c98238ce66f9d253 167 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 12 160 5.2E-56 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 AFA_RS03090 a771deda56545e68c98238ce66f9d253 167 Gene3D G3DSA:3.30.70.640 10 166 5.9E-64 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 AFA_RS03090 a771deda56545e68c98238ce66f9d253 167 SUPERFAMILY SSF55040 19 163 1.44E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 AFA_RS03090 a771deda56545e68c98238ce66f9d253 167 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 10 166 32.792 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 Gene3D G3DSA:3.90.226.10 20 319 5.4E-67 T 28-03-2018 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 49.807 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 3.8E-46 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 SUPERFAMILY SSF52096 5 316 3.59E-102 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 1.7E-65 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS04560 f450cf968ac6ce555d17e582fc6869f1 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 317 5.0E-149 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 AFA_RS14260 8b188eb9806add922eaeb974fb4d3ee4 183 Pfam PF04612 Type II secretion system (T2SS), protein M 21 175 2.6E-19 T 28-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 AFA_RS14260 8b188eb9806add922eaeb974fb4d3ee4 183 Gene3D G3DSA:3.30.1360.100 101 178 2.5E-5 T 28-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 Gene3D G3DSA:1.10.10.10 3 92 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 64 2.1E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 Gene3D G3DSA:3.40.190.10 185 273 9.8E-15 T 28-03-2018 AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 SUPERFAMILY SSF53850 97 297 2.58E-29 T 28-03-2018 AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 SUPERFAMILY SSF46785 8 117 1.59E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 Pfam PF03466 LysR substrate binding domain 97 297 3.4E-33 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS04460 95ee8eb44d72bc085abe3a3d16862d4b 311 Gene3D G3DSA:3.40.190.10 94 184 9.0E-15 T 28-03-2018 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 SUPERFAMILY SSF56954 6 36 7.98E-108 T 28-03-2018 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 SUPERFAMILY SSF56954 64 469 7.98E-108 T 28-03-2018 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 Gene3D G3DSA:1.20.1600.10 24 473 8.5E-103 T 28-03-2018 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 Pfam PF02321 Outer membrane efflux protein 73 258 4.7E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 Pfam PF02321 Outer membrane efflux protein 283 465 3.1E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AFA_RS16055 421363ab79cd89764b44b4dedb10851f 502 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 467 5.1E-118 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 Pfam PF01165 Ribosomal protein S21 4 57 1.9E-20 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 3.6E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 3.6E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 3.6E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 3.6E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 59 7.4E-23 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.91 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 Gene3D G3DSA:1.20.5.1150 16 52 6.2E-17 T 28-03-2018 AFA_RS11505 3bd18cc4c5f1f8448087c6afbbbfded4 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 1.0E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS11110 3829e34eac4bcaf7047338616cc6b0d6 544 Pfam PF00361 Proton-conducting membrane transporter 137 438 2.3E-30 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 7 150 4.3E-33 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 109 118 1.1E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 100 108 1.1E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 10 24 1.1E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 17 30 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 SUPERFAMILY SSF81330 17 146 5.89E-32 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS17205 4d383357c7bf6bd2dc4521591df202c8 151 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 7 150 7.4E-41 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 AFA_RS03800 0d12142b506ef7bf2017f20949cf6e76 348 Gene3D G3DSA:3.90.1200.10 103 346 4.3E-31 T 28-03-2018 AFA_RS03800 0d12142b506ef7bf2017f20949cf6e76 348 Pfam PF01636 Phosphotransferase enzyme family 35 266 4.2E-33 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase AFA_RS03800 0d12142b506ef7bf2017f20949cf6e76 348 Gene3D G3DSA:3.30.200.20 9 102 5.0E-30 T 28-03-2018 AFA_RS03800 0d12142b506ef7bf2017f20949cf6e76 348 SUPERFAMILY SSF56112 13 327 5.39E-47 T 28-03-2018 IPR011009 Protein kinase-like domain AFA_RS11940 1357bf531766086f8f2602c0739e0eda 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 52 75 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFA_RS11940 1357bf531766086f8f2602c0739e0eda 309 Gene3D G3DSA:3.40.1190.20 4 309 3.9E-63 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS11940 1357bf531766086f8f2602c0739e0eda 309 SUPERFAMILY SSF53613 13 308 6.08E-59 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS11940 1357bf531766086f8f2602c0739e0eda 309 Pfam PF00294 pfkB family carbohydrate kinase 13 302 7.5E-47 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB AFA_RS11940 1357bf531766086f8f2602c0739e0eda 309 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 9 308 1.8E-125 T 28-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Gene3D G3DSA:3.60.20.10 357 563 3.7E-41 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Gene3D G3DSA:3.60.20.10 217 350 8.3E-16 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 SUPERFAMILY SSF56235 31 219 1.21E-197 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 SUPERFAMILY SSF56235 258 812 1.21E-197 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 PIRSF PIRSF001227 24 811 9.3E-113 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Gene3D G3DSA:1.10.1400.10 564 711 2.4E-17 T 28-03-2018 AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Gene3D G3DSA:1.10.439.10 26 182 5.7E-43 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Gene3D G3DSA:1.10.287.150 183 206 4.2E-22 T 28-03-2018 AFA_RS10560 27bc4575899dc3c5518d64c835394faf 816 Pfam PF01804 Penicillin amidase 31 801 4.4E-138 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 AFA_RS06015 ca3d558f56ce979e18c7ac4839110993 698 Pfam PF05787 Bacterial protein of unknown function (DUF839) 87 660 3.5E-145 T 28-03-2018 IPR008557 Protein of unknown function DUF839 AFA_RS06015 ca3d558f56ce979e18c7ac4839110993 698 Gene3D G3DSA:3.40.190.10 27 634 1.5E-5 T 28-03-2018 AFA_RS05240 4bb0277240e0015b7a1ade9fc18fe502 147 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 142 2.6E-29 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AFA_RS05240 4bb0277240e0015b7a1ade9fc18fe502 147 Gene3D G3DSA:3.40.1230.10 1 147 2.0E-33 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AFA_RS05240 4bb0277240e0015b7a1ade9fc18fe502 147 SUPERFAMILY SSF64076 2 143 7.06E-30 T 28-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Gene3D G3DSA:3.40.50.2000 610 779 7.8E-38 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 SUPERFAMILY SSF53756 28 397 3.9E-68 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Pfam PF13477 Glycosyl transferase 4-like 428 577 1.8E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 SUPERFAMILY SSF53756 441 793 2.04E-66 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Pfam PF00534 Glycosyl transferases group 1 606 772 9.8E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Pfam PF00534 Glycosyl transferases group 1 209 361 2.3E-24 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Gene3D G3DSA:3.40.50.2000 22 208 1.6E-18 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Gene3D G3DSA:3.40.50.2000 421 609 2.9E-22 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Gene3D G3DSA:3.40.50.2000 209 381 2.8E-41 T 28-03-2018 AFA_RS02740 d3cd4bec0a01c489fb6067e2d82013d4 797 Pfam PF13439 Glycosyltransferase Family 4 39 201 5.8E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS17265 d8cfb1d1b5801b10ac88e555b0b5eb85 756 Gene3D G3DSA:3.40.50.2000 549 741 1.6E-13 T 28-03-2018 AFA_RS17265 d8cfb1d1b5801b10ac88e555b0b5eb85 756 SUPERFAMILY SSF53756 369 733 5.76E-25 T 28-03-2018 AFA_RS17265 d8cfb1d1b5801b10ac88e555b0b5eb85 756 Pfam PF00534 Glycosyl transferases group 1 581 717 1.2E-8 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 SUPERFAMILY SSF52172 1 173 6.26E-37 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS11010 368a778518574e1e4cef681099cc7495 229 SMART SM00862 145 218 1.2E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 SMART SM00448 1 112 6.0E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 9.7E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 Gene3D G3DSA:3.40.50.2300 1 121 2.3E-35 T 28-03-2018 AFA_RS11010 368a778518574e1e4cef681099cc7495 229 Gene3D G3DSA:1.10.10.10 122 225 4.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02685 dd66f6ab11fe41c36371a1e85bce7e99 61 Gene3D G3DSA:3.30.429.10 1 57 1.1E-15 T 28-03-2018 AFA_RS02685 dd66f6ab11fe41c36371a1e85bce7e99 61 Pfam PF01361 Tautomerase enzyme 2 57 1.4E-10 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AFA_RS02685 dd66f6ab11fe41c36371a1e85bce7e99 61 SUPERFAMILY SSF55331 1 60 3.4E-17 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 Gene3D G3DSA:1.10.357.10 68 228 6.3E-33 T 28-03-2018 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 SUPERFAMILY SSF46689 23 98 7.18E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 Gene3D G3DSA:1.10.10.60 9 67 9.4E-18 T 28-03-2018 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 5.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 5.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 SUPERFAMILY SSF48498 105 226 2.45E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFA_RS18575 bde5dd01003cb0bee9f2c9ea8115fa39 235 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 74 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 SMART SM00347 51 152 7.4E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 3.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 3.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 142 162 3.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 3.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 Gene3D G3DSA:1.10.10.10 22 171 3.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 SUPERFAMILY SSF46785 29 166 7.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00260 16d216c970b7fd5eea34f9f8a54d79d2 171 Pfam PF01047 MarR family 58 116 1.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS14385 91aeb8e2b5619df53f43bee955feb430 228 Pfam PF03591 AzlC protein 10 153 8.0E-34 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease AFA_RS15625 c109be4294aa987b9728b99d400cace7 163 Pfam PF05433 Glycine zipper 2TM domain 71 111 1.6E-6 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 Pfam PF01196 Ribosomal protein L17 20 116 1.2E-35 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 SUPERFAMILY SSF64263 1 119 1.15E-51 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.195 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 4.9E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17965 792f75b3952f3024c830a0ecd8e2d7dc 128 Gene3D G3DSA:3.90.1030.10 1 117 1.3E-50 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS07175 6fd8804b647ce52bcd793110a9688040 114 Pfam PF04342 Putative member of DMT superfamily (DUF486) 7 109 1.8E-45 T 28-03-2018 IPR007437 Putative member of DMT superfamily AFA_RS07175 6fd8804b647ce52bcd793110a9688040 114 PIRSF PIRSF021239 1 112 9.6E-50 T 28-03-2018 IPR007437 Putative member of DMT superfamily AFA_RS07175 6fd8804b647ce52bcd793110a9688040 114 SUPERFAMILY SSF103481 13 112 5.23E-5 T 28-03-2018 AFA_RS01090 9d6e280bb210669264ea9776ecb0f6ec 261 Gene3D G3DSA:3.40.50.300 4 259 4.7E-52 T 28-03-2018 AFA_RS01090 9d6e280bb210669264ea9776ecb0f6ec 261 SMART SM00382 35 236 1.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS01090 9d6e280bb210669264ea9776ecb0f6ec 261 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 4.1E-9 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFA_RS01090 9d6e280bb210669264ea9776ecb0f6ec 261 SUPERFAMILY SSF52540 10 258 2.4E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS01090 9d6e280bb210669264ea9776ecb0f6ec 261 Pfam PF00005 ABC transporter 26 187 5.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 Gene3D G3DSA:3.40.190.10 199 303 1.3E-12 T 28-03-2018 AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 SUPERFAMILY SSF53850 49 295 1.63E-56 T 28-03-2018 AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 293 2.8E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 SMART SM00079 74 294 0.0049 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 SMART SM00062 74 295 3.1E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFA_RS01665 c5c204ceb653039df7dff47600f04497 329 Gene3D G3DSA:3.40.190.10 70 198 2.8E-28 T 28-03-2018 AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 PIRSF PIRSF039085 2 245 1.7E-110 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 SMART SM00382 30 217 2.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 Pfam PF00005 ABC transporter 21 169 2.8E-38 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 SUPERFAMILY SSF52540 5 239 1.82E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS15820 0382d5e623629f53a68a373d8e2fa36c 245 Gene3D G3DSA:3.40.50.300 1 244 8.8E-79 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 SUPERFAMILY SSF101967 227 369 6.41E-12 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 Pfam PF03895 YadA-like membrane anchor domain 409 469 2.8E-18 T 28-03-2018 IPR005594 YadA-like, C-terminal AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 Gene3D G3DSA:2.150.10.10 227 366 2.3E-20 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 Gene3D G3DSA:2.150.10.10 130 226 3.7E-4 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 SUPERFAMILY SSF54523 358 469 1.0E-22 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 Gene3D G3DSA:3.30.1300.30 367 469 2.9E-21 T 28-03-2018 AFA_RS18095 be63634644d5b2a7f886c729e68b104e 469 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 347 375 1.3E-7 T 28-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFA_RS15030 9194b9180f6d7a154d7f5dcddefab7d8 324 SUPERFAMILY SSF53850 115 285 4.56E-10 T 28-03-2018 AFA_RS15030 9194b9180f6d7a154d7f5dcddefab7d8 324 Gene3D G3DSA:3.40.190.10 11 292 3.5E-5 T 28-03-2018 AFA_RS15030 9194b9180f6d7a154d7f5dcddefab7d8 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.4E-65 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS15030 9194b9180f6d7a154d7f5dcddefab7d8 324 PIRSF PIRSF017082 1 324 2.5E-64 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR01959 SuhB family inositol monophosphatase signature 173 199 9.5E-15 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR01959 SuhB family inositol monophosphatase signature 24 46 9.5E-15 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR01959 SuhB family inositol monophosphatase signature 121 140 9.5E-15 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR01959 SuhB family inositol monophosphatase signature 215 227 9.5E-15 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 225 249 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 147 170 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 194 215 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 1.9E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 SUPERFAMILY SSF56655 6 278 1.44E-73 T 28-03-2018 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 Gene3D G3DSA:3.40.190.80 167 286 1.8E-32 T 28-03-2018 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 Gene3D G3DSA:3.30.540.10 5 166 1.6E-43 T 28-03-2018 AFA_RS03740 792bea616e0120a86dedca50012cb2dc 287 Pfam PF00459 Inositol monophosphatase family 11 271 1.5E-53 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 Gene3D G3DSA:3.40.309.10 268 455 2.0E-64 T 28-03-2018 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 Gene3D G3DSA:3.40.605.10 4 267 1.8E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 Pfam PF00171 Aldehyde dehydrogenase family 17 482 6.0E-166 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AFA_RS17810 e2990921a8254d7d61f1d843d059af71 486 SUPERFAMILY SSF53720 8 485 3.14E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 262 274 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 93 112 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 32 47 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 47 62 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 67 82 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 115 132 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 132 150 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 172 190 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 PRINTS PR01010 Flagellar P-ring protein signature 198 216 3.0E-82 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 Hamap MF_00416 Flagellar P-ring protein [flgI]. 12 376 37.915 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS05855 1070e311db6b70011ace04f21fd1a29a 376 Pfam PF02119 Flagellar P-ring protein 32 375 3.3E-136 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 AFA_RS03705 b95e343960b0a69388b776c3f88cd549 310 Gene3D G3DSA:2.70.70.10 41 296 3.9E-44 T 28-03-2018 AFA_RS03705 b95e343960b0a69388b776c3f88cd549 310 SUPERFAMILY SSF51261 161 293 1.15E-54 T 28-03-2018 IPR011055 Duplicated hybrid motif AFA_RS03705 b95e343960b0a69388b776c3f88cd549 310 Pfam PF01551 Peptidase family M23 196 289 1.5E-33 T 28-03-2018 IPR016047 Peptidase M23 AFA_RS06825 19c82fbabe1d9fabf1e2a0ca1abdbcdb 218 Gene3D G3DSA:1.10.8.200 7 68 2.3E-12 T 28-03-2018 AFA_RS09760 ad5a687a56c93253bdb7ff7f947f5f81 185 TIGRFAM TIGR00608 radc: DNA repair protein RadC 43 185 1.7E-40 T 28-03-2018 IPR001405 RadC protein AFA_RS09760 ad5a687a56c93253bdb7ff7f947f5f81 185 Gene3D G3DSA:3.40.140.10 57 185 3.8E-42 T 28-03-2018 AFA_RS09760 ad5a687a56c93253bdb7ff7f947f5f81 185 Pfam PF04002 RadC-like JAB domain 62 183 1.9E-42 T 28-03-2018 IPR025657 RadC-like JAB domain AFA_RS09760 ad5a687a56c93253bdb7ff7f947f5f81 185 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 131 136 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site AFA_RS09760 ad5a687a56c93253bdb7ff7f947f5f81 185 SUPERFAMILY SSF102712 80 168 3.66E-5 T 28-03-2018 AFA_RS09005 8c1bef55d8a5ba33721e0cc40660af5b 309 Pfam PF03781 Sulfatase-modifying factor enzyme 1 34 211 9.2E-27 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFA_RS09005 8c1bef55d8a5ba33721e0cc40660af5b 309 SUPERFAMILY SSF56436 32 240 2.26E-35 T 28-03-2018 IPR016187 C-type lectin fold AFA_RS09005 8c1bef55d8a5ba33721e0cc40660af5b 309 Gene3D G3DSA:3.90.1580.10 24 244 7.9E-30 T 28-03-2018 AFA_RS01915 f7bef2408a427dfb93d08bf0ec7eddbe 174 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 121 6.1E-13 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFA_RS01915 f7bef2408a427dfb93d08bf0ec7eddbe 174 SUPERFAMILY SSF69118 1 172 6.81E-42 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS01915 f7bef2408a427dfb93d08bf0ec7eddbe 174 Gene3D G3DSA:1.20.1290.10 41 174 1.7E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFA_RS01915 f7bef2408a427dfb93d08bf0ec7eddbe 174 Gene3D G3DSA:1.20.5.810 11 40 0.0034 T 28-03-2018 AFA_RS09545 5284196a7a9bf7cc76264246e9ff4e73 408 Gene3D G3DSA:2.130.10.10 1 391 2.9E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS00175 1d1fbda52f618e0dea7cf88ad503efe3 327 Gene3D G3DSA:3.40.190.10 170 300 4.5E-15 T 28-03-2018 AFA_RS00175 1d1fbda52f618e0dea7cf88ad503efe3 327 PIRSF PIRSF002825 9 325 6.4E-80 T 28-03-2018 IPR026045 Ferric binding protein AFA_RS00175 1d1fbda52f618e0dea7cf88ad503efe3 327 SUPERFAMILY SSF53850 22 321 4.23E-61 T 28-03-2018 AFA_RS00175 1d1fbda52f618e0dea7cf88ad503efe3 327 Gene3D G3DSA:3.40.190.10 25 169 4.5E-21 T 28-03-2018 AFA_RS00175 1d1fbda52f618e0dea7cf88ad503efe3 327 Pfam PF13343 Bacterial extracellular solute-binding protein 75 296 8.6E-30 T 28-03-2018 AFA_RS15635 29c994f732971c40994ec304cac91fe9 422 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 39 1.1E-5 T 28-03-2018 IPR011723 Zinc finger/thioredoxin putative AFA_RS15635 29c994f732971c40994ec304cac91fe9 422 Pfam PF11906 Protein of unknown function (DUF3426) 274 417 3.6E-40 T 28-03-2018 IPR021834 Protein of unknown function DUF3426 AFA_RS13370 bcabe8b3cec029edc18da2b44ba8d115 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 8.1E-23 T 28-03-2018 AFA_RS13370 bcabe8b3cec029edc18da2b44ba8d115 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 20.233 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 SMART SM00893 23 211 1.7E-68 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 Gene3D G3DSA:3.40.50.620 1 248 1.9E-88 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 Pfam PF01012 Electron transfer flavoprotein domain 28 206 6.2E-47 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 PIRSF PIRSF000090 1 249 2.6E-87 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFA_RS11910 0c07a915f914dc5e965a1ba7b9cb3004 249 SUPERFAMILY SSF52402 1 242 1.05E-86 T 28-03-2018 AFA_RS12830 79335dee147b809059c2618dd8b940cb 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 6.2E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS12830 79335dee147b809059c2618dd8b940cb 55 Pfam PF00471 Ribosomal protein L33 7 53 3.8E-18 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS12830 79335dee147b809059c2618dd8b940cb 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS12830 79335dee147b809059c2618dd8b940cb 55 SUPERFAMILY SSF57829 1 53 1.1E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFA_RS12830 79335dee147b809059c2618dd8b940cb 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.811 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS00710 a330fd5dc8fc91bb9a2a7d9904986d16 213 Gene3D G3DSA:3.40.30.10 26 210 1.4E-36 T 28-03-2018 AFA_RS00710 a330fd5dc8fc91bb9a2a7d9904986d16 213 Pfam PF01323 DSBA-like thioredoxin domain 88 187 5.1E-12 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 AFA_RS00710 a330fd5dc8fc91bb9a2a7d9904986d16 213 SUPERFAMILY SSF52833 48 190 9.1E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS00710 a330fd5dc8fc91bb9a2a7d9904986d16 213 PIRSF PIRSF001488 11 213 2.5E-50 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL AFA_RS09290 b0c0aed47ab191e435569869998c3d84 203 SUPERFAMILY SSF52972 5 200 9.16E-66 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS09290 b0c0aed47ab191e435569869998c3d84 203 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 6 202 44.901 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 AFA_RS09290 b0c0aed47ab191e435569869998c3d84 203 Pfam PF01725 Ham1 family 8 198 6.0E-53 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 AFA_RS09290 b0c0aed47ab191e435569869998c3d84 203 Gene3D G3DSA:3.90.950.10 1 203 2.8E-72 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS09290 b0c0aed47ab191e435569869998c3d84 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 8 198 5.8E-49 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 AFA_RS04355 b8742dcea3303152b9e97894e0c3c18b 138 Pfam PF16220 Domain of unknown function (DUF4880) 22 62 2.0E-7 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS04610 6f5be91250baf95597483cd0b9ab4bd3 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 42 1.1E-5 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS04610 6f5be91250baf95597483cd0b9ab4bd3 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 123 2.8E-8 T 28-03-2018 IPR001451 Hexapeptide repeat AFA_RS04610 6f5be91250baf95597483cd0b9ab4bd3 196 Gene3D G3DSA:2.160.10.10 1 176 2.9E-38 T 28-03-2018 AFA_RS04610 6f5be91250baf95597483cd0b9ab4bd3 196 SUPERFAMILY SSF51161 4 166 9.7E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like AFA_RS13240 9911c20d254a42c93c1b0ab8c39c66f2 260 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS13240 9911c20d254a42c93c1b0ab8c39c66f2 260 Pfam PF00005 ABC transporter 28 176 2.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS13240 9911c20d254a42c93c1b0ab8c39c66f2 260 Gene3D G3DSA:3.40.50.300 5 249 4.5E-50 T 28-03-2018 AFA_RS13240 9911c20d254a42c93c1b0ab8c39c66f2 260 SMART SM00382 35 221 8.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS13240 9911c20d254a42c93c1b0ab8c39c66f2 260 SUPERFAMILY SSF52540 9 246 4.35E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17360 d6651e46f79d362ab813a1d763b1c1c1 471 Gene3D G3DSA:1.20.1250.20 265 461 1.2E-12 T 28-03-2018 AFA_RS17360 d6651e46f79d362ab813a1d763b1c1c1 471 SUPERFAMILY SSF103473 250 460 2.88E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17360 d6651e46f79d362ab813a1d763b1c1c1 471 SUPERFAMILY SSF103473 13 202 2.88E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17360 d6651e46f79d362ab813a1d763b1c1c1 471 Pfam PF07690 Major Facilitator Superfamily 26 418 1.3E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS17360 d6651e46f79d362ab813a1d763b1c1c1 471 Gene3D G3DSA:1.20.1250.20 18 207 4.2E-25 T 28-03-2018 AFA_RS09455 9122b9701dab42c48f41f71d9bfce1bd 385 Pfam PF07995 Glucose / Sorbosone dehydrogenase 45 380 4.6E-128 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFA_RS09455 9122b9701dab42c48f41f71d9bfce1bd 385 SUPERFAMILY SSF50952 20 382 2.22E-48 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFA_RS09455 9122b9701dab42c48f41f71d9bfce1bd 385 Gene3D G3DSA:2.120.10.30 21 284 2.0E-53 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFA_RS09455 9122b9701dab42c48f41f71d9bfce1bd 385 Gene3D G3DSA:2.120.10.30 285 378 2.7E-16 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFA_RS18550 2f6d65c56411369133101dab891883c3 275 Gene3D G3DSA:3.40.50.1820 14 269 1.3E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS18550 2f6d65c56411369133101dab891883c3 275 Pfam PF12697 Alpha/beta hydrolase family 36 263 7.6E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS18550 2f6d65c56411369133101dab891883c3 275 SUPERFAMILY SSF53474 16 271 6.54E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS10230 d24f17c229c0b126404946bbcc906784 166 Gene3D G3DSA:1.20.1550.10 1 165 7.3E-26 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain AFA_RS10230 d24f17c229c0b126404946bbcc906784 166 SUPERFAMILY SSF158442 12 159 6.02E-22 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain AFA_RS10230 d24f17c229c0b126404946bbcc906784 166 Pfam PF02600 Disulfide bond formation protein DsbB 11 157 2.0E-27 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 AFA_RS09200 72f20e01e2df8cdfd22ea285ea633748 95 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 1.5E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS09200 72f20e01e2df8cdfd22ea285ea633748 95 Pfam PF09723 Zinc ribbon domain 1 35 4.9E-9 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS09200 72f20e01e2df8cdfd22ea285ea633748 95 SMART SM00834 1 43 1.6E-6 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFA_RS00655 e8c54c09f030859f8ec36e6158dc416d 575 Pfam PF14351 Domain of unknown function (DUF4401) 61 376 7.2E-16 T 28-03-2018 IPR025513 Domain of unknown function DUF4401 AFA_RS00655 e8c54c09f030859f8ec36e6158dc416d 575 Pfam PF14345 GDYXXLXY protein 407 566 1.3E-31 T 28-03-2018 IPR025833 GDYXXLXY protein AFA_RS14735 9f7c1f52b06f153682d463de1e6f039a 245 SUPERFAMILY SSF52402 18 198 1.13E-38 T 28-03-2018 AFA_RS14735 9f7c1f52b06f153682d463de1e6f039a 245 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 41 234 3.5E-76 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 AFA_RS14735 9f7c1f52b06f153682d463de1e6f039a 245 Gene3D G3DSA:3.40.50.620 3 245 2.5E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS14735 9f7c1f52b06f153682d463de1e6f039a 245 PIRSF PIRSF000857 17 241 3.5E-76 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFA_RS14735 9f7c1f52b06f153682d463de1e6f039a 245 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 37 210 5.0E-37 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 AFA_RS17390 8d7fc37e09ee504508cdc012c1a4015b 281 Gene3D G3DSA:3.40.710.10 11 279 1.1E-33 T 28-03-2018 AFA_RS17390 8d7fc37e09ee504508cdc012c1a4015b 281 Pfam PF13354 Beta-lactamase enzyme family 44 245 2.9E-57 T 28-03-2018 AFA_RS17390 8d7fc37e09ee504508cdc012c1a4015b 281 SUPERFAMILY SSF56601 17 253 3.22E-48 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS13410 61e3e838af60419778f65bef6997e384 203 SUPERFAMILY SSF143243 21 185 3.01E-52 T 28-03-2018 AFA_RS13410 61e3e838af60419778f65bef6997e384 203 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 163 1.2E-39 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13410 61e3e838af60419778f65bef6997e384 203 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 125 146 - T 28-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13410 61e3e838af60419778f65bef6997e384 203 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 11 172 34.098 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13410 61e3e838af60419778f65bef6997e384 203 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 165 3.7E-43 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13410 61e3e838af60419778f65bef6997e384 203 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 91 152 3.0E-21 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 SUPERFAMILY SSF46785 16 154 5.64E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 Gene3D G3DSA:1.10.10.10 4 154 5.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 Pfam PF01047 MarR family 45 103 3.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 5.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 5.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 5.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS08340 0d3633e6861fb8d40101d0e42ee9c0de 159 SMART SM00347 38 138 1.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS03610 8e7ad8c051700b6b730805b087c00afc 102 SUPERFAMILY SSF54292 7 81 2.62E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS03610 8e7ad8c051700b6b730805b087c00afc 102 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 34 42 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFA_RS03610 8e7ad8c051700b6b730805b087c00afc 102 Gene3D G3DSA:3.10.20.30 2 95 6.8E-14 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS03610 8e7ad8c051700b6b730805b087c00afc 102 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 73 3.7E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 65 462 3.1E-57 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 SUPERFAMILY SSF56601 34 479 4.2E-87 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 39 479 5.9E-80 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 Gene3D G3DSA:3.40.710.10 31 481 1.3E-35 T 28-03-2018 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 439 452 3.2E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 74 93 3.2E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 362 376 3.2E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 377 391 3.2E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS03260 b931f7f7bb6513aaaddf6f39de9fc7e9 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 304 326 3.2E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFA_RS14155 e7d482172476b89f7343848a5cf59d4c 196 SUPERFAMILY SSF46626 70 176 5.01E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14155 e7d482172476b89f7343848a5cf59d4c 196 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 69 153 7.4E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS14155 e7d482172476b89f7343848a5cf59d4c 196 PRINTS PR00605 Class IC cytochrome C signature 131 153 2.4E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS14155 e7d482172476b89f7343848a5cf59d4c 196 PRINTS PR00605 Class IC cytochrome C signature 78 89 2.4E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AFA_RS14155 e7d482172476b89f7343848a5cf59d4c 196 Gene3D G3DSA:1.10.760.10 53 184 9.8E-27 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS04775 3fb235c39feb71d23e4e9899f0c6484f 405 Pfam PF11062 Protein of unknown function (DUF2863) 14 401 1.6E-129 T 28-03-2018 IPR021292 Protein of unknown function DUF2863 AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 SUPERFAMILY SSF47973 2 149 1.19E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.4E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.079 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 Gene3D G3DSA:1.10.455.10 6 156 2.1E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 PIRSF PIRSF002122 3 156 1.9E-57 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AFA_RS18300 d6a223f7b8da53bda668b81037b235d0 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.3E-65 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFA_RS17595 058dc03f4e8db4360cb4c799cabe5678 297 Pfam PF00756 Putative esterase 58 291 9.4E-52 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFA_RS17595 058dc03f4e8db4360cb4c799cabe5678 297 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 6 297 1.1E-130 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 AFA_RS17595 058dc03f4e8db4360cb4c799cabe5678 297 Gene3D G3DSA:3.40.50.1820 1 297 3.1E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS17595 058dc03f4e8db4360cb4c799cabe5678 297 SUPERFAMILY SSF53474 5 297 2.57E-83 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01105 8f7e425485d74970d9beb1d719c16241 439 Pfam PF13458 Periplasmic binding protein 31 399 3.2E-76 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS01105 8f7e425485d74970d9beb1d719c16241 439 Gene3D G3DSA:3.40.50.2300 15 159 2.8E-7 T 28-03-2018 AFA_RS01105 8f7e425485d74970d9beb1d719c16241 439 Gene3D G3DSA:3.40.50.2300 160 340 4.0E-22 T 28-03-2018 AFA_RS01105 8f7e425485d74970d9beb1d719c16241 439 SUPERFAMILY SSF53822 32 405 4.71E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 Pfam PF02545 Maf-like protein 2 183 3.8E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 PIRSF PIRSF006305 1 190 4.7E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 2.8E-39 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 Gene3D G3DSA:3.90.950.10 1 188 2.5E-50 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 Hamap MF_00528 Septum formation protein Maf [maf]. 2 188 26.803 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 AFA_RS13140 e1a1cb1462b7d94f619ce87647f0131c 198 SUPERFAMILY SSF52972 1 183 2.09E-50 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFA_RS09965 9bd7151d57c9f8d9314854755b4ba733 167 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 5 160 3.5E-51 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 AFA_RS09965 9bd7151d57c9f8d9314854755b4ba733 167 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 6 159 5.8E-53 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 AFA_RS09965 9bd7151d57c9f8d9314854755b4ba733 167 PIRSF PIRSF028301 1 167 5.0E-55 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 Pfam PF00593 TonB dependent receptor 377 1059 1.5E-24 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 Pfam PF07715 TonB-dependent Receptor Plug Domain 86 183 1.5E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 Gene3D G3DSA:2.40.170.20 193 1061 4.2E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 Gene3D G3DSA:2.170.130.10 48 192 2.0E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 77 210 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 776 916 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 263 306 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 498 601 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 338 445 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 SUPERFAMILY SSF56935 947 1061 3.05E-66 T 28-03-2018 AFA_RS08140 40d3398f2043158a327a92cdc71058b0 1061 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 1044 1061 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS05390 35c75c55e5fdb79576c0752d66ff91dc 394 Pfam PF13439 Glycosyltransferase Family 4 30 188 7.3E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS05390 35c75c55e5fdb79576c0752d66ff91dc 394 Pfam PF00534 Glycosyl transferases group 1 200 367 2.7E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS05390 35c75c55e5fdb79576c0752d66ff91dc 394 SUPERFAMILY SSF53756 18 388 1.75E-67 T 28-03-2018 AFA_RS05390 35c75c55e5fdb79576c0752d66ff91dc 394 Gene3D G3DSA:3.40.50.2000 174 384 1.8E-38 T 28-03-2018 AFA_RS08560 670e9d782f65b325922f09a5a65024b7 162 Pfam PF00866 Ring hydroxylating beta subunit 14 154 5.2E-47 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 AFA_RS08560 670e9d782f65b325922f09a5a65024b7 162 TIGRFAM TIGR03232 benzo_1_2_benB: benzoate 1,2-dioxygenase, small subunit 8 162 9.6E-75 T 28-03-2018 IPR017641 Benzoate 1,2-dioxygenase, small subunit GO:0016708|GO:0055114 AFA_RS08560 670e9d782f65b325922f09a5a65024b7 162 Gene3D G3DSA:3.10.450.50 2 162 2.5E-32 T 28-03-2018 AFA_RS08560 670e9d782f65b325922f09a5a65024b7 162 SUPERFAMILY SSF54427 3 162 1.02E-53 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS12405 c1e672c89722b56d00847754cf5f1018 278 Pfam PF01380 SIS domain 129 217 3.5E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFA_RS12405 c1e672c89722b56d00847754cf5f1018 278 SUPERFAMILY SSF53697 101 261 6.3E-7 T 28-03-2018 AFA_RS12405 c1e672c89722b56d00847754cf5f1018 278 Gene3D G3DSA:1.10.10.10 3 82 4.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12405 c1e672c89722b56d00847754cf5f1018 278 SUPERFAMILY SSF46689 7 82 3.58E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS12405 c1e672c89722b56d00847754cf5f1018 278 Gene3D G3DSA:3.40.50.10490 94 277 8.7E-10 T 28-03-2018 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 TIGRFAM TIGR00526 folB_dom: FolB domain 5 119 1.5E-19 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 SUPERFAMILY SSF55620 3 119 2.95E-28 T 28-03-2018 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 Gene3D G3DSA:3.30.1130.10 3 119 2.5E-28 T 28-03-2018 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 SMART SM00905 6 117 8.0E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 117 3.2E-23 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFA_RS16650 bb222eba402cb66eeb7f0260f990e7e2 119 Pfam PF02152 Dihydroneopterin aldolase 6 116 8.4E-27 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFA_RS16800 4cc7622609b535152ff812c45010f3eb 259 SUPERFAMILY SSF161098 56 240 4.97E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16800 4cc7622609b535152ff812c45010f3eb 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 248 3.7E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS16800 4cc7622609b535152ff812c45010f3eb 259 Gene3D G3DSA:1.10.3720.10 12 256 3.6E-24 T 28-03-2018 AFA_RS13015 c33d2409c8c8fe3600942a9976a0b41a 368 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 356 3.1E-103 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 AFA_RS13015 c33d2409c8c8fe3600942a9976a0b41a 368 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 356 7.7E-59 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 PIRSF PIRSF004669 1 89 4.6E-31 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.5E-20 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.5E-20 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.5E-20 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 Pfam PF01313 Bacterial export proteins, family 3 6 78 9.5E-29 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFA_RS05905 ab3428db684717c234fd774346d3444d 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 85 3.3E-30 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 536 552 - T 28-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 Gene3D G3DSA:3.30.70.1450 211 293 1.1E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 SUPERFAMILY SSF116726 211 290 2.35E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 SUPERFAMILY SSF116726 299 380 7.98E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 Gene3D G3DSA:3.30.70.1450 295 379 5.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 Pfam PF03600 Citrate transporter 16 534 1.9E-49 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 Pfam PF02080 TrkA-C domain 308 376 5.8E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS07595 2e8fd6611b08a1fad9ff41255dcdf5d8 591 Pfam PF02080 TrkA-C domain 218 286 1.0E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFA_RS04020 a70633e7fec1f5e74f68df97334f114c 141 Pfam PF05232 Chlorhexidine efflux transporter 5 67 3.3E-18 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter AFA_RS04020 a70633e7fec1f5e74f68df97334f114c 141 Pfam PF05232 Chlorhexidine efflux transporter 73 135 6.1E-20 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter AFA_RS03225 cb4dbf05e3d570881cf167fba26617c0 73 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 59 3.6E-25 T 28-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system AFA_RS03225 cb4dbf05e3d570881cf167fba26617c0 73 Gene3D G3DSA:1.10.1220.10 4 37 6.6E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS13635 f033fa3be7709c818f044296c0fe3674 212 Gene3D G3DSA:1.20.1170.10 13 211 5.1E-5 T 28-03-2018 AFA_RS13635 f033fa3be7709c818f044296c0fe3674 212 Pfam PF11180 Protein of unknown function (DUF2968) 31 202 2.0E-54 T 28-03-2018 IPR021350 Protein of unknown function DUF2968 AFA_RS01150 3c004e7db8911e6e88522fc2653c9013 311 SUPERFAMILY SSF103481 204 303 1.31E-15 T 28-03-2018 AFA_RS01150 3c004e7db8911e6e88522fc2653c9013 311 SUPERFAMILY SSF103481 60 157 6.93E-13 T 28-03-2018 AFA_RS01150 3c004e7db8911e6e88522fc2653c9013 311 Pfam PF00892 EamA-like transporter family 23 154 1.5E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS01150 3c004e7db8911e6e88522fc2653c9013 311 Pfam PF00892 EamA-like transporter family 163 297 1.8E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS10340 d7e71f9574cf80a2eedddea0f71b239e 177 Gene3D G3DSA:3.40.50.9100 13 168 7.3E-36 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS10340 d7e71f9574cf80a2eedddea0f71b239e 177 Pfam PF01220 Dehydroquinase class II 18 161 9.2E-32 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS10340 d7e71f9574cf80a2eedddea0f71b239e 177 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 119 8.0E-18 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS10340 d7e71f9574cf80a2eedddea0f71b239e 177 PIRSF PIRSF001399 14 168 3.0E-28 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS10340 d7e71f9574cf80a2eedddea0f71b239e 177 SUPERFAMILY SSF52304 18 168 4.06E-30 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFA_RS06155 fa17fab993c3420c90505941935ee525 385 SUPERFAMILY SSF56796 5 384 6.41E-117 T 28-03-2018 AFA_RS06155 fa17fab993c3420c90505941935ee525 385 Gene3D G3DSA:1.20.1090.10 182 385 3.7E-60 T 28-03-2018 AFA_RS06155 fa17fab993c3420c90505941935ee525 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 376 5.0E-115 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFA_RS06155 fa17fab993c3420c90505941935ee525 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFA_RS06155 fa17fab993c3420c90505941935ee525 385 Gene3D G3DSA:3.40.50.1970 7 181 1.1E-46 T 28-03-2018 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 SUPERFAMILY SSF46785 9 90 3.88E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 3.1E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 Gene3D G3DSA:1.10.10.10 8 92 9.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 Pfam PF03466 LysR substrate binding domain 101 303 8.4E-9 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 SUPERFAMILY SSF53850 96 303 8.14E-23 T 28-03-2018 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 Gene3D G3DSA:3.40.190.10 96 309 4.9E-8 T 28-03-2018 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS16765 ff17f215547eb4f4ccf37e21d2d296e7 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS05610 64003b1cb0b85883e06e7fc91565fc17 507 Pfam PF02690 Na+/Pi-cotransporter 1 135 3.6E-35 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 AFA_RS05610 64003b1cb0b85883e06e7fc91565fc17 507 Pfam PF02690 Na+/Pi-cotransporter 130 235 4.7E-13 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 SUPERFAMILY SSF53613 1 292 2.96E-51 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 Pfam PF00294 pfkB family carbohydrate kinase 1 288 2.4E-39 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 Gene3D G3DSA:3.40.1190.20 1 299 2.9E-49 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 PRINTS PR00990 Ribokinase signature 29 48 1.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 PRINTS PR00990 Ribokinase signature 1 21 1.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 PRINTS PR00990 Ribokinase signature 101 114 1.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 PRINTS PR00990 Ribokinase signature 220 231 1.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFA_RS08655 7deb57fbbf7dec03b4c427449fb3864b 308 PRINTS PR00990 Ribokinase signature 170 185 1.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFA_RS03545 9ee6e66a8a4c1fac0d54d71eaf3250fb 75 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 8 33 2.0E-4 T 28-03-2018 AFA_RS03545 9ee6e66a8a4c1fac0d54d71eaf3250fb 75 Pfam PF05433 Glycine zipper 2TM domain 34 72 3.4E-6 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 AFA_RS09600 dc3ababb2de9cfc276781bcbc31c1146 386 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 130 384 5.4E-63 T 28-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 AFA_RS09600 dc3ababb2de9cfc276781bcbc31c1146 386 Pfam PF11920 Protein of unknown function (DUF3438) 132 380 2.4E-43 T 28-03-2018 IPR021844 Integrating conjugative element protein, PFL4704 AFA_RS00215 07a017787b0c04322fdc8f61ca2aa663 387 SUPERFAMILY SSF103473 3 377 2.22E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS00215 07a017787b0c04322fdc8f61ca2aa663 387 Pfam PF07690 Major Facilitator Superfamily 2 339 2.2E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS00215 07a017787b0c04322fdc8f61ca2aa663 387 Gene3D G3DSA:1.20.1250.20 1 184 3.2E-16 T 28-03-2018 AFA_RS00215 07a017787b0c04322fdc8f61ca2aa663 387 Gene3D G3DSA:1.20.1250.20 196 386 1.5E-15 T 28-03-2018 AFA_RS06385 3e4161ac031eb0b8a564c02a3a1e83a1 216 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 7 147 1.2E-31 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AFA_RS06385 3e4161ac031eb0b8a564c02a3a1e83a1 216 Gene3D G3DSA:1.10.760.10 28 196 1.5E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06385 3e4161ac031eb0b8a564c02a3a1e83a1 216 SUPERFAMILY SSF46626 90 185 3.51E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06385 3e4161ac031eb0b8a564c02a3a1e83a1 216 SUPERFAMILY SSF46626 3 63 3.51E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS04005 198602e937d4376612bbd0cc484e70b4 173 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 160 8.9E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 Pfam PF04055 Radical SAM superfamily 31 198 1.4E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 Pfam PF06463 Molybdenum Cofactor Synthesis C 208 333 7.8E-37 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 SMART SM00729 26 239 3.4E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 32 43 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 19 353 2.0E-114 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 Pfam PF13353 4Fe-4S single cluster domain 33 132 1.0E-8 T 28-03-2018 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 Gene3D G3DSA:3.20.20.70 13 353 1.5E-77 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 17 353 40.74 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 AFA_RS03060 d70db16ffef6491ec0c8bb54ea134b18 353 SUPERFAMILY SSF102114 19 299 4.97E-75 T 28-03-2018 AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 Pfam PF00263 Bacterial type II and III secretion system protein 548 714 1.1E-52 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 PRINTS PR00811 Bacterial general secretion pathway protein D signature 701 715 1.3E-31 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 PRINTS PR00811 Bacterial general secretion pathway protein D signature 461 471 1.3E-31 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 PRINTS PR00811 Bacterial general secretion pathway protein D signature 678 696 1.3E-31 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 PRINTS PR00811 Bacterial general secretion pathway protein D signature 579 589 1.3E-31 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 PRINTS PR00811 Bacterial general secretion pathway protein D signature 544 568 1.3E-31 T 28-03-2018 IPR001775 GspD/PilQ family AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 Pfam PF03958 Bacterial type II/III secretion system short domain 264 331 1.9E-12 T 28-03-2018 IPR005644 NolW-like AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 Pfam PF03958 Bacterial type II/III secretion system short domain 200 259 3.3E-11 T 28-03-2018 IPR005644 NolW-like AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 Pfam PF03958 Bacterial type II/III secretion system short domain 337 461 1.7E-15 T 28-03-2018 IPR005644 NolW-like AFA_RS14250 3df8aaaa595429dbe62c0f5fb790cf8b 769 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 103 723 4.5E-193 T 28-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 AFA_RS10845 d431f5cfa401d6a66e7240495bc1e212 136 Pfam PF09842 Predicted membrane protein (DUF2069) 13 111 4.3E-30 T 28-03-2018 IPR018643 Protein of unknown function DUF2069, membrane AFA_RS11820 8f5e731738cda2c067f15566e53c0573 153 SUPERFAMILY SSF54637 11 137 9.06E-29 T 28-03-2018 IPR029069 HotDog domain AFA_RS11820 8f5e731738cda2c067f15566e53c0573 153 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 30 140 5.1E-25 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFA_RS11820 8f5e731738cda2c067f15566e53c0573 153 Gene3D G3DSA:3.10.129.10 2 145 1.1E-30 T 28-03-2018 AFA_RS11820 8f5e731738cda2c067f15566e53c0573 153 Pfam PF03061 Thioesterase superfamily 59 132 4.6E-13 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS11820 8f5e731738cda2c067f15566e53c0573 153 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 30 142 4.1E-49 T 28-03-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.2E-33 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 Gene3D G3DSA:3.40.50.2300 218 354 1.7E-14 T 28-03-2018 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 Gene3D G3DSA:3.40.50.2300 26 217 1.9E-40 T 28-03-2018 AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 SUPERFAMILY SSF53822 27 371 4.42E-85 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS09395 0e561d6291d02ccb7897b508318758e2 373 Pfam PF13458 Periplasmic binding protein 28 365 8.0E-52 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS13910 a274ce8ac30ec56bccd6aca67d8783bc 182 Gene3D G3DSA:3.10.450.50 3 182 9.9E-36 T 28-03-2018 AFA_RS13910 a274ce8ac30ec56bccd6aca67d8783bc 182 SUPERFAMILY SSF54427 14 181 8.22E-44 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS13910 a274ce8ac30ec56bccd6aca67d8783bc 182 Pfam PF00866 Ring hydroxylating beta subunit 29 174 4.7E-47 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 AFA_RS11635 fa0c35353d922e9aab28d9cf00ee4573 117 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 28-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFA_RS11635 fa0c35353d922e9aab28d9cf00ee4573 117 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 117 1.4E-39 T 28-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 AFA_RS11635 fa0c35353d922e9aab28d9cf00ee4573 117 SUPERFAMILY SSF49472 1 117 1.19E-40 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFA_RS11635 fa0c35353d922e9aab28d9cf00ee4573 117 Gene3D G3DSA:2.60.40.180 1 117 8.2E-38 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFA_RS11635 fa0c35353d922e9aab28d9cf00ee4573 117 Pfam PF00576 HIUase/Transthyretin family 4 116 1.0E-34 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 AFA_RS03835 1bf6b83e7e83fe8098fb70b7dce464d2 249 Gene3D G3DSA:3.40.1130.10 27 237 3.9E-40 T 28-03-2018 AFA_RS03835 1bf6b83e7e83fe8098fb70b7dce464d2 249 SMART SM00563 71 186 1.7E-31 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AFA_RS03835 1bf6b83e7e83fe8098fb70b7dce464d2 249 Pfam PF01553 Acyltransferase 61 183 1.4E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AFA_RS03835 1bf6b83e7e83fe8098fb70b7dce464d2 249 SUPERFAMILY SSF69593 6 240 7.32E-42 T 28-03-2018 AFA_RS03400 bcba013cef7d3b2512ee05a9f2547133 129 SUPERFAMILY SSF47598 90 124 6.04E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFA_RS03400 bcba013cef7d3b2512ee05a9f2547133 129 Gene3D G3DSA:3.30.2390.10 2 70 1.2E-11 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like AFA_RS03400 bcba013cef7d3b2512ee05a9f2547133 129 SUPERFAMILY SSF143100 1 61 1.15E-12 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like AFA_RS03400 bcba013cef7d3b2512ee05a9f2547133 129 Gene3D G3DSA:1.10.1220.10 86 128 2.3E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS03400 bcba013cef7d3b2512ee05a9f2547133 129 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 122 4.7E-39 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 820 942 7.6E-31 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 Pfam PF13244 Domain of unknown function (DUF4040) 613 678 2.8E-17 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 113 3.2E-8 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 Pfam PF00361 Proton-conducting membrane transporter 126 404 9.9E-65 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 3.1E-40 T 28-03-2018 AFA_RS11100 9c6d9a03be6b1b901651d89155231117 975 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 3.1E-40 T 28-03-2018 AFA_RS17620 445e1bbb5457c975610f24447a4f121d 216 Pfam PF04367 Protein of unknown function (DUF502) 56 161 2.8E-35 T 28-03-2018 IPR007462 Protein of unknown function DUF502 AFA_RS03505 418e0f7039c96b125551d0a279d305a3 266 Pfam PF00899 ThiF family 23 164 8.7E-28 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS03505 418e0f7039c96b125551d0a279d305a3 266 Gene3D G3DSA:3.40.50.720 2 266 9.9E-45 T 28-03-2018 AFA_RS03505 418e0f7039c96b125551d0a279d305a3 266 SUPERFAMILY SSF69572 6 266 1.31E-51 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS16950 26532699ab00fc9a161d8b77938179ac 129 Pfam PF01850 PIN domain 3 119 4.3E-12 T 28-03-2018 IPR002716 PIN domain AFA_RS16950 26532699ab00fc9a161d8b77938179ac 129 SUPERFAMILY SSF88723 1 122 7.29E-25 T 28-03-2018 IPR029060 PIN domain-like AFA_RS16950 26532699ab00fc9a161d8b77938179ac 129 Gene3D G3DSA:3.40.50.1010 2 129 1.2E-17 T 28-03-2018 IPR029060 PIN domain-like AFA_RS12650 4f87dc4c1d8ccd310aae8df6547bfbde 486 SUPERFAMILY SSF111283 28 485 2.22E-131 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFA_RS12650 4f87dc4c1d8ccd310aae8df6547bfbde 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 1.1E-67 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFA_RS12650 4f87dc4c1d8ccd310aae8df6547bfbde 486 Gene3D G3DSA:3.30.2290.10 26 240 1.9E-54 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain AFA_RS12650 4f87dc4c1d8ccd310aae8df6547bfbde 486 PIRSF PIRSF004919 24 486 1.2E-134 T 28-03-2018 IPR025502 TldD AFA_RS13690 e5a6713cea9cd85debc5e2d8e4239d15 162 Pfam PF07811 TadE-like protein 16 53 3.3E-7 T 28-03-2018 IPR012495 TadE-like AFA_RS06360 5db512d62738cdfb0f14d31ec585851c 78 Gene3D G3DSA:1.10.10.60 8 37 1.6E-8 T 28-03-2018 AFA_RS06360 5db512d62738cdfb0f14d31ec585851c 78 Gene3D G3DSA:1.10.260.40 38 74 4.6E-4 T 28-03-2018 AFA_RS12490 9fa98049db38958c48f9f7185e4093d5 223 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 26 221 43.736 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS12490 9fa98049db38958c48f9f7185e4093d5 223 SUPERFAMILY SSF142695 28 198 4.45E-64 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS12490 9fa98049db38958c48f9f7185e4093d5 223 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 32 219 7.9E-78 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS12490 9fa98049db38958c48f9f7185e4093d5 223 Pfam PF00925 GTP cyclohydrolase II 33 195 1.4E-66 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AFA_RS12180 53a8559ab3204432bb0205af50684710 370 Pfam PF03524 Conjugal transfer protein 35 242 5.0E-53 T 28-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX AFA_RS10360 79ff4181b1a48bab28e250d19d4a33d7 408 SUPERFAMILY SSF89796 8 399 1.57E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS10360 79ff4181b1a48bab28e250d19d4a33d7 408 Gene3D G3DSA:3.40.50.10540 4 408 8.1E-139 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS10360 79ff4181b1a48bab28e250d19d4a33d7 408 Pfam PF02515 CoA-transferase family III 10 375 2.6E-119 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS01100 a01790d59eb67ca47c996e1c917c2ad7 354 Gene3D G3DSA:1.10.3470.10 36 334 5.2E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS01100 a01790d59eb67ca47c996e1c917c2ad7 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 329 3.5E-30 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 16 225 39.043 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 ProSitePatterns PS00474 Ribosomal protein L3 signature. 119 142 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 Pfam PF00297 Ribosomal protein L3 69 200 1.7E-19 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 SUPERFAMILY SSF50447 13 226 2.56E-78 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 18 222 4.1E-86 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18270 19a44e5f33abbd3f69017ea0967922ab 228 Gene3D G3DSA:4.10.960.10 61 183 1.6E-30 T 28-03-2018 AFA_RS12770 91747870e21b2048bdabe30d646510b9 323 Pfam PF02401 LytB protein 12 288 1.8E-93 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFA_RS12770 91747870e21b2048bdabe30d646510b9 323 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 10 292 38.391 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFA_RS12770 91747870e21b2048bdabe30d646510b9 323 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 12 290 4.5E-102 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFA_RS15695 1d9ce132a6094abf98d9bcf15f957e8c 386 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 365 5.5E-61 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 AFA_RS15695 1d9ce132a6094abf98d9bcf15f957e8c 386 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 368 2.2E-88 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 AFA_RS01615 fa26b35dd16c24faf445306fbb4b88ee 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 95 251 4.7E-7 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS01615 fa26b35dd16c24faf445306fbb4b88ee 256 SUPERFAMILY SSF56529 11 253 4.46E-34 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS01615 fa26b35dd16c24faf445306fbb4b88ee 256 Gene3D G3DSA:3.90.850.10 5 256 7.5E-20 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AFA_RS11715 ffcb7744c9803867641e524f09788841 232 Gene3D G3DSA:3.40.50.620 32 201 9.7E-5 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS11715 ffcb7744c9803867641e524f09788841 232 Pfam PF02677 Uncharacterized BCR, COG1636 19 193 1.1E-65 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH AFA_RS12965 c93fe7c51110c255e77b2d1675b8931d 111 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 6 97 1.8E-16 T 28-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 AFA_RS12965 c93fe7c51110c255e77b2d1675b8931d 111 PIRSF PIRSF020408 5 108 3.8E-40 T 28-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 AFA_RS02845 b526ec1f7495d568372b3daab919f955 216 Gene3D G3DSA:3.40.50.10070 31 185 2.6E-10 T 28-03-2018 AFA_RS02845 b526ec1f7495d568372b3daab919f955 216 Pfam PF05643 Putative bacterial lipoprotein (DUF799) 12 209 1.0E-85 T 28-03-2018 IPR008517 Protein of unknown function DUF799 AFA_RS07720 fc10fc15ac14d9dfd4024a001f8b85de 127 Gene3D G3DSA:3.90.1010.10 1 126 1.1E-30 T 28-03-2018 AFA_RS07720 fc10fc15ac14d9dfd4024a001f8b85de 127 Pfam PF01592 NifU-like N terminal domain 3 124 2.2E-34 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFA_RS07720 fc10fc15ac14d9dfd4024a001f8b85de 127 SUPERFAMILY SSF82649 1 124 8.11E-31 T 28-03-2018 AFA_RS11805 86486139a057f03a95307f6886f255f6 351 Gene3D G3DSA:3.20.20.300 11 341 1.1E-76 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFA_RS11805 86486139a057f03a95307f6886f255f6 351 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 13 350 50.977 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 AFA_RS11805 86486139a057f03a95307f6886f255f6 351 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 15 310 3.0E-73 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFA_RS11805 86486139a057f03a95307f6886f255f6 351 SUPERFAMILY SSF51445 13 317 9.69E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily AFA_RS08520 267375ee9217b8c5f229461856c4ec27 90 Gene3D G3DSA:3.90.56.10 1 89 3.9E-34 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 AFA_RS08520 267375ee9217b8c5f229461856c4ec27 90 SUPERFAMILY SSF56029 3 89 1.28E-29 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 AFA_RS08520 267375ee9217b8c5f229461856c4ec27 90 ProDom PD004249 MONOOXYGENASE COMPONENT HYDROXYLASE MMOB/DMPM PHENOL SUBUNIT 3D-STRUCTURE HYDROCARBONS IRON PHENOLHYDROXYLASE 9 88 2.0E-28 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 AFA_RS08520 267375ee9217b8c5f229461856c4ec27 90 Pfam PF02406 MmoB/DmpM family 4 86 5.6E-29 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 335 34.697 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 Gene3D G3DSA:1.10.240.10 211 330 3.4E-23 T 28-03-2018 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 Gene3D G3DSA:3.40.50.620 1 210 2.3E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 SUPERFAMILY SSF160113 352 401 6.54E-8 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 2.8E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 204 214 2.8E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 2.8E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 2.8E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 SUPERFAMILY SSF52374 4 334 2.2E-76 T 28-03-2018 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 Pfam PF00579 tRNA synthetases class I (W and Y) 3 245 5.0E-52 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFA_RS04910 2549b75238fa1f86998e4cd639237a4d 440 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 334 8.2E-90 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.5E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 28-03-2018 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 Pfam PF00444 Ribosomal protein L36 1 37 1.1E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.047 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS17990 34c4866f4d8d4cb8a25b9d0166611ec3 37 SUPERFAMILY SSF57840 1 37 1.31E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS06310 8fba7c846778829e854b7ef089818ba9 108 SMART SM00530 11 64 1.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS06310 8fba7c846778829e854b7ef089818ba9 108 Pfam PF01381 Helix-turn-helix 12 61 5.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFA_RS06310 8fba7c846778829e854b7ef089818ba9 108 Gene3D G3DSA:1.10.260.40 2 98 1.9E-12 T 28-03-2018 AFA_RS06310 8fba7c846778829e854b7ef089818ba9 108 SUPERFAMILY SSF47413 4 66 1.86E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AFA_RS06475 0f3d5974cf0b67383e92f2d5cf8d3bd8 205 Gene3D G3DSA:3.40.30.10 40 204 3.9E-35 T 28-03-2018 AFA_RS06475 0f3d5974cf0b67383e92f2d5cf8d3bd8 205 Pfam PF02630 SCO1/SenC 44 182 2.6E-40 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS06475 0f3d5974cf0b67383e92f2d5cf8d3bd8 205 SUPERFAMILY SSF52833 46 200 2.28E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS09030 910a9957b7c4c45c3340ba61db7befea 366 Gene3D G3DSA:3.20.20.70 2 360 3.0E-117 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS09030 910a9957b7c4c45c3340ba61db7befea 366 SUPERFAMILY SSF51395 3 351 7.59E-117 T 28-03-2018 AFA_RS09030 910a9957b7c4c45c3340ba61db7befea 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 328 4.0E-84 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFA_RS07190 98ada15362232b4fb3789ff154c26a08 386 SUPERFAMILY SSF53822 28 384 4.52E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS07190 98ada15362232b4fb3789ff154c26a08 386 Gene3D G3DSA:3.40.50.2300 13 152 1.9E-18 T 28-03-2018 AFA_RS07190 98ada15362232b4fb3789ff154c26a08 386 Gene3D G3DSA:3.40.50.2300 153 314 1.0E-33 T 28-03-2018 AFA_RS07190 98ada15362232b4fb3789ff154c26a08 386 Pfam PF13458 Periplasmic binding protein 27 365 4.9E-50 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS11000 3d1b6261874bc36710c9496631954a64 146 Gene3D G3DSA:1.10.10.10 50 95 5.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11000 3d1b6261874bc36710c9496631954a64 146 Hamap MF_01114 Regulatory protein RecX [recX]. 2 145 12.606 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 AFA_RS11000 3d1b6261874bc36710c9496631954a64 146 Gene3D G3DSA:1.10.10.10 96 143 6.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11000 3d1b6261874bc36710c9496631954a64 146 Gene3D G3DSA:1.10.10.10 1 48 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11000 3d1b6261874bc36710c9496631954a64 146 Pfam PF02631 RecX family 26 140 6.4E-25 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 AFA_RS00480 7a70a60e49153d1b721b93da6999d7de 280 SUPERFAMILY SSF53850 31 262 2.38E-60 T 28-03-2018 AFA_RS00480 7a70a60e49153d1b721b93da6999d7de 280 Gene3D G3DSA:3.40.190.10 148 265 3.4E-28 T 28-03-2018 AFA_RS00480 7a70a60e49153d1b721b93da6999d7de 280 Pfam PF03180 NLPA lipoprotein 31 262 5.6E-66 T 28-03-2018 IPR004872 Lipoprotein NlpA family AFA_RS00480 7a70a60e49153d1b721b93da6999d7de 280 Gene3D G3DSA:3.40.190.10 30 147 6.1E-30 T 28-03-2018 AFA_RS06810 b06dcbff947206e4736626c18fbf0691 136 Pfam PF05772 NinB protein 3 128 4.9E-44 T 28-03-2018 IPR008711 Recombinase NinB AFA_RS06810 b06dcbff947206e4736626c18fbf0691 136 Gene3D G3DSA:1.10.3790.10 1 132 1.6E-31 T 28-03-2018 IPR008711 Recombinase NinB AFA_RS06810 b06dcbff947206e4736626c18fbf0691 136 SUPERFAMILY SSF103370 1 128 1.57E-37 T 28-03-2018 IPR008711 Recombinase NinB AFA_RS12415 4e82a444e98974cbbd1a4caa5604d950 554 Pfam PF00474 Sodium:solute symporter family 58 473 5.1E-110 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS12415 4e82a444e98974cbbd1a4caa5604d950 554 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 58 472 1.1E-58 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS12415 4e82a444e98974cbbd1a4caa5604d950 554 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 173 198 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AFA_RS14310 ce15fc0d61d91297f94117bab211ff84 249 Pfam PF01925 Sulfite exporter TauE/SafE 9 238 2.3E-24 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS11235 ee0dbecdcb858e92a2f07d0f02c58a8e 328 Gene3D G3DSA:3.30.70.920 61 155 9.0E-4 T 28-03-2018 AFA_RS11235 ee0dbecdcb858e92a2f07d0f02c58a8e 328 Gene3D G3DSA:3.30.70.920 219 322 1.0E-13 T 28-03-2018 AFA_RS11235 ee0dbecdcb858e92a2f07d0f02c58a8e 328 Gene3D G3DSA:1.10.10.10 1 58 0.063 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS02320 3578473ae6b16ef83b327dc5e415af92 213 SUPERFAMILY SSF109604 21 212 1.46E-54 T 28-03-2018 AFA_RS02320 3578473ae6b16ef83b327dc5e415af92 213 Pfam PF01966 HD domain 31 132 4.5E-10 T 28-03-2018 IPR006674 HD domain AFA_RS02320 3578473ae6b16ef83b327dc5e415af92 213 Gene3D G3DSA:1.10.3210.10 2 213 4.4E-20 T 28-03-2018 AFA_RS02320 3578473ae6b16ef83b327dc5e415af92 213 SMART SM00471 25 142 0.0015 T 28-03-2018 IPR003607 HD/PDEase domain AFA_RS14370 b95d7d543bf83e789f9539221aa08afa 129 SUPERFAMILY SSF52833 21 105 8.86E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS14370 b95d7d543bf83e789f9539221aa08afa 129 Pfam PF00085 Thioredoxin 21 87 1.8E-11 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 AFA_RS14370 b95d7d543bf83e789f9539221aa08afa 129 Gene3D G3DSA:3.40.30.10 8 116 2.3E-14 T 28-03-2018 AFA_RS02780 a28988514b690c81c766a644ea5350c8 318 Gene3D G3DSA:3.60.15.10 11 241 1.9E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS02780 a28988514b690c81c766a644ea5350c8 318 Pfam PF00753 Metallo-beta-lactamase superfamily 33 195 1.0E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS02780 a28988514b690c81c766a644ea5350c8 318 SUPERFAMILY SSF56281 16 310 4.06E-56 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS02780 a28988514b690c81c766a644ea5350c8 318 SMART SM00849 33 220 2.7E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS16450 b07f9d5aacb73fa113bba003a45f8048 332 PIRSF PIRSF017082 2 332 7.6E-76 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS16450 b07f9d5aacb73fa113bba003a45f8048 332 Gene3D G3DSA:3.40.190.10 132 262 1.5E-13 T 28-03-2018 AFA_RS16450 b07f9d5aacb73fa113bba003a45f8048 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 329 4.2E-77 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS16450 b07f9d5aacb73fa113bba003a45f8048 332 SUPERFAMILY SSF53850 122 298 4.04E-13 T 28-03-2018 AFA_RS05190 22c317580de2d434d5c3ab843596b45d 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 11 263 2.4E-82 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFA_RS05190 22c317580de2d434d5c3ab843596b45d 267 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 11 267 33.146 T 28-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFA_RS05190 22c317580de2d434d5c3ab843596b45d 267 Gene3D G3DSA:3.10.270.10 10 266 1.3E-91 T 28-03-2018 AFA_RS18555 b25d43e313129394f5e300c6bcb0acfe 346 SUPERFAMILY SSF144052 20 336 2.09E-15 T 28-03-2018 AFA_RS01525 3f521e98b6f24d5d670b8d0dd329b869 377 SUPERFAMILY SSF53807 25 344 2.2E-40 T 28-03-2018 AFA_RS01525 3f521e98b6f24d5d670b8d0dd329b869 377 Gene3D G3DSA:3.40.50.1980 18 164 1.9E-23 T 28-03-2018 AFA_RS01525 3f521e98b6f24d5d670b8d0dd329b869 377 Pfam PF01497 Periplasmic binding protein 80 314 7.1E-17 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 AFA_RS01525 3f521e98b6f24d5d670b8d0dd329b869 377 Gene3D G3DSA:3.40.50.1980 165 348 2.0E-31 T 28-03-2018 AFA_RS04475 d04def88bf8d88a67c2fce799e9970d6 234 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 8 216 1.1E-46 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 AFA_RS04475 d04def88bf8d88a67c2fce799e9970d6 234 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 8 216 1.4E-47 T 28-03-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 AFA_RS12580 38e87fffa996e825d456d7f88f809059 695 Pfam PF02554 Carbon starvation protein CstA 37 414 5.9E-174 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 AFA_RS12580 38e87fffa996e825d456d7f88f809059 695 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 468 596 3.5E-35 T 28-03-2018 IPR025299 CstA, C-terminal domain AFA_RS16410 2366b772e9c8d76b248cb64cc92c1a4d 257 SUPERFAMILY SSF69572 2 246 2.09E-85 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS16410 2366b772e9c8d76b248cb64cc92c1a4d 257 Pfam PF00899 ThiF family 9 243 1.4E-63 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS16410 2366b772e9c8d76b248cb64cc92c1a4d 257 Gene3D G3DSA:3.40.50.720 1 248 8.6E-73 T 28-03-2018 AFA_RS15250 aaa76aabf23ae36ce80d5113e697acf9 104 Pfam PF13767 Domain of unknown function (DUF4168) 23 99 2.5E-16 T 28-03-2018 IPR025433 Domain of unknown function DUF4168 AFA_RS11380 0ebfc46d6340ee1d6f1fd566e029926f 180 SUPERFAMILY SSF55729 16 172 3.33E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS11380 0ebfc46d6340ee1d6f1fd566e029926f 180 Pfam PF00583 Acetyltransferase (GNAT) family 40 145 5.5E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS11380 0ebfc46d6340ee1d6f1fd566e029926f 180 Gene3D G3DSA:3.40.630.30 15 177 9.9E-33 T 28-03-2018 AFA_RS13265 ad7cbda44d15b997cb15397b04dc57cb 188 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 2 179 18.229 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 AFA_RS13265 ad7cbda44d15b997cb15397b04dc57cb 188 Pfam PF04279 Intracellular septation protein A 3 178 2.3E-62 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 AFA_RS13265 ad7cbda44d15b997cb15397b04dc57cb 188 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 3 178 4.6E-54 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 Gene3D G3DSA:1.10.10.10 1 84 6.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 Gene3D G3DSA:3.40.190.10 89 175 4.7E-10 T 28-03-2018 AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 SUPERFAMILY SSF53850 88 296 6.88E-40 T 28-03-2018 AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 Gene3D G3DSA:3.40.190.10 176 265 6.3E-22 T 28-03-2018 AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 SUPERFAMILY SSF46785 1 111 8.33E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS12480 4a9fdf407c7686ac4118d4cc86dfb151 302 Pfam PF03466 LysR substrate binding domain 88 295 1.7E-39 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 SMART SM00382 28 215 1.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 Gene3D G3DSA:3.40.50.300 1 242 1.5E-76 T 28-03-2018 AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 SUPERFAMILY SSF52540 3 237 8.47E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 PIRSF PIRSF039085 1 242 2.8E-109 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFA_RS03785 f4165982fde704a1ed3f5c649f002193 242 Pfam PF00005 ABC transporter 19 167 3.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 Gene3D G3DSA:3.30.420.150 130 310 2.8E-34 T 28-03-2018 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 SUPERFAMILY SSF109604 310 486 1.19E-36 T 28-03-2018 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 SUPERFAMILY SSF53067 5 129 2.22E-31 T 28-03-2018 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 Pfam PF02541 Ppx/GppA phosphatase family 22 305 1.2E-70 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 SUPERFAMILY SSF53067 134 305 1.06E-41 T 28-03-2018 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 Gene3D G3DSA:3.30.420.40 1 129 6.3E-37 T 28-03-2018 AFA_RS04190 061d17b0314496034fc502f6f8af9b9f 496 PIRSF PIRSF001267 1 495 1.1E-174 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 SUPERFAMILY SSF69572 7 324 7.46E-95 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 Gene3D G3DSA:3.40.250.10 272 388 5.3E-21 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 SUPERFAMILY SSF52821 291 384 3.16E-10 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 Gene3D G3DSA:3.40.50.720 10 259 7.9E-67 T 28-03-2018 AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 Pfam PF00581 Rhodanese-like domain 290 381 2.4E-10 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 Pfam PF00899 ThiF family 21 256 1.9E-59 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFA_RS08160 dad528dd0855d7e36e2e75def3401884 390 SMART SM00450 288 385 6.2E-17 T 28-03-2018 IPR001763 Rhodanese-like domain AFA_RS18020 38abbe0e039bd98500f197b5e7abaa60 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 9.0E-35 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18020 38abbe0e039bd98500f197b5e7abaa60 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 2.6E-36 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS18020 38abbe0e039bd98500f197b5e7abaa60 117 Gene3D G3DSA:3.30.420.100 1 117 1.4E-37 T 28-03-2018 AFA_RS18020 38abbe0e039bd98500f197b5e7abaa60 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 25.487 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFA_RS18020 38abbe0e039bd98500f197b5e7abaa60 117 SUPERFAMILY SSF53137 3 115 3.05E-50 T 28-03-2018 AFA_RS11420 70119c739b1df92866e28b0f68473d36 262 SUPERFAMILY SSF56317 1 254 6.41E-66 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS11420 70119c739b1df92866e28b0f68473d36 262 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 3.0E-43 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS11420 70119c739b1df92866e28b0f68473d36 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site AFA_RS11420 70119c739b1df92866e28b0f68473d36 262 Gene3D G3DSA:3.60.110.10 1 260 1.0E-64 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AFA_RS00315 2137ee15c18fd2ba9df02f1e3b9837b3 393 SUPERFAMILY SSF53901 25 125 1.21E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00315 2137ee15c18fd2ba9df02f1e3b9837b3 393 SUPERFAMILY SSF53901 186 364 1.21E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00315 2137ee15c18fd2ba9df02f1e3b9837b3 393 Gene3D G3DSA:3.40.47.10 11 236 5.0E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS00315 2137ee15c18fd2ba9df02f1e3b9837b3 393 PIRSF PIRSF000429 10 378 5.1E-17 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS00315 2137ee15c18fd2ba9df02f1e3b9837b3 393 Gene3D G3DSA:3.40.47.10 237 390 4.2E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS12645 b35f5395057d12fcd765801cb7f3ea26 303 SUPERFAMILY SSF103481 192 289 3.01E-6 T 28-03-2018 AFA_RS12645 b35f5395057d12fcd765801cb7f3ea26 303 Pfam PF00892 EamA-like transporter family 162 286 2.0E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS12645 b35f5395057d12fcd765801cb7f3ea26 303 Pfam PF00892 EamA-like transporter family 8 138 1.9E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS12645 b35f5395057d12fcd765801cb7f3ea26 303 SUPERFAMILY SSF103481 44 140 9.68E-7 T 28-03-2018 AFA_RS17060 e4a988f2bbce74f0b975ca85bf6f0e82 304 SUPERFAMILY SSF103481 198 294 8.37E-13 T 28-03-2018 AFA_RS17060 e4a988f2bbce74f0b975ca85bf6f0e82 304 Pfam PF00892 EamA-like transporter family 23 149 2.2E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS17060 e4a988f2bbce74f0b975ca85bf6f0e82 304 Pfam PF00892 EamA-like transporter family 162 294 1.7E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS17060 e4a988f2bbce74f0b975ca85bf6f0e82 304 SUPERFAMILY SSF103481 55 152 7.85E-15 T 28-03-2018 AFA_RS02690 39d67f2219a25da82762f253ea1b387d 263 SUPERFAMILY SSF53639 25 218 1.63E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02690 39d67f2219a25da82762f253ea1b387d 263 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 211 4.7E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02690 39d67f2219a25da82762f253ea1b387d 263 SMART SM01007 31 211 1.6E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS02690 39d67f2219a25da82762f253ea1b387d 263 Gene3D G3DSA:3.40.225.10 17 263 1.5E-76 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS09580 89f92750d7d32c4cade0cf5f838a0533 83 Pfam PF11660 Protein of unknown function (DUF3262) 13 82 4.5E-13 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 AFA_RS09580 89f92750d7d32c4cade0cf5f838a0533 83 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 13 82 3.3E-12 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 SUPERFAMILY SSF143975 4 377 5.89E-122 T 28-03-2018 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 Pfam PF00920 Dehydratase family 36 553 3.2E-188 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 556 7.0E-187 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 SUPERFAMILY SSF52016 378 556 1.18E-53 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS17315 4c560c41225f40ee16ef673a7d558580 570 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 556 42.242 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFA_RS18445 8ec7ddcfcbc3c484c0354c44bd10ee81 326 Pfam PF13387 Domain of unknown function (DUF4105) 116 269 3.1E-44 T 28-03-2018 IPR025178 Domain of unknown function DUF4105 AFA_RS00050 8dcaa29a676adb8f4ac18b8cd3a8ea0b 303 SMART SM00849 58 275 2.0E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00050 8dcaa29a676adb8f4ac18b8cd3a8ea0b 303 Gene3D G3DSA:3.60.15.10 4 287 2.9E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00050 8dcaa29a676adb8f4ac18b8cd3a8ea0b 303 Pfam PF00753 Metallo-beta-lactamase superfamily 61 275 7.8E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS00050 8dcaa29a676adb8f4ac18b8cd3a8ea0b 303 SUPERFAMILY SSF56281 57 292 1.31E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS02285 2e3f9a090f82debae0e2a80c33da078d 269 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 251 32.574 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AFA_RS02285 2e3f9a090f82debae0e2a80c33da078d 269 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 3.3E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFA_RS02285 2e3f9a090f82debae0e2a80c33da078d 269 Gene3D G3DSA:3.60.21.10 1 256 1.8E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS02285 2e3f9a090f82debae0e2a80c33da078d 269 SUPERFAMILY SSF56300 1 259 1.26E-52 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS18195 c6eb04593552846ac201037aa831636f 249 Gene3D G3DSA:1.10.3720.10 4 249 6.2E-20 T 28-03-2018 AFA_RS18195 c6eb04593552846ac201037aa831636f 249 SUPERFAMILY SSF161098 52 237 4.45E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS18195 c6eb04593552846ac201037aa831636f 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 249 6.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS10070 b77e58b67885e1801f8058d7c88505a6 335 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 15 332 2.2E-84 T 28-03-2018 IPR003770 Endolytic murein transglycosylase AFA_RS10070 b77e58b67885e1801f8058d7c88505a6 335 Gene3D G3DSA:3.30.160.60 76 109 9.9E-6 T 28-03-2018 AFA_RS10070 b77e58b67885e1801f8058d7c88505a6 335 Gene3D G3DSA:3.30.160.60 304 335 9.8E-11 T 28-03-2018 AFA_RS10070 b77e58b67885e1801f8058d7c88505a6 335 Pfam PF02618 YceG-like family 45 330 4.9E-79 T 28-03-2018 IPR003770 Endolytic murein transglycosylase AFA_RS10070 b77e58b67885e1801f8058d7c88505a6 335 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 12 335 33.144 T 28-03-2018 IPR003770 Endolytic murein transglycosylase AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 SMART SM00788 8 428 4.1E-290 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 Gene3D G3DSA:3.90.170.10 271 435 1.1E-65 T 28-03-2018 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 SUPERFAMILY SSF52540 7 433 3.87E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 Pfam PF00709 Adenylosuccinate synthetase 10 427 1.1E-173 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 Gene3D G3DSA:3.40.440.10 5 155 1.0E-53 T 28-03-2018 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 Gene3D G3DSA:3.40.440.10 156 270 1.1E-24 T 28-03-2018 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 435 206.827 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 10 433 2.1E-174 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 137 148 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS11515 9a8dbc24e747aae0de7bd090a1bb90b0 435 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 15 22 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFA_RS02795 da4ca93f8074ee5c80f1efd7f40ba55e 198 Pfam PF03550 Outer membrane lipoprotein LolB 46 198 5.5E-32 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 AFA_RS02795 da4ca93f8074ee5c80f1efd7f40ba55e 198 SUPERFAMILY SSF89392 23 198 7.85E-27 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFA_RS02795 da4ca93f8074ee5c80f1efd7f40ba55e 198 Gene3D G3DSA:2.50.20.10 24 198 1.9E-30 T 28-03-2018 AFA_RS15520 421000bca488e69d86bae1e6c4a45b00 225 Gene3D G3DSA:1.10.287.620 24 103 1.7E-4 T 28-03-2018 AFA_RS10305 ab2a9c0ec72724a87f6dee83e2697c5f 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 187 383 1.1E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain AFA_RS10305 ab2a9c0ec72724a87f6dee83e2697c5f 404 Gene3D G3DSA:3.40.50.1110 176 400 2.0E-23 T 28-03-2018 AFA_RS10305 ab2a9c0ec72724a87f6dee83e2697c5f 404 SUPERFAMILY SSF52266 181 388 1.98E-38 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain AFA_RS05650 e384ed5481a0af4d6899b2c51169f17e 351 Pfam PF03601 Conserved hypothetical protein 698 31 329 1.1E-82 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 Gene3D G3DSA:3.40.50.720 2 179 1.0E-33 T 28-03-2018 AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 Gene3D G3DSA:3.40.50.720 180 240 0.0092 T 28-03-2018 AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 SUPERFAMILY SSF51735 7 231 4.38E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS07745 2616e4217995ca0f06da9bae45506594 245 Pfam PF00106 short chain dehydrogenase 8 194 4.0E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS05735 6a3cf1e4073bb59b4e85a910c947d2c6 291 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 237 1.3E-11 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AFA_RS05735 6a3cf1e4073bb59b4e85a910c947d2c6 291 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 282 2.1E-115 T 28-03-2018 IPR022522 Flagellar motor stator, MotA AFA_RS05735 6a3cf1e4073bb59b4e85a910c947d2c6 291 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site AFA_RS05730 2a62cfd392cb9e55f188fba5c9cd4063 216 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 178 4.1E-78 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 AFA_RS05730 2a62cfd392cb9e55f188fba5c9cd4063 216 SUPERFAMILY SSF160930 6 166 9.15E-57 T 28-03-2018 AFA_RS05730 2a62cfd392cb9e55f188fba5c9cd4063 216 PIRSF PIRSF003159 1 187 1.6E-76 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 AFA_RS05730 2a62cfd392cb9e55f188fba5c9cd4063 216 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 200 43.511 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 AFA_RS05730 2a62cfd392cb9e55f188fba5c9cd4063 216 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 170 3.0E-66 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 AFA_RS18580 04adff225d5d1e2fd71c59efceb69280 129 Gene3D G3DSA:3.10.180.10 1 129 4.7E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS18580 04adff225d5d1e2fd71c59efceb69280 129 SUPERFAMILY SSF54593 1 127 5.91E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS18580 04adff225d5d1e2fd71c59efceb69280 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 8.8E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS03960 0e014c1337a5afe84ea618af3691fb72 166 Gene3D G3DSA:3.40.50.300 3 162 8.0E-45 T 28-03-2018 AFA_RS03960 0e014c1337a5afe84ea618af3691fb72 166 SUPERFAMILY SSF52540 34 140 1.4E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS03960 0e014c1337a5afe84ea618af3691fb72 166 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 148 8.7E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFA_RS03960 0e014c1337a5afe84ea618af3691fb72 166 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 136 5.0E-35 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 Gene3D G3DSA:1.10.1660.10 1 66 2.8E-12 T 28-03-2018 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 50 1.0E-13 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 SUPERFAMILY SSF52172 81 203 1.2E-19 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 SUPERFAMILY SSF46955 5 57 5.95E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 SMART SM00448 81 196 4.5E-8 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 Gene3D G3DSA:3.40.50.2300 76 205 1.7E-16 T 28-03-2018 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 Pfam PF12728 Helix-turn-helix domain 5 55 6.7E-13 T 28-03-2018 AFA_RS12460 8c6e4bd2b463d0baff117273547008fa 207 Pfam PF00072 Response regulator receiver domain 83 195 5.9E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS12605 8178b2bab1a23200b424fbd7dc08b1e8 203 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 8 194 8.4E-78 T 28-03-2018 IPR018715 Protein of unknown function DUF2239 AFA_RS14390 1c213b0306cf42b1e36fa6d1583c784d 70 Gene3D G3DSA:2.60.260.40 8 62 3.6E-19 T 28-03-2018 AFA_RS14390 1c213b0306cf42b1e36fa6d1583c784d 70 Pfam PF10276 Zinc-finger domain 25 59 1.8E-10 T 28-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 8.4E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 8.4E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 8.4E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 3.1E-37 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 SUPERFAMILY SSF47729 1 91 4.56E-28 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 Gene3D G3DSA:4.10.520.10 1 94 7.2E-28 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.9E-26 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS11955 6447f50f6cbb82c0a8ade92011a0f730 119 SMART SM00411 1 91 2.9E-36 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 Pfam PF00572 Ribosomal protein L13 15 138 9.2E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 Gene3D G3DSA:3.90.1180.10 1 142 1.7E-61 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.136 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 SUPERFAMILY SSF52161 1 139 3.4E-59 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 2.5E-62 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFA_RS15535 158fe76ea4b25bac4b6cf69ac98f7d84 142 PIRSF PIRSF002181 1 142 1.8E-49 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFA_RS00815 af1901de8a277ac866f37654a5be24f1 89 Pfam PF04324 BFD-like [2Fe-2S] binding domain 3 49 6.1E-9 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFA_RS11445 9627c3e399b80f3370d25492594bce36 62 Pfam PF11450 Protein of unknwon function (DUF3008) 3 61 5.5E-25 T 28-03-2018 IPR021553 Protein of unknwon function DUF3008 AFA_RS13730 b0f21572fb8c56408d8d81493c9e6435 243 Gene3D G3DSA:1.10.1280.10 1 81 6.6E-4 T 28-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 AFA_RS17300 d1834e19a49a143f096c4a803f5111c6 315 Gene3D G3DSA:3.90.25.10 188 286 1.1E-24 T 28-03-2018 AFA_RS17300 d1834e19a49a143f096c4a803f5111c6 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 202 7.0E-22 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS17300 d1834e19a49a143f096c4a803f5111c6 315 SUPERFAMILY SSF51735 1 275 5.79E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS17300 d1834e19a49a143f096c4a803f5111c6 315 Gene3D G3DSA:3.40.50.720 2 187 1.7E-26 T 28-03-2018 AFA_RS07765 c4f4e71b877881d7314fcca8a9f95175 303 SUPERFAMILY SSF103481 46 146 1.26E-13 T 28-03-2018 AFA_RS07765 c4f4e71b877881d7314fcca8a9f95175 303 Pfam PF00892 EamA-like transporter family 160 300 5.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS07765 c4f4e71b877881d7314fcca8a9f95175 303 Pfam PF00892 EamA-like transporter family 15 145 5.5E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS07765 c4f4e71b877881d7314fcca8a9f95175 303 SUPERFAMILY SSF103481 211 302 6.28E-13 T 28-03-2018 AFA_RS01310 58421b05c239d0bd6e55e2ae2d6aca0e 331 Gene3D G3DSA:3.20.20.150 8 329 1.8E-16 T 28-03-2018 AFA_RS01310 58421b05c239d0bd6e55e2ae2d6aca0e 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFA_RS01310 58421b05c239d0bd6e55e2ae2d6aca0e 331 Pfam PF01136 Peptidase family U32 75 330 9.3E-70 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFA_RS03965 d7c9aacd4843bc310036473892657317 298 Pfam PF03547 Membrane transport protein 154 294 2.4E-10 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AFA_RS03965 d7c9aacd4843bc310036473892657317 298 Pfam PF03547 Membrane transport protein 8 130 4.6E-7 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 Gene3D G3DSA:1.20.1250.20 206 399 9.2E-9 T 28-03-2018 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 389 1.8E-80 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 Pfam PF07690 Major Facilitator Superfamily 19 361 1.7E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 SUPERFAMILY SSF103473 5 402 5.89E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS17845 94a29231583362efa7908f503defbbb0 411 PRINTS PR01035 Tetracycline resistance protein signature 54 73 1.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 PRINTS PR01035 Tetracycline resistance protein signature 24 40 1.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 PRINTS PR01035 Tetracycline resistance protein signature 296 317 1.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFA_RS17845 94a29231583362efa7908f503defbbb0 411 Gene3D G3DSA:1.20.1250.20 5 198 6.0E-31 T 28-03-2018 AFA_RS14350 112ada475fcc845644c32c84b900afcd 199 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 6.2E-18 T 28-03-2018 IPR010127 Phasin, subfamily 1 AFA_RS14350 112ada475fcc845644c32c84b900afcd 199 Pfam PF09361 Phasin protein 8 104 6.6E-20 T 28-03-2018 IPR018968 Phasin AFA_RS01495 e450af2580671f776caef097b587a62b 261 Gene3D G3DSA:1.10.3720.10 10 253 3.4E-25 T 28-03-2018 AFA_RS01495 e450af2580671f776caef097b587a62b 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 247 1.5E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS01495 e450af2580671f776caef097b587a62b 261 SUPERFAMILY SSF161098 53 240 3.66E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS13780 9fdc9333224edbe3325ceee5325b2acc 151 Gene3D G3DSA:1.10.10.10 3 81 2.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13780 9fdc9333224edbe3325ceee5325b2acc 151 Pfam PF01475 Ferric uptake regulator family 10 132 8.1E-42 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFA_RS13780 9fdc9333224edbe3325ceee5325b2acc 151 Gene3D G3DSA:2.20.70.10 82 102 0.0036 T 28-03-2018 AFA_RS13780 9fdc9333224edbe3325ceee5325b2acc 151 SUPERFAMILY SSF46785 4 136 4.42E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS07775 f0ec60f7caf4d47b14ff6bd23d8f0825 304 Pfam PF00892 EamA-like transporter family 12 142 9.5E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS07775 f0ec60f7caf4d47b14ff6bd23d8f0825 304 Pfam PF00892 EamA-like transporter family 161 297 5.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS07775 f0ec60f7caf4d47b14ff6bd23d8f0825 304 SUPERFAMILY SSF103481 44 143 2.35E-13 T 28-03-2018 AFA_RS07775 f0ec60f7caf4d47b14ff6bd23d8f0825 304 SUPERFAMILY SSF103481 211 300 3.14E-12 T 28-03-2018 AFA_RS07910 a003eb8da2f615f119eff508f21148e3 255 Gene3D G3DSA:3.40.50.360 29 227 2.4E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS07910 a003eb8da2f615f119eff508f21148e3 255 Pfam PF03358 NADPH-dependent FMN reductase 36 179 4.9E-26 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFA_RS07910 a003eb8da2f615f119eff508f21148e3 255 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 29 227 8.1E-112 T 28-03-2018 IPR014063 Arsenate resistance ArsH AFA_RS07910 a003eb8da2f615f119eff508f21148e3 255 SUPERFAMILY SSF52218 3 231 4.4E-62 T 28-03-2018 IPR029039 Flavoprotein-like domain AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 45.744 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 2.3E-49 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 4.9E-47 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 SUPERFAMILY SSF53098 1 155 4.3E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 Gene3D G3DSA:3.30.420.10 1 157 6.4E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.4E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 3.4E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 3.4E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 3.4E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS14440 1a08b5d428f682fca6f44e1ca2daa822 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 3.4E-31 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFA_RS08425 34ca2556a7856db86467194a60e17aaa 57 Pfam PF07411 Domain of unknown function (DUF1508) 8 56 1.4E-22 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 AFA_RS08425 34ca2556a7856db86467194a60e17aaa 57 SUPERFAMILY SSF160113 1 56 5.89E-20 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 AFA_RS08425 34ca2556a7856db86467194a60e17aaa 57 Gene3D G3DSA:3.30.160.160 3 48 1.0E-20 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 AFA_RS14140 6735dba97d2f6a5896fad76364c38c0d 160 Pfam PF02293 AmiS/UreI family transporter 1 158 1.2E-45 T 28-03-2018 IPR003211 AmiS/UreI transporter GO:0006810|GO:0016020 AFA_RS06420 b686bf6047a7e527297d90c80560f266 377 Gene3D G3DSA:3.90.1150.10 263 375 2.6E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS06420 b686bf6047a7e527297d90c80560f266 377 PIRSF PIRSF000524 13 377 4.4E-41 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 AFA_RS06420 b686bf6047a7e527297d90c80560f266 377 Gene3D G3DSA:3.40.640.10 13 262 1.3E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS06420 b686bf6047a7e527297d90c80560f266 377 Pfam PF00266 Aminotransferase class-V 21 310 2.5E-16 T 28-03-2018 IPR000192 Aminotransferase class V domain AFA_RS06420 b686bf6047a7e527297d90c80560f266 377 SUPERFAMILY SSF53383 10 373 5.08E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 PIRSF PIRSF002786 1 166 1.4E-29 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 PIRSF PIRSF002786 161 286 4.2E-21 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 Pfam PF03934 Type II secretion system (T2SS), protein K 175 280 1.9E-23 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 Pfam PF03934 Type II secretion system (T2SS), protein K 32 154 1.8E-21 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 Gene3D G3DSA:3.30.1300.30 27 150 1.5E-19 T 28-03-2018 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 Gene3D G3DSA:1.10.40.60 191 249 3.0E-6 T 28-03-2018 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 SUPERFAMILY SSF54523 250 283 5.49E-7 T 28-03-2018 AFA_RS14270 9759a4ceb8de36bec68d9b4f3c48105d 286 SUPERFAMILY SSF54523 43 107 5.49E-7 T 28-03-2018 AFA_RS13350 a88e51660b1cd8cbf83ac64f18a5c7a1 177 Pfam PF10993 Protein of unknown function (DUF2818) 6 65 9.6E-6 T 28-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane AFA_RS13350 a88e51660b1cd8cbf83ac64f18a5c7a1 177 Pfam PF10993 Protein of unknown function (DUF2818) 106 170 8.1E-20 T 28-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane AFA_RS04880 fefe2c6d2eea611382754cc1a594753f 587 Pfam PF02652 L-lactate permease 6 548 3.0E-105 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFA_RS02405 802f946ac1a732eceaea3290b290b6a1 370 Gene3D G3DSA:3.20.20.70 15 369 2.1E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS02405 802f946ac1a732eceaea3290b290b6a1 370 SUPERFAMILY SSF51395 15 367 1.04E-88 T 28-03-2018 AFA_RS02405 802f946ac1a732eceaea3290b290b6a1 370 PIRSF PIRSF000138 8 370 1.7E-118 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 AFA_RS02405 802f946ac1a732eceaea3290b290b6a1 370 Pfam PF01070 FMN-dependent dehydrogenase 26 367 1.4E-120 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 Gene3D G3DSA:3.40.50.1000 76 217 1.4E-34 T 28-03-2018 IPR023214 HAD-like domain AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 6 184 4.8E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 184 3.0E-34 T 28-03-2018 IPR023214 HAD-like domain AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 Gene3D G3DSA:1.10.150.240 20 75 2.8E-11 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 178 2.2E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AFA_RS13165 a763674cc0b2f1a903b2873654a50141 217 SUPERFAMILY SSF56784 2 213 1.6E-54 T 28-03-2018 IPR023214 HAD-like domain AFA_RS05245 7b0333f157b251d376606be1fcbdb27b 395 Gene3D G3DSA:3.40.640.10 40 277 9.3E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS05245 7b0333f157b251d376606be1fcbdb27b 395 Pfam PF00155 Aminotransferase class I and II 31 377 1.7E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFA_RS05245 7b0333f157b251d376606be1fcbdb27b 395 SUPERFAMILY SSF53383 2 389 5.38E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS05245 7b0333f157b251d376606be1fcbdb27b 395 Gene3D G3DSA:3.90.1150.10 278 392 7.4E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 AFA_RS06995 473e4129737483af7f5009958aa16a51 144 Gene3D G3DSA:3.40.1440.10 21 140 0.0011 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily AFA_RS12945 c898b3498336394c7b01c0e95c479082 313 SUPERFAMILY SSF103481 202 308 2.62E-15 T 28-03-2018 AFA_RS12945 c898b3498336394c7b01c0e95c479082 313 SUPERFAMILY SSF103481 60 159 6.15E-12 T 28-03-2018 AFA_RS12945 c898b3498336394c7b01c0e95c479082 313 Pfam PF00892 EamA-like transporter family 166 302 1.3E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS12945 c898b3498336394c7b01c0e95c479082 313 Pfam PF00892 EamA-like transporter family 29 156 6.3E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 Gene3D G3DSA:1.20.1600.10 108 229 3.1E-23 T 28-03-2018 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 Gene3D G3DSA:2.40.50.100 53 107 2.4E-7 T 28-03-2018 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 Pfam PF13437 HlyD family secretion protein 194 297 9.9E-6 T 28-03-2018 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 SUPERFAMILY SSF111369 71 312 6.15E-55 T 28-03-2018 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 58 386 5.2E-77 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFA_RS16070 1b6b84ff7c34a62a3f2d86a82073d460 423 Pfam PF13533 Biotin-lipoyl like 84 131 1.5E-15 T 28-03-2018 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 Gene3D G3DSA:1.10.3810.10 39 257 2.7E-43 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 Gene3D G3DSA:3.40.710.10 258 616 8.3E-71 T 28-03-2018 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 Pfam PF00912 Transglycosylase 50 223 1.8E-41 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 31 589 2.0E-175 T 28-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 SUPERFAMILY SSF53955 38 217 3.94E-40 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 SUPERFAMILY SSF56601 255 600 3.6E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 SUPERFAMILY SSF56601 213 227 3.6E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 Pfam PF00905 Penicillin binding protein transpeptidase domain 306 543 1.8E-12 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFA_RS11075 dbf9a0a3192dcfa400ce27d02f02283d 720 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 625 706 4.2E-12 T 28-03-2018 IPR009647 Penicillin-binding, C-terminal AFA_RS12740 49175d9916b24e18b1f425410a9d471f 100 SUPERFAMILY SSF75169 4 99 1.53E-11 T 28-03-2018 IPR027396 DsrEFH-like AFA_RS12740 49175d9916b24e18b1f425410a9d471f 100 Gene3D G3DSA:3.40.1260.10 1 100 3.8E-6 T 28-03-2018 AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 2.7E-42 T 28-03-2018 AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 Gene3D G3DSA:3.40.50.720 3 242 7.1E-58 T 28-03-2018 AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 SUPERFAMILY SSF51735 7 238 2.33E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS00325 94b6e625db70f591323b3dd105b39ff2 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 6.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 Pfam PF12390 Selenocysteine synthase N terminal 11 48 2.0E-6 T 28-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 11 464 1.4E-180 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 Pfam PF03841 L-seryl-tRNA selenium transferase 85 455 3.3E-163 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 Gene3D G3DSA:3.40.640.10 104 349 1.1E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 472 229.575 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 AFA_RS16845 27a62b8685f16354808a9628a55f01f6 472 SUPERFAMILY SSF53383 78 374 1.07E-44 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFA_RS05395 1be4095ccd9e64eda40a393907e09dd1 376 SUPERFAMILY SSF53756 3 365 1.06E-59 T 28-03-2018 AFA_RS05395 1be4095ccd9e64eda40a393907e09dd1 376 Gene3D G3DSA:3.40.50.2000 1 177 6.7E-17 T 28-03-2018 AFA_RS05395 1be4095ccd9e64eda40a393907e09dd1 376 Pfam PF00534 Glycosyl transferases group 1 188 346 3.5E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 AFA_RS05395 1be4095ccd9e64eda40a393907e09dd1 376 Gene3D G3DSA:3.40.50.2000 178 352 4.2E-35 T 28-03-2018 AFA_RS05395 1be4095ccd9e64eda40a393907e09dd1 376 Pfam PF13439 Glycosyltransferase Family 4 14 167 8.7E-22 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 AFA_RS01075 3e61cf9be4cc44c9ddc3cbb4cb59fe10 321 Gene3D G3DSA:3.40.190.10 120 231 1.2E-15 T 28-03-2018 AFA_RS01075 3e61cf9be4cc44c9ddc3cbb4cb59fe10 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 3.7E-77 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS01075 3e61cf9be4cc44c9ddc3cbb4cb59fe10 321 PIRSF PIRSF017082 4 321 5.9E-83 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS01075 3e61cf9be4cc44c9ddc3cbb4cb59fe10 321 SUPERFAMILY SSF53850 112 287 2.75E-15 T 28-03-2018 AFA_RS18470 58a63a230cf526ce5fe51a51898326ca 250 Pfam PF16220 Domain of unknown function (DUF4880) 17 56 1.1E-13 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS18470 58a63a230cf526ce5fe51a51898326ca 250 Pfam PF04773 FecR protein 123 208 5.7E-7 T 28-03-2018 IPR006860 FecR protein AFA_RS13610 d055d790e38c30f9f74b378bede2eaac 122 SUPERFAMILY SSF46626 19 114 1.58E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS13610 d055d790e38c30f9f74b378bede2eaac 122 Gene3D G3DSA:1.10.760.10 13 114 1.5E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS13610 d055d790e38c30f9f74b378bede2eaac 122 Pfam PF00034 Cytochrome c 28 112 3.2E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS04745 e93e4994a21aef5089250f4941ac3ee5 158 Pfam PF06676 Protein of unknown function (DUF1178) 4 150 9.7E-49 T 28-03-2018 IPR009562 Protein of unknown function DUF1178 AFA_RS04745 e93e4994a21aef5089250f4941ac3ee5 158 PIRSF PIRSF032131 3 156 3.0E-40 T 28-03-2018 IPR009562 Protein of unknown function DUF1178 AFA_RS10415 3fb26a8ae09aa335985a053c1d0a1653 298 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 279 3.8E-28 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS10415 3fb26a8ae09aa335985a053c1d0a1653 298 Gene3D G3DSA:1.10.3470.10 2 290 2.5E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS11300 9c4e7518b0da64d600aacc62ae772f20 84 SUPERFAMILY SSF55008 4 67 3.27E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS11300 9c4e7518b0da64d600aacc62ae772f20 84 Pfam PF00403 Heavy-metal-associated domain 15 66 3.7E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFA_RS11300 9c4e7518b0da64d600aacc62ae772f20 84 Gene3D G3DSA:3.30.70.100 2 69 2.7E-13 T 28-03-2018 AFA_RS01475 6a0ad4ee48865916fbf239bd877abf7e 293 Gene3D G3DSA:1.10.3470.10 2 281 6.1E-40 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS01475 6a0ad4ee48865916fbf239bd877abf7e 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 278 2.8E-33 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS02015 25205613a149df318ae996cfb4a97b62 284 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 3 270 9.8E-34 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFA_RS02015 25205613a149df318ae996cfb4a97b62 284 PIRSF PIRSF026649 1 279 1.3E-71 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFA_RS06230 ae73027d69cac5ac2b1e9c9639c99d80 117 Gene3D G3DSA:1.10.760.10 12 106 2.4E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06230 ae73027d69cac5ac2b1e9c9639c99d80 117 SUPERFAMILY SSF46626 37 106 8.58E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS04850 682c6680cd9ae74be77be2b3f1a53b63 127 Gene3D G3DSA:1.20.1300.10 9 127 8.7E-17 T 28-03-2018 AFA_RS04850 682c6680cd9ae74be77be2b3f1a53b63 127 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 118 3.3E-12 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04850 682c6680cd9ae74be77be2b3f1a53b63 127 SUPERFAMILY SSF81343 11 127 1.33E-25 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFA_RS04850 682c6680cd9ae74be77be2b3f1a53b63 127 PIRSF PIRSF000169 8 127 8.0E-37 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 AFA_RS04850 682c6680cd9ae74be77be2b3f1a53b63 127 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 16 125 2.1E-33 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 AFA_RS05660 badc87c2ed72f0ca30eac5c02b8c79ca 288 SMART SM00849 15 206 3.0E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS05660 badc87c2ed72f0ca30eac5c02b8c79ca 288 Gene3D G3DSA:3.60.15.10 1 288 7.6E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS05660 badc87c2ed72f0ca30eac5c02b8c79ca 288 SUPERFAMILY SSF56281 11 286 1.35E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS05660 badc87c2ed72f0ca30eac5c02b8c79ca 288 Pfam PF00753 Metallo-beta-lactamase superfamily 13 206 6.9E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS13185 2c16af9f4cb538f0eb7d4dcda3bb9365 277 SUPERFAMILY SSF51366 7 248 3.58E-83 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AFA_RS13185 2c16af9f4cb538f0eb7d4dcda3bb9365 277 Pfam PF00290 Tryptophan synthase alpha chain 16 258 7.4E-84 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13185 2c16af9f4cb538f0eb7d4dcda3bb9365 277 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 16 248 1.6E-71 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13185 2c16af9f4cb538f0eb7d4dcda3bb9365 277 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 274 33.606 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFA_RS13185 2c16af9f4cb538f0eb7d4dcda3bb9365 277 Gene3D G3DSA:3.20.20.70 5 277 8.4E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS00375 57feeda3970c0d00a19401c46fdc385a 203 Gene3D G3DSA:2.30.110.10 29 197 3.1E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS00375 57feeda3970c0d00a19401c46fdc385a 203 SUPERFAMILY SSF50475 41 195 1.57E-45 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 AFA_RS00375 57feeda3970c0d00a19401c46fdc385a 203 SMART SM00903 50 195 1.1E-50 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS00375 57feeda3970c0d00a19401c46fdc385a 203 Pfam PF01613 Flavin reductase like domain 51 196 1.2E-35 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 AFA_RS16660 c375eabebe66026fe072012d0e733f87 193 SUPERFAMILY SSF52507 5 182 1.57E-61 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS16660 c375eabebe66026fe072012d0e733f87 193 Gene3D G3DSA:3.40.50.1950 5 193 1.1E-51 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS16660 c375eabebe66026fe072012d0e733f87 193 Pfam PF02441 Flavoprotein 6 168 2.1E-24 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFA_RS16660 c375eabebe66026fe072012d0e733f87 193 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 188 36.925 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 AFA_RS16660 c375eabebe66026fe072012d0e733f87 193 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 186 1.6E-73 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 AFA_RS06055 fac22ab0e0b67bd773ec5090740f19ae 518 Pfam PF03781 Sulfatase-modifying factor enzyme 1 121 304 3.6E-29 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFA_RS06055 fac22ab0e0b67bd773ec5090740f19ae 518 Gene3D G3DSA:3.90.1580.10 95 302 3.4E-27 T 28-03-2018 AFA_RS06055 fac22ab0e0b67bd773ec5090740f19ae 518 SUPERFAMILY SSF56436 100 304 5.18E-27 T 28-03-2018 IPR016187 C-type lectin fold AFA_RS17690 4f60692e92d91071072c49abdd80487a 184 Gene3D G3DSA:3.40.630.30 1 181 1.2E-26 T 28-03-2018 AFA_RS17690 4f60692e92d91071072c49abdd80487a 184 SUPERFAMILY SSF55729 2 155 2.98E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase AFA_RS17690 4f60692e92d91071072c49abdd80487a 184 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 3.1E-26 T 28-03-2018 IPR000182 GNAT domain GO:0008080 AFA_RS10245 92098622f7a22f7d066d02a358516c0f 162 Pfam PF02674 Colicin V production protein 4 143 2.4E-34 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 AFA_RS15245 b5f2c9e862a3501ce2b0162c4d308721 364 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 175 5.0E-27 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 9.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 7.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 7.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 7.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 SUPERFAMILY SSF51735 11 260 2.6E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 Gene3D G3DSA:3.40.50.720 4 259 5.9E-64 T 28-03-2018 AFA_RS09440 16551fe87b5169b8c1b4fce3b96e1934 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 259 7.5E-53 T 28-03-2018 AFA_RS03830 35ad1a26611596da98ed9105fbfa4a23 293 Pfam PF01863 Protein of unknown function DUF45 70 284 1.3E-55 T 28-03-2018 IPR002725 Protein of unknown function DUF45 AFA_RS03115 d49866e6ba52a4e6c115d68473389f17 441 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 435 1.3E-150 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS03115 d49866e6ba52a4e6c115d68473389f17 441 PIRSF PIRSF006066 1 441 1.5E-151 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 AFA_RS03115 d49866e6ba52a4e6c115d68473389f17 441 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 429 1.8E-124 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS05915 9e42374c0ab2bd9a129cda66a43dbcb8 91 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 4 70 2.5E-21 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 AFA_RS05915 9e42374c0ab2bd9a129cda66a43dbcb8 91 Pfam PF04347 Flagellar biosynthesis protein, FliO 16 77 1.8E-15 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 AFA_RS12410 743d73afb32fddacf850a0b3cbeb25c5 103 Pfam PF04341 Protein of unknown function, DUF485 13 99 2.8E-21 T 28-03-2018 IPR007436 Protein of unknown function DUF485 AFA_RS06870 3fb3b6d86614c386fd874f44876f2d64 456 Pfam PF06381 Protein of unknown function (DUF1073) 58 400 4.6E-20 T 28-03-2018 IPR024459 Protein of unknown function DUF1073 AFA_RS14660 fabe97fb84dfaea67647acc2408e79e2 468 Pfam PF01554 MatE 255 419 7.0E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS14660 fabe97fb84dfaea67647acc2408e79e2 468 Pfam PF01554 MatE 27 188 1.3E-24 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS14660 fabe97fb84dfaea67647acc2408e79e2 468 PIRSF PIRSF006603 19 463 7.9E-52 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS14660 fabe97fb84dfaea67647acc2408e79e2 468 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 434 1.6E-68 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFA_RS10880 d4cd0726d416d148f991fcd4bae4d64c 288 Pfam PF00482 Type II secretion system (T2SS), protein F 149 275 1.1E-9 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS10880 d4cd0726d416d148f991fcd4bae4d64c 288 Gene3D G3DSA:1.20.1070.10 1 284 0.0011 T 28-03-2018 AFA_RS09900 4ad6280eea43791bbb3fd728f6209b24 465 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 7 462 3.4E-97 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 AFA_RS09900 4ad6280eea43791bbb3fd728f6209b24 465 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 21 461 2.9E-101 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 AFA_RS11705 7f5eb7634d60ffb1fe205aa4fe70c192 1201 Pfam PF05170 AsmA family 9 173 1.4E-12 T 28-03-2018 IPR007844 AsmA AFA_RS11705 7f5eb7634d60ffb1fe205aa4fe70c192 1201 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 298 1185 1.5E-157 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 AFA_RS11705 7f5eb7634d60ffb1fe205aa4fe70c192 1201 Pfam PF13116 Protein of unknown function 408 692 1.7E-40 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 AFA_RS11705 7f5eb7634d60ffb1fe205aa4fe70c192 1201 Pfam PF13502 AsmA-like C-terminal region 935 1179 1.2E-37 T 28-03-2018 IPR032712 AsmA-like, C-terminal AFA_RS00860 29a4605bed7781526439bd180b3ba91a 468 Pfam PF11067 Protein of unknown function (DUF2868) 155 449 8.0E-66 T 28-03-2018 IPR021296 Protein of unknown function DUF2868 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 Pfam PF02049 Flagellar hook-basal body complex protein FliE 25 111 1.0E-27 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 7 111 17.77 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 40 56 8.4E-15 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 96 109 8.4E-15 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 75 91 8.4E-15 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS05965 b67e2286e49dae912dea4f4a43d453c9 111 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 6 109 8.0E-23 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFA_RS15270 5d5a50306e9a0274d2ce27f3c6123cfb 250 SUPERFAMILY SSF52096 2 247 2.41E-66 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS15270 5d5a50306e9a0274d2ce27f3c6123cfb 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 247 5.5E-49 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS15270 5d5a50306e9a0274d2ce27f3c6123cfb 250 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 92 112 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AFA_RS15270 5d5a50306e9a0274d2ce27f3c6123cfb 250 Gene3D G3DSA:3.90.226.10 1 250 2.1E-64 T 28-03-2018 AFA_RS16460 096e7afc79ffa988a32cff86162d0f83 249 Gene3D G3DSA:3.40.50.2020 75 247 1.1E-28 T 28-03-2018 AFA_RS16460 096e7afc79ffa988a32cff86162d0f83 249 SUPERFAMILY SSF53271 67 245 1.84E-25 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like AFA_RS16460 096e7afc79ffa988a32cff86162d0f83 249 Pfam PF00156 Phosphoribosyl transferase domain 149 240 3.4E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 1.1E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 Gene3D G3DSA:3.40.50.2300 1 117 4.6E-32 T 28-03-2018 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 SUPERFAMILY SSF52172 1 172 4.55E-36 T 28-03-2018 IPR011006 CheY-like superfamily AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 SMART SM00448 1 112 6.0E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 SMART SM00862 145 218 5.5E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFA_RS14595 7e103a569a2fd305e8c5a62c52b6e7eb 228 Gene3D G3DSA:1.10.10.10 118 225 5.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS10250 193a47c501f1ab5f567ad5255a9c4176 281 Gene3D G3DSA:3.30.70.1070 200 281 1.0E-19 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS10250 193a47c501f1ab5f567ad5255a9c4176 281 Pfam PF05036 Sporulation related domain 204 278 1.7E-18 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS10250 193a47c501f1ab5f567ad5255a9c4176 281 SUPERFAMILY SSF110997 204 278 2.22E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 AFA_RS16505 41256b3399c385587917d19c9126e27e 335 SUPERFAMILY SSF51735 3 331 1.72E-96 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16505 41256b3399c385587917d19c9126e27e 335 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 332 3.1E-135 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 AFA_RS16505 41256b3399c385587917d19c9126e27e 335 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 326 4.0E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS16505 41256b3399c385587917d19c9126e27e 335 Gene3D G3DSA:3.40.50.720 2 208 6.4E-43 T 28-03-2018 AFA_RS16505 41256b3399c385587917d19c9126e27e 335 Gene3D G3DSA:3.90.25.10 260 335 2.1E-19 T 28-03-2018 AFA_RS16505 41256b3399c385587917d19c9126e27e 335 Gene3D G3DSA:3.90.25.10 209 259 5.3E-11 T 28-03-2018 AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 SUPERFAMILY SSF51735 2 248 4.21E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 Pfam PF00106 short chain dehydrogenase 2 189 4.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 Gene3D G3DSA:3.40.50.720 1 254 2.0E-51 T 28-03-2018 AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 7.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 7.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 7.8E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 180 0.0016 T 28-03-2018 AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS04140 ea2608ddae1a713d16ec2fa728ab3bc4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02975 2de905acf9836c3ab959972f8104a995 234 SUPERFAMILY SSF52540 2 227 2.81E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS02975 2de905acf9836c3ab959972f8104a995 234 Pfam PF00005 ABC transporter 19 162 5.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS02975 2de905acf9836c3ab959972f8104a995 234 SMART SM00382 26 211 4.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS02975 2de905acf9836c3ab959972f8104a995 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFA_RS02975 2de905acf9836c3ab959972f8104a995 234 Gene3D G3DSA:3.40.50.300 1 232 2.1E-53 T 28-03-2018 AFA_RS11755 48b57c2b3649eef9b6d0d625a7c53722 219 SUPERFAMILY SSF46626 22 202 1.18E-25 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11755 48b57c2b3649eef9b6d0d625a7c53722 219 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 191 1.2E-78 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AFA_RS11755 48b57c2b3649eef9b6d0d625a7c53722 219 Gene3D G3DSA:1.10.760.10 42 215 5.5E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS11755 48b57c2b3649eef9b6d0d625a7c53722 219 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 12 183 3.0E-78 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AFA_RS17755 ea22c22f6da265ae07414216753480da 366 SMART SM00849 16 191 3.7E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS17755 ea22c22f6da265ae07414216753480da 366 Gene3D G3DSA:3.60.15.10 1 337 1.1E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS17755 ea22c22f6da265ae07414216753480da 366 SUPERFAMILY SSF56281 5 223 5.24E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS17755 ea22c22f6da265ae07414216753480da 366 Pfam PF12706 Beta-lactamase superfamily domain 41 98 5.6E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase AFA_RS15170 04e139391d4f96bc96cf60dda7e2dce8 87 Gene3D G3DSA:1.20.5.50 1 85 7.4E-4 T 28-03-2018 AFA_RS13735 d8b64a8576841410f8227fdf1adba58c 174 Pfam PF12802 MarR family 53 110 1.6E-10 T 28-03-2018 AFA_RS13735 d8b64a8576841410f8227fdf1adba58c 174 Gene3D G3DSA:1.10.10.10 3 170 3.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13735 d8b64a8576841410f8227fdf1adba58c 174 SUPERFAMILY SSF46785 31 163 5.12E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS13735 d8b64a8576841410f8227fdf1adba58c 174 SMART SM00347 47 147 8.4E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFA_RS17085 8a89bb098e8a2b53dca6922c9b960eb3 176 Pfam PF02417 Chromate transporter 6 168 6.4E-36 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFA_RS02525 c7d5167617c84b59360328cb9f5c536d 389 Gene3D G3DSA:2.130.10.10 254 371 8.7E-20 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS02525 c7d5167617c84b59360328cb9f5c536d 389 Gene3D G3DSA:2.130.10.10 152 253 1.9E-15 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS02525 c7d5167617c84b59360328cb9f5c536d 389 Gene3D G3DSA:2.130.10.10 37 151 3.0E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS02525 c7d5167617c84b59360328cb9f5c536d 389 SUPERFAMILY SSF50969 79 361 1.33E-36 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFA_RS17280 01911587f497c55f80545e3c04b5b118 109 SUPERFAMILY SSF54909 1 102 9.12E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel AFA_RS17280 01911587f497c55f80545e3c04b5b118 109 Pfam PF07978 NIPSNAP 6 102 8.0E-25 T 28-03-2018 IPR012577 NIPSNAP AFA_RS17280 01911587f497c55f80545e3c04b5b118 109 Gene3D G3DSA:3.30.70.100 1 103 6.1E-23 T 28-03-2018 AFA_RS09060 44391185a826eb7a609c3d361a80abb4 204 Pfam PF03942 DTW domain 11 187 3.9E-42 T 28-03-2018 IPR005636 DTW AFA_RS09060 44391185a826eb7a609c3d361a80abb4 204 SMART SM01144 8 192 2.9E-56 T 28-03-2018 IPR005636 DTW AFA_RS09060 44391185a826eb7a609c3d361a80abb4 204 Gene3D G3DSA:3.40.50.1980 40 171 0.0011 T 28-03-2018 AFA_RS06860 200ba9f0a230ee89a4e88d3857fab89f 495 Pfam PF17289 Terminase RNaseH-like domain 329 475 4.7E-13 T 28-03-2018 IPR035421 Terminase, large subunit gp17-like AFA_RS14000 dc01f16107a10328d512be07d79748f0 933 Gene3D G3DSA:3.40.50.1820 81 399 1.4E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14000 dc01f16107a10328d512be07d79748f0 933 SUPERFAMILY SSF53474 62 383 3.82E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14000 dc01f16107a10328d512be07d79748f0 933 Pfam PF11339 Protein of unknown function (DUF3141) 33 604 1.7E-269 T 28-03-2018 IPR024501 Protein of unknown function DUF3141 AFA_RS01985 12a7a44414990b6746c22c378699c349 299 SUPERFAMILY SSF81345 11 268 3.14E-23 T 28-03-2018 IPR029022 ABC transporter, BtuC-like AFA_RS01985 12a7a44414990b6746c22c378699c349 299 Pfam PF00950 ABC 3 transport family 14 272 1.4E-53 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFA_RS01985 12a7a44414990b6746c22c378699c349 299 Gene3D G3DSA:1.10.3470.10 14 279 4.0E-16 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS16980 e7375a4280abf915aa7c4eb44c27bb71 326 Gene3D G3DSA:3.20.20.370 5 298 4.1E-14 T 28-03-2018 AFA_RS16980 e7375a4280abf915aa7c4eb44c27bb71 326 SUPERFAMILY SSF88713 21 285 1.33E-7 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS02295 4cb88c92d69dded36a540adae3f73d5e 233 Pfam PF03741 Integral membrane protein TerC family 14 190 3.2E-46 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFA_RS02295 4cb88c92d69dded36a540adae3f73d5e 233 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.7E-73 T 28-03-2018 IPR022301 Integral membrane protein YjbE AFA_RS04345 93b8b6ad71c6af1e3c3ed8a6c9c3e86e 377 Pfam PF06804 NlpB/DapX lipoprotein 38 370 6.2E-44 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein AFA_RS04345 93b8b6ad71c6af1e3c3ed8a6c9c3e86e 377 Gene3D G3DSA:3.30.530.20 234 365 0.35 T 28-03-2018 IPR023393 START-like domain AFA_RS13605 da9c5955e19dce4f8cb2c936d9e2af93 142 Pfam PF08897 Domain of unknown function (DUF1841) 5 135 1.8E-55 T 28-03-2018 IPR014993 Protein of unknown function DUF1841 AFA_RS06715 f639835323ae6592664cc05e12ca739a 211 Pfam PF09588 YqaJ-like viral recombinase domain 15 153 1.7E-14 T 28-03-2018 IPR019080 YqaJ viral recombinase AFA_RS06715 f639835323ae6592664cc05e12ca739a 211 Gene3D G3DSA:3.90.320.10 1 210 1.2E-42 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 AFA_RS06715 f639835323ae6592664cc05e12ca739a 211 SUPERFAMILY SSF52980 8 203 6.97E-35 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFA_RS03065 59b3bac3e88786b07f21a33e637f2250 199 Pfam PF12804 MobA-like NTP transferase domain 9 166 3.5E-29 T 28-03-2018 IPR025877 MobA-like NTP transferase AFA_RS03065 59b3bac3e88786b07f21a33e637f2250 199 SUPERFAMILY SSF53448 7 193 4.55E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS03065 59b3bac3e88786b07f21a33e637f2250 199 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 196 27.167 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 AFA_RS03065 59b3bac3e88786b07f21a33e637f2250 199 Gene3D G3DSA:3.90.550.10 1 199 7.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS03065 59b3bac3e88786b07f21a33e637f2250 199 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 193 2.6E-58 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 AFA_RS06395 e8fc5f9b419dfa891abb2f598093f7b9 362 Pfam PF00034 Cytochrome c 237 319 9.6E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06395 e8fc5f9b419dfa891abb2f598093f7b9 362 Gene3D G3DSA:1.10.760.10 218 325 1.1E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06395 e8fc5f9b419dfa891abb2f598093f7b9 362 SUPERFAMILY SSF46626 231 325 5.22E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06395 e8fc5f9b419dfa891abb2f598093f7b9 362 Gene3D G3DSA:1.10.760.10 108 213 8.5E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS06395 e8fc5f9b419dfa891abb2f598093f7b9 362 SUPERFAMILY SSF46626 103 216 1.35E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFA_RS07370 51c76ab6208a2fd3efb7ce060151aa08 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 132 4.4E-21 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AFA_RS01900 0f01b72df219e405465ea2ff57bcb9a5 218 PIRSF PIRSF006324 5 212 1.3E-46 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS01900 0f01b72df219e405465ea2ff57bcb9a5 218 Pfam PF01810 LysE type translocator 19 210 9.0E-34 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS10655 cdc4e8ec48b044bda426228e90c80260 301 Gene3D G3DSA:3.30.450.20 168 298 7.2E-12 T 28-03-2018 AFA_RS10655 cdc4e8ec48b044bda426228e90c80260 301 Gene3D G3DSA:3.30.450.20 29 167 2.7E-17 T 28-03-2018 AFA_RS10655 cdc4e8ec48b044bda426228e90c80260 301 Pfam PF08269 Cache domain 76 296 2.7E-14 T 28-03-2018 IPR004010 Double Cache domain 2 AFA_RS00095 e0951e9681e7adb17f732b8eb00cbdfe 279 SMART SM01007 47 229 4.3E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS00095 e0951e9681e7adb17f732b8eb00cbdfe 279 SUPERFAMILY SSF53639 43 247 1.53E-50 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS00095 e0951e9681e7adb17f732b8eb00cbdfe 279 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 47 229 2.9E-39 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS00095 e0951e9681e7adb17f732b8eb00cbdfe 279 Gene3D G3DSA:3.40.225.10 38 274 5.6E-54 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal AFA_RS12810 174ccd8b384c96c41378978509c3eacc 329 Gene3D G3DSA:3.40.190.10 161 320 1.9E-33 T 28-03-2018 AFA_RS12810 174ccd8b384c96c41378978509c3eacc 329 Gene3D G3DSA:3.40.190.10 24 160 6.0E-19 T 28-03-2018 AFA_RS12810 174ccd8b384c96c41378978509c3eacc 329 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 32 308 1.8E-62 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 AFA_RS12810 174ccd8b384c96c41378978509c3eacc 329 SUPERFAMILY SSF53850 29 323 2.24E-79 T 28-03-2018 AFA_RS07195 47fc877b2175880cafca418b5b00d878 109 Pfam PF13031 Protein of unknown function (DUF3892) 30 105 4.3E-8 T 28-03-2018 IPR024997 Protein of unknown function DUF3892 AFA_RS00770 11f373d37159d7d5ac12ec3ebe50ea48 212 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 196 3.4E-62 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFA_RS00770 11f373d37159d7d5ac12ec3ebe50ea48 212 Pfam PF00694 Aconitase C-terminal domain 5 133 7.2E-29 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AFA_RS00770 11f373d37159d7d5ac12ec3ebe50ea48 212 Gene3D G3DSA:3.20.19.10 1 184 2.6E-42 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS00770 11f373d37159d7d5ac12ec3ebe50ea48 212 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 210 35.553 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFA_RS00770 11f373d37159d7d5ac12ec3ebe50ea48 212 SUPERFAMILY SSF52016 4 205 3.14E-55 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AFA_RS00070 cf5ceb001c3aca4135da9a0cfafd7563 197 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 31 161 1.0E-23 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS08700 fecb855f32b3765911682aa4b9283769 95 Pfam PF04380 Membrane fusogenic activity 5 75 9.3E-23 T 28-03-2018 IPR007475 Membrane fusogenic activity AFA_RS10930 c396f8df89135d2e6135ba0c0f8901c3 329 Pfam PF04773 FecR protein 120 212 4.7E-22 T 28-03-2018 IPR006860 FecR protein AFA_RS10930 c396f8df89135d2e6135ba0c0f8901c3 329 PIRSF PIRSF018266 5 329 7.7E-81 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS10930 c396f8df89135d2e6135ba0c0f8901c3 329 Pfam PF16220 Domain of unknown function (DUF4880) 15 57 1.9E-10 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS10930 c396f8df89135d2e6135ba0c0f8901c3 329 Pfam PF16344 Domain of unknown function (DUF4974) 243 309 6.3E-7 T 28-03-2018 IPR032508 Protein FecR, C-terminal AFA_RS06060 859537fb12c46a60e3d2dd22c48fd59d 243 Gene3D G3DSA:1.20.5.320 192 239 0.0026 T 28-03-2018 AFA_RS06060 859537fb12c46a60e3d2dd22c48fd59d 243 Gene3D G3DSA:1.20.5.50 100 191 6.1E-4 T 28-03-2018 AFA_RS11025 9889f4e51c1c0307ae0751b77532001b 298 Pfam PF04381 Putative exonuclease, RdgC 1 296 1.4E-115 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 AFA_RS11025 9889f4e51c1c0307ae0751b77532001b 298 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.146 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 AFA_RS14525 1518cccd99e726318a7c51fb708abd08 368 Pfam PF04143 Sulphur transport 45 358 6.0E-55 T 28-03-2018 IPR007272 Sulphur transport domain AFA_RS05120 614f9c14281f22df8dc80051775ebecc 396 SUPERFAMILY SSF51905 4 151 3.89E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05120 614f9c14281f22df8dc80051775ebecc 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 135 8.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05120 614f9c14281f22df8dc80051775ebecc 396 SUPERFAMILY SSF51905 120 262 1.58E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05120 614f9c14281f22df8dc80051775ebecc 396 Gene3D G3DSA:3.50.50.60 120 262 2.6E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05120 614f9c14281f22df8dc80051775ebecc 396 Gene3D G3DSA:3.50.50.60 2 115 2.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05815 afe09158f28565595725dd0a76382f65 234 SMART SM00858 110 172 1.8E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFA_RS05815 afe09158f28565595725dd0a76382f65 234 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 98 232 9.3E-34 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal AFA_RS05815 afe09158f28565595725dd0a76382f65 234 Gene3D G3DSA:3.90.1210.10 109 175 1.2E-8 T 28-03-2018 AFA_RS05815 afe09158f28565595725dd0a76382f65 234 Pfam PF13144 Chaperone for flagella basal body P-ring formation 36 232 2.1E-42 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal AFA_RS04905 f7d55e2aa873a1a57829f39ac4bedf82 380 SUPERFAMILY SSF52540 67 197 1.07E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS04905 f7d55e2aa873a1a57829f39ac4bedf82 380 Gene3D G3DSA:3.40.50.300 35 371 1.6E-16 T 28-03-2018 AFA_RS04905 f7d55e2aa873a1a57829f39ac4bedf82 380 Pfam PF03969 AFG1-like ATPase 20 372 3.6E-125 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 AFA_RS05220 e0d0a822a0f7addb8288f6cacc044bb0 323 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 8 318 1.8E-87 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter AFA_RS05220 e0d0a822a0f7addb8288f6cacc044bb0 323 PIRSF PIRSF026166 1 323 7.8E-115 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter AFA_RS08510 c6865c2b8f0760a9d92fb82a9a6080a9 90 ProDom PD468738 PHENOL HYDROXYLASE COMPONENT SUBUNIT PHENOLHYDROXYLASE MONOOXYGENASE TOMA0 P0 HYDROCARBONS IRON 9 50 7.0E-11 T 28-03-2018 IPR010353 Phenol hydroxylase subunit KEGG: 00623+1.14.13.7|KEGG: 00627+1.14.13.7|MetaCyc: PWY-5418|MetaCyc: PWY-6197 AFA_RS08510 c6865c2b8f0760a9d92fb82a9a6080a9 90 PIRSF PIRSF000039 1 90 1.5E-29 T 28-03-2018 IPR010353 Phenol hydroxylase subunit KEGG: 00623+1.14.13.7|KEGG: 00627+1.14.13.7|MetaCyc: PWY-5418|MetaCyc: PWY-6197 AFA_RS08510 c6865c2b8f0760a9d92fb82a9a6080a9 90 Pfam PF06099 Phenol hydroxylase subunit 8 58 1.1E-22 T 28-03-2018 IPR010353 Phenol hydroxylase subunit KEGG: 00623+1.14.13.7|KEGG: 00627+1.14.13.7|MetaCyc: PWY-5418|MetaCyc: PWY-6197 AFA_RS15545 f5544d7fa3cd2ab6d19aa199980aa3bf 455 Pfam PF01523 Putative modulator of DNA gyrase 37 328 1.8E-57 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFA_RS15545 f5544d7fa3cd2ab6d19aa199980aa3bf 455 SUPERFAMILY SSF111283 17 454 1.28E-120 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFA_RS15545 f5544d7fa3cd2ab6d19aa199980aa3bf 455 Gene3D G3DSA:3.30.2290.10 1 237 4.1E-60 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain AFA_RS15670 d4827dfa27f673bcbb92422e56c6f61a 195 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 191 1.1E-45 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA AFA_RS15670 d4827dfa27f673bcbb92422e56c6f61a 195 Gene3D G3DSA:3.40.50.1820 1 191 5.7E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS15670 d4827dfa27f673bcbb92422e56c6f61a 195 SUPERFAMILY SSF53474 2 190 1.27E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS10500 6045db72383a3063a607e75e40822692 290 Gene3D G3DSA:2.60.40.1590 42 131 2.4E-29 T 28-03-2018 AFA_RS10500 6045db72383a3063a607e75e40822692 290 SUPERFAMILY SSF51261 134 285 2.09E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif AFA_RS10500 6045db72383a3063a607e75e40822692 290 Pfam PF01551 Peptidase family M23 187 281 1.0E-27 T 28-03-2018 IPR016047 Peptidase M23 AFA_RS10500 6045db72383a3063a607e75e40822692 290 Gene3D G3DSA:2.70.70.10 132 290 3.1E-44 T 28-03-2018 AFA_RS02420 f7a15b62ff93eefc4a84c7ce7c7ef8f6 283 Pfam PF01578 Cytochrome C assembly protein 41 274 6.1E-23 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFA_RS18210 dccf713f02df9d02fdcc06d031942aee 363 Gene3D G3DSA:1.10.540.10 7 118 7.3E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFA_RS18210 dccf713f02df9d02fdcc06d031942aee 363 Gene3D G3DSA:2.40.110.10 125 225 3.4E-10 T 28-03-2018 AFA_RS18210 dccf713f02df9d02fdcc06d031942aee 363 SUPERFAMILY SSF56645 21 224 1.69E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AFA_RS05530 d51f82e9c6453f5b75e83497f3d2103b 342 Gene3D G3DSA:3.20.20.140 1 341 5.9E-54 T 28-03-2018 AFA_RS05530 d51f82e9c6453f5b75e83497f3d2103b 342 Pfam PF04909 Amidohydrolase 3 331 1.5E-55 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 AFA_RS05530 d51f82e9c6453f5b75e83497f3d2103b 342 SUPERFAMILY SSF51556 1 335 6.81E-90 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS11410 b2575649005a4a2b7d6cbe662df76853 288 Pfam PF02678 Pirin 17 122 2.5E-30 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFA_RS11410 b2575649005a4a2b7d6cbe662df76853 288 Gene3D G3DSA:2.60.120.10 1 246 7.6E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS11410 b2575649005a4a2b7d6cbe662df76853 288 Pfam PF05726 Pirin C-terminal cupin domain 175 272 2.5E-25 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFA_RS11410 b2575649005a4a2b7d6cbe662df76853 288 PIRSF PIRSF006232 1 281 3.7E-78 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFA_RS11410 b2575649005a4a2b7d6cbe662df76853 288 SUPERFAMILY SSF51182 5 284 7.8E-73 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS12990 fa7c1d08f4f70bd62366eb1ce782385c 363 SUPERFAMILY SSF53807 14 329 1.22E-44 T 28-03-2018 AFA_RS12990 fa7c1d08f4f70bd62366eb1ce782385c 363 Gene3D G3DSA:3.40.50.1980 12 153 6.3E-16 T 28-03-2018 AFA_RS12990 fa7c1d08f4f70bd62366eb1ce782385c 363 Pfam PF01497 Periplasmic binding protein 89 301 7.7E-24 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 AFA_RS12990 fa7c1d08f4f70bd62366eb1ce782385c 363 Gene3D G3DSA:3.40.50.1980 154 333 5.2E-42 T 28-03-2018 AFA_RS16105 00e8d569ebcc5233de9b5b0d70b7d1e8 63 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 6.0E-24 T 28-03-2018 IPR021853 Protein of unknown function DUF3460 AFA_RS06985 16f721231b62b70667a22575cc4a7dfa 160 Pfam PF10721 Protein of unknown function (DUF2514) 10 154 3.8E-13 T 28-03-2018 IPR019659 Protein of unknown function DUF2514 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Pfam PF00501 AMP-binding enzyme 22 434 6.9E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 28-03-2018 IPR020845 AMP-binding, conserved site AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 518 4.6E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Gene3D G3DSA:3.40.50.980 12 185 2.6E-29 T 28-03-2018 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 SUPERFAMILY SSF56801 6 531 1.31E-131 T 28-03-2018 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Gene3D G3DSA:2.30.38.10 341 427 1.3E-17 T 28-03-2018 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Gene3D G3DSA:3.30.300.30 428 533 2.1E-26 T 28-03-2018 AFA_RS11035 2f06c62a6a376dfa6932af487dfe1d6e 535 Gene3D G3DSA:3.40.50.980 186 340 2.2E-36 T 28-03-2018 AFA_RS09585 18f9a388e876ad4bb5a132838c993c5f 136 Pfam PF11190 Protein of unknown function (DUF2976) 42 132 2.9E-15 T 28-03-2018 IPR021356 Integrating conjugative element protein PFL4702 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 Pfam PF02108 Flagellar assembly protein FliH 109 233 1.0E-32 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 68 90 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 216 241 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 148 170 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 91 109 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 171 198 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 130 147 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS05950 f3921a70520861ee9396b6015080fbf6 246 PRINTS PR01003 Flagellar assembly protein FliH signature 199 215 7.6E-15 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 AFA_RS04245 c0fe57615fd5a7fc52114baa5bc7682c 133 Pfam PF07681 DoxX 8 87 2.4E-13 T 28-03-2018 IPR032808 DoxX family AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 132 150 2.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 37 53 2.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 2.4E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 Gene3D G3DSA:1.20.1260.10 6 155 1.3E-47 T 28-03-2018 IPR012347 Ferritin-related AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 Pfam PF00210 Ferritin-like domain 17 155 5.2E-31 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 PIRSF PIRSF005900 1 155 3.7E-44 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 SUPERFAMILY SSF47240 5 155 8.12E-47 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS09360 2a72c133efed3dc774d4bd5febf4dd91 155 ProSitePatterns PS00819 Dps protein family signature 2. 63 77 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 AFA_RS13825 d68a4fbbd06ad35e5cd29190e06554b0 174 SUPERFAMILY SSF109854 8 157 1.83E-31 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes AFA_RS13825 d68a4fbbd06ad35e5cd29190e06554b0 174 Pfam PF05163 DinB family 8 169 6.5E-30 T 28-03-2018 IPR007837 DNA damage-inducible protein DinB AFA_RS13825 d68a4fbbd06ad35e5cd29190e06554b0 174 Gene3D G3DSA:1.20.120.450 1 174 1.9E-21 T 28-03-2018 AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 7 667 1.8E-280 T 28-03-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 Gene3D G3DSA:3.40.50.300 97 675 6.4E-20 T 28-03-2018 AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 8 666 6.1E-226 T 28-03-2018 IPR022458 Conjugative coupling factor TraG/TraD AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 SUPERFAMILY SSF52540 151 334 4.43E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 SUPERFAMILY SSF52540 410 660 4.43E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09565 fb453d6538401423465dfdf27b97ee9f 754 Pfam PF12696 TraM recognition site of TraD and TraG 522 647 2.0E-7 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site AFA_RS00880 fe89ccc781be1c20fcefc709d51802d5 199 SUPERFAMILY SSF55144 20 189 7.32E-21 T 28-03-2018 IPR009097 Cyclic phosphodiesterase AFA_RS00880 fe89ccc781be1c20fcefc709d51802d5 199 Gene3D G3DSA:3.90.1140.10 13 193 7.1E-18 T 28-03-2018 AFA_RS00880 fe89ccc781be1c20fcefc709d51802d5 199 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 20 188 8.9E-20 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFA_RS06355 8c62d68bc1ed33d025efb5627a9ff40a 71 Pfam PF10038 Protein of unknown function (DUF2274) 5 69 5.5E-26 T 28-03-2018 IPR018733 Protein of unknown function DUF2274 AFA_RS02930 3f7c4da37ee343512acb5e6ef9bbb377 245 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 16 223 6.0E-54 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFA_RS04705 c444cad9f862b58ad278d5e03d2c0041 126 Pfam PF04241 Protein of unknown function (DUF423) 20 106 3.0E-27 T 28-03-2018 IPR006696 Protein of unknown function DUF423 AFA_RS09870 0a8e0311b042edee594b0fa346de2be9 314 Gene3D G3DSA:3.40.50.300 3 286 2.9E-34 T 28-03-2018 AFA_RS09870 0a8e0311b042edee594b0fa346de2be9 314 SUPERFAMILY SSF52540 6 278 9.09E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS09870 0a8e0311b042edee594b0fa346de2be9 314 Pfam PF13614 AAA domain 6 174 2.5E-19 T 28-03-2018 IPR025669 AAA domain AFA_RS00065 e0ba9f620752166e3eee19703b3a151c 589 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 15 524 1.6E-99 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS16015 5712de26e678d357669aa12431d19a93 186 Pfam PF12915 Protein of unknown function (DUF3833) 25 185 6.4E-73 T 28-03-2018 IPR024409 Protein of unknown function DUF3833 AFA_RS04780 530a960717d3f3c8aa9515460b4af5be 640 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 40 630 5.3E-71 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS08765 8658ae58e88f920bb8c1eb7e0ee903c6 164 SUPERFAMILY SSF46785 3 133 8.98E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS08765 8658ae58e88f920bb8c1eb7e0ee903c6 164 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 131 3.3E-42 T 28-03-2018 IPR014290 SUF system FeS cluster assembly regulator AFA_RS08765 8658ae58e88f920bb8c1eb7e0ee903c6 164 Pfam PF02082 Transcriptional regulator 3 83 9.7E-18 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS08765 8658ae58e88f920bb8c1eb7e0ee903c6 164 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 4 132 7.0E-25 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type AFA_RS08765 8658ae58e88f920bb8c1eb7e0ee903c6 164 Gene3D G3DSA:1.10.10.10 2 139 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 435 1.2E-24 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 Gene3D G3DSA:3.40.50.980 15 98 0.25 T 28-03-2018 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 Pfam PF00501 AMP-binding enzyme 81 292 2.6E-16 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 Gene3D G3DSA:3.40.50.980 99 261 2.5E-22 T 28-03-2018 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 PIRSF PIRSF006444 2 437 1.4E-206 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 Gene3D G3DSA:3.30.300.30 328 436 2.7E-10 T 28-03-2018 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 SUPERFAMILY SSF56801 27 432 2.22E-64 T 28-03-2018 AFA_RS11815 895f6e403399e88a77fa21566bc63e56 437 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 435 5.2E-219 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFA_RS08895 ff0be8b7fa75310145eb9d6ca5395f2a 415 SUPERFAMILY SSF53686 16 402 8.38E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS08895 ff0be8b7fa75310145eb9d6ca5395f2a 415 Gene3D G3DSA:3.40.50.1100 64 196 6.9E-33 T 28-03-2018 AFA_RS08895 ff0be8b7fa75310145eb9d6ca5395f2a 415 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 39 402 1.3E-97 T 28-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 AFA_RS08895 ff0be8b7fa75310145eb9d6ca5395f2a 415 Gene3D G3DSA:3.40.50.1100 197 390 4.2E-32 T 28-03-2018 AFA_RS08895 ff0be8b7fa75310145eb9d6ca5395f2a 415 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 387 2.9E-65 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFA_RS11105 ad020722e385515ed38c5b416b75e750 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 3.6E-26 T 28-03-2018 AFA_RS14020 7aaa6a113be4b686b38090693d4e8794 374 Pfam PF12698 ABC-2 family transporter protein 25 363 3.0E-31 T 28-03-2018 AFA_RS14020 7aaa6a113be4b686b38090693d4e8794 374 Gene3D G3DSA:3.40.1710.10 40 193 1.9E-21 T 28-03-2018 AFA_RS15485 647ee650182d0563cb7280a5cbd32199 211 SUPERFAMILY SSF49777 1 201 2.22E-40 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein AFA_RS15485 647ee650182d0563cb7280a5cbd32199 211 Gene3D G3DSA:3.90.280.10 1 204 1.5E-47 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein AFA_RS15485 647ee650182d0563cb7280a5cbd32199 211 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 33 201 8.8E-29 T 28-03-2018 IPR005247 YbhB/YbcL AFA_RS15485 647ee650182d0563cb7280a5cbd32199 211 Pfam PF01161 Phosphatidylethanolamine-binding protein 32 201 4.7E-39 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein AFA_RS01870 2f078f4db531e41ef10fb77f7bd45db5 291 PIRSF PIRSF000846 1 291 3.1E-66 T 28-03-2018 IPR009163 ATP adenylyltransferase GO:0003877|GO:0005524|GO:0009117 KEGG: 00230+2.7.7.53|KEGG: 00920+2.7.7.5|MetaCyc: PWY-5279 AFA_RS01870 2f078f4db531e41ef10fb77f7bd45db5 291 SUPERFAMILY SSF54197 39 153 9.18E-13 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 AFA_RS01870 2f078f4db531e41ef10fb77f7bd45db5 291 Pfam PF09830 ATP adenylyltransferase 228 287 2.5E-15 T 28-03-2018 IPR019200 ATP adenylyltransferase, C-terminal GO:0003877 KEGG: 00230+2.7.7.53|KEGG: 00920+2.7.7.5|MetaCyc: PWY-5279 AFA_RS07105 6bb268474d55d094aad9b75350afed32 195 Pfam PF06805 Bacteriophage lambda tail assembly protein I 7 89 4.9E-10 T 28-03-2018 IPR010654 Bacteriophage lambda tail assembly I AFA_RS16525 dc0acc4ddefcf2039dd14a8fe76613f7 243 SMART SM00382 31 210 4.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain AFA_RS16525 dc0acc4ddefcf2039dd14a8fe76613f7 243 Gene3D G3DSA:3.40.50.300 1 219 1.1E-56 T 28-03-2018 AFA_RS16525 dc0acc4ddefcf2039dd14a8fe76613f7 243 Pfam PF00005 ABC transporter 23 160 5.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS16525 dc0acc4ddefcf2039dd14a8fe76613f7 243 SUPERFAMILY SSF52540 4 235 6.04E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS11765 0d5620ac0a36448641e5cea45b7d77bd 61 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 4 49 9.1E-15 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type AFA_RS11765 0d5620ac0a36448641e5cea45b7d77bd 61 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 5 46 4.3E-15 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type AFA_RS15505 242587eb9a2076b80c185592ed73206c 233 Pfam PF10053 Uncharacterized conserved protein (DUF2290) 49 213 3.3E-15 T 28-03-2018 IPR018742 Protein of unknown function DUF2290 AFA_RS06525 47dd735583113c8dae955b3e2baf7e13 393 Pfam PF13458 Periplasmic binding protein 28 361 7.3E-76 T 28-03-2018 IPR028081 Leucine-binding protein domain AFA_RS06525 47dd735583113c8dae955b3e2baf7e13 393 Gene3D G3DSA:3.40.50.2300 190 351 1.1E-20 T 28-03-2018 AFA_RS06525 47dd735583113c8dae955b3e2baf7e13 393 Gene3D G3DSA:3.40.50.2300 13 189 1.2E-25 T 28-03-2018 AFA_RS06525 47dd735583113c8dae955b3e2baf7e13 393 SUPERFAMILY SSF53822 28 385 7.26E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I AFA_RS00545 0640c2583c5e093c406eee34c61b0f72 170 SUPERFAMILY SSF51182 35 153 1.56E-21 T 28-03-2018 IPR011051 RmlC-like cupin domain AFA_RS00545 0640c2583c5e093c406eee34c61b0f72 170 Pfam PF12973 ChrR Cupin-like domain 38 127 6.5E-12 T 28-03-2018 IPR025979 ChrR-like cupin domain AFA_RS00545 0640c2583c5e093c406eee34c61b0f72 170 Gene3D G3DSA:2.60.120.10 30 168 6.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold AFA_RS00575 faeed5bfc1bb72f09103b680e39a16a2 236 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 30 235 3.1E-21 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 AFA_RS00575 faeed5bfc1bb72f09103b680e39a16a2 236 Gene3D G3DSA:3.40.190.10 111 199 1.6E-18 T 28-03-2018 AFA_RS00575 faeed5bfc1bb72f09103b680e39a16a2 236 Pfam PF13531 Bacterial extracellular solute-binding protein 23 235 7.1E-24 T 28-03-2018 AFA_RS00575 faeed5bfc1bb72f09103b680e39a16a2 236 SUPERFAMILY SSF53850 22 235 1.22E-34 T 28-03-2018 AFA_RS00575 faeed5bfc1bb72f09103b680e39a16a2 236 Gene3D G3DSA:3.40.190.10 21 110 1.9E-4 T 28-03-2018 AFA_RS02625 f088b5a8cc9a9dd073ce66e2547c919f 211 Gene3D G3DSA:3.40.30.10 43 209 1.0E-13 T 28-03-2018 AFA_RS02625 f088b5a8cc9a9dd073ce66e2547c919f 211 Pfam PF02630 SCO1/SenC 67 158 2.7E-8 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS02625 f088b5a8cc9a9dd073ce66e2547c919f 211 SUPERFAMILY SSF52833 66 191 6.69E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12260 2639c8822a12df2550e2a9b5ca78d64b 137 Pfam PF03230 Antirestriction protein 47 137 6.3E-30 T 28-03-2018 IPR004914 Antirestriction protein AFA_RS12260 2639c8822a12df2550e2a9b5ca78d64b 137 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 44 137 8.0E-15 T 28-03-2018 IPR004914 Antirestriction protein AFA_RS00045 e59c934916f26653b86831cbe2a4423b 338 PIRSF PIRSF017082 12 337 1.5E-61 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00045 e59c934916f26653b86831cbe2a4423b 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 334 1.2E-57 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00045 e59c934916f26653b86831cbe2a4423b 338 Gene3D G3DSA:3.40.190.10 139 256 2.7E-9 T 28-03-2018 AFA_RS00045 e59c934916f26653b86831cbe2a4423b 338 SUPERFAMILY SSF53850 113 296 1.34E-10 T 28-03-2018 AFA_RS14365 f3ace5daf109a528b6c46b10ac12e152 272 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 24 237 7.8E-17 T 28-03-2018 AFA_RS08295 496cd1ce8545c8b9d8e3a525fdd9200f 204 SUPERFAMILY SSF52540 2 192 2.03E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08295 496cd1ce8545c8b9d8e3a525fdd9200f 204 Pfam PF00005 ABC transporter 34 157 7.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFA_RS08295 496cd1ce8545c8b9d8e3a525fdd9200f 204 Gene3D G3DSA:3.40.50.300 1 200 2.4E-41 T 28-03-2018 AFA_RS08860 a00e1005685c9423a3151be7d9caa096 173 Pfam PF04972 BON domain 103 170 2.1E-11 T 28-03-2018 IPR007055 BON domain AFA_RS04310 f1127f8780e7292c819496d2a17bac37 319 Pfam PF08223 PaaX-like protein C-terminal domain 191 286 1.3E-26 T 28-03-2018 IPR013225 PaaX-like, C-terminal AFA_RS04310 f1127f8780e7292c819496d2a17bac37 319 Pfam PF07848 PaaX-like protein 23 88 2.1E-26 T 28-03-2018 IPR012906 PaaX-like, N-terminal AFA_RS04310 f1127f8780e7292c819496d2a17bac37 319 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 26 309 3.7E-85 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 AFA_RS04310 f1127f8780e7292c819496d2a17bac37 319 Gene3D G3DSA:1.10.10.10 22 105 2.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS04310 f1127f8780e7292c819496d2a17bac37 319 PIRSF PIRSF020623 5 312 2.7E-91 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 AFA_RS15290 b846ad8e2c50ae4345f3e90a51126d8e 383 Pfam PF02515 CoA-transferase family III 7 374 1.9E-128 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 AFA_RS15290 b846ad8e2c50ae4345f3e90a51126d8e 383 SUPERFAMILY SSF89796 5 379 2.62E-133 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS15290 b846ad8e2c50ae4345f3e90a51126d8e 383 Gene3D G3DSA:3.40.50.10540 1 382 1.8E-143 T 28-03-2018 IPR023606 CoA-transferase family III domain AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.9E-22 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.9E-22 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.9E-22 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.9E-22 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 1.9E-22 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 Pfam PF01494 FAD binding domain 5 343 2.0E-28 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 SUPERFAMILY SSF54373 177 276 2.75E-17 T 28-03-2018 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 SUPERFAMILY SSF51905 270 370 1.02E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 SUPERFAMILY SSF51905 6 172 1.02E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS18565 c8f2392b923aee9b7c1ccf683c6885d8 402 Gene3D G3DSA:3.50.50.60 1 393 5.1E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFA_RS05930 b4a0cb5813e3836ea748a0b11731bf68 173 Pfam PF03748 Flagellar basal body-associated protein FliL 74 173 1.0E-19 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 AFA_RS00030 35edc9c5d17fe297a672bc7a09186ff6 335 PIRSF PIRSF017082 4 334 3.1E-65 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00030 35edc9c5d17fe297a672bc7a09186ff6 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 331 4.9E-64 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS00030 35edc9c5d17fe297a672bc7a09186ff6 335 Gene3D G3DSA:3.40.190.10 146 304 4.9E-10 T 28-03-2018 AFA_RS00030 35edc9c5d17fe297a672bc7a09186ff6 335 SUPERFAMILY SSF53850 123 298 1.52E-10 T 28-03-2018 AFA_RS06410 f11d61c03f10be4cbb470b63b34af715 328 Pfam PF04773 FecR protein 121 210 1.2E-22 T 28-03-2018 IPR006860 FecR protein AFA_RS06410 f11d61c03f10be4cbb470b63b34af715 328 PIRSF PIRSF018266 6 328 1.7E-83 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AFA_RS06410 f11d61c03f10be4cbb470b63b34af715 328 Pfam PF16344 Domain of unknown function (DUF4974) 228 318 1.1E-8 T 28-03-2018 IPR032508 Protein FecR, C-terminal AFA_RS06410 f11d61c03f10be4cbb470b63b34af715 328 Pfam PF16220 Domain of unknown function (DUF4880) 16 55 7.1E-13 T 28-03-2018 IPR032623 FecR, N-terminal AFA_RS00455 e79aa4af8e9ef0c08cb3ea40b8ea8b37 353 Gene3D G3DSA:3.40.710.10 22 346 6.7E-74 T 28-03-2018 AFA_RS00455 e79aa4af8e9ef0c08cb3ea40b8ea8b37 353 Pfam PF00144 Beta-lactamase 22 338 2.5E-64 T 28-03-2018 IPR001466 Beta-lactamase-related AFA_RS00455 e79aa4af8e9ef0c08cb3ea40b8ea8b37 353 SUPERFAMILY SSF56601 25 335 1.37E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like AFA_RS01890 2b06ef4b6d6444434b994600ae12afa8 565 Pfam PF00474 Sodium:solute symporter family 44 428 9.6E-26 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AFA_RS14620 19bb096fbdc7b18e69c704cc7d63fad3 148 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 139 2.2E-26 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AFA_RS14620 19bb096fbdc7b18e69c704cc7d63fad3 148 TIGRFAM TIGR02801 tolR: protein TolR 16 138 7.6E-39 T 28-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 AFA_RS14940 e06fa11ec1f5891247471591fe1b081c 204 SUPERFAMILY SSF53448 10 198 1.08E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS14940 e06fa11ec1f5891247471591fe1b081c 204 Pfam PF12804 MobA-like NTP transferase domain 12 173 1.0E-32 T 28-03-2018 IPR025877 MobA-like NTP transferase AFA_RS14940 e06fa11ec1f5891247471591fe1b081c 204 Gene3D G3DSA:3.90.550.10 8 194 1.4E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFA_RS15910 6275468667bf838e0f7874c1c168f75d 269 Gene3D G3DSA:3.40.830.10 1 266 1.6E-83 T 28-03-2018 AFA_RS15910 6275468667bf838e0f7874c1c168f75d 269 PIRSF PIRSF006157 1 267 2.7E-88 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 AFA_RS15910 6275468667bf838e0f7874c1c168f75d 269 SUPERFAMILY SSF53213 3 266 1.44E-83 T 28-03-2018 AFA_RS15910 6275468667bf838e0f7874c1c168f75d 269 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 29 266 3.0E-43 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFA_RS11750 c4be44353cd7b33b3e6131eb458f6f00 57 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 5 41 3.5E-7 T 28-03-2018 IPR008621 Cbb3-type cytochrome oxidase component AFA_RS15010 db60f6756de773560b2f53be78487d1c 370 Pfam PF00990 Diguanylate cyclase, GGDEF domain 213 365 4.8E-40 T 28-03-2018 IPR000160 GGDEF domain AFA_RS15010 db60f6756de773560b2f53be78487d1c 370 SMART SM00267 202 369 7.4E-50 T 28-03-2018 IPR000160 GGDEF domain AFA_RS15010 db60f6756de773560b2f53be78487d1c 370 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 210 369 1.0E-43 T 28-03-2018 IPR000160 GGDEF domain AFA_RS15010 db60f6756de773560b2f53be78487d1c 370 SUPERFAMILY SSF55073 218 368 4.71E-40 T 28-03-2018 IPR029787 Nucleotide cyclase AFA_RS15010 db60f6756de773560b2f53be78487d1c 370 Gene3D G3DSA:3.30.70.270 206 370 5.9E-50 T 28-03-2018 AFA_RS14175 0e1ec828ea754c402ec59677bf613590 141 Pfam PF13924 Lipocalin-like domain 10 138 6.5E-28 T 28-03-2018 IPR024311 Lipocalin-like domain AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 Gene3D G3DSA:3.40.47.10 1 166 1.1E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 Pfam PF02803 Thiolase, C-terminal domain 270 392 2.0E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 9.4E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 PIRSF PIRSF000429 1 393 9.6E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 Pfam PF00108 Thiolase, N-terminal domain 4 261 1.4E-87 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 Gene3D G3DSA:3.40.47.10 269 390 8.6E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 Gene3D G3DSA:3.40.47.10 167 268 1.1E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 SUPERFAMILY SSF53901 3 270 1.03E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AFA_RS10435 2d7010a3ee2c6c3f0bcd21643f4f7323 393 SUPERFAMILY SSF53901 271 392 3.8E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 SUPERFAMILY SSF46785 7 86 4.02E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 SUPERFAMILY SSF53850 93 300 1.99E-38 T 28-03-2018 AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 Gene3D G3DSA:1.10.10.10 3 93 4.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 9.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 Gene3D G3DSA:3.40.190.10 184 274 9.2E-14 T 28-03-2018 AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 Gene3D G3DSA:3.40.190.10 96 183 1.2E-15 T 28-03-2018 AFA_RS11455 6428e6b06e35e9952cf40cd29b48ce9f 313 Pfam PF03466 LysR substrate binding domain 97 301 1.8E-22 T 28-03-2018 IPR005119 LysR, substrate-binding AFA_RS08585 6159dc8a94278dd2320a2d91c2077588 206 Pfam PF01810 LysE type translocator 15 202 1.2E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS08585 6159dc8a94278dd2320a2d91c2077588 206 PIRSF PIRSF006324 1 205 3.4E-51 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS16010 66b6e9b0cd355ba61a1ae05ca9b4aedf 431 Gene3D G3DSA:1.20.1250.20 217 426 7.9E-9 T 28-03-2018 AFA_RS16010 66b6e9b0cd355ba61a1ae05ca9b4aedf 431 SUPERFAMILY SSF103473 14 420 2.09E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS16010 66b6e9b0cd355ba61a1ae05ca9b4aedf 431 Pfam PF13347 MFS/sugar transport protein 19 420 1.0E-47 T 28-03-2018 AFA_RS16010 66b6e9b0cd355ba61a1ae05ca9b4aedf 431 Gene3D G3DSA:1.20.1250.20 11 206 3.5E-9 T 28-03-2018 AFA_RS17435 6d2ec573d03c812c8f7d2dc524e2b096 114 Pfam PF04972 BON domain 44 112 3.4E-20 T 28-03-2018 IPR007055 BON domain AFA_RS17435 6d2ec573d03c812c8f7d2dc524e2b096 114 SMART SM00749 49 112 5.2E-7 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria AFA_RS09555 077ea18583e017d6c8eea27085f8eeb2 190 Gene3D G3DSA:1.10.530.10 20 189 3.4E-14 T 28-03-2018 AFA_RS09555 077ea18583e017d6c8eea27085f8eeb2 190 SUPERFAMILY SSF53955 24 58 4.79E-16 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS09555 077ea18583e017d6c8eea27085f8eeb2 190 SUPERFAMILY SSF53955 92 167 4.79E-16 T 28-03-2018 IPR023346 Lysozyme-like domain AFA_RS09555 077ea18583e017d6c8eea27085f8eeb2 190 Pfam PF01464 Transglycosylase SLT domain 26 159 1.4E-8 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 AFA_RS05065 e835f665eaa98d7be008d8a1d4fe4b5d 277 Gene3D G3DSA:1.20.1170.10 32 250 4.4E-5 T 28-03-2018 AFA_RS17570 5cfe0a9dc5019e245ee0ec73a08e1fa4 214 Gene3D G3DSA:3.40.50.1000 2 210 1.8E-13 T 28-03-2018 IPR023214 HAD-like domain AFA_RS17570 5cfe0a9dc5019e245ee0ec73a08e1fa4 214 SUPERFAMILY SSF56784 7 196 3.72E-16 T 28-03-2018 IPR023214 HAD-like domain AFA_RS03875 7e02a5d681ca394f26243731258076cc 400 SUPERFAMILY SSF103473 16 390 3.14E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain AFA_RS03875 7e02a5d681ca394f26243731258076cc 400 Gene3D G3DSA:1.20.1250.20 2 202 7.1E-11 T 28-03-2018 AFA_RS03875 7e02a5d681ca394f26243731258076cc 400 Gene3D G3DSA:1.20.1250.20 206 397 1.1E-16 T 28-03-2018 AFA_RS03875 7e02a5d681ca394f26243731258076cc 400 Pfam PF07690 Major Facilitator Superfamily 219 384 1.5E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFA_RS05675 f00cd24ad82d4b206bddf79d1a4c88a0 136 Pfam PF04143 Sulphur transport 41 131 9.8E-7 T 28-03-2018 IPR007272 Sulphur transport domain AFA_RS05625 aac153f0093c12be52e2186d3bf89a65 380 SUPERFAMILY SSF56935 22 380 2.26E-66 T 28-03-2018 AFA_RS05625 aac153f0093c12be52e2186d3bf89a65 380 PRINTS PR00184 Neisseria sp. porin signature 161 178 6.2E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AFA_RS05625 aac153f0093c12be52e2186d3bf89a65 380 PRINTS PR00184 Neisseria sp. porin signature 61 86 6.2E-7 T 28-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AFA_RS05625 aac153f0093c12be52e2186d3bf89a65 380 Gene3D G3DSA:2.40.160.10 7 380 1.7E-62 T 28-03-2018 AFA_RS05625 aac153f0093c12be52e2186d3bf89a65 380 Pfam PF13609 Gram-negative porin 7 360 9.0E-48 T 28-03-2018 AFA_RS09680 4f99b0ba47f46a2c33eb00309d0f6db2 72 Pfam PF11455 Protein of unknown function (DUF3018) 6 70 1.5E-29 T 28-03-2018 IPR021558 Protein of unknown function DUF3018 AFA_RS08270 210387e320167f9b8c516d48e5fe1f46 387 TIGRFAM TIGR00843 benE: benzoate transporter 7 382 7.5E-134 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS08270 210387e320167f9b8c516d48e5fe1f46 387 Pfam PF03594 Benzoate membrane transport protein 8 380 9.3E-140 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.3E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 190 7.8E-5 T 28-03-2018 AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 Gene3D G3DSA:3.40.50.720 2 42 1.0E-11 T 28-03-2018 AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 Gene3D G3DSA:3.40.50.720 43 249 2.0E-58 T 28-03-2018 AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 5.5E-63 T 28-03-2018 AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.6E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFA_RS02935 9fd62e82750aaa031d9a088190f17ea2 249 SUPERFAMILY SSF51735 5 245 7.13E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS14645 89b11a7b8b7928cc5c39f6bc1ec88891 268 SUPERFAMILY SSF53474 7 267 8.37E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14645 89b11a7b8b7928cc5c39f6bc1ec88891 268 Gene3D G3DSA:3.40.50.1820 9 268 3.5E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14645 89b11a7b8b7928cc5c39f6bc1ec88891 268 Pfam PF12697 Alpha/beta hydrolase family 31 260 1.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS12815 1c4d79fa1e67495c71f37fd4f3a7b381 412 PIRSF PIRSF003085 2 408 2.7E-129 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFA_RS12815 1c4d79fa1e67495c71f37fd4f3a7b381 412 SUPERFAMILY SSF53335 115 384 2.48E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS12815 1c4d79fa1e67495c71f37fd4f3a7b381 412 Gene3D G3DSA:3.40.50.150 101 385 6.3E-59 T 28-03-2018 AFA_RS12815 1c4d79fa1e67495c71f37fd4f3a7b381 412 Gene3D G3DSA:3.30.1050.10 3 74 0.0034 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS12815 1c4d79fa1e67495c71f37fd4f3a7b381 412 Pfam PF02353 Mycolic acid cyclopropane synthetase 103 381 1.7E-94 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS05375 cc4483ec7ea2a82776ce9c171596f9bf 280 Pfam PF01522 Polysaccharide deacetylase 56 219 3.4E-34 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFA_RS05375 cc4483ec7ea2a82776ce9c171596f9bf 280 Gene3D G3DSA:3.20.20.370 12 278 1.8E-46 T 28-03-2018 AFA_RS05375 cc4483ec7ea2a82776ce9c171596f9bf 280 SUPERFAMILY SSF88713 22 100 7.17E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS05375 cc4483ec7ea2a82776ce9c171596f9bf 280 SUPERFAMILY SSF88713 137 261 7.17E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFA_RS02145 42338299d0073a1025c7abbd8a0951ae 354 Pfam PF01594 AI-2E family transporter 14 344 1.2E-40 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like AFA_RS06490 1aedd2ebf695e01698f4d3a5a3646db2 639 Pfam PF04632 Fusaric acid resistance protein family 15 616 3.6E-66 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 AFA_RS02965 65f855b19f9bbe8f7581fc7d8e11d6fe 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 293 2.4E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 AFA_RS02965 65f855b19f9bbe8f7581fc7d8e11d6fe 320 Gene3D G3DSA:1.10.3470.10 20 305 1.2E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 Pfam PF00108 Thiolase, N-terminal domain 4 259 5.7E-76 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 PIRSF PIRSF000429 1 380 1.1E-115 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 379 3.5E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 Gene3D G3DSA:3.40.47.10 268 380 9.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 SUPERFAMILY SSF53901 3 266 2.47E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 SUPERFAMILY SSF53901 268 379 4.44E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 Gene3D G3DSA:3.40.47.10 1 267 1.8E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 Pfam PF02803 Thiolase, C-terminal domain 267 379 4.4E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AFA_RS10430 5a57a3d00f1ce619022f5a6bcd63c873 380 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AFA_RS02755 8dea6b3b68ac450a518223197698253a 228 Gene3D G3DSA:1.20.144.10 7 227 7.2E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFA_RS02755 8dea6b3b68ac450a518223197698253a 228 SUPERFAMILY SSF48317 5 224 2.18E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFA_RS02755 8dea6b3b68ac450a518223197698253a 228 Pfam PF01569 PAP2 superfamily 90 220 1.2E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFA_RS10185 a93b22144d90b3aec10b0ab5ed37d2a8 284 Pfam PF01148 Cytidylyltransferase family 3 277 6.6E-58 T 28-03-2018 AFA_RS10185 a93b22144d90b3aec10b0ab5ed37d2a8 284 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 240 266 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 AFA_RS01945 c085943f7adb7d7a018a725eec278a30 101 Pfam PF11604 Copper binding periplasmic protein CusF 36 101 4.4E-24 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF AFA_RS01595 fc025159c7e7a736433a8ce80fb9d870 280 SUPERFAMILY SSF56752 3 276 1.83E-68 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS01595 fc025159c7e7a736433a8ce80fb9d870 280 Pfam PF01063 Amino-transferase class IV 34 254 3.7E-42 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AFA_RS01595 fc025159c7e7a736433a8ce80fb9d870 280 Gene3D G3DSA:3.30.470.10 3 125 5.5E-23 T 28-03-2018 AFA_RS01595 fc025159c7e7a736433a8ce80fb9d870 280 Gene3D G3DSA:3.20.10.10 126 279 7.5E-34 T 28-03-2018 AFA_RS17010 b54dc609b6501fbf75e2be9910dc6896 905 Gene3D G3DSA:3.40.50.150 694 895 9.9E-6 T 28-03-2018 AFA_RS09100 2967c8c7cfa867646fccde36d25fd7ab 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 221 2.4E-19 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AFA_RS09100 2967c8c7cfa867646fccde36d25fd7ab 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 187 204 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site AFA_RS02710 f1da0a85709774e7cc7c6c2ef9a0092a 374 Pfam PF00953 Glycosyl transferase family 4 79 234 2.9E-28 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 AFA_RS00225 4e4324bc531fa1c628032130a5784c4d 331 Pfam PF06189 5'-nucleotidase 38 307 3.0E-107 T 28-03-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 AFA_RS00225 4e4324bc531fa1c628032130a5784c4d 331 Gene3D G3DSA:3.40.50.1000 155 299 2.8E-18 T 28-03-2018 IPR023214 HAD-like domain AFA_RS06875 e6536d6b4e2a323ba30f64e3319de1b7 309 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 164 274 1.8E-13 T 28-03-2018 IPR006528 Phage head morphogenesis domain AFA_RS06875 e6536d6b4e2a323ba30f64e3319de1b7 309 Pfam PF04233 Phage Mu protein F like protein 163 271 5.7E-15 T 28-03-2018 IPR006528 Phage head morphogenesis domain AFA_RS06160 75b9294fe3011e5447333aacd5dd0a36 366 PIRSF PIRSF039026 2 349 5.7E-88 T 28-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AFA_RS06160 75b9294fe3011e5447333aacd5dd0a36 366 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 313 3.6E-41 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS06160 75b9294fe3011e5447333aacd5dd0a36 366 Gene3D G3DSA:3.40.190.10 154 316 0.0089 T 28-03-2018 AFA_RS03020 5a27d4a5dc8f0a457b2d2152789c787b 113 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 7 107 4.8E-30 T 28-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 AFA_RS03020 5a27d4a5dc8f0a457b2d2152789c787b 113 Pfam PF04273 Putative phosphatase (DUF442) 7 107 3.8E-30 T 28-03-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 AFA_RS03020 5a27d4a5dc8f0a457b2d2152789c787b 113 Gene3D G3DSA:3.90.190.10 2 110 3.6E-5 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like AFA_RS12400 b36053185136ec08935c0d516be36244 167 Gene3D G3DSA:3.40.50.450 1 166 4.3E-31 T 28-03-2018 AFA_RS12400 b36053185136ec08935c0d516be36244 167 SUPERFAMILY SSF52309 1 153 8.7E-40 T 28-03-2018 AFA_RS12400 b36053185136ec08935c0d516be36244 167 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 140 1.7E-38 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 AFA_RS10380 316acdcc0e5d3966db6c94303f8fe657 276 Gene3D G3DSA:3.40.50.1820 5 276 2.0E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS10380 316acdcc0e5d3966db6c94303f8fe657 276 Pfam PF00561 alpha/beta hydrolase fold 31 256 5.6E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS10380 316acdcc0e5d3966db6c94303f8fe657 276 SUPERFAMILY SSF53474 8 273 6.89E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS06670 218d0895cb323d7f1a9bcf15a01069ef 78 Gene3D G3DSA:1.10.10.10 7 72 2.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS15865 197a5080e20e9c18ae932da306a91a25 193 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 37 174 6.7E-21 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFA_RS15865 197a5080e20e9c18ae932da306a91a25 193 Pfam PF04093 rod shape-determining protein MreD 34 173 2.5E-16 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFA_RS07590 4b12a3bcb64e22e3c52dd1470a6a09f7 268 Pfam PF01925 Sulfite exporter TauE/SafE 6 264 1.3E-38 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS00835 3898f17fd6442a1587cb180f8c40ae67 207 PIRSF PIRSF006324 1 207 2.8E-50 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS00835 3898f17fd6442a1587cb180f8c40ae67 207 Pfam PF01810 LysE type translocator 16 203 6.9E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS10750 69018895ace475425ecec33932f916e7 334 PIRSF PIRSF026166 1 334 4.9E-127 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter AFA_RS10750 69018895ace475425ecec33932f916e7 334 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 10 319 4.8E-93 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter AFA_RS09780 07fb325c220b5e68b7c13a0b6d6b757f 102 Gene3D G3DSA:1.10.287.540 46 80 0.0028 T 28-03-2018 AFA_RS08450 c21b33e711edd0b134736edce4b61074 134 SUPERFAMILY SSF55298 5 133 3.3E-24 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS08450 c21b33e711edd0b134736edce4b61074 134 Pfam PF01042 Endoribonuclease L-PSP 19 132 2.4E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family AFA_RS08450 c21b33e711edd0b134736edce4b61074 134 Gene3D G3DSA:3.30.1330.40 2 134 3.3E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AFA_RS13665 76b2faeef3af88a24795264a29021163 307 Pfam PF00482 Type II secretion system (T2SS), protein F 140 266 1.4E-15 T 28-03-2018 IPR018076 Type II secretion system F domain AFA_RS06780 e3476e09a8971b0c09063b9188d49a71 297 Gene3D G3DSA:3.30.565.10 99 297 1.1E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS06780 e3476e09a8971b0c09063b9188d49a71 297 SUPERFAMILY SSF55874 103 238 6.69E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain AFA_RS12145 55cf79d065f2e87e31f1cfef7f4f44f5 118 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 22 99 5.2E-18 T 28-03-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB AFA_RS08410 50a5b9f54d34821453d9385f993038cd 138 Pfam PF03692 Putative zinc- or iron-chelating domain 15 100 4.8E-8 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFA_RS11855 e9f6d1e71f3fe1dd0d0f1b1625197792 330 SUPERFAMILY SSF47240 46 290 2.23E-84 T 28-03-2018 IPR009078 Ferritin-like superfamily AFA_RS11855 e9f6d1e71f3fe1dd0d0f1b1625197792 330 Pfam PF05138 Phenylacetic acid catabolic protein 36 311 1.5E-104 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 AFA_RS11855 e9f6d1e71f3fe1dd0d0f1b1625197792 330 Gene3D G3DSA:1.10.620.20 16 315 2.0E-83 T 28-03-2018 AFA_RS11855 e9f6d1e71f3fe1dd0d0f1b1625197792 330 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 26 315 1.9E-164 T 28-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 AFA_RS17815 90fa3a885ea6c47807bba14824d0ff9a 244 SMART SM01236 78 181 7.2E-26 T 28-03-2018 AFA_RS17815 90fa3a885ea6c47807bba14824d0ff9a 244 SUPERFAMILY SSF48613 9 226 1.28E-48 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS17815 90fa3a885ea6c47807bba14824d0ff9a 244 Pfam PF14518 Iron-containing redox enzyme 44 211 7.5E-35 T 28-03-2018 IPR028201 PqqC-like protein AFA_RS17815 90fa3a885ea6c47807bba14824d0ff9a 244 Gene3D G3DSA:1.20.910.10 1 243 4.4E-42 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFA_RS07000 c188ea5eefd19ebab4e725256a8f2de7 227 SUPERFAMILY SSF143081 6 219 2.22E-53 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) AFA_RS07000 c188ea5eefd19ebab4e725256a8f2de7 227 Gene3D G3DSA:3.90.1680.10 1 224 1.5E-51 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) AFA_RS07000 c188ea5eefd19ebab4e725256a8f2de7 227 Pfam PF02586 SOS response associated peptidase (SRAP) 5 214 4.5E-43 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) AFA_RS10015 51a071c75ada5568b420213970366821 189 SUPERFAMILY SSF81342 10 181 6.2E-37 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFA_RS10015 51a071c75ada5568b420213970366821 189 Pfam PF01292 Prokaryotic cytochrome b561 12 181 7.0E-30 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFA_RS10015 51a071c75ada5568b420213970366821 189 Gene3D G3DSA:1.20.950.20 8 188 6.8E-36 T 28-03-2018 AFA_RS16805 cdbe500de711660889237c74bfd88819 282 SUPERFAMILY SSF53850 13 265 1.33E-19 T 28-03-2018 AFA_RS16805 cdbe500de711660889237c74bfd88819 282 PIRSF PIRSF027386 1 282 1.2E-64 T 28-03-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type AFA_RS16805 cdbe500de711660889237c74bfd88819 282 Pfam PF02621 Menaquinone biosynthesis 22 223 2.5E-6 T 28-03-2018 IPR003773 Menaquinone biosynthesis enzyme AFA_RS16805 cdbe500de711660889237c74bfd88819 282 Gene3D G3DSA:3.40.190.10 79 267 2.9E-11 T 28-03-2018 AFA_RS17260 e83fcd3cb16bbcea73df6ae395968bc0 1955 SUPERFAMILY SSF52540 1545 1809 3.76E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17260 e83fcd3cb16bbcea73df6ae395968bc0 1955 Gene3D G3DSA:3.40.50.300 1540 1722 2.6E-5 T 28-03-2018 AFA_RS10970 b6f42fad85fb98f8235d62f57fcb1900 234 Pfam PF03741 Integral membrane protein TerC family 14 190 9.6E-45 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFA_RS10970 b6f42fad85fb98f8235d62f57fcb1900 234 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 191 3.1E-71 T 28-03-2018 IPR022301 Integral membrane protein YjbE AFA_RS06050 142de8a151d70392c5456ce8a65605e3 402 Pfam PF02687 FtsX-like permease family 300 395 3.4E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFA_RS16880 b9505502904c65194c04b0119e971890 752 SUPERFAMILY SSF56935 43 752 8.74E-129 T 28-03-2018 AFA_RS16880 b9505502904c65194c04b0119e971890 752 Pfam PF00593 TonB dependent receptor 318 750 7.7E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16880 b9505502904c65194c04b0119e971890 752 Gene3D G3DSA:2.40.170.20 188 752 3.8E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AFA_RS16880 b9505502904c65194c04b0119e971890 752 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 735 752 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site AFA_RS16880 b9505502904c65194c04b0119e971890 752 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 174 8.8E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS16880 b9505502904c65194c04b0119e971890 752 Gene3D G3DSA:2.170.130.10 52 187 1.6E-35 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AFA_RS09695 7b15c1b7b8b2019762857f26479eb679 169 Pfam PF03703 Bacterial PH domain 75 141 3.6E-10 T 28-03-2018 IPR005182 Domain of unknown function DUF304 AFA_RS02030 3161a7f30ee356b16a89a12781a07e66 112 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 103 2.3E-33 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV AFA_RS03860 21cbe7b4b43cbde9610851c931794b6e 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AFA_RS03860 21cbe7b4b43cbde9610851c931794b6e 255 SUPERFAMILY SSF52096 1 254 1.07E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS03860 21cbe7b4b43cbde9610851c931794b6e 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 254 2.9E-58 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AFA_RS03860 21cbe7b4b43cbde9610851c931794b6e 255 Gene3D G3DSA:1.10.12.10 205 255 4.4E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal AFA_RS03860 21cbe7b4b43cbde9610851c931794b6e 255 Gene3D G3DSA:3.90.226.10 1 204 8.0E-64 T 28-03-2018 AFA_RS09980 2d746e30ec553ac6dd4599b8121f2758 167 Pfam PF04463 Protein of unknown function (DUF523) 4 149 2.6E-43 T 28-03-2018 IPR007553 Domain of unknown function DUF523 AFA_RS08200 81a03b13b05747e010eb4e3b18eaa467 124 Pfam PF02635 DsrE/DsrF-like family 21 114 7.6E-8 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFA_RS08200 81a03b13b05747e010eb4e3b18eaa467 124 Gene3D G3DSA:3.40.1260.10 3 122 1.4E-18 T 28-03-2018 AFA_RS08200 81a03b13b05747e010eb4e3b18eaa467 124 SUPERFAMILY SSF75169 11 117 5.89E-15 T 28-03-2018 IPR027396 DsrEFH-like AFA_RS01430 f92ca70dee357308aefe56a4c02c4737 465 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 209 406 4.3E-7 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region AFA_RS01430 f92ca70dee357308aefe56a4c02c4737 465 Gene3D G3DSA:2.60.40.230 49 126 0.032 T 28-03-2018 AFA_RS01430 f92ca70dee357308aefe56a4c02c4737 465 SUPERFAMILY SSF51004 211 463 5.49E-37 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain AFA_RS01430 f92ca70dee357308aefe56a4c02c4737 465 Gene3D G3DSA:2.130.10.10 142 461 3.7E-37 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS03790 d046ddba77f6fd9763b2259346f44a4a 235 Gene3D G3DSA:1.20.120.330 53 137 5.6E-5 T 28-03-2018 AFA_RS15150 63980054c9dca0a5f123914028e33a6e 338 Gene3D G3DSA:1.10.3470.10 7 338 1.8E-70 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS15150 63980054c9dca0a5f123914028e33a6e 338 SUPERFAMILY SSF81345 8 333 1.31E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like AFA_RS15150 63980054c9dca0a5f123914028e33a6e 338 Pfam PF01032 FecCD transport family 17 333 1.2E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 AFA_RS11395 69acc11214b246048e134bf448d271ec 74 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 6 69 3.3E-31 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor AFA_RS11395 69acc11214b246048e134bf448d271ec 74 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 16 72 9.0E-23 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor AFA_RS00130 c86d8c4e5cf992fc2af554dd470fd9f5 123 Gene3D G3DSA:3.30.1050.10 10 116 7.6E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS13500 a6f652fe83d874b0e4717efdca80c720 262 Pfam PF03883 Peroxide stress protein YaaA 1 243 1.1E-91 T 28-03-2018 IPR005583 Peroxide stress protein YaaA AFA_RS13500 a6f652fe83d874b0e4717efdca80c720 262 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 36.239 T 28-03-2018 IPR005583 Peroxide stress protein YaaA AFA_RS13420 dc711242f68686a67a125e32b3b68820 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 8.1E-39 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS13420 dc711242f68686a67a125e32b3b68820 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 19.913 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 AFA_RS07890 3562f0da6771ad73f3cd69d80442a213 74 Pfam PF12703 Toxin of toxin-antitoxin type 1 system 1 72 9.7E-34 T 28-03-2018 IPR024640 Toxin-antitoxin type 1 system, toxin component AFA_RS14960 c4eab8b600700800e137223f8de87629 274 Pfam PF00561 alpha/beta hydrolase fold 33 257 2.3E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS14960 c4eab8b600700800e137223f8de87629 274 SUPERFAMILY SSF53474 8 270 2.99E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14960 c4eab8b600700800e137223f8de87629 274 Gene3D G3DSA:3.40.50.1820 8 267 6.7E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS00870 02c670a314114ad56f6ce2b07d0705cf 147 Pfam PF04343 Protein of unknown function, DUF488 8 115 1.8E-16 T 28-03-2018 IPR007438 Protein of unknown function DUF488 AFA_RS01575 bf4b0b64f6f34062a9d2168a4563c3d8 245 Pfam PF04116 Fatty acid hydroxylase superfamily 105 234 7.0E-25 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 AFA_RS11415 f2b013e276948dfd599cd6cfe429593f 215 SUPERFAMILY SSF51197 20 213 2.2E-52 T 28-03-2018 AFA_RS11415 f2b013e276948dfd599cd6cfe429593f 215 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 34 212 1.1E-53 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like AFA_RS11415 f2b013e276948dfd599cd6cfe429593f 215 Gene3D G3DSA:2.60.120.590 15 215 3.4E-46 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like AFA_RS07600 ef496bf70028903f40eacb4e18f51e0a 126 Pfam PF03061 Thioesterase superfamily 30 102 1.2E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFA_RS07600 ef496bf70028903f40eacb4e18f51e0a 126 SUPERFAMILY SSF54637 11 118 1.83E-26 T 28-03-2018 IPR029069 HotDog domain AFA_RS07600 ef496bf70028903f40eacb4e18f51e0a 126 Gene3D G3DSA:3.10.129.10 2 121 1.2E-23 T 28-03-2018 AFA_RS07600 ef496bf70028903f40eacb4e18f51e0a 126 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 11 116 1.2E-17 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFA_RS13375 1708f40de5fb27e263a500bb40a02c44 213 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 2.5E-32 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFA_RS14395 f3ce877a037a95f45bea52bd20758e1c 376 PIRSF PIRSF005211 10 376 9.6E-112 T 28-03-2018 IPR012020 AB hydrolase 4 family AFA_RS14395 f3ce877a037a95f45bea52bd20758e1c 376 SUPERFAMILY SSF53474 43 71 8.39E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14395 f3ce877a037a95f45bea52bd20758e1c 376 SUPERFAMILY SSF53474 104 371 8.39E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS14395 f3ce877a037a95f45bea52bd20758e1c 376 Pfam PF00561 alpha/beta hydrolase fold 114 355 6.5E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS14395 f3ce877a037a95f45bea52bd20758e1c 376 Gene3D G3DSA:3.40.50.1820 97 374 2.1E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09840 9d38149415fc09ab5d5591680bec3673 372 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 107 332 7.2E-49 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 AFA_RS09840 9d38149415fc09ab5d5591680bec3673 372 Pfam PF08900 Domain of unknown function (DUF1845) 106 332 1.7E-54 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 AFA_RS04480 6028418217ee403381b3f86e6f8e6f4c 237 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 3 235 4.2E-76 T 28-03-2018 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 AFA_RS04480 6028418217ee403381b3f86e6f8e6f4c 237 SUPERFAMILY SSF52096 26 210 6.04E-15 T 28-03-2018 IPR029045 ClpP/crotonase-like domain AFA_RS04480 6028418217ee403381b3f86e6f8e6f4c 237 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 6 233 3.3E-64 T 28-03-2018 AFA_RS04480 6028418217ee403381b3f86e6f8e6f4c 237 Gene3D G3DSA:3.90.226.10 23 233 4.6E-12 T 28-03-2018 AFA_RS06030 8c8a307e6f407f5c4e7973291cc64c22 859 PIRSF PIRSF034586 1 677 1.5E-232 T 28-03-2018 IPR017030 Virulence effector, SrfC AFA_RS06030 8c8a307e6f407f5c4e7973291cc64c22 859 PIRSF PIRSF034586 666 857 8.4E-33 T 28-03-2018 IPR017030 Virulence effector, SrfC AFA_RS06030 8c8a307e6f407f5c4e7973291cc64c22 859 Pfam PF10139 Putative bacterial virulence factor 25 670 1.3E-250 T 28-03-2018 IPR017030 Virulence effector, SrfC AFA_RS06030 8c8a307e6f407f5c4e7973291cc64c22 859 Pfam PF10139 Putative bacterial virulence factor 672 850 5.5E-32 T 28-03-2018 IPR017030 Virulence effector, SrfC AFA_RS06030 8c8a307e6f407f5c4e7973291cc64c22 859 Gene3D G3DSA:3.40.50.300 27 435 4.5E-5 T 28-03-2018 AFA_RS10775 c23b4bd364a60c470df3e25c54392fd0 205 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 29 160 2.3E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS08820 e709d25fb10db0dffd5132fa18cf963e 161 Pfam PF10627 Curli assembly protein CsgE 56 160 7.6E-36 T 28-03-2018 IPR018900 Curli assembly protein CsgE AFA_RS12775 6f0e01fa7a5a2523fd2ff47cfec5f255 141 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 2 73 7.7E-9 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFA_RS12775 6f0e01fa7a5a2523fd2ff47cfec5f255 141 Gene3D G3DSA:3.10.50.40 1 141 1.3E-13 T 28-03-2018 AFA_RS12775 6f0e01fa7a5a2523fd2ff47cfec5f255 141 SUPERFAMILY SSF54534 2 140 1.55E-25 T 28-03-2018 AFA_RS12695 f15f84ef5fbe3f1b0dc2129e362deabc 500 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 500 6.8E-228 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal AFA_RS12695 f15f84ef5fbe3f1b0dc2129e362deabc 500 Gene3D G3DSA:3.40.50.300 10 342 3.4E-27 T 28-03-2018 AFA_RS12695 f15f84ef5fbe3f1b0dc2129e362deabc 500 SUPERFAMILY SSF52540 11 369 1.0E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17460 1202534d84e80ef5fdcb20a24a955cca 369 SUPERFAMILY SSF50969 37 94 1.02E-28 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFA_RS17460 1202534d84e80ef5fdcb20a24a955cca 369 SUPERFAMILY SSF50969 131 353 1.02E-28 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFA_RS17460 1202534d84e80ef5fdcb20a24a955cca 369 Gene3D G3DSA:2.130.10.10 256 357 1.3E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS17460 1202534d84e80ef5fdcb20a24a955cca 369 Gene3D G3DSA:2.130.10.10 1 113 5.5E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS17460 1202534d84e80ef5fdcb20a24a955cca 369 Gene3D G3DSA:2.130.10.10 119 255 7.3E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AFA_RS04435 23351b3be4cdcc27466d52672acaa485 343 Gene3D G3DSA:3.40.190.10 141 251 1.5E-10 T 28-03-2018 AFA_RS04435 23351b3be4cdcc27466d52672acaa485 343 SUPERFAMILY SSF53850 129 297 7.6E-8 T 28-03-2018 AFA_RS04435 23351b3be4cdcc27466d52672acaa485 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 339 6.2E-86 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS04435 23351b3be4cdcc27466d52672acaa485 343 PIRSF PIRSF017082 14 343 3.1E-77 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS12160 e6f94e613851b905e8b93fff4c0a4e7a 228 Pfam PF07996 Type IV secretion system proteins 26 210 1.5E-36 T 28-03-2018 IPR014158 Type IV secretion system, VirB5 AFA_RS12160 e6f94e613851b905e8b93fff4c0a4e7a 228 Gene3D G3DSA:1.20.58.430 26 212 1.5E-29 T 28-03-2018 AFA_RS12160 e6f94e613851b905e8b93fff4c0a4e7a 228 SUPERFAMILY SSF101082 26 210 9.02E-37 T 28-03-2018 IPR023220 Type IV secretion system, VirB5-domain AFA_RS14955 b90f023ac713fbb2cf4ea5fd45ea0b61 350 SUPERFAMILY SSF144052 135 340 1.96E-16 T 28-03-2018 AFA_RS08145 bf9d57fc54155243ce4108cfa7115710 325 Pfam PF12833 Helix-turn-helix domain 244 318 1.5E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS08145 bf9d57fc54155243ce4108cfa7115710 325 Gene3D G3DSA:1.10.10.60 274 325 1.1E-6 T 28-03-2018 AFA_RS08145 bf9d57fc54155243ce4108cfa7115710 325 SUPERFAMILY SSF46689 274 319 3.9E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 AFA_RS08145 bf9d57fc54155243ce4108cfa7115710 325 Gene3D G3DSA:1.10.10.60 218 273 6.1E-8 T 28-03-2018 AFA_RS08145 bf9d57fc54155243ce4108cfa7115710 325 SMART SM00342 238 320 3.3E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFA_RS06305 b6a74a6b9a4edddd1559abb78f7c27a6 571 Pfam PF09665 Type II restriction endonuclease (RE_Alw26IDE) 33 525 5.6E-188 T 28-03-2018 IPR014328 Restriction endonuclease, type II, Alw26I/Eco31I/Esp3I AFA_RS06305 b6a74a6b9a4edddd1559abb78f7c27a6 571 Gene3D G3DSA:3.40.1800.10 115 339 3.5E-4 T 28-03-2018 AFA_RS06305 b6a74a6b9a4edddd1559abb78f7c27a6 571 TIGRFAM TIGR02986 restrict_Alw26I: type II restriction endonuclease, Alw26I/Eco31I/Esp3I family 32 467 1.7E-174 T 28-03-2018 IPR014328 Restriction endonuclease, type II, Alw26I/Eco31I/Esp3I AFA_RS18570 4390b17c0cbf5274efec64aca2d4db24 291 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 267 1.2E-43 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 AFA_RS04690 2a9073530ab454104f7a565fd03e5746 104 Pfam PF11720 Peptidase inhibitor I78 family 47 104 1.1E-11 T 28-03-2018 IPR021719 Proteinase inhibitor I78 AFA_RS04690 2a9073530ab454104f7a565fd03e5746 104 Gene3D G3DSA:3.30.10.10 49 102 4.3E-4 T 28-03-2018 AFA_RS09050 99ce6f123eded569aa09cfade0fef277 427 SUPERFAMILY SSF56672 22 164 7.34E-11 T 28-03-2018 AFA_RS16875 605ee559cf8607ee48586afa351c86ff 277 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 1 272 2.4E-74 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 AFA_RS16875 605ee559cf8607ee48586afa351c86ff 277 SUPERFAMILY SSF53850 69 240 7.6E-9 T 28-03-2018 AFA_RS16875 605ee559cf8607ee48586afa351c86ff 277 Gene3D G3DSA:3.40.190.10 108 251 1.5E-9 T 28-03-2018 AFA_RS03145 2e811fc3192850855432978dd56eb179 160 Pfam PF11697 Protein of unknown function (DUF3293) 55 127 1.3E-18 T 28-03-2018 IPR021710 Protein of unknown function DUF3293 AFA_RS16420 62fbe27124792dcb48add17aa87c6ff9 522 Gene3D G3DSA:2.70.70.10 248 522 4.2E-30 T 28-03-2018 AFA_RS16420 62fbe27124792dcb48add17aa87c6ff9 522 Gene3D G3DSA:1.20.120.330 22 125 7.3E-6 T 28-03-2018 AFA_RS16420 62fbe27124792dcb48add17aa87c6ff9 522 SUPERFAMILY SSF51261 393 520 3.03E-40 T 28-03-2018 IPR011055 Duplicated hybrid motif AFA_RS16420 62fbe27124792dcb48add17aa87c6ff9 522 Pfam PF01551 Peptidase family M23 423 516 1.5E-24 T 28-03-2018 IPR016047 Peptidase M23 AFA_RS02725 d742973ff2b7863cde9454def488e29c 453 Pfam PF03023 MviN-like protein 46 441 5.9E-33 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFA_RS03030 78ac531b44e0db3e2c84e3b2ac457257 83 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 6 71 1.9E-23 T 28-03-2018 IPR021074 Formate dehydrogenase, delta subunit AFA_RS02335 7e0eb80e2046de4cdf8bed79a4af25d3 126 SUPERFAMILY SSF55174 2 100 8.6E-27 T 28-03-2018 AFA_RS02335 7e0eb80e2046de4cdf8bed79a4af25d3 126 Gene3D G3DSA:3.10.290.10 1 100 1.9E-24 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS02335 7e0eb80e2046de4cdf8bed79a4af25d3 126 Pfam PF01479 S4 domain 5 50 4.3E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS02335 7e0eb80e2046de4cdf8bed79a4af25d3 126 SMART SM00363 4 62 1.3E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 AFA_RS02335 7e0eb80e2046de4cdf8bed79a4af25d3 126 PIRSF PIRSF016821 1 126 4.6E-44 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 AFA_RS11155 f61b8e10150ef33799c544206254cad4 285 Pfam PF01618 MotA/TolQ/ExbB proton channel family 128 239 3.7E-34 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AFA_RS09990 67b2fc9f9c4346b8957bf24772cac996 149 PIRSF PIRSF007951 13 149 1.8E-42 T 28-03-2018 IPR009413 Hemolysin, aegerolysin type GO:0019836 AFA_RS09990 67b2fc9f9c4346b8957bf24772cac996 149 Pfam PF06355 Aegerolysin 20 148 3.9E-37 T 28-03-2018 IPR009413 Hemolysin, aegerolysin type GO:0019836 AFA_RS12680 131522c482337ed2a05fc0c48751123c 286 SUPERFAMILY SSF103481 185 282 5.89E-13 T 28-03-2018 AFA_RS12680 131522c482337ed2a05fc0c48751123c 286 SUPERFAMILY SSF103481 43 137 4.71E-7 T 28-03-2018 AFA_RS12680 131522c482337ed2a05fc0c48751123c 286 Pfam PF00892 EamA-like transporter family 148 276 1.9E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS12680 131522c482337ed2a05fc0c48751123c 286 Pfam PF00892 EamA-like transporter family 9 136 2.3E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS14080 0737f0abd15e4a3e7dfa3fc37ef461af 317 Gene3D G3DSA:1.10.620.20 58 302 1.6E-4 T 28-03-2018 AFA_RS14080 0737f0abd15e4a3e7dfa3fc37ef461af 317 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 10 289 1.2E-51 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF AFA_RS02315 f66d34de20adbed406bc15a7cd9bb2c6 124 SUPERFAMILY SSF101386 6 123 2.62E-38 T 28-03-2018 AFA_RS02315 f66d34de20adbed406bc15a7cd9bb2c6 124 Gene3D G3DSA:1.10.4010.10 1 123 6.9E-25 T 28-03-2018 AFA_RS02315 f66d34de20adbed406bc15a7cd9bb2c6 124 PIRSF PIRSF029826 2 124 5.2E-48 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AFA_RS02315 f66d34de20adbed406bc15a7cd9bb2c6 124 Pfam PF12643 MazG-like family 43 124 3.4E-16 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AFA_RS13850 8dbbaf08d9993a81f86750fc818f56c5 300 Gene3D G3DSA:3.40.50.1820 37 299 5.4E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13850 8dbbaf08d9993a81f86750fc818f56c5 300 SUPERFAMILY SSF53474 40 295 1.94E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13850 8dbbaf08d9993a81f86750fc818f56c5 300 Pfam PF00756 Putative esterase 59 278 1.1E-14 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFA_RS12555 21681c7607b0431129f2fc09867f629e 270 Pfam PF01925 Sulfite exporter TauE/SafE 10 262 6.9E-50 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS00855 61c8e34125f424790cbdd3271e042f11 164 Pfam PF04536 TPM domain 24 139 4.1E-11 T 28-03-2018 IPR007621 TPM domain AFA_RS17555 ad416ee4260bd65b6b0284bfcd70b323 357 Pfam PF02628 Cytochrome oxidase assembly protein 10 320 1.9E-82 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 AFA_RS08280 39c00e89530e40a0d8a96b6627196384 513 Gene3D G3DSA:3.40.50.300 50 512 2.6E-22 T 28-03-2018 AFA_RS08280 39c00e89530e40a0d8a96b6627196384 513 SUPERFAMILY SSF52540 88 262 8.91E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS08280 39c00e89530e40a0d8a96b6627196384 513 Pfam PF01926 50S ribosome-binding GTPase 97 223 1.2E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS04585 42f86e4ebd095839f4708aaf44e49bfa 307 SUPERFAMILY SSF117892 78 214 8.11E-13 T 28-03-2018 IPR001107 Band 7 domain AFA_RS04585 42f86e4ebd095839f4708aaf44e49bfa 307 SMART SM00244 47 213 6.2E-7 T 28-03-2018 IPR001107 Band 7 domain AFA_RS04585 42f86e4ebd095839f4708aaf44e49bfa 307 Pfam PF01145 SPFH domain / Band 7 family 51 229 1.1E-29 T 28-03-2018 IPR001107 Band 7 domain AFA_RS06285 a2e23dfdf45d3474122982183e051305 94 Pfam PF06067 Domain of unknown function (DUF932) 3 83 5.0E-8 T 28-03-2018 IPR026325 Protein of unknown function DUF932 AFA_RS16925 8f567554a240514210cd4a7ed59a4e99 276 Pfam PF12679 ABC-2 family transporter protein 5 274 1.9E-50 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 264 2.0E-53 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 2.0E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 PRINTS PR01713 Nucleotide sugar epimerase signature 45 61 2.0E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 2.0E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 PRINTS PR01713 Nucleotide sugar epimerase signature 258 273 2.0E-8 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 SUPERFAMILY SSF51735 12 338 3.66E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 Gene3D G3DSA:3.90.25.10 190 340 3.4E-34 T 28-03-2018 AFA_RS02720 8d4e923f46093ab2596bed16ad3a8c3e 341 Gene3D G3DSA:3.40.50.720 13 189 9.2E-32 T 28-03-2018 AFA_RS01720 d662fcf1b973f8fe5b653a8505e087e1 182 Pfam PF02975 Methylamine dehydrogenase, L chain 70 178 5.8E-50 T 28-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 AFA_RS01720 d662fcf1b973f8fe5b653a8505e087e1 182 Gene3D G3DSA:2.60.30.10 61 180 1.3E-56 T 28-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 AFA_RS01720 d662fcf1b973f8fe5b653a8505e087e1 182 PIRSF PIRSF000192 2 181 1.7E-53 T 28-03-2018 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 AFA_RS01720 d662fcf1b973f8fe5b653a8505e087e1 182 SUPERFAMILY SSF57561 68 180 4.19E-54 T 28-03-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 AFA_RS04645 dd068ea344e598cb667a0af052f4115c 478 Gene3D G3DSA:3.40.50.1220 305 478 9.8E-84 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS04645 dd068ea344e598cb667a0af052f4115c 478 PIRSF PIRSF000204 2 478 1.8E-209 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 AFA_RS04645 dd068ea344e598cb667a0af052f4115c 478 SUPERFAMILY SSF52467 306 478 1.01E-74 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain AFA_RS04645 dd068ea344e598cb667a0af052f4115c 478 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 476 4.0E-190 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AFA_RS09765 522942a29ad391f440f3138db558eeb3 371 Gene3D G3DSA:3.40.50.150 4 300 6.3E-20 T 28-03-2018 AFA_RS09765 522942a29ad391f440f3138db558eeb3 371 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 6.1E-8 T 28-03-2018 AFA_RS09765 522942a29ad391f440f3138db558eeb3 371 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 136 160 6.1E-8 T 28-03-2018 AFA_RS09765 522942a29ad391f440f3138db558eeb3 371 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 107 119 6.1E-8 T 28-03-2018 AFA_RS09765 522942a29ad391f440f3138db558eeb3 371 SUPERFAMILY SSF53335 18 200 2.19E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS08460 294f5bd261104c1c37d3a3ae259add34 179 Gene3D G3DSA:2.40.128.20 1 179 5.7E-35 T 28-03-2018 IPR012674 Calycin AFA_RS08460 294f5bd261104c1c37d3a3ae259add34 179 SUPERFAMILY SSF50814 12 178 1.71E-37 T 28-03-2018 IPR012674 Calycin AFA_RS08460 294f5bd261104c1c37d3a3ae259add34 179 PIRSF PIRSF036893 1 179 1.8E-47 T 28-03-2018 IPR022271 Lipocalin, ApoD type AFA_RS08460 294f5bd261104c1c37d3a3ae259add34 179 Pfam PF08212 Lipocalin-like domain 29 177 6.3E-41 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain AFA_RS14555 4f3843fff930713382d78693f782a5bc 134 Gene3D G3DSA:1.20.1170.10 1 133 2.0E-8 T 28-03-2018 AFA_RS16930 45e4721b1352f21371834d462b542545 171 Pfam PF05573 NosL 15 163 1.5E-45 T 28-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL AFA_RS16930 45e4721b1352f21371834d462b542545 171 SUPERFAMILY SSF160387 55 164 1.05E-28 T 28-03-2018 AFA_RS03540 9984d2b629a018768f99cf74e54352bf 178 Pfam PF00857 Isochorismatase family 11 148 1.3E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS03540 9984d2b629a018768f99cf74e54352bf 178 Gene3D G3DSA:3.40.50.850 3 178 1.4E-37 T 28-03-2018 AFA_RS03540 9984d2b629a018768f99cf74e54352bf 178 SUPERFAMILY SSF52499 3 178 2.62E-41 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 SUPERFAMILY SSF54593 1 128 1.88E-38 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 127 1.8E-65 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 Gene3D G3DSA:3.10.180.10 1 131 6.9E-38 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFA_RS03825 9a4b868251c52e7f0de89bd970d1e589 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 6.5E-25 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFA_RS07955 3393f5b513ab0aa9ddf32571a75fd780 321 PIRSF PIRSF031982 1 318 8.5E-91 T 28-03-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL AFA_RS07955 3393f5b513ab0aa9ddf32571a75fd780 321 SUPERFAMILY SSF53474 5 170 9.15E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07955 3393f5b513ab0aa9ddf32571a75fd780 321 SUPERFAMILY SSF53474 200 319 9.15E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07955 3393f5b513ab0aa9ddf32571a75fd780 321 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 71 112 2.4E-5 T 28-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 AFA_RS07955 3393f5b513ab0aa9ddf32571a75fd780 321 Gene3D G3DSA:3.40.50.1820 23 320 4.9E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS00305 07d75db075ab58cf61ebf7444ef39352 160 Gene3D G3DSA:3.10.450.50 4 160 2.8E-32 T 28-03-2018 AFA_RS00305 07d75db075ab58cf61ebf7444ef39352 160 Pfam PF00866 Ring hydroxylating beta subunit 16 149 1.3E-30 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 AFA_RS00305 07d75db075ab58cf61ebf7444ef39352 160 SUPERFAMILY SSF54427 2 160 1.72E-46 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS17100 7bb8041bae246c6e0193e90ad95ad5ea 158 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 147 3.4E-58 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 AFA_RS17100 7bb8041bae246c6e0193e90ad95ad5ea 158 Pfam PF02470 MlaD protein 39 116 2.0E-21 T 28-03-2018 IPR003399 Mce/MlaD AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 Gene3D G3DSA:3.30.70.141 55 139 3.6E-33 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 Gene3D G3DSA:3.30.70.141 1 54 7.4E-16 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.447 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 9.3E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 9.3E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 9.3E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 9.3E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 9.3E-38 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 SUPERFAMILY SSF54919 1 139 1.7E-55 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 SMART SM00562 3 140 4.5E-79 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS11585 4e93e0b0969ab774a855982faffec3f0 141 Pfam PF00334 Nucleoside diphosphate kinase 4 137 6.0E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFA_RS04260 ab3fd45d929c27490931724fa5ffe868 145 Pfam PF05232 Chlorhexidine efflux transporter 3 65 2.6E-15 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter AFA_RS04260 ab3fd45d929c27490931724fa5ffe868 145 Pfam PF05232 Chlorhexidine efflux transporter 71 133 6.4E-21 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter AFA_RS15335 70133f347243f685527b3366a2995eff 715 Pfam PF05506 Domain of unknown function (DUF756) 519 608 8.1E-24 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS15335 70133f347243f685527b3366a2995eff 715 Pfam PF05506 Domain of unknown function (DUF756) 618 698 5.1E-23 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS15335 70133f347243f685527b3366a2995eff 715 Pfam PF04185 Phosphoesterase family 44 446 4.1E-100 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 AFA_RS15335 70133f347243f685527b3366a2995eff 715 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 712 2.4E-263 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 AFA_RS15335 70133f347243f685527b3366a2995eff 715 Gene3D G3DSA:3.40.720.10 122 451 8.8E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AFA_RS09820 b8d5204537a3da5ed3d8a11a235d08c8 1101 ProDom PD144061 ECS5259 GENOME STY4851 YJIT 14 413 1.0E-90 T 28-03-2018 AFA_RS18105 55fe8256fce34afbe337a671f7b3fd5c 59 Gene3D G3DSA:3.40.190.10 7 46 1.8E-5 T 28-03-2018 AFA_RS06380 be0b54d27c5d8d8abd0bc5d57a86c850 531 Gene3D G3DSA:1.20.210.10 81 526 8.5E-57 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS06380 be0b54d27c5d8d8abd0bc5d57a86c850 531 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 84 496 1.9E-74 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS06380 be0b54d27c5d8d8abd0bc5d57a86c850 531 SUPERFAMILY SSF81442 81 520 1.22E-85 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFA_RS00865 60d989743ba4554c09cf1ae4e9a498b1 482 Pfam PF11981 Domain of unknown function (DUF3482) 166 462 1.3E-83 T 28-03-2018 IPR021871 Protein of unknown function DUF3482 AFA_RS00865 60d989743ba4554c09cf1ae4e9a498b1 482 SUPERFAMILY SSF52540 6 73 2.68E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00865 60d989743ba4554c09cf1ae4e9a498b1 482 SUPERFAMILY SSF52540 112 171 2.68E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS00865 60d989743ba4554c09cf1ae4e9a498b1 482 Pfam PF01926 50S ribosome-binding GTPase 8 153 3.1E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 AFA_RS00865 60d989743ba4554c09cf1ae4e9a498b1 482 Gene3D G3DSA:3.40.50.300 2 286 6.9E-25 T 28-03-2018 AFA_RS02415 9e345aa957a94c5c9465de1ba72fee22 83 Gene3D G3DSA:2.30.170.10 45 83 1.4E-5 T 28-03-2018 AFA_RS09020 dae264aa3b3d7d9f72f27401866b59b8 455 Pfam PF02386 Cation transport protein 47 435 2.9E-51 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AFA_RS03245 97667adf015cb0b6fc29263dd3fc425c 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 1.0E-16 T 28-03-2018 IPR003849 Preprotein translocase YajC AFA_RS03245 97667adf015cb0b6fc29263dd3fc425c 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 1.0E-16 T 28-03-2018 IPR003849 Preprotein translocase YajC AFA_RS03245 97667adf015cb0b6fc29263dd3fc425c 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 105 5.5E-25 T 28-03-2018 IPR003849 Preprotein translocase YajC AFA_RS03245 97667adf015cb0b6fc29263dd3fc425c 114 Pfam PF02699 Preprotein translocase subunit 24 103 5.5E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC AFA_RS03245 97667adf015cb0b6fc29263dd3fc425c 114 SMART SM01323 20 106 3.5E-42 T 28-03-2018 IPR003849 Preprotein translocase YajC AFA_RS17695 2d73d6c90d1ad6f1afed2f45b2440189 163 Pfam PF11158 Protein of unknown function (DUF2938) 11 158 1.9E-59 T 28-03-2018 IPR021329 Protein of unknown function DUF2938 AFA_RS08060 716aeffed20e035519c43980afd16abf 181 Pfam PF01292 Prokaryotic cytochrome b561 9 176 1.1E-13 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFA_RS08060 716aeffed20e035519c43980afd16abf 181 SUPERFAMILY SSF81342 8 176 6.59E-14 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFA_RS08060 716aeffed20e035519c43980afd16abf 181 Gene3D G3DSA:1.20.950.20 1 181 3.1E-14 T 28-03-2018 AFA_RS07165 184d3efe8ccf20b9d54a47364f67ed2e 176 Gene3D G3DSA:3.40.50.300 5 164 2.1E-11 T 28-03-2018 AFA_RS07165 184d3efe8ccf20b9d54a47364f67ed2e 176 SUPERFAMILY SSF52540 9 120 8.67E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFA_RS17960 cb4e0baefa7215294e555c61a1208bf6 361 Gene3D G3DSA:3.20.20.30 11 361 4.9E-69 T 28-03-2018 AFA_RS17960 cb4e0baefa7215294e555c61a1208bf6 361 SUPERFAMILY SSF51679 11 360 2.36E-80 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS17960 cb4e0baefa7215294e555c61a1208bf6 361 Pfam PF00296 Luciferase-like monooxygenase 14 331 1.2E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFA_RS16485 a3c93e822834ca0b4caac0f09d1ca58a 194 Pfam PF14334 Domain of unknown function (DUF4390) 33 183 2.2E-51 T 28-03-2018 IPR025500 Protein of unknown function DUF4390 AFA_RS05830 e83986118d7dbe703bb2625d851e3e57 230 Pfam PF13861 FlgD Tudor-like domain 88 227 2.6E-19 T 28-03-2018 IPR025963 FlgD Tudor-like domain AFA_RS05830 e83986118d7dbe703bb2625d851e3e57 230 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 78 6.0E-22 T 28-03-2018 IPR005648 Flagellar hook capping protein AFA_RS05830 e83986118d7dbe703bb2625d851e3e57 230 Pfam PF13860 FlgD Ig-like domain 117 187 3.4E-20 T 28-03-2018 IPR025965 FlgD Ig-like domain AFA_RS06190 730cf85a926480585c097d3c43646c32 339 Pfam PF11804 Protein of unknown function (DUF3325) 10 94 1.7E-21 T 28-03-2018 IPR021762 Protein of unknown function DUF3325 AFA_RS12320 f281585cdf2c98acb04ac297a8b308f6 157 SUPERFAMILY SSF47175 44 146 2.21E-18 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 AFA_RS12320 f281585cdf2c98acb04ac297a8b308f6 157 Gene3D G3DSA:1.20.120.10 36 148 2.7E-13 T 28-03-2018 AFA_RS12320 f281585cdf2c98acb04ac297a8b308f6 157 Pfam PF01322 Cytochrome C' 86 146 6.2E-6 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 AFA_RS02645 ebe3f06b7d86824d29c61659dbad919b 132 SUPERFAMILY SSF143744 4 132 3.01E-35 T 28-03-2018 AFA_RS02645 ebe3f06b7d86824d29c61659dbad919b 132 Pfam PF03928 Haem-degrading 7 129 9.0E-31 T 28-03-2018 IPR005624 Haem-degrading AFA_RS11325 caabb114cd013da3db7df3457add46b3 199 Pfam PF03551 Transcriptional regulator PadR-like family 33 101 3.5E-14 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal AFA_RS11325 caabb114cd013da3db7df3457add46b3 199 Gene3D G3DSA:1.10.10.10 17 107 5.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS11325 caabb114cd013da3db7df3457add46b3 199 SUPERFAMILY SSF46785 23 112 1.53E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS09625 307d4aae4f55496881cc5cfe52a64016 438 Pfam PF06834 TraU protein 27 170 3.6E-12 T 28-03-2018 IPR009649 TraU AFA_RS09625 307d4aae4f55496881cc5cfe52a64016 438 Pfam PF06834 TraU protein 261 428 6.1E-28 T 28-03-2018 IPR009649 TraU AFA_RS16005 cca61bfc91e83b4cc7e7c98c41987e68 189 Gene3D G3DSA:3.50.70.10 27 171 1.2E-14 T 28-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 AFA_RS00890 193dfb91bed0887c4e5bcbd5f526fb84 224 Gene3D G3DSA:3.30.70.100 15 108 3.1E-5 T 28-03-2018 AFA_RS07520 6fa942ac6b6290992459948abc2f6e0a 218 Pfam PF00551 Formyl transferase 9 188 1.5E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS07520 6fa942ac6b6290992459948abc2f6e0a 218 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 9 194 31.018 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFA_RS07520 6fa942ac6b6290992459948abc2f6e0a 218 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 9 198 2.2E-70 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFA_RS07520 6fa942ac6b6290992459948abc2f6e0a 218 Gene3D G3DSA:3.40.50.170 1 209 6.7E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS07520 6fa942ac6b6290992459948abc2f6e0a 218 SUPERFAMILY SSF53328 9 204 6.8E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFA_RS15995 f1b347ce345b6a9a5b06beb04a5c88d0 250 Pfam PF07103 Protein of unknown function (DUF1365) 9 242 5.9E-67 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 AFA_RS06200 087c80c13b38d36e2adb5ae85c46af9a 545 Pfam PF03929 PepSY-associated TM region 2 372 6.2E-64 T 28-03-2018 IPR005625 PepSY-associated TM protein AFA_RS08335 fb5373f091597c798e5435a938ee4e33 387 Pfam PF05940 NnrS protein 17 385 1.2E-83 T 28-03-2018 IPR010266 NnrS AFA_RS16315 0dd6feef386e604ebd31781c70cfb1ff 527 PIRSF PIRSF006446 2 327 1.5E-114 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFA_RS16315 0dd6feef386e604ebd31781c70cfb1ff 527 PIRSF PIRSF006446 354 522 1.6E-35 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFA_RS16315 0dd6feef386e604ebd31781c70cfb1ff 527 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 1.4E-175 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFA_RS16100 98a346557b0f7544b735181c64454c38 280 Gene3D G3DSA:1.10.10.580 196 266 1.8E-13 T 28-03-2018 AFA_RS16100 98a346557b0f7544b735181c64454c38 280 Hamap MF_01805 Segregation and condensation protein A [scpA]. 34 268 20.787 T 28-03-2018 IPR003768 Segregation and condensation protein A AFA_RS16100 98a346557b0f7544b735181c64454c38 280 Pfam PF02616 Segregation and condensation protein ScpA 51 265 2.3E-32 T 28-03-2018 IPR003768 Segregation and condensation protein A AFA_RS00150 2e4b3d3420ec3e55b2b0eb8430a0193f 251 Gene3D G3DSA:3.20.20.70 30 237 2.5E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFA_RS12085 af4dc5bd9d9a09964b51b28b7fefe08d 205 Pfam PF01810 LysE type translocator 16 201 8.3E-39 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS08040 a105737e596b6559fafaed4b14c96524 268 SUPERFAMILY SSF53613 1 265 5.14E-74 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS08040 a105737e596b6559fafaed4b14c96524 268 Gene3D G3DSA:3.40.1190.20 1 268 2.2E-58 T 28-03-2018 IPR029056 Ribokinase-like AFA_RS08040 a105737e596b6559fafaed4b14c96524 268 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 261 1.8E-88 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFA_RS08040 a105737e596b6559fafaed4b14c96524 268 Pfam PF08543 Phosphomethylpyrimidine kinase 12 259 3.8E-86 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFA_RS15075 82ce438842a4bc208095b62332c5427b 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 7 138 4.8E-24 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS00625 dda7c91260680c2039681eaab9c68059 165 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 154 6.8E-28 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS15390 bcecb91f861cb6527892d2bb184dfcbb 205 Pfam PF01810 LysE type translocator 14 200 7.2E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS15390 bcecb91f861cb6527892d2bb184dfcbb 205 PIRSF PIRSF006324 1 203 1.7E-45 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS08810 945b665a56cc30f21f0e860c649b0cbe 321 Gene3D G3DSA:3.40.50.10070 56 217 4.8E-22 T 28-03-2018 AFA_RS08810 945b665a56cc30f21f0e860c649b0cbe 321 Pfam PF03783 Curli production assembly/transport component CsgG 56 267 5.8E-69 T 28-03-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 AFA_RS13890 2764f562c1e839dbe5da4fd988c36a24 96 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 13 95 2.7E-8 T 28-03-2018 IPR009241 Toxin HigB-like AFA_RS13890 2764f562c1e839dbe5da4fd988c36a24 96 PIRSF PIRSF028744 1 96 3.2E-41 T 28-03-2018 IPR014056 Addiction module killer protein, predicted AFA_RS13890 2764f562c1e839dbe5da4fd988c36a24 96 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 3 95 1.8E-40 T 28-03-2018 IPR014056 Addiction module killer protein, predicted AFA_RS06695 77244148189014103cee80b4a9c8d623 397 Gene3D G3DSA:3.40.50.1820 138 392 4.1E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS06695 77244148189014103cee80b4a9c8d623 397 SUPERFAMILY SSF53474 172 282 6.78E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS06170 137ffade0e55e48d9913398c5fdcc896 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 157 1.2E-27 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS11655 d144762716ca78bebed427af632974ba 298 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 203 282 2.9E-21 T 28-03-2018 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal AFA_RS11655 d144762716ca78bebed427af632974ba 298 Pfam PF03524 Conjugal transfer protein 45 121 1.6E-11 T 28-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX AFA_RS01535 d7eb4ebeac89fabbe6b79e583f4d954e 350 SUPERFAMILY SSF81345 15 346 3.01E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like AFA_RS01535 d7eb4ebeac89fabbe6b79e583f4d954e 350 Gene3D G3DSA:1.10.3470.10 16 350 5.6E-73 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like AFA_RS01535 d7eb4ebeac89fabbe6b79e583f4d954e 350 Pfam PF01032 FecCD transport family 32 346 1.7E-83 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 AFA_RS05435 f009adbbe5d7d7a94764dee335e88020 141 Pfam PF04886 PT repeat 36 69 2.9E-8 T 28-03-2018 IPR006970 PT repeat AFA_RS07860 29c3b8dccc538ff093fc9843cd3ebce6 293 Pfam PF06504 Replication protein C (RepC) 5 275 3.9E-142 T 28-03-2018 IPR010522 Replication protein C, bacterial AFA_RS07860 29c3b8dccc538ff093fc9843cd3ebce6 293 Gene3D G3DSA:1.10.10.10 199 270 0.0041 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS03130 da8e06fd5c516d2a0ccfc0262a9b092f 283 SUPERFAMILY SSF103481 184 281 7.32E-8 T 28-03-2018 AFA_RS03130 da8e06fd5c516d2a0ccfc0262a9b092f 283 SUPERFAMILY SSF103481 41 136 1.44E-6 T 28-03-2018 AFA_RS05015 c5f5f889c27b52a09551e8b069407d87 122 Pfam PF10721 Protein of unknown function (DUF2514) 8 118 2.1E-9 T 28-03-2018 IPR019659 Protein of unknown function DUF2514 AFA_RS10140 733377baf0b4f4904005c6952823a647 201 Hamap MF_00052_B Ribonuclease HII [rnhB]. 15 195 37.348 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 AFA_RS10140 733377baf0b4f4904005c6952823a647 201 Pfam PF01351 Ribonuclease HII 17 194 3.8E-40 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain AFA_RS10140 733377baf0b4f4904005c6952823a647 201 SUPERFAMILY SSF53098 12 198 2.28E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS10140 733377baf0b4f4904005c6952823a647 201 Gene3D G3DSA:3.30.420.10 4 201 5.1E-68 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS03930 268eacb958000cbea8e9e7d568b3cc34 216 Pfam PF09335 SNARE associated Golgi protein 46 170 2.5E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein AFA_RS02840 1972da2aa07512cc052b2188d3a8d41e 136 PIRSF PIRSF020555 12 130 3.8E-35 T 28-03-2018 IPR014508 Uncharacterised conserved protein withTPR-like repeats AFA_RS02840 1972da2aa07512cc052b2188d3a8d41e 136 Pfam PF16068 Domain of unknown function (DUF4810) 37 121 1.3E-28 T 28-03-2018 IPR014508 Uncharacterised conserved protein withTPR-like repeats AFA_RS17790 e9d2426935861b90d7186f61583ed962 102 Gene3D G3DSA:3.10.20.30 2 100 1.2E-18 T 28-03-2018 IPR012675 Beta-grasp domain AFA_RS17790 e9d2426935861b90d7186f61583ed962 102 SUPERFAMILY SSF54292 1 102 3.8E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS17790 e9d2426935861b90d7186f61583ed962 102 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 85 3.7E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFA_RS15330 48dce76a5db29c38df8f9be130a57acd 79 Gene3D G3DSA:3.40.190.10 6 70 1.7E-4 T 28-03-2018 AFA_RS09095 342ff1570b803f5828e7dd28db2e28f1 151 Pfam PF06366 Flagellar protein FlhE 57 150 1.3E-7 T 28-03-2018 IPR009420 Flagellar protein FlhE AFA_RS04030 b0cd5547fdfa4a1f2c48dba78a92a321 203 SUPERFAMILY SSF51735 1 202 1.19E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS04030 b0cd5547fdfa4a1f2c48dba78a92a321 203 Gene3D G3DSA:3.40.50.720 1 203 2.9E-26 T 28-03-2018 AFA_RS04030 b0cd5547fdfa4a1f2c48dba78a92a321 203 Pfam PF13460 NAD(P)H-binding 8 192 1.8E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain AFA_RS06790 5c6b99f892e2b01d92a9a43dcba39a19 68 Gene3D G3DSA:1.10.260.40 1 57 8.8E-8 T 28-03-2018 AFA_RS12735 bc00c937728d076c75621a01272946e6 257 Gene3D G3DSA:3.40.30.10 111 254 1.7E-18 T 28-03-2018 AFA_RS12735 bc00c937728d076c75621a01272946e6 257 Pfam PF13098 Thioredoxin-like domain 121 247 8.3E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12735 bc00c937728d076c75621a01272946e6 257 Gene3D G3DSA:3.10.450.70 31 92 9.3E-17 T 28-03-2018 AFA_RS12735 bc00c937728d076c75621a01272946e6 257 SUPERFAMILY SSF52833 95 247 3.65E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold AFA_RS12735 bc00c937728d076c75621a01272946e6 257 SUPERFAMILY SSF54423 27 85 4.84E-15 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AFA_RS12305 d683be6a28378805e1ad4c66b210bbee 990 Pfam PF01526 Tn3 transposase DDE domain 581 968 4.0E-156 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 AFA_RS12305 d683be6a28378805e1ad4c66b210bbee 990 Pfam PF13700 Domain of unknown function (DUF4158) 6 169 1.2E-52 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 AFA_RS10490 91ad8e0d8ea57de3c1555e7a0ad4cc21 114 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 108 1.1E-10 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD AFA_RS13700 5f4cf23aa2bc9078ab6595c8c6fd9118 167 Pfam PF01478 Type IV leader peptidase family 12 121 1.8E-11 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFA_RS09710 564a6697ff3b352065df0ebd72821c99 297 Gene3D G3DSA:1.10.530.10 23 127 6.0E-4 T 28-03-2018 AFA_RS14650 0117706f8fa9a329b9cdaf3e0d61aa06 161 Pfam PF04314 Copper chaperone PCu(A)C 43 148 1.7E-27 T 28-03-2018 IPR007410 Copper chaperone PCuAC AFA_RS14650 0117706f8fa9a329b9cdaf3e0d61aa06 161 SUPERFAMILY SSF110087 40 155 4.32E-30 T 28-03-2018 IPR007410 Copper chaperone PCuAC AFA_RS01855 d1bc207ba12a8e58a02a7a45f695dc44 116 Pfam PF03788 LrgA family 12 104 2.4E-25 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 AFA_RS04700 30a7bbd0fd7ea5f6469ff00bf3c13798 345 Pfam PF00962 Adenosine/AMP deaminase 15 336 1.8E-76 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 AFA_RS04700 30a7bbd0fd7ea5f6469ff00bf3c13798 345 Hamap MF_01962 Adenine deaminase. 11 327 80.768 T 28-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFA_RS04700 30a7bbd0fd7ea5f6469ff00bf3c13798 345 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 338 3.7E-115 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 AFA_RS04700 30a7bbd0fd7ea5f6469ff00bf3c13798 345 Gene3D G3DSA:3.20.20.140 3 341 6.4E-82 T 28-03-2018 AFA_RS04700 30a7bbd0fd7ea5f6469ff00bf3c13798 345 SUPERFAMILY SSF51556 10 341 1.04E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase AFA_RS05510 b5e15b2dddc230a0f385251fbbfee566 282 SUPERFAMILY SSF53213 2 278 1.2E-96 T 28-03-2018 AFA_RS05510 b5e15b2dddc230a0f385251fbbfee566 282 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 272 3.7E-87 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFA_RS05510 b5e15b2dddc230a0f385251fbbfee566 282 Gene3D G3DSA:3.40.830.10 1 282 3.8E-58 T 28-03-2018 AFA_RS07155 ab5d2151f3f389e29f3082dfa69bd672 157 Pfam PF10721 Protein of unknown function (DUF2514) 7 146 3.3E-8 T 28-03-2018 IPR019659 Protein of unknown function DUF2514 AFA_RS07155 ab5d2151f3f389e29f3082dfa69bd672 157 Gene3D G3DSA:1.20.1170.10 5 150 4.9E-5 T 28-03-2018 AFA_RS08215 f9fac622f89eba582aa9613109db388d 65 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 1.2E-24 T 28-03-2018 IPR021309 Protein of unknown function DUF2892 AFA_RS03280 d4b52a21d4c48ffc00cf77403c8a3807 129 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 5 117 2.4E-15 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III AFA_RS00795 49b8ea766e97c5ee0021baca25623ea4 172 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 158 1.6E-28 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS03450 3c739109225139adf00fcf875496587c 271 SUPERFAMILY SSF53474 20 268 2.68E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS03450 3c739109225139adf00fcf875496587c 271 Pfam PF12697 Alpha/beta hydrolase family 37 260 1.4E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 AFA_RS03450 3c739109225139adf00fcf875496587c 271 Gene3D G3DSA:3.40.50.1820 17 271 5.8E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS07550 d18c17d400efa455d5b33442c77303bf 648 SUPERFAMILY SSF56300 155 195 6.53E-7 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07550 d18c17d400efa455d5b33442c77303bf 648 SUPERFAMILY SSF56300 409 536 6.53E-7 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07550 d18c17d400efa455d5b33442c77303bf 648 SUPERFAMILY SSF56300 314 356 6.53E-7 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07550 d18c17d400efa455d5b33442c77303bf 648 Gene3D G3DSA:3.60.21.10 104 634 1.6E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like AFA_RS07550 d18c17d400efa455d5b33442c77303bf 648 Pfam PF09423 PhoD-like phosphatase 310 582 8.3E-7 T 28-03-2018 IPR018946 Alkaline phosphatase D-related AFA_RS15120 ff1bee9d1825164f57963c6cc60060bc 216 Gene3D G3DSA:3.40.50.850 4 215 6.0E-47 T 28-03-2018 AFA_RS15120 ff1bee9d1825164f57963c6cc60060bc 216 SUPERFAMILY SSF52499 26 212 6.8E-54 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS15120 ff1bee9d1825164f57963c6cc60060bc 216 Pfam PF00857 Isochorismatase family 34 209 2.9E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AFA_RS03580 8d681c959fd85bd21e5d5cc45d13efe3 349 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 20 335 2.2E-58 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFA_RS09525 f31b6fa2a718fadcf73a4be2769ea3c8 152 Gene3D G3DSA:2.30.29.30 48 152 0.0014 T 28-03-2018 IPR011993 PH domain-like AFA_RS13135 8f7d45bcc098065a43c9169b6cc799c1 173 Pfam PF02620 Uncharacterized ACR, COG1399 59 171 1.9E-18 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD AFA_RS02170 173a04c24e672cae6419312d5e855871 237 Pfam PF01863 Protein of unknown function DUF45 25 230 1.0E-63 T 28-03-2018 IPR002725 Protein of unknown function DUF45 AFA_RS17920 8a1ead9281a43ec40990bcd063c58e99 680 Pfam PF05140 ResB-like family 21 669 2.3E-150 T 28-03-2018 IPR007816 ResB-like domain AFA_RS12125 b323a142e0bc33e4a0e1cd322f503758 225 Pfam PF07424 TrbM 26 192 6.5E-51 T 28-03-2018 IPR009989 TrbM AFA_RS01845 0355c8f20b7d321e9fd8d5a0b650f80a 205 Pfam PF03458 UPF0126 domain 91 163 4.7E-21 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 AFA_RS01845 0355c8f20b7d321e9fd8d5a0b650f80a 205 Pfam PF03458 UPF0126 domain 5 79 4.8E-18 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 AFA_RS02280 1e5e0c52122ff0feedbb689d6db6776e 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 264 3.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS02280 1e5e0c52122ff0feedbb689d6db6776e 280 Gene3D G3DSA:1.10.3720.10 17 268 1.6E-31 T 28-03-2018 AFA_RS02280 1e5e0c52122ff0feedbb689d6db6776e 280 SUPERFAMILY SSF161098 21 276 1.03E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AFA_RS14255 36be43fff330ba3d5427877ec8b6e4a7 248 Pfam PF01203 Type II secretion system (T2SS), protein N 64 238 1.9E-15 T 28-03-2018 IPR022792 Type II secretion system, protein N AFA_RS07480 c064205fbe0e13dd39e1a0eddfcc9926 225 Gene3D G3DSA:3.40.50.880 1 224 1.7E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07480 c064205fbe0e13dd39e1a0eddfcc9926 225 SUPERFAMILY SSF52317 1 224 1.87E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like AFA_RS07480 c064205fbe0e13dd39e1a0eddfcc9926 225 Pfam PF01965 DJ-1/PfpI family 25 221 4.3E-15 T 28-03-2018 IPR002818 DJ-1/PfpI AFA_RS04300 adf8292658cb071a0f4cc2a5ef0e1364 102 Pfam PF04341 Protein of unknown function, DUF485 11 97 5.0E-33 T 28-03-2018 IPR007436 Protein of unknown function DUF485 AFA_RS08440 983c9502dd1e32d77ac47e0c13cfc8d2 475 Pfam PF01425 Amidase 30 451 1.6E-88 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS08440 983c9502dd1e32d77ac47e0c13cfc8d2 475 SUPERFAMILY SSF75304 8 468 1.18E-111 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS08440 983c9502dd1e32d77ac47e0c13cfc8d2 475 Gene3D G3DSA:3.90.1300.10 12 462 3.1E-119 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFA_RS08440 983c9502dd1e32d77ac47e0c13cfc8d2 475 ProSitePatterns PS00571 Amidases signature. 158 189 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFA_RS04035 13774d9c1f473537659ef3d131fad029 159 SUPERFAMILY SSF54427 38 149 2.86E-25 T 28-03-2018 IPR032710 NTF2-like domain AFA_RS04035 13774d9c1f473537659ef3d131fad029 159 Pfam PF07366 SnoaL-like polyketide cyclase 43 148 4.8E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain AFA_RS04035 13774d9c1f473537659ef3d131fad029 159 Gene3D G3DSA:3.10.450.50 33 159 1.2E-26 T 28-03-2018 AFA_RS13695 d5ea245e1754fb87ffce274172d8e6b1 149 Pfam PF07811 TadE-like protein 1 39 1.6E-11 T 28-03-2018 IPR012495 TadE-like AFA_RS02225 6336fe5cda1ba40186e79b186069824a 555 Pfam PF02652 L-lactate permease 17 546 3.0E-219 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFA_RS02225 6336fe5cda1ba40186e79b186069824a 555 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 7 548 1.1E-226 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFA_RS03945 66be097651dd3cc2227123fde2aade48 159 Pfam PF10029 Predicted periplasmic protein (DUF2271) 26 152 7.8E-33 T 28-03-2018 IPR014469 Protein of unknown function DUF2271 AFA_RS00945 f55d9e7144ab535ac19112eb70a44784 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 296 3.5E-32 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS00945 f55d9e7144ab535ac19112eb70a44784 324 Gene3D G3DSA:3.20.20.80 21 268 5.4E-4 T 28-03-2018 AFA_RS06350 757e189c9c173edcc02f46eac54129c2 426 Pfam PF03743 Bacterial conjugation TrbI-like protein 232 412 6.6E-58 T 28-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI AFA_RS09845 8f516920702b690d38b473760f173795 129 Gene3D G3DSA:1.10.10.10 2 95 6.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain AFA_RS00730 bca4df62b7d87479cba52e6746bb8e54 115 Pfam PF08895 Domain of unknown function (DUF1840) 1 108 1.4E-31 T 28-03-2018 IPR014991 Protein of unknown function DUF1840 AFA_RS15615 bd97075c3ef99461b192f85da6d971e9 187 Pfam PF02325 YGGT family 12 80 2.3E-11 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 AFA_RS15615 bd97075c3ef99461b192f85da6d971e9 187 Pfam PF02325 YGGT family 110 177 4.5E-16 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 AFA_RS12110 b481fe452c6799745d80ec482ee5c3f0 110 Gene3D G3DSA:1.10.1220.10 6 42 3.0E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFA_RS16210 9e04f6782dcfa3ee821556ed074ab8f5 209 Pfam PF02036 SCP-2 sterol transfer family 20 115 2.9E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain AFA_RS12185 3687ed560beb44b329dd3aec59584df4 370 Pfam PF03743 Bacterial conjugation TrbI-like protein 181 357 1.1E-50 T 28-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI AFA_RS10125 bc328ad1ecbf51fffc432146d00d808c 277 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 276 72.965 T 28-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein AFA_RS10125 bc328ad1ecbf51fffc432146d00d808c 277 Pfam PF03618 Kinase/pyrophosphorylase 10 267 2.9E-80 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 AFA_RS07085 31184cdc6d8e941d720f400fd1438926 609 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 130 199 6.1E-15 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal AFA_RS07085 31184cdc6d8e941d720f400fd1438926 609 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 374 443 2.4E-9 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal AFA_RS07085 31184cdc6d8e941d720f400fd1438926 609 Gene3D G3DSA:1.20.1270.60 4 428 6.0E-4 T 28-03-2018 AFA_RS16255 f708755d72a2a06c1d06c94bcb8507f9 180 Pfam PF09335 SNARE associated Golgi protein 56 165 1.2E-9 T 28-03-2018 IPR032816 SNARE associated Golgi protein AFA_RS08105 c4a2542d8f75228b8d5b97b7f3350a24 540 Gene3D G3DSA:2.60.40.1220 33 126 1.4E-17 T 28-03-2018 AFA_RS08105 c4a2542d8f75228b8d5b97b7f3350a24 540 SUPERFAMILY SSF81296 33 125 8.4E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set AFA_RS08105 c4a2542d8f75228b8d5b97b7f3350a24 540 Pfam PF04234 CopC domain 34 125 6.9E-18 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 AFA_RS08105 c4a2542d8f75228b8d5b97b7f3350a24 540 Pfam PF05425 Copper resistance protein D 316 416 9.6E-21 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 AFA_RS12365 5f105dbdafb6c14c7b7e7c58ce7fb1f0 80 SUPERFAMILY SSF53098 3 68 9.86E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS12365 5f105dbdafb6c14c7b7e7c58ce7fb1f0 80 Gene3D G3DSA:3.30.420.10 1 73 2.3E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 AFA_RS09910 52d4617e1cdbf391b9c8098a82389f3d 134 Pfam PF13665 Domain of unknown function (DUF4150) 12 114 2.0E-31 T 28-03-2018 IPR025425 Domain of unknown function DUF4150 AFA_RS12165 5a282095277c2b30b5dcc401de914c50 268 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 31 250 1.0E-37 T 28-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 AFA_RS07070 3b417197dbdd1efab1b048661c67ec9b 139 Pfam PF13554 Bacteriophage related domain of unknown function 5 135 4.4E-7 T 28-03-2018 IPR025395 Protein of unknown function DUF4128 AFA_RS05010 2c22d942563e8395752a8576a46a82ef 376 SUPERFAMILY SSF53474 244 291 4.01E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS05010 2c22d942563e8395752a8576a46a82ef 376 SUPERFAMILY SSF53474 118 215 4.01E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS05010 2c22d942563e8395752a8576a46a82ef 376 Gene3D G3DSA:3.40.50.1820 99 351 2.7E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS09860 3aa72d8379080931b8e7bf25caca9349 201 Pfam PF11198 Protein of unknown function (DUF2857) 13 183 5.5E-23 T 28-03-2018 IPR021364 Protein of unknown function DUF2857 AFA_RS17080 6708069e9ff9aa26945eee9b27bce605 191 Pfam PF02417 Chromate transporter 14 172 7.4E-28 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFA_RS06075 1ae7d85de0735bf2175e8582265101da 438 Gene3D G3DSA:1.10.357.10 240 408 1.6E-4 T 28-03-2018 AFA_RS06075 1ae7d85de0735bf2175e8582265101da 438 Pfam PF04286 Protein of unknown function (DUF445) 60 434 2.5E-99 T 28-03-2018 IPR007383 Protein of unknown function DUF445 AFA_RS14730 fce4b9554a8f1212b080c58617a40217 296 SUPERFAMILY SSF103481 61 147 2.94E-8 T 28-03-2018 AFA_RS14730 fce4b9554a8f1212b080c58617a40217 296 SUPERFAMILY SSF103481 193 288 1.83E-9 T 28-03-2018 AFA_RS14730 fce4b9554a8f1212b080c58617a40217 296 Pfam PF00892 EamA-like transporter family 18 147 4.7E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS14730 fce4b9554a8f1212b080c58617a40217 296 Pfam PF00892 EamA-like transporter family 159 291 5.1E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFA_RS10425 55c0ad38ff092bab0d52208e4d0616c3 253 Gene3D G3DSA:3.40.50.150 8 250 1.3E-14 T 28-03-2018 AFA_RS10425 55c0ad38ff092bab0d52208e4d0616c3 253 SUPERFAMILY SSF53335 17 225 1.78E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFA_RS10985 d89305936bbfb05aef981f073e40355c 204 Pfam PF11136 Protein of unknown function (DUF2889) 26 150 4.9E-41 T 28-03-2018 IPR021312 Protein of unknown function DUF2889 AFA_RS14825 3307be54a8d4cd75f94f6032303d43db 127 Pfam PF01219 Prokaryotic diacylglycerol kinase 20 119 5.7E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFA_RS14825 3307be54a8d4cd75f94f6032303d43db 127 Gene3D G3DSA:1.10.3830.10 11 123 8.9E-39 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFA_RS17530 b81c3cbb69edfcc332725b61a08bc81e 74 Pfam PF11174 Protein of unknown function (DUF2970) 15 68 3.0E-22 T 28-03-2018 IPR021344 Protein of unknown function DUF2970 AFA_RS10335 5046981a8ba6060b8958d0c1fc586aea 351 PIRSF PIRSF006470 26 342 4.9E-70 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS10335 5046981a8ba6060b8958d0c1fc586aea 351 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 59 306 1.7E-53 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 AFA_RS10335 5046981a8ba6060b8958d0c1fc586aea 351 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 59 333 3.0E-67 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS02495 d5bd3a5d463bfe070d7bc41b5d617ac1 379 Pfam PF01699 Sodium/calcium exchanger protein 238 375 1.4E-5 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFA_RS02495 d5bd3a5d463bfe070d7bc41b5d617ac1 379 Pfam PF01699 Sodium/calcium exchanger protein 48 199 8.9E-15 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFA_RS06450 4c07804458a7d08b224c11f960773548 583 Pfam PF04632 Fusaric acid resistance protein family 245 521 6.8E-27 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 AFA_RS07400 26954cae90a0876b324062909abb5e2b 156 Pfam PF02643 Uncharacterized ACR, COG1430 47 148 1.4E-31 T 28-03-2018 IPR003795 Protein of unknown function DUF192 AFA_RS02920 75bb3a216860e59534d9161d240c110a 157 Pfam PF03918 Cytochrome C biogenesis protein 23 148 1.6E-45 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family AFA_RS15675 42f7151b417174dac10d61a8c67e246e 629 SMART SM00955 233 516 2.0E-58 T 28-03-2018 AFA_RS15675 42f7151b417174dac10d61a8c67e246e 629 SUPERFAMILY SSF50249 221 565 8.57E-71 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold AFA_RS15675 42f7151b417174dac10d61a8c67e246e 629 Pfam PF00773 RNB domain 241 469 2.2E-37 T 28-03-2018 AFA_RS15675 42f7151b417174dac10d61a8c67e246e 629 Pfam PF00773 RNB domain 471 513 1.1E-7 T 28-03-2018 AFA_RS03820 35c0788397b281f8b1944a25fd20bf71 409 PIRSF PIRSF036542 1 409 4.2E-197 T 28-03-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB AFA_RS03820 35c0788397b281f8b1944a25fd20bf71 409 Pfam PF07670 Nucleoside recognition 51 155 5.3E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFA_RS08660 1ef9576d1e3141bb29d8fe07e99109d3 81 Pfam PF03891 Domain of unknown function (DUF333) 31 74 8.9E-15 T 28-03-2018 IPR005590 Protein of unknown function DUF333 AFA_RS07635 3d67b6811c551f4a674ac0ba8a79b781 178 Pfam PF02293 AmiS/UreI family transporter 10 176 3.4E-36 T 28-03-2018 IPR003211 AmiS/UreI transporter GO:0006810|GO:0016020 AFA_RS00895 6711a925ac4a65f9ba72e5f902a95504 322 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 27 304 1.3E-35 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AFA_RS05300 61bcff6d9a64a2a6659e583a2f49cb38 259 Pfam PF01925 Sulfite exporter TauE/SafE 11 252 2.0E-45 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS06830 907a534b46a66525c2daf09666b6c90c 111 Pfam PF06356 Protein of unknown function (DUF1064) 3 100 8.7E-28 T 28-03-2018 IPR009414 Protein of unknown function DUF1064 AFA_RS06830 907a534b46a66525c2daf09666b6c90c 111 Gene3D G3DSA:3.40.91.30 15 111 1.7E-9 T 28-03-2018 AFA_RS00605 d442757add762a71492fcd4b0594ebb0 173 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 39 170 6.8E-27 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS01000 e13855c81008f07024f339758ed13296 336 Pfam PF01757 Acyltransferase family 2 322 3.7E-36 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 AFA_RS18060 f4d4fcaae0f084ca8b8544a308819a47 209 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 53 163 3.5E-12 T 28-03-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted AFA_RS09070 5324ec073b182d5f9d5f02306b70b71c 297 Pfam PF05742 Transport and Golgi organisation 2 1 249 6.3E-59 T 28-03-2018 IPR008551 Transport and Golgi organisation protein 2 AFA_RS14565 1867ad2c2aacd063e4da83efdd52b1cd 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 1.9E-154 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane AFA_RS01160 92e01279cb832fcaae916de58f3a0d80 227 Pfam PF11010 Protein of unknown function (DUF2848) 26 218 1.3E-76 T 28-03-2018 IPR021269 Protein of unknown function DUF2848 AFA_RS00635 67f5ca1f72799dbe3d2f90834447d64d 144 PIRSF PIRSF015875 1 144 1.1E-39 T 28-03-2018 IPR007418 Protein of unknown function DUF474 AFA_RS10770 eec0fa23d241f16642563363a9ae5d83 557 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 15 515 4.5E-116 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFA_RS03005 f7960631dfba9d459f8509f423d0e7a2 518 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 54 218 4.1E-16 T 28-03-2018 AFA_RS13650 6287ceacec8f8e9429ba21feafc4d45c 162 Pfam PF12266 Protein of unknown function (DUF3613) 99 154 6.9E-8 T 28-03-2018 IPR022053 Protein of unknown function DUF3613 AFA_RS04470 a6e540e2b28bd1dac7c0371a7a5cd272 320 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 34 301 9.0E-68 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 AFA_RS04640 6d3b48281799dd53274eabc40d1c1b5a 106 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 4.3E-36 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AFA_RS09895 317fea6fdeec22053151721f11f2c898 230 Pfam PF09850 Type VI secretion system protein DotU 16 216 4.2E-37 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU AFA_RS09895 317fea6fdeec22053151721f11f2c898 230 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 30 222 5.5E-32 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU AFA_RS18330 10cabb11ea61dfecddf813a3bb4d1d89 211 Pfam PF01810 LysE type translocator 14 202 8.9E-24 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFA_RS08695 cc064bedc9a4daa218b5c5ccb67a995b 161 SUPERFAMILY SSF58113 54 145 9.02E-6 T 28-03-2018 AFA_RS08695 cc064bedc9a4daa218b5c5ccb67a995b 161 Gene3D G3DSA:1.20.120.20 40 149 6.6E-9 T 28-03-2018 AFA_RS07025 634d5c7166771966dd7f12fa3ea09fed 106 ProDom PD052090 YDCA PRECURSOR SIGNAL ECS2024 8 53 6.0E-9 T 28-03-2018 AFA_RS14015 1340899468e12310eac12220cd90d06f 148 Pfam PF09361 Phasin protein 10 101 5.7E-7 T 28-03-2018 IPR018968 Phasin AFA_RS06855 052381600dbdc029b93e75bae67df779 157 Pfam PF10045 Uncharacterized conserved protein (DUF2280) 1 102 4.7E-43 T 28-03-2018 IPR018738 Protein of unknown function DUF2280 AFA_RS05590 99f9e85cec1f2f7e68232793d7df9cbb 328 Pfam PF06674 Protein of unknown function (DUF1176) 12 319 1.9E-90 T 28-03-2018 IPR009560 Protein of unknown function DUF1176 AFA_RS17015 7ff534653b9866f2922d02a1f066b0a0 396 Gene3D G3DSA:3.30.1890.10 55 365 5.2E-21 T 28-03-2018 AFA_RS06195 e4d30a12b301b3590bb8777ccca48785 98 Pfam PF12365 Protein of unknown function (DUF3649) 64 90 2.3E-10 T 28-03-2018 IPR022109 Protein of unknown function DUF3649 AFA_RS05935 6402e5439f424269f2b79542c363f779 360 Pfam PF02120 Flagellar hook-length control protein FliK 229 309 2.7E-21 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal AFA_RS02070 aa81e23a9ad48bd98efdff5601b88578 260 Pfam PF01925 Sulfite exporter TauE/SafE 5 253 8.0E-44 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS14380 cc694686b016ed7495f92db309fa61d0 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 10 107 3.2E-18 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD AFA_RS10955 fce2e976985ee23519819c6325b24631 452 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 46 389 1.5E-42 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX AFA_RS00900 1d1836e05894419f71d4c9f43e9fabca 163 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 153 8.7E-26 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS14200 d0e421c92419bc594dc9072ea1f26035 65 Gene3D G3DSA:3.40.190.10 10 57 2.9E-5 T 28-03-2018 AFA_RS03010 df5d364766610d2d75cd4b8c1eb56e25 125 Pfam PF04138 GtrA-like protein 8 122 2.6E-16 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 AFA_RS03915 daf8daa4adc455568b88718b8667c898 486 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 22 461 1.6E-75 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 AFA_RS02825 9b882379a8b5a5f1b4841eebbfe1cac3 273 Pfam PF02517 CAAX protease self-immunity 92 254 1.2E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFA_RS09540 28e79499d9b2c153048c23d5045259be 184 TIGRFAM TIGR03748 conj_PilL: integrating conjugative element protein PilL, PFGI-1 class 34 138 6.5E-22 T 28-03-2018 IPR022260 Integrating conjugative element protein PilL, PFGI-1 AFA_RS01520 39690d234f7cffb912eb47b9aec4c43c 259 Gene3D G3DSA:3.40.50.1820 5 255 1.2E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS01520 39690d234f7cffb912eb47b9aec4c43c 259 SUPERFAMILY SSF53474 12 253 1.79E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold AFA_RS13030 c2e3f10f1c5df9ccd1b84cded690aa8a 236 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 26 228 4.2E-42 T 28-03-2018 IPR006214 Bax inhibitor 1-related AFA_RS01330 aad07754f435d6d60debf24fd4f13279 60 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 10 46 6.5E-9 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 AFA_RS06465 257c5eeb69d3714482cdfc04ee1484d7 189 Pfam PF03729 Short repeat of unknown function (DUF308) 27 95 6.3E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane AFA_RS06465 257c5eeb69d3714482cdfc04ee1484d7 189 Pfam PF03729 Short repeat of unknown function (DUF308) 82 150 9.0E-12 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane AFA_RS08815 40f4889d3e4e1a3b307e5f47ef3e3872 144 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 8 141 1.9E-31 T 28-03-2018 IPR018893 Type VIII secretion system, CsgF AFA_RS13630 5c36f24cad266039d1230ecc1669a8cc 390 Pfam PF05762 VWA domain containing CoxE-like protein 184 272 3.5E-11 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like AFA_RS09490 151a585ad6f9857ba74033d8c7c9b71c 105 Pfam PF13663 Domain of unknown function (DUF4148) 1 75 3.2E-12 T 28-03-2018 IPR025421 Protein of unknown function DUF4148 AFA_RS11950 ac1451bffec763cd572466bf3448cf9c 110 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 87 8.2E-19 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 AFA_RS17290 13254f30020c363edeaa0f1e187f76c6 148 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 4 132 1.1E-19 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS16790 aaa4f9d029920fede1c8d57e505da3ae 147 PIRSF PIRSF015875 1 147 2.4E-48 T 28-03-2018 IPR007418 Protein of unknown function DUF474 AFA_RS08600 ca1933d8ce4a559578e2aae985a963f5 234 Pfam PF01925 Sulfite exporter TauE/SafE 8 229 2.5E-24 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFA_RS06815 056eb7ce94aec618cfb073a1eebb78c4 119 Pfam PF16786 Recombination enhancement, RecA-dependent nuclease 7 97 4.9E-29 T 28-03-2018 IPR031875 Recombination enhancement, RecA-dependent nuclease AFA_RS15305 a8895af47c95adc2413ad3753a049375 175 Pfam PF10649 Protein of unknown function (DUF2478) 10 167 6.4E-51 T 28-03-2018 IPR018912 Protein of unknown function DUF2478 AFA_RS06720 972e044ee9ddba15f4edaefbe94a2378 254 Pfam PF04404 ERF superfamily 61 194 5.3E-19 T 28-03-2018 IPR007499 Essential recombination function protein AFA_RS16550 b712d2b848020d202f9d7c496a1b5b9a 428 Pfam PF01943 Polysaccharide biosynthesis protein 11 279 3.7E-23 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFA_RS04505 26855d29b8d09bbefee8235270e30288 469 Pfam PF02667 Short chain fatty acid transporter 16 463 1.0E-107 T 28-03-2018 IPR006160 Short chain fatty acid transporter AtoE AFA_RS06785 4d441322020c174b29e99272a57cb5cc 128 Gene3D G3DSA:1.10.260.40 3 69 2.1E-6 T 28-03-2018 AFA_RS06645 0e44825fd3e69ee5789f00a5a949b109 172 Pfam PF09335 SNARE associated Golgi protein 43 166 7.7E-13 T 28-03-2018 IPR032816 SNARE associated Golgi protein AFA_RS08285 66b01a3c6867a89501f17f169d6daff0 290 Pfam PF02535 ZIP Zinc transporter 146 285 8.8E-17 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFA_RS00950 f6af938cddbd33c14486ab226c3c74f4 174 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 38 168 4.8E-26 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AFA_RS12660 44a95d51eeb382f4b65212cc57cb01f8 215 Pfam PF13590 Domain of unknown function (DUF4136) 37 200 8.0E-20 T 28-03-2018 IPR025411 Domain of unknown function DUF4136 AFA_RS02570 b59bd55cc63facd0b2f1840490107550 1337 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 988 1333 4.9E-38 T 28-03-2018 IPR007452 Translocation and assembly module TamB