locus-tag	class	description
ALFP_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALFP_RS00010	COG0592	DNA-directed DNA polymerase activity
ALFP_RS00020	COG1187	pseudouridine synthase activity
ALFP_RS00035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS00060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS00065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALFP_RS00085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS00105	COG2070	2-Nitropropane dioxygenase
ALFP_RS00125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS00145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS00165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALFP_RS00170	COG0583	DNA-binding transcription factor activity
ALFP_RS00180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS00190	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS00205	COG0318	PFAM AMP-dependent synthetase and ligase
ALFP_RS00215	COG0596	Alpha beta hydrolase
ALFP_RS00215	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALFP_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS00235	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS00245	COG0697	spore germination
ALFP_RS00250	COG0583	DNA-binding transcription factor activity
ALFP_RS00260	COG3842	ATPase activity
ALFP_RS00270	COG0436	Aminotransferase
ALFP_RS00280	COG0523	cobalamin synthesis protein
ALFP_RS00335	COG1846	Transcriptional regulator
ALFP_RS00355	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALFP_RS00360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFP_RS00365	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ALFP_RS00375	COG4638	Rieske (2fe-2S)
ALFP_RS00435	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS00455	COG2207	Transcriptional regulator
ALFP_RS00490	COG1595	DNA-templated transcription, initiation
ALFP_RS00495	COG4608	Belongs to the ABC transporter superfamily
ALFP_RS00500	COG0444	Belongs to the ABC transporter superfamily
ALFP_RS00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALFP_RS00510	COG0601	transmembrane transport
ALFP_RS00520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALFP_RS00525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALFP_RS00535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALFP_RS00540	COG0431	NADPH-dependent FMN reductase
ALFP_RS00570	COG4149	molybdate abc transporter
ALFP_RS00580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ALFP_RS00585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALFP_RS00595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALFP_RS00615	COG0028	Belongs to the TPP enzyme family
ALFP_RS00620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALFP_RS00640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALFP_RS00640	COG0551	DNA topoisomerase type I activity
ALFP_RS00650	COG2922	Belongs to the Smg family
ALFP_RS00665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALFP_RS00670	COG0183	Belongs to the thiolase family
ALFP_RS00675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALFP_RS00680	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS00700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALFP_RS00710	COG0018	arginyl-trna synthetase
ALFP_RS00730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALFP_RS00740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ALFP_RS00745	COG4774	siderophore transport
ALFP_RS00750	COG0066	3-isopropylmalate dehydratase activity
ALFP_RS00755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALFP_RS00760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALFP_RS00765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS00770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS00770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALFP_RS00780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS00785	COG1335	isochorismatase
ALFP_RS00790	COG0583	DNA-binding transcription factor activity
ALFP_RS00810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ALFP_RS00815	COG1280	lysine exporter protein (LysE YggA)
ALFP_RS00820	COG0513	Belongs to the DEAD box helicase family
ALFP_RS00830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ALFP_RS00845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALFP_RS00860	COG0154	amidase activity
ALFP_RS00875	COG0583	DNA-binding transcription factor activity
ALFP_RS00905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALFP_RS00910	COG1127	ABC transporter
ALFP_RS00915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALFP_RS00915	COG3218	ABC-type transport auxiliary lipoprotein component
ALFP_RS00930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALFP_RS00935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALFP_RS00945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS00970	COG0583	DNA-binding transcription factor activity
ALFP_RS00995	COG4680	protein conserved in bacteria
ALFP_RS01015	COG2358	TRAP transporter, solute receptor (TAXI family
ALFP_RS01025	COG0564	pseudouridine synthase activity
ALFP_RS01030	COG0252	asparaginase activity
ALFP_RS01055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALFP_RS01060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALFP_RS01065	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS01085	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS01110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS01125	COG0758	DNA mediated transformation
ALFP_RS01130	COG0242	peptide deformylase activity
ALFP_RS01135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALFP_RS01140	COG0697	spore germination
ALFP_RS01155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS01170	COG4336	lyase activity
ALFP_RS01175	COG0583	DNA-binding transcription factor activity
ALFP_RS01180	COG0859	PFAM glycosyl transferase family 9
ALFP_RS01190	COG1278	Cold shock
ALFP_RS01195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ALFP_RS01200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALFP_RS01205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ALFP_RS01205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ALFP_RS01215	COG1686	Belongs to the peptidase S11 family
ALFP_RS01225	COG2921	Belongs to the UPF0250 family
ALFP_RS01230	COG0321	lipoyl(octanoyl) transferase activity
ALFP_RS01235	COG1024	Enoyl-CoA hydratase
ALFP_RS01240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALFP_RS01250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALFP_RS01295	COG0826	peptidase U32
ALFP_RS01305	COG3154	lipid carrier protein
ALFP_RS01330	COG0134	indole-3-glycerol-phosphate synthase activity
ALFP_RS01335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALFP_RS01340	COG0512	Glutamine amidotransferase of anthranilate synthase
ALFP_RS01350	COG0546	phosphoglycolate phosphatase activity
ALFP_RS01360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALFP_RS01365	COG2967	ApaG domain
ALFP_RS01370	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ALFP_RS01375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS01380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALFP_RS01390	COG0840	transmembrane signaling receptor activity
ALFP_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS01405	COG1535	isochorismatase
ALFP_RS01405	COG3433	isochorismatase activity
ALFP_RS01410	COG1169	isochorismate synthase
ALFP_RS01425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ALFP_RS01425	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ALFP_RS01430	COG1535	isochorismatase
ALFP_RS01430	COG3433	isochorismatase activity
ALFP_RS01435	COG1021	2,3-dihydroxybenzoate-AMP ligase
ALFP_RS01465	COG0683	leucine binding
ALFP_RS01480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS01515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ALFP_RS01520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALFP_RS01525	COG2819	hydrolase of the alpha beta superfamily
ALFP_RS01530	COG0513	Belongs to the DEAD box helicase family
ALFP_RS01535	COG2814	Major facilitator Superfamily
ALFP_RS01545	COG0583	DNA-binding transcription factor activity
ALFP_RS01555	COG1253	flavin adenine dinucleotide binding
ALFP_RS01590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALFP_RS01600	COG2311	Membrane
ALFP_RS01635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALFP_RS01655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS01660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALFP_RS01670	COG0583	DNA-binding transcription factor activity
ALFP_RS01675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS01685	COG0765	amino acid transport
ALFP_RS01690	COG0765	amino acid transport
ALFP_RS01695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALFP_RS01710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALFP_RS01725	COG3391	amine dehydrogenase activity
ALFP_RS01735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALFP_RS01760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALFP_RS01765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALFP_RS01770	COG0210	DNA helicase
ALFP_RS01790	COG0069	glutamate synthase activity
ALFP_RS01790	COG0067	glutamate synthase
ALFP_RS01790	COG0070	glutamate synthase
ALFP_RS01795	COG1024	Enoyl-CoA hydratase
ALFP_RS01805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS01810	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALFP_RS01840	COG2918	glutathione biosynthetic process
ALFP_RS01850	COG2197	response regulator
ALFP_RS01855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALFP_RS01865	COG2223	nitrite transmembrane transporter activity
ALFP_RS01870	COG2860	membrane
ALFP_RS01875	COG1346	cytolysis
ALFP_RS01890	COG0251	oxidation-reduction process
ALFP_RS01905	COG5295	Hep Hag repeat protein
ALFP_RS01925	COG1280	lysine exporter protein (LysE YggA)
ALFP_RS01935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALFP_RS01950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ALFP_RS01965	COG2096	Adenosyltransferase
ALFP_RS01980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALFP_RS01985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALFP_RS01995	COG0523	cobalamin synthesis protein
ALFP_RS02000	COG0735	belongs to the Fur family
ALFP_RS02010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ALFP_RS02015	COG0803	Belongs to the bacterial solute-binding protein 9 family
ALFP_RS02020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALFP_RS02030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALFP_RS02035	COG1560	Kdo2-lipid A biosynthetic process
ALFP_RS02045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALFP_RS02050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALFP_RS02055	COG1950	PFAM Membrane protein of
ALFP_RS02090	COG0275	rRNA processing
ALFP_RS02095	COG0730	response to heat
ALFP_RS02100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALFP_RS02105	COG0129	dihydroxy-acid dehydratase activity
ALFP_RS02110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ALFP_RS02130	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS02140	COG0628	permease
ALFP_RS02240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALFP_RS02265	COG4804	nuclease activity
ALFP_RS02280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS02320	COG1021	2,3-dihydroxybenzoate-AMP ligase
ALFP_RS02335	COG2814	Major facilitator Superfamily
ALFP_RS02345	COG0656	L-ascorbic acid biosynthetic process
ALFP_RS02350	COG2814	Major facilitator Superfamily
ALFP_RS02355	COG0583	DNA-binding transcription factor activity
ALFP_RS02365	COG3685	Protein conserved in bacteria
ALFP_RS02385	COG1846	Transcriptional regulator
ALFP_RS02400	COG4774	siderophore transport
ALFP_RS02405	COG4607	ABC-type enterochelin transport system periplasmic component
ALFP_RS02410	COG4604	ABC transporter, ATP-binding protein
ALFP_RS02415	COG4605	iron ion homeostasis
ALFP_RS02420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALFP_RS02425	COG1132	(ABC) transporter
ALFP_RS02430	COG1132	(ABC) transporter
ALFP_RS02430	COG2375	cellular response to nickel ion
ALFP_RS02435	COG0277	FAD linked oxidase domain protein
ALFP_RS02440	COG1304	FMN binding
ALFP_RS02445	COG2186	Transcriptional regulator
ALFP_RS02465	COG2188	Transcriptional regulator
ALFP_RS02470	COG1522	sequence-specific DNA binding
ALFP_RS02475	COG3844	kynureninase activity
ALFP_RS02480	COG1113	amino acid transport
ALFP_RS02510	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS02515	COG1349	DNA-binding transcription factor activity
ALFP_RS02520	COG3842	ATPase activity
ALFP_RS02535	COG0395	ABC-type sugar transport system, permease component
ALFP_RS02560	COG0861	Integral membrane protein TerC family
ALFP_RS02565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALFP_RS02575	COG1671	Belongs to the UPF0178 family
ALFP_RS02585	COG1418	mRNA catabolic process
ALFP_RS02595	COG4948	Mandelate Racemase Muconate Lactonizing
ALFP_RS02605	COG0477	Major facilitator Superfamily
ALFP_RS02620	COG0154	amidase activity
ALFP_RS02630	COG0583	DNA-binding transcription factor activity
ALFP_RS02655	COG0326	Molecular chaperone. Has ATPase activity
ALFP_RS02660	COG4774	siderophore transport
ALFP_RS02665	COG3128	pkhd-type hydroxylase
ALFP_RS02690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALFP_RS02695	COG1652	LysM domain
ALFP_RS02710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALFP_RS02735	COG1535	isochorismatase
ALFP_RS02735	COG3433	isochorismatase activity
ALFP_RS02760	COG0583	DNA-binding transcription factor activity
ALFP_RS02765	COG0387	Pfam Sodium calcium exchanger
ALFP_RS02780	COG0477	Major facilitator Superfamily
ALFP_RS02785	COG0235	Class ii aldolase
ALFP_RS02800	COG0590	tRNA wobble adenosine to inosine editing
ALFP_RS02805	COG3257	ureidoglycine aminohydrolase activity
ALFP_RS02810	COG0583	DNA-binding transcription factor activity
ALFP_RS02815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALFP_RS02820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALFP_RS02820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALFP_RS02830	COG0489	protein tyrosine kinase activity
ALFP_RS02855	COG2081	HI0933 family
ALFP_RS02860	COG0509	glycine decarboxylation via glycine cleavage system
ALFP_RS02870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALFP_RS02875	COG1765	OsmC-like protein
ALFP_RS02880	COG3278	Belongs to the heme-copper respiratory oxidase family
ALFP_RS02905	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ALFP_RS02910	COG0469	pyruvate kinase activity
ALFP_RS02915	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ALFP_RS02925	COG2084	Dehydrogenase
ALFP_RS02930	COG3622	Belongs to the hyi family
ALFP_RS02935	COG3960	tartronate-semialdehyde synthase activity
ALFP_RS02940	COG0583	DNA-binding transcription factor activity
ALFP_RS02950	COG2233	PERMEase
ALFP_RS02955	COG1942	4-Oxalocrotonate Tautomerase
ALFP_RS02960	COG0235	Class ii aldolase
ALFP_RS02970	COG3195	allantoin biosynthetic process
ALFP_RS02970	COG3648	Uricase
ALFP_RS02980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALFP_RS02985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALFP_RS03000	COG0438	transferase activity, transferring glycosyl groups
ALFP_RS03010	COG0438	transferase activity, transferring glycosyl groups
ALFP_RS03020	COG0277	FAD linked oxidase domain protein
ALFP_RS03030	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALFP_RS03035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ALFP_RS03045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS03055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ALFP_RS03065	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ALFP_RS03080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALFP_RS03085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALFP_RS03090	COG0193	aminoacyl-tRNA hydrolase activity
ALFP_RS03100	COG0012	GTP binding
ALFP_RS03130	COG0488	(ABC) transporter
ALFP_RS03145	COG0288	reversible hydration of carbon dioxide
ALFP_RS03150	COG0583	DNA-binding transcription factor activity
ALFP_RS03180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ALFP_RS03190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALFP_RS03195	COG3088	subunit of a heme lyase
ALFP_RS03200	COG4235	cytochrome complex assembly
ALFP_RS03205	COG0785	Cytochrome C biogenesis protein
ALFP_RS03215	COG2169	Transcriptional regulator
ALFP_RS03215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALFP_RS03235	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS03245	COG0411	ABC transporter
ALFP_RS03255	COG1858	cytochrome C peroxidase
ALFP_RS03260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALFP_RS03265	COG1959	2 iron, 2 sulfur cluster binding
ALFP_RS03270	COG2346	COG2346, Truncated hemoglobins
ALFP_RS03275	COG0463	Glycosyl transferase, family 2
ALFP_RS03315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ALFP_RS03320	COG3383	formate dehydrogenase (NAD+) activity
ALFP_RS03335	COG1910	domain protein
ALFP_RS03340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALFP_RS03350	COG0303	'Molybdopterin
ALFP_RS03355	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALFP_RS03360	COG0314	molybdopterin synthase activity
ALFP_RS03370	COG0315	cyclic pyranopterin monophosphate synthase activity
ALFP_RS03400	COG0678	peroxiredoxin activity
ALFP_RS03415	COG0697	spore germination
ALFP_RS03420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALFP_RS03505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALFP_RS03510	COG4535	Mg2 and Co2 transporter CorC
ALFP_RS03515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALFP_RS03520	COG1702	phosphate starvation-inducible protein PhoH
ALFP_RS03525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALFP_RS03540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALFP_RS03545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALFP_RS03550	COG1862	Preprotein translocase
ALFP_RS03555	COG0343	queuine tRNA-ribosyltransferase activity
ALFP_RS03560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALFP_RS03565	COG2027	D-alanyl-D-alanine carboxypeptidase
ALFP_RS03570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALFP_RS03580	COG4575	ribosome binding
ALFP_RS03595	COG0583	DNA-binding transcription factor activity
ALFP_RS03610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALFP_RS03625	COG0154	amidase activity
ALFP_RS03635	COG0477	Major facilitator Superfamily
ALFP_RS03650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ALFP_RS03660	COG0436	Aminotransferase
ALFP_RS03670	COG0280	phosphate acetyltransferase
ALFP_RS03670	COG0281	malic enzyme
ALFP_RS03680	COG2732	(Barnase) inhibitor
ALFP_RS03685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALFP_RS03690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALFP_RS03695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALFP_RS03700	COG0126	phosphoglycerate kinase activity
ALFP_RS03720	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALFP_RS03730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALFP_RS03735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALFP_RS03740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALFP_RS03745	COG0009	L-threonylcarbamoyladenylate synthase
ALFP_RS03750	COG0596	Alpha beta hydrolase
ALFP_RS03755	COG2030	dehydratase
ALFP_RS03755	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS03760	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS03770	COG0405	Gamma-glutamyltransferase
ALFP_RS03780	COG0579	oxidoreductase
ALFP_RS03785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALFP_RS03790	COG0259	pyridoxamine-phosphate oxidase activity
ALFP_RS03800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALFP_RS03815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALFP_RS03825	COG1215	transferase activity, transferring glycosyl groups
ALFP_RS03835	COG0488	(ABC) transporter
ALFP_RS03855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ALFP_RS03860	COG2894	cell division
ALFP_RS03870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALFP_RS03875	COG1271	oxidase subunit
ALFP_RS03880	COG1294	oxidase, subunit
ALFP_RS03885	COG0038	chloride channel
ALFP_RS03895	COG0514	ATP-dependent DNA helicase (RecQ)
ALFP_RS03900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALFP_RS03905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALFP_RS03910	COG0633	Ferredoxin
ALFP_RS03915	COG0488	(ABC) transporter
ALFP_RS03925	COG2001	Belongs to the MraZ family
ALFP_RS03930	COG0275	rRNA processing
ALFP_RS03935	COG3116	cell division
ALFP_RS03945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALFP_RS03950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALFP_RS03955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALFP_RS03965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALFP_RS03970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALFP_RS03975	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALFP_RS03980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ALFP_RS03995	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALFP_RS04005	COG0739	heme binding
ALFP_RS04005	COG1196	nuclear chromosome segregation
ALFP_RS04005	COG0741	lytic transglycosylase activity
ALFP_RS04010	COG0653	protein targeting
ALFP_RS04020	COG2239	Acts as a magnesium transporter
ALFP_RS04030	COG1473	amidohydrolase
ALFP_RS04035	COG0318	PFAM AMP-dependent synthetase and ligase
ALFP_RS04045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ALFP_RS04045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS04060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ALFP_RS04065	COG2011	ABC-type metal ion transport system permease component
ALFP_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS04080	COG0765	amino acid transport
ALFP_RS04085	COG1126	abc transporter atp-binding protein
ALFP_RS04110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALFP_RS04115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALFP_RS04120	COG0700	Nucleoside recognition
ALFP_RS04135	COG0204	Acyl-transferase
ALFP_RS04140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ALFP_RS04145	COG0751	glycine-tRNA ligase activity
ALFP_RS04150	COG0752	glycyl-tRNA synthetase alpha subunit
ALFP_RS04155	COG1024	Enoyl-CoA hydratase
ALFP_RS04165	COG1309	transcriptional regulator
ALFP_RS04175	COG2814	Major facilitator Superfamily
ALFP_RS04190	COG1573	uracil-dna glycosylase
ALFP_RS04195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALFP_RS04200	COG0617	tRNA 3'-terminal CCA addition
ALFP_RS04210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALFP_RS04215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALFP_RS04220	COG1953	Uracil, thiamine, allantoin
ALFP_RS04225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALFP_RS04230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ALFP_RS04235	COG0586	Pfam SNARE associated Golgi protein
ALFP_RS04240	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALFP_RS04245	COG0802	atpase or kinase
ALFP_RS04255	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS04260	COG0281	malic enzyme
ALFP_RS04260	COG0280	phosphate acetyltransferase
ALFP_RS04265	COG0583	DNA-binding transcription factor activity
ALFP_RS04270	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS04275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALFP_RS04295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALFP_RS04320	COG1733	regulation of RNA biosynthetic process
ALFP_RS04325	COG2910	NAD(P)H-binding
ALFP_RS04335	COG2223	nitrite transmembrane transporter activity
ALFP_RS04340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ALFP_RS04345	COG4974	Belongs to the 'phage' integrase family
ALFP_RS04350	COG0725	ABC transporter, periplasmic molybdate-binding protein
ALFP_RS04355	COG4149	molybdate abc transporter
ALFP_RS04360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALFP_RS04375	COG1074	ATP-dependent DNA helicase activity
ALFP_RS04410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS04430	COG3391	amine dehydrogenase activity
ALFP_RS04435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALFP_RS04440	COG0505	Belongs to the CarA family
ALFP_RS04445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALFP_RS04465	COG2233	PERMEase
ALFP_RS04470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALFP_RS04475	COG1534	Rna-binding protein
ALFP_RS04480	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ALFP_RS04485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALFP_RS04490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALFP_RS04495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALFP_RS04505	COG0248	Ppx GppA phosphatase
ALFP_RS04510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALFP_RS04530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALFP_RS04535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALFP_RS04585	COG1231	oxidoreductase activity
ALFP_RS04590	COG2010	Cytochrome c
ALFP_RS04595	COG2323	membrane
ALFP_RS04610	COG1368	sulfuric ester hydrolase activity
ALFP_RS04640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALFP_RS04645	COG3327	negative regulation of DNA-templated transcription, initiation
ALFP_RS04650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALFP_RS04665	COG0009	L-threonylcarbamoyladenylate synthase
ALFP_RS04670	COG1994	Peptidase M50
ALFP_RS04675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALFP_RS04680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ALFP_RS04695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ALFP_RS04705	COG0156	8-amino-7-oxononanoate synthase activity
ALFP_RS04710	COG2124	cytochrome p450
ALFP_RS04720	COG3135	benzoate transporter
ALFP_RS04725	COG2850	peptidyl-arginine hydroxylation
ALFP_RS04730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALFP_RS04735	COG3391	amine dehydrogenase activity
ALFP_RS04745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALFP_RS04750	COG1136	(ABC) transporter
ALFP_RS04750	COG0577	efflux transmembrane transporter activity
ALFP_RS04755	COG1538	Outer membrane efflux protein
ALFP_RS04760	COG0363	glucosamine-6-phosphate deaminase activity
ALFP_RS04765	COG1132	(ABC) transporter
ALFP_RS04785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALFP_RS04795	COG0668	transmembrane transport
ALFP_RS04805	COG3321	synthase
ALFP_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS04805	COG0604	alcohol dehydrogenase
ALFP_RS04840	COG0154	amidase activity
ALFP_RS04855	COG0483	inositol monophosphate 1-phosphatase activity
ALFP_RS04860	COG1253	flavin adenine dinucleotide binding
ALFP_RS04865	COG1968	undecaprenyl-diphosphatase activity
ALFP_RS04890	COG0215	cysteine-tRNA ligase activity
ALFP_RS04900	COG0825	malonyl-CoA metabolic process
ALFP_RS04905	COG0037	tRNA processing
ALFP_RS04925	COG0330	HflC and HflK could
ALFP_RS04940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFP_RS04960	COG4208	sulfate ABC transporter
ALFP_RS04965	COG3842	ATPase activity
ALFP_RS04975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ALFP_RS05010	COG1304	FMN binding
ALFP_RS05015	COG0435	Glutathione S-transferase
ALFP_RS05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
ALFP_RS05040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALFP_RS05045	COG2363	Small membrane protein
ALFP_RS05050	COG0598	Magnesium transport protein CorA
ALFP_RS05055	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALFP_RS05080	COG4172	Belongs to the ABC transporter superfamily
ALFP_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS05100	COG1454	alcohol dehydrogenase
ALFP_RS05105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALFP_RS05130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS05160	COG3829	transcription factor binding
ALFP_RS05165	COG0477	Major facilitator Superfamily
ALFP_RS05175	COG0039	L-malate dehydrogenase activity
ALFP_RS05180	COG2188	Transcriptional regulator
ALFP_RS05185	COG2009	succinate dehydrogenase
ALFP_RS05195	COG1053	succinate dehydrogenase
ALFP_RS05200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALFP_RS05205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ALFP_RS05210	COG0372	Belongs to the citrate synthase family
ALFP_RS05215	COG2186	Transcriptional regulator
ALFP_RS05220	COG1620	l-lactate permease
ALFP_RS05225	COG0280	phosphate acetyltransferase
ALFP_RS05225	COG0281	malic enzyme
ALFP_RS05235	COG0567	Dehydrogenase, E1 component
ALFP_RS05240	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALFP_RS05245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALFP_RS05250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ALFP_RS05270	COG2183	response to ionizing radiation
ALFP_RS05275	COG1199	ATP-dependent helicase activity
ALFP_RS05285	COG1733	regulation of RNA biosynthetic process
ALFP_RS05300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS05300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ALFP_RS05305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALFP_RS05315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS05315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALFP_RS05330	COG0564	pseudouridine synthase activity
ALFP_RS05340	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALFP_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS05350	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ALFP_RS05380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALFP_RS05385	COG1187	pseudouridine synthase activity
ALFP_RS05390	COG0779	Required for maturation of 30S ribosomal subunits
ALFP_RS05395	COG0195	Participates in both transcription termination and antitermination
ALFP_RS05395	COG2251	uridine kinase activity
ALFP_RS05400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALFP_RS05405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALFP_RS05410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALFP_RS05415	COG1217	gtp-binding protein TYPA
ALFP_RS05420	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALFP_RS05430	COG4160	amino acid transport
ALFP_RS05435	COG4215	(ABC) transporter
ALFP_RS05455	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALFP_RS05465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALFP_RS05475	COG0456	acetyltransferase
ALFP_RS05480	COG0501	Belongs to the peptidase M48B family
ALFP_RS05495	COG1722	exodeoxyribonuclease VII activity
ALFP_RS05500	COG0142	geranyltranstransferase activity
ALFP_RS05510	COG1469	GTP cyclohydrolase I activity
ALFP_RS05515	COG0360	Binds together with S18 to 16S ribosomal RNA
ALFP_RS05520	COG2965	DNA replication, synthesis of RNA primer
ALFP_RS05525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALFP_RS05535	COG0305	Participates in initiation and elongation during chromosome replication
ALFP_RS05545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALFP_RS05550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALFP_RS05555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALFP_RS05565	COG0436	Aminotransferase
ALFP_RS05580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALFP_RS05585	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ALFP_RS05590	COG1562	ergosterol biosynthetic process
ALFP_RS05595	COG1562	ergosterol biosynthetic process
ALFP_RS05600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALFP_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS05630	COG3842	ATPase activity
ALFP_RS05635	COG1176	ABC-type spermidine putrescine transport system, permease component I
ALFP_RS05640	COG1177	transmembrane transport
ALFP_RS05645	COG1393	Belongs to the ArsC family
ALFP_RS05650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALFP_RS05655	COG0704	Plays a role in the regulation of phosphate uptake
ALFP_RS05660	COG2203	Gaf domain
ALFP_RS05660	COG4251	negative regulation of phosphorylation
ALFP_RS05660	COG5001	Diguanylate cyclase
ALFP_RS05660	COG3706	GGDEF domain
ALFP_RS05665	COG0659	secondary active sulfate transmembrane transporter activity
ALFP_RS05670	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ALFP_RS05675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALFP_RS05675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ALFP_RS05680	COG1643	Atp-dependent helicase
ALFP_RS05690	COG0438	transferase activity, transferring glycosyl groups
ALFP_RS05695	COG0726	polysaccharide deacetylase
ALFP_RS05710	COG0438	transferase activity, transferring glycosyl groups
ALFP_RS05735	COG1132	(ABC) transporter
ALFP_RS05790	COG2186	Transcriptional regulator
ALFP_RS05795	COG0277	FAD linked oxidase domain protein
ALFP_RS05800	COG0277	FAD linked oxidase domain protein
ALFP_RS05805	COG0247	lactate metabolic process
ALFP_RS05830	COG0628	permease
ALFP_RS05835	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALFP_RS05850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS05860	COG0697	spore germination
ALFP_RS05880	COG3094	Invasion gene expression up-regulator, SirB
ALFP_RS05890	COG0640	Transcriptional regulator
ALFP_RS05915	COG0659	secondary active sulfate transmembrane transporter activity
ALFP_RS05920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALFP_RS05930	COG2314	TM2 domain
ALFP_RS05935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ALFP_RS05940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ALFP_RS05945	COG0791	NLP P60 protein
ALFP_RS05965	COG1360	Flagellar Motor Protein
ALFP_RS05975	COG0835	chemotaxis
ALFP_RS05980	COG0840	transmembrane signaling receptor activity
ALFP_RS05985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALFP_RS05995	COG0745	RESPONSE REGULATOR receiver
ALFP_RS06000	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ALFP_RS06010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALFP_RS06020	COG3550	peptidyl-serine autophosphorylation
ALFP_RS06045	COG1815	bacterial-type flagellum-dependent cell motility
ALFP_RS06050	COG1558	bacterial-type flagellum-dependent cell motility
ALFP_RS06055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ALFP_RS06095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALFP_RS06120	COG2176	DNA-directed DNA polymerase activity
ALFP_RS06130	COG1987	bacterial-type flagellum assembly
ALFP_RS06145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALFP_RS06170	COG1157	protein secretion by the type III secretion system
ALFP_RS06185	COG1766	The M ring may be actively involved in energy transduction
ALFP_RS06190	COG1677	Flagellar hook-basal body complex protein FliE
ALFP_RS06195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALFP_RS06220	COG1334	flagellar protein FlaG
ALFP_RS06225	COG1191	sigma factor activity
ALFP_RS06280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALFP_RS06300	COG2733	membrane
ALFP_RS06305	COG0840	transmembrane signaling receptor activity
ALFP_RS06310	COG0840	transmembrane signaling receptor activity
ALFP_RS06335	COG2610	gluconate transmembrane transporter activity
ALFP_RS06350	COG0582	viral genome integration into host DNA
ALFP_RS06360	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS06390	COG1538	Outer membrane efflux protein
ALFP_RS06395	COG4521	taurine ABC transporter
ALFP_RS06400	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALFP_RS06405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS06415	COG0583	DNA-binding transcription factor activity
ALFP_RS06445	COG2824	Alkylphosphonate utilization operon protein PhnA
ALFP_RS06465	COG1113	amino acid transport
ALFP_RS06485	COG0583	DNA-binding transcription factor activity
ALFP_RS06490	COG3755	Protein conserved in bacteria
ALFP_RS06495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ALFP_RS06530	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALFP_RS06555	COG1278	Cold shock
ALFP_RS06560	COG0642	Histidine kinase
ALFP_RS06570	COG3278	Belongs to the heme-copper respiratory oxidase family
ALFP_RS06580	COG2863	cytochrome
ALFP_RS06585	COG3258	Cytochrome c
ALFP_RS06600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALFP_RS06605	COG4774	siderophore transport
ALFP_RS06640	COG0025	NhaP-type Na H and K H
ALFP_RS06655	COG1289	transmembrane transporter activity
ALFP_RS06660	COG2252	PERMEase
ALFP_RS06680	COG1999	signal sequence binding
ALFP_RS06690	COG0069	glutamate synthase activity
ALFP_RS06700	COG1846	Transcriptional regulator
ALFP_RS06710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALFP_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS06760	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ALFP_RS06760	COG3264	Mechanosensitive ion channel
ALFP_RS06765	COG3264	Mechanosensitive ion channel
ALFP_RS06765	COG1511	domain protein
ALFP_RS06770	COG0477	Major facilitator Superfamily
ALFP_RS06785	COG1396	sequence-specific DNA binding
ALFP_RS06790	COG3437	response regulator, receiver
ALFP_RS06795	COG2205	protein histidine kinase activity
ALFP_RS06795	COG2198	Histidine kinase
ALFP_RS06795	COG0784	Response regulator, receiver
ALFP_RS06800	COG2239	Acts as a magnesium transporter
ALFP_RS06810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALFP_RS06815	COG1490	D-aminoacyl-tRNA deacylase activity
ALFP_RS06830	COG0456	acetyltransferase
ALFP_RS06840	COG0501	Belongs to the peptidase M48B family
ALFP_RS06845	COG2814	Major facilitator Superfamily
ALFP_RS06910	COG2199	diguanylate cyclase activity
ALFP_RS06925	COG1522	sequence-specific DNA binding
ALFP_RS06930	COG0626	cystathionine gamma-synthase activity
ALFP_RS06940	COG0494	nUDIX hydrolase
ALFP_RS06945	COG2832	Protein of unknown function (DUF454)
ALFP_RS06955	COG0137	argininosuccinate synthase activity
ALFP_RS06960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ALFP_RS06965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALFP_RS06985	COG1609	Transcriptional regulator
ALFP_RS06995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ALFP_RS07005	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ALFP_RS07010	COG2205	protein histidine kinase activity
ALFP_RS07015	COG0745	RESPONSE REGULATOR receiver
ALFP_RS07020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALFP_RS07030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALFP_RS07035	COG0268	Binds directly to 16S ribosomal RNA
ALFP_RS07040	COG0728	peptidoglycan biosynthetic process
ALFP_RS07050	COG0563	adenylate kinase activity
ALFP_RS07055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ALFP_RS07060	COG2835	tetraacyldisaccharide 4'-kinase activity
ALFP_RS07070	COG0848	biopolymer transport protein
ALFP_RS07075	COG0811	peptide transport
ALFP_RS07080	COG1570	exodeoxyribonuclease VII activity
ALFP_RS07085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALFP_RS07095	COG0183	Belongs to the thiolase family
ALFP_RS07105	COG1278	Cold shock
ALFP_RS07110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALFP_RS07115	COG0542	response to heat
ALFP_RS07120	COG2995	paraquat-inducible protein a
ALFP_RS07125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALFP_RS07125	COG3008	intermembrane lipid transfer
ALFP_RS07145	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS07185	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ALFP_RS07190	COG0756	dUTP diphosphatase activity
ALFP_RS07200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALFP_RS07205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALFP_RS07210	COG0196	riboflavin kinase activity
ALFP_RS07215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ALFP_RS07220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALFP_RS07220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALFP_RS07230	COG0210	DNA helicase
ALFP_RS07285	COG0488	(ABC) transporter
ALFP_RS07290	COG2890	protein-(glutamine-N5) methyltransferase activity
ALFP_RS07295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALFP_RS07300	COG2171	N-acyltransferase activity
ALFP_RS07310	COG2207	Transcriptional regulator
ALFP_RS07320	COG0471	metal ion transport
ALFP_RS07320	COG3273	potassium ion transport
ALFP_RS07365	COG0789	Transcriptional regulator
ALFP_RS07380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS07385	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALFP_RS07390	COG0740	serine-type endopeptidase activity
ALFP_RS07400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALFP_RS07415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALFP_RS07425	COG0556	nucleotide-excision repair
ALFP_RS07430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALFP_RS07440	COG1104	cysteine desulfurase activity
ALFP_RS07450	COG0316	Belongs to the HesB IscA family
ALFP_RS07470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALFP_RS07475	COG4221	oxidoreductase activity
ALFP_RS07485	COG0840	transmembrane signaling receptor activity
ALFP_RS07490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALFP_RS07495	COG0697	spore germination
ALFP_RS07500	COG0385	Bile acid
ALFP_RS07510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ALFP_RS07525	COG1136	(ABC) transporter
ALFP_RS07530	COG0084	hydrolase, TatD family'
ALFP_RS07545	COG0613	PHP domain protein
ALFP_RS07555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALFP_RS07555	COG0047	phosphoribosylformylglycinamidine synthase activity
ALFP_RS07580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALFP_RS07580	COG0519	Catalyzes the synthesis of GMP from XMP
ALFP_RS07615	COG1360	Flagellar Motor Protein
ALFP_RS07645	COG2076	Multidrug Resistance protein
ALFP_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS07655	COG0583	DNA-binding transcription factor activity
ALFP_RS07670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALFP_RS07680	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS07690	COG2378	regulation of single-species biofilm formation
ALFP_RS07695	COG0523	cobalamin synthesis protein
ALFP_RS07700	COG1469	GTP cyclohydrolase I activity
ALFP_RS07705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALFP_RS07715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ALFP_RS07720	COG0735	belongs to the Fur family
ALFP_RS07725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALFP_RS07745	COG0745	RESPONSE REGULATOR receiver
ALFP_RS07760	COG0583	DNA-binding transcription factor activity
ALFP_RS07765	COG1289	transmembrane transporter activity
ALFP_RS07775	COG1566	PFAM secretion protein HlyD family protein
ALFP_RS07785	COG1942	4-Oxalocrotonate Tautomerase
ALFP_RS07800	COG3162	membrane
ALFP_RS07805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALFP_RS07815	COG2070	2-Nitropropane dioxygenase
ALFP_RS07840	COG1309	transcriptional regulator
ALFP_RS07855	COG0625	glutathione transferase activity
ALFP_RS07860	COG0583	DNA-binding transcription factor activity
ALFP_RS07880	COG0625	glutathione transferase activity
ALFP_RS07885	COG0740	serine-type endopeptidase activity
ALFP_RS07940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALFP_RS07950	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS07975	COG0640	Transcriptional regulator
ALFP_RS08000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALFP_RS08025	COG3485	protocatechuate 3,4-dioxygenase
ALFP_RS08035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALFP_RS08040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALFP_RS08050	COG3135	benzoate transporter
ALFP_RS08055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALFP_RS08060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ALFP_RS08070	COG4555	ABC transporter
ALFP_RS08080	COG2197	response regulator
ALFP_RS08085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALFP_RS08110	COG1846	Transcriptional regulator
ALFP_RS08115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS08120	COG2271	Major facilitator Superfamily
ALFP_RS08130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALFP_RS08140	COG0697	spore germination
ALFP_RS08170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALFP_RS08175	COG0667	Aldo Keto reductase
ALFP_RS08200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ALFP_RS08205	COG1335	isochorismatase
ALFP_RS08215	COG2135	peptidase activity
ALFP_RS08230	COG1272	protein, Hemolysin III
ALFP_RS08235	COG3422	double-strand break repair
ALFP_RS08255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS08260	COG0765	amino acid transport
ALFP_RS08265	COG0765	amino acid transport
ALFP_RS08270	COG1126	abc transporter atp-binding protein
ALFP_RS08325	COG2871	sodium ion transport
ALFP_RS08355	COG2814	Major facilitator Superfamily
ALFP_RS08360	COG1280	lysine exporter protein (LysE YggA)
ALFP_RS08380	COG0402	S-adenosylhomocysteine deaminase activity
ALFP_RS08405	COG0330	HflC and HflK could
ALFP_RS08410	COG1585	Membrane protein implicated in regulation of membrane protease activity
ALFP_RS08415	COG2226	methyltransferase
ALFP_RS08425	COG3042	response to heat
ALFP_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALFP_RS08450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALFP_RS08455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALFP_RS08470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALFP_RS08475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALFP_RS08505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALFP_RS08510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALFP_RS08515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALFP_RS08520	COG0072	phenylalanine-tRNA ligase activity
ALFP_RS08520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALFP_RS08535	COG2833	Protein of unknown function (DUF455)
ALFP_RS08545	COG5265	(ABC) transporter
ALFP_RS08550	COG1959	2 iron, 2 sulfur cluster binding
ALFP_RS08555	COG0719	Fe-S assembly protein
ALFP_RS08560	COG0396	ATPase activity
ALFP_RS08565	COG0719	Fe-S assembly protein
ALFP_RS08575	COG0822	iron-sulfur transferase activity
ALFP_RS08580	COG2151	metal-sulfur cluster biosynthetic enzyme
ALFP_RS08600	COG1538	Outer membrane efflux protein
ALFP_RS08610	COG2274	protein secretion by the type I secretion system
ALFP_RS08635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALFP_RS08640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALFP_RS08645	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALFP_RS08665	COG0747	negative chemotaxis
ALFP_RS08670	COG0601	transmembrane transport
ALFP_RS08675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALFP_RS08680	COG4172	Belongs to the ABC transporter superfamily
ALFP_RS08690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALFP_RS08730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALFP_RS08730	COG1017	nitric oxide dioxygenase activity
ALFP_RS08735	COG1959	2 iron, 2 sulfur cluster binding
ALFP_RS08820	COG4626	Terminase
ALFP_RS08820	COG1802	Transcriptional regulator
ALFP_RS08860	COG3728	DNA packaging
ALFP_RS08875	COG3566	protein conserved in bacteria
ALFP_RS09015	COG2135	peptidase activity
ALFP_RS09055	COG3048	D-serine ammonia-lyase activity
ALFP_RS09060	COG3258	Cytochrome c
ALFP_RS09075	COG3949	Membrane
ALFP_RS09085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALFP_RS09100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALFP_RS09105	COG0569	domain protein
ALFP_RS09110	COG1902	pentaerythritol trinitrate reductase activity
ALFP_RS09120	COG1610	YqeY-like protein
ALFP_RS09125	COG0587	DNA-directed DNA polymerase activity
ALFP_RS09160	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS09165	COG0583	DNA-binding transcription factor activity
ALFP_RS09170	COG1686	Belongs to the peptidase S11 family
ALFP_RS09185	COG1360	Flagellar Motor Protein
ALFP_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS09200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALFP_RS09205	COG4221	oxidoreductase activity
ALFP_RS09210	COG0307	riboflavin synthase, alpha
ALFP_RS09260	COG2233	PERMEase
ALFP_RS09265	COG0071	Belongs to the small heat shock protein (HSP20) family
ALFP_RS09270	COG1473	amidohydrolase
ALFP_RS09280	COG2814	Major facilitator Superfamily
ALFP_RS09310	COG2816	NAD+ diphosphatase activity
ALFP_RS09315	COG1561	YicC-like family, N-terminal region
ALFP_RS09330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ALFP_RS09335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALFP_RS09340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALFP_RS09345	COG0174	glutamine synthetase
ALFP_RS09350	COG2153	protein acetylation
ALFP_RS09370	COG3842	ATPase activity
ALFP_RS09375	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ALFP_RS09380	COG1840	ABC-type Fe3 transport system, periplasmic component
ALFP_RS09395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALFP_RS09410	COG0783	Belongs to the Dps family
ALFP_RS09420	COG3842	ATPase activity
ALFP_RS09425	COG0395	ABC-type sugar transport system, permease component
ALFP_RS09430	COG1175	transmembrane transport
ALFP_RS09435	COG1653	transport
ALFP_RS09450	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS09470	COG0625	glutathione transferase activity
ALFP_RS09480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALFP_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS09495	COG0114	fumarate hydratase activity
ALFP_RS09500	COG2133	pyrroloquinoline quinone binding
ALFP_RS09505	COG2226	methyltransferase
ALFP_RS09510	COG0589	response to stress
ALFP_RS09520	COG2207	Transcriptional regulator
ALFP_RS09525	COG0235	Class ii aldolase
ALFP_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS09540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS09545	COG2807	transmembrane transport
ALFP_RS09555	COG0583	DNA-binding transcription factor activity
ALFP_RS09585	COG0583	DNA-binding transcription factor activity
ALFP_RS09590	COG4974	Belongs to the 'phage' integrase family
ALFP_RS09600	COG2132	Multicopper oxidase
ALFP_RS09605	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ALFP_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS09645	COG3038	cytochrome b561
ALFP_RS09655	COG2353	YceI-like domain
ALFP_RS09660	COG1393	Belongs to the ArsC family
ALFP_RS09665	COG0625	glutathione transferase activity
ALFP_RS09685	COG0084	hydrolase, TatD family'
ALFP_RS09690	COG0470	DNA polymerase III
ALFP_RS09700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALFP_RS09720	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS09725	COG2914	Belongs to the UPF0125 (RnfH) family
ALFP_RS09730	COG2867	negative regulation of translational initiation
ALFP_RS09735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALFP_RS09740	COG1252	NADH dehydrogenase
ALFP_RS09765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALFP_RS09770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALFP_RS09775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALFP_RS09785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALFP_RS09790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALFP_RS09800	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALFP_RS09810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ALFP_RS09815	COG0575	Belongs to the CDS family
ALFP_RS09820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALFP_RS09825	COG0233	cytoplasmic translational termination
ALFP_RS09830	COG0528	UMP kinase activity
ALFP_RS09835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALFP_RS09840	COG0052	Belongs to the universal ribosomal protein uS2 family
ALFP_RS09845	COG0024	Methionine aminopeptidase
ALFP_RS09850	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ALFP_RS09875	COG1286	toxin biosynthetic process
ALFP_RS09885	COG0285	dihydrofolate synthase activity
ALFP_RS09890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALFP_RS09895	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALFP_RS09900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALFP_RS09915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALFP_RS09925	COG1999	signal sequence binding
ALFP_RS09930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALFP_RS09935	COG0640	Transcriptional regulator
ALFP_RS09955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALFP_RS09965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALFP_RS09970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALFP_RS09975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ALFP_RS10000	COG0183	Belongs to the thiolase family
ALFP_RS10010	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ALFP_RS10040	COG0194	GDP metabolic process
ALFP_RS10045	COG1758	RNA polymerase activity
ALFP_RS10050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALFP_RS10060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ALFP_RS10065	COG0739	heme binding
ALFP_RS10070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALFP_RS10075	COG0584	glycerophosphoryl diester phosphodiesterase
ALFP_RS10080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ALFP_RS10085	COG1187	pseudouridine synthase activity
ALFP_RS10090	COG3161	chorismate lyase activity
ALFP_RS10095	COG2814	Major facilitator Superfamily
ALFP_RS10100	COG0656	L-ascorbic acid biosynthetic process
ALFP_RS10110	COG0668	transmembrane transport
ALFP_RS10115	COG0165	Argininosuccinate lyase
ALFP_RS10120	COG1940	carbohydrate kinase activity
ALFP_RS10120	COG1846	Transcriptional regulator
ALFP_RS10130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS10140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALFP_RS10150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALFP_RS10155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALFP_RS10160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALFP_RS10165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALFP_RS10170	COG2252	PERMEase
ALFP_RS10175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALFP_RS10195	COG0488	(ABC) transporter
ALFP_RS10200	COG1619	proteins homologs of microcin C7 resistance protein MccF
ALFP_RS10210	COG1131	(ABC) transporter
ALFP_RS10215	COG0842	Transport permease protein
ALFP_RS10225	COG1666	GTP binding
ALFP_RS10230	COG0318	PFAM AMP-dependent synthetase and ligase
ALFP_RS10235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALFP_RS10240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALFP_RS10240	COG0519	Catalyzes the synthesis of GMP from XMP
ALFP_RS10255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALFP_RS10260	COG0135	phosphoribosylanthranilate isomerase activity
ALFP_RS10265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS10275	COG0101	tRNA pseudouridine synthase activity
ALFP_RS10285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ALFP_RS10310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ALFP_RS10320	COG4566	intracellular signal transduction
ALFP_RS10335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALFP_RS10340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ALFP_RS10350	COG1295	ribonuclease BN
ALFP_RS10360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALFP_RS10395	COG4964	Belongs to the GSP D family
ALFP_RS10440	COG2959	enzyme of heme biosynthesis
ALFP_RS10450	COG0181	hydroxymethylbilane synthase activity
ALFP_RS10455	COG0861	Integral membrane protein TerC family
ALFP_RS10460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALFP_RS10465	COG0045	succinate-CoA ligase (ADP-forming) activity
ALFP_RS10480	COG0583	DNA-binding transcription factor activity
ALFP_RS10485	COG2137	regulation of response to DNA damage stimulus
ALFP_RS10490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALFP_RS10505	COG0477	Major facilitator Superfamily
ALFP_RS10520	COG0318	PFAM AMP-dependent synthetase and ligase
ALFP_RS10525	COG1024	Enoyl-CoA hydratase
ALFP_RS10530	COG3162	membrane
ALFP_RS10545	COG0540	Belongs to the ATCase OTCase family
ALFP_RS10560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALFP_RS10575	COG2070	2-Nitropropane dioxygenase
ALFP_RS10580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALFP_RS10585	COG2111	Na H antiporter
ALFP_RS10585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALFP_RS10590	COG1006	Multisubunit Na H antiporter MnhC subunit
ALFP_RS10595	COG0651	ATP synthesis coupled electron transport
ALFP_RS10605	COG2212	antiporter activity
ALFP_RS10620	COG0477	Major facilitator Superfamily
ALFP_RS10645	COG3158	transport of potassium into the cell
ALFP_RS10650	COG0642	Histidine kinase
ALFP_RS10675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALFP_RS10680	COG4208	sulfate ABC transporter
ALFP_RS10685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ALFP_RS10690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALFP_RS10705	COG1278	Cold shock
ALFP_RS10720	COG1648	precorrin-2 dehydrogenase activity
ALFP_RS10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALFP_RS10725	COG2010	Cytochrome c
ALFP_RS10750	COG0535	radical SAM domain protein
ALFP_RS10760	COG1648	precorrin-2 dehydrogenase activity
ALFP_RS10760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALFP_RS10770	COG2010	Cytochrome c
ALFP_RS10775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS10780	COG0626	cystathionine gamma-synthase activity
ALFP_RS10785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALFP_RS10790	COG0557	exoribonuclease II activity
ALFP_RS10810	COG0765	amino acid transport
ALFP_RS10815	COG0765	amino acid transport
ALFP_RS10820	COG1126	abc transporter atp-binding protein
ALFP_RS10835	COG1850	ribulose-bisphosphate carboxylase activity
ALFP_RS10855	COG2375	cellular response to nickel ion
ALFP_RS10870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS10885	COG0583	DNA-binding transcription factor activity
ALFP_RS10890	COG3842	ATPase activity
ALFP_RS10895	COG1175	transmembrane transport
ALFP_RS10900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALFP_RS10905	COG1840	ABC-type Fe3 transport system, periplasmic component
ALFP_RS10925	COG0412	Dienelactone hydrolase
ALFP_RS10930	COG3530	Putative quorum-sensing-regulated virulence factor
ALFP_RS10935	COG0625	glutathione transferase activity
ALFP_RS10940	COG1741	Belongs to the pirin family
ALFP_RS10950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFP_RS10955	COG2814	Major facilitator Superfamily
ALFP_RS10960	COG2807	transmembrane transport
ALFP_RS10965	COG2207	Transcriptional regulator
ALFP_RS10970	COG3135	benzoate transporter
ALFP_RS10995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALFP_RS11005	COG0402	S-adenosylhomocysteine deaminase activity
ALFP_RS11015	COG0745	RESPONSE REGULATOR receiver
ALFP_RS11020	COG2205	protein histidine kinase activity
ALFP_RS11035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALFP_RS11040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ALFP_RS11045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALFP_RS11055	COG0330	HflC and HflK could
ALFP_RS11060	COG0330	HflC and HflK could
ALFP_RS11065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALFP_RS11070	COG1923	regulation of RNA biosynthetic process
ALFP_RS11080	COG1160	GTP binding
ALFP_RS11085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALFP_RS11090	COG2976	Protein conserved in bacteria
ALFP_RS11095	COG0124	histidyl-tRNA synthetase
ALFP_RS11110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALFP_RS11115	COG0105	UTP biosynthetic process
ALFP_RS11125	COG0336	Belongs to the RNA methyltransferase TrmD family
ALFP_RS11135	COG0228	four-way junction DNA binding
ALFP_RS11140	COG0425	Belongs to the sulfur carrier protein TusA family
ALFP_RS11145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALFP_RS11160	COG2351	hydroxyisourate hydrolase activity
ALFP_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS11220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALFP_RS11225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALFP_RS11250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALFP_RS11255	COG0601	transmembrane transport
ALFP_RS11285	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ALFP_RS11290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALFP_RS11295	COG0542	response to heat
ALFP_RS11300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALFP_RS11315	COG0348	domain, Protein
ALFP_RS11335	COG3278	Belongs to the heme-copper respiratory oxidase family
ALFP_RS11345	COG2217	Heavy metal translocating P-type atpase
ALFP_RS11350	COG2224	Isocitrate lyase
ALFP_RS11355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALFP_RS11355	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALFP_RS11375	COG1472	Belongs to the glycosyl hydrolase 3 family
ALFP_RS11380	COG0736	holo-[acyl-carrier-protein] synthase activity
ALFP_RS11390	COG2050	protein possibly involved in aromatic compounds catabolism
ALFP_RS11395	COG1024	Enoyl-CoA hydratase
ALFP_RS11400	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS11405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALFP_RS11410	COG2151	metal-sulfur cluster biosynthetic enzyme
ALFP_RS11415	COG3396	Phenylacetate-CoA oxygenase
ALFP_RS11420	COG3460	Phenylacetate-CoA oxygenase
ALFP_RS11425	COG3396	Phenylacetate-CoA oxygenase
ALFP_RS11430	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALFP_RS11435	COG0501	Belongs to the peptidase M48B family
ALFP_RS11440	COG1162	GTPase activity
ALFP_RS11450	COG0335	large ribosomal subunit rRNA binding
ALFP_RS11470	COG0450	alkyl hydroperoxide reductase
ALFP_RS11475	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS11495	COG2951	lytic endotransglycosylase activity
ALFP_RS11505	COG1596	polysaccharide export
ALFP_RS11505	COG1555	photosystem II stabilization
ALFP_RS11510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALFP_RS11515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ALFP_RS11520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ALFP_RS11540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ALFP_RS11545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALFP_RS11550	COG0287	Prephenate dehydrogenase
ALFP_RS11560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALFP_RS11575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALFP_RS11595	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALFP_RS11605	COG4771	TonB-dependent receptor
ALFP_RS11620	COG0753	catalase activity
ALFP_RS11630	COG4335	DNA alkylation repair
ALFP_RS11640	COG0436	Aminotransferase
ALFP_RS11650	COG0251	oxidation-reduction process
ALFP_RS11655	COG1309	transcriptional regulator
ALFP_RS11710	COG0625	glutathione transferase activity
ALFP_RS11740	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ALFP_RS11785	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ALFP_RS11790	COG1280	lysine exporter protein (LysE YggA)
ALFP_RS11810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALFP_RS11820	COG5002	protein histidine kinase activity
ALFP_RS11830	COG2046	Belongs to the sulfate adenylyltransferase family
ALFP_RS11835	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALFP_RS11840	COG0642	Histidine kinase
ALFP_RS11850	COG0840	transmembrane signaling receptor activity
ALFP_RS11855	COG2119	membrane
ALFP_RS11870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ALFP_RS11875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALFP_RS11890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALFP_RS11895	COG2321	neutral zinc metallopeptidase
ALFP_RS11910	COG2175	clavaminate synthase activity
ALFP_RS11915	COG1846	Transcriptional regulator
ALFP_RS11925	COG0347	Belongs to the P(II) protein family
ALFP_RS11930	COG0004	ammonium transporteR
ALFP_RS11935	COG3909	cytochrome
ALFP_RS11945	COG0625	glutathione transferase activity
ALFP_RS11955	COG0657	acetylesterase activity
ALFP_RS11960	COG0730	response to heat
ALFP_RS11965	COG0482	sulfurtransferase activity
ALFP_RS11970	COG0277	FAD linked oxidase domain protein
ALFP_RS11975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALFP_RS11980	COG2879	small protein
ALFP_RS11985	COG1966	Carbon starvation protein
ALFP_RS11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS11995	COG0765	amino acid transport
ALFP_RS12000	COG0765	amino acid transport
ALFP_RS12005	COG1126	abc transporter atp-binding protein
ALFP_RS12010	COG0028	Belongs to the TPP enzyme family
ALFP_RS12015	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS12020	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ALFP_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS12030	COG0596	Alpha beta hydrolase
ALFP_RS12030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALFP_RS12030	COG2226	methyltransferase
ALFP_RS12035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS12040	COG1116	anion transmembrane transporter activity
ALFP_RS12055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS12070	COG5285	phytanoyl-CoA dioxygenase
ALFP_RS12075	COG0662	Cupin 2, conserved barrel domain protein
ALFP_RS12085	COG0456	acetyltransferase
ALFP_RS12090	COG1846	Transcriptional regulator
ALFP_RS12100	COG0312	modulator of DNA gyrase
ALFP_RS12115	COG0308	aminopeptidase N
ALFP_RS12120	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALFP_RS12135	COG0473	3-isopropylmalate dehydrogenase activity
ALFP_RS12145	COG0433	COG0433 Predicted ATPase
ALFP_RS12150	COG0217	transcriptional regulatory protein
ALFP_RS12155	COG0151	Belongs to the GarS family
ALFP_RS12165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALFP_RS12170	COG0799	negative regulation of ribosome biogenesis
ALFP_RS12175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALFP_RS12180	COG0424	maF-like protein
ALFP_RS12200	COG0023	Translation Initiation Factor
ALFP_RS12210	COG2084	Dehydrogenase
ALFP_RS12215	COG0625	glutathione transferase activity
ALFP_RS12220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALFP_RS12225	COG1047	Peptidyl-prolyl cis-trans
ALFP_RS12230	COG2003	Belongs to the UPF0758 family
ALFP_RS12235	COG1737	Transcriptional regulator
ALFP_RS12240	COG0477	Major facilitator Superfamily
ALFP_RS12250	COG2271	Major facilitator Superfamily
ALFP_RS12265	COG0534	Mate efflux family protein
ALFP_RS12270	COG4175	Glycine betaine
ALFP_RS12275	COG4176	ABC-type proline glycine betaine transport system permease component
ALFP_RS12285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALFP_RS12295	COG2814	Major facilitator Superfamily
ALFP_RS12300	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALFP_RS12305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALFP_RS12310	COG0495	leucyl-tRNA aminoacylation
ALFP_RS12320	COG1466	dna polymerase III delta subunit
ALFP_RS12325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALFP_RS12330	COG1981	membrane
ALFP_RS12345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ALFP_RS12355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALFP_RS12360	COG0148	phosphopyruvate hydratase activity
ALFP_RS12370	COG2814	Major facilitator Superfamily
ALFP_RS12385	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALFP_RS12395	COG0504	CTP synthase activity
ALFP_RS12430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALFP_RS12440	COG0791	NLP P60 protein
ALFP_RS12450	COG0583	DNA-binding transcription factor activity
ALFP_RS12460	COG0583	DNA-binding transcription factor activity
ALFP_RS12470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALFP_RS12485	COG1045	serine acetyltransferase
ALFP_RS12500	COG1381	Involved in DNA repair and RecF pathway recombination
ALFP_RS12505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALFP_RS12510	COG0571	ribonuclease III activity
ALFP_RS12525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALFP_RS12550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALFP_RS12555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALFP_RS12560	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS12565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ALFP_RS12570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALFP_RS12580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALFP_RS12585	COG1399	metal-binding, possibly nucleic acid-binding protein
ALFP_RS12590	COG0424	maF-like protein
ALFP_RS12600	COG3023	N-Acetylmuramoyl-L-alanine amidase
ALFP_RS12605	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ALFP_RS12610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALFP_RS12615	COG0546	phosphoglycolate phosphatase activity
ALFP_RS12620	COG0564	pseudouridine synthase activity
ALFP_RS12625	COG1530	ribonuclease E activity
ALFP_RS12630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALFP_RS12635	COG0159	tryptophan synthase activity
ALFP_RS12640	COG0133	tryptophan synthase activity
ALFP_RS12645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALFP_RS12655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALFP_RS12660	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALFP_RS12670	COG2878	Part of a membrane complex involved in electron transport
ALFP_RS12675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALFP_RS12680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ALFP_RS12685	COG3047	cAMP biosynthetic process
ALFP_RS12710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALFP_RS12715	COG2917	probably involved in intracellular septation
ALFP_RS12725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALFP_RS12730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALFP_RS12740	COG1196	nuclear chromosome segregation
ALFP_RS12750	COG1573	uracil-dna glycosylase
ALFP_RS12755	COG1214	PFAM Peptidase M22, glycoprotease
ALFP_RS12770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALFP_RS12775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALFP_RS12780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALFP_RS12785	COG0560	Phosphoserine phosphatase
ALFP_RS12800	COG1007	ATP synthesis coupled electron transport
ALFP_RS12815	COG0713	ATP synthesis coupled electron transport
ALFP_RS12825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALFP_RS12830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ALFP_RS12835	COG1034	ATP synthesis coupled electron transport
ALFP_RS12850	COG0649	NAD binding
ALFP_RS12855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALFP_RS12860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALFP_RS12865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALFP_RS12870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS12885	COG0149	triose-phosphate isomerase activity
ALFP_RS12890	COG0604	alcohol dehydrogenase
ALFP_RS12910	COG1185	polyribonucleotide nucleotidyltransferase activity
ALFP_RS12915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALFP_RS12920	COG1183	phosphatidylcholine synthase activity
ALFP_RS12925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALFP_RS12930	COG0440	acetolactate synthase activity
ALFP_RS12935	COG0028	Belongs to the TPP enzyme family
ALFP_RS12940	COG1289	transmembrane transporter activity
ALFP_RS12945	COG3022	response to hydroperoxide
ALFP_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS12975	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALFP_RS12980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALFP_RS12985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALFP_RS12990	COG1674	ftsk spoiiie
ALFP_RS12995	COG0492	ferredoxin-NADP+ reductase activity
ALFP_RS13015	COG0477	Major facilitator Superfamily
ALFP_RS13035	COG2272	Belongs to the type-B carboxylesterase lipase family
ALFP_RS13040	COG1960	acyl-CoA dehydrogenase activity
ALFP_RS13065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALFP_RS13085	COG2204	response regulator
ALFP_RS13125	COG4964	Belongs to the GSP D family
ALFP_RS13185	COG0612	Peptidase, M16
ALFP_RS13190	COG0484	heat shock protein binding
ALFP_RS13195	COG0443	Heat shock 70 kDa protein
ALFP_RS13200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALFP_RS13205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALFP_RS13210	COG1420	regulation of RNA biosynthetic process
ALFP_RS13220	COG0497	DNA recombination
ALFP_RS13225	COG0735	belongs to the Fur family
ALFP_RS13230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALFP_RS13235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALFP_RS13260	COG0477	Major facilitator Superfamily
ALFP_RS13270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALFP_RS13305	COG1538	Outer membrane efflux protein
ALFP_RS13335	COG2814	Major facilitator Superfamily
ALFP_RS13350	COG2819	hydrolase of the alpha beta superfamily
ALFP_RS13370	COG1454	alcohol dehydrogenase
ALFP_RS13380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ALFP_RS13405	COG1414	Transcriptional regulator
ALFP_RS13410	COG0513	Belongs to the DEAD box helicase family
ALFP_RS13415	COG0583	DNA-binding transcription factor activity
ALFP_RS13420	COG4638	Rieske (2fe-2S)
ALFP_RS13425	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ALFP_RS13440	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALFP_RS13455	COG3971	2-oxopent-4-enoate hydratase activity
ALFP_RS13460	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ALFP_RS13465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALFP_RS13470	COG2814	Major facilitator Superfamily
ALFP_RS13485	COG0154	amidase activity
ALFP_RS13490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS13495	COG2814	Major facilitator Superfamily
ALFP_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS13530	COG0842	Transport permease protein
ALFP_RS13535	COG0842	Transport permease protein
ALFP_RS13535	COG1129	ABC transporter
ALFP_RS13540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALFP_RS13550	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALFP_RS13560	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ALFP_RS13565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ALFP_RS13570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALFP_RS13585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALFP_RS13600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALFP_RS13605	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ALFP_RS13615	COG0789	Transcriptional regulator
ALFP_RS13630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALFP_RS13675	COG3278	Belongs to the heme-copper respiratory oxidase family
ALFP_RS13680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS13700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ALFP_RS13750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ALFP_RS13815	COG0517	IMP dehydrogenase activity
ALFP_RS13815	COG0516	GMP reductase activity
ALFP_RS13830	COG1027	Aspartate ammonia-lyase
ALFP_RS13835	COG1846	Transcriptional regulator
ALFP_RS13850	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALFP_RS13855	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALFP_RS13875	COG1414	Transcriptional regulator
ALFP_RS13895	COG0513	Belongs to the DEAD box helicase family
ALFP_RS13915	COG0429	hydrolase of the alpha beta-hydrolase fold
ALFP_RS13940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALFP_RS13950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ALFP_RS13960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALFP_RS13965	COG0632	four-way junction helicase activity
ALFP_RS13975	COG2255	four-way junction helicase activity
ALFP_RS13985	COG0418	dihydroorotase activity
ALFP_RS13995	COG0415	Belongs to the DNA photolyase family
ALFP_RS14055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALFP_RS14060	COG4654	Cytochrome c, class I
ALFP_RS14095	COG1177	transmembrane transport
ALFP_RS14100	COG3842	ATPase activity
ALFP_RS14105	COG1840	ABC-type Fe3 transport system, periplasmic component
ALFP_RS14110	COG2084	Dehydrogenase
ALFP_RS14125	COG0494	nUDIX hydrolase
ALFP_RS14130	COG0442	prolyl-tRNA aminoacylation
ALFP_RS14135	COG0824	Thioesterase
ALFP_RS14140	COG0811	peptide transport
ALFP_RS14155	COG0823	Involved in the tonB-independent uptake of proteins
ALFP_RS14170	COG0596	Alpha beta hydrolase
ALFP_RS14195	COG1079	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS14200	COG4603	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS14205	COG3845	ABC transporter
ALFP_RS14225	COG0427	acetyl-CoA hydrolase
ALFP_RS14230	COG0583	DNA-binding transcription factor activity
ALFP_RS14235	COG3634	alkyl hydroperoxide reductase activity
ALFP_RS14250	COG0697	spore germination
ALFP_RS14255	COG0175	sulfate reduction
ALFP_RS14265	COG2895	sulfate adenylyltransferase (ATP) activity
ALFP_RS14275	COG1012	belongs to the aldehyde dehydrogenase family
ALFP_RS14280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALFP_RS14285	COG5383	Protein conserved in bacteria
ALFP_RS14295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALFP_RS14310	COG0583	DNA-binding transcription factor activity
ALFP_RS14315	COG1741	Belongs to the pirin family
ALFP_RS14325	COG3706	GGDEF domain
ALFP_RS14330	COG0154	amidase activity
ALFP_RS14345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALFP_RS14355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALFP_RS14360	COG0284	orotidine-5'-phosphate decarboxylase activity
ALFP_RS14375	COG1414	Transcriptional regulator
ALFP_RS14385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALFP_RS14395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALFP_RS14400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALFP_RS14425	COG0742	ribosomal rna small subunit methyltransferase
ALFP_RS14430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALFP_RS14435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALFP_RS14465	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ALFP_RS14480	COG1335	isochorismatase
ALFP_RS14485	COG2309	aminopeptidase activity
ALFP_RS14490	COG0596	Alpha beta hydrolase
ALFP_RS14495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALFP_RS14495	COG2010	Cytochrome c
ALFP_RS14500	COG2080	2 iron, 2 sulfur cluster binding
ALFP_RS14505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALFP_RS14505	COG2010	Cytochrome c
ALFP_RS14515	COG0410	ABC transporter
ALFP_RS14520	COG0411	ABC transporter
ALFP_RS14545	COG3706	GGDEF domain
ALFP_RS14560	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS14575	COG1234	tRNA 3'-trailer cleavage
ALFP_RS14580	COG2188	Transcriptional regulator
ALFP_RS14590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALFP_RS14600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALFP_RS14600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALFP_RS14605	COG3608	succinylglutamate desuccinylase aspartoacylase
ALFP_RS14605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ALFP_RS14610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALFP_RS14620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALFP_RS14650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS14680	COG1335	isochorismatase
ALFP_RS14685	COG2309	aminopeptidase activity
ALFP_RS14690	COG0596	Alpha beta hydrolase
ALFP_RS14705	COG1120	ATPase activity
ALFP_RS14710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALFP_RS14720	COG4206	TonB-dependent receptor
ALFP_RS14725	COG2031	fatty acid transporter
ALFP_RS14730	COG0583	DNA-binding transcription factor activity
ALFP_RS14735	COG0402	S-adenosylhomocysteine deaminase activity
ALFP_RS14740	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS14755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALFP_RS14760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALFP_RS14765	COG0328	RNA-DNA hybrid ribonuclease activity
ALFP_RS14770	COG2226	methyltransferase
ALFP_RS14775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALFP_RS14780	COG0741	lytic transglycosylase activity
ALFP_RS14780	COG1388	LysM domain
ALFP_RS14800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ALFP_RS14825	COG2204	response regulator
ALFP_RS14830	COG4191	Histidine kinase
ALFP_RS14835	COG1301	dicarboxylic acid transport
ALFP_RS14845	COG1054	Belongs to the UPF0176 family
ALFP_RS14870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ALFP_RS14875	COG2204	response regulator
ALFP_RS14890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ALFP_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS14910	COG1877	trehalose-phosphatase activity
ALFP_RS14945	COG0604	alcohol dehydrogenase
ALFP_RS14955	COG1024	Enoyl-CoA hydratase
ALFP_RS14975	COG1902	pentaerythritol trinitrate reductase activity
ALFP_RS14990	COG1454	alcohol dehydrogenase
ALFP_RS15010	COG0583	DNA-binding transcription factor activity
ALFP_RS15035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS15050	COG1393	Belongs to the ArsC family
ALFP_RS15055	COG0431	NADPH-dependent FMN reductase
ALFP_RS15060	COG0745	RESPONSE REGULATOR receiver
ALFP_RS15065	COG0642	Histidine kinase
ALFP_RS15145	COG2948	multi-organism process
ALFP_RS15180	COG0433	COG0433 Predicted ATPase
ALFP_RS15250	COG0582	viral genome integration into host DNA
ALFP_RS15260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALFP_RS15260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALFP_RS15265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALFP_RS15270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALFP_RS15275	COG1881	PFAM PEBP family protein
ALFP_RS15280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALFP_RS15285	COG0739	heme binding
ALFP_RS15290	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ALFP_RS15295	COG0316	Belongs to the HesB IscA family
ALFP_RS15305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALFP_RS15310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALFP_RS15315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALFP_RS15320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS15325	COG0312	modulator of DNA gyrase
ALFP_RS15330	COG3028	Belongs to the UPF0307 family
ALFP_RS15355	COG4566	intracellular signal transduction
ALFP_RS15360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALFP_RS15370	COG0402	S-adenosylhomocysteine deaminase activity
ALFP_RS15375	COG2233	PERMEase
ALFP_RS15380	COG2945	thiolester hydrolase activity
ALFP_RS15380	COG0596	Alpha beta hydrolase
ALFP_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS15400	COG0583	DNA-binding transcription factor activity
ALFP_RS15405	COG4681	YaeQ
ALFP_RS15430	COG0762	integral membrane protein
ALFP_RS15435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ALFP_RS15445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALFP_RS15460	COG0439	Biotin carboxylase
ALFP_RS15465	COG0511	ligase activity, forming carbon-carbon bonds
ALFP_RS15470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALFP_RS15480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALFP_RS15485	COG3150	esterase
ALFP_RS15500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALFP_RS15505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALFP_RS15515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALFP_RS15565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALFP_RS15575	COG3237	CsbD-like
ALFP_RS15580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALFP_RS15585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ALFP_RS15590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALFP_RS15595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALFP_RS15620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALFP_RS15635	COG1126	abc transporter atp-binding protein
ALFP_RS15640	COG0765	amino acid transport
ALFP_RS15645	COG4597	amino acid ABC transporter
ALFP_RS15650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALFP_RS15655	COG2884	Cell division ATP-binding protein ftsE
ALFP_RS15660	COG2177	Part of the ABC transporter FtsEX involved in
ALFP_RS15670	COG0772	Belongs to the SEDS family
ALFP_RS15675	COG0768	penicillin binding
ALFP_RS15685	COG1792	Involved in formation and maintenance of cell shape
ALFP_RS15690	COG1077	Cell shape determining protein MreB Mrl
ALFP_RS15695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALFP_RS15700	COG0154	amidase activity
ALFP_RS15705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALFP_RS15710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALFP_RS15715	COG0583	DNA-binding transcription factor activity
ALFP_RS15720	COG2259	Doxx family
ALFP_RS15725	COG3384	dioxygenase
ALFP_RS15735	COG3245	cytochrome
ALFP_RS15750	COG3604	Transcriptional regulator
ALFP_RS15765	COG0786	glutamate:sodium symporter activity
ALFP_RS15770	COG0142	geranyltranstransferase activity
ALFP_RS15780	COG0494	nUDIX hydrolase
ALFP_RS15785	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALFP_RS15810	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ALFP_RS15815	COG0237	dephospho-CoA kinase activity
ALFP_RS15830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALFP_RS15835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ALFP_RS15845	COG0477	Major facilitator Superfamily
ALFP_RS15860	COG4206	TonB-dependent receptor
ALFP_RS15865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALFP_RS15880	COG1595	DNA-templated transcription, initiation
ALFP_RS15890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALFP_RS15910	COG0598	Magnesium transport protein CorA
ALFP_RS15925	COG2022	thiamine diphosphate biosynthetic process
ALFP_RS15930	COG0351	phosphomethylpyrimidine kinase
ALFP_RS15935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALFP_RS15940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALFP_RS15945	COG1538	Outer membrane efflux protein
ALFP_RS15950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALFP_RS15960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALFP_RS15975	COG2226	methyltransferase
ALFP_RS15980	COG0745	RESPONSE REGULATOR receiver
ALFP_RS15995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALFP_RS16000	COG1984	allophanate hydrolase subunit 2
ALFP_RS16005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALFP_RS16010	COG1238	metal cluster binding
ALFP_RS16035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ALFP_RS16040	COG4988	ABC transporter
ALFP_RS16050	COG1294	oxidase, subunit
ALFP_RS16055	COG1271	oxidase subunit
ALFP_RS16070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALFP_RS16085	COG1137	ATPase activity
ALFP_RS16095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALFP_RS16100	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ALFP_RS16105	COG1660	Displays ATPase and GTPase activities
ALFP_RS16115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALFP_RS16120	COG0792	nuclease activity
ALFP_RS16125	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ALFP_RS16140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALFP_RS16160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALFP_RS16165	COG0793	Belongs to the peptidase S41A family
ALFP_RS16175	COG0588	phosphoglycerate mutase activity
ALFP_RS16180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALFP_RS16190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ALFP_RS16195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALFP_RS16200	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS16205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALFP_RS16210	COG1040	competence protein
ALFP_RS16215	COG2226	methyltransferase
ALFP_RS16220	COG4771	TonB-dependent receptor
ALFP_RS16225	COG0745	RESPONSE REGULATOR receiver
ALFP_RS16240	COG2204	response regulator
ALFP_RS16260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALFP_RS16270	COG3473	Maleate cis-trans isomerase
ALFP_RS16285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALFP_RS16315	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ALFP_RS16315	COG0662	Cupin 2, conserved barrel domain protein
ALFP_RS16320	COG1215	transferase activity, transferring glycosyl groups
ALFP_RS16330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALFP_RS16345	COG1088	dTDP-glucose 4,6-dehydratase activity
ALFP_RS16350	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ALFP_RS16365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALFP_RS16375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALFP_RS16380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALFP_RS16385	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALFP_RS16400	COG0356	it plays a direct role in the translocation of protons across the membrane
ALFP_RS16410	COG1024	Enoyl-CoA hydratase
ALFP_RS16425	COG0037	tRNA processing
ALFP_RS16430	COG0163	prenyltransferase activity
ALFP_RS16435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ALFP_RS16440	COG2890	protein-(glutamine-N5) methyltransferase activity
ALFP_RS16480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALFP_RS16485	COG2264	protein methyltransferase activity
ALFP_RS16490	COG4773	Receptor
ALFP_RS16510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALFP_RS16535	COG3180	Ammonia monooxygenase
ALFP_RS16555	COG5002	protein histidine kinase activity
ALFP_RS16570	COG0477	Major facilitator Superfamily
ALFP_RS16575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFP_RS16595	COG1116	anion transmembrane transporter activity
ALFP_RS16620	COG0243	molybdopterin cofactor binding
ALFP_RS16620	COG3383	formate dehydrogenase (NAD+) activity
ALFP_RS16625	COG3383	formate dehydrogenase (NAD+) activity
ALFP_RS16625	COG0243	molybdopterin cofactor binding
ALFP_RS16630	COG0437	4 iron, 4 sulfur cluster binding
ALFP_RS16635	COG2864	formate dehydrogenase
ALFP_RS16645	COG1921	L-seryl-tRNASec selenium transferase activity
ALFP_RS16650	COG3276	selenocysteine insertion sequence binding
ALFP_RS16660	COG1476	TRANSCRIPTIONal
ALFP_RS16675	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS16695	COG0709	Synthesizes selenophosphate from selenide and ATP
ALFP_RS16710	COG0583	DNA-binding transcription factor activity
ALFP_RS16715	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ALFP_RS16720	COG0348	domain, Protein
ALFP_RS16720	COG3901	Regulator of nitric oxide reductase transcription
ALFP_RS16725	COG4263	nitrous-oxide reductase activity
ALFP_RS16740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ALFP_RS16755	COG0166	Belongs to the GPI family
ALFP_RS16780	COG1215	transferase activity, transferring glycosyl groups
ALFP_RS16820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALFP_RS16850	COG0156	8-amino-7-oxononanoate synthase activity
ALFP_RS16855	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS16855	COG0604	alcohol dehydrogenase
ALFP_RS16855	COG3321	synthase
ALFP_RS16860	COG2233	PERMEase
ALFP_RS16865	COG0697	spore germination
ALFP_RS16870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS16875	COG0697	spore germination
ALFP_RS16895	COG2885	chlorophyll binding
ALFP_RS16990	COG0183	Belongs to the thiolase family
ALFP_RS16995	COG1024	Enoyl-CoA hydratase
ALFP_RS16995	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALFP_RS17010	COG1127	ABC transporter
ALFP_RS17015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALFP_RS17020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALFP_RS17035	COG1131	(ABC) transporter
ALFP_RS17040	COG0842	Transport permease protein
ALFP_RS17050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALFP_RS17060	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALFP_RS17065	COG0131	Imidazoleglycerol-phosphate dehydratase
ALFP_RS17075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALFP_RS17080	COG0107	imidazoleglycerol-phosphate synthase activity
ALFP_RS17090	COG0140	phosphoribosyl-ATP diphosphatase activity
ALFP_RS17095	COG0537	adenosine 5'-monophosphoramidase activity
ALFP_RS17100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALFP_RS17105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALFP_RS17115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALFP_RS17125	COG1970	mechanosensitive ion channel activity
ALFP_RS17130	COG0723	plastoquinol--plastocyanin reductase activity
ALFP_RS17135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALFP_RS17140	COG2857	Cytochrome c1
ALFP_RS17145	COG0625	glutathione transferase activity
ALFP_RS17150	COG2969	positive regulation of protein catabolic process
ALFP_RS17155	COG4208	sulfate ABC transporter
ALFP_RS17160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ALFP_RS17165	COG4150	thiosulfate binding
ALFP_RS17205	COG4948	Mandelate Racemase Muconate Lactonizing
ALFP_RS17215	COG4638	Rieske (2fe-2S)
ALFP_RS17230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALFP_RS17250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALFP_RS17255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALFP_RS17270	COG0129	dihydroxy-acid dehydratase activity
ALFP_RS17275	COG1802	Transcriptional regulator
ALFP_RS17280	COG1522	sequence-specific DNA binding
ALFP_RS17285	COG3483	tryptophan 2,3-dioxygenase activity
ALFP_RS17305	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALFP_RS17310	COG0656	L-ascorbic acid biosynthetic process
ALFP_RS17320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALFP_RS17330	COG2226	methyltransferase
ALFP_RS17340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALFP_RS17355	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ALFP_RS17360	COG0583	DNA-binding transcription factor activity
ALFP_RS17365	COG0477	Major facilitator Superfamily
ALFP_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
ALFP_RS17380	COG1335	isochorismatase
ALFP_RS17400	COG2823	Periplasmic or secreted lipoprotein
ALFP_RS17410	COG3284	Transcriptional regulator
ALFP_RS17445	COG1595	DNA-templated transcription, initiation
ALFP_RS17455	COG1522	sequence-specific DNA binding
ALFP_RS17465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALFP_RS17485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALFP_RS17520	COG0109	protoheme IX farnesyltransferase activity
ALFP_RS17540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALFP_RS17560	COG3568	Endonuclease Exonuclease Phosphatase
ALFP_RS17565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALFP_RS17590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALFP_RS17600	COG1228	amidohydrolase
ALFP_RS17610	COG2986	histidine ammonia-lyase
ALFP_RS17615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ALFP_RS17645	COG2814	Major facilitator Superfamily
ALFP_RS17655	COG0789	Transcriptional regulator
ALFP_RS17685	COG0625	glutathione transferase activity
ALFP_RS17715	COG2365	Tyrosine phosphatase family
ALFP_RS17720	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALFP_RS17740	COG2423	ornithine cyclodeaminase activity
ALFP_RS17790	COG3069	C4-dicarboxylate transmembrane transporter activity
ALFP_RS17800	COG1802	Transcriptional regulator
ALFP_RS17810	COG2814	Major facilitator Superfamily
ALFP_RS17825	COG2814	Major facilitator Superfamily
ALFP_RS17830	COG0251	oxidation-reduction process
ALFP_RS17835	COG3181	Tripartite tricarboxylate transporter family receptor
ALFP_RS17840	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALFP_RS17845	COG2186	Transcriptional regulator
ALFP_RS17855	COG2814	Major facilitator Superfamily
ALFP_RS17865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ALFP_RS17870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALFP_RS17875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALFP_RS17895	COG5002	protein histidine kinase activity
ALFP_RS17895	COG5001	Diguanylate cyclase
ALFP_RS17905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALFP_RS17910	COG1333	cytochrome c biogenesis protein
ALFP_RS17920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALFP_RS17925	COG0113	porphobilinogen synthase activity
ALFP_RS17930	COG4232	protein-disulfide reductase activity
ALFP_RS17950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALFP_RS17955	COG0203	ribosomal protein L17
ALFP_RS17960	COG0202	RNA polymerase activity
ALFP_RS17965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALFP_RS17970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALFP_RS17975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALFP_RS17980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ALFP_RS17990	COG0201	protein transport
ALFP_RS17995	COG0200	Binds to the 23S rRNA
ALFP_RS18000	COG1841	ribosomal large subunit assembly
ALFP_RS18005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALFP_RS18010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALFP_RS18015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALFP_RS18020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALFP_RS18025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALFP_RS18030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALFP_RS18035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALFP_RS18040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALFP_RS18185	COG1538	Outer membrane efflux protein
ALFP_RS18205	COG0183	Belongs to the thiolase family
ALFP_RS18215	COG2067	long-chain fatty acid transport protein
ALFP_RS18230	COG0318	PFAM AMP-dependent synthetase and ligase
ALFP_RS18235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ALFP_RS18240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALFP_RS18245	COG1648	precorrin-2 dehydrogenase activity
ALFP_RS18245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALFP_RS18260	COG1116	anion transmembrane transporter activity
ALFP_RS18280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALFP_RS18285	COG0255	Belongs to the universal ribosomal protein uL29 family
ALFP_RS18290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALFP_RS18295	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALFP_RS18300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALFP_RS18305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALFP_RS18310	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALFP_RS18315	COG0089	rRNA binding
ALFP_RS18320	COG0088	Forms part of the polypeptide exit tunnel
ALFP_RS18325	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALFP_RS18330	COG4175	Glycine betaine
ALFP_RS18335	COG4176	ABC-type proline glycine betaine transport system permease component
ALFP_RS18345	COG0051	transcription antitermination factor activity, RNA binding
ALFP_RS18350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALFP_RS18355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALFP_RS18360	COG0049	tRNA binding
ALFP_RS18365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALFP_RS18395	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ALFP_RS18400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALFP_RS18405	COG0085	RNA polymerase activity
ALFP_RS18410	COG0222	ribosome binding
ALFP_RS18415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALFP_RS18425	COG0081	regulation of translation
ALFP_RS18450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALFP_RS18475	COG1475	DNA binding
ALFP_RS18480	COG1192	Involved in chromosome partitioning
ALFP_RS18485	COG0357	Ribosomal RNA small subunit methyltransferase G
ALFP_RS18490	COG0445	tRNA wobble uridine modification
ALFP_RS18495	COG0436	Aminotransferase
ALFP_RS18500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALFP_RS18510	COG3706	GGDEF domain
ALFP_RS18515	COG0688	phosphatidylethanolamine metabolic process
ALFP_RS18525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALFP_RS18565	COG3645	SOS response
ALFP_RS18570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALFP_RS18605	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALFP_RS18625	COG0596	Alpha beta hydrolase
ALFP_RS18630	COG2309	aminopeptidase activity
ALFP_RS18635	COG1335	isochorismatase
ALFP_RS18660	COG0753	catalase activity
ALFP_RS18665	COG0706	membrane insertase activity
ALFP_RS18670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALFP_RS18675	COG0594	ribonuclease P activity
ALFP_RS18680	COG0230	Belongs to the bacterial ribosomal protein bL34 family