locus-tag	class	description
GTU60_RS00025	COG1538	Outer membrane efflux protein
GTU60_RS00040	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS00045	COG0183	Belongs to the thiolase family
GTU60_RS00055	COG2067	long-chain fatty acid transport protein
GTU60_RS00070	COG0318	PFAM AMP-dependent synthetase and ligase
GTU60_RS00075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTU60_RS00080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GTU60_RS00085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTU60_RS00085	COG1648	precorrin-2 dehydrogenase activity
GTU60_RS00100	COG1116	anion transmembrane transporter activity
GTU60_RS00120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GTU60_RS00125	COG0255	Belongs to the universal ribosomal protein uL29 family
GTU60_RS00130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GTU60_RS00135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GTU60_RS00140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GTU60_RS00145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GTU60_RS00150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTU60_RS00155	COG0089	rRNA binding
GTU60_RS00160	COG0088	Forms part of the polypeptide exit tunnel
GTU60_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GTU60_RS00170	COG4175	Glycine betaine
GTU60_RS00175	COG4176	ABC-type proline glycine betaine transport system permease component
GTU60_RS00180	COG0051	transcription antitermination factor activity, RNA binding
GTU60_RS00185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTU60_RS00190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTU60_RS00195	COG0049	tRNA binding
GTU60_RS00200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GTU60_RS00230	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GTU60_RS00235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GTU60_RS00240	COG0085	RNA polymerase activity
GTU60_RS00245	COG0222	ribosome binding
GTU60_RS00250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GTU60_RS00255	COG0081	regulation of translation
GTU60_RS00280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTU60_RS00300	COG1475	DNA binding
GTU60_RS00305	COG1192	Involved in chromosome partitioning
GTU60_RS00310	COG0357	Ribosomal RNA small subunit methyltransferase G
GTU60_RS00315	COG0445	tRNA wobble uridine modification
GTU60_RS00320	COG0436	Aminotransferase
GTU60_RS00330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GTU60_RS00335	COG3706	GGDEF domain
GTU60_RS00340	COG0688	phosphatidylethanolamine metabolic process
GTU60_RS00350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTU60_RS00440	COG0582	viral genome integration into host DNA
GTU60_RS00445	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GTU60_RS00480	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS00500	COG0596	Alpha beta hydrolase
GTU60_RS00505	COG2309	aminopeptidase activity
GTU60_RS00510	COG1335	isochorismatase
GTU60_RS00535	COG0753	catalase activity
GTU60_RS00540	COG0706	membrane insertase activity
GTU60_RS00545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GTU60_RS00550	COG0594	ribonuclease P activity
GTU60_RS00555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GTU60_RS00560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTU60_RS00565	COG0592	DNA-directed DNA polymerase activity
GTU60_RS00575	COG1187	pseudouridine synthase activity
GTU60_RS00590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS00615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS00620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU60_RS00640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS00660	COG2070	2-Nitropropane dioxygenase
GTU60_RS00670	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS00680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS00690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS00700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS00720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GTU60_RS00725	COG0583	DNA-binding transcription factor activity
GTU60_RS00735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS00745	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS00760	COG0318	PFAM AMP-dependent synthetase and ligase
GTU60_RS00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU60_RS00770	COG0596	Alpha beta hydrolase
GTU60_RS00775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS00790	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS00800	COG0697	spore germination
GTU60_RS00805	COG0583	DNA-binding transcription factor activity
GTU60_RS00815	COG3842	ATPase activity
GTU60_RS00825	COG0436	Aminotransferase
GTU60_RS00835	COG0523	cobalamin synthesis protein
GTU60_RS00890	COG1846	Transcriptional regulator
GTU60_RS00910	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTU60_RS00915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU60_RS00920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GTU60_RS00930	COG4638	Rieske (2fe-2S)
GTU60_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS01005	COG2207	Transcriptional regulator
GTU60_RS01035	COG1595	DNA-templated transcription, initiation
GTU60_RS01040	COG4608	Belongs to the ABC transporter superfamily
GTU60_RS01045	COG0444	Belongs to the ABC transporter superfamily
GTU60_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU60_RS01055	COG0601	transmembrane transport
GTU60_RS01065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GTU60_RS01070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTU60_RS01075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTU60_RS01080	COG0431	NADPH-dependent FMN reductase
GTU60_RS01100	COG0583	DNA-binding transcription factor activity
GTU60_RS01110	COG4149	molybdate abc transporter
GTU60_RS01120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GTU60_RS01125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTU60_RS01135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS01155	COG0028	Belongs to the TPP enzyme family
GTU60_RS01160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS01190	COG2922	Belongs to the Smg family
GTU60_RS01210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GTU60_RS01215	COG0183	Belongs to the thiolase family
GTU60_RS01220	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GTU60_RS01225	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS01245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTU60_RS01255	COG0018	arginyl-trna synthetase
GTU60_RS01275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTU60_RS01290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GTU60_RS01295	COG4774	siderophore transport
GTU60_RS01300	COG0066	3-isopropylmalate dehydratase activity
GTU60_RS01305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GTU60_RS01310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTU60_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS01320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS01320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTU60_RS01330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS01335	COG1335	isochorismatase
GTU60_RS01340	COG0583	DNA-binding transcription factor activity
GTU60_RS01360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GTU60_RS01365	COG1280	lysine exporter protein (LysE YggA)
GTU60_RS01370	COG0513	Belongs to the DEAD box helicase family
GTU60_RS01380	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GTU60_RS01395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GTU60_RS01410	COG0154	amidase activity
GTU60_RS01425	COG0583	DNA-binding transcription factor activity
GTU60_RS01455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTU60_RS01460	COG1127	ABC transporter
GTU60_RS01465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTU60_RS01465	COG3218	ABC-type transport auxiliary lipoprotein component
GTU60_RS01480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU60_RS01485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS01495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS01525	COG0583	DNA-binding transcription factor activity
GTU60_RS01550	COG4680	protein conserved in bacteria
GTU60_RS01570	COG2358	TRAP transporter, solute receptor (TAXI family
GTU60_RS01580	COG0564	pseudouridine synthase activity
GTU60_RS01585	COG0252	asparaginase activity
GTU60_RS01610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GTU60_RS01615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTU60_RS01620	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS01640	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS01680	COG0758	DNA mediated transformation
GTU60_RS01685	COG0242	peptide deformylase activity
GTU60_RS01690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GTU60_RS01695	COG0697	spore germination
GTU60_RS01710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS01725	COG4336	lyase activity
GTU60_RS01730	COG0583	DNA-binding transcription factor activity
GTU60_RS01735	COG0859	PFAM glycosyl transferase family 9
GTU60_RS01745	COG1278	Cold shock
GTU60_RS01750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GTU60_RS01755	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GTU60_RS01760	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GTU60_RS01760	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GTU60_RS01770	COG1686	Belongs to the peptidase S11 family
GTU60_RS01780	COG2921	Belongs to the UPF0250 family
GTU60_RS01785	COG0321	lipoyl(octanoyl) transferase activity
GTU60_RS01790	COG1024	Enoyl-CoA hydratase
GTU60_RS01795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GTU60_RS01805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GTU60_RS01850	COG0826	peptidase U32
GTU60_RS01860	COG3154	lipid carrier protein
GTU60_RS01885	COG0134	indole-3-glycerol-phosphate synthase activity
GTU60_RS01890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTU60_RS01895	COG0512	Glutamine amidotransferase of anthranilate synthase
GTU60_RS01905	COG0546	phosphoglycolate phosphatase activity
GTU60_RS01915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTU60_RS01920	COG2967	ApaG domain
GTU60_RS01925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GTU60_RS01930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS01935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTU60_RS01945	COG0840	transmembrane signaling receptor activity
GTU60_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS01960	COG1535	isochorismatase
GTU60_RS01960	COG3433	isochorismatase activity
GTU60_RS01965	COG1169	isochorismate synthase
GTU60_RS01980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GTU60_RS01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTU60_RS01985	COG1535	isochorismatase
GTU60_RS01985	COG3433	isochorismatase activity
GTU60_RS01990	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTU60_RS02020	COG0683	leucine binding
GTU60_RS02035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS02070	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GTU60_RS02075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTU60_RS02080	COG2819	hydrolase of the alpha beta superfamily
GTU60_RS02085	COG0513	Belongs to the DEAD box helicase family
GTU60_RS02090	COG2814	Major facilitator Superfamily
GTU60_RS02100	COG0583	DNA-binding transcription factor activity
GTU60_RS02110	COG1253	flavin adenine dinucleotide binding
GTU60_RS02145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTU60_RS02155	COG2311	Membrane
GTU60_RS02195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTU60_RS02215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS02220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GTU60_RS02230	COG0583	DNA-binding transcription factor activity
GTU60_RS02235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS02245	COG0765	amino acid transport
GTU60_RS02250	COG0765	amino acid transport
GTU60_RS02255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU60_RS02260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTU60_RS02275	COG3391	amine dehydrogenase activity
GTU60_RS02285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTU60_RS02310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GTU60_RS02315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GTU60_RS02320	COG0210	DNA helicase
GTU60_RS02335	COG0067	glutamate synthase
GTU60_RS02335	COG0069	glutamate synthase activity
GTU60_RS02335	COG0070	glutamate synthase
GTU60_RS02340	COG1024	Enoyl-CoA hydratase
GTU60_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS02355	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTU60_RS02385	COG2918	glutathione biosynthetic process
GTU60_RS02395	COG2197	response regulator
GTU60_RS02400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GTU60_RS02410	COG2223	nitrite transmembrane transporter activity
GTU60_RS02415	COG2860	membrane
GTU60_RS02420	COG1346	cytolysis
GTU60_RS02435	COG0251	oxidation-reduction process
GTU60_RS02450	COG5295	Hep Hag repeat protein
GTU60_RS02465	COG1280	lysine exporter protein (LysE YggA)
GTU60_RS02475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GTU60_RS02490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GTU60_RS02505	COG2096	Adenosyltransferase
GTU60_RS02520	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GTU60_RS02525	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GTU60_RS02535	COG0523	cobalamin synthesis protein
GTU60_RS02540	COG0735	belongs to the Fur family
GTU60_RS02555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTU60_RS02560	COG0803	Belongs to the bacterial solute-binding protein 9 family
GTU60_RS02565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GTU60_RS02575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GTU60_RS02580	COG1560	Kdo2-lipid A biosynthetic process
GTU60_RS02590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GTU60_RS02595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GTU60_RS02600	COG1950	PFAM Membrane protein of
GTU60_RS02635	COG0275	rRNA processing
GTU60_RS02640	COG0730	response to heat
GTU60_RS02645	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GTU60_RS02650	COG0129	dihydroxy-acid dehydratase activity
GTU60_RS02655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GTU60_RS02675	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS02685	COG0628	permease
GTU60_RS02690	COG0582	viral genome integration into host DNA
GTU60_RS02755	COG5377	YqaJ viral recombinase family
GTU60_RS02760	COG2003	Belongs to the UPF0758 family
GTU60_RS02775	COG3620	sequence-specific DNA binding
GTU60_RS02805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS02845	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTU60_RS02860	COG2814	Major facilitator Superfamily
GTU60_RS02880	COG1846	Transcriptional regulator
GTU60_RS02895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU60_RS02905	COG0789	Transcriptional regulator
GTU60_RS02915	COG4774	siderophore transport
GTU60_RS02920	COG4607	ABC-type enterochelin transport system periplasmic component
GTU60_RS02925	COG4604	ABC transporter, ATP-binding protein
GTU60_RS02930	COG4605	iron ion homeostasis
GTU60_RS02935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTU60_RS02940	COG1132	(ABC) transporter
GTU60_RS02945	COG2375	cellular response to nickel ion
GTU60_RS02945	COG1132	(ABC) transporter
GTU60_RS02950	COG0277	FAD linked oxidase domain protein
GTU60_RS02955	COG1304	FMN binding
GTU60_RS02960	COG2186	Transcriptional regulator
GTU60_RS02980	COG2188	Transcriptional regulator
GTU60_RS02985	COG1522	sequence-specific DNA binding
GTU60_RS02990	COG3844	kynureninase activity
GTU60_RS02995	COG1113	amino acid transport
GTU60_RS03025	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS03030	COG1349	DNA-binding transcription factor activity
GTU60_RS03035	COG3842	ATPase activity
GTU60_RS03050	COG0395	ABC-type sugar transport system, permease component
GTU60_RS03075	COG0861	Integral membrane protein TerC family
GTU60_RS03080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU60_RS03090	COG1671	Belongs to the UPF0178 family
GTU60_RS03100	COG1418	mRNA catabolic process
GTU60_RS03110	COG4948	Mandelate Racemase Muconate Lactonizing
GTU60_RS03120	COG0477	Major facilitator Superfamily
GTU60_RS03135	COG0154	amidase activity
GTU60_RS03145	COG0583	DNA-binding transcription factor activity
GTU60_RS03170	COG0326	Molecular chaperone. Has ATPase activity
GTU60_RS03175	COG4774	siderophore transport
GTU60_RS03180	COG3128	pkhd-type hydroxylase
GTU60_RS03190	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTU60_RS03205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTU60_RS03210	COG1652	LysM domain
GTU60_RS03225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GTU60_RS03245	COG3433	isochorismatase activity
GTU60_RS03245	COG1535	isochorismatase
GTU60_RS03270	COG0583	DNA-binding transcription factor activity
GTU60_RS03275	COG0387	Pfam Sodium calcium exchanger
GTU60_RS03290	COG0477	Major facilitator Superfamily
GTU60_RS03295	COG0235	Class ii aldolase
GTU60_RS03310	COG3391	amine dehydrogenase activity
GTU60_RS03315	COG0590	tRNA wobble adenosine to inosine editing
GTU60_RS03320	COG3257	ureidoglycine aminohydrolase activity
GTU60_RS03325	COG0583	DNA-binding transcription factor activity
GTU60_RS03330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GTU60_RS03335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTU60_RS03335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTU60_RS03345	COG0489	protein tyrosine kinase activity
GTU60_RS03370	COG2081	HI0933 family
GTU60_RS03375	COG0509	glycine decarboxylation via glycine cleavage system
GTU60_RS03385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GTU60_RS03390	COG1765	OsmC-like protein
GTU60_RS03395	COG3278	Belongs to the heme-copper respiratory oxidase family
GTU60_RS03420	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GTU60_RS03425	COG0469	pyruvate kinase activity
GTU60_RS03430	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GTU60_RS03440	COG2084	Dehydrogenase
GTU60_RS03445	COG3622	Belongs to the hyi family
GTU60_RS03450	COG3960	tartronate-semialdehyde synthase activity
GTU60_RS03455	COG0583	DNA-binding transcription factor activity
GTU60_RS03465	COG2233	PERMEase
GTU60_RS03470	COG1942	4-Oxalocrotonate Tautomerase
GTU60_RS03475	COG0235	Class ii aldolase
GTU60_RS03485	COG3648	Uricase
GTU60_RS03485	COG3195	allantoin biosynthetic process
GTU60_RS03495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GTU60_RS03500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTU60_RS03515	COG0438	transferase activity, transferring glycosyl groups
GTU60_RS03525	COG0438	transferase activity, transferring glycosyl groups
GTU60_RS03535	COG0277	FAD linked oxidase domain protein
GTU60_RS03545	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTU60_RS03550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GTU60_RS03560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS03570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GTU60_RS03580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GTU60_RS03595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GTU60_RS03600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GTU60_RS03605	COG0193	aminoacyl-tRNA hydrolase activity
GTU60_RS03615	COG0012	GTP binding
GTU60_RS03630	COG0488	(ABC) transporter
GTU60_RS03645	COG0288	reversible hydration of carbon dioxide
GTU60_RS03650	COG0583	DNA-binding transcription factor activity
GTU60_RS03680	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GTU60_RS03690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTU60_RS03695	COG3088	subunit of a heme lyase
GTU60_RS03700	COG4235	cytochrome complex assembly
GTU60_RS03705	COG0785	Cytochrome C biogenesis protein
GTU60_RS03715	COG2169	Transcriptional regulator
GTU60_RS03715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTU60_RS03735	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS03745	COG0411	ABC transporter
GTU60_RS03755	COG1858	cytochrome C peroxidase
GTU60_RS03760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTU60_RS03765	COG1959	2 iron, 2 sulfur cluster binding
GTU60_RS03770	COG2346	COG2346, Truncated hemoglobins
GTU60_RS03775	COG0463	Glycosyl transferase, family 2
GTU60_RS03815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GTU60_RS03820	COG3383	formate dehydrogenase (NAD+) activity
GTU60_RS03835	COG1910	domain protein
GTU60_RS03840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GTU60_RS03850	COG0303	'Molybdopterin
GTU60_RS03855	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTU60_RS03860	COG0314	molybdopterin synthase activity
GTU60_RS03870	COG0315	cyclic pyranopterin monophosphate synthase activity
GTU60_RS03900	COG0678	peroxiredoxin activity
GTU60_RS03915	COG0697	spore germination
GTU60_RS03920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTU60_RS03955	COG2814	Major facilitator Superfamily
GTU60_RS03995	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GTU60_RS04000	COG4535	Mg2 and Co2 transporter CorC
GTU60_RS04005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GTU60_RS04010	COG1702	phosphate starvation-inducible protein PhoH
GTU60_RS04015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTU60_RS04030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTU60_RS04035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTU60_RS04040	COG1862	Preprotein translocase
GTU60_RS04045	COG0343	queuine tRNA-ribosyltransferase activity
GTU60_RS04050	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GTU60_RS04055	COG2027	D-alanyl-D-alanine carboxypeptidase
GTU60_RS04060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GTU60_RS04070	COG4575	ribosome binding
GTU60_RS04085	COG0583	DNA-binding transcription factor activity
GTU60_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU60_RS04115	COG0154	amidase activity
GTU60_RS04125	COG0477	Major facilitator Superfamily
GTU60_RS04140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTU60_RS04150	COG0436	Aminotransferase
GTU60_RS04160	COG0280	phosphate acetyltransferase
GTU60_RS04160	COG0281	malic enzyme
GTU60_RS04170	COG2732	(Barnase) inhibitor
GTU60_RS04175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GTU60_RS04180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTU60_RS04185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTU60_RS04190	COG0126	phosphoglycerate kinase activity
GTU60_RS04210	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTU60_RS04220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GTU60_RS04225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GTU60_RS04230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GTU60_RS04235	COG0009	L-threonylcarbamoyladenylate synthase
GTU60_RS04240	COG0596	Alpha beta hydrolase
GTU60_RS04245	COG2030	dehydratase
GTU60_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS04250	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS04260	COG0405	Gamma-glutamyltransferase
GTU60_RS04270	COG0579	oxidoreductase
GTU60_RS04275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTU60_RS04280	COG0259	pyridoxamine-phosphate oxidase activity
GTU60_RS04290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GTU60_RS04305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GTU60_RS04310	COG1215	transferase activity, transferring glycosyl groups
GTU60_RS04320	COG0488	(ABC) transporter
GTU60_RS04340	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GTU60_RS04345	COG2894	cell division
GTU60_RS04355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTU60_RS04360	COG1271	oxidase subunit
GTU60_RS04365	COG1294	oxidase, subunit
GTU60_RS04370	COG0038	chloride channel
GTU60_RS04380	COG0514	ATP-dependent DNA helicase (RecQ)
GTU60_RS04385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTU60_RS04390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTU60_RS04395	COG0633	Ferredoxin
GTU60_RS04400	COG0488	(ABC) transporter
GTU60_RS04410	COG2001	Belongs to the MraZ family
GTU60_RS04415	COG0275	rRNA processing
GTU60_RS04420	COG3116	cell division
GTU60_RS04430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GTU60_RS04435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GTU60_RS04440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GTU60_RS04450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GTU60_RS04455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTU60_RS04460	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTU60_RS04465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GTU60_RS04480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GTU60_RS04490	COG0739	heme binding
GTU60_RS04490	COG1196	nuclear chromosome segregation
GTU60_RS04490	COG0741	lytic transglycosylase activity
GTU60_RS04495	COG0653	protein targeting
GTU60_RS04505	COG2239	Acts as a magnesium transporter
GTU60_RS04515	COG1473	amidohydrolase
GTU60_RS04520	COG0318	PFAM AMP-dependent synthetase and ligase
GTU60_RS04530	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GTU60_RS04530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS04545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTU60_RS04550	COG2011	ABC-type metal ion transport system permease component
GTU60_RS04560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS04565	COG0765	amino acid transport
GTU60_RS04570	COG1126	abc transporter atp-binding protein
GTU60_RS04590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GTU60_RS04595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU60_RS04600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GTU60_RS04605	COG0700	Nucleoside recognition
GTU60_RS04620	COG0204	Acyl-transferase
GTU60_RS04625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTU60_RS04630	COG0751	glycine-tRNA ligase activity
GTU60_RS04635	COG0752	glycyl-tRNA synthetase alpha subunit
GTU60_RS04645	COG1024	Enoyl-CoA hydratase
GTU60_RS04655	COG1309	transcriptional regulator
GTU60_RS04665	COG2814	Major facilitator Superfamily
GTU60_RS04680	COG1573	uracil-dna glycosylase
GTU60_RS04685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTU60_RS04690	COG0617	tRNA 3'-terminal CCA addition
GTU60_RS04700	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTU60_RS04705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GTU60_RS04710	COG1953	Uracil, thiamine, allantoin
GTU60_RS04715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GTU60_RS04720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GTU60_RS04725	COG0586	Pfam SNARE associated Golgi protein
GTU60_RS04730	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTU60_RS04735	COG0802	atpase or kinase
GTU60_RS04745	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS04750	COG0281	malic enzyme
GTU60_RS04750	COG0280	phosphate acetyltransferase
GTU60_RS04755	COG0583	DNA-binding transcription factor activity
GTU60_RS04760	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS04765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU60_RS04785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS04810	COG1733	regulation of RNA biosynthetic process
GTU60_RS04815	COG2910	NAD(P)H-binding
GTU60_RS04825	COG2223	nitrite transmembrane transporter activity
GTU60_RS04830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTU60_RS04835	COG4974	Belongs to the 'phage' integrase family
GTU60_RS04840	COG0725	ABC transporter, periplasmic molybdate-binding protein
GTU60_RS04845	COG4149	molybdate abc transporter
GTU60_RS04850	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTU60_RS04865	COG1074	ATP-dependent DNA helicase activity
GTU60_RS04900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS04920	COG3391	amine dehydrogenase activity
GTU60_RS04925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GTU60_RS04930	COG0505	Belongs to the CarA family
GTU60_RS04935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GTU60_RS04955	COG2233	PERMEase
GTU60_RS04960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTU60_RS04965	COG1534	Rna-binding protein
GTU60_RS04970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GTU60_RS04975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GTU60_RS04985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTU60_RS04995	COG0248	Ppx GppA phosphatase
GTU60_RS05000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GTU60_RS05020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTU60_RS05025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTU60_RS05075	COG1231	oxidoreductase activity
GTU60_RS05080	COG2010	Cytochrome c
GTU60_RS05085	COG2323	membrane
GTU60_RS05100	COG1368	sulfuric ester hydrolase activity
GTU60_RS05130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTU60_RS05135	COG3327	negative regulation of DNA-templated transcription, initiation
GTU60_RS05140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTU60_RS05155	COG0009	L-threonylcarbamoyladenylate synthase
GTU60_RS05160	COG1994	Peptidase M50
GTU60_RS05165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTU60_RS05170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GTU60_RS05185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GTU60_RS05195	COG0156	8-amino-7-oxononanoate synthase activity
GTU60_RS05200	COG2124	cytochrome p450
GTU60_RS05205	COG3135	benzoate transporter
GTU60_RS05215	COG2850	peptidyl-arginine hydroxylation
GTU60_RS05220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GTU60_RS05225	COG3391	amine dehydrogenase activity
GTU60_RS05235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU60_RS05240	COG0577	efflux transmembrane transporter activity
GTU60_RS05240	COG1136	(ABC) transporter
GTU60_RS05245	COG1538	Outer membrane efflux protein
GTU60_RS05250	COG0363	glucosamine-6-phosphate deaminase activity
GTU60_RS05255	COG1132	(ABC) transporter
GTU60_RS05265	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS05275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTU60_RS05285	COG0668	transmembrane transport
GTU60_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS05295	COG3321	synthase
GTU60_RS05295	COG0604	alcohol dehydrogenase
GTU60_RS05330	COG0154	amidase activity
GTU60_RS05345	COG0483	inositol monophosphate 1-phosphatase activity
GTU60_RS05350	COG1253	flavin adenine dinucleotide binding
GTU60_RS05355	COG1968	undecaprenyl-diphosphatase activity
GTU60_RS05375	COG0215	cysteine-tRNA ligase activity
GTU60_RS05385	COG0825	malonyl-CoA metabolic process
GTU60_RS05390	COG0037	tRNA processing
GTU60_RS05415	COG0330	HflC and HflK could
GTU60_RS05430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU60_RS05450	COG4208	sulfate ABC transporter
GTU60_RS05455	COG3842	ATPase activity
GTU60_RS05465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GTU60_RS05500	COG1304	FMN binding
GTU60_RS05505	COG0435	Glutathione S-transferase
GTU60_RS05510	COG0655	NAD(P)H dehydrogenase (quinone) activity
GTU60_RS05530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GTU60_RS05535	COG2363	Small membrane protein
GTU60_RS05540	COG0598	Magnesium transport protein CorA
GTU60_RS05545	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS05555	COG0747	negative chemotaxis
GTU60_RS05565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU60_RS05570	COG4172	Belongs to the ABC transporter superfamily
GTU60_RS05580	COG3284	Transcriptional regulator
GTU60_RS05585	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS05590	COG1454	alcohol dehydrogenase
GTU60_RS05595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTU60_RS05620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS05650	COG3829	transcription factor binding
GTU60_RS05655	COG0477	Major facilitator Superfamily
GTU60_RS05665	COG0039	L-malate dehydrogenase activity
GTU60_RS05670	COG2188	Transcriptional regulator
GTU60_RS05675	COG2009	succinate dehydrogenase
GTU60_RS05685	COG1053	succinate dehydrogenase
GTU60_RS05690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTU60_RS05695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GTU60_RS05700	COG0372	Belongs to the citrate synthase family
GTU60_RS05705	COG2186	Transcriptional regulator
GTU60_RS05710	COG1620	l-lactate permease
GTU60_RS05715	COG0280	phosphate acetyltransferase
GTU60_RS05715	COG0281	malic enzyme
GTU60_RS05720	COG0567	Dehydrogenase, E1 component
GTU60_RS05725	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU60_RS05730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTU60_RS05735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTU60_RS05755	COG2183	response to ionizing radiation
GTU60_RS05760	COG1199	ATP-dependent helicase activity
GTU60_RS05770	COG1733	regulation of RNA biosynthetic process
GTU60_RS05785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS05785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GTU60_RS05790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS05800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS05800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTU60_RS05815	COG0564	pseudouridine synthase activity
GTU60_RS05825	COG3243	poly(R)-hydroxyalkanoic acid synthase
GTU60_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS05835	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GTU60_RS05860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GTU60_RS05865	COG1187	pseudouridine synthase activity
GTU60_RS05870	COG0779	Required for maturation of 30S ribosomal subunits
GTU60_RS05875	COG0195	Participates in both transcription termination and antitermination
GTU60_RS05875	COG2251	uridine kinase activity
GTU60_RS05880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GTU60_RS05885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GTU60_RS05890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GTU60_RS05895	COG1217	gtp-binding protein TYPA
GTU60_RS05900	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTU60_RS05910	COG4160	amino acid transport
GTU60_RS05915	COG4215	(ABC) transporter
GTU60_RS05935	COG1283	sodium-dependent phosphate transmembrane transporter activity
GTU60_RS05945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTU60_RS05960	COG0501	Belongs to the peptidase M48B family
GTU60_RS05975	COG1722	exodeoxyribonuclease VII activity
GTU60_RS05980	COG0142	geranyltranstransferase activity
GTU60_RS05990	COG1469	GTP cyclohydrolase I activity
GTU60_RS05995	COG0360	Binds together with S18 to 16S ribosomal RNA
GTU60_RS06000	COG2965	DNA replication, synthesis of RNA primer
GTU60_RS06005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GTU60_RS06015	COG0305	Participates in initiation and elongation during chromosome replication
GTU60_RS06025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTU60_RS06030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GTU60_RS06035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTU60_RS06045	COG0436	Aminotransferase
GTU60_RS06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTU60_RS06065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GTU60_RS06070	COG1562	ergosterol biosynthetic process
GTU60_RS06075	COG1562	ergosterol biosynthetic process
GTU60_RS06080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTU60_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS06110	COG3842	ATPase activity
GTU60_RS06115	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTU60_RS06120	COG1177	transmembrane transport
GTU60_RS06125	COG1393	Belongs to the ArsC family
GTU60_RS06130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GTU60_RS06135	COG0704	Plays a role in the regulation of phosphate uptake
GTU60_RS06140	COG2203	Gaf domain
GTU60_RS06140	COG3706	GGDEF domain
GTU60_RS06140	COG4251	negative regulation of phosphorylation
GTU60_RS06140	COG5001	Diguanylate cyclase
GTU60_RS06145	COG0659	secondary active sulfate transmembrane transporter activity
GTU60_RS06150	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GTU60_RS06155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTU60_RS06155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GTU60_RS06160	COG1643	Atp-dependent helicase
GTU60_RS06170	COG0438	transferase activity, transferring glycosyl groups
GTU60_RS06175	COG0726	polysaccharide deacetylase
GTU60_RS06190	COG0438	transferase activity, transferring glycosyl groups
GTU60_RS06215	COG1132	(ABC) transporter
GTU60_RS06230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GTU60_RS06270	COG2186	Transcriptional regulator
GTU60_RS06275	COG0277	FAD linked oxidase domain protein
GTU60_RS06280	COG0277	FAD linked oxidase domain protein
GTU60_RS06285	COG0247	lactate metabolic process
GTU60_RS06310	COG0628	permease
GTU60_RS06315	COG1283	sodium-dependent phosphate transmembrane transporter activity
GTU60_RS06330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS06340	COG0697	spore germination
GTU60_RS06355	COG2855	membrane
GTU60_RS06360	COG3094	Invasion gene expression up-regulator, SirB
GTU60_RS06370	COG0640	Transcriptional regulator
GTU60_RS06395	COG0659	secondary active sulfate transmembrane transporter activity
GTU60_RS06400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GTU60_RS06410	COG2314	TM2 domain
GTU60_RS06415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GTU60_RS06420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTU60_RS06425	COG0791	NLP P60 protein
GTU60_RS06445	COG1360	Flagellar Motor Protein
GTU60_RS06455	COG0835	chemotaxis
GTU60_RS06460	COG0840	transmembrane signaling receptor activity
GTU60_RS06465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTU60_RS06475	COG0745	RESPONSE REGULATOR receiver
GTU60_RS06480	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GTU60_RS06490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GTU60_RS06515	COG1815	bacterial-type flagellum-dependent cell motility
GTU60_RS06520	COG1558	bacterial-type flagellum-dependent cell motility
GTU60_RS06525	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GTU60_RS06565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTU60_RS06590	COG2176	DNA-directed DNA polymerase activity
GTU60_RS06600	COG1987	bacterial-type flagellum assembly
GTU60_RS06615	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTU60_RS06640	COG1157	protein secretion by the type III secretion system
GTU60_RS06655	COG1766	The M ring may be actively involved in energy transduction
GTU60_RS06660	COG1677	Flagellar hook-basal body complex protein FliE
GTU60_RS06665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GTU60_RS06690	COG1334	flagellar protein FlaG
GTU60_RS06695	COG1191	sigma factor activity
GTU60_RS06740	COG1136	(ABC) transporter
GTU60_RS06750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GTU60_RS06770	COG2733	membrane
GTU60_RS06775	COG0840	transmembrane signaling receptor activity
GTU60_RS06780	COG0840	transmembrane signaling receptor activity
GTU60_RS06805	COG2610	gluconate transmembrane transporter activity
GTU60_RS06815	COG0582	viral genome integration into host DNA
GTU60_RS06820	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS06835	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GTU60_RS06840	COG3657	addiction module killer protein
GTU60_RS06845	COG4521	taurine ABC transporter
GTU60_RS06850	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GTU60_RS06855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS06865	COG0583	DNA-binding transcription factor activity
GTU60_RS06895	COG2824	Alkylphosphonate utilization operon protein PhnA
GTU60_RS06910	COG4771	TonB-dependent receptor
GTU60_RS06915	COG1858	cytochrome C peroxidase
GTU60_RS06935	COG1113	amino acid transport
GTU60_RS06955	COG0583	DNA-binding transcription factor activity
GTU60_RS06960	COG3755	Protein conserved in bacteria
GTU60_RS06965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GTU60_RS07000	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTU60_RS07025	COG1278	Cold shock
GTU60_RS07030	COG0642	Histidine kinase
GTU60_RS07040	COG3278	Belongs to the heme-copper respiratory oxidase family
GTU60_RS07050	COG2863	cytochrome
GTU60_RS07055	COG3258	Cytochrome c
GTU60_RS07085	COG0025	NhaP-type Na H and K H
GTU60_RS07100	COG1289	transmembrane transporter activity
GTU60_RS07105	COG2252	PERMEase
GTU60_RS07125	COG1999	signal sequence binding
GTU60_RS07140	COG0069	glutamate synthase activity
GTU60_RS07150	COG1846	Transcriptional regulator
GTU60_RS07160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GTU60_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS07210	COG3264	Mechanosensitive ion channel
GTU60_RS07210	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GTU60_RS07215	COG3264	Mechanosensitive ion channel
GTU60_RS07215	COG1511	domain protein
GTU60_RS07220	COG0477	Major facilitator Superfamily
GTU60_RS07235	COG1396	sequence-specific DNA binding
GTU60_RS07240	COG3437	response regulator, receiver
GTU60_RS07245	COG2205	protein histidine kinase activity
GTU60_RS07245	COG0784	Response regulator, receiver
GTU60_RS07245	COG2198	Histidine kinase
GTU60_RS07250	COG2239	Acts as a magnesium transporter
GTU60_RS07260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTU60_RS07265	COG1490	D-aminoacyl-tRNA deacylase activity
GTU60_RS07280	COG0456	acetyltransferase
GTU60_RS07290	COG0501	Belongs to the peptidase M48B family
GTU60_RS07295	COG2814	Major facilitator Superfamily
GTU60_RS07350	COG2199	diguanylate cyclase activity
GTU60_RS07365	COG1522	sequence-specific DNA binding
GTU60_RS07370	COG0626	cystathionine gamma-synthase activity
GTU60_RS07380	COG0494	nUDIX hydrolase
GTU60_RS07385	COG2832	Protein of unknown function (DUF454)
GTU60_RS07395	COG0137	argininosuccinate synthase activity
GTU60_RS07400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GTU60_RS07405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTU60_RS07425	COG1609	Transcriptional regulator
GTU60_RS07435	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GTU60_RS07445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GTU60_RS07450	COG2205	protein histidine kinase activity
GTU60_RS07455	COG0745	RESPONSE REGULATOR receiver
GTU60_RS07460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GTU60_RS07470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTU60_RS07475	COG0268	Binds directly to 16S ribosomal RNA
GTU60_RS07480	COG0728	peptidoglycan biosynthetic process
GTU60_RS07490	COG0563	adenylate kinase activity
GTU60_RS07495	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GTU60_RS07500	COG2835	tetraacyldisaccharide 4'-kinase activity
GTU60_RS07505	COG1663	tetraacyldisaccharide 4'-kinase activity
GTU60_RS07510	COG0848	biopolymer transport protein
GTU60_RS07515	COG0811	peptide transport
GTU60_RS07520	COG1570	exodeoxyribonuclease VII activity
GTU60_RS07525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GTU60_RS07535	COG0183	Belongs to the thiolase family
GTU60_RS07545	COG1278	Cold shock
GTU60_RS07550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GTU60_RS07555	COG0542	response to heat
GTU60_RS07560	COG2995	paraquat-inducible protein a
GTU60_RS07565	COG3008	intermembrane lipid transfer
GTU60_RS07565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTU60_RS07585	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS07620	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GTU60_RS07625	COG0756	dUTP diphosphatase activity
GTU60_RS07635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GTU60_RS07640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GTU60_RS07645	COG0196	riboflavin kinase activity
GTU60_RS07650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GTU60_RS07655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTU60_RS07655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GTU60_RS07665	COG0210	DNA helicase
GTU60_RS07720	COG0488	(ABC) transporter
GTU60_RS07725	COG2890	protein-(glutamine-N5) methyltransferase activity
GTU60_RS07730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTU60_RS07735	COG2171	N-acyltransferase activity
GTU60_RS07745	COG2207	Transcriptional regulator
GTU60_RS07755	COG0471	metal ion transport
GTU60_RS07755	COG3273	potassium ion transport
GTU60_RS07800	COG0789	Transcriptional regulator
GTU60_RS07815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS07820	COG0544	peptidyl-prolyl cis-trans isomerase activity
GTU60_RS07825	COG0740	serine-type endopeptidase activity
GTU60_RS07835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GTU60_RS07845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTU60_RS07855	COG0556	nucleotide-excision repair
GTU60_RS07860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GTU60_RS07870	COG1104	cysteine desulfurase activity
GTU60_RS07880	COG0316	Belongs to the HesB IscA family
GTU60_RS07895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GTU60_RS07900	COG4221	oxidoreductase activity
GTU60_RS07910	COG0840	transmembrane signaling receptor activity
GTU60_RS07915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GTU60_RS07920	COG0697	spore germination
GTU60_RS07925	COG0385	Bile acid
GTU60_RS07935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GTU60_RS07950	COG1136	(ABC) transporter
GTU60_RS07955	COG0084	hydrolase, TatD family'
GTU60_RS07970	COG0613	PHP domain protein
GTU60_RS07980	COG0047	phosphoribosylformylglycinamidine synthase activity
GTU60_RS07980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GTU60_RS08005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GTU60_RS08005	COG0519	Catalyzes the synthesis of GMP from XMP
GTU60_RS08030	COG4691	Plasmid stability protein
GTU60_RS08060	COG0798	PFAM Bile acid sodium symporter
GTU60_RS08095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTU60_RS08110	COG0583	DNA-binding transcription factor activity
GTU60_RS08125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTU60_RS08135	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS08145	COG2378	regulation of single-species biofilm formation
GTU60_RS08150	COG0523	cobalamin synthesis protein
GTU60_RS08155	COG1469	GTP cyclohydrolase I activity
GTU60_RS08160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GTU60_RS08170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GTU60_RS08175	COG0735	belongs to the Fur family
GTU60_RS08180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GTU60_RS08200	COG0745	RESPONSE REGULATOR receiver
GTU60_RS08215	COG0583	DNA-binding transcription factor activity
GTU60_RS08220	COG1289	transmembrane transporter activity
GTU60_RS08230	COG1566	PFAM secretion protein HlyD family protein
GTU60_RS08240	COG1942	4-Oxalocrotonate Tautomerase
GTU60_RS08255	COG3162	membrane
GTU60_RS08260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTU60_RS08270	COG2070	2-Nitropropane dioxygenase
GTU60_RS08295	COG1309	transcriptional regulator
GTU60_RS08310	COG0625	glutathione transferase activity
GTU60_RS08315	COG0583	DNA-binding transcription factor activity
GTU60_RS08335	COG0625	glutathione transferase activity
GTU60_RS08340	COG0740	serine-type endopeptidase activity
GTU60_RS08390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GTU60_RS08400	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS08425	COG0640	Transcriptional regulator
GTU60_RS08450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTU60_RS08475	COG3485	protocatechuate 3,4-dioxygenase
GTU60_RS08485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GTU60_RS08490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GTU60_RS08500	COG3135	benzoate transporter
GTU60_RS08505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GTU60_RS08510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GTU60_RS08520	COG4555	ABC transporter
GTU60_RS08530	COG2197	response regulator
GTU60_RS08535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GTU60_RS08560	COG1846	Transcriptional regulator
GTU60_RS08565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS08570	COG2271	Major facilitator Superfamily
GTU60_RS08580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTU60_RS08590	COG0697	spore germination
GTU60_RS08610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTU60_RS08615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GTU60_RS08620	COG0667	Aldo Keto reductase
GTU60_RS08635	COG0582	viral genome integration into host DNA
GTU60_RS08740	COG3620	sequence-specific DNA binding
GTU60_RS08800	COG5410	chromosome segregation
GTU60_RS08925	COG3772	lysozyme
GTU60_RS08970	COG1272	protein, Hemolysin III
GTU60_RS08975	COG3422	double-strand break repair
GTU60_RS08995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS09000	COG0765	amino acid transport
GTU60_RS09005	COG0765	amino acid transport
GTU60_RS09010	COG1126	abc transporter atp-binding protein
GTU60_RS09060	COG2871	sodium ion transport
GTU60_RS09090	COG2814	Major facilitator Superfamily
GTU60_RS09095	COG1280	lysine exporter protein (LysE YggA)
GTU60_RS09115	COG0402	S-adenosylhomocysteine deaminase activity
GTU60_RS09140	COG0330	HflC and HflK could
GTU60_RS09145	COG1585	Membrane protein implicated in regulation of membrane protease activity
GTU60_RS09150	COG2226	methyltransferase
GTU60_RS09160	COG3042	response to heat
GTU60_RS09170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU60_RS09190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GTU60_RS09195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GTU60_RS09210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU60_RS09215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GTU60_RS09245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GTU60_RS09250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GTU60_RS09255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GTU60_RS09260	COG0072	phenylalanine-tRNA ligase activity
GTU60_RS09260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTU60_RS09275	COG2833	Protein of unknown function (DUF455)
GTU60_RS09285	COG5265	(ABC) transporter
GTU60_RS09290	COG1959	2 iron, 2 sulfur cluster binding
GTU60_RS09295	COG0719	Fe-S assembly protein
GTU60_RS09300	COG0396	ATPase activity
GTU60_RS09305	COG0719	Fe-S assembly protein
GTU60_RS09315	COG0822	iron-sulfur transferase activity
GTU60_RS09320	COG2151	metal-sulfur cluster biosynthetic enzyme
GTU60_RS09340	COG1538	Outer membrane efflux protein
GTU60_RS09375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTU60_RS09380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTU60_RS09385	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTU60_RS09405	COG0747	negative chemotaxis
GTU60_RS09410	COG0601	transmembrane transport
GTU60_RS09415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU60_RS09420	COG4172	Belongs to the ABC transporter superfamily
GTU60_RS09430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTU60_RS09475	COG3048	D-serine ammonia-lyase activity
GTU60_RS09480	COG3258	Cytochrome c
GTU60_RS09495	COG3949	Membrane
GTU60_RS09505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GTU60_RS09520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTU60_RS09525	COG0569	domain protein
GTU60_RS09530	COG1902	pentaerythritol trinitrate reductase activity
GTU60_RS09540	COG1610	YqeY-like protein
GTU60_RS09545	COG0587	DNA-directed DNA polymerase activity
GTU60_RS09580	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS09585	COG0583	DNA-binding transcription factor activity
GTU60_RS09590	COG1686	Belongs to the peptidase S11 family
GTU60_RS09605	COG1360	Flagellar Motor Protein
GTU60_RS09615	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS09625	COG4221	oxidoreductase activity
GTU60_RS09635	COG0307	riboflavin synthase, alpha
GTU60_RS09680	COG2233	PERMEase
GTU60_RS09685	COG0071	Belongs to the small heat shock protein (HSP20) family
GTU60_RS09700	COG2814	Major facilitator Superfamily
GTU60_RS09730	COG2816	NAD+ diphosphatase activity
GTU60_RS09735	COG1561	YicC-like family, N-terminal region
GTU60_RS09750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GTU60_RS09755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GTU60_RS09760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTU60_RS09765	COG0174	glutamine synthetase
GTU60_RS09770	COG2153	protein acetylation
GTU60_RS09790	COG3842	ATPase activity
GTU60_RS09795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GTU60_RS09800	COG1840	ABC-type Fe3 transport system, periplasmic component
GTU60_RS09815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GTU60_RS09825	COG0783	Belongs to the Dps family
GTU60_RS09835	COG3842	ATPase activity
GTU60_RS09840	COG0395	ABC-type sugar transport system, permease component
GTU60_RS09845	COG1175	transmembrane transport
GTU60_RS09850	COG1653	transport
GTU60_RS09865	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS09885	COG0625	glutathione transferase activity
GTU60_RS09895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTU60_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS09910	COG0114	fumarate hydratase activity
GTU60_RS09915	COG2133	pyrroloquinoline quinone binding
GTU60_RS09920	COG2226	methyltransferase
GTU60_RS09925	COG0589	response to stress
GTU60_RS09935	COG2207	Transcriptional regulator
GTU60_RS09940	COG0235	Class ii aldolase
GTU60_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS09955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS09960	COG2807	transmembrane transport
GTU60_RS09970	COG0583	DNA-binding transcription factor activity
GTU60_RS10000	COG0583	DNA-binding transcription factor activity
GTU60_RS10005	COG4974	Belongs to the 'phage' integrase family
GTU60_RS10020	COG2132	Multicopper oxidase
GTU60_RS10025	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GTU60_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS10065	COG3038	cytochrome b561
GTU60_RS10075	COG2353	YceI-like domain
GTU60_RS10080	COG1393	Belongs to the ArsC family
GTU60_RS10085	COG0625	glutathione transferase activity
GTU60_RS10105	COG0084	hydrolase, TatD family'
GTU60_RS10110	COG0470	DNA polymerase III
GTU60_RS10120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GTU60_RS10140	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS10145	COG2914	Belongs to the UPF0125 (RnfH) family
GTU60_RS10150	COG2867	negative regulation of translational initiation
GTU60_RS10155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GTU60_RS10160	COG1252	NADH dehydrogenase
GTU60_RS10185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU60_RS10190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GTU60_RS10195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTU60_RS10205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTU60_RS10210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTU60_RS10220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU60_RS10230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GTU60_RS10235	COG0575	Belongs to the CDS family
GTU60_RS10240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GTU60_RS10245	COG0233	cytoplasmic translational termination
GTU60_RS10250	COG0528	UMP kinase activity
GTU60_RS10255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GTU60_RS10260	COG0052	Belongs to the universal ribosomal protein uS2 family
GTU60_RS10265	COG0024	Methionine aminopeptidase
GTU60_RS10270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GTU60_RS10295	COG1286	toxin biosynthetic process
GTU60_RS10305	COG0285	dihydrofolate synthase activity
GTU60_RS10310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTU60_RS10315	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTU60_RS10320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTU60_RS10335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GTU60_RS10345	COG1999	signal sequence binding
GTU60_RS10355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTU60_RS10360	COG0640	Transcriptional regulator
GTU60_RS10380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GTU60_RS10390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU60_RS10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU60_RS10400	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GTU60_RS10420	COG0183	Belongs to the thiolase family
GTU60_RS10425	COG0183	Belongs to the thiolase family
GTU60_RS10435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GTU60_RS10470	COG0194	GDP metabolic process
GTU60_RS10475	COG1758	RNA polymerase activity
GTU60_RS10480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTU60_RS10490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GTU60_RS10495	COG0739	heme binding
GTU60_RS10500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU60_RS10505	COG0584	glycerophosphoryl diester phosphodiesterase
GTU60_RS10510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GTU60_RS10515	COG1187	pseudouridine synthase activity
GTU60_RS10520	COG3161	chorismate lyase activity
GTU60_RS10525	COG2814	Major facilitator Superfamily
GTU60_RS10530	COG0656	L-ascorbic acid biosynthetic process
GTU60_RS10540	COG0668	transmembrane transport
GTU60_RS10545	COG0165	Argininosuccinate lyase
GTU60_RS10550	COG1940	carbohydrate kinase activity
GTU60_RS10550	COG1846	Transcriptional regulator
GTU60_RS10560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS10570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTU60_RS10580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GTU60_RS10585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GTU60_RS10590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GTU60_RS10595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GTU60_RS10600	COG2252	PERMEase
GTU60_RS10605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTU60_RS10625	COG0488	(ABC) transporter
GTU60_RS10630	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTU60_RS10640	COG1131	(ABC) transporter
GTU60_RS10645	COG0842	Transport permease protein
GTU60_RS10655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTU60_RS10655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS10660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTU60_RS10665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTU60_RS10670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS10680	COG2022	thiamine diphosphate biosynthetic process
GTU60_RS10700	COG1414	Transcriptional regulator
GTU60_RS10710	COG0730	response to heat
GTU60_RS10720	COG1666	GTP binding
GTU60_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
GTU60_RS10730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GTU60_RS10735	COG0519	Catalyzes the synthesis of GMP from XMP
GTU60_RS10735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GTU60_RS10740	COG2207	Transcriptional regulator
GTU60_RS10750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTU60_RS10755	COG0135	phosphoribosylanthranilate isomerase activity
GTU60_RS10760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS10770	COG0101	tRNA pseudouridine synthase activity
GTU60_RS10780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTU60_RS10805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTU60_RS10815	COG4566	intracellular signal transduction
GTU60_RS10830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GTU60_RS10835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GTU60_RS10845	COG1295	ribonuclease BN
GTU60_RS10855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTU60_RS10885	COG4964	Belongs to the GSP D family
GTU60_RS10920	COG3712	iron ion homeostasis
GTU60_RS10925	COG1595	DNA-templated transcription, initiation
GTU60_RS10945	COG2959	enzyme of heme biosynthesis
GTU60_RS10955	COG0181	hydroxymethylbilane synthase activity
GTU60_RS10960	COG0861	Integral membrane protein TerC family
GTU60_RS10965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GTU60_RS10970	COG0045	succinate-CoA ligase (ADP-forming) activity
GTU60_RS10985	COG0583	DNA-binding transcription factor activity
GTU60_RS10990	COG2137	regulation of response to DNA damage stimulus
GTU60_RS10995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GTU60_RS11010	COG0477	Major facilitator Superfamily
GTU60_RS11025	COG0318	PFAM AMP-dependent synthetase and ligase
GTU60_RS11030	COG1024	Enoyl-CoA hydratase
GTU60_RS11035	COG3162	membrane
GTU60_RS11050	COG0540	Belongs to the ATCase OTCase family
GTU60_RS11065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTU60_RS11080	COG2070	2-Nitropropane dioxygenase
GTU60_RS11090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTU60_RS11090	COG2111	Na H antiporter
GTU60_RS11095	COG1006	Multisubunit Na H antiporter MnhC subunit
GTU60_RS11100	COG0651	ATP synthesis coupled electron transport
GTU60_RS11110	COG2212	antiporter activity
GTU60_RS11125	COG0477	Major facilitator Superfamily
GTU60_RS11150	COG3158	transport of potassium into the cell
GTU60_RS11155	COG0642	Histidine kinase
GTU60_RS11180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTU60_RS11185	COG4208	sulfate ABC transporter
GTU60_RS11190	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GTU60_RS11195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GTU60_RS11210	COG1234	tRNA 3'-trailer cleavage
GTU60_RS11215	COG1278	Cold shock
GTU60_RS11230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTU60_RS11230	COG1648	precorrin-2 dehydrogenase activity
GTU60_RS11235	COG2010	Cytochrome c
GTU60_RS11260	COG0535	radical SAM domain protein
GTU60_RS11265	COG1648	precorrin-2 dehydrogenase activity
GTU60_RS11265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTU60_RS11275	COG2010	Cytochrome c
GTU60_RS11280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS11285	COG0626	cystathionine gamma-synthase activity
GTU60_RS11290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTU60_RS11295	COG0557	exoribonuclease II activity
GTU60_RS11315	COG0765	amino acid transport
GTU60_RS11320	COG0765	amino acid transport
GTU60_RS11325	COG1126	abc transporter atp-binding protein
GTU60_RS11340	COG1850	ribulose-bisphosphate carboxylase activity
GTU60_RS11360	COG2375	cellular response to nickel ion
GTU60_RS11375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS11390	COG0583	DNA-binding transcription factor activity
GTU60_RS11395	COG3842	ATPase activity
GTU60_RS11400	COG1175	transmembrane transport
GTU60_RS11405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU60_RS11410	COG1840	ABC-type Fe3 transport system, periplasmic component
GTU60_RS11430	COG0412	Dienelactone hydrolase
GTU60_RS11435	COG3530	Putative quorum-sensing-regulated virulence factor
GTU60_RS11440	COG0625	glutathione transferase activity
GTU60_RS11445	COG1741	Belongs to the pirin family
GTU60_RS11455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU60_RS11460	COG2814	Major facilitator Superfamily
GTU60_RS11465	COG2807	transmembrane transport
GTU60_RS11470	COG2207	Transcriptional regulator
GTU60_RS11475	COG3135	benzoate transporter
GTU60_RS11500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GTU60_RS11510	COG0402	S-adenosylhomocysteine deaminase activity
GTU60_RS11520	COG0745	RESPONSE REGULATOR receiver
GTU60_RS11525	COG2205	protein histidine kinase activity
GTU60_RS11540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GTU60_RS11545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GTU60_RS11550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GTU60_RS11560	COG0330	HflC and HflK could
GTU60_RS11565	COG0330	HflC and HflK could
GTU60_RS11570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GTU60_RS11575	COG1923	regulation of RNA biosynthetic process
GTU60_RS11585	COG1160	GTP binding
GTU60_RS11590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU60_RS11595	COG2976	Protein conserved in bacteria
GTU60_RS11615	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GTU60_RS11620	COG0105	UTP biosynthetic process
GTU60_RS11630	COG0336	Belongs to the RNA methyltransferase TrmD family
GTU60_RS11640	COG0228	four-way junction DNA binding
GTU60_RS11645	COG0425	Belongs to the sulfur carrier protein TusA family
GTU60_RS11650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GTU60_RS11665	COG2351	hydroxyisourate hydrolase activity
GTU60_RS11700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS11725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GTU60_RS11730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GTU60_RS11755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTU60_RS11760	COG0601	transmembrane transport
GTU60_RS11790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GTU60_RS11795	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GTU60_RS11800	COG0542	response to heat
GTU60_RS11805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GTU60_RS11820	COG0348	domain, Protein
GTU60_RS11840	COG3278	Belongs to the heme-copper respiratory oxidase family
GTU60_RS11850	COG2217	Heavy metal translocating P-type atpase
GTU60_RS11855	COG2224	Isocitrate lyase
GTU60_RS11860	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTU60_RS11860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTU60_RS11880	COG1472	Belongs to the glycosyl hydrolase 3 family
GTU60_RS11885	COG0736	holo-[acyl-carrier-protein] synthase activity
GTU60_RS11895	COG2050	protein possibly involved in aromatic compounds catabolism
GTU60_RS11900	COG1024	Enoyl-CoA hydratase
GTU60_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS11910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTU60_RS11915	COG2151	metal-sulfur cluster biosynthetic enzyme
GTU60_RS11920	COG3396	Phenylacetate-CoA oxygenase
GTU60_RS11925	COG3460	Phenylacetate-CoA oxygenase
GTU60_RS11930	COG3396	Phenylacetate-CoA oxygenase
GTU60_RS11935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GTU60_RS11940	COG0501	Belongs to the peptidase M48B family
GTU60_RS11945	COG1162	GTPase activity
GTU60_RS11955	COG0335	large ribosomal subunit rRNA binding
GTU60_RS11975	COG0450	alkyl hydroperoxide reductase
GTU60_RS11980	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS11995	COG0123	including yeast histone deacetylase and acetoin utilization protein
GTU60_RS12000	COG2951	lytic endotransglycosylase activity
GTU60_RS12010	COG1596	polysaccharide export
GTU60_RS12010	COG1555	photosystem II stabilization
GTU60_RS12015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU60_RS12020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GTU60_RS12025	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GTU60_RS12045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GTU60_RS12050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GTU60_RS12055	COG0287	Prephenate dehydrogenase
GTU60_RS12065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GTU60_RS12080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTU60_RS12100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GTU60_RS12110	COG4771	TonB-dependent receptor
GTU60_RS12125	COG0753	catalase activity
GTU60_RS12135	COG4335	DNA alkylation repair
GTU60_RS12145	COG0436	Aminotransferase
GTU60_RS12155	COG0251	oxidation-reduction process
GTU60_RS12160	COG1309	transcriptional regulator
GTU60_RS12170	COG0488	(ABC) transporter
GTU60_RS12220	COG0625	glutathione transferase activity
GTU60_RS12230	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GTU60_RS12235	COG1280	lysine exporter protein (LysE YggA)
GTU60_RS12255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTU60_RS12265	COG2205	protein histidine kinase activity
GTU60_RS12265	COG2198	Histidine kinase
GTU60_RS12265	COG0784	Response regulator, receiver
GTU60_RS12270	COG2046	Belongs to the sulfate adenylyltransferase family
GTU60_RS12275	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GTU60_RS12280	COG0642	Histidine kinase
GTU60_RS12290	COG0840	transmembrane signaling receptor activity
GTU60_RS12295	COG2119	membrane
GTU60_RS12310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GTU60_RS12315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GTU60_RS12330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GTU60_RS12335	COG2321	neutral zinc metallopeptidase
GTU60_RS12350	COG2175	clavaminate synthase activity
GTU60_RS12355	COG1846	Transcriptional regulator
GTU60_RS12360	COG0347	Belongs to the P(II) protein family
GTU60_RS12365	COG0004	ammonium transporteR
GTU60_RS12370	COG3909	cytochrome
GTU60_RS12380	COG0625	glutathione transferase activity
GTU60_RS12390	COG0657	acetylesterase activity
GTU60_RS12395	COG0730	response to heat
GTU60_RS12400	COG0482	sulfurtransferase activity
GTU60_RS12405	COG0277	FAD linked oxidase domain protein
GTU60_RS12410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTU60_RS12415	COG2879	small protein
GTU60_RS12420	COG1966	Carbon starvation protein
GTU60_RS12425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS12430	COG0765	amino acid transport
GTU60_RS12435	COG0765	amino acid transport
GTU60_RS12440	COG1126	abc transporter atp-binding protein
GTU60_RS12445	COG0028	Belongs to the TPP enzyme family
GTU60_RS12450	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS12455	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GTU60_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS12470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS12475	COG1116	anion transmembrane transporter activity
GTU60_RS12490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS12505	COG5285	phytanoyl-CoA dioxygenase
GTU60_RS12510	COG0662	Cupin 2, conserved barrel domain protein
GTU60_RS12520	COG0456	acetyltransferase
GTU60_RS12525	COG1846	Transcriptional regulator
GTU60_RS12535	COG0312	modulator of DNA gyrase
GTU60_RS12550	COG0308	aminopeptidase N
GTU60_RS12555	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GTU60_RS12570	COG0473	3-isopropylmalate dehydrogenase activity
GTU60_RS12580	COG0433	COG0433 Predicted ATPase
GTU60_RS12585	COG0217	transcriptional regulatory protein
GTU60_RS12590	COG0151	Belongs to the GarS family
GTU60_RS12600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GTU60_RS12605	COG0799	negative regulation of ribosome biogenesis
GTU60_RS12610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GTU60_RS12615	COG0424	maF-like protein
GTU60_RS12645	COG2084	Dehydrogenase
GTU60_RS12650	COG0625	glutathione transferase activity
GTU60_RS12655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GTU60_RS12660	COG1047	Peptidyl-prolyl cis-trans
GTU60_RS12665	COG2003	Belongs to the UPF0758 family
GTU60_RS12670	COG1737	Transcriptional regulator
GTU60_RS12675	COG0477	Major facilitator Superfamily
GTU60_RS12685	COG2271	Major facilitator Superfamily
GTU60_RS12700	COG0534	Mate efflux family protein
GTU60_RS12705	COG4175	Glycine betaine
GTU60_RS12710	COG4176	ABC-type proline glycine betaine transport system permease component
GTU60_RS12720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTU60_RS12725	COG2814	Major facilitator Superfamily
GTU60_RS12730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GTU60_RS12735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GTU60_RS12740	COG0495	leucyl-tRNA aminoacylation
GTU60_RS12750	COG1466	dna polymerase III delta subunit
GTU60_RS12755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GTU60_RS12760	COG1981	membrane
GTU60_RS12775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GTU60_RS12785	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GTU60_RS12790	COG0148	phosphopyruvate hydratase activity
GTU60_RS12800	COG2814	Major facilitator Superfamily
GTU60_RS12815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GTU60_RS12825	COG0504	CTP synthase activity
GTU60_RS12860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTU60_RS12870	COG0791	NLP P60 protein
GTU60_RS12880	COG0583	DNA-binding transcription factor activity
GTU60_RS12890	COG0583	DNA-binding transcription factor activity
GTU60_RS12900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTU60_RS12915	COG1045	serine acetyltransferase
GTU60_RS12930	COG1381	Involved in DNA repair and RecF pathway recombination
GTU60_RS12935	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GTU60_RS12940	COG0571	ribonuclease III activity
GTU60_RS12955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTU60_RS12975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTU60_RS12980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTU60_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS12990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GTU60_RS12995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTU60_RS13005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GTU60_RS13010	COG1399	metal-binding, possibly nucleic acid-binding protein
GTU60_RS13015	COG0424	maF-like protein
GTU60_RS13025	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTU60_RS13030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GTU60_RS13035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GTU60_RS13040	COG0546	phosphoglycolate phosphatase activity
GTU60_RS13045	COG0564	pseudouridine synthase activity
GTU60_RS13050	COG1530	ribonuclease E activity
GTU60_RS13055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GTU60_RS13060	COG0159	tryptophan synthase activity
GTU60_RS13065	COG0133	tryptophan synthase activity
GTU60_RS13070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTU60_RS13080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GTU60_RS13085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GTU60_RS13095	COG2878	Part of a membrane complex involved in electron transport
GTU60_RS13100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GTU60_RS13105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTU60_RS13110	COG3047	cAMP biosynthetic process
GTU60_RS13135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTU60_RS13140	COG2917	probably involved in intracellular septation
GTU60_RS13150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU60_RS13155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GTU60_RS13165	COG1196	nuclear chromosome segregation
GTU60_RS13175	COG1573	uracil-dna glycosylase
GTU60_RS13180	COG1214	PFAM Peptidase M22, glycoprotease
GTU60_RS13195	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GTU60_RS13200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GTU60_RS13205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GTU60_RS13210	COG0560	Phosphoserine phosphatase
GTU60_RS13225	COG1007	ATP synthesis coupled electron transport
GTU60_RS13240	COG0713	ATP synthesis coupled electron transport
GTU60_RS13250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU60_RS13255	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GTU60_RS13260	COG1034	ATP synthesis coupled electron transport
GTU60_RS13275	COG0649	NAD binding
GTU60_RS13280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU60_RS13285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU60_RS13290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTU60_RS13295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS13310	COG0149	triose-phosphate isomerase activity
GTU60_RS13315	COG0604	alcohol dehydrogenase
GTU60_RS13335	COG1185	polyribonucleotide nucleotidyltransferase activity
GTU60_RS13340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GTU60_RS13345	COG1183	phosphatidylcholine synthase activity
GTU60_RS13350	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GTU60_RS13355	COG0440	acetolactate synthase activity
GTU60_RS13360	COG0028	Belongs to the TPP enzyme family
GTU60_RS13365	COG1289	transmembrane transporter activity
GTU60_RS13370	COG3022	response to hydroperoxide
GTU60_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS13395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GTU60_RS13400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTU60_RS13405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GTU60_RS13410	COG1674	ftsk spoiiie
GTU60_RS13415	COG0492	ferredoxin-NADP+ reductase activity
GTU60_RS13435	COG0477	Major facilitator Superfamily
GTU60_RS13455	COG2272	Belongs to the type-B carboxylesterase lipase family
GTU60_RS13460	COG1960	acyl-CoA dehydrogenase activity
GTU60_RS13485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GTU60_RS13505	COG2204	response regulator
GTU60_RS13545	COG4964	Belongs to the GSP D family
GTU60_RS13600	COG0612	Peptidase, M16
GTU60_RS13605	COG0484	heat shock protein binding
GTU60_RS13610	COG0443	Heat shock 70 kDa protein
GTU60_RS13615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTU60_RS13620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GTU60_RS13625	COG1420	regulation of RNA biosynthetic process
GTU60_RS13635	COG0497	DNA recombination
GTU60_RS13640	COG0735	belongs to the Fur family
GTU60_RS13645	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTU60_RS13650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GTU60_RS13665	COG2267	carboxylic ester hydrolase activity
GTU60_RS13675	COG0477	Major facilitator Superfamily
GTU60_RS13685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GTU60_RS13720	COG1538	Outer membrane efflux protein
GTU60_RS13780	COG2814	Major facilitator Superfamily
GTU60_RS13790	COG2819	hydrolase of the alpha beta superfamily
GTU60_RS13810	COG1454	alcohol dehydrogenase
GTU60_RS13820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTU60_RS13845	COG1414	Transcriptional regulator
GTU60_RS13850	COG0513	Belongs to the DEAD box helicase family
GTU60_RS13860	COG0583	DNA-binding transcription factor activity
GTU60_RS13865	COG4638	Rieske (2fe-2S)
GTU60_RS13870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GTU60_RS13885	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTU60_RS13900	COG3971	2-oxopent-4-enoate hydratase activity
GTU60_RS13905	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GTU60_RS13910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTU60_RS13915	COG2814	Major facilitator Superfamily
GTU60_RS13930	COG0154	amidase activity
GTU60_RS13935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS13940	COG2814	Major facilitator Superfamily
GTU60_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS13975	COG0842	Transport permease protein
GTU60_RS13980	COG1129	ABC transporter
GTU60_RS13980	COG0842	Transport permease protein
GTU60_RS13985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU60_RS13995	COG3243	poly(R)-hydroxyalkanoic acid synthase
GTU60_RS14005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GTU60_RS14010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GTU60_RS14015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTU60_RS14030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTU60_RS14045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GTU60_RS14050	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GTU60_RS14060	COG0789	Transcriptional regulator
GTU60_RS14070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU60_RS14115	COG3278	Belongs to the heme-copper respiratory oxidase family
GTU60_RS14120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS14185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GTU60_RS14250	COG0517	IMP dehydrogenase activity
GTU60_RS14250	COG0516	GMP reductase activity
GTU60_RS14260	COG1027	Aspartate ammonia-lyase
GTU60_RS14265	COG1846	Transcriptional regulator
GTU60_RS14280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GTU60_RS14285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GTU60_RS14300	COG1414	Transcriptional regulator
GTU60_RS14320	COG0513	Belongs to the DEAD box helicase family
GTU60_RS14340	COG0429	hydrolase of the alpha beta-hydrolase fold
GTU60_RS14365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTU60_RS14375	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GTU60_RS14385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GTU60_RS14390	COG0632	four-way junction helicase activity
GTU60_RS14400	COG2255	four-way junction helicase activity
GTU60_RS14410	COG0418	dihydroorotase activity
GTU60_RS14420	COG0415	Belongs to the DNA photolyase family
GTU60_RS14485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTU60_RS14490	COG4654	Cytochrome c, class I
GTU60_RS14525	COG1177	transmembrane transport
GTU60_RS14530	COG3842	ATPase activity
GTU60_RS14535	COG1840	ABC-type Fe3 transport system, periplasmic component
GTU60_RS14540	COG2084	Dehydrogenase
GTU60_RS14555	COG0494	nUDIX hydrolase
GTU60_RS14560	COG0442	prolyl-tRNA aminoacylation
GTU60_RS14565	COG0824	Thioesterase
GTU60_RS14570	COG0811	peptide transport
GTU60_RS14585	COG0823	Involved in the tonB-independent uptake of proteins
GTU60_RS14600	COG0596	Alpha beta hydrolase
GTU60_RS14625	COG1079	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS14630	COG4603	Belongs to the binding-protein-dependent transport system permease family
GTU60_RS14635	COG3845	ABC transporter
GTU60_RS14655	COG0427	acetyl-CoA hydrolase
GTU60_RS14660	COG0583	DNA-binding transcription factor activity
GTU60_RS14665	COG3634	alkyl hydroperoxide reductase activity
GTU60_RS14680	COG0697	spore germination
GTU60_RS14685	COG0175	sulfate reduction
GTU60_RS14705	COG1012	belongs to the aldehyde dehydrogenase family
GTU60_RS14710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTU60_RS14715	COG5383	Protein conserved in bacteria
GTU60_RS14725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTU60_RS14740	COG0583	DNA-binding transcription factor activity
GTU60_RS14745	COG1741	Belongs to the pirin family
GTU60_RS14750	COG3706	GGDEF domain
GTU60_RS14755	COG0154	amidase activity
GTU60_RS14770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTU60_RS14780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GTU60_RS14785	COG0284	orotidine-5'-phosphate decarboxylase activity
GTU60_RS14800	COG1414	Transcriptional regulator
GTU60_RS14810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GTU60_RS14820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTU60_RS14825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GTU60_RS14850	COG0742	ribosomal rna small subunit methyltransferase
GTU60_RS14855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GTU60_RS14860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTU60_RS14890	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GTU60_RS14905	COG1335	isochorismatase
GTU60_RS14910	COG2309	aminopeptidase activity
GTU60_RS14915	COG0596	Alpha beta hydrolase
GTU60_RS14920	COG2010	Cytochrome c
GTU60_RS14920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GTU60_RS14925	COG2080	2 iron, 2 sulfur cluster binding
GTU60_RS14930	COG2010	Cytochrome c
GTU60_RS14930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GTU60_RS14940	COG0410	ABC transporter
GTU60_RS14945	COG0411	ABC transporter
GTU60_RS14985	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS15000	COG1234	tRNA 3'-trailer cleavage
GTU60_RS15005	COG2188	Transcriptional regulator
GTU60_RS15015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTU60_RS15025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GTU60_RS15025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GTU60_RS15030	COG3608	succinylglutamate desuccinylase aspartoacylase
GTU60_RS15030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GTU60_RS15035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTU60_RS15045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTU60_RS15075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS15100	COG1335	isochorismatase
GTU60_RS15105	COG2309	aminopeptidase activity
GTU60_RS15110	COG0596	Alpha beta hydrolase
GTU60_RS15125	COG1120	ATPase activity
GTU60_RS15130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTU60_RS15140	COG4206	TonB-dependent receptor
GTU60_RS15145	COG2031	fatty acid transporter
GTU60_RS15150	COG0583	DNA-binding transcription factor activity
GTU60_RS15155	COG0402	S-adenosylhomocysteine deaminase activity
GTU60_RS15160	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS15175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTU60_RS15180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTU60_RS15185	COG0328	RNA-DNA hybrid ribonuclease activity
GTU60_RS15190	COG2226	methyltransferase
GTU60_RS15195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTU60_RS15200	COG0741	lytic transglycosylase activity
GTU60_RS15200	COG1388	LysM domain
GTU60_RS15220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GTU60_RS15245	COG2204	response regulator
GTU60_RS15250	COG4191	Histidine kinase
GTU60_RS15255	COG1301	dicarboxylic acid transport
GTU60_RS15265	COG1054	Belongs to the UPF0176 family
GTU60_RS15290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTU60_RS15295	COG2204	response regulator
GTU60_RS15310	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GTU60_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS15330	COG1877	trehalose-phosphatase activity
GTU60_RS15365	COG0604	alcohol dehydrogenase
GTU60_RS15375	COG1024	Enoyl-CoA hydratase
GTU60_RS15395	COG1902	pentaerythritol trinitrate reductase activity
GTU60_RS15420	COG0583	DNA-binding transcription factor activity
GTU60_RS15425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTU60_RS15445	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GTU60_RS15450	COG0583	DNA-binding transcription factor activity
GTU60_RS15475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS15490	COG1393	Belongs to the ArsC family
GTU60_RS15495	COG0431	NADPH-dependent FMN reductase
GTU60_RS15500	COG0745	RESPONSE REGULATOR receiver
GTU60_RS15505	COG0642	Histidine kinase
GTU60_RS15520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTU60_RS15520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTU60_RS15525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GTU60_RS15530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTU60_RS15535	COG1881	PFAM PEBP family protein
GTU60_RS15540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GTU60_RS15545	COG0739	heme binding
GTU60_RS15550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GTU60_RS15555	COG0316	Belongs to the HesB IscA family
GTU60_RS15565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GTU60_RS15570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GTU60_RS15575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GTU60_RS15580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS15585	COG0312	modulator of DNA gyrase
GTU60_RS15590	COG3028	Belongs to the UPF0307 family
GTU60_RS15620	COG4566	intracellular signal transduction
GTU60_RS15625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTU60_RS15630	COG0402	S-adenosylhomocysteine deaminase activity
GTU60_RS15635	COG2233	PERMEase
GTU60_RS15640	COG2945	thiolester hydrolase activity
GTU60_RS15640	COG0596	Alpha beta hydrolase
GTU60_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS15660	COG0583	DNA-binding transcription factor activity
GTU60_RS15665	COG4681	YaeQ
GTU60_RS15690	COG0762	integral membrane protein
GTU60_RS15700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTU60_RS15700	COG2169	Transcriptional regulator
GTU60_RS15710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTU60_RS15725	COG0439	Biotin carboxylase
GTU60_RS15730	COG0511	ligase activity, forming carbon-carbon bonds
GTU60_RS15735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GTU60_RS15740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTU60_RS15745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTU60_RS15750	COG3150	esterase
GTU60_RS15765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTU60_RS15770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTU60_RS15780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GTU60_RS15795	COG1678	Uncharacterized ACR, COG1678
GTU60_RS15810	COG0352	thiamine-phosphate diphosphorylase activity
GTU60_RS15815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GTU60_RS15830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GTU60_RS15840	COG3237	CsbD-like
GTU60_RS15845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GTU60_RS15850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GTU60_RS15855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTU60_RS15860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GTU60_RS15885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GTU60_RS15900	COG1126	abc transporter atp-binding protein
GTU60_RS15905	COG0765	amino acid transport
GTU60_RS15910	COG4597	amino acid ABC transporter
GTU60_RS15915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTU60_RS15920	COG2884	Cell division ATP-binding protein ftsE
GTU60_RS15925	COG2177	Part of the ABC transporter FtsEX involved in
GTU60_RS15935	COG0772	Belongs to the SEDS family
GTU60_RS15940	COG0768	penicillin binding
GTU60_RS15950	COG1792	Involved in formation and maintenance of cell shape
GTU60_RS15955	COG1077	Cell shape determining protein MreB Mrl
GTU60_RS15960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GTU60_RS15965	COG0154	amidase activity
GTU60_RS15970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GTU60_RS15975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GTU60_RS15980	COG0583	DNA-binding transcription factor activity
GTU60_RS15985	COG2259	Doxx family
GTU60_RS15990	COG3384	dioxygenase
GTU60_RS16000	COG3245	cytochrome
GTU60_RS16015	COG3604	Transcriptional regulator
GTU60_RS16030	COG0786	glutamate:sodium symporter activity
GTU60_RS16035	COG0142	geranyltranstransferase activity
GTU60_RS16045	COG0494	nUDIX hydrolase
GTU60_RS16050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GTU60_RS16075	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GTU60_RS16080	COG0237	dephospho-CoA kinase activity
GTU60_RS16095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GTU60_RS16100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GTU60_RS16110	COG0477	Major facilitator Superfamily
GTU60_RS16140	COG4206	TonB-dependent receptor
GTU60_RS16145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GTU60_RS16155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTU60_RS16175	COG0598	Magnesium transport protein CorA
GTU60_RS16190	COG2022	thiamine diphosphate biosynthetic process
GTU60_RS16195	COG0351	phosphomethylpyrimidine kinase
GTU60_RS16200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTU60_RS16205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GTU60_RS16210	COG1538	Outer membrane efflux protein
GTU60_RS16215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GTU60_RS16225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GTU60_RS16240	COG2226	methyltransferase
GTU60_RS16245	COG0745	RESPONSE REGULATOR receiver
GTU60_RS16260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GTU60_RS16270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTU60_RS16275	COG1238	metal cluster binding
GTU60_RS16300	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTU60_RS16305	COG4988	ABC transporter
GTU60_RS16315	COG1294	oxidase, subunit
GTU60_RS16320	COG1271	oxidase subunit
GTU60_RS16335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GTU60_RS16350	COG1137	ATPase activity
GTU60_RS16360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTU60_RS16365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GTU60_RS16370	COG1660	Displays ATPase and GTPase activities
GTU60_RS16380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GTU60_RS16385	COG0792	nuclease activity
GTU60_RS16390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTU60_RS16405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTU60_RS16425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTU60_RS16430	COG0793	Belongs to the peptidase S41A family
GTU60_RS16440	COG0588	phosphoglycerate mutase activity
GTU60_RS16445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTU60_RS16455	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GTU60_RS16460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GTU60_RS16465	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS16470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GTU60_RS16475	COG1040	competence protein
GTU60_RS16480	COG2226	methyltransferase
GTU60_RS16485	COG4771	TonB-dependent receptor
GTU60_RS16490	COG0745	RESPONSE REGULATOR receiver
GTU60_RS16505	COG2204	response regulator
GTU60_RS16525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTU60_RS16535	COG3473	Maleate cis-trans isomerase
GTU60_RS16550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GTU60_RS16580	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GTU60_RS16580	COG0662	Cupin 2, conserved barrel domain protein
GTU60_RS16585	COG1215	transferase activity, transferring glycosyl groups
GTU60_RS16595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GTU60_RS16610	COG1088	dTDP-glucose 4,6-dehydratase activity
GTU60_RS16615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GTU60_RS16630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GTU60_RS16640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GTU60_RS16645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GTU60_RS16650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GTU60_RS16665	COG0356	it plays a direct role in the translocation of protons across the membrane
GTU60_RS16675	COG1024	Enoyl-CoA hydratase
GTU60_RS16690	COG0037	tRNA processing
GTU60_RS16695	COG0163	prenyltransferase activity
GTU60_RS16700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GTU60_RS16705	COG2890	protein-(glutamine-N5) methyltransferase activity
GTU60_RS16755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTU60_RS16800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GTU60_RS16805	COG2264	protein methyltransferase activity
GTU60_RS16810	COG4773	Receptor
GTU60_RS16835	COG3180	Ammonia monooxygenase
GTU60_RS16855	COG5002	protein histidine kinase activity
GTU60_RS16870	COG0477	Major facilitator Superfamily
GTU60_RS16875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU60_RS16895	COG1116	anion transmembrane transporter activity
GTU60_RS16925	COG0437	4 iron, 4 sulfur cluster binding
GTU60_RS16930	COG2864	formate dehydrogenase
GTU60_RS16940	COG1921	L-seryl-tRNASec selenium transferase activity
GTU60_RS16945	COG3276	selenocysteine insertion sequence binding
GTU60_RS16955	COG1476	TRANSCRIPTIONal
GTU60_RS16970	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS16990	COG0709	Synthesizes selenophosphate from selenide and ATP
GTU60_RS17005	COG0583	DNA-binding transcription factor activity
GTU60_RS17010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GTU60_RS17015	COG3901	Regulator of nitric oxide reductase transcription
GTU60_RS17015	COG0348	domain, Protein
GTU60_RS17020	COG4263	nitrous-oxide reductase activity
GTU60_RS17035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GTU60_RS17050	COG0166	Belongs to the GPI family
GTU60_RS17070	COG1215	transferase activity, transferring glycosyl groups
GTU60_RS17110	COG0438	transferase activity, transferring glycosyl groups
GTU60_RS17120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTU60_RS17155	COG0156	8-amino-7-oxononanoate synthase activity
GTU60_RS17160	COG3321	synthase
GTU60_RS17160	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS17160	COG0604	alcohol dehydrogenase
GTU60_RS17165	COG2233	PERMEase
GTU60_RS17170	COG0697	spore germination
GTU60_RS17175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS17180	COG0697	spore germination
GTU60_RS17200	COG2885	chlorophyll binding
GTU60_RS17295	COG0183	Belongs to the thiolase family
GTU60_RS17300	COG1024	Enoyl-CoA hydratase
GTU60_RS17300	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTU60_RS17315	COG1127	ABC transporter
GTU60_RS17320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTU60_RS17325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTU60_RS17340	COG1131	(ABC) transporter
GTU60_RS17345	COG0842	Transport permease protein
GTU60_RS17355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GTU60_RS17365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GTU60_RS17370	COG0131	Imidazoleglycerol-phosphate dehydratase
GTU60_RS17380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GTU60_RS17385	COG0107	imidazoleglycerol-phosphate synthase activity
GTU60_RS17395	COG0140	phosphoribosyl-ATP diphosphatase activity
GTU60_RS17400	COG0537	adenosine 5'-monophosphoramidase activity
GTU60_RS17405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTU60_RS17410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTU60_RS17420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTU60_RS17430	COG1970	mechanosensitive ion channel activity
GTU60_RS17435	COG0723	plastoquinol--plastocyanin reductase activity
GTU60_RS17440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GTU60_RS17445	COG2857	Cytochrome c1
GTU60_RS17450	COG0625	glutathione transferase activity
GTU60_RS17455	COG2969	positive regulation of protein catabolic process
GTU60_RS17460	COG4208	sulfate ABC transporter
GTU60_RS17465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GTU60_RS17470	COG4150	thiosulfate binding
GTU60_RS17490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTU60_RS17510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTU60_RS17515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTU60_RS17525	COG2084	Dehydrogenase
GTU60_RS17530	COG0129	dihydroxy-acid dehydratase activity
GTU60_RS17535	COG1802	Transcriptional regulator
GTU60_RS17540	COG1522	sequence-specific DNA binding
GTU60_RS17550	COG3483	tryptophan 2,3-dioxygenase activity
GTU60_RS17570	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GTU60_RS17575	COG0656	L-ascorbic acid biosynthetic process
GTU60_RS17585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GTU60_RS17590	COG3706	GGDEF domain
GTU60_RS17595	COG2226	methyltransferase
GTU60_RS17605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTU60_RS17620	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GTU60_RS17625	COG0583	DNA-binding transcription factor activity
GTU60_RS17630	COG0477	Major facilitator Superfamily
GTU60_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
GTU60_RS17645	COG1335	isochorismatase
GTU60_RS17665	COG2823	Periplasmic or secreted lipoprotein
GTU60_RS17675	COG3284	Transcriptional regulator
GTU60_RS17705	COG1595	DNA-templated transcription, initiation
GTU60_RS17715	COG1522	sequence-specific DNA binding
GTU60_RS17725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTU60_RS17745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GTU60_RS17780	COG0109	protoheme IX farnesyltransferase activity
GTU60_RS17800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTU60_RS17820	COG3568	Endonuclease Exonuclease Phosphatase
GTU60_RS17825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GTU60_RS17850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTU60_RS17860	COG1228	amidohydrolase
GTU60_RS17870	COG2986	histidine ammonia-lyase
GTU60_RS17875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GTU60_RS17905	COG2814	Major facilitator Superfamily
GTU60_RS17915	COG0789	Transcriptional regulator
GTU60_RS17945	COG0625	glutathione transferase activity
GTU60_RS17975	COG2365	Tyrosine phosphatase family
GTU60_RS17980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GTU60_RS18000	COG2423	ornithine cyclodeaminase activity
GTU60_RS18050	COG3069	C4-dicarboxylate transmembrane transporter activity
GTU60_RS18060	COG1802	Transcriptional regulator
GTU60_RS18070	COG2814	Major facilitator Superfamily
GTU60_RS18085	COG2814	Major facilitator Superfamily
GTU60_RS18090	COG0251	oxidation-reduction process
GTU60_RS18095	COG3181	Tripartite tricarboxylate transporter family receptor
GTU60_RS18100	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTU60_RS18105	COG1802	Transcriptional regulator
GTU60_RS18110	COG1595	DNA-templated transcription, initiation
GTU60_RS18115	COG3712	iron ion homeostasis
GTU60_RS18130	COG2814	Major facilitator Superfamily
GTU60_RS18140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTU60_RS18145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GTU60_RS18150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTU60_RS18170	COG5001	Diguanylate cyclase
GTU60_RS18170	COG5002	protein histidine kinase activity
GTU60_RS18175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTU60_RS18180	COG1333	cytochrome c biogenesis protein
GTU60_RS18190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GTU60_RS18195	COG0113	porphobilinogen synthase activity
GTU60_RS18200	COG4232	protein-disulfide reductase activity
GTU60_RS18220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTU60_RS18225	COG0203	ribosomal protein L17
GTU60_RS18230	COG0202	RNA polymerase activity
GTU60_RS18235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GTU60_RS18240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GTU60_RS18245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTU60_RS18250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTU60_RS18260	COG0201	protein transport
GTU60_RS18265	COG0200	Binds to the 23S rRNA
GTU60_RS18270	COG1841	ribosomal large subunit assembly
GTU60_RS18275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GTU60_RS18280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GTU60_RS18285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GTU60_RS18290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GTU60_RS18295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GTU60_RS18300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTU60_RS18305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GTU60_RS18310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome