locus-tag	class	description
NBV64_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBV64_RS00010	COG0592	DNA-directed DNA polymerase activity
NBV64_RS00060	COG1187	pseudouridine synthase activity
NBV64_RS00075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS00100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBV64_RS00105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBV64_RS00120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBV64_RS00125	COG3383	formate dehydrogenase (NAD+) activity
NBV64_RS00135	COG2186	Transcriptional regulator
NBV64_RS00140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS00160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NBV64_RS00165	COG0583	DNA-binding transcription factor activity
NBV64_RS00175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS00185	COG0559	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS00200	COG0318	PFAM AMP-dependent synthetase and ligase
NBV64_RS00210	COG0508	dehydrogenase complex catalyzes the overall conversion of
NBV64_RS00210	COG0596	Alpha beta hydrolase
NBV64_RS00215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS00230	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS00240	COG0697	spore germination
NBV64_RS00245	COG0583	DNA-binding transcription factor activity
NBV64_RS00255	COG3842	ATPase activity
NBV64_RS00265	COG0436	Aminotransferase
NBV64_RS00275	COG0523	cobalamin synthesis protein
NBV64_RS00330	COG1846	Transcriptional regulator
NBV64_RS00350	COG0179	Fumarylacetoacetate (FAA) hydrolase
NBV64_RS00355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBV64_RS00360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NBV64_RS00370	COG4638	Rieske (2fe-2S)
NBV64_RS00435	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS00445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NBV64_RS00460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NBV64_RS00490	COG1595	DNA-templated transcription, initiation
NBV64_RS00495	COG4608	Belongs to the ABC transporter superfamily
NBV64_RS00500	COG0444	Belongs to the ABC transporter superfamily
NBV64_RS00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBV64_RS00510	COG0601	transmembrane transport
NBV64_RS00520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NBV64_RS00525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NBV64_RS00540	COG1464	Belongs to the NlpA lipoprotein family
NBV64_RS00545	COG1464	Belongs to the NlpA lipoprotein family
NBV64_RS00550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBV64_RS00555	COG2011	ABC-type metal ion transport system permease component
NBV64_RS00580	COG1464	Belongs to the NlpA lipoprotein family
NBV64_RS00590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NBV64_RS00610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NBV64_RS00615	COG0431	NADPH-dependent FMN reductase
NBV64_RS00640	COG4149	molybdate abc transporter
NBV64_RS00650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NBV64_RS00655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBV64_RS00665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NBV64_RS00685	COG0028	Belongs to the TPP enzyme family
NBV64_RS00690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NBV64_RS00720	COG2922	Belongs to the Smg family
NBV64_RS00735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NBV64_RS00740	COG0183	Belongs to the thiolase family
NBV64_RS00745	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NBV64_RS00750	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS00780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NBV64_RS00790	COG0018	arginyl-trna synthetase
NBV64_RS00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NBV64_RS00830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NBV64_RS00835	COG0066	3-isopropylmalate dehydratase activity
NBV64_RS00840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NBV64_RS00845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NBV64_RS00850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NBV64_RS00855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS00855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NBV64_RS00865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS00870	COG1335	isochorismatase
NBV64_RS00875	COG0583	DNA-binding transcription factor activity
NBV64_RS00895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NBV64_RS00900	COG1280	lysine exporter protein (LysE YggA)
NBV64_RS00905	COG0513	Belongs to the DEAD box helicase family
NBV64_RS00915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NBV64_RS00930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBV64_RS00945	COG0154	amidase activity
NBV64_RS00960	COG0583	DNA-binding transcription factor activity
NBV64_RS00990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NBV64_RS00995	COG1127	ABC transporter
NBV64_RS01015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBV64_RS01020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NBV64_RS01030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS01055	COG0583	DNA-binding transcription factor activity
NBV64_RS01075	COG3093	addiction module antidote protein HigA
NBV64_RS01090	COG1254	Belongs to the acylphosphatase family
NBV64_RS01100	COG2358	TRAP transporter, solute receptor (TAXI family
NBV64_RS01110	COG0564	pseudouridine synthase activity
NBV64_RS01115	COG0252	asparaginase activity
NBV64_RS01140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NBV64_RS01145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NBV64_RS01150	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS01170	COG0559	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS01195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS01210	COG0758	DNA mediated transformation
NBV64_RS01215	COG0242	peptide deformylase activity
NBV64_RS01220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBV64_RS01225	COG0697	spore germination
NBV64_RS01255	COG4336	lyase activity
NBV64_RS01260	COG0583	DNA-binding transcription factor activity
NBV64_RS01265	COG0859	PFAM glycosyl transferase family 9
NBV64_RS01275	COG1278	Cold shock
NBV64_RS01280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NBV64_RS01285	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NBV64_RS01290	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NBV64_RS01290	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NBV64_RS01300	COG1686	Belongs to the peptidase S11 family
NBV64_RS01310	COG2921	Belongs to the UPF0250 family
NBV64_RS01315	COG0321	lipoyl(octanoyl) transferase activity
NBV64_RS01320	COG1024	Enoyl-CoA hydratase
NBV64_RS01325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NBV64_RS01335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBV64_RS01380	COG0826	peptidase U32
NBV64_RS01390	COG3154	lipid carrier protein
NBV64_RS01415	COG0134	indole-3-glycerol-phosphate synthase activity
NBV64_RS01420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NBV64_RS01425	COG0512	Glutamine amidotransferase of anthranilate synthase
NBV64_RS01475	COG0629	single-stranded DNA binding
NBV64_RS01485	COG0270	DNA (cytosine-5-)-methyltransferase activity
NBV64_RS01710	COG2003	Belongs to the UPF0758 family
NBV64_RS01770	COG0583	DNA-binding transcription factor activity
NBV64_RS01780	COG2207	Transcriptional regulator
NBV64_RS01810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NBV64_RS01815	COG2223	nitrite transmembrane transporter activity
NBV64_RS01825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NBV64_RS01830	COG3383	formate dehydrogenase (NAD+) activity
NBV64_RS01845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBV64_RS01850	COG4654	Cytochrome c, class I
NBV64_RS01860	COG1965	Belongs to the frataxin family
NBV64_RS01875	COG1116	anion transmembrane transporter activity
NBV64_RS01875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NBV64_RS01885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBV64_RS01890	COG0281	malic enzyme
NBV64_RS01890	COG0280	phosphate acetyltransferase
NBV64_RS01905	COG2814	Major facilitator Superfamily
NBV64_RS01910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBV64_RS01915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NBV64_RS01935	COG1294	oxidase, subunit
NBV64_RS01940	COG1271	oxidase subunit
NBV64_RS01955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS01970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NBV64_RS01975	COG0109	protoheme IX farnesyltransferase activity
NBV64_RS01980	COG1999	signal sequence binding
NBV64_RS01985	COG0583	DNA-binding transcription factor activity
NBV64_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS02030	COG0582	viral genome integration into host DNA
NBV64_RS02040	COG0546	phosphoglycolate phosphatase activity
NBV64_RS02050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NBV64_RS02055	COG2967	ApaG domain
NBV64_RS02060	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NBV64_RS02065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBV64_RS02070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NBV64_RS02080	COG0840	transmembrane signaling receptor activity
NBV64_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS02095	COG1535	isochorismatase
NBV64_RS02095	COG3433	isochorismatase activity
NBV64_RS02100	COG1169	isochorismate synthase
NBV64_RS02115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NBV64_RS02120	COG1535	isochorismatase
NBV64_RS02120	COG3433	isochorismatase activity
NBV64_RS02125	COG1021	2,3-dihydroxybenzoate-AMP ligase
NBV64_RS02155	COG0683	leucine binding
NBV64_RS02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NBV64_RS02185	COG1250	3-hydroxyacyl-CoA dehydrogenase
NBV64_RS02205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NBV64_RS02210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBV64_RS02220	COG0513	Belongs to the DEAD box helicase family
NBV64_RS02225	COG2814	Major facilitator Superfamily
NBV64_RS02235	COG0583	DNA-binding transcription factor activity
NBV64_RS02245	COG1253	flavin adenine dinucleotide binding
NBV64_RS02270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBV64_RS02280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NBV64_RS02295	COG2311	Membrane
NBV64_RS02310	COG0456	acetyltransferase
NBV64_RS02330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NBV64_RS02345	COG0402	S-adenosylhomocysteine deaminase activity
NBV64_RS02350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NBV64_RS02355	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NBV64_RS02365	COG0583	DNA-binding transcription factor activity
NBV64_RS02370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS02375	COG1126	abc transporter atp-binding protein
NBV64_RS02380	COG0765	amino acid transport
NBV64_RS02385	COG0765	amino acid transport
NBV64_RS02390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBV64_RS02400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NBV64_RS02415	COG3391	amine dehydrogenase activity
NBV64_RS02425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NBV64_RS02450	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NBV64_RS02455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBV64_RS02460	COG0210	DNA helicase
NBV64_RS02475	COG0067	glutamate synthase
NBV64_RS02475	COG0069	glutamate synthase activity
NBV64_RS02475	COG0070	glutamate synthase
NBV64_RS02480	COG1024	Enoyl-CoA hydratase
NBV64_RS02490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NBV64_RS02495	COG1250	3-hydroxyacyl-CoA dehydrogenase
NBV64_RS02525	COG2918	glutathione biosynthetic process
NBV64_RS02540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NBV64_RS02550	COG2223	nitrite transmembrane transporter activity
NBV64_RS02555	COG2860	membrane
NBV64_RS02560	COG1346	cytolysis
NBV64_RS02575	COG0251	oxidation-reduction process
NBV64_RS02615	COG1280	lysine exporter protein (LysE YggA)
NBV64_RS02625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBV64_RS02640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NBV64_RS02655	COG2096	Adenosyltransferase
NBV64_RS02670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NBV64_RS02675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NBV64_RS02685	COG0523	cobalamin synthesis protein
NBV64_RS02690	COG0735	belongs to the Fur family
NBV64_RS02700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NBV64_RS02705	COG0803	Belongs to the bacterial solute-binding protein 9 family
NBV64_RS02710	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NBV64_RS02720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBV64_RS02725	COG1560	Kdo2-lipid A biosynthetic process
NBV64_RS02735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NBV64_RS02740	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NBV64_RS02745	COG1950	PFAM Membrane protein of
NBV64_RS02780	COG0275	rRNA processing
NBV64_RS02785	COG0730	response to heat
NBV64_RS02790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NBV64_RS02795	COG0129	dihydroxy-acid dehydratase activity
NBV64_RS02805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NBV64_RS02815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NBV64_RS02815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS02830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NBV64_RS02835	COG0628	permease
NBV64_RS02870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBV64_RS02885	COG3685	Protein conserved in bacteria
NBV64_RS02905	COG1846	Transcriptional regulator
NBV64_RS02920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBV64_RS02940	COG4774	siderophore transport
NBV64_RS02945	COG4607	ABC-type enterochelin transport system periplasmic component
NBV64_RS02950	COG4604	ABC transporter, ATP-binding protein
NBV64_RS02955	COG4605	iron ion homeostasis
NBV64_RS02960	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBV64_RS02970	COG1132	(ABC) transporter
NBV64_RS02970	COG2375	cellular response to nickel ion
NBV64_RS02975	COG0277	FAD linked oxidase domain protein
NBV64_RS02980	COG1304	FMN binding
NBV64_RS02985	COG2186	Transcriptional regulator
NBV64_RS03005	COG1609	Transcriptional regulator
NBV64_RS03010	COG1522	sequence-specific DNA binding
NBV64_RS03015	COG3844	kynureninase activity
NBV64_RS03020	COG1113	amino acid transport
NBV64_RS03050	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS03055	COG1349	DNA-binding transcription factor activity
NBV64_RS03075	COG0395	ABC-type sugar transport system, permease component
NBV64_RS03100	COG0861	Integral membrane protein TerC family
NBV64_RS03105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBV64_RS03115	COG1671	Belongs to the UPF0178 family
NBV64_RS03125	COG1418	mRNA catabolic process
NBV64_RS03135	COG4948	Mandelate Racemase Muconate Lactonizing
NBV64_RS03145	COG0477	Major facilitator Superfamily
NBV64_RS03160	COG0154	amidase activity
NBV64_RS03170	COG0583	DNA-binding transcription factor activity
NBV64_RS03195	COG0326	Molecular chaperone. Has ATPase activity
NBV64_RS03200	COG4774	siderophore transport
NBV64_RS03205	COG3128	pkhd-type hydroxylase
NBV64_RS03215	COG3023	N-Acetylmuramoyl-L-alanine amidase
NBV64_RS03230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBV64_RS03235	COG1652	LysM domain
NBV64_RS03250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NBV64_RS03270	COG3433	isochorismatase activity
NBV64_RS03270	COG1535	isochorismatase
NBV64_RS03295	COG0583	DNA-binding transcription factor activity
NBV64_RS03305	COG0387	Pfam Sodium calcium exchanger
NBV64_RS03320	COG0477	Major facilitator Superfamily
NBV64_RS03325	COG0235	Class ii aldolase
NBV64_RS03340	COG3391	amine dehydrogenase activity
NBV64_RS03345	COG0590	tRNA wobble adenosine to inosine editing
NBV64_RS03350	COG3257	ureidoglycine aminohydrolase activity
NBV64_RS03355	COG0583	DNA-binding transcription factor activity
NBV64_RS03360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBV64_RS03365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBV64_RS03365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBV64_RS03375	COG0489	protein tyrosine kinase activity
NBV64_RS03400	COG2081	HI0933 family
NBV64_RS03405	COG0509	glycine decarboxylation via glycine cleavage system
NBV64_RS03415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBV64_RS03420	COG1765	OsmC-like protein
NBV64_RS03425	COG3278	Belongs to the heme-copper respiratory oxidase family
NBV64_RS03450	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NBV64_RS03455	COG0469	pyruvate kinase activity
NBV64_RS03460	COG3193	protein, possibly involved in utilization of glycolate and propanediol
NBV64_RS03470	COG2084	Dehydrogenase
NBV64_RS03475	COG3622	Belongs to the hyi family
NBV64_RS03480	COG3960	tartronate-semialdehyde synthase activity
NBV64_RS03485	COG0583	DNA-binding transcription factor activity
NBV64_RS03495	COG2233	PERMEase
NBV64_RS03500	COG1942	4-Oxalocrotonate Tautomerase
NBV64_RS03505	COG0235	Class ii aldolase
NBV64_RS03510	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NBV64_RS03515	COG3648	Uricase
NBV64_RS03515	COG3195	allantoin biosynthetic process
NBV64_RS03525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBV64_RS03530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NBV64_RS03545	COG0438	transferase activity, transferring glycosyl groups
NBV64_RS03550	COG0438	transferase activity, transferring glycosyl groups
NBV64_RS03555	COG0438	transferase activity, transferring glycosyl groups
NBV64_RS03565	COG0277	FAD linked oxidase domain protein
NBV64_RS03575	COG0179	Fumarylacetoacetate (FAA) hydrolase
NBV64_RS03580	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NBV64_RS03590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBV64_RS03600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NBV64_RS03610	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NBV64_RS03625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBV64_RS03630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NBV64_RS03635	COG0193	aminoacyl-tRNA hydrolase activity
NBV64_RS03645	COG0012	GTP binding
NBV64_RS03665	COG0488	(ABC) transporter
NBV64_RS03680	COG0288	reversible hydration of carbon dioxide
NBV64_RS03685	COG0583	DNA-binding transcription factor activity
NBV64_RS03705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NBV64_RS03715	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NBV64_RS03725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NBV64_RS03730	COG3088	subunit of a heme lyase
NBV64_RS03735	COG4235	cytochrome complex assembly
NBV64_RS03740	COG0785	Cytochrome C biogenesis protein
NBV64_RS03750	COG2169	Transcriptional regulator
NBV64_RS03750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NBV64_RS03770	COG0559	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS03780	COG0411	ABC transporter
NBV64_RS03790	COG1858	cytochrome C peroxidase
NBV64_RS03795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NBV64_RS03800	COG1959	2 iron, 2 sulfur cluster binding
NBV64_RS03805	COG2346	COG2346, Truncated hemoglobins
NBV64_RS03810	COG0463	Glycosyl transferase, family 2
NBV64_RS03850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NBV64_RS03855	COG3383	formate dehydrogenase (NAD+) activity
NBV64_RS03870	COG1910	domain protein
NBV64_RS03875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NBV64_RS03880	COG0746	molybdenum cofactor guanylyltransferase activity
NBV64_RS03885	COG0303	'Molybdopterin
NBV64_RS03890	COG0521	Mo-molybdopterin cofactor biosynthetic process
NBV64_RS03895	COG0314	molybdopterin synthase activity
NBV64_RS03905	COG0315	cyclic pyranopterin monophosphate synthase activity
NBV64_RS03935	COG0678	peroxiredoxin activity
NBV64_RS03950	COG0697	spore germination
NBV64_RS03955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NBV64_RS03985	COG2814	Major facilitator Superfamily
NBV64_RS04025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NBV64_RS04030	COG4535	Mg2 and Co2 transporter CorC
NBV64_RS04035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBV64_RS04040	COG1702	phosphate starvation-inducible protein PhoH
NBV64_RS04045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NBV64_RS04055	COG0024	Methionine aminopeptidase
NBV64_RS04060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBV64_RS04065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBV64_RS04070	COG1862	Preprotein translocase
NBV64_RS04075	COG0343	queuine tRNA-ribosyltransferase activity
NBV64_RS04080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NBV64_RS04085	COG2027	D-alanyl-D-alanine carboxypeptidase
NBV64_RS04090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBV64_RS04100	COG4575	ribosome binding
NBV64_RS04115	COG0583	DNA-binding transcription factor activity
NBV64_RS04130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NBV64_RS04145	COG0154	amidase activity
NBV64_RS04155	COG0477	Major facilitator Superfamily
NBV64_RS04170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NBV64_RS04180	COG0436	Aminotransferase
NBV64_RS04190	COG0281	malic enzyme
NBV64_RS04190	COG0280	phosphate acetyltransferase
NBV64_RS04200	COG2732	(Barnase) inhibitor
NBV64_RS04205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NBV64_RS04210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NBV64_RS04215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NBV64_RS04220	COG0126	phosphoglycerate kinase activity
NBV64_RS04240	COG0521	Mo-molybdopterin cofactor biosynthetic process
NBV64_RS04250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NBV64_RS04255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBV64_RS04260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBV64_RS04265	COG0009	L-threonylcarbamoyladenylate synthase
NBV64_RS04270	COG0596	Alpha beta hydrolase
NBV64_RS04275	COG1012	belongs to the aldehyde dehydrogenase family
NBV64_RS04275	COG2030	dehydratase
NBV64_RS04280	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS04290	COG0405	Gamma-glutamyltransferase
NBV64_RS04300	COG0579	oxidoreductase
NBV64_RS04305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NBV64_RS04310	COG0259	pyridoxamine-phosphate oxidase activity
NBV64_RS04320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NBV64_RS04335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NBV64_RS04340	COG1215	transferase activity, transferring glycosyl groups
NBV64_RS04350	COG0488	(ABC) transporter
NBV64_RS04370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NBV64_RS04375	COG2894	cell division
NBV64_RS04385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBV64_RS04390	COG1271	oxidase subunit
NBV64_RS04395	COG1294	oxidase, subunit
NBV64_RS04400	COG0038	chloride channel
NBV64_RS04410	COG0514	ATP-dependent DNA helicase (RecQ)
NBV64_RS04415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBV64_RS04420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBV64_RS04425	COG0633	Ferredoxin
NBV64_RS04430	COG0488	(ABC) transporter
NBV64_RS04440	COG2001	Belongs to the MraZ family
NBV64_RS04445	COG0275	rRNA processing
NBV64_RS04450	COG3116	cell division
NBV64_RS04460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBV64_RS04465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBV64_RS04470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBV64_RS04480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBV64_RS04485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NBV64_RS04490	COG1181	Belongs to the D-alanine--D-alanine ligase family
NBV64_RS04495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NBV64_RS04510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NBV64_RS04520	COG1196	nuclear chromosome segregation
NBV64_RS04520	COG0739	heme binding
NBV64_RS04520	COG0741	lytic transglycosylase activity
NBV64_RS04525	COG0653	protein targeting
NBV64_RS04535	COG2239	Acts as a magnesium transporter
NBV64_RS04545	COG1473	amidohydrolase
NBV64_RS04550	COG0318	PFAM AMP-dependent synthetase and ligase
NBV64_RS04560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NBV64_RS04560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBV64_RS04575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBV64_RS04580	COG2011	ABC-type metal ion transport system permease component
NBV64_RS04590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS04595	COG0765	amino acid transport
NBV64_RS04600	COG1126	abc transporter atp-binding protein
NBV64_RS04610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NBV64_RS04625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBV64_RS04630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NBV64_RS04635	COG0700	Nucleoside recognition
NBV64_RS04650	COG0204	Acyl-transferase
NBV64_RS04655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NBV64_RS04660	COG0751	glycine-tRNA ligase activity
NBV64_RS04665	COG0752	glycyl-tRNA synthetase alpha subunit
NBV64_RS04685	COG1309	transcriptional regulator
NBV64_RS04700	COG2814	Major facilitator Superfamily
NBV64_RS04715	COG1573	uracil-dna glycosylase
NBV64_RS04720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NBV64_RS04725	COG0617	tRNA 3'-terminal CCA addition
NBV64_RS04735	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBV64_RS04740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NBV64_RS04745	COG1953	Uracil, thiamine, allantoin
NBV64_RS04750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBV64_RS04755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBV64_RS04760	COG0586	Pfam SNARE associated Golgi protein
NBV64_RS04765	COG0860	N-Acetylmuramoyl-L-alanine amidase
NBV64_RS04770	COG0802	atpase or kinase
NBV64_RS04780	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS04785	COG0280	phosphate acetyltransferase
NBV64_RS04785	COG0281	malic enzyme
NBV64_RS04790	COG0583	DNA-binding transcription factor activity
NBV64_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
NBV64_RS04800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBV64_RS04845	COG1733	regulation of RNA biosynthetic process
NBV64_RS04850	COG2910	NAD(P)H-binding
NBV64_RS04860	COG2223	nitrite transmembrane transporter activity
NBV64_RS04865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBV64_RS04870	COG4974	Belongs to the 'phage' integrase family
NBV64_RS04875	COG0725	ABC transporter, periplasmic molybdate-binding protein
NBV64_RS04880	COG4149	molybdate abc transporter
NBV64_RS04885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NBV64_RS04900	COG1074	ATP-dependent DNA helicase activity
NBV64_RS04935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NBV64_RS04940	COG2226	methyltransferase
NBV64_RS04945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NBV64_RS04950	COG0505	Belongs to the CarA family
NBV64_RS04955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NBV64_RS04975	COG2233	PERMEase
NBV64_RS04980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NBV64_RS04985	COG1534	Rna-binding protein
NBV64_RS04990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NBV64_RS04995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBV64_RS05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBV64_RS05015	COG0248	Ppx GppA phosphatase
NBV64_RS05020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBV64_RS05040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NBV64_RS05045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NBV64_RS05095	COG1231	oxidoreductase activity
NBV64_RS05100	COG2010	Cytochrome c
NBV64_RS05105	COG2323	membrane
NBV64_RS05115	COG1368	sulfuric ester hydrolase activity
NBV64_RS05145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NBV64_RS05150	COG3327	negative regulation of DNA-templated transcription, initiation
NBV64_RS05155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBV64_RS05170	COG0009	L-threonylcarbamoyladenylate synthase
NBV64_RS05175	COG1994	Peptidase M50
NBV64_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBV64_RS05185	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NBV64_RS05200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NBV64_RS05210	COG0156	8-amino-7-oxononanoate synthase activity
NBV64_RS05215	COG2124	cytochrome p450
NBV64_RS05220	COG3135	benzoate transporter
NBV64_RS05225	COG2850	peptidyl-arginine hydroxylation
NBV64_RS05235	COG3391	amine dehydrogenase activity
NBV64_RS05245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBV64_RS05250	COG0577	efflux transmembrane transporter activity
NBV64_RS05250	COG1136	(ABC) transporter
NBV64_RS05255	COG1538	Outer membrane efflux protein
NBV64_RS05260	COG0363	glucosamine-6-phosphate deaminase activity
NBV64_RS05265	COG1132	(ABC) transporter
NBV64_RS05280	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS05285	COG0583	DNA-binding transcription factor activity
NBV64_RS05290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NBV64_RS05300	COG0668	transmembrane transport
NBV64_RS05345	COG0154	amidase activity
NBV64_RS05350	COG2031	fatty acid transporter
NBV64_RS05365	COG0483	inositol monophosphate 1-phosphatase activity
NBV64_RS05370	COG1253	flavin adenine dinucleotide binding
NBV64_RS05375	COG1968	undecaprenyl-diphosphatase activity
NBV64_RS05395	COG0215	cysteine-tRNA ligase activity
NBV64_RS05405	COG0825	malonyl-CoA metabolic process
NBV64_RS05410	COG0037	tRNA processing
NBV64_RS05435	COG0330	HflC and HflK could
NBV64_RS05450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBV64_RS05470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NBV64_RS05475	COG3842	ATPase activity
NBV64_RS05485	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NBV64_RS05515	COG1304	FMN binding
NBV64_RS05520	COG0435	Glutathione S-transferase
NBV64_RS05525	COG0655	NAD(P)H dehydrogenase (quinone) activity
NBV64_RS05540	COG2094	Belongs to the DNA glycosylase MPG family
NBV64_RS05545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NBV64_RS05550	COG2363	Small membrane protein
NBV64_RS05555	COG0598	Magnesium transport protein CorA
NBV64_RS05560	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS05570	COG0747	negative chemotaxis
NBV64_RS05580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBV64_RS05585	COG4172	Belongs to the ABC transporter superfamily
NBV64_RS05595	COG3284	Transcriptional regulator
NBV64_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
NBV64_RS05605	COG1454	alcohol dehydrogenase
NBV64_RS05610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBV64_RS05635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS05665	COG3829	transcription factor binding
NBV64_RS05670	COG0477	Major facilitator Superfamily
NBV64_RS05680	COG0039	L-malate dehydrogenase activity
NBV64_RS05685	COG2188	Transcriptional regulator
NBV64_RS05690	COG2009	succinate dehydrogenase
NBV64_RS05700	COG1053	succinate dehydrogenase
NBV64_RS05705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NBV64_RS05710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NBV64_RS05715	COG0372	Belongs to the citrate synthase family
NBV64_RS05720	COG2186	Transcriptional regulator
NBV64_RS05725	COG1620	l-lactate permease
NBV64_RS05730	COG0038	chloride channel
NBV64_RS05740	COG0281	malic enzyme
NBV64_RS05740	COG0280	phosphate acetyltransferase
NBV64_RS05745	COG0567	Dehydrogenase, E1 component
NBV64_RS05750	COG0508	dehydrogenase complex catalyzes the overall conversion of
NBV64_RS05755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NBV64_RS05760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NBV64_RS05780	COG2183	response to ionizing radiation
NBV64_RS05785	COG1199	ATP-dependent helicase activity
NBV64_RS05805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NBV64_RS05815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS05815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NBV64_RS05830	COG0564	pseudouridine synthase activity
NBV64_RS05840	COG3243	poly(R)-hydroxyalkanoic acid synthase
NBV64_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS05850	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
NBV64_RS05880	COG0653	protein targeting
NBV64_RS05990	COG3728	DNA packaging
NBV64_RS05990	COG5484	DNA packaging
NBV64_RS06000	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NBV64_RS06105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBV64_RS06110	COG1187	pseudouridine synthase activity
NBV64_RS06115	COG0779	Required for maturation of 30S ribosomal subunits
NBV64_RS06120	COG2251	uridine kinase activity
NBV64_RS06120	COG0195	Participates in both transcription termination and antitermination
NBV64_RS06130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBV64_RS06135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBV64_RS06140	COG1217	gtp-binding protein TYPA
NBV64_RS06145	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBV64_RS06155	COG4160	amino acid transport
NBV64_RS06160	COG4215	(ABC) transporter
NBV64_RS06180	COG1283	sodium-dependent phosphate transmembrane transporter activity
NBV64_RS06205	COG0501	Belongs to the peptidase M48B family
NBV64_RS06225	COG1722	exodeoxyribonuclease VII activity
NBV64_RS06230	COG0142	geranyltranstransferase activity
NBV64_RS06235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NBV64_RS06240	COG1469	GTP cyclohydrolase I activity
NBV64_RS06245	COG0360	Binds together with S18 to 16S ribosomal RNA
NBV64_RS06250	COG2965	DNA replication, synthesis of RNA primer
NBV64_RS06255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBV64_RS06265	COG0305	Participates in initiation and elongation during chromosome replication
NBV64_RS06275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NBV64_RS06280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NBV64_RS06285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NBV64_RS06295	COG0436	Aminotransferase
NBV64_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBV64_RS06315	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NBV64_RS06320	COG1562	ergosterol biosynthetic process
NBV64_RS06325	COG1562	ergosterol biosynthetic process
NBV64_RS06330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBV64_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS06360	COG3842	ATPase activity
NBV64_RS06365	COG1176	ABC-type spermidine putrescine transport system, permease component I
NBV64_RS06370	COG1177	transmembrane transport
NBV64_RS06375	COG1393	Belongs to the ArsC family
NBV64_RS06380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBV64_RS06385	COG0704	Plays a role in the regulation of phosphate uptake
NBV64_RS06390	COG2203	Gaf domain
NBV64_RS06390	COG3706	GGDEF domain
NBV64_RS06390	COG4251	negative regulation of phosphorylation
NBV64_RS06390	COG5001	Diguanylate cyclase
NBV64_RS06395	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NBV64_RS06400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NBV64_RS06400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NBV64_RS06405	COG1643	Atp-dependent helicase
NBV64_RS06415	COG0438	transferase activity, transferring glycosyl groups
NBV64_RS06420	COG0726	polysaccharide deacetylase
NBV64_RS06435	COG0438	transferase activity, transferring glycosyl groups
NBV64_RS06460	COG1132	(ABC) transporter
NBV64_RS06510	COG2186	Transcriptional regulator
NBV64_RS06515	COG0277	FAD linked oxidase domain protein
NBV64_RS06520	COG0277	FAD linked oxidase domain protein
NBV64_RS06525	COG0247	lactate metabolic process
NBV64_RS06555	COG2159	amidohydrolase
NBV64_RS06570	COG0583	DNA-binding transcription factor activity
NBV64_RS06575	COG0477	Major facilitator Superfamily
NBV64_RS06615	COG2207	Transcriptional regulator
NBV64_RS06640	COG0628	permease
NBV64_RS06645	COG1283	sodium-dependent phosphate transmembrane transporter activity
NBV64_RS06660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBV64_RS06670	COG0697	spore germination
NBV64_RS06690	COG3094	Invasion gene expression up-regulator, SirB
NBV64_RS06700	COG0640	Transcriptional regulator
NBV64_RS06725	COG0659	secondary active sulfate transmembrane transporter activity
NBV64_RS06730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NBV64_RS06740	COG2314	TM2 domain
NBV64_RS06745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBV64_RS06750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NBV64_RS06755	COG0791	NLP P60 protein
NBV64_RS06775	COG1360	Flagellar Motor Protein
NBV64_RS06785	COG0835	chemotaxis
NBV64_RS06790	COG0840	transmembrane signaling receptor activity
NBV64_RS06795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NBV64_RS06805	COG0745	RESPONSE REGULATOR receiver
NBV64_RS06810	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NBV64_RS06820	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NBV64_RS06845	COG1815	bacterial-type flagellum-dependent cell motility
NBV64_RS06850	COG1558	bacterial-type flagellum-dependent cell motility
NBV64_RS06855	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NBV64_RS06895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NBV64_RS06920	COG2176	DNA-directed DNA polymerase activity
NBV64_RS06930	COG1987	bacterial-type flagellum assembly
NBV64_RS06945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NBV64_RS06955	COG1580	Controls the rotational direction of flagella during chemotaxis
NBV64_RS06970	COG1157	protein secretion by the type III secretion system
NBV64_RS06985	COG1766	The M ring may be actively involved in energy transduction
NBV64_RS06990	COG1677	Flagellar hook-basal body complex protein FliE
NBV64_RS06995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NBV64_RS07020	COG1334	flagellar protein FlaG
NBV64_RS07025	COG1191	sigma factor activity
NBV64_RS07045	COG2733	membrane
NBV64_RS07050	COG0840	transmembrane signaling receptor activity
NBV64_RS07055	COG0840	transmembrane signaling receptor activity
NBV64_RS07070	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS07080	COG2080	2 iron, 2 sulfur cluster binding
NBV64_RS07085	COG2010	Cytochrome c
NBV64_RS07085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBV64_RS07090	COG2610	gluconate transmembrane transporter activity
NBV64_RS07100	COG0582	viral genome integration into host DNA
NBV64_RS07130	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NBV64_RS07140	COG4521	taurine ABC transporter
NBV64_RS07145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NBV64_RS07150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NBV64_RS07155	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS07160	COG0583	DNA-binding transcription factor activity
NBV64_RS07170	COG2824	Alkylphosphonate utilization operon protein PhnA
NBV64_RS07185	COG4771	TonB-dependent receptor
NBV64_RS07190	COG1858	cytochrome C peroxidase
NBV64_RS07210	COG1113	amino acid transport
NBV64_RS07215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBV64_RS07230	COG0583	DNA-binding transcription factor activity
NBV64_RS07235	COG3755	Protein conserved in bacteria
NBV64_RS07240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NBV64_RS07280	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBV64_RS07305	COG1278	Cold shock
NBV64_RS07310	COG0642	Histidine kinase
NBV64_RS07320	COG3278	Belongs to the heme-copper respiratory oxidase family
NBV64_RS07335	COG3258	Cytochrome c
NBV64_RS07340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NBV64_RS07365	COG0025	NhaP-type Na H and K H
NBV64_RS07380	COG1289	transmembrane transporter activity
NBV64_RS07385	COG2252	PERMEase
NBV64_RS07405	COG1999	signal sequence binding
NBV64_RS07420	COG0069	glutamate synthase activity
NBV64_RS07430	COG1846	Transcriptional regulator
NBV64_RS07435	COG1058	Belongs to the CinA family
NBV64_RS07435	COG1546	Belongs to the CinA family
NBV64_RS07440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NBV64_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS07490	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NBV64_RS07490	COG3264	Mechanosensitive ion channel
NBV64_RS07495	COG1196	nuclear chromosome segregation
NBV64_RS07495	COG3264	Mechanosensitive ion channel
NBV64_RS07500	COG0477	Major facilitator Superfamily
NBV64_RS07515	COG1396	sequence-specific DNA binding
NBV64_RS07520	COG3437	response regulator, receiver
NBV64_RS07525	COG0784	Response regulator, receiver
NBV64_RS07525	COG2198	Histidine kinase
NBV64_RS07525	COG2205	protein histidine kinase activity
NBV64_RS07530	COG2239	Acts as a magnesium transporter
NBV64_RS07540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NBV64_RS07545	COG1490	D-aminoacyl-tRNA deacylase activity
NBV64_RS07560	COG0456	acetyltransferase
NBV64_RS07570	COG0501	Belongs to the peptidase M48B family
NBV64_RS07580	COG2814	Major facilitator Superfamily
NBV64_RS07590	COG4115	mRNA cleavage
NBV64_RS07595	COG2161	toxin-antitoxin pair type II binding
NBV64_RS07725	COG3772	lysozyme
NBV64_RS07775	COG2199	diguanylate cyclase activity
NBV64_RS07790	COG1522	sequence-specific DNA binding
NBV64_RS07795	COG0626	cystathionine gamma-synthase activity
NBV64_RS07805	COG0494	nUDIX hydrolase
NBV64_RS07810	COG2832	Protein of unknown function (DUF454)
NBV64_RS07820	COG0137	argininosuccinate synthase activity
NBV64_RS07825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NBV64_RS07830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NBV64_RS07850	COG1609	Transcriptional regulator
NBV64_RS07855	COG0519	Catalyzes the synthesis of GMP from XMP
NBV64_RS07855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NBV64_RS07865	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NBV64_RS07875	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NBV64_RS07880	COG2205	protein histidine kinase activity
NBV64_RS07885	COG0745	RESPONSE REGULATOR receiver
NBV64_RS07890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NBV64_RS07900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBV64_RS07905	COG0268	Binds directly to 16S ribosomal RNA
NBV64_RS07910	COG0728	peptidoglycan biosynthetic process
NBV64_RS07920	COG0563	adenylate kinase activity
NBV64_RS07925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NBV64_RS07930	COG2835	tetraacyldisaccharide 4'-kinase activity
NBV64_RS07935	COG1663	tetraacyldisaccharide 4'-kinase activity
NBV64_RS07940	COG0848	biopolymer transport protein
NBV64_RS07945	COG0811	peptide transport
NBV64_RS07950	COG1570	exodeoxyribonuclease VII activity
NBV64_RS07955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NBV64_RS07970	COG0183	Belongs to the thiolase family
NBV64_RS07980	COG1278	Cold shock
NBV64_RS07985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NBV64_RS07990	COG0542	response to heat
NBV64_RS07995	COG2995	paraquat-inducible protein a
NBV64_RS08000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NBV64_RS08000	COG3008	intermembrane lipid transfer
NBV64_RS08020	COG0559	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS08055	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NBV64_RS08060	COG0756	dUTP diphosphatase activity
NBV64_RS08070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBV64_RS08075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBV64_RS08080	COG0196	riboflavin kinase activity
NBV64_RS08085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBV64_RS08090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBV64_RS08090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBV64_RS08100	COG0210	DNA helicase
NBV64_RS08150	COG0488	(ABC) transporter
NBV64_RS08155	COG2890	protein-(glutamine-N5) methyltransferase activity
NBV64_RS08160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NBV64_RS08165	COG2171	N-acyltransferase activity
NBV64_RS08175	COG2207	Transcriptional regulator
NBV64_RS08185	COG0471	metal ion transport
NBV64_RS08185	COG3273	potassium ion transport
NBV64_RS08225	COG0789	Transcriptional regulator
NBV64_RS08240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NBV64_RS08245	COG0544	peptidyl-prolyl cis-trans isomerase activity
NBV64_RS08250	COG0740	serine-type endopeptidase activity
NBV64_RS08260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NBV64_RS08280	COG0556	nucleotide-excision repair
NBV64_RS08285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBV64_RS08295	COG1104	cysteine desulfurase activity
NBV64_RS08305	COG0316	Belongs to the HesB IscA family
NBV64_RS08315	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS08320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NBV64_RS08325	COG4221	oxidoreductase activity
NBV64_RS08335	COG0840	transmembrane signaling receptor activity
NBV64_RS08340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBV64_RS08345	COG0697	spore germination
NBV64_RS08350	COG0385	Bile acid
NBV64_RS08360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NBV64_RS08375	COG1136	(ABC) transporter
NBV64_RS08380	COG0084	hydrolase, TatD family'
NBV64_RS08395	COG0613	PHP domain protein
NBV64_RS08405	COG0047	phosphoribosylformylglycinamidine synthase activity
NBV64_RS08405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBV64_RS08430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NBV64_RS08430	COG0519	Catalyzes the synthesis of GMP from XMP
NBV64_RS08445	COG0583	DNA-binding transcription factor activity
NBV64_RS08460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NBV64_RS08470	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS08485	COG0523	cobalamin synthesis protein
NBV64_RS08490	COG1469	GTP cyclohydrolase I activity
NBV64_RS08495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NBV64_RS08505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NBV64_RS08510	COG0735	belongs to the Fur family
NBV64_RS08515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NBV64_RS08535	COG0745	RESPONSE REGULATOR receiver
NBV64_RS08550	COG1942	4-Oxalocrotonate Tautomerase
NBV64_RS08565	COG2070	2-Nitropropane dioxygenase
NBV64_RS08605	COG0625	glutathione transferase activity
NBV64_RS08610	COG0740	serine-type endopeptidase activity
NBV64_RS08635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NBV64_RS08660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NBV64_RS08670	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS08695	COG0640	Transcriptional regulator
NBV64_RS08720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NBV64_RS08745	COG3485	protocatechuate 3,4-dioxygenase
NBV64_RS08755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NBV64_RS08760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NBV64_RS08770	COG3135	benzoate transporter
NBV64_RS08775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBV64_RS08780	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NBV64_RS08795	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NBV64_RS08805	COG2197	response regulator
NBV64_RS08810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NBV64_RS08835	COG1846	Transcriptional regulator
NBV64_RS08840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBV64_RS08845	COG2271	Major facilitator Superfamily
NBV64_RS08855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NBV64_RS08865	COG0697	spore germination
NBV64_RS08890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NBV64_RS08895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NBV64_RS08900	COG0667	Aldo Keto reductase
NBV64_RS08920	COG0582	viral genome integration into host DNA
NBV64_RS08980	COG1278	Cold shock
NBV64_RS09075	COG3728	DNA packaging
NBV64_RS09220	COG2135	peptidase activity
NBV64_RS09230	COG1272	protein, Hemolysin III
NBV64_RS09235	COG3422	double-strand break repair
NBV64_RS09260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS09265	COG0765	amino acid transport
NBV64_RS09270	COG0765	amino acid transport
NBV64_RS09275	COG1126	abc transporter atp-binding protein
NBV64_RS09325	COG2871	sodium ion transport
NBV64_RS09355	COG2814	Major facilitator Superfamily
NBV64_RS09360	COG1280	lysine exporter protein (LysE YggA)
NBV64_RS09365	COG1609	Transcriptional regulator
NBV64_RS09375	COG0402	S-adenosylhomocysteine deaminase activity
NBV64_RS09400	COG0330	HflC and HflK could
NBV64_RS09405	COG1585	Membrane protein implicated in regulation of membrane protease activity
NBV64_RS09410	COG2226	methyltransferase
NBV64_RS09420	COG3042	response to heat
NBV64_RS09430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBV64_RS09450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBV64_RS09455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBV64_RS09470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBV64_RS09475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBV64_RS09515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NBV64_RS09520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBV64_RS09525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBV64_RS09530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBV64_RS09530	COG0072	phenylalanine-tRNA ligase activity
NBV64_RS09545	COG2833	Protein of unknown function (DUF455)
NBV64_RS09560	COG5265	(ABC) transporter
NBV64_RS09565	COG1959	2 iron, 2 sulfur cluster binding
NBV64_RS09570	COG0719	Fe-S assembly protein
NBV64_RS09575	COG0396	ATPase activity
NBV64_RS09580	COG0719	Fe-S assembly protein
NBV64_RS09590	COG0822	iron-sulfur transferase activity
NBV64_RS09595	COG2151	metal-sulfur cluster biosynthetic enzyme
NBV64_RS09630	COG1215	transferase activity, transferring glycosyl groups
NBV64_RS09635	COG0726	polysaccharide deacetylase
NBV64_RS09635	COG1649	PFAM Uncharacterised BCR, COG1649
NBV64_RS09640	COG0457	Tetratricopeptide repeat
NBV64_RS09670	COG0747	negative chemotaxis
NBV64_RS09675	COG0601	transmembrane transport
NBV64_RS09680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBV64_RS09685	COG4172	Belongs to the ABC transporter superfamily
NBV64_RS09695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NBV64_RS09750	COG0604	alcohol dehydrogenase
NBV64_RS09755	COG2207	Transcriptional regulator
NBV64_RS09760	COG3048	D-serine ammonia-lyase activity
NBV64_RS09770	COG3949	Membrane
NBV64_RS09780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NBV64_RS09795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NBV64_RS09800	COG0569	domain protein
NBV64_RS09805	COG1902	pentaerythritol trinitrate reductase activity
NBV64_RS09815	COG1610	YqeY-like protein
NBV64_RS09820	COG0587	DNA-directed DNA polymerase activity
NBV64_RS09860	COG0583	DNA-binding transcription factor activity
NBV64_RS09865	COG1686	Belongs to the peptidase S11 family
NBV64_RS09880	COG1360	Flagellar Motor Protein
NBV64_RS09890	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NBV64_RS09900	COG4221	oxidoreductase activity
NBV64_RS09910	COG0307	riboflavin synthase, alpha
NBV64_RS09955	COG2233	PERMEase
NBV64_RS09960	COG0071	Belongs to the small heat shock protein (HSP20) family
NBV64_RS09965	COG1473	amidohydrolase
NBV64_RS09975	COG2814	Major facilitator Superfamily
NBV64_RS10005	COG2816	NAD+ diphosphatase activity
NBV64_RS10010	COG1561	YicC-like family, N-terminal region
NBV64_RS10025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NBV64_RS10030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NBV64_RS10035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NBV64_RS10040	COG0174	glutamine synthetase
NBV64_RS10045	COG2153	protein acetylation
NBV64_RS10065	COG3842	ATPase activity
NBV64_RS10070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NBV64_RS10075	COG1840	ABC-type Fe3 transport system, periplasmic component
NBV64_RS10090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBV64_RS10100	COG0783	Belongs to the Dps family
NBV64_RS10110	COG3842	ATPase activity
NBV64_RS10115	COG0395	ABC-type sugar transport system, permease component
NBV64_RS10120	COG1175	transmembrane transport
NBV64_RS10125	COG1653	transport
NBV64_RS10140	COG0559	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS10160	COG0625	glutathione transferase activity
NBV64_RS10170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBV64_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS10185	COG0114	fumarate hydratase activity
NBV64_RS10190	COG2133	pyrroloquinoline quinone binding
NBV64_RS10195	COG0589	response to stress
NBV64_RS10205	COG2807	transmembrane transport
NBV64_RS10215	COG0583	DNA-binding transcription factor activity
NBV64_RS10250	COG0583	DNA-binding transcription factor activity
NBV64_RS10255	COG4974	Belongs to the 'phage' integrase family
NBV64_RS10265	COG2132	Multicopper oxidase
NBV64_RS10270	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NBV64_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS10315	COG3038	cytochrome b561
NBV64_RS10325	COG2353	YceI-like domain
NBV64_RS10330	COG1393	Belongs to the ArsC family
NBV64_RS10335	COG0625	glutathione transferase activity
NBV64_RS10360	COG0084	hydrolase, TatD family'
NBV64_RS10365	COG0470	DNA polymerase III
NBV64_RS10375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NBV64_RS10395	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS10400	COG2914	Belongs to the UPF0125 (RnfH) family
NBV64_RS10405	COG2867	negative regulation of translational initiation
NBV64_RS10410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NBV64_RS10415	COG1252	NADH dehydrogenase
NBV64_RS10440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBV64_RS10445	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBV64_RS10450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBV64_RS10460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NBV64_RS10465	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBV64_RS10475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBV64_RS10485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NBV64_RS10490	COG0575	Belongs to the CDS family
NBV64_RS10495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBV64_RS10500	COG0233	cytoplasmic translational termination
NBV64_RS10505	COG0528	UMP kinase activity
NBV64_RS10510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBV64_RS10515	COG0052	Belongs to the universal ribosomal protein uS2 family
NBV64_RS10520	COG0024	Methionine aminopeptidase
NBV64_RS10525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NBV64_RS10550	COG1286	toxin biosynthetic process
NBV64_RS10560	COG0285	dihydrofolate synthase activity
NBV64_RS10565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NBV64_RS10570	COG0508	dehydrogenase complex catalyzes the overall conversion of
NBV64_RS10575	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NBV64_RS10585	COG4566	intracellular signal transduction
NBV64_RS10590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBV64_RS10605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBV64_RS10610	COG0640	Transcriptional regulator
NBV64_RS10630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NBV64_RS10640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBV64_RS10645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBV64_RS10650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NBV64_RS10670	COG0183	Belongs to the thiolase family
NBV64_RS10675	COG0183	Belongs to the thiolase family
NBV64_RS10685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NBV64_RS10720	COG0194	GDP metabolic process
NBV64_RS10725	COG1758	RNA polymerase activity
NBV64_RS10730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBV64_RS10740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NBV64_RS10745	COG0739	heme binding
NBV64_RS10750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBV64_RS10755	COG0584	glycerophosphoryl diester phosphodiesterase
NBV64_RS10760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NBV64_RS10765	COG1187	pseudouridine synthase activity
NBV64_RS10770	COG3161	chorismate lyase activity
NBV64_RS10775	COG2814	Major facilitator Superfamily
NBV64_RS10780	COG0656	L-ascorbic acid biosynthetic process
NBV64_RS10790	COG0668	transmembrane transport
NBV64_RS10795	COG0165	Argininosuccinate lyase
NBV64_RS10810	COG1846	Transcriptional regulator
NBV64_RS10810	COG1940	carbohydrate kinase activity
NBV64_RS10820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBV64_RS10830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBV64_RS10840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NBV64_RS10845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NBV64_RS10850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NBV64_RS10855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBV64_RS10860	COG2252	PERMEase
NBV64_RS10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NBV64_RS10885	COG0488	(ABC) transporter
NBV64_RS10890	COG1619	proteins homologs of microcin C7 resistance protein MccF
NBV64_RS10895	COG0590	tRNA wobble adenosine to inosine editing
NBV64_RS10900	COG1131	(ABC) transporter
NBV64_RS10905	COG0842	Transport permease protein
NBV64_RS10915	COG1666	GTP binding
NBV64_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
NBV64_RS10925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBV64_RS10930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NBV64_RS10930	COG0519	Catalyzes the synthesis of GMP from XMP
NBV64_RS10935	COG2207	Transcriptional regulator
NBV64_RS10950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NBV64_RS10955	COG0135	phosphoribosylanthranilate isomerase activity
NBV64_RS10960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS10970	COG0101	tRNA pseudouridine synthase activity
NBV64_RS10980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBV64_RS10985	COG0473	3-isopropylmalate dehydrogenase activity
NBV64_RS11005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NBV64_RS11015	COG4566	intracellular signal transduction
NBV64_RS11030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NBV64_RS11035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NBV64_RS11045	COG1295	ribonuclease BN
NBV64_RS11055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBV64_RS11065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NBV64_RS11095	COG4964	Belongs to the GSP D family
NBV64_RS11140	COG2959	enzyme of heme biosynthesis
NBV64_RS11150	COG0181	hydroxymethylbilane synthase activity
NBV64_RS11155	COG0861	Integral membrane protein TerC family
NBV64_RS11160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NBV64_RS11165	COG0045	succinate-CoA ligase (ADP-forming) activity
NBV64_RS11175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NBV64_RS11180	COG0583	DNA-binding transcription factor activity
NBV64_RS11185	COG2137	regulation of response to DNA damage stimulus
NBV64_RS11190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBV64_RS11200	COG0642	Histidine kinase
NBV64_RS11205	COG0477	Major facilitator Superfamily
NBV64_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
NBV64_RS11225	COG1024	Enoyl-CoA hydratase
NBV64_RS11230	COG3162	membrane
NBV64_RS11245	COG0540	Belongs to the ATCase OTCase family
NBV64_RS11260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NBV64_RS11275	COG2070	2-Nitropropane dioxygenase
NBV64_RS11285	COG2111	Na H antiporter
NBV64_RS11285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NBV64_RS11290	COG1006	Multisubunit Na H antiporter MnhC subunit
NBV64_RS11295	COG0651	ATP synthesis coupled electron transport
NBV64_RS11305	COG2212	antiporter activity
NBV64_RS11320	COG3158	transport of potassium into the cell
NBV64_RS11325	COG0642	Histidine kinase
NBV64_RS11350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NBV64_RS11355	COG4208	sulfate ABC transporter
NBV64_RS11360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NBV64_RS11365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NBV64_RS11385	COG1278	Cold shock
NBV64_RS11400	COG1648	precorrin-2 dehydrogenase activity
NBV64_RS11400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBV64_RS11410	COG3391	amine dehydrogenase activity
NBV64_RS11415	COG1522	sequence-specific DNA binding
NBV64_RS11430	COG0535	radical SAM domain protein
NBV64_RS11435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBV64_RS11435	COG1648	precorrin-2 dehydrogenase activity
NBV64_RS11445	COG2010	Cytochrome c
NBV64_RS11450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS11455	COG0626	cystathionine gamma-synthase activity
NBV64_RS11460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBV64_RS11465	COG0557	exoribonuclease II activity
NBV64_RS11505	COG2375	cellular response to nickel ion
NBV64_RS11535	COG0583	DNA-binding transcription factor activity
NBV64_RS11540	COG3842	ATPase activity
NBV64_RS11550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBV64_RS11555	COG1840	ABC-type Fe3 transport system, periplasmic component
NBV64_RS11575	COG0412	Dienelactone hydrolase
NBV64_RS11580	COG3530	Putative quorum-sensing-regulated virulence factor
NBV64_RS11585	COG0625	glutathione transferase activity
NBV64_RS11595	COG1741	Belongs to the pirin family
NBV64_RS11605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBV64_RS11610	COG2814	Major facilitator Superfamily
NBV64_RS11615	COG2807	transmembrane transport
NBV64_RS11620	COG2207	Transcriptional regulator
NBV64_RS11625	COG3135	benzoate transporter
NBV64_RS11650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBV64_RS11660	COG0402	S-adenosylhomocysteine deaminase activity
NBV64_RS11670	COG0745	RESPONSE REGULATOR receiver
NBV64_RS11675	COG2205	protein histidine kinase activity
NBV64_RS11690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NBV64_RS11695	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NBV64_RS11700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBV64_RS11710	COG0330	HflC and HflK could
NBV64_RS11715	COG0330	HflC and HflK could
NBV64_RS11720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBV64_RS11725	COG1923	regulation of RNA biosynthetic process
NBV64_RS11735	COG1160	GTP binding
NBV64_RS11740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBV64_RS11745	COG2976	Protein conserved in bacteria
NBV64_RS11765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NBV64_RS11770	COG0105	UTP biosynthetic process
NBV64_RS11780	COG0583	DNA-binding transcription factor activity
NBV64_RS11785	COG0697	spore germination
NBV64_RS11790	COG0336	Belongs to the RNA methyltransferase TrmD family
NBV64_RS11800	COG0228	four-way junction DNA binding
NBV64_RS11805	COG0425	Belongs to the sulfur carrier protein TusA family
NBV64_RS11810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBV64_RS11825	COG2351	hydroxyisourate hydrolase activity
NBV64_RS11860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBV64_RS11885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NBV64_RS11890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NBV64_RS11905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NBV64_RS11910	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NBV64_RS11915	COG0542	response to heat
NBV64_RS11920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NBV64_RS11935	COG0348	domain, Protein
NBV64_RS11955	COG3278	Belongs to the heme-copper respiratory oxidase family
NBV64_RS11965	COG2217	Heavy metal translocating P-type atpase
NBV64_RS11970	COG2224	Isocitrate lyase
NBV64_RS11975	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NBV64_RS11975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NBV64_RS11995	COG1472	Belongs to the glycosyl hydrolase 3 family
NBV64_RS12000	COG0736	holo-[acyl-carrier-protein] synthase activity
NBV64_RS12010	COG2050	protein possibly involved in aromatic compounds catabolism
NBV64_RS12015	COG1024	Enoyl-CoA hydratase
NBV64_RS12020	COG1012	belongs to the aldehyde dehydrogenase family
NBV64_RS12025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBV64_RS12030	COG2151	metal-sulfur cluster biosynthetic enzyme
NBV64_RS12035	COG3396	Phenylacetate-CoA oxygenase
NBV64_RS12040	COG3460	Phenylacetate-CoA oxygenase
NBV64_RS12045	COG3396	Phenylacetate-CoA oxygenase
NBV64_RS12050	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NBV64_RS12055	COG0501	Belongs to the peptidase M48B family
NBV64_RS12060	COG1162	GTPase activity
NBV64_RS12070	COG0335	large ribosomal subunit rRNA binding
NBV64_RS12090	COG0450	alkyl hydroperoxide reductase
NBV64_RS12095	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS12110	COG0123	including yeast histone deacetylase and acetoin utilization protein
NBV64_RS12115	COG2951	lytic endotransglycosylase activity
NBV64_RS12130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NBV64_RS12135	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NBV64_RS12140	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NBV64_RS12160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NBV64_RS12165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NBV64_RS12170	COG0287	Prephenate dehydrogenase
NBV64_RS12180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NBV64_RS12195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NBV64_RS12205	COG0583	DNA-binding transcription factor activity
NBV64_RS12215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NBV64_RS12235	COG0753	catalase activity
NBV64_RS12240	COG1408	metallophosphoesterase
NBV64_RS12245	COG4335	DNA alkylation repair
NBV64_RS12255	COG0436	Aminotransferase
NBV64_RS12265	COG0251	oxidation-reduction process
NBV64_RS12270	COG1309	transcriptional regulator
NBV64_RS12280	COG0488	(ABC) transporter
NBV64_RS12315	COG0625	glutathione transferase activity
NBV64_RS12325	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NBV64_RS12330	COG1280	lysine exporter protein (LysE YggA)
NBV64_RS12350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NBV64_RS12360	COG2205	protein histidine kinase activity
NBV64_RS12360	COG0784	Response regulator, receiver
NBV64_RS12360	COG2198	Histidine kinase
NBV64_RS12365	COG2046	Belongs to the sulfate adenylyltransferase family
NBV64_RS12370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NBV64_RS12385	COG0840	transmembrane signaling receptor activity
NBV64_RS12390	COG2119	membrane
NBV64_RS12405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NBV64_RS12410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NBV64_RS12425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NBV64_RS12430	COG2321	neutral zinc metallopeptidase
NBV64_RS12440	COG2271	Major facilitator Superfamily
NBV64_RS12445	COG2175	clavaminate synthase activity
NBV64_RS12450	COG1846	Transcriptional regulator
NBV64_RS12455	COG0347	Belongs to the P(II) protein family
NBV64_RS12460	COG0004	ammonium transporteR
NBV64_RS12465	COG3909	cytochrome
NBV64_RS12475	COG0625	glutathione transferase activity
NBV64_RS12485	COG0657	acetylesterase activity
NBV64_RS12490	COG0730	response to heat
NBV64_RS12495	COG0482	sulfurtransferase activity
NBV64_RS12500	COG0277	FAD linked oxidase domain protein
NBV64_RS12505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NBV64_RS12510	COG2879	small protein
NBV64_RS12515	COG1966	Carbon starvation protein
NBV64_RS12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS12525	COG0765	amino acid transport
NBV64_RS12530	COG0765	amino acid transport
NBV64_RS12535	COG1126	abc transporter atp-binding protein
NBV64_RS12545	COG5285	phytanoyl-CoA dioxygenase
NBV64_RS12550	COG0662	Cupin 2, conserved barrel domain protein
NBV64_RS12560	COG0456	acetyltransferase
NBV64_RS12565	COG1846	Transcriptional regulator
NBV64_RS12575	COG0312	modulator of DNA gyrase
NBV64_RS12590	COG0308	aminopeptidase N
NBV64_RS12595	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NBV64_RS12610	COG0473	3-isopropylmalate dehydrogenase activity
NBV64_RS12615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NBV64_RS12620	COG0433	COG0433 Predicted ATPase
NBV64_RS12625	COG0217	transcriptional regulatory protein
NBV64_RS12630	COG0151	Belongs to the GarS family
NBV64_RS12640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBV64_RS12645	COG0799	negative regulation of ribosome biogenesis
NBV64_RS12650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBV64_RS12655	COG0424	maF-like protein
NBV64_RS12675	COG0023	Translation Initiation Factor
NBV64_RS12685	COG2084	Dehydrogenase
NBV64_RS12690	COG0625	glutathione transferase activity
NBV64_RS12695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NBV64_RS12700	COG1047	Peptidyl-prolyl cis-trans
NBV64_RS12705	COG2003	Belongs to the UPF0758 family
NBV64_RS12710	COG1737	Transcriptional regulator
NBV64_RS12715	COG0477	Major facilitator Superfamily
NBV64_RS12745	COG0534	Mate efflux family protein
NBV64_RS12750	COG4175	Glycine betaine
NBV64_RS12755	COG4176	ABC-type proline glycine betaine transport system permease component
NBV64_RS12765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NBV64_RS12770	COG2814	Major facilitator Superfamily
NBV64_RS12775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NBV64_RS12780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NBV64_RS12785	COG0495	leucyl-tRNA aminoacylation
NBV64_RS12795	COG1466	dna polymerase III delta subunit
NBV64_RS12800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBV64_RS12805	COG1981	membrane
NBV64_RS12820	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBV64_RS12830	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NBV64_RS12835	COG0148	phosphopyruvate hydratase activity
NBV64_RS12845	COG2814	Major facilitator Superfamily
NBV64_RS12860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NBV64_RS12870	COG0504	CTP synthase activity
NBV64_RS12905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NBV64_RS12915	COG0791	NLP P60 protein
NBV64_RS12925	COG0583	DNA-binding transcription factor activity
NBV64_RS12935	COG0583	DNA-binding transcription factor activity
NBV64_RS12945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NBV64_RS12960	COG1045	serine acetyltransferase
NBV64_RS12975	COG1381	Involved in DNA repair and RecF pathway recombination
NBV64_RS12980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBV64_RS12985	COG0571	ribonuclease III activity
NBV64_RS13000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NBV64_RS13025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NBV64_RS13030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBV64_RS13035	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS13040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NBV64_RS13045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBV64_RS13055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NBV64_RS13060	COG1399	metal-binding, possibly nucleic acid-binding protein
NBV64_RS13065	COG0424	maF-like protein
NBV64_RS13075	COG3023	N-Acetylmuramoyl-L-alanine amidase
NBV64_RS13080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NBV64_RS13085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NBV64_RS13090	COG0546	phosphoglycolate phosphatase activity
NBV64_RS13095	COG0564	pseudouridine synthase activity
NBV64_RS13100	COG1530	ribonuclease E activity
NBV64_RS13105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBV64_RS13110	COG0159	tryptophan synthase activity
NBV64_RS13115	COG0133	tryptophan synthase activity
NBV64_RS13120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBV64_RS13130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBV64_RS13135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NBV64_RS13145	COG2878	Part of a membrane complex involved in electron transport
NBV64_RS13150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NBV64_RS13155	COG1129	ABC transporter
NBV64_RS13160	COG3047	cAMP biosynthetic process
NBV64_RS13185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBV64_RS13190	COG2917	probably involved in intracellular septation
NBV64_RS13200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBV64_RS13205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBV64_RS13215	COG1196	nuclear chromosome segregation
NBV64_RS13225	COG1573	uracil-dna glycosylase
NBV64_RS13230	COG1214	PFAM Peptidase M22, glycoprotease
NBV64_RS13245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NBV64_RS13250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NBV64_RS13255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBV64_RS13260	COG0560	Phosphoserine phosphatase
NBV64_RS13265	COG2070	2-Nitropropane dioxygenase
NBV64_RS13275	COG1007	ATP synthesis coupled electron transport
NBV64_RS13290	COG0713	ATP synthesis coupled electron transport
NBV64_RS13300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBV64_RS13305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NBV64_RS13310	COG1034	ATP synthesis coupled electron transport
NBV64_RS13325	COG0649	NAD binding
NBV64_RS13330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBV64_RS13335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBV64_RS13340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBV64_RS13345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBV64_RS13360	COG0149	triose-phosphate isomerase activity
NBV64_RS13365	COG0604	alcohol dehydrogenase
NBV64_RS13380	COG1185	polyribonucleotide nucleotidyltransferase activity
NBV64_RS13385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBV64_RS13390	COG1183	phosphatidylcholine synthase activity
NBV64_RS13395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NBV64_RS13400	COG0440	acetolactate synthase activity
NBV64_RS13405	COG0028	Belongs to the TPP enzyme family
NBV64_RS13410	COG1289	transmembrane transporter activity
NBV64_RS13415	COG3022	response to hydroperoxide
NBV64_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS13440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBV64_RS13445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NBV64_RS13450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NBV64_RS13455	COG1674	ftsk spoiiie
NBV64_RS13460	COG0492	ferredoxin-NADP+ reductase activity
NBV64_RS13480	COG0477	Major facilitator Superfamily
NBV64_RS13500	COG2272	Belongs to the type-B carboxylesterase lipase family
NBV64_RS13505	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS13530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBV64_RS13550	COG2204	response regulator
NBV64_RS13590	COG4964	Belongs to the GSP D family
NBV64_RS13650	COG0612	Peptidase, M16
NBV64_RS13655	COG0484	heat shock protein binding
NBV64_RS13660	COG0443	Heat shock 70 kDa protein
NBV64_RS13665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBV64_RS13670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NBV64_RS13675	COG1420	regulation of RNA biosynthetic process
NBV64_RS13685	COG0497	DNA recombination
NBV64_RS13690	COG0735	belongs to the Fur family
NBV64_RS13695	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBV64_RS13700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NBV64_RS13715	COG2267	carboxylic ester hydrolase activity
NBV64_RS13725	COG0477	Major facilitator Superfamily
NBV64_RS13735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NBV64_RS13765	COG1538	Outer membrane efflux protein
NBV64_RS13825	COG2814	Major facilitator Superfamily
NBV64_RS13840	COG2819	hydrolase of the alpha beta superfamily
NBV64_RS13845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NBV64_RS13860	COG1454	alcohol dehydrogenase
NBV64_RS13895	COG1414	Transcriptional regulator
NBV64_RS13900	COG0513	Belongs to the DEAD box helicase family
NBV64_RS13910	COG0583	DNA-binding transcription factor activity
NBV64_RS13915	COG4638	Rieske (2fe-2S)
NBV64_RS13920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NBV64_RS13935	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBV64_RS13950	COG3971	2-oxopent-4-enoate hydratase activity
NBV64_RS13955	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NBV64_RS13965	COG2814	Major facilitator Superfamily
NBV64_RS13985	COG3121	Chaperone
NBV64_RS13995	COG2205	protein histidine kinase activity
NBV64_RS13995	COG0784	Response regulator, receiver
NBV64_RS14000	COG0784	Response regulator, receiver
NBV64_RS14000	COG2205	protein histidine kinase activity
NBV64_RS14005	COG2197	response regulator
NBV64_RS14025	COG0154	amidase activity
NBV64_RS14030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS14035	COG2814	Major facilitator Superfamily
NBV64_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS14080	COG0842	Transport permease protein
NBV64_RS14085	COG1129	ABC transporter
NBV64_RS14085	COG0842	Transport permease protein
NBV64_RS14090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBV64_RS14095	COG1538	Outer membrane efflux protein
NBV64_RS14100	COG3243	poly(R)-hydroxyalkanoic acid synthase
NBV64_RS14110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NBV64_RS14115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NBV64_RS14125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBV64_RS14140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBV64_RS14155	COG0505	Belongs to the CarA family
NBV64_RS14160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NBV64_RS14170	COG0789	Transcriptional regulator
NBV64_RS14180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBV64_RS14225	COG3278	Belongs to the heme-copper respiratory oxidase family
NBV64_RS14230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS14250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NBV64_RS14300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NBV64_RS14365	COG0516	GMP reductase activity
NBV64_RS14365	COG0517	IMP dehydrogenase activity
NBV64_RS14380	COG1027	Aspartate ammonia-lyase
NBV64_RS14385	COG1846	Transcriptional regulator
NBV64_RS14405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NBV64_RS14410	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NBV64_RS14425	COG1414	Transcriptional regulator
NBV64_RS14445	COG0513	Belongs to the DEAD box helicase family
NBV64_RS14465	COG0429	hydrolase of the alpha beta-hydrolase fold
NBV64_RS14490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBV64_RS14500	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NBV64_RS14510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NBV64_RS14515	COG0632	four-way junction helicase activity
NBV64_RS14525	COG2255	four-way junction helicase activity
NBV64_RS14535	COG0418	dihydroorotase activity
NBV64_RS14545	COG0415	Belongs to the DNA photolyase family
NBV64_RS14610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBV64_RS14615	COG4654	Cytochrome c, class I
NBV64_RS14655	COG1177	transmembrane transport
NBV64_RS14660	COG3842	ATPase activity
NBV64_RS14665	COG1840	ABC-type Fe3 transport system, periplasmic component
NBV64_RS14670	COG2084	Dehydrogenase
NBV64_RS14685	COG0494	nUDIX hydrolase
NBV64_RS14690	COG0442	prolyl-tRNA aminoacylation
NBV64_RS14695	COG0824	Thioesterase
NBV64_RS14700	COG0811	peptide transport
NBV64_RS14715	COG0823	Involved in the tonB-independent uptake of proteins
NBV64_RS14730	COG0596	Alpha beta hydrolase
NBV64_RS14755	COG1079	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS14760	COG4603	Belongs to the binding-protein-dependent transport system permease family
NBV64_RS14765	COG3845	ABC transporter
NBV64_RS14785	COG0427	acetyl-CoA hydrolase
NBV64_RS14790	COG0583	DNA-binding transcription factor activity
NBV64_RS14795	COG3634	alkyl hydroperoxide reductase activity
NBV64_RS14810	COG0697	spore germination
NBV64_RS14815	COG0175	sulfate reduction
NBV64_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
NBV64_RS14840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBV64_RS14845	COG5383	Protein conserved in bacteria
NBV64_RS14855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBV64_RS14870	COG0583	DNA-binding transcription factor activity
NBV64_RS14875	COG1741	Belongs to the pirin family
NBV64_RS14885	COG3706	GGDEF domain
NBV64_RS14890	COG0154	amidase activity
NBV64_RS14905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBV64_RS14915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NBV64_RS14920	COG0284	orotidine-5'-phosphate decarboxylase activity
NBV64_RS14935	COG1414	Transcriptional regulator
NBV64_RS14945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NBV64_RS14950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NBV64_RS14955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBV64_RS14960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NBV64_RS14985	COG0742	ribosomal rna small subunit methyltransferase
NBV64_RS14990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBV64_RS14995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NBV64_RS15025	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NBV64_RS15050	COG1335	isochorismatase
NBV64_RS15055	COG2309	aminopeptidase activity
NBV64_RS15060	COG0596	Alpha beta hydrolase
NBV64_RS15065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBV64_RS15065	COG2010	Cytochrome c
NBV64_RS15070	COG2080	2 iron, 2 sulfur cluster binding
NBV64_RS15075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBV64_RS15075	COG2010	Cytochrome c
NBV64_RS15085	COG0410	ABC transporter
NBV64_RS15090	COG0411	ABC transporter
NBV64_RS15115	COG3706	GGDEF domain
NBV64_RS15130	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS15145	COG1234	tRNA 3'-trailer cleavage
NBV64_RS15150	COG2188	Transcriptional regulator
NBV64_RS15160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBV64_RS15170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBV64_RS15170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NBV64_RS15175	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NBV64_RS15175	COG3608	succinylglutamate desuccinylase aspartoacylase
NBV64_RS15180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NBV64_RS15190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NBV64_RS15195	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NBV64_RS15220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS15245	COG1335	isochorismatase
NBV64_RS15250	COG2309	aminopeptidase activity
NBV64_RS15255	COG0596	Alpha beta hydrolase
NBV64_RS15270	COG1120	ATPase activity
NBV64_RS15275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBV64_RS15285	COG4206	TonB-dependent receptor
NBV64_RS15290	COG2031	fatty acid transporter
NBV64_RS15305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBV64_RS15310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBV64_RS15315	COG0328	RNA-DNA hybrid ribonuclease activity
NBV64_RS15320	COG2226	methyltransferase
NBV64_RS15325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NBV64_RS15330	COG0741	lytic transglycosylase activity
NBV64_RS15330	COG1388	LysM domain
NBV64_RS15340	COG2204	response regulator
NBV64_RS15345	COG4191	Histidine kinase
NBV64_RS15350	COG1301	dicarboxylic acid transport
NBV64_RS15360	COG1054	Belongs to the UPF0176 family
NBV64_RS15385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBV64_RS15405	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NBV64_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS15425	COG1877	trehalose-phosphatase activity
NBV64_RS15460	COG0604	alcohol dehydrogenase
NBV64_RS15470	COG1024	Enoyl-CoA hydratase
NBV64_RS15490	COG0604	alcohol dehydrogenase
NBV64_RS15495	COG1902	pentaerythritol trinitrate reductase activity
NBV64_RS15500	COG0583	DNA-binding transcription factor activity
NBV64_RS15560	COG0583	DNA-binding transcription factor activity
NBV64_RS15565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBV64_RS15570	COG1454	alcohol dehydrogenase
NBV64_RS15580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NBV64_RS15590	COG0583	DNA-binding transcription factor activity
NBV64_RS15605	COG1280	lysine exporter protein (LysE YggA)
NBV64_RS15625	COG1393	Belongs to the ArsC family
NBV64_RS15630	COG0431	NADPH-dependent FMN reductase
NBV64_RS15640	COG0642	Histidine kinase
NBV64_RS15690	COG3311	Transcriptional regulator
NBV64_RS15700	COG5377	YqaJ viral recombinase family
NBV64_RS15710	COG3620	sequence-specific DNA binding
NBV64_RS15735	COG1196	nuclear chromosome segregation
NBV64_RS15760	COG0582	viral genome integration into host DNA
NBV64_RS15770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBV64_RS15770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBV64_RS15775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBV64_RS15780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBV64_RS15785	COG1881	PFAM PEBP family protein
NBV64_RS15790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBV64_RS15795	COG0739	heme binding
NBV64_RS15800	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NBV64_RS15805	COG0316	Belongs to the HesB IscA family
NBV64_RS15815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NBV64_RS15820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NBV64_RS15825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBV64_RS15830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS15835	COG0312	modulator of DNA gyrase
NBV64_RS15840	COG3028	Belongs to the UPF0307 family
NBV64_RS15870	COG0745	RESPONSE REGULATOR receiver
NBV64_RS15870	COG2205	protein histidine kinase activity
NBV64_RS15870	COG4191	Histidine kinase
NBV64_RS15875	COG4566	intracellular signal transduction
NBV64_RS15880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBV64_RS15910	COG0762	integral membrane protein
NBV64_RS15915	COG2169	Transcriptional regulator
NBV64_RS15915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NBV64_RS15920	COG3133	Outer membrane lipoprotein
NBV64_RS15925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBV64_RS15940	COG0439	Biotin carboxylase
NBV64_RS15945	COG0511	ligase activity, forming carbon-carbon bonds
NBV64_RS15950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NBV64_RS15960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NBV64_RS15965	COG3150	esterase
NBV64_RS15980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NBV64_RS15985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NBV64_RS15995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NBV64_RS16010	COG1678	Uncharacterized ACR, COG1678
NBV64_RS16025	COG0352	thiamine-phosphate diphosphorylase activity
NBV64_RS16030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NBV64_RS16045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NBV64_RS16055	COG3237	CsbD-like
NBV64_RS16060	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NBV64_RS16065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NBV64_RS16070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBV64_RS16075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NBV64_RS16100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NBV64_RS16115	COG1126	abc transporter atp-binding protein
NBV64_RS16120	COG0765	amino acid transport
NBV64_RS16125	COG4597	amino acid ABC transporter
NBV64_RS16130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBV64_RS16135	COG2884	Cell division ATP-binding protein ftsE
NBV64_RS16140	COG2177	Part of the ABC transporter FtsEX involved in
NBV64_RS16150	COG0772	Belongs to the SEDS family
NBV64_RS16155	COG0768	penicillin binding
NBV64_RS16165	COG1792	Involved in formation and maintenance of cell shape
NBV64_RS16170	COG1077	Cell shape determining protein MreB Mrl
NBV64_RS16175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBV64_RS16180	COG0154	amidase activity
NBV64_RS16185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBV64_RS16190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBV64_RS16195	COG0583	DNA-binding transcription factor activity
NBV64_RS16200	COG2259	Doxx family
NBV64_RS16205	COG3384	dioxygenase
NBV64_RS16225	COG1846	Transcriptional regulator
NBV64_RS16230	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS16245	COG1024	Enoyl-CoA hydratase
NBV64_RS16255	COG3604	Transcriptional regulator
NBV64_RS16275	COG1309	transcriptional regulator
NBV64_RS16290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NBV64_RS16315	COG3046	protein related to deoxyribodipyrimidine photolyase
NBV64_RS16325	COG1090	epimerase
NBV64_RS16330	COG0786	glutamate:sodium symporter activity
NBV64_RS16335	COG0142	geranyltranstransferase activity
NBV64_RS16345	COG0494	nUDIX hydrolase
NBV64_RS16350	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NBV64_RS16375	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NBV64_RS16380	COG0237	dephospho-CoA kinase activity
NBV64_RS16395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NBV64_RS16400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NBV64_RS16410	COG0477	Major facilitator Superfamily
NBV64_RS16425	COG4206	TonB-dependent receptor
NBV64_RS16430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NBV64_RS16445	COG1595	DNA-templated transcription, initiation
NBV64_RS16455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBV64_RS16475	COG0598	Magnesium transport protein CorA
NBV64_RS16490	COG2022	thiamine diphosphate biosynthetic process
NBV64_RS16495	COG0351	phosphomethylpyrimidine kinase
NBV64_RS16500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBV64_RS16505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NBV64_RS16510	COG1538	Outer membrane efflux protein
NBV64_RS16515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NBV64_RS16525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NBV64_RS16540	COG2226	methyltransferase
NBV64_RS16545	COG0745	RESPONSE REGULATOR receiver
NBV64_RS16560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NBV64_RS16565	COG1984	allophanate hydrolase subunit 2
NBV64_RS16570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NBV64_RS16575	COG1238	metal cluster binding
NBV64_RS16605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBV64_RS16610	COG4988	ABC transporter
NBV64_RS16620	COG1294	oxidase, subunit
NBV64_RS16625	COG1271	oxidase subunit
NBV64_RS16640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NBV64_RS16655	COG1137	ATPase activity
NBV64_RS16665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBV64_RS16670	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NBV64_RS16675	COG1660	Displays ATPase and GTPase activities
NBV64_RS16680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NBV64_RS16685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBV64_RS16690	COG0792	nuclease activity
NBV64_RS16695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NBV64_RS16710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NBV64_RS16730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NBV64_RS16735	COG0793	Belongs to the peptidase S41A family
NBV64_RS16745	COG0588	phosphoglycerate mutase activity
NBV64_RS16750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBV64_RS16760	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NBV64_RS16765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NBV64_RS16770	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS16775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NBV64_RS16780	COG1040	competence protein
NBV64_RS16785	COG2226	methyltransferase
NBV64_RS16790	COG4771	TonB-dependent receptor
NBV64_RS16795	COG0745	RESPONSE REGULATOR receiver
NBV64_RS16810	COG2204	response regulator
NBV64_RS16830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NBV64_RS16845	COG3473	Maleate cis-trans isomerase
NBV64_RS16860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NBV64_RS16900	COG1215	transferase activity, transferring glycosyl groups
NBV64_RS16910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NBV64_RS16915	COG3307	-O-antigen
NBV64_RS16925	COG1088	dTDP-glucose 4,6-dehydratase activity
NBV64_RS16930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NBV64_RS16950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NBV64_RS16960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBV64_RS16965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBV64_RS16970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBV64_RS16985	COG0356	it plays a direct role in the translocation of protons across the membrane
NBV64_RS16995	COG1024	Enoyl-CoA hydratase
NBV64_RS17010	COG0037	tRNA processing
NBV64_RS17015	COG0163	prenyltransferase activity
NBV64_RS17020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NBV64_RS17025	COG2890	protein-(glutamine-N5) methyltransferase activity
NBV64_RS17075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBV64_RS17105	COG0811	peptide transport
NBV64_RS17120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NBV64_RS17125	COG2264	protein methyltransferase activity
NBV64_RS17140	COG3180	Ammonia monooxygenase
NBV64_RS17160	COG5002	protein histidine kinase activity
NBV64_RS17175	COG0477	Major facilitator Superfamily
NBV64_RS17180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBV64_RS17195	COG0437	4 iron, 4 sulfur cluster binding
NBV64_RS17200	COG2864	formate dehydrogenase
NBV64_RS17210	COG1921	L-seryl-tRNASec selenium transferase activity
NBV64_RS17215	COG3276	selenocysteine insertion sequence binding
NBV64_RS17225	COG1476	TRANSCRIPTIONal
NBV64_RS17240	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS17250	COG4771	TonB-dependent receptor
NBV64_RS17260	COG0709	Synthesizes selenophosphate from selenide and ATP
NBV64_RS17265	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NBV64_RS17270	COG0348	domain, Protein
NBV64_RS17270	COG3901	Regulator of nitric oxide reductase transcription
NBV64_RS17275	COG4263	nitrous-oxide reductase activity
NBV64_RS17290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NBV64_RS17305	COG0166	Belongs to the GPI family
NBV64_RS17330	COG1215	transferase activity, transferring glycosyl groups
NBV64_RS17340	COG0297	glycogen (starch) synthase activity
NBV64_RS17365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NBV64_RS17400	COG0156	8-amino-7-oxononanoate synthase activity
NBV64_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS17405	COG0604	alcohol dehydrogenase
NBV64_RS17405	COG3321	synthase
NBV64_RS17410	COG2233	PERMEase
NBV64_RS17415	COG0697	spore germination
NBV64_RS17420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS17425	COG0697	spore germination
NBV64_RS17445	COG2885	chlorophyll binding
NBV64_RS17540	COG0183	Belongs to the thiolase family
NBV64_RS17545	COG1250	3-hydroxyacyl-CoA dehydrogenase
NBV64_RS17545	COG1024	Enoyl-CoA hydratase
NBV64_RS17560	COG1127	ABC transporter
NBV64_RS17565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NBV64_RS17570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NBV64_RS17585	COG1131	(ABC) transporter
NBV64_RS17590	COG0842	Transport permease protein
NBV64_RS17600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBV64_RS17610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NBV64_RS17615	COG0131	Imidazoleglycerol-phosphate dehydratase
NBV64_RS17625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NBV64_RS17630	COG0107	imidazoleglycerol-phosphate synthase activity
NBV64_RS17640	COG0140	phosphoribosyl-ATP diphosphatase activity
NBV64_RS17645	COG0537	adenosine 5'-monophosphoramidase activity
NBV64_RS17650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NBV64_RS17655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NBV64_RS17665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NBV64_RS17675	COG1970	mechanosensitive ion channel activity
NBV64_RS17680	COG0723	plastoquinol--plastocyanin reductase activity
NBV64_RS17685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NBV64_RS17690	COG2857	Cytochrome c1
NBV64_RS17695	COG0625	glutathione transferase activity
NBV64_RS17700	COG2969	positive regulation of protein catabolic process
NBV64_RS17705	COG4208	sulfate ABC transporter
NBV64_RS17710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NBV64_RS17715	COG4150	thiosulfate binding
NBV64_RS17730	COG3119	arylsulfatase activity
NBV64_RS17750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBV64_RS17770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NBV64_RS17775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NBV64_RS17785	COG2084	Dehydrogenase
NBV64_RS17790	COG0129	dihydroxy-acid dehydratase activity
NBV64_RS17795	COG1802	Transcriptional regulator
NBV64_RS17800	COG1522	sequence-specific DNA binding
NBV64_RS17810	COG3483	tryptophan 2,3-dioxygenase activity
NBV64_RS17830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NBV64_RS17835	COG0656	L-ascorbic acid biosynthetic process
NBV64_RS17845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NBV64_RS17850	COG3706	GGDEF domain
NBV64_RS17855	COG2226	methyltransferase
NBV64_RS17880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NBV64_RS17885	COG0583	DNA-binding transcription factor activity
NBV64_RS17890	COG0477	Major facilitator Superfamily
NBV64_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
NBV64_RS17905	COG1335	isochorismatase
NBV64_RS17925	COG2823	Periplasmic or secreted lipoprotein
NBV64_RS17935	COG3284	Transcriptional regulator
NBV64_RS17965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBV64_RS17970	COG0583	DNA-binding transcription factor activity
NBV64_RS18005	COG1595	DNA-templated transcription, initiation
NBV64_RS18015	COG1522	sequence-specific DNA binding
NBV64_RS18025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBV64_RS18045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NBV64_RS18085	COG0109	protoheme IX farnesyltransferase activity
NBV64_RS18105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NBV64_RS18125	COG3568	Endonuclease Exonuclease Phosphatase
NBV64_RS18130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NBV64_RS18155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBV64_RS18165	COG1228	amidohydrolase
NBV64_RS18185	COG2986	histidine ammonia-lyase
NBV64_RS18190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NBV64_RS18215	COG0583	DNA-binding transcription factor activity
NBV64_RS18225	COG0789	Transcriptional regulator
NBV64_RS18235	COG1017	nitric oxide dioxygenase activity
NBV64_RS18235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBV64_RS18255	COG2365	Tyrosine phosphatase family
NBV64_RS18260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NBV64_RS18280	COG2423	ornithine cyclodeaminase activity
NBV64_RS18330	COG3069	C4-dicarboxylate transmembrane transporter activity
NBV64_RS18340	COG1802	Transcriptional regulator
NBV64_RS18345	COG1309	transcriptional regulator
NBV64_RS18350	COG2814	Major facilitator Superfamily
NBV64_RS18365	COG2814	Major facilitator Superfamily
NBV64_RS18370	COG0251	oxidation-reduction process
NBV64_RS18375	COG3181	Tripartite tricarboxylate transporter family receptor
NBV64_RS18380	COG0179	Fumarylacetoacetate (FAA) hydrolase
NBV64_RS18385	COG2186	Transcriptional regulator
NBV64_RS18395	COG2814	Major facilitator Superfamily
NBV64_RS18405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NBV64_RS18410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NBV64_RS18415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NBV64_RS18435	COG5001	Diguanylate cyclase
NBV64_RS18435	COG5002	protein histidine kinase activity
NBV64_RS18440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NBV64_RS18445	COG1333	cytochrome c biogenesis protein
NBV64_RS18455	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NBV64_RS18460	COG0113	porphobilinogen synthase activity
NBV64_RS18465	COG4232	protein-disulfide reductase activity
NBV64_RS18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NBV64_RS18490	COG0203	ribosomal protein L17
NBV64_RS18495	COG0202	RNA polymerase activity
NBV64_RS18500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBV64_RS18505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBV64_RS18510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBV64_RS18515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NBV64_RS18525	COG0201	protein transport
NBV64_RS18530	COG0200	Binds to the 23S rRNA
NBV64_RS18535	COG1841	ribosomal large subunit assembly
NBV64_RS18540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBV64_RS18545	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBV64_RS18550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBV64_RS18555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBV64_RS18560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBV64_RS18565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBV64_RS18570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBV64_RS18575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBV64_RS18615	COG1538	Outer membrane efflux protein
NBV64_RS18630	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS18635	COG0183	Belongs to the thiolase family
NBV64_RS18645	COG2067	long-chain fatty acid transport protein
NBV64_RS18660	COG0318	PFAM AMP-dependent synthetase and ligase
NBV64_RS18665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NBV64_RS18670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NBV64_RS18675	COG1648	precorrin-2 dehydrogenase activity
NBV64_RS18675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBV64_RS18690	COG1116	anion transmembrane transporter activity
NBV64_RS18695	COG1960	acyl-CoA dehydrogenase activity
NBV64_RS18710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBV64_RS18715	COG0255	Belongs to the universal ribosomal protein uL29 family
NBV64_RS18720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBV64_RS18725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBV64_RS18730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBV64_RS18735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBV64_RS18740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBV64_RS18745	COG0089	rRNA binding
NBV64_RS18750	COG0088	Forms part of the polypeptide exit tunnel
NBV64_RS18755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBV64_RS18760	COG4175	Glycine betaine
NBV64_RS18765	COG4176	ABC-type proline glycine betaine transport system permease component
NBV64_RS18770	COG0051	transcription antitermination factor activity, RNA binding
NBV64_RS18775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBV64_RS18780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBV64_RS18785	COG0049	tRNA binding
NBV64_RS18790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBV64_RS18820	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NBV64_RS18825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBV64_RS18830	COG0085	RNA polymerase activity
NBV64_RS18835	COG0222	ribosome binding
NBV64_RS18840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBV64_RS18845	COG0081	regulation of translation
NBV64_RS18870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBV64_RS18890	COG1475	DNA binding
NBV64_RS18895	COG1192	Involved in chromosome partitioning
NBV64_RS18900	COG0357	Ribosomal RNA small subunit methyltransferase G
NBV64_RS18905	COG0445	tRNA wobble uridine modification
NBV64_RS18910	COG0436	Aminotransferase
NBV64_RS18920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NBV64_RS18925	COG3706	GGDEF domain
NBV64_RS18930	COG0688	phosphatidylethanolamine metabolic process
NBV64_RS18940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NBV64_RS18985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBV64_RS19020	COG0753	catalase activity
NBV64_RS19025	COG0706	membrane insertase activity
NBV64_RS19030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NBV64_RS19035	COG0594	ribonuclease P activity
NBV64_RS19040	COG0230	Belongs to the bacterial ribosomal protein bL34 family