locus-tag	class	description
ABO_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABO_RS00035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABO_RS00040	COG0751	glycine-tRNA ligase activity
ABO_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
ABO_RS00050	COG2818	Glycosylase
ABO_RS00070	COG1160	GTP binding
ABO_RS00075	COG1846	Transcriptional regulator
ABO_RS00090	COG1566	PFAM secretion protein HlyD family protein
ABO_RS00110	COG1960	acyl-CoA dehydrogenase activity
ABO_RS00120	COG5285	phytanoyl-CoA dioxygenase
ABO_RS00135	COG0435	Glutathione S-transferase
ABO_RS00140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABO_RS00145	COG0583	DNA-binding transcription factor activity
ABO_RS00165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABO_RS00180	COG0540	Belongs to the ATCase OTCase family
ABO_RS00185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABO_RS00190	COG3038	cytochrome b561
ABO_RS00195	COG2353	YceI-like domain
ABO_RS00225	COG0678	peroxiredoxin activity
ABO_RS00245	COG1666	GTP binding
ABO_RS00260	COG0519	Catalyzes the synthesis of GMP from XMP
ABO_RS00260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABO_RS00270	COG0110	maltose O-acetyltransferase activity
ABO_RS00290	COG4399	Belongs to the UPF0754 family
ABO_RS00310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABO_RS00310	COG4221	oxidoreductase activity
ABO_RS00310	COG3321	synthase
ABO_RS00310	COG0604	alcohol dehydrogenase
ABO_RS00320	COG1944	ATP diphosphatase activity
ABO_RS00325	COG2703	oxygen carrier activity
ABO_RS00335	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABO_RS00340	COG0277	FAD linked oxidase domain protein
ABO_RS00345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABO_RS00380	COG0475	glutathione-regulated potassium exporter activity
ABO_RS00380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABO_RS00385	COG4773	Receptor
ABO_RS00395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABO_RS00405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABO_RS00425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ABO_RS00440	COG1309	transcriptional regulator
ABO_RS00445	COG0429	hydrolase of the alpha beta-hydrolase fold
ABO_RS00450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABO_RS00480	COG0330	HflC and HflK could
ABO_RS00495	COG3038	cytochrome b561
ABO_RS00515	COG2201	protein-glutamate methylesterase activity
ABO_RS00530	COG0840	transmembrane signaling receptor activity
ABO_RS00550	COG0189	ligase activity
ABO_RS00560	COG1678	Uncharacterized ACR, COG1678
ABO_RS00565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABO_RS00585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABO_RS00590	COG0583	DNA-binding transcription factor activity
ABO_RS00610	COG3239	Fatty acid desaturase
ABO_RS00620	COG3121	Chaperone
ABO_RS00625	COG3188	usher protein
ABO_RS00635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABO_RS00640	COG0569	domain protein
ABO_RS00645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABO_RS00650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABO_RS00655	COG0242	peptide deformylase activity
ABO_RS00665	COG0758	DNA mediated transformation
ABO_RS00670	COG0009	L-threonylcarbamoyladenylate synthase
ABO_RS00675	COG0408	coproporphyrinogen oxidase activity
ABO_RS00680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABO_RS00695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABO_RS00705	COG0339	signal peptide processing
ABO_RS00735	COG0583	DNA-binding transcription factor activity
ABO_RS00740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABO_RS00745	COG1024	Enoyl-CoA hydratase
ABO_RS00745	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABO_RS00765	COG1278	Cold shock
ABO_RS00780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ABO_RS00785	COG1121	(ABC) transporter
ABO_RS00790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABO_RS00795	COG0534	Mate efflux family protein
ABO_RS00800	COG2199	diguanylate cyclase activity
ABO_RS00815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABO_RS00820	COG1773	rubredoxin
ABO_RS00825	COG3161	chorismate lyase activity
ABO_RS00830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ABO_RS00845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABO_RS00850	COG0583	DNA-binding transcription factor activity
ABO_RS00860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABO_RS00865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABO_RS00885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABO_RS00890	COG1758	RNA polymerase activity
ABO_RS00895	COG0194	GDP metabolic process
ABO_RS00900	COG3608	succinylglutamate desuccinylase aspartoacylase
ABO_RS00905	COG0129	dihydroxy-acid dehydratase activity
ABO_RS00925	COG0318	PFAM AMP-dependent synthetase and ligase
ABO_RS00930	COG1960	acyl-CoA dehydrogenase activity
ABO_RS00995	COG1309	transcriptional regulator
ABO_RS01005	COG0633	Ferredoxin
ABO_RS01030	COG1561	YicC-like family, N-terminal region
ABO_RS01035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABO_RS01040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABO_RS01050	COG1309	transcriptional regulator
ABO_RS01055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABO_RS01065	COG0756	dUTP diphosphatase activity
ABO_RS01070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABO_RS01075	COG2003	Belongs to the UPF0758 family
ABO_RS01080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABO_RS01085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABO_RS01105	COG4964	Belongs to the GSP D family
ABO_RS01180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABO_RS01210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABO_RS01240	COG0789	Transcriptional regulator
ABO_RS01250	COG3530	Putative quorum-sensing-regulated virulence factor
ABO_RS01260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABO_RS01265	COG0577	efflux transmembrane transporter activity
ABO_RS01265	COG1136	(ABC) transporter
ABO_RS01270	COG1538	Outer membrane efflux protein
ABO_RS01275	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABO_RS01285	COG0183	Belongs to the thiolase family
ABO_RS01290	COG0488	(ABC) transporter
ABO_RS01310	COG0545	Peptidyl-prolyl cis-trans isomerase
ABO_RS01320	COG1346	cytolysis
ABO_RS01330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABO_RS01340	COG2918	glutathione biosynthetic process
ABO_RS01345	COG2183	response to ionizing radiation
ABO_RS01355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABO_RS01360	COG1566	PFAM secretion protein HlyD family protein
ABO_RS01380	COG0569	domain protein
ABO_RS01385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABO_RS01390	COG1295	ribonuclease BN
ABO_RS01395	COG1252	NADH dehydrogenase
ABO_RS01400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABO_RS01405	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABO_RS01410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABO_RS01415	COG1011	Hydrolase
ABO_RS01420	COG0494	nUDIX hydrolase
ABO_RS01425	COG1218	3'(2'),5'-bisphosphate nucleotidase
ABO_RS01435	COG2072	flavoprotein involved in K transport
ABO_RS01480	COG0488	(ABC) transporter
ABO_RS01495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABO_RS01505	COG0473	3-isopropylmalate dehydrogenase activity
ABO_RS01510	COG1131	(ABC) transporter
ABO_RS01515	COG0842	Transport permease protein
ABO_RS01520	COG3781	membrane
ABO_RS01525	COG3268	Saccharopine dehydrogenase
ABO_RS01535	COG0259	pyridoxamine-phosphate oxidase activity
ABO_RS01550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABO_RS01555	COG0733	neurotransmitter:sodium symporter activity
ABO_RS01560	COG2914	Belongs to the UPF0125 (RnfH) family
ABO_RS01575	COG0497	DNA recombination
ABO_RS01585	COG1420	regulation of RNA biosynthetic process
ABO_RS01590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABO_RS01595	COG0443	Heat shock 70 kDa protein
ABO_RS01600	COG0484	heat shock protein binding
ABO_RS01605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABO_RS01610	COG0505	Belongs to the CarA family
ABO_RS01615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABO_RS01630	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ABO_RS01635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABO_RS01640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABO_RS01645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABO_RS01650	COG0149	triose-phosphate isomerase activity
ABO_RS01670	COG0779	Required for maturation of 30S ribosomal subunits
ABO_RS01675	COG2251	uridine kinase activity
ABO_RS01675	COG0195	Participates in both transcription termination and antitermination
ABO_RS01680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABO_RS01685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABO_RS01695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABO_RS01700	COG1185	polyribonucleotide nucleotidyltransferase activity
ABO_RS01705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABO_RS01710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABO_RS01715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABO_RS01720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABO_RS01725	COG1428	Deoxynucleoside kinase
ABO_RS01730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABO_RS01745	COG3852	Histidine kinase
ABO_RS01755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABO_RS01765	COG0436	Aminotransferase
ABO_RS01770	COG1489	DNA binding
ABO_RS01775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABO_RS01785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABO_RS01790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABO_RS01805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABO_RS01810	COG0352	thiamine-phosphate diphosphorylase activity
ABO_RS01815	COG0352	thiamine-phosphate diphosphorylase activity
ABO_RS01815	COG0351	phosphomethylpyrimidine kinase
ABO_RS01815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABO_RS01820	COG1981	membrane
ABO_RS01830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABO_RS01845	COG0316	Belongs to the HesB IscA family
ABO_RS01855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABO_RS01860	COG0739	heme binding
ABO_RS01865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABO_RS01905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABO_RS01935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABO_RS01955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABO_RS01960	COG0081	regulation of translation
ABO_RS01965	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABO_RS01970	COG0222	ribosome binding
ABO_RS01975	COG0085	RNA polymerase activity
ABO_RS01980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABO_RS01985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABO_RS01990	COG0049	tRNA binding
ABO_RS01995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABO_RS02000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABO_RS02010	COG1215	transferase activity, transferring glycosyl groups
ABO_RS02015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABO_RS02060	COG0662	Cupin 2, conserved barrel domain protein
ABO_RS02060	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ABO_RS02065	COG0051	transcription antitermination factor activity, RNA binding
ABO_RS02070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABO_RS02075	COG0088	Forms part of the polypeptide exit tunnel
ABO_RS02080	COG0089	rRNA binding
ABO_RS02085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABO_RS02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABO_RS02095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABO_RS02100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABO_RS02105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABO_RS02110	COG0255	Belongs to the universal ribosomal protein uL29 family
ABO_RS02115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABO_RS02120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABO_RS02125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABO_RS02130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABO_RS02135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABO_RS02140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABO_RS02145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABO_RS02150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABO_RS02155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABO_RS02160	COG1841	ribosomal large subunit assembly
ABO_RS02165	COG0200	Binds to the 23S rRNA
ABO_RS02175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABO_RS02180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABO_RS02185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABO_RS02190	COG0202	RNA polymerase activity
ABO_RS02195	COG0203	ribosomal protein L17
ABO_RS02225	COG2814	Major facilitator Superfamily
ABO_RS02240	COG3031	protein transport across the cell outer membrane
ABO_RS02260	COG2267	carboxylic ester hydrolase activity
ABO_RS02265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABO_RS02280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABO_RS02300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABO_RS02340	COG0142	geranyltranstransferase activity
ABO_RS02345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABO_RS02350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABO_RS02355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABO_RS02360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABO_RS02365	COG0268	Binds directly to 16S ribosomal RNA
ABO_RS02370	COG0728	peptidoglycan biosynthetic process
ABO_RS02375	COG0196	riboflavin kinase activity
ABO_RS02380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABO_RS02390	COG1047	Peptidyl-prolyl cis-trans
ABO_RS02395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABO_RS02400	COG4969	Belongs to the N-Me-Phe pilin family
ABO_RS02490	COG0028	Belongs to the TPP enzyme family
ABO_RS02510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABO_RS02515	COG1183	phosphatidylcholine synthase activity
ABO_RS02540	COG1597	lipid kinase activity
ABO_RS02560	COG0525	valine-tRNA ligase activity
ABO_RS02575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABO_RS02580	COG0795	lipopolysaccharide-transporting ATPase activity
ABO_RS02585	COG0795	lipopolysaccharide-transporting ATPase activity
ABO_RS02600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABO_RS02605	COG0343	queuine tRNA-ribosyltransferase activity
ABO_RS02610	COG1862	Preprotein translocase
ABO_RS02615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABO_RS02630	COG0436	Aminotransferase
ABO_RS02635	COG0154	amidase activity
ABO_RS02650	COG0473	3-isopropylmalate dehydrogenase activity
ABO_RS02655	COG1012	belongs to the aldehyde dehydrogenase family
ABO_RS02665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ABO_RS02675	COG0012	GTP binding
ABO_RS02680	COG0193	aminoacyl-tRNA hydrolase activity
ABO_RS02685	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABO_RS02690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABO_RS02700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABO_RS02705	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABO_RS02715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABO_RS02720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABO_RS02725	COG2890	protein-(glutamine-N5) methyltransferase activity
ABO_RS02740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABO_RS02745	COG0154	amidase activity
ABO_RS02750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABO_RS02755	COG1077	Cell shape determining protein MreB Mrl
ABO_RS02760	COG1792	Involved in formation and maintenance of cell shape
ABO_RS02765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ABO_RS02770	COG0424	maF-like protein
ABO_RS02780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABO_RS02785	COG0312	modulator of DNA gyrase
ABO_RS02800	COG3028	Belongs to the UPF0307 family
ABO_RS02805	COG0312	modulator of DNA gyrase
ABO_RS02810	COG2239	Acts as a magnesium transporter
ABO_RS02820	COG2181	nitrate reductase activity
ABO_RS02825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ABO_RS02830	COG1140	nitrate reductase beta subunit
ABO_RS02835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ABO_RS02840	COG2223	nitrite transmembrane transporter activity
ABO_RS02845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABO_RS02850	COG1660	Displays ATPase and GTPase activities
ABO_RS02865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABO_RS02870	COG1137	ATPase activity
ABO_RS02885	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABO_RS02905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABO_RS02910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABO_RS02915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABO_RS02920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABO_RS02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABO_RS02935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABO_RS02940	COG1597	lipid kinase activity
ABO_RS02950	COG2945	thiolester hydrolase activity
ABO_RS02955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABO_RS02960	COG1960	acyl-CoA dehydrogenase activity
ABO_RS02975	COG0667	Aldo Keto reductase
ABO_RS02980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABO_RS02985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABO_RS02990	COG0723	plastoquinol--plastocyanin reductase activity
ABO_RS02995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABO_RS03000	COG2857	Cytochrome c1
ABO_RS03005	COG0625	glutathione transferase activity
ABO_RS03010	COG2969	positive regulation of protein catabolic process
ABO_RS03015	COG2823	Periplasmic or secreted lipoprotein
ABO_RS03025	COG0792	nuclease activity
ABO_RS03030	COG3107	peptidoglycan biosynthetic process
ABO_RS03040	COG0426	domain, Protein
ABO_RS03040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABO_RS03045	COG2001	Belongs to the MraZ family
ABO_RS03050	COG0275	rRNA processing
ABO_RS03065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABO_RS03070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABO_RS03075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABO_RS03080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABO_RS03085	COG0772	Belongs to the SEDS family
ABO_RS03090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABO_RS03095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABO_RS03100	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABO_RS03105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABO_RS03120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABO_RS03130	COG0739	heme binding
ABO_RS03135	COG0653	protein targeting
ABO_RS03145	COG0494	nUDIX hydrolase
ABO_RS03150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABO_RS03155	COG0237	dephospho-CoA kinase activity
ABO_RS03160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABO_RS03175	COG4969	Belongs to the N-Me-Phe pilin family
ABO_RS03190	COG1115	amino acid carrier protein
ABO_RS03225	COG0745	RESPONSE REGULATOR receiver
ABO_RS03230	COG2205	protein histidine kinase activity
ABO_RS03235	COG2096	Adenosyltransferase
ABO_RS03240	COG4206	TonB-dependent receptor
ABO_RS03245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABO_RS03255	COG2211	Major facilitator Superfamily
ABO_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS03270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABO_RS03275	COG0459	protein refolding
ABO_RS03295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABO_RS03320	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABO_RS03325	COG2315	Protein conserved in bacteria
ABO_RS03345	COG0183	Belongs to the thiolase family
ABO_RS03380	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ABO_RS03385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABO_RS03395	COG1611	Belongs to the LOG family
ABO_RS03405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABO_RS03415	COG2226	methyltransferase
ABO_RS03420	COG1733	regulation of RNA biosynthetic process
ABO_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS03465	COG0543	2 iron, 2 sulfur cluster binding
ABO_RS03465	COG0633	Ferredoxin
ABO_RS03495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABO_RS03500	COG2755	lipolytic protein G-D-S-L family
ABO_RS03500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ABO_RS03515	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ABO_RS03535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABO_RS03545	COG0705	Rhomboid family
ABO_RS03590	COG1451	nucleotide metabolic process
ABO_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
ABO_RS03660	COG0450	alkyl hydroperoxide reductase
ABO_RS03670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABO_RS03680	COG0745	RESPONSE REGULATOR receiver
ABO_RS03685	COG2205	protein histidine kinase activity
ABO_RS03690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABO_RS03705	COG3842	ATPase activity
ABO_RS03710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABO_RS03715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABO_RS03730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABO_RS03735	COG0450	alkyl hydroperoxide reductase
ABO_RS03740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABO_RS03745	COG0137	argininosuccinate synthase activity
ABO_RS03750	COG0346	lactoylglutathione lyase activity
ABO_RS03755	COG4067	protein conserved in archaea
ABO_RS03755	COG0189	ligase activity
ABO_RS03760	COG0189	ligase activity
ABO_RS03770	COG2046	Belongs to the sulfate adenylyltransferase family
ABO_RS03790	COG0513	Belongs to the DEAD box helicase family
ABO_RS03805	COG1192	Involved in chromosome partitioning
ABO_RS03815	COG0442	prolyl-tRNA aminoacylation
ABO_RS03830	COG0729	surface antigen
ABO_RS03835	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABO_RS03845	COG2226	methyltransferase
ABO_RS03865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABO_RS03870	COG0217	transcriptional regulatory protein
ABO_RS03875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ABO_RS03880	COG0632	four-way junction helicase activity
ABO_RS03885	COG2255	four-way junction helicase activity
ABO_RS03890	COG0824	Thioesterase
ABO_RS03910	COG0823	Involved in the tonB-independent uptake of proteins
ABO_RS03925	COG0602	queuosine metabolic process
ABO_RS03930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABO_RS03950	COG0789	Transcriptional regulator
ABO_RS03955	COG0415	Belongs to the DNA photolyase family
ABO_RS03970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABO_RS03975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABO_RS03980	COG4783	chaperone-mediated protein folding
ABO_RS03985	COG0425	Belongs to the sulfur carrier protein TusA family
ABO_RS03995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABO_RS04000	COG2716	regulation of RNA biosynthetic process
ABO_RS04005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABO_RS04015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABO_RS04020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABO_RS04050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ABO_RS04055	COG0047	phosphoribosylformylglycinamidine synthase activity
ABO_RS04055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABO_RS04065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABO_RS04070	COG2816	NAD+ diphosphatase activity
ABO_RS04075	COG2197	response regulator
ABO_RS04085	COG0494	nUDIX hydrolase
ABO_RS04100	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABO_RS04105	COG4536	flavin adenine dinucleotide binding
ABO_RS04115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABO_RS04120	COG0228	four-way junction DNA binding
ABO_RS04125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABO_RS04130	COG0336	Belongs to the RNA methyltransferase TrmD family
ABO_RS04135	COG0335	large ribosomal subunit rRNA binding
ABO_RS04140	COG2261	transglycosylase associated protein
ABO_RS04150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABO_RS04155	COG0436	Aminotransferase
ABO_RS04165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABO_RS04170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABO_RS04175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABO_RS04190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABO_RS04195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABO_RS04200	COG2264	protein methyltransferase activity
ABO_RS04205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABO_RS04230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABO_RS04245	COG5001	Diguanylate cyclase
ABO_RS04270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABO_RS04275	COG0642	Histidine kinase
ABO_RS04290	COG4977	sequence-specific DNA binding
ABO_RS04295	COG1960	acyl-CoA dehydrogenase activity
ABO_RS04305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABO_RS04315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABO_RS04320	COG4235	cytochrome complex assembly
ABO_RS04320	COG3088	subunit of a heme lyase
ABO_RS04330	COG0563	adenylate kinase activity
ABO_RS04350	COG3630	sodium ion export across plasma membrane
ABO_RS04355	COG5016	pyruvate
ABO_RS04355	COG0511	ligase activity, forming carbon-carbon bonds
ABO_RS04360	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABO_RS04385	COG0477	Major facilitator Superfamily
ABO_RS04395	COG1116	anion transmembrane transporter activity
ABO_RS04395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABO_RS04400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABO_RS04405	COG1116	anion transmembrane transporter activity
ABO_RS04435	COG3707	response regulator
ABO_RS04440	COG1116	anion transmembrane transporter activity
ABO_RS04440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABO_RS04445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABO_RS04450	COG0583	DNA-binding transcription factor activity
ABO_RS04460	COG4807	Protein conserved in bacteria
ABO_RS04475	COG2954	triphosphatase activity
ABO_RS04490	COG4133	protoheme IX ABC transporter activity
ABO_RS04510	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ABO_RS04515	COG0189	ligase activity
ABO_RS04520	COG0625	glutathione transferase activity
ABO_RS04540	COG1131	(ABC) transporter
ABO_RS04545	COG0842	Transport permease protein
ABO_RS04550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABO_RS04550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABO_RS04555	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABO_RS04575	COG0778	Nitroreductase
ABO_RS04630	COG0438	transferase activity, transferring glycosyl groups
ABO_RS04645	COG1943	Transposase
ABO_RS04650	COG4953	penicillin-binding protein 1C
ABO_RS04655	COG3383	formate dehydrogenase (NAD+) activity
ABO_RS04680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABO_RS04685	COG3206	protein involved in exopolysaccharide biosynthesis
ABO_RS04685	COG0489	protein tyrosine kinase activity
ABO_RS04690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABO_RS04700	COG1088	dTDP-glucose 4,6-dehydratase activity
ABO_RS04705	COG1091	dTDP-4-dehydrorhamnose reductase activity
ABO_RS04715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ABO_RS04745	COG0438	transferase activity, transferring glycosyl groups
ABO_RS04750	COG0438	transferase activity, transferring glycosyl groups
ABO_RS04755	COG0297	glycogen (starch) synthase activity
ABO_RS04770	COG0438	transferase activity, transferring glycosyl groups
ABO_RS04775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABO_RS04785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABO_RS04800	COG3273	potassium ion transport
ABO_RS04800	COG0471	metal ion transport
ABO_RS04805	COG0529	Catalyzes the synthesis of activated sulfate
ABO_RS04810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABO_RS04825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABO_RS04835	COG0166	Belongs to the GPI family
ABO_RS04845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABO_RS04860	COG1215	transferase activity, transferring glycosyl groups
ABO_RS04870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABO_RS04880	COG0436	Aminotransferase
ABO_RS04905	COG3115	cell septum assembly
ABO_RS04910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABO_RS04930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABO_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS04950	COG1960	acyl-CoA dehydrogenase activity
ABO_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS04985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABO_RS04995	COG1309	transcriptional regulator
ABO_RS05000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABO_RS05005	COG3089	Belongs to the UPF0270 family
ABO_RS05010	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ABO_RS05015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABO_RS05015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABO_RS05025	COG2205	protein histidine kinase activity
ABO_RS05025	COG0784	Response regulator, receiver
ABO_RS05025	COG5002	protein histidine kinase activity
ABO_RS05035	COG4106	trans-aconitate 2-methyltransferase activity
ABO_RS05040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABO_RS05080	COG0183	Belongs to the thiolase family
ABO_RS05085	COG1960	acyl-CoA dehydrogenase activity
ABO_RS05090	COG0318	PFAM AMP-dependent synthetase and ligase
ABO_RS05105	COG1960	acyl-CoA dehydrogenase activity
ABO_RS05110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABO_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS05125	COG1309	transcriptional regulator
ABO_RS05150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABO_RS05155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABO_RS05165	COG2267	carboxylic ester hydrolase activity
ABO_RS05170	COG0308	aminopeptidase N
ABO_RS05200	COG3130	regulation of translation
ABO_RS05205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABO_RS05205	COG0116	Belongs to the methyltransferase superfamily
ABO_RS05225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABO_RS05235	COG0589	response to stress
ABO_RS05265	COG1376	ErfK ybiS ycfS ynhG family protein
ABO_RS05270	COG1472	Belongs to the glycosyl hydrolase 3 family
ABO_RS05275	COG0668	transmembrane transport
ABO_RS05280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABO_RS05280	COG0037	tRNA processing
ABO_RS05290	COG1253	flavin adenine dinucleotide binding
ABO_RS05295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABO_RS05300	COG2081	HI0933 family
ABO_RS05320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABO_RS05325	COG1946	Acyl-CoA thioesterase
ABO_RS05330	COG1573	uracil-dna glycosylase
ABO_RS05340	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ABO_RS05345	COG1805	sodium ion transport
ABO_RS05360	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ABO_RS05365	COG2871	sodium ion transport
ABO_RS05370	COG1477	protein flavinylation
ABO_RS05390	COG0584	glycerophosphoryl diester phosphodiesterase
ABO_RS05400	COG0438	transferase activity, transferring glycosyl groups
ABO_RS05410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABO_RS05415	COG2957	Belongs to the agmatine deiminase family
ABO_RS05425	COG4591	ABC-type transport system involved in lipoprotein release permease component
ABO_RS05430	COG1136	(ABC) transporter
ABO_RS05445	COG0811	peptide transport
ABO_RS05450	COG0848	biopolymer transport protein
ABO_RS05455	COG1132	(ABC) transporter
ABO_RS05460	COG1663	tetraacyldisaccharide 4'-kinase activity
ABO_RS05465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABO_RS05470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABO_RS05475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABO_RS05480	COG1530	ribonuclease E activity
ABO_RS05490	COG0546	phosphoglycolate phosphatase activity
ABO_RS05495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABO_RS05495	COG0616	signal peptide processing
ABO_RS05500	COG0424	maF-like protein
ABO_RS05505	COG1399	metal-binding, possibly nucleic acid-binding protein
ABO_RS05510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABO_RS05515	COG0416	fatty acid biosynthetic process
ABO_RS05530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABO_RS05535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABO_RS05545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABO_RS05550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABO_RS05565	COG0084	hydrolase, TatD family'
ABO_RS05570	COG1322	Protein conserved in bacteria
ABO_RS05585	COG1104	cysteine desulfurase activity
ABO_RS05600	COG2815	serine threonine protein kinase
ABO_RS05600	COG0515	serine threonine protein kinase
ABO_RS05605	COG2223	nitrite transmembrane transporter activity
ABO_RS05610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABO_RS05610	COG2146	nitrite reductase [NAD(P)H] activity
ABO_RS05615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABO_RS05615	COG2146	nitrite reductase [NAD(P)H] activity
ABO_RS05620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABO_RS05625	COG0243	molybdopterin cofactor binding
ABO_RS05635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABO_RS05640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABO_RS05655	COG3153	acetyltransferase
ABO_RS05655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABO_RS05680	COG0583	DNA-binding transcription factor activity
ABO_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS05720	COG2308	Evidence 4 Homologs of previously reported genes of
ABO_RS05730	COG1305	Transglutaminase-like
ABO_RS05740	COG2194	sulfuric ester hydrolase activity
ABO_RS05780	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ABO_RS05785	COG2894	cell division
ABO_RS05790	COG0850	regulation of cytokinetic process
ABO_RS05795	COG1960	acyl-CoA dehydrogenase activity
ABO_RS05800	COG3118	belongs to the thioredoxin family
ABO_RS05810	COG0004	ammonium transporteR
ABO_RS05820	COG0746	molybdenum cofactor guanylyltransferase activity
ABO_RS05825	COG1199	ATP-dependent helicase activity
ABO_RS05830	COG1214	PFAM Peptidase M22, glycoprotease
ABO_RS05840	COG1968	undecaprenyl-diphosphatase activity
ABO_RS05845	COG0742	ribosomal rna small subunit methyltransferase
ABO_RS05850	COG2937	Belongs to the GPAT DAPAT family
ABO_RS05860	COG1012	belongs to the aldehyde dehydrogenase family
ABO_RS05870	COG1566	PFAM secretion protein HlyD family protein
ABO_RS05880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABO_RS05890	COG1393	Belongs to the ArsC family
ABO_RS05895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABO_RS05900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABO_RS05910	COG0052	Belongs to the universal ribosomal protein uS2 family
ABO_RS05915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABO_RS05920	COG0528	UMP kinase activity
ABO_RS05925	COG0233	cytoplasmic translational termination
ABO_RS05930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABO_RS05935	COG0575	Belongs to the CDS family
ABO_RS05940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABO_RS05960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABO_RS05965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABO_RS05970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABO_RS05975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABO_RS05980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABO_RS05990	COG0825	malonyl-CoA metabolic process
ABO_RS05995	COG0037	tRNA processing
ABO_RS06000	COG0514	ATP-dependent DNA helicase (RecQ)
ABO_RS06005	COG0504	CTP synthase activity
ABO_RS06010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABO_RS06015	COG0148	phosphopyruvate hydratase activity
ABO_RS06020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABO_RS06030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABO_RS06035	COG0585	pseudouridine synthase activity
ABO_RS06040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABO_RS06055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABO_RS06070	COG1454	alcohol dehydrogenase
ABO_RS06075	COG0824	Thioesterase
ABO_RS06080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABO_RS06090	COG0501	Belongs to the peptidase M48B family
ABO_RS06095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABO_RS06105	COG0436	Aminotransferase
ABO_RS06115	COG0672	)-iron permease
ABO_RS06130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABO_RS06140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABO_RS06140	COG0316	Belongs to the HesB IscA family
ABO_RS06150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABO_RS06165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABO_RS06190	COG1881	PFAM PEBP family protein
ABO_RS06215	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABO_RS06220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABO_RS06230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABO_RS06235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABO_RS06255	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABO_RS06260	COG0740	serine-type endopeptidase activity
ABO_RS06265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABO_RS06270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABO_RS06285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABO_RS06295	COG4172	Belongs to the ABC transporter superfamily
ABO_RS06300	COG4239	(ABC) transporter, permease
ABO_RS06305	COG4174	ABC transporter (Permease)
ABO_RS06310	COG4166	transmembrane transport
ABO_RS06315	COG4166	transmembrane transport
ABO_RS06320	COG1388	LysM domain
ABO_RS06320	COG0741	lytic transglycosylase activity
ABO_RS06325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABO_RS06335	COG0328	RNA-DNA hybrid ribonuclease activity
ABO_RS06345	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABO_RS06355	COG2816	NAD+ diphosphatase activity
ABO_RS06365	COG0616	signal peptide processing
ABO_RS06370	COG0604	alcohol dehydrogenase
ABO_RS06375	COG2084	Dehydrogenase
ABO_RS06380	COG3622	Belongs to the hyi family
ABO_RS06385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABO_RS06395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABO_RS06410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABO_RS06415	COG1960	acyl-CoA dehydrogenase activity
ABO_RS06435	COG0702	epimerase
ABO_RS06440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABO_RS06445	COG0517	IMP dehydrogenase activity
ABO_RS06445	COG0617	tRNA 3'-terminal CCA addition
ABO_RS06445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABO_RS06455	COG0039	L-malate dehydrogenase activity
ABO_RS06475	COG0271	Belongs to the BolA IbaG family
ABO_RS06480	COG1054	Belongs to the UPF0176 family
ABO_RS06495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABO_RS06530	COG1960	acyl-CoA dehydrogenase activity
ABO_RS06535	COG1960	acyl-CoA dehydrogenase activity
ABO_RS06540	COG0300	oxidoreductase activity
ABO_RS06545	COG0037	tRNA processing
ABO_RS06550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABO_RS06560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABO_RS06575	COG2850	peptidyl-arginine hydroxylation
ABO_RS06585	COG2915	High frequency lysogenization protein hflD homolog
ABO_RS06590	COG0482	sulfurtransferase activity
ABO_RS06600	COG0315	cyclic pyranopterin monophosphate synthase activity
ABO_RS06605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABO_RS06610	COG0314	molybdopterin synthase activity
ABO_RS06630	COG1278	Cold shock
ABO_RS06640	COG0542	response to heat
ABO_RS06645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABO_RS06650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABO_RS06655	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABO_RS06660	COG0492	ferredoxin-NADP+ reductase activity
ABO_RS06665	COG1674	ftsk spoiiie
ABO_RS06670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABO_RS06675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABO_RS06680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABO_RS06685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABO_RS06690	COG1648	precorrin-2 dehydrogenase activity
ABO_RS06690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABO_RS06695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABO_RS06710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ABO_RS06725	COG0003	Pfam Anion-transporting ATPase
ABO_RS06735	COG1966	Carbon starvation protein
ABO_RS06745	COG0322	excinuclease ABC activity
ABO_RS06770	COG5002	protein histidine kinase activity
ABO_RS06770	COG0784	Response regulator, receiver
ABO_RS06775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABO_RS06825	COG3156	type II secretion system protein K
ABO_RS06835	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ABO_RS06860	COG0668	transmembrane transport
ABO_RS06900	COG0700	Nucleoside recognition
ABO_RS06910	COG0598	Magnesium transport protein CorA
ABO_RS06925	COG3022	response to hydroperoxide
ABO_RS06935	COG0589	response to stress
ABO_RS06940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABO_RS06970	COG0348	domain, Protein
ABO_RS06975	COG2010	Cytochrome c
ABO_RS06990	COG3278	Belongs to the heme-copper respiratory oxidase family
ABO_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS06995	COG0604	alcohol dehydrogenase
ABO_RS06995	COG3321	synthase
ABO_RS07000	COG0583	DNA-binding transcription factor activity
ABO_RS07005	COG4974	Belongs to the 'phage' integrase family
ABO_RS07025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABO_RS07065	COG2132	Multicopper oxidase
ABO_RS07085	COG0789	Transcriptional regulator
ABO_RS07115	COG1742	UPF0060 membrane protein
ABO_RS07180	COG0542	response to heat
ABO_RS07185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABO_RS07195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABO_RS07205	COG0180	Tryptophanyl-tRNA synthetase
ABO_RS07210	COG0009	L-threonylcarbamoyladenylate synthase
ABO_RS07215	COG0613	PHP domain protein
ABO_RS07220	COG2917	probably involved in intracellular septation
ABO_RS07225	COG2350	Protein conserved in bacteria
ABO_RS07240	COG0204	Acyl-transferase
ABO_RS07260	COG4181	ATPase activity
ABO_RS07265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABO_RS07270	COG2814	Major facilitator Superfamily
ABO_RS07280	COG0789	Transcriptional regulator
ABO_RS07290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABO_RS07295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABO_RS07300	COG0277	FAD linked oxidase domain protein
ABO_RS07310	COG2885	chlorophyll binding
ABO_RS07315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABO_RS07315	COG2169	Transcriptional regulator
ABO_RS07320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABO_RS07350	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABO_RS07365	COG3339	Conserved Protein
ABO_RS07370	COG1192	Involved in chromosome partitioning
ABO_RS07380	COG0069	glutamate synthase activity
ABO_RS07385	COG1196	nuclear chromosome segregation
ABO_RS07385	COG0741	lytic transglycosylase activity
ABO_RS07385	COG0739	heme binding
ABO_RS07400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABO_RS07405	COG2079	MmgE PrpD family protein
ABO_RS07410	COG2828	Protein conserved in bacteria
ABO_RS07420	COG0372	Belongs to the citrate synthase family
ABO_RS07425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABO_RS07430	COG1802	Transcriptional regulator
ABO_RS07440	COG0560	Phosphoserine phosphatase
ABO_RS07480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ABO_RS07485	COG0235	Class ii aldolase
ABO_RS07490	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ABO_RS07495	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ABO_RS07500	COG2813	Specifically methylates the guanine in position
ABO_RS07510	COG1643	Atp-dependent helicase
ABO_RS07530	COG0714	Associated with various cellular activities
ABO_RS07545	COG1286	toxin biosynthetic process
ABO_RS07555	COG0285	dihydrofolate synthase activity
ABO_RS07560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABO_RS07565	COG0159	tryptophan synthase activity
ABO_RS07575	COG0135	phosphoribosylanthranilate isomerase activity
ABO_RS07580	COG0101	tRNA pseudouridine synthase activity
ABO_RS07590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABO_RS07600	COG0473	3-isopropylmalate dehydrogenase activity
ABO_RS07610	COG0066	3-isopropylmalate dehydratase activity
ABO_RS07615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABO_RS07630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABO_RS07650	COG0004	ammonium transporteR
ABO_RS07660	COG1301	dicarboxylic acid transport
ABO_RS07670	COG4221	oxidoreductase activity
ABO_RS07700	COG0708	Exodeoxyribonuclease III
ABO_RS07710	COG2062	phosphohistidine phosphatase, SixA
ABO_RS07715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABO_RS07720	COG0326	Molecular chaperone. Has ATPase activity
ABO_RS07735	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABO_RS07740	COG0045	succinate-CoA ligase (ADP-forming) activity
ABO_RS07760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABO_RS07765	COG1053	succinate dehydrogenase
ABO_RS07770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABO_RS07790	COG2084	Dehydrogenase
ABO_RS07830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABO_RS07840	COG0589	response to stress
ABO_RS07845	COG0659	secondary active sulfate transmembrane transporter activity
ABO_RS07855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABO_RS07865	COG2853	Lipoprotein
ABO_RS07875	COG3220	belongs to the UPF0276 family
ABO_RS07890	COG1643	Atp-dependent helicase
ABO_RS07910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ABO_RS07930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABO_RS07935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABO_RS08000	COG1254	Belongs to the acylphosphatase family
ABO_RS08005	COG1295	ribonuclease BN
ABO_RS08005	COG1959	2 iron, 2 sulfur cluster binding
ABO_RS08010	COG1393	Belongs to the ArsC family
ABO_RS08045	COG0714	Associated with various cellular activities
ABO_RS08050	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ABO_RS08055	COG3101	peptidyl-lysine hydroxylation
ABO_RS08095	COG2814	Major facilitator Superfamily
ABO_RS08100	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ABO_RS08105	COG0788	formyltetrahydrofolate deformylase activity
ABO_RS08120	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABO_RS08120	COG1024	Enoyl-CoA hydratase
ABO_RS08125	COG0183	Belongs to the thiolase family
ABO_RS08140	COG2840	Smr protein MutS2
ABO_RS08145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABO_RS08150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABO_RS08160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABO_RS08165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABO_RS08180	COG0717	Belongs to the dCTP deaminase family
ABO_RS08185	COG0489	protein tyrosine kinase activity
ABO_RS08230	COG2813	Specifically methylates the guanine in position
ABO_RS08235	COG0741	lytic transglycosylase activity
ABO_RS08240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABO_RS08260	COG1309	transcriptional regulator
ABO_RS08290	COG5002	protein histidine kinase activity
ABO_RS08290	COG2205	protein histidine kinase activity
ABO_RS08290	COG0784	Response regulator, receiver
ABO_RS08295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABO_RS08295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABO_RS08300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABO_RS08340	COG4657	Part of a membrane complex involved in electron transport
ABO_RS08345	COG2878	Part of a membrane complex involved in electron transport
ABO_RS08355	COG4658	electron transport chain
ABO_RS08360	COG4659	FMN binding
ABO_RS08365	COG4660	Part of a membrane complex involved in electron transport
ABO_RS08375	COG0786	glutamate:sodium symporter activity
ABO_RS08380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABO_RS08390	COG1739	Uncharacterized protein family UPF0029
ABO_RS08405	COG3956	TIGRFAM MazG family protein
ABO_RS08410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABO_RS08415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABO_RS08430	COG0784	Response regulator, receiver
ABO_RS08430	COG2205	protein histidine kinase activity
ABO_RS08430	COG5002	protein histidine kinase activity
ABO_RS08435	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABO_RS08445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABO_RS08450	COG0571	ribonuclease III activity
ABO_RS08465	COG0481	GTPase activity
ABO_RS08470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABO_RS08520	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABO_RS08520	COG1024	Enoyl-CoA hydratase
ABO_RS08525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABO_RS08530	COG3226	Transcriptional regulator
ABO_RS08535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABO_RS08550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABO_RS08555	COG1024	Enoyl-CoA hydratase
ABO_RS08555	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABO_RS08560	COG0183	Belongs to the thiolase family
ABO_RS08605	COG0789	Transcriptional regulator
ABO_RS08610	COG0484	heat shock protein binding
ABO_RS08615	COG0318	PFAM AMP-dependent synthetase and ligase
ABO_RS08625	COG0210	DNA helicase
ABO_RS08665	COG0577	efflux transmembrane transporter activity
ABO_RS08665	COG1136	(ABC) transporter
ABO_RS08680	COG0735	belongs to the Fur family
ABO_RS08710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABO_RS08715	COG0546	phosphoglycolate phosphatase activity
ABO_RS08725	COG0175	sulfate reduction
ABO_RS08765	COG0513	Belongs to the DEAD box helicase family
ABO_RS08770	COG3360	Dodecin
ABO_RS08775	COG0778	Nitroreductase
ABO_RS08795	COG1960	acyl-CoA dehydrogenase activity
ABO_RS08800	COG1960	acyl-CoA dehydrogenase activity
ABO_RS08815	COG1902	pentaerythritol trinitrate reductase activity
ABO_RS08815	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABO_RS08850	COG0183	Belongs to the thiolase family
ABO_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS08880	COG1309	transcriptional regulator
ABO_RS08885	COG2030	dehydratase
ABO_RS08890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ABO_RS08895	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ABO_RS08900	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABO_RS08900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABO_RS08905	COG3639	organic phosphonate transmembrane transporter activity
ABO_RS08915	COG0709	Synthesizes selenophosphate from selenide and ATP
ABO_RS08930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ABO_RS08935	COG1196	nuclear chromosome segregation
ABO_RS08935	COG3264	Mechanosensitive ion channel
ABO_RS08960	COG1901	pseudouridine methyltransferase
ABO_RS08975	COG0488	(ABC) transporter
ABO_RS08990	COG0284	orotidine-5'-phosphate decarboxylase activity
ABO_RS09005	COG0776	regulation of translation
ABO_RS09015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABO_RS09020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABO_RS09025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABO_RS09030	COG0077	Prephenate dehydratase
ABO_RS09030	COG1605	Chorismate mutase
ABO_RS09035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABO_RS09045	COG0402	S-adenosylhomocysteine deaminase activity
ABO_RS09055	COG0546	phosphoglycolate phosphatase activity
ABO_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS09115	COG2983	Belongs to the UPF0260 family
ABO_RS09120	COG3100	YcgL domain-containing protein
ABO_RS09125	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ABO_RS09130	COG0588	phosphoglycerate mutase activity
ABO_RS09140	COG1960	acyl-CoA dehydrogenase activity
ABO_RS09145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABO_RS09150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABO_RS09180	COG1695	Transcriptional regulator
ABO_RS09200	COG1819	glycosyl
ABO_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABO_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABO_RS09215	COG2801	Transposase and inactivated derivatives
ABO_RS09235	COG0427	acetyl-CoA hydrolase
ABO_RS09245	COG0523	cobalamin synthesis protein
ABO_RS09250	COG0418	dihydroorotase activity
ABO_RS09260	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ABO_RS09265	COG0527	aspartate kinase activity
ABO_RS09270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABO_RS09280	COG2137	regulation of response to DNA damage stimulus
ABO_RS09285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABO_RS09290	COG1546	Belongs to the CinA family
ABO_RS09295	COG0217	transcriptional regulatory protein
ABO_RS09310	COG1021	2,3-dihydroxybenzoate-AMP ligase
ABO_RS09320	COG2963	transposase activity
ABO_RS09325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABO_RS09330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABO_RS09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABO_RS09365	COG1509	lysine 2,3-aminomutase activity
ABO_RS09370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABO_RS09375	COG1074	ATP-dependent DNA helicase activity
ABO_RS09380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABO_RS09385	COG3784	Protein of unknown function (DUF1318)
ABO_RS09400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ABO_RS09415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABO_RS09420	COG0732	type I restriction modification DNA specificity domain
ABO_RS09425	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ABO_RS09435	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ABO_RS09460	COG0776	regulation of translation
ABO_RS09465	COG0072	phenylalanine-tRNA ligase activity
ABO_RS09470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABO_RS09475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABO_RS09480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABO_RS09485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABO_RS09495	COG0492	ferredoxin-NADP+ reductase activity
ABO_RS09510	COG0842	Transport permease protein
ABO_RS09515	COG0842	Transport permease protein
ABO_RS09515	COG1129	ABC transporter
ABO_RS09520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABO_RS09525	COG0519	Catalyzes the synthesis of GMP from XMP
ABO_RS09525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABO_RS09535	COG1570	exodeoxyribonuclease VII activity
ABO_RS09555	COG1160	GTP binding
ABO_RS09560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABO_RS09570	COG0124	histidyl-tRNA synthetase
ABO_RS09575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABO_RS09580	COG1426	Protein conserved in bacteria
ABO_RS09590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABO_RS09595	COG0105	UTP biosynthetic process
ABO_RS09600	COG0719	Fe-S assembly protein
ABO_RS09605	COG0396	ATPase activity
ABO_RS09610	COG0719	Fe-S assembly protein
ABO_RS09615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABO_RS09620	COG0316	Belongs to the HesB IscA family
ABO_RS09630	COG2166	iron-sulfur cluster assembly
ABO_RS09635	COG1104	cysteine desulfurase activity
ABO_RS09665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABO_RS09685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ABO_RS09690	COG1704	LemA family
ABO_RS09695	COG2827	Endonuclease containing a URI domain
ABO_RS09730	COG3842	ATPase activity
ABO_RS09740	COG3665	Urea carboxylase-associated protein
ABO_RS09745	COG0439	Biotin carboxylase
ABO_RS09755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABO_RS09780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABO_RS09785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABO_RS09810	COG1612	heme a metabolic process
ABO_RS09815	COG0109	protoheme IX farnesyltransferase activity
ABO_RS09825	COG1704	LemA family
ABO_RS09830	COG0501	Belongs to the peptidase M48B family
ABO_RS09845	COG1278	Cold shock
ABO_RS09850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABO_RS09890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABO_RS09895	COG3047	cAMP biosynthetic process
ABO_RS09905	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABO_RS09945	COG1999	signal sequence binding
ABO_RS09950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABO_RS09955	COG1702	phosphate starvation-inducible protein PhoH
ABO_RS09960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABO_RS09965	COG4535	Mg2 and Co2 transporter CorC
ABO_RS09980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABO_RS10000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABO_RS10000	COG3453	Protein conserved in bacteria
ABO_RS10010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ABO_RS10015	COG0495	leucyl-tRNA aminoacylation
ABO_RS10035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABO_RS10050	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABO_RS10055	COG0768	penicillin binding
ABO_RS10060	COG0772	Belongs to the SEDS family
ABO_RS10065	COG2951	lytic endotransglycosylase activity
ABO_RS10075	COG1686	Belongs to the peptidase S11 family
ABO_RS10085	COG2921	Belongs to the UPF0250 family
ABO_RS10095	COG0321	lipoyl(octanoyl) transferase activity
ABO_RS10100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABO_RS10110	COG3015	lipoprotein NlpE involved in copper resistance
ABO_RS10115	COG0811	peptide transport
ABO_RS10140	COG0163	prenyltransferase activity
ABO_RS10150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABO_RS10155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABO_RS10195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABO_RS10205	COG1131	(ABC) transporter
ABO_RS10220	COG0683	leucine binding
ABO_RS10225	COG0784	Response regulator, receiver
ABO_RS10225	COG2198	Histidine kinase
ABO_RS10225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABO_RS10225	COG2205	protein histidine kinase activity
ABO_RS10230	COG0745	RESPONSE REGULATOR receiver
ABO_RS10240	COG0205	6-phosphofructokinase activity
ABO_RS10245	COG2233	PERMEase
ABO_RS10250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABO_RS10260	COG1054	Belongs to the UPF0176 family
ABO_RS10265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABO_RS10280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABO_RS10285	COG3642	lipopolysaccharide core region biosynthetic process
ABO_RS10320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABO_RS10330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABO_RS10335	COG0511	ligase activity, forming carbon-carbon bonds
ABO_RS10345	COG2264	protein methyltransferase activity
ABO_RS10365	COG0138	bifunctional purine biosynthesis protein purh
ABO_RS10370	COG0151	Belongs to the GarS family
ABO_RS10380	COG3850	Histidine kinase
ABO_RS10380	COG2205	protein histidine kinase activity
ABO_RS10380	COG3437	response regulator, receiver
ABO_RS10380	COG4999	Histidine kinase
ABO_RS10385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABO_RS10390	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ABO_RS10395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABO_RS10400	COG1765	OsmC-like protein
ABO_RS10410	COG0134	indole-3-glycerol-phosphate synthase activity
ABO_RS10415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABO_RS10420	COG0512	Glutamine amidotransferase of anthranilate synthase
ABO_RS10445	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ABO_RS10460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABO_RS10465	COG1845	cytochrome c oxidase, subunit III
ABO_RS10470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABO_RS10475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABO_RS10480	COG0477	Major facilitator Superfamily
ABO_RS10495	COG0791	NLP P60 protein
ABO_RS10500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABO_RS10515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABO_RS10520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABO_RS10525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABO_RS10530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABO_RS10535	COG2967	ApaG domain
ABO_RS10550	COG0617	tRNA 3'-terminal CCA addition
ABO_RS10570	COG0302	gtp cyclohydrolase
ABO_RS10570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABO_RS10575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABO_RS10580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABO_RS10585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABO_RS10590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABO_RS10595	COG1610	YqeY-like protein
ABO_RS10605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABO_RS10675	COG4456	Virulence-associated protein
ABO_RS10700	COG2801	Transposase and inactivated derivatives
ABO_RS10705	COG2963	transposase activity
ABO_RS10715	COG0443	Heat shock 70 kDa protein
ABO_RS10725	COG0513	Belongs to the DEAD box helicase family
ABO_RS10750	COG4774	siderophore transport
ABO_RS10770	COG4615	Cyclic peptide transporter
ABO_RS10785	COG1960	acyl-CoA dehydrogenase activity
ABO_RS10795	COG2832	Protein of unknown function (DUF454)
ABO_RS10800	COG1960	acyl-CoA dehydrogenase activity
ABO_RS10805	COG2835	tetraacyldisaccharide 4'-kinase activity
ABO_RS10835	COG4221	oxidoreductase activity
ABO_RS10850	COG0300	oxidoreductase activity
ABO_RS10865	COG0537	adenosine 5'-monophosphoramidase activity
ABO_RS10885	COG5001	Diguanylate cyclase
ABO_RS10885	COG3706	GGDEF domain
ABO_RS10885	COG2203	Gaf domain
ABO_RS10885	COG4251	negative regulation of phosphorylation
ABO_RS10890	COG1017	nitric oxide dioxygenase activity
ABO_RS10890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABO_RS10895	COG1959	2 iron, 2 sulfur cluster binding
ABO_RS10910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABO_RS10935	COG2070	2-Nitropropane dioxygenase
ABO_RS10950	COG3437	response regulator, receiver
ABO_RS10960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABO_RS10965	COG0215	cysteine-tRNA ligase activity
ABO_RS10975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABO_RS11005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABO_RS11015	COG1469	GTP cyclohydrolase I activity
ABO_RS11025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABO_RS11030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABO_RS11035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABO_RS11055	COG0662	Cupin 2, conserved barrel domain protein
ABO_RS11070	COG2205	protein histidine kinase activity
ABO_RS11070	COG0784	Response regulator, receiver
ABO_RS11090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABO_RS11115	COG1722	exodeoxyribonuclease VII activity
ABO_RS11120	COG0142	geranyltranstransferase activity
ABO_RS11125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABO_RS11130	COG4251	negative regulation of phosphorylation
ABO_RS11130	COG5001	Diguanylate cyclase
ABO_RS11130	COG3706	GGDEF domain
ABO_RS11130	COG2203	Gaf domain
ABO_RS11135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABO_RS11140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABO_RS11145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABO_RS11150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABO_RS11165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABO_RS11165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABO_RS11170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABO_RS11175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABO_RS11180	COG0488	(ABC) transporter
ABO_RS11190	COG1595	DNA-templated transcription, initiation
ABO_RS11205	COG2226	methyltransferase
ABO_RS11210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABO_RS11225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABO_RS11230	COG0305	Participates in initiation and elongation during chromosome replication
ABO_RS11235	COG0359	binds to the 23S rRNA
ABO_RS11240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABO_RS11250	COG0360	Binds together with S18 to 16S ribosomal RNA
ABO_RS11255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABO_RS11260	COG0557	exoribonuclease II activity
ABO_RS11285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABO_RS11290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABO_RS11300	COG0330	HflC and HflK could
ABO_RS11305	COG0330	HflC and HflK could
ABO_RS11310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABO_RS11315	COG1923	regulation of RNA biosynthetic process
ABO_RS11320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABO_RS11325	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABO_RS11330	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABO_RS11335	COG0802	atpase or kinase
ABO_RS11340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABO_RS11340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABO_RS11350	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABO_RS11355	COG1162	GTPase activity
ABO_RS11365	COG0688	phosphatidylethanolamine metabolic process
ABO_RS11380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABO_RS11385	COG2226	methyltransferase
ABO_RS11390	COG2267	carboxylic ester hydrolase activity
ABO_RS11395	COG0156	8-amino-7-oxononanoate synthase activity
ABO_RS11400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABO_RS11405	COG1040	competence protein
ABO_RS11425	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABO_RS11435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABO_RS11440	COG0493	'glutamate synthase
ABO_RS11445	COG0067	glutamate synthase
ABO_RS11445	COG0070	glutamate synthase
ABO_RS11445	COG0069	glutamate synthase activity
ABO_RS11455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABO_RS11460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABO_RS11495	COG0281	malic enzyme
ABO_RS11500	COG0254	rRNA binding
ABO_RS11505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABO_RS11510	COG0018	arginyl-trna synthetase
ABO_RS11520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABO_RS11525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABO_RS11535	COG2226	methyltransferase
ABO_RS11545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABO_RS11550	COG0140	phosphoribosyl-ATP diphosphatase activity
ABO_RS11555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABO_RS11560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABO_RS11585	COG1490	D-aminoacyl-tRNA deacylase activity
ABO_RS11595	COG2204	response regulator
ABO_RS11600	COG3852	Histidine kinase
ABO_RS11620	COG0482	sulfurtransferase activity
ABO_RS11625	COG3083	sulfuric ester hydrolase activity
ABO_RS11645	COG1217	gtp-binding protein TYPA
ABO_RS11655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABO_RS11660	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ABO_RS11670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABO_RS11675	COG4942	peptidase
ABO_RS11680	COG0793	Belongs to the peptidase S41A family
ABO_RS11685	COG2861	carbohydrate metabolic process
ABO_RS11690	COG0107	imidazoleglycerol-phosphate synthase activity
ABO_RS11695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABO_RS11705	COG0131	Imidazoleglycerol-phosphate dehydratase
ABO_RS11715	COG2205	protein histidine kinase activity
ABO_RS11725	COG1194	a g-specific adenine glycosylase
ABO_RS11730	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ABO_RS11745	COG0501	Belongs to the peptidase M48B family
ABO_RS11750	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABO_RS11750	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ABO_RS11760	COG1560	Kdo2-lipid A biosynthetic process
ABO_RS11780	COG1215	transferase activity, transferring glycosyl groups
ABO_RS11790	COG0438	transferase activity, transferring glycosyl groups
ABO_RS11805	COG0859	PFAM glycosyl transferase family 9
ABO_RS11820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABO_RS11825	COG1392	Phosphate transport regulator
ABO_RS11830	COG0306	phosphate transporter
ABO_RS11835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABO_RS11835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABO_RS11880	COG2995	paraquat-inducible protein a
ABO_RS11885	COG3008	intermembrane lipid transfer
ABO_RS11885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABO_RS11900	COG2959	enzyme of heme biosynthesis
ABO_RS11910	COG0181	hydroxymethylbilane synthase activity
ABO_RS11920	COG3275	phosphorelay sensor kinase activity
ABO_RS11925	COG0165	Argininosuccinate lyase
ABO_RS11930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABO_RS11940	COG0019	diaminopimelate decarboxylase activity
ABO_RS11945	COG1757	Na H antiporter
ABO_RS11955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABO_RS11960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABO_RS11970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABO_RS11980	COG3098	single-species biofilm formation
ABO_RS12015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABO_RS12025	COG0730	response to heat
ABO_RS12040	COG0494	nUDIX hydrolase
ABO_RS12065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABO_RS12090	COG2132	Multicopper oxidase
ABO_RS12100	COG0288	reversible hydration of carbon dioxide
ABO_RS12105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABO_RS12110	COG1047	Peptidyl-prolyl cis-trans
ABO_RS12115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABO_RS12120	COG1492	cobalamin metabolic process
ABO_RS12135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ABO_RS12140	COG4139	cobalamin transport
ABO_RS12150	COG4206	TonB-dependent receptor
ABO_RS12160	COG1858	cytochrome C peroxidase
ABO_RS12175	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ABO_RS12180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABO_RS12195	COG2824	Alkylphosphonate utilization operon protein PhnA
ABO_RS12205	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABO_RS12215	COG0668	transmembrane transport
ABO_RS12220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABO_RS12240	COG0432	Pfam Uncharacterised protein family UPF0047
ABO_RS12245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABO_RS12255	COG2072	flavoprotein involved in K transport
ABO_RS12275	COG1166	arginine decarboxylase activity
ABO_RS12295	COG0583	DNA-binding transcription factor activity
ABO_RS12310	COG3008	intermembrane lipid transfer
ABO_RS12315	COG2995	paraquat-inducible protein a
ABO_RS12325	COG0513	Belongs to the DEAD box helicase family
ABO_RS12340	COG4067	protein conserved in archaea
ABO_RS12340	COG0189	ligase activity
ABO_RS12345	COG2974	May be involved in recombination
ABO_RS12350	COG0656	L-ascorbic acid biosynthetic process
ABO_RS12355	COG0596	Alpha beta hydrolase
ABO_RS12360	COG4628	conserved protein (DUF2132)
ABO_RS12370	COG1309	transcriptional regulator
ABO_RS12375	COG1979	alcohol dehydrogenase
ABO_RS12385	COG1294	oxidase, subunit
ABO_RS12390	COG1271	oxidase subunit
ABO_RS12400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABO_RS12405	COG0625	glutathione transferase activity
ABO_RS12415	COG0583	DNA-binding transcription factor activity
ABO_RS12440	COG0450	alkyl hydroperoxide reductase
ABO_RS12450	COG5001	Diguanylate cyclase
ABO_RS12450	COG3447	MASE1 domain protein
ABO_RS12450	COG5002	protein histidine kinase activity
ABO_RS12455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABO_RS12470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABO_RS12485	COG1024	Enoyl-CoA hydratase
ABO_RS12495	COG0560	Phosphoserine phosphatase
ABO_RS12495	COG3830	Belongs to the UPF0237 family
ABO_RS12500	COG3706	GGDEF domain
ABO_RS12510	COG1509	lysine 2,3-aminomutase activity
ABO_RS12515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABO_RS12520	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ABO_RS12530	COG0596	Alpha beta hydrolase
ABO_RS12540	COG0183	Belongs to the thiolase family
ABO_RS12545	COG1960	acyl-CoA dehydrogenase activity
ABO_RS12565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABO_RS12605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABO_RS12670	COG1971	Probably functions as a manganese efflux pump
ABO_RS12685	COG4771	TonB-dependent receptor
ABO_RS12690	COG0154	amidase activity
ABO_RS12695	COG0604	alcohol dehydrogenase
ABO_RS12720	COG3122	Protein conserved in bacteria
ABO_RS12735	COG0204	Acyl-transferase
ABO_RS12750	COG3150	esterase
ABO_RS12755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABO_RS12760	COG3151	Protein conserved in bacteria
ABO_RS12765	COG0494	nUDIX hydrolase
ABO_RS12770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABO_RS12775	COG1538	Outer membrane efflux protein
ABO_RS12780	COG1519	Transferase
ABO_RS12790	COG0667	Aldo Keto reductase
ABO_RS12860	COG0784	Response regulator, receiver
ABO_RS12860	COG2205	protein histidine kinase activity
ABO_RS12870	COG4566	intracellular signal transduction
ABO_RS12875	COG4191	Histidine kinase
ABO_RS12890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABO_RS12920	COG0004	ammonium transporteR
ABO_RS12925	COG0347	Belongs to the P(II) protein family
ABO_RS12930	COG2960	long-chain fatty acid transporting porin activity
ABO_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
ABO_RS12960	COG1187	pseudouridine synthase activity
ABO_RS12965	COG0210	DNA helicase
ABO_RS12995	COG2076	Multidrug Resistance protein
ABO_RS13060	COG1024	Enoyl-CoA hydratase
ABO_RS13075	COG1196	nuclear chromosome segregation
ABO_RS13075	COG3264	Mechanosensitive ion channel
ABO_RS13095	COG0742	ribosomal rna small subunit methyltransferase
ABO_RS13105	COG0612	Peptidase, M16
ABO_RS13110	COG0552	protein localization to endoplasmic reticulum
ABO_RS13115	COG2884	Cell division ATP-binding protein ftsE
ABO_RS13120	COG2177	Part of the ABC transporter FtsEX involved in
ABO_RS13130	COG2363	Small membrane protein
ABO_RS13140	COG2022	thiamine diphosphate biosynthetic process
ABO_RS13145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABO_RS13160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABO_RS13165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABO_RS13165	COG2813	Specifically methylates the guanine in position
ABO_RS13175	COG1671	Belongs to the UPF0178 family
ABO_RS13180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABO_RS13185	COG1309	transcriptional regulator
ABO_RS13195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABO_RS13220	COG1280	lysine exporter protein (LysE YggA)
ABO_RS13240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABO_RS13245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABO_RS13250	COG0509	glycine decarboxylation via glycine cleavage system
ABO_RS13255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABO_RS13265	COG1178	ABC-type Fe3 transport system permease component
ABO_RS13275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABO_RS13280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABO_RS13285	COG0006	proline dipeptidase activity
ABO_RS13290	COG3079	Belongs to the UPF0149 family
ABO_RS13305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABO_RS13310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABO_RS13315	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABO_RS13350	COG0126	phosphoglycerate kinase activity
ABO_RS13355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABO_RS13360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABO_RS13365	COG0640	Transcriptional regulator
ABO_RS13370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABO_RS13375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABO_RS13380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABO_RS13390	COG0469	pyruvate kinase activity
ABO_RS13405	COG0534	Mate efflux family protein
ABO_RS13420	COG3123	guanosine phosphorylase activity
ABO_RS13450	COG0678	peroxiredoxin activity
ABO_RS13450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABO_RS13455	COG0783	Belongs to the Dps family
ABO_RS13460	COG1272	protein, Hemolysin III
ABO_RS13465	COG0640	Transcriptional regulator
ABO_RS13480	COG0386	Belongs to the glutathione peroxidase family
ABO_RS13535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABO_RS13550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABO_RS13560	COG1320	monovalent cation:proton antiporter activity
ABO_RS13565	COG2212	antiporter activity
ABO_RS13570	COG1863	multisubunit Na H antiporter MnhE subunit
ABO_RS13575	COG0651	ATP synthesis coupled electron transport
ABO_RS13580	COG1006	Multisubunit Na H antiporter MnhC subunit
ABO_RS13585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABO_RS13585	COG2111	Na H antiporter
ABO_RS13605	COG1960	acyl-CoA dehydrogenase activity
ABO_RS13620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABO_RS13625	COG5002	protein histidine kinase activity
ABO_RS13625	COG5001	Diguanylate cyclase
ABO_RS13625	COG3447	MASE1 domain protein
ABO_RS13655	COG2900	Belongs to the SlyX family
ABO_RS13660	COG2119	membrane
ABO_RS13680	COG0431	NADPH-dependent FMN reductase
ABO_RS13685	COG0798	PFAM Bile acid sodium symporter
ABO_RS13690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABO_RS13695	COG0640	Transcriptional regulator
ABO_RS13700	COG0704	Plays a role in the regulation of phosphate uptake
ABO_RS13705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABO_RS13710	COG0581	inorganic phosphate transmembrane transporter activity
ABO_RS13715	COG0573	inorganic phosphate transmembrane transporter activity
ABO_RS13735	COG1607	acyl-coa hydrolase
ABO_RS13740	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABO_RS13745	COG0210	DNA helicase
ABO_RS13765	COG0668	transmembrane transport
ABO_RS13795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABO_RS13810	COG1793	dna ligase
ABO_RS13815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABO_RS13815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABO_RS13820	COG2354	Protein conserved in bacteria
ABO_RS13830	COG2909	trisaccharide binding
ABO_RS13835	COG3239	Fatty acid desaturase
ABO_RS13880	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABO_RS13885	COG0830	nickel cation binding
ABO_RS13895	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ABO_RS13900	COG0804	urea catabolic process
ABO_RS13905	COG0832	Belongs to the urease beta subunit family
ABO_RS13910	COG0831	urea catabolic process
ABO_RS13915	COG0829	nickel cation binding
ABO_RS13925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABO_RS13930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABO_RS13935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABO_RS13940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABO_RS13945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABO_RS13950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABO_RS13955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABO_RS13965	COG0356	it plays a direct role in the translocation of protons across the membrane
ABO_RS13975	COG1475	DNA binding
ABO_RS13980	COG1192	Involved in chromosome partitioning
ABO_RS13985	COG0357	Ribosomal RNA small subunit methyltransferase G
ABO_RS13990	COG0445	tRNA wobble uridine modification
ABO_RS14000	COG1960	acyl-CoA dehydrogenase activity
ABO_RS14015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABO_RS14020	COG0676	glucose-6-phosphate 1-epimerase activity
ABO_RS14025	COG1278	Cold shock
ABO_RS14035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABO_RS14045	COG0318	PFAM AMP-dependent synthetase and ligase
ABO_RS14055	COG1309	transcriptional regulator
ABO_RS14065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABO_RS14070	COG0706	membrane insertase activity
ABO_RS14075	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABO_RS14090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABO_RS14105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family