locus-tag	class	description
B5T_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B5T_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B5T_RS00035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B5T_RS00055	COG0683	leucine binding
B5T_RS00070	COG0751	glycine-tRNA ligase activity
B5T_RS00080	COG2818	Glycosylase
B5T_RS00085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_RS00085	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_RS00105	COG4067	protein conserved in archaea
B5T_RS00105	COG0189	ligase activity
B5T_RS00110	COG0179	Fumarylacetoacetate (FAA) hydrolase
B5T_RS00115	COG0277	FAD linked oxidase domain protein
B5T_RS00120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_RS00165	COG0405	Gamma-glutamyltransferase
B5T_RS00185	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B5T_RS00205	COG1414	Transcriptional regulator
B5T_RS00230	COG0429	hydrolase of the alpha beta-hydrolase fold
B5T_RS00235	COG0330	HflC and HflK could
B5T_RS00245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B5T_RS00250	COG0154	amidase activity
B5T_RS00255	COG0640	Transcriptional regulator
B5T_RS00270	COG2814	Major facilitator Superfamily
B5T_RS00285	COG0433	COG0433 Predicted ATPase
B5T_RS00290	COG1047	Peptidyl-prolyl cis-trans
B5T_RS00310	COG2201	protein-glutamate methylesterase activity
B5T_RS00325	COG0840	transmembrane signaling receptor activity
B5T_RS00345	COG0189	ligase activity
B5T_RS00355	COG1678	Uncharacterized ACR, COG1678
B5T_RS00360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B5T_RS00375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B5T_RS00380	COG0540	Belongs to the ATCase OTCase family
B5T_RS00395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5T_RS00405	COG0642	Histidine kinase
B5T_RS00420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5T_RS00425	COG0435	Glutathione S-transferase
B5T_RS00435	COG3093	addiction module antidote protein HigA
B5T_RS00465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_RS00495	COG1960	acyl-CoA dehydrogenase activity
B5T_RS00515	COG3239	Fatty acid desaturase
B5T_RS00520	COG0456	acetyltransferase
B5T_RS00525	COG0415	Belongs to the DNA photolyase family
B5T_RS00530	COG1024	Enoyl-CoA hydratase
B5T_RS00535	COG1960	acyl-CoA dehydrogenase activity
B5T_RS00545	COG0183	Belongs to the thiolase family
B5T_RS00560	COG3618	amidohydrolase
B5T_RS00565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5T_RS00570	COG0569	domain protein
B5T_RS00580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B5T_RS00585	COG0242	peptide deformylase activity
B5T_RS00595	COG0758	DNA mediated transformation
B5T_RS00600	COG0009	L-threonylcarbamoyladenylate synthase
B5T_RS00605	COG0408	coproporphyrinogen oxidase activity
B5T_RS00610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5T_RS00620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B5T_RS00625	COG0339	signal peptide processing
B5T_RS00650	COG3188	usher protein
B5T_RS00730	COG0583	DNA-binding transcription factor activity
B5T_RS00745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B5T_RS00750	COG0583	DNA-binding transcription factor activity
B5T_RS00760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B5T_RS00765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B5T_RS00770	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_RS00790	COG3012	SEC-C Motif Domain Protein
B5T_RS00805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_RS00815	COG3391	amine dehydrogenase activity
B5T_RS00820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B5T_RS00825	COG1758	RNA polymerase activity
B5T_RS00830	COG0194	GDP metabolic process
B5T_RS00835	COG3608	succinylglutamate desuccinylase aspartoacylase
B5T_RS00850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS00895	COG1561	YicC-like family, N-terminal region
B5T_RS00900	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B5T_RS00905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B5T_RS00915	COG1309	transcriptional regulator
B5T_RS00920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B5T_RS00930	COG0756	dUTP diphosphatase activity
B5T_RS00935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B5T_RS00940	COG2003	Belongs to the UPF0758 family
B5T_RS00945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B5T_RS00950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B5T_RS00970	COG4964	Belongs to the GSP D family
B5T_RS01015	COG1414	Transcriptional regulator
B5T_RS01025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS01030	COG0604	alcohol dehydrogenase
B5T_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS01030	COG3321	synthase
B5T_RS01065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B5T_RS01080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS01085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS01090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B5T_RS01100	COG2813	Specifically methylates the guanine in position
B5T_RS01100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_RS01105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_RS01120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B5T_RS01125	COG2022	thiamine diphosphate biosynthetic process
B5T_RS01135	COG2363	Small membrane protein
B5T_RS01145	COG2177	Part of the ABC transporter FtsEX involved in
B5T_RS01150	COG2884	Cell division ATP-binding protein ftsE
B5T_RS01155	COG0552	protein localization to endoplasmic reticulum
B5T_RS01160	COG0612	Peptidase, M16
B5T_RS01170	COG0742	ribosomal rna small subunit methyltransferase
B5T_RS01180	COG0628	permease
B5T_RS01190	COG3123	guanosine phosphorylase activity
B5T_RS01200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B5T_RS01205	COG0402	S-adenosylhomocysteine deaminase activity
B5T_RS01210	COG0534	Mate efflux family protein
B5T_RS01225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B5T_RS01230	COG0583	DNA-binding transcription factor activity
B5T_RS01240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B5T_RS01255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B5T_RS01260	COG0640	Transcriptional regulator
B5T_RS01285	COG3290	protein histidine kinase activity
B5T_RS01290	COG4565	transcriptional regulatory protein
B5T_RS01300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B5T_RS01305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B5T_RS01310	COG0126	phosphoglycerate kinase activity
B5T_RS01345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B5T_RS01380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B5T_RS01385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B5T_RS01400	COG3079	Belongs to the UPF0149 family
B5T_RS01405	COG0006	proline dipeptidase activity
B5T_RS01410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_RS01415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_RS01425	COG1178	ABC-type Fe3 transport system permease component
B5T_RS01445	COG4774	siderophore transport
B5T_RS01450	COG3712	iron ion homeostasis
B5T_RS01460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B5T_RS01465	COG0509	glycine decarboxylation via glycine cleavage system
B5T_RS01470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B5T_RS01475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B5T_RS01515	COG1063	alcohol dehydrogenase
B5T_RS01520	COG1942	4-Oxalocrotonate Tautomerase
B5T_RS01555	COG0346	lactoylglutathione lyase activity
B5T_RS01595	COG2171	N-acyltransferase activity
B5T_RS01625	COG2433	Pfam Transposase IS66
B5T_RS01655	COG1944	ATP diphosphatase activity
B5T_RS01670	COG0625	glutathione transferase activity
B5T_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS01690	COG3321	synthase
B5T_RS01690	COG0604	alcohol dehydrogenase
B5T_RS01745	COG0456	acetyltransferase
B5T_RS01750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS01755	COG0625	glutathione transferase activity
B5T_RS01805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS01810	COG1414	Transcriptional regulator
B5T_RS01815	COG1960	acyl-CoA dehydrogenase activity
B5T_RS01825	COG1652	LysM domain
B5T_RS01825	COG2823	Periplasmic or secreted lipoprotein
B5T_RS01845	COG3738	Protein conserved in bacteria
B5T_RS01855	COG0625	glutathione transferase activity
B5T_RS01895	COG0596	Alpha beta hydrolase
B5T_RS01900	COG2824	Alkylphosphonate utilization operon protein PhnA
B5T_RS01905	COG2031	fatty acid transporter
B5T_RS01915	COG0656	L-ascorbic acid biosynthetic process
B5T_RS01920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5T_RS01935	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS01975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS01980	COG0436	Aminotransferase
B5T_RS01990	COG4399	Belongs to the UPF0754 family
B5T_RS02000	COG0346	lactoylglutathione lyase activity
B5T_RS02065	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS02075	COG2974	May be involved in recombination
B5T_RS02085	COG3795	YCII-related domain
B5T_RS02090	COG4941	Belongs to the sigma-70 factor family
B5T_RS02110	COG0659	secondary active sulfate transmembrane transporter activity
B5T_RS02115	COG0730	response to heat
B5T_RS02125	COG2321	neutral zinc metallopeptidase
B5T_RS02145	COG2815	serine threonine protein kinase
B5T_RS02145	COG0515	serine threonine protein kinase
B5T_RS02150	COG2116	formate transmembrane transporter activity
B5T_RS02155	COG0586	Pfam SNARE associated Golgi protein
B5T_RS02160	COG0625	glutathione transferase activity
B5T_RS02170	COG0583	DNA-binding transcription factor activity
B5T_RS02180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B5T_RS02200	COG0513	Belongs to the DEAD box helicase family
B5T_RS02225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B5T_RS02230	COG2217	Heavy metal translocating P-type atpase
B5T_RS02250	COG1051	belongs to the nudix hydrolase family
B5T_RS02255	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B5T_RS02265	COG0730	response to heat
B5T_RS02270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B5T_RS02275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B5T_RS02325	COG0488	(ABC) transporter
B5T_RS02335	COG1742	UPF0060 membrane protein
B5T_RS02360	COG1960	acyl-CoA dehydrogenase activity
B5T_RS02375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B5T_RS02375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B5T_RS02380	COG2801	Transposase and inactivated derivatives
B5T_RS02390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_RS02395	COG0439	Biotin carboxylase
B5T_RS02405	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS02410	COG0545	Peptidyl-prolyl cis-trans isomerase
B5T_RS02420	COG1346	cytolysis
B5T_RS02430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B5T_RS02435	COG2918	glutathione biosynthetic process
B5T_RS02440	COG2183	response to ionizing radiation
B5T_RS02460	COG2814	Major facilitator Superfamily
B5T_RS02475	COG0129	dihydroxy-acid dehydratase activity
B5T_RS02485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B5T_RS02490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_RS02500	COG2133	pyrroloquinoline quinone binding
B5T_RS02505	COG0625	glutathione transferase activity
B5T_RS02525	COG1309	transcriptional regulator
B5T_RS02545	COG1595	DNA-templated transcription, initiation
B5T_RS02550	COG3712	iron ion homeostasis
B5T_RS02555	COG4771	TonB-dependent receptor
B5T_RS02565	COG2951	lytic endotransglycosylase activity
B5T_RS02575	COG1252	NADH dehydrogenase
B5T_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS02585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_RS02590	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS02610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_RS02620	COG3391	amine dehydrogenase activity
B5T_RS02660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B5T_RS02665	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B5T_RS02670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B5T_RS02675	COG1011	Hydrolase
B5T_RS02680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_RS02695	COG0494	nUDIX hydrolase
B5T_RS02700	COG1218	3'(2'),5'-bisphosphate nucleotidase
B5T_RS02735	COG5642	Protein of unknown function (DUF2384)
B5T_RS02750	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS02765	COG0747	negative chemotaxis
B5T_RS02770	COG4608	Belongs to the ABC transporter superfamily
B5T_RS02775	COG0444	Belongs to the ABC transporter superfamily
B5T_RS02790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_RS02870	COG1595	DNA-templated transcription, initiation
B5T_RS02875	COG3830	Belongs to the UPF0237 family
B5T_RS02875	COG0560	Phosphoserine phosphatase
B5T_RS02895	COG0131	Imidazoleglycerol-phosphate dehydratase
B5T_RS02900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B5T_RS02905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B5T_RS02910	COG0107	imidazoleglycerol-phosphate synthase activity
B5T_RS02915	COG1671	Belongs to the UPF0178 family
B5T_RS02930	COG0385	Bile acid
B5T_RS02935	COG2223	nitrite transmembrane transporter activity
B5T_RS02940	COG2146	nitrite reductase [NAD(P)H] activity
B5T_RS02940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS02945	COG0243	molybdopterin cofactor binding
B5T_RS02950	COG0746	molybdenum cofactor guanylyltransferase activity
B5T_RS02955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B5T_RS02965	COG0314	molybdopterin synthase activity
B5T_RS02970	COG0521	Mo-molybdopterin cofactor biosynthetic process
B5T_RS02970	COG0315	cyclic pyranopterin monophosphate synthase activity
B5T_RS02975	COG0303	'Molybdopterin
B5T_RS02980	COG0793	Belongs to the peptidase S41A family
B5T_RS02985	COG4942	peptidase
B5T_RS02990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_RS03000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B5T_RS03005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B5T_RS03015	COG1217	gtp-binding protein TYPA
B5T_RS03030	COG0189	ligase activity
B5T_RS03035	COG0482	sulfurtransferase activity
B5T_RS03045	COG0174	glutamine synthetase
B5T_RS03055	COG3852	Histidine kinase
B5T_RS03060	COG2204	response regulator
B5T_RS03070	COG1490	D-aminoacyl-tRNA deacylase activity
B5T_RS03085	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B5T_RS03085	COG3064	Membrane
B5T_RS03085	COG1073	alpha beta
B5T_RS03095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B5T_RS03100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B5T_RS03105	COG0140	phosphoribosyl-ATP diphosphatase activity
B5T_RS03110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_RS03120	COG2226	methyltransferase
B5T_RS03130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B5T_RS03130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B5T_RS03135	COG0306	phosphate transporter
B5T_RS03140	COG1392	Phosphate transport regulator
B5T_RS03145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B5T_RS03160	COG0859	PFAM glycosyl transferase family 9
B5T_RS03170	COG0859	PFAM glycosyl transferase family 9
B5T_RS03175	COG0438	transferase activity, transferring glycosyl groups
B5T_RS03185	COG0463	Glycosyl transferase, family 2
B5T_RS03195	COG0438	transferase activity, transferring glycosyl groups
B5T_RS03205	COG1560	Kdo2-lipid A biosynthetic process
B5T_RS03215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B5T_RS03215	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B5T_RS03220	COG2207	Transcriptional regulator
B5T_RS03230	COG0667	Aldo Keto reductase
B5T_RS03240	COG1519	Transferase
B5T_RS03245	COG1538	Outer membrane efflux protein
B5T_RS03250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B5T_RS03255	COG0494	nUDIX hydrolase
B5T_RS03260	COG3151	Protein conserved in bacteria
B5T_RS03265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B5T_RS03285	COG0604	alcohol dehydrogenase
B5T_RS03285	COG3321	synthase
B5T_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS03290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS03300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_RS03310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5T_RS03315	COG4566	intracellular signal transduction
B5T_RS03320	COG5507	3-demethylubiquinone-9 3-methyltransferase
B5T_RS03325	COG3150	esterase
B5T_RS03340	COG0204	Acyl-transferase
B5T_RS03350	COG3122	Protein conserved in bacteria
B5T_RS03360	COG2366	antibiotic biosynthetic process
B5T_RS03380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B5T_RS03385	COG1509	lysine 2,3-aminomutase activity
B5T_RS03415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS03440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS03445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_RS03450	COG0583	DNA-binding transcription factor activity
B5T_RS03455	COG0667	Aldo Keto reductase
B5T_RS03460	COG0583	DNA-binding transcription factor activity
B5T_RS03465	COG1024	Enoyl-CoA hydratase
B5T_RS03485	COG0473	3-isopropylmalate dehydrogenase activity
B5T_RS03490	COG2207	Transcriptional regulator
B5T_RS03495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS03510	COG3781	membrane
B5T_RS03515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B5T_RS03520	COG2375	cellular response to nickel ion
B5T_RS03530	COG3239	Fatty acid desaturase
B5T_RS03545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B5T_RS03550	COG0259	pyridoxamine-phosphate oxidase activity
B5T_RS03590	COG0410	ABC transporter
B5T_RS03605	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_RS03615	COG1802	Transcriptional regulator
B5T_RS03620	COG0439	Biotin carboxylase
B5T_RS03630	COG0583	DNA-binding transcription factor activity
B5T_RS03650	COG1079	Belongs to the binding-protein-dependent transport system permease family
B5T_RS03655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS03665	COG3845	ABC transporter
B5T_RS03670	COG1335	isochorismatase
B5T_RS03690	COG1595	DNA-templated transcription, initiation
B5T_RS03695	COG3712	iron ion homeostasis
B5T_RS03700	COG4774	siderophore transport
B5T_RS03710	COG2814	Major facilitator Superfamily
B5T_RS03715	COG1309	transcriptional regulator
B5T_RS03725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B5T_RS03730	COG1194	a g-specific adenine glycosylase
B5T_RS03745	COG0688	phosphatidylethanolamine metabolic process
B5T_RS03755	COG1162	GTPase activity
B5T_RS03760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B5T_RS03770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B5T_RS03770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B5T_RS03775	COG0802	atpase or kinase
B5T_RS03780	COG0860	N-Acetylmuramoyl-L-alanine amidase
B5T_RS03790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B5T_RS03795	COG1923	regulation of RNA biosynthetic process
B5T_RS03800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B5T_RS03805	COG0330	HflC and HflK could
B5T_RS03810	COG0330	HflC and HflK could
B5T_RS03820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B5T_RS03825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B5T_RS03840	COG1785	Belongs to the alkaline phosphatase family
B5T_RS03875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5T_RS03880	COG0360	Binds together with S18 to 16S ribosomal RNA
B5T_RS03890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B5T_RS03895	COG0359	binds to the 23S rRNA
B5T_RS03900	COG0305	Participates in initiation and elongation during chromosome replication
B5T_RS03905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B5T_RS03910	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B5T_RS03915	COG0569	domain protein
B5T_RS03920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5T_RS03945	COG2226	methyltransferase
B5T_RS03955	COG3712	iron ion homeostasis
B5T_RS03975	COG2259	Doxx family
B5T_RS03990	COG0488	(ABC) transporter
B5T_RS04000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B5T_RS04010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5T_RS04015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5T_RS04015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5T_RS04030	COG3396	Phenylacetate-CoA oxygenase
B5T_RS04035	COG3460	Phenylacetate-CoA oxygenase
B5T_RS04040	COG3396	Phenylacetate-CoA oxygenase
B5T_RS04045	COG2151	metal-sulfur cluster biosynthetic enzyme
B5T_RS04050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B5T_RS04055	COG2030	dehydratase
B5T_RS04055	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS04065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B5T_RS04080	COG0737	Belongs to the 5'-nucleotidase family
B5T_RS04090	COG0456	acetyltransferase
B5T_RS04110	COG0681	Belongs to the peptidase S26 family
B5T_RS04140	COG3327	negative regulation of DNA-templated transcription, initiation
B5T_RS04145	COG1024	Enoyl-CoA hydratase
B5T_RS04150	COG2050	protein possibly involved in aromatic compounds catabolism
B5T_RS04170	COG2197	response regulator
B5T_RS04205	COG0583	DNA-binding transcription factor activity
B5T_RS04235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B5T_RS04240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B5T_RS04245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B5T_RS04250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B5T_RS04255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B5T_RS04260	COG0142	geranyltranstransferase activity
B5T_RS04275	COG0745	RESPONSE REGULATOR receiver
B5T_RS04280	COG3539	Fimbrial protein
B5T_RS04285	COG3121	Chaperone
B5T_RS04305	COG2205	protein histidine kinase activity
B5T_RS04305	COG0784	Response regulator, receiver
B5T_RS04315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_RS04335	COG5002	protein histidine kinase activity
B5T_RS04345	COG0662	Cupin 2, conserved barrel domain protein
B5T_RS04350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B5T_RS04360	COG1846	Transcriptional regulator
B5T_RS04365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_RS04375	COG1469	GTP cyclohydrolase I activity
B5T_RS04405	COG0215	cysteine-tRNA ligase activity
B5T_RS04410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B5T_RS04420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B5T_RS04420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B5T_RS04445	COG0537	adenosine 5'-monophosphoramidase activity
B5T_RS04470	COG1307	EDD domain protein, DegV family
B5T_RS04490	COG0300	oxidoreductase activity
B5T_RS04535	COG2835	tetraacyldisaccharide 4'-kinase activity
B5T_RS04540	COG1960	acyl-CoA dehydrogenase activity
B5T_RS04545	COG2832	Protein of unknown function (DUF454)
B5T_RS04550	COG1960	acyl-CoA dehydrogenase activity
B5T_RS04600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_RS04630	COG2771	luxR family
B5T_RS04635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5T_RS04645	COG2771	luxR family
B5T_RS04725	COG2354	Protein conserved in bacteria
B5T_RS04735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B5T_RS04750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B5T_RS04755	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B5T_RS04760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B5T_RS04765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B5T_RS04785	COG0617	tRNA 3'-terminal CCA addition
B5T_RS04795	COG2719	SpoVR family
B5T_RS04800	COG2718	Belongs to the UPF0229 family
B5T_RS04805	COG2766	serine protein kinase
B5T_RS04815	COG2967	ApaG domain
B5T_RS04820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B5T_RS04825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B5T_RS04830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_RS04835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B5T_RS04850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B5T_RS04860	COG0791	NLP P60 protein
B5T_RS04875	COG0477	Major facilitator Superfamily
B5T_RS04880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B5T_RS04885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B5T_RS04890	COG1845	cytochrome c oxidase, subunit III
B5T_RS04895	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B5T_RS04910	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B5T_RS04915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B5T_RS04920	COG0512	Glutamine amidotransferase of anthranilate synthase
B5T_RS04925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B5T_RS04930	COG0134	indole-3-glycerol-phosphate synthase activity
B5T_RS04940	COG1765	OsmC-like protein
B5T_RS04945	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B5T_RS04950	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B5T_RS04955	COG0784	Response regulator, receiver
B5T_RS04955	COG2205	protein histidine kinase activity
B5T_RS04955	COG5002	protein histidine kinase activity
B5T_RS04960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS04965	COG0730	response to heat
B5T_RS04970	COG0151	Belongs to the GarS family
B5T_RS04975	COG0138	bifunctional purine biosynthesis protein purh
B5T_RS04980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B5T_RS04995	COG2264	protein methyltransferase activity
B5T_RS05015	COG0511	ligase activity, forming carbon-carbon bonds
B5T_RS05020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B5T_RS05045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B5T_RS05050	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B5T_RS05075	COG0747	negative chemotaxis
B5T_RS05085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5T_RS05100	COG2267	carboxylic ester hydrolase activity
B5T_RS05105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B5T_RS05145	COG0205	6-phosphofructokinase activity
B5T_RS05155	COG0745	RESPONSE REGULATOR receiver
B5T_RS05160	COG0784	Response regulator, receiver
B5T_RS05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5T_RS05160	COG2198	Histidine kinase
B5T_RS05160	COG2205	protein histidine kinase activity
B5T_RS05190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS05215	COG4774	siderophore transport
B5T_RS05220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B5T_RS05225	COG0163	prenyltransferase activity
B5T_RS05230	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B5T_RS05245	COG0811	peptide transport
B5T_RS05250	COG3015	lipoprotein NlpE involved in copper resistance
B5T_RS05270	COG2807	transmembrane transport
B5T_RS05275	COG1846	Transcriptional regulator
B5T_RS05280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B5T_RS05285	COG0321	lipoyl(octanoyl) transferase activity
B5T_RS05300	COG1686	Belongs to the peptidase S11 family
B5T_RS05310	COG2951	lytic endotransglycosylase activity
B5T_RS05315	COG0772	Belongs to the SEDS family
B5T_RS05320	COG0768	penicillin binding
B5T_RS05325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B5T_RS05335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B5T_RS05340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B5T_RS05360	COG0495	leucyl-tRNA aminoacylation
B5T_RS05370	COG0471	metal ion transport
B5T_RS05375	COG0659	secondary active sulfate transmembrane transporter activity
B5T_RS05380	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5T_RS05395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B5T_RS05400	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B5T_RS05405	COG4535	Mg2 and Co2 transporter CorC
B5T_RS05410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B5T_RS05415	COG1702	phosphate starvation-inducible protein PhoH
B5T_RS05420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B5T_RS05425	COG4208	sulfate ABC transporter
B5T_RS05435	COG4150	thiosulfate binding
B5T_RS05440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B5T_RS05445	COG1999	signal sequence binding
B5T_RS05485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B5T_RS05500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_RS05530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_RS05535	COG1278	Cold shock
B5T_RS05550	COG0501	Belongs to the peptidase M48B family
B5T_RS05555	COG1704	LemA family
B5T_RS05560	COG0109	protoheme IX farnesyltransferase activity
B5T_RS05565	COG1612	heme a metabolic process
B5T_RS05595	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B5T_RS05600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B5T_RS05605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B5T_RS05665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B5T_RS05670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS05675	COG1022	Amp-dependent synthetase and ligase
B5T_RS05710	COG3284	Transcriptional regulator
B5T_RS05725	COG0439	Biotin carboxylase
B5T_RS05740	COG1116	anion transmembrane transporter activity
B5T_RS05745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS05770	COG2827	Endonuclease containing a URI domain
B5T_RS05780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B5T_RS05815	COG1104	cysteine desulfurase activity
B5T_RS05825	COG2166	iron-sulfur cluster assembly
B5T_RS05830	COG2151	metal-sulfur cluster biosynthetic enzyme
B5T_RS05835	COG0316	Belongs to the HesB IscA family
B5T_RS05840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B5T_RS05845	COG0719	Fe-S assembly protein
B5T_RS05850	COG0396	ATPase activity
B5T_RS05855	COG0719	Fe-S assembly protein
B5T_RS05860	COG0105	UTP biosynthetic process
B5T_RS05865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B5T_RS05875	COG1426	Protein conserved in bacteria
B5T_RS05880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B5T_RS05885	COG0124	histidyl-tRNA synthetase
B5T_RS05900	COG1160	GTP binding
B5T_RS05915	COG5002	protein histidine kinase activity
B5T_RS05915	COG2205	protein histidine kinase activity
B5T_RS05915	COG0784	Response regulator, receiver
B5T_RS05920	COG1570	exodeoxyribonuclease VII activity
B5T_RS05930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_RS05930	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_RS05945	COG5290	Psort location Cytoplasmic, score
B5T_RS05950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_RS05950	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_RS05970	COG0494	nUDIX hydrolase
B5T_RS05975	COG2205	protein histidine kinase activity
B5T_RS05980	COG0745	RESPONSE REGULATOR receiver
B5T_RS05990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS06000	COG1595	DNA-templated transcription, initiation
B5T_RS06005	COG3712	iron ion homeostasis
B5T_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS06020	COG1733	regulation of RNA biosynthetic process
B5T_RS06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
B5T_RS06055	COG1309	transcriptional regulator
B5T_RS06090	COG3609	addiction module antidote protein, CC2985 family
B5T_RS06105	COG2433	Pfam Transposase IS66
B5T_RS06125	COG0556	nucleotide-excision repair
B5T_RS06130	COG0326	Molecular chaperone. Has ATPase activity
B5T_RS06150	COG1304	FMN binding
B5T_RS06160	COG1595	DNA-templated transcription, initiation
B5T_RS06165	COG3712	iron ion homeostasis
B5T_RS06190	COG0583	DNA-binding transcription factor activity
B5T_RS06195	COG1335	isochorismatase
B5T_RS06205	COG1335	isochorismatase
B5T_RS06215	COG0667	Aldo Keto reductase
B5T_RS06250	COG0024	Methionine aminopeptidase
B5T_RS06270	COG2814	Major facilitator Superfamily
B5T_RS06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5T_RS06310	COG0251	oxidation-reduction process
B5T_RS06330	COG0662	Cupin 2, conserved barrel domain protein
B5T_RS06330	COG2207	Transcriptional regulator
B5T_RS06345	COG3457	Alanine racemase
B5T_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS06355	COG2207	Transcriptional regulator
B5T_RS06370	COG2207	Transcriptional regulator
B5T_RS06390	COG3541	Predicted nucleotidyltransferase
B5T_RS06395	COG4774	siderophore transport
B5T_RS06425	COG0693	protein deglycase activity
B5T_RS06430	COG4638	Rieske (2fe-2S)
B5T_RS06440	COG0667	Aldo Keto reductase
B5T_RS06505	COG2226	methyltransferase
B5T_RS06510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5T_RS06530	COG4993	Dehydrogenase
B5T_RS06535	COG0477	Major facilitator Superfamily
B5T_RS06545	COG0583	DNA-binding transcription factor activity
B5T_RS06550	COG1960	acyl-CoA dehydrogenase activity
B5T_RS06555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS06560	COG3795	YCII-related domain
B5T_RS06575	COG0477	Major facilitator Superfamily
B5T_RS06585	COG0583	DNA-binding transcription factor activity
B5T_RS06610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B5T_RS06620	COG2910	NAD(P)H-binding
B5T_RS06645	COG0251	oxidation-reduction process
B5T_RS06650	COG3181	Tripartite tricarboxylate transporter family receptor
B5T_RS06655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B5T_RS06675	COG3971	2-oxopent-4-enoate hydratase activity
B5T_RS06695	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS06720	COG1595	DNA-templated transcription, initiation
B5T_RS06765	COG0848	biopolymer transport protein
B5T_RS06775	COG4558	Periplasmic binding protein
B5T_RS06780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5T_RS06785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B5T_RS06795	COG1121	(ABC) transporter
B5T_RS06800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_RS06805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_RS06820	COG1024	Enoyl-CoA hydratase
B5T_RS06825	COG0183	Belongs to the thiolase family
B5T_RS06840	COG1309	transcriptional regulator
B5T_RS06865	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B5T_RS06875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B5T_RS06890	COG3323	Protein of unknown function (DUF1653)
B5T_RS06890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B5T_RS06895	COG2816	NAD+ diphosphatase activity
B5T_RS06900	COG0494	nUDIX hydrolase
B5T_RS06915	COG1752	Esterase of the alpha-beta hydrolase superfamily
B5T_RS06925	COG2801	Transposase and inactivated derivatives
B5T_RS06930	COG4536	flavin adenine dinucleotide binding
B5T_RS06940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B5T_RS06945	COG0228	four-way junction DNA binding
B5T_RS06950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B5T_RS06955	COG0336	Belongs to the RNA methyltransferase TrmD family
B5T_RS06960	COG0335	large ribosomal subunit rRNA binding
B5T_RS06980	COG0436	Aminotransferase
B5T_RS06990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B5T_RS07000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B5T_RS07015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS07020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5T_RS07025	COG2264	protein methyltransferase activity
B5T_RS07055	COG4953	penicillin-binding protein 1C
B5T_RS07080	COG0488	(ABC) transporter
B5T_RS07090	COG1196	nuclear chromosome segregation
B5T_RS07090	COG3264	Mechanosensitive ion channel
B5T_RS07105	COG0709	Synthesizes selenophosphate from selenide and ATP
B5T_RS07110	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B5T_RS07120	COG1309	transcriptional regulator
B5T_RS07145	COG3030	protein affecting phage T7 exclusion by the F plasmid
B5T_RS07155	COG0183	Belongs to the thiolase family
B5T_RS07160	COG1946	Acyl-CoA thioesterase
B5T_RS07190	COG1902	pentaerythritol trinitrate reductase activity
B5T_RS07190	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5T_RS07195	COG1960	acyl-CoA dehydrogenase activity
B5T_RS07200	COG1960	acyl-CoA dehydrogenase activity
B5T_RS07220	COG1115	amino acid carrier protein
B5T_RS07250	COG3360	Dodecin
B5T_RS07285	COG4771	TonB-dependent receptor
B5T_RS07295	COG0175	sulfate reduction
B5T_RS07305	COG2267	carboxylic ester hydrolase activity
B5T_RS07330	COG1063	alcohol dehydrogenase
B5T_RS07350	COG0583	DNA-binding transcription factor activity
B5T_RS07365	COG4774	siderophore transport
B5T_RS07380	COG0488	(ABC) transporter
B5T_RS07425	COG0183	Belongs to the thiolase family
B5T_RS07430	COG1024	Enoyl-CoA hydratase
B5T_RS07430	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_RS07435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B5T_RS07450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B5T_RS07460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B5T_RS07465	COG1024	Enoyl-CoA hydratase
B5T_RS07470	COG2070	2-Nitropropane dioxygenase
B5T_RS07515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5T_RS07520	COG0481	GTPase activity
B5T_RS07535	COG0571	ribonuclease III activity
B5T_RS07545	COG1381	Involved in DNA repair and RecF pathway recombination
B5T_RS07550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B5T_RS07555	COG5002	protein histidine kinase activity
B5T_RS07555	COG0784	Response regulator, receiver
B5T_RS07555	COG2205	protein histidine kinase activity
B5T_RS07570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B5T_RS07575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B5T_RS07580	COG3956	TIGRFAM MazG family protein
B5T_RS07600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B5T_RS07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5T_RS07615	COG3088	subunit of a heme lyase
B5T_RS07625	COG0563	adenylate kinase activity
B5T_RS07645	COG3630	sodium ion export across plasma membrane
B5T_RS07650	COG0511	ligase activity, forming carbon-carbon bonds
B5T_RS07650	COG5016	pyruvate
B5T_RS07655	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B5T_RS07665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS07665	COG1116	anion transmembrane transporter activity
B5T_RS07670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS07675	COG1116	anion transmembrane transporter activity
B5T_RS07680	COG3707	response regulator
B5T_RS07685	COG1116	anion transmembrane transporter activity
B5T_RS07685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS07690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B5T_RS07695	COG0583	DNA-binding transcription factor activity
B5T_RS07705	COG2954	triphosphatase activity
B5T_RS07710	COG4133	protoheme IX ABC transporter activity
B5T_RS07730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B5T_RS07740	COG0189	ligase activity
B5T_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS07810	COG1131	(ABC) transporter
B5T_RS07815	COG0842	Transport permease protein
B5T_RS07820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B5T_RS07820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B5T_RS07825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B5T_RS07835	COG0778	Nitroreductase
B5T_RS07885	COG0583	DNA-binding transcription factor activity
B5T_RS07890	COG0596	Alpha beta hydrolase
B5T_RS07930	COG0183	Belongs to the thiolase family
B5T_RS07935	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS07945	COG1960	acyl-CoA dehydrogenase activity
B5T_RS07950	COG1960	acyl-CoA dehydrogenase activity
B5T_RS07960	COG1024	Enoyl-CoA hydratase
B5T_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS08000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS08005	COG3829	transcription factor binding
B5T_RS08045	COG2205	protein histidine kinase activity
B5T_RS08045	COG0784	Response regulator, receiver
B5T_RS08075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_RS08100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS08105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS08110	COG1309	transcriptional regulator
B5T_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS08130	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS08135	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_RS08160	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_RS08160	COG1024	Enoyl-CoA hydratase
B5T_RS08165	COG1960	acyl-CoA dehydrogenase activity
B5T_RS08170	COG1960	acyl-CoA dehydrogenase activity
B5T_RS08175	COG2130	NADP-dependent
B5T_RS08185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5T_RS08190	COG0280	phosphate acetyltransferase
B5T_RS08190	COG0281	malic enzyme
B5T_RS08195	COG0235	Class ii aldolase
B5T_RS08230	COG2030	dehydratase
B5T_RS08235	COG1960	acyl-CoA dehydrogenase activity
B5T_RS08240	COG1024	Enoyl-CoA hydratase
B5T_RS08245	COG1960	acyl-CoA dehydrogenase activity
B5T_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS08255	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS08280	COG0183	Belongs to the thiolase family
B5T_RS08285	COG1846	Transcriptional regulator
B5T_RS08290	COG1764	response to oxidative stress
B5T_RS08320	COG1739	Uncharacterized protein family UPF0029
B5T_RS08345	COG3206	protein involved in exopolysaccharide biosynthesis
B5T_RS08345	COG0489	protein tyrosine kinase activity
B5T_RS08350	COG0471	metal ion transport
B5T_RS08350	COG3273	potassium ion transport
B5T_RS08355	COG0529	Catalyzes the synthesis of activated sulfate
B5T_RS08360	COG0250	Participates in transcription elongation, termination and antitermination
B5T_RS08365	COG3609	addiction module antidote protein, CC2985 family
B5T_RS08385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B5T_RS08430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5T_RS08445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B5T_RS08470	COG2433	Pfam Transposase IS66
B5T_RS08490	COG3549	Plasmid maintenance system killer
B5T_RS08495	COG3093	addiction module antidote protein HigA
B5T_RS08510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_RS08520	COG0183	Belongs to the thiolase family
B5T_RS08525	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS08530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B5T_RS08560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B5T_RS08570	COG0166	Belongs to the GPI family
B5T_RS08595	COG1215	transferase activity, transferring glycosyl groups
B5T_RS08630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5T_RS08640	COG0436	Aminotransferase
B5T_RS08675	COG3791	Glutathione-dependent formaldehyde-activating
B5T_RS08690	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_RS08700	COG3115	cell septum assembly
B5T_RS08705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B5T_RS08720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5T_RS08720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B5T_RS08735	COG2205	protein histidine kinase activity
B5T_RS08735	COG5002	protein histidine kinase activity
B5T_RS08735	COG0784	Response regulator, receiver
B5T_RS08745	COG4106	trans-aconitate 2-methyltransferase activity
B5T_RS08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_RS08780	COG0583	DNA-binding transcription factor activity
B5T_RS08785	COG3527	Alpha-acetolactate decarboxylase
B5T_RS08800	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS08810	COG1024	Enoyl-CoA hydratase
B5T_RS08815	COG1960	acyl-CoA dehydrogenase activity
B5T_RS08820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_RS08825	COG4221	oxidoreductase activity
B5T_RS08860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS08865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B5T_RS08875	COG0308	aminopeptidase N
B5T_RS08890	COG3130	regulation of translation
B5T_RS08895	COG0116	Belongs to the methyltransferase superfamily
B5T_RS08895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B5T_RS08905	COG0084	hydrolase, TatD family'
B5T_RS08915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B5T_RS08925	COG0589	response to stress
B5T_RS08945	COG1309	transcriptional regulator
B5T_RS08950	COG1376	ErfK ybiS ycfS ynhG family protein
B5T_RS08960	COG0668	transmembrane transport
B5T_RS08965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B5T_RS09010	COG2081	HI0933 family
B5T_RS09015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B5T_RS09020	COG1946	Acyl-CoA thioesterase
B5T_RS09030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B5T_RS09035	COG1805	sodium ion transport
B5T_RS09050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B5T_RS09055	COG2871	sodium ion transport
B5T_RS09060	COG1477	protein flavinylation
B5T_RS09065	COG2991	Protein conserved in bacteria
B5T_RS09080	COG0584	glycerophosphoryl diester phosphodiesterase
B5T_RS09110	COG0583	DNA-binding transcription factor activity
B5T_RS09125	COG0625	glutathione transferase activity
B5T_RS09140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS09145	COG2957	Belongs to the agmatine deiminase family
B5T_RS09160	COG1136	(ABC) transporter
B5T_RS09165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B5T_RS09175	COG0714	Associated with various cellular activities
B5T_RS09210	COG1393	Belongs to the ArsC family
B5T_RS09215	COG1295	ribonuclease BN
B5T_RS09215	COG1959	2 iron, 2 sulfur cluster binding
B5T_RS09220	COG1254	Belongs to the acylphosphatase family
B5T_RS09235	COG0657	acetylesterase activity
B5T_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS09300	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B5T_RS09305	COG2894	cell division
B5T_RS09310	COG0850	regulation of cytokinetic process
B5T_RS09315	COG2026	Addiction module toxin, RelE StbE family
B5T_RS09330	COG3550	peptidyl-serine autophosphorylation
B5T_RS09345	COG3118	belongs to the thioredoxin family
B5T_RS09350	COG0004	ammonium transporteR
B5T_RS09355	COG2326	polyphosphate kinase activity
B5T_RS09365	COG1199	ATP-dependent helicase activity
B5T_RS09380	COG1968	undecaprenyl-diphosphatase activity
B5T_RS09385	COG0742	ribosomal rna small subunit methyltransferase
B5T_RS09390	COG2937	Belongs to the GPAT DAPAT family
B5T_RS09410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5T_RS09420	COG1393	Belongs to the ArsC family
B5T_RS09425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_RS09430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B5T_RS09435	COG0024	Methionine aminopeptidase
B5T_RS09440	COG0052	Belongs to the universal ribosomal protein uS2 family
B5T_RS09445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B5T_RS09450	COG0528	UMP kinase activity
B5T_RS09455	COG0233	cytoplasmic translational termination
B5T_RS09460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B5T_RS09465	COG0575	Belongs to the CDS family
B5T_RS09470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B5T_RS09490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_RS09495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B5T_RS09505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_RS09510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B5T_RS09515	COG0587	DNA-directed DNA polymerase activity
B5T_RS09520	COG0825	malonyl-CoA metabolic process
B5T_RS09525	COG0037	tRNA processing
B5T_RS09530	COG0504	CTP synthase activity
B5T_RS09535	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B5T_RS09540	COG0148	phosphopyruvate hydratase activity
B5T_RS09545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B5T_RS09555	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B5T_RS09560	COG0585	pseudouridine synthase activity
B5T_RS09565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B5T_RS09600	COG3001	Fructosamine kinase
B5T_RS09605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_RS09615	COG0300	oxidoreductase activity
B5T_RS09620	COG0037	tRNA processing
B5T_RS09625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B5T_RS09630	COG0583	DNA-binding transcription factor activity
B5T_RS09635	COG2814	Major facilitator Superfamily
B5T_RS09640	COG0667	Aldo Keto reductase
B5T_RS09660	COG0667	Aldo Keto reductase
B5T_RS09675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B5T_RS09690	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
B5T_RS09695	COG2153	protein acetylation
B5T_RS09700	COG2850	peptidyl-arginine hydroxylation
B5T_RS09710	COG2915	High frequency lysogenization protein hflD homolog
B5T_RS09715	COG0482	sulfurtransferase activity
B5T_RS09735	COG1278	Cold shock
B5T_RS09740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B5T_RS09745	COG0542	response to heat
B5T_RS09750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B5T_RS09755	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B5T_RS09760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_RS09765	COG4774	siderophore transport
B5T_RS09770	COG3712	iron ion homeostasis
B5T_RS09775	COG1595	DNA-templated transcription, initiation
B5T_RS09780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B5T_RS09785	COG0492	ferredoxin-NADP+ reductase activity
B5T_RS09790	COG1674	ftsk spoiiie
B5T_RS09795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B5T_RS09800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B5T_RS09805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B5T_RS09810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B5T_RS09815	COG1648	precorrin-2 dehydrogenase activity
B5T_RS09815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B5T_RS09820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B5T_RS09835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B5T_RS09860	COG2274	protein secretion by the type I secretion system
B5T_RS09865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS09875	COG0477	Major facilitator Superfamily
B5T_RS09890	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS09915	COG1960	acyl-CoA dehydrogenase activity
B5T_RS09920	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
B5T_RS09935	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS09950	COG1960	acyl-CoA dehydrogenase activity
B5T_RS09955	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS09960	COG1802	Transcriptional regulator
B5T_RS09970	COG1280	lysine exporter protein (LysE YggA)
B5T_RS09975	COG0003	Pfam Anion-transporting ATPase
B5T_RS09985	COG1966	Carbon starvation protein
B5T_RS09990	COG2197	response regulator
B5T_RS09995	COG0322	excinuclease ABC activity
B5T_RS10000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B5T_RS10055	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS10060	COG1960	acyl-CoA dehydrogenase activity
B5T_RS10115	COG1021	2,3-dihydroxybenzoate-AMP ligase
B5T_RS10120	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS10140	COG2030	dehydratase
B5T_RS10145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5T_RS10170	COG0657	acetylesterase activity
B5T_RS10190	COG0633	Ferredoxin
B5T_RS10210	COG1309	transcriptional regulator
B5T_RS10215	COG2801	Transposase and inactivated derivatives
B5T_RS10225	COG2801	Transposase and inactivated derivatives
B5T_RS10265	COG3209	COG3209 Rhs family protein
B5T_RS10350	COG1074	ATP-dependent DNA helicase activity
B5T_RS10520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B5T_RS10605	COG1192	Involved in chromosome partitioning
B5T_RS10610	COG5295	Hep Hag repeat protein
B5T_RS10630	COG1414	Transcriptional regulator
B5T_RS10635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B5T_RS10660	COG0683	leucine binding
B5T_RS10695	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B5T_RS10700	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS10710	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS10870	COG0784	Response regulator, receiver
B5T_RS10870	COG2205	protein histidine kinase activity
B5T_RS10875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B5T_RS10890	COG3437	response regulator, receiver
B5T_RS10950	COG0646	methionine synthase
B5T_RS10950	COG1410	methionine synthase
B5T_RS10965	COG2813	Specifically methylates the guanine in position
B5T_RS10970	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
B5T_RS10975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B5T_RS10980	COG0235	Class ii aldolase
B5T_RS10985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B5T_RS11025	COG0560	Phosphoserine phosphatase
B5T_RS11045	COG0616	signal peptide processing
B5T_RS11050	COG0604	alcohol dehydrogenase
B5T_RS11065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS11075	COG0534	Mate efflux family protein
B5T_RS11080	COG0316	Belongs to the HesB IscA family
B5T_RS11080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B5T_RS11085	COG0501	Belongs to the peptidase M48B family
B5T_RS11090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_RS11105	COG0564	pseudouridine synthase activity
B5T_RS11110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_RS11130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B5T_RS11170	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_RS11185	COG0700	Nucleoside recognition
B5T_RS11195	COG0598	Magnesium transport protein CorA
B5T_RS11200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_RS11210	COG3022	response to hydroperoxide
B5T_RS11215	COG0589	response to stress
B5T_RS11220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS11250	COG0348	domain, Protein
B5T_RS11255	COG2010	Cytochrome c
B5T_RS11270	COG3278	Belongs to the heme-copper respiratory oxidase family
B5T_RS11275	COG4774	siderophore transport
B5T_RS11280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS11290	COG1846	Transcriptional regulator
B5T_RS11310	COG1335	isochorismatase
B5T_RS11315	COG3473	Maleate cis-trans isomerase
B5T_RS11320	COG0596	Alpha beta hydrolase
B5T_RS11325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_RS11330	COG2309	aminopeptidase activity
B5T_RS11335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B5T_RS11335	COG2010	Cytochrome c
B5T_RS11340	COG2080	2 iron, 2 sulfur cluster binding
B5T_RS11345	COG2010	Cytochrome c
B5T_RS11345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B5T_RS11355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_RS11380	COG0583	DNA-binding transcription factor activity
B5T_RS11385	COG0583	DNA-binding transcription factor activity
B5T_RS11390	COG2814	Major facilitator Superfamily
B5T_RS11405	COG0330	HflC and HflK could
B5T_RS11410	COG0697	spore germination
B5T_RS11435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B5T_RS11445	COG0180	Tryptophanyl-tRNA synthetase
B5T_RS11450	COG0009	L-threonylcarbamoyladenylate synthase
B5T_RS11455	COG0613	PHP domain protein
B5T_RS11460	COG2917	probably involved in intracellular septation
B5T_RS11465	COG2350	Protein conserved in bacteria
B5T_RS11480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS11485	COG0204	Acyl-transferase
B5T_RS11505	COG4181	ATPase activity
B5T_RS11515	COG2814	Major facilitator Superfamily
B5T_RS11530	COG1070	Carbohydrate kinase
B5T_RS11535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B5T_RS11540	COG0277	FAD linked oxidase domain protein
B5T_RS11545	COG2885	chlorophyll binding
B5T_RS11570	COG3243	poly(R)-hydroxyalkanoic acid synthase
B5T_RS11575	COG3339	Conserved Protein
B5T_RS11580	COG1192	Involved in chromosome partitioning
B5T_RS11595	COG0069	glutamate synthase activity
B5T_RS11600	COG0739	heme binding
B5T_RS11600	COG1196	nuclear chromosome segregation
B5T_RS11600	COG0741	lytic transglycosylase activity
B5T_RS11615	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B5T_RS11625	COG2079	MmgE PrpD family protein
B5T_RS11635	COG2852	Protein conserved in bacteria
B5T_RS11645	COG0372	Belongs to the citrate synthase family
B5T_RS11650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B5T_RS11655	COG1802	Transcriptional regulator
B5T_RS11675	COG0328	RNA-DNA hybrid ribonuclease activity
B5T_RS11685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_RS11690	COG1388	LysM domain
B5T_RS11690	COG0741	lytic transglycosylase activity
B5T_RS11695	COG4166	transmembrane transport
B5T_RS11700	COG4174	ABC transporter (Permease)
B5T_RS11705	COG4239	(ABC) transporter, permease
B5T_RS11710	COG4172	Belongs to the ABC transporter superfamily
B5T_RS11720	COG0737	Belongs to the 5'-nucleotidase family
B5T_RS11725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_RS11740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_RS11745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B5T_RS11750	COG0740	serine-type endopeptidase activity
B5T_RS11755	COG0544	peptidyl-prolyl cis-trans isomerase activity
B5T_RS11775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B5T_RS11790	COG1289	transmembrane transporter activity
B5T_RS11795	COG3422	double-strand break repair
B5T_RS11800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_RS11815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_RS11830	COG1309	transcriptional regulator
B5T_RS11840	COG2814	Major facilitator Superfamily
B5T_RS11850	COG2814	Major facilitator Superfamily
B5T_RS11870	COG3119	arylsulfatase activity
B5T_RS11915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B5T_RS11950	COG1643	Atp-dependent helicase
B5T_RS11965	COG0625	glutathione transferase activity
B5T_RS11970	COG0583	DNA-binding transcription factor activity
B5T_RS11990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B5T_RS12005	COG1054	Belongs to the UPF0176 family
B5T_RS12010	COG0271	Belongs to the BolA IbaG family
B5T_RS12025	COG0039	L-malate dehydrogenase activity
B5T_RS12030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B5T_RS12035	COG0702	epimerase
B5T_RS12050	COG1960	acyl-CoA dehydrogenase activity
B5T_RS12055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_RS12060	COG1024	Enoyl-CoA hydratase
B5T_RS12070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_RS12080	COG0824	Thioesterase
B5T_RS12115	COG0587	DNA-directed DNA polymerase activity
B5T_RS12130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_RS12140	COG0589	response to stress
B5T_RS12145	COG0659	secondary active sulfate transmembrane transporter activity
B5T_RS12160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5T_RS12165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B5T_RS12185	COG3220	belongs to the UPF0276 family
B5T_RS12195	COG1309	transcriptional regulator
B5T_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS12215	COG1960	acyl-CoA dehydrogenase activity
B5T_RS12220	COG1024	Enoyl-CoA hydratase
B5T_RS12225	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS12270	COG1643	Atp-dependent helicase
B5T_RS12285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B5T_RS12310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_RS12320	COG2271	Major facilitator Superfamily
B5T_RS12330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B5T_RS12340	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B5T_RS12350	COG2205	protein histidine kinase activity
B5T_RS12380	COG1021	2,3-dihydroxybenzoate-AMP ligase
B5T_RS12405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_RS12405	COG3321	synthase
B5T_RS12405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B5T_RS12405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5T_RS12410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5T_RS12415	COG1132	(ABC) transporter
B5T_RS12420	COG2375	cellular response to nickel ion
B5T_RS12420	COG1132	(ABC) transporter
B5T_RS12425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_RS12425	COG2226	methyltransferase
B5T_RS12425	COG3433	isochorismatase activity
B5T_RS12430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_RS12440	COG1131	(ABC) transporter
B5T_RS12450	COG4771	TonB-dependent receptor
B5T_RS12455	COG4771	TonB-dependent receptor
B5T_RS12475	COG2311	Membrane
B5T_RS12495	COG4771	TonB-dependent receptor
B5T_RS12500	COG1429	ligase activity, forming nitrogen-metal bonds
B5T_RS12520	COG2356	endonuclease I
B5T_RS12525	COG1802	Transcriptional regulator
B5T_RS12545	COG2801	Transposase and inactivated derivatives
B5T_RS12585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5T_RS12600	COG0535	radical SAM domain protein
B5T_RS12615	COG0625	glutathione transferase activity
B5T_RS12645	COG5002	protein histidine kinase activity
B5T_RS12705	COG2186	Transcriptional regulator
B5T_RS12710	COG1620	l-lactate permease
B5T_RS12715	COG0247	lactate metabolic process
B5T_RS12770	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
B5T_RS12840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_RS12855	COG4574	serine-type endopeptidase inhibitor activity
B5T_RS12875	COG2433	Pfam Transposase IS66
B5T_RS12900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B5T_RS12910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B5T_RS12915	COG3622	Belongs to the hyi family
B5T_RS12920	COG0672	)-iron permease
B5T_RS12930	COG0436	Aminotransferase
B5T_RS12940	COG0501	Belongs to the peptidase M48B family
B5T_RS12970	COG0714	Associated with various cellular activities
B5T_RS12985	COG1286	toxin biosynthetic process
B5T_RS12995	COG0285	dihydrofolate synthase activity
B5T_RS13000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B5T_RS13005	COG0159	tryptophan synthase activity
B5T_RS13015	COG0135	phosphoribosylanthranilate isomerase activity
B5T_RS13020	COG0101	tRNA pseudouridine synthase activity
B5T_RS13030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B5T_RS13040	COG0473	3-isopropylmalate dehydrogenase activity
B5T_RS13045	COG0066	3-isopropylmalate dehydratase activity
B5T_RS13050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B5T_RS13060	COG2801	Transposase and inactivated derivatives
B5T_RS13070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B5T_RS13090	COG1301	dicarboxylic acid transport
B5T_RS13105	COG3268	Saccharopine dehydrogenase
B5T_RS13115	COG3712	iron ion homeostasis
B5T_RS13145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B5T_RS13150	COG1522	sequence-specific DNA binding
B5T_RS13155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_RS13165	COG0708	Exodeoxyribonuclease III
B5T_RS13180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B5T_RS13185	COG0326	Molecular chaperone. Has ATPase activity
B5T_RS13190	COG1090	epimerase
B5T_RS13215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5T_RS13230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B5T_RS13240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B5T_RS13245	COG0045	succinate-CoA ligase (ADP-forming) activity
B5T_RS13270	COG1053	succinate dehydrogenase
B5T_RS13275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B5T_RS13305	COG2084	Dehydrogenase
B5T_RS13325	COG0579	oxidoreductase
B5T_RS13335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS13350	COG1305	Transglutaminase-like
B5T_RS13360	COG2308	Evidence 4 Homologs of previously reported genes of
B5T_RS13380	COG0583	DNA-binding transcription factor activity
B5T_RS13385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS13385	COG3153	acetyltransferase
B5T_RS13410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS13415	COG2146	nitrite reductase [NAD(P)H] activity
B5T_RS13420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS13420	COG2146	nitrite reductase [NAD(P)H] activity
B5T_RS13435	COG1104	cysteine desulfurase activity
B5T_RS13450	COG1322	Protein conserved in bacteria
B5T_RS13455	COG0084	hydrolase, TatD family'
B5T_RS13470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B5T_RS13475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B5T_RS13480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B5T_RS13485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B5T_RS13490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5T_RS13505	COG0416	fatty acid biosynthetic process
B5T_RS13510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B5T_RS13520	COG0424	maF-like protein
B5T_RS13530	COG0546	phosphoglycolate phosphatase activity
B5T_RS13535	COG0564	pseudouridine synthase activity
B5T_RS13540	COG1530	ribonuclease E activity
B5T_RS13550	COG4804	nuclease activity
B5T_RS13555	COG2003	Belongs to the UPF0758 family
B5T_RS13595	COG5489	Protein of unknown function (DUF736)
B5T_RS13625	COG1192	Involved in chromosome partitioning
B5T_RS13650	COG0583	DNA-binding transcription factor activity
B5T_RS13655	COG3384	dioxygenase
B5T_RS13660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5T_RS13675	COG2207	Transcriptional regulator
B5T_RS13680	COG0667	Aldo Keto reductase
B5T_RS13690	COG4584	PFAM Integrase catalytic
B5T_RS13695	COG1484	DNA-dependent DNA replication
B5T_RS13700	COG2378	regulation of single-species biofilm formation
B5T_RS13710	COG0583	DNA-binding transcription factor activity
B5T_RS13755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B5T_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS13780	COG0300	oxidoreductase activity
B5T_RS13790	COG0583	DNA-binding transcription factor activity
B5T_RS13810	COG4962	Type ii secretion system protein e
B5T_RS13815	COG3838	Conjugal transfer protein Trbc
B5T_RS13825	COG3451	type IV secretory pathway VirB4
B5T_RS13840	COG3846	protein secretion by the type IV secretion system
B5T_RS13855	COG2948	multi-organism process
B5T_RS13865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B5T_RS13870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5T_RS13875	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B5T_RS13880	COG1663	tetraacyldisaccharide 4'-kinase activity
B5T_RS13885	COG1132	(ABC) transporter
B5T_RS13890	COG0848	biopolymer transport protein
B5T_RS13895	COG0811	peptide transport
B5T_RS13900	COG2333	competence protein COMEC
B5T_RS13900	COG0658	competence protein
B5T_RS13910	COG3101	peptidyl-lysine hydroxylation
B5T_RS13960	COG2223	nitrite transmembrane transporter activity
B5T_RS13965	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B5T_RS13970	COG0788	formyltetrahydrofolate deformylase activity
B5T_RS13975	COG2207	Transcriptional regulator
B5T_RS13990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS13995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS14000	COG1116	anion transmembrane transporter activity
B5T_RS14015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS14020	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B5T_RS14025	COG4771	TonB-dependent receptor
B5T_RS14035	COG0314	molybdopterin synthase activity
B5T_RS14045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B5T_RS14070	COG1024	Enoyl-CoA hydratase
B5T_RS14080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS14090	COG0028	Belongs to the TPP enzyme family
B5T_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS14100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS14110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_RS14115	COG1304	FMN binding
B5T_RS14130	COG4948	Mandelate Racemase Muconate Lactonizing
B5T_RS14135	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS14145	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS14150	COG0583	DNA-binding transcription factor activity
B5T_RS14155	COG0163	prenyltransferase activity
B5T_RS14210	COG4774	siderophore transport
B5T_RS14215	COG3712	iron ion homeostasis
B5T_RS14240	COG1024	Enoyl-CoA hydratase
B5T_RS14250	COG1960	acyl-CoA dehydrogenase activity
B5T_RS14270	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS14280	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS14300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_RS14325	COG2144	transferase activity, transferring acyl groups
B5T_RS14340	COG2193	ferroxidase activity
B5T_RS14345	COG1024	Enoyl-CoA hydratase
B5T_RS14345	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_RS14350	COG0183	Belongs to the thiolase family
B5T_RS14360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B5T_RS14370	COG2840	Smr protein MutS2
B5T_RS14375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B5T_RS14380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B5T_RS14390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B5T_RS14395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B5T_RS14410	COG0717	Belongs to the dCTP deaminase family
B5T_RS14415	COG0489	protein tyrosine kinase activity
B5T_RS14430	COG0450	alkyl hydroperoxide reductase
B5T_RS14435	COG0583	DNA-binding transcription factor activity
B5T_RS14440	COG1064	alcohol dehydrogenase
B5T_RS14470	COG3042	response to heat
B5T_RS14490	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B5T_RS14510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B5T_RS14520	COG3383	formate dehydrogenase (NAD+) activity
B5T_RS14535	COG2005	Transcriptional regulator
B5T_RS14535	COG3585	molybdate ion transport
B5T_RS14540	COG2223	nitrite transmembrane transporter activity
B5T_RS14545	COG1793	dna ligase
B5T_RS14550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5T_RS14555	COG2813	Specifically methylates the guanine in position
B5T_RS14560	COG0741	lytic transglycosylase activity
B5T_RS14565	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B5T_RS14605	COG5002	protein histidine kinase activity
B5T_RS14605	COG2205	protein histidine kinase activity
B5T_RS14605	COG0784	Response regulator, receiver
B5T_RS14610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5T_RS14610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5T_RS14620	COG4657	Part of a membrane complex involved in electron transport
B5T_RS14625	COG2878	Part of a membrane complex involved in electron transport
B5T_RS14630	COG4656	Part of a membrane complex involved in electron transport
B5T_RS14635	COG4658	electron transport chain
B5T_RS14640	COG4659	FMN binding
B5T_RS14645	COG4660	Part of a membrane complex involved in electron transport
B5T_RS14655	COG0786	glutamate:sodium symporter activity
B5T_RS14660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B5T_RS14665	COG1555	photosystem II stabilization
B5T_RS14665	COG1596	polysaccharide export
B5T_RS14670	COG0284	orotidine-5'-phosphate decarboxylase activity
B5T_RS14675	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B5T_RS14685	COG0776	regulation of translation
B5T_RS14695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B5T_RS14700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B5T_RS14705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_RS14710	COG0077	Prephenate dehydratase
B5T_RS14710	COG1605	Chorismate mutase
B5T_RS14715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B5T_RS14725	COG0402	S-adenosylhomocysteine deaminase activity
B5T_RS14730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_RS14735	COG0546	phosphoglycolate phosphatase activity
B5T_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS14785	COG2226	methyltransferase
B5T_RS14800	COG2983	Belongs to the UPF0260 family
B5T_RS14805	COG3100	YcgL domain-containing protein
B5T_RS14810	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B5T_RS14815	COG0588	phosphoglycerate mutase activity
B5T_RS14820	COG5380	lipid catabolic process
B5T_RS14825	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B5T_RS14835	COG1960	acyl-CoA dehydrogenase activity
B5T_RS14840	COG1454	alcohol dehydrogenase
B5T_RS14845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B5T_RS14850	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B5T_RS14885	COG1695	Transcriptional regulator
B5T_RS14905	COG0427	acetyl-CoA hydrolase
B5T_RS14920	COG1136	(ABC) transporter
B5T_RS14935	COG0418	dihydroorotase activity
B5T_RS14960	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS14975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B5T_RS14980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_RS14995	COG1609	Transcriptional regulator
B5T_RS15005	COG0583	DNA-binding transcription factor activity
B5T_RS15010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B5T_RS15015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS15035	COG2070	2-Nitropropane dioxygenase
B5T_RS15040	COG3189	MarR family transcriptional regulator
B5T_RS15050	COG1294	oxidase, subunit
B5T_RS15060	COG4988	ABC transporter
B5T_RS15065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B5T_RS15070	COG0826	peptidase U32
B5T_RS15075	COG0826	peptidase U32
B5T_RS15090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B5T_RS15095	COG3154	lipid carrier protein
B5T_RS15100	COG2223	nitrite transmembrane transporter activity
B5T_RS15105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B5T_RS15110	COG1140	nitrate reductase beta subunit
B5T_RS15115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B5T_RS15120	COG2181	nitrate reductase activity
B5T_RS15140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_RS15150	COG3094	Invasion gene expression up-regulator, SirB
B5T_RS15155	COG1959	2 iron, 2 sulfur cluster binding
B5T_RS15160	COG1959	2 iron, 2 sulfur cluster binding
B5T_RS15180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B5T_RS15185	COG0840	transmembrane signaling receptor activity
B5T_RS15235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_RS15245	COG2851	Citrate transporter
B5T_RS15255	COG0066	3-isopropylmalate dehydratase activity
B5T_RS15260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B5T_RS15270	COG3180	Ammonia monooxygenase
B5T_RS15280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B5T_RS15285	COG0527	aspartate kinase activity
B5T_RS15290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B5T_RS15305	COG2137	regulation of response to DNA damage stimulus
B5T_RS15315	COG1546	Belongs to the CinA family
B5T_RS15355	COG3586	endonuclease activity
B5T_RS15360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B5T_RS15385	COG0732	type I restriction modification DNA specificity domain
B5T_RS15390	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
B5T_RS15435	COG4771	TonB-dependent receptor
B5T_RS15445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B5T_RS15450	COG1309	transcriptional regulator
B5T_RS15465	COG1024	Enoyl-CoA hydratase
B5T_RS15475	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS15480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B5T_RS15485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B5T_RS15530	COG1509	lysine 2,3-aminomutase activity
B5T_RS15535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_RS15545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B5T_RS15550	COG1074	ATP-dependent DNA helicase activity
B5T_RS15555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_RS15565	COG3784	Protein of unknown function (DUF1318)
B5T_RS15670	COG2433	Pfam Transposase IS66
B5T_RS15725	COG2003	Belongs to the UPF0758 family
B5T_RS15805	COG0776	regulation of translation
B5T_RS15815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B5T_RS15820	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B5T_RS15825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B5T_RS15830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B5T_RS15835	COG2814	Major facilitator Superfamily
B5T_RS15840	COG0583	DNA-binding transcription factor activity
B5T_RS15865	COG1271	oxidase subunit
B5T_RS15870	COG1294	oxidase, subunit
B5T_RS15875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B5T_RS15880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5T_RS15890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B5T_RS15900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_RS15910	COG0425	Belongs to the sulfur carrier protein TusA family
B5T_RS15930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B5T_RS15935	COG0602	queuosine metabolic process
B5T_RS15950	COG0823	Involved in the tonB-independent uptake of proteins
B5T_RS15970	COG0824	Thioesterase
B5T_RS15975	COG2255	four-way junction helicase activity
B5T_RS15980	COG0632	four-way junction helicase activity
B5T_RS15985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B5T_RS15990	COG0217	transcriptional regulatory protein
B5T_RS15995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B5T_RS16015	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B5T_RS16020	COG0729	surface antigen
B5T_RS16035	COG0442	prolyl-tRNA aminoacylation
B5T_RS16045	COG1192	Involved in chromosome partitioning
B5T_RS16050	COG1960	acyl-CoA dehydrogenase activity
B5T_RS16055	COG1309	transcriptional regulator
B5T_RS16070	COG0514	ATP-dependent DNA helicase (RecQ)
B5T_RS16080	COG0513	Belongs to the DEAD box helicase family
B5T_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS16120	COG0189	ligase activity
B5T_RS16125	COG4067	protein conserved in archaea
B5T_RS16125	COG0189	ligase activity
B5T_RS16130	COG0137	argininosuccinate synthase activity
B5T_RS16135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B5T_RS16140	COG0450	alkyl hydroperoxide reductase
B5T_RS16160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B5T_RS16165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B5T_RS16170	COG3842	ATPase activity
B5T_RS16185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B5T_RS16190	COG2205	protein histidine kinase activity
B5T_RS16195	COG0745	RESPONSE REGULATOR receiver
B5T_RS16200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5T_RS16200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5T_RS16205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5T_RS16280	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS16285	COG3384	dioxygenase
B5T_RS16295	COG3971	2-oxopent-4-enoate hydratase activity
B5T_RS16305	COG1846	Transcriptional regulator
B5T_RS16310	COG0683	leucine binding
B5T_RS16315	COG0861	Integral membrane protein TerC family
B5T_RS16330	COG0601	transmembrane transport
B5T_RS16335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5T_RS16340	COG0444	Belongs to the ABC transporter superfamily
B5T_RS16345	COG4608	Belongs to the ABC transporter superfamily
B5T_RS16350	COG0747	negative chemotaxis
B5T_RS16380	COG0655	NAD(P)H dehydrogenase (quinone) activity
B5T_RS16390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS16390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B5T_RS16410	COG0705	Rhomboid family
B5T_RS16420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B5T_RS16435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS16440	COG0402	S-adenosylhomocysteine deaminase activity
B5T_RS16450	COG1335	isochorismatase
B5T_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS16465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B5T_RS16470	COG1116	anion transmembrane transporter activity
B5T_RS16495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B5T_RS16515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B5T_RS16520	COG1611	Belongs to the LOG family
B5T_RS16535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B5T_RS16540	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B5T_RS16570	COG0735	belongs to the Fur family
B5T_RS16575	COG0523	cobalamin synthesis protein
B5T_RS16580	COG1960	acyl-CoA dehydrogenase activity
B5T_RS16585	COG0583	DNA-binding transcription factor activity
B5T_RS16590	COG2814	Major facilitator Superfamily
B5T_RS16600	COG2249	NAD(P)H dehydrogenase (quinone) activity
B5T_RS16605	COG0583	DNA-binding transcription factor activity
B5T_RS16670	COG0183	Belongs to the thiolase family
B5T_RS16680	COG4993	Dehydrogenase
B5T_RS16715	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS16725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B5T_RS16730	COG1191	sigma factor activity
B5T_RS16750	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B5T_RS16765	COG0745	RESPONSE REGULATOR receiver
B5T_RS16770	COG0840	transmembrane signaling receptor activity
B5T_RS16775	COG2201	protein-glutamate methylesterase activity
B5T_RS16780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B5T_RS16785	COG0840	transmembrane signaling receptor activity
B5T_RS16795	COG0835	chemotaxis
B5T_RS16800	COG0643	Histidine kinase
B5T_RS16800	COG2198	Histidine kinase
B5T_RS16805	COG1360	Flagellar Motor Protein
B5T_RS16845	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B5T_RS16870	COG1677	Flagellar hook-basal body complex protein FliE
B5T_RS16905	COG1580	Controls the rotational direction of flagella during chemotaxis
B5T_RS16930	COG1987	bacterial-type flagellum assembly
B5T_RS16940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B5T_RS16945	COG1256	bacterial-type flagellum assembly
B5T_RS16955	COG1706	bacterial-type flagellum-dependent cell motility
B5T_RS16985	COG1558	bacterial-type flagellum-dependent cell motility
B5T_RS17010	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B5T_RS17030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_RS17055	COG0459	protein refolding
B5T_RS17060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B5T_RS17070	COG2211	Major facilitator Superfamily
B5T_RS17075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5T_RS17080	COG2096	Adenosyltransferase
B5T_RS17085	COG2205	protein histidine kinase activity
B5T_RS17090	COG0745	RESPONSE REGULATOR receiver
B5T_RS17125	COG1115	amino acid carrier protein
B5T_RS17140	COG2358	TRAP transporter, solute receptor (TAXI family
B5T_RS17165	COG4969	Belongs to the N-Me-Phe pilin family
B5T_RS17180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B5T_RS17185	COG0237	dephospho-CoA kinase activity
B5T_RS17190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B5T_RS17200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B5T_RS17205	COG0653	protein targeting
B5T_RS17210	COG0739	heme binding
B5T_RS17220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B5T_RS17235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B5T_RS17240	COG1181	Belongs to the D-alanine--D-alanine ligase family
B5T_RS17245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B5T_RS17250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B5T_RS17255	COG0772	Belongs to the SEDS family
B5T_RS17260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B5T_RS17265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B5T_RS17270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5T_RS17275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B5T_RS17290	COG0275	rRNA processing
B5T_RS17295	COG2001	Belongs to the MraZ family
B5T_RS17305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B5T_RS17315	COG0792	nuclease activity
B5T_RS17360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B5T_RS17360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS17365	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS17380	COG3119	arylsulfatase activity
B5T_RS17385	COG2969	positive regulation of protein catabolic process
B5T_RS17390	COG0625	glutathione transferase activity
B5T_RS17395	COG2857	Cytochrome c1
B5T_RS17400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B5T_RS17405	COG0723	plastoquinol--plastocyanin reductase activity
B5T_RS17410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B5T_RS17415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B5T_RS17420	COG0667	Aldo Keto reductase
B5T_RS17425	COG1309	transcriptional regulator
B5T_RS17440	COG1802	Transcriptional regulator
B5T_RS17470	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS17475	COG1960	acyl-CoA dehydrogenase activity
B5T_RS17535	COG3657	addiction module killer protein
B5T_RS17540	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_RS17555	COG2067	long-chain fatty acid transport protein
B5T_RS17560	COG1960	acyl-CoA dehydrogenase activity
B5T_RS17565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B5T_RS17570	COG2945	thiolester hydrolase activity
B5T_RS17580	COG2046	Belongs to the sulfate adenylyltransferase family
B5T_RS17585	COG1597	lipid kinase activity
B5T_RS17595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5T_RS17605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_RS17610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B5T_RS17615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B5T_RS17620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B5T_RS17625	COG5007	Belongs to the BolA IbaG family
B5T_RS17645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B5T_RS17660	COG1137	ATPase activity
B5T_RS17665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B5T_RS17680	COG1660	Displays ATPase and GTPase activities
B5T_RS17695	COG0443	Heat shock 70 kDa protein
B5T_RS17705	COG0312	modulator of DNA gyrase
B5T_RS17710	COG3028	Belongs to the UPF0307 family
B5T_RS17715	COG2807	transmembrane transport
B5T_RS17720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_RS17720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5T_RS17725	COG0312	modulator of DNA gyrase
B5T_RS17730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_RS17740	COG0424	maF-like protein
B5T_RS17745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B5T_RS17750	COG1792	Involved in formation and maintenance of cell shape
B5T_RS17755	COG1077	Cell shape determining protein MreB Mrl
B5T_RS17760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5T_RS17765	COG0154	amidase activity
B5T_RS17770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5T_RS17785	COG1024	Enoyl-CoA hydratase
B5T_RS17855	COG3038	cytochrome b561
B5T_RS17870	COG2205	protein histidine kinase activity
B5T_RS17875	COG2197	response regulator
B5T_RS17890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B5T_RS17895	COG2890	protein-(glutamine-N5) methyltransferase activity
B5T_RS17900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B5T_RS17905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B5T_RS17915	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B5T_RS17920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B5T_RS17930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B5T_RS17935	COG2801	Transposase and inactivated derivatives
B5T_RS17945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B5T_RS17950	COG0193	aminoacyl-tRNA hydrolase activity
B5T_RS17960	COG0012	GTP binding
B5T_RS17970	COG2068	MobA-Related Protein
B5T_RS17975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B5T_RS18030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_RS18050	COG0697	spore germination
B5T_RS18060	COG0438	transferase activity, transferring glycosyl groups
B5T_RS18075	COG0438	transferase activity, transferring glycosyl groups
B5T_RS18090	COG3436	PFAM IS66 Orf2 family protein
B5T_RS18100	COG1045	serine acetyltransferase
B5T_RS18105	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B5T_RS18115	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS18120	COG0473	3-isopropylmalate dehydrogenase activity
B5T_RS18125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B5T_RS18135	COG0154	amidase activity
B5T_RS18140	COG0436	Aminotransferase
B5T_RS18150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B5T_RS18155	COG1862	Preprotein translocase
B5T_RS18160	COG0343	queuine tRNA-ribosyltransferase activity
B5T_RS18165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B5T_RS18190	COG0795	lipopolysaccharide-transporting ATPase activity
B5T_RS18195	COG0795	lipopolysaccharide-transporting ATPase activity
B5T_RS18200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B5T_RS18210	COG0525	valine-tRNA ligase activity
B5T_RS18225	COG1597	lipid kinase activity
B5T_RS18245	COG2433	Pfam Transposase IS66
B5T_RS18265	COG1183	phosphatidylcholine synthase activity
B5T_RS18270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B5T_RS18285	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS18300	COG0028	Belongs to the TPP enzyme family
B5T_RS18395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B5T_RS18400	COG1047	Peptidyl-prolyl cis-trans
B5T_RS18405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B5T_RS18410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B5T_RS18415	COG0196	riboflavin kinase activity
B5T_RS18420	COG0728	peptidoglycan biosynthetic process
B5T_RS18425	COG0268	Binds directly to 16S ribosomal RNA
B5T_RS18430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B5T_RS18435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B5T_RS18440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B5T_RS18445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B5T_RS18450	COG0142	geranyltranstransferase activity
B5T_RS18485	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS18520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_RS18535	COG4221	oxidoreductase activity
B5T_RS18540	COG2267	carboxylic ester hydrolase activity
B5T_RS18595	COG2814	Major facilitator Superfamily
B5T_RS18630	COG0659	secondary active sulfate transmembrane transporter activity
B5T_RS18640	COG0203	ribosomal protein L17
B5T_RS18645	COG0202	RNA polymerase activity
B5T_RS18650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B5T_RS18655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B5T_RS18660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B5T_RS18665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B5T_RS18675	COG0200	Binds to the 23S rRNA
B5T_RS18680	COG1841	ribosomal large subunit assembly
B5T_RS18685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B5T_RS18690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B5T_RS18695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B5T_RS18700	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B5T_RS18705	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B5T_RS18710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B5T_RS18715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B5T_RS18720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B5T_RS18725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B5T_RS18730	COG0255	Belongs to the universal ribosomal protein uL29 family
B5T_RS18735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B5T_RS18740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B5T_RS18745	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B5T_RS18750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B5T_RS18755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B5T_RS18760	COG0089	rRNA binding
B5T_RS18765	COG0088	Forms part of the polypeptide exit tunnel
B5T_RS18770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B5T_RS18775	COG0051	transcription antitermination factor activity, RNA binding
B5T_RS18780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B5T_RS18785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B5T_RS18790	COG0049	tRNA binding
B5T_RS18795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B5T_RS18800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B5T_RS18805	COG0085	RNA polymerase activity
B5T_RS18810	COG0222	ribosome binding
B5T_RS18815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B5T_RS18820	COG0081	regulation of translation
B5T_RS18825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B5T_RS18845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B5T_RS18875	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B5T_RS18900	COG2433	Pfam Transposase IS66
B5T_RS18930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B5T_RS18935	COG0739	heme binding
B5T_RS18940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B5T_RS18950	COG0316	Belongs to the HesB IscA family
B5T_RS18970	COG1981	membrane
B5T_RS18975	COG0351	phosphomethylpyrimidine kinase
B5T_RS18975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B5T_RS18975	COG0352	thiamine-phosphate diphosphorylase activity
B5T_RS18980	COG0352	thiamine-phosphate diphosphorylase activity
B5T_RS18985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B5T_RS19000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5T_RS19005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B5T_RS19015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B5T_RS19020	COG1489	DNA binding
B5T_RS19025	COG0436	Aminotransferase
B5T_RS19035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B5T_RS19040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_RS19060	COG0617	tRNA 3'-terminal CCA addition
B5T_RS19070	COG1428	Deoxynucleoside kinase
B5T_RS19075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B5T_RS19080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B5T_RS19085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B5T_RS19090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_RS19100	COG2814	Major facilitator Superfamily
B5T_RS19115	COG2056	Na+-H+ antiporter family
B5T_RS19120	COG1185	polyribonucleotide nucleotidyltransferase activity
B5T_RS19125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B5T_RS19135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B5T_RS19140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B5T_RS19145	COG2251	uridine kinase activity
B5T_RS19145	COG0195	Participates in both transcription termination and antitermination
B5T_RS19150	COG0779	Required for maturation of 30S ribosomal subunits
B5T_RS19170	COG0149	triose-phosphate isomerase activity
B5T_RS19175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5T_RS19180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B5T_RS19185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B5T_RS19190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B5T_RS19205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B5T_RS19210	COG0505	Belongs to the CarA family
B5T_RS19215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B5T_RS19220	COG0484	heat shock protein binding
B5T_RS19225	COG0443	Heat shock 70 kDa protein
B5T_RS19230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B5T_RS19235	COG1420	regulation of RNA biosynthetic process
B5T_RS19240	COG0497	DNA recombination
B5T_RS19255	COG2914	Belongs to the UPF0125 (RnfH) family
B5T_RS19260	COG0733	neurotransmitter:sodium symporter activity
B5T_RS19265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B5T_RS19285	COG0667	Aldo Keto reductase
B5T_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS19295	COG0583	DNA-binding transcription factor activity
B5T_RS19325	COG0154	amidase activity
B5T_RS19355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS19390	COG2807	transmembrane transport
B5T_RS19405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS19410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
B5T_RS19425	COG3648	Uricase
B5T_RS19425	COG3195	allantoin biosynthetic process
B5T_RS19445	COG4266	Belongs to the allantoicase family
B5T_RS19450	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B5T_RS19465	COG0583	DNA-binding transcription factor activity
B5T_RS19480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS19490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS19495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS19505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_RS19515	COG3964	amidohydrolase
B5T_RS19525	COG1414	Transcriptional regulator
B5T_RS19545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5T_RS19555	COG0505	Belongs to the CarA family
B5T_RS19565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_RS19570	COG1522	sequence-specific DNA binding
B5T_RS19575	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS19580	COG1309	transcriptional regulator
B5T_RS19600	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS19605	COG1024	Enoyl-CoA hydratase
B5T_RS19630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B5T_RS19635	COG2226	methyltransferase
B5T_RS19640	COG0596	Alpha beta hydrolase
B5T_RS19645	COG0156	8-amino-7-oxononanoate synthase activity
B5T_RS19650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B5T_RS19660	COG2045	Belongs to the ComB family
B5T_RS19670	COG2154	pterin-4-alpha-carbinolamine dehydratase
B5T_RS19680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B5T_RS19685	COG0493	'glutamate synthase
B5T_RS19690	COG0069	glutamate synthase activity
B5T_RS19690	COG0067	glutamate synthase
B5T_RS19690	COG0070	glutamate synthase
B5T_RS19700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B5T_RS19705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B5T_RS19765	COG1137	ATPase activity
B5T_RS19790	COG0281	malic enzyme
B5T_RS19795	COG0254	rRNA binding
B5T_RS19800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B5T_RS19805	COG0477	Major facilitator Superfamily
B5T_RS19810	COG1566	PFAM secretion protein HlyD family protein
B5T_RS19815	COG0018	arginyl-trna synthetase
B5T_RS19825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B5T_RS19830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B5T_RS19835	COG0129	dihydroxy-acid dehydratase activity
B5T_RS19845	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS19850	COG1454	alcohol dehydrogenase
B5T_RS19865	COG0543	2 iron, 2 sulfur cluster binding
B5T_RS19865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B5T_RS19870	COG2995	paraquat-inducible protein a
B5T_RS19875	COG3008	intermembrane lipid transfer
B5T_RS19875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B5T_RS19900	COG0181	hydroxymethylbilane synthase activity
B5T_RS19910	COG3275	phosphorelay sensor kinase activity
B5T_RS19915	COG0165	Argininosuccinate lyase
B5T_RS19930	COG4774	siderophore transport
B5T_RS19940	COG1595	DNA-templated transcription, initiation
B5T_RS19965	COG3712	iron ion homeostasis
B5T_RS19970	COG1595	DNA-templated transcription, initiation
B5T_RS19975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B5T_RS19980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_RS19990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B5T_RS19995	COG2267	carboxylic ester hydrolase activity
B5T_RS20010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B5T_RS20020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B5T_RS20030	COG3098	single-species biofilm formation
B5T_RS20035	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B5T_RS20045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_RS20060	COG0248	Ppx GppA phosphatase
B5T_RS20075	COG1335	isochorismatase
B5T_RS20080	COG0583	DNA-binding transcription factor activity
B5T_RS20090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B5T_RS20120	COG2205	protein histidine kinase activity
B5T_RS20125	COG0745	RESPONSE REGULATOR receiver
B5T_RS20130	COG3268	Saccharopine dehydrogenase
B5T_RS20140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B5T_RS20140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS20150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_RS20155	COG2186	Transcriptional regulator
B5T_RS20160	COG0154	amidase activity
B5T_RS20165	COG0604	alcohol dehydrogenase
B5T_RS20170	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20185	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B5T_RS20210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B5T_RS20215	COG1595	DNA-templated transcription, initiation
B5T_RS20245	COG3530	Putative quorum-sensing-regulated virulence factor
B5T_RS20260	COG0789	Transcriptional regulator
B5T_RS20265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B5T_RS20270	COG3384	dioxygenase
B5T_RS20280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B5T_RS20295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_RS20320	COG2169	Transcriptional regulator
B5T_RS20320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B5T_RS20350	COG3634	alkyl hydroperoxide reductase activity
B5T_RS20365	COG0840	transmembrane signaling receptor activity
B5T_RS20375	COG2132	Multicopper oxidase
B5T_RS20385	COG0288	reversible hydration of carbon dioxide
B5T_RS20390	COG1047	Peptidyl-prolyl cis-trans
B5T_RS20395	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20420	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20430	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS20435	COG1960	acyl-CoA dehydrogenase activity
B5T_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS20450	COG2030	dehydratase
B5T_RS20460	COG4191	Histidine kinase
B5T_RS20465	COG4566	intracellular signal transduction
B5T_RS20475	COG0489	protein tyrosine kinase activity
B5T_RS20485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_RS20495	COG2188	Transcriptional regulator
B5T_RS20515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B5T_RS20535	COG1959	2 iron, 2 sulfur cluster binding
B5T_RS20540	COG1492	cobalamin metabolic process
B5T_RS20555	COG1120	ATPase activity
B5T_RS20560	COG4139	cobalamin transport
B5T_RS20565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B5T_RS20570	COG4206	TonB-dependent receptor
B5T_RS20595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B5T_RS20600	COG3642	lipopolysaccharide core region biosynthetic process
B5T_RS20610	COG0642	Histidine kinase
B5T_RS20650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS20660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_RS20675	COG0432	Pfam Uncharacterised protein family UPF0047
B5T_RS20680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B5T_RS20695	COG1166	arginine decarboxylase activity
B5T_RS20710	COG4221	oxidoreductase activity
B5T_RS20740	COG1566	PFAM secretion protein HlyD family protein
B5T_RS20760	COG5002	protein histidine kinase activity
B5T_RS20775	COG0004	ammonium transporteR
B5T_RS20780	COG0347	Belongs to the P(II) protein family
B5T_RS20785	COG2960	long-chain fatty acid transporting porin activity
B5T_RS20790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
B5T_RS20800	COG0606	chelatase, subunit chli
B5T_RS20805	COG0697	spore germination
B5T_RS20815	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS20825	COG1187	pseudouridine synthase activity
B5T_RS20840	COG5002	protein histidine kinase activity
B5T_RS20850	COG0745	RESPONSE REGULATOR receiver
B5T_RS20870	COG1960	acyl-CoA dehydrogenase activity
B5T_RS20875	COG1960	acyl-CoA dehydrogenase activity
B5T_RS20890	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20895	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20910	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS20915	COG0183	Belongs to the thiolase family
B5T_RS20925	COG2909	trisaccharide binding
B5T_RS20935	COG1024	Enoyl-CoA hydratase
B5T_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS20945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_RS20955	COG1024	Enoyl-CoA hydratase
B5T_RS20960	COG1960	acyl-CoA dehydrogenase activity
B5T_RS20975	COG1024	Enoyl-CoA hydratase
B5T_RS20985	COG1024	Enoyl-CoA hydratase
B5T_RS21000	COG1280	lysine exporter protein (LysE YggA)
B5T_RS21010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_RS21020	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS21045	COG1515	deoxyribonuclease V activity
B5T_RS21085	COG1566	PFAM secretion protein HlyD family protein
B5T_RS21100	COG2353	YceI-like domain
B5T_RS21105	COG3038	cytochrome b561
B5T_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS21120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5T_RS21125	COG0385	Bile acid
B5T_RS21130	COG0492	ferredoxin-NADP+ reductase activity
B5T_RS21145	COG1024	Enoyl-CoA hydratase
B5T_RS21160	COG0517	IMP dehydrogenase activity
B5T_RS21160	COG1125	glycine betaine transport
B5T_RS21190	COG0678	peroxiredoxin activity
B5T_RS21190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B5T_RS21205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS21215	COG0753	catalase activity
B5T_RS21220	COG1272	protein, Hemolysin III
B5T_RS21230	COG0386	Belongs to the glutathione peroxidase family
B5T_RS21260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B5T_RS21305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B5T_RS21310	COG1320	monovalent cation:proton antiporter activity
B5T_RS21315	COG2212	antiporter activity
B5T_RS21320	COG1863	multisubunit Na H antiporter MnhE subunit
B5T_RS21325	COG0651	ATP synthesis coupled electron transport
B5T_RS21330	COG1006	Multisubunit Na H antiporter MnhC subunit
B5T_RS21335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B5T_RS21335	COG2111	Na H antiporter
B5T_RS21350	COG1160	GTP binding
B5T_RS21365	COG1960	acyl-CoA dehydrogenase activity
B5T_RS21370	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_RS21370	COG1024	Enoyl-CoA hydratase
B5T_RS21380	COG5285	phytanoyl-CoA dioxygenase
B5T_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_RS21430	COG1131	(ABC) transporter
B5T_RS21435	COG0842	Transport permease protein
B5T_RS21455	COG0625	glutathione transferase activity
B5T_RS21460	COG0668	transmembrane transport
B5T_RS21465	COG0678	peroxiredoxin activity
B5T_RS21480	COG1666	GTP binding
B5T_RS21490	COG3093	addiction module antidote protein HigA
B5T_RS21495	COG1901	pseudouridine methyltransferase
B5T_RS21500	COG0500	methyltransferase
B5T_RS21510	COG0657	acetylesterase activity
B5T_RS21530	COG1121	(ABC) transporter
B5T_RS21535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_RS21540	COG0534	Mate efflux family protein
B5T_RS21605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_RS21610	COG1773	rubredoxin
B5T_RS21615	COG3161	chorismate lyase activity
B5T_RS21620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B5T_RS21635	COG2900	Belongs to the SlyX family
B5T_RS21640	COG1309	transcriptional regulator
B5T_RS21650	COG2119	membrane
B5T_RS21655	COG4681	YaeQ
B5T_RS21665	COG0431	NADPH-dependent FMN reductase
B5T_RS21670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B5T_RS21675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5T_RS21680	COG0640	Transcriptional regulator
B5T_RS21690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B5T_RS21695	COG0581	inorganic phosphate transmembrane transporter activity
B5T_RS21700	COG0573	inorganic phosphate transmembrane transporter activity
B5T_RS21705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5T_RS21720	COG1607	acyl-coa hydrolase
B5T_RS21725	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B5T_RS21730	COG0210	DNA helicase
B5T_RS21750	COG3284	Transcriptional regulator
B5T_RS21765	COG1012	belongs to the aldehyde dehydrogenase family
B5T_RS21795	COG4172	Belongs to the ABC transporter superfamily
B5T_RS21800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5T_RS21805	COG0601	transmembrane transport
B5T_RS21810	COG0747	negative chemotaxis
B5T_RS21835	COG0824	Thioesterase
B5T_RS21840	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS21845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5T_RS21850	COG1970	mechanosensitive ion channel activity
B5T_RS21855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_RS21855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_RS21860	COG0737	Belongs to the 5'-nucleotidase family
B5T_RS21870	COG0583	DNA-binding transcription factor activity
B5T_RS21885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B5T_RS21935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B5T_RS21940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B5T_RS21945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B5T_RS21950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B5T_RS21955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B5T_RS21960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B5T_RS21965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B5T_RS21970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B5T_RS21980	COG0356	it plays a direct role in the translocation of protons across the membrane
B5T_RS21990	COG1475	DNA binding
B5T_RS21995	COG1192	Involved in chromosome partitioning
B5T_RS22000	COG0357	Ribosomal RNA small subunit methyltransferase G
B5T_RS22005	COG0445	tRNA wobble uridine modification
B5T_RS22015	COG0300	oxidoreductase activity
B5T_RS22020	COG1960	acyl-CoA dehydrogenase activity
B5T_RS22025	COG0546	phosphoglycolate phosphatase activity
B5T_RS22035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_RS22040	COG1278	Cold shock
B5T_RS22060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_RS22070	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_RS22090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B5T_RS22095	COG0706	membrane insertase activity
B5T_RS22100	COG0594	ribonuclease P activity
B5T_RS22115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B5T_RS22160	COG2207	Transcriptional regulator
B5T_RS22185	COG0739	heme binding
B5T_RS22220	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_RS22225	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_RS22270	COG1216	Glycosyl transferase, family 2
B5T_RS22300	COG2853	Lipoprotein