locus-tag	class	description
ASALC70_RS00020	COG0784	Response regulator, receiver
ASALC70_RS00020	COG5002	protein histidine kinase activity
ASALC70_RS00025	COG2205	protein histidine kinase activity
ASALC70_RS00025	COG2202	Pas domain
ASALC70_RS00030	COG5002	protein histidine kinase activity
ASALC70_RS00030	COG2198	Histidine kinase
ASALC70_RS00030	COG0784	Response regulator, receiver
ASALC70_RS00040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_RS00120	COG3848	Pyruvate phosphate dikinase
ASALC70_RS00120	COG0574	Belongs to the PEP-utilizing enzyme family
ASALC70_RS00150	COG4974	Belongs to the 'phage' integrase family
ASALC70_RS00190	COG2813	Specifically methylates the guanine in position
ASALC70_RS00200	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ASALC70_RS00205	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ASALC70_RS00210	COG0235	Class ii aldolase
ASALC70_RS00215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ASALC70_RS00260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASALC70_RS00260	COG0512	Glutamine amidotransferase of anthranilate synthase
ASALC70_RS00265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASALC70_RS00270	COG1802	Transcriptional regulator
ASALC70_RS00280	COG0372	Belongs to the citrate synthase family
ASALC70_RS00285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASALC70_RS00290	COG2828	Protein conserved in bacteria
ASALC70_RS00295	COG2079	MmgE PrpD family protein
ASALC70_RS00315	COG0741	lytic transglycosylase activity
ASALC70_RS00315	COG1196	nuclear chromosome segregation
ASALC70_RS00315	COG0739	heme binding
ASALC70_RS00320	COG0069	glutamate synthase activity
ASALC70_RS00335	COG1192	Involved in chromosome partitioning
ASALC70_RS00365	COG2885	chlorophyll binding
ASALC70_RS00370	COG0277	FAD linked oxidase domain protein
ASALC70_RS00370	COG0277	FAD linked oxidase domain protein
ASALC70_RS00375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASALC70_RS00400	COG2814	Major facilitator Superfamily
ASALC70_RS00415	COG4181	ATPase activity
ASALC70_RS00440	COG0204	Acyl-transferase
ASALC70_RS00445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_RS00460	COG2350	Protein conserved in bacteria
ASALC70_RS00465	COG2917	probably involved in intracellular septation
ASALC70_RS00475	COG0009	L-threonylcarbamoyladenylate synthase
ASALC70_RS00480	COG0180	Tryptophanyl-tRNA synthetase
ASALC70_RS00490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASALC70_RS00505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASALC70_RS00515	COG0697	spore germination
ASALC70_RS00520	COG0330	HflC and HflK could
ASALC70_RS00540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASALC70_RS00550	COG0840	transmembrane signaling receptor activity
ASALC70_RS00565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASALC70_RS00585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_RS00595	COG2010	Cytochrome c
ASALC70_RS00595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_RS00600	COG2080	2 iron, 2 sulfur cluster binding
ASALC70_RS00605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_RS00605	COG2010	Cytochrome c
ASALC70_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS00635	COG3473	Maleate cis-trans isomerase
ASALC70_RS00640	COG1335	isochorismatase
ASALC70_RS00755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_RS00765	COG3022	response to hydroperoxide
ASALC70_RS00775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_RS00780	COG0598	Magnesium transport protein CorA
ASALC70_RS00795	COG0700	Nucleoside recognition
ASALC70_RS00855	COG2267	carboxylic ester hydrolase activity
ASALC70_RS00860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_RS00865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASALC70_RS00870	COG0564	pseudouridine synthase activity
ASALC70_RS00895	COG0501	Belongs to the peptidase M48B family
ASALC70_RS00905	COG0534	Mate efflux family protein
ASALC70_RS00930	COG0604	alcohol dehydrogenase
ASALC70_RS00935	COG0616	signal peptide processing
ASALC70_RS00945	COG2816	NAD+ diphosphatase activity
ASALC70_RS00970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_RS00975	COG0328	RNA-DNA hybrid ribonuclease activity
ASALC70_RS00985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_RS00990	COG0741	lytic transglycosylase activity
ASALC70_RS00990	COG1388	LysM domain
ASALC70_RS00995	COG4166	transmembrane transport
ASALC70_RS01000	COG4166	transmembrane transport
ASALC70_RS01005	COG4174	ABC transporter (Permease)
ASALC70_RS01010	COG4239	(ABC) transporter, permease
ASALC70_RS01025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_RS01045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASALC70_RS01050	COG0740	serine-type endopeptidase activity
ASALC70_RS01075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASALC70_RS01095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_RS01110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_RS01170	COG2010	Cytochrome c
ASALC70_RS01170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_RS01190	COG2814	Major facilitator Superfamily
ASALC70_RS01200	COG3119	arylsulfatase activity
ASALC70_RS01210	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_RS01215	COG2207	Transcriptional regulator
ASALC70_RS01220	COG0824	Thioesterase
ASALC70_RS01235	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_RS01240	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_RS01260	COG0587	DNA-directed DNA polymerase activity
ASALC70_RS01265	COG3268	Saccharopine dehydrogenase
ASALC70_RS01310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_RS01315	COG1518	maintenance of DNA repeat elements
ASALC70_RS01330	COG1857	crispr-associated protein
ASALC70_RS01360	COG1203	CRISPR-associated helicase, Cas3
ASALC70_RS01365	COG1203	CRISPR-associated helicase, Cas3
ASALC70_RS01400	COG2308	Evidence 4 Homologs of previously reported genes of
ASALC70_RS01430	COG0583	DNA-binding transcription factor activity
ASALC70_RS01440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASALC70_RS01450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASALC70_RS01460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_RS01465	COG0243	molybdopterin cofactor binding
ASALC70_RS01470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_RS01475	COG2146	nitrite reductase [NAD(P)H] activity
ASALC70_RS01480	COG2146	nitrite reductase [NAD(P)H] activity
ASALC70_RS01480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_RS01485	COG2223	nitrite transmembrane transporter activity
ASALC70_RS01495	COG2815	serine threonine protein kinase
ASALC70_RS01495	COG0515	serine threonine protein kinase
ASALC70_RS01515	COG1104	cysteine desulfurase activity
ASALC70_RS01545	COG0437	4 iron, 4 sulfur cluster binding
ASALC70_RS01550	COG0437	4 iron, 4 sulfur cluster binding
ASALC70_RS01590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_RS01595	COG1845	cytochrome c oxidase, subunit III
ASALC70_RS01605	COG0069	glutamate synthase activity
ASALC70_RS01635	COG0084	hydrolase, TatD family'
ASALC70_RS01655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASALC70_RS01660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASALC70_RS01675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASALC70_RS01690	COG0416	fatty acid biosynthetic process
ASALC70_RS01695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASALC70_RS01700	COG1399	metal-binding, possibly nucleic acid-binding protein
ASALC70_RS01710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASALC70_RS01710	COG0616	signal peptide processing
ASALC70_RS01715	COG0546	phosphoglycolate phosphatase activity
ASALC70_RS01740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS01750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASALC70_RS01755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASALC70_RS01760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASALC70_RS01765	COG1663	tetraacyldisaccharide 4'-kinase activity
ASALC70_RS01770	COG1132	(ABC) transporter
ASALC70_RS01775	COG0848	biopolymer transport protein
ASALC70_RS01780	COG0811	peptide transport
ASALC70_RS01785	COG2333	competence protein COMEC
ASALC70_RS01785	COG0658	competence protein
ASALC70_RS01795	COG1136	(ABC) transporter
ASALC70_RS01815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_RS01820	COG1307	EDD domain protein, DegV family
ASALC70_RS01830	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ASALC70_RS01835	COG0788	formyltetrahydrofolate deformylase activity
ASALC70_RS01850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS01855	COG1131	(ABC) transporter
ASALC70_RS01860	COG0842	Transport permease protein
ASALC70_RS01875	COG1301	dicarboxylic acid transport
ASALC70_RS01890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS01900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_RS01930	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASALC70_RS01935	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ASALC70_RS01950	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASALC70_RS01955	COG1687	branched-chain amino acid
ASALC70_RS01970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS01975	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASALC70_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASALC70_RS01985	COG4558	Periplasmic binding protein
ASALC70_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_RS02075	COG2144	transferase activity, transferring acyl groups
ASALC70_RS02090	COG1024	Enoyl-CoA hydratase
ASALC70_RS02090	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_RS02095	COG0183	Belongs to the thiolase family
ASALC70_RS02110	COG2840	Smr protein MutS2
ASALC70_RS02115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASALC70_RS02125	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASALC70_RS02135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASALC70_RS02140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASALC70_RS02155	COG0717	Belongs to the dCTP deaminase family
ASALC70_RS02160	COG0489	protein tyrosine kinase activity
ASALC70_RS02180	COG0450	alkyl hydroperoxide reductase
ASALC70_RS02190	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASALC70_RS02205	COG2813	Specifically methylates the guanine in position
ASALC70_RS02215	COG0741	lytic transglycosylase activity
ASALC70_RS02230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_RS02235	COG3001	Fructosamine kinase
ASALC70_RS02265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASALC70_RS02285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASALC70_RS02290	COG0585	pseudouridine synthase activity
ASALC70_RS02295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASALC70_RS02300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASALC70_RS02305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASALC70_RS02310	COG0148	phosphopyruvate hydratase activity
ASALC70_RS02315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASALC70_RS02320	COG0504	CTP synthase activity
ASALC70_RS02325	COG0037	tRNA processing
ASALC70_RS02340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASALC70_RS02345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_RS02350	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_RS02355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASALC70_RS02360	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_RS02370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASALC70_RS02385	COG0575	Belongs to the CDS family
ASALC70_RS02390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASALC70_RS02395	COG0233	cytoplasmic translational termination
ASALC70_RS02400	COG0528	UMP kinase activity
ASALC70_RS02405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASALC70_RS02410	COG0052	Belongs to the universal ribosomal protein uS2 family
ASALC70_RS02415	COG0024	Methionine aminopeptidase
ASALC70_RS02420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASALC70_RS02435	COG1393	Belongs to the ArsC family
ASALC70_RS02440	COG2171	N-acyltransferase activity
ASALC70_RS02470	COG0742	ribosomal rna small subunit methyltransferase
ASALC70_RS02480	COG1968	undecaprenyl-diphosphatase activity
ASALC70_RS02490	COG1214	PFAM Peptidase M22, glycoprotease
ASALC70_RS02495	COG1199	ATP-dependent helicase activity
ASALC70_RS02500	COG1199	ATP-dependent helicase activity
ASALC70_RS02505	COG1199	ATP-dependent helicase activity
ASALC70_RS02525	COG2326	polyphosphate kinase activity
ASALC70_RS02530	COG0004	ammonium transporteR
ASALC70_RS02550	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS02555	COG0850	regulation of cytokinetic process
ASALC70_RS02565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASALC70_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS02635	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS02640	COG2030	dehydratase
ASALC70_RS02650	COG0657	acetylesterase activity
ASALC70_RS02675	COG0531	amino acid
ASALC70_RS02685	COG1254	Belongs to the acylphosphatase family
ASALC70_RS02690	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_RS02690	COG1295	ribonuclease BN
ASALC70_RS02695	COG1393	Belongs to the ArsC family
ASALC70_RS02735	COG0714	Associated with various cellular activities
ASALC70_RS02750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_RS02755	COG4771	TonB-dependent receptor
ASALC70_RS02765	COG1595	DNA-templated transcription, initiation
ASALC70_RS02775	COG3101	peptidyl-lysine hydroxylation
ASALC70_RS02845	COG3077	Addiction module antitoxin, RelB DinJ family
ASALC70_RS02885	COG0545	Peptidyl-prolyl cis-trans isomerase
ASALC70_RS02890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASALC70_RS02970	COG0583	DNA-binding transcription factor activity
ASALC70_RS03005	COG0584	glycerophosphoryl diester phosphodiesterase
ASALC70_RS03035	COG1477	protein flavinylation
ASALC70_RS03045	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_RS03075	COG1946	Acyl-CoA thioesterase
ASALC70_RS03090	COG2081	HI0933 family
ASALC70_RS03100	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASALC70_RS03110	COG1472	Belongs to the glycosyl hydrolase 3 family
ASALC70_RS03135	COG0589	response to stress
ASALC70_RS03165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASALC70_RS03175	COG0084	hydrolase, TatD family'
ASALC70_RS03180	COG1739	Uncharacterized protein family UPF0029
ASALC70_RS03195	COG0436	Aminotransferase
ASALC70_RS03210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASALC70_RS03220	COG1215	transferase activity, transferring glycosyl groups
ASALC70_RS03225	COG1215	transferase activity, transferring glycosyl groups
ASALC70_RS03255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASALC70_RS03260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASALC70_RS03265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASALC70_RS03275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASALC70_RS03325	COG1741	Belongs to the pirin family
ASALC70_RS03330	COG0427	acetyl-CoA hydrolase
ASALC70_RS03365	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS03375	COG4566	intracellular signal transduction
ASALC70_RS03380	COG4890	Cyd operon protein YbgT
ASALC70_RS03400	COG4988	ABC transporter
ASALC70_RS03405	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASALC70_RS03410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASALC70_RS03415	COG0840	transmembrane signaling receptor activity
ASALC70_RS03430	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASALC70_RS03440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASALC70_RS03450	COG2137	regulation of response to DNA damage stimulus
ASALC70_RS03490	COG3712	iron ion homeostasis
ASALC70_RS03495	COG4771	TonB-dependent receptor
ASALC70_RS03505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASALC70_RS03510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASALC70_RS03545	COG1487	ribonuclease activity
ASALC70_RS03555	COG2814	Major facilitator Superfamily
ASALC70_RS03570	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ASALC70_RS03600	COG1569	PIN domain
ASALC70_RS03605	COG3311	Transcriptional regulator
ASALC70_RS03690	COG2132	Multicopper oxidase
ASALC70_RS03695	COG2132	Multicopper oxidase
ASALC70_RS03710	COG2132	Multicopper oxidase
ASALC70_RS03735	COG3077	Addiction module antitoxin, RelB DinJ family
ASALC70_RS03785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASALC70_RS03830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASALC70_RS03860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASALC70_RS03910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_RS03915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_RS03920	COG1509	lysine 2,3-aminomutase activity
ASALC70_RS03925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_RS03930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_RS03945	COG1074	ATP-dependent DNA helicase activity
ASALC70_RS03955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASALC70_RS04000	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS04015	COG0776	regulation of translation
ASALC70_RS04020	COG0072	phenylalanine-tRNA ligase activity
ASALC70_RS04030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASALC70_RS04040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASALC70_RS04080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_RS04085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASALC70_RS04090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASALC70_RS04100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASALC70_RS04110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASALC70_RS04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_RS04120	COG0425	Belongs to the sulfur carrier protein TusA family
ASALC70_RS04125	COG4783	chaperone-mediated protein folding
ASALC70_RS04130	COG4773	Receptor
ASALC70_RS04150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASALC70_RS04155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_RS04175	COG0415	Belongs to the DNA photolyase family
ASALC70_RS04180	COG0789	Transcriptional regulator
ASALC70_RS04200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASALC70_RS04215	COG2885	chlorophyll binding
ASALC70_RS04220	COG0823	Involved in the tonB-independent uptake of proteins
ASALC70_RS04240	COG0824	Thioesterase
ASALC70_RS04245	COG2255	four-way junction helicase activity
ASALC70_RS04250	COG0632	four-way junction helicase activity
ASALC70_RS04255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASALC70_RS04260	COG0217	transcriptional regulatory protein
ASALC70_RS04265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASALC70_RS04300	COG0729	surface antigen
ASALC70_RS04325	COG1192	Involved in chromosome partitioning
ASALC70_RS04335	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS04340	COG1309	transcriptional regulator
ASALC70_RS04350	COG0514	ATP-dependent DNA helicase (RecQ)
ASALC70_RS04355	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASALC70_RS04370	COG0513	Belongs to the DEAD box helicase family
ASALC70_RS04410	COG4067	protein conserved in archaea
ASALC70_RS04410	COG0189	ligase activity
ASALC70_RS04415	COG0137	argininosuccinate synthase activity
ASALC70_RS04420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_RS04425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASALC70_RS04460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASALC70_RS04465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASALC70_RS04485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASALC70_RS04495	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS04505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASALC70_RS04525	COG0737	Belongs to the 5'-nucleotidase family
ASALC70_RS04605	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_RS04610	COG3384	dioxygenase
ASALC70_RS04620	COG3971	2-oxopent-4-enoate hydratase activity
ASALC70_RS04635	COG1846	Transcriptional regulator
ASALC70_RS04640	COG0861	Integral membrane protein TerC family
ASALC70_RS04705	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASALC70_RS04715	COG1309	transcriptional regulator
ASALC70_RS04745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS04745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_RS04775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASALC70_RS04830	COG0412	Dienelactone hydrolase
ASALC70_RS04870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASALC70_RS04880	COG1611	Belongs to the LOG family
ASALC70_RS04895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASALC70_RS04915	COG1280	lysine exporter protein (LysE YggA)
ASALC70_RS04935	COG0735	belongs to the Fur family
ASALC70_RS04945	COG4221	oxidoreductase activity
ASALC70_RS04965	COG1024	Enoyl-CoA hydratase
ASALC70_RS05010	COG0183	Belongs to the thiolase family
ASALC70_RS05020	COG4993	Dehydrogenase
ASALC70_RS05025	COG4993	Dehydrogenase
ASALC70_RS05040	COG3237	CsbD-like
ASALC70_RS05055	COG0589	response to stress
ASALC70_RS05060	COG0659	secondary active sulfate transmembrane transporter activity
ASALC70_RS05065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASALC70_RS05070	COG1191	sigma factor activity
ASALC70_RS05125	COG2201	protein-glutamate methylesterase activity
ASALC70_RS05130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_RS05135	COG0840	transmembrane signaling receptor activity
ASALC70_RS05200	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASALC70_RS05205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASALC70_RS05210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASALC70_RS05250	COG1677	Flagellar hook-basal body complex protein FliE
ASALC70_RS05260	COG1766	The M ring may be actively involved in energy transduction
ASALC70_RS05265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASALC70_RS05330	COG1987	bacterial-type flagellum assembly
ASALC70_RS05340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASALC70_RS05370	COG4787	bacterial-type flagellum-dependent cell motility
ASALC70_RS05375	COG1749	Flagellar hook protein flgE
ASALC70_RS05380	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASALC70_RS05385	COG1558	bacterial-type flagellum-dependent cell motility
ASALC70_RS05410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASALC70_RS05445	COG0459	protein refolding
ASALC70_RS05450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASALC70_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS05465	COG2807	transmembrane transport
ASALC70_RS05475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASALC70_RS05480	COG2096	Adenosyltransferase
ASALC70_RS05485	COG2205	protein histidine kinase activity
ASALC70_RS05490	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS05530	COG1115	amino acid carrier protein
ASALC70_RS05585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASALC70_RS05590	COG0237	dephospho-CoA kinase activity
ASALC70_RS05595	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASALC70_RS05610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASALC70_RS05615	COG0653	protein targeting
ASALC70_RS05620	COG0739	heme binding
ASALC70_RS05630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASALC70_RS05645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASALC70_RS05650	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASALC70_RS05660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASALC70_RS05665	COG0772	Belongs to the SEDS family
ASALC70_RS05670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASALC70_RS05675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASALC70_RS05680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASALC70_RS05685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASALC70_RS05715	COG0275	rRNA processing
ASALC70_RS05720	COG0275	rRNA processing
ASALC70_RS05725	COG2001	Belongs to the MraZ family
ASALC70_RS05730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_RS05730	COG0426	domain, Protein
ASALC70_RS05750	COG0792	nuclease activity
ASALC70_RS05760	COG2823	Periplasmic or secreted lipoprotein
ASALC70_RS05775	COG2857	Cytochrome c1
ASALC70_RS05780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASALC70_RS05785	COG0723	plastoquinol--plastocyanin reductase activity
ASALC70_RS05800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASALC70_RS05805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASALC70_RS05810	COG0667	Aldo Keto reductase
ASALC70_RS05815	COG1233	COG1233 Phytoene dehydrogenase and related
ASALC70_RS05905	COG2067	long-chain fatty acid transport protein
ASALC70_RS05915	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS05920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASALC70_RS05925	COG2945	thiolester hydrolase activity
ASALC70_RS05935	COG2046	Belongs to the sulfate adenylyltransferase family
ASALC70_RS05940	COG1597	lipid kinase activity
ASALC70_RS05950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_RS05960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASALC70_RS05970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASALC70_RS05975	COG5007	Belongs to the BolA IbaG family
ASALC70_RS05990	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASALC70_RS06005	COG1137	ATPase activity
ASALC70_RS06010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASALC70_RS06025	COG1660	Displays ATPase and GTPase activities
ASALC70_RS06035	COG2239	Acts as a magnesium transporter
ASALC70_RS06055	COG3028	Belongs to the UPF0307 family
ASALC70_RS06060	COG2807	transmembrane transport
ASALC70_RS06075	COG0477	Major facilitator Superfamily
ASALC70_RS06085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_RS06090	COG0312	modulator of DNA gyrase
ASALC70_RS06095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_RS06115	COG0424	maF-like protein
ASALC70_RS06120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASALC70_RS06125	COG1792	Involved in formation and maintenance of cell shape
ASALC70_RS06130	COG1077	Cell shape determining protein MreB Mrl
ASALC70_RS06135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASALC70_RS06140	COG0154	amidase activity
ASALC70_RS06145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASALC70_RS06150	COG1024	Enoyl-CoA hydratase
ASALC70_RS06210	COG0848	biopolymer transport protein
ASALC70_RS06240	COG1595	DNA-templated transcription, initiation
ASALC70_RS06275	COG2890	protein-(glutamine-N5) methyltransferase activity
ASALC70_RS06280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASALC70_RS06285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASALC70_RS06295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASALC70_RS06310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASALC70_RS06315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASALC70_RS06330	COG0012	GTP binding
ASALC70_RS06365	COG0297	glycogen (starch) synthase activity
ASALC70_RS06385	COG1045	serine acetyltransferase
ASALC70_RS06405	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_RS06420	COG0154	amidase activity
ASALC70_RS06425	COG0436	Aminotransferase
ASALC70_RS06435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASALC70_RS06440	COG1862	Preprotein translocase
ASALC70_RS06445	COG0343	queuine tRNA-ribosyltransferase activity
ASALC70_RS06450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASALC70_RS06460	COG1309	transcriptional regulator
ASALC70_RS06465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_RS06480	COG0633	Ferredoxin
ASALC70_RS06500	COG0657	acetylesterase activity
ASALC70_RS06550	COG2030	dehydratase
ASALC70_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS06570	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS06580	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASALC70_RS06660	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS06695	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_RS06700	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_RS06705	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_RS06710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASALC70_RS06740	COG1597	lipid kinase activity
ASALC70_RS06770	COG1183	phosphatidylcholine synthase activity
ASALC70_RS06775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASALC70_RS06780	COG0583	DNA-binding transcription factor activity
ASALC70_RS06805	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS06860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASALC70_RS06860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_RS06920	COG4966	pilus assembly protein PilW
ASALC70_RS06935	COG4969	Belongs to the N-Me-Phe pilin family
ASALC70_RS06940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASALC70_RS06960	COG0196	riboflavin kinase activity
ASALC70_RS06970	COG0268	Binds directly to 16S ribosomal RNA
ASALC70_RS06980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASALC70_RS06985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASALC70_RS06990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASALC70_RS06995	COG0142	geranyltranstransferase activity
ASALC70_RS07040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_RS07055	COG0784	Response regulator, receiver
ASALC70_RS07055	COG2205	protein histidine kinase activity
ASALC70_RS07055	COG5002	protein histidine kinase activity
ASALC70_RS07080	COG0778	Nitroreductase
ASALC70_RS07085	COG4221	oxidoreductase activity
ASALC70_RS07120	COG2267	carboxylic ester hydrolase activity
ASALC70_RS07145	COG3031	protein transport across the cell outer membrane
ASALC70_RS07160	COG2814	Major facilitator Superfamily
ASALC70_RS07165	COG2814	Major facilitator Superfamily
ASALC70_RS07170	COG2197	response regulator
ASALC70_RS07195	COG0659	secondary active sulfate transmembrane transporter activity
ASALC70_RS07215	COG0203	ribosomal protein L17
ASALC70_RS07220	COG0202	RNA polymerase activity
ASALC70_RS07225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASALC70_RS07230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASALC70_RS07235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASALC70_RS07240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASALC70_RS07250	COG0200	Binds to the 23S rRNA
ASALC70_RS07255	COG1841	ribosomal large subunit assembly
ASALC70_RS07260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASALC70_RS07265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASALC70_RS07270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASALC70_RS07275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASALC70_RS07280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASALC70_RS07285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASALC70_RS07290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASALC70_RS07295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASALC70_RS07300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASALC70_RS07305	COG0255	Belongs to the universal ribosomal protein uL29 family
ASALC70_RS07310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASALC70_RS07315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASALC70_RS07320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASALC70_RS07325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASALC70_RS07330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASALC70_RS07335	COG0089	rRNA binding
ASALC70_RS07340	COG0088	Forms part of the polypeptide exit tunnel
ASALC70_RS07345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASALC70_RS07350	COG0051	transcription antitermination factor activity, RNA binding
ASALC70_RS07360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASALC70_RS07365	COG0049	tRNA binding
ASALC70_RS07370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASALC70_RS07375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASALC70_RS07380	COG0085	RNA polymerase activity
ASALC70_RS07385	COG0222	ribosome binding
ASALC70_RS07390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASALC70_RS07400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASALC70_RS07420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASALC70_RS07455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASALC70_RS07460	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASALC70_RS07460	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASALC70_RS07470	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS07475	COG1022	Amp-dependent synthetase and ligase
ASALC70_RS07485	COG2433	Pfam Transposase IS66
ASALC70_RS07495	COG2963	transposase activity
ASALC70_RS07525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASALC70_RS07530	COG0739	heme binding
ASALC70_RS07545	COG0316	Belongs to the HesB IscA family
ASALC70_RS07570	COG1981	membrane
ASALC70_RS07580	COG0352	thiamine-phosphate diphosphorylase activity
ASALC70_RS07615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASALC70_RS07620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASALC70_RS07640	COG0436	Aminotransferase
ASALC70_RS07650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASALC70_RS07665	COG3852	Histidine kinase
ASALC70_RS07685	COG1428	Deoxynucleoside kinase
ASALC70_RS07690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASALC70_RS07695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASALC70_RS07700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASALC70_RS07705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_RS07710	COG2814	Major facilitator Superfamily
ASALC70_RS07715	COG1566	PFAM secretion protein HlyD family protein
ASALC70_RS07725	COG1185	polyribonucleotide nucleotidyltransferase activity
ASALC70_RS07735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASALC70_RS07740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASALC70_RS07745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASALC70_RS07750	COG0195	Participates in both transcription termination and antitermination
ASALC70_RS07755	COG0779	Required for maturation of 30S ribosomal subunits
ASALC70_RS07775	COG0149	triose-phosphate isomerase activity
ASALC70_RS07780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASALC70_RS07785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASALC70_RS07795	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASALC70_RS07810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASALC70_RS07820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASALC70_RS07830	COG0443	Heat shock 70 kDa protein
ASALC70_RS07835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASALC70_RS07840	COG1420	regulation of RNA biosynthetic process
ASALC70_RS07845	COG0497	DNA recombination
ASALC70_RS07865	COG0733	neurotransmitter:sodium symporter activity
ASALC70_RS07870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASALC70_RS07905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS07930	COG1802	Transcriptional regulator
ASALC70_RS07950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS07985	COG2807	transmembrane transport
ASALC70_RS08005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_RS08010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_RS08015	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASALC70_RS08075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_RS08075	COG2226	methyltransferase
ASALC70_RS08075	COG0596	Alpha beta hydrolase
ASALC70_RS08085	COG1116	anion transmembrane transporter activity
ASALC70_RS08090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASALC70_RS08120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_RS08120	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_RS08130	COG1522	sequence-specific DNA binding
ASALC70_RS08170	COG3540	Alkaline phosphatase
ASALC70_RS08180	COG1881	PFAM PEBP family protein
ASALC70_RS08195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASALC70_RS08200	COG2226	methyltransferase
ASALC70_RS08205	COG0596	Alpha beta hydrolase
ASALC70_RS08210	COG0156	8-amino-7-oxononanoate synthase activity
ASALC70_RS08230	COG2045	Belongs to the ComB family
ASALC70_RS08240	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASALC70_RS08295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASALC70_RS08300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASALC70_RS08350	COG0281	malic enzyme
ASALC70_RS08355	COG0254	rRNA binding
ASALC70_RS08360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASALC70_RS08365	COG0477	Major facilitator Superfamily
ASALC70_RS08385	COG1566	PFAM secretion protein HlyD family protein
ASALC70_RS08390	COG0018	arginyl-trna synthetase
ASALC70_RS08405	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASALC70_RS08410	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASALC70_RS08425	COG2226	methyltransferase
ASALC70_RS08435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_RS08440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_RS08450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASALC70_RS08455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASALC70_RS08465	COG1073	alpha beta
ASALC70_RS08485	COG1490	D-aminoacyl-tRNA deacylase activity
ASALC70_RS08510	COG3852	Histidine kinase
ASALC70_RS08525	COG0174	glutamine synthetase
ASALC70_RS08530	COG0425	Belongs to the sulfur carrier protein TusA family
ASALC70_RS08535	COG0482	sulfurtransferase activity
ASALC70_RS08540	COG3083	sulfuric ester hydrolase activity
ASALC70_RS08570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASALC70_RS08595	COG4942	peptidase
ASALC70_RS08610	COG0385	Bile acid
ASALC70_RS08625	COG1671	Belongs to the UPF0178 family
ASALC70_RS08630	COG0107	imidazoleglycerol-phosphate synthase activity
ASALC70_RS08640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASALC70_RS08645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASALC70_RS08650	COG0131	Imidazoleglycerol-phosphate dehydratase
ASALC70_RS08685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASALC70_RS08815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS08825	COG1116	anion transmembrane transporter activity
ASALC70_RS08830	COG1309	transcriptional regulator
ASALC70_RS08835	COG0174	glutamine synthetase
ASALC70_RS08840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_RS08855	COG0739	heme binding
ASALC70_RS08865	COG1335	isochorismatase
ASALC70_RS08870	COG3845	ABC transporter
ASALC70_RS08885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_RS08895	COG1079	Belongs to the binding-protein-dependent transport system permease family
ASALC70_RS08900	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASALC70_RS08915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS08945	COG0583	DNA-binding transcription factor activity
ASALC70_RS08965	COG1802	Transcriptional regulator
ASALC70_RS08985	COG0411	ABC transporter
ASALC70_RS09010	COG1733	regulation of RNA biosynthetic process
ASALC70_RS09020	COG0024	Methionine aminopeptidase
ASALC70_RS09075	COG0656	L-ascorbic acid biosynthetic process
ASALC70_RS09085	COG2207	Transcriptional regulator
ASALC70_RS09090	COG4221	oxidoreductase activity
ASALC70_RS09155	COG3239	Fatty acid desaturase
ASALC70_RS09170	COG4774	siderophore transport
ASALC70_RS09175	COG3547	Transposase (IS116 IS110 IS902 family)
ASALC70_RS09185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_RS09245	COG3093	addiction module antidote protein HigA
ASALC70_RS09255	COG2375	cellular response to nickel ion
ASALC70_RS09285	COG0183	Belongs to the thiolase family
ASALC70_RS09305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_RS09310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_RS09315	COG2031	fatty acid transporter
ASALC70_RS09345	COG4977	sequence-specific DNA binding
ASALC70_RS09350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASALC70_RS09355	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_RS09385	COG0583	DNA-binding transcription factor activity
ASALC70_RS09410	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS09415	COG2072	flavoprotein involved in K transport
ASALC70_RS09450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_RS09465	COG0444	Belongs to the ABC transporter superfamily
ASALC70_RS09470	COG4608	Belongs to the ABC transporter superfamily
ASALC70_RS09485	COG0601	transmembrane transport
ASALC70_RS09495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASALC70_RS09525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASALC70_RS09560	COG4206	TonB-dependent receptor
ASALC70_RS09565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASALC70_RS09570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASALC70_RS09575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASALC70_RS09585	COG1492	cobalamin metabolic process
ASALC70_RS09615	COG0494	nUDIX hydrolase
ASALC70_RS09635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_RS09640	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS09645	COG0583	DNA-binding transcription factor activity
ASALC70_RS09665	COG2217	Heavy metal translocating P-type atpase
ASALC70_RS09740	COG0730	response to heat
ASALC70_RS09815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS09825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_RS09835	COG0154	amidase activity
ASALC70_RS09855	COG1278	Cold shock
ASALC70_RS09880	COG0628	permease
ASALC70_RS09885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASALC70_RS09900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASALC70_RS09935	COG1360	Flagellar Motor Protein
ASALC70_RS09955	COG0625	glutathione transferase activity
ASALC70_RS09960	COG2824	Alkylphosphonate utilization operon protein PhnA
ASALC70_RS10020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ASALC70_RS10090	COG3712	iron ion homeostasis
ASALC70_RS10125	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_RS10155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_RS10160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_RS10165	COG0509	glycine decarboxylation via glycine cleavage system
ASALC70_RS10170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASALC70_RS10190	COG2223	nitrite transmembrane transporter activity
ASALC70_RS10220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS10225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS10235	COG3079	Belongs to the UPF0149 family
ASALC70_RS10255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASALC70_RS10270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASALC70_RS10325	COG0583	DNA-binding transcription factor activity
ASALC70_RS10330	COG1228	amidohydrolase
ASALC70_RS10350	COG0126	phosphoglycerate kinase activity
ASALC70_RS10355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASALC70_RS10360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASALC70_RS10365	COG0640	Transcriptional regulator
ASALC70_RS10370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASALC70_RS10375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASALC70_RS10380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASALC70_RS10395	COG1307	EDD domain protein, DegV family
ASALC70_RS10430	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ASALC70_RS10445	COG0534	Mate efflux family protein
ASALC70_RS10470	COG0742	ribosomal rna small subunit methyltransferase
ASALC70_RS10485	COG0612	Peptidase, M16
ASALC70_RS10495	COG2884	Cell division ATP-binding protein ftsE
ASALC70_RS10500	COG2177	Part of the ABC transporter FtsEX involved in
ASALC70_RS10510	COG2363	Small membrane protein
ASALC70_RS10520	COG2022	thiamine diphosphate biosynthetic process
ASALC70_RS10525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASALC70_RS10565	COG0693	protein deglycase activity
ASALC70_RS10570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_RS10575	COG2813	Specifically methylates the guanine in position
ASALC70_RS10575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_RS10580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASALC70_RS10585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASALC70_RS10590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS10595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_RS10675	COG4964	Belongs to the GSP D family
ASALC70_RS10700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASALC70_RS10705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASALC70_RS10710	COG2003	Belongs to the UPF0758 family
ASALC70_RS10715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASALC70_RS10720	COG0756	dUTP diphosphatase activity
ASALC70_RS10740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASALC70_RS10755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASALC70_RS10760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASALC70_RS10765	COG1561	YicC-like family, N-terminal region
ASALC70_RS10770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_RS10775	COG1725	Transcriptional regulator
ASALC70_RS10830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_RS10835	COG3608	succinylglutamate desuccinylase aspartoacylase
ASALC70_RS10845	COG1758	RNA polymerase activity
ASALC70_RS10850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASALC70_RS10875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASALC70_RS10880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASALC70_RS10890	COG0583	DNA-binding transcription factor activity
ASALC70_RS10895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASALC70_RS10900	COG5507	3-demethylubiquinone-9 3-methyltransferase
ASALC70_RS10930	COG0583	DNA-binding transcription factor activity
ASALC70_RS10975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASALC70_RS10985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASALC70_RS10990	COG0408	coproporphyrinogen oxidase activity
ASALC70_RS10995	COG0009	L-threonylcarbamoyladenylate synthase
ASALC70_RS11000	COG0758	DNA mediated transformation
ASALC70_RS11005	COG0758	DNA mediated transformation
ASALC70_RS11020	COG0242	peptide deformylase activity
ASALC70_RS11040	COG0569	domain protein
ASALC70_RS11055	COG2186	Transcriptional regulator
ASALC70_RS11080	COG3039	Transposase
ASALC70_RS11120	COG2132	Multicopper oxidase
ASALC70_RS11125	COG2132	Multicopper oxidase
ASALC70_RS11225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASALC70_RS11270	COG1764	response to oxidative stress
ASALC70_RS11285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASALC70_RS11305	COG4771	TonB-dependent receptor
ASALC70_RS11310	COG1858	cytochrome C peroxidase
ASALC70_RS11315	COG0583	DNA-binding transcription factor activity
ASALC70_RS11335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASALC70_RS11350	COG0540	Belongs to the ATCase OTCase family
ASALC70_RS11365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASALC70_RS11370	COG1678	Uncharacterized ACR, COG1678
ASALC70_RS11380	COG0189	ligase activity
ASALC70_RS11440	COG0643	Histidine kinase
ASALC70_RS11440	COG2198	Histidine kinase
ASALC70_RS11445	COG2201	protein-glutamate methylesterase activity
ASALC70_RS11465	COG3038	cytochrome b561
ASALC70_RS11475	COG1047	Peptidyl-prolyl cis-trans
ASALC70_RS11485	COG0330	HflC and HflK could
ASALC70_RS11495	COG0154	amidase activity
ASALC70_RS11505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASALC70_RS11570	COG4977	sequence-specific DNA binding
ASALC70_RS11610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_RS11615	COG0277	FAD linked oxidase domain protein
ASALC70_RS11620	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASALC70_RS11625	COG0189	ligase activity
ASALC70_RS11625	COG4067	protein conserved in archaea
ASALC70_RS11640	COG0110	maltose O-acetyltransferase activity
ASALC70_RS11645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_RS11645	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_RS11650	COG2818	Glycosylase
ASALC70_RS11655	COG0752	glycyl-tRNA synthetase alpha subunit
ASALC70_RS11660	COG0751	glycine-tRNA ligase activity
ASALC70_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS11730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASALC70_RS11735	COG0592	DNA-directed DNA polymerase activity
ASALC70_RS11740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASALC70_RS11745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASALC70_RS11750	COG0594	ribonuclease P activity
ASALC70_RS11755	COG0706	membrane insertase activity
ASALC70_RS11760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASALC70_RS11775	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS11780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS11785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS11800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASALC70_RS11805	COG1278	Cold shock
ASALC70_RS11810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASALC70_RS11825	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS11830	COG0300	oxidoreductase activity
ASALC70_RS11835	COG3263	regulation of cellular component size
ASALC70_RS11845	COG0445	tRNA wobble uridine modification
ASALC70_RS11850	COG0357	Ribosomal RNA small subunit methyltransferase G
ASALC70_RS11855	COG1192	Involved in chromosome partitioning
ASALC70_RS11860	COG1475	DNA binding
ASALC70_RS11870	COG0356	it plays a direct role in the translocation of protons across the membrane
ASALC70_RS11880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASALC70_RS11885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASALC70_RS11890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASALC70_RS11905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASALC70_RS11910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASALC70_RS11945	COG4221	oxidoreductase activity
ASALC70_RS11955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_RS11955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_RS11960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_RS11965	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS12020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_RS12035	COG1309	transcriptional regulator
ASALC70_RS12040	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS12055	COG0668	transmembrane transport
ASALC70_RS12075	COG0210	DNA helicase
ASALC70_RS12080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASALC70_RS12085	COG1607	acyl-coa hydrolase
ASALC70_RS12090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS12105	COG0573	inorganic phosphate transmembrane transporter activity
ASALC70_RS12115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASALC70_RS12120	COG0704	Plays a role in the regulation of phosphate uptake
ASALC70_RS12125	COG0640	Transcriptional regulator
ASALC70_RS12135	COG0798	PFAM Bile acid sodium symporter
ASALC70_RS12140	COG0431	NADPH-dependent FMN reductase
ASALC70_RS12150	COG4681	YaeQ
ASALC70_RS12155	COG4681	YaeQ
ASALC70_RS12170	COG2900	Belongs to the SlyX family
ASALC70_RS12185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASALC70_RS12190	COG3161	chorismate lyase activity
ASALC70_RS12215	COG0534	Mate efflux family protein
ASALC70_RS12220	COG0534	Mate efflux family protein
ASALC70_RS12225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASALC70_RS12230	COG1121	(ABC) transporter
ASALC70_RS12245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASALC70_RS12265	COG0500	methyltransferase
ASALC70_RS12275	COG1643	Atp-dependent helicase
ASALC70_RS12290	COG0678	peroxiredoxin activity
ASALC70_RS12300	COG0668	transmembrane transport
ASALC70_RS12305	COG0028	Belongs to the TPP enzyme family
ASALC70_RS12310	COG0436	Aminotransferase
ASALC70_RS12330	COG0842	Transport permease protein
ASALC70_RS12335	COG1131	(ABC) transporter
ASALC70_RS12360	COG0154	amidase activity
ASALC70_RS12365	COG0154	amidase activity
ASALC70_RS12370	COG5285	phytanoyl-CoA dioxygenase
ASALC70_RS12380	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS12390	COG2610	gluconate transmembrane transporter activity
ASALC70_RS12395	COG2610	gluconate transmembrane transporter activity
ASALC70_RS12415	COG1160	GTP binding
ASALC70_RS12440	COG1006	Multisubunit Na H antiporter MnhC subunit
ASALC70_RS12445	COG0651	ATP synthesis coupled electron transport
ASALC70_RS12455	COG1863	multisubunit Na H antiporter MnhE subunit
ASALC70_RS12460	COG2212	antiporter activity
ASALC70_RS12470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASALC70_RS12590	COG4964	Belongs to the GSP D family
ASALC70_RS12660	COG0640	Transcriptional regulator
ASALC70_RS12665	COG1272	protein, Hemolysin III
ASALC70_RS12670	COG0783	Belongs to the Dps family
ASALC70_RS12740	COG1024	Enoyl-CoA hydratase
ASALC70_RS12765	COG0385	Bile acid
ASALC70_RS12770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASALC70_RS12775	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS12805	COG1566	PFAM secretion protein HlyD family protein
ASALC70_RS12850	COG1515	deoxyribonuclease V activity
ASALC70_RS12880	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS12895	COG2205	protein histidine kinase activity
ASALC70_RS12900	COG3245	cytochrome
ASALC70_RS12910	COG0210	DNA helicase
ASALC70_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS12940	COG0697	spore germination
ASALC70_RS12945	COG0606	chelatase, subunit chli
ASALC70_RS12950	COG2960	long-chain fatty acid transporting porin activity
ASALC70_RS12955	COG0347	Belongs to the P(II) protein family
ASALC70_RS12960	COG0004	ammonium transporteR
ASALC70_RS12970	COG2995	paraquat-inducible protein a
ASALC70_RS12975	COG3008	intermembrane lipid transfer
ASALC70_RS13015	COG1166	arginine decarboxylase activity
ASALC70_RS13035	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_RS13085	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASALC70_RS13110	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASALC70_RS13135	COG1047	Peptidyl-prolyl cis-trans
ASALC70_RS13140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASALC70_RS13145	COG0288	reversible hydration of carbon dioxide
ASALC70_RS13155	COG2132	Multicopper oxidase
ASALC70_RS13175	COG3852	Histidine kinase
ASALC70_RS13180	COG2204	response regulator
ASALC70_RS13215	COG0347	Belongs to the P(II) protein family
ASALC70_RS13225	COG0463	Glycosyl transferase, family 2
ASALC70_RS13240	COG2963	transposase activity
ASALC70_RS13270	COG0789	Transcriptional regulator
ASALC70_RS13280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASALC70_RS13285	COG0789	Transcriptional regulator
ASALC70_RS13345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS13350	COG1136	(ABC) transporter
ASALC70_RS13350	COG0577	efflux transmembrane transporter activity
ASALC70_RS13360	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASALC70_RS13395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_RS13425	COG0247	lactate metabolic process
ASALC70_RS13430	COG0277	FAD linked oxidase domain protein
ASALC70_RS13440	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS13445	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS13450	COG2205	protein histidine kinase activity
ASALC70_RS13545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASALC70_RS13570	COG4774	siderophore transport
ASALC70_RS13580	COG0531	amino acid
ASALC70_RS13585	COG1982	Orn Lys Arg decarboxylase major
ASALC70_RS13590	COG1982	Orn Lys Arg decarboxylase major
ASALC70_RS13610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASALC70_RS13620	COG0488	(ABC) transporter
ASALC70_RS13650	COG1346	cytolysis
ASALC70_RS13660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASALC70_RS13670	COG2918	glutathione biosynthetic process
ASALC70_RS13675	COG2183	response to ionizing radiation
ASALC70_RS13715	COG3712	iron ion homeostasis
ASALC70_RS13720	COG1629	transport
ASALC70_RS13720	COG4774	siderophore transport
ASALC70_RS13735	COG0129	dihydroxy-acid dehydratase activity
ASALC70_RS13740	COG0165	Argininosuccinate lyase
ASALC70_RS13745	COG3275	phosphorelay sensor kinase activity
ASALC70_RS13755	COG0181	hydroxymethylbilane synthase activity
ASALC70_RS13785	COG3008	intermembrane lipid transfer
ASALC70_RS13785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASALC70_RS13790	COG2995	paraquat-inducible protein a
ASALC70_RS13800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASALC70_RS13800	COG0543	2 iron, 2 sulfur cluster binding
ASALC70_RS13820	COG0129	dihydroxy-acid dehydratase activity
ASALC70_RS13825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASALC70_RS13825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASALC70_RS13835	COG1392	Phosphate transport regulator
ASALC70_RS13840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASALC70_RS13845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASALC70_RS13865	COG0859	PFAM glycosyl transferase family 9
ASALC70_RS13870	COG0438	transferase activity, transferring glycosyl groups
ASALC70_RS13880	COG1215	transferase activity, transferring glycosyl groups
ASALC70_RS13890	COG3562	capsule polysaccharide
ASALC70_RS13910	COG1560	Kdo2-lipid A biosynthetic process
ASALC70_RS13925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASALC70_RS13925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASALC70_RS13940	COG1051	belongs to the nudix hydrolase family
ASALC70_RS13965	COG0730	response to heat
ASALC70_RS13970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASALC70_RS13975	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASALC70_RS14020	COG3098	single-species biofilm formation
ASALC70_RS14025	COG0546	phosphoglycolate phosphatase activity
ASALC70_RS14030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASALC70_RS14040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASALC70_RS14045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASALC70_RS14050	COG1215	transferase activity, transferring glycosyl groups
ASALC70_RS14070	COG1595	DNA-templated transcription, initiation
ASALC70_RS14075	COG3712	iron ion homeostasis
ASALC70_RS14090	COG2608	mercury ion transmembrane transporter activity
ASALC70_RS14145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASALC70_RS14160	COG2133	pyrroloquinoline quinone binding
ASALC70_RS14165	COG2133	pyrroloquinoline quinone binding
ASALC70_RS14175	COG0625	glutathione transferase activity
ASALC70_RS14185	COG1295	ribonuclease BN
ASALC70_RS14190	COG1252	NADH dehydrogenase
ASALC70_RS14200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASALC70_RS14205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASALC70_RS14210	COG1011	Hydrolase
ASALC70_RS14215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_RS14225	COG0667	Aldo Keto reductase
ASALC70_RS14240	COG1538	Outer membrane efflux protein
ASALC70_RS14245	COG1538	Outer membrane efflux protein
ASALC70_RS14255	COG0494	nUDIX hydrolase
ASALC70_RS14260	COG3151	Protein conserved in bacteria
ASALC70_RS14265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASALC70_RS14270	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASALC70_RS14275	COG3150	esterase
ASALC70_RS14300	COG3122	Protein conserved in bacteria
ASALC70_RS14310	COG2207	Transcriptional regulator
ASALC70_RS14315	COG2366	antibiotic biosynthetic process
ASALC70_RS14320	COG0183	Belongs to the thiolase family
ASALC70_RS14325	COG2267	carboxylic ester hydrolase activity
ASALC70_RS14330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASALC70_RS14335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASALC70_RS14340	COG1509	lysine 2,3-aminomutase activity
ASALC70_RS14355	COG0560	Phosphoserine phosphatase
ASALC70_RS14355	COG3830	Belongs to the UPF0237 family
ASALC70_RS14365	COG1024	Enoyl-CoA hydratase
ASALC70_RS14370	COG0688	phosphatidylethanolamine metabolic process
ASALC70_RS14380	COG1162	GTPase activity
ASALC70_RS14385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASALC70_RS14395	COG3909	cytochrome
ASALC70_RS14410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASALC70_RS14410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASALC70_RS14415	COG0802	atpase or kinase
ASALC70_RS14420	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASALC70_RS14430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASALC70_RS14440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASALC70_RS14445	COG0330	HflC and HflK could
ASALC70_RS14450	COG0330	HflC and HflK could
ASALC70_RS14460	COG2204	response regulator
ASALC70_RS14475	COG0745	RESPONSE REGULATOR receiver
ASALC70_RS14495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASALC70_RS14535	COG0557	exoribonuclease II activity
ASALC70_RS14540	COG0557	exoribonuclease II activity
ASALC70_RS14550	COG0360	Binds together with S18 to 16S ribosomal RNA
ASALC70_RS14560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASALC70_RS14565	COG0359	binds to the 23S rRNA
ASALC70_RS14575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASALC70_RS14580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASALC70_RS14590	COG0569	domain protein
ASALC70_RS14595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_RS14605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_RS14625	COG2203	Gaf domain
ASALC70_RS14625	COG3706	GGDEF domain
ASALC70_RS14625	COG4251	negative regulation of phosphorylation
ASALC70_RS14625	COG5001	Diguanylate cyclase
ASALC70_RS14635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASALC70_RS14655	COG1595	DNA-templated transcription, initiation
ASALC70_RS14660	COG0488	(ABC) transporter
ASALC70_RS14665	COG0840	transmembrane signaling receptor activity
ASALC70_RS14675	COG0840	transmembrane signaling receptor activity
ASALC70_RS14680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASALC70_RS14690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASALC70_RS14715	COG3396	Phenylacetate-CoA oxygenase
ASALC70_RS14720	COG3460	Phenylacetate-CoA oxygenase
ASALC70_RS14725	COG3396	Phenylacetate-CoA oxygenase
ASALC70_RS14730	COG2151	metal-sulfur cluster biosynthetic enzyme
ASALC70_RS14845	COG0456	acetyltransferase
ASALC70_RS14850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ASALC70_RS14855	COG0842	Transport permease protein
ASALC70_RS14860	COG0842	Transport permease protein
ASALC70_RS14860	COG1129	ABC transporter
ASALC70_RS14865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS14870	COG1053	succinate dehydrogenase
ASALC70_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS14890	COG2871	sodium ion transport
ASALC70_RS14895	COG2871	sodium ion transport
ASALC70_RS14900	COG2871	sodium ion transport
ASALC70_RS14905	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_RS14925	COG1805	sodium ion transport
ASALC70_RS14935	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_RS14940	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_RS14945	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_RS14975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_RS14980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_RS15000	COG0737	Belongs to the 5'-nucleotidase family
ASALC70_RS15075	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_RS15100	COG1024	Enoyl-CoA hydratase
ASALC70_RS15110	COG0183	Belongs to the thiolase family
ASALC70_RS15140	COG2226	methyltransferase
ASALC70_RS15155	COG0778	Nitroreductase
ASALC70_RS15165	COG1846	Transcriptional regulator
ASALC70_RS15180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS15185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_RS15200	COG1335	isochorismatase
ASALC70_RS15210	COG0596	Alpha beta hydrolase
ASALC70_RS15265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASALC70_RS15270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASALC70_RS15280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASALC70_RS15285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASALC70_RS15290	COG0142	geranyltranstransferase activity
ASALC70_RS15315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_RS15325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASALC70_RS15335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_RS15345	COG2205	protein histidine kinase activity
ASALC70_RS15355	COG0662	Cupin 2, conserved barrel domain protein
ASALC70_RS15375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_RS15380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS15385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_RS15395	COG1469	GTP cyclohydrolase I activity
ASALC70_RS15425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASALC70_RS15435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASALC70_RS15445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASALC70_RS15450	COG2814	Major facilitator Superfamily
ASALC70_RS15460	COG4251	negative regulation of phosphorylation
ASALC70_RS15460	COG5001	Diguanylate cyclase
ASALC70_RS15460	COG2203	Gaf domain
ASALC70_RS15460	COG3706	GGDEF domain
ASALC70_RS15480	COG0537	adenosine 5'-monophosphoramidase activity
ASALC70_RS15505	COG2267	carboxylic ester hydrolase activity
ASALC70_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS15555	COG2835	tetraacyldisaccharide 4'-kinase activity
ASALC70_RS15560	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS15570	COG2832	Protein of unknown function (DUF454)
ASALC70_RS15575	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS15605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASALC70_RS15615	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_RS15625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASALC70_RS15660	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_RS15665	COG3189	MarR family transcriptional regulator
ASALC70_RS15675	COG2070	2-Nitropropane dioxygenase
ASALC70_RS15695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_RS15700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASALC70_RS15705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASALC70_RS15715	COG0583	DNA-binding transcription factor activity
ASALC70_RS15740	COG5642	Protein of unknown function (DUF2384)
ASALC70_RS15745	COG5654	RES domain protein
ASALC70_RS15770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASALC70_RS15795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASALC70_RS15800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASALC70_RS15805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASALC70_RS15810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASALC70_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS15830	COG0617	tRNA 3'-terminal CCA addition
ASALC70_RS15845	COG3842	ATPase activity
ASALC70_RS15850	COG4149	molybdate abc transporter
ASALC70_RS15860	COG2719	SpoVR family
ASALC70_RS15865	COG2718	Belongs to the UPF0229 family
ASALC70_RS15870	COG2766	serine protein kinase
ASALC70_RS15875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASALC70_RS15880	COG2967	ApaG domain
ASALC70_RS15895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_RS15900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_RS15905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASALC70_RS15910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASALC70_RS15925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASALC70_RS15945	COG0477	Major facilitator Superfamily
ASALC70_RS15955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASALC70_RS15960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_RS15970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASALC70_RS15990	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ASALC70_RS16005	COG0512	Glutamine amidotransferase of anthranilate synthase
ASALC70_RS16010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASALC70_RS16015	COG0134	indole-3-glycerol-phosphate synthase activity
ASALC70_RS16035	COG1765	OsmC-like protein
ASALC70_RS16040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ASALC70_RS16060	COG2205	protein histidine kinase activity
ASALC70_RS16060	COG3437	response regulator, receiver
ASALC70_RS16060	COG3850	Histidine kinase
ASALC70_RS16060	COG4999	Histidine kinase
ASALC70_RS16070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_RS16085	COG0151	Belongs to the GarS family
ASALC70_RS16090	COG0138	bifunctional purine biosynthesis protein purh
ASALC70_RS16150	COG0511	ligase activity, forming carbon-carbon bonds
ASALC70_RS16155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASALC70_RS16175	COG0642	Histidine kinase
ASALC70_RS16185	COG2226	methyltransferase
ASALC70_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS16215	COG1022	Amp-dependent synthetase and ligase
ASALC70_RS16245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASALC70_RS16335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASALC70_RS16340	COG0163	prenyltransferase activity
ASALC70_RS16355	COG0848	biopolymer transport protein
ASALC70_RS16360	COG0811	peptide transport
ASALC70_RS16365	COG3015	lipoprotein NlpE involved in copper resistance
ASALC70_RS16375	COG1595	DNA-templated transcription, initiation
ASALC70_RS16380	COG3712	iron ion homeostasis
ASALC70_RS16385	COG4716	Myosin-crossreactive antigen
ASALC70_RS16460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASALC70_RS16465	COG0321	lipoyl(octanoyl) transferase activity
ASALC70_RS16485	COG1686	Belongs to the peptidase S11 family
ASALC70_RS16495	COG2951	lytic endotransglycosylase activity
ASALC70_RS16500	COG0772	Belongs to the SEDS family
ASALC70_RS16505	COG0768	penicillin binding
ASALC70_RS16510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASALC70_RS16525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASALC70_RS16545	COG0495	leucyl-tRNA aminoacylation
ASALC70_RS16560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_RS16560	COG3453	Protein conserved in bacteria
ASALC70_RS16570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASALC70_RS16575	COG4535	Mg2 and Co2 transporter CorC
ASALC70_RS16585	COG1702	phosphate starvation-inducible protein PhoH
ASALC70_RS16595	COG4208	sulfate ABC transporter
ASALC70_RS16605	COG1595	DNA-templated transcription, initiation
ASALC70_RS16635	COG1999	signal sequence binding
ASALC70_RS16675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_RS16720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_RS16725	COG1278	Cold shock
ASALC70_RS16745	COG0501	Belongs to the peptidase M48B family
ASALC70_RS16750	COG1704	LemA family
ASALC70_RS16755	COG0109	protoheme IX farnesyltransferase activity
ASALC70_RS16760	COG1612	heme a metabolic process
ASALC70_RS16785	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ASALC70_RS16790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_RS16795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASALC70_RS16820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASALC70_RS16845	COG3813	Protein conserved in bacteria
ASALC70_RS16850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASALC70_RS16870	COG4176	ABC-type proline glycine betaine transport system permease component
ASALC70_RS16905	COG3842	ATPase activity
ASALC70_RS16940	COG2827	Endonuclease containing a URI domain
ASALC70_RS16950	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASALC70_RS16960	COG2863	cytochrome
ASALC70_RS16965	COG3258	Cytochrome c
ASALC70_RS16980	COG1104	cysteine desulfurase activity
ASALC70_RS16990	COG2166	iron-sulfur cluster assembly
ASALC70_RS16995	COG2151	metal-sulfur cluster biosynthetic enzyme
ASALC70_RS17000	COG0316	Belongs to the HesB IscA family
ASALC70_RS17005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASALC70_RS17010	COG0719	Fe-S assembly protein
ASALC70_RS17015	COG0396	ATPase activity
ASALC70_RS17025	COG0105	UTP biosynthetic process
ASALC70_RS17030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASALC70_RS17040	COG1426	Protein conserved in bacteria
ASALC70_RS17050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASALC70_RS17055	COG0124	histidyl-tRNA synthetase
ASALC70_RS17065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASALC70_RS17070	COG1160	GTP binding
ASALC70_RS17085	COG0784	Response regulator, receiver
ASALC70_RS17085	COG2205	protein histidine kinase activity
ASALC70_RS17085	COG5002	protein histidine kinase activity
ASALC70_RS17090	COG1570	exodeoxyribonuclease VII activity
ASALC70_RS17120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASALC70_RS17165	COG0653	protein targeting
ASALC70_RS17175	COG3609	addiction module antidote protein, CC2985 family
ASALC70_RS17260	COG1304	FMN binding
ASALC70_RS17285	COG0662	Cupin 2, conserved barrel domain protein
ASALC70_RS17285	COG2207	Transcriptional regulator
ASALC70_RS17310	COG2358	TRAP transporter, solute receptor (TAXI family
ASALC70_RS17325	COG0583	DNA-binding transcription factor activity
ASALC70_RS17330	COG0300	oxidoreductase activity
ASALC70_RS17335	COG2910	NAD(P)H-binding
ASALC70_RS17340	COG1733	regulation of RNA biosynthetic process
ASALC70_RS17380	COG1309	transcriptional regulator
ASALC70_RS17415	COG0789	Transcriptional regulator
ASALC70_RS17420	COG0583	DNA-binding transcription factor activity
ASALC70_RS17425	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS17480	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASALC70_RS17485	COG2944	sequence-specific DNA binding
ASALC70_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS17525	COG3541	Predicted nucleotidyltransferase
ASALC70_RS17545	COG3938	Belongs to the proline racemase family
ASALC70_RS17595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_RS17600	COG1116	anion transmembrane transporter activity
ASALC70_RS17610	COG0657	acetylesterase activity
ASALC70_RS17665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_RS17670	COG1414	Transcriptional regulator
ASALC70_RS17690	COG3971	2-oxopent-4-enoate hydratase activity
ASALC70_RS17720	COG3647	Membrane
ASALC70_RS17735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_RS17735	COG1199	ATP-dependent helicase activity
ASALC70_RS17740	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ASALC70_RS17745	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS17830	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASALC70_RS17840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_RS17845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_RS17860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASALC70_RS17860	COG3323	Protein of unknown function (DUF1653)
ASALC70_RS17885	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASALC70_RS17890	COG4536	flavin adenine dinucleotide binding
ASALC70_RS17935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASALC70_RS17940	COG0228	four-way junction DNA binding
ASALC70_RS17950	COG0336	Belongs to the RNA methyltransferase TrmD family
ASALC70_RS17955	COG0335	large ribosomal subunit rRNA binding
ASALC70_RS17970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASALC70_RS17975	COG0436	Aminotransferase
ASALC70_RS17995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_RS18005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASALC70_RS18020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_RS18025	COG2264	protein methyltransferase activity
ASALC70_RS18030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASALC70_RS18035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_RS18070	COG2373	Large extracellular alpha-helical protein
ASALC70_RS18075	COG4953	penicillin-binding protein 1C
ASALC70_RS18085	COG0702	epimerase
ASALC70_RS18105	COG3547	Transposase (IS116 IS110 IS902 family)
ASALC70_RS18165	COG3264	Mechanosensitive ion channel
ASALC70_RS18165	COG1196	nuclear chromosome segregation
ASALC70_RS18180	COG0709	Synthesizes selenophosphate from selenide and ATP
ASALC70_RS18185	COG3639	organic phosphonate transmembrane transporter activity
ASALC70_RS18195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASALC70_RS18195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASALC70_RS18200	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ASALC70_RS18205	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ASALC70_RS18210	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ASALC70_RS18215	COG2030	dehydratase
ASALC70_RS18220	COG1309	transcriptional regulator
ASALC70_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS18255	COG0183	Belongs to the thiolase family
ASALC70_RS18260	COG1946	Acyl-CoA thioesterase
ASALC70_RS18310	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS18360	COG0642	Histidine kinase
ASALC70_RS18380	COG1115	amino acid carrier protein
ASALC70_RS18385	COG1115	amino acid carrier protein
ASALC70_RS18415	COG0071	Belongs to the small heat shock protein (HSP20) family
ASALC70_RS18420	COG3360	Dodecin
ASALC70_RS18430	COG2353	YceI-like domain
ASALC70_RS18480	COG0175	sulfate reduction
ASALC70_RS18495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS18515	COG0583	DNA-binding transcription factor activity
ASALC70_RS18565	COG0488	(ABC) transporter
ASALC70_RS18590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASALC70_RS18600	COG2807	transmembrane transport
ASALC70_RS18615	COG1136	(ABC) transporter
ASALC70_RS18615	COG0577	efflux transmembrane transporter activity
ASALC70_RS18645	COG2856	Zn peptidase
ASALC70_RS18660	COG0183	Belongs to the thiolase family
ASALC70_RS18670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASALC70_RS18690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASALC70_RS18700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASALC70_RS18705	COG1024	Enoyl-CoA hydratase
ASALC70_RS18705	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_RS18765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_RS18785	COG0571	ribonuclease III activity
ASALC70_RS18795	COG1381	Involved in DNA repair and RecF pathway recombination
ASALC70_RS18805	COG0784	Response regulator, receiver
ASALC70_RS18805	COG2205	protein histidine kinase activity
ASALC70_RS18805	COG5002	protein histidine kinase activity
ASALC70_RS18820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASALC70_RS18850	COG0789	Transcriptional regulator
ASALC70_RS18855	COG3328	transposase activity
ASALC70_RS18865	COG3344	reverse transcriptase
ASALC70_RS18885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASALC70_RS18895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASALC70_RS18910	COG0563	adenylate kinase activity
ASALC70_RS18915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASALC70_RS18955	COG1999	signal sequence binding
ASALC70_RS18960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASALC70_RS18965	COG0583	DNA-binding transcription factor activity
ASALC70_RS18985	COG4133	protoheme IX ABC transporter activity
ASALC70_RS19005	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASALC70_RS19055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASALC70_RS19090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASALC70_RS19100	COG1131	(ABC) transporter
ASALC70_RS19105	COG0842	Transport permease protein
ASALC70_RS19110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASALC70_RS19110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASALC70_RS19120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASALC70_RS19130	COG0778	Nitroreductase
ASALC70_RS19180	COG0530	calcium, potassium:sodium antiporter activity
ASALC70_RS19190	COG2267	carboxylic ester hydrolase activity
ASALC70_RS19195	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS19215	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_RS19240	COG0683	leucine binding
ASALC70_RS19245	COG0531	amino acid
ASALC70_RS19250	COG0531	amino acid
ASALC70_RS19255	COG1982	Orn Lys Arg decarboxylase major
ASALC70_RS19260	COG1982	Orn Lys Arg decarboxylase major
ASALC70_RS19265	COG0183	Belongs to the thiolase family
ASALC70_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS19280	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19285	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19290	COG1309	transcriptional regulator
ASALC70_RS19295	COG1024	Enoyl-CoA hydratase
ASALC70_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS19320	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS19340	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS19365	COG2205	protein histidine kinase activity
ASALC70_RS19365	COG0784	Response regulator, receiver
ASALC70_RS19425	COG4772	TonB-dependent receptor
ASALC70_RS19435	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS19450	COG3284	Transcriptional regulator
ASALC70_RS19455	COG3284	Transcriptional regulator
ASALC70_RS19475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_RS19480	COG1309	transcriptional regulator
ASALC70_RS19485	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19505	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS19510	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_RS19535	COG1024	Enoyl-CoA hydratase
ASALC70_RS19535	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_RS19550	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19555	COG2130	NADP-dependent
ASALC70_RS19560	COG2814	Major facilitator Superfamily
ASALC70_RS19565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASALC70_RS19570	COG4774	siderophore transport
ASALC70_RS19595	COG0235	Class ii aldolase
ASALC70_RS19610	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19625	COG1764	response to oxidative stress
ASALC70_RS19650	COG0513	Belongs to the DEAD box helicase family
ASALC70_RS19675	COG3115	cell septum assembly
ASALC70_RS19700	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ASALC70_RS19710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASALC70_RS19710	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ASALC70_RS19775	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS19785	COG1024	Enoyl-CoA hydratase
ASALC70_RS19790	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS19800	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS19810	COG1309	transcriptional regulator
ASALC70_RS19835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_RS19850	COG0308	aminopeptidase N
ASALC70_RS19860	COG3130	regulation of translation
ASALC70_RS19885	COG0471	metal ion transport
ASALC70_RS19885	COG3273	potassium ion transport
ASALC70_RS19990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASALC70_RS20000	COG3206	protein involved in exopolysaccharide biosynthesis
ASALC70_RS20000	COG0489	protein tyrosine kinase activity
ASALC70_RS20010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASALC70_RS20015	COG2433	Pfam Transposase IS66
ASALC70_RS20025	COG2963	transposase activity
ASALC70_RS20085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASALC70_RS20090	COG0110	maltose O-acetyltransferase activity
ASALC70_RS20115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASALC70_RS20135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASALC70_RS20150	COG3307	-O-antigen
ASALC70_RS20200	COG0457	Tetratricopeptide repeat
ASALC70_RS20210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ASALC70_RS20235	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS20245	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASALC70_RS20255	COG0588	phosphoglycerate mutase activity
ASALC70_RS20265	COG3100	YcgL domain-containing protein
ASALC70_RS20270	COG2983	Belongs to the UPF0260 family
ASALC70_RS20280	COG0537	adenosine 5'-monophosphoramidase activity
ASALC70_RS20315	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_RS20350	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS20355	COG0546	phosphoglycolate phosphatase activity
ASALC70_RS20360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASALC70_RS20365	COG0402	S-adenosylhomocysteine deaminase activity
ASALC70_RS20375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASALC70_RS20380	COG1605	Chorismate mutase
ASALC70_RS20380	COG0077	Prephenate dehydratase
ASALC70_RS20395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASALC70_RS20405	COG0776	regulation of translation
ASALC70_RS20415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASALC70_RS20420	COG0284	orotidine-5'-phosphate decarboxylase activity
ASALC70_RS20435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASALC70_RS20450	COG4659	FMN binding
ASALC70_RS20455	COG4658	electron transport chain
ASALC70_RS20460	COG4656	Part of a membrane complex involved in electron transport
ASALC70_RS20465	COG2878	Part of a membrane complex involved in electron transport
ASALC70_RS20500	COG0784	Response regulator, receiver
ASALC70_RS20500	COG2205	protein histidine kinase activity
ASALC70_RS20500	COG5002	protein histidine kinase activity
ASALC70_RS20505	COG3540	Alkaline phosphatase
ASALC70_RS20545	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ASALC70_RS20555	COG0501	Belongs to the peptidase M48B family
ASALC70_RS20560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASALC70_RS20570	COG0436	Aminotransferase
ASALC70_RS20580	COG0672	)-iron permease
ASALC70_RS20620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASALC70_RS20625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASALC70_RS20635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASALC70_RS20645	COG5002	protein histidine kinase activity
ASALC70_RS20645	COG2198	Histidine kinase
ASALC70_RS20645	COG0784	Response regulator, receiver
ASALC70_RS20675	COG0163	prenyltransferase activity
ASALC70_RS20680	COG0583	DNA-binding transcription factor activity
ASALC70_RS20685	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_RS20690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASALC70_RS20695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_RS20735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_RS20745	COG1024	Enoyl-CoA hydratase
ASALC70_RS20815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_RS20835	COG2885	chlorophyll binding
ASALC70_RS20845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_RS20875	COG3220	belongs to the UPF0276 family
ASALC70_RS20890	COG2853	Lipoprotein
ASALC70_RS20900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASALC70_RS20905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASALC70_RS20915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_RS20940	COG5642	Protein of unknown function (DUF2384)
ASALC70_RS20975	COG2009	succinate dehydrogenase
ASALC70_RS20980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASALC70_RS21010	COG0045	succinate-CoA ligase (ADP-forming) activity
ASALC70_RS21015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASALC70_RS21035	COG1090	epimerase
ASALC70_RS21040	COG1090	epimerase
ASALC70_RS21050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASALC70_RS21055	COG2062	phosphohistidine phosphatase, SixA
ASALC70_RS21065	COG0708	Exodeoxyribonuclease III
ASALC70_RS21080	COG2267	carboxylic ester hydrolase activity
ASALC70_RS21090	COG3268	Saccharopine dehydrogenase
ASALC70_RS21105	COG1301	dicarboxylic acid transport
ASALC70_RS21110	COG1301	dicarboxylic acid transport
ASALC70_RS21120	COG0004	ammonium transporteR
ASALC70_RS21135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASALC70_RS21140	COG2814	Major facilitator Superfamily
ASALC70_RS21145	COG0488	(ABC) transporter
ASALC70_RS21160	COG0066	3-isopropylmalate dehydratase activity
ASALC70_RS21165	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_RS21175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASALC70_RS21190	COG0101	tRNA pseudouridine synthase activity
ASALC70_RS21195	COG0135	phosphoribosylanthranilate isomerase activity
ASALC70_RS21205	COG0159	tryptophan synthase activity
ASALC70_RS21215	COG0285	dihydrofolate synthase activity
ASALC70_RS21230	COG1286	toxin biosynthetic process
ASALC70_RS21245	COG0714	Associated with various cellular activities
ASALC70_RS21340	COG0789	Transcriptional regulator
ASALC70_RS21350	COG5001	Diguanylate cyclase
ASALC70_RS21350	COG3706	GGDEF domain
ASALC70_RS21350	COG2203	Gaf domain
ASALC70_RS21350	COG4251	negative regulation of phosphorylation
ASALC70_RS21355	COG1643	Atp-dependent helicase
ASALC70_RS21390	COG3228	Belongs to the MtfA family
ASALC70_RS21405	COG0484	heat shock protein binding
ASALC70_RS21415	COG0438	transferase activity, transferring glycosyl groups
ASALC70_RS21475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_RS21490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASALC70_RS21495	COG1960	acyl-CoA dehydrogenase activity
ASALC70_RS21505	COG0784	Response regulator, receiver
ASALC70_RS21505	COG5002	protein histidine kinase activity
ASALC70_RS21515	COG0702	epimerase
ASALC70_RS21525	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASALC70_RS21540	COG3416	Protein conserved in bacteria
ASALC70_RS21540	COG2943	transferase activity, transferring hexosyl groups
ASALC70_RS21550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASALC70_RS21550	COG3620	sequence-specific DNA binding
ASALC70_RS21550	COG0617	tRNA 3'-terminal CCA addition
ASALC70_RS21560	COG0039	L-malate dehydrogenase activity
ASALC70_RS21565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS21580	COG2272	Belongs to the type-B carboxylesterase lipase family
ASALC70_RS21585	COG0271	Belongs to the BolA IbaG family
ASALC70_RS21590	COG1054	Belongs to the UPF0176 family
ASALC70_RS21605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASALC70_RS21630	COG0300	oxidoreductase activity
ASALC70_RS21635	COG0037	tRNA processing
ASALC70_RS21640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASALC70_RS21650	COG1309	transcriptional regulator
ASALC70_RS21655	COG1335	isochorismatase
ASALC70_RS21660	COG0596	Alpha beta hydrolase
ASALC70_RS21665	COG3473	Maleate cis-trans isomerase
ASALC70_RS21670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_RS21700	COG0683	leucine binding
ASALC70_RS21735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASALC70_RS21745	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ASALC70_RS21760	COG2850	peptidyl-arginine hydroxylation
ASALC70_RS21770	COG2915	High frequency lysogenization protein hflD homolog
ASALC70_RS21775	COG0482	sulfurtransferase activity
ASALC70_RS21785	COG0315	cyclic pyranopterin monophosphate synthase activity
ASALC70_RS21795	COG0314	molybdopterin synthase activity
ASALC70_RS21810	COG1278	Cold shock
ASALC70_RS21825	COG3344	reverse transcriptase
ASALC70_RS21845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASALC70_RS21855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_RS21870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASALC70_RS21880	COG1674	ftsk spoiiie
ASALC70_RS21885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASALC70_RS21890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASALC70_RS21895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASALC70_RS21910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASALC70_RS21910	COG1648	precorrin-2 dehydrogenase activity
ASALC70_RS21925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASALC70_RS21940	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASALC70_RS21970	COG0583	DNA-binding transcription factor activity
ASALC70_RS21985	COG0003	Pfam Anion-transporting ATPase
ASALC70_RS21995	COG1966	Carbon starvation protein
ASALC70_RS22005	COG0322	excinuclease ABC activity
ASALC70_RS22010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASALC70_RS22030	COG0784	Response regulator, receiver
ASALC70_RS22030	COG5002	protein histidine kinase activity
ASALC70_RS22035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_RS22050	COG3437	response regulator, receiver