locus-tag	class	description
GQR98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQR98_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GQR98_RS00030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQR98_RS00040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GQR98_RS00045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQR98_RS00060	COG0336	Belongs to the RNA methyltransferase TrmD family
GQR98_RS00070	COG0335	large ribosomal subunit rRNA binding
GQR98_RS00075	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS00085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQR98_RS00090	COG1085	galactose-1-phosphate uridylyltransferase
GQR98_RS00105	COG0124	histidyl-tRNA synthetase
GQR98_RS00125	COG0359	binds to the 23S rRNA
GQR98_RS00130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GQR98_RS00135	COG0360	Binds together with S18 to 16S ribosomal RNA
GQR98_RS00140	COG3279	Response regulator of the LytR AlgR family
GQR98_RS00145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQR98_RS00165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GQR98_RS00175	COG3279	Response regulator of the LytR AlgR family
GQR98_RS00185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQR98_RS00200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQR98_RS00210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQR98_RS00230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GQR98_RS00240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GQR98_RS00245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQR98_RS00250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQR98_RS00265	COG3956	TIGRFAM MazG family protein
GQR98_RS00300	COG0714	Associated with various cellular activities
GQR98_RS00305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQR98_RS00315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQR98_RS00330	COG1131	(ABC) transporter
GQR98_RS00355	COG0156	8-amino-7-oxononanoate synthase activity
GQR98_RS00360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR98_RS00365	COG1522	sequence-specific DNA binding
GQR98_RS00385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQR98_RS00390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQR98_RS00405	COG2204	response regulator
GQR98_RS00410	COG5002	protein histidine kinase activity
GQR98_RS00415	COG0492	ferredoxin-NADP+ reductase activity
GQR98_RS00425	COG0247	lactate metabolic process
GQR98_RS00430	COG1139	Iron-sulfur cluster binding protein
GQR98_RS00435	COG1556	Lactate utilization protein
GQR98_RS00465	COG2801	Transposase and inactivated derivatives
GQR98_RS00515	COG3254	rhamnose metabolic process
GQR98_RS00520	COG0738	Major facilitator superfamily
GQR98_RS00525	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS00530	COG3618	amidohydrolase
GQR98_RS00535	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQR98_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS00545	COG2721	sulfolactate sulfo-lyase activity
GQR98_RS00550	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS00605	COG3119	arylsulfatase activity
GQR98_RS00625	COG3119	arylsulfatase activity
GQR98_RS00635	COG3119	arylsulfatase activity
GQR98_RS00655	COG1501	Belongs to the glycosyl hydrolase 31 family
GQR98_RS00665	COG3119	arylsulfatase activity
GQR98_RS00680	COG0284	orotidine-5'-phosphate decarboxylase activity
GQR98_RS00685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQR98_RS00690	COG1137	ATPase activity
GQR98_RS00710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQR98_RS00720	COG0174	glutamine synthetase
GQR98_RS00810	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GQR98_RS00815	COG0732	type I restriction modification DNA specificity domain
GQR98_RS00825	COG1401	restriction endodeoxyribonuclease activity
GQR98_RS00835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQR98_RS00860	COG0730	response to heat
GQR98_RS00865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQR98_RS00865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQR98_RS00880	COG2972	Histidine kinase
GQR98_RS00880	COG0745	RESPONSE REGULATOR receiver
GQR98_RS00890	COG2264	protein methyltransferase activity
GQR98_RS00895	COG0149	triose-phosphate isomerase activity
GQR98_RS00900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQR98_RS00920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQR98_RS00930	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GQR98_RS00940	COG1132	(ABC) transporter
GQR98_RS00945	COG0101	tRNA pseudouridine synthase activity
GQR98_RS00985	COG0268	Binds directly to 16S ribosomal RNA
GQR98_RS00995	COG0442	prolyl-tRNA aminoacylation
GQR98_RS01010	COG0302	gtp cyclohydrolase
GQR98_RS01015	COG0215	cysteine-tRNA ligase activity
GQR98_RS01020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GQR98_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS01045	COG1733	regulation of RNA biosynthetic process
GQR98_RS01085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQR98_RS01090	COG1127	ABC transporter
GQR98_RS01110	COG2308	Evidence 4 Homologs of previously reported genes of
GQR98_RS01120	COG1305	Transglutaminase-like
GQR98_RS01130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GQR98_RS01135	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GQR98_RS01140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GQR98_RS01160	COG1988	membrane-bound metal-dependent
GQR98_RS01165	COG1490	D-aminoacyl-tRNA deacylase activity
GQR98_RS01170	COG1162	GTPase activity
GQR98_RS01180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GQR98_RS01185	COG0287	Prephenate dehydrogenase
GQR98_RS01190	COG0436	Aminotransferase
GQR98_RS01195	COG0077	Prephenate dehydratase
GQR98_RS01195	COG1605	Chorismate mutase
GQR98_RS01205	COG0857	belongs to the CobB CobQ family
GQR98_RS01205	COG0280	phosphate acetyltransferase
GQR98_RS01210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GQR98_RS01225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GQR98_RS01240	COG2329	Antibiotic biosynthesis monooxygenase
GQR98_RS01245	COG1410	methionine synthase
GQR98_RS01245	COG0646	methionine synthase
GQR98_RS01255	COG1045	serine acetyltransferase
GQR98_RS01260	COG0492	ferredoxin-NADP+ reductase activity
GQR98_RS01265	COG1648	precorrin-2 dehydrogenase activity
GQR98_RS01265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQR98_RS01270	COG1648	precorrin-2 dehydrogenase activity
GQR98_RS01270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GQR98_RS01275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR98_RS01280	COG2895	sulfate adenylyltransferase (ATP) activity
GQR98_RS01285	COG0175	sulfate reduction
GQR98_RS01300	COG1959	2 iron, 2 sulfur cluster binding
GQR98_RS01310	COG2274	protein secretion by the type I secretion system
GQR98_RS01370	COG0460	homoserine dehydrogenase
GQR98_RS01370	COG0527	aspartate kinase activity
GQR98_RS01385	COG0514	ATP-dependent DNA helicase (RecQ)
GQR98_RS01390	COG0517	IMP dehydrogenase activity
GQR98_RS01390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQR98_RS01395	COG0805	protein transport
GQR98_RS01405	COG1137	ATPase activity
GQR98_RS01415	COG1253	flavin adenine dinucleotide binding
GQR98_RS01420	COG1183	phosphatidylcholine synthase activity
GQR98_RS01435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQR98_RS01440	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS01450	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS01500	COG2089	acid synthase
GQR98_RS01505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GQR98_RS01535	COG0463	Glycosyl transferase, family 2
GQR98_RS01555	COG1216	Glycosyl transferase, family 2
GQR98_RS01560	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS01565	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS01570	COG0463	Glycosyl transferase, family 2
GQR98_RS01590	COG0489	protein tyrosine kinase activity
GQR98_RS01600	COG0488	(ABC) transporter
GQR98_RS01615	COG2814	Major facilitator Superfamily
GQR98_RS01625	COG1522	sequence-specific DNA binding
GQR98_RS01640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQR98_RS01645	COG0045	succinate-CoA ligase (ADP-forming) activity
GQR98_RS01680	COG2326	polyphosphate kinase activity
GQR98_RS01700	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS01705	COG0561	phosphatase activity
GQR98_RS01730	COG0745	RESPONSE REGULATOR receiver
GQR98_RS01735	COG2205	protein histidine kinase activity
GQR98_RS01735	COG4999	Histidine kinase
GQR98_RS01735	COG3437	response regulator, receiver
GQR98_RS01735	COG3850	Histidine kinase
GQR98_RS01740	COG2217	Heavy metal translocating P-type atpase
GQR98_RS01750	COG3278	Belongs to the heme-copper respiratory oxidase family
GQR98_RS01760	COG2010	Cytochrome c
GQR98_RS01765	COG0348	domain, Protein
GQR98_RS01780	COG0589	response to stress
GQR98_RS01785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQR98_RS01805	COG4206	TonB-dependent receptor
GQR98_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS01875	COG4974	Belongs to the 'phage' integrase family
GQR98_RS01935	COG2801	Transposase and inactivated derivatives
GQR98_RS01960	COG2217	Heavy metal translocating P-type atpase
GQR98_RS01975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQR98_RS01980	COG2356	endonuclease I
GQR98_RS02075	COG2801	Transposase and inactivated derivatives
GQR98_RS02135	COG0488	(ABC) transporter
GQR98_RS02145	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GQR98_RS02145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR98_RS02165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQR98_RS02210	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQR98_RS02215	COG0459	protein refolding
GQR98_RS02245	COG1629	transport
GQR98_RS02245	COG4206	TonB-dependent receptor
GQR98_RS02260	COG1482	cell wall glycoprotein biosynthetic process
GQR98_RS02265	COG1609	Transcriptional regulator
GQR98_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS02285	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS02310	COG0657	acetylesterase activity
GQR98_RS02310	COG2755	lipolytic protein G-D-S-L family
GQR98_RS02315	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS02330	COG3537	Alpha-1,2-mannosidase
GQR98_RS02340	COG0561	phosphatase activity
GQR98_RS02345	COG4206	TonB-dependent receptor
GQR98_RS02345	COG1629	transport
GQR98_RS02355	COG0673	inositol 2-dehydrogenase activity
GQR98_RS02360	COG0673	inositol 2-dehydrogenase activity
GQR98_RS02440	COG4106	trans-aconitate 2-methyltransferase activity
GQR98_RS02475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GQR98_RS02480	COG0471	metal ion transport
GQR98_RS02480	COG0490	domain, Protein
GQR98_RS02485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GQR98_RS02495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQR98_RS02520	COG3340	Belongs to the peptidase S51 family
GQR98_RS02535	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GQR98_RS02540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR98_RS02545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GQR98_RS02555	COG0110	maltose O-acetyltransferase activity
GQR98_RS02575	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS02585	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS02600	COG0463	Glycosyl transferase, family 2
GQR98_RS02605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR98_RS02615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQR98_RS02650	COG2133	pyrroloquinoline quinone binding
GQR98_RS02655	COG2010	Cytochrome c
GQR98_RS02660	COG0572	uridine kinase
GQR98_RS02670	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQR98_RS02680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQR98_RS02680	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQR98_RS02685	COG4628	conserved protein (DUF2132)
GQR98_RS02695	COG0513	Belongs to the DEAD box helicase family
GQR98_RS02700	COG0308	aminopeptidase N
GQR98_RS02710	COG4585	Histidine kinase
GQR98_RS02715	COG2197	response regulator
GQR98_RS02750	COG0514	ATP-dependent DNA helicase (RecQ)
GQR98_RS02760	COG0494	nUDIX hydrolase
GQR98_RS02765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQR98_RS02800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQR98_RS02810	COG2885	chlorophyll binding
GQR98_RS02830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQR98_RS02835	COG0085	RNA polymerase activity
GQR98_RS02840	COG0222	ribosome binding
GQR98_RS02845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQR98_RS02850	COG0081	regulation of translation
GQR98_RS02855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQR98_RS02875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQR98_RS02900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GQR98_RS02905	COG4974	Belongs to the 'phage' integrase family
GQR98_RS02910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQR98_RS02915	COG1960	acyl-CoA dehydrogenase activity
GQR98_RS02925	COG1115	amino acid carrier protein
GQR98_RS02930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQR98_RS02950	COG0577	efflux transmembrane transporter activity
GQR98_RS02955	COG3876	Protein conserved in bacteria
GQR98_RS02990	COG2884	Cell division ATP-binding protein ftsE
GQR98_RS03000	COG1216	Glycosyl transferase, family 2
GQR98_RS03000	COG1442	glycosyl transferase family 8
GQR98_RS03015	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS03020	COG1216	Glycosyl transferase, family 2
GQR98_RS03025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQR98_RS03045	COG2244	polysaccharide biosynthetic process
GQR98_RS03065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GQR98_RS03095	COG4452	Inner membrane protein CreD
GQR98_RS03115	COG0300	oxidoreductase activity
GQR98_RS03145	COG1629	transport
GQR98_RS03145	COG4206	TonB-dependent receptor
GQR98_RS03160	COG3279	Response regulator of the LytR AlgR family
GQR98_RS03165	COG2226	methyltransferase
GQR98_RS03170	COG0612	Peptidase, M16
GQR98_RS03180	COG4206	TonB-dependent receptor
GQR98_RS03180	COG1629	transport
GQR98_RS03230	COG3119	arylsulfatase activity
GQR98_RS03255	COG3507	Belongs to the glycosyl hydrolase 43 family
GQR98_RS03265	COG4948	Mandelate Racemase Muconate Lactonizing
GQR98_RS03270	COG3119	arylsulfatase activity
GQR98_RS03280	COG3119	arylsulfatase activity
GQR98_RS03285	COG3119	arylsulfatase activity
GQR98_RS03290	COG4206	TonB-dependent receptor
GQR98_RS03290	COG1629	transport
GQR98_RS03325	COG4585	Histidine kinase
GQR98_RS03350	COG2115	Belongs to the xylose isomerase family
GQR98_RS03355	COG1070	Carbohydrate kinase
GQR98_RS03375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQR98_RS03385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQR98_RS03395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQR98_RS03405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GQR98_RS03410	COG0134	indole-3-glycerol-phosphate synthase activity
GQR98_RS03415	COG0133	tryptophan synthase activity
GQR98_RS03420	COG0159	tryptophan synthase activity
GQR98_RS03430	COG1252	NADH dehydrogenase
GQR98_RS03445	COG1192	Involved in chromosome partitioning
GQR98_RS03450	COG1475	DNA binding
GQR98_RS03460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQR98_RS03465	COG0681	Belongs to the peptidase S26 family
GQR98_RS03470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQR98_RS03505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GQR98_RS03520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GQR98_RS03530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQR98_RS03545	COG1278	Cold shock
GQR98_RS03550	COG0105	UTP biosynthetic process
GQR98_RS03560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GQR98_RS03570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQR98_RS03575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQR98_RS03590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQR98_RS03600	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GQR98_RS03600	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GQR98_RS03605	COG0799	negative regulation of ribosome biogenesis
GQR98_RS03610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQR98_RS03620	COG4589	Belongs to the CDS family
GQR98_RS03625	COG0688	phosphatidylethanolamine metabolic process
GQR98_RS03635	COG0525	valine-tRNA ligase activity
GQR98_RS03655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQR98_RS03660	COG1595	DNA-templated transcription, initiation
GQR98_RS03670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQR98_RS03690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQR98_RS03695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQR98_RS03700	COG0784	Response regulator, receiver
GQR98_RS03700	COG2205	protein histidine kinase activity
GQR98_RS03705	COG1663	tetraacyldisaccharide 4'-kinase activity
GQR98_RS03710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQR98_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS03740	COG2267	carboxylic ester hydrolase activity
GQR98_RS03745	COG0596	Alpha beta hydrolase
GQR98_RS03765	COG3844	kynureninase activity
GQR98_RS03770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQR98_RS03800	COG1272	protein, Hemolysin III
GQR98_RS03810	COG1363	Peptidase, m42
GQR98_RS03815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQR98_RS03820	COG2339	peptidase activity
GQR98_RS03825	COG0511	ligase activity, forming carbon-carbon bonds
GQR98_RS03830	COG0439	Biotin carboxylase
GQR98_RS03835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQR98_RS03840	COG0513	Belongs to the DEAD box helicase family
GQR98_RS03855	COG2814	Major facilitator Superfamily
GQR98_RS03865	COG0154	amidase activity
GQR98_RS03870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQR98_RS03890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR98_RS03900	COG2217	Heavy metal translocating P-type atpase
GQR98_RS03910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR98_RS03925	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GQR98_RS03950	COG1253	flavin adenine dinucleotide binding
GQR98_RS03965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GQR98_RS03975	COG0433	COG0433 Predicted ATPase
GQR98_RS03990	COG0602	queuosine metabolic process
GQR98_RS04045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GQR98_RS04050	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQR98_RS04055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQR98_RS04105	COG1233	COG1233 Phytoene dehydrogenase and related
GQR98_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS04160	COG0415	Belongs to the DNA photolyase family
GQR98_RS04165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQR98_RS04200	COG1160	GTP binding
GQR98_RS04210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQR98_RS04240	COG1428	Deoxynucleoside kinase
GQR98_RS04250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GQR98_RS04255	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQR98_RS04265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQR98_RS04270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQR98_RS04275	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GQR98_RS04280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GQR98_RS04285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQR98_RS04290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GQR98_RS04295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GQR98_RS04305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GQR98_RS04310	COG2086	electron transfer activity
GQR98_RS04335	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR98_RS04335	COG0022	dehydrogenase e1 component
GQR98_RS04370	COG3279	Response regulator of the LytR AlgR family
GQR98_RS04385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQR98_RS04410	COG1428	Deoxynucleoside kinase
GQR98_RS04460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQR98_RS04460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQR98_RS04465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQR98_RS04475	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS04480	COG2081	HI0933 family
GQR98_RS04500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQR98_RS04510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GQR98_RS04520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQR98_RS04530	COG4771	TonB-dependent receptor
GQR98_RS04545	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS04555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQR98_RS04560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQR98_RS04575	COG0697	spore germination
GQR98_RS04590	COG4206	TonB-dependent receptor
GQR98_RS04590	COG1629	transport
GQR98_RS04605	COG1858	cytochrome C peroxidase
GQR98_RS04635	COG1408	metallophosphoesterase
GQR98_RS04640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQR98_RS04640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQR98_RS04700	COG1032	radical SAM domain protein
GQR98_RS04715	COG0488	(ABC) transporter
GQR98_RS04725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQR98_RS04730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQR98_RS04735	COG0052	Belongs to the universal ribosomal protein uS2 family
GQR98_RS04740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQR98_RS04745	COG0528	UMP kinase activity
GQR98_RS04750	COG0233	cytoplasmic translational termination
GQR98_RS04765	COG0017	Asparaginyl-tRNA synthetase
GQR98_RS04790	COG0848	biopolymer transport protein
GQR98_RS04800	COG0811	peptide transport
GQR98_RS04810	COG0252	asparaginase activity
GQR98_RS04815	COG0084	hydrolase, TatD family'
GQR98_RS04855	COG2197	response regulator
GQR98_RS04860	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR98_RS04900	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GQR98_RS04920	COG1309	transcriptional regulator
GQR98_RS04935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQR98_RS04940	COG4206	TonB-dependent receptor
GQR98_RS04940	COG1629	transport
GQR98_RS04945	COG4206	TonB-dependent receptor
GQR98_RS04945	COG1629	transport
GQR98_RS04950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQR98_RS04975	COG0667	Aldo Keto reductase
GQR98_RS04995	COG1530	ribonuclease E activity
GQR98_RS05000	COG0776	regulation of translation
GQR98_RS05010	COG0629	single-stranded DNA binding
GQR98_RS05035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQR98_RS05040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQR98_RS05075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQR98_RS05080	COG0463	Glycosyl transferase, family 2
GQR98_RS05095	COG0793	Belongs to the peptidase S41A family
GQR98_RS05115	COG3590	peptidase
GQR98_RS05190	COG0629	single-stranded DNA binding
GQR98_RS05195	COG2205	protein histidine kinase activity
GQR98_RS05195	COG0784	Response regulator, receiver
GQR98_RS05200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQR98_RS05220	COG0004	ammonium transporteR
GQR98_RS05230	COG0004	ammonium transporteR
GQR98_RS05240	COG0070	glutamate synthase
GQR98_RS05240	COG0067	glutamate synthase
GQR98_RS05240	COG0069	glutamate synthase activity
GQR98_RS05250	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQR98_RS05260	COG0527	aspartate kinase activity
GQR98_RS05280	COG0346	lactoylglutathione lyase activity
GQR98_RS05290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQR98_RS05295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQR98_RS05305	COG1629	transport
GQR98_RS05305	COG4206	TonB-dependent receptor
GQR98_RS05330	COG3123	guanosine phosphorylase activity
GQR98_RS05335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQR98_RS05340	COG1053	succinate dehydrogenase
GQR98_RS05355	COG0006	proline dipeptidase activity
GQR98_RS05365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQR98_RS05370	COG0194	GDP metabolic process
GQR98_RS05375	COG1561	YicC-like family, N-terminal region
GQR98_RS05380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQR98_RS05385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQR98_RS05395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GQR98_RS05420	COG1309	transcriptional regulator
GQR98_RS05430	COG2183	response to ionizing radiation
GQR98_RS05435	COG1652	LysM domain
GQR98_RS05445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQR98_RS05470	COG2885	chlorophyll binding
GQR98_RS05470	COG3047	cAMP biosynthetic process
GQR98_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS05485	COG0288	reversible hydration of carbon dioxide
GQR98_RS05490	COG0659	secondary active sulfate transmembrane transporter activity
GQR98_RS05535	COG2304	oxidoreductase activity
GQR98_RS05540	COG2304	oxidoreductase activity
GQR98_RS05555	COG0714	Associated with various cellular activities
GQR98_RS05560	COG4221	oxidoreductase activity
GQR98_RS05585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GQR98_RS05595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQR98_RS05600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQR98_RS05605	COG0511	ligase activity, forming carbon-carbon bonds
GQR98_RS05610	COG0439	Biotin carboxylase
GQR98_RS05620	COG1011	Hydrolase
GQR98_RS05630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQR98_RS05630	COG0758	DNA mediated transformation
GQR98_RS05640	COG1607	acyl-coa hydrolase
GQR98_RS05660	COG4953	penicillin-binding protein 1C
GQR98_RS05675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQR98_RS05685	COG0196	riboflavin kinase activity
GQR98_RS05690	COG2234	aminopeptidase activity
GQR98_RS05690	COG4935	Belongs to the peptidase S8 family
GQR98_RS05695	COG0193	aminoacyl-tRNA hydrolase activity
GQR98_RS05700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GQR98_RS05705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQR98_RS05720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQR98_RS05740	COG2268	Band 7 protein
GQR98_RS05755	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQR98_RS05775	COG4251	negative regulation of phosphorylation
GQR98_RS05785	COG2201	protein-glutamate methylesterase activity
GQR98_RS05790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQR98_RS05800	COG0792	nuclease activity
GQR98_RS05805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQR98_RS05810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQR98_RS05815	COG1121	(ABC) transporter
GQR98_RS05825	COG0803	Belongs to the bacterial solute-binding protein 9 family
GQR98_RS05830	COG4771	TonB-dependent receptor
GQR98_RS05865	COG1999	signal sequence binding
GQR98_RS05870	COG0750	zinc metalloprotease
GQR98_RS05880	COG4974	Belongs to the 'phage' integrase family
GQR98_RS05935	COG0346	lactoylglutathione lyase activity
GQR98_RS05940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQR98_RS05945	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQR98_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS05965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQR98_RS05985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQR98_RS06065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQR98_RS06075	COG1595	DNA-templated transcription, initiation
GQR98_RS06090	COG0180	Tryptophanyl-tRNA synthetase
GQR98_RS06100	COG1505	serine-type exopeptidase activity
GQR98_RS06105	COG2234	aminopeptidase activity
GQR98_RS06110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQR98_RS06115	COG1970	mechanosensitive ion channel activity
GQR98_RS06120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQR98_RS06125	COG1435	thymidine kinase activity
GQR98_RS06135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GQR98_RS06145	COG4948	Mandelate Racemase Muconate Lactonizing
GQR98_RS06150	COG0156	8-amino-7-oxononanoate synthase activity
GQR98_RS06160	COG1629	transport
GQR98_RS06160	COG4206	TonB-dependent receptor
GQR98_RS06170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQR98_RS06170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GQR98_RS06180	COG0481	GTPase activity
GQR98_RS06200	COG3275	phosphorelay sensor kinase activity
GQR98_RS06210	COG0297	glycogen (starch) synthase activity
GQR98_RS06215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GQR98_RS06220	COG0366	Alpha amylase catalytic
GQR98_RS06225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GQR98_RS06240	COG3263	regulation of cellular component size
GQR98_RS06255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQR98_RS06260	COG1404	Belongs to the peptidase S8 family
GQR98_RS06285	COG0594	ribonuclease P activity
GQR98_RS06290	COG0793	Belongs to the peptidase S41A family
GQR98_RS06305	COG2153	protein acetylation
GQR98_RS06315	COG0698	ribose 5-phosphate isomerase
GQR98_RS06320	COG0557	exoribonuclease II activity
GQR98_RS06325	COG1595	DNA-templated transcription, initiation
GQR98_RS06330	COG0393	Putative heavy-metal-binding
GQR98_RS06340	COG0784	Response regulator, receiver
GQR98_RS06340	COG2205	protein histidine kinase activity
GQR98_RS06345	COG2204	response regulator
GQR98_RS06385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GQR98_RS06395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQR98_RS06415	COG0330	HflC and HflK could
GQR98_RS06430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQR98_RS06440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GQR98_RS06445	COG0445	tRNA wobble uridine modification
GQR98_RS06460	COG0470	DNA polymerase III
GQR98_RS06465	COG0126	phosphoglycerate kinase activity
GQR98_RS06470	COG1388	LysM domain
GQR98_RS06470	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQR98_RS06480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQR98_RS06525	COG1086	Polysaccharide biosynthesis protein
GQR98_RS06530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQR98_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS06545	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GQR98_RS06550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQR98_RS06565	COG2089	acid synthase
GQR98_RS06595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR98_RS06605	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS06615	COG0151	Belongs to the GarS family
GQR98_RS06630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQR98_RS06690	COG0756	dUTP diphosphatase activity
GQR98_RS06700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQR98_RS06705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQR98_RS06710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQR98_RS06715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GQR98_RS06720	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQR98_RS06725	COG0356	it plays a direct role in the translocation of protons across the membrane
GQR98_RS06750	COG0720	synthase
GQR98_RS06775	COG1629	transport
GQR98_RS06775	COG4206	TonB-dependent receptor
GQR98_RS06815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQR98_RS06820	COG4206	TonB-dependent receptor
GQR98_RS06820	COG1629	transport
GQR98_RS06835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR98_RS06840	COG1554	hydrolase, family 65, central catalytic
GQR98_RS06845	COG1082	Xylose isomerase domain protein TIM barrel
GQR98_RS06850	COG0366	Alpha amylase catalytic
GQR98_RS06855	COG2819	hydrolase of the alpha beta superfamily
GQR98_RS06865	COG0366	Alpha amylase catalytic
GQR98_RS06895	COG4206	TonB-dependent receptor
GQR98_RS06895	COG1629	transport
GQR98_RS06915	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS06940	COG1074	ATP-dependent DNA helicase activity
GQR98_RS06960	COG0328	RNA-DNA hybrid ribonuclease activity
GQR98_RS06960	COG3341	Caulimovirus viroplasmin
GQR98_RS06970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQR98_RS06975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQR98_RS06980	COG0571	ribonuclease III activity
GQR98_RS06990	COG0469	pyruvate kinase activity
GQR98_RS07005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQR98_RS07045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQR98_RS07055	COG1381	Involved in DNA repair and RecF pathway recombination
GQR98_RS07085	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GQR98_RS07095	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GQR98_RS07100	COG1752	Esterase of the alpha-beta hydrolase superfamily
GQR98_RS07105	COG0322	excinuclease ABC activity
GQR98_RS07110	COG4067	protein conserved in archaea
GQR98_RS07110	COG0189	ligase activity
GQR98_RS07115	COG0189	ligase activity
GQR98_RS07125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQR98_RS07130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQR98_RS07140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQR98_RS07150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GQR98_RS07165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GQR98_RS07170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GQR98_RS07185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQR98_RS07190	COG1629	transport
GQR98_RS07190	COG4206	TonB-dependent receptor
GQR98_RS07205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQR98_RS07220	COG0587	DNA-directed DNA polymerase activity
GQR98_RS07225	COG2885	chlorophyll binding
GQR98_RS07235	COG1528	Iron-storage protein
GQR98_RS07240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR98_RS07240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR98_RS07245	COG1619	proteins homologs of microcin C7 resistance protein MccF
GQR98_RS07260	COG0484	heat shock protein binding
GQR98_RS07295	COG1418	mRNA catabolic process
GQR98_RS07330	COG1024	Enoyl-CoA hydratase
GQR98_RS07335	COG5000	phosphorelay sensor kinase activity
GQR98_RS07345	COG3483	tryptophan 2,3-dioxygenase activity
GQR98_RS07355	COG0166	Belongs to the GPI family
GQR98_RS07370	COG2356	endonuclease I
GQR98_RS07410	COG3279	Response regulator of the LytR AlgR family
GQR98_RS07415	COG2972	Histidine kinase
GQR98_RS07415	COG0745	RESPONSE REGULATOR receiver
GQR98_RS07420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQR98_RS07440	COG2151	metal-sulfur cluster biosynthetic enzyme
GQR98_RS07445	COG2166	iron-sulfur cluster assembly
GQR98_RS07455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQR98_RS07460	COG0719	Fe-S assembly protein
GQR98_RS07465	COG0396	ATPase activity
GQR98_RS07475	COG0719	Fe-S assembly protein
GQR98_RS07480	COG0316	Belongs to the HesB IscA family
GQR98_RS07490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQR98_RS07510	COG0527	aspartate kinase activity
GQR98_RS07535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQR98_RS07540	COG2239	Acts as a magnesium transporter
GQR98_RS07555	COG2205	protein histidine kinase activity
GQR98_RS07565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GQR98_RS07585	COG2363	Small membrane protein
GQR98_RS07590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GQR98_RS07605	COG2095	MarC family integral membrane protein
GQR98_RS07615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQR98_RS07615	COG1328	CTP reductase activity
GQR98_RS07620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQR98_RS07635	COG0708	Exodeoxyribonuclease III
GQR98_RS07640	COG1360	Flagellar Motor Protein
GQR98_RS07645	COG1522	sequence-specific DNA binding
GQR98_RS07655	COG0423	glycine-tRNA ligase activity
GQR98_RS07660	COG1040	competence protein
GQR98_RS07670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GQR98_RS07675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQR98_RS07685	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GQR98_RS07700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GQR98_RS07715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQR98_RS07730	COG3852	Histidine kinase
GQR98_RS07745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GQR98_RS07775	COG3279	Response regulator of the LytR AlgR family
GQR98_RS07780	COG0745	RESPONSE REGULATOR receiver
GQR98_RS07780	COG2972	Histidine kinase
GQR98_RS07790	COG0519	Catalyzes the synthesis of GMP from XMP
GQR98_RS07805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQR98_RS07810	COG1968	undecaprenyl-diphosphatase activity
GQR98_RS07825	COG2177	Part of the ABC transporter FtsEX involved in
GQR98_RS07855	COG0702	epimerase
GQR98_RS07870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQR98_RS07900	COG0745	RESPONSE REGULATOR receiver
GQR98_RS07905	COG5002	protein histidine kinase activity
GQR98_RS07910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQR98_RS07915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQR98_RS07930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQR98_RS07935	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GQR98_RS07955	COG0489	protein tyrosine kinase activity
GQR98_RS07965	COG0633	Ferredoxin
GQR98_RS07980	COG0437	4 iron, 4 sulfur cluster binding
GQR98_RS08005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQR98_RS08010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQR98_RS08015	COG2255	four-way junction helicase activity
GQR98_RS08020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQR98_RS08025	COG4251	negative regulation of phosphorylation
GQR98_RS08035	COG0281	malic enzyme
GQR98_RS08035	COG0280	phosphate acetyltransferase
GQR98_RS08040	COG0632	four-way junction helicase activity
GQR98_RS08050	COG0509	glycine decarboxylation via glycine cleavage system
GQR98_RS08085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GQR98_RS08095	COG4206	TonB-dependent receptor
GQR98_RS08095	COG1629	transport
GQR98_RS08110	COG1629	transport
GQR98_RS08110	COG4206	TonB-dependent receptor
GQR98_RS08120	COG3291	Pkd domain containing protein
GQR98_RS08120	COG4412	M6 family metalloprotease domain protein
GQR98_RS08135	COG2271	Major facilitator Superfamily
GQR98_RS08145	COG1609	Transcriptional regulator
GQR98_RS08160	COG0561	phosphatase activity
GQR98_RS08270	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQR98_RS08275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQR98_RS08295	COG2315	Protein conserved in bacteria
GQR98_RS08305	COG2824	Alkylphosphonate utilization operon protein PhnA
GQR98_RS08340	COG1774	PSP1 C-terminal conserved region
GQR98_RS08350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GQR98_RS08355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GQR98_RS08365	COG4172	Belongs to the ABC transporter superfamily
GQR98_RS08385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GQR98_RS08390	COG1253	flavin adenine dinucleotide binding
GQR98_RS08395	COG0113	porphobilinogen synthase activity
GQR98_RS08410	COG3012	SEC-C Motif Domain Protein
GQR98_RS08415	COG0408	coproporphyrinogen oxidase activity
GQR98_RS08430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQR98_RS08435	COG0569	domain protein
GQR98_RS08440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQR98_RS08450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GQR98_RS08465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQR98_RS08480	COG0589	response to stress
GQR98_RS08485	COG0779	Required for maturation of 30S ribosomal subunits
GQR98_RS08490	COG0195	Participates in both transcription termination and antitermination
GQR98_RS08495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQR98_RS08500	COG1794	racemase activity, acting on amino acids and derivatives
GQR98_RS08520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GQR98_RS08525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GQR98_RS08530	COG0228	four-way junction DNA binding
GQR98_RS08535	COG2706	6-phosphogluconolactonase activity
GQR98_RS08570	COG3118	belongs to the thioredoxin family
GQR98_RS08575	COG0740	serine-type endopeptidase activity
GQR98_RS08605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR98_RS08620	COG1519	Transferase
GQR98_RS08620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQR98_RS08630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQR98_RS08635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQR98_RS08640	COG0109	protoheme IX farnesyltransferase activity
GQR98_RS08645	COG1845	cytochrome c oxidase, subunit III
GQR98_RS08665	COG1999	signal sequence binding
GQR98_RS08670	COG2322	membrane
GQR98_RS08680	COG1136	(ABC) transporter
GQR98_RS08685	COG0577	efflux transmembrane transporter activity
GQR98_RS08685	COG1136	(ABC) transporter
GQR98_RS08690	COG1136	(ABC) transporter
GQR98_RS08690	COG0577	efflux transmembrane transporter activity
GQR98_RS08695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR98_RS08705	COG1214	PFAM Peptidase M22, glycoprotease
GQR98_RS08710	COG0668	transmembrane transport
GQR98_RS08715	COG1331	Highly conserved protein containing a thioredoxin domain
GQR98_RS08725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GQR98_RS08740	COG3275	phosphorelay sensor kinase activity
GQR98_RS08750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GQR98_RS08760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GQR98_RS08770	COG0772	Belongs to the SEDS family
GQR98_RS08775	COG0768	penicillin binding
GQR98_RS08790	COG1077	Cell shape determining protein MreB Mrl
GQR98_RS08795	COG0138	bifunctional purine biosynthesis protein purh
GQR98_RS08820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQR98_RS08825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GQR98_RS08830	COG0563	adenylate kinase activity
GQR98_RS08835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQR98_RS08885	COG1187	pseudouridine synthase activity
GQR98_RS08895	COG0010	Belongs to the arginase family
GQR98_RS08900	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GQR98_RS08905	COG3153	acetyltransferase
GQR98_RS08905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQR98_RS08940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GQR98_RS08945	COG0401	homolog of Blt101
GQR98_RS08955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQR98_RS08965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQR98_RS08975	COG1187	pseudouridine synthase activity
GQR98_RS08990	COG0321	lipoyl(octanoyl) transferase activity
GQR98_RS08995	COG0358	DNA primase activity
GQR98_RS09000	COG2197	response regulator
GQR98_RS09005	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GQR98_RS09020	COG0295	cytidine deaminase activity
GQR98_RS09025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQR98_RS09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR98_RS09055	COG2885	chlorophyll binding
GQR98_RS09055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQR98_RS09060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR98_RS09075	COG1506	peptidase
GQR98_RS09075	COG0823	Involved in the tonB-independent uptake of proteins
GQR98_RS09080	COG3104	oligopeptide transport
GQR98_RS09085	COG3104	oligopeptide transport
GQR98_RS09095	COG0658	competence protein
GQR98_RS09095	COG2333	competence protein COMEC
GQR98_RS09100	COG0791	NLP P60 protein
GQR98_RS09105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR98_RS09115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQR98_RS09125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQR98_RS09130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQR98_RS09140	COG2001	Belongs to the MraZ family
GQR98_RS09145	COG0275	rRNA processing
GQR98_RS09155	COG0768	penicillin binding
GQR98_RS09160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GQR98_RS09165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQR98_RS09170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQR98_RS09175	COG0772	Belongs to the SEDS family
GQR98_RS09180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GQR98_RS09185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQR98_RS09200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQR98_RS09205	COG1610	YqeY-like protein
GQR98_RS09215	COG3228	Belongs to the MtfA family
GQR98_RS09225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQR98_RS09235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQR98_RS09260	COG3275	phosphorelay sensor kinase activity
GQR98_RS09265	COG2885	chlorophyll binding
GQR98_RS09290	COG1185	polyribonucleotide nucleotidyltransferase activity
GQR98_RS09295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQR98_RS09320	COG5002	protein histidine kinase activity
GQR98_RS09320	COG3447	MASE1 domain protein
GQR98_RS09320	COG5001	Diguanylate cyclase
GQR98_RS09325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GQR98_RS09330	COG0191	fructose-bisphosphate aldolase activity
GQR98_RS09355	COG2226	methyltransferase
GQR98_RS09360	COG0569	domain protein
GQR98_RS09370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQR98_RS09380	COG2205	protein histidine kinase activity
GQR98_RS09380	COG0784	Response regulator, receiver
GQR98_RS09385	COG2003	Belongs to the UPF0758 family
GQR98_RS09415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQR98_RS09425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQR98_RS09470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQR98_RS09480	COG2264	protein methyltransferase activity
GQR98_RS09485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQR98_RS09495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GQR98_RS09500	COG0596	Alpha beta hydrolase
GQR98_RS09505	COG1950	PFAM Membrane protein of
GQR98_RS09510	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQR98_RS09520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQR98_RS09525	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GQR98_RS09545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GQR98_RS09550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQR98_RS09560	COG4206	TonB-dependent receptor
GQR98_RS09560	COG1629	transport
GQR98_RS09575	COG1629	transport
GQR98_RS09575	COG4206	TonB-dependent receptor
GQR98_RS09585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQR98_RS09590	COG0049	tRNA binding
GQR98_RS09595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQR98_RS09600	COG0051	transcription antitermination factor activity, RNA binding
GQR98_RS09605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQR98_RS09610	COG0088	Forms part of the polypeptide exit tunnel
GQR98_RS09615	COG0089	rRNA binding
GQR98_RS09620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQR98_RS09625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQR98_RS09630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GQR98_RS09635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQR98_RS09640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GQR98_RS09645	COG0255	Belongs to the universal ribosomal protein uL29 family
GQR98_RS09650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQR98_RS09655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQR98_RS09660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQR98_RS09665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQR98_RS09670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQR98_RS09675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQR98_RS09680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQR98_RS09685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQR98_RS09690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQR98_RS09695	COG1841	ribosomal large subunit assembly
GQR98_RS09700	COG0200	Binds to the 23S rRNA
GQR98_RS09710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GQR98_RS09715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQR98_RS09720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQR98_RS09725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQR98_RS09730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQR98_RS09735	COG0202	RNA polymerase activity
GQR98_RS09740	COG0203	ribosomal protein L17
GQR98_RS09745	COG0505	Belongs to the CarA family
GQR98_RS09750	COG0148	phosphopyruvate hydratase activity
GQR98_RS09770	COG2205	protein histidine kinase activity
GQR98_RS09775	COG0018	arginyl-trna synthetase
GQR98_RS09790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQR98_RS09795	COG1629	transport
GQR98_RS09795	COG4206	TonB-dependent receptor
GQR98_RS09820	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS09825	COG0463	Glycosyl transferase, family 2
GQR98_RS09840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR98_RS09900	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GQR98_RS09915	COG0463	Glycosyl transferase, family 2
GQR98_RS09985	COG1960	acyl-CoA dehydrogenase activity
GQR98_RS10000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GQR98_RS10010	COG0848	biopolymer transport protein
GQR98_RS10020	COG0285	dihydrofolate synthase activity
GQR98_RS10040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQR98_RS10045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GQR98_RS10060	COG0501	Belongs to the peptidase M48B family
GQR98_RS10105	COG0592	DNA-directed DNA polymerase activity
GQR98_RS10125	COG1702	phosphate starvation-inducible protein PhoH
GQR98_RS10135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQR98_RS10140	COG0546	phosphoglycolate phosphatase activity
GQR98_RS10160	COG1115	amino acid carrier protein
GQR98_RS10170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS10175	COG2032	superoxide dismutase activity
GQR98_RS10180	COG2207	Transcriptional regulator
GQR98_RS10185	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS10195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GQR98_RS10245	COG1132	(ABC) transporter
GQR98_RS10255	COG0187	DNA topoisomerase II activity
GQR98_RS10285	COG3712	iron ion homeostasis
GQR98_RS10305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQR98_RS10310	COG0038	chloride channel
GQR98_RS10350	COG1309	transcriptional regulator
GQR98_RS10360	COG0659	secondary active sulfate transmembrane transporter activity
GQR98_RS10365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQR98_RS10370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQR98_RS10375	COG1181	Belongs to the D-alanine--D-alanine ligase family
GQR98_RS10385	COG0564	pseudouridine synthase activity
GQR98_RS10400	COG0300	oxidoreductase activity
GQR98_RS10405	COG0798	PFAM Bile acid sodium symporter
GQR98_RS10420	COG0640	Transcriptional regulator
GQR98_RS10430	COG0076	glutamate decarboxylase activity
GQR98_RS10445	COG3022	response to hydroperoxide
GQR98_RS10465	COG1187	pseudouridine synthase activity
GQR98_RS10480	COG0545	Peptidyl-prolyl cis-trans isomerase
GQR98_RS10490	COG0326	Molecular chaperone. Has ATPase activity
GQR98_RS10495	COG1506	peptidase
GQR98_RS10500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQR98_RS10520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS10525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQR98_RS10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQR98_RS10545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQR98_RS10550	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQR98_RS10560	COG1058	Belongs to the CinA family
GQR98_RS10560	COG1546	Belongs to the CinA family
GQR98_RS10565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQR98_RS10570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQR98_RS10580	COG0552	protein localization to endoplasmic reticulum
GQR98_RS10595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQR98_RS10610	COG0653	protein targeting
GQR98_RS10625	COG2885	chlorophyll binding
GQR98_RS10625	COG3047	cAMP biosynthetic process
GQR98_RS10670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQR98_RS10680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQR98_RS10680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GQR98_RS10685	COG1090	epimerase
GQR98_RS10700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQR98_RS10705	COG0484	heat shock protein binding
GQR98_RS10710	COG4152	abc transporter atp-binding protein
GQR98_RS10715	COG1668	transmembrane transport
GQR98_RS10720	COG3264	Mechanosensitive ion channel
GQR98_RS10720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GQR98_RS10740	COG0513	Belongs to the DEAD box helicase family
GQR98_RS10745	COG2258	MOSC domain
GQR98_RS10760	COG3275	phosphorelay sensor kinase activity
GQR98_RS10770	COG3279	Response regulator of the LytR AlgR family
GQR98_RS10795	COG1289	transmembrane transporter activity
GQR98_RS10800	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS10805	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS10840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQR98_RS10845	COG0129	dihydroxy-acid dehydratase activity
GQR98_RS10850	COG0028	Belongs to the TPP enzyme family
GQR98_RS10860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GQR98_RS10865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQR98_RS10870	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS10875	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GQR98_RS10910	COG0673	inositol 2-dehydrogenase activity
GQR98_RS10935	COG0137	argininosuccinate synthase activity
GQR98_RS10940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GQR98_RS10945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQR98_RS10950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQR98_RS10960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GQR98_RS10970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQR98_RS10980	COG0165	Argininosuccinate lyase
GQR98_RS10990	COG0473	3-isopropylmalate dehydrogenase activity
GQR98_RS10995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQR98_RS11030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GQR98_RS11045	COG1247	-acetyltransferase
GQR98_RS11055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQR98_RS11075	COG1132	(ABC) transporter
GQR98_RS11080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQR98_RS11090	COG1862	Preprotein translocase
GQR98_RS11105	COG0484	heat shock protein binding
GQR98_RS11110	COG1960	acyl-CoA dehydrogenase activity
GQR98_RS11115	COG0183	Belongs to the thiolase family
GQR98_RS11120	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQR98_RS11120	COG1024	Enoyl-CoA hydratase
GQR98_RS11125	COG1846	Transcriptional regulator
GQR98_RS11130	COG1022	Amp-dependent synthetase and ligase
GQR98_RS11150	COG2356	endonuclease I
GQR98_RS11155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQR98_RS11155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQR98_RS11160	COG1595	DNA-templated transcription, initiation
GQR98_RS11225	COG1879	ABC-type sugar transport system periplasmic component
GQR98_RS11235	COG1172	Belongs to the binding-protein-dependent transport system permease family
GQR98_RS11240	COG0246	Mannitol dehydrogenase
GQR98_RS11250	COG0246	Mannitol dehydrogenase
GQR98_RS11275	COG1132	(ABC) transporter
GQR98_RS11280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQR98_RS11285	COG0463	Glycosyl transferase, family 2
GQR98_RS11295	COG0254	rRNA binding
GQR98_RS11315	COG4166	transmembrane transport
GQR98_RS11320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQR98_RS11350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GQR98_RS11355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQR98_RS11375	COG1322	Protein conserved in bacteria
GQR98_RS11380	COG1120	ATPase activity
GQR98_RS11385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQR98_RS11460	COG0484	heat shock protein binding
GQR98_RS11465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQR98_RS11485	COG3291	Pkd domain containing protein
GQR98_RS11505	COG0501	Belongs to the peptidase M48B family
GQR98_RS11510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQR98_RS11525	COG0402	S-adenosylhomocysteine deaminase activity
GQR98_RS11535	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQR98_RS11540	COG0357	Ribosomal RNA small subunit methyltransferase G
GQR98_RS11545	COG3239	Fatty acid desaturase
GQR98_RS11560	COG2967	ApaG domain
GQR98_RS11575	COG1805	sodium ion transport
GQR98_RS11580	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR98_RS11585	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR98_RS11590	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GQR98_RS11600	COG2201	protein-glutamate methylesterase activity
GQR98_RS11605	COG4251	negative regulation of phosphorylation
GQR98_RS11615	COG1477	protein flavinylation
GQR98_RS11645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQR98_RS11660	COG4206	TonB-dependent receptor
GQR98_RS11660	COG1629	transport
GQR98_RS11665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GQR98_RS11690	COG2814	Major facilitator Superfamily
GQR98_RS11700	COG3119	arylsulfatase activity
GQR98_RS11710	COG1082	Xylose isomerase domain protein TIM barrel
GQR98_RS11715	COG3119	arylsulfatase activity
GQR98_RS11735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQR98_RS11740	COG3119	arylsulfatase activity
GQR98_RS11755	COG4206	TonB-dependent receptor
GQR98_RS11755	COG1629	transport
GQR98_RS11760	COG0561	phosphatase activity
GQR98_RS11810	COG2885	chlorophyll binding
GQR98_RS11810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQR98_RS11815	COG0788	formyltetrahydrofolate deformylase activity
GQR98_RS11820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQR98_RS11820	COG1703	isobutyryl-CoA mutase activity
GQR98_RS11820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQR98_RS11835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GQR98_RS11840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GQR98_RS11865	COG0556	nucleotide-excision repair
GQR98_RS11935	COG1858	cytochrome C peroxidase
GQR98_RS11950	COG0783	Belongs to the Dps family
GQR98_RS11965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GQR98_RS11970	COG1301	dicarboxylic acid transport
GQR98_RS11980	COG3738	Protein conserved in bacteria
GQR98_RS11985	COG2897	thiosulfate sulfurtransferase activity
GQR98_RS12000	COG3420	alginic acid biosynthetic process
GQR98_RS12005	COG2860	membrane
GQR98_RS12035	COG0714	Associated with various cellular activities
GQR98_RS12045	COG2195	Cleaves the N-terminal amino acid of tripeptides
GQR98_RS12050	COG0167	dihydroorotate dehydrogenase activity
GQR98_RS12090	COG0517	IMP dehydrogenase activity
GQR98_RS12090	COG0516	GMP reductase activity
GQR98_RS12105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQR98_RS12125	COG3263	regulation of cellular component size
GQR98_RS12140	COG1612	heme a metabolic process
GQR98_RS12145	COG0617	tRNA 3'-terminal CCA addition
GQR98_RS12150	COG0009	L-threonylcarbamoyladenylate synthase
GQR98_RS12165	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS12170	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS12175	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS12180	COG2171	N-acyltransferase activity
GQR98_RS12190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQR98_RS12195	COG0242	peptide deformylase activity
GQR98_RS12220	COG0343	queuine tRNA-ribosyltransferase activity
GQR98_RS12235	COG0825	malonyl-CoA metabolic process
GQR98_RS12240	COG0305	Participates in initiation and elongation during chromosome replication
GQR98_RS12255	COG0432	Pfam Uncharacterised protein family UPF0047
GQR98_RS12270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQR98_RS12275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQR98_RS12280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQR98_RS12285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQR98_RS12350	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GQR98_RS12365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQR98_RS12375	COG3011	Protein conserved in bacteria
GQR98_RS12385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQR98_RS12390	COG2022	thiamine diphosphate biosynthetic process
GQR98_RS12395	COG0352	thiamine-phosphate diphosphorylase activity
GQR98_RS12400	COG0352	thiamine-phosphate diphosphorylase activity
GQR98_RS12400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GQR98_RS12400	COG0351	phosphomethylpyrimidine kinase
GQR98_RS12410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GQR98_RS12420	COG1193	negative regulation of DNA recombination
GQR98_RS12465	COG0300	oxidoreductase activity
GQR98_RS12475	COG0488	(ABC) transporter
GQR98_RS12515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR98_RS12525	COG2076	Multidrug Resistance protein
GQR98_RS12565	COG1611	Belongs to the LOG family
GQR98_RS12570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQR98_RS12605	COG0405	Gamma-glutamyltransferase
GQR98_RS12630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQR98_RS12640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQR98_RS12660	COG0450	alkyl hydroperoxide reductase
GQR98_RS12670	COG1393	Belongs to the ArsC family
GQR98_RS12685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQR98_RS12690	COG1770	oligopeptidase
GQR98_RS12700	COG0156	8-amino-7-oxononanoate synthase activity
GQR98_RS12735	COG0420	3'-5' exonuclease activity
GQR98_RS12740	COG0419	ATPase involved in DNA repair
GQR98_RS12755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQR98_RS12765	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GQR98_RS12775	COG2226	methyltransferase
GQR98_RS12780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQR98_RS12780	COG0116	Belongs to the methyltransferase superfamily
GQR98_RS12795	COG1169	isochorismate synthase
GQR98_RS12800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GQR98_RS12810	COG2996	Protein conserved in bacteria
GQR98_RS12820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GQR98_RS12865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GQR98_RS12875	COG0556	nucleotide-excision repair
GQR98_RS12925	COG3177	Filamentation induced by cAMP protein fic
GQR98_RS12975	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GQR98_RS13010	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GQR98_RS13020	COG3119	arylsulfatase activity
GQR98_RS13070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GQR98_RS13075	COG4206	TonB-dependent receptor
GQR98_RS13075	COG1629	transport
GQR98_RS13085	COG3537	Alpha-1,2-mannosidase
GQR98_RS13090	COG3119	arylsulfatase activity
GQR98_RS13095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQR98_RS13105	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS13110	COG3119	arylsulfatase activity
GQR98_RS13120	COG3119	arylsulfatase activity
GQR98_RS13130	COG3119	arylsulfatase activity
GQR98_RS13145	COG3119	arylsulfatase activity
GQR98_RS13165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQR98_RS13170	COG1446	asparaginase
GQR98_RS13175	COG3537	Alpha-1,2-mannosidase
GQR98_RS13190	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GQR98_RS13200	COG3537	Alpha-1,2-mannosidase
GQR98_RS13205	COG3275	phosphorelay sensor kinase activity
GQR98_RS13210	COG3279	Response regulator of the LytR AlgR family
GQR98_RS13215	COG0363	glucosamine-6-phosphate deaminase activity
GQR98_RS13220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQR98_RS13225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQR98_RS13230	COG4206	TonB-dependent receptor
GQR98_RS13230	COG1629	transport
GQR98_RS13240	COG4206	TonB-dependent receptor
GQR98_RS13240	COG1629	transport
GQR98_RS13260	COG1794	racemase activity, acting on amino acids and derivatives
GQR98_RS13265	COG3119	arylsulfatase activity
GQR98_RS13315	COG2201	protein-glutamate methylesterase activity
GQR98_RS13320	COG5002	protein histidine kinase activity
GQR98_RS13335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQR98_RS13405	COG2972	Histidine kinase
GQR98_RS13405	COG0745	RESPONSE REGULATOR receiver
GQR98_RS13410	COG3279	Response regulator of the LytR AlgR family
GQR98_RS13420	COG0069	glutamate synthase activity
GQR98_RS13440	COG0009	L-threonylcarbamoyladenylate synthase
GQR98_RS13465	COG2801	Transposase and inactivated derivatives
GQR98_RS13525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GQR98_RS13545	COG1575	Belongs to the MenA family. Type 1 subfamily
GQR98_RS13550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQR98_RS13555	COG4948	Mandelate Racemase Muconate Lactonizing
GQR98_RS13560	COG1266	CAAX protease self-immunity
GQR98_RS13570	COG0616	signal peptide processing
GQR98_RS13585	COG1629	transport
GQR98_RS13585	COG4206	TonB-dependent receptor
GQR98_RS13590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQR98_RS13605	COG1846	Transcriptional regulator
GQR98_RS13610	COG1741	Belongs to the pirin family
GQR98_RS13615	COG2814	Major facilitator Superfamily
GQR98_RS13625	COG0488	(ABC) transporter
GQR98_RS13660	COG0494	nUDIX hydrolase
GQR98_RS13695	COG1047	Peptidyl-prolyl cis-trans
GQR98_RS13700	COG4251	negative regulation of phosphorylation
GQR98_RS13730	COG0302	gtp cyclohydrolase
GQR98_RS13740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQR98_RS13755	COG1760	l-serine dehydratase
GQR98_RS13760	COG0443	Heat shock 70 kDa protein
GQR98_RS13770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQR98_RS13775	COG2070	2-Nitropropane dioxygenase
GQR98_RS13780	COG0667	Aldo Keto reductase
GQR98_RS13785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GQR98_RS13790	COG1595	DNA-templated transcription, initiation
GQR98_RS13820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQR98_RS13825	COG0668	transmembrane transport
GQR98_RS13830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQR98_RS13865	COG1104	cysteine desulfurase activity
GQR98_RS13900	COG1418	mRNA catabolic process
GQR98_RS13910	COG4974	Belongs to the 'phage' integrase family
GQR98_RS13920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GQR98_RS13930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQR98_RS13935	COG1252	NADH dehydrogenase
GQR98_RS13945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQR98_RS13960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GQR98_RS13975	COG0542	response to heat
GQR98_RS13990	COG0791	NLP P60 protein
GQR98_RS13995	COG0183	Belongs to the thiolase family
GQR98_RS14030	COG3852	Histidine kinase
GQR98_RS14040	COG2205	protein histidine kinase activity
GQR98_RS14040	COG0784	Response regulator, receiver
GQR98_RS14090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQR98_RS14105	COG0235	Class ii aldolase
GQR98_RS14110	COG4977	sequence-specific DNA binding
GQR98_RS14115	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS14120	COG0738	Major facilitator superfamily
GQR98_RS14130	COG1304	FMN binding
GQR98_RS14160	COG0513	Belongs to the DEAD box helicase family
GQR98_RS14175	COG0037	tRNA processing
GQR98_RS14180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GQR98_RS14205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GQR98_RS14210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQR98_RS14220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQR98_RS14250	COG2223	nitrite transmembrane transporter activity
GQR98_RS14255	COG0243	molybdopterin cofactor binding
GQR98_RS14265	COG0784	Response regulator, receiver
GQR98_RS14275	COG4251	negative regulation of phosphorylation
GQR98_RS14285	COG4251	negative regulation of phosphorylation
GQR98_RS14295	COG3279	Response regulator of the LytR AlgR family
GQR98_RS14305	COG2340	Cysteine-rich secretory protein family
GQR98_RS14345	COG0745	RESPONSE REGULATOR receiver
GQR98_RS14350	COG0745	RESPONSE REGULATOR receiver
GQR98_RS14360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQR98_RS14365	COG0315	cyclic pyranopterin monophosphate synthase activity
GQR98_RS14365	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQR98_RS14375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQR98_RS14385	COG0746	molybdenum cofactor guanylyltransferase activity
GQR98_RS14400	COG0303	'Molybdopterin
GQR98_RS14405	COG3005	denitrification pathway
GQR98_RS14410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GQR98_RS14415	COG1333	cytochrome c biogenesis protein
GQR98_RS14415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQR98_RS14425	COG1116	anion transmembrane transporter activity
GQR98_RS14425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQR98_RS14430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GQR98_RS14435	COG1116	anion transmembrane transporter activity
GQR98_RS14440	COG1116	anion transmembrane transporter activity
GQR98_RS14450	COG4206	TonB-dependent receptor
GQR98_RS14450	COG1629	transport
GQR98_RS14485	COG0606	chelatase, subunit chli
GQR98_RS14490	COG3781	membrane
GQR98_RS14500	COG0300	oxidoreductase activity
GQR98_RS14545	COG1970	mechanosensitive ion channel activity
GQR98_RS14550	COG1609	Transcriptional regulator
GQR98_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS14560	COG1312	Catalyzes the dehydration of D-mannonate
GQR98_RS14565	COG1904	glucuronate isomerase
GQR98_RS14570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GQR98_RS14585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQR98_RS14595	COG1629	transport
GQR98_RS14595	COG4206	TonB-dependent receptor
GQR98_RS14610	COG0628	permease
GQR98_RS14635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQR98_RS14645	COG0205	6-phosphofructokinase activity
GQR98_RS14660	COG1119	ATPase activity
GQR98_RS14670	COG2308	Evidence 4 Homologs of previously reported genes of
GQR98_RS14670	COG2307	Protein conserved in bacteria
GQR98_RS14685	COG3437	response regulator, receiver
GQR98_RS14685	COG3850	Histidine kinase
GQR98_RS14685	COG2205	protein histidine kinase activity
GQR98_RS14685	COG4999	Histidine kinase
GQR98_RS14690	COG0251	oxidation-reduction process
GQR98_RS14700	COG0860	N-Acetylmuramoyl-L-alanine amidase
GQR98_RS14710	COG0247	lactate metabolic process
GQR98_RS14710	COG2181	nitrate reductase activity
GQR98_RS14720	COG2181	nitrate reductase activity
GQR98_RS14720	COG0247	lactate metabolic process
GQR98_RS14735	COG3830	Belongs to the UPF0237 family
GQR98_RS14735	COG0560	Phosphoserine phosphatase
GQR98_RS14750	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS14755	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS14765	COG1858	cytochrome C peroxidase
GQR98_RS14775	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GQR98_RS14780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQR98_RS14780	COG0519	Catalyzes the synthesis of GMP from XMP
GQR98_RS14795	COG3530	Putative quorum-sensing-regulated virulence factor
GQR98_RS14800	COG0277	FAD linked oxidase domain protein
GQR98_RS14800	COG0247	lactate metabolic process
GQR98_RS14805	COG0504	CTP synthase activity
GQR98_RS14810	COG0706	membrane insertase activity
GQR98_RS14845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQR98_RS14850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GQR98_RS14860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQR98_RS14880	COG4206	TonB-dependent receptor
GQR98_RS14880	COG1629	transport
GQR98_RS14885	COG0012	GTP binding
GQR98_RS14915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQR98_RS14920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQR98_RS14930	COG2176	DNA-directed DNA polymerase activity
GQR98_RS14940	COG1250	3-hydroxyacyl-CoA dehydrogenase
GQR98_RS14945	COG0673	inositol 2-dehydrogenase activity
GQR98_RS14950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQR98_RS14980	COG4585	Histidine kinase
GQR98_RS14985	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS14990	COG0564	pseudouridine synthase activity
GQR98_RS14995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GQR98_RS15000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQR98_RS15005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQR98_RS15015	COG1234	tRNA 3'-trailer cleavage
GQR98_RS15040	COG1522	sequence-specific DNA binding
GQR98_RS15045	COG1696	Membrane protein involved in D-alanine export
GQR98_RS15075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQR98_RS15080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQR98_RS15110	COG1216	Glycosyl transferase, family 2
GQR98_RS15110	COG1442	glycosyl transferase family 8
GQR98_RS15125	COG0438	transferase activity, transferring glycosyl groups
GQR98_RS15150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQR98_RS15155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GQR98_RS15160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQR98_RS15165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQR98_RS15185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GQR98_RS15200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GQR98_RS15210	COG0686	Belongs to the AlaDH PNT family
GQR98_RS15225	COG2204	response regulator
GQR98_RS15230	COG1078	dGTPase activity
GQR98_RS15240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GQR98_RS15240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQR98_RS15245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GQR98_RS15250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQR98_RS15260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GQR98_RS15265	COG0612	Peptidase, M16
GQR98_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS15290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GQR98_RS15295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQR98_RS15300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQR98_RS15315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GQR98_RS15320	COG0107	imidazoleglycerol-phosphate synthase activity
GQR98_RS15325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GQR98_RS15325	COG0140	phosphoribosyl-ATP diphosphatase activity
GQR98_RS15335	COG0783	Belongs to the Dps family
GQR98_RS15365	COG1607	acyl-coa hydrolase
GQR98_RS15370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GQR98_RS15375	COG0066	3-isopropylmalate dehydratase activity
GQR98_RS15380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GQR98_RS15385	COG0473	3-isopropylmalate dehydrogenase activity
GQR98_RS15420	COG0668	transmembrane transport
GQR98_RS15425	COG2814	Major facilitator Superfamily
GQR98_RS15435	COG0784	Response regulator, receiver
GQR98_RS15435	COG5002	protein histidine kinase activity
GQR98_RS15470	COG0415	Belongs to the DNA photolyase family
GQR98_RS15475	COG1231	oxidoreductase activity
GQR98_RS15495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQR98_RS15515	COG4181	ATPase activity
GQR98_RS15570	COG1136	(ABC) transporter
GQR98_RS15575	COG0523	cobalamin synthesis protein
GQR98_RS15580	COG0523	cobalamin synthesis protein
GQR98_RS15585	COG0521	Mo-molybdopterin cofactor biosynthetic process
GQR98_RS15595	COG0302	gtp cyclohydrolase
GQR98_RS15620	COG0556	nucleotide-excision repair
GQR98_RS15630	COG3279	Response regulator of the LytR AlgR family
GQR98_RS15635	COG3275	phosphorelay sensor kinase activity
GQR98_RS15685	COG0028	Belongs to the TPP enzyme family
GQR98_RS15695	COG4251	negative regulation of phosphorylation
GQR98_RS15710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GQR98_RS15735	COG0590	tRNA wobble adenosine to inosine editing
GQR98_RS15740	COG1278	Cold shock
GQR98_RS15785	COG1132	(ABC) transporter
GQR98_RS15820	COG3279	Response regulator of the LytR AlgR family
GQR98_RS15840	COG3275	phosphorelay sensor kinase activity
GQR98_RS15850	COG1136	(ABC) transporter
GQR98_RS15850	COG0577	efflux transmembrane transporter activity
GQR98_RS15855	COG1136	(ABC) transporter
GQR98_RS15860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQR98_RS15870	COG1271	oxidase subunit
GQR98_RS15875	COG1294	oxidase, subunit
GQR98_RS15895	COG1309	transcriptional regulator
GQR98_RS15910	COG2130	NADP-dependent
GQR98_RS15915	COG1979	alcohol dehydrogenase
GQR98_RS15925	COG2205	protein histidine kinase activity
GQR98_RS15950	COG0513	Belongs to the DEAD box helicase family
GQR98_RS15960	COG1064	alcohol dehydrogenase
GQR98_RS15965	COG1764	response to oxidative stress
GQR98_RS15970	COG1902	pentaerythritol trinitrate reductase activity
GQR98_RS15990	COG2249	NAD(P)H dehydrogenase (quinone) activity
GQR98_RS15995	COG2095	MarC family integral membrane protein
GQR98_RS16000	COG0778	Nitroreductase
GQR98_RS16010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GQR98_RS16025	COG3256	nitric oxide reductase
GQR98_RS16065	COG1278	Cold shock
GQR98_RS16080	COG0667	Aldo Keto reductase
GQR98_RS16105	COG0022	dehydrogenase e1 component
GQR98_RS16125	COG0813	purine-nucleoside phosphorylase activity
GQR98_RS16135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQR98_RS16140	COG0460	homoserine dehydrogenase
GQR98_RS16140	COG0527	aspartate kinase activity
GQR98_RS16145	COG0083	homoserine kinase activity
GQR98_RS16150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQR98_RS16155	COG5002	protein histidine kinase activity
GQR98_RS16155	COG0784	Response regulator, receiver
GQR98_RS16160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQR98_RS16165	COG2066	Belongs to the glutaminase family
GQR98_RS16175	COG2154	pterin-4-alpha-carbinolamine dehydratase
GQR98_RS16180	COG0217	transcriptional regulatory protein
GQR98_RS16200	COG1454	alcohol dehydrogenase
GQR98_RS16215	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GQR98_RS16250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQR98_RS16275	COG0071	Belongs to the small heat shock protein (HSP20) family
GQR98_RS16305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GQR98_RS16375	COG1595	DNA-templated transcription, initiation
GQR98_RS16385	COG1703	isobutyryl-CoA mutase activity
GQR98_RS16390	COG0671	phosphoesterase, PA-phosphatase related
GQR98_RS16400	COG0534	Mate efflux family protein
GQR98_RS16415	COG0482	sulfurtransferase activity
GQR98_RS16430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GQR98_RS16455	COG0450	alkyl hydroperoxide reductase
GQR98_RS16475	COG2814	Major facilitator Superfamily
GQR98_RS16480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQR98_RS16505	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GQR98_RS16535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GQR98_RS16540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GQR98_RS16550	COG1674	ftsk spoiiie
GQR98_RS16565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQR98_RS16565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GQR98_RS16570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GQR98_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS16595	COG2186	Transcriptional regulator
GQR98_RS16605	COG4206	TonB-dependent receptor
GQR98_RS16605	COG1629	transport
GQR98_RS16615	COG1914	H( )-stimulated, divalent metal cation uptake system
GQR98_RS16620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GQR98_RS16635	COG0738	Major facilitator superfamily
GQR98_RS16660	COG0445	tRNA wobble uridine modification
GQR98_RS16665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQR98_RS16685	COG5002	protein histidine kinase activity
GQR98_RS16730	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS16735	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS16780	COG2197	response regulator
GQR98_RS16785	COG4251	negative regulation of phosphorylation
GQR98_RS16790	COG0861	Integral membrane protein TerC family
GQR98_RS16875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQR98_RS16890	COG3119	arylsulfatase activity
GQR98_RS16895	COG3250	beta-galactosidase activity
GQR98_RS16900	COG3250	beta-galactosidase activity
GQR98_RS16910	COG3119	arylsulfatase activity
GQR98_RS16940	COG0415	Belongs to the DNA photolyase family
GQR98_RS16955	COG3046	protein related to deoxyribodipyrimidine photolyase
GQR98_RS16975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQR98_RS17000	COG4191	Histidine kinase
GQR98_RS17005	COG0542	response to heat
GQR98_RS17010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQR98_RS17015	COG1984	allophanate hydrolase subunit 2
GQR98_RS17020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GQR98_RS17025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GQR98_RS17040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQR98_RS17065	COG0514	ATP-dependent DNA helicase (RecQ)
GQR98_RS17070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQR98_RS17075	COG0776	regulation of translation
GQR98_RS17080	COG1678	Uncharacterized ACR, COG1678
GQR98_RS17085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQR98_RS17120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQR98_RS17130	COG2201	protein-glutamate methylesterase activity
GQR98_RS17135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQR98_RS17215	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GQR98_RS17245	COG0629	single-stranded DNA binding
GQR98_RS17255	COG1629	transport
GQR98_RS17255	COG4206	TonB-dependent receptor
GQR98_RS17285	COG2160	L-arabinose isomerase activity
GQR98_RS17315	COG4206	TonB-dependent receptor
GQR98_RS17315	COG1629	transport
GQR98_RS17335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQR98_RS17340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GQR98_RS17360	COG3119	arylsulfatase activity
GQR98_RS17365	COG3119	arylsulfatase activity
GQR98_RS17375	COG1629	transport
GQR98_RS17375	COG4206	TonB-dependent receptor
GQR98_RS17390	COG3119	arylsulfatase activity
GQR98_RS17400	COG3119	arylsulfatase activity
GQR98_RS17435	COG3119	arylsulfatase activity
GQR98_RS17445	COG3119	arylsulfatase activity
GQR98_RS17450	COG3507	Belongs to the glycosyl hydrolase 43 family
GQR98_RS17460	COG3119	arylsulfatase activity
GQR98_RS17495	COG3119	arylsulfatase activity
GQR98_RS17540	COG3119	arylsulfatase activity
GQR98_RS17540	COG3119	arylsulfatase activity
GQR98_RS17545	COG3119	arylsulfatase activity
GQR98_RS17580	COG3119	arylsulfatase activity
GQR98_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS17600	COG3347	Dehydrogenase
GQR98_RS17605	COG4952	isomerase
GQR98_RS17625	COG1012	belongs to the aldehyde dehydrogenase family
GQR98_RS17655	COG3254	rhamnose metabolic process
GQR98_RS17680	COG3119	arylsulfatase activity
GQR98_RS17705	COG3119	arylsulfatase activity
GQR98_RS17725	COG4206	TonB-dependent receptor
GQR98_RS17725	COG1629	transport
GQR98_RS17740	COG3693	PFAM glycoside hydrolase, family 10
GQR98_RS17745	COG3693	PFAM glycoside hydrolase, family 10
GQR98_RS17815	COG3119	arylsulfatase activity
GQR98_RS17845	COG3119	arylsulfatase activity
GQR98_RS17950	COG4206	TonB-dependent receptor
GQR98_RS17950	COG1629	transport
GQR98_RS17980	COG3119	arylsulfatase activity
GQR98_RS17985	COG3119	arylsulfatase activity
GQR98_RS18025	COG3119	arylsulfatase activity
GQR98_RS18035	COG3119	arylsulfatase activity
GQR98_RS18115	COG0612	Peptidase, M16
GQR98_RS18160	COG3209	COG3209 Rhs family protein
GQR98_RS18170	COG3209	COG3209 Rhs family protein
GQR98_RS18215	COG0791	NLP P60 protein
GQR98_RS18260	COG0542	response to heat
GQR98_RS18320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GQR98_RS18355	COG4206	TonB-dependent receptor
GQR98_RS18355	COG1629	transport
GQR98_RS18365	COG0363	glucosamine-6-phosphate deaminase activity
GQR98_RS18385	COG1609	Transcriptional regulator
GQR98_RS18425	COG2211	Major facilitator Superfamily
GQR98_RS18475	COG4206	TonB-dependent receptor
GQR98_RS18475	COG1629	transport
GQR98_RS18480	COG1472	Belongs to the glycosyl hydrolase 3 family
GQR98_RS18485	COG4191	Histidine kinase
GQR98_RS18485	COG0745	RESPONSE REGULATOR receiver
GQR98_RS18485	COG2205	protein histidine kinase activity
GQR98_RS18495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GQR98_RS18500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQR98_RS18510	COG4948	Mandelate Racemase Muconate Lactonizing
GQR98_RS18545	COG3507	Belongs to the glycosyl hydrolase 43 family
GQR98_RS18555	COG4585	Histidine kinase
GQR98_RS18585	COG3118	belongs to the thioredoxin family
GQR98_RS18595	COG1335	isochorismatase
GQR98_RS18600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GQR98_RS18610	COG3119	arylsulfatase activity
GQR98_RS18625	COG1333	cytochrome c biogenesis protein
GQR98_RS18625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQR98_RS18650	COG0424	maF-like protein
GQR98_RS18660	COG0598	Magnesium transport protein CorA
GQR98_RS18675	COG0673	inositol 2-dehydrogenase activity
GQR98_RS18705	COG3347	Dehydrogenase
GQR98_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
GQR98_RS18710	COG4952	isomerase
GQR98_RS18715	COG1070	Carbohydrate kinase
GQR98_RS18735	COG2340	Cysteine-rich secretory protein family
GQR98_RS18740	COG0259	pyridoxamine-phosphate oxidase activity
GQR98_RS18750	COG1234	tRNA 3'-trailer cleavage
GQR98_RS18765	COG0540	Belongs to the ATCase OTCase family
GQR98_RS18770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GQR98_RS18805	COG1215	transferase activity, transferring glycosyl groups
GQR98_RS18815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQR98_RS18855	COG0463	Glycosyl transferase, family 2
GQR98_RS18855	COG1216	Glycosyl transferase, family 2
GQR98_RS18860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQR98_RS18865	COG0497	DNA recombination
GQR98_RS18890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQR98_RS18905	COG0737	Belongs to the 5'-nucleotidase family
GQR98_RS18920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQR98_RS18925	COG2890	protein-(glutamine-N5) methyltransferase activity
GQR98_RS18930	COG0456	acetyltransferase
GQR98_RS18940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQR98_RS18940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQR98_RS18950	COG1739	Uncharacterized protein family UPF0029
GQR98_RS18955	COG0824	Thioesterase