locus-tag	class	description
ALPR1_RS00015	COG0657	acetylesterase activity
ALPR1_RS00025	COG1595	DNA-templated transcription, initiation
ALPR1_RS00045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALPR1_RS00050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALPR1_RS00055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALPR1_RS00070	COG0668	transmembrane transport
ALPR1_RS00125	COG4946	Tricorn protease homolog
ALPR1_RS00125	COG0793	Belongs to the peptidase S41A family
ALPR1_RS00125	COG4946	Tricorn protease homolog
ALPR1_RS00125	COG0793	Belongs to the peptidase S41A family
ALPR1_RS00130	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALPR1_RS00135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALPR1_RS00170	COG4206	TonB-dependent receptor
ALPR1_RS00170	COG1629	transport
ALPR1_RS00180	COG0714	Associated with various cellular activities
ALPR1_RS00185	COG1187	pseudouridine synthase activity
ALPR1_RS00195	COG1473	amidohydrolase
ALPR1_RS00240	COG4771	TonB-dependent receptor
ALPR1_RS00270	COG1132	(ABC) transporter
ALPR1_RS00285	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALPR1_RS00290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALPR1_RS00305	COG4303	Ethanolamine ammonia lyase large subunit
ALPR1_RS00310	COG4302	ethanolamine ammonia-lyase activity
ALPR1_RS00370	COG1404	Belongs to the peptidase S8 family
ALPR1_RS00375	COG0698	ribose 5-phosphate isomerase
ALPR1_RS00380	COG0805	protein transport
ALPR1_RS00385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALPR1_RS00410	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALPR1_RS00415	COG2154	pterin-4-alpha-carbinolamine dehydratase
ALPR1_RS00425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALPR1_RS00455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALPR1_RS00460	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ALPR1_RS00475	COG0519	Catalyzes the synthesis of GMP from XMP
ALPR1_RS00480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALPR1_RS00485	COG0788	formyltetrahydrofolate deformylase activity
ALPR1_RS00490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALPR1_RS00500	COG1809	phosphosulfolactate synthase activity
ALPR1_RS00510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS00515	COG4464	protein tyrosine phosphatase activity
ALPR1_RS00525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALPR1_RS00540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALPR1_RS00575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALPR1_RS00580	COG0598	Magnesium transport protein CorA
ALPR1_RS00590	COG0157	Belongs to the NadC ModD family
ALPR1_RS00600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ALPR1_RS00625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALPR1_RS00625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALPR1_RS00630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALPR1_RS00665	COG2382	esterase
ALPR1_RS00685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ALPR1_RS00705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALPR1_RS00720	COG1233	COG1233 Phytoene dehydrogenase and related
ALPR1_RS00725	COG1595	DNA-templated transcription, initiation
ALPR1_RS00870	COG0156	8-amino-7-oxononanoate synthase activity
ALPR1_RS00920	COG2226	methyltransferase
ALPR1_RS00930	COG0352	thiamine-phosphate diphosphorylase activity
ALPR1_RS00975	COG0038	chloride channel
ALPR1_RS00980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALPR1_RS00985	COG0569	domain protein
ALPR1_RS00990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALPR1_RS00995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALPR1_RS01005	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ALPR1_RS01010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALPR1_RS01015	COG0596	Alpha beta hydrolase
ALPR1_RS01020	COG1956	GAF domain-containing protein
ALPR1_RS01025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALPR1_RS01025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALPR1_RS01040	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ALPR1_RS01075	COG2133	pyrroloquinoline quinone binding
ALPR1_RS01080	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS01085	COG0183	Belongs to the thiolase family
ALPR1_RS01095	COG1024	Enoyl-CoA hydratase
ALPR1_RS01095	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALPR1_RS01105	COG1022	Amp-dependent synthetase and ligase
ALPR1_RS01120	COG0445	tRNA wobble uridine modification
ALPR1_RS01125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALPR1_RS01135	COG0708	Exodeoxyribonuclease III
ALPR1_RS01150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALPR1_RS01155	COG2318	DinB family
ALPR1_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS01180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALPR1_RS01205	COG1012	belongs to the aldehyde dehydrogenase family
ALPR1_RS01210	COG0668	transmembrane transport
ALPR1_RS01220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALPR1_RS01225	COG0653	protein targeting
ALPR1_RS01235	COG1473	amidohydrolase
ALPR1_RS01265	COG0604	alcohol dehydrogenase
ALPR1_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS01265	COG3321	synthase
ALPR1_RS01275	COG1764	response to oxidative stress
ALPR1_RS01280	COG1846	Transcriptional regulator
ALPR1_RS01285	COG3118	belongs to the thioredoxin family
ALPR1_RS01285	COG0492	ferredoxin-NADP+ reductase activity
ALPR1_RS01290	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS01295	COG0583	DNA-binding transcription factor activity
ALPR1_RS01300	COG3015	lipoprotein NlpE involved in copper resistance
ALPR1_RS01350	COG4771	TonB-dependent receptor
ALPR1_RS01355	COG0702	epimerase
ALPR1_RS01365	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ALPR1_RS01375	COG1629	transport
ALPR1_RS01390	COG3119	arylsulfatase activity
ALPR1_RS01405	COG3119	arylsulfatase activity
ALPR1_RS01450	COG1187	pseudouridine synthase activity
ALPR1_RS01460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALPR1_RS01465	COG1845	cytochrome c oxidase, subunit III
ALPR1_RS01485	COG1704	LemA family
ALPR1_RS01495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ALPR1_RS01500	COG0303	'Molybdopterin
ALPR1_RS01505	COG0746	molybdenum cofactor guanylyltransferase activity
ALPR1_RS01515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ALPR1_RS01530	COG0315	cyclic pyranopterin monophosphate synthase activity
ALPR1_RS01535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALPR1_RS01550	COG1773	rubredoxin
ALPR1_RS01555	COG0243	molybdopterin cofactor binding
ALPR1_RS01560	COG2223	nitrite transmembrane transporter activity
ALPR1_RS01565	COG2197	response regulator
ALPR1_RS01580	COG2146	nitrite reductase [NAD(P)H] activity
ALPR1_RS01580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALPR1_RS01585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALPR1_RS01590	COG0105	UTP biosynthetic process
ALPR1_RS01595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ALPR1_RS01600	COG0545	Peptidyl-prolyl cis-trans isomerase
ALPR1_RS01605	COG0545	Peptidyl-prolyl cis-trans isomerase
ALPR1_RS01610	COG0545	Peptidyl-prolyl cis-trans isomerase
ALPR1_RS01630	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALPR1_RS01640	COG0590	tRNA wobble adenosine to inosine editing
ALPR1_RS01675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALPR1_RS01680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALPR1_RS01700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ALPR1_RS01705	COG0217	transcriptional regulatory protein
ALPR1_RS01710	COG1252	NADH dehydrogenase
ALPR1_RS01725	COG0067	glutamate synthase
ALPR1_RS01725	COG0069	glutamate synthase activity
ALPR1_RS01725	COG0070	glutamate synthase
ALPR1_RS01735	COG0629	single-stranded DNA binding
ALPR1_RS01745	COG0776	regulation of translation
ALPR1_RS01755	COG1530	ribonuclease E activity
ALPR1_RS01765	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS01780	COG4771	TonB-dependent receptor
ALPR1_RS01790	COG3119	arylsulfatase activity
ALPR1_RS01850	COG3119	arylsulfatase activity
ALPR1_RS01855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ALPR1_RS01865	COG5564	TIM-barrel signal transduction protein
ALPR1_RS01905	COG3292	Two component regulator propeller
ALPR1_RS01905	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS01905	COG2205	protein histidine kinase activity
ALPR1_RS01910	COG4771	TonB-dependent receptor
ALPR1_RS01925	COG3507	Belongs to the glycosyl hydrolase 43 family
ALPR1_RS01940	COG3250	beta-galactosidase activity
ALPR1_RS01965	COG0277	FAD linked oxidase domain protein
ALPR1_RS01990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALPR1_RS02000	COG1959	2 iron, 2 sulfur cluster binding
ALPR1_RS02005	COG0702	epimerase
ALPR1_RS02015	COG2318	DinB family
ALPR1_RS02040	COG2204	response regulator
ALPR1_RS02095	COG3852	Histidine kinase
ALPR1_RS02135	COG4585	Histidine kinase
ALPR1_RS02160	COG4946	Tricorn protease homolog
ALPR1_RS02160	COG1506	peptidase
ALPR1_RS02160	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS02165	COG0531	amino acid
ALPR1_RS02170	COG0405	Gamma-glutamyltransferase
ALPR1_RS02200	COG2345	Transcriptional regulator
ALPR1_RS02215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALPR1_RS02230	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALPR1_RS02290	COG1764	response to oxidative stress
ALPR1_RS02295	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ALPR1_RS02310	COG4948	Mandelate Racemase Muconate Lactonizing
ALPR1_RS02325	COG0019	diaminopimelate decarboxylase activity
ALPR1_RS02385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALPR1_RS02390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALPR1_RS02395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALPR1_RS02400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALPR1_RS02415	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS02420	COG3275	phosphorelay sensor kinase activity
ALPR1_RS02425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALPR1_RS02435	COG1611	Belongs to the LOG family
ALPR1_RS02455	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ALPR1_RS02465	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS02470	COG2738	Putative neutral zinc metallopeptidase
ALPR1_RS02480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ALPR1_RS02485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALPR1_RS02490	COG0297	glycogen (starch) synthase activity
ALPR1_RS02500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ALPR1_RS02520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALPR1_RS02540	COG1629	transport
ALPR1_RS02555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALPR1_RS02555	COG0515	serine threonine protein kinase
ALPR1_RS02565	COG3622	Belongs to the hyi family
ALPR1_RS02575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALPR1_RS02585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALPR1_RS02600	COG1104	cysteine desulfurase activity
ALPR1_RS02605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALPR1_RS02615	COG3956	TIGRFAM MazG family protein
ALPR1_RS02640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALPR1_RS02655	COG0004	ammonium transporteR
ALPR1_RS02660	COG0347	Belongs to the P(II) protein family
ALPR1_RS02670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALPR1_RS02675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALPR1_RS02685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALPR1_RS02690	COG0527	aspartate kinase activity
ALPR1_RS02710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALPR1_RS02725	COG0778	Nitroreductase
ALPR1_RS02770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALPR1_RS02785	COG0326	Molecular chaperone. Has ATPase activity
ALPR1_RS02810	COG1138	Cytochrome C-type biogenesis protein
ALPR1_RS02815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALPR1_RS02820	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALPR1_RS02845	COG2176	DNA-directed DNA polymerase activity
ALPR1_RS02860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALPR1_RS02865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALPR1_RS02880	COG1477	protein flavinylation
ALPR1_RS02885	COG2255	four-way junction helicase activity
ALPR1_RS02890	COG0363	glucosamine-6-phosphate deaminase activity
ALPR1_RS02895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ALPR1_RS02900	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ALPR1_RS02915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALPR1_RS02920	COG0572	uridine kinase
ALPR1_RS02930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALPR1_RS02970	COG4585	Histidine kinase
ALPR1_RS02980	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS02995	COG0423	glycine-tRNA ligase activity
ALPR1_RS03015	COG2137	regulation of response to DNA damage stimulus
ALPR1_RS03020	COG0149	triose-phosphate isomerase activity
ALPR1_RS03025	COG2264	protein methyltransferase activity
ALPR1_RS03035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ALPR1_RS03035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ALPR1_RS03040	COG1137	ATPase activity
ALPR1_RS03055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALPR1_RS03060	COG3844	kynureninase activity
ALPR1_RS03065	COG0662	Cupin 2, conserved barrel domain protein
ALPR1_RS03085	COG2890	protein-(glutamine-N5) methyltransferase activity
ALPR1_RS03090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALPR1_RS03090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALPR1_RS03100	COG0517	IMP dehydrogenase activity
ALPR1_RS03100	COG0516	GMP reductase activity
ALPR1_RS03110	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALPR1_RS03120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALPR1_RS03125	COG1959	2 iron, 2 sulfur cluster binding
ALPR1_RS03135	COG0175	sulfate reduction
ALPR1_RS03140	COG0175	sulfate reduction
ALPR1_RS03145	COG2895	sulfate adenylyltransferase (ATP) activity
ALPR1_RS03150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALPR1_RS03160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALPR1_RS03160	COG1648	precorrin-2 dehydrogenase activity
ALPR1_RS03170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALPR1_RS03185	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALPR1_RS03195	COG0791	NLP P60 protein
ALPR1_RS03200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALPR1_RS03220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALPR1_RS03225	COG4974	Belongs to the 'phage' integrase family
ALPR1_RS03240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALPR1_RS03245	COG0463	Glycosyl transferase, family 2
ALPR1_RS03260	COG0284	orotidine-5'-phosphate decarboxylase activity
ALPR1_RS03275	COG1054	Belongs to the UPF0176 family
ALPR1_RS03290	COG2197	response regulator
ALPR1_RS03295	COG4585	Histidine kinase
ALPR1_RS03310	COG0488	(ABC) transporter
ALPR1_RS03345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ALPR1_RS03355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ALPR1_RS03375	COG1160	GTP binding
ALPR1_RS03380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALPR1_RS03395	COG0330	HflC and HflK could
ALPR1_RS03400	COG0330	HflC and HflK could
ALPR1_RS03410	COG3119	arylsulfatase activity
ALPR1_RS03440	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS03460	COG2169	Transcriptional regulator
ALPR1_RS03480	COG2259	Doxx family
ALPR1_RS03485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALPR1_RS03490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALPR1_RS03495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALPR1_RS03500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALPR1_RS03505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALPR1_RS03510	COG3938	Belongs to the proline racemase family
ALPR1_RS03520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALPR1_RS03525	COG1917	Cupin 2, conserved barrel domain protein
ALPR1_RS03525	COG2207	Transcriptional regulator
ALPR1_RS03545	COG1131	(ABC) transporter
ALPR1_RS03565	COG4771	TonB-dependent receptor
ALPR1_RS03575	COG1595	DNA-templated transcription, initiation
ALPR1_RS03595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALPR1_RS03595	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ALPR1_RS03620	COG0335	large ribosomal subunit rRNA binding
ALPR1_RS03625	COG0336	Belongs to the RNA methyltransferase TrmD family
ALPR1_RS03630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALPR1_RS03635	COG0228	four-way junction DNA binding
ALPR1_RS03645	COG2827	Endonuclease containing a URI domain
ALPR1_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS03680	COG1917	Cupin 2, conserved barrel domain protein
ALPR1_RS03680	COG2207	Transcriptional regulator
ALPR1_RS03685	COG3386	PFAM SMP-30 Gluconolaconase
ALPR1_RS03695	COG1063	alcohol dehydrogenase
ALPR1_RS03700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ALPR1_RS03715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALPR1_RS03720	COG0596	Alpha beta hydrolase
ALPR1_RS03725	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALPR1_RS03730	COG1610	YqeY-like protein
ALPR1_RS03740	COG0512	Glutamine amidotransferase of anthranilate synthase
ALPR1_RS03750	COG1674	ftsk spoiiie
ALPR1_RS03755	COG0167	dihydroorotate dehydrogenase activity
ALPR1_RS03760	COG4974	Belongs to the 'phage' integrase family
ALPR1_RS03765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALPR1_RS03770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ALPR1_RS03775	COG2095	MarC family integral membrane protein
ALPR1_RS03780	COG0328	RNA-DNA hybrid ribonuclease activity
ALPR1_RS03800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALPR1_RS03805	COG2226	methyltransferase
ALPR1_RS03815	COG4221	oxidoreductase activity
ALPR1_RS03820	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ALPR1_RS03830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ALPR1_RS03845	COG0697	spore germination
ALPR1_RS03850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALPR1_RS03865	COG4589	Belongs to the CDS family
ALPR1_RS03870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALPR1_RS03875	COG0688	phosphatidylethanolamine metabolic process
ALPR1_RS03900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALPR1_RS03905	COG0612	Peptidase, M16
ALPR1_RS03910	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ALPR1_RS03915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALPR1_RS03925	COG1629	transport
ALPR1_RS03955	COG0567	Dehydrogenase, E1 component
ALPR1_RS03960	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALPR1_RS04025	COG0542	response to heat
ALPR1_RS04070	COG1506	peptidase
ALPR1_RS04070	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS04095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ALPR1_RS04105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALPR1_RS04115	COG0561	phosphatase activity
ALPR1_RS04145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALPR1_RS04155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALPR1_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS04195	COG0460	homoserine dehydrogenase
ALPR1_RS04195	COG0527	aspartate kinase activity
ALPR1_RS04200	COG0083	homoserine kinase activity
ALPR1_RS04205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ALPR1_RS04225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALPR1_RS04230	COG2133	pyrroloquinoline quinone binding
ALPR1_RS04240	COG0527	aspartate kinase activity
ALPR1_RS04245	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS04250	COG3001	Fructosamine kinase
ALPR1_RS04255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALPR1_RS04265	COG1162	GTPase activity
ALPR1_RS04275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALPR1_RS04290	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS04305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ALPR1_RS04310	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS04320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALPR1_RS04320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALPR1_RS04325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALPR1_RS04355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALPR1_RS04360	COG2885	chlorophyll binding
ALPR1_RS04380	COG0563	adenylate kinase activity
ALPR1_RS04385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALPR1_RS04390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALPR1_RS04395	COG0484	heat shock protein binding
ALPR1_RS04405	COG4152	abc transporter atp-binding protein
ALPR1_RS04410	COG1668	transmembrane transport
ALPR1_RS04415	COG0783	Belongs to the Dps family
ALPR1_RS04420	COG3852	Histidine kinase
ALPR1_RS04425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ALPR1_RS04435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ALPR1_RS04440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ALPR1_RS04445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALPR1_RS04450	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALPR1_RS04455	COG1805	sodium ion transport
ALPR1_RS04465	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALPR1_RS04470	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ALPR1_RS04485	COG0709	Synthesizes selenophosphate from selenide and ATP
ALPR1_RS04490	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ALPR1_RS04495	COG3118	belongs to the thioredoxin family
ALPR1_RS04505	COG0357	Ribosomal RNA small subunit methyltransferase G
ALPR1_RS04510	COG1595	DNA-templated transcription, initiation
ALPR1_RS04515	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS04520	COG0343	queuine tRNA-ribosyltransferase activity
ALPR1_RS04530	COG0697	spore germination
ALPR1_RS04545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALPR1_RS04550	COG0129	dihydroxy-acid dehydratase activity
ALPR1_RS04555	COG0028	Belongs to the TPP enzyme family
ALPR1_RS04565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALPR1_RS04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALPR1_RS04575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALPR1_RS04580	COG0066	3-isopropylmalate dehydratase activity
ALPR1_RS04610	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS04630	COG0248	Ppx GppA phosphatase
ALPR1_RS04635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALPR1_RS04645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALPR1_RS04680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ALPR1_RS04695	COG0463	Glycosyl transferase, family 2
ALPR1_RS04700	COG0463	Glycosyl transferase, family 2
ALPR1_RS04700	COG1216	Glycosyl transferase, family 2
ALPR1_RS04705	COG2226	methyltransferase
ALPR1_RS04725	COG0552	protein localization to endoplasmic reticulum
ALPR1_RS04730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALPR1_RS04735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALPR1_RS04740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALPR1_RS04745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALPR1_RS04750	COG0113	porphobilinogen synthase activity
ALPR1_RS04755	COG0004	ammonium transporteR
ALPR1_RS04775	COG0443	Heat shock 70 kDa protein
ALPR1_RS04785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALPR1_RS04805	COG1132	(ABC) transporter
ALPR1_RS04810	COG0101	tRNA pseudouridine synthase activity
ALPR1_RS04845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ALPR1_RS04875	COG1132	(ABC) transporter
ALPR1_RS04885	COG0254	rRNA binding
ALPR1_RS04895	COG0470	DNA polymerase III
ALPR1_RS04905	COG0189	ligase activity
ALPR1_RS04910	COG0181	hydroxymethylbilane synthase activity
ALPR1_RS04915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALPR1_RS04920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS04925	COG0733	neurotransmitter:sodium symporter activity
ALPR1_RS04965	COG4181	ATPase activity
ALPR1_RS04970	COG1136	(ABC) transporter
ALPR1_RS04970	COG0577	efflux transmembrane transporter activity
ALPR1_RS05000	COG2153	protein acetylation
ALPR1_RS05010	COG0658	competence protein
ALPR1_RS05010	COG2333	competence protein COMEC
ALPR1_RS05015	COG1024	Enoyl-CoA hydratase
ALPR1_RS05020	COG0514	ATP-dependent DNA helicase (RecQ)
ALPR1_RS05045	COG0009	L-threonylcarbamoyladenylate synthase
ALPR1_RS05050	COG0126	phosphoglycerate kinase activity
ALPR1_RS05060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALPR1_RS05065	COG0616	signal peptide processing
ALPR1_RS05075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ALPR1_RS05080	COG3011	Protein conserved in bacteria
ALPR1_RS05095	COG1053	succinate dehydrogenase
ALPR1_RS05100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALPR1_RS05125	COG3457	Alanine racemase
ALPR1_RS05160	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALPR1_RS05185	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS05190	COG0084	hydrolase, TatD family'
ALPR1_RS05195	COG0252	asparaginase activity
ALPR1_RS05210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALPR1_RS05215	COG0811	peptide transport
ALPR1_RS05235	COG2270	Major facilitator Superfamily
ALPR1_RS05240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALPR1_RS05240	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALPR1_RS05245	COG2814	Major facilitator Superfamily
ALPR1_RS05255	COG0017	Asparaginyl-tRNA synthetase
ALPR1_RS05310	COG3022	response to hydroperoxide
ALPR1_RS05325	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS05365	COG1846	Transcriptional regulator
ALPR1_RS05370	COG0386	Belongs to the glutathione peroxidase family
ALPR1_RS05380	COG2814	Major facilitator Superfamily
ALPR1_RS05385	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ALPR1_RS05405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALPR1_RS05425	COG2936	dipeptidyl-peptidase activity
ALPR1_RS05470	COG0385	Bile acid
ALPR1_RS05505	COG2311	Membrane
ALPR1_RS05550	COG0714	Associated with various cellular activities
ALPR1_RS05560	COG3119	arylsulfatase activity
ALPR1_RS05575	COG0668	transmembrane transport
ALPR1_RS05620	COG1556	Lactate utilization protein
ALPR1_RS05625	COG1139	Iron-sulfur cluster binding protein
ALPR1_RS05630	COG0247	lactate metabolic process
ALPR1_RS05640	COG2188	Transcriptional regulator
ALPR1_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS05645	COG3347	Dehydrogenase
ALPR1_RS05660	COG4952	isomerase
ALPR1_RS05665	COG3386	PFAM SMP-30 Gluconolaconase
ALPR1_RS05675	COG0668	transmembrane transport
ALPR1_RS05690	COG3347	Dehydrogenase
ALPR1_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS05695	COG1629	transport
ALPR1_RS05700	COG0702	epimerase
ALPR1_RS05735	COG3119	arylsulfatase activity
ALPR1_RS05745	COG0084	hydrolase, TatD family'
ALPR1_RS05755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALPR1_RS05775	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ALPR1_RS05785	COG2234	aminopeptidase activity
ALPR1_RS05790	COG0215	cysteine-tRNA ligase activity
ALPR1_RS05795	COG0138	bifunctional purine biosynthesis protein purh
ALPR1_RS05820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALPR1_RS05825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALPR1_RS05830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALPR1_RS05835	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS05860	COG3119	arylsulfatase activity
ALPR1_RS05870	COG3265	gluconokinase activity
ALPR1_RS05875	COG1228	amidohydrolase
ALPR1_RS05890	COG1472	Belongs to the glycosyl hydrolase 3 family
ALPR1_RS05895	COG2211	Major facilitator Superfamily
ALPR1_RS05905	COG1649	PFAM Uncharacterised BCR, COG1649
ALPR1_RS05915	COG1349	DNA-binding transcription factor activity
ALPR1_RS05925	COG1473	amidohydrolase
ALPR1_RS05930	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALPR1_RS05965	COG3119	arylsulfatase activity
ALPR1_RS06000	COG2010	Cytochrome c
ALPR1_RS06030	COG0346	lactoylglutathione lyase activity
ALPR1_RS06075	COG4774	siderophore transport
ALPR1_RS06095	COG0492	ferredoxin-NADP+ reductase activity
ALPR1_RS06100	COG0300	oxidoreductase activity
ALPR1_RS06130	COG1629	transport
ALPR1_RS06130	COG4206	TonB-dependent receptor
ALPR1_RS06165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALPR1_RS06170	COG0494	nUDIX hydrolase
ALPR1_RS06175	COG0009	L-threonylcarbamoyladenylate synthase
ALPR1_RS06185	COG0542	response to heat
ALPR1_RS06195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ALPR1_RS06195	COG1796	DNA polymerase
ALPR1_RS06210	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ALPR1_RS06215	COG0540	Belongs to the ATCase OTCase family
ALPR1_RS06225	COG1131	(ABC) transporter
ALPR1_RS06250	COG0539	negative regulation of cytoplasmic translation
ALPR1_RS06250	COG2183	response to ionizing radiation
ALPR1_RS06270	COG0437	4 iron, 4 sulfur cluster binding
ALPR1_RS06295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALPR1_RS06300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALPR1_RS06310	COG0109	protoheme IX farnesyltransferase activity
ALPR1_RS06315	COG1845	cytochrome c oxidase, subunit III
ALPR1_RS06320	COG1845	cytochrome c oxidase, subunit III
ALPR1_RS06335	COG2322	membrane
ALPR1_RS06345	COG5000	phosphorelay sensor kinase activity
ALPR1_RS06355	COG0300	oxidoreductase activity
ALPR1_RS06360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALPR1_RS06380	COG3360	Dodecin
ALPR1_RS06385	COG2315	Protein conserved in bacteria
ALPR1_RS06410	COG4106	trans-aconitate 2-methyltransferase activity
ALPR1_RS06420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALPR1_RS06425	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS06430	COG3275	phosphorelay sensor kinase activity
ALPR1_RS06440	COG0022	dehydrogenase e1 component
ALPR1_RS06440	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALPR1_RS06445	COG1012	belongs to the aldehyde dehydrogenase family
ALPR1_RS06450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALPR1_RS06460	COG0124	histidyl-tRNA synthetase
ALPR1_RS06475	COG0463	Glycosyl transferase, family 2
ALPR1_RS06490	COG4771	TonB-dependent receptor
ALPR1_RS06495	COG0561	phosphatase activity
ALPR1_RS06510	COG1446	asparaginase
ALPR1_RS06525	COG0517	IMP dehydrogenase activity
ALPR1_RS06525	COG0516	GMP reductase activity
ALPR1_RS06535	COG0193	aminoacyl-tRNA hydrolase activity
ALPR1_RS06540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALPR1_RS06545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALPR1_RS06570	COG0359	binds to the 23S rRNA
ALPR1_RS06575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALPR1_RS06580	COG0360	Binds together with S18 to 16S ribosomal RNA
ALPR1_RS06605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALPR1_RS06610	COG0681	Belongs to the peptidase S26 family
ALPR1_RS06615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALPR1_RS06625	COG1475	DNA binding
ALPR1_RS06630	COG1192	Involved in chromosome partitioning
ALPR1_RS06635	COG0706	membrane insertase activity
ALPR1_RS06640	COG0504	CTP synthase activity
ALPR1_RS06655	COG1595	DNA-templated transcription, initiation
ALPR1_RS06670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ALPR1_RS06670	COG0617	tRNA 3'-terminal CCA addition
ALPR1_RS06670	COG0517	IMP dehydrogenase activity
ALPR1_RS06685	COG1404	Belongs to the peptidase S8 family
ALPR1_RS06695	COG2884	Cell division ATP-binding protein ftsE
ALPR1_RS06705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALPR1_RS06720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALPR1_RS06730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALPR1_RS06730	COG0512	Glutamine amidotransferase of anthranilate synthase
ALPR1_RS06735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALPR1_RS06740	COG0134	indole-3-glycerol-phosphate synthase activity
ALPR1_RS06745	COG0135	phosphoribosylanthranilate isomerase activity
ALPR1_RS06750	COG0133	tryptophan synthase activity
ALPR1_RS06755	COG0159	tryptophan synthase activity
ALPR1_RS06760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ALPR1_RS06765	COG3186	Phenylalanine-4-hydroxylase
ALPR1_RS06775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALPR1_RS06780	COG0107	imidazoleglycerol-phosphate synthase activity
ALPR1_RS06785	COG0140	phosphoribosyl-ATP diphosphatase activity
ALPR1_RS06785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALPR1_RS06800	COG0667	Aldo Keto reductase
ALPR1_RS06810	COG1217	gtp-binding protein TYPA
ALPR1_RS06815	COG3537	Alpha-1,2-mannosidase
ALPR1_RS06820	COG2066	Belongs to the glutaminase family
ALPR1_RS06860	COG1012	belongs to the aldehyde dehydrogenase family
ALPR1_RS06875	COG0495	leucyl-tRNA aminoacylation
ALPR1_RS06880	COG1473	amidohydrolase
ALPR1_RS06890	COG0602	queuosine metabolic process
ALPR1_RS06895	COG2885	chlorophyll binding
ALPR1_RS06900	COG4771	TonB-dependent receptor
ALPR1_RS06925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALPR1_RS06935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALPR1_RS06940	COG0740	serine-type endopeptidase activity
ALPR1_RS06945	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALPR1_RS06955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALPR1_RS06965	COG1366	Belongs to the anti-sigma-factor antagonist family
ALPR1_RS06975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALPR1_RS07010	COG2217	Heavy metal translocating P-type atpase
ALPR1_RS07035	COG0348	domain, Protein
ALPR1_RS07050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALPR1_RS07055	COG2304	oxidoreductase activity
ALPR1_RS07075	COG1193	negative regulation of DNA recombination
ALPR1_RS07085	COG1131	(ABC) transporter
ALPR1_RS07090	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALPR1_RS07095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALPR1_RS07095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALPR1_RS07100	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALPR1_RS07105	COG1078	dGTPase activity
ALPR1_RS07110	COG2204	response regulator
ALPR1_RS07115	COG0802	atpase or kinase
ALPR1_RS07120	COG0686	Belongs to the AlaDH PNT family
ALPR1_RS07175	COG1538	Outer membrane efflux protein
ALPR1_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALPR1_RS07190	COG0481	GTPase activity
ALPR1_RS07200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALPR1_RS07220	COG2205	protein histidine kinase activity
ALPR1_RS07220	COG0784	Response regulator, receiver
ALPR1_RS07225	COG2204	response regulator
ALPR1_RS07265	COG0525	valine-tRNA ligase activity
ALPR1_RS07270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALPR1_RS07280	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALPR1_RS07340	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS07400	COG0577	efflux transmembrane transporter activity
ALPR1_RS07415	COG2207	Transcriptional regulator
ALPR1_RS07415	COG1917	Cupin 2, conserved barrel domain protein
ALPR1_RS07420	COG0024	Methionine aminopeptidase
ALPR1_RS07465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALPR1_RS07475	COG2827	Endonuclease containing a URI domain
ALPR1_RS07480	COG1136	(ABC) transporter
ALPR1_RS07485	COG0577	efflux transmembrane transporter activity
ALPR1_RS07485	COG1136	(ABC) transporter
ALPR1_RS07495	COG2272	Belongs to the type-B carboxylesterase lipase family
ALPR1_RS07500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALPR1_RS07505	COG1331	Highly conserved protein containing a thioredoxin domain
ALPR1_RS07515	COG1595	DNA-templated transcription, initiation
ALPR1_RS07530	COG0346	lactoylglutathione lyase activity
ALPR1_RS07535	COG1506	peptidase
ALPR1_RS07535	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS07535	COG4946	Tricorn protease homolog
ALPR1_RS07550	COG4771	TonB-dependent receptor
ALPR1_RS07555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ALPR1_RS07560	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS07565	COG5002	protein histidine kinase activity
ALPR1_RS07640	COG4771	TonB-dependent receptor
ALPR1_RS07685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALPR1_RS07695	COG2183	response to ionizing radiation
ALPR1_RS07700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALPR1_RS07715	COG3620	sequence-specific DNA binding
ALPR1_RS07770	COG2514	catechol 2,3-dioxygenase activity
ALPR1_RS07775	COG3661	Belongs to the glycosyl hydrolase 67 family
ALPR1_RS07815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALPR1_RS07820	COG1127	ABC transporter
ALPR1_RS07835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALPR1_RS07860	COG1774	PSP1 C-terminal conserved region
ALPR1_RS07865	COG0151	Belongs to the GarS family
ALPR1_RS07870	COG0514	ATP-dependent DNA helicase (RecQ)
ALPR1_RS07885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALPR1_RS07895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALPR1_RS07910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALPR1_RS07910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALPR1_RS07935	COG3258	Cytochrome c
ALPR1_RS07945	COG3239	Fatty acid desaturase
ALPR1_RS07950	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS07965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALPR1_RS07985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALPR1_RS07985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALPR1_RS07995	COG3852	Histidine kinase
ALPR1_RS08000	COG2204	response regulator
ALPR1_RS08010	COG0577	efflux transmembrane transporter activity
ALPR1_RS08010	COG1136	(ABC) transporter
ALPR1_RS08015	COG0577	efflux transmembrane transporter activity
ALPR1_RS08020	COG0577	efflux transmembrane transporter activity
ALPR1_RS08020	COG1136	(ABC) transporter
ALPR1_RS08055	COG0577	efflux transmembrane transporter activity
ALPR1_RS08060	COG3876	Protein conserved in bacteria
ALPR1_RS08075	COG0577	efflux transmembrane transporter activity
ALPR1_RS08080	COG1629	transport
ALPR1_RS08085	COG0702	epimerase
ALPR1_RS08110	COG3781	membrane
ALPR1_RS08115	COG1271	oxidase subunit
ALPR1_RS08145	COG0577	efflux transmembrane transporter activity
ALPR1_RS08145	COG1136	(ABC) transporter
ALPR1_RS08150	COG3781	membrane
ALPR1_RS08200	COG3119	arylsulfatase activity
ALPR1_RS08230	COG0577	efflux transmembrane transporter activity
ALPR1_RS08230	COG1136	(ABC) transporter
ALPR1_RS08235	COG0577	efflux transmembrane transporter activity
ALPR1_RS08245	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS08250	COG0577	efflux transmembrane transporter activity
ALPR1_RS08255	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALPR1_RS08255	COG1136	(ABC) transporter
ALPR1_RS08275	COG1573	uracil-dna glycosylase
ALPR1_RS08315	COG0714	Associated with various cellular activities
ALPR1_RS08340	COG1595	DNA-templated transcription, initiation
ALPR1_RS08360	COG4771	TonB-dependent receptor
ALPR1_RS08370	COG2205	protein histidine kinase activity
ALPR1_RS08370	COG3292	Two component regulator propeller
ALPR1_RS08370	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS08380	COG3119	arylsulfatase activity
ALPR1_RS08385	COG3119	arylsulfatase activity
ALPR1_RS08390	COG0534	Mate efflux family protein
ALPR1_RS08395	COG2318	DinB family
ALPR1_RS08415	COG0667	Aldo Keto reductase
ALPR1_RS08420	COG1063	alcohol dehydrogenase
ALPR1_RS08435	COG2382	esterase
ALPR1_RS08440	COG3507	Belongs to the glycosyl hydrolase 43 family
ALPR1_RS08440	COG3693	PFAM glycoside hydrolase, family 10
ALPR1_RS08440	COG2382	esterase
ALPR1_RS08445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALPR1_RS08450	COG2851	Citrate transporter
ALPR1_RS08510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALPR1_RS08515	COG4948	Mandelate Racemase Muconate Lactonizing
ALPR1_RS08520	COG2706	6-phosphogluconolactonase activity
ALPR1_RS08525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALPR1_RS08580	COG0671	phosphoesterase, PA-phosphatase related
ALPR1_RS08585	COG0408	coproporphyrinogen oxidase activity
ALPR1_RS08595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALPR1_RS08625	COG2151	metal-sulfur cluster biosynthetic enzyme
ALPR1_RS08630	COG2166	iron-sulfur cluster assembly
ALPR1_RS08635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALPR1_RS08640	COG0719	Fe-S assembly protein
ALPR1_RS08645	COG0396	ATPase activity
ALPR1_RS08650	COG0719	Fe-S assembly protein
ALPR1_RS08655	COG1522	sequence-specific DNA binding
ALPR1_RS08670	COG1506	peptidase
ALPR1_RS08670	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS08675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALPR1_RS08720	COG2244	polysaccharide biosynthetic process
ALPR1_RS08760	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS08775	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALPR1_RS08785	COG0489	protein tyrosine kinase activity
ALPR1_RS08800	COG1132	(ABC) transporter
ALPR1_RS08805	COG0297	glycogen (starch) synthase activity
ALPR1_RS08810	COG0367	asparagine synthase
ALPR1_RS08820	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS08825	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS08830	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS08835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ALPR1_RS08835	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS08865	COG0367	asparagine synthase
ALPR1_RS08880	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALPR1_RS08885	COG0277	FAD linked oxidase domain protein
ALPR1_RS08905	COG2089	acid synthase
ALPR1_RS08920	COG1083	cytidylyl-transferase
ALPR1_RS08985	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS08990	COG0463	Glycosyl transferase, family 2
ALPR1_RS09000	COG0456	acetyltransferase
ALPR1_RS09005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALPR1_RS09075	COG1442	glycosyl transferase family 8
ALPR1_RS09100	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS09110	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS09115	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS09185	COG4771	TonB-dependent receptor
ALPR1_RS09200	COG3119	arylsulfatase activity
ALPR1_RS09210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ALPR1_RS09225	COG2153	protein acetylation
ALPR1_RS09260	COG3254	rhamnose metabolic process
ALPR1_RS09265	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS09270	COG4447	cellulose binding
ALPR1_RS09275	COG3119	arylsulfatase activity
ALPR1_RS09290	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS09305	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS09315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALPR1_RS09335	COG0489	protein tyrosine kinase activity
ALPR1_RS09340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ALPR1_RS09350	COG0489	protein tyrosine kinase activity
ALPR1_RS09370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS09380	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ALPR1_RS09385	COG0471	metal ion transport
ALPR1_RS09385	COG3273	potassium ion transport
ALPR1_RS09390	COG0529	Catalyzes the synthesis of activated sulfate
ALPR1_RS09395	COG0175	sulfate reduction
ALPR1_RS09445	COG0110	maltose O-acetyltransferase activity
ALPR1_RS09465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ALPR1_RS09485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALPR1_RS09490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALPR1_RS09495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALPR1_RS09510	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ALPR1_RS09515	COG2176	DNA-directed DNA polymerase activity
ALPR1_RS09525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALPR1_RS09540	COG0667	Aldo Keto reductase
ALPR1_RS09550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ALPR1_RS09570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALPR1_RS09585	COG2321	neutral zinc metallopeptidase
ALPR1_RS09615	COG1201	RNA secondary structure unwinding
ALPR1_RS09640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ALPR1_RS09645	COG0488	(ABC) transporter
ALPR1_RS09670	COG2827	Endonuclease containing a URI domain
ALPR1_RS09690	COG0825	malonyl-CoA metabolic process
ALPR1_RS09695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALPR1_RS09710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALPR1_RS09730	COG0187	DNA topoisomerase II activity
ALPR1_RS09735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALPR1_RS09750	COG3273	potassium ion transport
ALPR1_RS09750	COG0471	metal ion transport
ALPR1_RS09770	COG0045	succinate-CoA ligase (ADP-forming) activity
ALPR1_RS09775	COG1136	(ABC) transporter
ALPR1_RS09780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALPR1_RS09790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALPR1_RS09795	COG1335	isochorismatase
ALPR1_RS09825	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ALPR1_RS09830	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS09845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS09850	COG0110	maltose O-acetyltransferase activity
ALPR1_RS09855	COG1312	Catalyzes the dehydration of D-mannonate
ALPR1_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS09865	COG1904	glucuronate isomerase
ALPR1_RS09870	COG1609	Transcriptional regulator
ALPR1_RS09880	COG4771	TonB-dependent receptor
ALPR1_RS09895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ALPR1_RS09895	COG0116	Belongs to the methyltransferase superfamily
ALPR1_RS09905	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS09910	COG2972	Histidine kinase
ALPR1_RS09925	COG1984	allophanate hydrolase subunit 2
ALPR1_RS09930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALPR1_RS09935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALPR1_RS09950	COG3852	Histidine kinase
ALPR1_RS09955	COG0784	Response regulator, receiver
ALPR1_RS09975	COG2204	response regulator
ALPR1_RS09980	COG2204	response regulator
ALPR1_RS09985	COG0783	Belongs to the Dps family
ALPR1_RS09995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALPR1_RS10000	COG1321	iron dependent repressor
ALPR1_RS10005	COG4771	TonB-dependent receptor
ALPR1_RS10015	COG2217	Heavy metal translocating P-type atpase
ALPR1_RS10045	COG2217	Heavy metal translocating P-type atpase
ALPR1_RS10100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALPR1_RS10170	COG3237	CsbD-like
ALPR1_RS10180	COG0534	Mate efflux family protein
ALPR1_RS10185	COG2814	Major facilitator Superfamily
ALPR1_RS10195	COG4807	Protein conserved in bacteria
ALPR1_RS10200	COG4895	conserved protein (DUF2196)
ALPR1_RS10225	COG1621	beta-fructofuranosidase activity
ALPR1_RS10230	COG1819	glycosyl
ALPR1_RS10255	COG2814	Major facilitator Superfamily
ALPR1_RS10270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALPR1_RS10275	COG0307	riboflavin synthase, alpha
ALPR1_RS10280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALPR1_RS10295	COG1528	Iron-storage protein
ALPR1_RS10310	COG0384	phenazine biosynthesis protein PhzF
ALPR1_RS10325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALPR1_RS10345	COG4783	chaperone-mediated protein folding
ALPR1_RS10350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALPR1_RS10355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALPR1_RS10365	COG0305	Participates in initiation and elongation during chromosome replication
ALPR1_RS10370	COG0604	alcohol dehydrogenase
ALPR1_RS10385	COG2086	electron transfer activity
ALPR1_RS10390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ALPR1_RS10400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ALPR1_RS10410	COG0564	pseudouridine synthase activity
ALPR1_RS10415	COG0482	sulfurtransferase activity
ALPR1_RS10435	COG0405	Gamma-glutamyltransferase
ALPR1_RS10465	COG1428	Deoxynucleoside kinase
ALPR1_RS10470	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALPR1_RS10530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALPR1_RS10535	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ALPR1_RS10555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALPR1_RS10575	COG1950	PFAM Membrane protein of
ALPR1_RS10590	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALPR1_RS10605	COG1360	Flagellar Motor Protein
ALPR1_RS10610	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS10620	COG1115	amino acid carrier protein
ALPR1_RS10625	COG1929	Belongs to the glycerate kinase type-1 family
ALPR1_RS10640	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS10655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALPR1_RS10665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALPR1_RS10670	COG3250	beta-galactosidase activity
ALPR1_RS10680	COG0668	transmembrane transport
ALPR1_RS10690	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ALPR1_RS10700	COG0385	Bile acid
ALPR1_RS10735	COG2307	Protein conserved in bacteria
ALPR1_RS10735	COG2308	Evidence 4 Homologs of previously reported genes of
ALPR1_RS10770	COG0154	amidase activity
ALPR1_RS10785	COG0577	efflux transmembrane transporter activity
ALPR1_RS10785	COG1136	(ABC) transporter
ALPR1_RS10815	COG0667	Aldo Keto reductase
ALPR1_RS10840	COG0577	efflux transmembrane transporter activity
ALPR1_RS10855	COG1090	epimerase
ALPR1_RS10875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALPR1_RS10885	COG1061	Type III restriction enzyme res subunit
ALPR1_RS10900	COG1196	nuclear chromosome segregation
ALPR1_RS10915	COG2852	Protein conserved in bacteria
ALPR1_RS10935	COG0791	NLP P60 protein
ALPR1_RS10945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ALPR1_RS10950	COG0804	urea catabolic process
ALPR1_RS10955	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS10965	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS10995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALPR1_RS11010	COG1473	amidohydrolase
ALPR1_RS11025	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS11040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALPR1_RS11090	COG2721	sulfolactate sulfo-lyase activity
ALPR1_RS11105	COG0450	alkyl hydroperoxide reductase
ALPR1_RS11120	COG0463	Glycosyl transferase, family 2
ALPR1_RS11130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALPR1_RS11160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALPR1_RS11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ALPR1_RS11170	COG0196	riboflavin kinase activity
ALPR1_RS11175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALPR1_RS11180	COG1968	undecaprenyl-diphosphatase activity
ALPR1_RS11190	COG2177	Part of the ABC transporter FtsEX involved in
ALPR1_RS11205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALPR1_RS11215	COG0288	reversible hydration of carbon dioxide
ALPR1_RS11220	COG0659	secondary active sulfate transmembrane transporter activity
ALPR1_RS11225	COG0165	Argininosuccinate lyase
ALPR1_RS11235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALPR1_RS11250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALPR1_RS11255	COG0137	argininosuccinate synthase activity
ALPR1_RS11265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALPR1_RS11275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ALPR1_RS11335	COG1643	Atp-dependent helicase
ALPR1_RS11340	COG2267	carboxylic ester hydrolase activity
ALPR1_RS11355	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS11375	COG3119	arylsulfatase activity
ALPR1_RS11390	COG3507	Belongs to the glycosyl hydrolase 43 family
ALPR1_RS11410	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS11435	COG1104	cysteine desulfurase activity
ALPR1_RS11445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ALPR1_RS11510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALPR1_RS11515	COG3590	peptidase
ALPR1_RS11535	COG0300	oxidoreductase activity
ALPR1_RS11540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALPR1_RS11570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALPR1_RS11590	COG2423	ornithine cyclodeaminase activity
ALPR1_RS11595	COG4206	TonB-dependent receptor
ALPR1_RS11600	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS11610	COG5285	phytanoyl-CoA dioxygenase
ALPR1_RS11625	COG0471	metal ion transport
ALPR1_RS11630	COG3275	phosphorelay sensor kinase activity
ALPR1_RS11640	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS11645	COG0662	Cupin 2, conserved barrel domain protein
ALPR1_RS11645	COG2207	Transcriptional regulator
ALPR1_RS11660	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS11705	COG1196	nuclear chromosome segregation
ALPR1_RS11710	COG1678	Uncharacterized ACR, COG1678
ALPR1_RS11720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ALPR1_RS11725	COG1196	nuclear chromosome segregation
ALPR1_RS11725	COG0741	lytic transglycosylase activity
ALPR1_RS11725	COG0739	heme binding
ALPR1_RS11730	COG0492	ferredoxin-NADP+ reductase activity
ALPR1_RS11735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALPR1_RS11740	COG1185	polyribonucleotide nucleotidyltransferase activity
ALPR1_RS11745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALPR1_RS11780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALPR1_RS11785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALPR1_RS11790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALPR1_RS11795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALPR1_RS11805	COG1629	transport
ALPR1_RS11805	COG4206	TonB-dependent receptor
ALPR1_RS11810	COG0579	oxidoreductase
ALPR1_RS11815	COG0069	glutamate synthase activity
ALPR1_RS11820	COG0429	hydrolase of the alpha beta-hydrolase fold
ALPR1_RS11830	COG2081	HI0933 family
ALPR1_RS11835	COG0433	COG0433 Predicted ATPase
ALPR1_RS11855	COG2171	N-acyltransferase activity
ALPR1_RS11865	COG1321	iron dependent repressor
ALPR1_RS11875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALPR1_RS11920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ALPR1_RS11985	COG4771	TonB-dependent receptor
ALPR1_RS12015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ALPR1_RS12020	COG3119	arylsulfatase activity
ALPR1_RS12025	COG0730	response to heat
ALPR1_RS12085	COG3501	Rhs element vgr protein
ALPR1_RS12120	COG2197	response regulator
ALPR1_RS12125	COG3119	arylsulfatase activity
ALPR1_RS12130	COG3119	arylsulfatase activity
ALPR1_RS12130	COG3408	Glycogen debranching enzyme
ALPR1_RS12135	COG2382	esterase
ALPR1_RS12135	COG3693	PFAM glycoside hydrolase, family 10
ALPR1_RS12170	COG0363	glucosamine-6-phosphate deaminase activity
ALPR1_RS12220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALPR1_RS12230	COG1063	alcohol dehydrogenase
ALPR1_RS12235	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS12240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALPR1_RS12255	COG0848	biopolymer transport protein
ALPR1_RS12260	COG0811	peptide transport
ALPR1_RS12295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALPR1_RS12340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALPR1_RS12360	COG0656	L-ascorbic acid biosynthetic process
ALPR1_RS12365	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS12370	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS12385	COG2824	Alkylphosphonate utilization operon protein PhnA
ALPR1_RS12390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ALPR1_RS12405	COG0484	heat shock protein binding
ALPR1_RS12425	COG1538	Outer membrane efflux protein
ALPR1_RS12445	COG2329	Antibiotic biosynthesis monooxygenase
ALPR1_RS12465	COG3291	Pkd domain containing protein
ALPR1_RS12470	COG3291	Pkd domain containing protein
ALPR1_RS12475	COG2115	Belongs to the xylose isomerase family
ALPR1_RS12495	COG1760	l-serine dehydratase
ALPR1_RS12510	COG0424	maF-like protein
ALPR1_RS12520	COG0439	Biotin carboxylase
ALPR1_RS12525	COG0156	8-amino-7-oxononanoate synthase activity
ALPR1_RS12550	COG1088	dTDP-glucose 4,6-dehydratase activity
ALPR1_RS12580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALPR1_RS12585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALPR1_RS12590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALPR1_RS12620	COG0598	Magnesium transport protein CorA
ALPR1_RS12630	COG2382	esterase
ALPR1_RS12635	COG3693	PFAM glycoside hydrolase, family 10
ALPR1_RS12635	COG3507	Belongs to the glycosyl hydrolase 43 family
ALPR1_RS12635	COG2382	esterase
ALPR1_RS12640	COG2382	esterase
ALPR1_RS12645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALPR1_RS12660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ALPR1_RS12670	COG2311	Membrane
ALPR1_RS12680	COG4145	pantothenate transmembrane transporter activity
ALPR1_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS12715	COG0436	Aminotransferase
ALPR1_RS12720	COG0010	Belongs to the arginase family
ALPR1_RS12725	COG0018	arginyl-trna synthetase
ALPR1_RS12730	COG0386	Belongs to the glutathione peroxidase family
ALPR1_RS12735	COG1575	Belongs to the MenA family. Type 1 subfamily
ALPR1_RS12740	COG0589	response to stress
ALPR1_RS12750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALPR1_RS12755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALPR1_RS12760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALPR1_RS12765	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ALPR1_RS12765	COG0131	Imidazoleglycerol-phosphate dehydratase
ALPR1_RS12775	COG0463	Glycosyl transferase, family 2
ALPR1_RS12785	COG3876	Protein conserved in bacteria
ALPR1_RS12790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALPR1_RS12800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ALPR1_RS12805	COG0300	oxidoreductase activity
ALPR1_RS12810	COG1058	Belongs to the CinA family
ALPR1_RS12810	COG1546	Belongs to the CinA family
ALPR1_RS12815	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALPR1_RS12820	COG0784	Response regulator, receiver
ALPR1_RS12820	COG2205	protein histidine kinase activity
ALPR1_RS12840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALPR1_RS12840	COG1703	isobutyryl-CoA mutase activity
ALPR1_RS12840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALPR1_RS12845	COG0427	acetyl-CoA hydrolase
ALPR1_RS12850	COG2814	Major facilitator Superfamily
ALPR1_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALPR1_RS12865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALPR1_RS12870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALPR1_RS12875	COG2239	Acts as a magnesium transporter
ALPR1_RS12880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALPR1_RS12885	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALPR1_RS12895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALPR1_RS12900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALPR1_RS12905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALPR1_RS12910	COG0511	ligase activity, forming carbon-carbon bonds
ALPR1_RS12915	COG0439	Biotin carboxylase
ALPR1_RS12955	COG1404	Belongs to the peptidase S8 family
ALPR1_RS12960	COG2326	polyphosphate kinase activity
ALPR1_RS12990	COG2204	response regulator
ALPR1_RS13005	COG0022	dehydrogenase e1 component
ALPR1_RS13010	COG0686	Belongs to the AlaDH PNT family
ALPR1_RS13030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALPR1_RS13035	COG2363	Small membrane protein
ALPR1_RS13040	COG2027	D-alanyl-D-alanine carboxypeptidase
ALPR1_RS13050	COG1619	proteins homologs of microcin C7 resistance protein MccF
ALPR1_RS13065	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALPR1_RS13070	COG0739	heme binding
ALPR1_RS13075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALPR1_RS13080	COG3959	Transketolase, thiamine diphosphate binding domain
ALPR1_RS13085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALPR1_RS13130	COG1063	alcohol dehydrogenase
ALPR1_RS13135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALPR1_RS13220	COG4206	TonB-dependent receptor
ALPR1_RS13240	COG0183	Belongs to the thiolase family
ALPR1_RS13250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALPR1_RS13260	COG1234	tRNA 3'-trailer cleavage
ALPR1_RS13265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ALPR1_RS13270	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS13275	COG0577	efflux transmembrane transporter activity
ALPR1_RS13275	COG1136	(ABC) transporter
ALPR1_RS13295	COG0758	DNA mediated transformation
ALPR1_RS13295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALPR1_RS13305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALPR1_RS13315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ALPR1_RS13320	COG0646	methionine synthase
ALPR1_RS13320	COG1410	methionine synthase
ALPR1_RS13325	COG1410	methionine synthase
ALPR1_RS13325	COG0646	methionine synthase
ALPR1_RS13335	COG3850	Histidine kinase
ALPR1_RS13335	COG3437	response regulator, receiver
ALPR1_RS13335	COG4999	Histidine kinase
ALPR1_RS13335	COG2205	protein histidine kinase activity
ALPR1_RS13340	COG0393	Putative heavy-metal-binding
ALPR1_RS13365	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALPR1_RS13380	COG0791	NLP P60 protein
ALPR1_RS13380	COG1388	LysM domain
ALPR1_RS13385	COG1030	water channel activity
ALPR1_RS13400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALPR1_RS13410	COG1136	(ABC) transporter
ALPR1_RS13415	COG2096	Adenosyltransferase
ALPR1_RS13420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALPR1_RS13430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ALPR1_RS13435	COG2814	Major facilitator Superfamily
ALPR1_RS13445	COG0534	Mate efflux family protein
ALPR1_RS13455	COG1522	sequence-specific DNA binding
ALPR1_RS13475	COG0730	response to heat
ALPR1_RS13485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALPR1_RS13505	COG4771	TonB-dependent receptor
ALPR1_RS13550	COG1770	oligopeptidase
ALPR1_RS13555	COG1803	Methylglyoxal synthase
ALPR1_RS13560	COG0205	6-phosphofructokinase activity
ALPR1_RS13575	COG3852	Histidine kinase
ALPR1_RS13580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALPR1_RS13590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALPR1_RS13590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALPR1_RS13595	COG0358	DNA primase activity
ALPR1_RS13600	COG0489	protein tyrosine kinase activity
ALPR1_RS13605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ALPR1_RS13615	COG0768	penicillin binding
ALPR1_RS13625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALPR1_RS13635	COG1011	Hydrolase
ALPR1_RS13695	COG2205	protein histidine kinase activity
ALPR1_RS13700	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS13750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALPR1_RS13775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALPR1_RS13780	COG1115	amino acid carrier protein
ALPR1_RS13800	COG1309	transcriptional regulator
ALPR1_RS13805	COG0628	permease
ALPR1_RS13820	COG2205	protein histidine kinase activity
ALPR1_RS13820	COG2198	Histidine kinase
ALPR1_RS13820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALPR1_RS13820	COG0784	Response regulator, receiver
ALPR1_RS13825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALPR1_RS13835	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS13845	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALPR1_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS13860	COG0738	Major facilitator superfamily
ALPR1_RS13870	COG0657	acetylesterase activity
ALPR1_RS13870	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS13880	COG1132	(ABC) transporter
ALPR1_RS13890	COG3321	synthase
ALPR1_RS13890	COG0604	alcohol dehydrogenase
ALPR1_RS13925	COG2382	esterase
ALPR1_RS13935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ALPR1_RS13955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALPR1_RS13965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALPR1_RS13975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ALPR1_RS13990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALPR1_RS13995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALPR1_RS14000	COG2204	response regulator
ALPR1_RS14030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALPR1_RS14035	COG0459	protein refolding
ALPR1_RS14040	COG2201	protein-glutamate methylesterase activity
ALPR1_RS14065	COG2388	GCN5-related N-acetyl-transferase
ALPR1_RS14110	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ALPR1_RS14115	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ALPR1_RS14130	COG2080	2 iron, 2 sulfur cluster binding
ALPR1_RS14135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALPR1_RS14135	COG2010	Cytochrome c
ALPR1_RS14235	COG0629	single-stranded DNA binding
ALPR1_RS14265	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS14265	COG0657	acetylesterase activity
ALPR1_RS14270	COG3046	protein related to deoxyribodipyrimidine photolyase
ALPR1_RS14280	COG0415	Belongs to the DNA photolyase family
ALPR1_RS14295	COG0629	single-stranded DNA binding
ALPR1_RS14305	COG0667	Aldo Keto reductase
ALPR1_RS14310	COG0205	6-phosphofructokinase activity
ALPR1_RS14320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALPR1_RS14325	COG2201	protein-glutamate methylesterase activity
ALPR1_RS14340	COG0321	lipoyl(octanoyl) transferase activity
ALPR1_RS14340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ALPR1_RS14345	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ALPR1_RS14350	COG0469	pyruvate kinase activity
ALPR1_RS14360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALPR1_RS14365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALPR1_RS14370	COG0571	ribonuclease III activity
ALPR1_RS14375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALPR1_RS14375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ALPR1_RS14380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALPR1_RS14385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALPR1_RS14415	COG0339	signal peptide processing
ALPR1_RS14420	COG0628	permease
ALPR1_RS14430	COG2205	protein histidine kinase activity
ALPR1_RS14430	COG3850	Histidine kinase
ALPR1_RS14430	COG3437	response regulator, receiver
ALPR1_RS14430	COG4999	Histidine kinase
ALPR1_RS14435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALPR1_RS14440	COG2031	fatty acid transporter
ALPR1_RS14445	COG2205	protein histidine kinase activity
ALPR1_RS14455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALPR1_RS14465	COG0628	permease
ALPR1_RS14470	COG0012	GTP binding
ALPR1_RS14485	COG0488	(ABC) transporter
ALPR1_RS14505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALPR1_RS14520	COG2135	peptidase activity
ALPR1_RS14525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALPR1_RS14545	COG1940	carbohydrate kinase activity
ALPR1_RS14560	COG3119	arylsulfatase activity
ALPR1_RS14565	COG0445	tRNA wobble uridine modification
ALPR1_RS14580	COG4771	TonB-dependent receptor
ALPR1_RS14590	COG4771	TonB-dependent receptor
ALPR1_RS14600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALPR1_RS14605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ALPR1_RS14610	COG1597	lipid kinase activity
ALPR1_RS14610	COG1803	Methylglyoxal synthase
ALPR1_RS14615	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS14635	COG0577	efflux transmembrane transporter activity
ALPR1_RS14655	COG1663	tetraacyldisaccharide 4'-kinase activity
ALPR1_RS14660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALPR1_RS14675	COG0588	phosphoglycerate mutase activity
ALPR1_RS14680	COG2050	protein possibly involved in aromatic compounds catabolism
ALPR1_RS14690	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ALPR1_RS14705	COG0583	DNA-binding transcription factor activity
ALPR1_RS14710	COG2986	histidine ammonia-lyase
ALPR1_RS14720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ALPR1_RS14730	COG0668	transmembrane transport
ALPR1_RS14740	COG0277	FAD linked oxidase domain protein
ALPR1_RS14740	COG0247	lactate metabolic process
ALPR1_RS14745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ALPR1_RS14760	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ALPR1_RS14760	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ALPR1_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS14770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALPR1_RS14780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ALPR1_RS14785	COG0346	lactoylglutathione lyase activity
ALPR1_RS14790	COG0316	Belongs to the HesB IscA family
ALPR1_RS14795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ALPR1_RS14800	COG2045	Belongs to the ComB family
ALPR1_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS14810	COG3119	arylsulfatase activity
ALPR1_RS14820	COG1694	Mazg nucleotide pyrophosphohydrolase
ALPR1_RS14825	COG2095	MarC family integral membrane protein
ALPR1_RS14835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALPR1_RS14850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALPR1_RS14860	COG1119	ATPase activity
ALPR1_RS14865	COG3119	arylsulfatase activity
ALPR1_RS14870	COG1490	D-aminoacyl-tRNA deacylase activity
ALPR1_RS14875	COG0702	epimerase
ALPR1_RS14895	COG0316	Belongs to the HesB IscA family
ALPR1_RS14955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALPR1_RS14960	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALPR1_RS14970	COG2235	arginine
ALPR1_RS14980	COG2204	response regulator
ALPR1_RS14985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALPR1_RS14995	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALPR1_RS15000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALPR1_RS15010	COG0077	Prephenate dehydratase
ALPR1_RS15010	COG1605	Chorismate mutase
ALPR1_RS15015	COG0436	Aminotransferase
ALPR1_RS15020	COG0287	Prephenate dehydrogenase
ALPR1_RS15035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ALPR1_RS15090	COG0515	serine threonine protein kinase
ALPR1_RS15115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ALPR1_RS15120	COG2808	Putative FMN-binding domain
ALPR1_RS15145	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS15190	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS15200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALPR1_RS15210	COG1054	Belongs to the UPF0176 family
ALPR1_RS15230	COG1555	photosystem II stabilization
ALPR1_RS15235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALPR1_RS15245	COG4864	UPF0365 protein
ALPR1_RS15255	COG0442	prolyl-tRNA aminoacylation
ALPR1_RS15270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALPR1_RS15285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALPR1_RS15290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ALPR1_RS15305	COG0156	8-amino-7-oxononanoate synthase activity
ALPR1_RS15310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS15335	COG1393	Belongs to the ArsC family
ALPR1_RS15345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALPR1_RS15355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALPR1_RS15355	COG0519	Catalyzes the synthesis of GMP from XMP
ALPR1_RS15375	COG1760	l-serine dehydratase
ALPR1_RS15415	COG0302	gtp cyclohydrolase
ALPR1_RS15440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALPR1_RS15445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALPR1_RS15450	COG3153	acetyltransferase
ALPR1_RS15450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALPR1_RS15455	COG3264	Mechanosensitive ion channel
ALPR1_RS15455	COG1511	domain protein
ALPR1_RS15475	COG0251	oxidation-reduction process
ALPR1_RS15480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALPR1_RS15495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALPR1_RS15520	COG5002	protein histidine kinase activity
ALPR1_RS15535	COG0587	DNA-directed DNA polymerase activity
ALPR1_RS15580	COG2116	formate transmembrane transporter activity
ALPR1_RS15595	COG2885	chlorophyll binding
ALPR1_RS15595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ALPR1_RS15630	COG1741	Belongs to the pirin family
ALPR1_RS15635	COG4977	sequence-specific DNA binding
ALPR1_RS15635	COG1917	Cupin 2, conserved barrel domain protein
ALPR1_RS15645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ALPR1_RS15685	COG5002	protein histidine kinase activity
ALPR1_RS15690	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS15710	COG2308	Evidence 4 Homologs of previously reported genes of
ALPR1_RS15715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ALPR1_RS15720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALPR1_RS15720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALPR1_RS15730	COG3119	arylsulfatase activity
ALPR1_RS15740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALPR1_RS15745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALPR1_RS15750	COG1570	exodeoxyribonuclease VII activity
ALPR1_RS15810	COG3153	acetyltransferase
ALPR1_RS15825	COG1266	CAAX protease self-immunity
ALPR1_RS15870	COG1917	Cupin 2, conserved barrel domain protein
ALPR1_RS15870	COG4977	sequence-specific DNA binding
ALPR1_RS15905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ALPR1_RS15910	COG2819	hydrolase of the alpha beta superfamily
ALPR1_RS15925	COG2423	ornithine cyclodeaminase activity
ALPR1_RS15940	COG1595	DNA-templated transcription, initiation
ALPR1_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS15955	COG0702	epimerase
ALPR1_RS15975	COG0656	L-ascorbic acid biosynthetic process
ALPR1_RS15985	COG3401	FG-GAP repeat protein
ALPR1_RS16055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALPR1_RS16060	COG3119	arylsulfatase activity
ALPR1_RS16065	COG0667	Aldo Keto reductase
ALPR1_RS16070	COG1063	alcohol dehydrogenase
ALPR1_RS16075	COG1082	Xylose isomerase domain protein TIM barrel
ALPR1_RS16080	COG3254	rhamnose metabolic process
ALPR1_RS16120	COG2354	Protein conserved in bacteria
ALPR1_RS16130	COG2610	gluconate transmembrane transporter activity
ALPR1_RS16135	COG1649	PFAM Uncharacterised BCR, COG1649
ALPR1_RS16135	COG0726	polysaccharide deacetylase
ALPR1_RS16140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ALPR1_RS16145	COG1704	LemA family
ALPR1_RS16155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ALPR1_RS16160	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS16175	COG2814	Major facilitator Superfamily
ALPR1_RS16180	COG0513	Belongs to the DEAD box helicase family
ALPR1_RS16185	COG3119	arylsulfatase activity
ALPR1_RS16195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALPR1_RS16200	COG4106	trans-aconitate 2-methyltransferase activity
ALPR1_RS16215	COG4948	Mandelate Racemase Muconate Lactonizing
ALPR1_RS16225	COG4948	Mandelate Racemase Muconate Lactonizing
ALPR1_RS16240	COG4771	TonB-dependent receptor
ALPR1_RS16255	COG5505	Protein of unknown function (DUF819)
ALPR1_RS16280	COG0473	3-isopropylmalate dehydrogenase activity
ALPR1_RS16285	COG1024	Enoyl-CoA hydratase
ALPR1_RS16310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALPR1_RS16315	COG0154	amidase activity
ALPR1_RS16320	COG0791	NLP P60 protein
ALPR1_RS16320	COG1388	LysM domain
ALPR1_RS16330	COG0281	malic enzyme
ALPR1_RS16330	COG0280	phosphate acetyltransferase
ALPR1_RS16335	COG0632	four-way junction helicase activity
ALPR1_RS16345	COG0509	glycine decarboxylation via glycine cleavage system
ALPR1_RS16365	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ALPR1_RS16370	COG1561	YicC-like family, N-terminal region
ALPR1_RS16380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALPR1_RS16385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALPR1_RS16390	COG1183	phosphatidylcholine synthase activity
ALPR1_RS16410	COG1216	Glycosyl transferase, family 2
ALPR1_RS16425	COG1739	Uncharacterized protein family UPF0029
ALPR1_RS16435	COG1757	Na H antiporter
ALPR1_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS16490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALPR1_RS16500	COG0799	negative regulation of ribosome biogenesis
ALPR1_RS16505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALPR1_RS16525	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALPR1_RS16540	COG5002	protein histidine kinase activity
ALPR1_RS16570	COG2382	esterase
ALPR1_RS16580	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS16580	COG1506	peptidase
ALPR1_RS16610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALPR1_RS16645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALPR1_RS16650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALPR1_RS16660	COG0415	Belongs to the DNA photolyase family
ALPR1_RS16695	COG1288	antiporter activity
ALPR1_RS16700	COG0626	cystathionine gamma-synthase activity
ALPR1_RS16735	COG1695	Transcriptional regulator
ALPR1_RS16745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALPR1_RS16755	COG1595	DNA-templated transcription, initiation
ALPR1_RS16790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ALPR1_RS16815	COG0288	reversible hydration of carbon dioxide
ALPR1_RS16845	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS16865	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS16870	COG2972	Histidine kinase
ALPR1_RS16875	COG1131	(ABC) transporter
ALPR1_RS16915	COG2204	response regulator
ALPR1_RS16920	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS16960	COG1476	TRANSCRIPTIONal
ALPR1_RS16965	COG0004	ammonium transporteR
ALPR1_RS16970	COG3511	phospholipase C
ALPR1_RS16985	COG0436	Aminotransferase
ALPR1_RS17010	COG3119	arylsulfatase activity
ALPR1_RS17015	COG3119	arylsulfatase activity
ALPR1_RS17020	COG3119	arylsulfatase activity
ALPR1_RS17035	COG3119	arylsulfatase activity
ALPR1_RS17040	COG3842	ATPase activity
ALPR1_RS17060	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ALPR1_RS17120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALPR1_RS17125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALPR1_RS17155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALPR1_RS17160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ALPR1_RS17185	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS17190	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS17210	COG0659	secondary active sulfate transmembrane transporter activity
ALPR1_RS17225	COG0071	Belongs to the small heat shock protein (HSP20) family
ALPR1_RS17235	COG1196	nuclear chromosome segregation
ALPR1_RS17235	COG3264	Mechanosensitive ion channel
ALPR1_RS17240	COG1278	Cold shock
ALPR1_RS17245	COG0588	phosphoglycerate mutase activity
ALPR1_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS17255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALPR1_RS17260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALPR1_RS17270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ALPR1_RS17275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALPR1_RS17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALPR1_RS17310	COG1120	ATPase activity
ALPR1_RS17315	COG1846	Transcriptional regulator
ALPR1_RS17320	COG0492	ferredoxin-NADP+ reductase activity
ALPR1_RS17325	COG0633	Ferredoxin
ALPR1_RS17365	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALPR1_RS17365	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALPR1_RS17370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALPR1_RS17375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALPR1_RS17385	COG1703	isobutyryl-CoA mutase activity
ALPR1_RS17395	COG1981	membrane
ALPR1_RS17400	COG1999	signal sequence binding
ALPR1_RS17430	COG1136	(ABC) transporter
ALPR1_RS17435	COG3437	response regulator, receiver
ALPR1_RS17435	COG4999	Histidine kinase
ALPR1_RS17435	COG3850	Histidine kinase
ALPR1_RS17435	COG2205	protein histidine kinase activity
ALPR1_RS17440	COG2205	protein histidine kinase activity
ALPR1_RS17445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALPR1_RS17455	COG0488	(ABC) transporter
ALPR1_RS17475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALPR1_RS17485	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS17500	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS17510	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ALPR1_RS17515	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS17525	COG0246	Mannitol dehydrogenase
ALPR1_RS17540	COG1418	mRNA catabolic process
ALPR1_RS17565	COG2003	Belongs to the UPF0758 family
ALPR1_RS17570	COG0268	Binds directly to 16S ribosomal RNA
ALPR1_RS17590	COG1228	amidohydrolase
ALPR1_RS17605	COG0604	alcohol dehydrogenase
ALPR1_RS17610	COG1733	regulation of RNA biosynthetic process
ALPR1_RS17620	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ALPR1_RS17665	COG0436	Aminotransferase
ALPR1_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS17710	COG0488	(ABC) transporter
ALPR1_RS17725	COG3279	Response regulator of the LytR AlgR family
ALPR1_RS17730	COG3275	phosphorelay sensor kinase activity
ALPR1_RS17740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALPR1_RS17745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALPR1_RS17750	COG1136	(ABC) transporter
ALPR1_RS17750	COG0577	efflux transmembrane transporter activity
ALPR1_RS17755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALPR1_RS17765	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS17770	COG5002	protein histidine kinase activity
ALPR1_RS17775	COG0564	pseudouridine synthase activity
ALPR1_RS17785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALPR1_RS17790	COG0052	Belongs to the universal ribosomal protein uS2 family
ALPR1_RS17795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALPR1_RS17800	COG0006	proline dipeptidase activity
ALPR1_RS17805	COG0612	Peptidase, M16
ALPR1_RS17815	COG0791	NLP P60 protein
ALPR1_RS17815	COG3103	Sh3 type 3 domain protein
ALPR1_RS17815	COG1388	LysM domain
ALPR1_RS17830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALPR1_RS17840	COG1408	metallophosphoesterase
ALPR1_RS17855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALPR1_RS17865	COG1538	Outer membrane efflux protein
ALPR1_RS17870	COG1131	(ABC) transporter
ALPR1_RS17890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALPR1_RS17900	COG0584	glycerophosphoryl diester phosphodiesterase
ALPR1_RS17920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALPR1_RS17935	COG1012	belongs to the aldehyde dehydrogenase family
ALPR1_RS17940	COG1011	Hydrolase
ALPR1_RS17960	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ALPR1_RS17990	COG1082	Xylose isomerase domain protein TIM barrel
ALPR1_RS17995	COG2211	Major facilitator Superfamily
ALPR1_RS18000	COG0673	inositol 2-dehydrogenase activity
ALPR1_RS18010	COG4654	Cytochrome c, class I
ALPR1_RS18060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALPR1_RS18065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALPR1_RS18075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALPR1_RS18080	COG0242	peptide deformylase activity
ALPR1_RS18085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALPR1_RS18095	COG0793	Belongs to the peptidase S41A family
ALPR1_RS18100	COG0346	lactoylglutathione lyase activity
ALPR1_RS18135	COG1012	belongs to the aldehyde dehydrogenase family
ALPR1_RS18175	COG0792	nuclease activity
ALPR1_RS18180	COG0321	lipoyl(octanoyl) transferase activity
ALPR1_RS18195	COG0557	exoribonuclease II activity
ALPR1_RS18210	COG4447	cellulose binding
ALPR1_RS18215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ALPR1_RS18220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALPR1_RS18230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALPR1_RS18230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALPR1_RS18270	COG1214	PFAM Peptidase M22, glycoprotease
ALPR1_RS18280	COG0594	ribonuclease P activity
ALPR1_RS18285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ALPR1_RS18295	COG0612	Peptidase, M16
ALPR1_RS18305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALPR1_RS18320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALPR1_RS18330	COG0022	dehydrogenase e1 component
ALPR1_RS18375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALPR1_RS18380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALPR1_RS18385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALPR1_RS18390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALPR1_RS18395	COG0420	3'-5' exonuclease activity
ALPR1_RS18400	COG0419	ATPase involved in DNA repair
ALPR1_RS18410	COG0346	lactoylglutathione lyase activity
ALPR1_RS18415	COG2353	YceI-like domain
ALPR1_RS18425	COG0596	Alpha beta hydrolase
ALPR1_RS18430	COG1228	amidohydrolase
ALPR1_RS18440	COG0497	DNA recombination
ALPR1_RS18485	COG0039	L-malate dehydrogenase activity
ALPR1_RS18495	COG0668	transmembrane transport
ALPR1_RS18530	COG1045	serine acetyltransferase
ALPR1_RS18545	COG0148	phosphopyruvate hydratase activity
ALPR1_RS18550	COG0505	Belongs to the CarA family
ALPR1_RS18555	COG0203	ribosomal protein L17
ALPR1_RS18560	COG0202	RNA polymerase activity
ALPR1_RS18565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALPR1_RS18570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALPR1_RS18575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALPR1_RS18580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALPR1_RS18590	COG0201	protein transport
ALPR1_RS18595	COG0200	Binds to the 23S rRNA
ALPR1_RS18600	COG1841	ribosomal large subunit assembly
ALPR1_RS18605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALPR1_RS18615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALPR1_RS18620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALPR1_RS18625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALPR1_RS18630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALPR1_RS18635	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALPR1_RS18640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALPR1_RS18645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALPR1_RS18650	COG0255	Belongs to the universal ribosomal protein uL29 family
ALPR1_RS18655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALPR1_RS18660	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALPR1_RS18665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALPR1_RS18670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALPR1_RS18675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALPR1_RS18680	COG0089	rRNA binding
ALPR1_RS18685	COG0088	Forms part of the polypeptide exit tunnel
ALPR1_RS18690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALPR1_RS18695	COG0051	transcription antitermination factor activity, RNA binding
ALPR1_RS18700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALPR1_RS18705	COG0049	tRNA binding
ALPR1_RS18710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALPR1_RS18720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALPR1_RS18725	COG0085	RNA polymerase activity
ALPR1_RS18730	COG0222	ribosome binding
ALPR1_RS18735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALPR1_RS18740	COG0081	regulation of translation
ALPR1_RS18745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALPR1_RS18790	COG4770	biotin carboxylase activity
ALPR1_RS18795	COG0528	UMP kinase activity
ALPR1_RS18800	COG0233	cytoplasmic translational termination
ALPR1_RS18820	COG0702	epimerase
ALPR1_RS18825	COG4771	TonB-dependent receptor
ALPR1_RS18850	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ALPR1_RS18855	COG3023	N-Acetylmuramoyl-L-alanine amidase
ALPR1_RS18860	COG3387	PFAM Glycoside hydrolase 15-related
ALPR1_RS18870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALPR1_RS18875	COG0194	GDP metabolic process
ALPR1_RS18885	COG1595	DNA-templated transcription, initiation
ALPR1_RS18905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALPR1_RS18915	COG0129	dihydroxy-acid dehydratase activity
ALPR1_RS18920	COG0300	oxidoreductase activity
ALPR1_RS18930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALPR1_RS18985	COG3119	arylsulfatase activity
ALPR1_RS18990	COG3119	arylsulfatase activity
ALPR1_RS18995	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALPR1_RS19025	COG0346	lactoylglutathione lyase activity
ALPR1_RS19030	COG4628	conserved protein (DUF2132)
ALPR1_RS19050	COG1131	(ABC) transporter
ALPR1_RS19060	COG1028	Short-chain dehydrogenase reductase Sdr
ALPR1_RS19065	COG1473	amidohydrolase
ALPR1_RS19080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ALPR1_RS19095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALPR1_RS19100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALPR1_RS19105	COG0772	Belongs to the SEDS family
ALPR1_RS19110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALPR1_RS19115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALPR1_RS19120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALPR1_RS19125	COG0768	penicillin binding
ALPR1_RS19135	COG0275	rRNA processing
ALPR1_RS19140	COG2001	Belongs to the MraZ family
ALPR1_RS19155	COG1902	pentaerythritol trinitrate reductase activity
ALPR1_RS19165	COG0492	ferredoxin-NADP+ reductase activity
ALPR1_RS19185	COG1349	DNA-binding transcription factor activity
ALPR1_RS19190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ALPR1_RS19195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ALPR1_RS19200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ALPR1_RS19205	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS19210	COG0823	Involved in the tonB-independent uptake of proteins
ALPR1_RS19210	COG1506	peptidase
ALPR1_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
ALPR1_RS19265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS19275	COG0438	transferase activity, transferring glycosyl groups
ALPR1_RS19280	COG0531	amino acid
ALPR1_RS19285	COG1472	Belongs to the glycosyl hydrolase 3 family
ALPR1_RS19295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ALPR1_RS19315	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALPR1_RS19330	COG0701	Predicted permease
ALPR1_RS19360	COG0295	cytidine deaminase activity
ALPR1_RS19375	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ALPR1_RS19380	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ALPR1_RS19385	COG2807	transmembrane transport
ALPR1_RS19390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALPR1_RS19395	COG0475	glutathione-regulated potassium exporter activity
ALPR1_RS19445	COG2181	nitrate reductase activity
ALPR1_RS19445	COG0247	lactate metabolic process
ALPR1_RS19450	COG2181	nitrate reductase activity
ALPR1_RS19450	COG0247	lactate metabolic process
ALPR1_RS19460	COG2885	chlorophyll binding
ALPR1_RS19465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALPR1_RS19490	COG1960	acyl-CoA dehydrogenase activity
ALPR1_RS19500	COG0657	acetylesterase activity
ALPR1_RS19500	COG2755	lipolytic protein G-D-S-L family
ALPR1_RS19530	COG3119	arylsulfatase activity
ALPR1_RS19540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALPR1_RS19545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALPR1_RS19550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALPR1_RS19555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALPR1_RS19560	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALPR1_RS19565	COG0356	it plays a direct role in the translocation of protons across the membrane
ALPR1_RS19585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ALPR1_RS19590	COG0322	excinuclease ABC activity
ALPR1_RS19610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALPR1_RS19635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALPR1_RS19650	COG1366	Belongs to the anti-sigma-factor antagonist family
ALPR1_RS19660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALPR1_RS19665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALPR1_RS19675	COG1132	(ABC) transporter
ALPR1_RS19685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALPR1_RS19700	COG1862	Preprotein translocase
ALPR1_RS19710	COG0237	dephospho-CoA kinase activity
ALPR1_RS19715	COG3781	membrane
ALPR1_RS19735	COG5492	domain, Protein
ALPR1_RS19740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALPR1_RS19760	COG0450	alkyl hydroperoxide reductase
ALPR1_RS19765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALPR1_RS19790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALPR1_RS19800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALPR1_RS19820	COG3118	belongs to the thioredoxin family
ALPR1_RS19830	COG1187	pseudouridine synthase activity
ALPR1_RS19835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ALPR1_RS19860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALPR1_RS19865	COG1966	Carbon starvation protein
ALPR1_RS19895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALPR1_RS19895	COG5180	pathogenesis
ALPR1_RS19900	COG0195	Participates in both transcription termination and antitermination
ALPR1_RS19900	COG2251	uridine kinase activity
ALPR1_RS19905	COG0779	Required for maturation of 30S ribosomal subunits
ALPR1_RS19910	COG1077	Cell shape determining protein MreB Mrl
ALPR1_RS19925	COG0768	penicillin binding
ALPR1_RS19930	COG0772	Belongs to the SEDS family
ALPR1_RS19960	COG1381	Involved in DNA repair and RecF pathway recombination
ALPR1_RS19965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALPR1_RS19985	COG0564	pseudouridine synthase activity
ALPR1_RS20000	COG0556	nucleotide-excision repair
ALPR1_RS20015	COG2610	gluconate transmembrane transporter activity
ALPR1_RS20025	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ALPR1_RS20035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALPR1_RS20045	COG0596	Alpha beta hydrolase
ALPR1_RS20070	COG3530	Putative quorum-sensing-regulated virulence factor
ALPR1_RS20075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ALPR1_RS20085	COG0363	glucosamine-6-phosphate deaminase activity
ALPR1_RS20090	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALPR1_RS20110	COG3266	domain, Protein
ALPR1_RS20110	COG4932	domain protein
ALPR1_RS20110	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ALPR1_RS20150	COG4585	Histidine kinase
ALPR1_RS20160	COG1045	serine acetyltransferase
ALPR1_RS20170	COG0745	RESPONSE REGULATOR receiver
ALPR1_RS20170	COG3292	Two component regulator propeller
ALPR1_RS20170	COG2205	protein histidine kinase activity
ALPR1_RS20175	COG3852	Histidine kinase
ALPR1_RS20180	COG3852	Histidine kinase
ALPR1_RS20185	COG3852	Histidine kinase
ALPR1_RS20200	COG0739	heme binding
ALPR1_RS20280	COG0463	Glycosyl transferase, family 2
ALPR1_RS20290	COG1215	transferase activity, transferring glycosyl groups
ALPR1_RS20295	COG1216	Glycosyl transferase, family 2
ALPR1_RS20300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALPR1_RS20300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALPR1_RS20315	COG4251	negative regulation of phosphorylation
ALPR1_RS20395	COG3275	phosphorelay sensor kinase activity