locus-tag	class	description
HOO31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOO31_RS00010	COG0592	DNA-directed DNA polymerase activity
HOO31_RS00015	COG0187	DNA topoisomerase II activity
HOO31_RS00020	COG0492	ferredoxin-NADP+ reductase activity
HOO31_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HOO31_RS00045	COG0500	methyltransferase
HOO31_RS00050	COG3842	ATPase activity
HOO31_RS00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO31_RS00115	COG0840	transmembrane signaling receptor activity
HOO31_RS00120	COG0840	transmembrane signaling receptor activity
HOO31_RS00125	COG2081	HI0933 family
HOO31_RS00150	COG1959	2 iron, 2 sulfur cluster binding
HOO31_RS00165	COG0175	sulfate reduction
HOO31_RS00170	COG0175	sulfate reduction
HOO31_RS00175	COG2895	sulfate adenylyltransferase (ATP) activity
HOO31_RS00185	COG2814	Major facilitator Superfamily
HOO31_RS00190	COG0783	Belongs to the Dps family
HOO31_RS00195	COG0546	phosphoglycolate phosphatase activity
HOO31_RS00205	COG1012	belongs to the aldehyde dehydrogenase family
HOO31_RS00210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOO31_RS00225	COG3022	response to hydroperoxide
HOO31_RS00245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOO31_RS00250	COG0233	cytoplasmic translational termination
HOO31_RS00255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HOO31_RS00265	COG0352	thiamine-phosphate diphosphorylase activity
HOO31_RS00270	COG0670	Belongs to the BI1 family
HOO31_RS00300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOO31_RS00320	COG1459	type II secretion system
HOO31_RS00325	COG0598	Magnesium transport protein CorA
HOO31_RS00340	COG1178	ABC-type Fe3 transport system permease component
HOO31_RS00345	COG1840	ABC-type Fe3 transport system, periplasmic component
HOO31_RS00400	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOO31_RS00405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HOO31_RS00410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HOO31_RS00415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HOO31_RS00420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOO31_RS00425	COG1077	Cell shape determining protein MreB Mrl
HOO31_RS00440	COG0445	tRNA wobble uridine modification
HOO31_RS00445	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOO31_RS00450	COG4221	oxidoreductase activity
HOO31_RS00455	COG0659	secondary active sulfate transmembrane transporter activity
HOO31_RS00470	COG1222	aaa ATPase
HOO31_RS00480	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HOO31_RS00485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HOO31_RS00500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HOO31_RS00505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOO31_RS00515	COG1086	Polysaccharide biosynthesis protein
HOO31_RS00520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HOO31_RS00530	COG1083	cytidylyl-transferase
HOO31_RS00540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO31_RS00570	COG1028	Short-chain dehydrogenase reductase Sdr
HOO31_RS00575	COG4221	oxidoreductase activity
HOO31_RS00580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO31_RS00595	COG0318	PFAM AMP-dependent synthetase and ligase
HOO31_RS00595	COG0204	Acyl-transferase
HOO31_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
HOO31_RS00610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HOO31_RS00615	COG2089	acid synthase
HOO31_RS00620	COG3980	spore coat polysaccharide biosynthesis protein
HOO31_RS00650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOO31_RS00665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOO31_RS00675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOO31_RS00680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOO31_RS00685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOO31_RS00710	COG1420	regulation of RNA biosynthetic process
HOO31_RS00715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOO31_RS00720	COG0443	Heat shock 70 kDa protein
HOO31_RS00740	COG2121	Domain of unknown function (DUF374)
HOO31_RS00745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOO31_RS00755	COG0195	Participates in both transcription termination and antitermination
HOO31_RS00760	COG0215	cysteine-tRNA ligase activity
HOO31_RS00765	COG1393	Belongs to the ArsC family
HOO31_RS00770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOO31_RS00775	COG0343	queuine tRNA-ribosyltransferase activity
HOO31_RS00805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOO31_RS00810	COG0557	exoribonuclease II activity
HOO31_RS00820	COG1466	dna polymerase III delta subunit
HOO31_RS00825	COG0360	Binds together with S18 to 16S ribosomal RNA
HOO31_RS00830	COG0629	single-stranded DNA binding
HOO31_RS00835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOO31_RS00845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOO31_RS00860	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HOO31_RS00870	COG0157	Belongs to the NadC ModD family
HOO31_RS00885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HOO31_RS00895	COG0083	homoserine kinase activity
HOO31_RS00905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOO31_RS00910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOO31_RS00915	COG0779	Required for maturation of 30S ribosomal subunits
HOO31_RS00920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO31_RS00920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO31_RS00925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOO31_RS00930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HOO31_RS00935	COG1185	polyribonucleotide nucleotidyltransferase activity
HOO31_RS00935	COG0539	negative regulation of cytoplasmic translation
HOO31_RS00940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOO31_RS00945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HOO31_RS00950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO31_RS00950	COG0072	phenylalanine-tRNA ligase activity
HOO31_RS00955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOO31_RS00960	COG0537	adenosine 5'-monophosphoramidase activity
HOO31_RS00965	COG0825	malonyl-CoA metabolic process
HOO31_RS00970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HOO31_RS00975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOO31_RS00985	COG0602	queuosine metabolic process
HOO31_RS00995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HOO31_RS01015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HOO31_RS01025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HOO31_RS01030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HOO31_RS01035	COG1074	ATP-dependent DNA helicase activity
HOO31_RS01045	COG0356	it plays a direct role in the translocation of protons across the membrane
HOO31_RS01050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HOO31_RS01055	COG0191	fructose-bisphosphate aldolase activity
HOO31_RS01065	COG0745	RESPONSE REGULATOR receiver
HOO31_RS01070	COG0642	Histidine kinase
HOO31_RS01100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOO31_RS01110	COG3287	FIST C domain
HOO31_RS01110	COG2200	EAL domain
HOO31_RS01110	COG2199	diguanylate cyclase activity
HOO31_RS01130	COG3043	anaerobic respiration
HOO31_RS01135	COG0348	domain, Protein
HOO31_RS01140	COG0437	4 iron, 4 sulfur cluster binding
HOO31_RS01145	COG0243	molybdopterin cofactor binding
HOO31_RS01160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOO31_RS01165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOO31_RS01170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOO31_RS01180	COG2404	hydrolase activity, acting on ester bonds
HOO31_RS01190	COG0840	transmembrane signaling receptor activity
HOO31_RS01215	COG2030	dehydratase
HOO31_RS01235	COG1401	restriction endodeoxyribonuclease activity
HOO31_RS01245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HOO31_RS01250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HOO31_RS01255	COG0542	response to heat
HOO31_RS01290	COG0148	phosphopyruvate hydratase activity
HOO31_RS01305	COG2814	Major facilitator Superfamily
HOO31_RS01315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOO31_RS01320	COG0049	tRNA binding
HOO31_RS01325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOO31_RS01330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOO31_RS01335	COG0497	DNA recombination
HOO31_RS01340	COG0840	transmembrane signaling receptor activity
HOO31_RS01345	COG0826	peptidase U32
HOO31_RS01355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOO31_RS01365	COG0752	glycyl-tRNA synthetase alpha subunit
HOO31_RS01370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOO31_RS01380	COG1519	Transferase
HOO31_RS01380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HOO31_RS01385	COG0564	pseudouridine synthase activity
HOO31_RS01390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOO31_RS01395	COG0228	four-way junction DNA binding
HOO31_RS01400	COG1837	Belongs to the UPF0109 family
HOO31_RS01405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOO31_RS01425	COG0745	RESPONSE REGULATOR receiver
HOO31_RS01435	COG4786	Flagellar basal body rod
HOO31_RS01440	COG1815	bacterial-type flagellum-dependent cell motility
HOO31_RS01445	COG1766	The M ring may be actively involved in energy transduction
HOO31_RS01450	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOO31_RS01460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOO31_RS01470	COG1749	Flagellar hook protein flgE
HOO31_RS01475	COG1749	Flagellar hook protein flgE
HOO31_RS01495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOO31_RS01500	COG3951	Flagellar rod assembly protein muramidase FlgJ
HOO31_RS01515	COG1419	protein localization to endoplasmic reticulum
HOO31_RS01520	COG0455	bacterial-type flagellum organization
HOO31_RS01550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOO31_RS01560	COG1157	protein secretion by the type III secretion system
HOO31_RS01570	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOO31_RS01580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HOO31_RS01595	COG1686	Belongs to the peptidase S11 family
HOO31_RS01610	COG0840	transmembrane signaling receptor activity
HOO31_RS01625	COG0745	RESPONSE REGULATOR receiver
HOO31_RS01630	COG1639	'signal transduction protein
HOO31_RS01635	COG0840	transmembrane signaling receptor activity
HOO31_RS01640	COG2199	diguanylate cyclase activity
HOO31_RS01645	COG0840	transmembrane signaling receptor activity
HOO31_RS01650	COG0840	transmembrane signaling receptor activity
HOO31_RS01655	COG0840	transmembrane signaling receptor activity
HOO31_RS01665	COG5001	Diguanylate cyclase
HOO31_RS01665	COG3300	MHYT domain
HOO31_RS01670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOO31_RS01680	COG0336	Belongs to the RNA methyltransferase TrmD family
HOO31_RS01685	COG0335	large ribosomal subunit rRNA binding
HOO31_RS01690	COG0586	Pfam SNARE associated Golgi protein
HOO31_RS01695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HOO31_RS01710	COG0251	oxidation-reduction process
HOO31_RS01715	COG3610	response to peptide
HOO31_RS01720	COG2966	Psort location CytoplasmicMembrane, score
HOO31_RS01735	COG0811	peptide transport
HOO31_RS01750	COG1971	Probably functions as a manganese efflux pump
HOO31_RS01775	COG0628	permease
HOO31_RS01785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HOO31_RS01790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOO31_RS01805	COG3041	Addiction module toxin RelE StbE family
HOO31_RS01820	COG4773	Receptor
HOO31_RS01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOO31_RS01830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOO31_RS01840	COG0142	geranyltranstransferase activity
HOO31_RS01845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HOO31_RS01850	COG0442	prolyl-tRNA aminoacylation
HOO31_RS01855	COG0668	transmembrane transport
HOO31_RS01860	COG0617	tRNA 3'-terminal CCA addition
HOO31_RS01865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HOO31_RS01870	COG1862	Preprotein translocase
HOO31_RS01875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO31_RS01880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO31_RS01895	COG1360	Flagellar Motor Protein
HOO31_RS01900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HOO31_RS01910	COG0495	leucyl-tRNA aminoacylation
HOO31_RS01920	COG0285	dihydrofolate synthase activity
HOO31_RS01940	COG0582	viral genome integration into host DNA
HOO31_RS01995	COG0653	protein targeting
HOO31_RS02025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOO31_RS02035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO31_RS02090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HOO31_RS02095	COG0444	Belongs to the ABC transporter superfamily
HOO31_RS02100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOO31_RS02105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOO31_RS02135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOO31_RS02140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HOO31_RS02155	COG0250	Participates in transcription elongation, termination and antitermination
HOO31_RS02160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOO31_RS02165	COG0081	regulation of translation
HOO31_RS02170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOO31_RS02175	COG0222	ribosome binding
HOO31_RS02180	COG0085	RNA polymerase activity
HOO31_RS02185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOO31_RS02205	COG0386	Belongs to the glutathione peroxidase family
HOO31_RS02210	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HOO31_RS02215	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HOO31_RS02235	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HOO31_RS02250	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HOO31_RS02255	COG0298	carbon dioxide binding
HOO31_RS02260	COG0409	Hydrogenase expression formation protein
HOO31_RS02265	COG4804	nuclease activity
HOO31_RS02275	COG0309	Hydrogenase expression formation protein (HypE)
HOO31_RS02290	COG0310	cobalt ion transport
HOO31_RS02315	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOO31_RS02325	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HOO31_RS02335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOO31_RS02345	COG1295	ribonuclease BN
HOO31_RS02350	COG0277	FAD linked oxidase domain protein
HOO31_RS02360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOO31_RS02365	COG2226	methyltransferase
HOO31_RS02370	COG0196	riboflavin kinase activity
HOO31_RS02415	COG1739	Uncharacterized protein family UPF0029
HOO31_RS02440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HOO31_RS02470	COG0438	transferase activity, transferring glycosyl groups
HOO31_RS02490	COG0438	transferase activity, transferring glycosyl groups
HOO31_RS02510	COG0859	PFAM glycosyl transferase family 9
HOO31_RS02525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HOO31_RS02530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HOO31_RS02530	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HOO31_RS02540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HOO31_RS02550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HOO31_RS02560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOO31_RS02575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOO31_RS02585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HOO31_RS02635	COG1136	(ABC) transporter
HOO31_RS02650	COG2353	YceI-like domain
HOO31_RS02660	COG1408	metallophosphoesterase
HOO31_RS02675	COG1121	(ABC) transporter
HOO31_RS02680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HOO31_RS02685	COG2996	Protein conserved in bacteria
HOO31_RS02690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOO31_RS02710	COG0525	valine-tRNA ligase activity
HOO31_RS02735	COG2814	Major facilitator Superfamily
HOO31_RS02740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOO31_RS02760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOO31_RS02770	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO31_RS02775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HOO31_RS02785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOO31_RS02805	COG0439	Biotin carboxylase
HOO31_RS02815	COG2166	iron-sulfur cluster assembly
HOO31_RS02820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOO31_RS02830	COG0396	ATPase activity
HOO31_RS02835	COG0719	Fe-S assembly protein
HOO31_RS02850	COG3706	GGDEF domain
HOO31_RS02855	COG0165	Argininosuccinate lyase
HOO31_RS02860	COG0556	nucleotide-excision repair
HOO31_RS02870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HOO31_RS02875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HOO31_RS02880	COG0784	Response regulator, receiver
HOO31_RS02880	COG0835	chemotaxis
HOO31_RS02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOO31_RS02900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HOO31_RS02905	COG0585	pseudouridine synthase activity
HOO31_RS02915	COG0840	transmembrane signaling receptor activity
HOO31_RS02920	COG0632	four-way junction helicase activity
HOO31_RS02925	COG1181	Belongs to the D-alanine--D-alanine ligase family
HOO31_RS02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HOO31_RS03035	COG0270	DNA (cytosine-5-)-methyltransferase activity
HOO31_RS03075	COG0582	viral genome integration into host DNA
HOO31_RS03090	COG0284	orotidine-5'-phosphate decarboxylase activity
HOO31_RS03095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOO31_RS03100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HOO31_RS03105	COG0174	glutamine synthetase
HOO31_RS03115	COG0314	molybdopterin synthase activity
HOO31_RS03125	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HOO31_RS03130	COG1968	undecaprenyl-diphosphatase activity
HOO31_RS03140	COG0772	Belongs to the SEDS family
HOO31_RS03145	COG0768	penicillin binding
HOO31_RS03150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOO31_RS03155	COG1858	cytochrome C peroxidase
HOO31_RS03185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOO31_RS03200	COG1116	anion transmembrane transporter activity
HOO31_RS03205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HOO31_RS03220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HOO31_RS03230	COG2204	response regulator
HOO31_RS03250	COG0745	RESPONSE REGULATOR receiver
HOO31_RS03255	COG0642	Histidine kinase
HOO31_RS03260	COG2081	HI0933 family
HOO31_RS03265	COG0840	transmembrane signaling receptor activity
HOO31_RS03275	COG3920	Histidine kinase
HOO31_RS03280	COG5002	protein histidine kinase activity
HOO31_RS03285	COG1692	metallophosphoesterase
HOO31_RS03305	COG1570	exodeoxyribonuclease VII activity
HOO31_RS03310	COG0835	chemotaxis
HOO31_RS03320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HOO31_RS03325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOO31_RS03335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOO31_RS03340	COG0459	protein refolding
HOO31_RS03345	COG1686	Belongs to the peptidase S11 family
HOO31_RS03360	COG0848	biopolymer transport protein
HOO31_RS03365	COG0811	peptide transport
HOO31_RS03385	COG1136	(ABC) transporter
HOO31_RS03385	COG0577	efflux transmembrane transporter activity
HOO31_RS03390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOO31_RS03395	COG0542	response to heat
HOO31_RS03400	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HOO31_RS03410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HOO31_RS03415	COG0706	membrane insertase activity
HOO31_RS03425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOO31_RS03445	COG3706	GGDEF domain
HOO31_RS03455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HOO31_RS03460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HOO31_RS03465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOO31_RS03475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOO31_RS03480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HOO31_RS03495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOO31_RS03500	COG0305	Participates in initiation and elongation during chromosome replication
HOO31_RS03515	COG0673	inositol 2-dehydrogenase activity
HOO31_RS03520	COG4771	TonB-dependent receptor
HOO31_RS03540	COG1966	Carbon starvation protein
HOO31_RS03545	COG0563	adenylate kinase activity
HOO31_RS03550	COG0563	adenylate kinase activity
HOO31_RS03560	COG3706	GGDEF domain
HOO31_RS03565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HOO31_RS03570	COG1979	alcohol dehydrogenase
HOO31_RS03575	COG0840	transmembrane signaling receptor activity
HOO31_RS03580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOO31_RS03585	COG0322	excinuclease ABC activity
HOO31_RS03590	COG0840	transmembrane signaling receptor activity
HOO31_RS03615	COG0745	RESPONSE REGULATOR receiver
HOO31_RS03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO31_RS03650	COG0784	Response regulator, receiver
HOO31_RS03650	COG3437	response regulator, receiver
HOO31_RS03655	COG1338	Plays a role in the flagellum-specific transport system
HOO31_RS03660	COG0768	penicillin binding
HOO31_RS03680	COG2884	Cell division ATP-binding protein ftsE
HOO31_RS03685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HOO31_RS03695	COG0564	pseudouridine synthase activity
HOO31_RS03700	COG0772	Belongs to the SEDS family
HOO31_RS03710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HOO31_RS03715	COG3123	guanosine phosphorylase activity
HOO31_RS03795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HOO31_RS03800	COG0569	domain protein
HOO31_RS03800	COG0475	glutathione-regulated potassium exporter activity
HOO31_RS03805	COG0210	DNA helicase
HOO31_RS03810	COG0709	Synthesizes selenophosphate from selenide and ATP
HOO31_RS03815	COG1305	Transglutaminase-like
HOO31_RS03835	COG2204	response regulator
HOO31_RS03875	COG0437	4 iron, 4 sulfur cluster binding
HOO31_RS03885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HOO31_RS03905	COG0303	'Molybdopterin
HOO31_RS03910	COG2998	abc-type tungstate transport system, permease component
HOO31_RS03915	COG4662	Binding-protein-dependent transport system inner membrane component
HOO31_RS03935	COG2814	Major facilitator Superfamily
HOO31_RS03945	COG2354	Protein conserved in bacteria
HOO31_RS03950	COG0726	polysaccharide deacetylase
HOO31_RS03955	COG2081	HI0933 family
HOO31_RS03960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOO31_RS03985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOO31_RS03990	COG2171	N-acyltransferase activity
HOO31_RS03995	COG1944	ATP diphosphatase activity
HOO31_RS04000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOO31_RS04000	COG2169	Transcriptional regulator
HOO31_RS04005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOO31_RS04020	COG4536	flavin adenine dinucleotide binding
HOO31_RS04050	COG0628	permease
HOO31_RS04055	COG2255	four-way junction helicase activity
HOO31_RS04060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HOO31_RS04065	COG0159	tryptophan synthase activity
HOO31_RS04070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HOO31_RS04080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HOO31_RS04095	COG0137	argininosuccinate synthase activity
HOO31_RS04100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOO31_RS04105	COG0742	ribosomal rna small subunit methyltransferase
HOO31_RS04110	COG1418	mRNA catabolic process
HOO31_RS04125	COG0552	protein localization to endoplasmic reticulum
HOO31_RS04145	COG1733	regulation of RNA biosynthetic process
HOO31_RS04150	COG2249	NAD(P)H dehydrogenase (quinone) activity
HOO31_RS04155	COG1902	pentaerythritol trinitrate reductase activity
HOO31_RS04160	COG0778	Nitroreductase
HOO31_RS04170	COG0488	(ABC) transporter
HOO31_RS04175	COG1607	acyl-coa hydrolase
HOO31_RS04180	COG0840	transmembrane signaling receptor activity
HOO31_RS04190	COG0484	heat shock protein binding
HOO31_RS04195	COG0484	heat shock protein binding
HOO31_RS04215	COG0300	oxidoreductase activity
HOO31_RS04225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOO31_RS04230	COG0802	atpase or kinase
HOO31_RS04235	COG1137	ATPase activity
HOO31_RS04260	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HOO31_RS04270	COG2201	protein-glutamate methylesterase activity
HOO31_RS04285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOO31_RS04330	COG2076	Multidrug Resistance protein
HOO31_RS04335	COG0642	Histidine kinase
HOO31_RS04350	COG3258	Cytochrome c
HOO31_RS04360	COG1049	propionate catabolic process, 2-methylcitrate cycle
HOO31_RS04365	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HOO31_RS04370	COG2363	Small membrane protein
HOO31_RS04375	COG1666	GTP binding
HOO31_RS04420	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HOO31_RS04435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO31_RS04435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO31_RS04445	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HOO31_RS04465	COG0762	integral membrane protein
HOO31_RS04470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOO31_RS04475	COG0612	Peptidase, M16
HOO31_RS04480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HOO31_RS04485	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO31_RS04490	COG0287	Prephenate dehydrogenase
HOO31_RS04505	COG0243	molybdopterin cofactor binding
HOO31_RS04515	COG1921	L-seryl-tRNASec selenium transferase activity
HOO31_RS04525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HOO31_RS04530	COG0135	phosphoribosylanthranilate isomerase activity
HOO31_RS04535	COG2176	DNA-directed DNA polymerase activity
HOO31_RS04545	COG1013	pyruvate-flavodoxin oxidoreductase activity
HOO31_RS04550	COG0674	pyruvate-flavodoxin oxidoreductase activity
HOO31_RS04550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HOO31_RS04560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HOO31_RS04565	COG0727	PFAM Uncharacterised protein family (UPF0153)
HOO31_RS04575	COG0134	indole-3-glycerol-phosphate synthase activity
HOO31_RS04580	COG0583	DNA-binding transcription factor activity
HOO31_RS04585	COG1942	4-Oxalocrotonate Tautomerase
HOO31_RS04590	COG2199	diguanylate cyclase activity
HOO31_RS04600	COG0739	heme binding
HOO31_RS04605	COG1610	YqeY-like protein
HOO31_RS04610	COG0488	(ABC) transporter
HOO31_RS04615	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOO31_RS04635	COG0667	Aldo Keto reductase
HOO31_RS04640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOO31_RS04645	COG0805	protein transport
HOO31_RS04650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOO31_RS04660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HOO31_RS04675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HOO31_RS04680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HOO31_RS04685	COG1663	tetraacyldisaccharide 4'-kinase activity
HOO31_RS04690	COG0861	Integral membrane protein TerC family
HOO31_RS04695	COG0789	Transcriptional regulator
HOO31_RS04700	COG0484	heat shock protein binding
HOO31_RS04705	COG4191	Histidine kinase
HOO31_RS04715	COG2201	protein-glutamate methylesterase activity
HOO31_RS04735	COG0776	regulation of translation
HOO31_RS04740	COG0582	viral genome integration into host DNA
HOO31_RS04845	COG0305	Participates in initiation and elongation during chromosome replication
HOO31_RS05020	COG0275	rRNA processing
HOO31_RS05050	COG0039	L-malate dehydrogenase activity
HOO31_RS05060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOO31_RS05070	COG1193	negative regulation of DNA recombination
HOO31_RS05075	COG1253	flavin adenine dinucleotide binding
HOO31_RS05085	COG1119	ATPase activity
HOO31_RS05095	COG2258	MOSC domain
HOO31_RS05100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HOO31_RS05110	COG3135	benzoate transporter
HOO31_RS05120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HOO31_RS05125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOO31_RS05160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOO31_RS05160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOO31_RS05175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOO31_RS05190	COG0527	aspartate kinase activity
HOO31_RS05195	COG0494	nUDIX hydrolase
HOO31_RS05200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HOO31_RS05205	COG2890	protein-(glutamine-N5) methyltransferase activity
HOO31_RS05210	COG0339	signal peptide processing
HOO31_RS05225	COG0824	Thioesterase
HOO31_RS05230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOO31_RS05235	COG0501	Belongs to the peptidase M48B family
HOO31_RS05245	COG2321	neutral zinc metallopeptidase
HOO31_RS05265	COG0037	tRNA processing
HOO31_RS05300	COG0028	Belongs to the TPP enzyme family
HOO31_RS05305	COG0440	acetolactate synthase activity
HOO31_RS05310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HOO31_RS05315	COG1196	nuclear chromosome segregation
HOO31_RS05315	COG1674	ftsk spoiiie
HOO31_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
HOO31_RS05330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOO31_RS05335	COG1160	GTP binding
HOO31_RS05340	COG0659	secondary active sulfate transmembrane transporter activity
HOO31_RS05360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HOO31_RS05370	COG1185	polyribonucleotide nucleotidyltransferase activity
HOO31_RS05375	COG0745	RESPONSE REGULATOR receiver
HOO31_RS05380	COG0643	Histidine kinase
HOO31_RS05380	COG2198	Histidine kinase
HOO31_RS05385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HOO31_RS05390	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HOO31_RS05395	COG2201	protein-glutamate methylesterase activity
HOO31_RS05400	COG0582	viral genome integration into host DNA
HOO31_RS05405	COG0484	heat shock protein binding
HOO31_RS05425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HOO31_RS05435	COG2203	Gaf domain
HOO31_RS05435	COG3706	GGDEF domain
HOO31_RS05435	COG4251	negative regulation of phosphorylation
HOO31_RS05435	COG5001	Diguanylate cyclase
HOO31_RS05440	COG0500	methyltransferase
HOO31_RS05450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HOO31_RS05450	COG1333	cytochrome c biogenesis protein
HOO31_RS05455	COG2195	Cleaves the N-terminal amino acid of tripeptides
HOO31_RS05470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HOO31_RS05475	COG0653	protein targeting
HOO31_RS05485	COG0521	Mo-molybdopterin cofactor biosynthetic process
HOO31_RS05495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOO31_RS05500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOO31_RS05510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOO31_RS05540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HOO31_RS05545	COG4206	TonB-dependent receptor
HOO31_RS05565	COG0546	phosphoglycolate phosphatase activity
HOO31_RS05575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HOO31_RS05600	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HOO31_RS05610	COG4191	Histidine kinase
HOO31_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO31_RS05620	COG0475	glutathione-regulated potassium exporter activity
HOO31_RS05620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HOO31_RS05675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HOO31_RS05680	COG0519	Catalyzes the synthesis of GMP from XMP
HOO31_RS05680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HOO31_RS05715	COG0596	Alpha beta hydrolase
HOO31_RS05730	COG5001	Diguanylate cyclase
HOO31_RS05730	COG5002	protein histidine kinase activity
HOO31_RS05735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HOO31_RS05740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOO31_RS05745	COG0732	type I restriction modification DNA specificity domain
HOO31_RS05755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HOO31_RS05760	COG3177	Filamentation induced by cAMP protein fic
HOO31_RS05780	COG0415	Belongs to the DNA photolyase family
HOO31_RS05785	COG1090	epimerase
HOO31_RS05795	COG3040	lipid binding
HOO31_RS05800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HOO31_RS05815	COG3046	protein related to deoxyribodipyrimidine photolyase
HOO31_RS05830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HOO31_RS05840	COG2200	EAL domain
HOO31_RS05845	COG3279	Response regulator of the LytR AlgR family
HOO31_RS05850	COG3275	phosphorelay sensor kinase activity
HOO31_RS05875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOO31_RS05875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOO31_RS05880	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOO31_RS05890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOO31_RS05895	COG0735	belongs to the Fur family
HOO31_RS05905	COG0728	peptidoglycan biosynthetic process
HOO31_RS05910	COG1132	(ABC) transporter
HOO31_RS05915	COG0167	dihydroorotate dehydrogenase activity
HOO31_RS05920	COG0612	Peptidase, M16
HOO31_RS05925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOO31_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
HOO31_RS05935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOO31_RS05940	COG0750	zinc metalloprotease
HOO31_RS05945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOO31_RS05955	COG0840	transmembrane signaling receptor activity
HOO31_RS05965	COG0642	Histidine kinase
HOO31_RS05970	COG0745	RESPONSE REGULATOR receiver
HOO31_RS05980	COG1132	(ABC) transporter
HOO31_RS05985	COG0217	transcriptional regulatory protein
HOO31_RS06005	COG1611	Belongs to the LOG family
HOO31_RS06010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO31_RS06030	COG0351	phosphomethylpyrimidine kinase
HOO31_RS06030	COG0352	thiamine-phosphate diphosphorylase activity
HOO31_RS06035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOO31_RS06070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HOO31_RS06075	COG1696	Membrane protein involved in D-alanine export
HOO31_RS06090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOO31_RS06115	COG5002	protein histidine kinase activity
HOO31_RS06120	COG0745	RESPONSE REGULATOR receiver
HOO31_RS06145	COG1114	Component of the transport system for branched-chain amino acids
HOO31_RS06150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HOO31_RS06155	COG0788	formyltetrahydrofolate deformylase activity
HOO31_RS06160	COG1496	oxidoreductase activity
HOO31_RS06165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HOO31_RS06170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOO31_RS06180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO31_RS06195	COG0513	Belongs to the DEAD box helicase family
HOO31_RS06205	COG0754	glutathionylspermidine amidase activity
HOO31_RS06210	COG0840	transmembrane signaling receptor activity
HOO31_RS06220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOO31_RS06225	COG0516	GMP reductase activity
HOO31_RS06225	COG0517	IMP dehydrogenase activity
HOO31_RS06230	COG0154	amidase activity
HOO31_RS06235	COG0203	ribosomal protein L17
HOO31_RS06240	COG0202	RNA polymerase activity
HOO31_RS06245	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOO31_RS06250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOO31_RS06255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOO31_RS06260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HOO31_RS06275	COG0473	3-isopropylmalate dehydrogenase activity
HOO31_RS06280	COG0066	3-isopropylmalate dehydratase activity
HOO31_RS06285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOO31_RS06290	COG4974	Belongs to the 'phage' integrase family
HOO31_RS06345	COG0357	Ribosomal RNA small subunit methyltransferase G
HOO31_RS06350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOO31_RS06355	COG0113	porphobilinogen synthase activity
HOO31_RS06395	COG0166	Belongs to the GPI family
HOO31_RS06410	COG2337	Toxic component of a toxin-antitoxin (TA) module
HOO31_RS06420	COG2161	toxin-antitoxin pair type II binding
HOO31_RS06435	COG1086	Polysaccharide biosynthesis protein
HOO31_RS06450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOO31_RS06455	COG2026	Addiction module toxin, RelE StbE family
HOO31_RS06460	COG2161	toxin-antitoxin pair type II binding
HOO31_RS06490	COG0438	transferase activity, transferring glycosyl groups
HOO31_RS06505	COG0367	asparagine synthase
HOO31_RS06515	COG0438	transferase activity, transferring glycosyl groups
HOO31_RS06525	COG1216	Glycosyl transferase, family 2
HOO31_RS06535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOO31_RS06545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HOO31_RS06580	COG3177	Filamentation induced by cAMP protein fic
HOO31_RS06595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HOO31_RS06605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOO31_RS06615	COG2391	methyltransferase activity
HOO31_RS06620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOO31_RS06625	COG0849	cell division
HOO31_RS06635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HOO31_RS06645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOO31_RS06655	COG0446	pyridine nucleotide-disulphide oxidoreductase
HOO31_RS06660	COG0488	(ABC) transporter
HOO31_RS06665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HOO31_RS06675	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HOO31_RS06680	COG0508	dehydrogenase complex catalyzes the overall conversion of
HOO31_RS06685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOO31_RS06695	COG2217	Heavy metal translocating P-type atpase
HOO31_RS06700	COG0513	Belongs to the DEAD box helicase family
HOO31_RS06715	COG0840	transmembrane signaling receptor activity
HOO31_RS06720	COG0328	RNA-DNA hybrid ribonuclease activity
HOO31_RS06725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOO31_RS06735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOO31_RS06745	COG0456	acetyltransferase
HOO31_RS06750	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HOO31_RS06765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HOO31_RS06770	COG0131	Imidazoleglycerol-phosphate dehydratase
HOO31_RS06775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOO31_RS06785	COG0084	hydrolase, TatD family'
HOO31_RS06795	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HOO31_RS06800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HOO31_RS06805	COG0359	binds to the 23S rRNA
HOO31_RS06815	COG0163	prenyltransferase activity
HOO31_RS06820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOO31_RS06825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOO31_RS06830	COG0124	histidyl-tRNA synthetase
HOO31_RS06835	COG1166	arginine decarboxylase activity
HOO31_RS06840	COG1045	serine acetyltransferase
HOO31_RS06845	COG0730	response to heat
HOO31_RS06875	COG1639	'signal transduction protein
HOO31_RS06880	COG0012	GTP binding
HOO31_RS06895	COG3118	belongs to the thioredoxin family
HOO31_RS06900	COG0450	alkyl hydroperoxide reductase
HOO31_RS06905	COG0840	transmembrane signaling receptor activity
HOO31_RS06920	COG3706	GGDEF domain
HOO31_RS06930	COG2855	membrane
HOO31_RS06935	COG0583	DNA-binding transcription factor activity
HOO31_RS06940	COG0500	methyltransferase
HOO31_RS06945	COG2267	carboxylic ester hydrolase activity
HOO31_RS06960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HOO31_RS06970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOO31_RS06990	COG2986	histidine ammonia-lyase
HOO31_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
HOO31_RS07025	COG1131	(ABC) transporter
HOO31_RS07040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HOO31_RS07060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO31_RS07075	COG1032	radical SAM domain protein
HOO31_RS07085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOO31_RS07095	COG1573	uracil-dna glycosylase
HOO31_RS07100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOO31_RS07105	COG0024	Methionine aminopeptidase
HOO31_RS07110	COG0201	protein transport
HOO31_RS07115	COG0200	Binds to the 23S rRNA
HOO31_RS07120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOO31_RS07125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOO31_RS07130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOO31_RS07135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOO31_RS07140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOO31_RS07145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOO31_RS07150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOO31_RS07155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOO31_RS07160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOO31_RS07165	COG0255	Belongs to the universal ribosomal protein uL29 family
HOO31_RS07170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOO31_RS07175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOO31_RS07180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOO31_RS07185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOO31_RS07190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOO31_RS07195	COG0089	rRNA binding
HOO31_RS07200	COG0088	Forms part of the polypeptide exit tunnel
HOO31_RS07205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOO31_RS07210	COG0051	transcription antitermination factor activity, RNA binding
HOO31_RS07230	COG0708	Exodeoxyribonuclease III
HOO31_RS07235	COG0301	tRNA thio-modification
HOO31_RS07235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOO31_RS07255	COG0606	chelatase, subunit chli
HOO31_RS07260	COG0840	transmembrane signaling receptor activity
HOO31_RS07265	COG0840	transmembrane signaling receptor activity
HOO31_RS07275	COG0242	peptide deformylase activity
HOO31_RS07280	COG0740	serine-type endopeptidase activity
HOO31_RS07285	COG0544	peptidyl-prolyl cis-trans isomerase activity
HOO31_RS07290	COG2326	polyphosphate kinase activity
HOO31_RS07315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HOO31_RS07320	COG1355	regulation of microtubule-based process
HOO31_RS07340	COG3256	nitric oxide reductase
HOO31_RS07350	COG2010	Cytochrome c
HOO31_RS07355	COG2010	Cytochrome c
HOO31_RS07360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HOO31_RS07370	COG0535	radical SAM domain protein
HOO31_RS07380	COG1648	precorrin-2 dehydrogenase activity
HOO31_RS07380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HOO31_RS07390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HOO31_RS07390	COG1648	precorrin-2 dehydrogenase activity
HOO31_RS07395	COG1522	sequence-specific DNA binding
HOO31_RS07410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HOO31_RS07425	COG1278	Cold shock
HOO31_RS07430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HOO31_RS07465	COG2217	Heavy metal translocating P-type atpase
HOO31_RS07470	COG2199	diguanylate cyclase activity
HOO31_RS07470	COG2200	EAL domain
HOO31_RS07470	COG3287	FIST C domain
HOO31_RS07475	COG0194	GDP metabolic process
HOO31_RS07485	COG1136	(ABC) transporter
HOO31_RS07490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOO31_RS07495	COG0052	Belongs to the universal ribosomal protein uS2 family
HOO31_RS07500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOO31_RS07515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOO31_RS07520	COG0579	oxidoreductase
HOO31_RS07525	COG1058	Belongs to the CinA family
HOO31_RS07525	COG1546	Belongs to the CinA family
HOO31_RS07575	COG0745	RESPONSE REGULATOR receiver
HOO31_RS07585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOO31_RS07595	COG2176	DNA-directed DNA polymerase activity
HOO31_RS07625	COG2176	DNA-directed DNA polymerase activity
HOO31_RS07635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOO31_RS07640	COG0280	phosphate acetyltransferase
HOO31_RS07650	COG0616	signal peptide processing
HOO31_RS07655	COG0402	S-adenosylhomocysteine deaminase activity
HOO31_RS07660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HOO31_RS07665	COG0006	proline dipeptidase activity
HOO31_RS07670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOO31_RS07675	COG0482	sulfurtransferase activity
HOO31_RS07680	COG0482	sulfurtransferase activity
HOO31_RS07690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOO31_RS07700	COG0481	GTPase activity
HOO31_RS07705	COG1040	competence protein
HOO31_RS07710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOO31_RS07715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOO31_RS07730	COG2095	MarC family integral membrane protein
HOO31_RS07735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOO31_RS07750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOO31_RS07755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOO31_RS07760	COG2264	protein methyltransferase activity
HOO31_RS07765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOO31_RS07775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOO31_RS07785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOO31_RS07790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOO31_RS07795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HOO31_RS07810	COG0840	transmembrane signaling receptor activity
HOO31_RS07875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HOO31_RS07885	COG0133	tryptophan synthase activity
HOO31_RS07890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOO31_RS07895	COG1793	dna ligase
HOO31_RS07905	COG0626	cystathionine gamma-synthase activity
HOO31_RS07935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HOO31_RS07975	COG0528	UMP kinase activity
HOO31_RS07980	COG1758	RNA polymerase activity
HOO31_RS07985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOO31_RS07990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOO31_RS08000	COG0860	N-Acetylmuramoyl-L-alanine amidase
HOO31_RS08015	COG0193	aminoacyl-tRNA hydrolase activity
HOO31_RS08020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HOO31_RS08025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOO31_RS08030	COG0681	Belongs to the peptidase S26 family
HOO31_RS08035	COG0698	ribose 5-phosphate isomerase
HOO31_RS08075	COG2199	diguanylate cyclase activity
HOO31_RS08075	COG3287	FIST C domain
HOO31_RS08075	COG2200	EAL domain
HOO31_RS08080	COG0259	pyridoxamine-phosphate oxidase activity
HOO31_RS08085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOO31_RS08095	COG0513	Belongs to the DEAD box helicase family
HOO31_RS08125	COG0326	Molecular chaperone. Has ATPase activity
HOO31_RS08135	COG0010	Belongs to the arginase family
HOO31_RS08140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HOO31_RS08145	COG0581	inorganic phosphate transmembrane transporter activity
HOO31_RS08150	COG0573	inorganic phosphate transmembrane transporter activity
HOO31_RS08155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HOO31_RS08165	COG4335	DNA alkylation repair
HOO31_RS08170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOO31_RS08180	COG2264	protein methyltransferase activity
HOO31_RS08205	COG2995	paraquat-inducible protein a
HOO31_RS08210	COG3008	intermembrane lipid transfer
HOO31_RS08215	COG0753	catalase activity
HOO31_RS08230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HOO31_RS08235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOO31_RS08245	COG0519	Catalyzes the synthesis of GMP from XMP
HOO31_RS08250	COG1204	response to ionizing radiation
HOO31_RS08260	COG0668	transmembrane transport
HOO31_RS08265	COG1227	inorganic diphosphatase activity
HOO31_RS08280	COG1027	Aspartate ammonia-lyase
HOO31_RS08285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOO31_RS08290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HOO31_RS08295	COG1047	Peptidyl-prolyl cis-trans
HOO31_RS08310	COG0823	Involved in the tonB-independent uptake of proteins
HOO31_RS08320	COG0848	biopolymer transport protein
HOO31_RS08325	COG0811	peptide transport
HOO31_RS08330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HOO31_RS08335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOO31_RS08340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOO31_RS08345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOO31_RS08350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOO31_RS08355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOO31_RS08365	COG1475	DNA binding
HOO31_RS08370	COG1192	Involved in chromosome partitioning
HOO31_RS08385	COG0840	transmembrane signaling receptor activity
HOO31_RS08390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOO31_RS08395	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOO31_RS08400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOO31_RS08405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HOO31_RS08410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HOO31_RS08415	COG0358	DNA primase activity
HOO31_RS08425	COG0571	ribonuclease III activity
HOO31_RS08430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOO31_RS08440	COG2326	polyphosphate kinase activity
HOO31_RS08455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOO31_RS08480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOO31_RS08490	COG0739	heme binding
HOO31_RS08490	COG0741	lytic transglycosylase activity
HOO31_RS08490	COG1196	nuclear chromosome segregation
HOO31_RS08510	COG2183	response to ionizing radiation
HOO31_RS08515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HOO31_RS08520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HOO31_RS08525	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HOO31_RS08530	COG0649	NAD binding
HOO31_RS08530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HOO31_RS08535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HOO31_RS08545	COG0372	Belongs to the citrate synthase family
HOO31_RS08555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HOO31_RS08560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HOO31_RS08565	COG0839	Belongs to the complex I subunit 6 family
HOO31_RS08570	COG0713	ATP synthesis coupled electron transport
HOO31_RS08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HOO31_RS08585	COG1007	ATP synthesis coupled electron transport
HOO31_RS08595	COG1053	succinate dehydrogenase
HOO31_RS08600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HOO31_RS08620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO31_RS08625	COG0416	fatty acid biosynthetic process
HOO31_RS08630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HOO31_RS08640	COG0105	UTP biosynthetic process
HOO31_RS08650	COG0450	alkyl hydroperoxide reductase
HOO31_RS08655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOO31_RS08660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HOO31_RS08665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HOO31_RS08670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOO31_RS08680	COG0181	hydroxymethylbilane synthase activity
HOO31_RS08685	COG1335	isochorismatase
HOO31_RS08725	COG3278	Belongs to the heme-copper respiratory oxidase family
HOO31_RS08730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HOO31_RS08735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOO31_RS08740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOO31_RS08755	COG1242	4 iron, 4 sulfur cluster binding
HOO31_RS08760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOO31_RS08765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HOO31_RS08770	COG0492	ferredoxin-NADP+ reductase activity
HOO31_RS08775	COG3118	belongs to the thioredoxin family
HOO31_RS08780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOO31_RS08805	COG0642	Histidine kinase
HOO31_RS08810	COG0745	RESPONSE REGULATOR receiver
HOO31_RS08820	COG0129	dihydroxy-acid dehydratase activity
HOO31_RS08850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOO31_RS08870	COG0585	pseudouridine synthase activity
HOO31_RS08885	COG0793	Belongs to the peptidase S41A family
HOO31_RS08890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HOO31_RS08895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOO31_RS08900	COG0047	phosphoribosylformylglycinamidine synthase activity
HOO31_RS08910	COG0204	Acyl-transferase
HOO31_RS08915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOO31_RS08920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOO31_RS08925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOO31_RS08930	COG0018	arginyl-trna synthetase
HOO31_RS08940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOO31_RS08945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HOO31_RS08950	COG0126	phosphoglycerate kinase activity
HOO31_RS08955	COG0149	triose-phosphate isomerase activity
HOO31_RS08960	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HOO31_RS08965	COG0019	diaminopimelate decarboxylase activity
HOO31_RS08970	COG0077	Prephenate dehydratase
HOO31_RS08970	COG1605	Chorismate mutase
HOO31_RS08975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOO31_RS08980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOO31_RS08995	COG0424	maF-like protein
HOO31_RS09005	COG0791	NLP P60 protein
HOO31_RS09030	COG3118	belongs to the thioredoxin family
HOO31_RS09035	COG0189	ligase activity
HOO31_RS09050	COG2199	diguanylate cyclase activity
HOO31_RS09050	COG2200	EAL domain
HOO31_RS09050	COG3287	FIST C domain
HOO31_RS09055	COG0688	phosphatidylethanolamine metabolic process
HOO31_RS09065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HOO31_RS09075	COG0288	reversible hydration of carbon dioxide
HOO31_RS09080	COG0156	8-amino-7-oxononanoate synthase activity
HOO31_RS09085	COG0792	nuclease activity
HOO31_RS09105	COG5002	protein histidine kinase activity
HOO31_RS09110	COG0745	RESPONSE REGULATOR receiver
HOO31_RS09160	COG1987	bacterial-type flagellum assembly
HOO31_RS09170	COG1706	bacterial-type flagellum-dependent cell motility
HOO31_RS09190	COG0004	ammonium transporteR
HOO31_RS09195	COG0666	response to abiotic stimulus
HOO31_RS09200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HOO31_RS09225	COG1742	UPF0060 membrane protein
HOO31_RS09240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOO31_RS09250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOO31_RS09265	COG0840	transmembrane signaling receptor activity
HOO31_RS09315	COG2022	thiamine diphosphate biosynthetic process
HOO31_RS09320	COG1324	tolerance protein
HOO31_RS09325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HOO31_RS09325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOO31_RS09335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOO31_RS09350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HOO31_RS09355	COG0575	Belongs to the CDS family
HOO31_RS09380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOO31_RS09385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOO31_RS09390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HOO31_RS09395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOO31_RS09405	COG0446	pyridine nucleotide-disulphide oxidoreductase
HOO31_RS09410	COG0746	molybdenum cofactor guanylyltransferase activity
HOO31_RS09415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOO31_RS09420	COG1393	Belongs to the ArsC family
HOO31_RS09430	COG1696	Membrane protein involved in D-alanine export
HOO31_RS09440	COG2828	Protein conserved in bacteria
HOO31_RS09445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOO31_RS09455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HOO31_RS09465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOO31_RS09470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HOO31_RS09475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOO31_RS09480	COG0560	Phosphoserine phosphatase
HOO31_RS09490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOO31_RS09495	COG0786	glutamate:sodium symporter activity
HOO31_RS09515	COG0736	holo-[acyl-carrier-protein] synthase activity
HOO31_RS09520	COG0601	transmembrane transport
HOO31_RS09525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HOO31_RS09535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOO31_RS09570	COG2824	Alkylphosphonate utilization operon protein PhnA
HOO31_RS09575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HOO31_RS09585	COG0573	inorganic phosphate transmembrane transporter activity
HOO31_RS09590	COG0581	inorganic phosphate transmembrane transporter activity
HOO31_RS09595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HOO31_RS09600	COG0704	Plays a role in the regulation of phosphate uptake
HOO31_RS09610	COG0745	RESPONSE REGULATOR receiver
HOO31_RS09615	COG5002	protein histidine kinase activity
HOO31_RS09620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOO31_RS09625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HOO31_RS09630	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOO31_RS09690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HOO31_RS09695	COG1854	S-ribosylhomocysteine lyase activity
HOO31_RS09705	COG1686	Belongs to the peptidase S11 family
HOO31_RS09715	COG5002	protein histidine kinase activity
HOO31_RS09720	COG1410	methionine synthase
HOO31_RS09720	COG0646	methionine synthase
HOO31_RS09745	COG0140	phosphoribosyl-ATP diphosphatase activity
HOO31_RS09745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOO31_RS09760	COG0456	acetyltransferase
HOO31_RS09765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOO31_RS09770	COG1917	Cupin 2, conserved barrel domain protein
HOO31_RS09785	COG0489	protein tyrosine kinase activity
HOO31_RS09790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HOO31_RS09800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HOO31_RS09800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HOO31_RS09810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HOO31_RS09815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOO31_RS09820	COG0268	Binds directly to 16S ribosomal RNA
HOO31_RS09825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOO31_RS09830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOO31_RS09835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HOO31_RS09845	COG0540	Belongs to the ATCase OTCase family
HOO31_RS09850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOO31_RS09855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HOO31_RS09860	COG0505	Belongs to the CarA family
HOO31_RS09870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOO31_RS09875	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOO31_RS09880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HOO31_RS09910	COG4895	conserved protein (DUF2196)
HOO31_RS09915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HOO31_RS09920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HOO31_RS09925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HOO31_RS09930	COG0237	dephospho-CoA kinase activity
HOO31_RS09940	COG0348	domain, Protein
HOO31_RS09945	COG0504	CTP synthase activity
HOO31_RS09950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HOO31_RS09950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HOO31_RS09965	COG0693	protein deglycase activity
HOO31_RS09970	COG0587	DNA-directed DNA polymerase activity
HOO31_RS09975	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HOO31_RS09990	COG0315	cyclic pyranopterin monophosphate synthase activity
HOO31_RS09995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HOO31_RS10000	COG0428	transporter
HOO31_RS10050	COG0109	protoheme IX farnesyltransferase activity
HOO31_RS10060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOO31_RS10065	COG0254	rRNA binding
HOO31_RS10070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOO31_RS10075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOO31_RS10085	COG0436	Aminotransferase
HOO31_RS10090	COG0460	homoserine dehydrogenase
HOO31_RS10095	COG0564	pseudouridine synthase activity
HOO31_RS10100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOO31_RS10105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOO31_RS10110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOO31_RS10115	COG2885	chlorophyll binding
HOO31_RS10115	COG3047	cAMP biosynthetic process
HOO31_RS10125	COG4206	TonB-dependent receptor
HOO31_RS10135	COG4191	Histidine kinase
HOO31_RS10160	COG0604	alcohol dehydrogenase
HOO31_RS10165	COG1733	regulation of RNA biosynthetic process
HOO31_RS10170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HOO31_RS10175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOO31_RS10185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO31_RS10185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO31_RS10190	COG0511	ligase activity, forming carbon-carbon bonds
HOO31_RS10195	COG0439	Biotin carboxylase
HOO31_RS10205	COG1278	Cold shock
HOO31_RS10220	COG0306	phosphate transporter
HOO31_RS10230	COG0367	asparagine synthase
HOO31_RS10240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HOO31_RS10245	COG1981	membrane
HOO31_RS10250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HOO31_RS10250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HOO31_RS10255	COG1187	pseudouridine synthase activity
HOO31_RS10260	COG0517	IMP dehydrogenase activity
HOO31_RS10260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HOO31_RS10265	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOO31_RS10270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HOO31_RS10275	COG0107	imidazoleglycerol-phosphate synthase activity
HOO31_RS10290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HOO31_RS10295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOO31_RS10300	COG0724	RNA recognition motif
HOO31_RS10305	COG0745	RESPONSE REGULATOR receiver
HOO31_RS10310	COG0642	Histidine kinase
HOO31_RS10330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO31_RS10335	COG2353	YceI-like domain
HOO31_RS10340	COG0133	tryptophan synthase activity
HOO31_RS10355	COG1408	metallophosphoesterase
HOO31_RS10370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HOO31_RS10375	COG4208	sulfate ABC transporter
HOO31_RS10380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HOO31_RS10390	COG2199	diguanylate cyclase activity
HOO31_RS10390	COG3287	FIST C domain
HOO31_RS10390	COG2200	EAL domain
HOO31_RS10405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HOO31_RS10410	COG1959	2 iron, 2 sulfur cluster binding
HOO31_RS10415	COG1217	gtp-binding protein TYPA
HOO31_RS10420	COG2391	methyltransferase activity
HOO31_RS10425	COG0425	Belongs to the sulfur carrier protein TusA family
HOO31_RS10440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HOO31_RS10470	COG0745	RESPONSE REGULATOR receiver
HOO31_RS10475	COG0642	Histidine kinase
HOO31_RS10480	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HOO31_RS10485	COG2860	membrane
HOO31_RS10500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group