locus-tag	class	description
ALANTH_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALANTH_RS00010	COG0592	DNA-directed DNA polymerase activity
ALANTH_RS00015	COG0187	DNA topoisomerase II activity
ALANTH_RS00020	COG2072	flavoprotein involved in K transport
ALANTH_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALANTH_RS00050	COG0500	methyltransferase
ALANTH_RS00055	COG1120	ATPase activity
ALANTH_RS00060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALANTH_RS00070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALANTH_RS00080	COG3842	ATPase activity
ALANTH_RS00110	COG0583	DNA-binding transcription factor activity
ALANTH_RS00125	COG0564	pseudouridine synthase activity
ALANTH_RS00130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ALANTH_RS00135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALANTH_RS00140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALANTH_RS00145	COG3047	cAMP biosynthetic process
ALANTH_RS00145	COG2885	chlorophyll binding
ALANTH_RS00155	COG0604	alcohol dehydrogenase
ALANTH_RS00160	COG1733	regulation of RNA biosynthetic process
ALANTH_RS00165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALANTH_RS00170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALANTH_RS00185	COG1620	l-lactate permease
ALANTH_RS00190	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS00195	COG3852	Histidine kinase
ALANTH_RS00200	COG1556	Lactate utilization protein
ALANTH_RS00205	COG1139	Iron-sulfur cluster binding protein
ALANTH_RS00210	COG0247	lactate metabolic process
ALANTH_RS00215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALANTH_RS00215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALANTH_RS00220	COG0511	ligase activity, forming carbon-carbon bonds
ALANTH_RS00225	COG0439	Biotin carboxylase
ALANTH_RS00230	COG0513	Belongs to the DEAD box helicase family
ALANTH_RS00235	COG0306	phosphate transporter
ALANTH_RS00245	COG0367	asparagine synthase
ALANTH_RS00255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALANTH_RS00260	COG1981	membrane
ALANTH_RS00265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ALANTH_RS00265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALANTH_RS00270	COG1187	pseudouridine synthase activity
ALANTH_RS00275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ALANTH_RS00275	COG0517	IMP dehydrogenase activity
ALANTH_RS00280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ALANTH_RS00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALANTH_RS00290	COG0107	imidazoleglycerol-phosphate synthase activity
ALANTH_RS00305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALANTH_RS00310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALANTH_RS00315	COG0724	RNA recognition motif
ALANTH_RS00320	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS00325	COG0642	Histidine kinase
ALANTH_RS00365	COG0789	Transcriptional regulator
ALANTH_RS00370	COG1335	isochorismatase
ALANTH_RS00375	COG0460	homoserine dehydrogenase
ALANTH_RS00380	COG0436	Aminotransferase
ALANTH_RS00395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALANTH_RS00400	COG0254	rRNA binding
ALANTH_RS00405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALANTH_RS00415	COG0109	protoheme IX farnesyltransferase activity
ALANTH_RS00425	COG0582	viral genome integration into host DNA
ALANTH_RS00495	COG0270	DNA (cytosine-5-)-methyltransferase activity
ALANTH_RS00530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALANTH_RS00535	COG0315	cyclic pyranopterin monophosphate synthase activity
ALANTH_RS00550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALANTH_RS00555	COG0587	DNA-directed DNA polymerase activity
ALANTH_RS00575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ALANTH_RS00575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ALANTH_RS00580	COG0504	CTP synthase activity
ALANTH_RS00585	COG0348	domain, Protein
ALANTH_RS00595	COG0237	dephospho-CoA kinase activity
ALANTH_RS00600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALANTH_RS00605	COG3852	Histidine kinase
ALANTH_RS00610	COG0784	Response regulator, receiver
ALANTH_RS00610	COG2205	protein histidine kinase activity
ALANTH_RS00615	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALANTH_RS00625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALANTH_RS00640	COG2353	YceI-like domain
ALANTH_RS00650	COG2353	YceI-like domain
ALANTH_RS00660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ALANTH_RS00665	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ALANTH_RS00670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALANTH_RS00680	COG0505	Belongs to the CarA family
ALANTH_RS00690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALANTH_RS00700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALANTH_RS00700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALANTH_RS00710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALANTH_RS00715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALANTH_RS00720	COG0489	protein tyrosine kinase activity
ALANTH_RS00730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALANTH_RS00730	COG0140	phosphoribosyl-ATP diphosphatase activity
ALANTH_RS00755	COG1410	methionine synthase
ALANTH_RS00755	COG0646	methionine synthase
ALANTH_RS00765	COG1686	Belongs to the peptidase S11 family
ALANTH_RS00780	COG1854	S-ribosylhomocysteine lyase activity
ALANTH_RS00785	COG1846	Transcriptional regulator
ALANTH_RS00795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALANTH_RS00830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ALANTH_RS00835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALANTH_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALANTH_RS00845	COG5002	protein histidine kinase activity
ALANTH_RS00860	COG0704	Plays a role in the regulation of phosphate uptake
ALANTH_RS00865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALANTH_RS00870	COG0581	inorganic phosphate transmembrane transporter activity
ALANTH_RS00875	COG0573	inorganic phosphate transmembrane transporter activity
ALANTH_RS00880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ALANTH_RS00885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ALANTH_RS00910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALANTH_RS00915	COG0268	Binds directly to 16S ribosomal RNA
ALANTH_RS00920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALANTH_RS00925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALANTH_RS00930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALANTH_RS00935	COG0746	molybdenum cofactor guanylyltransferase activity
ALANTH_RS00940	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALANTH_RS00950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALANTH_RS00955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALANTH_RS00960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALANTH_RS00990	COG0575	Belongs to the CDS family
ALANTH_RS00995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ALANTH_RS01010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALANTH_RS01020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALANTH_RS01020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALANTH_RS01025	COG1324	tolerance protein
ALANTH_RS01030	COG2022	thiamine diphosphate biosynthetic process
ALANTH_RS01065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALANTH_RS01080	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALANTH_RS01085	COG0840	transmembrane signaling receptor activity
ALANTH_RS01095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALANTH_RS01105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ALANTH_RS01110	COG1301	dicarboxylic acid transport
ALANTH_RS01120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALANTH_RS01125	COG4589	Belongs to the CDS family
ALANTH_RS01160	COG0004	ammonium transporteR
ALANTH_RS01165	COG0347	Belongs to the P(II) protein family
ALANTH_RS01170	COG0418	dihydroorotase activity
ALANTH_RS01180	COG1706	bacterial-type flagellum-dependent cell motility
ALANTH_RS01205	COG1580	Controls the rotational direction of flagella during chemotaxis
ALANTH_RS01225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ALANTH_RS01245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALANTH_RS01255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALANTH_RS01260	COG0601	transmembrane transport
ALANTH_RS01265	COG0736	holo-[acyl-carrier-protein] synthase activity
ALANTH_RS01280	COG0786	glutamate:sodium symporter activity
ALANTH_RS01285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALANTH_RS01295	COG0560	Phosphoserine phosphatase
ALANTH_RS01300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALANTH_RS01305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ALANTH_RS01310	COG1393	Belongs to the ArsC family
ALANTH_RS01315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALANTH_RS01320	COG0343	queuine tRNA-ribosyltransferase activity
ALANTH_RS01390	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ALANTH_RS01420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALANTH_RS01425	COG0210	DNA helicase
ALANTH_RS01445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALANTH_RS01450	COG0557	exoribonuclease II activity
ALANTH_RS01455	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ALANTH_RS01460	COG1466	dna polymerase III delta subunit
ALANTH_RS01465	COG0360	Binds together with S18 to 16S ribosomal RNA
ALANTH_RS01470	COG0629	single-stranded DNA binding
ALANTH_RS01475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALANTH_RS01485	COG0215	cysteine-tRNA ligase activity
ALANTH_RS01490	COG0195	Participates in both transcription termination and antitermination
ALANTH_RS01500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALANTH_RS01505	COG2121	Domain of unknown function (DUF374)
ALANTH_RS01515	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ALANTH_RS01525	COG0288	reversible hydration of carbon dioxide
ALANTH_RS01530	COG0156	8-amino-7-oxononanoate synthase activity
ALANTH_RS01535	COG0792	nuclease activity
ALANTH_RS01550	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS01575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALANTH_RS01585	COG0540	Belongs to the ATCase OTCase family
ALANTH_RS01590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALANTH_RS01605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALANTH_RS01610	COG2824	Alkylphosphonate utilization operon protein PhnA
ALANTH_RS01640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALANTH_RS01655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ALANTH_RS01665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALANTH_RS01670	COG2828	Protein conserved in bacteria
ALANTH_RS01675	COG1335	isochorismatase
ALANTH_RS01685	COG0181	hydroxymethylbilane synthase activity
ALANTH_RS01695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALANTH_RS01700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ALANTH_RS01710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALANTH_RS01715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALANTH_RS01720	COG0450	alkyl hydroperoxide reductase
ALANTH_RS01730	COG0105	UTP biosynthetic process
ALANTH_RS01740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALANTH_RS01745	COG0416	fatty acid biosynthetic process
ALANTH_RS01750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALANTH_RS01770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALANTH_RS01775	COG1053	succinate dehydrogenase
ALANTH_RS01785	COG1007	ATP synthesis coupled electron transport
ALANTH_RS01795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALANTH_RS01800	COG0713	ATP synthesis coupled electron transport
ALANTH_RS01810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALANTH_RS01815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ALANTH_RS01820	COG1034	ATP synthesis coupled electron transport
ALANTH_RS01825	COG0372	Belongs to the citrate synthase family
ALANTH_RS01835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ALANTH_RS01840	COG0649	NAD binding
ALANTH_RS01840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALANTH_RS01845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALANTH_RS01850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALANTH_RS01855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ALANTH_RS01860	COG3610	response to peptide
ALANTH_RS01865	COG2966	Psort location CytoplasmicMembrane, score
ALANTH_RS01880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALANTH_RS01895	COG3204	pilus organization
ALANTH_RS01910	COG4774	siderophore transport
ALANTH_RS01920	COG2226	methyltransferase
ALANTH_RS01930	COG4771	TonB-dependent receptor
ALANTH_RS01940	COG1971	Probably functions as a manganese efflux pump
ALANTH_RS01955	COG1132	(ABC) transporter
ALANTH_RS01960	COG1132	(ABC) transporter
ALANTH_RS01960	COG2375	cellular response to nickel ion
ALANTH_RS01980	COG2207	Transcriptional regulator
ALANTH_RS01980	COG1609	Transcriptional regulator
ALANTH_RS02000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALANTH_RS02010	COG2199	diguanylate cyclase activity
ALANTH_RS02010	COG2200	EAL domain
ALANTH_RS02010	COG3287	FIST C domain
ALANTH_RS02015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALANTH_RS02015	COG1333	cytochrome c biogenesis protein
ALANTH_RS02020	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ALANTH_RS02025	COG3005	denitrification pathway
ALANTH_RS02030	COG0840	transmembrane signaling receptor activity
ALANTH_RS02050	COG3043	anaerobic respiration
ALANTH_RS02055	COG0348	domain, Protein
ALANTH_RS02060	COG0437	4 iron, 4 sulfur cluster binding
ALANTH_RS02065	COG0243	molybdopterin cofactor binding
ALANTH_RS02090	COG2204	response regulator
ALANTH_RS02105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALANTH_RS02110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALANTH_RS02115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALANTH_RS02125	COG2404	hydrolase activity, acting on ester bonds
ALANTH_RS02130	COG1832	CoA-binding protein
ALANTH_RS02135	COG0642	Histidine kinase
ALANTH_RS02140	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS02145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALANTH_RS02150	COG0191	fructose-bisphosphate aldolase activity
ALANTH_RS02160	COG0848	biopolymer transport protein
ALANTH_RS02165	COG0811	peptide transport
ALANTH_RS02170	COG2226	methyltransferase
ALANTH_RS02190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALANTH_RS02195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALANTH_RS02205	COG0142	geranyltranstransferase activity
ALANTH_RS02210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALANTH_RS02215	COG0442	prolyl-tRNA aminoacylation
ALANTH_RS02220	COG0668	transmembrane transport
ALANTH_RS02225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ALANTH_RS02225	COG0617	tRNA 3'-terminal CCA addition
ALANTH_RS02225	COG0517	IMP dehydrogenase activity
ALANTH_RS02230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALANTH_RS02235	COG1862	Preprotein translocase
ALANTH_RS02240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALANTH_RS02245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALANTH_RS02260	COG1360	Flagellar Motor Protein
ALANTH_RS02265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ALANTH_RS02275	COG0495	leucyl-tRNA aminoacylation
ALANTH_RS02285	COG0285	dihydrofolate synthase activity
ALANTH_RS02325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALANTH_RS02340	COG2911	Protein conserved in bacteria
ALANTH_RS02355	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS02360	COG0642	Histidine kinase
ALANTH_RS02365	COG2081	HI0933 family
ALANTH_RS02370	COG0840	transmembrane signaling receptor activity
ALANTH_RS02385	COG4191	Histidine kinase
ALANTH_RS02390	COG1692	metallophosphoesterase
ALANTH_RS02405	COG2226	methyltransferase
ALANTH_RS02410	COG1570	exodeoxyribonuclease VII activity
ALANTH_RS02415	COG0835	chemotaxis
ALANTH_RS02425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ALANTH_RS02430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ALANTH_RS02445	COG0459	protein refolding
ALANTH_RS02460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ALANTH_RS02465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALANTH_RS02470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALANTH_RS02475	COG0352	thiamine-phosphate diphosphorylase activity
ALANTH_RS02480	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALANTH_RS02490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALANTH_RS02495	COG2264	protein methyltransferase activity
ALANTH_RS02500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALANTH_RS02505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALANTH_RS02520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALANTH_RS02535	COG2095	MarC family integral membrane protein
ALANTH_RS02545	COG3706	GGDEF domain
ALANTH_RS02550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALANTH_RS02555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALANTH_RS02575	COG3340	Belongs to the peptidase S51 family
ALANTH_RS02580	COG0481	GTPase activity
ALANTH_RS02585	COG1937	Protein conserved in bacteria
ALANTH_RS02600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALANTH_RS02610	COG0482	sulfurtransferase activity
ALANTH_RS02615	COG0482	sulfurtransferase activity
ALANTH_RS02620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALANTH_RS02625	COG0006	proline dipeptidase activity
ALANTH_RS02630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALANTH_RS02635	COG0402	S-adenosylhomocysteine deaminase activity
ALANTH_RS02640	COG0616	signal peptide processing
ALANTH_RS02650	COG0280	phosphate acetyltransferase
ALANTH_RS02655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALANTH_RS02665	COG2176	DNA-directed DNA polymerase activity
ALANTH_RS02685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALANTH_RS02695	COG2176	DNA-directed DNA polymerase activity
ALANTH_RS02705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALANTH_RS02715	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS02770	COG0579	oxidoreductase
ALANTH_RS02775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALANTH_RS02790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALANTH_RS02795	COG0052	Belongs to the universal ribosomal protein uS2 family
ALANTH_RS02800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALANTH_RS02805	COG1136	(ABC) transporter
ALANTH_RS02815	COG0194	GDP metabolic process
ALANTH_RS02820	COG5001	Diguanylate cyclase
ALANTH_RS02820	COG5002	protein histidine kinase activity
ALANTH_RS02825	COG2217	Heavy metal translocating P-type atpase
ALANTH_RS02840	COG4608	Belongs to the ABC transporter superfamily
ALANTH_RS02845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALANTH_RS02850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALANTH_RS02850	COG1648	precorrin-2 dehydrogenase activity
ALANTH_RS02855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALANTH_RS02855	COG1648	precorrin-2 dehydrogenase activity
ALANTH_RS02860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ALANTH_RS02870	COG1121	(ABC) transporter
ALANTH_RS02875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ALANTH_RS02880	COG2996	Protein conserved in bacteria
ALANTH_RS02885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ALANTH_RS02900	COG0210	DNA helicase
ALANTH_RS02905	COG0569	domain protein
ALANTH_RS02905	COG0475	glutathione-regulated potassium exporter activity
ALANTH_RS02910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALANTH_RS02920	COG2010	Cytochrome c
ALANTH_RS02935	COG3258	Cytochrome c
ALANTH_RS02990	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS03045	COG0525	valine-tRNA ligase activity
ALANTH_RS03055	COG4895	conserved protein (DUF2196)
ALANTH_RS03065	COG2814	Major facilitator Superfamily
ALANTH_RS03070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALANTH_RS03090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ALANTH_RS03095	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALANTH_RS03100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALANTH_RS03110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALANTH_RS03125	COG0840	transmembrane signaling receptor activity
ALANTH_RS03130	COG0840	transmembrane signaling receptor activity
ALANTH_RS03150	COG0439	Biotin carboxylase
ALANTH_RS03160	COG2166	iron-sulfur cluster assembly
ALANTH_RS03165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALANTH_RS03175	COG0396	ATPase activity
ALANTH_RS03180	COG0719	Fe-S assembly protein
ALANTH_RS03185	COG2906	2 iron, 2 sulfur cluster binding
ALANTH_RS03185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ALANTH_RS03185	COG0822	iron-sulfur transferase activity
ALANTH_RS03190	COG2239	Acts as a magnesium transporter
ALANTH_RS03200	COG0165	Argininosuccinate lyase
ALANTH_RS03205	COG0784	Response regulator, receiver
ALANTH_RS03205	COG0835	chemotaxis
ALANTH_RS03210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALANTH_RS03215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALANTH_RS03225	COG0556	nucleotide-excision repair
ALANTH_RS03230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALANTH_RS03240	COG0840	transmembrane signaling receptor activity
ALANTH_RS03250	COG0698	ribose 5-phosphate isomerase
ALANTH_RS03255	COG0681	Belongs to the peptidase S26 family
ALANTH_RS03260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALANTH_RS03265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALANTH_RS03270	COG0193	aminoacyl-tRNA hydrolase activity
ALANTH_RS03285	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALANTH_RS03295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALANTH_RS03300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALANTH_RS03305	COG1758	RNA polymerase activity
ALANTH_RS03310	COG0528	UMP kinase activity
ALANTH_RS03350	COG0735	belongs to the Fur family
ALANTH_RS03355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALANTH_RS03360	COG0735	belongs to the Fur family
ALANTH_RS03370	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ALANTH_RS03380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALANTH_RS03390	COG0626	cystathionine gamma-synthase activity
ALANTH_RS03400	COG1793	dna ligase
ALANTH_RS03405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ALANTH_RS03410	COG0133	tryptophan synthase activity
ALANTH_RS03420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALANTH_RS03430	COG0848	biopolymer transport protein
ALANTH_RS03435	COG0811	peptide transport
ALANTH_RS03450	COG0577	efflux transmembrane transporter activity
ALANTH_RS03450	COG1136	(ABC) transporter
ALANTH_RS03455	COG0577	efflux transmembrane transporter activity
ALANTH_RS03455	COG1136	(ABC) transporter
ALANTH_RS03470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALANTH_RS03475	COG0542	response to heat
ALANTH_RS03480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ALANTH_RS03485	COG0594	ribonuclease P activity
ALANTH_RS03490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALANTH_RS03495	COG0706	membrane insertase activity
ALANTH_RS03505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALANTH_RS03540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALANTH_RS03545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALANTH_RS03550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALANTH_RS03560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALANTH_RS03575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALANTH_RS03580	COG0305	Participates in initiation and elongation during chromosome replication
ALANTH_RS03585	COG2165	general secretion pathway protein
ALANTH_RS03590	COG0114	fumarate hydratase activity
ALANTH_RS03605	COG1918	ferrous iron import across plasma membrane
ALANTH_RS03605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ALANTH_RS03610	COG1918	ferrous iron import across plasma membrane
ALANTH_RS03620	COG1131	(ABC) transporter
ALANTH_RS03645	COG1966	Carbon starvation protein
ALANTH_RS03655	COG1639	'signal transduction protein
ALANTH_RS03670	COG3123	guanosine phosphorylase activity
ALANTH_RS03675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ALANTH_RS03680	COG0585	pseudouridine synthase activity
ALANTH_RS03695	COG0632	four-way junction helicase activity
ALANTH_RS03700	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALANTH_RS03710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALANTH_RS03725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALANTH_RS03730	COG0051	transcription antitermination factor activity, RNA binding
ALANTH_RS03735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALANTH_RS03740	COG0088	Forms part of the polypeptide exit tunnel
ALANTH_RS03745	COG0089	rRNA binding
ALANTH_RS03750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALANTH_RS03755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALANTH_RS03760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALANTH_RS03765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALANTH_RS03770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALANTH_RS03775	COG0255	Belongs to the universal ribosomal protein uL29 family
ALANTH_RS03780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALANTH_RS03785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALANTH_RS03790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALANTH_RS03795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALANTH_RS03800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALANTH_RS03805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALANTH_RS03810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALANTH_RS03815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALANTH_RS03820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALANTH_RS03825	COG0200	Binds to the 23S rRNA
ALANTH_RS03830	COG0201	protein transport
ALANTH_RS03835	COG0024	Methionine aminopeptidase
ALANTH_RS03840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALANTH_RS03845	COG1573	uracil-dna glycosylase
ALANTH_RS03855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALANTH_RS03865	COG0563	adenylate kinase activity
ALANTH_RS03870	COG0563	adenylate kinase activity
ALANTH_RS03880	COG2201	protein-glutamate methylesterase activity
ALANTH_RS03905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ALANTH_RS03910	COG1979	alcohol dehydrogenase
ALANTH_RS03915	COG0840	transmembrane signaling receptor activity
ALANTH_RS03920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALANTH_RS03925	COG0322	excinuclease ABC activity
ALANTH_RS03930	COG0840	transmembrane signaling receptor activity
ALANTH_RS03935	COG0840	transmembrane signaling receptor activity
ALANTH_RS03940	COG0840	transmembrane signaling receptor activity
ALANTH_RS03945	COG0784	Response regulator, receiver
ALANTH_RS03945	COG5002	protein histidine kinase activity
ALANTH_RS03950	COG2203	Gaf domain
ALANTH_RS03950	COG3706	GGDEF domain
ALANTH_RS03950	COG4251	negative regulation of phosphorylation
ALANTH_RS03950	COG5001	Diguanylate cyclase
ALANTH_RS03980	COG0708	Exodeoxyribonuclease III
ALANTH_RS04000	COG0166	Belongs to the GPI family
ALANTH_RS04045	COG0500	methyltransferase
ALANTH_RS04050	COG4771	TonB-dependent receptor
ALANTH_RS04055	COG4771	TonB-dependent receptor
ALANTH_RS04065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALANTH_RS04075	COG1393	Belongs to the ArsC family
ALANTH_RS04085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ALANTH_RS04095	COG0849	cell division
ALANTH_RS04100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ALANTH_RS04105	COG2391	methyltransferase activity
ALANTH_RS04115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALANTH_RS04125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALANTH_RS04130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALANTH_RS04150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALANTH_RS04175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALANTH_RS04190	COG2030	dehydratase
ALANTH_RS04205	COG2089	acid synthase
ALANTH_RS04210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ALANTH_RS04260	COG0482	sulfurtransferase activity
ALANTH_RS04275	COG2755	lipolytic protein G-D-S-L family
ALANTH_RS04275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ALANTH_RS04280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALANTH_RS04295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALANTH_RS04305	COG1086	Polysaccharide biosynthesis protein
ALANTH_RS04320	COG0596	Alpha beta hydrolase
ALANTH_RS04350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALANTH_RS04350	COG0519	Catalyzes the synthesis of GMP from XMP
ALANTH_RS04355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ALANTH_RS04365	COG1451	nucleotide metabolic process
ALANTH_RS04370	COG0436	Aminotransferase
ALANTH_RS04405	COG1696	Membrane protein involved in D-alanine export
ALANTH_RS04410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ALANTH_RS04425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ALANTH_RS04435	COG4774	siderophore transport
ALANTH_RS04455	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ALANTH_RS04480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALANTH_RS04485	COG1611	Belongs to the LOG family
ALANTH_RS04500	COG2853	Lipoprotein
ALANTH_RS04505	COG0217	transcriptional regulatory protein
ALANTH_RS04535	COG1049	propionate catabolic process, 2-methylcitrate cycle
ALANTH_RS04540	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ALANTH_RS04545	COG2363	Small membrane protein
ALANTH_RS04550	COG1666	GTP binding
ALANTH_RS04570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALANTH_RS04575	COG0135	phosphoribosylanthranilate isomerase activity
ALANTH_RS04580	COG2176	DNA-directed DNA polymerase activity
ALANTH_RS04595	COG1013	pyruvate-flavodoxin oxidoreductase activity
ALANTH_RS04600	COG0674	pyruvate-flavodoxin oxidoreductase activity
ALANTH_RS04600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ALANTH_RS04610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ALANTH_RS04615	COG0727	PFAM Uncharacterised protein family (UPF0153)
ALANTH_RS04625	COG0134	indole-3-glycerol-phosphate synthase activity
ALANTH_RS04630	COG0583	DNA-binding transcription factor activity
ALANTH_RS04635	COG1942	4-Oxalocrotonate Tautomerase
ALANTH_RS04655	COG0739	heme binding
ALANTH_RS04665	COG0488	(ABC) transporter
ALANTH_RS04670	COG0861	Integral membrane protein TerC family
ALANTH_RS04675	COG0789	Transcriptional regulator
ALANTH_RS04680	COG0484	heat shock protein binding
ALANTH_RS04695	COG2201	protein-glutamate methylesterase activity
ALANTH_RS04710	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ALANTH_RS04715	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ALANTH_RS04730	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ALANTH_RS04735	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ALANTH_RS04745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ALANTH_RS04750	COG0298	carbon dioxide binding
ALANTH_RS04755	COG0409	Hydrogenase expression formation protein
ALANTH_RS04765	COG1401	restriction endodeoxyribonuclease activity
ALANTH_RS04770	COG2084	Dehydrogenase
ALANTH_RS04780	COG0309	Hydrogenase expression formation protein (HypE)
ALANTH_RS04785	COG0375	protein maturation
ALANTH_RS04815	COG0420	3'-5' exonuclease activity
ALANTH_RS04820	COG0419	ATPase involved in DNA repair
ALANTH_RS04860	COG0776	regulation of translation
ALANTH_RS04870	COG0275	rRNA processing
ALANTH_RS04895	COG0039	L-malate dehydrogenase activity
ALANTH_RS04920	COG0653	protein targeting
ALANTH_RS04925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALANTH_RS04935	COG0840	transmembrane signaling receptor activity
ALANTH_RS04960	COG0484	heat shock protein binding
ALANTH_RS04975	COG1132	(ABC) transporter
ALANTH_RS04985	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS04990	COG0642	Histidine kinase
ALANTH_RS05000	COG0840	transmembrane signaling receptor activity
ALANTH_RS05005	COG0840	transmembrane signaling receptor activity
ALANTH_RS05010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALANTH_RS05015	COG3177	Filamentation induced by cAMP protein fic
ALANTH_RS05115	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ALANTH_RS05155	COG3550	peptidyl-serine autophosphorylation
ALANTH_RS05165	COG0750	zinc metalloprotease
ALANTH_RS05170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALANTH_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
ALANTH_RS05180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALANTH_RS05185	COG0612	Peptidase, M16
ALANTH_RS05190	COG0167	dihydroorotate dehydrogenase activity
ALANTH_RS05195	COG1132	(ABC) transporter
ALANTH_RS05200	COG0728	peptidoglycan biosynthetic process
ALANTH_RS05210	COG0735	belongs to the Fur family
ALANTH_RS05215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALANTH_RS05220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALANTH_RS05230	COG1858	cytochrome C peroxidase
ALANTH_RS05245	COG0552	protein localization to endoplasmic reticulum
ALANTH_RS05260	COG1418	mRNA catabolic process
ALANTH_RS05265	COG0742	ribosomal rna small subunit methyltransferase
ALANTH_RS05270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALANTH_RS05280	COG0583	DNA-binding transcription factor activity
ALANTH_RS05285	COG4771	TonB-dependent receptor
ALANTH_RS05290	COG2207	Transcriptional regulator
ALANTH_RS05290	COG1609	Transcriptional regulator
ALANTH_RS05295	COG0300	oxidoreductase activity
ALANTH_RS05310	COG0583	DNA-binding transcription factor activity
ALANTH_RS05315	COG2855	membrane
ALANTH_RS05350	COG1733	regulation of RNA biosynthetic process
ALANTH_RS05360	COG0778	Nitroreductase
ALANTH_RS05370	COG0488	(ABC) transporter
ALANTH_RS05375	COG1607	acyl-coa hydrolase
ALANTH_RS05380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALANTH_RS05385	COG0754	glutathionylspermidine amidase activity
ALANTH_RS05395	COG0697	spore germination
ALANTH_RS05400	COG1114	Component of the transport system for branched-chain amino acids
ALANTH_RS05405	COG0513	Belongs to the DEAD box helicase family
ALANTH_RS05420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALANTH_RS05440	COG0582	viral genome integration into host DNA
ALANTH_RS05445	COG0776	regulation of translation
ALANTH_RS05450	COG0457	Tetratricopeptide repeat
ALANTH_RS05560	COG0358	DNA primase activity
ALANTH_RS05615	COG3287	FIST C domain
ALANTH_RS05615	COG2200	EAL domain
ALANTH_RS05615	COG2199	diguanylate cyclase activity
ALANTH_RS05620	COG1525	nuclease
ALANTH_RS05895	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ALANTH_RS05895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALANTH_RS05930	COG0420	3'-5' exonuclease activity
ALANTH_RS05945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALANTH_RS05960	COG0280	phosphate acetyltransferase
ALANTH_RS05960	COG0281	malic enzyme
ALANTH_RS05965	COG0788	formyltetrahydrofolate deformylase activity
ALANTH_RS05970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALANTH_RS05995	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS06030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALANTH_RS06040	COG0546	phosphoglycolate phosphatase activity
ALANTH_RS06060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALANTH_RS06070	COG4139	cobalamin transport
ALANTH_RS06075	COG0475	glutathione-regulated potassium exporter activity
ALANTH_RS06095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALANTH_RS06105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALANTH_RS06110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALANTH_RS06120	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALANTH_RS06130	COG0488	(ABC) transporter
ALANTH_RS06135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALANTH_RS06145	COG0454	-acetyltransferase
ALANTH_RS06165	COG4773	Receptor
ALANTH_RS06185	COG1733	regulation of RNA biosynthetic process
ALANTH_RS06190	COG2249	NAD(P)H dehydrogenase (quinone) activity
ALANTH_RS06195	COG0596	Alpha beta hydrolase
ALANTH_RS06205	COG1193	negative regulation of DNA recombination
ALANTH_RS06210	COG1253	flavin adenine dinucleotide binding
ALANTH_RS06220	COG1119	ATPase activity
ALANTH_RS06235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALANTH_RS06240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALANTH_RS06245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALANTH_RS06245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALANTH_RS06260	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS06275	COG0113	porphobilinogen synthase activity
ALANTH_RS06280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALANTH_RS06285	COG0357	Ribosomal RNA small subunit methyltransferase G
ALANTH_RS06310	COG0824	Thioesterase
ALANTH_RS06320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALANTH_RS06325	COG0501	Belongs to the peptidase M48B family
ALANTH_RS06340	COG2321	neutral zinc metallopeptidase
ALANTH_RS06360	COG0037	tRNA processing
ALANTH_RS06395	COG0028	Belongs to the TPP enzyme family
ALANTH_RS06400	COG0440	acetolactate synthase activity
ALANTH_RS06405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALANTH_RS06410	COG1196	nuclear chromosome segregation
ALANTH_RS06410	COG1674	ftsk spoiiie
ALANTH_RS06425	COG1160	GTP binding
ALANTH_RS06430	COG0659	secondary active sulfate transmembrane transporter activity
ALANTH_RS06450	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ALANTH_RS06460	COG1185	polyribonucleotide nucleotidyltransferase activity
ALANTH_RS06465	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS06470	COG0643	Histidine kinase
ALANTH_RS06470	COG2198	Histidine kinase
ALANTH_RS06475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALANTH_RS06480	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALANTH_RS06485	COG2201	protein-glutamate methylesterase activity
ALANTH_RS06490	COG2223	nitrite transmembrane transporter activity
ALANTH_RS06495	COG0582	viral genome integration into host DNA
ALANTH_RS06510	COG0339	signal peptide processing
ALANTH_RS06515	COG2890	protein-(glutamine-N5) methyltransferase activity
ALANTH_RS06520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALANTH_RS06525	COG0494	nUDIX hydrolase
ALANTH_RS06530	COG0527	aspartate kinase activity
ALANTH_RS06545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALANTH_RS06555	COG0287	Prephenate dehydrogenase
ALANTH_RS06560	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALANTH_RS06565	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ALANTH_RS06570	COG0612	Peptidase, M16
ALANTH_RS06575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALANTH_RS06600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALANTH_RS06610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALANTH_RS06610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALANTH_RS06635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ALANTH_RS06660	COG3706	GGDEF domain
ALANTH_RS06660	COG5001	Diguanylate cyclase
ALANTH_RS06660	COG2203	Gaf domain
ALANTH_RS06660	COG4251	negative regulation of phosphorylation
ALANTH_RS06665	COG1663	tetraacyldisaccharide 4'-kinase activity
ALANTH_RS06675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ALANTH_RS06695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALANTH_RS06700	COG0805	protein transport
ALANTH_RS06705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALANTH_RS06735	COG0247	lactate metabolic process
ALANTH_RS06735	COG2181	nitrate reductase activity
ALANTH_RS06740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALANTH_RS06755	COG0840	transmembrane signaling receptor activity
ALANTH_RS06760	COG0667	Aldo Keto reductase
ALANTH_RS06790	COG0484	heat shock protein binding
ALANTH_RS06810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALANTH_RS06815	COG2199	diguanylate cyclase activity
ALANTH_RS06820	COG5001	Diguanylate cyclase
ALANTH_RS06820	COG3300	MHYT domain
ALANTH_RS06825	COG0500	methyltransferase
ALANTH_RS06855	COG0582	viral genome integration into host DNA
ALANTH_RS06860	COG1333	cytochrome c biogenesis protein
ALANTH_RS06860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALANTH_RS06865	COG2195	Cleaves the N-terminal amino acid of tripeptides
ALANTH_RS06870	COG0840	transmembrane signaling receptor activity
ALANTH_RS06875	COG0840	transmembrane signaling receptor activity
ALANTH_RS06880	COG0516	GMP reductase activity
ALANTH_RS06880	COG0517	IMP dehydrogenase activity
ALANTH_RS06885	COG0154	amidase activity
ALANTH_RS06890	COG0203	ribosomal protein L17
ALANTH_RS06895	COG0202	RNA polymerase activity
ALANTH_RS06900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALANTH_RS06905	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALANTH_RS06910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALANTH_RS06915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ALANTH_RS06930	COG0473	3-isopropylmalate dehydrogenase activity
ALANTH_RS06935	COG0066	3-isopropylmalate dehydratase activity
ALANTH_RS06940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALANTH_RS06965	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS06995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALANTH_RS07000	COG1687	branched-chain amino acid
ALANTH_RS07005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ALANTH_RS07015	COG0772	Belongs to the SEDS family
ALANTH_RS07020	COG0564	pseudouridine synthase activity
ALANTH_RS07030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALANTH_RS07035	COG2884	Cell division ATP-binding protein ftsE
ALANTH_RS07055	COG0768	penicillin binding
ALANTH_RS07060	COG1338	Plays a role in the flagellum-specific transport system
ALANTH_RS07065	COG0784	Response regulator, receiver
ALANTH_RS07065	COG3437	response regulator, receiver
ALANTH_RS07075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALANTH_RS07100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALANTH_RS07105	COG0415	Belongs to the DNA photolyase family
ALANTH_RS07110	COG1090	epimerase
ALANTH_RS07115	COG0157	Belongs to the NadC ModD family
ALANTH_RS07125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALANTH_RS07125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ALANTH_RS07130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ALANTH_RS07135	COG1137	ATPase activity
ALANTH_RS07140	COG0802	atpase or kinase
ALANTH_RS07145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALANTH_RS07160	COG0137	argininosuccinate synthase activity
ALANTH_RS07165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ALANTH_RS07170	COG1696	Membrane protein involved in D-alanine export
ALANTH_RS07185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALANTH_RS07220	COG0351	phosphomethylpyrimidine kinase
ALANTH_RS07220	COG0352	thiamine-phosphate diphosphorylase activity
ALANTH_RS07225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALANTH_RS07240	COG0348	domain, Protein
ALANTH_RS07250	COG2207	Transcriptional regulator
ALANTH_RS07250	COG4753	response regulator
ALANTH_RS07255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALANTH_RS07280	COG0716	FMN binding
ALANTH_RS07295	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ALANTH_RS07305	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALANTH_RS07310	COG0159	tryptophan synthase activity
ALANTH_RS07315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALANTH_RS07320	COG2255	four-way junction helicase activity
ALANTH_RS07325	COG0628	permease
ALANTH_RS07345	COG0628	permease
ALANTH_RS07365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALANTH_RS07385	COG4774	siderophore transport
ALANTH_RS07405	COG3135	benzoate transporter
ALANTH_RS07410	COG1944	ATP diphosphatase activity
ALANTH_RS07420	COG2258	MOSC domain
ALANTH_RS07430	COG0488	(ABC) transporter
ALANTH_RS07440	COG2171	N-acyltransferase activity
ALANTH_RS07445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALANTH_RS07470	COG2081	HI0933 family
ALANTH_RS07480	COG2354	Protein conserved in bacteria
ALANTH_RS07495	COG2814	Major facilitator Superfamily
ALANTH_RS07510	COG0301	tRNA thio-modification
ALANTH_RS07510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALANTH_RS07530	COG0456	acetyltransferase
ALANTH_RS07535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALANTH_RS07550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALANTH_RS07555	COG0131	Imidazoleglycerol-phosphate dehydratase
ALANTH_RS07560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALANTH_RS07570	COG0084	hydrolase, TatD family'
ALANTH_RS07580	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALANTH_RS07585	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALANTH_RS07590	COG0359	binds to the 23S rRNA
ALANTH_RS07600	COG0163	prenyltransferase activity
ALANTH_RS07605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALANTH_RS07610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALANTH_RS07615	COG0124	histidyl-tRNA synthetase
ALANTH_RS07620	COG1166	arginine decarboxylase activity
ALANTH_RS07625	COG1045	serine acetyltransferase
ALANTH_RS07630	COG0730	response to heat
ALANTH_RS07635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALANTH_RS07640	COG0840	transmembrane signaling receptor activity
ALANTH_RS07650	COG3287	FIST C domain
ALANTH_RS07650	COG2200	EAL domain
ALANTH_RS07650	COG2199	diguanylate cyclase activity
ALANTH_RS07655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALANTH_RS07665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALANTH_RS07670	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALANTH_RS07675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALANTH_RS07685	COG2076	Multidrug Resistance protein
ALANTH_RS07690	COG0642	Histidine kinase
ALANTH_RS07705	COG3258	Cytochrome c
ALANTH_RS07745	COG1518	maintenance of DNA repeat elements
ALANTH_RS07755	COG2217	Heavy metal translocating P-type atpase
ALANTH_RS07760	COG0640	Transcriptional regulator
ALANTH_RS07775	COG0328	RNA-DNA hybrid ribonuclease activity
ALANTH_RS07780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALANTH_RS07810	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALANTH_RS07825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ALANTH_RS07835	COG0437	4 iron, 4 sulfur cluster binding
ALANTH_RS07870	COG2204	response regulator
ALANTH_RS07880	COG4774	siderophore transport
ALANTH_RS07900	COG1305	Transglutaminase-like
ALANTH_RS07910	COG0437	4 iron, 4 sulfur cluster binding
ALANTH_RS07920	COG0709	Synthesizes selenophosphate from selenide and ATP
ALANTH_RS07930	COG1921	L-seryl-tRNASec selenium transferase activity
ALANTH_RS07975	COG4191	Histidine kinase
ALANTH_RS07990	COG1078	dGTPase activity
ALANTH_RS07995	COG3287	FIST C domain
ALANTH_RS07995	COG2200	EAL domain
ALANTH_RS07995	COG2199	diguanylate cyclase activity
ALANTH_RS08000	COG0259	pyridoxamine-phosphate oxidase activity
ALANTH_RS08015	COG0513	Belongs to the DEAD box helicase family
ALANTH_RS08035	COG0326	Molecular chaperone. Has ATPase activity
ALANTH_RS08040	COG3706	GGDEF domain
ALANTH_RS08040	COG2203	Gaf domain
ALANTH_RS08040	COG5001	Diguanylate cyclase
ALANTH_RS08040	COG4251	negative regulation of phosphorylation
ALANTH_RS08060	COG2169	Transcriptional regulator
ALANTH_RS08060	COG1917	Cupin 2, conserved barrel domain protein
ALANTH_RS08065	COG4771	TonB-dependent receptor
ALANTH_RS08075	COG0753	catalase activity
ALANTH_RS08080	COG3008	intermembrane lipid transfer
ALANTH_RS08085	COG2995	paraquat-inducible protein a
ALANTH_RS08125	COG4335	DNA alkylation repair
ALANTH_RS08140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ALANTH_RS08145	COG0573	inorganic phosphate transmembrane transporter activity
ALANTH_RS08150	COG0581	inorganic phosphate transmembrane transporter activity
ALANTH_RS08155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALANTH_RS08160	COG1538	Outer membrane efflux protein
ALANTH_RS08165	COG1136	(ABC) transporter
ALANTH_RS08165	COG0577	efflux transmembrane transporter activity
ALANTH_RS08170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALANTH_RS08190	COG1278	Cold shock
ALANTH_RS08195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALANTH_RS08215	COG0010	Belongs to the arginase family
ALANTH_RS08240	COG1595	DNA-templated transcription, initiation
ALANTH_RS08245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALANTH_RS08250	COG2207	Transcriptional regulator
ALANTH_RS08255	COG0519	Catalyzes the synthesis of GMP from XMP
ALANTH_RS08260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALANTH_RS08265	COG0668	transmembrane transport
ALANTH_RS08270	COG1227	inorganic diphosphatase activity
ALANTH_RS08285	COG1027	Aspartate ammonia-lyase
ALANTH_RS08290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALANTH_RS08295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ALANTH_RS08300	COG1047	Peptidyl-prolyl cis-trans
ALANTH_RS08315	COG0823	Involved in the tonB-independent uptake of proteins
ALANTH_RS08325	COG0848	biopolymer transport protein
ALANTH_RS08330	COG0811	peptide transport
ALANTH_RS08335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALANTH_RS08340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALANTH_RS08345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALANTH_RS08350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALANTH_RS08355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALANTH_RS08360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALANTH_RS08370	COG1475	DNA binding
ALANTH_RS08375	COG1192	Involved in chromosome partitioning
ALANTH_RS08385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALANTH_RS08415	COG1858	cytochrome C peroxidase
ALANTH_RS08425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALANTH_RS08430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALANTH_RS08435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALANTH_RS08440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ALANTH_RS08445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALANTH_RS08450	COG0358	DNA primase activity
ALANTH_RS08460	COG0571	ribonuclease III activity
ALANTH_RS08465	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALANTH_RS08470	COG2326	polyphosphate kinase activity
ALANTH_RS08485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALANTH_RS08495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALANTH_RS08525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALANTH_RS08535	COG0739	heme binding
ALANTH_RS08535	COG0741	lytic transglycosylase activity
ALANTH_RS08535	COG1196	nuclear chromosome segregation
ALANTH_RS08545	COG0598	Magnesium transport protein CorA
ALANTH_RS08570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALANTH_RS08580	COG0606	chelatase, subunit chli
ALANTH_RS08585	COG0840	transmembrane signaling receptor activity
ALANTH_RS08590	COG0840	transmembrane signaling receptor activity
ALANTH_RS08600	COG0242	peptide deformylase activity
ALANTH_RS08605	COG0740	serine-type endopeptidase activity
ALANTH_RS08610	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALANTH_RS08675	COG0731	radical SAM domain protein
ALANTH_RS08680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALANTH_RS08690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ALANTH_RS08705	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALANTH_RS08715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALANTH_RS08735	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ALANTH_RS08735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALANTH_RS08740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ALANTH_RS08755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALANTH_RS08760	COG0859	PFAM glycosyl transferase family 9
ALANTH_RS08770	COG0859	PFAM glycosyl transferase family 9
ALANTH_RS08775	COG0463	Glycosyl transferase, family 2
ALANTH_RS08785	COG0438	transferase activity, transferring glycosyl groups
ALANTH_RS08800	COG1696	Membrane protein involved in D-alanine export
ALANTH_RS08820	COG1216	Glycosyl transferase, family 2
ALANTH_RS08830	COG1216	Glycosyl transferase, family 2
ALANTH_RS08880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALANTH_RS08905	COG1739	Uncharacterized protein family UPF0029
ALANTH_RS08920	COG0196	riboflavin kinase activity
ALANTH_RS08925	COG2226	methyltransferase
ALANTH_RS08930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALANTH_RS08940	COG0277	FAD linked oxidase domain protein
ALANTH_RS08945	COG1295	ribonuclease BN
ALANTH_RS08955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALANTH_RS08960	COG0697	spore germination
ALANTH_RS08965	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALANTH_RS08975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALANTH_RS08980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALANTH_RS08985	COG0284	orotidine-5'-phosphate decarboxylase activity
ALANTH_RS09035	COG2205	protein histidine kinase activity
ALANTH_RS09035	COG0784	Response regulator, receiver
ALANTH_RS09060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALANTH_RS09065	COG0085	RNA polymerase activity
ALANTH_RS09070	COG0222	ribosome binding
ALANTH_RS09075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALANTH_RS09080	COG0081	regulation of translation
ALANTH_RS09085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALANTH_RS09090	COG0250	Participates in transcription elongation, termination and antitermination
ALANTH_RS09105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALANTH_RS09110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALANTH_RS09135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALANTH_RS09140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALANTH_RS09145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ALANTH_RS09150	COG0444	Belongs to the ABC transporter superfamily
ALANTH_RS09155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ALANTH_RS09160	COG0174	glutamine synthetase
ALANTH_RS09170	COG0314	molybdopterin synthase activity
ALANTH_RS09180	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ALANTH_RS09185	COG1968	undecaprenyl-diphosphatase activity
ALANTH_RS09190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALANTH_RS09195	COG0772	Belongs to the SEDS family
ALANTH_RS09200	COG0768	penicillin binding
ALANTH_RS09205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALANTH_RS09240	COG0542	response to heat
ALANTH_RS09245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALANTH_RS09250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ALANTH_RS09265	COG2030	dehydratase
ALANTH_RS09290	COG1970	mechanosensitive ion channel activity
ALANTH_RS09315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALANTH_RS09325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALANTH_RS09330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALANTH_RS09335	COG1157	protein secretion by the type III secretion system
ALANTH_RS09345	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALANTH_RS09365	COG1677	Flagellar hook-basal body complex protein FliE
ALANTH_RS09375	COG0455	bacterial-type flagellum organization
ALANTH_RS09380	COG1419	protein localization to endoplasmic reticulum
ALANTH_RS09420	COG1749	Flagellar hook protein flgE
ALANTH_RS09425	COG1749	Flagellar hook protein flgE
ALANTH_RS09435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALANTH_RS09445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALANTH_RS09450	COG1766	The M ring may be actively involved in energy transduction
ALANTH_RS09455	COG1815	bacterial-type flagellum-dependent cell motility
ALANTH_RS09460	COG4786	Flagellar basal body rod
ALANTH_RS09470	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS09490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALANTH_RS09495	COG1837	Belongs to the UPF0109 family
ALANTH_RS09500	COG0228	four-way junction DNA binding
ALANTH_RS09505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALANTH_RS09510	COG0564	pseudouridine synthase activity
ALANTH_RS09515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALANTH_RS09515	COG1519	Transferase
ALANTH_RS09525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALANTH_RS09530	COG0752	glycyl-tRNA synthetase alpha subunit
ALANTH_RS09540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALANTH_RS09550	COG0826	peptidase U32
ALANTH_RS09555	COG0840	transmembrane signaling receptor activity
ALANTH_RS09560	COG0497	DNA recombination
ALANTH_RS09565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALANTH_RS09570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALANTH_RS09575	COG0049	tRNA binding
ALANTH_RS09580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALANTH_RS09590	COG2814	Major facilitator Superfamily
ALANTH_RS09595	COG4771	TonB-dependent receptor
ALANTH_RS09610	COG1116	anion transmembrane transporter activity
ALANTH_RS09615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALANTH_RS09620	COG3852	Histidine kinase
ALANTH_RS09625	COG4753	response regulator
ALANTH_RS09625	COG2207	Transcriptional regulator
ALANTH_RS09630	COG4774	siderophore transport
ALANTH_RS09685	COG0512	Glutamine amidotransferase of anthranilate synthase
ALANTH_RS09690	COG1840	ABC-type Fe3 transport system, periplasmic component
ALANTH_RS09705	COG2207	Transcriptional regulator
ALANTH_RS09755	COG2183	response to ionizing radiation
ALANTH_RS09760	COG2814	Major facilitator Superfamily
ALANTH_RS09775	COG0251	oxidation-reduction process
ALANTH_RS09790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALANTH_RS09800	COG0586	Pfam SNARE associated Golgi protein
ALANTH_RS09805	COG0335	large ribosomal subunit rRNA binding
ALANTH_RS09810	COG0336	Belongs to the RNA methyltransferase TrmD family
ALANTH_RS09820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALANTH_RS09830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALANTH_RS09835	COG0356	it plays a direct role in the translocation of protons across the membrane
ALANTH_RS09845	COG4773	Receptor
ALANTH_RS09850	COG0210	DNA helicase
ALANTH_RS09855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALANTH_RS09860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ALANTH_RS09865	COG0723	plastoquinol--plastocyanin reductase activity
ALANTH_RS09870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALANTH_RS09885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALANTH_RS09895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ALANTH_RS09905	COG0602	queuosine metabolic process
ALANTH_RS09915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALANTH_RS09920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALANTH_RS09925	COG0825	malonyl-CoA metabolic process
ALANTH_RS09930	COG0537	adenosine 5'-monophosphoramidase activity
ALANTH_RS09935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALANTH_RS09940	COG0072	phenylalanine-tRNA ligase activity
ALANTH_RS09940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALANTH_RS09945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALANTH_RS09950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALANTH_RS09955	COG1185	polyribonucleotide nucleotidyltransferase activity
ALANTH_RS09955	COG0539	negative regulation of cytoplasmic translation
ALANTH_RS09960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALANTH_RS09965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALANTH_RS09970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALANTH_RS09970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALANTH_RS09975	COG0779	Required for maturation of 30S ribosomal subunits
ALANTH_RS09980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALANTH_RS09985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALANTH_RS09995	COG0083	homoserine kinase activity
ALANTH_RS10005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALANTH_RS10015	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ALANTH_RS10020	COG0157	Belongs to the NadC ModD family
ALANTH_RS10030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALANTH_RS10045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ALANTH_RS10050	COG0671	phosphoesterase, PA-phosphatase related
ALANTH_RS10055	COG2887	Belongs to the helicase family. UvrD subfamily
ALANTH_RS10090	COG3278	Belongs to the heme-copper respiratory oxidase family
ALANTH_RS10095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALANTH_RS10100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALANTH_RS10105	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALANTH_RS10120	COG1242	4 iron, 4 sulfur cluster binding
ALANTH_RS10125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ALANTH_RS10130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALANTH_RS10135	COG0492	ferredoxin-NADP+ reductase activity
ALANTH_RS10140	COG3118	belongs to the thioredoxin family
ALANTH_RS10145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALANTH_RS10170	COG4773	Receptor
ALANTH_RS10180	COG1595	DNA-templated transcription, initiation
ALANTH_RS10185	COG0840	transmembrane signaling receptor activity
ALANTH_RS10190	COG0840	transmembrane signaling receptor activity
ALANTH_RS10205	COG0642	Histidine kinase
ALANTH_RS10210	COG0745	RESPONSE REGULATOR receiver
ALANTH_RS10220	COG0129	dihydroxy-acid dehydratase activity
ALANTH_RS10250	COG0585	pseudouridine synthase activity
ALANTH_RS10265	COG0793	Belongs to the peptidase S41A family
ALANTH_RS10270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALANTH_RS10275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALANTH_RS10280	COG0047	phosphoribosylformylglycinamidine synthase activity
ALANTH_RS10290	COG0204	Acyl-transferase
ALANTH_RS10295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALANTH_RS10300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALANTH_RS10305	COG0018	arginyl-trna synthetase
ALANTH_RS10325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALANTH_RS10340	COG0126	phosphoglycerate kinase activity
ALANTH_RS10345	COG0149	triose-phosphate isomerase activity
ALANTH_RS10350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ALANTH_RS10355	COG0019	diaminopimelate decarboxylase activity
ALANTH_RS10360	COG1605	Chorismate mutase
ALANTH_RS10360	COG0077	Prephenate dehydratase
ALANTH_RS10365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALANTH_RS10370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALANTH_RS10380	COG0424	maF-like protein
ALANTH_RS10390	COG0791	NLP P60 protein
ALANTH_RS10405	COG0471	metal ion transport
ALANTH_RS10425	COG0189	ligase activity
ALANTH_RS10440	COG3287	FIST C domain
ALANTH_RS10440	COG2200	EAL domain
ALANTH_RS10440	COG2199	diguanylate cyclase activity
ALANTH_RS10445	COG0688	phosphatidylethanolamine metabolic process
ALANTH_RS10455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ALANTH_RS10460	COG0443	Heat shock 70 kDa protein
ALANTH_RS10465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALANTH_RS10480	COG2819	hydrolase of the alpha beta superfamily
ALANTH_RS10485	COG0101	tRNA pseudouridine synthase activity
ALANTH_RS10500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALANTH_RS10505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ALANTH_RS10510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALANTH_RS10520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALANTH_RS10525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALANTH_RS10580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ALANTH_RS10590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALANTH_RS10595	COG2226	methyltransferase
ALANTH_RS10620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ALANTH_RS10625	COG0562	UDP-galactopyranose mutase
ALANTH_RS10630	COG1215	transferase activity, transferring glycosyl groups
ALANTH_RS10630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ALANTH_RS10640	COG1028	Short-chain dehydrogenase reductase Sdr
ALANTH_RS10650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALANTH_RS10655	COG2089	acid synthase
ALANTH_RS10660	COG3980	spore coat polysaccharide biosynthesis protein
ALANTH_RS10665	COG1083	cytidylyl-transferase
ALANTH_RS10670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALANTH_RS10675	COG1086	Polysaccharide biosynthesis protein
ALANTH_RS10685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALANTH_RS10690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALANTH_RS10710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALANTH_RS10715	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ALANTH_RS10725	COG1222	aaa ATPase
ALANTH_RS10740	COG0659	secondary active sulfate transmembrane transporter activity
ALANTH_RS10755	COG2814	Major facilitator Superfamily
ALANTH_RS10765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ALANTH_RS10770	COG1252	NADH dehydrogenase
ALANTH_RS10775	COG0733	neurotransmitter:sodium symporter activity
ALANTH_RS10785	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALANTH_RS10790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALANTH_RS10795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALANTH_RS10800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALANTH_RS10805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALANTH_RS10810	COG1077	Cell shape determining protein MreB Mrl
ALANTH_RS10830	COG2239	Acts as a magnesium transporter
ALANTH_RS10835	COG0445	tRNA wobble uridine modification
ALANTH_RS10850	COG0148	phosphopyruvate hydratase activity
ALANTH_RS10885	COG0670	Belongs to the BI1 family
ALANTH_RS10890	COG0352	thiamine-phosphate diphosphorylase activity
ALANTH_RS10900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ALANTH_RS10905	COG0233	cytoplasmic translational termination
ALANTH_RS10910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALANTH_RS10920	COG2814	Major facilitator Superfamily
ALANTH_RS10925	COG0598	Magnesium transport protein CorA
ALANTH_RS10930	COG3022	response to hydroperoxide
ALANTH_RS10935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ALANTH_RS10955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALANTH_RS10960	COG1012	belongs to the aldehyde dehydrogenase family
ALANTH_RS10975	COG0783	Belongs to the Dps family
ALANTH_RS10980	COG2814	Major facilitator Superfamily
ALANTH_RS10985	COG0840	transmembrane signaling receptor activity
ALANTH_RS10995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALANTH_RS11000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALANTH_RS11015	COG2081	HI0933 family
ALANTH_RS11030	COG1959	2 iron, 2 sulfur cluster binding
ALANTH_RS11050	COG0175	sulfate reduction
ALANTH_RS11055	COG2895	sulfate adenylyltransferase (ATP) activity
ALANTH_RS11065	COG0133	tryptophan synthase activity
ALANTH_RS11080	COG1408	metallophosphoesterase
ALANTH_RS11100	COG1999	signal sequence binding
ALANTH_RS11110	COG2847	Copper chaperone PCu(A)C
ALANTH_RS11120	COG0840	transmembrane signaling receptor activity
ALANTH_RS11125	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALANTH_RS11130	COG4208	sulfate ABC transporter
ALANTH_RS11135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ALANTH_RS11140	COG2199	diguanylate cyclase activity
ALANTH_RS11140	COG2200	EAL domain
ALANTH_RS11140	COG3287	FIST C domain
ALANTH_RS11155	COG1045	serine acetyltransferase
ALANTH_RS11160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALANTH_RS11165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALANTH_RS11185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ALANTH_RS11190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALANTH_RS11205	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALANTH_RS11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALANTH_RS11220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ALANTH_RS11230	COG1116	anion transmembrane transporter activity
ALANTH_RS11235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALANTH_RS11240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALANTH_RS11245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ALANTH_RS11250	COG1126	abc transporter atp-binding protein
ALANTH_RS11255	COG0765	amino acid transport
ALANTH_RS11260	COG0765	amino acid transport
ALANTH_RS11275	COG1217	gtp-binding protein TYPA
ALANTH_RS11290	COG4771	TonB-dependent receptor
ALANTH_RS11295	COG4771	TonB-dependent receptor
ALANTH_RS11300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ALANTH_RS11305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALANTH_RS11310	COG4558	Periplasmic binding protein
ALANTH_RS11315	COG0748	coenzyme F420 binding
ALANTH_RS11325	COG1132	(ABC) transporter
ALANTH_RS11335	COG2391	methyltransferase activity
ALANTH_RS11340	COG0425	Belongs to the sulfur carrier protein TusA family
ALANTH_RS11355	COG1595	DNA-templated transcription, initiation
ALANTH_RS11360	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ALANTH_RS11365	COG2860	membrane
ALANTH_RS11395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group