locus-tag	class	description
ASKIR_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASKIR_RS00010	COG0592	DNA-directed DNA polymerase activity
ASKIR_RS00015	COG0187	DNA topoisomerase II activity
ASKIR_RS00020	COG0492	ferredoxin-NADP+ reductase activity
ASKIR_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASKIR_RS00040	COG0500	methyltransferase
ASKIR_RS00045	COG3842	ATPase activity
ASKIR_RS00085	COG0564	pseudouridine synthase activity
ASKIR_RS00090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASKIR_RS00095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASKIR_RS00100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASKIR_RS00110	COG0052	Belongs to the universal ribosomal protein uS2 family
ASKIR_RS00115	COG0604	alcohol dehydrogenase
ASKIR_RS00120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASKIR_RS00125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASKIR_RS00135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASKIR_RS00135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASKIR_RS00140	COG0511	ligase activity, forming carbon-carbon bonds
ASKIR_RS00145	COG0439	Biotin carboxylase
ASKIR_RS00150	COG0513	Belongs to the DEAD box helicase family
ASKIR_RS00155	COG0306	phosphate transporter
ASKIR_RS00165	COG0367	asparagine synthase
ASKIR_RS00175	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASKIR_RS00180	COG1981	membrane
ASKIR_RS00185	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ASKIR_RS00185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASKIR_RS00190	COG1187	pseudouridine synthase activity
ASKIR_RS00195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASKIR_RS00195	COG0517	IMP dehydrogenase activity
ASKIR_RS00200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASKIR_RS00205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASKIR_RS00210	COG0107	imidazoleglycerol-phosphate synthase activity
ASKIR_RS00225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASKIR_RS00230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASKIR_RS00235	COG0724	RNA recognition motif
ASKIR_RS00240	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS00245	COG0642	Histidine kinase
ASKIR_RS00265	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASKIR_RS00275	COG0460	homoserine dehydrogenase
ASKIR_RS00280	COG0436	Aminotransferase
ASKIR_RS00290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASKIR_RS00295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASKIR_RS00300	COG0254	rRNA binding
ASKIR_RS00305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASKIR_RS00315	COG0109	protoheme IX farnesyltransferase activity
ASKIR_RS00325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASKIR_RS00330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASKIR_RS00335	COG0573	inorganic phosphate transmembrane transporter activity
ASKIR_RS00340	COG0581	inorganic phosphate transmembrane transporter activity
ASKIR_RS00345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASKIR_RS00360	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS00365	COG5002	protein histidine kinase activity
ASKIR_RS00370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASKIR_RS00375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASKIR_RS00390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASKIR_RS00415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASKIR_RS00420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ASKIR_RS00430	COG0351	phosphomethylpyrimidine kinase
ASKIR_RS00430	COG0352	thiamine-phosphate diphosphorylase activity
ASKIR_RS00440	COG0546	phosphoglycolate phosphatase activity
ASKIR_RS00465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASKIR_RS00470	COG1854	S-ribosylhomocysteine lyase activity
ASKIR_RS00490	COG0646	methionine synthase
ASKIR_RS00490	COG1410	methionine synthase
ASKIR_RS00515	COG0140	phosphoribosyl-ATP diphosphatase activity
ASKIR_RS00515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASKIR_RS00530	COG0456	acetyltransferase
ASKIR_RS00535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASKIR_RS00540	COG1917	Cupin 2, conserved barrel domain protein
ASKIR_RS00555	COG0489	protein tyrosine kinase activity
ASKIR_RS00565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASKIR_RS00565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASKIR_RS00575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASKIR_RS00585	COG0505	Belongs to the CarA family
ASKIR_RS00595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASKIR_RS00600	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASKIR_RS00605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASKIR_RS00630	COG4895	conserved protein (DUF2196)
ASKIR_RS00635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASKIR_RS00640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASKIR_RS00645	COG0237	dephospho-CoA kinase activity
ASKIR_RS00655	COG0504	CTP synthase activity
ASKIR_RS00660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASKIR_RS00660	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ASKIR_RS00675	COG0693	protein deglycase activity
ASKIR_RS00680	COG0587	DNA-directed DNA polymerase activity
ASKIR_RS00685	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASKIR_RS00700	COG3040	lipid binding
ASKIR_RS00720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASKIR_RS00730	COG2200	EAL domain
ASKIR_RS00735	COG3279	Response regulator of the LytR AlgR family
ASKIR_RS00740	COG3275	phosphorelay sensor kinase activity
ASKIR_RS00745	COG1233	COG1233 Phytoene dehydrogenase and related
ASKIR_RS00750	COG0415	Belongs to the DNA photolyase family
ASKIR_RS00765	COG0315	cyclic pyranopterin monophosphate synthase activity
ASKIR_RS00770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASKIR_RS00775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASKIR_RS00780	COG0268	Binds directly to 16S ribosomal RNA
ASKIR_RS00785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASKIR_RS00790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASKIR_RS00795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASKIR_RS00800	COG0746	molybdenum cofactor guanylyltransferase activity
ASKIR_RS00815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASKIR_RS00820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASKIR_RS00825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASKIR_RS00830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASKIR_RS00850	COG0575	Belongs to the CDS family
ASKIR_RS00855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASKIR_RS00870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASKIR_RS00880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASKIR_RS00880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASKIR_RS00925	COG0511	ligase activity, forming carbon-carbon bonds
ASKIR_RS00925	COG5016	pyruvate
ASKIR_RS00940	COG0840	transmembrane signaling receptor activity
ASKIR_RS00950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASKIR_RS00955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASKIR_RS00965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASKIR_RS01000	COG0004	ammonium transporteR
ASKIR_RS01005	COG0347	Belongs to the P(II) protein family
ASKIR_RS01015	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASKIR_RS01020	COG1706	bacterial-type flagellum-dependent cell motility
ASKIR_RS01030	COG1987	bacterial-type flagellum assembly
ASKIR_RS01055	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASKIR_RS01085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASKIR_RS01095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASKIR_RS01100	COG0601	transmembrane transport
ASKIR_RS01105	COG0736	holo-[acyl-carrier-protein] synthase activity
ASKIR_RS01120	COG0786	glutamate:sodium symporter activity
ASKIR_RS01125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASKIR_RS01135	COG0560	Phosphoserine phosphatase
ASKIR_RS01140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASKIR_RS01145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ASKIR_RS01150	COG3248	Nucleoside-binding outer membrane protein
ASKIR_RS01155	COG1393	Belongs to the ArsC family
ASKIR_RS01160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASKIR_RS01165	COG0343	queuine tRNA-ribosyltransferase activity
ASKIR_RS01190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASKIR_RS01195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASKIR_RS01200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASKIR_RS01205	COG3278	Belongs to the heme-copper respiratory oxidase family
ASKIR_RS01260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASKIR_RS01275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASKIR_RS01285	COG0157	Belongs to the NadC ModD family
ASKIR_RS01300	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASKIR_RS01310	COG0083	homoserine kinase activity
ASKIR_RS01320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASKIR_RS01325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASKIR_RS01330	COG0779	Required for maturation of 30S ribosomal subunits
ASKIR_RS01335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASKIR_RS01335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASKIR_RS01340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASKIR_RS01345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASKIR_RS01350	COG0539	negative regulation of cytoplasmic translation
ASKIR_RS01350	COG1185	polyribonucleotide nucleotidyltransferase activity
ASKIR_RS01355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASKIR_RS01360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASKIR_RS01365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASKIR_RS01365	COG0072	phenylalanine-tRNA ligase activity
ASKIR_RS01370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASKIR_RS01375	COG0537	adenosine 5'-monophosphoramidase activity
ASKIR_RS01385	COG0825	malonyl-CoA metabolic process
ASKIR_RS01390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASKIR_RS01395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASKIR_RS01405	COG0602	queuosine metabolic process
ASKIR_RS01415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASKIR_RS01425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASKIR_RS01440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASKIR_RS01445	COG0723	plastoquinol--plastocyanin reductase activity
ASKIR_RS01450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASKIR_RS01455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASKIR_RS01460	COG0210	DNA helicase
ASKIR_RS01465	COG0356	it plays a direct role in the translocation of protons across the membrane
ASKIR_RS01470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASKIR_RS01475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASKIR_RS01485	COG0336	Belongs to the RNA methyltransferase TrmD family
ASKIR_RS01490	COG0335	large ribosomal subunit rRNA binding
ASKIR_RS01495	COG0586	Pfam SNARE associated Golgi protein
ASKIR_RS01500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASKIR_RS01515	COG0251	oxidation-reduction process
ASKIR_RS01530	COG2183	response to ionizing radiation
ASKIR_RS01555	COG0540	Belongs to the ATCase OTCase family
ASKIR_RS01560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASKIR_RS01565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASKIR_RS01570	COG2824	Alkylphosphonate utilization operon protein PhnA
ASKIR_RS01580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASKIR_RS01585	COG2205	protein histidine kinase activity
ASKIR_RS01590	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS01595	COG0628	permease
ASKIR_RS01610	COG0659	secondary active sulfate transmembrane transporter activity
ASKIR_RS01635	COG4771	TonB-dependent receptor
ASKIR_RS01645	COG1971	Probably functions as a manganese efflux pump
ASKIR_RS01665	COG2375	cellular response to nickel ion
ASKIR_RS01665	COG1132	(ABC) transporter
ASKIR_RS01670	COG4771	TonB-dependent receptor
ASKIR_RS01690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASKIR_RS01710	COG3043	anaerobic respiration
ASKIR_RS01715	COG0348	domain, Protein
ASKIR_RS01720	COG0437	4 iron, 4 sulfur cluster binding
ASKIR_RS01725	COG0243	molybdopterin cofactor binding
ASKIR_RS01740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASKIR_RS01745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASKIR_RS01755	COG2404	hydrolase activity, acting on ester bonds
ASKIR_RS01765	COG0642	Histidine kinase
ASKIR_RS01770	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS01775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASKIR_RS01780	COG0191	fructose-bisphosphate aldolase activity
ASKIR_RS01785	COG0039	L-malate dehydrogenase activity
ASKIR_RS01800	COG0848	biopolymer transport protein
ASKIR_RS01805	COG0811	peptide transport
ASKIR_RS01820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASKIR_RS01835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASKIR_RS01840	COG0442	prolyl-tRNA aminoacylation
ASKIR_RS01845	COG0668	transmembrane transport
ASKIR_RS01850	COG0617	tRNA 3'-terminal CCA addition
ASKIR_RS01865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASKIR_RS01870	COG1862	Preprotein translocase
ASKIR_RS01875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASKIR_RS01880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASKIR_RS01895	COG1360	Flagellar Motor Protein
ASKIR_RS01900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASKIR_RS01910	COG0495	leucyl-tRNA aminoacylation
ASKIR_RS01920	COG0285	dihydrofolate synthase activity
ASKIR_RS01950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASKIR_RS01975	COG0077	Prephenate dehydratase
ASKIR_RS01975	COG1605	Chorismate mutase
ASKIR_RS02020	COG0840	transmembrane signaling receptor activity
ASKIR_RS02030	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS02035	COG0642	Histidine kinase
ASKIR_RS02040	COG2081	HI0933 family
ASKIR_RS02045	COG0840	transmembrane signaling receptor activity
ASKIR_RS02060	COG5002	protein histidine kinase activity
ASKIR_RS02065	COG1692	metallophosphoesterase
ASKIR_RS02085	COG1570	exodeoxyribonuclease VII activity
ASKIR_RS02090	COG0835	chemotaxis
ASKIR_RS02095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASKIR_RS02100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASKIR_RS02105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASKIR_RS02120	COG0459	protein refolding
ASKIR_RS02130	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS02135	COG5002	protein histidine kinase activity
ASKIR_RS02145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASKIR_RS02155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASKIR_RS02160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASKIR_RS02170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASKIR_RS02180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASKIR_RS02185	COG2264	protein methyltransferase activity
ASKIR_RS02190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASKIR_RS02195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASKIR_RS02210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASKIR_RS02220	COG2095	MarC family integral membrane protein
ASKIR_RS02240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASKIR_RS02240	COG1648	precorrin-2 dehydrogenase activity
ASKIR_RS02250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASKIR_RS02250	COG1648	precorrin-2 dehydrogenase activity
ASKIR_RS02255	COG2078	PFAM AMMECR1 domain protein
ASKIR_RS02260	COG1355	regulation of microtubule-based process
ASKIR_RS02265	COG0840	transmembrane signaling receptor activity
ASKIR_RS02270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASKIR_RS02275	COG1121	(ABC) transporter
ASKIR_RS02280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASKIR_RS02285	COG2996	Protein conserved in bacteria
ASKIR_RS02290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASKIR_RS02300	COG0210	DNA helicase
ASKIR_RS02305	COG0569	domain protein
ASKIR_RS02305	COG0475	glutathione-regulated potassium exporter activity
ASKIR_RS02310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ASKIR_RS02370	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASKIR_RS02375	COG4608	Belongs to the ABC transporter superfamily
ASKIR_RS02380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASKIR_RS02385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASKIR_RS02415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASKIR_RS02420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASKIR_RS02435	COG0250	Participates in transcription elongation, termination and antitermination
ASKIR_RS02440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASKIR_RS02445	COG0081	regulation of translation
ASKIR_RS02450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASKIR_RS02455	COG0222	ribosome binding
ASKIR_RS02460	COG0085	RNA polymerase activity
ASKIR_RS02465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASKIR_RS02485	COG0739	heme binding
ASKIR_RS02485	COG0741	lytic transglycosylase activity
ASKIR_RS02485	COG1196	nuclear chromosome segregation
ASKIR_RS02495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASKIR_RS02500	COG0138	bifunctional purine biosynthesis protein purh
ASKIR_RS02510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASKIR_RS02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASKIR_RS02535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASKIR_RS02550	COG2326	polyphosphate kinase activity
ASKIR_RS02555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASKIR_RS02560	COG0571	ribonuclease III activity
ASKIR_RS02570	COG0358	DNA primase activity
ASKIR_RS02575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASKIR_RS02580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASKIR_RS02585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASKIR_RS02590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASKIR_RS02595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASKIR_RS02605	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASKIR_RS02605	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASKIR_RS02610	COG1192	Involved in chromosome partitioning
ASKIR_RS02615	COG1475	DNA binding
ASKIR_RS02625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASKIR_RS02630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASKIR_RS02635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASKIR_RS02640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASKIR_RS02645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASKIR_RS02650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASKIR_RS02655	COG0811	peptide transport
ASKIR_RS02660	COG0848	biopolymer transport protein
ASKIR_RS02670	COG0823	Involved in the tonB-independent uptake of proteins
ASKIR_RS02685	COG1047	Peptidyl-prolyl cis-trans
ASKIR_RS02690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASKIR_RS02695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASKIR_RS02700	COG1027	Aspartate ammonia-lyase
ASKIR_RS02725	COG1227	inorganic diphosphatase activity
ASKIR_RS02730	COG0668	transmembrane transport
ASKIR_RS02735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASKIR_RS02745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASKIR_RS02750	COG0010	Belongs to the arginase family
ASKIR_RS02755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASKIR_RS02760	COG1278	Cold shock
ASKIR_RS02765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASKIR_RS02770	COG0581	inorganic phosphate transmembrane transporter activity
ASKIR_RS02775	COG0573	inorganic phosphate transmembrane transporter activity
ASKIR_RS02780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASKIR_RS02785	COG4335	DNA alkylation repair
ASKIR_RS02790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASKIR_RS02810	COG0753	catalase activity
ASKIR_RS02835	COG4753	response regulator
ASKIR_RS02835	COG2207	Transcriptional regulator
ASKIR_RS02840	COG4191	Histidine kinase
ASKIR_RS02845	COG0348	domain, Protein
ASKIR_RS02850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASKIR_RS02860	COG0840	transmembrane signaling receptor activity
ASKIR_RS02865	COG0840	transmembrane signaling receptor activity
ASKIR_RS02870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASKIR_RS02875	COG0750	zinc metalloprotease
ASKIR_RS02880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASKIR_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
ASKIR_RS02890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASKIR_RS02900	COG0167	dihydroorotate dehydrogenase activity
ASKIR_RS02905	COG1132	(ABC) transporter
ASKIR_RS02910	COG0728	peptidoglycan biosynthetic process
ASKIR_RS02925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASKIR_RS02935	COG0789	Transcriptional regulator
ASKIR_RS02940	COG0484	heat shock protein binding
ASKIR_RS02965	COG0326	Molecular chaperone. Has ATPase activity
ASKIR_RS02975	COG0513	Belongs to the DEAD box helicase family
ASKIR_RS02990	COG0259	pyridoxamine-phosphate oxidase activity
ASKIR_RS02995	COG1078	dGTPase activity
ASKIR_RS03005	COG3287	FIST C domain
ASKIR_RS03005	COG2200	EAL domain
ASKIR_RS03005	COG2199	diguanylate cyclase activity
ASKIR_RS03070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASKIR_RS03075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASKIR_RS03075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASKIR_RS03090	COG1090	epimerase
ASKIR_RS03095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASKIR_RS03125	COG0730	response to heat
ASKIR_RS03130	COG1045	serine acetyltransferase
ASKIR_RS03135	COG1166	arginine decarboxylase activity
ASKIR_RS03140	COG0124	histidyl-tRNA synthetase
ASKIR_RS03145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASKIR_RS03150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASKIR_RS03155	COG0163	prenyltransferase activity
ASKIR_RS03165	COG0359	binds to the 23S rRNA
ASKIR_RS03170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASKIR_RS03175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASKIR_RS03185	COG0084	hydrolase, TatD family'
ASKIR_RS03190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASKIR_RS03195	COG0131	Imidazoleglycerol-phosphate dehydratase
ASKIR_RS03200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASKIR_RS03215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASKIR_RS03220	COG0456	acetyltransferase
ASKIR_RS03225	COG0051	transcription antitermination factor activity, RNA binding
ASKIR_RS03230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASKIR_RS03235	COG0088	Forms part of the polypeptide exit tunnel
ASKIR_RS03240	COG0089	rRNA binding
ASKIR_RS03245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASKIR_RS03250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASKIR_RS03255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASKIR_RS03260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASKIR_RS03265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASKIR_RS03270	COG0255	Belongs to the universal ribosomal protein uL29 family
ASKIR_RS03275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASKIR_RS03280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASKIR_RS03285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASKIR_RS03290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASKIR_RS03295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASKIR_RS03300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASKIR_RS03305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASKIR_RS03310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASKIR_RS03315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASKIR_RS03320	COG0200	Binds to the 23S rRNA
ASKIR_RS03325	COG0201	protein transport
ASKIR_RS03330	COG0024	Methionine aminopeptidase
ASKIR_RS03335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASKIR_RS03340	COG1573	uracil-dna glycosylase
ASKIR_RS03350	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASKIR_RS03355	COG1032	radical SAM domain protein
ASKIR_RS03360	COG0563	adenylate kinase activity
ASKIR_RS03365	COG0563	adenylate kinase activity
ASKIR_RS03390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASKIR_RS03395	COG0840	transmembrane signaling receptor activity
ASKIR_RS03400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASKIR_RS03405	COG0322	excinuclease ABC activity
ASKIR_RS03420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASKIR_RS03430	COG0784	Response regulator, receiver
ASKIR_RS03430	COG3437	response regulator, receiver
ASKIR_RS03435	COG1338	Plays a role in the flagellum-specific transport system
ASKIR_RS03440	COG0768	penicillin binding
ASKIR_RS03460	COG2884	Cell division ATP-binding protein ftsE
ASKIR_RS03465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASKIR_RS03475	COG0564	pseudouridine synthase activity
ASKIR_RS03480	COG0772	Belongs to the SEDS family
ASKIR_RS03490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASKIR_RS03495	COG3123	guanosine phosphorylase activity
ASKIR_RS03515	COG1278	Cold shock
ASKIR_RS03525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASKIR_RS03530	COG0066	3-isopropylmalate dehydratase activity
ASKIR_RS03535	COG0473	3-isopropylmalate dehydrogenase activity
ASKIR_RS03550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASKIR_RS03555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASKIR_RS03560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASKIR_RS03565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASKIR_RS03570	COG0202	RNA polymerase activity
ASKIR_RS03575	COG0203	ribosomal protein L17
ASKIR_RS03580	COG0154	amidase activity
ASKIR_RS03585	COG0516	GMP reductase activity
ASKIR_RS03585	COG0517	IMP dehydrogenase activity
ASKIR_RS03600	COG0484	heat shock protein binding
ASKIR_RS03605	COG0484	heat shock protein binding
ASKIR_RS03615	COG0513	Belongs to the DEAD box helicase family
ASKIR_RS03620	COG2217	Heavy metal translocating P-type atpase
ASKIR_RS03630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASKIR_RS03635	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASKIR_RS03640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASKIR_RS03645	COG0095	Lipoate-protein ligase
ASKIR_RS03650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASKIR_RS03655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASKIR_RS03660	COG0840	transmembrane signaling receptor activity
ASKIR_RS03665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASKIR_RS03670	COG1944	ATP diphosphatase activity
ASKIR_RS03675	COG2258	MOSC domain
ASKIR_RS03680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASKIR_RS03690	COG3135	benzoate transporter
ASKIR_RS03695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASKIR_RS03695	COG2169	Transcriptional regulator
ASKIR_RS03700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASKIR_RS03725	COG4536	flavin adenine dinucleotide binding
ASKIR_RS03730	COG0628	permease
ASKIR_RS03750	COG4974	Belongs to the 'phage' integrase family
ASKIR_RS03930	COG0653	protein targeting
ASKIR_RS03945	COG3328	transposase activity
ASKIR_RS04075	COG3179	chitinase
ASKIR_RS04095	COG3179	chitinase
ASKIR_RS04120	COG0420	3'-5' exonuclease activity
ASKIR_RS04125	COG0419	ATPase involved in DNA repair
ASKIR_RS04150	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ASKIR_RS04220	COG0284	orotidine-5'-phosphate decarboxylase activity
ASKIR_RS04225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASKIR_RS04230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASKIR_RS04240	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASKIR_RS04250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASKIR_RS04260	COG1295	ribonuclease BN
ASKIR_RS04265	COG0277	FAD linked oxidase domain protein
ASKIR_RS04275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASKIR_RS04280	COG2226	methyltransferase
ASKIR_RS04310	COG1739	Uncharacterized protein family UPF0029
ASKIR_RS04330	COG0301	tRNA thio-modification
ASKIR_RS04330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASKIR_RS04345	COG2814	Major facilitator Superfamily
ASKIR_RS04420	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ASKIR_RS04455	COG0330	HflC and HflK could
ASKIR_RS04480	COG2081	HI0933 family
ASKIR_RS04510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASKIR_RS04515	COG2171	N-acyltransferase activity
ASKIR_RS04520	COG0488	(ABC) transporter
ASKIR_RS04595	COG1137	ATPase activity
ASKIR_RS04605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASKIR_RS04610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASKIR_RS04615	COG0137	argininosuccinate synthase activity
ASKIR_RS04630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASKIR_RS04640	COG0776	regulation of translation
ASKIR_RS04645	COG0708	Exodeoxyribonuclease III
ASKIR_RS04675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASKIR_RS04685	COG2204	response regulator
ASKIR_RS04695	COG0166	Belongs to the GPI family
ASKIR_RS04735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASKIR_RS04765	COG1858	cytochrome C peroxidase
ASKIR_RS04775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASKIR_RS04785	COG1921	L-seryl-tRNASec selenium transferase activity
ASKIR_RS04810	COG0450	alkyl hydroperoxide reductase
ASKIR_RS04815	COG0840	transmembrane signaling receptor activity
ASKIR_RS04820	COG0840	transmembrane signaling receptor activity
ASKIR_RS04825	COG0709	Synthesizes selenophosphate from selenide and ATP
ASKIR_RS04830	COG1305	Transglutaminase-like
ASKIR_RS04850	COG2204	response regulator
ASKIR_RS04890	COG0437	4 iron, 4 sulfur cluster binding
ASKIR_RS04900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASKIR_RS04920	COG0303	'Molybdopterin
ASKIR_RS04925	COG2998	abc-type tungstate transport system, permease component
ASKIR_RS04930	COG4662	Binding-protein-dependent transport system inner membrane component
ASKIR_RS04945	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASKIR_RS04960	COG1132	(ABC) transporter
ASKIR_RS04970	COG0596	Alpha beta hydrolase
ASKIR_RS04995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASKIR_RS04995	COG0519	Catalyzes the synthesis of GMP from XMP
ASKIR_RS05000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASKIR_RS05015	COG0436	Aminotransferase
ASKIR_RS05030	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASKIR_RS05035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASKIR_RS05035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASKIR_RS05055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASKIR_RS05060	COG1611	Belongs to the LOG family
ASKIR_RS05080	COG0739	heme binding
ASKIR_RS05085	COG0217	transcriptional regulatory protein
ASKIR_RS05105	COG0428	transporter
ASKIR_RS05110	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASKIR_RS05115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASKIR_RS05115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASKIR_RS05160	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASKIR_RS05165	COG5016	pyruvate
ASKIR_RS05165	COG0511	ligase activity, forming carbon-carbon bonds
ASKIR_RS05185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASKIR_RS05185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASKIR_RS05195	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASKIR_RS05220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASKIR_RS05225	COG0612	Peptidase, M16
ASKIR_RS05230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ASKIR_RS05235	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASKIR_RS05240	COG0287	Prephenate dehydrogenase
ASKIR_RS05245	COG0386	Belongs to the glutathione peroxidase family
ASKIR_RS05250	COG4221	oxidoreductase activity
ASKIR_RS05275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASKIR_RS05285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASKIR_RS05300	COG0527	aspartate kinase activity
ASKIR_RS05305	COG0494	nUDIX hydrolase
ASKIR_RS05310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASKIR_RS05315	COG2890	protein-(glutamine-N5) methyltransferase activity
ASKIR_RS05320	COG0339	signal peptide processing
ASKIR_RS05335	COG0582	viral genome integration into host DNA
ASKIR_RS05340	COG2201	protein-glutamate methylesterase activity
ASKIR_RS05355	COG2198	Histidine kinase
ASKIR_RS05355	COG0643	Histidine kinase
ASKIR_RS05360	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS05365	COG1185	polyribonucleotide nucleotidyltransferase activity
ASKIR_RS05395	COG1160	GTP binding
ASKIR_RS05400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASKIR_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
ASKIR_RS05410	COG1674	ftsk spoiiie
ASKIR_RS05410	COG1196	nuclear chromosome segregation
ASKIR_RS05415	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASKIR_RS05420	COG0440	acetolactate synthase activity
ASKIR_RS05425	COG0028	Belongs to the TPP enzyme family
ASKIR_RS05435	COG0248	Ppx GppA phosphatase
ASKIR_RS05460	COG0037	tRNA processing
ASKIR_RS05480	COG0501	Belongs to the peptidase M48B family
ASKIR_RS05485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASKIR_RS05490	COG0824	Thioesterase
ASKIR_RS05500	COG1663	tetraacyldisaccharide 4'-kinase activity
ASKIR_RS05505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASKIR_RS05510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASKIR_RS05530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASKIR_RS05535	COG0805	protein transport
ASKIR_RS05540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASKIR_RS05580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASKIR_RS05595	COG0840	transmembrane signaling receptor activity
ASKIR_RS05615	COG0357	Ribosomal RNA small subunit methyltransferase G
ASKIR_RS05620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASKIR_RS05625	COG0113	porphobilinogen synthase activity
ASKIR_RS05640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASKIR_RS05645	COG2337	Toxic component of a toxin-antitoxin (TA) module
ASKIR_RS05655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASKIR_RS05660	COG1396	sequence-specific DNA binding
ASKIR_RS05675	COG1216	Glycosyl transferase, family 2
ASKIR_RS05675	COG0463	Glycosyl transferase, family 2
ASKIR_RS05695	COG2244	polysaccharide biosynthetic process
ASKIR_RS05730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASKIR_RS05815	COG0667	Aldo Keto reductase
ASKIR_RS05840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASKIR_RS05845	COG0484	heat shock protein binding
ASKIR_RS05855	COG2111	Na H antiporter
ASKIR_RS05855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASKIR_RS05860	COG1006	Multisubunit Na H antiporter MnhC subunit
ASKIR_RS05865	COG0651	ATP synthesis coupled electron transport
ASKIR_RS05870	COG1863	multisubunit Na H antiporter MnhE subunit
ASKIR_RS05875	COG2212	antiporter activity
ASKIR_RS05880	COG1320	monovalent cation:proton antiporter activity
ASKIR_RS05890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASKIR_RS05900	COG0500	methyltransferase
ASKIR_RS05905	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASKIR_RS05910	COG1333	cytochrome c biogenesis protein
ASKIR_RS05910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASKIR_RS05920	COG0135	phosphoribosylanthranilate isomerase activity
ASKIR_RS05925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASKIR_RS05945	COG1666	GTP binding
ASKIR_RS05950	COG2363	Small membrane protein
ASKIR_RS05955	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASKIR_RS05960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASKIR_RS05965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASKIR_RS05980	COG1119	ATPase activity
ASKIR_RS05990	COG1253	flavin adenine dinucleotide binding
ASKIR_RS05995	COG1193	negative regulation of DNA recombination
ASKIR_RS06000	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASKIR_RS06010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASKIR_RS06015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASKIR_RS06025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASKIR_RS06035	COG4139	cobalamin transport
ASKIR_RS06045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASKIR_RS06065	COG0546	phosphoglycolate phosphatase activity
ASKIR_RS06070	COG1187	pseudouridine synthase activity
ASKIR_RS06075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASKIR_RS06105	COG0328	RNA-DNA hybrid ribonuclease activity
ASKIR_RS06110	COG0488	(ABC) transporter
ASKIR_RS06120	COG0739	heme binding
ASKIR_RS06130	COG0134	indole-3-glycerol-phosphate synthase activity
ASKIR_RS06140	COG0727	PFAM Uncharacterised protein family (UPF0153)
ASKIR_RS06145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASKIR_RS06155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASKIR_RS06155	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASKIR_RS06160	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASKIR_RS06180	COG0653	protein targeting
ASKIR_RS06185	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASKIR_RS06225	COG0275	rRNA processing
ASKIR_RS06235	COG0776	regulation of translation
ASKIR_RS06250	COG0300	oxidoreductase activity
ASKIR_RS06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASKIR_RS06280	COG0742	ribosomal rna small subunit methyltransferase
ASKIR_RS06285	COG1418	mRNA catabolic process
ASKIR_RS06300	COG0552	protein localization to endoplasmic reticulum
ASKIR_RS06315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASKIR_RS06320	COG0861	Integral membrane protein TerC family
ASKIR_RS06325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASKIR_RS06335	COG5002	protein histidine kinase activity
ASKIR_RS06340	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS06350	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASKIR_RS06360	COG1114	Component of the transport system for branched-chain amino acids
ASKIR_RS06365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASKIR_RS06370	COG0788	formyltetrahydrofolate deformylase activity
ASKIR_RS06375	COG0280	phosphate acetyltransferase
ASKIR_RS06375	COG0281	malic enzyme
ASKIR_RS06380	COG1496	oxidoreductase activity
ASKIR_RS06385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASKIR_RS06390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASKIR_RS06400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASKIR_RS06410	COG0514	ATP-dependent DNA helicase (RecQ)
ASKIR_RS06415	COG0582	viral genome integration into host DNA
ASKIR_RS06550	COG0629	single-stranded DNA binding
ASKIR_RS06565	COG3451	type IV secretory pathway VirB4
ASKIR_RS06595	COG2948	multi-organism process
ASKIR_RS06605	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ASKIR_RS06625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASKIR_RS06630	COG1722	exodeoxyribonuclease VII activity
ASKIR_RS06635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASKIR_RS06645	COG2391	methyltransferase activity
ASKIR_RS06655	COG0849	cell division
ASKIR_RS06665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASKIR_RS06675	COG0513	Belongs to the DEAD box helicase family
ASKIR_RS06685	COG0754	glutathionylspermidine amidase activity
ASKIR_RS06690	COG1607	acyl-coa hydrolase
ASKIR_RS06695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASKIR_RS06705	COG0577	efflux transmembrane transporter activity
ASKIR_RS06705	COG1136	(ABC) transporter
ASKIR_RS06710	COG0577	efflux transmembrane transporter activity
ASKIR_RS06710	COG1136	(ABC) transporter
ASKIR_RS06715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASKIR_RS06730	COG0848	biopolymer transport protein
ASKIR_RS06740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASKIR_RS06750	COG0133	tryptophan synthase activity
ASKIR_RS06755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASKIR_RS06760	COG1793	dna ligase
ASKIR_RS06765	COG0626	cystathionine gamma-synthase activity
ASKIR_RS06795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ASKIR_RS06800	COG0803	Belongs to the bacterial solute-binding protein 9 family
ASKIR_RS06810	COG0528	UMP kinase activity
ASKIR_RS06815	COG1758	RNA polymerase activity
ASKIR_RS06825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASKIR_RS06835	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASKIR_RS06850	COG0193	aminoacyl-tRNA hydrolase activity
ASKIR_RS06855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASKIR_RS06860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASKIR_RS06865	COG0681	Belongs to the peptidase S26 family
ASKIR_RS06870	COG0698	ribose 5-phosphate isomerase
ASKIR_RS06885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASKIR_RS06890	COG0784	Response regulator, receiver
ASKIR_RS06890	COG2198	Histidine kinase
ASKIR_RS06890	COG5002	protein histidine kinase activity
ASKIR_RS06895	COG2203	Gaf domain
ASKIR_RS06895	COG3706	GGDEF domain
ASKIR_RS06895	COG4251	negative regulation of phosphorylation
ASKIR_RS06895	COG5001	Diguanylate cyclase
ASKIR_RS06900	COG0556	nucleotide-excision repair
ASKIR_RS06910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASKIR_RS06915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASKIR_RS06920	COG0784	Response regulator, receiver
ASKIR_RS06920	COG0835	chemotaxis
ASKIR_RS06925	COG0165	Argininosuccinate lyase
ASKIR_RS06935	COG2239	Acts as a magnesium transporter
ASKIR_RS06945	COG0719	Fe-S assembly protein
ASKIR_RS06950	COG0396	ATPase activity
ASKIR_RS06955	COG0719	Fe-S assembly protein
ASKIR_RS06960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASKIR_RS06965	COG2166	iron-sulfur cluster assembly
ASKIR_RS06990	COG4773	Receptor
ASKIR_RS06995	COG0439	Biotin carboxylase
ASKIR_RS07005	COG3077	Addiction module antitoxin, RelB DinJ family
ASKIR_RS07035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASKIR_RS07045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASKIR_RS07065	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASKIR_RS07070	COG2814	Major facilitator Superfamily
ASKIR_RS07085	COG0525	valine-tRNA ligase activity
ASKIR_RS07105	COG0174	glutamine synthetase
ASKIR_RS07115	COG0314	molybdopterin synthase activity
ASKIR_RS07125	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ASKIR_RS07130	COG1968	undecaprenyl-diphosphatase activity
ASKIR_RS07145	COG1373	ATPase (AAA superfamily
ASKIR_RS07150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASKIR_RS07155	COG0772	Belongs to the SEDS family
ASKIR_RS07160	COG0768	penicillin binding
ASKIR_RS07165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASKIR_RS07210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASKIR_RS07220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASKIR_RS07235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASKIR_RS07245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASKIR_RS07255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASKIR_RS07265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASKIR_RS07265	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASKIR_RS07270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASKIR_RS07280	COG1368	sulfuric ester hydrolase activity
ASKIR_RS07300	COG0463	Glycosyl transferase, family 2
ASKIR_RS07335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASKIR_RS07345	COG0859	PFAM glycosyl transferase family 9
ASKIR_RS07355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASKIR_RS07360	COG0483	inositol monophosphate 1-phosphatase activity
ASKIR_RS07385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASKIR_RS07395	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASKIR_RS07400	COG0632	four-way junction helicase activity
ASKIR_RS07405	COG0840	transmembrane signaling receptor activity
ASKIR_RS07415	COG0585	pseudouridine synthase activity
ASKIR_RS07420	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASKIR_RS07425	COG3123	guanosine phosphorylase activity
ASKIR_RS07440	COG1639	'signal transduction protein
ASKIR_RS07445	COG0012	GTP binding
ASKIR_RS07450	COG1966	Carbon starvation protein
ASKIR_RS07480	COG0305	Participates in initiation and elongation during chromosome replication
ASKIR_RS07485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASKIR_RS07500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASKIR_RS07505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASKIR_RS07515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASKIR_RS07520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASKIR_RS07525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASKIR_RS07535	COG3706	GGDEF domain
ASKIR_RS07540	COG0501	Belongs to the peptidase M48B family
ASKIR_RS07555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASKIR_RS07565	COG0706	membrane insertase activity
ASKIR_RS07570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASKIR_RS07580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASKIR_RS07585	COG0542	response to heat
ASKIR_RS07665	COG3210	domain, Protein
ASKIR_RS07665	COG3210	domain, Protein
ASKIR_RS07670	COG2831	hemolysin activation secretion protein
ASKIR_RS07675	COG0488	(ABC) transporter
ASKIR_RS07685	COG0778	Nitroreductase
ASKIR_RS07690	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASKIR_RS07720	COG2855	membrane
ASKIR_RS07725	COG0583	DNA-binding transcription factor activity
ASKIR_RS07735	COG2076	Multidrug Resistance protein
ASKIR_RS07740	COG0642	Histidine kinase
ASKIR_RS07755	COG3258	Cytochrome c
ASKIR_RS07800	COG0628	permease
ASKIR_RS07805	COG2255	four-way junction helicase activity
ASKIR_RS07810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASKIR_RS07815	COG0159	tryptophan synthase activity
ASKIR_RS07820	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASKIR_RS07825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ASKIR_RS07850	COG0598	Magnesium transport protein CorA
ASKIR_RS07855	COG1459	type II secretion system
ASKIR_RS07860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASKIR_RS07875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASKIR_RS07880	COG0606	chelatase, subunit chli
ASKIR_RS07885	COG0840	transmembrane signaling receptor activity
ASKIR_RS07890	COG0840	transmembrane signaling receptor activity
ASKIR_RS07900	COG0242	peptide deformylase activity
ASKIR_RS07905	COG0740	serine-type endopeptidase activity
ASKIR_RS07910	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASKIR_RS07915	COG2326	polyphosphate kinase activity
ASKIR_RS07975	COG0542	response to heat
ASKIR_RS07980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASKIR_RS07985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASKIR_RS08000	COG2030	dehydratase
ASKIR_RS08040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASKIR_RS08050	COG0481	GTPase activity
ASKIR_RS08055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASKIR_RS08060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASKIR_RS08065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASKIR_RS08070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASKIR_RS08090	COG2217	Heavy metal translocating P-type atpase
ASKIR_RS08095	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASKIR_RS08100	COG0194	GDP metabolic process
ASKIR_RS08110	COG1136	(ABC) transporter
ASKIR_RS08115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASKIR_RS08120	COG0052	Belongs to the universal ribosomal protein uS2 family
ASKIR_RS08125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASKIR_RS08140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASKIR_RS08145	COG0579	oxidoreductase
ASKIR_RS08195	COG0642	Histidine kinase
ASKIR_RS08200	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS08215	COG2176	DNA-directed DNA polymerase activity
ASKIR_RS08225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASKIR_RS08245	COG2176	DNA-directed DNA polymerase activity
ASKIR_RS08255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASKIR_RS08260	COG0280	phosphate acetyltransferase
ASKIR_RS08265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASKIR_RS08270	COG0616	signal peptide processing
ASKIR_RS08275	COG0402	S-adenosylhomocysteine deaminase activity
ASKIR_RS08280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASKIR_RS08285	COG0006	proline dipeptidase activity
ASKIR_RS08290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASKIR_RS08295	COG0482	sulfurtransferase activity
ASKIR_RS08300	COG0482	sulfurtransferase activity
ASKIR_RS08305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASKIR_RS08315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASKIR_RS08325	COG1157	protein secretion by the type III secretion system
ASKIR_RS08335	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASKIR_RS08365	COG0455	bacterial-type flagellum organization
ASKIR_RS08370	COG1419	protein localization to endoplasmic reticulum
ASKIR_RS08385	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASKIR_RS08430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASKIR_RS08440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASKIR_RS08445	COG1766	The M ring may be actively involved in energy transduction
ASKIR_RS08450	COG1815	bacterial-type flagellum-dependent cell motility
ASKIR_RS08455	COG4786	Flagellar basal body rod
ASKIR_RS08465	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS08470	COG4786	Flagellar basal body rod
ASKIR_RS08485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASKIR_RS08495	COG0228	four-way junction DNA binding
ASKIR_RS08500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASKIR_RS08505	COG0564	pseudouridine synthase activity
ASKIR_RS08510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASKIR_RS08510	COG1519	Transferase
ASKIR_RS08520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASKIR_RS08525	COG0752	glycyl-tRNA synthetase alpha subunit
ASKIR_RS08535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASKIR_RS08545	COG0826	peptidase U32
ASKIR_RS08550	COG0840	transmembrane signaling receptor activity
ASKIR_RS08555	COG0497	DNA recombination
ASKIR_RS08560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASKIR_RS08565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASKIR_RS08570	COG0049	tRNA binding
ASKIR_RS08575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASKIR_RS08595	COG1840	ABC-type Fe3 transport system, periplasmic component
ASKIR_RS08605	COG3842	ATPase activity
ASKIR_RS08610	COG1393	Belongs to the ArsC family
ASKIR_RS08615	COG1335	isochorismatase
ASKIR_RS08620	COG0181	hydroxymethylbilane synthase activity
ASKIR_RS08625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASKIR_RS08630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASKIR_RS08635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASKIR_RS08640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASKIR_RS08645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASKIR_RS08650	COG0450	alkyl hydroperoxide reductase
ASKIR_RS08660	COG0105	UTP biosynthetic process
ASKIR_RS08670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASKIR_RS08675	COG0416	fatty acid biosynthetic process
ASKIR_RS08680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASKIR_RS08700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASKIR_RS08705	COG1053	succinate dehydrogenase
ASKIR_RS08715	COG1007	ATP synthesis coupled electron transport
ASKIR_RS08725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASKIR_RS08730	COG0713	ATP synthesis coupled electron transport
ASKIR_RS08735	COG0839	Belongs to the complex I subunit 6 family
ASKIR_RS08740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASKIR_RS08745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASKIR_RS08750	COG1034	ATP synthesis coupled electron transport
ASKIR_RS08755	COG0372	Belongs to the citrate synthase family
ASKIR_RS08765	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ASKIR_RS08770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASKIR_RS08770	COG0649	NAD binding
ASKIR_RS08775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASKIR_RS08780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASKIR_RS08785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASKIR_RS08800	COG0840	transmembrane signaling receptor activity
ASKIR_RS08805	COG2199	diguanylate cyclase activity
ASKIR_RS08805	COG2200	EAL domain
ASKIR_RS08805	COG3287	FIST C domain
ASKIR_RS08815	COG3610	response to peptide
ASKIR_RS08820	COG3610	response to peptide
ASKIR_RS08830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASKIR_RS08835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASKIR_RS08845	COG0840	transmembrane signaling receptor activity
ASKIR_RS08870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASKIR_RS08880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASKIR_RS08890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASKIR_RS08895	COG2828	Protein conserved in bacteria
ASKIR_RS08900	COG0741	lytic transglycosylase activity
ASKIR_RS08905	COG0469	pyruvate kinase activity
ASKIR_RS08915	COG0792	nuclease activity
ASKIR_RS08920	COG0156	8-amino-7-oxononanoate synthase activity
ASKIR_RS08925	COG0288	reversible hydration of carbon dioxide
ASKIR_RS08935	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ASKIR_RS08945	COG2121	Domain of unknown function (DUF374)
ASKIR_RS08950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASKIR_RS08960	COG0195	Participates in both transcription termination and antitermination
ASKIR_RS08965	COG0215	cysteine-tRNA ligase activity
ASKIR_RS08970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASKIR_RS08975	COG0629	single-stranded DNA binding
ASKIR_RS08980	COG0360	Binds together with S18 to 16S ribosomal RNA
ASKIR_RS08995	COG0557	exoribonuclease II activity
ASKIR_RS09000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASKIR_RS09015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASKIR_RS09020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASKIR_RS09025	COG0492	ferredoxin-NADP+ reductase activity
ASKIR_RS09030	COG3118	belongs to the thioredoxin family
ASKIR_RS09035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASKIR_RS09045	COG4771	TonB-dependent receptor
ASKIR_RS09050	COG0642	Histidine kinase
ASKIR_RS09055	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS09065	COG0129	dihydroxy-acid dehydratase activity
ASKIR_RS09085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASKIR_RS09090	COG0585	pseudouridine synthase activity
ASKIR_RS09105	COG0793	Belongs to the peptidase S41A family
ASKIR_RS09110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASKIR_RS09115	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASKIR_RS09120	COG0047	phosphoribosylformylglycinamidine synthase activity
ASKIR_RS09130	COG0204	Acyl-transferase
ASKIR_RS09135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASKIR_RS09140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASKIR_RS09145	COG0018	arginyl-trna synthetase
ASKIR_RS09155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASKIR_RS09160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASKIR_RS09165	COG0126	phosphoglycerate kinase activity
ASKIR_RS09170	COG0149	triose-phosphate isomerase activity
ASKIR_RS09175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASKIR_RS09180	COG0019	diaminopimelate decarboxylase activity
ASKIR_RS09185	COG0077	Prephenate dehydratase
ASKIR_RS09185	COG1605	Chorismate mutase
ASKIR_RS09190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASKIR_RS09195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASKIR_RS09200	COG1858	cytochrome C peroxidase
ASKIR_RS09210	COG0424	maF-like protein
ASKIR_RS09240	COG0189	ligase activity
ASKIR_RS09255	COG2199	diguanylate cyclase activity
ASKIR_RS09255	COG2200	EAL domain
ASKIR_RS09255	COG3287	FIST C domain
ASKIR_RS09275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASKIR_RS09280	COG0443	Heat shock 70 kDa protein
ASKIR_RS09285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASKIR_RS09310	COG0310	cobalt ion transport
ASKIR_RS09325	COG0309	Hydrogenase expression formation protein (HypE)
ASKIR_RS09330	COG0409	Hydrogenase expression formation protein
ASKIR_RS09335	COG0298	carbon dioxide binding
ASKIR_RS09340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASKIR_RS09350	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASKIR_RS09355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASKIR_RS09360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASKIR_RS09365	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ASKIR_RS09370	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ASKIR_RS09375	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASKIR_RS09395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASKIR_RS09400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASKIR_RS09405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASKIR_RS09415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASKIR_RS09420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASKIR_RS09485	COG2226	methyltransferase
ASKIR_RS09505	COG1216	Glycosyl transferase, family 2
ASKIR_RS09505	COG1442	glycosyl transferase family 8
ASKIR_RS09525	COG1454	alcohol dehydrogenase
ASKIR_RS09545	COG0204	Acyl-transferase
ASKIR_RS09545	COG0318	PFAM AMP-dependent synthetase and ligase
ASKIR_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
ASKIR_RS09575	COG2089	acid synthase
ASKIR_RS09585	COG1083	cytidylyl-transferase
ASKIR_RS09590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASKIR_RS09595	COG1086	Polysaccharide biosynthesis protein
ASKIR_RS09605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASKIR_RS09610	COG0733	neurotransmitter:sodium symporter activity
ASKIR_RS09615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASKIR_RS09620	COG0659	secondary active sulfate transmembrane transporter activity
ASKIR_RS09630	COG1222	aaa ATPase
ASKIR_RS09640	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ASKIR_RS09645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASKIR_RS09665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASKIR_RS09670	COG0148	phosphopyruvate hydratase activity
ASKIR_RS09745	COG0464	growth
ASKIR_RS09775	COG0445	tRNA wobble uridine modification
ASKIR_RS09790	COG1077	Cell shape determining protein MreB Mrl
ASKIR_RS09795	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASKIR_RS09800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASKIR_RS09805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASKIR_RS09810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASKIR_RS09815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASKIR_RS09850	COG0670	Belongs to the BI1 family
ASKIR_RS09855	COG0352	thiamine-phosphate diphosphorylase activity
ASKIR_RS09865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASKIR_RS09870	COG0233	cytoplasmic translational termination
ASKIR_RS09875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASKIR_RS09895	COG3022	response to hydroperoxide
ASKIR_RS09915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ASKIR_RS09920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASKIR_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
ASKIR_RS09940	COG0783	Belongs to the Dps family
ASKIR_RS09945	COG2814	Major facilitator Superfamily
ASKIR_RS09950	COG4191	Histidine kinase
ASKIR_RS09950	COG0784	Response regulator, receiver
ASKIR_RS09965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASKIR_RS09970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASKIR_RS09985	COG0840	transmembrane signaling receptor activity
ASKIR_RS09990	COG2081	HI0933 family
ASKIR_RS10005	COG1959	2 iron, 2 sulfur cluster binding
ASKIR_RS10030	COG0175	sulfate reduction
ASKIR_RS10035	COG2895	sulfate adenylyltransferase (ATP) activity
ASKIR_RS10045	COG0133	tryptophan synthase activity
ASKIR_RS10065	COG1408	metallophosphoesterase
ASKIR_RS10070	COG1999	signal sequence binding
ASKIR_RS10085	COG2703	oxygen carrier activity
ASKIR_RS10090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASKIR_RS10095	COG4208	sulfate ABC transporter
ASKIR_RS10100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASKIR_RS10110	COG3287	FIST C domain
ASKIR_RS10110	COG2199	diguanylate cyclase activity
ASKIR_RS10110	COG2200	EAL domain
ASKIR_RS10125	COG0071	Belongs to the small heat shock protein (HSP20) family
ASKIR_RS10135	COG1217	gtp-binding protein TYPA
ASKIR_RS10140	COG2391	methyltransferase activity
ASKIR_RS10145	COG0425	Belongs to the sulfur carrier protein TusA family
ASKIR_RS10175	COG0745	RESPONSE REGULATOR receiver
ASKIR_RS10180	COG0642	Histidine kinase
ASKIR_RS10185	COG1368	sulfuric ester hydrolase activity
ASKIR_RS10190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ASKIR_RS10195	COG2860	membrane
ASKIR_RS10210	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASKIR_RS10220	COG2022	thiamine diphosphate biosynthetic process
ASKIR_RS10350	COG0840	transmembrane signaling receptor activity