locus-tag	class	description
ATH_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATH_RS00010	COG0592	DNA-directed DNA polymerase activity
ATH_RS00015	COG0187	DNA topoisomerase II activity
ATH_RS00025	COG1238	metal cluster binding
ATH_RS00035	COG0500	methyltransferase
ATH_RS00055	COG4772	TonB-dependent receptor
ATH_RS00060	COG1120	ATPase activity
ATH_RS00065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATH_RS00070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATH_RS00085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ATH_RS00120	COG0564	pseudouridine synthase activity
ATH_RS00125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATH_RS00130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATH_RS00135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATH_RS00150	COG0604	alcohol dehydrogenase
ATH_RS00155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ATH_RS00160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATH_RS00170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATH_RS00170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATH_RS00175	COG0511	ligase activity, forming carbon-carbon bonds
ATH_RS00180	COG0439	Biotin carboxylase
ATH_RS00185	COG0513	Belongs to the DEAD box helicase family
ATH_RS00190	COG0306	phosphate transporter
ATH_RS00200	COG0367	asparagine synthase
ATH_RS00210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATH_RS00215	COG1981	membrane
ATH_RS00220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATH_RS00220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATH_RS00225	COG1187	pseudouridine synthase activity
ATH_RS00230	COG0517	IMP dehydrogenase activity
ATH_RS00230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ATH_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATH_RS00245	COG0107	imidazoleglycerol-phosphate synthase activity
ATH_RS00260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ATH_RS00265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATH_RS00270	COG0724	RNA recognition motif
ATH_RS00275	COG0745	RESPONSE REGULATOR receiver
ATH_RS00280	COG0642	Histidine kinase
ATH_RS00310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATH_RS00320	COG2353	YceI-like domain
ATH_RS00330	COG1335	isochorismatase
ATH_RS00335	COG0460	homoserine dehydrogenase
ATH_RS00340	COG0436	Aminotransferase
ATH_RS00350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATH_RS00355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ATH_RS00360	COG0254	rRNA binding
ATH_RS00365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATH_RS00375	COG0109	protoheme IX farnesyltransferase activity
ATH_RS00385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ATH_RS00390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ATH_RS00395	COG0573	inorganic phosphate transmembrane transporter activity
ATH_RS00400	COG0581	inorganic phosphate transmembrane transporter activity
ATH_RS00405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATH_RS00420	COG0745	RESPONSE REGULATOR receiver
ATH_RS00425	COG0642	Histidine kinase
ATH_RS00430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ATH_RS00435	COG0315	cyclic pyranopterin monophosphate synthase activity
ATH_RS00450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ATH_RS00455	COG0587	DNA-directed DNA polymerase activity
ATH_RS00475	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ATH_RS00475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATH_RS00480	COG0504	CTP synthase activity
ATH_RS00485	COG0348	domain, Protein
ATH_RS00495	COG0237	dephospho-CoA kinase activity
ATH_RS00500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ATH_RS00505	COG3852	Histidine kinase
ATH_RS00510	COG0745	RESPONSE REGULATOR receiver
ATH_RS00515	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATH_RS00540	COG2353	YceI-like domain
ATH_RS00545	COG1846	Transcriptional regulator
ATH_RS00550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ATH_RS00555	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ATH_RS00560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATH_RS00570	COG0505	Belongs to the CarA family
ATH_RS00575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ATH_RS00585	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATH_RS00585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATH_RS00595	COG0489	protein tyrosine kinase activity
ATH_RS00605	COG1917	Cupin 2, conserved barrel domain protein
ATH_RS00610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ATH_RS00615	COG0456	acetyltransferase
ATH_RS00630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ATH_RS00630	COG0140	phosphoribosyl-ATP diphosphatase activity
ATH_RS00655	COG1410	methionine synthase
ATH_RS00655	COG0646	methionine synthase
ATH_RS00675	COG1854	S-ribosylhomocysteine lyase activity
ATH_RS00700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ATH_RS00725	COG0546	phosphoglycolate phosphatase activity
ATH_RS00740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ATH_RS00750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ATH_RS00760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATH_RS00765	COG0352	thiamine-phosphate diphosphorylase activity
ATH_RS00770	COG0352	thiamine-phosphate diphosphorylase activity
ATH_RS00770	COG0351	phosphomethylpyrimidine kinase
ATH_RS00775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATH_RS00780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATH_RS00785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATH_RS00790	COG0268	Binds directly to 16S ribosomal RNA
ATH_RS00795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATH_RS00800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATH_RS00805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATH_RS00810	COG0746	molybdenum cofactor guanylyltransferase activity
ATH_RS00830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATH_RS00835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ATH_RS00845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATH_RS00880	COG0575	Belongs to the CDS family
ATH_RS00885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATH_RS00900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATH_RS00965	COG0511	ligase activity, forming carbon-carbon bonds
ATH_RS00975	COG0840	transmembrane signaling receptor activity
ATH_RS00980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ATH_RS00985	COG1380	Effector of murein hydrolase LrgA
ATH_RS01005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATH_RS01010	COG0640	Transcriptional regulator
ATH_RS01015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ATH_RS01020	COG2059	Chromate
ATH_RS01030	COG0347	Belongs to the P(II) protein family
ATH_RS01040	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATH_RS01045	COG1706	bacterial-type flagellum-dependent cell motility
ATH_RS01055	COG1987	bacterial-type flagellum assembly
ATH_RS01080	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ATH_RS01110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATH_RS01120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATH_RS01125	COG0601	transmembrane transport
ATH_RS01130	COG0736	holo-[acyl-carrier-protein] synthase activity
ATH_RS01140	COG0786	glutamate:sodium symporter activity
ATH_RS01145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATH_RS01150	COG0646	methionine synthase
ATH_RS01150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATH_RS01155	COG0560	Phosphoserine phosphatase
ATH_RS01165	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATH_RS01170	COG1393	Belongs to the ArsC family
ATH_RS01175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATH_RS01180	COG0343	queuine tRNA-ribosyltransferase activity
ATH_RS01205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATH_RS01210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATH_RS01215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATH_RS01220	COG3278	Belongs to the heme-copper respiratory oxidase family
ATH_RS01235	COG2010	Cytochrome c
ATH_RS01260	COG0671	phosphoesterase, PA-phosphatase related
ATH_RS01280	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATH_RS01295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ATH_RS01305	COG0157	Belongs to the NadC ModD family
ATH_RS01320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ATH_RS01330	COG0083	homoserine kinase activity
ATH_RS01340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ATH_RS01345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATH_RS01350	COG0779	Required for maturation of 30S ribosomal subunits
ATH_RS01355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATH_RS01355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ATH_RS01360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATH_RS01365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATH_RS01370	COG0539	negative regulation of cytoplasmic translation
ATH_RS01370	COG1185	polyribonucleotide nucleotidyltransferase activity
ATH_RS01375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATH_RS01380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATH_RS01385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATH_RS01385	COG0072	phenylalanine-tRNA ligase activity
ATH_RS01390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATH_RS01395	COG0537	adenosine 5'-monophosphoramidase activity
ATH_RS01405	COG0825	malonyl-CoA metabolic process
ATH_RS01410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATH_RS01415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATH_RS01435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ATH_RS01445	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ATH_RS01450	COG0723	plastoquinol--plastocyanin reductase activity
ATH_RS01455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATH_RS01460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ATH_RS01465	COG0210	DNA helicase
ATH_RS01470	COG0356	it plays a direct role in the translocation of protons across the membrane
ATH_RS01475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATH_RS01480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ATH_RS01490	COG0336	Belongs to the RNA methyltransferase TrmD family
ATH_RS01495	COG0335	large ribosomal subunit rRNA binding
ATH_RS01500	COG0586	Pfam SNARE associated Golgi protein
ATH_RS01510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATH_RS01520	COG0251	oxidation-reduction process
ATH_RS01540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATH_RS01560	COG4774	siderophore transport
ATH_RS01570	COG3842	ATPase activity
ATH_RS01580	COG1840	ABC-type Fe3 transport system, periplasmic component
ATH_RS01585	COG0512	Glutamine amidotransferase of anthranilate synthase
ATH_RS01600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATH_RS01605	COG1116	anion transmembrane transporter activity
ATH_RS01620	COG4771	TonB-dependent receptor
ATH_RS01635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATH_RS01640	COG0049	tRNA binding
ATH_RS01645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATH_RS01650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATH_RS01655	COG0497	DNA recombination
ATH_RS01660	COG0840	transmembrane signaling receptor activity
ATH_RS01665	COG0826	peptidase U32
ATH_RS01675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ATH_RS01685	COG0752	glycyl-tRNA synthetase alpha subunit
ATH_RS01690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ATH_RS01700	COG1519	Transferase
ATH_RS01700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ATH_RS01705	COG0564	pseudouridine synthase activity
ATH_RS01710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATH_RS01715	COG0228	four-way junction DNA binding
ATH_RS01725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATH_RS01745	COG0745	RESPONSE REGULATOR receiver
ATH_RS01755	COG4786	Flagellar basal body rod
ATH_RS01760	COG1815	bacterial-type flagellum-dependent cell motility
ATH_RS01765	COG1766	The M ring may be actively involved in energy transduction
ATH_RS01770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATH_RS01780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATH_RS01790	COG1749	Flagellar hook protein flgE
ATH_RS01820	COG3951	Flagellar rod assembly protein muramidase FlgJ
ATH_RS01835	COG1419	protein localization to endoplasmic reticulum
ATH_RS01840	COG0455	bacterial-type flagellum organization
ATH_RS01850	COG1677	Flagellar hook-basal body complex protein FliE
ATH_RS01870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATH_RS01880	COG1157	protein secretion by the type III secretion system
ATH_RS01890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATH_RS01900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ATH_RS01905	COG0482	sulfurtransferase activity
ATH_RS01910	COG0482	sulfurtransferase activity
ATH_RS01915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATH_RS01920	COG0006	proline dipeptidase activity
ATH_RS01925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATH_RS01930	COG0402	S-adenosylhomocysteine deaminase activity
ATH_RS01935	COG0616	signal peptide processing
ATH_RS01940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATH_RS01945	COG0280	phosphate acetyltransferase
ATH_RS01950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATH_RS01955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ATH_RS01965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATH_RS01975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATH_RS01995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATH_RS02055	COG0579	oxidoreductase
ATH_RS02060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATH_RS02075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATH_RS02080	COG0840	transmembrane signaling receptor activity
ATH_RS02085	COG0840	transmembrane signaling receptor activity
ATH_RS02090	COG0052	Belongs to the universal ribosomal protein uS2 family
ATH_RS02095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATH_RS02100	COG1136	(ABC) transporter
ATH_RS02110	COG0194	GDP metabolic process
ATH_RS02115	COG4753	response regulator
ATH_RS02115	COG2207	Transcriptional regulator
ATH_RS02120	COG2217	Heavy metal translocating P-type atpase
ATH_RS02140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ATH_RS02155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATH_RS02160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATH_RS02165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ATH_RS02170	COG0352	thiamine-phosphate diphosphorylase activity
ATH_RS02175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ATH_RS02185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATH_RS02190	COG2264	protein methyltransferase activity
ATH_RS02195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATH_RS02200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATH_RS02220	COG1648	precorrin-2 dehydrogenase activity
ATH_RS02220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATH_RS02235	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATH_RS02240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ATH_RS02255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATH_RS02290	COG0481	GTPase activity
ATH_RS02300	COG2217	Heavy metal translocating P-type atpase
ATH_RS02305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATH_RS02330	COG2030	dehydratase
ATH_RS02345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ATH_RS02350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ATH_RS02355	COG0542	response to heat
ATH_RS02395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ATH_RS02405	COG0772	Belongs to the SEDS family
ATH_RS02470	COG1968	undecaprenyl-diphosphatase activity
ATH_RS02475	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ATH_RS02485	COG0314	molybdopterin synthase activity
ATH_RS02495	COG0174	glutamine synthetase
ATH_RS02520	COG0525	valine-tRNA ligase activity
ATH_RS02525	COG2814	Major facilitator Superfamily
ATH_RS02530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATH_RS02550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ATH_RS02555	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATH_RS02560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ATH_RS02570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATH_RS02575	COG1136	(ABC) transporter
ATH_RS02575	COG0577	efflux transmembrane transporter activity
ATH_RS02580	COG1136	(ABC) transporter
ATH_RS02580	COG0577	efflux transmembrane transporter activity
ATH_RS02595	COG0811	peptide transport
ATH_RS02600	COG0848	biopolymer transport protein
ATH_RS02605	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ATH_RS02615	COG0439	Biotin carboxylase
ATH_RS02620	COG4773	Receptor
ATH_RS02630	COG3041	Addiction module toxin RelE StbE family
ATH_RS02640	COG0542	response to heat
ATH_RS02645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ATH_RS02655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATH_RS02660	COG0706	membrane insertase activity
ATH_RS02670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ATH_RS02685	COG0501	Belongs to the peptidase M48B family
ATH_RS02695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ATH_RS02700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ATH_RS02705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATH_RS02715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATH_RS02720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATH_RS02730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATH_RS02735	COG0305	Participates in initiation and elongation during chromosome replication
ATH_RS02745	COG4771	TonB-dependent receptor
ATH_RS02750	COG4771	TonB-dependent receptor
ATH_RS02755	COG0500	methyltransferase
ATH_RS02775	COG1966	Carbon starvation protein
ATH_RS02780	COG0012	GTP binding
ATH_RS02800	COG3123	guanosine phosphorylase activity
ATH_RS02805	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ATH_RS02810	COG0585	pseudouridine synthase activity
ATH_RS02820	COG0840	transmembrane signaling receptor activity
ATH_RS02825	COG0632	four-way junction helicase activity
ATH_RS02830	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATH_RS02840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATH_RS02880	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ATH_RS02885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATH_RS02885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATH_RS02905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ATH_RS02925	COG1045	serine acetyltransferase
ATH_RS02930	COG1166	arginine decarboxylase activity
ATH_RS02935	COG0124	histidyl-tRNA synthetase
ATH_RS02940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATH_RS02955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATH_RS02960	COG0163	prenyltransferase activity
ATH_RS02970	COG0359	binds to the 23S rRNA
ATH_RS02975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ATH_RS02980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ATH_RS02990	COG0084	hydrolase, TatD family'
ATH_RS02995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ATH_RS03000	COG0131	Imidazoleglycerol-phosphate dehydratase
ATH_RS03005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ATH_RS03020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATH_RS03025	COG0456	acetyltransferase
ATH_RS03035	COG0051	transcription antitermination factor activity, RNA binding
ATH_RS03040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATH_RS03045	COG0088	Forms part of the polypeptide exit tunnel
ATH_RS03050	COG0089	rRNA binding
ATH_RS03055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATH_RS03060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATH_RS03065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATH_RS03070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATH_RS03075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATH_RS03080	COG0255	Belongs to the universal ribosomal protein uL29 family
ATH_RS03085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATH_RS03090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATH_RS03095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATH_RS03100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATH_RS03105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ATH_RS03110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATH_RS03115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATH_RS03120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATH_RS03125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATH_RS03130	COG0200	Binds to the 23S rRNA
ATH_RS03135	COG0201	protein transport
ATH_RS03140	COG0024	Methionine aminopeptidase
ATH_RS03145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ATH_RS03160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ATH_RS03165	COG1032	radical SAM domain protein
ATH_RS03175	COG0563	adenylate kinase activity
ATH_RS03200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATH_RS03210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATH_RS03215	COG0322	excinuclease ABC activity
ATH_RS03220	COG0840	transmembrane signaling receptor activity
ATH_RS03225	COG0753	catalase activity
ATH_RS03245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ATH_RS03255	COG0784	Response regulator, receiver
ATH_RS03255	COG3437	response regulator, receiver
ATH_RS03260	COG1338	Plays a role in the flagellum-specific transport system
ATH_RS03265	COG0768	penicillin binding
ATH_RS03285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATH_RS03290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ATH_RS03300	COG0564	pseudouridine synthase activity
ATH_RS03305	COG0772	Belongs to the SEDS family
ATH_RS03320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ATH_RS03330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ATH_RS03335	COG3123	guanosine phosphorylase activity
ATH_RS03350	COG0840	transmembrane signaling receptor activity
ATH_RS03355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATH_RS03360	COG0066	3-isopropylmalate dehydratase activity
ATH_RS03365	COG0473	3-isopropylmalate dehydrogenase activity
ATH_RS03380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ATH_RS03385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATH_RS03390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATH_RS03395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATH_RS03400	COG0202	RNA polymerase activity
ATH_RS03405	COG0203	ribosomal protein L17
ATH_RS03410	COG0154	amidase activity
ATH_RS03415	COG0516	GMP reductase activity
ATH_RS03415	COG0517	IMP dehydrogenase activity
ATH_RS03420	COG0840	transmembrane signaling receptor activity
ATH_RS03435	COG0484	heat shock protein binding
ATH_RS03450	COG0640	Transcriptional regulator
ATH_RS03455	COG2217	Heavy metal translocating P-type atpase
ATH_RS03460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATH_RS03470	COG1696	Membrane protein involved in D-alanine export
ATH_RS03490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATH_RS03495	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATH_RS03500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ATH_RS03505	COG0095	Lipoate-protein ligase
ATH_RS03510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ATH_RS03515	COG1944	ATP diphosphatase activity
ATH_RS03520	COG2258	MOSC domain
ATH_RS03525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATH_RS03530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATH_RS03535	COG3576	pyridoxamine 5-phosphate
ATH_RS03540	COG3135	benzoate transporter
ATH_RS03560	COG2169	Transcriptional regulator
ATH_RS03560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATH_RS03565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATH_RS03595	COG2166	iron-sulfur cluster assembly
ATH_RS03600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATH_RS03610	COG0396	ATPase activity
ATH_RS03615	COG0719	Fe-S assembly protein
ATH_RS03620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ATH_RS03620	COG0822	iron-sulfur transferase activity
ATH_RS03620	COG2906	2 iron, 2 sulfur cluster binding
ATH_RS03635	COG0165	Argininosuccinate lyase
ATH_RS03640	COG0784	Response regulator, receiver
ATH_RS03640	COG0835	chemotaxis
ATH_RS03645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ATH_RS03650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATH_RS03660	COG0556	nucleotide-excision repair
ATH_RS03665	COG0784	Response regulator, receiver
ATH_RS03665	COG3437	response regulator, receiver
ATH_RS03670	COG3706	GGDEF domain
ATH_RS03670	COG5001	Diguanylate cyclase
ATH_RS03670	COG2203	Gaf domain
ATH_RS03670	COG4251	negative regulation of phosphorylation
ATH_RS03675	COG0784	Response regulator, receiver
ATH_RS03675	COG2205	protein histidine kinase activity
ATH_RS03680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATH_RS03695	COG0698	ribose 5-phosphate isomerase
ATH_RS03700	COG0681	Belongs to the peptidase S26 family
ATH_RS03705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATH_RS03710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ATH_RS03715	COG0193	aminoacyl-tRNA hydrolase activity
ATH_RS03730	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATH_RS03740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATH_RS03745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATH_RS03750	COG1758	RNA polymerase activity
ATH_RS03755	COG0528	UMP kinase activity
ATH_RS03795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATH_RS03810	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ATH_RS03825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATH_RS03830	COG0840	transmembrane signaling receptor activity
ATH_RS03835	COG0840	transmembrane signaling receptor activity
ATH_RS03870	COG1793	dna ligase
ATH_RS03875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATH_RS03880	COG0133	tryptophan synthase activity
ATH_RS03890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATH_RS03895	COG0583	DNA-binding transcription factor activity
ATH_RS03900	COG1942	4-Oxalocrotonate Tautomerase
ATH_RS03910	COG0739	heme binding
ATH_RS03920	COG0488	(ABC) transporter
ATH_RS03930	COG0745	RESPONSE REGULATOR receiver
ATH_RS03945	COG3210	domain, Protein
ATH_RS03970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATH_RS03975	COG0328	RNA-DNA hybrid ribonuclease activity
ATH_RS03990	COG1132	(ABC) transporter
ATH_RS04000	COG0596	Alpha beta hydrolase
ATH_RS04035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATH_RS04035	COG0519	Catalyzes the synthesis of GMP from XMP
ATH_RS04040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ATH_RS04050	COG1451	nucleotide metabolic process
ATH_RS04055	COG0436	Aminotransferase
ATH_RS04065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATH_RS04070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATH_RS04070	COG0475	glutathione-regulated potassium exporter activity
ATH_RS04080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ATH_RS04095	COG0709	Synthesizes selenophosphate from selenide and ATP
ATH_RS04100	COG1305	Transglutaminase-like
ATH_RS04125	COG4774	siderophore transport
ATH_RS04140	COG2204	response regulator
ATH_RS04175	COG0437	4 iron, 4 sulfur cluster binding
ATH_RS04185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ATH_RS04195	COG0303	'Molybdopterin
ATH_RS04210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ATH_RS04215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ATH_RS04225	COG2204	response regulator
ATH_RS04230	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATH_RS04325	COG0582	viral genome integration into host DNA
ATH_RS04330	COG0824	Thioesterase
ATH_RS04340	COG0501	Belongs to the peptidase M48B family
ATH_RS04360	COG0037	tRNA processing
ATH_RS04370	COG0243	molybdopterin cofactor binding
ATH_RS04380	COG0745	RESPONSE REGULATOR receiver
ATH_RS04415	COG0248	Ppx GppA phosphatase
ATH_RS04425	COG0028	Belongs to the TPP enzyme family
ATH_RS04430	COG0440	acetolactate synthase activity
ATH_RS04435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATH_RS04440	COG1196	nuclear chromosome segregation
ATH_RS04440	COG1674	ftsk spoiiie
ATH_RS04475	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATH_RS04485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATH_RS04490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATH_RS04500	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATH_RS04505	COG1119	ATPase activity
ATH_RS04510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATH_RS04525	COG1090	epimerase
ATH_RS04530	COG0415	Belongs to the DNA photolyase family
ATH_RS04535	COG1193	negative regulation of DNA recombination
ATH_RS04540	COG1253	flavin adenine dinucleotide binding
ATH_RS04550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATH_RS04555	COG0135	phosphoribosylanthranilate isomerase activity
ATH_RS04560	COG2176	DNA-directed DNA polymerase activity
ATH_RS04565	COG1333	cytochrome c biogenesis protein
ATH_RS04565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATH_RS04570	COG2195	Cleaves the N-terminal amino acid of tripeptides
ATH_RS04575	COG0500	methyltransferase
ATH_RS04580	COG5001	Diguanylate cyclase
ATH_RS04585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATH_RS04590	COG2833	Protein of unknown function (DUF455)
ATH_RS04600	COG0484	heat shock protein binding
ATH_RS04605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ATH_RS04630	COG0667	Aldo Keto reductase
ATH_RS04665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ATH_RS04670	COG0511	ligase activity, forming carbon-carbon bonds
ATH_RS04670	COG5016	pyruvate
ATH_RS04690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATH_RS04690	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATH_RS04700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ATH_RS04725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATH_RS04730	COG0612	Peptidase, M16
ATH_RS04735	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ATH_RS04740	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATH_RS04745	COG0287	Prephenate dehydrogenase
ATH_RS04750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATH_RS04765	COG0527	aspartate kinase activity
ATH_RS04770	COG0494	nUDIX hydrolase
ATH_RS04775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATH_RS04780	COG2890	protein-(glutamine-N5) methyltransferase activity
ATH_RS04785	COG0339	signal peptide processing
ATH_RS04800	COG0582	viral genome integration into host DNA
ATH_RS04810	COG2201	protein-glutamate methylesterase activity
ATH_RS04815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ATH_RS04825	COG2198	Histidine kinase
ATH_RS04825	COG0643	Histidine kinase
ATH_RS04835	COG1185	polyribonucleotide nucleotidyltransferase activity
ATH_RS04845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ATH_RS04865	COG1160	GTP binding
ATH_RS04875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATH_RS04885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATH_RS04890	COG4771	TonB-dependent receptor
ATH_RS04905	COG1187	pseudouridine synthase activity
ATH_RS04910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ATH_RS04930	COG0330	HflC and HflK could
ATH_RS04940	COG5002	protein histidine kinase activity
ATH_RS04945	COG0745	RESPONSE REGULATOR receiver
ATH_RS04955	COG1283	sodium-dependent phosphate transmembrane transporter activity
ATH_RS04965	COG1114	Component of the transport system for branched-chain amino acids
ATH_RS04970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ATH_RS04975	COG0788	formyltetrahydrofolate deformylase activity
ATH_RS04980	COG0280	phosphate acetyltransferase
ATH_RS04980	COG0281	malic enzyme
ATH_RS04985	COG1496	oxidoreductase activity
ATH_RS04990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ATH_RS04995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATH_RS05005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ATH_RS05010	COG0805	protein transport
ATH_RS05035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATH_RS05040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ATH_RS05045	COG1663	tetraacyldisaccharide 4'-kinase activity
ATH_RS05050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ATH_RS05060	COG2181	nitrate reductase activity
ATH_RS05060	COG0247	lactate metabolic process
ATH_RS05065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATH_RS05080	COG0840	transmembrane signaling receptor activity
ATH_RS05095	COG1666	GTP binding
ATH_RS05100	COG2363	Small membrane protein
ATH_RS05105	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ATH_RS05120	COG1328	CTP reductase activity
ATH_RS05120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ATH_RS05125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATH_RS05130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATH_RS05150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ATH_RS05160	COG2337	Toxic component of a toxin-antitoxin (TA) module
ATH_RS05170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ATH_RS05195	COG3475	LICD family
ATH_RS05265	COG0357	Ribosomal RNA small subunit methyltransferase G
ATH_RS05270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATH_RS05275	COG0113	porphobilinogen synthase activity
ATH_RS05285	COG0745	RESPONSE REGULATOR receiver
ATH_RS05290	COG1049	propionate catabolic process, 2-methylcitrate cycle
ATH_RS05295	COG0217	transcriptional regulatory protein
ATH_RS05300	COG0739	heme binding
ATH_RS05310	COG1611	Belongs to the LOG family
ATH_RS05320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATH_RS05335	COG0300	oxidoreductase activity
ATH_RS05340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATH_RS05345	COG0742	ribosomal rna small subunit methyltransferase
ATH_RS05350	COG1418	mRNA catabolic process
ATH_RS05360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATH_RS05365	COG0552	protein localization to endoplasmic reticulum
ATH_RS05375	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ATH_RS05380	COG0861	Integral membrane protein TerC family
ATH_RS05385	COG0134	indole-3-glycerol-phosphate synthase activity
ATH_RS05395	COG0727	PFAM Uncharacterised protein family (UPF0153)
ATH_RS05400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ATH_RS05410	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATH_RS05410	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATH_RS05415	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATH_RS05435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ATH_RS05440	COG0653	protein targeting
ATH_RS05445	COG4591	ABC-type transport system involved in lipoprotein release permease component
ATH_RS05465	COG0039	L-malate dehydrogenase activity
ATH_RS05490	COG0275	rRNA processing
ATH_RS05500	COG0776	regulation of translation
ATH_RS05510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATH_RS05550	COG0166	Belongs to the GPI family
ATH_RS05570	COG0708	Exodeoxyribonuclease III
ATH_RS05580	COG2183	response to ionizing radiation
ATH_RS05595	COG0137	argininosuccinate synthase activity
ATH_RS05600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ATH_RS05605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATH_RS05615	COG1137	ATPase activity
ATH_RS05690	COG0488	(ABC) transporter
ATH_RS05695	COG2171	N-acyltransferase activity
ATH_RS05700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATH_RS05725	COG2081	HI0933 family
ATH_RS05830	COG2814	Major facilitator Superfamily
ATH_RS05840	COG0301	tRNA thio-modification
ATH_RS05840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATH_RS05860	COG1739	Uncharacterized protein family UPF0029
ATH_RS05870	COG0196	riboflavin kinase activity
ATH_RS05875	COG2226	methyltransferase
ATH_RS05880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ATH_RS05890	COG0277	FAD linked oxidase domain protein
ATH_RS05895	COG1295	ribonuclease BN
ATH_RS05905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATH_RS05915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ATH_RS05920	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ATH_RS05935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ATH_RS05940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATH_RS05945	COG0284	orotidine-5'-phosphate decarboxylase activity
ATH_RS06010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATH_RS06110	COG0776	regulation of translation
ATH_RS06120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ATH_RS06210	COG3041	Addiction module toxin RelE StbE family
ATH_RS06220	COG4974	Belongs to the 'phage' integrase family
ATH_RS06235	COG0582	viral genome integration into host DNA
ATH_RS06240	COG1278	Cold shock
ATH_RS06285	COG4895	conserved protein (DUF2196)
ATH_RS06300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ATH_RS06310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATH_RS06320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATH_RS06330	COG2391	methyltransferase activity
ATH_RS06335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATH_RS06340	COG0849	cell division
ATH_RS06350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ATH_RS06365	COG0513	Belongs to the DEAD box helicase family
ATH_RS06375	COG0754	glutathionylspermidine amidase activity
ATH_RS06380	COG1607	acyl-coa hydrolase
ATH_RS06385	COG0488	(ABC) transporter
ATH_RS06395	COG0778	Nitroreductase
ATH_RS06425	COG2855	membrane
ATH_RS06430	COG0583	DNA-binding transcription factor activity
ATH_RS06435	COG2226	methyltransferase
ATH_RS06440	COG2207	Transcriptional regulator
ATH_RS06490	COG0582	viral genome integration into host DNA
ATH_RS06495	COG2076	Multidrug Resistance protein
ATH_RS06500	COG0642	Histidine kinase
ATH_RS06505	COG0745	RESPONSE REGULATOR receiver
ATH_RS06515	COG3258	Cytochrome c
ATH_RS06525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ATH_RS06525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATH_RS06530	COG0484	heat shock protein binding
ATH_RS06535	COG0789	Transcriptional regulator
ATH_RS06540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATH_RS06555	COG0728	peptidoglycan biosynthetic process
ATH_RS06560	COG1132	(ABC) transporter
ATH_RS06565	COG0167	dihydroorotate dehydrogenase activity
ATH_RS06570	COG0612	Peptidase, M16
ATH_RS06575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATH_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
ATH_RS06585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATH_RS06590	COG0750	zinc metalloprotease
ATH_RS06595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATH_RS06600	COG0840	transmembrane signaling receptor activity
ATH_RS06605	COG0840	transmembrane signaling receptor activity
ATH_RS06615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATH_RS06625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATH_RS06640	COG0716	FMN binding
ATH_RS06650	COG1918	ferrous iron import across plasma membrane
ATH_RS06655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ATH_RS06665	COG0159	tryptophan synthase activity
ATH_RS06670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ATH_RS06675	COG2255	four-way junction helicase activity
ATH_RS06680	COG0628	permease
ATH_RS06800	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATH_RS06840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATH_RS06850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATH_RS06865	COG0598	Magnesium transport protein CorA
ATH_RS06875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATH_RS06890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATH_RS06895	COG0606	chelatase, subunit chli
ATH_RS06905	COG0242	peptide deformylase activity
ATH_RS06910	COG0740	serine-type endopeptidase activity
ATH_RS06915	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATH_RS06920	COG2326	polyphosphate kinase activity
ATH_RS06945	COG1858	cytochrome C peroxidase
ATH_RS06975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATH_RS07020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ATH_RS07030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATH_RS07045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ATH_RS07055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATH_RS07070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATH_RS07075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ATH_RS07075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ATH_RS07080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ATH_RS07085	COG1368	sulfuric ester hydrolase activity
ATH_RS07090	COG0859	PFAM glycosyl transferase family 9
ATH_RS07100	COG2194	sulfuric ester hydrolase activity
ATH_RS07105	COG0463	Glycosyl transferase, family 2
ATH_RS07130	COG3083	sulfuric ester hydrolase activity
ATH_RS07145	COG0859	PFAM glycosyl transferase family 9
ATH_RS07155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATH_RS07160	COG0483	inositol monophosphate 1-phosphatase activity
ATH_RS07190	COG3852	Histidine kinase
ATH_RS07265	COG1921	L-seryl-tRNASec selenium transferase activity
ATH_RS07315	COG2199	diguanylate cyclase activity
ATH_RS07315	COG3287	FIST C domain
ATH_RS07315	COG2200	EAL domain
ATH_RS07320	COG0259	pyridoxamine-phosphate oxidase activity
ATH_RS07330	COG0513	Belongs to the DEAD box helicase family
ATH_RS07340	COG0326	Molecular chaperone. Has ATPase activity
ATH_RS07375	COG4335	DNA alkylation repair
ATH_RS07380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATH_RS07400	COG0010	Belongs to the arginase family
ATH_RS07405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATH_RS07415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATH_RS07420	COG0668	transmembrane transport
ATH_RS07425	COG1227	inorganic diphosphatase activity
ATH_RS07450	COG1027	Aspartate ammonia-lyase
ATH_RS07455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ATH_RS07460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ATH_RS07465	COG1047	Peptidyl-prolyl cis-trans
ATH_RS07475	COG2885	chlorophyll binding
ATH_RS07480	COG0823	Involved in the tonB-independent uptake of proteins
ATH_RS07490	COG0848	biopolymer transport protein
ATH_RS07495	COG0811	peptide transport
ATH_RS07500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATH_RS07505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATH_RS07510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATH_RS07515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATH_RS07520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATH_RS07525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATH_RS07535	COG1475	DNA binding
ATH_RS07540	COG1192	Involved in chromosome partitioning
ATH_RS07545	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATH_RS07545	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATH_RS07555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATH_RS07560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATH_RS07565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATH_RS07570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATH_RS07575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATH_RS07580	COG0358	DNA primase activity
ATH_RS07590	COG0571	ribonuclease III activity
ATH_RS07595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATH_RS07600	COG2326	polyphosphate kinase activity
ATH_RS07615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATH_RS07620	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ATH_RS07630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATH_RS07635	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATH_RS07645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATH_RS07660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATH_RS07670	COG0741	lytic transglycosylase activity
ATH_RS07670	COG0739	heme binding
ATH_RS07670	COG1196	nuclear chromosome segregation
ATH_RS07690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATH_RS07695	COG0085	RNA polymerase activity
ATH_RS07700	COG0222	ribosome binding
ATH_RS07705	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATH_RS07710	COG0081	regulation of translation
ATH_RS07715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATH_RS07720	COG0250	Participates in transcription elongation, termination and antitermination
ATH_RS07735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATH_RS07740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATH_RS07770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATH_RS07775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ATH_RS07780	COG0444	Belongs to the ABC transporter superfamily
ATH_RS07785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ATH_RS07820	COG3258	Cytochrome c
ATH_RS07845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATH_RS07850	COG0475	glutathione-regulated potassium exporter activity
ATH_RS07850	COG0569	domain protein
ATH_RS07855	COG0210	DNA helicase
ATH_RS07865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ATH_RS07870	COG2996	Protein conserved in bacteria
ATH_RS07875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATH_RS07880	COG1121	(ABC) transporter
ATH_RS07885	COG0840	transmembrane signaling receptor activity
ATH_RS07890	COG1355	regulation of microtubule-based process
ATH_RS07895	COG3885	ferrous iron binding
ATH_RS07895	COG2078	PFAM AMMECR1 domain protein
ATH_RS07900	COG1648	precorrin-2 dehydrogenase activity
ATH_RS07900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATH_RS07910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATH_RS07915	COG3177	Filamentation induced by cAMP protein fic
ATH_RS07935	COG0459	protein refolding
ATH_RS07950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ATH_RS07955	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ATH_RS07965	COG0835	chemotaxis
ATH_RS07970	COG1570	exodeoxyribonuclease VII activity
ATH_RS07990	COG1692	metallophosphoesterase
ATH_RS07995	COG5002	protein histidine kinase activity
ATH_RS08015	COG2081	HI0933 family
ATH_RS08020	COG0642	Histidine kinase
ATH_RS08025	COG0745	RESPONSE REGULATOR receiver
ATH_RS08045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATH_RS08090	COG0495	leucyl-tRNA aminoacylation
ATH_RS08100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ATH_RS08105	COG1360	Flagellar Motor Protein
ATH_RS08115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATH_RS08120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATH_RS08125	COG1862	Preprotein translocase
ATH_RS08130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ATH_RS08135	COG4771	TonB-dependent receptor
ATH_RS08140	COG0617	tRNA 3'-terminal CCA addition
ATH_RS08145	COG0668	transmembrane transport
ATH_RS08150	COG0442	prolyl-tRNA aminoacylation
ATH_RS08155	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ATH_RS08160	COG0142	geranyltranstransferase activity
ATH_RS08170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ATH_RS08175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATH_RS08185	COG0811	peptide transport
ATH_RS08190	COG0848	biopolymer transport protein
ATH_RS08200	COG0628	permease
ATH_RS08210	COG0191	fructose-bisphosphate aldolase activity
ATH_RS08215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ATH_RS08220	COG0745	RESPONSE REGULATOR receiver
ATH_RS08225	COG0642	Histidine kinase
ATH_RS08235	COG2404	hydrolase activity, acting on ester bonds
ATH_RS08240	COG1959	2 iron, 2 sulfur cluster binding
ATH_RS08245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATH_RS08250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATH_RS08255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATH_RS08270	COG0243	molybdopterin cofactor binding
ATH_RS08275	COG0437	4 iron, 4 sulfur cluster binding
ATH_RS08280	COG0348	domain, Protein
ATH_RS08285	COG3043	anaerobic respiration
ATH_RS08305	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATH_RS08315	COG1971	Probably functions as a manganese efflux pump
ATH_RS08325	COG4771	TonB-dependent receptor
ATH_RS08340	COG3766	membrane
ATH_RS08350	COG0745	RESPONSE REGULATOR receiver
ATH_RS08355	COG2205	protein histidine kinase activity
ATH_RS08360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATH_RS08370	COG2824	Alkylphosphonate utilization operon protein PhnA
ATH_RS08380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATH_RS08385	COG0540	Belongs to the ATCase OTCase family
ATH_RS08395	COG1335	isochorismatase
ATH_RS08405	COG1401	restriction endodeoxyribonuclease activity
ATH_RS08405	COG1401	restriction endodeoxyribonuclease activity
ATH_RS08415	COG0181	hydroxymethylbilane synthase activity
ATH_RS08425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATH_RS08430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ATH_RS08435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATH_RS08440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ATH_RS08445	COG0450	alkyl hydroperoxide reductase
ATH_RS08455	COG0105	UTP biosynthetic process
ATH_RS08465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATH_RS08470	COG0416	fatty acid biosynthetic process
ATH_RS08475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATH_RS08495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATH_RS08500	COG1053	succinate dehydrogenase
ATH_RS08510	COG1007	ATP synthesis coupled electron transport
ATH_RS08520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATH_RS08525	COG0713	ATP synthesis coupled electron transport
ATH_RS08530	COG0839	Belongs to the complex I subunit 6 family
ATH_RS08535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATH_RS08540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ATH_RS08545	COG1034	ATP synthesis coupled electron transport
ATH_RS08550	COG0372	Belongs to the citrate synthase family
ATH_RS08560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ATH_RS08565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATH_RS08565	COG0649	NAD binding
ATH_RS08570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATH_RS08575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATH_RS08580	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ATH_RS08585	COG3610	response to peptide
ATH_RS08590	COG2966	Psort location CytoplasmicMembrane, score
ATH_RS08600	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATH_RS08605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATH_RS08615	COG0840	transmembrane signaling receptor activity
ATH_RS08620	COG3706	GGDEF domain
ATH_RS08640	COG1376	ErfK ybiS ycfS ynhG family protein
ATH_RS08645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATH_RS08655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ATH_RS08665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ATH_RS08670	COG2828	Protein conserved in bacteria
ATH_RS08675	COG0741	lytic transglycosylase activity
ATH_RS08680	COG0469	pyruvate kinase activity
ATH_RS08690	COG0792	nuclease activity
ATH_RS08695	COG0156	8-amino-7-oxononanoate synthase activity
ATH_RS08700	COG0288	reversible hydration of carbon dioxide
ATH_RS08710	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ATH_RS08720	COG2121	Domain of unknown function (DUF374)
ATH_RS08725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATH_RS08735	COG0195	Participates in both transcription termination and antitermination
ATH_RS08740	COG0215	cysteine-tRNA ligase activity
ATH_RS08750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ATH_RS08755	COG0629	single-stranded DNA binding
ATH_RS08760	COG0360	Binds together with S18 to 16S ribosomal RNA
ATH_RS08770	COG0557	exoribonuclease II activity
ATH_RS08775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ATH_RS08800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ATH_RS08805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATH_RS08810	COG0492	ferredoxin-NADP+ reductase activity
ATH_RS08815	COG3118	belongs to the thioredoxin family
ATH_RS08820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATH_RS08835	COG0642	Histidine kinase
ATH_RS08840	COG0745	RESPONSE REGULATOR receiver
ATH_RS08845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATH_RS08850	COG0129	dihydroxy-acid dehydratase activity
ATH_RS08890	COG0585	pseudouridine synthase activity
ATH_RS08905	COG0793	Belongs to the peptidase S41A family
ATH_RS08915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATH_RS08920	COG0047	phosphoribosylformylglycinamidine synthase activity
ATH_RS08930	COG0204	Acyl-transferase
ATH_RS08935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATH_RS08940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATH_RS08945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATH_RS08950	COG0018	arginyl-trna synthetase
ATH_RS08960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATH_RS08970	COG0126	phosphoglycerate kinase activity
ATH_RS08975	COG0149	triose-phosphate isomerase activity
ATH_RS08980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ATH_RS08985	COG0019	diaminopimelate decarboxylase activity
ATH_RS08990	COG1605	Chorismate mutase
ATH_RS08990	COG0077	Prephenate dehydratase
ATH_RS08995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATH_RS09000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATH_RS09010	COG0424	maF-like protein
ATH_RS09020	COG2095	MarC family integral membrane protein
ATH_RS09050	COG0189	ligase activity
ATH_RS09065	COG2199	diguanylate cyclase activity
ATH_RS09065	COG2200	EAL domain
ATH_RS09065	COG3287	FIST C domain
ATH_RS09070	COG0688	phosphatidylethanolamine metabolic process
ATH_RS09085	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ATH_RS09090	COG0443	Heat shock 70 kDa protein
ATH_RS09095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATH_RS09100	COG1420	regulation of RNA biosynthetic process
ATH_RS09120	COG0310	cobalt ion transport
ATH_RS09130	COG0375	protein maturation
ATH_RS09135	COG0309	Hydrogenase expression formation protein (HypE)
ATH_RS09145	COG1401	restriction endodeoxyribonuclease activity
ATH_RS09155	COG0409	Hydrogenase expression formation protein
ATH_RS09160	COG0298	carbon dioxide binding
ATH_RS09165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ATH_RS09175	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ATH_RS09180	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ATH_RS09185	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ATH_RS09190	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ATH_RS09195	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ATH_RS09200	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ATH_RS09205	COG0101	tRNA pseudouridine synthase activity
ATH_RS09220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATH_RS09225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ATH_RS09230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATH_RS09240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATH_RS09245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATH_RS09265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATH_RS09280	COG2089	acid synthase
ATH_RS09285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATH_RS09295	COG1083	cytidylyl-transferase
ATH_RS09300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ATH_RS09305	COG1086	Polysaccharide biosynthesis protein
ATH_RS09315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATH_RS09320	COG0733	neurotransmitter:sodium symporter activity
ATH_RS09325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ATH_RS09335	COG0659	secondary active sulfate transmembrane transporter activity
ATH_RS09345	COG1222	aaa ATPase
ATH_RS09355	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ATH_RS09380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATH_RS09385	COG0148	phosphopyruvate hydratase activity
ATH_RS09440	COG0445	tRNA wobble uridine modification
ATH_RS09450	COG2239	Acts as a magnesium transporter
ATH_RS09465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATH_RS09470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ATH_RS09475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATH_RS09485	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATH_RS09520	COG0670	Belongs to the BI1 family
ATH_RS09530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATH_RS09535	COG0233	cytoplasmic translational termination
ATH_RS09540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATH_RS09565	COG3022	response to hydroperoxide
ATH_RS09570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ATH_RS09590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ATH_RS09605	COG0546	phosphoglycolate phosphatase activity
ATH_RS09610	COG0243	molybdopterin cofactor binding
ATH_RS09620	COG0783	Belongs to the Dps family
ATH_RS09635	COG2199	diguanylate cyclase activity
ATH_RS09645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATH_RS09655	COG0840	transmembrane signaling receptor activity
ATH_RS09660	COG2081	HI0933 family
ATH_RS09670	COG1959	2 iron, 2 sulfur cluster binding
ATH_RS09685	COG0175	sulfate reduction
ATH_RS09690	COG0175	sulfate reduction
ATH_RS09695	COG2895	sulfate adenylyltransferase (ATP) activity
ATH_RS09705	COG0133	tryptophan synthase activity
ATH_RS09715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATH_RS09725	COG1408	metallophosphoesterase
ATH_RS09730	COG1999	signal sequence binding
ATH_RS09750	COG2200	EAL domain
ATH_RS09750	COG2199	diguanylate cyclase activity
ATH_RS09750	COG3287	FIST C domain
ATH_RS09760	COG1217	gtp-binding protein TYPA
ATH_RS09765	COG2391	methyltransferase activity
ATH_RS09770	COG0425	Belongs to the sulfur carrier protein TusA family
ATH_RS09780	COG0745	RESPONSE REGULATOR receiver
ATH_RS09785	COG0642	Histidine kinase
ATH_RS09790	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ATH_RS09795	COG2860	membrane
ATH_RS09825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ATH_RS09915	COG2207	Transcriptional regulator