locus-tag	class	description
ALDI51_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALDI51_RS00030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS00035	COG1024	Enoyl-CoA hydratase
ALDI51_RS00040	COG0583	DNA-binding transcription factor activity
ALDI51_RS00055	COG4770	biotin carboxylase activity
ALDI51_RS00060	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS00070	COG1254	Belongs to the acylphosphatase family
ALDI51_RS00085	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS00105	COG1609	Transcriptional regulator
ALDI51_RS00110	COG1199	ATP-dependent helicase activity
ALDI51_RS00115	COG2824	Alkylphosphonate utilization operon protein PhnA
ALDI51_RS00125	COG0791	NLP P60 protein
ALDI51_RS00130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALDI51_RS00165	COG2974	May be involved in recombination
ALDI51_RS00170	COG0700	Nucleoside recognition
ALDI51_RS00180	COG0789	Transcriptional regulator
ALDI51_RS00195	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALDI51_RS00225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALDI51_RS00250	COG2010	Cytochrome c
ALDI51_RS00255	COG0737	Belongs to the 5'-nucleotidase family
ALDI51_RS00290	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS00300	COG1902	pentaerythritol trinitrate reductase activity
ALDI51_RS00315	COG0431	NADPH-dependent FMN reductase
ALDI51_RS00320	COG0445	tRNA wobble uridine modification
ALDI51_RS00325	COG0357	Ribosomal RNA small subunit methyltransferase G
ALDI51_RS00335	COG1192	Involved in chromosome partitioning
ALDI51_RS00345	COG1475	DNA binding
ALDI51_RS00370	COG0668	transmembrane transport
ALDI51_RS00375	COG0277	FAD linked oxidase domain protein
ALDI51_RS00385	COG2096	Adenosyltransferase
ALDI51_RS00390	COG2050	protein possibly involved in aromatic compounds catabolism
ALDI51_RS00415	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS00430	COG2233	PERMEase
ALDI51_RS00445	COG0583	DNA-binding transcription factor activity
ALDI51_RS00455	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00460	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00470	COG1183	phosphatidylcholine synthase activity
ALDI51_RS00475	COG4774	siderophore transport
ALDI51_RS00490	COG0850	regulation of cytokinetic process
ALDI51_RS00500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ALDI51_RS00505	COG0583	DNA-binding transcription factor activity
ALDI51_RS00510	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS00515	COG4948	Mandelate Racemase Muconate Lactonizing
ALDI51_RS00525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALDI51_RS00530	COG2267	carboxylic ester hydrolase activity
ALDI51_RS00560	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ALDI51_RS00570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALDI51_RS00580	COG3712	iron ion homeostasis
ALDI51_RS00585	COG1595	DNA-templated transcription, initiation
ALDI51_RS00610	COG1595	DNA-templated transcription, initiation
ALDI51_RS00630	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00645	COG0583	DNA-binding transcription factor activity
ALDI51_RS00660	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS00695	COG3256	nitric oxide reductase
ALDI51_RS00700	COG3604	Transcriptional regulator
ALDI51_RS00710	COG0765	amino acid transport
ALDI51_RS00715	COG0765	amino acid transport
ALDI51_RS00725	COG1126	abc transporter atp-binding protein
ALDI51_RS00730	COG0010	Belongs to the arginase family
ALDI51_RS00745	COG1760	l-serine dehydratase
ALDI51_RS00765	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS00770	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS00795	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00805	COG0183	Belongs to the thiolase family
ALDI51_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS00830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS00840	COG0183	Belongs to the thiolase family
ALDI51_RS00845	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00850	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS00855	COG2030	dehydratase
ALDI51_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS00900	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS00905	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ALDI51_RS00910	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS00915	COG2030	dehydratase
ALDI51_RS00920	COG1024	Enoyl-CoA hydratase
ALDI51_RS00925	COG0427	acetyl-CoA hydrolase
ALDI51_RS00930	COG0183	Belongs to the thiolase family
ALDI51_RS00960	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS00990	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01015	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS01025	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01030	COG1024	Enoyl-CoA hydratase
ALDI51_RS01045	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS01055	COG0583	DNA-binding transcription factor activity
ALDI51_RS01060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS01065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALDI51_RS01075	COG3204	pilus organization
ALDI51_RS01080	COG1410	methionine synthase
ALDI51_RS01080	COG0646	methionine synthase
ALDI51_RS01100	COG0183	Belongs to the thiolase family
ALDI51_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS01110	COG2030	dehydratase
ALDI51_RS01120	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALDI51_RS01165	COG0683	leucine binding
ALDI51_RS01190	COG0347	Belongs to the P(II) protein family
ALDI51_RS01195	COG0004	ammonium transporteR
ALDI51_RS01200	COG1414	Transcriptional regulator
ALDI51_RS01205	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01220	COG2030	dehydratase
ALDI51_RS01220	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS01235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS01250	COG2084	Dehydrogenase
ALDI51_RS01280	COG2267	carboxylic ester hydrolase activity
ALDI51_RS01290	COG3180	Ammonia monooxygenase
ALDI51_RS01295	COG2079	MmgE PrpD family protein
ALDI51_RS01315	COG0277	FAD linked oxidase domain protein
ALDI51_RS01325	COG0247	lactate metabolic process
ALDI51_RS01340	COG0477	Major facilitator Superfamily
ALDI51_RS01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALDI51_RS01350	COG1858	cytochrome C peroxidase
ALDI51_RS01355	COG0625	glutathione transferase activity
ALDI51_RS01370	COG0154	amidase activity
ALDI51_RS01400	COG1216	Glycosyl transferase, family 2
ALDI51_RS01420	COG0477	Major facilitator Superfamily
ALDI51_RS01425	COG2258	MOSC domain
ALDI51_RS01460	COG2205	protein histidine kinase activity
ALDI51_RS01465	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS01505	COG4774	siderophore transport
ALDI51_RS01515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ALDI51_RS01525	COG2819	hydrolase of the alpha beta superfamily
ALDI51_RS01615	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ALDI51_RS01620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALDI51_RS01640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALDI51_RS01645	COG1414	Transcriptional regulator
ALDI51_RS01665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALDI51_RS01670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS01710	COG2159	amidohydrolase
ALDI51_RS01720	COG2084	Dehydrogenase
ALDI51_RS01730	COG1414	Transcriptional regulator
ALDI51_RS01760	COG0411	ABC transporter
ALDI51_RS01780	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS01795	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS01800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS01815	COG0708	Exodeoxyribonuclease III
ALDI51_RS01820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALDI51_RS01830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALDI51_RS01835	COG0154	amidase activity
ALDI51_RS01840	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALDI51_RS01845	COG1077	Cell shape determining protein MreB Mrl
ALDI51_RS01855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ALDI51_RS01860	COG0768	penicillin binding
ALDI51_RS01870	COG0730	response to heat
ALDI51_RS01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALDI51_RS01885	COG1127	ABC transporter
ALDI51_RS01890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALDI51_RS01890	COG3008	intermembrane lipid transfer
ALDI51_RS01900	COG1309	transcriptional regulator
ALDI51_RS01905	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS01910	COG1024	Enoyl-CoA hydratase
ALDI51_RS01915	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01920	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS01940	COG0583	DNA-binding transcription factor activity
ALDI51_RS01945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALDI51_RS01955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALDI51_RS01960	COG2095	MarC family integral membrane protein
ALDI51_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS01970	COG0412	Dienelactone hydrolase
ALDI51_RS02010	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS02025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS02035	COG0598	Magnesium transport protein CorA
ALDI51_RS02050	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS02060	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS02065	COG1024	Enoyl-CoA hydratase
ALDI51_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS02080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ALDI51_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS02085	COG2030	dehydratase
ALDI51_RS02095	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS02110	COG2186	Transcriptional regulator
ALDI51_RS02120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS02135	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS02150	COG1981	membrane
ALDI51_RS02165	COG2945	thiolester hydrolase activity
ALDI51_RS02170	COG1686	Belongs to the peptidase S11 family
ALDI51_RS02175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALDI51_RS02180	COG0049	tRNA binding
ALDI51_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALDI51_RS02190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALDI51_RS02195	COG0051	transcription antitermination factor activity, RNA binding
ALDI51_RS02200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALDI51_RS02205	COG0088	Forms part of the polypeptide exit tunnel
ALDI51_RS02210	COG0089	rRNA binding
ALDI51_RS02215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALDI51_RS02220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALDI51_RS02225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALDI51_RS02230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALDI51_RS02235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALDI51_RS02240	COG0255	Belongs to the universal ribosomal protein uL29 family
ALDI51_RS02245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALDI51_RS02250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ALDI51_RS02250	COG0678	peroxiredoxin activity
ALDI51_RS02255	COG0456	acetyltransferase
ALDI51_RS02265	COG3909	cytochrome
ALDI51_RS02270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALDI51_RS02285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALDI51_RS02290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALDI51_RS02295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALDI51_RS02300	COG0321	lipoyl(octanoyl) transferase activity
ALDI51_RS02305	COG2921	Belongs to the UPF0250 family
ALDI51_RS02315	COG0356	it plays a direct role in the translocation of protons across the membrane
ALDI51_RS02325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALDI51_RS02330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALDI51_RS02335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALDI51_RS02340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALDI51_RS02345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALDI51_RS02350	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALDI51_RS02380	COG3245	cytochrome
ALDI51_RS02390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS02395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS02425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALDI51_RS02435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ALDI51_RS02445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALDI51_RS02450	COG0081	regulation of translation
ALDI51_RS02455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALDI51_RS02460	COG0222	ribosome binding
ALDI51_RS02465	COG0085	RNA polymerase activity
ALDI51_RS02470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALDI51_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALDI51_RS02480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALDI51_RS02490	COG5000	phosphorelay sensor kinase activity
ALDI51_RS02495	COG2204	response regulator
ALDI51_RS02515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS02525	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS02550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALDI51_RS02565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALDI51_RS02570	COG0792	nuclease activity
ALDI51_RS02575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ALDI51_RS02580	COG2823	Periplasmic or secreted lipoprotein
ALDI51_RS02585	COG2084	Dehydrogenase
ALDI51_RS02595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS02605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALDI51_RS02620	COG2733	membrane
ALDI51_RS02625	COG0277	FAD linked oxidase domain protein
ALDI51_RS02630	COG0583	DNA-binding transcription factor activity
ALDI51_RS02650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALDI51_RS02655	COG4585	Histidine kinase
ALDI51_RS02660	COG2197	response regulator
ALDI51_RS02670	COG2223	nitrite transmembrane transporter activity
ALDI51_RS02675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ALDI51_RS02680	COG1140	nitrate reductase beta subunit
ALDI51_RS02685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ALDI51_RS02690	COG2181	nitrate reductase activity
ALDI51_RS02700	COG0288	reversible hydration of carbon dioxide
ALDI51_RS02715	COG3945	hemerythrin HHE cation binding domain
ALDI51_RS02740	COG0243	molybdopterin cofactor binding
ALDI51_RS02750	COG1473	amidohydrolase
ALDI51_RS02765	COG2818	Glycosylase
ALDI51_RS02775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALDI51_RS02790	COG0583	DNA-binding transcription factor activity
ALDI51_RS02830	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS02840	COG1022	Amp-dependent synthetase and ligase
ALDI51_RS02845	COG3409	Peptidoglycan-binding domain 1 protein
ALDI51_RS02845	COG3267	Type II secretory pathway component ExeA
ALDI51_RS02855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS02860	COG1187	pseudouridine synthase activity
ALDI51_RS02865	COG0326	Molecular chaperone. Has ATPase activity
ALDI51_RS02895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ALDI51_RS02940	COG1203	CRISPR-associated helicase, Cas3
ALDI51_RS02970	COG1518	maintenance of DNA repeat elements
ALDI51_RS02980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS02995	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS03025	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ALDI51_RS03030	COG1131	(ABC) transporter
ALDI51_RS03035	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALDI51_RS03040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALDI51_RS03045	COG3300	MHYT domain
ALDI51_RS03045	COG5001	Diguanylate cyclase
ALDI51_RS03050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALDI51_RS03055	COG1490	D-aminoacyl-tRNA deacylase activity
ALDI51_RS03060	COG3177	Filamentation induced by cAMP protein fic
ALDI51_RS03065	COG0730	response to heat
ALDI51_RS03080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS03085	COG0604	alcohol dehydrogenase
ALDI51_RS03090	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS03095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALDI51_RS03100	COG1702	phosphate starvation-inducible protein PhoH
ALDI51_RS03105	COG0632	four-way junction helicase activity
ALDI51_RS03115	COG0443	Heat shock 70 kDa protein
ALDI51_RS03120	COG0443	Heat shock 70 kDa protein
ALDI51_RS03130	COG2255	four-way junction helicase activity
ALDI51_RS03175	COG3616	Alanine racemase, N-terminal domain
ALDI51_RS03190	COG0037	tRNA processing
ALDI51_RS03220	COG2175	clavaminate synthase activity
ALDI51_RS03235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALDI51_RS03245	COG2175	clavaminate synthase activity
ALDI51_RS03260	COG1940	carbohydrate kinase activity
ALDI51_RS03265	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ALDI51_RS03270	COG3387	PFAM Glycoside hydrolase 15-related
ALDI51_RS03275	COG1877	trehalose-phosphatase activity
ALDI51_RS03285	COG0617	tRNA 3'-terminal CCA addition
ALDI51_RS03300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALDI51_RS03305	COG1196	nuclear chromosome segregation
ALDI51_RS03305	COG0739	heme binding
ALDI51_RS03305	COG0741	lytic transglycosylase activity
ALDI51_RS03320	COG3128	pkhd-type hydroxylase
ALDI51_RS03330	COG4774	siderophore transport
ALDI51_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS03355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALDI51_RS03360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALDI51_RS03375	COG1522	sequence-specific DNA binding
ALDI51_RS03385	COG3186	Phenylalanine-4-hydroxylase
ALDI51_RS03395	COG0022	dehydrogenase e1 component
ALDI51_RS03410	COG0752	glycyl-tRNA synthetase alpha subunit
ALDI51_RS03415	COG0751	glycine-tRNA ligase activity
ALDI51_RS03420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ALDI51_RS03425	COG0204	Acyl-transferase
ALDI51_RS03440	COG1652	LysM domain
ALDI51_RS03445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALDI51_RS03485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALDI51_RS03490	COG1459	type II secretion system
ALDI51_RS03495	COG2165	general secretion pathway protein
ALDI51_RS03500	COG4970	Tfp pilus assembly protein FimT
ALDI51_RS03505	COG2165	general secretion pathway protein
ALDI51_RS03535	COG1450	Type ii and iii secretion system protein
ALDI51_RS03590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALDI51_RS03595	COG1309	transcriptional regulator
ALDI51_RS03605	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS03615	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS03615	COG1024	Enoyl-CoA hydratase
ALDI51_RS03620	COG2852	Protein conserved in bacteria
ALDI51_RS03625	COG0183	Belongs to the thiolase family
ALDI51_RS03635	COG1024	Enoyl-CoA hydratase
ALDI51_RS03650	COG5265	(ABC) transporter
ALDI51_RS03655	COG1021	2,3-dihydroxybenzoate-AMP ligase
ALDI51_RS03665	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS03675	COG0583	DNA-binding transcription factor activity
ALDI51_RS03685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALDI51_RS03690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALDI51_RS03690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALDI51_RS03695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALDI51_RS03700	COG0583	DNA-binding transcription factor activity
ALDI51_RS03705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS03710	COG0765	amino acid transport
ALDI51_RS03715	COG0765	amino acid transport
ALDI51_RS03720	COG1126	abc transporter atp-binding protein
ALDI51_RS03725	COG2423	ornithine cyclodeaminase activity
ALDI51_RS03740	COG3039	Transposase
ALDI51_RS03760	COG2076	Multidrug Resistance protein
ALDI51_RS03770	COG2755	lipolytic protein G-D-S-L family
ALDI51_RS03770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ALDI51_RS03775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ALDI51_RS03785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALDI51_RS03795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ALDI51_RS03800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALDI51_RS03805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ALDI51_RS03810	COG0515	serine threonine protein kinase
ALDI51_RS03815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALDI51_RS03820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALDI51_RS03825	COG0316	Belongs to the HesB IscA family
ALDI51_RS03830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ALDI51_RS03835	COG0739	heme binding
ALDI51_RS03840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALDI51_RS03845	COG0583	DNA-binding transcription factor activity
ALDI51_RS03850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALDI51_RS03870	COG1522	sequence-specific DNA binding
ALDI51_RS03885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALDI51_RS03890	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ALDI51_RS03895	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS03900	COG5002	protein histidine kinase activity
ALDI51_RS03930	COG0489	protein tyrosine kinase activity
ALDI51_RS03940	COG3409	Peptidoglycan-binding domain 1 protein
ALDI51_RS03940	COG3267	Type II secretory pathway component ExeA
ALDI51_RS03965	COG0367	asparagine synthase
ALDI51_RS03970	COG0438	transferase activity, transferring glycosyl groups
ALDI51_RS03975	COG0297	glycogen (starch) synthase activity
ALDI51_RS03985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALDI51_RS03990	COG0438	transferase activity, transferring glycosyl groups
ALDI51_RS04020	COG1216	Glycosyl transferase, family 2
ALDI51_RS04065	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS04075	COG3850	Histidine kinase
ALDI51_RS04075	COG5002	protein histidine kinase activity
ALDI51_RS04080	COG2204	response regulator
ALDI51_RS04095	COG2076	Multidrug Resistance protein
ALDI51_RS04100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALDI51_RS04100	COG0546	phosphoglycolate phosphatase activity
ALDI51_RS04105	COG0583	DNA-binding transcription factor activity
ALDI51_RS04110	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS04120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALDI51_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS04155	COG3045	CreA protein
ALDI51_RS04160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALDI51_RS04160	COG0189	ligase activity
ALDI51_RS04165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALDI51_RS04165	COG0189	ligase activity
ALDI51_RS04170	COG1132	(ABC) transporter
ALDI51_RS04200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALDI51_RS04270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ALDI51_RS04275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALDI51_RS04285	COG1765	OsmC-like protein
ALDI51_RS04290	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ALDI51_RS04310	COG1473	amidohydrolase
ALDI51_RS04315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALDI51_RS04320	COG0444	Belongs to the ABC transporter superfamily
ALDI51_RS04325	COG4608	Belongs to the ABC transporter superfamily
ALDI51_RS04330	COG1881	PFAM PEBP family protein
ALDI51_RS04335	COG0837	glucose binding
ALDI51_RS04335	COG1737	Transcriptional regulator
ALDI51_RS04340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALDI51_RS04345	COG0166	Belongs to the GPI family
ALDI51_RS04350	COG0459	protein refolding
ALDI51_RS04355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALDI51_RS04360	COG0583	DNA-binding transcription factor activity
ALDI51_RS04365	COG2855	membrane
ALDI51_RS04380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS04390	COG0604	alcohol dehydrogenase
ALDI51_RS04395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS04425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALDI51_RS04430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALDI51_RS04440	COG1560	Kdo2-lipid A biosynthetic process
ALDI51_RS04445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALDI51_RS04455	COG1333	cytochrome c biogenesis protein
ALDI51_RS04460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALDI51_RS04465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALDI51_RS04470	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ALDI51_RS04485	COG1965	Belongs to the frataxin family
ALDI51_RS04530	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ALDI51_RS04565	COG0070	glutamate synthase
ALDI51_RS04565	COG0069	glutamate synthase activity
ALDI51_RS04565	COG0067	glutamate synthase
ALDI51_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS04580	COG0765	amino acid transport
ALDI51_RS04585	COG1126	abc transporter atp-binding protein
ALDI51_RS04595	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS04605	COG1024	Enoyl-CoA hydratase
ALDI51_RS04610	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS04620	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS04625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS04640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALDI51_RS04645	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ALDI51_RS04650	COG1127	ABC transporter
ALDI51_RS04655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALDI51_RS04660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALDI51_RS04680	COG2199	diguanylate cyclase activity
ALDI51_RS04685	COG1131	(ABC) transporter
ALDI51_RS04690	COG0842	Transport permease protein
ALDI51_RS04695	COG5007	Belongs to the BolA IbaG family
ALDI51_RS04700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALDI51_RS04705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALDI51_RS04720	COG4804	nuclease activity
ALDI51_RS04725	COG2003	Belongs to the UPF0758 family
ALDI51_RS04735	COG4916	TIR domain
ALDI51_RS04760	COG5489	Protein of unknown function (DUF736)
ALDI51_RS04765	COG1396	sequence-specific DNA binding
ALDI51_RS04810	COG4959	Type IV secretory pathway protease TraF
ALDI51_RS04845	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ALDI51_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS04880	COG1902	pentaerythritol trinitrate reductase activity
ALDI51_RS04890	COG1335	isochorismatase
ALDI51_RS04905	COG0583	DNA-binding transcription factor activity
ALDI51_RS04925	COG4962	Type ii secretion system protein e
ALDI51_RS04930	COG3838	Conjugal transfer protein Trbc
ALDI51_RS04940	COG3451	type IV secretory pathway VirB4
ALDI51_RS04990	COG0183	Belongs to the thiolase family
ALDI51_RS04995	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS05015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALDI51_RS05020	COG0131	Imidazoleglycerol-phosphate dehydratase
ALDI51_RS05030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALDI51_RS05045	COG0438	transferase activity, transferring glycosyl groups
ALDI51_RS05075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ALDI51_RS05080	COG0107	imidazoleglycerol-phosphate synthase activity
ALDI51_RS05085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALDI51_RS05090	COG0140	phosphoribosyl-ATP diphosphatase activity
ALDI51_RS05105	COG0537	adenosine 5'-monophosphoramidase activity
ALDI51_RS05110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALDI51_RS05115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALDI51_RS05120	COG0805	protein transport
ALDI51_RS05125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALDI51_RS05130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALDI51_RS05135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALDI51_RS05140	COG1970	mechanosensitive ion channel activity
ALDI51_RS05145	COG0723	plastoquinol--plastocyanin reductase activity
ALDI51_RS05150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALDI51_RS05155	COG2857	Cytochrome c1
ALDI51_RS05160	COG0625	glutathione transferase activity
ALDI51_RS05165	COG2969	positive regulation of protein catabolic process
ALDI51_RS05180	COG0653	protein targeting
ALDI51_RS05185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALDI51_RS05195	COG0494	nUDIX hydrolase
ALDI51_RS05200	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ALDI51_RS05205	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ALDI51_RS05210	COG0237	dephospho-CoA kinase activity
ALDI51_RS05235	COG0142	geranyltranstransferase activity
ALDI51_RS05240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALDI51_RS05245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ALDI51_RS05250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALDI51_RS05255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALDI51_RS05260	COG0494	nUDIX hydrolase
ALDI51_RS05265	COG0442	prolyl-tRNA aminoacylation
ALDI51_RS05275	COG1253	flavin adenine dinucleotide binding
ALDI51_RS05280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALDI51_RS05285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ALDI51_RS05290	COG2890	protein-(glutamine-N5) methyltransferase activity
ALDI51_RS05295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALDI51_RS05300	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALDI51_RS05325	COG1511	domain protein
ALDI51_RS05325	COG3264	Mechanosensitive ion channel
ALDI51_RS05330	COG0584	glycerophosphoryl diester phosphodiesterase
ALDI51_RS05335	COG3842	ATPase activity
ALDI51_RS05340	COG0395	ABC-type sugar transport system, permease component
ALDI51_RS05345	COG1175	transmembrane transport
ALDI51_RS05350	COG1653	transport
ALDI51_RS05355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALDI51_RS05375	COG2226	methyltransferase
ALDI51_RS05390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALDI51_RS05410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALDI51_RS05425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALDI51_RS05430	COG0302	gtp cyclohydrolase
ALDI51_RS05445	COG4191	Histidine kinase
ALDI51_RS05450	COG4566	intracellular signal transduction
ALDI51_RS05455	COG3258	Cytochrome c
ALDI51_RS05470	COG1280	lysine exporter protein (LysE YggA)
ALDI51_RS05475	COG0154	amidase activity
ALDI51_RS05485	COG4608	Belongs to the ABC transporter superfamily
ALDI51_RS05490	COG0444	Belongs to the ABC transporter superfamily
ALDI51_RS05495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALDI51_RS05505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALDI51_RS05510	COG0193	aminoacyl-tRNA hydrolase activity
ALDI51_RS05515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALDI51_RS05520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALDI51_RS05530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALDI51_RS05545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ALDI51_RS05555	COG1194	a g-specific adenine glycosylase
ALDI51_RS05560	COG1660	Displays ATPase and GTPase activities
ALDI51_RS05565	COG0497	DNA recombination
ALDI51_RS05570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALDI51_RS05575	COG1420	regulation of RNA biosynthetic process
ALDI51_RS05580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALDI51_RS05585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS05595	COG0436	Aminotransferase
ALDI51_RS05600	COG0765	amino acid transport
ALDI51_RS05605	COG0765	amino acid transport
ALDI51_RS05615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS05620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS05635	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALDI51_RS05640	COG1984	allophanate hydrolase subunit 2
ALDI51_RS05645	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALDI51_RS05655	COG0439	Biotin carboxylase
ALDI51_RS05670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALDI51_RS05675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALDI51_RS05695	COG1561	YicC-like family, N-terminal region
ALDI51_RS05765	COG1222	aaa ATPase
ALDI51_RS05795	COG0194	GDP metabolic process
ALDI51_RS05800	COG1758	RNA polymerase activity
ALDI51_RS05805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALDI51_RS05825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALDI51_RS05830	COG1185	polyribonucleotide nucleotidyltransferase activity
ALDI51_RS05835	COG3321	synthase
ALDI51_RS05835	COG0604	alcohol dehydrogenase
ALDI51_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS05840	COG0149	triose-phosphate isomerase activity
ALDI51_RS05855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALDI51_RS05860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALDI51_RS05865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALDI51_RS05870	COG0649	NAD binding
ALDI51_RS05885	COG1034	ATP synthesis coupled electron transport
ALDI51_RS05890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ALDI51_RS05895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALDI51_RS05905	COG0713	ATP synthesis coupled electron transport
ALDI51_RS05920	COG1007	ATP synthesis coupled electron transport
ALDI51_RS05940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALDI51_RS05945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ALDI51_RS05955	COG0586	Pfam SNARE associated Golgi protein
ALDI51_RS05960	COG0402	S-adenosylhomocysteine deaminase activity
ALDI51_RS05965	COG2252	PERMEase
ALDI51_RS05975	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALDI51_RS05980	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ALDI51_RS05990	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALDI51_RS05995	COG0802	atpase or kinase
ALDI51_RS06000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALDI51_RS06010	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS06015	COG4974	Belongs to the 'phage' integrase family
ALDI51_RS06025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALDI51_RS06030	COG0840	transmembrane signaling receptor activity
ALDI51_RS06035	COG3300	MHYT domain
ALDI51_RS06035	COG5001	Diguanylate cyclase
ALDI51_RS06050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALDI51_RS06055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALDI51_RS06060	COG2833	Protein of unknown function (DUF455)
ALDI51_RS06070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ALDI51_RS06110	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALDI51_RS06115	COG0148	phosphopyruvate hydratase activity
ALDI51_RS06125	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALDI51_RS06130	COG0504	CTP synthase activity
ALDI51_RS06135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ALDI51_RS06145	COG0756	dUTP diphosphatase activity
ALDI51_RS06150	COG1047	Peptidyl-prolyl cis-trans
ALDI51_RS06155	COG2850	peptidyl-arginine hydroxylation
ALDI51_RS06170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ALDI51_RS06175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALDI51_RS06215	COG0583	DNA-binding transcription factor activity
ALDI51_RS06230	COG1233	COG1233 Phytoene dehydrogenase and related
ALDI51_RS06245	COG1473	amidohydrolase
ALDI51_RS06255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ALDI51_RS06260	COG2814	Major facilitator Superfamily
ALDI51_RS06280	COG1722	exodeoxyribonuclease VII activity
ALDI51_RS06290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALDI51_RS06295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALDI51_RS06300	COG1201	RNA secondary structure unwinding
ALDI51_RS06305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALDI51_RS06315	COG0483	inositol monophosphate 1-phosphatase activity
ALDI51_RS06325	COG1045	serine acetyltransferase
ALDI51_RS06335	COG1063	alcohol dehydrogenase
ALDI51_RS06340	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALDI51_RS06350	COG0312	modulator of DNA gyrase
ALDI51_RS06355	COG3179	chitinase
ALDI51_RS06365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ALDI51_RS06370	COG1104	cysteine desulfurase activity
ALDI51_RS06375	COG2814	Major facilitator Superfamily
ALDI51_RS06385	COG3385	transposase activity
ALDI51_RS06395	COG0114	fumarate hydratase activity
ALDI51_RS06405	COG4774	siderophore transport
ALDI51_RS06410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS06415	COG2113	Glycine betaine
ALDI51_RS06420	COG4176	ABC-type proline glycine betaine transport system permease component
ALDI51_RS06425	COG4175	Glycine betaine
ALDI51_RS06435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALDI51_RS06440	COG2304	oxidoreductase activity
ALDI51_RS06450	COG0714	Associated with various cellular activities
ALDI51_RS06455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALDI51_RS06465	COG0640	Transcriptional regulator
ALDI51_RS06475	COG0084	hydrolase, TatD family'
ALDI51_RS06480	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ALDI51_RS06500	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALDI51_RS06505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALDI51_RS06525	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS06540	COG0697	spore germination
ALDI51_RS06555	COG0583	DNA-binding transcription factor activity
ALDI51_RS06570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ALDI51_RS06575	COG3842	ATPase activity
ALDI51_RS06590	COG1840	ABC-type Fe3 transport system, periplasmic component
ALDI51_RS06595	COG1609	Transcriptional regulator
ALDI51_RS06600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALDI51_RS06610	COG0196	riboflavin kinase activity
ALDI51_RS06620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALDI51_RS06625	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS06630	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS06635	COG3132	Protein of unknown function, DUF480
ALDI51_RS06640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ALDI51_RS06670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALDI51_RS06670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALDI51_RS06675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALDI51_RS06680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALDI51_RS06685	COG0492	ferredoxin-NADP+ reductase activity
ALDI51_RS06690	COG1674	ftsk spoiiie
ALDI51_RS06695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALDI51_RS06700	COG1575	Belongs to the MenA family. Type 1 subfamily
ALDI51_RS06705	COG1573	uracil-dna glycosylase
ALDI51_RS06755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALDI51_RS06760	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS06790	COG1392	Phosphate transport regulator
ALDI51_RS06795	COG0306	phosphate transporter
ALDI51_RS06810	COG0228	four-way junction DNA binding
ALDI51_RS06815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALDI51_RS06820	COG0336	Belongs to the RNA methyltransferase TrmD family
ALDI51_RS06825	COG0335	large ribosomal subunit rRNA binding
ALDI51_RS06830	COG0494	nUDIX hydrolase
ALDI51_RS06835	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALDI51_RS06840	COG0659	secondary active sulfate transmembrane transporter activity
ALDI51_RS06845	COG1162	GTPase activity
ALDI51_RS06850	COG2154	pterin-4-alpha-carbinolamine dehydratase
ALDI51_RS06855	COG0501	Belongs to the peptidase M48B family
ALDI51_RS06860	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALDI51_RS06875	COG0513	Belongs to the DEAD box helicase family
ALDI51_RS06880	COG5002	protein histidine kinase activity
ALDI51_RS06880	COG5001	Diguanylate cyclase
ALDI51_RS06880	COG3447	MASE1 domain protein
ALDI51_RS06885	COG2814	Major facilitator Superfamily
ALDI51_RS06920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALDI51_RS06930	COG4771	TonB-dependent receptor
ALDI51_RS06965	COG0516	GMP reductase activity
ALDI51_RS06970	COG0210	DNA helicase
ALDI51_RS06980	COG3706	GGDEF domain
ALDI51_RS06980	COG2203	Gaf domain
ALDI51_RS06980	COG4251	negative regulation of phosphorylation
ALDI51_RS06980	COG5001	Diguanylate cyclase
ALDI51_RS06990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ALDI51_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS07030	COG0583	DNA-binding transcription factor activity
ALDI51_RS07040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS07045	COG1024	Enoyl-CoA hydratase
ALDI51_RS07050	COG0412	Dienelactone hydrolase
ALDI51_RS07065	COG0560	Phosphoserine phosphatase
ALDI51_RS07085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALDI51_RS07090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALDI51_RS07090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALDI51_RS07095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALDI51_RS07095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALDI51_RS07115	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07120	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07125	COG0583	DNA-binding transcription factor activity
ALDI51_RS07130	COG0183	Belongs to the thiolase family
ALDI51_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS07170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALDI51_RS07185	COG0724	RNA recognition motif
ALDI51_RS07190	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ALDI51_RS07195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALDI51_RS07215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALDI51_RS07245	COG1477	protein flavinylation
ALDI51_RS07250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ALDI51_RS07255	COG4771	TonB-dependent receptor
ALDI51_RS07260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ALDI51_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS07285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALDI51_RS07300	COG1122	ATPase activity
ALDI51_RS07390	COG0071	Belongs to the small heat shock protein (HSP20) family
ALDI51_RS07395	COG1136	(ABC) transporter
ALDI51_RS07400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALDI51_RS07405	COG2814	Major facilitator Superfamily
ALDI51_RS07410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS07415	COG0537	adenosine 5'-monophosphoramidase activity
ALDI51_RS07430	COG3447	MASE1 domain protein
ALDI51_RS07430	COG5001	Diguanylate cyclase
ALDI51_RS07430	COG5002	protein histidine kinase activity
ALDI51_RS07435	COG1129	ABC transporter
ALDI51_RS07440	COG4603	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS07470	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS07475	COG4221	oxidoreductase activity
ALDI51_RS07495	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07500	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALDI51_RS07510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ALDI51_RS07515	COG0727	PFAM Uncharacterised protein family (UPF0153)
ALDI51_RS07535	COG0727	PFAM Uncharacterised protein family (UPF0153)
ALDI51_RS07550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALDI51_RS07555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALDI51_RS07565	COG0268	Binds directly to 16S ribosomal RNA
ALDI51_RS07570	COG0728	peptidoglycan biosynthetic process
ALDI51_RS07580	COG0589	response to stress
ALDI51_RS07590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALDI51_RS07595	COG0405	Gamma-glutamyltransferase
ALDI51_RS07600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALDI51_RS07610	COG0617	tRNA 3'-terminal CCA addition
ALDI51_RS07615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALDI51_RS07625	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS07635	COG0583	DNA-binding transcription factor activity
ALDI51_RS07640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ALDI51_RS07665	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS07670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS07675	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07680	COG0583	DNA-binding transcription factor activity
ALDI51_RS07685	COG1346	cytolysis
ALDI51_RS07735	COG3712	iron ion homeostasis
ALDI51_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS07760	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS07765	COG2084	Dehydrogenase
ALDI51_RS07770	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS07785	COG1609	Transcriptional regulator
ALDI51_RS07790	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS07795	COG3618	amidohydrolase
ALDI51_RS07845	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS07850	COG2030	dehydratase
ALDI51_RS07850	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS07865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS07870	COG1454	alcohol dehydrogenase
ALDI51_RS07880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALDI51_RS07930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALDI51_RS07935	COG4829	muconolactone delta-isomerase
ALDI51_RS08000	COG3311	Transcriptional regulator
ALDI51_RS08005	COG0582	viral genome integration into host DNA
ALDI51_RS08020	COG0513	Belongs to the DEAD box helicase family
ALDI51_RS08025	COG0488	(ABC) transporter
ALDI51_RS08035	COG3191	aminopeptidase activity
ALDI51_RS08065	COG0789	Transcriptional regulator
ALDI51_RS08085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ALDI51_RS08090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALDI51_RS08090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALDI51_RS08110	COG0052	Belongs to the universal ribosomal protein uS2 family
ALDI51_RS08115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALDI51_RS08120	COG0528	UMP kinase activity
ALDI51_RS08125	COG0233	cytoplasmic translational termination
ALDI51_RS08130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALDI51_RS08135	COG0575	Belongs to the CDS family
ALDI51_RS08140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ALDI51_RS08145	COG0750	zinc metalloprotease
ALDI51_RS08160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALDI51_RS08165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALDI51_RS08170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALDI51_RS08175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALDI51_RS08180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALDI51_RS08185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALDI51_RS08195	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALDI51_RS08200	COG0308	aminopeptidase N
ALDI51_RS08220	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS08250	COG3842	ATPase activity
ALDI51_RS08255	COG0667	Aldo Keto reductase
ALDI51_RS08265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALDI51_RS08275	COG3577	Aspartyl protease
ALDI51_RS08280	COG1666	GTP binding
ALDI51_RS08285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALDI51_RS08295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ALDI51_RS08300	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ALDI51_RS08305	COG0145	ligase activity
ALDI51_RS08310	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ALDI51_RS08315	COG4647	ligase activity
ALDI51_RS08320	COG3284	Transcriptional regulator
ALDI51_RS08325	COG0137	argininosuccinate synthase activity
ALDI51_RS08330	COG3123	guanosine phosphorylase activity
ALDI51_RS08340	COG1393	Belongs to the ArsC family
ALDI51_RS08345	COG0285	dihydrofolate synthase activity
ALDI51_RS08355	COG1286	toxin biosynthetic process
ALDI51_RS08370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALDI51_RS08415	COG1840	ABC-type Fe3 transport system, periplasmic component
ALDI51_RS08430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALDI51_RS08440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS08455	COG1611	Belongs to the LOG family
ALDI51_RS08460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALDI51_RS08475	COG2212	antiporter activity
ALDI51_RS08485	COG0651	ATP synthesis coupled electron transport
ALDI51_RS08490	COG1006	Multisubunit Na H antiporter MnhC subunit
ALDI51_RS08495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALDI51_RS08495	COG2111	Na H antiporter
ALDI51_RS08505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ALDI51_RS08515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALDI51_RS08525	COG2917	probably involved in intracellular septation
ALDI51_RS08530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALDI51_RS08535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ALDI51_RS08540	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS08550	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS08560	COG0411	ABC transporter
ALDI51_RS08570	COG1024	Enoyl-CoA hydratase
ALDI51_RS08570	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS08575	COG0183	Belongs to the thiolase family
ALDI51_RS08580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS08585	COG0765	amino acid transport
ALDI51_RS08590	COG0765	amino acid transport
ALDI51_RS08595	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS08640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALDI51_RS08715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALDI51_RS08740	COG3328	transposase activity
ALDI51_RS08760	COG0270	DNA (cytosine-5-)-methyltransferase activity
ALDI51_RS08790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALDI51_RS08795	COG1120	ATPase activity
ALDI51_RS08800	COG4988	ABC transporter
ALDI51_RS08805	COG1132	(ABC) transporter
ALDI51_RS08825	COG1309	transcriptional regulator
ALDI51_RS08830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALDI51_RS08860	COG0259	pyridoxamine-phosphate oxidase activity
ALDI51_RS08885	COG2183	response to ionizing radiation
ALDI51_RS08905	COG3618	amidohydrolase
ALDI51_RS08940	COG4566	intracellular signal transduction
ALDI51_RS08950	COG2807	transmembrane transport
ALDI51_RS08955	COG0590	tRNA wobble adenosine to inosine editing
ALDI51_RS08960	COG0354	folic acid binding
ALDI51_RS08965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALDI51_RS08970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALDI51_RS08975	COG0470	DNA polymerase III
ALDI51_RS08985	COG0084	hydrolase, TatD family'
ALDI51_RS09005	COG1802	Transcriptional regulator
ALDI51_RS09010	COG2814	Major facilitator Superfamily
ALDI51_RS09015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALDI51_RS09020	COG4336	lyase activity
ALDI51_RS09025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALDI51_RS09030	COG4770	biotin carboxylase activity
ALDI51_RS09035	COG1132	(ABC) transporter
ALDI51_RS09040	COG0823	Involved in the tonB-independent uptake of proteins
ALDI51_RS09050	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ALDI51_RS09055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALDI51_RS09075	COG0741	lytic transglycosylase activity
ALDI51_RS09075	COG1388	LysM domain
ALDI51_RS09080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALDI51_RS09085	COG2226	methyltransferase
ALDI51_RS09090	COG0328	RNA-DNA hybrid ribonuclease activity
ALDI51_RS09100	COG0303	'Molybdopterin
ALDI51_RS09110	COG0746	molybdenum cofactor guanylyltransferase activity
ALDI51_RS09115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALDI51_RS09145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALDI51_RS09150	COG0129	dihydroxy-acid dehydratase activity
ALDI51_RS09160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS09175	COG2271	Major facilitator Superfamily
ALDI51_RS09195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS09200	COG0835	chemotaxis
ALDI51_RS09230	COG0347	Belongs to the P(II) protein family
ALDI51_RS09260	COG1595	DNA-templated transcription, initiation
ALDI51_RS09265	COG0028	Belongs to the TPP enzyme family
ALDI51_RS09270	COG0440	acetolactate synthase activity
ALDI51_RS09275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALDI51_RS09280	COG1183	phosphatidylcholine synthase activity
ALDI51_RS09305	COG0583	DNA-binding transcription factor activity
ALDI51_RS09315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALDI51_RS09325	COG1414	Transcriptional regulator
ALDI51_RS09330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALDI51_RS09335	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALDI51_RS09335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALDI51_RS09335	COG0506	proline dehydrogenase activity
ALDI51_RS09355	COG1024	Enoyl-CoA hydratase
ALDI51_RS09360	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS09375	COG2022	thiamine diphosphate biosynthetic process
ALDI51_RS09390	COG0351	phosphomethylpyrimidine kinase
ALDI51_RS09405	COG0492	ferredoxin-NADP+ reductase activity
ALDI51_RS09410	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALDI51_RS09450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALDI51_RS09450	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ALDI51_RS09455	COG2860	membrane
ALDI51_RS09460	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ALDI51_RS09465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALDI51_RS09470	COG0431	NADPH-dependent FMN reductase
ALDI51_RS09475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ALDI51_RS09480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALDI51_RS09485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALDI51_RS09490	COG1116	anion transmembrane transporter activity
ALDI51_RS09500	COG0583	DNA-binding transcription factor activity
ALDI51_RS09525	COG1116	anion transmembrane transporter activity
ALDI51_RS09535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALDI51_RS09565	COG2274	protein secretion by the type I secretion system
ALDI51_RS09570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS09575	COG1538	Outer membrane efflux protein
ALDI51_RS09590	COG3039	Transposase
ALDI51_RS09640	COG1396	sequence-specific DNA binding
ALDI51_RS09640	COG3800	Transcriptional regulator
ALDI51_RS09660	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ALDI51_RS09675	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS09710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALDI51_RS09715	COG1011	Hydrolase
ALDI51_RS09740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALDI51_RS09745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALDI51_RS09750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALDI51_RS09755	COG0741	lytic transglycosylase activity
ALDI51_RS09785	COG0557	exoribonuclease II activity
ALDI51_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS09800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALDI51_RS09800	COG2010	Cytochrome c
ALDI51_RS09810	COG0779	Required for maturation of 30S ribosomal subunits
ALDI51_RS09815	COG0195	Participates in both transcription termination and antitermination
ALDI51_RS09820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALDI51_RS09825	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALDI51_RS09830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALDI51_RS09845	COG1024	Enoyl-CoA hydratase
ALDI51_RS09865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALDI51_RS09870	COG2867	negative regulation of translational initiation
ALDI51_RS09890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALDI51_RS09890	COG0519	Catalyzes the synthesis of GMP from XMP
ALDI51_RS09895	COG0582	viral genome integration into host DNA
ALDI51_RS09910	COG0642	Histidine kinase
ALDI51_RS09945	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ALDI51_RS09955	COG4771	TonB-dependent receptor
ALDI51_RS09960	COG2814	Major facilitator Superfamily
ALDI51_RS09970	COG4774	siderophore transport
ALDI51_RS09980	COG1132	(ABC) transporter
ALDI51_RS09980	COG2375	cellular response to nickel ion
ALDI51_RS10000	COG4771	TonB-dependent receptor
ALDI51_RS10015	COG0372	Belongs to the citrate synthase family
ALDI51_RS10020	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ALDI51_RS10025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALDI51_RS10030	COG1053	succinate dehydrogenase
ALDI51_RS10035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ALDI51_RS10040	COG2009	succinate dehydrogenase
ALDI51_RS10045	COG2188	Transcriptional regulator
ALDI51_RS10050	COG0039	L-malate dehydrogenase activity
ALDI51_RS10055	COG4106	trans-aconitate 2-methyltransferase activity
ALDI51_RS10070	COG1049	propionate catabolic process, 2-methylcitrate cycle
ALDI51_RS10080	COG0583	DNA-binding transcription factor activity
ALDI51_RS10085	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS10095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS10110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALDI51_RS10130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALDI51_RS10145	COG3608	succinylglutamate desuccinylase aspartoacylase
ALDI51_RS10145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ALDI51_RS10160	COG0826	peptidase U32
ALDI51_RS10180	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ALDI51_RS10195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ALDI51_RS10200	COG1845	cytochrome c oxidase, subunit III
ALDI51_RS10205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALDI51_RS10210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALDI51_RS10215	COG0477	Major facilitator Superfamily
ALDI51_RS10235	COG0824	Thioesterase
ALDI51_RS10240	COG0436	Aminotransferase
ALDI51_RS10245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALDI51_RS10250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALDI51_RS10270	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS10275	COG2918	glutathione biosynthetic process
ALDI51_RS10280	COG1289	transmembrane transporter activity
ALDI51_RS10290	COG0251	oxidation-reduction process
ALDI51_RS10320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ALDI51_RS10330	COG0564	pseudouridine synthase activity
ALDI51_RS10385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALDI51_RS10395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALDI51_RS10410	COG3384	dioxygenase
ALDI51_RS10415	COG0400	carboxylic ester hydrolase activity
ALDI51_RS10445	COG0840	transmembrane signaling receptor activity
ALDI51_RS10450	COG1522	sequence-specific DNA binding
ALDI51_RS10460	COG0154	amidase activity
ALDI51_RS10470	COG0583	DNA-binding transcription factor activity
ALDI51_RS10475	COG2186	Transcriptional regulator
ALDI51_RS10480	COG2271	Major facilitator Superfamily
ALDI51_RS10485	COG2084	Dehydrogenase
ALDI51_RS10490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALDI51_RS10495	COG3395	kinase activity
ALDI51_RS10500	COG0235	Class ii aldolase
ALDI51_RS10505	COG3622	Belongs to the hyi family
ALDI51_RS10520	COG3228	Belongs to the MtfA family
ALDI51_RS10525	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALDI51_RS10550	COG0215	cysteine-tRNA ligase activity
ALDI51_RS10565	COG0037	tRNA processing
ALDI51_RS10585	COG1309	transcriptional regulator
ALDI51_RS10600	COG1136	(ABC) transporter
ALDI51_RS10605	COG2951	lytic endotransglycosylase activity
ALDI51_RS10610	COG2925	Exonuclease
ALDI51_RS10615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ALDI51_RS10620	COG0628	permease
ALDI51_RS10625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALDI51_RS10635	COG0625	glutathione transferase activity
ALDI51_RS10640	COG0433	COG0433 Predicted ATPase
ALDI51_RS10645	COG0217	transcriptional regulatory protein
ALDI51_RS10650	COG0151	Belongs to the GarS family
ALDI51_RS10655	COG0408	coproporphyrinogen oxidase activity
ALDI51_RS10660	COG0799	negative regulation of ribosome biogenesis
ALDI51_RS10665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALDI51_RS10670	COG0424	maF-like protein
ALDI51_RS10685	COG0535	radical SAM domain protein
ALDI51_RS10700	COG3391	amine dehydrogenase activity
ALDI51_RS10705	COG2010	Cytochrome c
ALDI51_RS10715	COG1648	precorrin-2 dehydrogenase activity
ALDI51_RS10715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALDI51_RS10720	COG1530	ribonuclease E activity
ALDI51_RS10725	COG3706	GGDEF domain
ALDI51_RS10730	COG0583	DNA-binding transcription factor activity
ALDI51_RS10755	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS10760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALDI51_RS10775	COG0436	Aminotransferase
ALDI51_RS10780	COG0583	DNA-binding transcription factor activity
ALDI51_RS10800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALDI51_RS10820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS10835	COG1473	amidohydrolase
ALDI51_RS10850	COG0589	response to stress
ALDI51_RS10865	COG0183	Belongs to the thiolase family
ALDI51_RS10870	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS10885	COG0545	Peptidyl-prolyl cis-trans isomerase
ALDI51_RS10890	COG2197	response regulator
ALDI51_RS10905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALDI51_RS10925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALDI51_RS10930	COG3048	D-serine ammonia-lyase activity
ALDI51_RS10935	COG1739	Uncharacterized protein family UPF0029
ALDI51_RS10940	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ALDI51_RS10955	COG0556	nucleotide-excision repair
ALDI51_RS10960	COG1959	2 iron, 2 sulfur cluster binding
ALDI51_RS10965	COG1104	cysteine desulfurase activity
ALDI51_RS10970	COG0822	iron-sulfur transferase activity
ALDI51_RS10985	COG0443	Heat shock 70 kDa protein
ALDI51_RS10990	COG0633	Ferredoxin
ALDI51_RS10995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALDI51_RS11010	COG0579	oxidoreductase
ALDI51_RS11030	COG0167	dihydroorotate dehydrogenase activity
ALDI51_RS11035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALDI51_RS11045	COG0339	signal peptide processing
ALDI51_RS11050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALDI51_RS11055	COG4566	intracellular signal transduction
ALDI51_RS11065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALDI51_RS11070	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS11075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALDI51_RS11115	COG0583	DNA-binding transcription factor activity
ALDI51_RS11120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALDI51_RS11125	COG2079	MmgE PrpD family protein
ALDI51_RS11130	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS11165	COG0791	NLP P60 protein
ALDI51_RS11170	COG1113	amino acid transport
ALDI51_RS11175	COG2814	Major facilitator Superfamily
ALDI51_RS11185	COG1742	UPF0060 membrane protein
ALDI51_RS11195	COG1196	nuclear chromosome segregation
ALDI51_RS11210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALDI51_RS11215	COG1278	Cold shock
ALDI51_RS11220	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALDI51_RS11255	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALDI51_RS11260	COG0183	Belongs to the thiolase family
ALDI51_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS11270	COG0488	(ABC) transporter
ALDI51_RS11275	COG2890	protein-(glutamine-N5) methyltransferase activity
ALDI51_RS11280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALDI51_RS11290	COG2171	N-acyltransferase activity
ALDI51_RS11300	COG2878	Part of a membrane complex involved in electron transport
ALDI51_RS11325	COG1022	Amp-dependent synthetase and ligase
ALDI51_RS11330	COG1802	Transcriptional regulator
ALDI51_RS11335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALDI51_RS11345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS11355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALDI51_RS11355	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALDI51_RS11360	COG1703	isobutyryl-CoA mutase activity
ALDI51_RS11365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS11370	COG4770	biotin carboxylase activity
ALDI51_RS11385	COG0789	Transcriptional regulator
ALDI51_RS11400	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS11410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALDI51_RS11425	COG0642	Histidine kinase
ALDI51_RS11440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALDI51_RS11455	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALDI51_RS11500	COG1763	Mo-molybdopterin cofactor biosynthetic process
ALDI51_RS11505	COG0243	molybdopterin cofactor binding
ALDI51_RS11510	COG3328	transposase activity
ALDI51_RS11520	COG1879	ABC-type sugar transport system periplasmic component
ALDI51_RS11535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALDI51_RS11540	COG1902	pentaerythritol trinitrate reductase activity
ALDI51_RS11555	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS11565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS11575	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS11580	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ALDI51_RS11585	COG1024	Enoyl-CoA hydratase
ALDI51_RS11590	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11595	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11605	COG1024	Enoyl-CoA hydratase
ALDI51_RS11605	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS11610	COG1024	Enoyl-CoA hydratase
ALDI51_RS11615	COG0183	Belongs to the thiolase family
ALDI51_RS11630	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11635	COG1024	Enoyl-CoA hydratase
ALDI51_RS11640	COG0183	Belongs to the thiolase family
ALDI51_RS11650	COG0183	Belongs to the thiolase family
ALDI51_RS11655	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS11670	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11675	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11695	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS11715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALDI51_RS11745	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS11755	COG1024	Enoyl-CoA hydratase
ALDI51_RS11765	COG1064	alcohol dehydrogenase
ALDI51_RS11770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS11775	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS11805	COG4120	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS11815	COG3284	Transcriptional regulator
ALDI51_RS11835	COG0095	Lipoate-protein ligase
ALDI51_RS11840	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS11845	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS11845	COG0022	dehydrogenase e1 component
ALDI51_RS11850	COG0022	dehydrogenase e1 component
ALDI51_RS11855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALDI51_RS11865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALDI51_RS11875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALDI51_RS11875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALDI51_RS11885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ALDI51_RS11890	COG0509	glycine decarboxylation via glycine cleavage system
ALDI51_RS11895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALDI51_RS11895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALDI51_RS11905	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ALDI51_RS11910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALDI51_RS11925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALDI51_RS11940	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS11960	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALDI51_RS11965	COG0714	Associated with various cellular activities
ALDI51_RS11980	COG2951	lytic endotransglycosylase activity
ALDI51_RS11990	COG0683	leucine binding
ALDI51_RS12000	COG1136	(ABC) transporter
ALDI51_RS12000	COG0577	efflux transmembrane transporter activity
ALDI51_RS12005	COG0577	efflux transmembrane transporter activity
ALDI51_RS12005	COG1136	(ABC) transporter
ALDI51_RS12020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALDI51_RS12025	COG0516	GMP reductase activity
ALDI51_RS12025	COG0517	IMP dehydrogenase activity
ALDI51_RS12035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS12040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS12045	COG1538	Outer membrane efflux protein
ALDI51_RS12050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALDI51_RS12060	COG0243	molybdopterin cofactor binding
ALDI51_RS12065	COG2223	nitrite transmembrane transporter activity
ALDI51_RS12070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALDI51_RS12080	COG1607	acyl-coa hydrolase
ALDI51_RS12085	COG2081	HI0933 family
ALDI51_RS12120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALDI51_RS12125	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS12130	COG1024	Enoyl-CoA hydratase
ALDI51_RS12135	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS12135	COG0022	dehydrogenase e1 component
ALDI51_RS12140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALDI51_RS12165	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS12185	COG0822	iron-sulfur transferase activity
ALDI51_RS12190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALDI51_RS12200	COG0396	ATPase activity
ALDI51_RS12205	COG0719	Fe-S assembly protein
ALDI51_RS12210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALDI51_RS12220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALDI51_RS12240	COG2755	lipolytic protein G-D-S-L family
ALDI51_RS12240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ALDI51_RS12245	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ALDI51_RS12245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALDI51_RS12260	COG2186	Transcriptional regulator
ALDI51_RS12265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALDI51_RS12270	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ALDI51_RS12275	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALDI51_RS12280	COG4208	sulfate ABC transporter
ALDI51_RS12290	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALDI51_RS12305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ALDI51_RS12315	COG1464	Belongs to the NlpA lipoprotein family
ALDI51_RS12320	COG2011	ABC-type metal ion transport system permease component
ALDI51_RS12325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ALDI51_RS12335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALDI51_RS12340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ALDI51_RS12345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALDI51_RS12365	COG4149	molybdate abc transporter
ALDI51_RS12380	COG4106	trans-aconitate 2-methyltransferase activity
ALDI51_RS12385	COG1120	ATPase activity
ALDI51_RS12390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALDI51_RS12405	COG4206	TonB-dependent receptor
ALDI51_RS12445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALDI51_RS12450	COG0254	rRNA binding
ALDI51_RS12460	COG0534	Mate efflux family protein
ALDI51_RS12475	COG0704	Plays a role in the regulation of phosphate uptake
ALDI51_RS12480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALDI51_RS12485	COG0581	inorganic phosphate transmembrane transporter activity
ALDI51_RS12490	COG0573	inorganic phosphate transmembrane transporter activity
ALDI51_RS12495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ALDI51_RS12525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALDI51_RS12535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALDI51_RS12540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ALDI51_RS12545	COG1534	Rna-binding protein
ALDI51_RS12560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALDI51_RS12565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALDI51_RS12570	COG0505	Belongs to the CarA family
ALDI51_RS12590	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS12595	COG2205	protein histidine kinase activity
ALDI51_RS12605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ALDI51_RS12610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ALDI51_RS12630	COG0789	Transcriptional regulator
ALDI51_RS12635	COG0776	regulation of translation
ALDI51_RS12640	COG0072	phenylalanine-tRNA ligase activity
ALDI51_RS12640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALDI51_RS12645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALDI51_RS12650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALDI51_RS12655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALDI51_RS12660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALDI51_RS12665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALDI51_RS12690	COG0582	viral genome integration into host DNA
ALDI51_RS12825	COG5489	Protein of unknown function (DUF736)
ALDI51_RS12830	COG1396	sequence-specific DNA binding
ALDI51_RS12855	COG1192	Involved in chromosome partitioning
ALDI51_RS12870	COG4959	Type IV secretory pathway protease TraF
ALDI51_RS12900	COG3038	cytochrome b561
ALDI51_RS12935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALDI51_RS12940	COG0583	DNA-binding transcription factor activity
ALDI51_RS12960	COG4962	Type ii secretion system protein e
ALDI51_RS12965	COG3838	Conjugal transfer protein Trbc
ALDI51_RS12975	COG3451	type IV secretory pathway VirB4
ALDI51_RS13040	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ALDI51_RS13045	COG0670	Belongs to the BI1 family
ALDI51_RS13065	COG2076	Multidrug Resistance protein
ALDI51_RS13080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ALDI51_RS13090	COG5507	3-demethylubiquinone-9 3-methyltransferase
ALDI51_RS13120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALDI51_RS13125	COG4181	ATPase activity
ALDI51_RS13140	COG0626	cystathionine gamma-synthase activity
ALDI51_RS13165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALDI51_RS13175	COG2133	pyrroloquinoline quinone binding
ALDI51_RS13180	COG0583	DNA-binding transcription factor activity
ALDI51_RS13195	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS13220	COG0133	tryptophan synthase activity
ALDI51_RS13225	COG3171	Protein conserved in bacteria
ALDI51_RS13230	COG2721	sulfolactate sulfo-lyase activity
ALDI51_RS13235	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS13240	COG4948	Mandelate Racemase Muconate Lactonizing
ALDI51_RS13250	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS13255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALDI51_RS13260	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS13265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALDI51_RS13270	COG4948	Mandelate Racemase Muconate Lactonizing
ALDI51_RS13275	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS13280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALDI51_RS13285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALDI51_RS13290	COG1741	Belongs to the pirin family
ALDI51_RS13295	COG0583	DNA-binding transcription factor activity
ALDI51_RS13300	COG0493	'glutamate synthase
ALDI51_RS13300	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ALDI51_RS13305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALDI51_RS13310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALDI51_RS13320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALDI51_RS13325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ALDI51_RS13330	COG0564	pseudouridine synthase activity
ALDI51_RS13335	COG0045	succinate-CoA ligase (ADP-forming) activity
ALDI51_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALDI51_RS13335	COG1042	CoA-binding domain protein
ALDI51_RS13350	COG2169	Transcriptional regulator
ALDI51_RS13370	COG1619	proteins homologs of microcin C7 resistance protein MccF
ALDI51_RS13385	COG0826	peptidase U32
ALDI51_RS13395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALDI51_RS13400	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ALDI51_RS13405	COG3047	cAMP biosynthetic process
ALDI51_RS13410	COG2354	Protein conserved in bacteria
ALDI51_RS13415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALDI51_RS13415	COG0047	phosphoribosylformylglycinamidine synthase activity
ALDI51_RS13420	COG0024	Methionine aminopeptidase
ALDI51_RS13430	COG2233	PERMEase
ALDI51_RS13435	COG0242	peptide deformylase activity
ALDI51_RS13440	COG2832	Protein of unknown function (DUF454)
ALDI51_RS13455	COG0735	belongs to the Fur family
ALDI51_RS13465	COG1136	(ABC) transporter
ALDI51_RS13465	COG0577	efflux transmembrane transporter activity
ALDI51_RS13470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS13505	COG1595	DNA-templated transcription, initiation
ALDI51_RS13515	COG3712	iron ion homeostasis
ALDI51_RS13520	COG1595	DNA-templated transcription, initiation
ALDI51_RS13540	COG3712	iron ion homeostasis
ALDI51_RS13545	COG1595	DNA-templated transcription, initiation
ALDI51_RS13570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALDI51_RS13575	COG1570	exodeoxyribonuclease VII activity
ALDI51_RS13580	COG0811	peptide transport
ALDI51_RS13590	COG1663	tetraacyldisaccharide 4'-kinase activity
ALDI51_RS13595	COG2835	tetraacyldisaccharide 4'-kinase activity
ALDI51_RS13600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ALDI51_RS13605	COG0563	adenylate kinase activity
ALDI51_RS13610	COG0252	asparaginase activity
ALDI51_RS13615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ALDI51_RS13625	COG1643	Atp-dependent helicase
ALDI51_RS13630	COG0183	Belongs to the thiolase family
ALDI51_RS13635	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS13640	COG1268	BioY protein
ALDI51_RS13650	COG1122	ATPase activity
ALDI51_RS13665	COG0346	lactoylglutathione lyase activity
ALDI51_RS13670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ALDI51_RS13675	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALDI51_RS13695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALDI51_RS13700	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS13705	COG3485	protocatechuate 3,4-dioxygenase
ALDI51_RS13720	COG0542	response to heat
ALDI51_RS13725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALDI51_RS13740	COG1199	ATP-dependent helicase activity
ALDI51_RS13745	COG0631	protein serine/threonine phosphatase activity
ALDI51_RS13755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ALDI51_RS13760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALDI51_RS13765	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS13770	COG0567	Dehydrogenase, E1 component
ALDI51_RS13775	COG0628	permease
ALDI51_RS13800	COG0589	response to stress
ALDI51_RS13805	COG4172	Belongs to the ABC transporter superfamily
ALDI51_RS13810	COG4239	(ABC) transporter, permease
ALDI51_RS13815	COG4174	ABC transporter (Permease)
ALDI51_RS13835	COG0697	spore germination
ALDI51_RS13840	COG2841	Protein conserved in bacteria
ALDI51_RS13845	COG1793	dna ligase
ALDI51_RS13850	COG0861	Integral membrane protein TerC family
ALDI51_RS13870	COG0583	DNA-binding transcription factor activity
ALDI51_RS13875	COG0028	Belongs to the TPP enzyme family
ALDI51_RS13935	COG3039	Transposase
ALDI51_RS13945	COG0583	DNA-binding transcription factor activity
ALDI51_RS13950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALDI51_RS13960	COG0415	Belongs to the DNA photolyase family
ALDI51_RS13965	COG2814	Major facilitator Superfamily
ALDI51_RS13980	COG2130	NADP-dependent
ALDI51_RS14010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALDI51_RS14030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALDI51_RS14035	COG0077	Prephenate dehydratase
ALDI51_RS14035	COG1605	Chorismate mutase
ALDI51_RS14040	COG0287	Prephenate dehydrogenase
ALDI51_RS14045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALDI51_RS14055	COG0776	regulation of translation
ALDI51_RS14070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALDI51_RS14075	COG1125	glycine betaine transport
ALDI51_RS14075	COG0517	IMP dehydrogenase activity
ALDI51_RS14080	COG0688	phosphatidylethanolamine metabolic process
ALDI51_RS14095	COG1959	2 iron, 2 sulfur cluster binding
ALDI51_RS14105	COG0582	viral genome integration into host DNA
ALDI51_RS14160	COG0629	single-stranded DNA binding
ALDI51_RS14165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALDI51_RS14260	COG0640	Transcriptional regulator
ALDI51_RS14280	COG0798	PFAM Bile acid sodium symporter
ALDI51_RS14290	COG0431	NADPH-dependent FMN reductase
ALDI51_RS14465	COG2205	protein histidine kinase activity
ALDI51_RS14475	COG2132	Multicopper oxidase
ALDI51_RS14550	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS14565	COG0789	Transcriptional regulator
ALDI51_RS14580	COG0789	Transcriptional regulator
ALDI51_RS14600	COG0642	Histidine kinase
ALDI51_RS14635	COG2116	formate transmembrane transporter activity
ALDI51_RS14640	COG2132	Multicopper oxidase
ALDI51_RS14645	COG0789	Transcriptional regulator
ALDI51_RS14650	COG0347	Belongs to the P(II) protein family
ALDI51_RS14660	COG0723	plastoquinol--plastocyanin reductase activity
ALDI51_RS14670	COG2132	Multicopper oxidase
ALDI51_RS14685	COG0583	DNA-binding transcription factor activity
ALDI51_RS14715	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS14720	COG0642	Histidine kinase
ALDI51_RS14735	COG0583	DNA-binding transcription factor activity
ALDI51_RS14740	COG0473	3-isopropylmalate dehydrogenase activity
ALDI51_RS14745	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALDI51_RS14760	COG2721	sulfolactate sulfo-lyase activity
ALDI51_RS14765	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS14785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ALDI51_RS14800	COG1228	amidohydrolase
ALDI51_RS14810	COG1126	abc transporter atp-binding protein
ALDI51_RS14815	COG0765	amino acid transport
ALDI51_RS14820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS14830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ALDI51_RS14835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ALDI51_RS14845	COG2986	histidine ammonia-lyase
ALDI51_RS14850	COG2188	Transcriptional regulator
ALDI51_RS14860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALDI51_RS14880	COG0583	DNA-binding transcription factor activity
ALDI51_RS14895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALDI51_RS14900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS14905	COG0583	DNA-binding transcription factor activity
ALDI51_RS14915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALDI51_RS14925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALDI51_RS14940	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ALDI51_RS14970	COG0753	catalase activity
ALDI51_RS14975	COG3634	alkyl hydroperoxide reductase activity
ALDI51_RS15000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALDI51_RS15005	COG0181	hydroxymethylbilane synthase activity
ALDI51_RS15025	COG3278	Belongs to the heme-copper respiratory oxidase family
ALDI51_RS15050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALDI51_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS15065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALDI51_RS15070	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALDI51_RS15080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALDI51_RS15085	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS15090	COG0410	ABC transporter
ALDI51_RS15115	COG2186	Transcriptional regulator
ALDI51_RS15120	COG0525	valine-tRNA ligase activity
ALDI51_RS15125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ALDI51_RS15130	COG0425	Belongs to the sulfur carrier protein TusA family
ALDI51_RS15135	COG2816	NAD+ diphosphatase activity
ALDI51_RS15180	COG3451	type IV secretory pathway VirB4
ALDI51_RS15190	COG3838	Conjugal transfer protein Trbc
ALDI51_RS15195	COG4962	Type ii secretion system protein e
ALDI51_RS15215	COG0583	DNA-binding transcription factor activity
ALDI51_RS15230	COG0589	response to stress
ALDI51_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS15250	COG1309	transcriptional regulator
ALDI51_RS15265	COG1131	(ABC) transporter
ALDI51_RS15270	COG0842	Transport permease protein
ALDI51_RS15275	COG0842	Transport permease protein
ALDI51_RS15285	COG1454	alcohol dehydrogenase
ALDI51_RS15295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALDI51_RS15300	COG1611	Belongs to the LOG family
ALDI51_RS15305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ALDI51_RS15325	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ALDI51_RS15350	COG1595	DNA-templated transcription, initiation
ALDI51_RS15370	COG1477	protein flavinylation
ALDI51_RS15380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS15400	COG4959	Type IV secretory pathway protease TraF
ALDI51_RS15415	COG1192	Involved in chromosome partitioning
ALDI51_RS15440	COG1396	sequence-specific DNA binding
ALDI51_RS15445	COG5489	Protein of unknown function (DUF736)
ALDI51_RS15480	COG0640	Transcriptional regulator
ALDI51_RS15495	COG0798	PFAM Bile acid sodium symporter
ALDI51_RS15500	COG2226	methyltransferase
ALDI51_RS15520	COG2003	Belongs to the UPF0758 family
ALDI51_RS15530	COG0464	growth
ALDI51_RS15545	COG3657	addiction module killer protein
ALDI51_RS15555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALDI51_RS15575	COG0322	excinuclease ABC activity
ALDI51_RS15610	COG2003	Belongs to the UPF0758 family
ALDI51_RS15615	COG0431	NADPH-dependent FMN reductase
ALDI51_RS15630	COG2226	methyltransferase
ALDI51_RS15635	COG0798	PFAM Bile acid sodium symporter
ALDI51_RS15650	COG0640	Transcriptional regulator
ALDI51_RS15700	COG5489	Protein of unknown function (DUF736)
ALDI51_RS15730	COG1192	Involved in chromosome partitioning
ALDI51_RS15745	COG4959	Type IV secretory pathway protease TraF
ALDI51_RS15765	COG2205	protein histidine kinase activity
ALDI51_RS15845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS15850	COG0583	DNA-binding transcription factor activity
ALDI51_RS15870	COG4962	Type ii secretion system protein e
ALDI51_RS15885	COG3451	type IV secretory pathway VirB4
ALDI51_RS15895	COG3846	protein secretion by the type IV secretion system
ALDI51_RS15910	COG2948	multi-organism process
ALDI51_RS15950	COG0587	DNA-directed DNA polymerase activity
ALDI51_RS15970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALDI51_RS15970	COG1199	ATP-dependent helicase activity
ALDI51_RS16170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALDI51_RS16185	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ALDI51_RS16195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ALDI51_RS16200	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS16215	COG1802	Transcriptional regulator
ALDI51_RS16220	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS16220	COG1024	Enoyl-CoA hydratase
ALDI51_RS16225	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS16230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALDI51_RS16240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALDI51_RS16245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALDI51_RS16260	COG0582	viral genome integration into host DNA
ALDI51_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS16290	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS16295	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS16320	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS16340	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ALDI51_RS16355	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS16360	COG0583	DNA-binding transcription factor activity
ALDI51_RS16385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALDI51_RS16390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALDI51_RS16395	COG0740	serine-type endopeptidase activity
ALDI51_RS16400	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALDI51_RS16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS16425	COG1562	ergosterol biosynthetic process
ALDI51_RS16430	COG0840	transmembrane signaling receptor activity
ALDI51_RS16435	COG1233	COG1233 Phytoene dehydrogenase and related
ALDI51_RS16445	COG1295	ribonuclease BN
ALDI51_RS16455	COG0277	FAD linked oxidase domain protein
ALDI51_RS16460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALDI51_RS16465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ALDI51_RS16475	COG1360	Flagellar Motor Protein
ALDI51_RS16490	COG0708	Exodeoxyribonuclease III
ALDI51_RS16510	COG0174	glutamine synthetase
ALDI51_RS16540	COG1187	pseudouridine synthase activity
ALDI51_RS16575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALDI51_RS16580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ALDI51_RS16590	COG0330	HflC and HflK could
ALDI51_RS16595	COG0330	HflC and HflK could
ALDI51_RS16600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALDI51_RS16605	COG1923	regulation of RNA biosynthetic process
ALDI51_RS16610	COG1160	GTP binding
ALDI51_RS16615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALDI51_RS16625	COG0124	histidyl-tRNA synthetase
ALDI51_RS16630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALDI51_RS16645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALDI51_RS16650	COG0105	UTP biosynthetic process
ALDI51_RS16655	COG1187	pseudouridine synthase activity
ALDI51_RS16660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALDI51_RS16665	COG0564	pseudouridine synthase activity
ALDI51_RS16675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALDI51_RS16680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALDI51_RS16690	COG3540	Alkaline phosphatase
ALDI51_RS16705	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS16755	COG0582	viral genome integration into host DNA
ALDI51_RS16760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALDI51_RS16775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALDI51_RS16790	COG1968	undecaprenyl-diphosphatase activity
ALDI51_RS16805	COG3275	phosphorelay sensor kinase activity
ALDI51_RS16810	COG3279	Response regulator of the LytR AlgR family
ALDI51_RS16815	COG2814	Major facilitator Superfamily
ALDI51_RS16825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALDI51_RS16830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALDI51_RS16835	COG2916	Histone family protein nucleoid-structuring protein H-NS
ALDI51_RS16840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALDI51_RS16850	COG3245	cytochrome
ALDI51_RS16860	COG4263	nitrous-oxide reductase activity
ALDI51_RS16880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ALDI51_RS16895	COG0513	Belongs to the DEAD box helicase family
ALDI51_RS16905	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS16910	COG4948	Mandelate Racemase Muconate Lactonizing
ALDI51_RS16915	COG2321	neutral zinc metallopeptidase
ALDI51_RS16920	COG0717	Belongs to the dCTP deaminase family
ALDI51_RS16945	COG0405	Gamma-glutamyltransferase
ALDI51_RS16955	COG1064	alcohol dehydrogenase
ALDI51_RS16980	COG2084	Dehydrogenase
ALDI51_RS16985	COG3622	Belongs to the hyi family
ALDI51_RS16990	COG3960	tartronate-semialdehyde synthase activity
ALDI51_RS16995	COG0583	DNA-binding transcription factor activity
ALDI51_RS17005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ALDI51_RS17030	COG0583	DNA-binding transcription factor activity
ALDI51_RS17035	COG2186	Transcriptional regulator
ALDI51_RS17050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALDI51_RS17060	COG0840	transmembrane signaling receptor activity
ALDI51_RS17065	COG2233	PERMEase
ALDI51_RS17070	COG0280	phosphate acetyltransferase
ALDI51_RS17070	COG0281	malic enzyme
ALDI51_RS17080	COG1289	transmembrane transporter activity
ALDI51_RS17090	COG2353	YceI-like domain
ALDI51_RS17105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALDI51_RS17110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALDI51_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS17125	COG0359	binds to the 23S rRNA
ALDI51_RS17130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALDI51_RS17135	COG2965	DNA replication, synthesis of RNA primer
ALDI51_RS17140	COG0360	Binds together with S18 to 16S ribosomal RNA
ALDI51_RS17145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALDI51_RS17150	COG0443	Heat shock 70 kDa protein
ALDI51_RS17155	COG0484	heat shock protein binding
ALDI51_RS17165	COG3033	Beta-eliminating lyase
ALDI51_RS17170	COG0826	peptidase U32
ALDI51_RS17175	COG0826	peptidase U32
ALDI51_RS17180	COG3154	lipid carrier protein
ALDI51_RS17195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ALDI51_RS17205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALDI51_RS17215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALDI51_RS17220	COG5510	response to toxic substance
ALDI51_RS17225	COG0066	3-isopropylmalate dehydratase activity
ALDI51_RS17230	COG0473	3-isopropylmalate dehydrogenase activity
ALDI51_RS17245	COG0101	tRNA pseudouridine synthase activity
ALDI51_RS17250	COG0135	phosphoribosylanthranilate isomerase activity
ALDI51_RS17255	COG0133	tryptophan synthase activity
ALDI51_RS17260	COG0159	tryptophan synthase activity
ALDI51_RS17265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALDI51_RS17270	COG0762	integral membrane protein
ALDI51_RS17290	COG0110	maltose O-acetyltransferase activity
ALDI51_RS17295	COG0438	transferase activity, transferring glycosyl groups
ALDI51_RS17310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALDI51_RS17315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALDI51_RS17320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALDI51_RS17360	COG1472	Belongs to the glycosyl hydrolase 3 family
ALDI51_RS17365	COG0736	holo-[acyl-carrier-protein] synthase activity
ALDI51_RS17370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALDI51_RS17375	COG1381	Involved in DNA repair and RecF pathway recombination
ALDI51_RS17380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALDI51_RS17385	COG0571	ribonuclease III activity
ALDI51_RS17395	COG0681	Belongs to the peptidase S26 family
ALDI51_RS17400	COG0481	GTPase activity
ALDI51_RS17405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALDI51_RS17430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALDI51_RS17435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALDI51_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS17450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALDI51_RS17455	COG0416	fatty acid biosynthetic process
ALDI51_RS17460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALDI51_RS17465	COG1399	metal-binding, possibly nucleic acid-binding protein
ALDI51_RS17470	COG0424	maF-like protein
ALDI51_RS17475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALDI51_RS17480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALDI51_RS17480	COG0616	signal peptide processing
ALDI51_RS17495	COG0564	pseudouridine synthase activity
ALDI51_RS17500	COG1530	ribonuclease E activity
ALDI51_RS17505	COG3022	response to hydroperoxide
ALDI51_RS17515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALDI51_RS17515	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALDI51_RS17520	COG0840	transmembrane signaling receptor activity
ALDI51_RS17525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALDI51_RS17530	COG0583	DNA-binding transcription factor activity
ALDI51_RS17540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS17545	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS17555	COG1304	FMN binding
ALDI51_RS17560	COG2885	chlorophyll binding
ALDI51_RS17575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALDI51_RS17590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALDI51_RS17605	COG0165	Argininosuccinate lyase
ALDI51_RS17610	COG3275	phosphorelay sensor kinase activity
ALDI51_RS17620	COG2719	SpoVR family
ALDI51_RS17625	COG2718	Belongs to the UPF0229 family
ALDI51_RS17630	COG2766	serine protein kinase
ALDI51_RS17635	COG1959	2 iron, 2 sulfur cluster binding
ALDI51_RS17640	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ALDI51_RS17670	COG0667	Aldo Keto reductase
ALDI51_RS17675	COG2900	Belongs to the SlyX family
ALDI51_RS17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALDI51_RS17685	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS17690	COG0154	amidase activity
ALDI51_RS17700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALDI51_RS17710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ALDI51_RS17715	COG1492	cobalamin metabolic process
ALDI51_RS17725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALDI51_RS17760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALDI51_RS17760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALDI51_RS17765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALDI51_RS17775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ALDI51_RS17795	COG0542	response to heat
ALDI51_RS17800	COG0314	molybdopterin synthase activity
ALDI51_RS17825	COG0303	'Molybdopterin
ALDI51_RS17830	COG1763	Mo-molybdopterin cofactor biosynthetic process
ALDI51_RS17835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ALDI51_RS17840	COG1487	ribonuclease activity
ALDI51_RS17855	COG0436	Aminotransferase
ALDI51_RS17875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS17905	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS17910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS17915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ALDI51_RS17920	COG2226	methyltransferase
ALDI51_RS17935	COG1121	(ABC) transporter
ALDI51_RS17940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALDI51_RS17960	COG4206	TonB-dependent receptor
ALDI51_RS17980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALDI51_RS17995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALDI51_RS18030	COG3278	Belongs to the heme-copper respiratory oxidase family
ALDI51_RS18050	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS18070	COG1802	Transcriptional regulator
ALDI51_RS18075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALDI51_RS18090	COG0129	dihydroxy-acid dehydratase activity
ALDI51_RS18095	COG0129	dihydroxy-acid dehydratase activity
ALDI51_RS18110	COG1136	(ABC) transporter
ALDI51_RS18115	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALDI51_RS18125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ALDI51_RS18130	COG0840	transmembrane signaling receptor activity
ALDI51_RS18135	COG0613	PHP domain protein
ALDI51_RS18140	COG0009	L-threonylcarbamoyladenylate synthase
ALDI51_RS18150	COG1994	Peptidase M50
ALDI51_RS18155	COG0180	Tryptophanyl-tRNA synthetase
ALDI51_RS18160	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS18175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALDI51_RS18200	COG3781	membrane
ALDI51_RS18205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALDI51_RS18215	COG1253	flavin adenine dinucleotide binding
ALDI51_RS18220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALDI51_RS18225	COG1047	Peptidyl-prolyl cis-trans
ALDI51_RS18230	COG2003	Belongs to the UPF0758 family
ALDI51_RS18250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALDI51_RS18255	COG0066	3-isopropylmalate dehydratase activity
ALDI51_RS18265	COG4626	Terminase
ALDI51_RS18265	COG1802	Transcriptional regulator
ALDI51_RS18290	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ALDI51_RS18295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ALDI51_RS18315	COG0437	4 iron, 4 sulfur cluster binding
ALDI51_RS18320	COG3383	formate dehydrogenase (NAD+) activity
ALDI51_RS18350	COG3383	formate dehydrogenase (NAD+) activity
ALDI51_RS18370	COG2186	Transcriptional regulator
ALDI51_RS18375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS18380	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS18400	COG0489	protein tyrosine kinase activity
ALDI51_RS18415	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ALDI51_RS18430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALDI51_RS18430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALDI51_RS18445	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALDI51_RS18470	COG0028	Belongs to the TPP enzyme family
ALDI51_RS18500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ALDI51_RS18510	COG1609	Transcriptional regulator
ALDI51_RS18520	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS18550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALDI51_RS18560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALDI51_RS18565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALDI51_RS18570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ALDI51_RS18575	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALDI51_RS18580	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ALDI51_RS18590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALDI51_RS18595	COG0588	phosphoglycerate mutase activity
ALDI51_RS18600	COG0793	Belongs to the peptidase S41A family
ALDI51_RS18605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALDI51_RS18615	COG2197	response regulator
ALDI51_RS18625	COG5487	UPF0391 membrane protein
ALDI51_RS18635	COG2823	Periplasmic or secreted lipoprotein
ALDI51_RS18640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALDI51_RS18645	COG0742	ribosomal rna small subunit methyltransferase
ALDI51_RS18650	COG0612	Peptidase, M16
ALDI51_RS18655	COG0612	Peptidase, M16
ALDI51_RS18665	COG0583	DNA-binding transcription factor activity
ALDI51_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS18685	COG4948	Mandelate Racemase Muconate Lactonizing
ALDI51_RS18715	COG2706	6-phosphogluconolactonase activity
ALDI51_RS18745	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS18760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALDI51_RS18765	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS18770	COG1999	signal sequence binding
ALDI51_RS18775	COG0109	protoheme IX farnesyltransferase activity
ALDI51_RS18810	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ALDI51_RS18815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALDI51_RS18825	COG2226	methyltransferase
ALDI51_RS18830	COG1040	competence protein
ALDI51_RS18835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALDI51_RS18855	COG1280	lysine exporter protein (LysE YggA)
ALDI51_RS18860	COG0475	glutathione-regulated potassium exporter activity
ALDI51_RS18860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ALDI51_RS18865	COG0583	DNA-binding transcription factor activity
ALDI51_RS18880	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS18905	COG1137	ATPase activity
ALDI51_RS18935	COG3485	protocatechuate 3,4-dioxygenase
ALDI51_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS18955	COG0183	Belongs to the thiolase family
ALDI51_RS18960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALDI51_RS18970	COG1414	Transcriptional regulator
ALDI51_RS18990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALDI51_RS19015	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS19020	COG1609	Transcriptional regulator
ALDI51_RS19025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19035	COG1024	Enoyl-CoA hydratase
ALDI51_RS19055	COG2911	Protein conserved in bacteria
ALDI51_RS19065	COG3039	Transposase
ALDI51_RS19100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALDI51_RS19105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALDI51_RS19130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALDI51_RS19135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALDI51_RS19135	COG0543	2 iron, 2 sulfur cluster binding
ALDI51_RS19145	COG0642	Histidine kinase
ALDI51_RS19155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALDI51_RS19165	COG1178	ABC-type Fe3 transport system permease component
ALDI51_RS19170	COG3842	ATPase activity
ALDI51_RS19185	COG0540	Belongs to the ATCase OTCase family
ALDI51_RS19190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ALDI51_RS19195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALDI51_RS19200	COG1678	Uncharacterized ACR, COG1678
ALDI51_RS19205	COG0643	Histidine kinase
ALDI51_RS19205	COG0784	Response regulator, receiver
ALDI51_RS19205	COG0643	Histidine kinase
ALDI51_RS19205	COG0784	Response regulator, receiver
ALDI51_RS19205	COG2198	Histidine kinase
ALDI51_RS19205	COG2198	Histidine kinase
ALDI51_RS19210	COG0840	transmembrane signaling receptor activity
ALDI51_RS19230	COG1773	rubredoxin
ALDI51_RS19235	COG0351	phosphomethylpyrimidine kinase
ALDI51_RS19240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALDI51_RS19245	COG0138	bifunctional purine biosynthesis protein purh
ALDI51_RS19250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ALDI51_RS19255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALDI51_RS19260	COG1238	metal cluster binding
ALDI51_RS19270	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS19275	COG1473	amidohydrolase
ALDI51_RS19290	COG0642	Histidine kinase
ALDI51_RS19300	COG0012	GTP binding
ALDI51_RS19305	COG3217	Mosc domain protein beta barrel domain protein
ALDI51_RS19305	COG0633	Ferredoxin
ALDI51_RS19310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ALDI51_RS19320	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS19325	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS19330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALDI51_RS19355	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS19360	COG2070	2-Nitropropane dioxygenase
ALDI51_RS19375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19380	COG0183	Belongs to the thiolase family
ALDI51_RS19385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALDI51_RS19395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19405	COG0583	DNA-binding transcription factor activity
ALDI51_RS19415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ALDI51_RS19425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS19430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALDI51_RS19445	COG1024	Enoyl-CoA hydratase
ALDI51_RS19475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALDI51_RS19485	COG4969	Belongs to the N-Me-Phe pilin family
ALDI51_RS19505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALDI51_RS19510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALDI51_RS19535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALDI51_RS19535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALDI51_RS19550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALDI51_RS19560	COG2264	protein methyltransferase activity
ALDI51_RS19565	COG0439	Biotin carboxylase
ALDI51_RS19570	COG0511	ligase activity, forming carbon-carbon bonds
ALDI51_RS19575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALDI51_RS19585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALDI51_RS19595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALDI51_RS19600	COG0312	modulator of DNA gyrase
ALDI51_RS19605	COG0772	Belongs to the SEDS family
ALDI51_RS19610	COG3150	esterase
ALDI51_RS19620	COG3474	cytochrome
ALDI51_RS19630	COG1595	DNA-templated transcription, initiation
ALDI51_RS19635	COG0557	exoribonuclease II activity
ALDI51_RS19645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALDI51_RS19650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALDI51_RS19680	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALDI51_RS19700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALDI51_RS19710	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALDI51_RS19725	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS19760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ALDI51_RS19765	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALDI51_RS19770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALDI51_RS19775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALDI51_RS19780	COG0772	Belongs to the SEDS family
ALDI51_RS19785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALDI51_RS19790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALDI51_RS19795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALDI51_RS19800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALDI51_RS19815	COG0275	rRNA processing
ALDI51_RS19820	COG2001	Belongs to the MraZ family
ALDI51_RS19825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALDI51_RS19830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALDI51_RS19845	COG0523	cobalamin synthesis protein
ALDI51_RS19860	COG2201	protein-glutamate methylesterase activity
ALDI51_RS19870	COG2202	Pas domain
ALDI51_RS19870	COG2205	protein histidine kinase activity
ALDI51_RS19875	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS19880	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS19885	COG0784	Response regulator, receiver
ALDI51_RS19885	COG3437	response regulator, receiver
ALDI51_RS19895	COG0784	Response regulator, receiver
ALDI51_RS19895	COG2205	protein histidine kinase activity
ALDI51_RS19895	COG5002	protein histidine kinase activity
ALDI51_RS19900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALDI51_RS19910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALDI51_RS19920	COG1187	pseudouridine synthase activity
ALDI51_RS19940	COG3568	Endonuclease Exonuclease Phosphatase
ALDI51_RS19945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALDI51_RS19950	COG0392	lysyltransferase activity
ALDI51_RS19970	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ALDI51_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS19985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ALDI51_RS19995	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS20000	COG1024	Enoyl-CoA hydratase
ALDI51_RS20050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS20055	COG1024	Enoyl-CoA hydratase
ALDI51_RS20060	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS20065	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS20070	COG0183	Belongs to the thiolase family
ALDI51_RS20075	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALDI51_RS20075	COG1024	Enoyl-CoA hydratase
ALDI51_RS20080	COG0583	DNA-binding transcription factor activity
ALDI51_RS20090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS20100	COG0583	DNA-binding transcription factor activity
ALDI51_RS20110	COG3039	Transposase
ALDI51_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS20135	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS20165	COG0501	Belongs to the peptidase M48B family
ALDI51_RS20175	COG0418	dihydroorotase activity
ALDI51_RS20185	COG3189	MarR family transcriptional regulator
ALDI51_RS20190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ALDI51_RS20195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALDI51_RS20200	COG0683	leucine binding
ALDI51_RS20215	COG0477	Major facilitator Superfamily
ALDI51_RS20220	COG3162	membrane
ALDI51_RS20260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALDI51_RS20280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS20285	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS20325	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ALDI51_RS20330	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS20335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALDI51_RS20345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALDI51_RS20350	COG2203	Gaf domain
ALDI51_RS20350	COG5001	Diguanylate cyclase
ALDI51_RS20350	COG4251	negative regulation of phosphorylation
ALDI51_RS20350	COG3706	GGDEF domain
ALDI51_RS20355	COG0747	negative chemotaxis
ALDI51_RS20365	COG5001	Diguanylate cyclase
ALDI51_RS20365	COG5002	protein histidine kinase activity
ALDI51_RS20395	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS20400	COG0183	Belongs to the thiolase family
ALDI51_RS20405	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALDI51_RS20410	COG0288	reversible hydration of carbon dioxide
ALDI51_RS20415	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS20420	COG0789	Transcriptional regulator
ALDI51_RS20450	COG0488	(ABC) transporter
ALDI51_RS20455	COG2201	protein-glutamate methylesterase activity
ALDI51_RS20460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALDI51_RS20465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALDI51_RS20470	COG0835	chemotaxis
ALDI51_RS20475	COG2198	Histidine kinase
ALDI51_RS20475	COG0643	Histidine kinase
ALDI51_RS20480	COG2201	protein-glutamate methylesterase activity
ALDI51_RS20495	COG2197	response regulator
ALDI51_RS20505	COG1987	bacterial-type flagellum assembly
ALDI51_RS20510	COG1338	Plays a role in the flagellum-specific transport system
ALDI51_RS20520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALDI51_RS20560	COG1766	The M ring may be actively involved in energy transduction
ALDI51_RS20565	COG1677	Flagellar hook-basal body complex protein FliE
ALDI51_RS20605	COG3754	Rhamnan synthesis protein F
ALDI51_RS20610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALDI51_RS20620	COG1360	Flagellar Motor Protein
ALDI51_RS20625	COG0745	RESPONSE REGULATOR receiver
ALDI51_RS20630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ALDI51_RS20655	COG1191	sigma factor activity
ALDI51_RS20670	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ALDI51_RS20675	COG1815	bacterial-type flagellum-dependent cell motility
ALDI51_RS20680	COG1558	bacterial-type flagellum-dependent cell motility
ALDI51_RS20685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ALDI51_RS20690	COG1749	Flagellar hook protein flgE
ALDI51_RS20705	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ALDI51_RS20710	COG1706	bacterial-type flagellum-dependent cell motility
ALDI51_RS20715	COG3951	Flagellar rod assembly protein muramidase FlgJ
ALDI51_RS20715	COG1705	Flagellar rod assembly protein muramidase FlgJ
ALDI51_RS20725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALDI51_RS20735	COG2070	2-Nitropropane dioxygenase
ALDI51_RS20740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALDI51_RS20750	COG0697	spore germination
ALDI51_RS20755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALDI51_RS20760	COG0625	glutathione transferase activity
ALDI51_RS20765	COG0384	phenazine biosynthesis protein PhzF
ALDI51_RS20770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALDI51_RS20795	COG2203	Gaf domain
ALDI51_RS20795	COG3706	GGDEF domain
ALDI51_RS20795	COG5001	Diguanylate cyclase
ALDI51_RS20795	COG4251	negative regulation of phosphorylation
ALDI51_RS20815	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS20825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALDI51_RS20840	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALDI51_RS20845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALDI51_RS20850	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS20860	COG1024	Enoyl-CoA hydratase
ALDI51_RS20865	COG0183	Belongs to the thiolase family
ALDI51_RS20870	COG1024	Enoyl-CoA hydratase
ALDI51_RS20875	COG1022	Amp-dependent synthetase and ligase
ALDI51_RS20910	COG0679	Auxin Efflux Carrier
ALDI51_RS20915	COG0210	DNA helicase
ALDI51_RS20940	COG0583	DNA-binding transcription factor activity
ALDI51_RS20950	COG0343	queuine tRNA-ribosyltransferase activity
ALDI51_RS20965	COG0204	Acyl-transferase
ALDI51_RS20965	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS20970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALDI51_RS20995	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS21000	COG2072	flavoprotein involved in K transport
ALDI51_RS21025	COG2365	Tyrosine phosphatase family
ALDI51_RS21035	COG0203	ribosomal protein L17
ALDI51_RS21040	COG0202	RNA polymerase activity
ALDI51_RS21045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALDI51_RS21050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALDI51_RS21055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALDI51_RS21060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ALDI51_RS21065	COG0201	protein transport
ALDI51_RS21070	COG0200	Binds to the 23S rRNA
ALDI51_RS21075	COG1841	ribosomal large subunit assembly
ALDI51_RS21080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALDI51_RS21085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALDI51_RS21090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALDI51_RS21095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALDI51_RS21100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALDI51_RS21105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALDI51_RS21110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALDI51_RS21115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALDI51_RS21120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ALDI51_RS21130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ALDI51_RS21145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALDI51_RS21155	COG0783	Belongs to the Dps family
ALDI51_RS21165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALDI51_RS21175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALDI51_RS21180	COG1024	Enoyl-CoA hydratase
ALDI51_RS21190	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS21195	COG1309	transcriptional regulator
ALDI51_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS21230	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS21235	COG1024	Enoyl-CoA hydratase
ALDI51_RS21240	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS21285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS21330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALDI51_RS21335	COG0134	indole-3-glycerol-phosphate synthase activity
ALDI51_RS21345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALDI51_RS21350	COG0512	Glutamine amidotransferase of anthranilate synthase
ALDI51_RS21455	COG0840	transmembrane signaling receptor activity
ALDI51_RS21465	COG0546	phosphoglycolate phosphatase activity
ALDI51_RS21475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALDI51_RS21480	COG2967	ApaG domain
ALDI51_RS21495	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ALDI51_RS21505	COG0583	DNA-binding transcription factor activity
ALDI51_RS21535	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS21540	COG1309	transcriptional regulator
ALDI51_RS21555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALDI51_RS21560	COG1129	ABC transporter
ALDI51_RS21560	COG0842	Transport permease protein
ALDI51_RS21565	COG0842	Transport permease protein
ALDI51_RS21575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALDI51_RS21580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALDI51_RS21590	COG0840	transmembrane signaling receptor activity
ALDI51_RS21610	COG3012	SEC-C Motif Domain Protein
ALDI51_RS21610	COG3318	Belongs to the UPF0149 family
ALDI51_RS21635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ALDI51_RS21640	COG1137	ATPase activity
ALDI51_RS21650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALDI51_RS21660	COG0018	arginyl-trna synthetase
ALDI51_RS21675	COG1301	dicarboxylic acid transport
ALDI51_RS21680	COG4191	Histidine kinase
ALDI51_RS21695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ALDI51_RS21705	COG1942	4-Oxalocrotonate Tautomerase
ALDI51_RS21715	COG0121	glutamine amidotransferase
ALDI51_RS21745	COG0189	ligase activity
ALDI51_RS21750	COG3135	benzoate transporter
ALDI51_RS21755	COG3158	transport of potassium into the cell
ALDI51_RS21765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALDI51_RS21770	COG0569	domain protein
ALDI51_RS21775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALDI51_RS21785	COG0583	DNA-binding transcription factor activity
ALDI51_RS21790	COG1024	Enoyl-CoA hydratase
ALDI51_RS21795	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS21800	COG1466	dna polymerase III delta subunit
ALDI51_RS21810	COG0495	leucyl-tRNA aminoacylation
ALDI51_RS21815	COG0668	transmembrane transport
ALDI51_RS21820	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS21825	COG4772	TonB-dependent receptor
ALDI51_RS21840	COG4654	Cytochrome c, class I
ALDI51_RS21850	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALDI51_RS21880	COG3038	cytochrome b561
ALDI51_RS21885	COG3284	Transcriptional regulator
ALDI51_RS21895	COG2202	Pas domain
ALDI51_RS21895	COG2200	EAL domain
ALDI51_RS21895	COG2199	diguanylate cyclase activity
ALDI51_RS21900	COG0840	transmembrane signaling receptor activity
ALDI51_RS21915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALDI51_RS21920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALDI51_RS21925	COG0735	belongs to the Fur family
ALDI51_RS21930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ALDI51_RS21940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ALDI51_RS21945	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALDI51_RS21950	COG3118	belongs to the thioredoxin family
ALDI51_RS21960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALDI51_RS21965	COG0009	L-threonylcarbamoyladenylate synthase
ALDI51_RS21980	COG3047	cAMP biosynthetic process
ALDI51_RS22010	COG0598	Magnesium transport protein CorA
ALDI51_RS22025	COG0318	PFAM AMP-dependent synthetase and ligase
ALDI51_RS22030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALDI51_RS22035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ALDI51_RS22050	COG0469	pyruvate kinase activity
ALDI51_RS22055	COG0006	proline dipeptidase activity
ALDI51_RS22060	COG1024	Enoyl-CoA hydratase
ALDI51_RS22075	COG0183	Belongs to the thiolase family
ALDI51_RS22085	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS22090	COG0583	DNA-binding transcription factor activity
ALDI51_RS22095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ALDI51_RS22100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALDI51_RS22105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALDI51_RS22115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ALDI51_RS22120	COG0583	DNA-binding transcription factor activity
ALDI51_RS22160	COG1047	Peptidyl-prolyl cis-trans
ALDI51_RS22165	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
ALDI51_RS22210	COG3148	PFAM DTW domain containing protein
ALDI51_RS22235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALDI51_RS22235	COG0045	succinate-CoA ligase (ADP-forming) activity
ALDI51_RS22235	COG1042	CoA-binding domain protein
ALDI51_RS22240	COG0625	glutathione transferase activity
ALDI51_RS22290	COG0551	DNA topoisomerase type I activity
ALDI51_RS22290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALDI51_RS22310	COG0604	alcohol dehydrogenase
ALDI51_RS22320	COG2030	dehydratase
ALDI51_RS22330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALDI51_RS22335	COG1846	Transcriptional regulator
ALDI51_RS22355	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS22360	COG0642	Histidine kinase
ALDI51_RS22375	COG1178	ABC-type Fe3 transport system permease component
ALDI51_RS22380	COG3842	ATPase activity
ALDI51_RS22385	COG1840	ABC-type Fe3 transport system, periplasmic component
ALDI51_RS22400	COG1012	belongs to the aldehyde dehydrogenase family
ALDI51_RS22410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALDI51_RS22415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALDI51_RS22420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALDI51_RS22435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALDI51_RS22440	COG2137	regulation of response to DNA damage stimulus
ALDI51_RS22450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALDI51_RS22455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALDI51_RS22460	COG1862	Preprotein translocase
ALDI51_RS22470	COG1522	sequence-specific DNA binding
ALDI51_RS22475	COG2814	Major facilitator Superfamily
ALDI51_RS22480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ALDI51_RS22490	COG4566	intracellular signal transduction
ALDI51_RS22510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ALDI51_RS22525	COG0625	glutathione transferase activity
ALDI51_RS22550	COG0861	Integral membrane protein TerC family
ALDI51_RS22560	COG0583	DNA-binding transcription factor activity
ALDI51_RS22575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS22580	COG1950	PFAM Membrane protein of
ALDI51_RS22585	COG4783	chaperone-mediated protein folding
ALDI51_RS22590	COG0315	cyclic pyranopterin monophosphate synthase activity
ALDI51_RS22605	COG4969	Belongs to the N-Me-Phe pilin family
ALDI51_RS22610	COG1234	tRNA 3'-trailer cleavage
ALDI51_RS22615	COG1716	ATPase activity
ALDI51_RS22625	COG0861	Integral membrane protein TerC family
ALDI51_RS22630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALDI51_RS22635	COG0045	succinate-CoA ligase (ADP-forming) activity
ALDI51_RS22640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALDI51_RS22645	COG0758	DNA mediated transformation
ALDI51_RS22655	COG0242	peptide deformylase activity
ALDI51_RS22665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALDI51_RS22680	COG0126	phosphoglycerate kinase activity
ALDI51_RS22695	COG0697	spore germination
ALDI51_RS22700	COG0284	orotidine-5'-phosphate decarboxylase activity
ALDI51_RS22705	COG0583	DNA-binding transcription factor activity
ALDI51_RS22720	COG0840	transmembrane signaling receptor activity
ALDI51_RS22730	COG2814	Major facilitator Superfamily
ALDI51_RS22735	COG0629	single-stranded DNA binding
ALDI51_RS22740	COG1620	l-lactate permease
ALDI51_RS22745	COG0482	sulfurtransferase activity
ALDI51_RS22750	COG0583	DNA-binding transcription factor activity
ALDI51_RS22755	COG2828	Protein conserved in bacteria
ALDI51_RS22765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALDI51_RS22775	COG1053	succinate dehydrogenase
ALDI51_RS22775	COG3976	FMN-binding domain protein
ALDI51_RS22795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALDI51_RS22810	COG0439	Biotin carboxylase
ALDI51_RS22815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ALDI51_RS22830	COG4771	TonB-dependent receptor
ALDI51_RS22840	COG4771	TonB-dependent receptor
ALDI51_RS22855	COG3181	Tripartite tricarboxylate transporter family receptor
ALDI51_RS22860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS22870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALDI51_RS22880	COG1280	lysine exporter protein (LysE YggA)
ALDI51_RS22910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALDI51_RS22925	COG2070	2-Nitropropane dioxygenase
ALDI51_RS22935	COG1960	acyl-CoA dehydrogenase activity
ALDI51_RS22940	COG1414	Transcriptional regulator
ALDI51_RS22945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALDI51_RS22985	COG1695	Transcriptional regulator
ALDI51_RS22995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALDI51_RS23045	COG3706	GGDEF domain
ALDI51_RS23050	COG1802	Transcriptional regulator
ALDI51_RS23060	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALDI51_RS23065	COG4177	L-phenylalanine transmembrane transporter activity
ALDI51_RS23095	COG4290	ribonuclease
ALDI51_RS23110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALDI51_RS23115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALDI51_RS23120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ALDI51_RS23130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALDI51_RS23145	COG1196	nuclear chromosome segregation
ALDI51_RS23160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALDI51_RS23165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALDI51_RS23170	COG2119	membrane
ALDI51_RS23175	COG0724	RNA recognition motif
ALDI51_RS23180	COG0724	RNA recognition motif
ALDI51_RS23185	COG0300	oxidoreductase activity
ALDI51_RS23195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALDI51_RS23210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ALDI51_RS23225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALDI51_RS23230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALDI51_RS23235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALDI51_RS23275	COG4172	Belongs to the ABC transporter superfamily
ALDI51_RS23280	COG1446	asparaginase
ALDI51_RS23290	COG0747	negative chemotaxis
ALDI51_RS23295	COG0706	membrane insertase activity
ALDI51_RS23300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALDI51_RS23305	COG0594	ribonuclease P activity
ALDI51_RS23310	COG0230	Belongs to the bacterial ribosomal protein bL34 family