locus-tag	class	description
ALIDE2_RS00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALIDE2_RS00065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS00075	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00080	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS00090	COG0439	Biotin carboxylase
ALIDE2_RS00095	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS00105	COG1254	Belongs to the acylphosphatase family
ALIDE2_RS00120	COG1199	ATP-dependent helicase activity
ALIDE2_RS00130	COG0791	NLP P60 protein
ALIDE2_RS00135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALIDE2_RS00155	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00160	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00175	COG1024	Enoyl-CoA hydratase
ALIDE2_RS00195	COG2974	May be involved in recombination
ALIDE2_RS00200	COG0700	Nucleoside recognition
ALIDE2_RS00215	COG0789	Transcriptional regulator
ALIDE2_RS00250	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS00260	COG1902	pentaerythritol trinitrate reductase activity
ALIDE2_RS00280	COG0445	tRNA wobble uridine modification
ALIDE2_RS00290	COG0357	Ribosomal RNA small subunit methyltransferase G
ALIDE2_RS00300	COG1192	Involved in chromosome partitioning
ALIDE2_RS00310	COG1475	DNA binding
ALIDE2_RS00335	COG0668	transmembrane transport
ALIDE2_RS00340	COG0277	FAD linked oxidase domain protein
ALIDE2_RS00350	COG2096	Adenosyltransferase
ALIDE2_RS00355	COG2050	protein possibly involved in aromatic compounds catabolism
ALIDE2_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS00395	COG2233	PERMEase
ALIDE2_RS00410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALIDE2_RS00415	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00425	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00430	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00440	COG1183	phosphatidylcholine synthase activity
ALIDE2_RS00460	COG0850	regulation of cytokinetic process
ALIDE2_RS00470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ALIDE2_RS00475	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00480	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS00485	COG4948	Mandelate Racemase Muconate Lactonizing
ALIDE2_RS00490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALIDE2_RS00495	COG2267	carboxylic ester hydrolase activity
ALIDE2_RS00525	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ALIDE2_RS00530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALIDE2_RS00535	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00550	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00565	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS00570	COG0514	ATP-dependent DNA helicase (RecQ)
ALIDE2_RS00600	COG3256	nitric oxide reductase
ALIDE2_RS00605	COG3604	Transcriptional regulator
ALIDE2_RS00615	COG1760	l-serine dehydratase
ALIDE2_RS00620	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS00625	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS00655	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS00660	COG0183	Belongs to the thiolase family
ALIDE2_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS00685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS00700	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00710	COG2030	dehydratase
ALIDE2_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS00755	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00760	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ALIDE2_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS00770	COG2030	dehydratase
ALIDE2_RS00775	COG1024	Enoyl-CoA hydratase
ALIDE2_RS00780	COG0427	acetyl-CoA hydrolase
ALIDE2_RS00785	COG0183	Belongs to the thiolase family
ALIDE2_RS00810	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00820	COG1473	amidohydrolase
ALIDE2_RS00830	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS00845	COG1473	amidohydrolase
ALIDE2_RS00860	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00885	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS00895	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS00900	COG1024	Enoyl-CoA hydratase
ALIDE2_RS00925	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS00935	COG0583	DNA-binding transcription factor activity
ALIDE2_RS00950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALIDE2_RS00960	COG3204	pilus organization
ALIDE2_RS00965	COG0646	methionine synthase
ALIDE2_RS00965	COG1410	methionine synthase
ALIDE2_RS00985	COG4372	Transposase
ALIDE2_RS01010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALIDE2_RS01030	COG0683	leucine binding
ALIDE2_RS01070	COG0347	Belongs to the P(II) protein family
ALIDE2_RS01075	COG0004	ammonium transporteR
ALIDE2_RS01105	COG2267	carboxylic ester hydrolase activity
ALIDE2_RS01115	COG3180	Ammonia monooxygenase
ALIDE2_RS01140	COG0277	FAD linked oxidase domain protein
ALIDE2_RS01150	COG0247	lactate metabolic process
ALIDE2_RS01165	COG0477	Major facilitator Superfamily
ALIDE2_RS01170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALIDE2_RS01175	COG1858	cytochrome C peroxidase
ALIDE2_RS01180	COG0625	glutathione transferase activity
ALIDE2_RS01195	COG0154	amidase activity
ALIDE2_RS01225	COG1216	Glycosyl transferase, family 2
ALIDE2_RS01245	COG0477	Major facilitator Superfamily
ALIDE2_RS01250	COG2258	MOSC domain
ALIDE2_RS01285	COG2205	protein histidine kinase activity
ALIDE2_RS01290	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS01310	COG0501	Belongs to the peptidase M48B family
ALIDE2_RS01400	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ALIDE2_RS01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALIDE2_RS01430	COG1414	Transcriptional regulator
ALIDE2_RS01450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS01455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS01475	COG3386	PFAM SMP-30 Gluconolaconase
ALIDE2_RS01485	COG2084	Dehydrogenase
ALIDE2_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS01495	COG1414	Transcriptional regulator
ALIDE2_RS01545	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS01560	COG0708	Exodeoxyribonuclease III
ALIDE2_RS01565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALIDE2_RS01575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALIDE2_RS01580	COG0154	amidase activity
ALIDE2_RS01585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALIDE2_RS01590	COG1077	Cell shape determining protein MreB Mrl
ALIDE2_RS01600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ALIDE2_RS01605	COG0768	penicillin binding
ALIDE2_RS01615	COG0730	response to heat
ALIDE2_RS01625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALIDE2_RS01630	COG1127	ABC transporter
ALIDE2_RS01635	COG3008	intermembrane lipid transfer
ALIDE2_RS01635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALIDE2_RS01645	COG0583	DNA-binding transcription factor activity
ALIDE2_RS01650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALIDE2_RS01660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS01665	COG2095	MarC family integral membrane protein
ALIDE2_RS01670	COG0412	Dienelactone hydrolase
ALIDE2_RS01695	COG0598	Magnesium transport protein CorA
ALIDE2_RS01710	COG1981	membrane
ALIDE2_RS01725	COG2945	thiolester hydrolase activity
ALIDE2_RS01730	COG1686	Belongs to the peptidase S11 family
ALIDE2_RS01735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALIDE2_RS01740	COG0049	tRNA binding
ALIDE2_RS01745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALIDE2_RS01750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALIDE2_RS01755	COG0051	transcription antitermination factor activity, RNA binding
ALIDE2_RS01760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALIDE2_RS01765	COG0088	Forms part of the polypeptide exit tunnel
ALIDE2_RS01770	COG0089	rRNA binding
ALIDE2_RS01775	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALIDE2_RS01780	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALIDE2_RS01785	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALIDE2_RS01790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALIDE2_RS01795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALIDE2_RS01800	COG0255	Belongs to the universal ribosomal protein uL29 family
ALIDE2_RS01805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALIDE2_RS01810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ALIDE2_RS01810	COG0678	peroxiredoxin activity
ALIDE2_RS01815	COG0456	acetyltransferase
ALIDE2_RS01825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALIDE2_RS01840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALIDE2_RS01845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALIDE2_RS01850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALIDE2_RS01855	COG0321	lipoyl(octanoyl) transferase activity
ALIDE2_RS01860	COG2921	Belongs to the UPF0250 family
ALIDE2_RS01870	COG0356	it plays a direct role in the translocation of protons across the membrane
ALIDE2_RS01880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALIDE2_RS01885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALIDE2_RS01890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALIDE2_RS01895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ALIDE2_RS01900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALIDE2_RS01905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALIDE2_RS01920	COG4372	Transposase
ALIDE2_RS01965	COG3245	cytochrome
ALIDE2_RS01975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS01980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS02010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALIDE2_RS02020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ALIDE2_RS02030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALIDE2_RS02035	COG0081	regulation of translation
ALIDE2_RS02040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALIDE2_RS02045	COG0222	ribosome binding
ALIDE2_RS02050	COG0085	RNA polymerase activity
ALIDE2_RS02055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALIDE2_RS02065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALIDE2_RS02065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALIDE2_RS02075	COG5000	phosphorelay sensor kinase activity
ALIDE2_RS02080	COG2204	response regulator
ALIDE2_RS02100	COG2963	transposase activity
ALIDE2_RS02165	COG0582	viral genome integration into host DNA
ALIDE2_RS02200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALIDE2_RS02205	COG0463	Glycosyl transferase, family 2
ALIDE2_RS02215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALIDE2_RS02220	COG0792	nuclease activity
ALIDE2_RS02225	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ALIDE2_RS02235	COG2084	Dehydrogenase
ALIDE2_RS02245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALIDE2_RS02255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ALIDE2_RS02270	COG2733	membrane
ALIDE2_RS02275	COG0277	FAD linked oxidase domain protein
ALIDE2_RS02280	COG0583	DNA-binding transcription factor activity
ALIDE2_RS02290	COG5001	Diguanylate cyclase
ALIDE2_RS02300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALIDE2_RS02305	COG4585	Histidine kinase
ALIDE2_RS02310	COG2197	response regulator
ALIDE2_RS02320	COG2223	nitrite transmembrane transporter activity
ALIDE2_RS02325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ALIDE2_RS02330	COG1140	nitrate reductase beta subunit
ALIDE2_RS02335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ALIDE2_RS02340	COG2181	nitrate reductase activity
ALIDE2_RS02350	COG0288	reversible hydration of carbon dioxide
ALIDE2_RS02365	COG3945	hemerythrin HHE cation binding domain
ALIDE2_RS02390	COG0243	molybdopterin cofactor binding
ALIDE2_RS02400	COG2301	Belongs to the HpcH HpaI aldolase family
ALIDE2_RS02405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS02410	COG2030	dehydratase
ALIDE2_RS02420	COG2030	dehydratase
ALIDE2_RS02440	COG1473	amidohydrolase
ALIDE2_RS02455	COG2818	Glycosylase
ALIDE2_RS02460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALIDE2_RS02500	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS02510	COG1022	Amp-dependent synthetase and ligase
ALIDE2_RS02515	COG3409	Peptidoglycan-binding domain 1 protein
ALIDE2_RS02515	COG3267	Type II secretory pathway component ExeA
ALIDE2_RS02525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALIDE2_RS02530	COG1187	pseudouridine synthase activity
ALIDE2_RS02535	COG0326	Molecular chaperone. Has ATPase activity
ALIDE2_RS02550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ALIDE2_RS02565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS02580	COG3971	2-oxopent-4-enoate hydratase activity
ALIDE2_RS02585	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALIDE2_RS02605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ALIDE2_RS02615	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS02635	COG1131	(ABC) transporter
ALIDE2_RS02640	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALIDE2_RS02645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ALIDE2_RS02650	COG5001	Diguanylate cyclase
ALIDE2_RS02650	COG3300	MHYT domain
ALIDE2_RS02655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALIDE2_RS02660	COG1490	D-aminoacyl-tRNA deacylase activity
ALIDE2_RS02665	COG0730	response to heat
ALIDE2_RS02680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS02685	COG0604	alcohol dehydrogenase
ALIDE2_RS02690	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS02695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALIDE2_RS02700	COG1702	phosphate starvation-inducible protein PhoH
ALIDE2_RS02705	COG0632	four-way junction helicase activity
ALIDE2_RS02720	COG0443	Heat shock 70 kDa protein
ALIDE2_RS02730	COG2255	four-way junction helicase activity
ALIDE2_RS02735	COG1285	pathogenesis
ALIDE2_RS02750	COG3616	Alanine racemase, N-terminal domain
ALIDE2_RS02765	COG0037	tRNA processing
ALIDE2_RS02800	COG1940	carbohydrate kinase activity
ALIDE2_RS02805	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ALIDE2_RS02810	COG3387	PFAM Glycoside hydrolase 15-related
ALIDE2_RS02815	COG1877	trehalose-phosphatase activity
ALIDE2_RS02825	COG0617	tRNA 3'-terminal CCA addition
ALIDE2_RS02845	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS02860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALIDE2_RS02865	COG0741	lytic transglycosylase activity
ALIDE2_RS02865	COG0739	heme binding
ALIDE2_RS02865	COG1196	nuclear chromosome segregation
ALIDE2_RS02880	COG3128	pkhd-type hydroxylase
ALIDE2_RS02890	COG4774	siderophore transport
ALIDE2_RS02900	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS02915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALIDE2_RS02920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALIDE2_RS02935	COG1522	sequence-specific DNA binding
ALIDE2_RS02945	COG3186	Phenylalanine-4-hydroxylase
ALIDE2_RS02955	COG0022	dehydrogenase e1 component
ALIDE2_RS02970	COG0752	glycyl-tRNA synthetase alpha subunit
ALIDE2_RS02975	COG0751	glycine-tRNA ligase activity
ALIDE2_RS02980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ALIDE2_RS02985	COG0204	Acyl-transferase
ALIDE2_RS03000	COG1652	LysM domain
ALIDE2_RS03005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALIDE2_RS03050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALIDE2_RS03080	COG3156	type II secretion system protein K
ALIDE2_RS03130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALIDE2_RS03135	COG1196	nuclear chromosome segregation
ALIDE2_RS03135	COG0741	lytic transglycosylase activity
ALIDE2_RS03135	COG0739	heme binding
ALIDE2_RS03145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALIDE2_RS03150	COG1309	transcriptional regulator
ALIDE2_RS03160	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS03170	COG1024	Enoyl-CoA hydratase
ALIDE2_RS03170	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS03175	COG0183	Belongs to the thiolase family
ALIDE2_RS03185	COG1024	Enoyl-CoA hydratase
ALIDE2_RS03200	COG5265	(ABC) transporter
ALIDE2_RS03210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALIDE2_RS03215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS03215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALIDE2_RS03220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALIDE2_RS03225	COG0583	DNA-binding transcription factor activity
ALIDE2_RS03230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS03235	COG0765	amino acid transport
ALIDE2_RS03240	COG0765	amino acid transport
ALIDE2_RS03245	COG1126	abc transporter atp-binding protein
ALIDE2_RS03250	COG2423	ornithine cyclodeaminase activity
ALIDE2_RS03260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ALIDE2_RS03270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALIDE2_RS03280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ALIDE2_RS03285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALIDE2_RS03290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ALIDE2_RS03300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALIDE2_RS03305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALIDE2_RS03310	COG0316	Belongs to the HesB IscA family
ALIDE2_RS03315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ALIDE2_RS03320	COG0739	heme binding
ALIDE2_RS03325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALIDE2_RS03330	COG0583	DNA-binding transcription factor activity
ALIDE2_RS03335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALIDE2_RS03340	COG2205	protein histidine kinase activity
ALIDE2_RS03355	COG1522	sequence-specific DNA binding
ALIDE2_RS03395	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALIDE2_RS03400	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ALIDE2_RS03405	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS03410	COG5002	protein histidine kinase activity
ALIDE2_RS03445	COG0489	protein tyrosine kinase activity
ALIDE2_RS03450	COG3267	Type II secretory pathway component ExeA
ALIDE2_RS03450	COG3409	Peptidoglycan-binding domain 1 protein
ALIDE2_RS03475	COG0367	asparagine synthase
ALIDE2_RS03480	COG0438	transferase activity, transferring glycosyl groups
ALIDE2_RS03490	COG0438	transferase activity, transferring glycosyl groups
ALIDE2_RS03520	COG0463	Glycosyl transferase, family 2
ALIDE2_RS03520	COG1216	Glycosyl transferase, family 2
ALIDE2_RS03535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALIDE2_RS03575	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS03585	COG3850	Histidine kinase
ALIDE2_RS03585	COG5002	protein histidine kinase activity
ALIDE2_RS03590	COG2204	response regulator
ALIDE2_RS03605	COG2076	Multidrug Resistance protein
ALIDE2_RS03610	COG0546	phosphoglycolate phosphatase activity
ALIDE2_RS03610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALIDE2_RS03620	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS03630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALIDE2_RS03640	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS03665	COG3045	CreA protein
ALIDE2_RS03670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALIDE2_RS03670	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALIDE2_RS03675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALIDE2_RS03675	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALIDE2_RS03680	COG1132	(ABC) transporter
ALIDE2_RS03710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ALIDE2_RS03780	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ALIDE2_RS03785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALIDE2_RS03790	COG1765	OsmC-like protein
ALIDE2_RS03795	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ALIDE2_RS03815	COG1473	amidohydrolase
ALIDE2_RS03820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALIDE2_RS03825	COG0444	Belongs to the ABC transporter superfamily
ALIDE2_RS03830	COG4608	Belongs to the ABC transporter superfamily
ALIDE2_RS03835	COG1881	PFAM PEBP family protein
ALIDE2_RS03840	COG1737	Transcriptional regulator
ALIDE2_RS03840	COG0837	glucose binding
ALIDE2_RS03845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALIDE2_RS03850	COG0166	Belongs to the GPI family
ALIDE2_RS03855	COG0459	protein refolding
ALIDE2_RS03860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALIDE2_RS03865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALIDE2_RS03870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALIDE2_RS03880	COG1560	Kdo2-lipid A biosynthetic process
ALIDE2_RS03885	COG0583	DNA-binding transcription factor activity
ALIDE2_RS03900	COG0473	3-isopropylmalate dehydrogenase activity
ALIDE2_RS03910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALIDE2_RS03920	COG1333	cytochrome c biogenesis protein
ALIDE2_RS03925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALIDE2_RS03930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ALIDE2_RS03935	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ALIDE2_RS03950	COG1965	Belongs to the frataxin family
ALIDE2_RS03995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ALIDE2_RS04030	COG0067	glutamate synthase
ALIDE2_RS04030	COG0069	glutamate synthase activity
ALIDE2_RS04030	COG0070	glutamate synthase
ALIDE2_RS04040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS04045	COG0765	amino acid transport
ALIDE2_RS04050	COG1126	abc transporter atp-binding protein
ALIDE2_RS04060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALIDE2_RS04065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ALIDE2_RS04070	COG1127	ABC transporter
ALIDE2_RS04075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALIDE2_RS04080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALIDE2_RS04100	COG2199	diguanylate cyclase activity
ALIDE2_RS04105	COG1131	(ABC) transporter
ALIDE2_RS04110	COG0842	Transport permease protein
ALIDE2_RS04115	COG5007	Belongs to the BolA IbaG family
ALIDE2_RS04120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALIDE2_RS04125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALIDE2_RS04145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALIDE2_RS04150	COG0131	Imidazoleglycerol-phosphate dehydratase
ALIDE2_RS04160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALIDE2_RS04175	COG0438	transferase activity, transferring glycosyl groups
ALIDE2_RS04205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ALIDE2_RS04210	COG0107	imidazoleglycerol-phosphate synthase activity
ALIDE2_RS04215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALIDE2_RS04220	COG0140	phosphoribosyl-ATP diphosphatase activity
ALIDE2_RS04235	COG0537	adenosine 5'-monophosphoramidase activity
ALIDE2_RS04240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALIDE2_RS04245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALIDE2_RS04250	COG0805	protein transport
ALIDE2_RS04255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS04260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALIDE2_RS04265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALIDE2_RS04270	COG1970	mechanosensitive ion channel activity
ALIDE2_RS04275	COG0723	plastoquinol--plastocyanin reductase activity
ALIDE2_RS04280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALIDE2_RS04285	COG2857	Cytochrome c1
ALIDE2_RS04290	COG0625	glutathione transferase activity
ALIDE2_RS04295	COG2969	positive regulation of protein catabolic process
ALIDE2_RS04310	COG0653	protein targeting
ALIDE2_RS04315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALIDE2_RS04325	COG0494	nUDIX hydrolase
ALIDE2_RS04330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ALIDE2_RS04335	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ALIDE2_RS04340	COG0237	dephospho-CoA kinase activity
ALIDE2_RS04430	COG0142	geranyltranstransferase activity
ALIDE2_RS04435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALIDE2_RS04440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ALIDE2_RS04445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALIDE2_RS04450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ALIDE2_RS04455	COG0494	nUDIX hydrolase
ALIDE2_RS04460	COG0442	prolyl-tRNA aminoacylation
ALIDE2_RS04470	COG1253	flavin adenine dinucleotide binding
ALIDE2_RS04475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALIDE2_RS04480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ALIDE2_RS04485	COG2890	protein-(glutamine-N5) methyltransferase activity
ALIDE2_RS04490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALIDE2_RS04495	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALIDE2_RS04520	COG3264	Mechanosensitive ion channel
ALIDE2_RS04520	COG1511	domain protein
ALIDE2_RS04525	COG0584	glycerophosphoryl diester phosphodiesterase
ALIDE2_RS04530	COG3842	ATPase activity
ALIDE2_RS04535	COG0395	ABC-type sugar transport system, permease component
ALIDE2_RS04540	COG1175	transmembrane transport
ALIDE2_RS04545	COG1653	transport
ALIDE2_RS04550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALIDE2_RS04570	COG2226	methyltransferase
ALIDE2_RS04585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALIDE2_RS04605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALIDE2_RS04620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALIDE2_RS04625	COG0302	gtp cyclohydrolase
ALIDE2_RS04640	COG4191	Histidine kinase
ALIDE2_RS04645	COG4566	intracellular signal transduction
ALIDE2_RS04650	COG3258	Cytochrome c
ALIDE2_RS04665	COG1280	lysine exporter protein (LysE YggA)
ALIDE2_RS04670	COG0154	amidase activity
ALIDE2_RS04680	COG4608	Belongs to the ABC transporter superfamily
ALIDE2_RS04685	COG0444	Belongs to the ABC transporter superfamily
ALIDE2_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALIDE2_RS04700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALIDE2_RS04705	COG0193	aminoacyl-tRNA hydrolase activity
ALIDE2_RS04710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALIDE2_RS04715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALIDE2_RS04725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALIDE2_RS04740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ALIDE2_RS04750	COG1194	a g-specific adenine glycosylase
ALIDE2_RS04755	COG1660	Displays ATPase and GTPase activities
ALIDE2_RS04760	COG0497	DNA recombination
ALIDE2_RS04765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALIDE2_RS04770	COG1420	regulation of RNA biosynthetic process
ALIDE2_RS04810	COG3385	transposase activity
ALIDE2_RS04825	COG3038	cytochrome b561
ALIDE2_RS04835	COG0642	Histidine kinase
ALIDE2_RS04860	COG2706	6-phosphogluconolactonase activity
ALIDE2_RS04865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ALIDE2_RS04895	COG4948	Mandelate Racemase Muconate Lactonizing
ALIDE2_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS04910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS04915	COG0583	DNA-binding transcription factor activity
ALIDE2_RS04925	COG0612	Peptidase, M16
ALIDE2_RS04930	COG0612	Peptidase, M16
ALIDE2_RS04935	COG0742	ribosomal rna small subunit methyltransferase
ALIDE2_RS04940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALIDE2_RS04945	COG2823	Periplasmic or secreted lipoprotein
ALIDE2_RS04965	COG2197	response regulator
ALIDE2_RS04975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALIDE2_RS04980	COG0793	Belongs to the peptidase S41A family
ALIDE2_RS04985	COG0588	phosphoglycerate mutase activity
ALIDE2_RS04990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALIDE2_RS05000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ALIDE2_RS05005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALIDE2_RS05030	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS05040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALIDE2_RS05045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALIDE2_RS05055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALIDE2_RS05070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ALIDE2_RS05100	COG0028	Belongs to the TPP enzyme family
ALIDE2_RS05120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ALIDE2_RS05130	COG3135	benzoate transporter
ALIDE2_RS05145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALIDE2_RS05145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALIDE2_RS05160	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ALIDE2_RS05175	COG0489	protein tyrosine kinase activity
ALIDE2_RS05195	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS05205	COG2186	Transcriptional regulator
ALIDE2_RS05225	COG3383	formate dehydrogenase (NAD+) activity
ALIDE2_RS05255	COG3383	formate dehydrogenase (NAD+) activity
ALIDE2_RS05260	COG0437	4 iron, 4 sulfur cluster binding
ALIDE2_RS05280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ALIDE2_RS05285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ALIDE2_RS05310	COG1802	Transcriptional regulator
ALIDE2_RS05310	COG4626	Terminase
ALIDE2_RS05320	COG0066	3-isopropylmalate dehydratase activity
ALIDE2_RS05325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALIDE2_RS05335	COG1193	negative regulation of DNA recombination
ALIDE2_RS05345	COG2003	Belongs to the UPF0758 family
ALIDE2_RS05350	COG1047	Peptidyl-prolyl cis-trans
ALIDE2_RS05355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ALIDE2_RS05360	COG1253	flavin adenine dinucleotide binding
ALIDE2_RS05370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALIDE2_RS05375	COG3781	membrane
ALIDE2_RS05395	COG0582	viral genome integration into host DNA
ALIDE2_RS05430	COG3781	membrane
ALIDE2_RS05445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALIDE2_RS05460	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS05465	COG0180	Tryptophanyl-tRNA synthetase
ALIDE2_RS05470	COG1994	Peptidase M50
ALIDE2_RS05480	COG0009	L-threonylcarbamoyladenylate synthase
ALIDE2_RS05485	COG0613	PHP domain protein
ALIDE2_RS05490	COG0840	transmembrane signaling receptor activity
ALIDE2_RS05495	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ALIDE2_RS05505	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALIDE2_RS05510	COG1136	(ABC) transporter
ALIDE2_RS05525	COG0129	dihydroxy-acid dehydratase activity
ALIDE2_RS05530	COG0129	dihydroxy-acid dehydratase activity
ALIDE2_RS05545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALIDE2_RS05550	COG1802	Transcriptional regulator
ALIDE2_RS05570	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS05590	COG3278	Belongs to the heme-copper respiratory oxidase family
ALIDE2_RS05625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALIDE2_RS05640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALIDE2_RS05660	COG4206	TonB-dependent receptor
ALIDE2_RS05680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALIDE2_RS05685	COG1120	ATPase activity
ALIDE2_RS05695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ALIDE2_RS05700	COG2226	methyltransferase
ALIDE2_RS05705	COG1902	pentaerythritol trinitrate reductase activity
ALIDE2_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS05730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS05740	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS05745	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ALIDE2_RS05750	COG1024	Enoyl-CoA hydratase
ALIDE2_RS05755	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05760	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05770	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS05770	COG1024	Enoyl-CoA hydratase
ALIDE2_RS05775	COG1024	Enoyl-CoA hydratase
ALIDE2_RS05795	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05800	COG1024	Enoyl-CoA hydratase
ALIDE2_RS05805	COG0183	Belongs to the thiolase family
ALIDE2_RS05815	COG0183	Belongs to the thiolase family
ALIDE2_RS05835	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05840	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS05860	COG0436	Aminotransferase
ALIDE2_RS05875	COG1487	ribonuclease activity
ALIDE2_RS05880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ALIDE2_RS05885	COG1763	Mo-molybdopterin cofactor biosynthetic process
ALIDE2_RS05890	COG0303	'Molybdopterin
ALIDE2_RS05900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS05915	COG0314	molybdopterin synthase activity
ALIDE2_RS05920	COG0542	response to heat
ALIDE2_RS05940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ALIDE2_RS05950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALIDE2_RS05955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALIDE2_RS05955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALIDE2_RS05990	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALIDE2_RS06000	COG1492	cobalamin metabolic process
ALIDE2_RS06005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ALIDE2_RS06015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALIDE2_RS06025	COG0154	amidase activity
ALIDE2_RS06030	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS06040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALIDE2_RS06045	COG2900	Belongs to the SlyX family
ALIDE2_RS06050	COG0667	Aldo Keto reductase
ALIDE2_RS06065	COG2346	COG2346, Truncated hemoglobins
ALIDE2_RS06070	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ALIDE2_RS06075	COG1959	2 iron, 2 sulfur cluster binding
ALIDE2_RS06080	COG2766	serine protein kinase
ALIDE2_RS06085	COG2718	Belongs to the UPF0229 family
ALIDE2_RS06090	COG2719	SpoVR family
ALIDE2_RS06100	COG3275	phosphorelay sensor kinase activity
ALIDE2_RS06105	COG0165	Argininosuccinate lyase
ALIDE2_RS06110	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS06120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALIDE2_RS06135	COG0252	asparaginase activity
ALIDE2_RS06140	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS06155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS06165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALIDE2_RS06175	COG5001	Diguanylate cyclase
ALIDE2_RS06175	COG3300	MHYT domain
ALIDE2_RS06180	COG2885	chlorophyll binding
ALIDE2_RS06185	COG1304	FMN binding
ALIDE2_RS06195	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS06200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS06210	COG0583	DNA-binding transcription factor activity
ALIDE2_RS06215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ALIDE2_RS06220	COG0840	transmembrane signaling receptor activity
ALIDE2_RS06225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALIDE2_RS06225	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALIDE2_RS06235	COG3022	response to hydroperoxide
ALIDE2_RS06240	COG1530	ribonuclease E activity
ALIDE2_RS06245	COG0564	pseudouridine synthase activity
ALIDE2_RS06260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ALIDE2_RS06260	COG0616	signal peptide processing
ALIDE2_RS06265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALIDE2_RS06270	COG0424	maF-like protein
ALIDE2_RS06275	COG1399	metal-binding, possibly nucleic acid-binding protein
ALIDE2_RS06280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALIDE2_RS06285	COG0416	fatty acid biosynthetic process
ALIDE2_RS06290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALIDE2_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS06305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALIDE2_RS06310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALIDE2_RS06335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS06340	COG0481	GTPase activity
ALIDE2_RS06355	COG0571	ribonuclease III activity
ALIDE2_RS06360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ALIDE2_RS06365	COG1381	Involved in DNA repair and RecF pathway recombination
ALIDE2_RS06370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALIDE2_RS06375	COG0736	holo-[acyl-carrier-protein] synthase activity
ALIDE2_RS06380	COG1472	Belongs to the glycosyl hydrolase 3 family
ALIDE2_RS06420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALIDE2_RS06425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ALIDE2_RS06430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALIDE2_RS06445	COG0438	transferase activity, transferring glycosyl groups
ALIDE2_RS06450	COG0110	maltose O-acetyltransferase activity
ALIDE2_RS06470	COG0762	integral membrane protein
ALIDE2_RS06475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALIDE2_RS06480	COG0159	tryptophan synthase activity
ALIDE2_RS06485	COG0133	tryptophan synthase activity
ALIDE2_RS06490	COG0135	phosphoribosylanthranilate isomerase activity
ALIDE2_RS06495	COG0101	tRNA pseudouridine synthase activity
ALIDE2_RS06510	COG0473	3-isopropylmalate dehydrogenase activity
ALIDE2_RS06515	COG0066	3-isopropylmalate dehydratase activity
ALIDE2_RS06520	COG5510	response to toxic substance
ALIDE2_RS06525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALIDE2_RS06535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALIDE2_RS06545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ALIDE2_RS06560	COG3154	lipid carrier protein
ALIDE2_RS06565	COG0826	peptidase U32
ALIDE2_RS06570	COG0826	peptidase U32
ALIDE2_RS06575	COG3033	Beta-eliminating lyase
ALIDE2_RS06585	COG0484	heat shock protein binding
ALIDE2_RS06590	COG0443	Heat shock 70 kDa protein
ALIDE2_RS06595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALIDE2_RS06600	COG0360	Binds together with S18 to 16S ribosomal RNA
ALIDE2_RS06605	COG2965	DNA replication, synthesis of RNA primer
ALIDE2_RS06610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ALIDE2_RS06615	COG0359	binds to the 23S rRNA
ALIDE2_RS06625	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS06630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALIDE2_RS06635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALIDE2_RS06660	COG0280	phosphate acetyltransferase
ALIDE2_RS06660	COG0281	malic enzyme
ALIDE2_RS06665	COG2233	PERMEase
ALIDE2_RS06670	COG0840	transmembrane signaling receptor activity
ALIDE2_RS06685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALIDE2_RS06700	COG2186	Transcriptional regulator
ALIDE2_RS06705	COG0583	DNA-binding transcription factor activity
ALIDE2_RS06730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ALIDE2_RS06740	COG0583	DNA-binding transcription factor activity
ALIDE2_RS06745	COG3960	tartronate-semialdehyde synthase activity
ALIDE2_RS06750	COG3622	Belongs to the hyi family
ALIDE2_RS06755	COG2084	Dehydrogenase
ALIDE2_RS06765	COG0405	Gamma-glutamyltransferase
ALIDE2_RS06790	COG0717	Belongs to the dCTP deaminase family
ALIDE2_RS06795	COG2321	neutral zinc metallopeptidase
ALIDE2_RS06800	COG0513	Belongs to the DEAD box helicase family
ALIDE2_RS06815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ALIDE2_RS06835	COG4263	nitrous-oxide reductase activity
ALIDE2_RS06845	COG3245	cytochrome
ALIDE2_RS06855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALIDE2_RS06860	COG2916	Histone family protein nucleoid-structuring protein H-NS
ALIDE2_RS06865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALIDE2_RS06870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALIDE2_RS06880	COG2814	Major facilitator Superfamily
ALIDE2_RS06885	COG3279	Response regulator of the LytR AlgR family
ALIDE2_RS06890	COG2972	Histidine kinase
ALIDE2_RS06905	COG1968	undecaprenyl-diphosphatase activity
ALIDE2_RS06920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS06935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALIDE2_RS06945	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALIDE2_RS06960	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS06975	COG3540	Alkaline phosphatase
ALIDE2_RS06985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALIDE2_RS06990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALIDE2_RS07000	COG0564	pseudouridine synthase activity
ALIDE2_RS07005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALIDE2_RS07010	COG1187	pseudouridine synthase activity
ALIDE2_RS07015	COG0105	UTP biosynthetic process
ALIDE2_RS07020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALIDE2_RS07035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALIDE2_RS07040	COG0124	histidyl-tRNA synthetase
ALIDE2_RS07050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALIDE2_RS07055	COG1160	GTP binding
ALIDE2_RS07060	COG1923	regulation of RNA biosynthetic process
ALIDE2_RS07065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALIDE2_RS07070	COG0330	HflC and HflK could
ALIDE2_RS07075	COG0330	HflC and HflK could
ALIDE2_RS07085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ALIDE2_RS07090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALIDE2_RS07125	COG1187	pseudouridine synthase activity
ALIDE2_RS07155	COG0174	glutamine synthetase
ALIDE2_RS07175	COG0708	Exodeoxyribonuclease III
ALIDE2_RS07185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ALIDE2_RS07190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ALIDE2_RS07200	COG2205	protein histidine kinase activity
ALIDE2_RS07205	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS07210	COG3293	Transposase
ALIDE2_RS07230	COG1360	Flagellar Motor Protein
ALIDE2_RS07250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALIDE2_RS07255	COG0277	FAD linked oxidase domain protein
ALIDE2_RS07265	COG1295	ribonuclease BN
ALIDE2_RS07275	COG1233	COG1233 Phytoene dehydrogenase and related
ALIDE2_RS07280	COG0840	transmembrane signaling receptor activity
ALIDE2_RS07285	COG1562	ergosterol biosynthetic process
ALIDE2_RS07300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS07310	COG0544	peptidyl-prolyl cis-trans isomerase activity
ALIDE2_RS07315	COG0740	serine-type endopeptidase activity
ALIDE2_RS07320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALIDE2_RS07325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALIDE2_RS07340	COG1309	transcriptional regulator
ALIDE2_RS07350	COG2030	dehydratase
ALIDE2_RS07360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07380	COG0778	Nitroreductase
ALIDE2_RS07395	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS07415	COG1902	pentaerythritol trinitrate reductase activity
ALIDE2_RS07415	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALIDE2_RS07440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07465	COG0183	Belongs to the thiolase family
ALIDE2_RS07485	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS07500	COG1024	Enoyl-CoA hydratase
ALIDE2_RS07510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07560	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS07565	COG2030	dehydratase
ALIDE2_RS07575	COG0183	Belongs to the thiolase family
ALIDE2_RS07580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALIDE2_RS07590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS07600	COG0583	DNA-binding transcription factor activity
ALIDE2_RS07605	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS07620	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ALIDE2_RS07645	COG0411	ABC transporter
ALIDE2_RS07665	COG1063	alcohol dehydrogenase
ALIDE2_RS07670	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS07690	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS07695	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS07700	COG1024	Enoyl-CoA hydratase
ALIDE2_RS07720	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS07745	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS07750	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS07785	COG0210	DNA helicase
ALIDE2_RS07810	COG3039	Transposase
ALIDE2_RS07815	COG3039	Transposase
ALIDE2_RS07835	COG2948	multi-organism process
ALIDE2_RS07865	COG3451	type IV secretory pathway VirB4
ALIDE2_RS07875	COG3838	Conjugal transfer protein Trbc
ALIDE2_RS07880	COG4962	Type ii secretion system protein e
ALIDE2_RS07900	COG0583	DNA-binding transcription factor activity
ALIDE2_RS07910	COG1538	Outer membrane efflux protein
ALIDE2_RS07915	COG0842	Transport permease protein
ALIDE2_RS07920	COG0842	Transport permease protein
ALIDE2_RS07925	COG1131	(ABC) transporter
ALIDE2_RS07930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS07935	COG1309	transcriptional regulator
ALIDE2_RS07965	COG1192	Involved in chromosome partitioning
ALIDE2_RS07995	COG5489	Protein of unknown function (DUF736)
ALIDE2_RS08000	COG0640	Transcriptional regulator
ALIDE2_RS08015	COG0798	PFAM Bile acid sodium symporter
ALIDE2_RS08020	COG1393	Belongs to the ArsC family
ALIDE2_RS08025	COG1695	Transcriptional regulator
ALIDE2_RS08040	COG1475	DNA binding
ALIDE2_RS08060	COG2003	Belongs to the UPF0758 family
ALIDE2_RS08100	COG0322	excinuclease ABC activity
ALIDE2_RS08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALIDE2_RS08130	COG1024	Enoyl-CoA hydratase
ALIDE2_RS08135	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ALIDE2_RS08140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS08150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALIDE2_RS08165	COG1024	Enoyl-CoA hydratase
ALIDE2_RS08185	COG2816	NAD+ diphosphatase activity
ALIDE2_RS08190	COG0425	Belongs to the sulfur carrier protein TusA family
ALIDE2_RS08195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ALIDE2_RS08200	COG0525	valine-tRNA ligase activity
ALIDE2_RS08225	COG3278	Belongs to the heme-copper respiratory oxidase family
ALIDE2_RS08245	COG0181	hydroxymethylbilane synthase activity
ALIDE2_RS08250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALIDE2_RS08275	COG3634	alkyl hydroperoxide reductase activity
ALIDE2_RS08280	COG0753	catalase activity
ALIDE2_RS08310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ALIDE2_RS08325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALIDE2_RS08335	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS08350	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS08355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS08365	COG0183	Belongs to the thiolase family
ALIDE2_RS08370	COG1024	Enoyl-CoA hydratase
ALIDE2_RS08395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALIDE2_RS08405	COG0583	DNA-binding transcription factor activity
ALIDE2_RS08410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS08415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALIDE2_RS08430	COG0583	DNA-binding transcription factor activity
ALIDE2_RS08450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ALIDE2_RS08460	COG2188	Transcriptional regulator
ALIDE2_RS08465	COG2986	histidine ammonia-lyase
ALIDE2_RS08475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ALIDE2_RS08480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ALIDE2_RS08490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS08495	COG0765	amino acid transport
ALIDE2_RS08500	COG1126	abc transporter atp-binding protein
ALIDE2_RS08510	COG1228	amidohydrolase
ALIDE2_RS08525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ALIDE2_RS08540	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS08545	COG2721	sulfolactate sulfo-lyase activity
ALIDE2_RS08560	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALIDE2_RS08565	COG0473	3-isopropylmalate dehydrogenase activity
ALIDE2_RS08570	COG0583	DNA-binding transcription factor activity
ALIDE2_RS08595	COG0583	DNA-binding transcription factor activity
ALIDE2_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS08615	COG1309	transcriptional regulator
ALIDE2_RS08625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS08630	COG1131	(ABC) transporter
ALIDE2_RS08635	COG0842	Transport permease protein
ALIDE2_RS08640	COG0842	Transport permease protein
ALIDE2_RS08650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALIDE2_RS08655	COG1611	Belongs to the LOG family
ALIDE2_RS08735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALIDE2_RS08845	COG5002	protein histidine kinase activity
ALIDE2_RS08860	COG1131	(ABC) transporter
ALIDE2_RS08930	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ALIDE2_RS08945	COG0464	growth
ALIDE2_RS08950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALIDE2_RS09010	COG2003	Belongs to the UPF0758 family
ALIDE2_RS09085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALIDE2_RS09095	COG0789	Transcriptional regulator
ALIDE2_RS09100	COG0582	viral genome integration into host DNA
ALIDE2_RS09110	COG4942	peptidase
ALIDE2_RS09145	COG2801	Transposase and inactivated derivatives
ALIDE2_RS09165	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS09170	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS09185	COG1414	Transcriptional regulator
ALIDE2_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS09195	COG0045	succinate-CoA ligase (ADP-forming) activity
ALIDE2_RS09195	COG1042	CoA-binding domain protein
ALIDE2_RS09195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALIDE2_RS09200	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS09205	COG1024	Enoyl-CoA hydratase
ALIDE2_RS09210	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS09215	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS09235	COG2030	dehydratase
ALIDE2_RS09265	COG1024	Enoyl-CoA hydratase
ALIDE2_RS09270	COG2070	2-Nitropropane dioxygenase
ALIDE2_RS09285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS09290	COG0427	acetyl-CoA hydrolase
ALIDE2_RS09300	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS09305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS09310	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS09315	COG2030	dehydratase
ALIDE2_RS09330	COG1024	Enoyl-CoA hydratase
ALIDE2_RS09335	COG1024	Enoyl-CoA hydratase
ALIDE2_RS09345	COG1414	Transcriptional regulator
ALIDE2_RS09355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS09375	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS09380	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS09415	COG0798	PFAM Bile acid sodium symporter
ALIDE2_RS09425	COG0346	lactoylglutathione lyase activity
ALIDE2_RS09430	COG0640	Transcriptional regulator
ALIDE2_RS09605	COG1309	transcriptional regulator
ALIDE2_RS09610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS09620	COG1136	(ABC) transporter
ALIDE2_RS09620	COG0577	efflux transmembrane transporter activity
ALIDE2_RS09660	COG1132	(ABC) transporter
ALIDE2_RS09665	COG1132	(ABC) transporter
ALIDE2_RS09815	COG0582	viral genome integration into host DNA
ALIDE2_RS09825	COG1959	2 iron, 2 sulfur cluster binding
ALIDE2_RS09840	COG0688	phosphatidylethanolamine metabolic process
ALIDE2_RS09845	COG0517	IMP dehydrogenase activity
ALIDE2_RS09845	COG1125	glycine betaine transport
ALIDE2_RS09850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALIDE2_RS09870	COG0776	regulation of translation
ALIDE2_RS09880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALIDE2_RS09885	COG0287	Prephenate dehydrogenase
ALIDE2_RS09890	COG1605	Chorismate mutase
ALIDE2_RS09890	COG0077	Prephenate dehydratase
ALIDE2_RS09895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALIDE2_RS09910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALIDE2_RS09950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ALIDE2_RS10050	COG1475	DNA binding
ALIDE2_RS10100	COG0616	signal peptide processing
ALIDE2_RS10225	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ALIDE2_RS10255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS10275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALIDE2_RS10285	COG0542	response to heat
ALIDE2_RS10290	COG0071	Belongs to the small heat shock protein (HSP20) family
ALIDE2_RS10305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ALIDE2_RS10360	COG2066	Belongs to the glutaminase family
ALIDE2_RS10365	COG1473	amidohydrolase
ALIDE2_RS10410	COG2130	NADP-dependent
ALIDE2_RS10425	COG2814	Major facilitator Superfamily
ALIDE2_RS10430	COG0415	Belongs to the DNA photolyase family
ALIDE2_RS10445	COG0583	DNA-binding transcription factor activity
ALIDE2_RS10470	COG2828	Protein conserved in bacteria
ALIDE2_RS10490	COG1396	sequence-specific DNA binding
ALIDE2_RS10490	COG3800	Transcriptional regulator
ALIDE2_RS10510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ALIDE2_RS10525	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS10560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALIDE2_RS10565	COG1011	Hydrolase
ALIDE2_RS10590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALIDE2_RS10595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALIDE2_RS10600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALIDE2_RS10605	COG0741	lytic transglycosylase activity
ALIDE2_RS10630	COG0557	exoribonuclease II activity
ALIDE2_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS10645	COG2010	Cytochrome c
ALIDE2_RS10645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALIDE2_RS10650	COG3118	belongs to the thioredoxin family
ALIDE2_RS10655	COG0779	Required for maturation of 30S ribosomal subunits
ALIDE2_RS10660	COG0195	Participates in both transcription termination and antitermination
ALIDE2_RS10665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALIDE2_RS10670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALIDE2_RS10675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALIDE2_RS10690	COG1024	Enoyl-CoA hydratase
ALIDE2_RS10710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALIDE2_RS10715	COG2867	negative regulation of translational initiation
ALIDE2_RS10735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALIDE2_RS10735	COG0519	Catalyzes the synthesis of GMP from XMP
ALIDE2_RS10750	COG0582	viral genome integration into host DNA
ALIDE2_RS10805	COG5489	Protein of unknown function (DUF736)
ALIDE2_RS10845	COG1192	Involved in chromosome partitioning
ALIDE2_RS10870	COG2132	Multicopper oxidase
ALIDE2_RS10880	COG5002	protein histidine kinase activity
ALIDE2_RS10890	COG2132	Multicopper oxidase
ALIDE2_RS10930	COG2010	Cytochrome c
ALIDE2_RS10935	COG2217	Heavy metal translocating P-type atpase
ALIDE2_RS10960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS10965	COG0583	DNA-binding transcription factor activity
ALIDE2_RS10985	COG0582	viral genome integration into host DNA
ALIDE2_RS10990	COG0372	Belongs to the citrate synthase family
ALIDE2_RS10995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ALIDE2_RS11000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALIDE2_RS11005	COG1053	succinate dehydrogenase
ALIDE2_RS11010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ALIDE2_RS11015	COG2009	succinate dehydrogenase
ALIDE2_RS11020	COG2188	Transcriptional regulator
ALIDE2_RS11025	COG0039	L-malate dehydrogenase activity
ALIDE2_RS11030	COG4106	trans-aconitate 2-methyltransferase activity
ALIDE2_RS11040	COG1049	propionate catabolic process, 2-methylcitrate cycle
ALIDE2_RS11050	COG0583	DNA-binding transcription factor activity
ALIDE2_RS11055	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS11065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS11070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALIDE2_RS11090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALIDE2_RS11105	COG3608	succinylglutamate desuccinylase aspartoacylase
ALIDE2_RS11105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ALIDE2_RS11135	COG0463	Glycosyl transferase, family 2
ALIDE2_RS11140	COG0826	peptidase U32
ALIDE2_RS11170	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ALIDE2_RS11185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ALIDE2_RS11190	COG1845	cytochrome c oxidase, subunit III
ALIDE2_RS11195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALIDE2_RS11200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALIDE2_RS11205	COG0477	Major facilitator Superfamily
ALIDE2_RS11225	COG0824	Thioesterase
ALIDE2_RS11230	COG0436	Aminotransferase
ALIDE2_RS11235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALIDE2_RS11240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALIDE2_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS11265	COG2918	glutathione biosynthetic process
ALIDE2_RS11270	COG1289	transmembrane transporter activity
ALIDE2_RS11280	COG0251	oxidation-reduction process
ALIDE2_RS11310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ALIDE2_RS11320	COG0564	pseudouridine synthase activity
ALIDE2_RS11375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALIDE2_RS11385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALIDE2_RS11400	COG3384	dioxygenase
ALIDE2_RS11405	COG0400	carboxylic ester hydrolase activity
ALIDE2_RS11415	COG1522	sequence-specific DNA binding
ALIDE2_RS11425	COG0154	amidase activity
ALIDE2_RS11435	COG0583	DNA-binding transcription factor activity
ALIDE2_RS11440	COG2186	Transcriptional regulator
ALIDE2_RS11445	COG2271	Major facilitator Superfamily
ALIDE2_RS11450	COG2084	Dehydrogenase
ALIDE2_RS11455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALIDE2_RS11460	COG3395	kinase activity
ALIDE2_RS11465	COG0235	Class ii aldolase
ALIDE2_RS11470	COG3622	Belongs to the hyi family
ALIDE2_RS11475	COG3228	Belongs to the MtfA family
ALIDE2_RS11480	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALIDE2_RS11505	COG0215	cysteine-tRNA ligase activity
ALIDE2_RS11520	COG0037	tRNA processing
ALIDE2_RS11525	COG0527	aspartate kinase activity
ALIDE2_RS11540	COG1309	transcriptional regulator
ALIDE2_RS11555	COG1136	(ABC) transporter
ALIDE2_RS11560	COG2951	lytic endotransglycosylase activity
ALIDE2_RS11565	COG2925	Exonuclease
ALIDE2_RS11570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ALIDE2_RS11575	COG0628	permease
ALIDE2_RS11585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ALIDE2_RS11595	COG0217	transcriptional regulatory protein
ALIDE2_RS11610	COG1271	oxidase subunit
ALIDE2_RS11615	COG1294	oxidase, subunit
ALIDE2_RS11625	COG1346	cytolysis
ALIDE2_RS11635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALIDE2_RS11640	COG0625	glutathione transferase activity
ALIDE2_RS11645	COG0433	COG0433 Predicted ATPase
ALIDE2_RS11650	COG0217	transcriptional regulatory protein
ALIDE2_RS11655	COG0151	Belongs to the GarS family
ALIDE2_RS11660	COG0408	coproporphyrinogen oxidase activity
ALIDE2_RS11665	COG0799	negative regulation of ribosome biogenesis
ALIDE2_RS11670	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALIDE2_RS11675	COG0424	maF-like protein
ALIDE2_RS11690	COG0535	radical SAM domain protein
ALIDE2_RS11705	COG3391	amine dehydrogenase activity
ALIDE2_RS11710	COG2010	Cytochrome c
ALIDE2_RS11720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALIDE2_RS11720	COG1648	precorrin-2 dehydrogenase activity
ALIDE2_RS11725	COG1530	ribonuclease E activity
ALIDE2_RS11730	COG3706	GGDEF domain
ALIDE2_RS11740	COG0436	Aminotransferase
ALIDE2_RS11745	COG0583	DNA-binding transcription factor activity
ALIDE2_RS11765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALIDE2_RS11785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS11815	COG0589	response to stress
ALIDE2_RS11830	COG0183	Belongs to the thiolase family
ALIDE2_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS11850	COG0545	Peptidyl-prolyl cis-trans isomerase
ALIDE2_RS11855	COG2197	response regulator
ALIDE2_RS11895	COG1595	DNA-templated transcription, initiation
ALIDE2_RS11905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALIDE2_RS11910	COG3048	D-serine ammonia-lyase activity
ALIDE2_RS11915	COG1739	Uncharacterized protein family UPF0029
ALIDE2_RS11935	COG0556	nucleotide-excision repair
ALIDE2_RS11940	COG1959	2 iron, 2 sulfur cluster binding
ALIDE2_RS11945	COG1104	cysteine desulfurase activity
ALIDE2_RS11950	COG0822	iron-sulfur transferase activity
ALIDE2_RS11965	COG0443	Heat shock 70 kDa protein
ALIDE2_RS11970	COG0633	Ferredoxin
ALIDE2_RS11990	COG0579	oxidoreductase
ALIDE2_RS12010	COG0167	dihydroorotate dehydrogenase activity
ALIDE2_RS12015	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALIDE2_RS12030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALIDE2_RS12035	COG4566	intracellular signal transduction
ALIDE2_RS12045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ALIDE2_RS12050	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALIDE2_RS12055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALIDE2_RS12085	COG0583	DNA-binding transcription factor activity
ALIDE2_RS12105	COG4372	Transposase
ALIDE2_RS12115	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS12150	COG0791	NLP P60 protein
ALIDE2_RS12155	COG1113	amino acid transport
ALIDE2_RS12160	COG2814	Major facilitator Superfamily
ALIDE2_RS12170	COG1742	UPF0060 membrane protein
ALIDE2_RS12180	COG1196	nuclear chromosome segregation
ALIDE2_RS12190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALIDE2_RS12195	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALIDE2_RS12235	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALIDE2_RS12240	COG0183	Belongs to the thiolase family
ALIDE2_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS12250	COG0488	(ABC) transporter
ALIDE2_RS12260	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS12265	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS12270	COG0583	DNA-binding transcription factor activity
ALIDE2_RS12275	COG2890	protein-(glutamine-N5) methyltransferase activity
ALIDE2_RS12280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALIDE2_RS12290	COG2171	N-acyltransferase activity
ALIDE2_RS12300	COG2878	Part of a membrane complex involved in electron transport
ALIDE2_RS12325	COG1309	transcriptional regulator
ALIDE2_RS12335	COG1022	Amp-dependent synthetase and ligase
ALIDE2_RS12340	COG1802	Transcriptional regulator
ALIDE2_RS12345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALIDE2_RS12355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS12365	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALIDE2_RS12365	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ALIDE2_RS12370	COG1703	isobutyryl-CoA mutase activity
ALIDE2_RS12375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS12380	COG4770	biotin carboxylase activity
ALIDE2_RS12390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALIDE2_RS12405	COG0642	Histidine kinase
ALIDE2_RS12420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALIDE2_RS12435	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALIDE2_RS12440	COG1538	Outer membrane efflux protein
ALIDE2_RS12455	COG0640	Transcriptional regulator
ALIDE2_RS12475	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS12495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ALIDE2_RS12525	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS12535	COG1024	Enoyl-CoA hydratase
ALIDE2_RS12545	COG1064	alcohol dehydrogenase
ALIDE2_RS12550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS12555	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS12565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS12585	COG4120	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS12595	COG3284	Transcriptional regulator
ALIDE2_RS12620	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALIDE2_RS12625	COG0022	dehydrogenase e1 component
ALIDE2_RS12625	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALIDE2_RS12630	COG0022	dehydrogenase e1 component
ALIDE2_RS12635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ALIDE2_RS12645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALIDE2_RS12655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALIDE2_RS12655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS12665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ALIDE2_RS12670	COG0509	glycine decarboxylation via glycine cleavage system
ALIDE2_RS12675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALIDE2_RS12675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALIDE2_RS12685	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ALIDE2_RS12690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ALIDE2_RS12710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALIDE2_RS12725	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS12745	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALIDE2_RS12750	COG0714	Associated with various cellular activities
ALIDE2_RS12765	COG2951	lytic endotransglycosylase activity
ALIDE2_RS12770	COG3958	Transketolase
ALIDE2_RS12775	COG3959	Transketolase, thiamine diphosphate binding domain
ALIDE2_RS12780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS12790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALIDE2_RS12795	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS12800	COG0583	DNA-binding transcription factor activity
ALIDE2_RS12810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS12815	COG0583	DNA-binding transcription factor activity
ALIDE2_RS12825	COG0683	leucine binding
ALIDE2_RS12835	COG1136	(ABC) transporter
ALIDE2_RS12835	COG0577	efflux transmembrane transporter activity
ALIDE2_RS12840	COG1136	(ABC) transporter
ALIDE2_RS12840	COG0577	efflux transmembrane transporter activity
ALIDE2_RS12845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS12855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALIDE2_RS12860	COG0517	IMP dehydrogenase activity
ALIDE2_RS12860	COG0617	tRNA 3'-terminal CCA addition
ALIDE2_RS12860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ALIDE2_RS12875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS12880	COG1538	Outer membrane efflux protein
ALIDE2_RS12885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALIDE2_RS12895	COG0243	molybdopterin cofactor binding
ALIDE2_RS12900	COG2223	nitrite transmembrane transporter activity
ALIDE2_RS12910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALIDE2_RS12920	COG1607	acyl-coa hydrolase
ALIDE2_RS12925	COG2081	HI0933 family
ALIDE2_RS12945	COG0822	iron-sulfur transferase activity
ALIDE2_RS12950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALIDE2_RS12960	COG0396	ATPase activity
ALIDE2_RS12965	COG0719	Fe-S assembly protein
ALIDE2_RS12970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALIDE2_RS12980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALIDE2_RS13000	COG2755	lipolytic protein G-D-S-L family
ALIDE2_RS13000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ALIDE2_RS13005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALIDE2_RS13005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ALIDE2_RS13015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS13020	COG3473	Maleate cis-trans isomerase
ALIDE2_RS13050	COG0683	leucine binding
ALIDE2_RS13055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS13065	COG2186	Transcriptional regulator
ALIDE2_RS13070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ALIDE2_RS13075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ALIDE2_RS13080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALIDE2_RS13085	COG4208	sulfate ABC transporter
ALIDE2_RS13095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALIDE2_RS13110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ALIDE2_RS13120	COG1464	Belongs to the NlpA lipoprotein family
ALIDE2_RS13125	COG2011	ABC-type metal ion transport system permease component
ALIDE2_RS13130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ALIDE2_RS13140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALIDE2_RS13145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ALIDE2_RS13150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALIDE2_RS13165	COG4149	molybdate abc transporter
ALIDE2_RS13185	COG1120	ATPase activity
ALIDE2_RS13190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALIDE2_RS13195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ALIDE2_RS13205	COG4206	TonB-dependent receptor
ALIDE2_RS13235	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ALIDE2_RS13245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALIDE2_RS13250	COG0254	rRNA binding
ALIDE2_RS13260	COG0534	Mate efflux family protein
ALIDE2_RS13275	COG0704	Plays a role in the regulation of phosphate uptake
ALIDE2_RS13280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALIDE2_RS13285	COG0581	inorganic phosphate transmembrane transporter activity
ALIDE2_RS13290	COG0573	inorganic phosphate transmembrane transporter activity
ALIDE2_RS13295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ALIDE2_RS13325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALIDE2_RS13335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALIDE2_RS13340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ALIDE2_RS13345	COG1534	Rna-binding protein
ALIDE2_RS13360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALIDE2_RS13365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALIDE2_RS13370	COG0505	Belongs to the CarA family
ALIDE2_RS13440	COG2963	transposase activity
ALIDE2_RS13490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALIDE2_RS13500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALIDE2_RS13510	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ALIDE2_RS13530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS13535	COG2226	methyltransferase
ALIDE2_RS13550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS13555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALIDE2_RS13560	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ALIDE2_RS13565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALIDE2_RS13575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ALIDE2_RS13595	COG2326	polyphosphate kinase activity
ALIDE2_RS13615	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS13635	COG3174	membrane
ALIDE2_RS13785	COG1475	DNA binding
ALIDE2_RS13885	COG3620	sequence-specific DNA binding
ALIDE2_RS13955	COG0681	Belongs to the peptidase S26 family
ALIDE2_RS14025	COG0789	Transcriptional regulator
ALIDE2_RS14030	COG0776	regulation of translation
ALIDE2_RS14035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALIDE2_RS14035	COG0072	phenylalanine-tRNA ligase activity
ALIDE2_RS14040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALIDE2_RS14045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ALIDE2_RS14050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALIDE2_RS14055	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ALIDE2_RS14060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALIDE2_RS14110	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ALIDE2_RS14115	COG0670	Belongs to the BI1 family
ALIDE2_RS14135	COG2076	Multidrug Resistance protein
ALIDE2_RS14150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ALIDE2_RS14160	COG5507	3-demethylubiquinone-9 3-methyltransferase
ALIDE2_RS14195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALIDE2_RS14200	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ALIDE2_RS14205	COG4181	ATPase activity
ALIDE2_RS14220	COG0626	cystathionine gamma-synthase activity
ALIDE2_RS14255	COG2133	pyrroloquinoline quinone binding
ALIDE2_RS14260	COG0583	DNA-binding transcription factor activity
ALIDE2_RS14275	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS14300	COG0133	tryptophan synthase activity
ALIDE2_RS14305	COG3171	Protein conserved in bacteria
ALIDE2_RS14310	COG2721	sulfolactate sulfo-lyase activity
ALIDE2_RS14320	COG4948	Mandelate Racemase Muconate Lactonizing
ALIDE2_RS14330	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS14335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS14345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS14350	COG4948	Mandelate Racemase Muconate Lactonizing
ALIDE2_RS14360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALIDE2_RS14365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALIDE2_RS14370	COG1741	Belongs to the pirin family
ALIDE2_RS14375	COG0583	DNA-binding transcription factor activity
ALIDE2_RS14380	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ALIDE2_RS14380	COG0493	'glutamate synthase
ALIDE2_RS14385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALIDE2_RS14390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALIDE2_RS14400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALIDE2_RS14405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS14415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS14420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALIDE2_RS14425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ALIDE2_RS14430	COG1802	Transcriptional regulator
ALIDE2_RS14435	COG0564	pseudouridine synthase activity
ALIDE2_RS14440	COG1042	CoA-binding domain protein
ALIDE2_RS14440	COG0045	succinate-CoA ligase (ADP-forming) activity
ALIDE2_RS14440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALIDE2_RS14460	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS14465	COG3718	enzyme involved in inositol metabolism
ALIDE2_RS14480	COG2169	Transcriptional regulator
ALIDE2_RS14500	COG1619	proteins homologs of microcin C7 resistance protein MccF
ALIDE2_RS14515	COG0826	peptidase U32
ALIDE2_RS14525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALIDE2_RS14530	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ALIDE2_RS14535	COG3047	cAMP biosynthetic process
ALIDE2_RS14540	COG2354	Protein conserved in bacteria
ALIDE2_RS14545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ALIDE2_RS14545	COG0047	phosphoribosylformylglycinamidine synthase activity
ALIDE2_RS14550	COG0024	Methionine aminopeptidase
ALIDE2_RS14560	COG2233	PERMEase
ALIDE2_RS14565	COG0242	peptide deformylase activity
ALIDE2_RS14570	COG2832	Protein of unknown function (DUF454)
ALIDE2_RS14610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALIDE2_RS14615	COG1570	exodeoxyribonuclease VII activity
ALIDE2_RS14620	COG0811	peptide transport
ALIDE2_RS14630	COG1663	tetraacyldisaccharide 4'-kinase activity
ALIDE2_RS14635	COG2835	tetraacyldisaccharide 4'-kinase activity
ALIDE2_RS14640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ALIDE2_RS14645	COG0563	adenylate kinase activity
ALIDE2_RS14650	COG0252	asparaginase activity
ALIDE2_RS14655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ALIDE2_RS14665	COG1643	Atp-dependent helicase
ALIDE2_RS14670	COG0183	Belongs to the thiolase family
ALIDE2_RS14675	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS14680	COG1268	BioY protein
ALIDE2_RS14690	COG1122	ATPase activity
ALIDE2_RS14705	COG0346	lactoylglutathione lyase activity
ALIDE2_RS14740	COG5489	Protein of unknown function (DUF736)
ALIDE2_RS14745	COG1396	sequence-specific DNA binding
ALIDE2_RS14770	COG1192	Involved in chromosome partitioning
ALIDE2_RS14785	COG4959	Type IV secretory pathway protease TraF
ALIDE2_RS14795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALIDE2_RS14805	COG3002	Belongs to the UPF0753 family
ALIDE2_RS14810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALIDE2_RS14815	COG0583	DNA-binding transcription factor activity
ALIDE2_RS14835	COG0583	DNA-binding transcription factor activity
ALIDE2_RS14845	COG1090	epimerase
ALIDE2_RS14855	COG3046	protein related to deoxyribodipyrimidine photolyase
ALIDE2_RS14860	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ALIDE2_RS14865	COG0415	Belongs to the DNA photolyase family
ALIDE2_RS14870	COG3040	lipid binding
ALIDE2_RS14890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALIDE2_RS14925	COG0415	Belongs to the DNA photolyase family
ALIDE2_RS14930	COG0583	DNA-binding transcription factor activity
ALIDE2_RS14945	COG4804	nuclease activity
ALIDE2_RS14960	COG0800	Aldolase
ALIDE2_RS14970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALIDE2_RS14975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS14980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALIDE2_RS14985	COG3265	gluconokinase activity
ALIDE2_RS14990	COG1609	Transcriptional regulator
ALIDE2_RS14995	COG0542	response to heat
ALIDE2_RS15000	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALIDE2_RS15015	COG1199	ATP-dependent helicase activity
ALIDE2_RS15020	COG0631	protein serine/threonine phosphatase activity
ALIDE2_RS15030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ALIDE2_RS15035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALIDE2_RS15040	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALIDE2_RS15045	COG0567	Dehydrogenase, E1 component
ALIDE2_RS15050	COG0628	permease
ALIDE2_RS15075	COG0589	response to stress
ALIDE2_RS15080	COG4172	Belongs to the ABC transporter superfamily
ALIDE2_RS15085	COG4239	(ABC) transporter, permease
ALIDE2_RS15090	COG4174	ABC transporter (Permease)
ALIDE2_RS15115	COG2841	Protein conserved in bacteria
ALIDE2_RS15120	COG1793	dna ligase
ALIDE2_RS15125	COG0861	Integral membrane protein TerC family
ALIDE2_RS15145	COG0583	DNA-binding transcription factor activity
ALIDE2_RS15150	COG0028	Belongs to the TPP enzyme family
ALIDE2_RS15190	COG4372	Transposase
ALIDE2_RS15215	COG5377	YqaJ viral recombinase family
ALIDE2_RS15230	COG0417	DNA replication proofreading
ALIDE2_RS15240	COG3311	Transcriptional regulator
ALIDE2_RS15245	COG0582	viral genome integration into host DNA
ALIDE2_RS15250	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ALIDE2_RS15275	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS15285	COG0410	ABC transporter
ALIDE2_RS15300	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS15310	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS15315	COG0183	Belongs to the thiolase family
ALIDE2_RS15320	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS15335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALIDE2_RS15340	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ALIDE2_RS15345	COG2860	membrane
ALIDE2_RS15350	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ALIDE2_RS15350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS15355	COG0730	response to heat
ALIDE2_RS15375	COG0175	sulfate reduction
ALIDE2_RS15385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALIDE2_RS15390	COG0492	ferredoxin-NADP+ reductase activity
ALIDE2_RS15405	COG0351	phosphomethylpyrimidine kinase
ALIDE2_RS15420	COG2022	thiamine diphosphate biosynthetic process
ALIDE2_RS15435	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS15440	COG1024	Enoyl-CoA hydratase
ALIDE2_RS15460	COG0506	proline dehydrogenase activity
ALIDE2_RS15460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALIDE2_RS15460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ALIDE2_RS15465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALIDE2_RS15470	COG1414	Transcriptional regulator
ALIDE2_RS15480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALIDE2_RS15490	COG0583	DNA-binding transcription factor activity
ALIDE2_RS15515	COG1183	phosphatidylcholine synthase activity
ALIDE2_RS15520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALIDE2_RS15525	COG0440	acetolactate synthase activity
ALIDE2_RS15530	COG0028	Belongs to the TPP enzyme family
ALIDE2_RS15535	COG1595	DNA-templated transcription, initiation
ALIDE2_RS15565	COG0347	Belongs to the P(II) protein family
ALIDE2_RS15585	COG0835	chemotaxis
ALIDE2_RS15590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALIDE2_RS15615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALIDE2_RS15620	COG0746	molybdenum cofactor guanylyltransferase activity
ALIDE2_RS15630	COG0303	'Molybdopterin
ALIDE2_RS15645	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS15655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS15660	COG0583	DNA-binding transcription factor activity
ALIDE2_RS15665	COG0473	3-isopropylmalate dehydrogenase activity
ALIDE2_RS15665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS15670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS15675	COG0436	Aminotransferase
ALIDE2_RS15680	COG0328	RNA-DNA hybrid ribonuclease activity
ALIDE2_RS15685	COG2226	methyltransferase
ALIDE2_RS15690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALIDE2_RS15695	COG1388	LysM domain
ALIDE2_RS15695	COG0741	lytic transglycosylase activity
ALIDE2_RS15705	COG0582	viral genome integration into host DNA
ALIDE2_RS15755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALIDE2_RS15760	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ALIDE2_RS15770	COG0823	Involved in the tonB-independent uptake of proteins
ALIDE2_RS15775	COG1132	(ABC) transporter
ALIDE2_RS15780	COG4770	biotin carboxylase activity
ALIDE2_RS15785	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ALIDE2_RS15790	COG4336	lyase activity
ALIDE2_RS15795	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ALIDE2_RS15800	COG2814	Major facilitator Superfamily
ALIDE2_RS15805	COG1802	Transcriptional regulator
ALIDE2_RS15825	COG0084	hydrolase, TatD family'
ALIDE2_RS15835	COG0470	DNA polymerase III
ALIDE2_RS15840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALIDE2_RS15845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALIDE2_RS15855	COG0590	tRNA wobble adenosine to inosine editing
ALIDE2_RS15860	COG2807	transmembrane transport
ALIDE2_RS15870	COG4566	intracellular signal transduction
ALIDE2_RS15905	COG3618	amidohydrolase
ALIDE2_RS15930	COG1609	Transcriptional regulator
ALIDE2_RS15940	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS15970	COG2183	response to ionizing radiation
ALIDE2_RS15995	COG0259	pyridoxamine-phosphate oxidase activity
ALIDE2_RS16025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALIDE2_RS16030	COG1309	transcriptional regulator
ALIDE2_RS16075	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS16080	COG0765	amino acid transport
ALIDE2_RS16085	COG0765	amino acid transport
ALIDE2_RS16095	COG0183	Belongs to the thiolase family
ALIDE2_RS16100	COG1024	Enoyl-CoA hydratase
ALIDE2_RS16100	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS16110	COG0411	ABC transporter
ALIDE2_RS16120	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS16130	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS16135	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ALIDE2_RS16140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALIDE2_RS16145	COG2917	probably involved in intracellular septation
ALIDE2_RS16155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALIDE2_RS16165	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ALIDE2_RS16175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALIDE2_RS16175	COG2111	Na H antiporter
ALIDE2_RS16180	COG1006	Multisubunit Na H antiporter MnhC subunit
ALIDE2_RS16185	COG0651	ATP synthesis coupled electron transport
ALIDE2_RS16195	COG2212	antiporter activity
ALIDE2_RS16210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ALIDE2_RS16230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS16240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ALIDE2_RS16255	COG1840	ABC-type Fe3 transport system, periplasmic component
ALIDE2_RS16280	COG0582	viral genome integration into host DNA
ALIDE2_RS16345	COG1475	DNA binding
ALIDE2_RS16685	COG2326	polyphosphate kinase activity
ALIDE2_RS16690	COG2217	Heavy metal translocating P-type atpase
ALIDE2_RS16705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ALIDE2_RS16715	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ALIDE2_RS16720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ALIDE2_RS16730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS16775	COG1677	Flagellar hook-basal body complex protein FliE
ALIDE2_RS16790	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALIDE2_RS16800	COG2963	transposase activity
ALIDE2_RS16805	COG2801	Transposase and inactivated derivatives
ALIDE2_RS16815	COG0640	Transcriptional regulator
ALIDE2_RS16820	COG2226	methyltransferase
ALIDE2_RS16845	COG0347	Belongs to the P(II) protein family
ALIDE2_RS16905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALIDE2_RS16920	COG1286	toxin biosynthetic process
ALIDE2_RS16930	COG0285	dihydrofolate synthase activity
ALIDE2_RS16935	COG1393	Belongs to the ArsC family
ALIDE2_RS16945	COG3123	guanosine phosphorylase activity
ALIDE2_RS16950	COG0137	argininosuccinate synthase activity
ALIDE2_RS16955	COG3284	Transcriptional regulator
ALIDE2_RS16960	COG4647	ligase activity
ALIDE2_RS16965	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ALIDE2_RS16970	COG0145	ligase activity
ALIDE2_RS16975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ALIDE2_RS16980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ALIDE2_RS16990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALIDE2_RS16995	COG1666	GTP binding
ALIDE2_RS17000	COG3577	Aspartyl protease
ALIDE2_RS17010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALIDE2_RS17015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ALIDE2_RS17020	COG0667	Aldo Keto reductase
ALIDE2_RS17025	COG3842	ATPase activity
ALIDE2_RS17050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ALIDE2_RS17055	COG0308	aminopeptidase N
ALIDE2_RS17060	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALIDE2_RS17130	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS17135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALIDE2_RS17140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALIDE2_RS17145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALIDE2_RS17150	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALIDE2_RS17155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALIDE2_RS17160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALIDE2_RS17175	COG0750	zinc metalloprotease
ALIDE2_RS17180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ALIDE2_RS17185	COG0575	Belongs to the CDS family
ALIDE2_RS17190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALIDE2_RS17195	COG0233	cytoplasmic translational termination
ALIDE2_RS17200	COG0528	UMP kinase activity
ALIDE2_RS17205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALIDE2_RS17210	COG0052	Belongs to the universal ribosomal protein uS2 family
ALIDE2_RS17250	COG0789	Transcriptional regulator
ALIDE2_RS17280	COG3191	aminopeptidase activity
ALIDE2_RS17290	COG0488	(ABC) transporter
ALIDE2_RS17295	COG0513	Belongs to the DEAD box helicase family
ALIDE2_RS17335	COG0583	DNA-binding transcription factor activity
ALIDE2_RS17340	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS17345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS17350	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS17375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ALIDE2_RS17380	COG0583	DNA-binding transcription factor activity
ALIDE2_RS17410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ALIDE2_RS17415	COG0463	Glycosyl transferase, family 2
ALIDE2_RS17420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALIDE2_RS17425	COG0617	tRNA 3'-terminal CCA addition
ALIDE2_RS17435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALIDE2_RS17440	COG0405	Gamma-glutamyltransferase
ALIDE2_RS17445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALIDE2_RS17455	COG0589	response to stress
ALIDE2_RS17465	COG0728	peptidoglycan biosynthetic process
ALIDE2_RS17470	COG0268	Binds directly to 16S ribosomal RNA
ALIDE2_RS17485	COG4372	Transposase
ALIDE2_RS17540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS17550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALIDE2_RS17555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ALIDE2_RS17570	COG0727	PFAM Uncharacterised protein family (UPF0153)
ALIDE2_RS17595	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ALIDE2_RS17605	COG0601	transmembrane transport
ALIDE2_RS17610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALIDE2_RS17615	COG0444	Belongs to the ABC transporter superfamily
ALIDE2_RS17620	COG4608	Belongs to the ABC transporter superfamily
ALIDE2_RS17625	COG4166	transmembrane transport
ALIDE2_RS17635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ALIDE2_RS17650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS17655	COG0765	amino acid transport
ALIDE2_RS17660	COG1126	abc transporter atp-binding protein
ALIDE2_RS17665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS17685	COG4603	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS17690	COG1129	ABC transporter
ALIDE2_RS17695	COG5002	protein histidine kinase activity
ALIDE2_RS17695	COG5001	Diguanylate cyclase
ALIDE2_RS17695	COG3447	MASE1 domain protein
ALIDE2_RS17725	COG0537	adenosine 5'-monophosphoramidase activity
ALIDE2_RS17730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ALIDE2_RS17735	COG2814	Major facilitator Superfamily
ALIDE2_RS17740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALIDE2_RS17745	COG1136	(ABC) transporter
ALIDE2_RS17750	COG0071	Belongs to the small heat shock protein (HSP20) family
ALIDE2_RS17830	COG1122	ATPase activity
ALIDE2_RS17845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ALIDE2_RS17850	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS17870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ALIDE2_RS17880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS17885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALIDE2_RS17905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALIDE2_RS17910	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ALIDE2_RS17915	COG0724	RNA recognition motif
ALIDE2_RS17930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALIDE2_RS17940	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS17960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALIDE2_RS17965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALIDE2_RS17965	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALIDE2_RS17970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALIDE2_RS17985	COG0560	Phosphoserine phosphatase
ALIDE2_RS18000	COG0412	Dienelactone hydrolase
ALIDE2_RS18005	COG1024	Enoyl-CoA hydratase
ALIDE2_RS18010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS18020	COG0583	DNA-binding transcription factor activity
ALIDE2_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS18060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ALIDE2_RS18070	COG5001	Diguanylate cyclase
ALIDE2_RS18070	COG4251	negative regulation of phosphorylation
ALIDE2_RS18070	COG3706	GGDEF domain
ALIDE2_RS18070	COG2203	Gaf domain
ALIDE2_RS18080	COG0210	DNA helicase
ALIDE2_RS18085	COG0516	GMP reductase activity
ALIDE2_RS18120	COG4771	TonB-dependent receptor
ALIDE2_RS18130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ALIDE2_RS18165	COG2814	Major facilitator Superfamily
ALIDE2_RS18190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALIDE2_RS18195	COG4829	muconolactone delta-isomerase
ALIDE2_RS18210	COG5002	protein histidine kinase activity
ALIDE2_RS18210	COG3447	MASE1 domain protein
ALIDE2_RS18210	COG5001	Diguanylate cyclase
ALIDE2_RS18215	COG0513	Belongs to the DEAD box helicase family
ALIDE2_RS18225	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALIDE2_RS18230	COG0501	Belongs to the peptidase M48B family
ALIDE2_RS18235	COG2154	pterin-4-alpha-carbinolamine dehydratase
ALIDE2_RS18240	COG1162	GTPase activity
ALIDE2_RS18245	COG0659	secondary active sulfate transmembrane transporter activity
ALIDE2_RS18250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALIDE2_RS18255	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ALIDE2_RS18260	COG0494	nUDIX hydrolase
ALIDE2_RS18265	COG0335	large ribosomal subunit rRNA binding
ALIDE2_RS18270	COG0336	Belongs to the RNA methyltransferase TrmD family
ALIDE2_RS18275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALIDE2_RS18280	COG0228	four-way junction DNA binding
ALIDE2_RS18295	COG0306	phosphate transporter
ALIDE2_RS18300	COG1392	Phosphate transport regulator
ALIDE2_RS18330	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS18335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALIDE2_RS18350	COG2963	transposase activity
ALIDE2_RS18365	COG1573	uracil-dna glycosylase
ALIDE2_RS18370	COG1575	Belongs to the MenA family. Type 1 subfamily
ALIDE2_RS18375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALIDE2_RS18380	COG1674	ftsk spoiiie
ALIDE2_RS18385	COG0492	ferredoxin-NADP+ reductase activity
ALIDE2_RS18390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALIDE2_RS18395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALIDE2_RS18400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALIDE2_RS18400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ALIDE2_RS18405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ALIDE2_RS18410	COG3132	Protein of unknown function, DUF480
ALIDE2_RS18415	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS18420	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS18430	COG0196	riboflavin kinase activity
ALIDE2_RS18435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALIDE2_RS18440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALIDE2_RS18445	COG1609	Transcriptional regulator
ALIDE2_RS18450	COG1840	ABC-type Fe3 transport system, periplasmic component
ALIDE2_RS18465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALIDE2_RS18470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ALIDE2_RS18485	COG0583	DNA-binding transcription factor activity
ALIDE2_RS18500	COG0697	spore germination
ALIDE2_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS18530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALIDE2_RS18535	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALIDE2_RS18545	COG0084	hydrolase, TatD family'
ALIDE2_RS18555	COG0640	Transcriptional regulator
ALIDE2_RS18565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS18570	COG0714	Associated with various cellular activities
ALIDE2_RS18580	COG2304	oxidoreductase activity
ALIDE2_RS18585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALIDE2_RS18590	COG4175	Glycine betaine
ALIDE2_RS18595	COG4176	ABC-type proline glycine betaine transport system permease component
ALIDE2_RS18600	COG2113	Glycine betaine
ALIDE2_RS18605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALIDE2_RS18610	COG0114	fumarate hydratase activity
ALIDE2_RS18620	COG3179	chitinase
ALIDE2_RS18625	COG0312	modulator of DNA gyrase
ALIDE2_RS18630	COG3028	Belongs to the UPF0307 family
ALIDE2_RS18635	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALIDE2_RS18640	COG1063	alcohol dehydrogenase
ALIDE2_RS18650	COG1045	serine acetyltransferase
ALIDE2_RS18660	COG0483	inositol monophosphate 1-phosphatase activity
ALIDE2_RS18675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALIDE2_RS18680	COG1201	RNA secondary structure unwinding
ALIDE2_RS18685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALIDE2_RS18690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALIDE2_RS18700	COG1722	exodeoxyribonuclease VII activity
ALIDE2_RS18755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALIDE2_RS18760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ALIDE2_RS18775	COG2850	peptidyl-arginine hydroxylation
ALIDE2_RS18780	COG1047	Peptidyl-prolyl cis-trans
ALIDE2_RS18785	COG0756	dUTP diphosphatase activity
ALIDE2_RS18795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ALIDE2_RS18800	COG0504	CTP synthase activity
ALIDE2_RS18805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALIDE2_RS18815	COG0148	phosphopyruvate hydratase activity
ALIDE2_RS18820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALIDE2_RS18840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS18845	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ALIDE2_RS18855	COG2833	Protein of unknown function (DUF455)
ALIDE2_RS18860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALIDE2_RS18865	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALIDE2_RS18885	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALIDE2_RS18905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALIDE2_RS18910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALIDE2_RS18920	COG0557	exoribonuclease II activity
ALIDE2_RS18925	COG1595	DNA-templated transcription, initiation
ALIDE2_RS18935	COG3474	cytochrome
ALIDE2_RS18945	COG3150	esterase
ALIDE2_RS18950	COG0772	Belongs to the SEDS family
ALIDE2_RS18955	COG0312	modulator of DNA gyrase
ALIDE2_RS18960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALIDE2_RS18970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALIDE2_RS18980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALIDE2_RS18985	COG0511	ligase activity, forming carbon-carbon bonds
ALIDE2_RS18990	COG0439	Biotin carboxylase
ALIDE2_RS18995	COG2264	protein methyltransferase activity
ALIDE2_RS19005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALIDE2_RS19020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALIDE2_RS19020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALIDE2_RS19045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALIDE2_RS19050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALIDE2_RS19055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALIDE2_RS19085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALIDE2_RS19090	COG0012	GTP binding
ALIDE2_RS19100	COG2963	transposase activity
ALIDE2_RS19120	COG4372	Transposase
ALIDE2_RS19135	COG1021	2,3-dihydroxybenzoate-AMP ligase
ALIDE2_RS19140	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS19150	COG2814	Major facilitator Superfamily
ALIDE2_RS19165	COG3246	L-lysine catabolic process to acetate
ALIDE2_RS19170	COG2175	clavaminate synthase activity
ALIDE2_RS19190	COG2197	response regulator
ALIDE2_RS19215	COG2855	membrane
ALIDE2_RS19225	COG1238	metal cluster binding
ALIDE2_RS19230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALIDE2_RS19235	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ALIDE2_RS19240	COG0138	bifunctional purine biosynthesis protein purh
ALIDE2_RS19245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALIDE2_RS19270	COG0840	transmembrane signaling receptor activity
ALIDE2_RS19275	COG2198	Histidine kinase
ALIDE2_RS19275	COG0784	Response regulator, receiver
ALIDE2_RS19275	COG0643	Histidine kinase
ALIDE2_RS19280	COG1678	Uncharacterized ACR, COG1678
ALIDE2_RS19285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALIDE2_RS19290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ALIDE2_RS19295	COG0540	Belongs to the ATCase OTCase family
ALIDE2_RS19310	COG3842	ATPase activity
ALIDE2_RS19315	COG1178	ABC-type Fe3 transport system permease component
ALIDE2_RS19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALIDE2_RS19335	COG0642	Histidine kinase
ALIDE2_RS19345	COG0543	2 iron, 2 sulfur cluster binding
ALIDE2_RS19345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALIDE2_RS19350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALIDE2_RS19375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALIDE2_RS19380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ALIDE2_RS19425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS19430	COG1609	Transcriptional regulator
ALIDE2_RS19435	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS19445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALIDE2_RS19465	COG1414	Transcriptional regulator
ALIDE2_RS19475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ALIDE2_RS19480	COG0183	Belongs to the thiolase family
ALIDE2_RS19495	COG0583	DNA-binding transcription factor activity
ALIDE2_RS19505	COG1473	amidohydrolase
ALIDE2_RS19535	COG0066	3-isopropylmalate dehydratase activity
ALIDE2_RS19540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALIDE2_RS19555	COG0475	glutathione-regulated potassium exporter activity
ALIDE2_RS19555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ALIDE2_RS19560	COG1280	lysine exporter protein (LysE YggA)
ALIDE2_RS19580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALIDE2_RS19585	COG1040	competence protein
ALIDE2_RS19590	COG2226	methyltransferase
ALIDE2_RS19600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ALIDE2_RS19605	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ALIDE2_RS19640	COG0109	protoheme IX farnesyltransferase activity
ALIDE2_RS19645	COG1999	signal sequence binding
ALIDE2_RS19650	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS19655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALIDE2_RS19660	COG4372	Transposase
ALIDE2_RS19680	COG2963	transposase activity
ALIDE2_RS19700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALIDE2_RS19705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALIDE2_RS19725	COG1561	YicC-like family, N-terminal region
ALIDE2_RS19795	COG1222	aaa ATPase
ALIDE2_RS19820	COG0194	GDP metabolic process
ALIDE2_RS19825	COG1758	RNA polymerase activity
ALIDE2_RS19830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALIDE2_RS19850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALIDE2_RS19855	COG1185	polyribonucleotide nucleotidyltransferase activity
ALIDE2_RS19860	COG3321	synthase
ALIDE2_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS19860	COG0604	alcohol dehydrogenase
ALIDE2_RS19865	COG0149	triose-phosphate isomerase activity
ALIDE2_RS19880	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALIDE2_RS19885	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALIDE2_RS19890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALIDE2_RS19895	COG0649	NAD binding
ALIDE2_RS19910	COG1034	ATP synthesis coupled electron transport
ALIDE2_RS19915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ALIDE2_RS19920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALIDE2_RS19930	COG0713	ATP synthesis coupled electron transport
ALIDE2_RS19945	COG1007	ATP synthesis coupled electron transport
ALIDE2_RS19965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ALIDE2_RS19970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ALIDE2_RS19980	COG0586	Pfam SNARE associated Golgi protein
ALIDE2_RS19985	COG0402	S-adenosylhomocysteine deaminase activity
ALIDE2_RS19990	COG2252	PERMEase
ALIDE2_RS20000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ALIDE2_RS20005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ALIDE2_RS20015	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALIDE2_RS20020	COG0802	atpase or kinase
ALIDE2_RS20025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ALIDE2_RS20040	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS20050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALIDE2_RS20055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALIDE2_RS20070	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS20105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ALIDE2_RS20110	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALIDE2_RS20115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALIDE2_RS20120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALIDE2_RS20125	COG0772	Belongs to the SEDS family
ALIDE2_RS20130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALIDE2_RS20135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALIDE2_RS20140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALIDE2_RS20145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALIDE2_RS20160	COG0275	rRNA processing
ALIDE2_RS20165	COG2001	Belongs to the MraZ family
ALIDE2_RS20170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALIDE2_RS20175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALIDE2_RS20190	COG0523	cobalamin synthesis protein
ALIDE2_RS20205	COG2201	protein-glutamate methylesterase activity
ALIDE2_RS20215	COG2202	Pas domain
ALIDE2_RS20215	COG2205	protein histidine kinase activity
ALIDE2_RS20220	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS20225	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS20230	COG0784	Response regulator, receiver
ALIDE2_RS20230	COG3437	response regulator, receiver
ALIDE2_RS20240	COG0784	Response regulator, receiver
ALIDE2_RS20240	COG2205	protein histidine kinase activity
ALIDE2_RS20240	COG5002	protein histidine kinase activity
ALIDE2_RS20250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALIDE2_RS20260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALIDE2_RS20270	COG1187	pseudouridine synthase activity
ALIDE2_RS20290	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ALIDE2_RS20330	COG1846	Transcriptional regulator
ALIDE2_RS20335	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS20340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ALIDE2_RS20350	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS20375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS20385	COG1024	Enoyl-CoA hydratase
ALIDE2_RS20390	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS20395	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS20400	COG0183	Belongs to the thiolase family
ALIDE2_RS20405	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS20405	COG1024	Enoyl-CoA hydratase
ALIDE2_RS20410	COG0583	DNA-binding transcription factor activity
ALIDE2_RS20435	COG0501	Belongs to the peptidase M48B family
ALIDE2_RS20445	COG0418	dihydroorotase activity
ALIDE2_RS20455	COG3189	MarR family transcriptional regulator
ALIDE2_RS20460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ALIDE2_RS20465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALIDE2_RS20470	COG0683	leucine binding
ALIDE2_RS20480	COG0477	Major facilitator Superfamily
ALIDE2_RS20525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALIDE2_RS20545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS20550	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS20590	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ALIDE2_RS20595	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS20600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALIDE2_RS20610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALIDE2_RS20615	COG2203	Gaf domain
ALIDE2_RS20615	COG3706	GGDEF domain
ALIDE2_RS20615	COG5001	Diguanylate cyclase
ALIDE2_RS20615	COG4251	negative regulation of phosphorylation
ALIDE2_RS20620	COG0747	negative chemotaxis
ALIDE2_RS20630	COG5002	protein histidine kinase activity
ALIDE2_RS20630	COG5001	Diguanylate cyclase
ALIDE2_RS20635	COG3012	SEC-C Motif Domain Protein
ALIDE2_RS20685	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS20695	COG0183	Belongs to the thiolase family
ALIDE2_RS20700	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALIDE2_RS20705	COG0288	reversible hydration of carbon dioxide
ALIDE2_RS20710	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS20715	COG0789	Transcriptional regulator
ALIDE2_RS20745	COG0488	(ABC) transporter
ALIDE2_RS20750	COG2201	protein-glutamate methylesterase activity
ALIDE2_RS20755	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALIDE2_RS20760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALIDE2_RS20770	COG2198	Histidine kinase
ALIDE2_RS20770	COG0643	Histidine kinase
ALIDE2_RS20775	COG2201	protein-glutamate methylesterase activity
ALIDE2_RS20790	COG2197	response regulator
ALIDE2_RS20800	COG1987	bacterial-type flagellum assembly
ALIDE2_RS20805	COG1338	Plays a role in the flagellum-specific transport system
ALIDE2_RS20815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALIDE2_RS20855	COG1766	The M ring may be actively involved in energy transduction
ALIDE2_RS20860	COG1677	Flagellar hook-basal body complex protein FliE
ALIDE2_RS20890	COG3754	Rhamnan synthesis protein F
ALIDE2_RS20905	COG0745	RESPONSE REGULATOR receiver
ALIDE2_RS20910	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ALIDE2_RS20935	COG1191	sigma factor activity
ALIDE2_RS20950	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ALIDE2_RS20955	COG1815	bacterial-type flagellum-dependent cell motility
ALIDE2_RS20960	COG1558	bacterial-type flagellum-dependent cell motility
ALIDE2_RS20965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ALIDE2_RS20970	COG1749	Flagellar hook protein flgE
ALIDE2_RS20985	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ALIDE2_RS20990	COG1706	bacterial-type flagellum-dependent cell motility
ALIDE2_RS20995	COG1705	Flagellar rod assembly protein muramidase FlgJ
ALIDE2_RS20995	COG3951	Flagellar rod assembly protein muramidase FlgJ
ALIDE2_RS21005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALIDE2_RS21015	COG2070	2-Nitropropane dioxygenase
ALIDE2_RS21020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALIDE2_RS21030	COG0697	spore germination
ALIDE2_RS21035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ALIDE2_RS21040	COG0384	phenazine biosynthesis protein PhzF
ALIDE2_RS21045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALIDE2_RS21070	COG4251	negative regulation of phosphorylation
ALIDE2_RS21070	COG3706	GGDEF domain
ALIDE2_RS21070	COG2203	Gaf domain
ALIDE2_RS21070	COG5001	Diguanylate cyclase
ALIDE2_RS21095	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS21105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALIDE2_RS21120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALIDE2_RS21125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALIDE2_RS21130	COG0183	Belongs to the thiolase family
ALIDE2_RS21135	COG1024	Enoyl-CoA hydratase
ALIDE2_RS21140	COG1022	Amp-dependent synthetase and ligase
ALIDE2_RS21175	COG0679	Auxin Efflux Carrier
ALIDE2_RS21180	COG0210	DNA helicase
ALIDE2_RS21195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALIDE2_RS21215	COG0179	Fumarylacetoacetate (FAA) hydrolase
ALIDE2_RS21225	COG1802	Transcriptional regulator
ALIDE2_RS21235	COG0589	response to stress
ALIDE2_RS21240	COG0343	queuine tRNA-ribosyltransferase activity
ALIDE2_RS21270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALIDE2_RS21280	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS21280	COG0204	Acyl-transferase
ALIDE2_RS21285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALIDE2_RS21310	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS21315	COG2072	flavoprotein involved in K transport
ALIDE2_RS21340	COG2365	Tyrosine phosphatase family
ALIDE2_RS21345	COG3550	peptidyl-serine autophosphorylation
ALIDE2_RS21365	COG3385	transposase activity
ALIDE2_RS21410	COG1053	succinate dehydrogenase
ALIDE2_RS21455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ALIDE2_RS21455	COG3608	succinylglutamate desuccinylase aspartoacylase
ALIDE2_RS21480	COG0412	Dienelactone hydrolase
ALIDE2_RS21485	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS21490	COG1250	3-hydroxyacyl-CoA dehydrogenase
ALIDE2_RS21490	COG1024	Enoyl-CoA hydratase
ALIDE2_RS21495	COG0183	Belongs to the thiolase family
ALIDE2_RS21500	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS21505	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS21510	COG1129	ABC transporter
ALIDE2_RS21515	COG1172	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS21520	COG1172	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS21525	COG1879	ABC-type sugar transport system periplasmic component
ALIDE2_RS21540	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS21550	COG0582	viral genome integration into host DNA
ALIDE2_RS21555	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS21560	COG0517	IMP dehydrogenase activity
ALIDE2_RS21570	COG0203	ribosomal protein L17
ALIDE2_RS21575	COG0202	RNA polymerase activity
ALIDE2_RS21580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALIDE2_RS21585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALIDE2_RS21590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALIDE2_RS21595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ALIDE2_RS21600	COG0201	protein transport
ALIDE2_RS21605	COG0200	Binds to the 23S rRNA
ALIDE2_RS21610	COG1841	ribosomal large subunit assembly
ALIDE2_RS21615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALIDE2_RS21620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALIDE2_RS21625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALIDE2_RS21630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALIDE2_RS21635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALIDE2_RS21640	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALIDE2_RS21645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALIDE2_RS21650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALIDE2_RS21655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ALIDE2_RS21665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ALIDE2_RS21680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALIDE2_RS21685	COG0783	Belongs to the Dps family
ALIDE2_RS21695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALIDE2_RS21705	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALIDE2_RS21725	COG0583	DNA-binding transcription factor activity
ALIDE2_RS21730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ALIDE2_RS21735	COG0134	indole-3-glycerol-phosphate synthase activity
ALIDE2_RS21740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALIDE2_RS21785	COG0840	transmembrane signaling receptor activity
ALIDE2_RS21795	COG0546	phosphoglycolate phosphatase activity
ALIDE2_RS21805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ALIDE2_RS21810	COG2967	ApaG domain
ALIDE2_RS21825	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ALIDE2_RS21845	COG4970	Tfp pilus assembly protein FimT
ALIDE2_RS21870	COG1309	transcriptional regulator
ALIDE2_RS21875	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALIDE2_RS21880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ALIDE2_RS21885	COG1538	Outer membrane efflux protein
ALIDE2_RS21890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS21895	COG0842	Transport permease protein
ALIDE2_RS21895	COG1129	ABC transporter
ALIDE2_RS21900	COG0842	Transport permease protein
ALIDE2_RS21910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALIDE2_RS21915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALIDE2_RS21920	COG1546	Belongs to the CinA family
ALIDE2_RS21925	COG0840	transmembrane signaling receptor activity
ALIDE2_RS21945	COG3012	SEC-C Motif Domain Protein
ALIDE2_RS21945	COG3318	Belongs to the UPF0149 family
ALIDE2_RS21970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ALIDE2_RS21975	COG1137	ATPase activity
ALIDE2_RS21985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALIDE2_RS21995	COG0018	arginyl-trna synthetase
ALIDE2_RS22010	COG1301	dicarboxylic acid transport
ALIDE2_RS22015	COG4191	Histidine kinase
ALIDE2_RS22030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ALIDE2_RS22035	COG1942	4-Oxalocrotonate Tautomerase
ALIDE2_RS22045	COG0121	glutamine amidotransferase
ALIDE2_RS22075	COG0189	ligase activity
ALIDE2_RS22080	COG3135	benzoate transporter
ALIDE2_RS22085	COG3158	transport of potassium into the cell
ALIDE2_RS22095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALIDE2_RS22105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALIDE2_RS22130	COG1466	dna polymerase III delta subunit
ALIDE2_RS22140	COG0495	leucyl-tRNA aminoacylation
ALIDE2_RS22145	COG0668	transmembrane transport
ALIDE2_RS22150	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS22155	COG4772	TonB-dependent receptor
ALIDE2_RS22160	COG3284	Transcriptional regulator
ALIDE2_RS22170	COG2200	EAL domain
ALIDE2_RS22170	COG2199	diguanylate cyclase activity
ALIDE2_RS22170	COG2202	Pas domain
ALIDE2_RS22185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALIDE2_RS22190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALIDE2_RS22195	COG0735	belongs to the Fur family
ALIDE2_RS22200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ALIDE2_RS22210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ALIDE2_RS22215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALIDE2_RS22220	COG3118	belongs to the thioredoxin family
ALIDE2_RS22230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALIDE2_RS22235	COG0009	L-threonylcarbamoyladenylate synthase
ALIDE2_RS22255	COG2027	D-alanyl-D-alanine carboxypeptidase
ALIDE2_RS22275	COG0598	Magnesium transport protein CorA
ALIDE2_RS22295	COG0318	PFAM AMP-dependent synthetase and ligase
ALIDE2_RS22300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ALIDE2_RS22305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ALIDE2_RS22320	COG0469	pyruvate kinase activity
ALIDE2_RS22325	COG0006	proline dipeptidase activity
ALIDE2_RS22330	COG1024	Enoyl-CoA hydratase
ALIDE2_RS22355	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS22360	COG0583	DNA-binding transcription factor activity
ALIDE2_RS22365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ALIDE2_RS22370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALIDE2_RS22375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALIDE2_RS22385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ALIDE2_RS22390	COG0583	DNA-binding transcription factor activity
ALIDE2_RS22435	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS22450	COG0583	DNA-binding transcription factor activity
ALIDE2_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS22470	COG3148	PFAM DTW domain containing protein
ALIDE2_RS22495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALIDE2_RS22495	COG1042	CoA-binding domain protein
ALIDE2_RS22495	COG0045	succinate-CoA ligase (ADP-forming) activity
ALIDE2_RS22500	COG0625	glutathione transferase activity
ALIDE2_RS22505	COG1028	Short-chain dehydrogenase reductase Sdr
ALIDE2_RS22515	COG0551	DNA topoisomerase type I activity
ALIDE2_RS22515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ALIDE2_RS22535	COG0604	alcohol dehydrogenase
ALIDE2_RS22545	COG2030	dehydratase
ALIDE2_RS22555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALIDE2_RS22560	COG1846	Transcriptional regulator
ALIDE2_RS22580	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS22585	COG0642	Histidine kinase
ALIDE2_RS22600	COG1178	ABC-type Fe3 transport system permease component
ALIDE2_RS22605	COG3842	ATPase activity
ALIDE2_RS22610	COG1840	ABC-type Fe3 transport system, periplasmic component
ALIDE2_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
ALIDE2_RS22635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS22640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ALIDE2_RS22645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS22660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ALIDE2_RS22665	COG2137	regulation of response to DNA damage stimulus
ALIDE2_RS22675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALIDE2_RS22680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALIDE2_RS22685	COG1862	Preprotein translocase
ALIDE2_RS22695	COG1522	sequence-specific DNA binding
ALIDE2_RS22700	COG2814	Major facilitator Superfamily
ALIDE2_RS22705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ALIDE2_RS22715	COG4566	intracellular signal transduction
ALIDE2_RS22735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ALIDE2_RS22740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALIDE2_RS22750	COG0625	glutathione transferase activity
ALIDE2_RS22775	COG0861	Integral membrane protein TerC family
ALIDE2_RS22785	COG0583	DNA-binding transcription factor activity
ALIDE2_RS22795	COG1950	PFAM Membrane protein of
ALIDE2_RS22800	COG4783	chaperone-mediated protein folding
ALIDE2_RS22805	COG0315	cyclic pyranopterin monophosphate synthase activity
ALIDE2_RS22815	COG1234	tRNA 3'-trailer cleavage
ALIDE2_RS22820	COG1716	ATPase activity
ALIDE2_RS22830	COG0861	Integral membrane protein TerC family
ALIDE2_RS22835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALIDE2_RS22840	COG0045	succinate-CoA ligase (ADP-forming) activity
ALIDE2_RS22845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALIDE2_RS22850	COG0758	DNA mediated transformation
ALIDE2_RS22860	COG0242	peptide deformylase activity
ALIDE2_RS22870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALIDE2_RS22885	COG0126	phosphoglycerate kinase activity
ALIDE2_RS22900	COG0697	spore germination
ALIDE2_RS22905	COG0284	orotidine-5'-phosphate decarboxylase activity
ALIDE2_RS22935	COG2814	Major facilitator Superfamily
ALIDE2_RS22940	COG0629	single-stranded DNA binding
ALIDE2_RS22945	COG1620	l-lactate permease
ALIDE2_RS22950	COG0482	sulfurtransferase activity
ALIDE2_RS22955	COG0583	DNA-binding transcription factor activity
ALIDE2_RS22960	COG2828	Protein conserved in bacteria
ALIDE2_RS22970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ALIDE2_RS22980	COG3976	FMN-binding domain protein
ALIDE2_RS22980	COG1053	succinate dehydrogenase
ALIDE2_RS23000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ALIDE2_RS23015	COG0439	Biotin carboxylase
ALIDE2_RS23020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ALIDE2_RS23055	COG3181	Tripartite tricarboxylate transporter family receptor
ALIDE2_RS23060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS23070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALIDE2_RS23080	COG1280	lysine exporter protein (LysE YggA)
ALIDE2_RS23105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALIDE2_RS23110	COG3038	cytochrome b561
ALIDE2_RS23130	COG1477	protein flavinylation
ALIDE2_RS23145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ALIDE2_RS23155	COG2070	2-Nitropropane dioxygenase
ALIDE2_RS23165	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS23170	COG1414	Transcriptional regulator
ALIDE2_RS23175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS23185	COG1960	acyl-CoA dehydrogenase activity
ALIDE2_RS23200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ALIDE2_RS23230	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ALIDE2_RS23275	COG3706	GGDEF domain
ALIDE2_RS23280	COG1802	Transcriptional regulator
ALIDE2_RS23290	COG0559	Belongs to the binding-protein-dependent transport system permease family
ALIDE2_RS23295	COG4177	L-phenylalanine transmembrane transporter activity
ALIDE2_RS23335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALIDE2_RS23340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALIDE2_RS23345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ALIDE2_RS23355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALIDE2_RS23370	COG1196	nuclear chromosome segregation
ALIDE2_RS23385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALIDE2_RS23390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALIDE2_RS23395	COG2119	membrane
ALIDE2_RS23400	COG0724	RNA recognition motif
ALIDE2_RS23405	COG0724	RNA recognition motif
ALIDE2_RS23410	COG0300	oxidoreductase activity
ALIDE2_RS23420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALIDE2_RS23435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ALIDE2_RS23450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALIDE2_RS23455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALIDE2_RS23460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ALIDE2_RS23490	COG0601	transmembrane transport
ALIDE2_RS23500	COG4172	Belongs to the ABC transporter superfamily
ALIDE2_RS23505	COG1446	asparaginase
ALIDE2_RS23525	COG0747	negative chemotaxis
ALIDE2_RS23530	COG0706	membrane insertase activity
ALIDE2_RS23535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ALIDE2_RS23540	COG0594	ribonuclease P activity
ALIDE2_RS23545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ALIDE2_RS23715	COG5002	protein histidine kinase activity
ALIDE2_RS23715	COG3447	MASE1 domain protein
ALIDE2_RS23715	COG5001	Diguanylate cyclase
ALIDE2_RS23730	COG2203	Gaf domain
ALIDE2_RS23730	COG3706	GGDEF domain
ALIDE2_RS23730	COG4251	negative regulation of phosphorylation
ALIDE2_RS23730	COG5001	Diguanylate cyclase
ALIDE2_RS23915	COG0445	tRNA wobble uridine modification
ALIDE2_RS23930	COG0445	tRNA wobble uridine modification
ALIDE2_RS24050	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ALIDE2_RS24105	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS24110	COG4974	Belongs to the 'phage' integrase family
ALIDE2_RS24115	COG1804	L-carnitine dehydratase bile acid-inducible protein F