locus-tag	class	description
GI364_RS00010	COG0592	DNA-directed DNA polymerase activity
GI364_RS00015	COG2501	S4 domain
GI364_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GI364_RS00030	COG0187	DNA topoisomerase II activity
GI364_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI364_RS00040	COG0589	response to stress
GI364_RS00065	COG0517	IMP dehydrogenase activity
GI364_RS00065	COG0516	GMP reductase activity
GI364_RS00070	COG1686	Belongs to the peptidase S11 family
GI364_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GI364_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GI364_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GI364_RS00110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS00140	COG1725	Transcriptional regulator
GI364_RS00150	COG1131	(ABC) transporter
GI364_RS00175	COG3842	ATPase activity
GI364_RS00180	COG1653	transport
GI364_RS00190	COG0395	ABC-type sugar transport system, permease component
GI364_RS00200	COG3708	Transcriptional regulator
GI364_RS00200	COG2207	Transcriptional regulator
GI364_RS00225	COG3842	ATPase activity
GI364_RS00230	COG4208	sulfate ABC transporter
GI364_RS00245	COG0840	transmembrane signaling receptor activity
GI364_RS00265	COG1131	(ABC) transporter
GI364_RS00280	COG0006	proline dipeptidase activity
GI364_RS00295	COG0393	Putative heavy-metal-binding
GI364_RS00300	COG0393	Putative heavy-metal-binding
GI364_RS00305	COG1842	Phage shock protein A
GI364_RS00320	COG0488	(ABC) transporter
GI364_RS00325	COG1234	tRNA 3'-trailer cleavage
GI364_RS00330	COG0561	phosphatase activity
GI364_RS00345	COG3842	ATPase activity
GI364_RS00365	COG3328	transposase activity
GI364_RS00370	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS00375	COG2427	Protein of unknown function (DUF1641)
GI364_RS00395	COG1595	DNA-templated transcription, initiation
GI364_RS00405	COG2508	Transcriptional regulator
GI364_RS00410	COG0006	proline dipeptidase activity
GI364_RS00420	COG1473	amidohydrolase
GI364_RS00425	COG0460	homoserine dehydrogenase
GI364_RS00430	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS00435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GI364_RS00440	COG2423	ornithine cyclodeaminase activity
GI364_RS00450	COG0765	amino acid transport
GI364_RS00455	COG1126	abc transporter atp-binding protein
GI364_RS00460	COG0765	amino acid transport
GI364_RS00470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_RS00500	COG4499	WXG100 protein secretion system (Wss), protein YukC
GI364_RS00500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_RS00505	COG0768	penicillin binding
GI364_RS00510	COG0463	Glycosyl transferase, family 2
GI364_RS00520	COG5002	protein histidine kinase activity
GI364_RS00525	COG2814	Major facilitator Superfamily
GI364_RS00540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GI364_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS00575	COG3069	C4-dicarboxylate transmembrane transporter activity
GI364_RS00580	COG0463	Glycosyl transferase, family 2
GI364_RS00585	COG2246	polysaccharide biosynthetic process
GI364_RS00600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI364_RS00610	COG1682	transport, permease protein
GI364_RS00655	COG0427	acetyl-CoA hydrolase
GI364_RS00660	COG0506	proline dehydrogenase activity
GI364_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS00700	COG0667	Aldo Keto reductase
GI364_RS00705	COG1595	DNA-templated transcription, initiation
GI364_RS00715	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS00720	COG1960	acyl-CoA dehydrogenase activity
GI364_RS00730	COG0789	Transcriptional regulator
GI364_RS00735	COG3279	Response regulator of the LytR AlgR family
GI364_RS00740	COG0427	acetyl-CoA hydrolase
GI364_RS00770	COG1131	(ABC) transporter
GI364_RS00780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_RS00795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI364_RS00805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GI364_RS00820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GI364_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS00830	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS00840	COG5002	protein histidine kinase activity
GI364_RS00845	COG0745	RESPONSE REGULATOR receiver
GI364_RS00860	COG2271	Major facilitator Superfamily
GI364_RS00875	COG1027	Aspartate ammonia-lyase
GI364_RS00880	COG1929	Belongs to the glycerate kinase type-1 family
GI364_RS00885	COG0531	amino acid
GI364_RS00900	COG2267	carboxylic ester hydrolase activity
GI364_RS00915	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GI364_RS00930	COG0564	pseudouridine synthase activity
GI364_RS00945	COG4585	Histidine kinase
GI364_RS00950	COG2197	response regulator
GI364_RS00985	COG0456	acetyltransferase
GI364_RS01005	COG0655	NAD(P)H dehydrogenase (quinone) activity
GI364_RS01030	COG1309	transcriptional regulator
GI364_RS01040	COG0840	transmembrane signaling receptor activity
GI364_RS01050	COG0444	Belongs to the ABC transporter superfamily
GI364_RS01055	COG4608	Belongs to the ABC transporter superfamily
GI364_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS01070	COG0601	transmembrane transport
GI364_RS01085	COG0395	ABC-type sugar transport system, permease component
GI364_RS01090	COG1175	transmembrane transport
GI364_RS01100	COG0768	penicillin binding
GI364_RS01110	COG0514	ATP-dependent DNA helicase (RecQ)
GI364_RS01115	COG0673	inositol 2-dehydrogenase activity
GI364_RS01130	COG0747	negative chemotaxis
GI364_RS01145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_RS01155	COG1960	acyl-CoA dehydrogenase activity
GI364_RS01165	COG1476	TRANSCRIPTIONal
GI364_RS01200	COG4715	Zinc finger, swim domain protein
GI364_RS01215	COG2249	NAD(P)H dehydrogenase (quinone) activity
GI364_RS01220	COG0527	aspartate kinase activity
GI364_RS01225	COG4492	Belongs to the UPF0735 family
GI364_RS01230	COG0527	aspartate kinase activity
GI364_RS01240	COG3876	Protein conserved in bacteria
GI364_RS01250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_RS01255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GI364_RS01260	COG2971	BadF BadG BcrA BcrD
GI364_RS01270	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_RS01275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI364_RS01285	COG4166	transmembrane transport
GI364_RS01295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS01300	COG0444	Belongs to the ABC transporter superfamily
GI364_RS01305	COG4608	Belongs to the ABC transporter superfamily
GI364_RS01310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GI364_RS01320	COG1472	Belongs to the glycosyl hydrolase 3 family
GI364_RS01330	COG0154	amidase activity
GI364_RS01350	COG1091	dTDP-4-dehydrorhamnose reductase activity
GI364_RS01365	COG0529	Catalyzes the synthesis of activated sulfate
GI364_RS01370	COG0471	metal ion transport
GI364_RS01370	COG3273	potassium ion transport
GI364_RS01375	COG2046	Belongs to the sulfate adenylyltransferase family
GI364_RS01405	COG1215	transferase activity, transferring glycosyl groups
GI364_RS01425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GI364_RS01435	COG0582	viral genome integration into host DNA
GI364_RS01460	COG2318	DinB family
GI364_RS01470	COG2378	regulation of single-species biofilm formation
GI364_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS01490	COG1442	glycosyl transferase family 8
GI364_RS01490	COG1216	Glycosyl transferase, family 2
GI364_RS01495	COG1316	TRANSCRIPTIONal
GI364_RS01535	COG1940	carbohydrate kinase activity
GI364_RS01545	COG0745	RESPONSE REGULATOR receiver
GI364_RS01550	COG2205	protein histidine kinase activity
GI364_RS01555	COG1131	(ABC) transporter
GI364_RS01570	COG0706	membrane insertase activity
GI364_RS01600	COG0583	DNA-binding transcription factor activity
GI364_RS01610	COG2814	Major facilitator Superfamily
GI364_RS01620	COG1940	carbohydrate kinase activity
GI364_RS01630	COG1175	transmembrane transport
GI364_RS01635	COG0395	ABC-type sugar transport system, permease component
GI364_RS01640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_RS01650	COG0363	glucosamine-6-phosphate deaminase activity
GI364_RS01685	COG2199	diguanylate cyclase activity
GI364_RS01685	COG2200	EAL domain
GI364_RS01690	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_RS01715	COG1132	(ABC) transporter
GI364_RS01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_RS01765	COG2201	protein-glutamate methylesterase activity
GI364_RS01770	COG2198	Histidine kinase
GI364_RS01770	COG0643	Histidine kinase
GI364_RS01785	COG2188	Transcriptional regulator
GI364_RS01805	COG0010	Belongs to the arginase family
GI364_RS01810	COG1228	amidohydrolase
GI364_RS01820	COG2207	Transcriptional regulator
GI364_RS01825	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GI364_RS01830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_RS01845	COG1131	(ABC) transporter
GI364_RS01850	COG2755	lipolytic protein G-D-S-L family
GI364_RS01850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GI364_RS01860	COG1510	regulation of RNA biosynthetic process
GI364_RS01865	COG2113	Glycine betaine
GI364_RS01875	COG3191	aminopeptidase activity
GI364_RS01890	COG1177	transmembrane transport
GI364_RS01895	COG1840	ABC-type Fe3 transport system, periplasmic component
GI364_RS01900	COG3842	ATPase activity
GI364_RS01905	COG0583	DNA-binding transcription factor activity
GI364_RS01910	COG2814	Major facilitator Superfamily
GI364_RS01915	COG1388	LysM domain
GI364_RS01915	COG0791	NLP P60 protein
GI364_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI364_RS01925	COG0765	amino acid transport
GI364_RS01930	COG1126	abc transporter atp-binding protein
GI364_RS01950	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_RS01955	COG3153	acetyltransferase
GI364_RS01955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_RS01960	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS01965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_RS01970	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS01985	COG1917	Cupin 2, conserved barrel domain protein
GI364_RS01990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_RS01995	COG0456	acetyltransferase
GI364_RS02010	COG4990	cell redox homeostasis
GI364_RS02015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_RS02020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GI364_RS02060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_RS02075	COG0662	Cupin 2, conserved barrel domain protein
GI364_RS02075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GI364_RS02085	COG5002	protein histidine kinase activity
GI364_RS02105	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_RS02115	COG4946	Tricorn protease homolog
GI364_RS02115	COG1506	peptidase
GI364_RS02115	COG0823	Involved in the tonB-independent uptake of proteins
GI364_RS02125	COG2210	Belongs to the sulfur carrier protein TusA family
GI364_RS02130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS02135	COG0730	response to heat
GI364_RS02140	COG1309	transcriptional regulator
GI364_RS02145	COG1960	acyl-CoA dehydrogenase activity
GI364_RS02150	COG0439	Biotin carboxylase
GI364_RS02155	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GI364_RS02160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI364_RS02165	COG0277	FAD linked oxidase domain protein
GI364_RS02185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS02200	COG1346	cytolysis
GI364_RS02205	COG1380	Effector of murein hydrolase LrgA
GI364_RS02210	COG0302	gtp cyclohydrolase
GI364_RS02215	COG0697	spore germination
GI364_RS02225	COG1511	domain protein
GI364_RS02230	COG1122	ATPase activity
GI364_RS02240	COG1802	Transcriptional regulator
GI364_RS02255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS02265	COG2059	Chromate
GI364_RS02270	COG2059	Chromate
GI364_RS02275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GI364_RS02285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_RS02285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_RS02310	COG0583	DNA-binding transcription factor activity
GI364_RS02315	COG0038	chloride channel
GI364_RS02320	COG1615	UPF0182 protein
GI364_RS02330	COG0367	asparagine synthase
GI364_RS02355	COG3852	Histidine kinase
GI364_RS02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GI364_RS02365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GI364_RS02370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GI364_RS02385	COG2244	polysaccharide biosynthetic process
GI364_RS02405	COG1982	Orn Lys Arg decarboxylase major
GI364_RS02410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GI364_RS02415	COG3870	Protein conserved in bacteria
GI364_RS02425	COG1774	PSP1 C-terminal conserved region
GI364_RS02430	COG4467	Involved in initiation control of chromosome replication
GI364_RS02435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GI364_RS02440	COG2002	toxin-antitoxin pair type II binding
GI364_RS02450	COG0084	hydrolase, TatD family'
GI364_RS02455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GI364_RS02460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GI364_RS02465	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GI364_RS02480	COG4466	Protein conserved in bacteria
GI364_RS02490	COG4242	Belongs to the peptidase S51 family
GI364_RS02495	COG0189	ligase activity
GI364_RS02495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GI364_RS02500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GI364_RS02505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_RS02510	COG0251	oxidation-reduction process
GI364_RS02515	COG2088	sporulation resulting in formation of a cellular spore
GI364_RS02520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GI364_RS02525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GI364_RS02530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GI364_RS02535	COG0193	aminoacyl-tRNA hydrolase activity
GI364_RS02545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GI364_RS02555	COG2002	toxin-antitoxin pair type II binding
GI364_RS02560	COG2244	polysaccharide biosynthetic process
GI364_RS02565	COG3956	TIGRFAM MazG family protein
GI364_RS02575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GI364_RS02595	COG1098	S1 RNA binding domain
GI364_RS02615	COG0717	Belongs to the dCTP deaminase family
GI364_RS02620	COG2208	phosphoserine phosphatase activity
GI364_RS02625	COG2304	oxidoreductase activity
GI364_RS02630	COG0515	serine threonine protein kinase
GI364_RS02635	COG0037	tRNA processing
GI364_RS02645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI364_RS02655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GI364_RS02660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GI364_RS02665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GI364_RS02670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GI364_RS02675	COG1396	sequence-specific DNA binding
GI364_RS02680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GI364_RS02685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GI364_RS02710	COG1653	transport
GI364_RS02725	COG0366	Alpha amylase catalytic
GI364_RS02730	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_RS02765	COG2197	response regulator
GI364_RS02810	COG2884	Cell division ATP-binding protein ftsE
GI364_RS02815	COG2177	Part of the ABC transporter FtsEX involved in
GI364_RS02820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS02825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GI364_RS02830	COG1360	Flagellar Motor Protein
GI364_RS02835	COG0556	nucleotide-excision repair
GI364_RS02840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GI364_RS02845	COG2508	Transcriptional regulator
GI364_RS02850	COG3842	ATPase activity
GI364_RS02855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GI364_RS02865	COG0018	arginyl-trna synthetase
GI364_RS02880	COG1051	belongs to the nudix hydrolase family
GI364_RS02885	COG1940	carbohydrate kinase activity
GI364_RS02890	COG1660	Displays ATPase and GTPase activities
GI364_RS02895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GI364_RS02900	COG1481	regulation of sporulation
GI364_RS02905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GI364_RS02915	COG2197	response regulator
GI364_RS02920	COG4585	Histidine kinase
GI364_RS02925	COG0842	Transport permease protein
GI364_RS02930	COG0842	Transport permease protein
GI364_RS02935	COG1131	(ABC) transporter
GI364_RS02950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS02955	COG1194	a g-specific adenine glycosylase
GI364_RS02960	COG0670	Belongs to the BI1 family
GI364_RS02965	COG0495	leucyl-tRNA aminoacylation
GI364_RS02980	COG2211	Major facilitator Superfamily
GI364_RS03005	COG1205	dead DEAH box helicase
GI364_RS03005	COG1111	helicase
GI364_RS03010	COG3359	exonuclease
GI364_RS03020	COG3385	transposase activity
GI364_RS03025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GI364_RS03030	COG4493	Belongs to the UPF0637 family
GI364_RS03040	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS03050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GI364_RS03065	COG0697	spore germination
GI364_RS03080	COG1396	sequence-specific DNA binding
GI364_RS03225	COG2105	PFAM AIG2 family protein
GI364_RS03225	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GI364_RS03245	COG1988	membrane-bound metal-dependent
GI364_RS03290	COG2226	methyltransferase
GI364_RS03315	COG2894	cell division
GI364_RS03365	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GI364_RS03395	COG2200	EAL domain
GI364_RS03395	COG2202	Pas domain
GI364_RS03395	COG2199	diguanylate cyclase activity
GI364_RS03425	COG3706	GGDEF domain
GI364_RS03435	COG2203	Gaf domain
GI364_RS03435	COG3706	GGDEF domain
GI364_RS03435	COG4251	negative regulation of phosphorylation
GI364_RS03435	COG5001	Diguanylate cyclase
GI364_RS03455	COG0534	Mate efflux family protein
GI364_RS03465	COG4251	negative regulation of phosphorylation
GI364_RS03465	COG3706	GGDEF domain
GI364_RS03465	COG2203	Gaf domain
GI364_RS03465	COG5001	Diguanylate cyclase
GI364_RS03515	COG0697	spore germination
GI364_RS03540	COG4974	Belongs to the 'phage' integrase family
GI364_RS03570	COG0531	amino acid
GI364_RS03575	COG0582	viral genome integration into host DNA
GI364_RS03595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS03610	COG0697	spore germination
GI364_RS03625	COG0328	RNA-DNA hybrid ribonuclease activity
GI364_RS03630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GI364_RS03635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GI364_RS03645	COG0473	3-isopropylmalate dehydrogenase activity
GI364_RS03655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GI364_RS03660	COG0546	phosphoglycolate phosphatase activity
GI364_RS03675	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_RS03695	COG2766	serine protein kinase
GI364_RS03705	COG0730	response to heat
GI364_RS03710	COG0730	response to heat
GI364_RS03730	COG2718	Belongs to the UPF0229 family
GI364_RS03740	COG1113	amino acid transport
GI364_RS03745	COG3033	Beta-eliminating lyase
GI364_RS03785	COG1396	sequence-specific DNA binding
GI364_RS03935	COG2105	PFAM AIG2 family protein
GI364_RS03950	COG0697	spore germination
GI364_RS03990	COG1988	membrane-bound metal-dependent
GI364_RS04035	COG1653	transport
GI364_RS04055	COG1797	cobyrinic acid a,c-diamide synthase activity
GI364_RS04060	COG1492	cobalamin metabolic process
GI364_RS04070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_RS04075	COG0406	alpha-ribazole phosphatase activity
GI364_RS04085	COG2096	Adenosyltransferase
GI364_RS04095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_RS04100	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GI364_RS04105	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GI364_RS04110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GI364_RS04120	COG0406	alpha-ribazole phosphatase activity
GI364_RS04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_RS04135	COG0697	spore germination
GI364_RS04175	COG2894	cell division
GI364_RS04225	COG5001	Diguanylate cyclase
GI364_RS04225	COG3300	MHYT domain
GI364_RS04260	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GI364_RS04290	COG2200	EAL domain
GI364_RS04325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GI364_RS04330	COG0372	Belongs to the citrate synthase family
GI364_RS04335	COG1921	L-seryl-tRNASec selenium transferase activity
GI364_RS04340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GI364_RS04355	COG2814	Major facilitator Superfamily
GI364_RS04380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GI364_RS04390	COG2718	Belongs to the UPF0229 family
GI364_RS04395	COG2719	SpoVR family
GI364_RS04400	COG1595	DNA-templated transcription, initiation
GI364_RS04445	COG1595	DNA-templated transcription, initiation
GI364_RS04460	COG0840	transmembrane signaling receptor activity
GI364_RS04480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_RS04485	COG2329	Antibiotic biosynthesis monooxygenase
GI364_RS04500	COG1309	transcriptional regulator
GI364_RS04510	COG0702	epimerase
GI364_RS04525	COG3835	regulator
GI364_RS04530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GI364_RS04535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI364_RS04540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI364_RS04545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_RS04555	COG0765	amino acid transport
GI364_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI364_RS04570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GI364_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS04600	COG0601	transmembrane transport
GI364_RS04605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS04625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_RS04640	COG0022	dehydrogenase e1 component
GI364_RS04660	COG0179	Fumarylacetoacetate (FAA) hydrolase
GI364_RS04665	COG1802	Transcriptional regulator
GI364_RS04675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_RS04680	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS04695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_RS04705	COG2814	Major facilitator Superfamily
GI364_RS04715	COG2169	Transcriptional regulator
GI364_RS04725	COG0640	Transcriptional regulator
GI364_RS04735	COG0129	dihydroxy-acid dehydratase activity
GI364_RS04740	COG0252	asparaginase activity
GI364_RS04745	COG2226	methyltransferase
GI364_RS04755	COG5002	protein histidine kinase activity
GI364_RS04760	COG0745	RESPONSE REGULATOR receiver
GI364_RS04770	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GI364_RS04780	COG0768	penicillin binding
GI364_RS04785	COG0076	glutamate decarboxylase activity
GI364_RS04805	COG4286	Uncharacterised protein family (UPF0160)
GI364_RS04810	COG2226	methyltransferase
GI364_RS04820	COG2076	Multidrug Resistance protein
GI364_RS04825	COG1175	transmembrane transport
GI364_RS04840	COG1067	ATP-dependent peptidase activity
GI364_RS04850	COG0095	Lipoate-protein ligase
GI364_RS04855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GI364_RS04865	COG2814	Major facilitator Superfamily
GI364_RS04880	COG4585	Histidine kinase
GI364_RS04895	COG0561	phosphatase activity
GI364_RS04925	COG0004	ammonium transporteR
GI364_RS04935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_RS04950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS04955	COG1309	transcriptional regulator
GI364_RS04960	COG1131	(ABC) transporter
GI364_RS04970	COG4895	conserved protein (DUF2196)
GI364_RS04975	COG0488	(ABC) transporter
GI364_RS04980	COG0450	alkyl hydroperoxide reductase
GI364_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS04995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_RS05005	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS05015	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_RS05015	COG1902	pentaerythritol trinitrate reductase activity
GI364_RS05025	COG2814	Major facilitator Superfamily
GI364_RS05030	COG2364	Membrane
GI364_RS05035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI364_RS05070	COG0367	asparagine synthase
GI364_RS05075	COG0626	cystathionine gamma-synthase activity
GI364_RS05080	COG0840	transmembrane signaling receptor activity
GI364_RS05085	COG1725	Transcriptional regulator
GI364_RS05090	COG1131	(ABC) transporter
GI364_RS05105	COG5002	protein histidine kinase activity
GI364_RS05120	COG2197	response regulator
GI364_RS05130	COG2223	nitrite transmembrane transporter activity
GI364_RS05155	COG1304	FMN binding
GI364_RS05160	COG2814	Major facilitator Superfamily
GI364_RS05165	COG3409	Peptidoglycan-binding domain 1 protein
GI364_RS05165	COG3773	Cell wall hydrolase
GI364_RS05170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS05175	COG0492	ferredoxin-NADP+ reductase activity
GI364_RS05180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS05195	COG3336	cytochrome c oxidase
GI364_RS05225	COG4221	oxidoreductase activity
GI364_RS05230	COG0488	(ABC) transporter
GI364_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS05260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_RS05275	COG3385	transposase activity
GI364_RS05280	COG0584	glycerophosphoryl diester phosphodiesterase
GI364_RS05285	COG1970	mechanosensitive ion channel activity
GI364_RS05290	COG0069	glutamate synthase activity
GI364_RS05295	COG0584	glycerophosphoryl diester phosphodiesterase
GI364_RS05305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GI364_RS05305	COG2199	diguanylate cyclase activity
GI364_RS05310	COG0667	Aldo Keto reductase
GI364_RS05315	COG0477	Major facilitator Superfamily
GI364_RS05320	COG2814	Major facilitator Superfamily
GI364_RS05345	COG1175	transmembrane transport
GI364_RS05350	COG0395	ABC-type sugar transport system, permease component
GI364_RS05365	COG0725	ABC transporter, periplasmic molybdate-binding protein
GI364_RS05375	COG3842	ATPase activity
GI364_RS05400	COG0768	penicillin binding
GI364_RS05410	COG2226	methyltransferase
GI364_RS05425	COG5002	protein histidine kinase activity
GI364_RS05430	COG0745	RESPONSE REGULATOR receiver
GI364_RS05440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI364_RS05445	COG0667	Aldo Keto reductase
GI364_RS05455	COG1733	regulation of RNA biosynthetic process
GI364_RS05465	COG0463	Glycosyl transferase, family 2
GI364_RS05470	COG0456	acetyltransferase
GI364_RS05475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI364_RS05480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI364_RS05485	COG1120	ATPase activity
GI364_RS05500	COG2211	Major facilitator Superfamily
GI364_RS05510	COG0393	Putative heavy-metal-binding
GI364_RS05525	COG0697	spore germination
GI364_RS05530	COG0814	amino acid
GI364_RS05560	COG2135	peptidase activity
GI364_RS05570	COG0288	reversible hydration of carbon dioxide
GI364_RS05575	COG2205	protein histidine kinase activity
GI364_RS05580	COG2172	sigma factor antagonist activity
GI364_RS05600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GI364_RS05615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI364_RS05620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GI364_RS05625	COG0154	amidase activity
GI364_RS05630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GI364_RS05635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GI364_RS05640	COG5002	protein histidine kinase activity
GI364_RS05645	COG0019	diaminopimelate decarboxylase activity
GI364_RS05680	COG1164	Oligoendopeptidase f
GI364_RS05690	COG3852	Histidine kinase
GI364_RS05695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GI364_RS05700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GI364_RS05715	COG0126	phosphoglycerate kinase activity
GI364_RS05720	COG0149	triose-phosphate isomerase activity
GI364_RS05730	COG0148	phosphopyruvate hydratase activity
GI364_RS05735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GI364_RS05745	COG0557	exoribonuclease II activity
GI364_RS05775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_RS05840	COG2207	Transcriptional regulator
GI364_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS05860	COG1595	DNA-templated transcription, initiation
GI364_RS05880	COG0346	lactoylglutathione lyase activity
GI364_RS05885	COG2315	Protein conserved in bacteria
GI364_RS05890	COG1802	Transcriptional regulator
GI364_RS05895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GI364_RS05900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_RS05905	COG1335	isochorismatase
GI364_RS05930	COG0514	ATP-dependent DNA helicase (RecQ)
GI364_RS05935	COG0789	Transcriptional regulator
GI364_RS05955	COG2197	response regulator
GI364_RS05960	COG4585	Histidine kinase
GI364_RS05970	COG2814	Major facilitator Superfamily
GI364_RS05975	COG0640	Transcriptional regulator
GI364_RS05980	COG0592	DNA-directed DNA polymerase activity
GI364_RS05985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI364_RS06000	COG3848	Pyruvate phosphate dikinase
GI364_RS06000	COG0574	Belongs to the PEP-utilizing enzyme family
GI364_RS06005	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GI364_RS06010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GI364_RS06040	COG0745	RESPONSE REGULATOR receiver
GI364_RS06045	COG5002	protein histidine kinase activity
GI364_RS06050	COG1175	transmembrane transport
GI364_RS06055	COG0395	ABC-type sugar transport system, permease component
GI364_RS06065	COG3858	chitin binding
GI364_RS06065	COG1388	LysM domain
GI364_RS06075	COG0583	DNA-binding transcription factor activity
GI364_RS06085	COG2259	Doxx family
GI364_RS06090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GI364_RS06135	COG0730	response to heat
GI364_RS06160	COG0281	malic enzyme
GI364_RS06165	COG4989	oxidoreductase activity
GI364_RS06170	COG2318	DinB family
GI364_RS06175	COG2378	regulation of single-species biofilm formation
GI364_RS06190	COG3706	GGDEF domain
GI364_RS06200	COG0326	Molecular chaperone. Has ATPase activity
GI364_RS06210	COG2766	serine protein kinase
GI364_RS06215	COG2718	Belongs to the UPF0229 family
GI364_RS06220	COG2719	SpoVR family
GI364_RS06225	COG4221	oxidoreductase activity
GI364_RS06230	COG2201	protein-glutamate methylesterase activity
GI364_RS06240	COG4191	Histidine kinase
GI364_RS06245	COG3290	protein histidine kinase activity
GI364_RS06245	COG0840	transmembrane signaling receptor activity
GI364_RS06250	COG3300	MHYT domain
GI364_RS06250	COG5001	Diguanylate cyclase
GI364_RS06275	COG2205	protein histidine kinase activity
GI364_RS06280	COG0745	RESPONSE REGULATOR receiver
GI364_RS06290	COG1216	Glycosyl transferase, family 2
GI364_RS06295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS06300	COG0561	phosphatase activity
GI364_RS06305	COG3239	Fatty acid desaturase
GI364_RS06310	COG0386	Belongs to the glutathione peroxidase family
GI364_RS06325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_RS06345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GI364_RS06350	COG1116	anion transmembrane transporter activity
GI364_RS06355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GI364_RS06365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GI364_RS06370	COG0667	Aldo Keto reductase
GI364_RS06380	COG1013	pyruvate-flavodoxin oxidoreductase activity
GI364_RS06385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GI364_RS06385	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_RS06390	COG2814	Major facilitator Superfamily
GI364_RS06395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GI364_RS06405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GI364_RS06420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_RS06445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GI364_RS06590	COG2153	protein acetylation
GI364_RS06625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GI364_RS06630	COG1140	nitrate reductase beta subunit
GI364_RS06640	COG2181	nitrate reductase activity
GI364_RS06680	COG1744	ABC transporter substrate-binding protein PnrA-like
GI364_RS06685	COG3845	ABC transporter
GI364_RS06690	COG4603	Belongs to the binding-protein-dependent transport system permease family
GI364_RS06695	COG1079	Belongs to the binding-protein-dependent transport system permease family
GI364_RS06700	COG4294	response to UV
GI364_RS06705	COG3300	MHYT domain
GI364_RS06705	COG5001	Diguanylate cyclase
GI364_RS06710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GI364_RS06735	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GI364_RS06745	COG3973	AAA domain
GI364_RS06760	COG1053	succinate dehydrogenase
GI364_RS06765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GI364_RS06780	COG1489	DNA binding
GI364_RS06785	COG0006	proline dipeptidase activity
GI364_RS06795	COG0542	response to heat
GI364_RS06805	COG1937	Protein conserved in bacteria
GI364_RS06815	COG2323	membrane
GI364_RS06830	COG0475	glutathione-regulated potassium exporter activity
GI364_RS06830	COG0569	domain protein
GI364_RS06860	COG0154	amidase activity
GI364_RS06885	COG0596	Alpha beta hydrolase
GI364_RS06910	COG1131	(ABC) transporter
GI364_RS06925	COG0601	transmembrane transport
GI364_RS06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS06935	COG0444	Belongs to the ABC transporter superfamily
GI364_RS06940	COG4608	Belongs to the ABC transporter superfamily
GI364_RS06945	COG4166	transmembrane transport
GI364_RS06950	COG2362	D-Aminopeptidase
GI364_RS06955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GI364_RS06960	COG4990	cell redox homeostasis
GI364_RS06985	COG1733	regulation of RNA biosynthetic process
GI364_RS06995	COG1482	cell wall glycoprotein biosynthetic process
GI364_RS07005	COG0133	tryptophan synthase activity
GI364_RS07015	COG2081	HI0933 family
GI364_RS07020	COG1979	alcohol dehydrogenase
GI364_RS07025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GI364_RS07035	COG0109	protoheme IX farnesyltransferase activity
GI364_RS07040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GI364_RS07050	COG1830	Aldolase
GI364_RS07055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GI364_RS07070	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GI364_RS07075	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GI364_RS07085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GI364_RS07090	COG0131	Imidazoleglycerol-phosphate dehydratase
GI364_RS07095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GI364_RS07100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GI364_RS07105	COG0107	imidazoleglycerol-phosphate synthase activity
GI364_RS07110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GI364_RS07110	COG0140	phosphoribosyl-ATP diphosphatase activity
GI364_RS07125	COG1695	Transcriptional regulator
GI364_RS07135	COG2318	DinB family
GI364_RS07145	COG1279	arginine transmembrane transporter activity
GI364_RS07155	COG1122	ATPase activity
GI364_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS07175	COG1309	transcriptional regulator
GI364_RS07180	COG0583	DNA-binding transcription factor activity
GI364_RS07185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GI364_RS07190	COG0482	sulfurtransferase activity
GI364_RS07205	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GI364_RS07210	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_RS07215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GI364_RS07230	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GI364_RS07240	COG1960	acyl-CoA dehydrogenase activity
GI364_RS07245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_RS07250	COG2873	o-acetylhomoserine
GI364_RS07255	COG0460	homoserine dehydrogenase
GI364_RS07270	COG1022	Amp-dependent synthetase and ligase
GI364_RS07290	COG2818	Glycosylase
GI364_RS07295	COG2155	Conserved Protein
GI364_RS07310	COG1940	carbohydrate kinase activity
GI364_RS07325	COG0395	ABC-type sugar transport system, permease component
GI364_RS07335	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GI364_RS07340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GI364_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS07350	COG0800	Aldolase
GI364_RS07355	COG0363	glucosamine-6-phosphate deaminase activity
GI364_RS07365	COG1295	ribonuclease BN
GI364_RS07370	COG1764	response to oxidative stress
GI364_RS07375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GI364_RS07390	COG1363	Peptidase, m42
GI364_RS07395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_RS07400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_RS07420	COG0577	efflux transmembrane transporter activity
GI364_RS07425	COG1136	(ABC) transporter
GI364_RS07445	COG0726	polysaccharide deacetylase
GI364_RS07455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS07460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS07460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS07470	COG0348	domain, Protein
GI364_RS07485	COG1234	tRNA 3'-trailer cleavage
GI364_RS07490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI364_RS07495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_RS07525	COG0167	dihydroorotate dehydrogenase activity
GI364_RS07530	COG1595	DNA-templated transcription, initiation
GI364_RS07545	COG0686	Belongs to the AlaDH PNT family
GI364_RS07550	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_RS07555	COG0396	ATPase activity
GI364_RS07560	COG0719	Fe-S assembly protein
GI364_RS07565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GI364_RS07570	COG0822	iron-sulfur transferase activity
GI364_RS07575	COG0719	Fe-S assembly protein
GI364_RS07585	COG1959	2 iron, 2 sulfur cluster binding
GI364_RS07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_RS07605	COG1309	transcriptional regulator
GI364_RS07610	COG2086	electron transfer activity
GI364_RS07615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GI364_RS07620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GI364_RS07640	COG0626	cystathionine gamma-synthase activity
GI364_RS07645	COG2986	histidine ammonia-lyase
GI364_RS07650	COG0114	fumarate hydratase activity
GI364_RS07655	COG1506	peptidase
GI364_RS07655	COG4946	Tricorn protease homolog
GI364_RS07655	COG0823	Involved in the tonB-independent uptake of proteins
GI364_RS07660	COG0483	inositol monophosphate 1-phosphatase activity
GI364_RS07665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GI364_RS07670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GI364_RS07685	COG0069	glutamate synthase activity
GI364_RS07690	COG0297	glycogen (starch) synthase activity
GI364_RS07695	COG0189	ligase activity
GI364_RS07700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GI364_RS07700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_RS07715	COG0673	inositol 2-dehydrogenase activity
GI364_RS07725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_RS07765	COG1086	Polysaccharide biosynthesis protein
GI364_RS07785	COG1215	transferase activity, transferring glycosyl groups
GI364_RS07800	COG0463	Glycosyl transferase, family 2
GI364_RS07825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_RS07850	COG0587	DNA-directed DNA polymerase activity
GI364_RS07870	COG0537	adenosine 5'-monophosphoramidase activity
GI364_RS07880	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_RS07880	COG1024	Enoyl-CoA hydratase
GI364_RS07885	COG0183	Belongs to the thiolase family
GI364_RS07890	COG1960	acyl-CoA dehydrogenase activity
GI364_RS07895	COG3584	3D domain protein
GI364_RS07900	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GI364_RS07910	COG1703	isobutyryl-CoA mutase activity
GI364_RS07910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS07910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS07915	COG0477	Major facilitator Superfamily
GI364_RS07935	COG0612	Peptidase, M16
GI364_RS07940	COG0612	Peptidase, M16
GI364_RS07945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GI364_RS07955	COG0602	queuosine metabolic process
GI364_RS07960	COG0720	synthase
GI364_RS07965	COG2233	PERMEase
GI364_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS08000	COG1956	GAF domain-containing protein
GI364_RS08010	COG1193	negative regulation of DNA recombination
GI364_RS08020	COG0772	Belongs to the SEDS family
GI364_RS08030	COG0772	Belongs to the SEDS family
GI364_RS08035	COG0456	acetyltransferase
GI364_RS08040	COG0477	Major facilitator Superfamily
GI364_RS08050	COG1982	Orn Lys Arg decarboxylase major
GI364_RS08055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GI364_RS08060	COG0316	Belongs to the HesB IscA family
GI364_RS08065	COG1078	dGTPase activity
GI364_RS08070	COG0586	Pfam SNARE associated Golgi protein
GI364_RS08075	COG1215	transferase activity, transferring glycosyl groups
GI364_RS08080	COG3377	Domain of unknown function (DUF1805)
GI364_RS08085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GI364_RS08095	COG0494	nUDIX hydrolase
GI364_RS08100	COG1013	pyruvate-flavodoxin oxidoreductase activity
GI364_RS08105	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_RS08105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GI364_RS08115	COG3584	3D domain protein
GI364_RS08120	COG0444	Belongs to the ABC transporter superfamily
GI364_RS08125	COG4608	Belongs to the ABC transporter superfamily
GI364_RS08130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS08135	COG0601	transmembrane transport
GI364_RS08140	COG0747	negative chemotaxis
GI364_RS08160	COG4974	Belongs to the 'phage' integrase family
GI364_RS08210	COG2203	Gaf domain
GI364_RS08210	COG2199	diguanylate cyclase activity
GI364_RS08220	COG1309	transcriptional regulator
GI364_RS08255	COG0640	Transcriptional regulator
GI364_RS08260	COG0697	spore germination
GI364_RS08270	COG1733	regulation of RNA biosynthetic process
GI364_RS08275	COG2259	Doxx family
GI364_RS08300	COG0697	spore germination
GI364_RS08305	COG0655	NAD(P)H dehydrogenase (quinone) activity
GI364_RS08310	COG4221	oxidoreductase activity
GI364_RS08320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI364_RS08325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI364_RS08330	COG1272	protein, Hemolysin III
GI364_RS08380	COG3586	endonuclease activity
GI364_RS08425	COG2002	toxin-antitoxin pair type II binding
GI364_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS08505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_RS08520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI364_RS08550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_RS08560	COG2378	regulation of single-species biofilm formation
GI364_RS08595	COG2508	Transcriptional regulator
GI364_RS08600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GI364_RS08645	COG1653	transport
GI364_RS08650	COG1175	transmembrane transport
GI364_RS08655	COG0395	ABC-type sugar transport system, permease component
GI364_RS08660	COG2188	Transcriptional regulator
GI364_RS08670	COG0205	6-phosphofructokinase activity
GI364_RS08680	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GI364_RS08690	COG2721	sulfolactate sulfo-lyase activity
GI364_RS08695	COG2721	sulfolactate sulfo-lyase activity
GI364_RS08700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GI364_RS08705	COG2186	Transcriptional regulator
GI364_RS08730	COG3340	Belongs to the peptidase S51 family
GI364_RS08760	COG1233	COG1233 Phytoene dehydrogenase and related
GI364_RS08815	COG0179	Fumarylacetoacetate (FAA) hydrolase
GI364_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS08830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GI364_RS08835	COG1113	amino acid transport
GI364_RS08855	COG1595	DNA-templated transcription, initiation
GI364_RS08865	COG0477	Major facilitator Superfamily
GI364_RS08870	COG1940	carbohydrate kinase activity
GI364_RS08885	COG0395	ABC-type sugar transport system, permease component
GI364_RS08895	COG0673	inositol 2-dehydrogenase activity
GI364_RS08915	COG1061	Type III restriction enzyme res subunit
GI364_RS08945	COG3250	beta-galactosidase activity
GI364_RS08950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GI364_RS08955	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GI364_RS08985	COG1082	Xylose isomerase domain protein TIM barrel
GI364_RS09015	COG1737	Transcriptional regulator
GI364_RS09020	COG4166	transmembrane transport
GI364_RS09025	COG0601	transmembrane transport
GI364_RS09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS09035	COG0444	Belongs to the ABC transporter superfamily
GI364_RS09040	COG4608	Belongs to the ABC transporter superfamily
GI364_RS09045	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GI364_RS09050	COG0363	glucosamine-6-phosphate deaminase activity
GI364_RS09060	COG0673	inositol 2-dehydrogenase activity
GI364_RS09070	COG0673	inositol 2-dehydrogenase activity
GI364_RS09100	COG0673	inositol 2-dehydrogenase activity
GI364_RS09105	COG1609	Transcriptional regulator
GI364_RS09115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_RS09120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GI364_RS09120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GI364_RS09125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GI364_RS09140	COG1069	ribulokinase activity
GI364_RS09145	COG2271	Major facilitator Superfamily
GI364_RS09160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GI364_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS09175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GI364_RS09180	COG0420	3'-5' exonuclease activity
GI364_RS09185	COG0419	ATPase involved in DNA repair
GI364_RS09190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_RS09200	COG2226	methyltransferase
GI364_RS09210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS09220	COG0653	protein targeting
GI364_RS09225	COG3483	tryptophan 2,3-dioxygenase activity
GI364_RS09235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GI364_RS09265	COG0493	'glutamate synthase
GI364_RS09285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GI364_RS09290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GI364_RS09295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GI364_RS09295	COG3608	succinylglutamate desuccinylase aspartoacylase
GI364_RS09305	COG0561	phosphatase activity
GI364_RS09310	COG2267	carboxylic ester hydrolase activity
GI364_RS09330	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI364_RS09360	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_RS09420	COG0512	Glutamine amidotransferase of anthranilate synthase
GI364_RS09435	COG4974	Belongs to the 'phage' integrase family
GI364_RS09545	COG2084	Dehydrogenase
GI364_RS09550	COG1349	DNA-binding transcription factor activity
GI364_RS09560	COG2376	Dihydroxyacetone kinase
GI364_RS09565	COG1461	Dihydroxyacetone kinase
GI364_RS09570	COG0698	ribose 5-phosphate isomerase
GI364_RS09575	COG1733	regulation of RNA biosynthetic process
GI364_RS09595	COG1612	heme a metabolic process
GI364_RS09620	COG0427	acetyl-CoA hydrolase
GI364_RS09635	COG0196	riboflavin kinase activity
GI364_RS09655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS09660	COG1063	alcohol dehydrogenase
GI364_RS09665	COG2508	Transcriptional regulator
GI364_RS09675	COG0577	efflux transmembrane transporter activity
GI364_RS09675	COG1136	(ABC) transporter
GI364_RS09680	COG1136	(ABC) transporter
GI364_RS09680	COG0577	efflux transmembrane transporter activity
GI364_RS09690	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS09710	COG0583	DNA-binding transcription factor activity
GI364_RS09730	COG1388	LysM domain
GI364_RS09730	COG3858	chitin binding
GI364_RS09735	COG0436	Aminotransferase
GI364_RS09740	COG1522	sequence-specific DNA binding
GI364_RS09750	COG2814	Major facilitator Superfamily
GI364_RS09765	COG1832	CoA-binding protein
GI364_RS09780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GI364_RS09785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GI364_RS09795	COG0070	glutamate synthase
GI364_RS09795	COG0069	glutamate synthase activity
GI364_RS09795	COG0067	glutamate synthase
GI364_RS09800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GI364_RS09805	COG0137	argininosuccinate synthase activity
GI364_RS09810	COG0165	Argininosuccinate lyase
GI364_RS09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GI364_RS09825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GI364_RS09850	COG3906	Belongs to the UPF0473 family
GI364_RS09905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GI364_RS09910	COG1104	cysteine desulfurase activity
GI364_RS09915	COG0301	tRNA thio-modification
GI364_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS09945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_RS09950	COG1024	Enoyl-CoA hydratase
GI364_RS09955	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GI364_RS09960	COG2001	Belongs to the MraZ family
GI364_RS09965	COG0275	rRNA processing
GI364_RS09975	COG0768	penicillin binding
GI364_RS09980	COG0768	penicillin binding
GI364_RS09990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI364_RS09995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GI364_RS10000	COG0772	Belongs to the SEDS family
GI364_RS10010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GI364_RS10015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GI364_RS10020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GI364_RS10035	COG3856	small basic protein
GI364_RS10040	COG0849	cell division
GI364_RS10045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GI364_RS10055	COG1191	sigma factor activity
GI364_RS10060	COG1191	sigma factor activity
GI364_RS10065	COG1873	PFAM PRC-barrel domain
GI364_RS10070	COG1496	oxidoreductase activity
GI364_RS10075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GI364_RS10080	COG0762	integral membrane protein
GI364_RS10085	COG2302	S4 RNA-binding domain
GI364_RS10090	COG3599	regulation of cell shape
GI364_RS10095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GI364_RS10100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GI364_RS10105	COG0564	pseudouridine synthase activity
GI364_RS10110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GI364_RS10115	COG0540	Belongs to the ATCase OTCase family
GI364_RS10120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GI364_RS10125	COG0505	Belongs to the CarA family
GI364_RS10135	COG0284	orotidine-5'-phosphate decarboxylase activity
GI364_RS10150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_RS10165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GI364_RS10170	COG1561	YicC-like family, N-terminal region
GI364_RS10180	COG0194	GDP metabolic process
GI364_RS10185	COG1758	RNA polymerase activity
GI364_RS10190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI364_RS10195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GI364_RS10200	COG0242	peptide deformylase activity
GI364_RS10205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GI364_RS10210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GI364_RS10210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GI364_RS10215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GI364_RS10220	COG0631	protein serine/threonine phosphatase activity
GI364_RS10225	COG0515	serine threonine protein kinase
GI364_RS10225	COG2815	serine threonine protein kinase
GI364_RS10230	COG1162	GTPase activity
GI364_RS10235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GI364_RS10245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GI364_RS10250	COG1302	Protein conserved in bacteria
GI364_RS10255	COG1461	Dihydroxyacetone kinase
GI364_RS10260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GI364_RS10270	COG0688	phosphatidylethanolamine metabolic process
GI364_RS10280	COG0438	transferase activity, transferring glycosyl groups
GI364_RS10295	COG0742	ribosomal rna small subunit methyltransferase
GI364_RS10300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GI364_RS10305	COG1752	Esterase of the alpha-beta hydrolase superfamily
GI364_RS10315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GI364_RS10320	COG1349	DNA-binding transcription factor activity
GI364_RS10325	COG0416	fatty acid biosynthetic process
GI364_RS10330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI364_RS10335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GI364_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS10345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GI364_RS10350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GI364_RS10360	COG1196	nuclear chromosome segregation
GI364_RS10365	COG0552	protein localization to endoplasmic reticulum
GI364_RS10370	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GI364_RS10375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GI364_RS10380	COG0228	four-way junction DNA binding
GI364_RS10400	COG0336	Belongs to the RNA methyltransferase TrmD family
GI364_RS10420	COG3385	transposase activity
GI364_RS10430	COG0564	pseudouridine synthase activity
GI364_RS10450	COG1960	acyl-CoA dehydrogenase activity
GI364_RS10455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GI364_RS10460	COG0656	L-ascorbic acid biosynthetic process
GI364_RS10465	COG0824	Thioesterase
GI364_RS10470	COG0739	heme binding
GI364_RS10485	COG1607	acyl-coa hydrolase
GI364_RS10495	COG0335	large ribosomal subunit rRNA binding
GI364_RS10505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GI364_RS10520	COG0792	nuclease activity
GI364_RS10535	COG0045	succinate-CoA ligase (ADP-forming) activity
GI364_RS10540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GI364_RS10545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GI364_RS10545	COG0758	DNA mediated transformation
GI364_RS10550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GI364_RS10555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GI364_RS10560	COG4974	Belongs to the 'phage' integrase family
GI364_RS10565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GI364_RS10570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GI364_RS10590	COG1677	Flagellar hook-basal body complex protein FliE
GI364_RS10595	COG1766	The M ring may be actively involved in energy transduction
GI364_RS10600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_RS10610	COG1157	protein secretion by the type III secretion system
GI364_RS10640	COG4786	Flagellar basal body rod
GI364_RS10655	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_RS10660	COG1776	CheC inhibitor of MCP methylation
GI364_RS10660	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI364_RS10665	COG2201	protein-glutamate methylesterase activity
GI364_RS10675	COG1338	Plays a role in the flagellum-specific transport system
GI364_RS10680	COG1987	bacterial-type flagellum assembly
GI364_RS10685	COG1684	flagellar biosynthetic protein fliR
GI364_RS10690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI364_RS10695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI364_RS10700	COG1419	protein localization to endoplasmic reticulum
GI364_RS10710	COG0835	chemotaxis
GI364_RS10715	COG1776	CheC inhibitor of MCP methylation
GI364_RS10720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GI364_RS10730	COG0052	Belongs to the universal ribosomal protein uS2 family
GI364_RS10735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GI364_RS10740	COG0528	UMP kinase activity
GI364_RS10745	COG0233	cytoplasmic translational termination
GI364_RS10750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GI364_RS10755	COG4589	Belongs to the CDS family
GI364_RS10760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GI364_RS10765	COG0750	zinc metalloprotease
GI364_RS10770	COG0442	prolyl-tRNA aminoacylation
GI364_RS10775	COG2176	DNA-directed DNA polymerase activity
GI364_RS10780	COG0077	Prephenate dehydratase
GI364_RS10800	COG0697	spore germination
GI364_RS10805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GI364_RS10805	COG0069	glutamate synthase activity
GI364_RS10810	COG1217	gtp-binding protein TYPA
GI364_RS10815	COG0779	Required for maturation of 30S ribosomal subunits
GI364_RS10820	COG0195	Participates in both transcription termination and antitermination
GI364_RS10825	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GI364_RS10835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GI364_RS10840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GI364_RS10850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GI364_RS10855	COG0196	riboflavin kinase activity
GI364_RS10865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GI364_RS10870	COG1185	polyribonucleotide nucleotidyltransferase activity
GI364_RS10875	COG0726	polysaccharide deacetylase
GI364_RS10880	COG0612	Peptidase, M16
GI364_RS10885	COG0756	dUTP diphosphatase activity
GI364_RS10895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI364_RS10905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI364_RS10910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GI364_RS10915	COG0527	aspartate kinase activity
GI364_RS10920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_RS10925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GI364_RS10930	COG0740	serine-type endopeptidase activity
GI364_RS10940	COG1674	ftsk spoiiie
GI364_RS10940	COG4980	gas vesicle protein
GI364_RS10965	COG1426	Protein conserved in bacteria
GI364_RS10970	COG1666	GTP binding
GI364_RS10975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GI364_RS10980	COG1058	Belongs to the CinA family
GI364_RS10980	COG1546	Belongs to the CinA family
GI364_RS10990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GI364_RS10995	COG2137	regulation of response to DNA damage stimulus
GI364_RS11000	COG1418	mRNA catabolic process
GI364_RS11005	COG1692	metallophosphoesterase
GI364_RS11010	COG2359	stage V sporulation protein S
GI364_RS11020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS11040	COG1396	sequence-specific DNA binding
GI364_RS11045	COG1396	sequence-specific DNA binding
GI364_RS11080	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GI364_RS11180	COG3331	DNA recombination
GI364_RS11335	COG3274	enterobacterial common antigen metabolic process
GI364_RS11380	COG0189	ligase activity
GI364_RS11395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS11425	COG0697	spore germination
GI364_RS11440	COG2226	methyltransferase
GI364_RS11445	COG0189	ligase activity
GI364_RS11455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI364_RS11465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GI364_RS11470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GI364_RS11475	COG2521	methyltransferase
GI364_RS11475	COG2136	Putative SAM-dependent methyltransferase
GI364_RS11480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GI364_RS11555	COG0697	spore germination
GI364_RS11565	COG0464	growth
GI364_RS11585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GI364_RS11590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GI364_RS11595	COG0789	Transcriptional regulator
GI364_RS11600	COG0174	glutamine synthetase
GI364_RS11620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GI364_RS11625	COG3942	CHAP domain
GI364_RS11625	COG1388	LysM domain
GI364_RS11630	COG1410	methionine synthase
GI364_RS11630	COG0646	methionine synthase
GI364_RS11635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GI364_RS11635	COG0646	methionine synthase
GI364_RS11645	COG0561	phosphatase activity
GI364_RS11650	COG0423	glycine-tRNA ligase activity
GI364_RS11665	COG2814	Major facilitator Superfamily
GI364_RS11670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_RS11695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_RS11700	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_RS11720	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_RS11735	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_RS11745	COG1113	amino acid transport
GI364_RS11750	COG2720	vancomycin resistance protein
GI364_RS11770	COG0095	Lipoate-protein ligase
GI364_RS11775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GI364_RS11795	COG1376	ErfK ybiS ycfS ynhG family protein
GI364_RS11810	COG1657	PFAM Prenyltransferase squalene oxidase
GI364_RS11820	COG0024	Methionine aminopeptidase
GI364_RS11830	COG0824	Thioesterase
GI364_RS11835	COG0693	protein deglycase activity
GI364_RS11845	COG2409	Drug exporters of the RND superfamily
GI364_RS11845	COG1033	growth of symbiont in host cell
GI364_RS11875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI364_RS11880	COG0697	spore germination
GI364_RS11895	COG0316	Belongs to the HesB IscA family
GI364_RS11900	COG0494	nUDIX hydrolase
GI364_RS11910	COG1686	Belongs to the peptidase S11 family
GI364_RS11915	COG0367	asparagine synthase
GI364_RS11955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GI364_RS11970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GI364_RS11975	COG1072	(Pantothenic acid kinase))
GI364_RS11980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GI364_RS11995	COG0017	Asparaginyl-tRNA synthetase
GI364_RS12000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI364_RS12020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GI364_RS12030	COG0402	S-adenosylhomocysteine deaminase activity
GI364_RS12035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GI364_RS12040	COG1793	dna ligase
GI364_RS12040	COG3285	dna ligase
GI364_RS12055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GI364_RS12055	COG1199	ATP-dependent helicase activity
GI364_RS12065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GI364_RS12065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GI364_RS12070	COG0617	tRNA 3'-terminal CCA addition
GI364_RS12075	COG0438	transferase activity, transferring glycosyl groups
GI364_RS12080	COG1803	Methylglyoxal synthase
GI364_RS12085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GI364_RS12095	COG1694	Mazg nucleotide pyrophosphohydrolase
GI364_RS12100	COG3314	Sporulation integral membrane protein YlbJ
GI364_RS12105	COG1968	undecaprenyl-diphosphatase activity
GI364_RS12110	COG3949	Membrane
GI364_RS12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI364_RS12135	COG5582	Belongs to the UPF0302 family
GI364_RS12155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_RS12160	COG0159	tryptophan synthase activity
GI364_RS12165	COG0133	tryptophan synthase activity
GI364_RS12170	COG0135	phosphoribosylanthranilate isomerase activity
GI364_RS12175	COG0134	indole-3-glycerol-phosphate synthase activity
GI364_RS12180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GI364_RS12185	COG4401	Chorismate mutase type I
GI364_RS12190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GI364_RS12200	COG1335	isochorismatase
GI364_RS12215	COG1363	Peptidase, m42
GI364_RS12220	COG0564	pseudouridine synthase activity
GI364_RS12245	COG0740	serine-type endopeptidase activity
GI364_RS12270	COG1132	(ABC) transporter
GI364_RS12275	COG1132	(ABC) transporter
GI364_RS12280	COG2323	membrane
GI364_RS12285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GI364_RS12295	COG0105	UTP biosynthetic process
GI364_RS12300	COG0142	geranyltranstransferase activity
GI364_RS12320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI364_RS12325	COG0509	glycine decarboxylation via glycine cleavage system
GI364_RS12330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GI364_RS12335	COG1160	GTP binding
GI364_RS12355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GI364_RS12370	COG2959	enzyme of heme biosynthesis
GI364_RS12385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI364_RS12390	COG4862	establishment of competence for transformation
GI364_RS12395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_RS12400	COG1609	Transcriptional regulator
GI364_RS12410	COG0210	DNA helicase
GI364_RS12410	COG0210	DNA helicase
GI364_RS12420	COG2226	methyltransferase
GI364_RS12430	COG1388	LysM domain
GI364_RS12430	COG0791	NLP P60 protein
GI364_RS12440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI364_RS12465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_RS12470	COG3459	Glycosyltransferase 36 associated
GI364_RS12475	COG1063	alcohol dehydrogenase
GI364_RS12490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GI364_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS12500	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS12505	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GI364_RS12510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GI364_RS12550	COG2427	Protein of unknown function (DUF1641)
GI364_RS12555	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS12565	COG0393	Putative heavy-metal-binding
GI364_RS12570	COG0393	Putative heavy-metal-binding
GI364_RS12575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI364_RS12585	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS12590	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GI364_RS12595	COG2151	metal-sulfur cluster biosynthetic enzyme
GI364_RS12610	COG3396	Phenylacetate-CoA oxygenase
GI364_RS12625	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS12630	COG2814	Major facilitator Superfamily
GI364_RS12640	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS12655	COG1842	Phage shock protein A
GI364_RS12660	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GI364_RS12665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GI364_RS12695	COG0708	Exodeoxyribonuclease III
GI364_RS12700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS12720	COG2339	peptidase activity
GI364_RS12735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_RS12750	COG5002	protein histidine kinase activity
GI364_RS12755	COG0745	RESPONSE REGULATOR receiver
GI364_RS12770	COG1187	pseudouridine synthase activity
GI364_RS12775	COG0700	Nucleoside recognition
GI364_RS12780	COG2715	membrane protein required for spore maturation
GI364_RS12785	COG3874	Sporulation protein YtfJ
GI364_RS12795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GI364_RS12800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GI364_RS12805	COG1994	Peptidase M50
GI364_RS12825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI364_RS12835	COG1191	sigma factor activity
GI364_RS12840	COG2172	sigma factor antagonist activity
GI364_RS12855	COG1686	Belongs to the peptidase S11 family
GI364_RS12865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GI364_RS12870	COG4974	Belongs to the 'phage' integrase family
GI364_RS12885	COG1300	Membrane
GI364_RS12890	COG1379	DNA repair
GI364_RS12895	COG0494	nUDIX hydrolase
GI364_RS12900	COG1113	amino acid transport
GI364_RS12905	COG2195	Cleaves the N-terminal amino acid of tripeptides
GI364_RS12910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI364_RS12915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS12915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS12920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS12920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI364_RS12925	COG0321	lipoyl(octanoyl) transferase activity
GI364_RS12930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GI364_RS12935	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_RS12940	COG0022	dehydrogenase e1 component
GI364_RS12945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GI364_RS12950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GI364_RS12960	COG3290	protein histidine kinase activity
GI364_RS12960	COG3829	transcription factor binding
GI364_RS12980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS12995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI364_RS13005	COG1131	(ABC) transporter
GI364_RS13015	COG1138	Cytochrome C-type biogenesis protein
GI364_RS13020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GI364_RS13035	COG2050	protein possibly involved in aromatic compounds catabolism
GI364_RS13040	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_RS13050	COG1902	pentaerythritol trinitrate reductase activity
GI364_RS13055	COG2226	methyltransferase
GI364_RS13060	COG0456	acetyltransferase
GI364_RS13065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_RS13070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI364_RS13075	COG0640	Transcriptional regulator
GI364_RS13085	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_RS13090	COG1131	(ABC) transporter
GI364_RS13110	COG1595	DNA-templated transcription, initiation
GI364_RS13120	COG3300	MHYT domain
GI364_RS13120	COG5001	Diguanylate cyclase
GI364_RS13130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI364_RS13135	COG0456	acetyltransferase
GI364_RS13140	COG0745	RESPONSE REGULATOR receiver
GI364_RS13145	COG0750	zinc metalloprotease
GI364_RS13150	COG0497	DNA recombination
GI364_RS13155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GI364_RS13165	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GI364_RS13170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GI364_RS13185	COG1722	exodeoxyribonuclease VII activity
GI364_RS13190	COG1570	exodeoxyribonuclease VII activity
GI364_RS13195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_RS13200	COG0492	ferredoxin-NADP+ reductase activity
GI364_RS13205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GI364_RS13210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GI364_RS13225	COG1302	Protein conserved in bacteria
GI364_RS13230	COG0439	Biotin carboxylase
GI364_RS13235	COG0511	ligase activity, forming carbon-carbon bonds
GI364_RS13275	COG3854	ATPases associated with a variety of cellular activities
GI364_RS13280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GI364_RS13285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GI364_RS13290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GI364_RS13295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GI364_RS13300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GI364_RS13305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI364_RS13315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GI364_RS13320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GI364_RS13355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_RS13365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GI364_RS13375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GI364_RS13385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GI364_RS13390	COG1994	Peptidase M50
GI364_RS13400	COG2894	cell division
GI364_RS13405	COG0850	regulation of cytokinetic process
GI364_RS13420	COG1077	Cell shape determining protein MreB Mrl
GI364_RS13425	COG2003	Belongs to the UPF0758 family
GI364_RS13440	COG3583	domain protein
GI364_RS13440	COG3584	3D domain protein
GI364_RS13445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GI364_RS13460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GI364_RS13465	COG0285	dihydrofolate synthase activity
GI364_RS13470	COG0525	valine-tRNA ligase activity
GI364_RS13500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GI364_RS13505	COG0113	porphobilinogen synthase activity
GI364_RS13515	COG0181	hydroxymethylbilane synthase activity
GI364_RS13520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI364_RS13525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GI364_RS13530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GI364_RS13540	COG1067	ATP-dependent peptidase activity
GI364_RS13540	COG0470	DNA polymerase III
GI364_RS13545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GI364_RS13550	COG0740	serine-type endopeptidase activity
GI364_RS13555	COG0544	peptidyl-prolyl cis-trans isomerase activity
GI364_RS13580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GI364_RS13585	COG1846	Transcriptional regulator
GI364_RS13590	COG2197	response regulator
GI364_RS13595	COG0484	heat shock protein binding
GI364_RS13605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GI364_RS13610	COG1053	succinate dehydrogenase
GI364_RS13615	COG2009	succinate dehydrogenase
GI364_RS13620	COG0322	excinuclease ABC activity
GI364_RS13645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GI364_RS13655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_RS13660	COG0387	Pfam Sodium calcium exchanger
GI364_RS13695	COG1846	Transcriptional regulator
GI364_RS13700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GI364_RS13715	COG2226	methyltransferase
GI364_RS13740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GI364_RS13750	COG5002	protein histidine kinase activity
GI364_RS13760	COG1794	racemase activity, acting on amino acids and derivatives
GI364_RS13795	COG0583	DNA-binding transcription factor activity
GI364_RS13830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS13835	COG1418	mRNA catabolic process
GI364_RS13860	COG1227	inorganic diphosphatase activity
GI364_RS13870	COG0442	prolyl-tRNA aminoacylation
GI364_RS13890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_RS13895	COG0569	domain protein
GI364_RS13895	COG0475	glutathione-regulated potassium exporter activity
GI364_RS13905	COG2205	protein histidine kinase activity
GI364_RS13910	COG0745	RESPONSE REGULATOR receiver
GI364_RS13960	COG0640	Transcriptional regulator
GI364_RS13970	COG4555	ABC transporter
GI364_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS13995	COG2267	carboxylic ester hydrolase activity
GI364_RS14010	COG0583	DNA-binding transcription factor activity
GI364_RS14025	COG2211	Major facilitator Superfamily
GI364_RS14030	COG0730	response to heat
GI364_RS14035	COG2046	Belongs to the sulfate adenylyltransferase family
GI364_RS14040	COG0175	sulfate reduction
GI364_RS14045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_RS14090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GI364_RS14095	COG0647	UMP catabolic process
GI364_RS14100	COG2096	Adenosyltransferase
GI364_RS14120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GI364_RS14125	COG4187	Peptidase family M20/M25/M40
GI364_RS14135	COG3336	cytochrome c oxidase
GI364_RS14150	COG3773	Cell wall hydrolase
GI364_RS14150	COG3409	Peptidoglycan-binding domain 1 protein
GI364_RS14155	COG0463	Glycosyl transferase, family 2
GI364_RS14170	COG1566	PFAM secretion protein HlyD family protein
GI364_RS14175	COG2814	Major facilitator Superfamily
GI364_RS14180	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GI364_RS14190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GI364_RS14195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GI364_RS14205	COG1388	LysM domain
GI364_RS14205	COG0791	NLP P60 protein
GI364_RS14210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI364_RS14215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI364_RS14240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GI364_RS14245	COG2814	Major facilitator Superfamily
GI364_RS14260	COG0714	Associated with various cellular activities
GI364_RS14265	COG3263	regulation of cellular component size
GI364_RS14280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_RS14285	COG0596	Alpha beta hydrolase
GI364_RS14290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GI364_RS14295	COG1169	isochorismate synthase
GI364_RS14305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GI364_RS14310	COG1575	Belongs to the MenA family. Type 1 subfamily
GI364_RS14320	COG0384	phenazine biosynthesis protein PhzF
GI364_RS14335	COG0531	amino acid
GI364_RS14345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GI364_RS14355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_RS14360	COG1937	Protein conserved in bacteria
GI364_RS14365	COG2217	Heavy metal translocating P-type atpase
GI364_RS14405	COG1686	Belongs to the peptidase S11 family
GI364_RS14425	COG1435	thymidine kinase activity
GI364_RS14430	COG0640	Transcriptional regulator
GI364_RS14450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GI364_RS14465	COG2808	Putative FMN-binding domain
GI364_RS14470	COG0531	amino acid
GI364_RS14525	COG0390	transport system, permease component
GI364_RS14530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI364_RS14535	COG1131	(ABC) transporter
GI364_RS14540	COG1511	domain protein
GI364_RS14540	COG0842	Transport permease protein
GI364_RS14545	COG1309	transcriptional regulator
GI364_RS14580	COG2009	succinate dehydrogenase
GI364_RS14585	COG2814	Major facilitator Superfamily
GI364_RS14590	COG1959	2 iron, 2 sulfur cluster binding
GI364_RS14600	COG0730	response to heat
GI364_RS14605	COG0243	molybdopterin cofactor binding
GI364_RS14610	COG0437	4 iron, 4 sulfur cluster binding
GI364_RS14615	COG0583	DNA-binding transcription factor activity
GI364_RS14635	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_RS14640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS14640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS14645	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS14660	COG1510	regulation of RNA biosynthetic process
GI364_RS14670	COG0492	ferredoxin-NADP+ reductase activity
GI364_RS14680	COG0789	Transcriptional regulator
GI364_RS14685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_RS14695	COG2814	Major facilitator Superfamily
GI364_RS14745	COG0697	spore germination
GI364_RS14750	COG5002	protein histidine kinase activity
GI364_RS14760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_RS14775	COG0531	amino acid
GI364_RS14780	COG0583	DNA-binding transcription factor activity
GI364_RS14810	COG0477	Major facilitator Superfamily
GI364_RS14815	COG0180	Tryptophanyl-tRNA synthetase
GI364_RS14850	COG2814	Major facilitator Superfamily
GI364_RS14865	COG4974	Belongs to the 'phage' integrase family
GI364_RS14905	COG2002	toxin-antitoxin pair type II binding
GI364_RS14910	COG3328	transposase activity
GI364_RS14995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS15000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GI364_RS15005	COG1683	Conserved Protein
GI364_RS15040	COG4974	Belongs to the 'phage' integrase family
GI364_RS15055	COG4974	Belongs to the 'phage' integrase family
GI364_RS15060	COG4974	Belongs to the 'phage' integrase family
GI364_RS15085	COG2002	toxin-antitoxin pair type II binding
GI364_RS15155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GI364_RS15170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GI364_RS15175	COG0305	Participates in initiation and elongation during chromosome replication
GI364_RS15175	COG0358	DNA primase activity
GI364_RS15180	COG0574	Belongs to the PEP-utilizing enzyme family
GI364_RS15180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GI364_RS15185	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GI364_RS15190	COG0517	IMP dehydrogenase activity
GI364_RS15195	COG1381	Involved in DNA repair and RecF pathway recombination
GI364_RS15205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GI364_RS15210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GI364_RS15215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GI364_RS15220	COG1480	7TM receptor with intracellular HD hydrolase
GI364_RS15225	COG1702	phosphate starvation-inducible protein PhoH
GI364_RS15245	COG1610	YqeY-like protein
GI364_RS15250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GI364_RS15255	COG1283	sodium-dependent phosphate transmembrane transporter activity
GI364_RS15260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GI364_RS15265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI364_RS15270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GI364_RS15275	COG2264	protein methyltransferase activity
GI364_RS15290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GI364_RS15295	COG1420	regulation of RNA biosynthetic process
GI364_RS15300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GI364_RS15305	COG0481	GTPase activity
GI364_RS15315	COG0741	lytic transglycosylase activity
GI364_RS15325	COG0268	Binds directly to 16S ribosomal RNA
GI364_RS15330	COG1466	dna polymerase III delta subunit
GI364_RS15335	COG1252	NADH dehydrogenase
GI364_RS15355	COG1321	iron dependent repressor
GI364_RS15365	COG0799	negative regulation of ribosome biogenesis
GI364_RS15370	COG1713	HD superfamily hydrolase involved in NAD metabolism
GI364_RS15375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GI364_RS15380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GI364_RS15385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GI364_RS15390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GI364_RS15400	COG0768	penicillin binding
GI364_RS15410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GI364_RS15415	COG4472	Bacterial protein of unknown function (DUF965)
GI364_RS15420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GI364_RS15430	COG0628	permease
GI364_RS15435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_RS15440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_RS15450	COG1104	cysteine desulfurase activity
GI364_RS15455	COG1959	2 iron, 2 sulfur cluster binding
GI364_RS15475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GI364_RS15480	COG0124	histidyl-tRNA synthetase
GI364_RS15490	COG1921	L-seryl-tRNASec selenium transferase activity
GI364_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS15525	COG1131	(ABC) transporter
GI364_RS15540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GI364_RS15545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GI364_RS15545	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GI364_RS15550	COG0183	Belongs to the thiolase family
GI364_RS15575	COG2226	methyltransferase
GI364_RS15585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI364_RS15595	COG0667	Aldo Keto reductase
GI364_RS15600	COG0303	'Molybdopterin
GI364_RS15605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_RS15610	COG1131	(ABC) transporter
GI364_RS15620	COG1131	(ABC) transporter
GI364_RS15625	COG1725	Transcriptional regulator
GI364_RS15635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GI364_RS15670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GI364_RS15685	COG2211	Major facilitator Superfamily
GI364_RS15705	COG0531	amino acid
GI364_RS15710	COG1309	transcriptional regulator
GI364_RS15715	COG0477	Major facilitator Superfamily
GI364_RS15720	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GI364_RS15725	COG1074	ATP-dependent DNA helicase activity
GI364_RS15730	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GI364_RS15735	COG4717	serine-type aminopeptidase activity
GI364_RS15740	COG0420	3'-5' exonuclease activity
GI364_RS15745	COG2130	NADP-dependent
GI364_RS15750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GI364_RS15770	COG1321	iron dependent repressor
GI364_RS15785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GI364_RS15790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GI364_RS15795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GI364_RS15810	COG4129	membrane
GI364_RS15825	COG0667	Aldo Keto reductase
GI364_RS15855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_RS15860	COG0569	domain protein
GI364_RS15870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS15875	COG1490	D-aminoacyl-tRNA deacylase activity
GI364_RS15880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI364_RS15885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI364_RS15890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GI364_RS15890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GI364_RS15895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GI364_RS15900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_RS15905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_RS15915	COG2244	polysaccharide biosynthetic process
GI364_RS15920	COG2323	membrane
GI364_RS15940	COG0343	queuine tRNA-ribosyltransferase activity
GI364_RS15945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GI364_RS15950	COG3693	PFAM glycoside hydrolase, family 10
GI364_RS15955	COG1191	sigma factor activity
GI364_RS15960	COG2255	four-way junction helicase activity
GI364_RS15965	COG0632	four-way junction helicase activity
GI364_RS15980	COG0217	transcriptional regulatory protein
GI364_RS16010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GI364_RS16015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_RS16020	COG1193	negative regulation of DNA recombination
GI364_RS16035	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GI364_RS16040	COG0072	phenylalanine-tRNA ligase activity
GI364_RS16040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GI364_RS16045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GI364_RS16050	COG0667	Aldo Keto reductase
GI364_RS16055	COG0697	spore germination
GI364_RS16060	COG2211	Major facilitator Superfamily
GI364_RS16065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_RS16070	COG2723	6-phospho-beta-galactosidase activity
GI364_RS16075	COG1486	melibiose metabolic process
GI364_RS16095	COG0644	oxidoreductase
GI364_RS16100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GI364_RS16130	COG1612	heme a metabolic process
GI364_RS16135	COG0109	protoheme IX farnesyltransferase activity
GI364_RS16155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GI364_RS16190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GI364_RS16210	COG3253	May function as heme-dependent peroxidase
GI364_RS16215	COG0277	FAD linked oxidase domain protein
GI364_RS16220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_RS16225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI364_RS16235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS16260	COG1172	Belongs to the binding-protein-dependent transport system permease family
GI364_RS16265	COG0559	Belongs to the binding-protein-dependent transport system permease family
GI364_RS16285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GI364_RS16290	COG2814	Major facilitator Superfamily
GI364_RS16295	COG0789	Transcriptional regulator
GI364_RS16305	COG2183	response to ionizing radiation
GI364_RS16325	COG3511	phospholipase C
GI364_RS16330	COG0531	amino acid
GI364_RS16335	COG1760	l-serine dehydratase
GI364_RS16340	COG1760	l-serine dehydratase
GI364_RS16355	COG2966	Psort location CytoplasmicMembrane, score
GI364_RS16360	COG3610	response to peptide
GI364_RS16365	COG2124	cytochrome p450
GI364_RS16375	COG1136	(ABC) transporter
GI364_RS16375	COG0577	efflux transmembrane transporter activity
GI364_RS16380	COG0003	Pfam Anion-transporting ATPase
GI364_RS16410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI364_RS16415	COG1459	type II secretion system
GI364_RS16455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GI364_RS16465	COG0673	inositol 2-dehydrogenase activity
GI364_RS16475	COG1024	Enoyl-CoA hydratase
GI364_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS16495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GI364_RS16520	COG1960	acyl-CoA dehydrogenase activity
GI364_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS16550	COG2030	dehydratase
GI364_RS16555	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS16565	COG1294	oxidase, subunit
GI364_RS16570	COG1271	oxidase subunit
GI364_RS16580	COG1414	Transcriptional regulator
GI364_RS16585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI364_RS16590	COG0385	Bile acid
GI364_RS16600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_RS16605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI364_RS16610	COG2267	carboxylic ester hydrolase activity
GI364_RS16615	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GI364_RS16620	COG0402	S-adenosylhomocysteine deaminase activity
GI364_RS16635	COG2186	Transcriptional regulator
GI364_RS16665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GI364_RS16670	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GI364_RS16680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GI364_RS16685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GI364_RS16695	COG2376	Dihydroxyacetone kinase
GI364_RS16700	COG1461	Dihydroxyacetone kinase
GI364_RS16715	COG0668	transmembrane transport
GI364_RS16725	COG2972	Histidine kinase
GI364_RS16725	COG0745	RESPONSE REGULATOR receiver
GI364_RS16735	COG3239	Fatty acid desaturase
GI364_RS16775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GI364_RS16780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_RS16810	COG3546	catalase activity
GI364_RS16815	COG4846	Membrane protein involved in cytochrome C biogenesis
GI364_RS16840	COG0586	Pfam SNARE associated Golgi protein
GI364_RS16845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI364_RS16850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GI364_RS16855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GI364_RS16865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GI364_RS16885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GI364_RS16895	COG2272	Belongs to the type-B carboxylesterase lipase family
GI364_RS16905	COG0601	transmembrane transport
GI364_RS16910	COG1309	transcriptional regulator
GI364_RS16915	COG2814	Major facilitator Superfamily
GI364_RS16995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GI364_RS17000	COG0705	Rhomboid family
GI364_RS17000	COG0457	Tetratricopeptide repeat
GI364_RS17010	COG0501	Belongs to the peptidase M48B family
GI364_RS17030	COG0517	IMP dehydrogenase activity
GI364_RS17040	COG2197	response regulator
GI364_RS17045	COG4585	Histidine kinase
GI364_RS17055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GI364_RS17065	COG1809	phosphosulfolactate synthase activity
GI364_RS17070	COG1971	Probably functions as a manganese efflux pump
GI364_RS17075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GI364_RS17090	COG0083	homoserine kinase activity
GI364_RS17095	COG0460	homoserine dehydrogenase
GI364_RS17105	COG0066	3-isopropylmalate dehydratase activity
GI364_RS17110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GI364_RS17115	COG0473	3-isopropylmalate dehydrogenase activity
GI364_RS17120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GI364_RS17125	COG0440	acetolactate synthase activity
GI364_RS17130	COG0028	Belongs to the TPP enzyme family
GI364_RS17135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GI364_RS17160	COG2224	Isocitrate lyase
GI364_RS17165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GI364_RS17175	COG1119	ATPase activity
GI364_RS17180	COG5002	protein histidine kinase activity
GI364_RS17190	COG0604	alcohol dehydrogenase
GI364_RS17200	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS17205	COG3383	formate dehydrogenase (NAD+) activity
GI364_RS17255	COG1271	oxidase subunit
GI364_RS17260	COG1294	oxidase, subunit
GI364_RS17275	COG0730	response to heat
GI364_RS17295	COG3511	phospholipase C
GI364_RS17310	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS17330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GI364_RS17335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GI364_RS17350	COG1584	GPR1 FUN34 yaaH family protein
GI364_RS17385	COG3971	2-oxopent-4-enoate hydratase activity
GI364_RS17405	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS17410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GI364_RS17415	COG4638	Rieske (2fe-2S)
GI364_RS17420	COG2271	Major facilitator Superfamily
GI364_RS17425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GI364_RS17435	COG3852	Histidine kinase
GI364_RS17440	COG1621	beta-fructofuranosidase activity
GI364_RS17450	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GI364_RS17460	COG1940	carbohydrate kinase activity
GI364_RS17465	COG0395	ABC-type sugar transport system, permease component
GI364_RS17470	COG1175	transmembrane transport
GI364_RS17490	COG4191	Histidine kinase
GI364_RS17515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GI364_RS17530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GI364_RS17535	COG3858	chitin binding
GI364_RS17535	COG1388	LysM domain
GI364_RS17570	COG0640	Transcriptional regulator
GI364_RS17625	COG3858	chitin binding
GI364_RS17625	COG1388	LysM domain
GI364_RS17635	COG0640	Transcriptional regulator
GI364_RS17640	COG1971	Probably functions as a manganese efflux pump
GI364_RS17665	COG0714	Associated with various cellular activities
GI364_RS17690	COG1132	(ABC) transporter
GI364_RS17695	COG1132	(ABC) transporter
GI364_RS17705	COG1827	regulation of RNA biosynthetic process
GI364_RS17715	COG1757	Na H antiporter
GI364_RS17720	COG2155	Conserved Protein
GI364_RS17725	COG1011	Hydrolase
GI364_RS17730	COG2233	PERMEase
GI364_RS17740	COG2814	Major facilitator Superfamily
GI364_RS17750	COG0095	Lipoate-protein ligase
GI364_RS17755	COG0583	DNA-binding transcription factor activity
GI364_RS17765	COG0697	spore germination
GI364_RS17770	COG3264	Mechanosensitive ion channel
GI364_RS17770	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GI364_RS17790	COG2814	Major facilitator Superfamily
GI364_RS17800	COG2197	response regulator
GI364_RS17805	COG4585	Histidine kinase
GI364_RS17825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI364_RS17830	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GI364_RS17835	COG0835	chemotaxis
GI364_RS17840	COG0840	transmembrane signaling receptor activity
GI364_RS17845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI364_RS17870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI364_RS17895	COG1845	cytochrome c oxidase, subunit III
GI364_RS17900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GI364_RS17905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI364_RS17910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS17915	COG2309	aminopeptidase activity
GI364_RS17925	COG2313	pseudouridylate synthase activity
GI364_RS17945	COG2205	protein histidine kinase activity
GI364_RS17950	COG0745	RESPONSE REGULATOR receiver
GI364_RS17955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS17960	COG1136	(ABC) transporter
GI364_RS17960	COG0577	efflux transmembrane transporter activity
GI364_RS17965	COG1136	(ABC) transporter
GI364_RS17975	COG5434	Belongs to the glycosyl hydrolase 28 family
GI364_RS17975	COG4632	Exopolysaccharide biosynthesis protein
GI364_RS17985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GI364_RS17995	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS18005	COG2353	YceI-like domain
GI364_RS18010	COG1741	Belongs to the pirin family
GI364_RS18020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS18085	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_RS18110	COG1335	isochorismatase
GI364_RS18165	COG1162	GTPase activity
GI364_RS18185	COG2814	Major facilitator Superfamily
GI364_RS18190	COG1309	transcriptional regulator
GI364_RS18200	COG0572	uridine kinase
GI364_RS18215	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS18220	COG1132	(ABC) transporter
GI364_RS18225	COG1132	(ABC) transporter
GI364_RS18240	COG1691	(AIR) carboxylase
GI364_RS18245	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GI364_RS18250	COG1606	tRNA processing
GI364_RS18260	COG0667	Aldo Keto reductase
GI364_RS18265	COG0667	Aldo Keto reductase
GI364_RS18270	COG1733	regulation of RNA biosynthetic process
GI364_RS18280	COG1139	Iron-sulfur cluster binding protein
GI364_RS18290	COG2186	Transcriptional regulator
GI364_RS18295	COG0277	FAD linked oxidase domain protein
GI364_RS18300	COG0247	lactate metabolic process
GI364_RS18305	COG0277	FAD linked oxidase domain protein
GI364_RS18310	COG1131	(ABC) transporter
GI364_RS18365	COG0747	negative chemotaxis
GI364_RS18370	COG2207	Transcriptional regulator
GI364_RS18375	COG4608	Belongs to the ABC transporter superfamily
GI364_RS18385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS18390	COG0601	transmembrane transport
GI364_RS18400	COG1070	Carbohydrate kinase
GI364_RS18415	COG1063	alcohol dehydrogenase
GI364_RS18420	COG1175	transmembrane transport
GI364_RS18425	COG1175	transmembrane transport
GI364_RS18430	COG1653	transport
GI364_RS18435	COG1349	DNA-binding transcription factor activity
GI364_RS18440	COG1070	Carbohydrate kinase
GI364_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS18465	COG0673	inositol 2-dehydrogenase activity
GI364_RS18470	COG0395	ABC-type sugar transport system, permease component
GI364_RS18475	COG1175	transmembrane transport
GI364_RS18480	COG2182	Extracellular solute-binding protein
GI364_RS18485	COG1312	Catalyzes the dehydration of D-mannonate
GI364_RS18490	COG1802	Transcriptional regulator
GI364_RS18500	COG0840	transmembrane signaling receptor activity
GI364_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS18525	COG1349	DNA-binding transcription factor activity
GI364_RS18530	COG1070	Carbohydrate kinase
GI364_RS18535	COG1904	glucuronate isomerase
GI364_RS18540	COG0800	Aldolase
GI364_RS18545	COG2721	sulfolactate sulfo-lyase activity
GI364_RS18550	COG1609	Transcriptional regulator
GI364_RS18555	COG0246	Mannitol dehydrogenase
GI364_RS18560	COG1349	DNA-binding transcription factor activity
GI364_RS18575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_RS18580	COG1940	carbohydrate kinase activity
GI364_RS18585	COG0395	ABC-type sugar transport system, permease component
GI364_RS18590	COG1175	transmembrane transport
GI364_RS18600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GI364_RS18605	COG1085	galactose-1-phosphate uridylyltransferase
GI364_RS18610	COG1349	DNA-binding transcription factor activity
GI364_RS18620	COG2723	6-phospho-beta-galactosidase activity
GI364_RS18630	COG1940	carbohydrate kinase activity
GI364_RS18645	COG2084	Dehydrogenase
GI364_RS18655	COG0395	ABC-type sugar transport system, permease component
GI364_RS18660	COG1175	transmembrane transport
GI364_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS18675	COG3250	beta-galactosidase activity
GI364_RS18730	COG0395	ABC-type sugar transport system, permease component
GI364_RS18735	COG1175	transmembrane transport
GI364_RS18760	COG1850	ribulose-bisphosphate carboxylase activity
GI364_RS18775	COG3408	Glycogen debranching enzyme
GI364_RS18780	COG3408	Glycogen debranching enzyme
GI364_RS18790	COG1349	DNA-binding transcription factor activity
GI364_RS18795	COG4952	isomerase
GI364_RS18800	COG3347	Dehydrogenase
GI364_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS18805	COG1070	Carbohydrate kinase
GI364_RS18810	COG0667	Aldo Keto reductase
GI364_RS18815	COG2084	Dehydrogenase
GI364_RS18820	COG0352	thiamine-phosphate diphosphorylase activity
GI364_RS18825	COG4948	Mandelate Racemase Muconate Lactonizing
GI364_RS18830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GI364_RS18835	COG2271	Major facilitator Superfamily
GI364_RS18845	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_RS18855	COG2376	Dihydroxyacetone kinase
GI364_RS18860	COG1461	Dihydroxyacetone kinase
GI364_RS18865	COG0149	triose-phosphate isomerase activity
GI364_RS18870	COG1349	DNA-binding transcription factor activity
GI364_RS18885	COG4221	oxidoreductase activity
GI364_RS18890	COG0371	Dehydrogenase
GI364_RS18900	COG0395	ABC-type sugar transport system, permease component
GI364_RS18920	COG0395	ABC-type sugar transport system, permease component
GI364_RS18925	COG1175	transmembrane transport
GI364_RS18940	COG1609	Transcriptional regulator
GI364_RS18960	COG0395	ABC-type sugar transport system, permease component
GI364_RS18965	COG1175	transmembrane transport
GI364_RS18970	COG1609	Transcriptional regulator
GI364_RS18975	COG3344	reverse transcriptase
GI364_RS18990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS19030	COG0741	lytic transglycosylase activity
GI364_RS19035	COG0237	dephospho-CoA kinase activity
GI364_RS19040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GI364_RS19045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_RS19045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI364_RS19050	COG0039	L-malate dehydrogenase activity
GI364_RS19055	COG0538	isocitrate dehydrogenase activity
GI364_RS19060	COG2205	protein histidine kinase activity
GI364_RS19065	COG0745	RESPONSE REGULATOR receiver
GI364_RS19070	COG0180	Tryptophanyl-tRNA synthetase
GI364_RS19080	COG0205	6-phosphofructokinase activity
GI364_RS19085	COG0825	malonyl-CoA metabolic process
GI364_RS19090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GI364_RS19100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GI364_RS19105	COG0587	DNA-directed DNA polymerase activity
GI364_RS19110	COG4109	DRTGG domain
GI364_RS19130	COG0352	thiamine-phosphate diphosphorylase activity
GI364_RS19135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GI364_RS19140	COG0351	phosphomethylpyrimidine kinase
GI364_RS19145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GI364_RS19150	COG1396	sequence-specific DNA binding
GI364_RS19165	COG1438	arginine binding
GI364_RS19175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GI364_RS19190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GI364_RS19195	COG3679	Belongs to the UPF0342 family
GI364_RS19200	COG2346	COG2346, Truncated hemoglobins
GI364_RS19210	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GI364_RS19215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GI364_RS19225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GI364_RS19230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_RS19230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_RS19240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI364_RS19240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI364_RS19245	COG1045	serine acetyltransferase
GI364_RS19250	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_RS19255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI364_RS19270	COG0569	domain protein
GI364_RS19270	COG0475	glutathione-regulated potassium exporter activity
GI364_RS19275	COG4496	protein, YerC YecD
GI364_RS19295	COG0785	Cytochrome C biogenesis protein
GI364_RS19300	COG5002	protein histidine kinase activity
GI364_RS19325	COG0735	belongs to the Fur family
GI364_RS19335	COG1121	(ABC) transporter
GI364_RS19345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GI364_RS19355	COG1234	tRNA 3'-trailer cleavage
GI364_RS19370	COG4152	abc transporter atp-binding protein
GI364_RS19405	COG2814	Major facilitator Superfamily
GI364_RS19415	COG0535	radical SAM domain protein
GI364_RS19420	COG1533	DNA photolyase activity
GI364_RS19425	COG2814	Major facilitator Superfamily
GI364_RS19430	COG2226	methyltransferase
GI364_RS19525	COG1396	sequence-specific DNA binding
GI364_RS19565	COG0582	viral genome integration into host DNA
GI364_RS19580	COG1611	Belongs to the LOG family
GI364_RS19585	COG1506	peptidase
GI364_RS19590	COG0546	phosphoglycolate phosphatase activity
GI364_RS19620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS19630	COG0653	protein targeting
GI364_RS19650	COG0463	Glycosyl transferase, family 2
GI364_RS19650	COG0457	Tetratricopeptide repeat
GI364_RS19675	COG1256	bacterial-type flagellum assembly
GI364_RS19675	COG4786	Flagellar basal body rod
GI364_RS19705	COG1607	acyl-coa hydrolase
GI364_RS19710	COG1040	competence protein
GI364_RS19715	COG1307	EDD domain protein, DegV family
GI364_RS19720	COG5002	protein histidine kinase activity
GI364_RS19725	COG0745	RESPONSE REGULATOR receiver
GI364_RS19730	COG3800	Transcriptional regulator
GI364_RS19730	COG1396	sequence-specific DNA binding
GI364_RS19740	COG2197	response regulator
GI364_RS19750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GI364_RS19770	COG1278	Cold shock
GI364_RS19775	COG2814	Major facilitator Superfamily
GI364_RS19785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_RS19790	COG0521	Mo-molybdopterin cofactor biosynthetic process
GI364_RS19790	COG0315	cyclic pyranopterin monophosphate synthase activity
GI364_RS19805	COG1122	ATPase activity
GI364_RS19810	COG1122	ATPase activity
GI364_RS19815	COG0697	spore germination
GI364_RS19820	COG3321	synthase
GI364_RS19820	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS19820	COG0604	alcohol dehydrogenase
GI364_RS19825	COG1609	Transcriptional regulator
GI364_RS19830	COG1070	Carbohydrate kinase
GI364_RS19835	COG2271	Major facilitator Superfamily
GI364_RS19840	COG3547	Transposase (IS116 IS110 IS902 family)
GI364_RS19845	COG2363	Small membrane protein
GI364_RS19850	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GI364_RS19860	COG1914	H( )-stimulated, divalent metal cation uptake system
GI364_RS19870	COG0561	phosphatase activity
GI364_RS19910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GI364_RS19915	COG1181	Belongs to the D-alanine--D-alanine ligase family
GI364_RS19920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GI364_RS19940	COG0704	Plays a role in the regulation of phosphate uptake
GI364_RS19945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI364_RS19950	COG2814	Major facilitator Superfamily
GI364_RS19960	COG1595	DNA-templated transcription, initiation
GI364_RS19965	COG3153	acetyltransferase
GI364_RS19965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI364_RS19970	COG1597	lipid kinase activity
GI364_RS20000	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS20005	COG0187	DNA topoisomerase II activity
GI364_RS20010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI364_RS20020	COG0579	oxidoreductase
GI364_RS20025	COG0534	Mate efflux family protein
GI364_RS20030	COG0583	DNA-binding transcription factor activity
GI364_RS20035	COG0028	Belongs to the TPP enzyme family
GI364_RS20040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI364_RS20060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_RS20065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI364_RS20090	COG0395	ABC-type sugar transport system, permease component
GI364_RS20105	COG3328	transposase activity
GI364_RS20110	COG1011	Hydrolase
GI364_RS20120	COG0747	negative chemotaxis
GI364_RS20130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS20135	COG0444	Belongs to the ABC transporter superfamily
GI364_RS20140	COG4608	Belongs to the ABC transporter superfamily
GI364_RS20165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GI364_RS20170	COG1122	ATPase activity
GI364_RS20200	COG1609	Transcriptional regulator
GI364_RS20220	COG2160	L-arabinose isomerase activity
GI364_RS20230	COG1252	NADH dehydrogenase
GI364_RS20245	COG0659	secondary active sulfate transmembrane transporter activity
GI364_RS20250	COG1472	Belongs to the glycosyl hydrolase 3 family
GI364_RS20275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI364_RS20285	COG1278	Cold shock
GI364_RS20295	COG3239	Fatty acid desaturase
GI364_RS20300	COG0667	Aldo Keto reductase
GI364_RS20305	COG0656	L-ascorbic acid biosynthetic process
GI364_RS20310	COG2207	Transcriptional regulator
GI364_RS20315	COG4608	Belongs to the ABC transporter superfamily
GI364_RS20320	COG0444	Belongs to the ABC transporter superfamily
GI364_RS20325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GI364_RS20330	COG0601	transmembrane transport
GI364_RS20335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS20340	COG0823	Involved in the tonB-independent uptake of proteins
GI364_RS20340	COG1506	peptidase
GI364_RS20340	COG4946	Tricorn protease homolog
GI364_RS20345	COG0747	negative chemotaxis
GI364_RS20390	COG0189	ligase activity
GI364_RS20400	COG0488	(ABC) transporter
GI364_RS20410	COG1331	Highly conserved protein containing a thioredoxin domain
GI364_RS20415	COG0583	DNA-binding transcription factor activity
GI364_RS20450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GI364_RS20455	COG0673	inositol 2-dehydrogenase activity
GI364_RS20460	COG1083	cytidylyl-transferase
GI364_RS20465	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS20475	COG2089	acid synthase
GI364_RS20480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GI364_RS20485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GI364_RS20495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GI364_RS20500	COG0116	Belongs to the methyltransferase superfamily
GI364_RS20510	COG0492	ferredoxin-NADP+ reductase activity
GI364_RS20515	COG4106	trans-aconitate 2-methyltransferase activity
GI364_RS20520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GI364_RS20525	COG0604	alcohol dehydrogenase
GI364_RS20535	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GI364_RS20550	COG1278	Cold shock
GI364_RS20560	COG1131	(ABC) transporter
GI364_RS20565	COG1597	lipid kinase activity
GI364_RS20570	COG4990	cell redox homeostasis
GI364_RS20575	COG2197	response regulator
GI364_RS20580	COG4585	Histidine kinase
GI364_RS20585	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI364_RS20590	COG1271	oxidase subunit
GI364_RS20595	COG1294	oxidase, subunit
GI364_RS20600	COG1022	Amp-dependent synthetase and ligase
GI364_RS20625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GI364_RS20625	COG0723	plastoquinol--plastocyanin reductase activity
GI364_RS20630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GI364_RS20645	COG1725	Transcriptional regulator
GI364_RS20670	COG3384	dioxygenase
GI364_RS20675	COG0531	amino acid
GI364_RS20700	COG2226	methyltransferase
GI364_RS20705	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS20730	COG0640	Transcriptional regulator
GI364_RS20790	COG0789	Transcriptional regulator
GI364_RS20800	COG1733	regulation of RNA biosynthetic process
GI364_RS20810	COG0789	Transcriptional regulator
GI364_RS20820	COG0431	NADPH-dependent FMN reductase
GI364_RS20835	COG0596	Alpha beta hydrolase
GI364_RS20845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS20855	COG3973	AAA domain
GI364_RS20870	COG0400	carboxylic ester hydrolase activity
GI364_RS20875	COG0346	lactoylglutathione lyase activity
GI364_RS20880	COG1733	regulation of RNA biosynthetic process
GI364_RS20885	COG2890	protein-(glutamine-N5) methyltransferase activity
GI364_RS20890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_RS20910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS20920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GI364_RS20930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI364_RS20955	COG0598	Magnesium transport protein CorA
GI364_RS21000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS21020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS21170	COG0456	acetyltransferase
GI364_RS21180	COG0464	growth
GI364_RS21185	COG1404	Belongs to the peptidase S8 family
GI364_RS21215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI364_RS21220	COG0363	glucosamine-6-phosphate deaminase activity
GI364_RS21225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI364_RS21230	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GI364_RS21240	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS21255	COG0204	Acyl-transferase
GI364_RS21260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_RS21260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI364_RS21265	COG1309	transcriptional regulator
GI364_RS21270	COG0517	IMP dehydrogenase activity
GI364_RS21285	COG4608	Belongs to the ABC transporter superfamily
GI364_RS21290	COG0444	Belongs to the ABC transporter superfamily
GI364_RS21295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI364_RS21300	COG0601	transmembrane transport
GI364_RS21305	COG0747	negative chemotaxis
GI364_RS21310	COG1737	Transcriptional regulator
GI364_RS21320	COG0673	inositol 2-dehydrogenase activity
GI364_RS21340	COG4555	ABC transporter
GI364_RS21350	COG1937	Protein conserved in bacteria
GI364_RS21380	COG2197	response regulator
GI364_RS21395	COG1937	Protein conserved in bacteria
GI364_RS21405	COG0670	Belongs to the BI1 family
GI364_RS21415	COG4584	PFAM Integrase catalytic
GI364_RS21420	COG4974	Belongs to the 'phage' integrase family
GI364_RS21425	COG4974	Belongs to the 'phage' integrase family
GI364_RS21430	COG4974	Belongs to the 'phage' integrase family
GI364_RS21435	COG4584	PFAM Integrase catalytic
GI364_RS21440	COG1484	DNA-dependent DNA replication
GI364_RS21450	COG1733	regulation of RNA biosynthetic process
GI364_RS21495	COG1842	Phage shock protein A
GI364_RS21505	COG5002	protein histidine kinase activity
GI364_RS21510	COG0745	RESPONSE REGULATOR receiver
GI364_RS21525	COG0785	Cytochrome C biogenesis protein
GI364_RS21565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI364_RS21585	COG1937	Protein conserved in bacteria
GI364_RS21600	COG4990	cell redox homeostasis
GI364_RS21610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GI364_RS21620	COG2814	Major facilitator Superfamily
GI364_RS21630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI364_RS21630	COG0425	Belongs to the sulfur carrier protein TusA family
GI364_RS21645	COG4974	Belongs to the 'phage' integrase family
GI364_RS21665	COG0697	spore germination
GI364_RS21695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GI364_RS21700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI364_RS21710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GI364_RS21730	COG0726	polysaccharide deacetylase
GI364_RS21745	COG0489	protein tyrosine kinase activity
GI364_RS21755	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI364_RS21760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GI364_RS21765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GI364_RS21770	COG0101	tRNA pseudouridine synthase activity
GI364_RS21775	COG0203	ribosomal protein L17
GI364_RS21780	COG0202	RNA polymerase activity
GI364_RS21785	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GI364_RS21790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GI364_RS21795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GI364_RS21800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GI364_RS21805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GI364_RS21815	COG0563	adenylate kinase activity
GI364_RS21820	COG0201	protein transport
GI364_RS21825	COG0200	Binds to the 23S rRNA
GI364_RS21835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GI364_RS21840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GI364_RS21845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GI364_RS21850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GI364_RS21855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GI364_RS21860	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GI364_RS21870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GI364_RS21875	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GI364_RS21880	COG0255	Belongs to the universal ribosomal protein uL29 family
GI364_RS21885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GI364_RS21895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GI364_RS21900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GI364_RS21905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GI364_RS21910	COG0089	rRNA binding
GI364_RS21915	COG0088	Forms part of the polypeptide exit tunnel
GI364_RS21920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GI364_RS21925	COG0051	transcription antitermination factor activity, RNA binding
GI364_RS21930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GI364_RS21935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GI364_RS21940	COG0049	tRNA binding
GI364_RS21945	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GI364_RS21950	COG1358	cellular component organization or biogenesis
GI364_RS21955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GI364_RS21960	COG0085	RNA polymerase activity
GI364_RS21965	COG2813	Specifically methylates the guanine in position
GI364_RS21970	COG0222	ribosome binding
GI364_RS21975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GI364_RS21980	COG0081	regulation of translation
GI364_RS21990	COG0250	Participates in transcription elongation, termination and antitermination
GI364_RS22000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GI364_RS22015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI364_RS22020	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GI364_RS22025	COG0215	cysteine-tRNA ligase activity
GI364_RS22030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GI364_RS22035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GI364_RS22040	COG4956	integral membrane protein (PIN domain superfamily)
GI364_RS22045	COG1183	phosphatidylcholine synthase activity
GI364_RS22050	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GI364_RS22055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GI364_RS22060	COG0542	response to heat
GI364_RS22065	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GI364_RS22070	COG3880	PFAM UvrB UvrC protein
GI364_RS22080	COG1309	transcriptional regulator
GI364_RS22135	COG0151	Belongs to the GarS family
GI364_RS22145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GI364_RS22150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GI364_RS22155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GI364_RS22160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI364_RS22165	COG0047	phosphoribosylformylglycinamidine synthase activity
GI364_RS22170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI364_RS22175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GI364_RS22180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GI364_RS22205	COG0500	methyltransferase
GI364_RS22220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI364_RS22240	COG0842	Transport permease protein
GI364_RS22250	COG1131	(ABC) transporter
GI364_RS22255	COG2197	response regulator
GI364_RS22260	COG4585	Histidine kinase
GI364_RS22265	COG2252	PERMEase
GI364_RS22275	COG1305	Transglutaminase-like
GI364_RS22285	COG0714	Associated with various cellular activities
GI364_RS22295	COG0459	protein refolding
GI364_RS22300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GI364_RS22305	COG0805	protein transport
GI364_RS22310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GI364_RS22330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GI364_RS22335	COG0488	(ABC) transporter
GI364_RS22340	COG2113	Glycine betaine
GI364_RS22350	COG0517	IMP dehydrogenase activity
GI364_RS22350	COG4175	Glycine betaine
GI364_RS22355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GI364_RS22360	COG0456	acetyltransferase
GI364_RS22365	COG1214	PFAM Peptidase M22, glycoprotease
GI364_RS22370	COG0802	atpase or kinase
GI364_RS22375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GI364_RS22380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GI364_RS22405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GI364_RS22410	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GI364_RS22415	COG2337	Toxic component of a toxin-antitoxin (TA) module
GI364_RS22420	COG0864	Transcriptional regulator
GI364_RS22425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GI364_RS22435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GI364_RS22440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GI364_RS22440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GI364_RS22445	COG0736	holo-[acyl-carrier-protein] synthase activity
GI364_RS22465	COG1506	peptidase
GI364_RS22470	COG0024	Methionine aminopeptidase
GI364_RS22500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GI364_RS22510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GI364_RS22520	COG4464	protein tyrosine phosphatase activity
GI364_RS22530	COG0772	Belongs to the SEDS family
GI364_RS22540	COG1968	undecaprenyl-diphosphatase activity
GI364_RS22555	COG1609	Transcriptional regulator
GI364_RS22560	COG3833	ABC-type maltose transport systems, permease component
GI364_RS22565	COG1175	transmembrane transport
GI364_RS22570	COG2182	Extracellular solute-binding protein
GI364_RS22585	COG0531	amino acid
GI364_RS22590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI364_RS22595	COG1846	Transcriptional regulator
GI364_RS22600	COG0477	Major facilitator Superfamily
GI364_RS22610	COG1802	Transcriptional regulator
GI364_RS22625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GI364_RS22630	COG2059	Chromate
GI364_RS22640	COG2059	Chromate
GI364_RS22665	COG1012	belongs to the aldehyde dehydrogenase family
GI364_RS22690	COG1595	DNA-templated transcription, initiation
GI364_RS22695	COG0668	transmembrane transport
GI364_RS22700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GI364_RS22705	COG4988	ABC transporter
GI364_RS22710	COG2113	Glycine betaine
GI364_RS22735	COG3300	MHYT domain
GI364_RS22735	COG5001	Diguanylate cyclase
GI364_RS22740	COG1316	TRANSCRIPTIONal
GI364_RS22750	COG2814	Major facilitator Superfamily
GI364_RS22765	COG1592	Rubrerythrin
GI364_RS22840	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GI364_RS22860	COG2226	methyltransferase
GI364_RS22880	COG1136	(ABC) transporter
GI364_RS22880	COG0577	efflux transmembrane transporter activity
GI364_RS22920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GI364_RS22950	COG0494	nUDIX hydrolase
GI364_RS22970	COG1609	Transcriptional regulator
GI364_RS22975	COG1653	transport
GI364_RS22990	COG0366	Alpha amylase catalytic
GI364_RS23005	COG1984	allophanate hydrolase subunit 2
GI364_RS23015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GI364_RS23020	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GI364_RS23025	COG0489	protein tyrosine kinase activity
GI364_RS23030	COG3944	biosynthesis protein
GI364_RS23050	COG0562	UDP-galactopyranose mutase
GI364_RS23055	COG2244	polysaccharide biosynthetic process
GI364_RS23065	COG0438	transferase activity, transferring glycosyl groups
GI364_RS23085	COG0438	transferase activity, transferring glycosyl groups
GI364_RS23090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GI364_RS23095	COG1739	Uncharacterized protein family UPF0029
GI364_RS23100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GI364_RS23150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GI364_RS23155	COG4786	Flagellar basal body rod
GI364_RS23160	COG4786	Flagellar basal body rod
GI364_RS23165	COG1077	Cell shape determining protein MreB Mrl
GI364_RS23170	COG1609	Transcriptional regulator
GI364_RS23175	COG0739	heme binding
GI364_RS23180	COG2385	sporulation resulting in formation of a cellular spore
GI364_RS23185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GI364_RS23210	COG1007	ATP synthesis coupled electron transport
GI364_RS23215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_RS23220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GI364_RS23225	COG0713	ATP synthesis coupled electron transport
GI364_RS23230	COG0839	Belongs to the complex I subunit 6 family
GI364_RS23240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GI364_RS23245	COG0649	NAD binding
GI364_RS23250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_RS23255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_RS23260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GI364_RS23265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GI364_RS23270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GI364_RS23275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GI364_RS23280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GI364_RS23285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GI364_RS23290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GI364_RS23295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GI364_RS23300	COG0356	it plays a direct role in the translocation of protons across the membrane
GI364_RS23320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GI364_RS23325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GI364_RS23330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GI364_RS23340	COG0004	ammonium transporteR
GI364_RS23370	COG1595	DNA-templated transcription, initiation
GI364_RS23390	COG1683	Conserved Protein
GI364_RS23400	COG0477	Major facilitator Superfamily
GI364_RS23410	COG0702	epimerase
GI364_RS23415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_RS23420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI364_RS23425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GI364_RS23435	COG0698	ribose 5-phosphate isomerase
GI364_RS23440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_RS23445	COG1971	Probably functions as a manganese efflux pump
GI364_RS23455	COG0009	L-threonylcarbamoyladenylate synthase
GI364_RS23465	COG0436	Aminotransferase
GI364_RS23475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GI364_RS23480	COG0254	rRNA binding
GI364_RS23485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GI364_RS23490	COG1494	fructose-1,6-bisphosphatase
GI364_RS23500	COG0436	Aminotransferase
GI364_RS23505	COG1473	amidohydrolase
GI364_RS23510	COG2171	N-acyltransferase activity
GI364_RS23520	COG3246	L-lysine catabolic process to acetate
GI364_RS23525	COG1607	acyl-coa hydrolase
GI364_RS23530	COG2204	response regulator
GI364_RS23535	COG0504	CTP synthase activity
GI364_RS23540	COG3343	RNA polymerase activity
GI364_RS23545	COG1703	isobutyryl-CoA mutase activity
GI364_RS23550	COG1960	acyl-CoA dehydrogenase activity
GI364_RS23555	COG1960	acyl-CoA dehydrogenase activity
GI364_RS23560	COG1024	Enoyl-CoA hydratase
GI364_RS23565	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI364_RS23570	COG0183	Belongs to the thiolase family
GI364_RS23575	COG2181	nitrate reductase activity
GI364_RS23575	COG0247	lactate metabolic process
GI364_RS23625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI364_RS23675	COG0596	Alpha beta hydrolase
GI364_RS23680	COG2249	NAD(P)H dehydrogenase (quinone) activity
GI364_RS23715	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI364_RS23720	COG0567	Dehydrogenase, E1 component
GI364_RS23730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI364_RS23745	COG0318	PFAM AMP-dependent synthetase and ligase
GI364_RS23750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI364_RS23755	COG1131	(ABC) transporter
GI364_RS23780	COG1121	(ABC) transporter
GI364_RS23800	COG0243	molybdopterin cofactor binding
GI364_RS23810	COG5012	cobalamin binding
GI364_RS23815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GI364_RS23830	COG1509	lysine 2,3-aminomutase activity
GI364_RS23835	COG0604	alcohol dehydrogenase
GI364_RS23855	COG0010	Belongs to the arginase family
GI364_RS23860	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GI364_RS23865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI364_RS23880	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS23895	COG2843	Capsule synthesis protein
GI364_RS23900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GI364_RS23905	COG0572	uridine kinase
GI364_RS23915	COG2409	Drug exporters of the RND superfamily
GI364_RS23915	COG1033	growth of symbiont in host cell
GI364_RS23935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI364_RS23940	COG1725	Transcriptional regulator
GI364_RS23945	COG1131	(ABC) transporter
GI364_RS23965	COG5002	protein histidine kinase activity
GI364_RS23970	COG1028	Short-chain dehydrogenase reductase Sdr
GI364_RS24055	COG1484	DNA-dependent DNA replication
GI364_RS24065	COG4584	PFAM Integrase catalytic
GI364_RS24075	COG0010	Belongs to the arginase family
GI364_RS24085	COG0076	glutamate decarboxylase activity
GI364_RS24115	COG1063	alcohol dehydrogenase
GI364_RS24125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GI364_RS24130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI364_RS24135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GI364_RS24150	COG5002	protein histidine kinase activity
GI364_RS24155	COG0745	RESPONSE REGULATOR receiver
GI364_RS24165	COG0305	Participates in initiation and elongation during chromosome replication
GI364_RS24190	COG0629	single-stranded DNA binding
GI364_RS24195	COG0360	Binds together with S18 to 16S ribosomal RNA
GI364_RS24200	COG0012	GTP binding
GI364_RS24210	COG4481	Protein conserved in bacteria
GI364_RS24230	COG1811	Na channel or pump
GI364_RS24235	COG1475	DNA binding
GI364_RS24240	COG1192	Involved in chromosome partitioning
GI364_RS24245	COG1475	DNA binding
GI364_RS24255	COG0445	tRNA wobble uridine modification
GI364_RS24265	COG1847	R3H domain protein
GI364_RS24270	COG0706	membrane insertase activity
GI364_RS24275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GI364_RS24280	COG0594	ribonuclease P activity
GI364_RS24285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GI364_RS24290	COG1192	Involved in chromosome partitioning
GI364_RS24315	COG1484	DNA-dependent DNA replication
GI364_RS24340	COG0582	viral genome integration into host DNA
GI364_RS24345	COG1742	UPF0060 membrane protein
GI364_RS24365	COG0640	Transcriptional regulator
GI364_RS24370	COG1230	cation diffusion facilitator family transporter
GI364_RS24435	COG0640	Transcriptional regulator
GI364_RS24440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI364_RS24445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_RS24450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI364_RS24550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GI364_RS24650	COG3646	Phage regulatory protein
GI364_RS24650	COG3645	SOS response
GI364_RS24695	COG4974	Belongs to the 'phage' integrase family
GI364_RS24700	COG0534	Mate efflux family protein
GI364_RS24725	COG0697	spore germination
GI364_RS24745	COG4974	Belongs to the 'phage' integrase family
GI364_RS24770	COG0531	amino acid