locus-tag	class	description
J0B03_RS00015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0B03_RS00020	COG0577	efflux transmembrane transporter activity
J0B03_RS00020	COG1136	(ABC) transporter
J0B03_RS00040	COG1253	flavin adenine dinucleotide binding
J0B03_RS00050	COG0302	gtp cyclohydrolase
J0B03_RS00055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J0B03_RS00065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J0B03_RS00070	COG1418	mRNA catabolic process
J0B03_RS00095	COG1595	DNA-templated transcription, initiation
J0B03_RS00100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J0B03_RS00130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J0B03_RS00135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J0B03_RS00145	COG1132	(ABC) transporter
J0B03_RS00150	COG1132	(ABC) transporter
J0B03_RS00160	COG2816	NAD+ diphosphatase activity
J0B03_RS00175	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J0B03_RS00195	COG3585	molybdate ion transport
J0B03_RS00200	COG3426	butyrate kinase activity
J0B03_RS00205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0B03_RS00225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J0B03_RS00225	COG0674	pyruvate-flavodoxin oxidoreductase activity
J0B03_RS00240	COG0318	PFAM AMP-dependent synthetase and ligase
J0B03_RS00250	COG1342	Belongs to the UPF0251 family
J0B03_RS00270	COG1254	Belongs to the acylphosphatase family
J0B03_RS00280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J0B03_RS00290	COG0561	phosphatase activity
J0B03_RS00300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0B03_RS00305	COG0488	(ABC) transporter
J0B03_RS00315	COG2267	carboxylic ester hydrolase activity
J0B03_RS00325	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
J0B03_RS00335	COG2199	diguanylate cyclase activity
J0B03_RS00335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J0B03_RS00340	COG3706	GGDEF domain
J0B03_RS00360	COG4509	Sortase family
J0B03_RS00370	COG1496	oxidoreductase activity
J0B03_RS00380	COG1151	hydroxylamine reductase activity
J0B03_RS00390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0B03_RS00400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J0B03_RS00420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0B03_RS00430	COG1125	glycine betaine transport
J0B03_RS00430	COG0517	IMP dehydrogenase activity
J0B03_RS00440	COG1174	glycine betaine transport
J0B03_RS00465	COG1410	methionine synthase
J0B03_RS00465	COG0646	methionine synthase
J0B03_RS00475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J0B03_RS00480	COG1185	polyribonucleotide nucleotidyltransferase activity
J0B03_RS00485	COG0756	dUTP diphosphatase activity
J0B03_RS00490	COG0527	aspartate kinase activity
J0B03_RS00495	COG1968	undecaprenyl-diphosphatase activity
J0B03_RS00500	COG1674	ftsk spoiiie
J0B03_RS00505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0B03_RS00515	COG1546	Belongs to the CinA family
J0B03_RS00515	COG1058	Belongs to the CinA family
J0B03_RS00520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J0B03_RS00525	COG1418	mRNA catabolic process
J0B03_RS00530	COG1692	metallophosphoesterase
J0B03_RS00545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J0B03_RS00560	COG4974	Belongs to the 'phage' integrase family
J0B03_RS00570	COG0768	penicillin binding
J0B03_RS00585	COG0628	permease
J0B03_RS00600	COG2309	aminopeptidase activity
J0B03_RS00610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J0B03_RS00615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J0B03_RS00620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J0B03_RS00635	COG0561	phosphatase activity
J0B03_RS00640	COG0693	protein deglycase activity
J0B03_RS00650	COG1523	belongs to the glycosyl hydrolase 13 family
J0B03_RS00655	COG0058	SHG alpha-glucan phosphorylase activity
J0B03_RS00665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J0B03_RS00670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J0B03_RS00675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J0B03_RS00690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J0B03_RS00735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J0B03_RS00740	COG4966	pilus assembly protein PilW
J0B03_RS00760	COG1459	type II secretion system
J0B03_RS00770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J0B03_RS00775	COG1803	Methylglyoxal synthase
J0B03_RS00780	COG0826	peptidase U32
J0B03_RS00785	COG4122	O-methyltransferase activity
J0B03_RS00790	COG3679	Belongs to the UPF0342 family
J0B03_RS00795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0B03_RS00800	COG0735	belongs to the Fur family
J0B03_RS00805	COG3906	Belongs to the UPF0473 family
J0B03_RS00815	COG0667	Aldo Keto reductase
J0B03_RS00820	COG4472	Bacterial protein of unknown function (DUF965)
J0B03_RS00825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J0B03_RS00840	COG0301	tRNA thio-modification
J0B03_RS00865	COG0717	Belongs to the dCTP deaminase family
J0B03_RS00870	COG1193	negative regulation of DNA recombination
J0B03_RS00875	COG0826	peptidase U32
J0B03_RS00880	COG1686	Belongs to the peptidase S11 family
J0B03_RS00895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J0B03_RS00920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J0B03_RS00925	COG0196	riboflavin kinase activity
J0B03_RS00930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J0B03_RS00935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0B03_RS00940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J0B03_RS00945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J0B03_RS00945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J0B03_RS00955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J0B03_RS00960	COG0195	Participates in both transcription termination and antitermination
J0B03_RS00970	COG1234	tRNA 3'-trailer cleavage
J0B03_RS00975	COG3842	ATPase activity
J0B03_RS00980	COG1177	transmembrane transport
J0B03_RS00990	COG1285	pathogenesis
J0B03_RS00995	COG0613	PHP domain protein
J0B03_RS01000	COG2176	DNA-directed DNA polymerase activity
J0B03_RS01005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J0B03_RS01010	COG0750	zinc metalloprotease
J0B03_RS01015	COG0575	Belongs to the CDS family
J0B03_RS01020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J0B03_RS01025	COG0233	cytoplasmic translational termination
J0B03_RS01030	COG0528	UMP kinase activity
J0B03_RS01035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J0B03_RS01040	COG0052	Belongs to the universal ribosomal protein uS2 family
J0B03_RS01050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J0B03_RS01055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J0B03_RS01060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J0B03_RS01065	COG0758	DNA mediated transformation
J0B03_RS01070	COG0606	chelatase, subunit chli
J0B03_RS01075	COG0792	nuclease activity
J0B03_RS01080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J0B03_RS01085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J0B03_RS01095	COG0335	large ribosomal subunit rRNA binding
J0B03_RS01100	COG0336	Belongs to the RNA methyltransferase TrmD family
J0B03_RS01105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J0B03_RS01110	COG1837	Belongs to the UPF0109 family
J0B03_RS01115	COG0228	four-way junction DNA binding
J0B03_RS01120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J0B03_RS01125	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
J0B03_RS01130	COG0552	protein localization to endoplasmic reticulum
J0B03_RS01135	COG1196	nuclear chromosome segregation
J0B03_RS01145	COG0571	ribonuclease III activity
J0B03_RS01150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J0B03_RS01155	COG0416	fatty acid biosynthetic process
J0B03_RS01185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J0B03_RS01190	COG0742	ribosomal rna small subunit methyltransferase
J0B03_RS01195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J0B03_RS01205	COG1302	Protein conserved in bacteria
J0B03_RS01220	COG1162	GTPase activity
J0B03_RS01225	COG2815	serine threonine protein kinase
J0B03_RS01225	COG0515	serine threonine protein kinase
J0B03_RS01230	COG0631	protein serine/threonine phosphatase activity
J0B03_RS01235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J0B03_RS01240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0B03_RS01240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0B03_RS01245	COG2738	Putative neutral zinc metallopeptidase
J0B03_RS01250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J0B03_RS01255	COG0242	peptide deformylase activity
J0B03_RS01260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J0B03_RS01270	COG0194	GDP metabolic process
J0B03_RS01275	COG1561	YicC-like family, N-terminal region
J0B03_RS01285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J0B03_RS01305	COG0564	pseudouridine synthase activity
J0B03_RS01320	COG1799	cell septum assembly
J0B03_RS01325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J0B03_RS01340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J0B03_RS01345	COG1160	GTP binding
J0B03_RS01355	COG5002	protein histidine kinase activity
J0B03_RS01360	COG0745	RESPONSE REGULATOR receiver
J0B03_RS01370	COG1937	Protein conserved in bacteria
J0B03_RS01375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J0B03_RS01380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0B03_RS01385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0B03_RS01390	COG1490	D-aminoacyl-tRNA deacylase activity
J0B03_RS01395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J0B03_RS01405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J0B03_RS01405	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J0B03_RS01410	COG5416	Lipopolysaccharide assembly protein A domain
J0B03_RS01415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J0B03_RS01420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J0B03_RS01435	COG1862	Preprotein translocase
J0B03_RS01440	COG0343	queuine tRNA-ribosyltransferase activity
J0B03_RS01445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J0B03_RS01450	COG2255	four-way junction helicase activity
J0B03_RS01460	COG0217	transcriptional regulatory protein
J0B03_RS01465	COG1739	Uncharacterized protein family UPF0029
J0B03_RS01470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0B03_RS01485	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J0B03_RS01505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0B03_RS01520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J0B03_RS01540	COG0667	Aldo Keto reductase
J0B03_RS01575	COG1309	transcriptional regulator
J0B03_RS01615	COG1704	LemA family
J0B03_RS01620	COG1051	belongs to the nudix hydrolase family
J0B03_RS01630	COG0758	DNA mediated transformation
J0B03_RS01645	COG4555	ABC transporter
J0B03_RS01660	COG1797	cobyrinic acid a,c-diamide synthase activity
J0B03_RS01710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J0B03_RS01715	COG0113	porphobilinogen synthase activity
J0B03_RS01725	COG0181	hydroxymethylbilane synthase activity
J0B03_RS01730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J0B03_RS01730	COG1648	precorrin-2 dehydrogenase activity
J0B03_RS01735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J0B03_RS01740	COG1122	ATPase activity
J0B03_RS01750	COG0310	cobalt ion transport
J0B03_RS01755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J0B03_RS01765	COG1116	anion transmembrane transporter activity
J0B03_RS01770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0B03_RS01775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0B03_RS01815	COG1166	arginine decarboxylase activity
J0B03_RS01820	COG1592	Rubrerythrin
J0B03_RS01825	COG1489	DNA binding
J0B03_RS01830	COG2211	Major facilitator Superfamily
J0B03_RS01835	COG0372	Belongs to the citrate synthase family
J0B03_RS01860	COG1461	Dihydroxyacetone kinase
J0B03_RS01870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J0B03_RS01910	COG0484	heat shock protein binding
J0B03_RS01915	COG0443	Heat shock 70 kDa protein
J0B03_RS01920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J0B03_RS01925	COG1420	regulation of RNA biosynthetic process
J0B03_RS01930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0B03_RS01935	COG0481	GTPase activity
J0B03_RS01940	COG0280	phosphate acetyltransferase
J0B03_RS01945	COG1217	gtp-binding protein TYPA
J0B03_RS01960	COG0105	UTP biosynthetic process
J0B03_RS01980	COG0494	nUDIX hydrolase
J0B03_RS01990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J0B03_RS01995	COG2384	SAM-dependent methyltransferase
J0B03_RS02005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0B03_RS02010	COG0358	DNA primase activity
J0B03_RS02015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J0B03_RS02025	COG0281	malic enzyme
J0B03_RS02035	COG4942	peptidase
J0B03_RS02040	COG3069	C4-dicarboxylate transmembrane transporter activity
J0B03_RS02045	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J0B03_RS02060	COG0640	Transcriptional regulator
J0B03_RS02070	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J0B03_RS02085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0B03_RS02090	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J0B03_RS02095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J0B03_RS02105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J0B03_RS02110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0B03_RS02115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J0B03_RS02135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J0B03_RS02135	COG0539	negative regulation of cytoplasmic translation
J0B03_RS02145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J0B03_RS02150	COG2081	HI0933 family
J0B03_RS02155	COG1737	Transcriptional regulator
J0B03_RS02160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J0B03_RS02170	COG1187	pseudouridine synthase activity
J0B03_RS02175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J0B03_RS02185	COG1994	Peptidase M50
J0B03_RS02190	COG0019	diaminopimelate decarboxylase activity
J0B03_RS02200	COG0494	nUDIX hydrolase
J0B03_RS02205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J0B03_RS02210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J0B03_RS02215	COG3856	small basic protein
J0B03_RS02220	COG3879	Bacterial protein of unknown function (DUF881)
J0B03_RS02235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0B03_RS02240	COG0772	Belongs to the SEDS family
J0B03_RS02255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J0B03_RS02265	COG0768	penicillin binding
J0B03_RS02280	COG2001	Belongs to the MraZ family
J0B03_RS02285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J0B03_RS02290	COG4869	propanediol catabolic process
J0B03_RS02295	COG0497	DNA recombination
J0B03_RS02300	COG1438	arginine binding
J0B03_RS02305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J0B03_RS02310	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J0B03_RS02330	COG1570	exodeoxyribonuclease VII activity
J0B03_RS02335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J0B03_RS02340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0B03_RS02350	COG0371	Dehydrogenase
J0B03_RS02365	COG3731	PTS system glucitol sorbitol-specific IIA component
J0B03_RS02370	COG3732	PTS system glucitol sorbitol-specific
J0B03_RS02385	COG2390	Transcriptional regulator
J0B03_RS02390	COG1924	4 iron, 4 sulfur cluster binding
J0B03_RS02395	COG1070	Carbohydrate kinase
J0B03_RS02405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J0B03_RS02410	COG0072	phenylalanine-tRNA ligase activity
J0B03_RS02410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0B03_RS02415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J0B03_RS02420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0B03_RS02425	COG0569	domain protein
J0B03_RS02430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0B03_RS02445	COG2252	PERMEase
J0B03_RS02525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J0B03_RS02560	COG1854	S-ribosylhomocysteine lyase activity
J0B03_RS02565	COG0527	aspartate kinase activity
J0B03_RS02570	COG0460	homoserine dehydrogenase
J0B03_RS02590	COG0004	ammonium transporteR
J0B03_RS02600	COG2211	Major facilitator Superfamily
J0B03_RS02615	COG0493	'glutamate synthase
J0B03_RS02620	COG0067	glutamate synthase
J0B03_RS02620	COG0069	glutamate synthase activity
J0B03_RS02620	COG0070	glutamate synthase
J0B03_RS02645	COG0683	leucine binding
J0B03_RS02650	COG2070	2-Nitropropane dioxygenase
J0B03_RS02660	COG0546	phosphoglycolate phosphatase activity
J0B03_RS02665	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
J0B03_RS02670	COG2827	Endonuclease containing a URI domain
J0B03_RS02680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J0B03_RS02685	COG1509	lysine 2,3-aminomutase activity
J0B03_RS02690	COG0651	ATP synthesis coupled electron transport
J0B03_RS02700	COG2111	Na H antiporter
J0B03_RS02720	COG2212	antiporter activity
J0B03_RS02730	COG0704	Plays a role in the regulation of phosphate uptake
J0B03_RS02735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J0B03_RS02740	COG0581	inorganic phosphate transmembrane transporter activity
J0B03_RS02745	COG0573	inorganic phosphate transmembrane transporter activity
J0B03_RS02750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J0B03_RS02755	COG0531	amino acid
J0B03_RS02785	COG2205	protein histidine kinase activity
J0B03_RS02810	COG0646	methionine synthase
J0B03_RS02810	COG1410	methionine synthase
J0B03_RS02815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J0B03_RS02845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J0B03_RS02860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0B03_RS02865	COG4120	Belongs to the binding-protein-dependent transport system permease family
J0B03_RS02895	COG4166	transmembrane transport
J0B03_RS02900	COG0601	transmembrane transport
J0B03_RS02905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0B03_RS02910	COG0444	Belongs to the ABC transporter superfamily
J0B03_RS02915	COG4608	Belongs to the ABC transporter superfamily
J0B03_RS02920	COG1126	abc transporter atp-binding protein
J0B03_RS02925	COG0765	amino acid transport
J0B03_RS02940	COG4176	ABC-type proline glycine betaine transport system permease component
J0B03_RS02945	COG1116	anion transmembrane transporter activity
J0B03_RS02950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0B03_RS02955	COG1575	Belongs to the MenA family. Type 1 subfamily
J0B03_RS03000	COG0419	ATPase involved in DNA repair
J0B03_RS03005	COG0420	3'-5' exonuclease activity
J0B03_RS03045	COG1410	methionine synthase
J0B03_RS03045	COG0646	methionine synthase
J0B03_RS03060	COG2814	Major facilitator Superfamily
J0B03_RS03075	COG1918	ferrous iron import across plasma membrane
J0B03_RS03080	COG0488	(ABC) transporter
J0B03_RS03085	COG1013	pyruvate-flavodoxin oxidoreductase activity
J0B03_RS03090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J0B03_RS03090	COG0674	pyruvate-flavodoxin oxidoreductase activity
J0B03_RS03095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0B03_RS03100	COG0454	-acetyltransferase
J0B03_RS03105	COG0517	IMP dehydrogenase activity
J0B03_RS03110	COG0123	including yeast histone deacetylase and acetoin utilization protein
J0B03_RS03140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0B03_RS03175	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J0B03_RS03190	COG0765	amino acid transport
J0B03_RS03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS03200	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
J0B03_RS03205	COG0436	Aminotransferase
J0B03_RS03220	COG1104	cysteine desulfurase activity
J0B03_RS03230	COG0709	Synthesizes selenophosphate from selenide and ATP
J0B03_RS03235	COG1017	nitric oxide dioxygenase activity
J0B03_RS03235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J0B03_RS03245	COG4608	Belongs to the ABC transporter superfamily
J0B03_RS03250	COG0444	Belongs to the ABC transporter superfamily
J0B03_RS03255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0B03_RS03260	COG0601	transmembrane transport
J0B03_RS03265	COG4166	transmembrane transport
J0B03_RS03275	COG2391	methyltransferase activity
J0B03_RS03280	COG0668	transmembrane transport
J0B03_RS03285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0B03_RS03350	COG2414	aldehyde ferredoxin oxidoreductase
J0B03_RS03355	COG1691	(AIR) carboxylase
J0B03_RS03360	COG1606	tRNA processing
J0B03_RS03365	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J0B03_RS03375	COG0248	Ppx GppA phosphatase
J0B03_RS03385	COG3706	GGDEF domain
J0B03_RS03400	COG0805	protein transport
J0B03_RS03405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J0B03_RS03410	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J0B03_RS03420	COG2414	aldehyde ferredoxin oxidoreductase
J0B03_RS03445	COG2261	transglycosylase associated protein
J0B03_RS03465	COG0367	asparagine synthase
J0B03_RS03480	COG1472	Belongs to the glycosyl hydrolase 3 family
J0B03_RS03495	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS03500	COG0589	response to stress
J0B03_RS03505	COG0243	molybdopterin cofactor binding
J0B03_RS03520	COG0584	glycerophosphoryl diester phosphodiesterase
J0B03_RS03525	COG0789	Transcriptional regulator
J0B03_RS03530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J0B03_RS03535	COG1191	sigma factor activity
J0B03_RS03545	COG1525	nuclease
J0B03_RS03550	COG2508	Transcriptional regulator
J0B03_RS03560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J0B03_RS03575	COG0646	methionine synthase
J0B03_RS03575	COG1410	methionine synthase
J0B03_RS03610	COG0628	permease
J0B03_RS03625	COG1063	alcohol dehydrogenase
J0B03_RS03645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0B03_RS03660	COG3976	FMN-binding domain protein
J0B03_RS03660	COG1053	succinate dehydrogenase
J0B03_RS03665	COG3976	FMN-binding domain protein
J0B03_RS03665	COG1053	succinate dehydrogenase
J0B03_RS03670	COG1309	transcriptional regulator
J0B03_RS03675	COG0659	secondary active sulfate transmembrane transporter activity
J0B03_RS03700	COG2814	Major facilitator Superfamily
J0B03_RS03705	COG0589	response to stress
J0B03_RS03730	COG1131	(ABC) transporter
J0B03_RS03735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0B03_RS03750	COG1414	Transcriptional regulator
J0B03_RS03760	COG0800	Aldolase
J0B03_RS03775	COG1063	alcohol dehydrogenase
J0B03_RS03790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J0B03_RS03795	COG1802	Transcriptional regulator
J0B03_RS03805	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0B03_RS03810	COG0579	oxidoreductase
J0B03_RS03815	COG2188	Transcriptional regulator
J0B03_RS03840	COG1609	Transcriptional regulator
J0B03_RS03845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J0B03_RS03865	COG0673	inositol 2-dehydrogenase activity
J0B03_RS03870	COG2731	YhcH YjgK YiaL family protein
J0B03_RS03880	COG5646	InterPro IPR014922
J0B03_RS03890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J0B03_RS03945	COG3775	system Galactitol-specific IIC component
J0B03_RS03950	COG3414	Phosphotransferase system galactitol-specific IIB component
J0B03_RS03970	COG5012	cobalamin binding
J0B03_RS03980	COG1063	alcohol dehydrogenase
J0B03_RS03985	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J0B03_RS03990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J0B03_RS04000	COG2188	Transcriptional regulator
J0B03_RS04005	COG0561	phosphatase activity
J0B03_RS04035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J0B03_RS04035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J0B03_RS04045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J0B03_RS04070	COG3775	system Galactitol-specific IIC component
J0B03_RS04085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS04090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS04095	COG0697	spore germination
J0B03_RS04170	COG2801	Transposase and inactivated derivatives
J0B03_RS04185	COG3328	transposase activity
J0B03_RS04230	COG1086	Polysaccharide biosynthesis protein
J0B03_RS04250	COG2801	Transposase and inactivated derivatives
J0B03_RS04265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0B03_RS04295	COG1316	TRANSCRIPTIONal
J0B03_RS04315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J0B03_RS04320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0B03_RS04325	COG1063	alcohol dehydrogenase
J0B03_RS04330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J0B03_RS04355	COG1682	transport, permease protein
J0B03_RS04370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J0B03_RS04375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J0B03_RS04380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J0B03_RS04385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J0B03_RS04390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J0B03_RS04395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J0B03_RS04415	COG0356	it plays a direct role in the translocation of protons across the membrane
J0B03_RS04435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J0B03_RS04440	COG0698	ribose 5-phosphate isomerase
J0B03_RS04450	COG0009	L-threonylcarbamoyladenylate synthase
J0B03_RS04455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J0B03_RS04470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J0B03_RS04470	COG0517	IMP dehydrogenase activity
J0B03_RS04475	COG2309	aminopeptidase activity
J0B03_RS04525	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
J0B03_RS04530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0B03_RS04540	COG2996	Protein conserved in bacteria
J0B03_RS04545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS04550	COG0765	amino acid transport
J0B03_RS04555	COG1126	abc transporter atp-binding protein
J0B03_RS04575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0B03_RS04575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS04575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0B03_RS04580	COG1105	Belongs to the carbohydrate kinase PfkB family
J0B03_RS04585	COG1349	DNA-binding transcription factor activity
J0B03_RS04595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J0B03_RS04610	COG0346	lactoylglutathione lyase activity
J0B03_RS04620	COG0037	tRNA processing
J0B03_RS04625	COG0071	Belongs to the small heat shock protein (HSP20) family
J0B03_RS04655	COG0489	protein tyrosine kinase activity
J0B03_RS04665	COG1342	Belongs to the UPF0251 family
J0B03_RS04670	COG1126	abc transporter atp-binding protein
J0B03_RS04675	COG0765	amino acid transport
J0B03_RS04680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS04705	COG0628	permease
J0B03_RS04725	COG5012	cobalamin binding
J0B03_RS04755	COG1309	transcriptional regulator
J0B03_RS04775	COG2814	Major facilitator Superfamily
J0B03_RS04780	COG1116	anion transmembrane transporter activity
J0B03_RS04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0B03_RS04795	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0B03_RS04815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0B03_RS04835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J0B03_RS04845	COG0583	DNA-binding transcription factor activity
J0B03_RS04850	COG2391	methyltransferase activity
J0B03_RS04860	COG1115	amino acid carrier protein
J0B03_RS04875	COG0798	PFAM Bile acid sodium symporter
J0B03_RS04885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0B03_RS04890	COG2211	Major facilitator Superfamily
J0B03_RS04895	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J0B03_RS04905	COG1132	(ABC) transporter
J0B03_RS04950	COG1882	Formate acetyltransferase
J0B03_RS04975	COG1172	Belongs to the binding-protein-dependent transport system permease family
J0B03_RS04980	COG1129	ABC transporter
J0B03_RS04995	COG0205	6-phosphofructokinase activity
J0B03_RS05000	COG0205	6-phosphofructokinase activity
J0B03_RS05005	COG3275	phosphorelay sensor kinase activity
J0B03_RS05010	COG3279	Response regulator of the LytR AlgR family
J0B03_RS05020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0B03_RS05035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J0B03_RS05040	COG1053	succinate dehydrogenase
J0B03_RS05065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0B03_RS05085	COG2217	Heavy metal translocating P-type atpase
J0B03_RS05095	COG0390	transport system, permease component
J0B03_RS05100	COG1732	Glycine betaine
J0B03_RS05105	COG1174	glycine betaine transport
J0B03_RS05110	COG1125	glycine betaine transport
J0B03_RS05110	COG0517	IMP dehydrogenase activity
J0B03_RS05115	COG1174	glycine betaine transport
J0B03_RS05130	COG0671	phosphoesterase, PA-phosphatase related
J0B03_RS05135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J0B03_RS05140	COG0667	Aldo Keto reductase
J0B03_RS05170	COG0445	tRNA wobble uridine modification
J0B03_RS05200	COG0596	Alpha beta hydrolase
J0B03_RS05235	COG2801	Transposase and inactivated derivatives
J0B03_RS05250	COG0488	(ABC) transporter
J0B03_RS05255	COG1131	(ABC) transporter
J0B03_RS05260	COG0842	Transport permease protein
J0B03_RS05280	COG2207	Transcriptional regulator
J0B03_RS05280	COG3708	Transcriptional regulator
J0B03_RS05285	COG0513	Belongs to the DEAD box helicase family
J0B03_RS05290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J0B03_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS05300	COG0583	DNA-binding transcription factor activity
J0B03_RS05340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0B03_RS05340	COG0493	'glutamate synthase
J0B03_RS05350	COG3620	sequence-specific DNA binding
J0B03_RS05375	COG2801	Transposase and inactivated derivatives
J0B03_RS05400	COG1233	COG1233 Phytoene dehydrogenase and related
J0B03_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS05425	COG3177	Filamentation induced by cAMP protein fic
J0B03_RS05445	COG3328	transposase activity
J0B03_RS05465	COG5012	cobalamin binding
J0B03_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS05515	COG0210	DNA helicase
J0B03_RS05590	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
J0B03_RS05635	COG0740	serine-type endopeptidase activity
J0B03_RS05640	COG4695	Portal protein
J0B03_RS05675	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J0B03_RS05785	COG2801	Transposase and inactivated derivatives
J0B03_RS05800	COG1484	DNA-dependent DNA replication
J0B03_RS05845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J0B03_RS05855	COG1268	BioY protein
J0B03_RS05865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0B03_RS05870	COG0569	domain protein
J0B03_RS05875	COG2205	protein histidine kinase activity
J0B03_RS05880	COG0745	RESPONSE REGULATOR receiver
J0B03_RS05905	COG3475	LICD family
J0B03_RS05910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J0B03_RS05910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J0B03_RS05945	COG0438	transferase activity, transferring glycosyl groups
J0B03_RS05955	COG1215	transferase activity, transferring glycosyl groups
J0B03_RS05960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0B03_RS05965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J0B03_RS05970	COG3394	polysaccharide catabolic process
J0B03_RS05975	COG3475	LICD family
J0B03_RS05995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J0B03_RS06000	COG1615	UPF0182 protein
J0B03_RS06005	COG1827	regulation of RNA biosynthetic process
J0B03_RS06060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0B03_RS06065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J0B03_RS06070	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J0B03_RS06090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J0B03_RS06095	COG0037	tRNA processing
J0B03_RS06125	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J0B03_RS06125	COG0248	Ppx GppA phosphatase
J0B03_RS06130	COG1098	S1 RNA binding domain
J0B03_RS06140	COG0151	Belongs to the GarS family
J0B03_RS06145	COG0138	bifunctional purine biosynthesis protein purh
J0B03_RS06150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J0B03_RS06160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J0B03_RS06165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J0B03_RS06180	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J0B03_RS06185	COG0776	regulation of translation
J0B03_RS06190	COG3956	TIGRFAM MazG family protein
J0B03_RS06195	COG2244	polysaccharide biosynthetic process
J0B03_RS06205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0B03_RS06210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J0B03_RS06215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J0B03_RS06220	COG0193	aminoacyl-tRNA hydrolase activity
J0B03_RS06230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J0B03_RS06240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0B03_RS06245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0B03_RS06260	COG0653	protein targeting
J0B03_RS06265	COG1254	Belongs to the acylphosphatase family
J0B03_RS06270	COG2033	superoxide reductase activity
J0B03_RS06275	COG2270	Major facilitator Superfamily
J0B03_RS06285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J0B03_RS06290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J0B03_RS06300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J0B03_RS06305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J0B03_RS06310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J0B03_RS06320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J0B03_RS06330	COG1122	ATPase activity
J0B03_RS06340	COG0202	RNA polymerase activity
J0B03_RS06345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J0B03_RS06355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J0B03_RS06365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J0B03_RS06375	COG0024	Methionine aminopeptidase
J0B03_RS06380	COG0563	adenylate kinase activity
J0B03_RS06385	COG0201	protein transport
J0B03_RS06390	COG0200	Binds to the 23S rRNA
J0B03_RS06395	COG1841	ribosomal large subunit assembly
J0B03_RS06400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J0B03_RS06405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J0B03_RS06415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J0B03_RS06420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J0B03_RS06435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J0B03_RS06440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J0B03_RS06445	COG0255	Belongs to the universal ribosomal protein uL29 family
J0B03_RS06455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J0B03_RS06460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J0B03_RS06465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J0B03_RS06470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J0B03_RS06475	COG0089	rRNA binding
J0B03_RS06480	COG0088	Forms part of the polypeptide exit tunnel
J0B03_RS06485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J0B03_RS06490	COG0051	transcription antitermination factor activity, RNA binding
J0B03_RS06495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J0B03_RS06505	COG0049	tRNA binding
J0B03_RS06510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J0B03_RS06515	COG1358	cellular component organization or biogenesis
J0B03_RS06525	COG0085	RNA polymerase activity
J0B03_RS06530	COG0222	ribosome binding
J0B03_RS06535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J0B03_RS06540	COG0081	regulation of translation
J0B03_RS06550	COG0250	Participates in transcription elongation, termination and antitermination
J0B03_RS06555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J0B03_RS06565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J0B03_RS06590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0B03_RS06600	COG0116	Belongs to the methyltransferase superfamily
J0B03_RS06605	COG0124	histidyl-tRNA synthetase
J0B03_RS06615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J0B03_RS06620	COG1802	Transcriptional regulator
J0B03_RS06630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J0B03_RS06635	COG1074	ATP-dependent DNA helicase activity
J0B03_RS06640	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
J0B03_RS06645	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0B03_RS06650	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J0B03_RS06670	COG1464	Belongs to the NlpA lipoprotein family
J0B03_RS06675	COG2011	ABC-type metal ion transport system permease component
J0B03_RS06680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0B03_RS06685	COG1959	2 iron, 2 sulfur cluster binding
J0B03_RS06690	COG1959	2 iron, 2 sulfur cluster binding
J0B03_RS06710	COG2217	Heavy metal translocating P-type atpase
J0B03_RS06715	COG0640	Transcriptional regulator
J0B03_RS06720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J0B03_RS06725	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
J0B03_RS06745	COG0513	Belongs to the DEAD box helicase family
J0B03_RS06750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J0B03_RS06755	COG0589	response to stress
J0B03_RS06760	COG0246	Mannitol dehydrogenase
J0B03_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS06770	COG3711	transcriptional antiterminator
J0B03_RS06785	COG2003	Belongs to the UPF0758 family
J0B03_RS06790	COG1295	ribonuclease BN
J0B03_RS06815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J0B03_RS06815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J0B03_RS06830	COG2267	carboxylic ester hydrolase activity
J0B03_RS06835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J0B03_RS06855	COG2890	protein-(glutamine-N5) methyltransferase activity
J0B03_RS06860	COG0254	rRNA binding
J0B03_RS06870	COG2002	toxin-antitoxin pair type II binding
J0B03_RS06875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J0B03_RS06880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J0B03_RS06890	COG0305	Participates in initiation and elongation during chromosome replication
J0B03_RS06895	COG0359	binds to the 23S rRNA
J0B03_RS06910	COG0629	single-stranded DNA binding
J0B03_RS06915	COG0360	Binds together with S18 to 16S ribosomal RNA
J0B03_RS06920	COG4481	Protein conserved in bacteria
J0B03_RS06935	COG1475	DNA binding
J0B03_RS06940	COG1192	Involved in chromosome partitioning
J0B03_RS06950	COG0357	Ribosomal RNA small subunit methyltransferase G
J0B03_RS06955	COG0445	tRNA wobble uridine modification
J0B03_RS06960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J0B03_RS06965	COG1847	R3H domain protein
J0B03_RS06970	COG0706	membrane insertase activity
J0B03_RS06975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J0B03_RS06980	COG0594	ribonuclease P activity
J0B03_RS06990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J0B03_RS06995	COG0592	DNA-directed DNA polymerase activity
J0B03_RS07005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J0B03_RS07010	COG0187	DNA topoisomerase II activity
J0B03_RS07015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J0B03_RS07025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J0B03_RS07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS07035	COG0765	amino acid transport
J0B03_RS07045	COG1773	rubredoxin
J0B03_RS07065	COG3118	belongs to the thioredoxin family
J0B03_RS07070	COG1982	Orn Lys Arg decarboxylase major
J0B03_RS07080	COG0470	DNA polymerase III
J0B03_RS07085	COG1774	PSP1 C-terminal conserved region
J0B03_RS07090	COG2221	Nitrite and sulphite reductase 4Fe-4S
J0B03_RS07095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J0B03_RS07100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J0B03_RS07100	COG0140	phosphoribosyl-ATP diphosphatase activity
J0B03_RS07105	COG0107	imidazoleglycerol-phosphate synthase activity
J0B03_RS07110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J0B03_RS07115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J0B03_RS07125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J0B03_RS07135	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J0B03_RS07140	COG0546	phosphoglycolate phosphatase activity
J0B03_RS07145	COG0617	tRNA 3'-terminal CCA addition
J0B03_RS07150	COG1971	Probably functions as a manganese efflux pump
J0B03_RS07155	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J0B03_RS07160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J0B03_RS07165	COG0179	Fumarylacetoacetate (FAA) hydrolase
J0B03_RS07175	COG3300	MHYT domain
J0B03_RS07175	COG5001	Diguanylate cyclase
J0B03_RS07195	COG1131	(ABC) transporter
J0B03_RS07205	COG2197	response regulator
J0B03_RS07225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J0B03_RS07230	COG0432	Pfam Uncharacterised protein family UPF0047
J0B03_RS07240	COG0534	Mate efflux family protein
J0B03_RS07250	COG1132	(ABC) transporter
J0B03_RS07255	COG1132	(ABC) transporter
J0B03_RS07290	COG3153	acetyltransferase
J0B03_RS07295	COG0653	protein targeting
J0B03_RS07315	COG4658	electron transport chain
J0B03_RS07330	COG4864	UPF0365 protein
J0B03_RS07335	COG1030	water channel activity
J0B03_RS07340	COG1136	(ABC) transporter
J0B03_RS07345	COG0577	efflux transmembrane transporter activity
J0B03_RS07405	COG2190	(PTS) system
J0B03_RS07405	COG2211	Major facilitator Superfamily
J0B03_RS07460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J0B03_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS07475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J0B03_RS07535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J0B03_RS07570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J0B03_RS07580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J0B03_RS07585	COG1609	Transcriptional regulator
J0B03_RS07590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J0B03_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS07635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J0B03_RS07645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J0B03_RS07645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J0B03_RS07680	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS07715	COG0745	RESPONSE REGULATOR receiver
J0B03_RS07745	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J0B03_RS07750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J0B03_RS07750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J0B03_RS07770	COG1983	PspC domain protein
J0B03_RS07785	COG1136	(ABC) transporter
J0B03_RS07790	COG0813	purine-nucleoside phosphorylase activity
J0B03_RS07810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0B03_RS07815	COG0504	CTP synthase activity
J0B03_RS07820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J0B03_RS07825	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J0B03_RS07830	COG0287	Prephenate dehydrogenase
J0B03_RS07835	COG0084	hydrolase, TatD family'
J0B03_RS07840	COG3584	3D domain protein
J0B03_RS07845	COG2255	four-way junction helicase activity
J0B03_RS07855	COG0739	heme binding
J0B03_RS07860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J0B03_RS07865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J0B03_RS07870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J0B03_RS07880	COG3481	metal-dependent phosphohydrolase, HD sub domain
J0B03_RS07890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J0B03_RS07900	COG0028	Belongs to the TPP enzyme family
J0B03_RS07910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J0B03_RS07915	COG0473	3-isopropylmalate dehydrogenase activity
J0B03_RS07925	COG2235	arginine
J0B03_RS07930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J0B03_RS07935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0B03_RS07940	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0B03_RS07950	COG2078	PFAM AMMECR1 domain protein
J0B03_RS07950	COG3885	ferrous iron binding
J0B03_RS07980	COG0543	2 iron, 2 sulfur cluster binding
J0B03_RS07990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J0B03_RS08005	COG1959	2 iron, 2 sulfur cluster binding
J0B03_RS08015	COG1247	-acetyltransferase
J0B03_RS08020	COG3383	formate dehydrogenase (NAD+) activity
J0B03_RS08045	COG2414	aldehyde ferredoxin oxidoreductase
J0B03_RS08085	COG0521	Mo-molybdopterin cofactor biosynthetic process
J0B03_RS08095	COG0303	'Molybdopterin
J0B03_RS08100	COG1910	domain protein
J0B03_RS08105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J0B03_RS08125	COG2414	aldehyde ferredoxin oxidoreductase
J0B03_RS08155	COG1470	cell adhesion involved in biofilm formation
J0B03_RS08160	COG0006	proline dipeptidase activity
J0B03_RS08170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0B03_RS08180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J0B03_RS08190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0B03_RS08205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J0B03_RS08210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0B03_RS08220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J0B03_RS08225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J0B03_RS08230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J0B03_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS08240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J0B03_RS08250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J0B03_RS08255	COG0825	malonyl-CoA metabolic process
J0B03_RS08265	COG0439	Biotin carboxylase
J0B03_RS08275	COG0511	ligase activity, forming carbon-carbon bonds
J0B03_RS08280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J0B03_RS08295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J0B03_RS08300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J0B03_RS08315	COG1481	regulation of sporulation
J0B03_RS08325	COG0205	6-phosphofructokinase activity
J0B03_RS08340	COG5002	protein histidine kinase activity
J0B03_RS08345	COG0745	RESPONSE REGULATOR receiver
J0B03_RS08355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0B03_RS08370	COG1472	Belongs to the glycosyl hydrolase 3 family
J0B03_RS08385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0B03_RS08390	COG1120	ATPase activity
J0B03_RS08425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0B03_RS08430	COG0726	polysaccharide deacetylase
J0B03_RS08435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0B03_RS08440	COG3447	MASE1 domain protein
J0B03_RS08440	COG5001	Diguanylate cyclase
J0B03_RS08440	COG5002	protein histidine kinase activity
J0B03_RS08470	COG0535	radical SAM domain protein
J0B03_RS08480	COG0424	maF-like protein
J0B03_RS08515	COG2199	diguanylate cyclase activity
J0B03_RS08520	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
J0B03_RS08525	COG0494	nUDIX hydrolase
J0B03_RS08545	COG1882	Formate acetyltransferase
J0B03_RS08550	COG1882	Formate acetyltransferase
J0B03_RS08555	COG0583	DNA-binding transcription factor activity
J0B03_RS08560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0B03_RS08565	COG4868	Belongs to the UPF0371 family
J0B03_RS08570	COG1671	Belongs to the UPF0178 family
J0B03_RS08575	COG0288	reversible hydration of carbon dioxide
J0B03_RS08580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J0B03_RS08615	COG1917	Cupin 2, conserved barrel domain protein
J0B03_RS08615	COG4977	sequence-specific DNA binding
J0B03_RS08620	COG1063	alcohol dehydrogenase
J0B03_RS08625	COG3959	Transketolase, thiamine diphosphate binding domain
J0B03_RS08630	COG3958	Transketolase
J0B03_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS08670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0B03_RS08700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0B03_RS08700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J0B03_RS08710	COG0471	metal ion transport
J0B03_RS08710	COG0490	domain, Protein
J0B03_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
J0B03_RS08730	COG0733	neurotransmitter:sodium symporter activity
J0B03_RS08735	COG3447	MASE1 domain protein
J0B03_RS08735	COG5001	Diguanylate cyclase
J0B03_RS08735	COG5002	protein histidine kinase activity
J0B03_RS08740	COG2814	Major facilitator Superfamily
J0B03_RS08760	COG3845	ABC transporter
J0B03_RS08770	COG1079	Belongs to the binding-protein-dependent transport system permease family
J0B03_RS08775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J0B03_RS08785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J0B03_RS08790	COG1605	Chorismate mutase
J0B03_RS08790	COG0077	Prephenate dehydratase
J0B03_RS08800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J0B03_RS08805	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J0B03_RS08815	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J0B03_RS08820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J0B03_RS08825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J0B03_RS08830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS08845	COG1366	Belongs to the anti-sigma-factor antagonist family
J0B03_RS08850	COG2172	sigma factor antagonist activity
J0B03_RS08855	COG1191	sigma factor activity
J0B03_RS08860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J0B03_RS08870	COG3880	PFAM UvrB UvrC protein
J0B03_RS08875	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J0B03_RS08880	COG0542	response to heat
J0B03_RS08885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J0B03_RS08885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J0B03_RS08900	COG1741	Belongs to the pirin family
J0B03_RS08915	COG0803	Belongs to the bacterial solute-binding protein 9 family
J0B03_RS08920	COG1121	(ABC) transporter
J0B03_RS08925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J0B03_RS08950	COG2226	methyltransferase
J0B03_RS08955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J0B03_RS08960	COG1846	Transcriptional regulator
J0B03_RS08965	COG1592	Rubrerythrin
J0B03_RS08970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J0B03_RS08990	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J0B03_RS08995	COG2873	o-acetylhomoserine
J0B03_RS09005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J0B03_RS09010	COG1876	peptidase activity
J0B03_RS09030	COG0530	calcium, potassium:sodium antiporter activity
J0B03_RS09035	COG2385	sporulation resulting in formation of a cellular spore
J0B03_RS09065	COG0534	Mate efflux family protein
J0B03_RS09080	COG0426	domain, Protein
J0B03_RS09080	COG1773	rubredoxin
J0B03_RS09090	COG3118	belongs to the thioredoxin family
J0B03_RS09100	COG0484	heat shock protein binding
J0B03_RS09105	COG0542	response to heat
J0B03_RS09110	COG0598	Magnesium transport protein CorA
J0B03_RS09125	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0B03_RS09135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J0B03_RS09140	COG2233	PERMEase
J0B03_RS09155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0B03_RS09165	COG1362	aminopeptidase activity
J0B03_RS09170	COG0237	dephospho-CoA kinase activity
J0B03_RS09205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J0B03_RS09210	COG4656	Part of a membrane complex involved in electron transport
J0B03_RS09215	COG4658	electron transport chain
J0B03_RS09220	COG4659	FMN binding
J0B03_RS09225	COG4660	Part of a membrane complex involved in electron transport
J0B03_RS09230	COG4657	Part of a membrane complex involved in electron transport
J0B03_RS09235	COG2878	Part of a membrane complex involved in electron transport
J0B03_RS09235	COG1245	4Fe-4S binding domain
J0B03_RS09245	COG0424	maF-like protein
J0B03_RS09250	COG1077	Cell shape determining protein MreB Mrl
J0B03_RS09265	COG0768	penicillin binding
J0B03_RS09265	COG0768	penicillin binding
J0B03_RS09270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J0B03_RS09280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J0B03_RS09290	COG0778	Nitroreductase
J0B03_RS09300	COG2208	phosphoserine phosphatase activity
J0B03_RS09305	COG1242	4 iron, 4 sulfur cluster binding
J0B03_RS09310	COG0406	alpha-ribazole phosphatase activity
J0B03_RS09315	COG0191	fructose-bisphosphate aldolase activity
J0B03_RS09320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J0B03_RS09335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J0B03_RS09345	COG0653	protein targeting
J0B03_RS09355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J0B03_RS09360	COG2183	response to ionizing radiation
J0B03_RS09370	COG0646	methionine synthase
J0B03_RS09370	COG1410	methionine synthase
J0B03_RS09380	COG1214	PFAM Peptidase M22, glycoprotease
J0B03_RS09400	COG0482	sulfurtransferase activity
J0B03_RS09405	COG0745	RESPONSE REGULATOR receiver
J0B03_RS09410	COG5002	protein histidine kinase activity
J0B03_RS09420	COG0456	acetyltransferase
J0B03_RS09430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J0B03_RS09435	COG0488	(ABC) transporter
J0B03_RS09440	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
J0B03_RS09470	COG1811	Na channel or pump
J0B03_RS09480	COG0459	protein refolding
J0B03_RS09490	COG0517	IMP dehydrogenase activity
J0B03_RS09490	COG0516	GMP reductase activity
J0B03_RS09500	COG5002	protein histidine kinase activity
J0B03_RS09535	COG3246	L-lysine catabolic process to acetate
J0B03_RS09540	COG0183	Belongs to the thiolase family
J0B03_RS09545	COG1250	3-hydroxyacyl-CoA dehydrogenase
J0B03_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS09560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J0B03_RS09565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J0B03_RS09570	COG2204	response regulator
J0B03_RS09575	COG1307	EDD domain protein, DegV family
J0B03_RS09600	COG0431	NADPH-dependent FMN reductase
J0B03_RS09605	COG0778	Nitroreductase
J0B03_RS09615	COG0519	Catalyzes the synthesis of GMP from XMP
J0B03_RS09635	COG0745	RESPONSE REGULATOR receiver
J0B03_RS09640	COG5002	protein histidine kinase activity
J0B03_RS09660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J0B03_RS09670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J0B03_RS09675	COG0309	Hydrogenase expression formation protein (HypE)
J0B03_RS09745	COG1196	nuclear chromosome segregation
J0B03_RS09755	COG0726	polysaccharide deacetylase
J0B03_RS09765	COG1136	(ABC) transporter
J0B03_RS09770	COG0719	Fe-S assembly protein
J0B03_RS09790	COG2116	formate transmembrane transporter activity
J0B03_RS09800	COG2608	mercury ion transmembrane transporter activity
J0B03_RS09810	COG1937	Protein conserved in bacteria
J0B03_RS09825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J0B03_RS09830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J0B03_RS09840	COG5598	trimethylamine methyltransferase
J0B03_RS09850	COG5598	trimethylamine methyltransferase
J0B03_RS09855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J0B03_RS09865	COG2801	Transposase and inactivated derivatives
J0B03_RS09880	COG2005	Transcriptional regulator
J0B03_RS09900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J0B03_RS09920	COG0572	uridine kinase
J0B03_RS09945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J0B03_RS09950	COG1181	Belongs to the D-alanine--D-alanine ligase family
J0B03_RS09965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J0B03_RS09970	COG0022	dehydrogenase e1 component
J0B03_RS09980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J0B03_RS10000	COG0215	cysteine-tRNA ligase activity
J0B03_RS10005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J0B03_RS10010	COG0012	GTP binding
J0B03_RS10015	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J0B03_RS10020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J0B03_RS10025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0B03_RS10035	COG2884	Cell division ATP-binding protein ftsE
J0B03_RS10040	COG2177	Part of the ABC transporter FtsEX involved in
J0B03_RS10045	COG0739	heme binding
J0B03_RS10050	COG3409	Peptidoglycan-binding domain 1 protein
J0B03_RS10050	COG0793	Belongs to the peptidase S41A family
J0B03_RS10060	COG0386	Belongs to the glutathione peroxidase family
J0B03_RS10065	COG0698	ribose 5-phosphate isomerase
J0B03_RS10120	COG2271	Major facilitator Superfamily
J0B03_RS10130	COG5012	cobalamin binding
J0B03_RS10135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J0B03_RS10145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0B03_RS10165	COG0018	arginyl-trna synthetase
J0B03_RS10170	COG2195	Cleaves the N-terminal amino acid of tripeptides
J0B03_RS10180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J0B03_RS10185	COG1329	Transcriptional regulator
J0B03_RS10190	COG4956	integral membrane protein (PIN domain superfamily)
J0B03_RS10195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J0B03_RS10200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0B03_RS10215	COG3976	FMN-binding domain protein
J0B03_RS10215	COG1053	succinate dehydrogenase
J0B03_RS10225	COG1067	ATP-dependent peptidase activity
J0B03_RS10230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J0B03_RS10235	COG1278	Cold shock
J0B03_RS10245	COG1454	alcohol dehydrogenase
J0B03_RS10260	COG3414	Phosphotransferase system galactitol-specific IIB component
J0B03_RS10270	COG0326	Molecular chaperone. Has ATPase activity
J0B03_RS10295	COG0473	3-isopropylmalate dehydrogenase activity
J0B03_RS10300	COG0590	tRNA wobble adenosine to inosine editing
J0B03_RS10310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J0B03_RS10325	COG1131	(ABC) transporter
J0B03_RS10355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J0B03_RS10360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J0B03_RS10365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J0B03_RS10370	COG0556	nucleotide-excision repair
J0B03_RS10385	COG0544	peptidyl-prolyl cis-trans isomerase activity
J0B03_RS10390	COG0740	serine-type endopeptidase activity
J0B03_RS10395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J0B03_RS10400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J0B03_RS10405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J0B03_RS10410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J0B03_RS10430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J0B03_RS10435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J0B03_RS10450	COG1713	HD superfamily hydrolase involved in NAD metabolism
J0B03_RS10465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J0B03_RS10470	COG1283	sodium-dependent phosphate transmembrane transporter activity
J0B03_RS10480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J0B03_RS10485	COG2390	Transcriptional regulator
J0B03_RS10500	COG0149	triose-phosphate isomerase activity
J0B03_RS10505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J0B03_RS10510	COG0148	phosphopyruvate hydratase activity
J0B03_RS10515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J0B03_RS10530	COG0557	exoribonuclease II activity
J0B03_RS10535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J0B03_RS10575	COG2133	pyrroloquinoline quinone binding
J0B03_RS10590	COG1307	EDD domain protein, DegV family
J0B03_RS10600	COG0840	transmembrane signaling receptor activity
J0B03_RS10615	COG3022	response to hydroperoxide
J0B03_RS10620	COG3384	dioxygenase
J0B03_RS10645	COG2211	Major facilitator Superfamily
J0B03_RS10675	COG1732	Glycine betaine
J0B03_RS10695	COG0657	acetylesterase activity
J0B03_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
J0B03_RS10765	COG4656	Part of a membrane complex involved in electron transport
J0B03_RS10770	COG2199	diguanylate cyclase activity
J0B03_RS10780	COG1687	branched-chain amino acid
J0B03_RS10785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J0B03_RS10815	COG0322	excinuclease ABC activity
J0B03_RS10820	COG0561	phosphatase activity
J0B03_RS10825	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J0B03_RS10835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0B03_RS10840	COG1307	EDD domain protein, DegV family
J0B03_RS10860	COG0745	RESPONSE REGULATOR receiver
J0B03_RS10870	COG5002	protein histidine kinase activity
J0B03_RS10875	COG1309	transcriptional regulator
J0B03_RS10880	COG0736	holo-[acyl-carrier-protein] synthase activity
J0B03_RS10885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J0B03_RS10885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J0B03_RS10890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J0B03_RS10890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J0B03_RS10895	COG4496	protein, YerC YecD
J0B03_RS10900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J0B03_RS10905	COG0772	Belongs to the SEDS family
J0B03_RS10920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0B03_RS10930	COG0165	Argininosuccinate lyase
J0B03_RS10935	COG0137	argininosuccinate synthase activity
J0B03_RS10940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J0B03_RS10945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J0B03_RS10950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J0B03_RS10955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J0B03_RS10960	COG0505	Belongs to the CarA family
J0B03_RS10965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J0B03_RS10970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J0B03_RS10975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0B03_RS10990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J0B03_RS11005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J0B03_RS11010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J0B03_RS11015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J0B03_RS11035	COG5662	AntiSigma factor
J0B03_RS11040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0B03_RS11040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0B03_RS11050	COG3331	DNA recombination
J0B03_RS11060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J0B03_RS11065	COG5012	cobalamin binding
J0B03_RS11070	COG2188	Transcriptional regulator
J0B03_RS11080	COG1846	Transcriptional regulator
J0B03_RS11085	COG1307	EDD domain protein, DegV family
J0B03_RS11095	COG3199	ATP-NAD kinase
J0B03_RS11120	COG0436	Aminotransferase
J0B03_RS11165	COG1394	ATPase activity, coupled to movement of substances
J0B03_RS11170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J0B03_RS11180	COG1686	Belongs to the peptidase S11 family
J0B03_RS11190	COG0658	competence protein
J0B03_RS11190	COG2333	competence protein COMEC
J0B03_RS11200	COG0268	Binds directly to 16S ribosomal RNA
J0B03_RS11205	COG1605	Chorismate mutase
J0B03_RS11205	COG0077	Prephenate dehydratase
J0B03_RS11215	COG0564	pseudouridine synthase activity
J0B03_RS11220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0B03_RS11230	COG1151	hydroxylamine reductase activity
J0B03_RS11280	COG5012	cobalamin binding
J0B03_RS11290	COG0028	Belongs to the TPP enzyme family
J0B03_RS11295	COG0440	acetolactate synthase activity
J0B03_RS11315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J0B03_RS11320	COG3404	Formiminotransferase-cyclodeaminase
J0B03_RS11325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J0B03_RS11345	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J0B03_RS11370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J0B03_RS11375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J0B03_RS11380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0B03_RS11390	COG1492	cobalamin metabolic process
J0B03_RS11400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J0B03_RS11405	COG0588	phosphoglycerate mutase activity
J0B03_RS11430	COG2848	UPF0210 protein
J0B03_RS11435	COG3830	Belongs to the UPF0237 family
J0B03_RS11450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J0B03_RS11455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0B03_RS11460	COG0537	adenosine 5'-monophosphoramidase activity
J0B03_RS11465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J0B03_RS11470	COG1610	YqeY-like protein
J0B03_RS11480	COG1480	7TM receptor with intracellular HD hydrolase
J0B03_RS11490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J0B03_RS11500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J0B03_RS11505	COG1381	Involved in DNA repair and RecF pathway recombination
J0B03_RS11510	COG0423	glycine-tRNA ligase activity
J0B03_RS11515	COG0517	IMP dehydrogenase activity
J0B03_RS11520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J0B03_RS11525	COG0574	Belongs to the PEP-utilizing enzyme family
J0B03_RS11525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J0B03_RS11540	COG1132	(ABC) transporter
J0B03_RS11555	COG0426	domain, Protein
J0B03_RS11555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J0B03_RS11600	COG0514	ATP-dependent DNA helicase (RecQ)
J0B03_RS11615	COG0306	phosphate transporter
J0B03_RS11630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J0B03_RS11640	COG0393	Putative heavy-metal-binding
J0B03_RS11650	COG0697	spore germination
J0B03_RS11675	COG1695	Transcriptional regulator
J0B03_RS11715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0B03_RS11720	COG0785	Cytochrome C biogenesis protein
J0B03_RS11725	COG0726	polysaccharide deacetylase
J0B03_RS11730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS11735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0B03_RS11740	COG0765	amino acid transport
J0B03_RS11745	COG0765	amino acid transport
J0B03_RS11750	COG1126	abc transporter atp-binding protein
J0B03_RS11755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0B03_RS11760	COG0569	domain protein
J0B03_RS11770	COG0768	penicillin binding
J0B03_RS11775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J0B03_RS11780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J0B03_RS11805	COG0701	Predicted permease
J0B03_RS11815	COG1162	GTPase activity
J0B03_RS11845	COG3655	Transcriptional regulator
J0B03_RS11875	COG2226	methyltransferase
J0B03_RS11890	COG0583	DNA-binding transcription factor activity
J0B03_RS11900	COG0708	Exodeoxyribonuclease III
J0B03_RS11920	COG1132	(ABC) transporter
J0B03_RS11925	COG5012	cobalamin binding
J0B03_RS11935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0B03_RS11940	COG2239	Acts as a magnesium transporter
J0B03_RS11945	COG0745	RESPONSE REGULATOR receiver
J0B03_RS11950	COG5002	protein histidine kinase activity
J0B03_RS11955	COG0525	valine-tRNA ligase activity
J0B03_RS11970	COG0095	Lipoate-protein ligase
J0B03_RS11975	COG0527	aspartate kinase activity
J0B03_RS11980	COG2171	N-acyltransferase activity
J0B03_RS11985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J0B03_RS11995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J0B03_RS12000	COG1473	amidohydrolase
J0B03_RS12010	COG2226	methyltransferase
J0B03_RS12015	COG1278	Cold shock
J0B03_RS12020	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J0B03_RS12055	COG3655	Transcriptional regulator
J0B03_RS12065	COG0107	imidazoleglycerol-phosphate synthase activity
J0B03_RS12070	COG1309	transcriptional regulator
J0B03_RS12085	COG1473	amidohydrolase
J0B03_RS12110	COG1136	(ABC) transporter
J0B03_RS12110	COG0577	efflux transmembrane transporter activity
J0B03_RS12120	COG1136	(ABC) transporter
J0B03_RS12130	COG0321	lipoyl(octanoyl) transferase activity
J0B03_RS12135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives