locus-tag	class	description
DB29_RS00005	COG1413	lyase activity
DB29_RS00020	COG0596	Alpha beta hydrolase
DB29_RS00040	COG1595	DNA-templated transcription, initiation
DB29_RS00050	COG1131	(ABC) transporter
DB29_RS00075	COG2814	Major facilitator Superfamily
DB29_RS00085	COG1695	Transcriptional regulator
DB29_RS00090	COG3708	Transcriptional regulator
DB29_RS00090	COG2207	Transcriptional regulator
DB29_RS00095	COG0733	neurotransmitter:sodium symporter activity
DB29_RS00100	COG2151	metal-sulfur cluster biosynthetic enzyme
DB29_RS00105	COG0697	spore germination
DB29_RS00115	COG0217	transcriptional regulatory protein
DB29_RS00120	COG0708	Exodeoxyribonuclease III
DB29_RS00125	COG3048	D-serine ammonia-lyase activity
DB29_RS00130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DB29_RS00135	COG1082	Xylose isomerase domain protein TIM barrel
DB29_RS00145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DB29_RS00165	COG2329	Antibiotic biosynthesis monooxygenase
DB29_RS00170	COG0626	cystathionine gamma-synthase activity
DB29_RS00175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DB29_RS00180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS00195	COG1309	transcriptional regulator
DB29_RS00205	COG0791	NLP P60 protein
DB29_RS00205	COG1388	LysM domain
DB29_RS00215	COG2094	Belongs to the DNA glycosylase MPG family
DB29_RS00220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DB29_RS00225	COG1122	ATPase activity
DB29_RS00235	COG1011	Hydrolase
DB29_RS00240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DB29_RS00245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DB29_RS00255	COG1388	LysM domain
DB29_RS00255	COG3584	3D domain protein
DB29_RS00260	COG2226	methyltransferase
DB29_RS00265	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DB29_RS00275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DB29_RS00290	COG2153	protein acetylation
DB29_RS00300	COG1690	Belongs to the RtcB family
DB29_RS00310	COG1803	Methylglyoxal synthase
DB29_RS00315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DB29_RS00320	COG1694	Mazg nucleotide pyrophosphohydrolase
DB29_RS00325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB29_RS00330	COG2814	Major facilitator Superfamily
DB29_RS00335	COG2738	Putative neutral zinc metallopeptidase
DB29_RS00345	COG4347	Protein of unknown function (DUF1405)
DB29_RS00355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DB29_RS00360	COG0723	plastoquinol--plastocyanin reductase activity
DB29_RS00370	COG5582	Belongs to the UPF0302 family
DB29_RS00375	COG0457	Tetratricopeptide repeat
DB29_RS00380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DB29_RS00385	COG0287	Prephenate dehydrogenase
DB29_RS00390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DB29_RS00395	COG0159	tryptophan synthase activity
DB29_RS00400	COG0133	tryptophan synthase activity
DB29_RS00405	COG0135	phosphoribosylanthranilate isomerase activity
DB29_RS00410	COG0134	indole-3-glycerol-phosphate synthase activity
DB29_RS00415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DB29_RS00425	COG4401	Chorismate mutase type I
DB29_RS00430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DB29_RS00435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DB29_RS00440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DB29_RS00445	COG0105	UTP biosynthetic process
DB29_RS00450	COG0142	geranyltranstransferase activity
DB29_RS00460	COG0109	protoheme IX farnesyltransferase activity
DB29_RS00465	COG2226	methyltransferase
DB29_RS00470	COG0142	geranyltranstransferase activity
DB29_RS00480	COG0302	gtp cyclohydrolase
DB29_RS00485	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DB29_RS00505	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DB29_RS00510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DB29_RS00515	COG1160	GTP binding
DB29_RS00525	COG0539	negative regulation of cytoplasmic translation
DB29_RS00530	COG0204	Acyl-transferase
DB29_RS00535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DB29_RS00540	COG2959	enzyme of heme biosynthesis
DB29_RS00545	COG3773	Cell wall hydrolase
DB29_RS00545	COG3409	Peptidoglycan-binding domain 1 protein
DB29_RS00550	COG1410	methionine synthase
DB29_RS00550	COG0646	methionine synthase
DB29_RS00555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DB29_RS00555	COG0646	methionine synthase
DB29_RS00560	COG0626	cystathionine gamma-synthase activity
DB29_RS00565	COG2339	peptidase activity
DB29_RS00575	COG0492	ferredoxin-NADP+ reductase activity
DB29_RS00580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DB29_RS00590	COG5002	protein histidine kinase activity
DB29_RS00595	COG0745	RESPONSE REGULATOR receiver
DB29_RS00600	COG4862	establishment of competence for transformation
DB29_RS00605	COG0789	Transcriptional regulator
DB29_RS00610	COG1408	metallophosphoesterase
DB29_RS00615	COG1473	amidohydrolase
DB29_RS00625	COG0438	transferase activity, transferring glycosyl groups
DB29_RS00630	COG0438	transferase activity, transferring glycosyl groups
DB29_RS00660	COG1266	CAAX protease self-immunity
DB29_RS00665	COG0514	ATP-dependent DNA helicase (RecQ)
DB29_RS00670	COG4955	Helix-turn-helix domain
DB29_RS00680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DB29_RS00685	COG0446	pyridine nucleotide-disulphide oxidoreductase
DB29_RS00690	COG0861	Integral membrane protein TerC family
DB29_RS00700	COG1120	ATPase activity
DB29_RS00705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS00710	COG5002	protein histidine kinase activity
DB29_RS00715	COG0745	RESPONSE REGULATOR receiver
DB29_RS00720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DB29_RS00725	COG1333	cytochrome c biogenesis protein
DB29_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB29_RS00735	COG1187	pseudouridine synthase activity
DB29_RS00740	COG0700	Nucleoside recognition
DB29_RS00745	COG2715	membrane protein required for spore maturation
DB29_RS00750	COG1686	Belongs to the peptidase S11 family
DB29_RS00760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DB29_RS00775	COG2323	membrane
DB29_RS00785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DB29_RS00790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DB29_RS00795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DB29_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS00810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DB29_RS00815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DB29_RS00820	COG1547	Domain of unknown function (DUF309)
DB29_RS00825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DB29_RS00830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DB29_RS00830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DB29_RS00835	COG0307	riboflavin synthase, alpha
DB29_RS00845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DB29_RS00850	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS00855	COG2084	Dehydrogenase
DB29_RS00860	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DB29_RS00865	COG2079	MmgE PrpD family protein
DB29_RS00870	COG0372	Belongs to the citrate synthase family
DB29_RS00885	COG0583	DNA-binding transcription factor activity
DB29_RS00890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DB29_RS00895	COG0019	diaminopimelate decarboxylase activity
DB29_RS00900	COG0697	spore germination
DB29_RS00915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DB29_RS00930	COG2172	sigma factor antagonist activity
DB29_RS00940	COG1686	Belongs to the peptidase S11 family
DB29_RS00950	COG1988	membrane-bound metal-dependent
DB29_RS00965	COG2814	Major facilitator Superfamily
DB29_RS00975	COG1764	response to oxidative stress
DB29_RS00985	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DB29_RS00990	COG4974	Belongs to the 'phage' integrase family
DB29_RS01000	COG0735	belongs to the Fur family
DB29_RS01005	COG1300	Membrane
DB29_RS01010	COG0494	nUDIX hydrolase
DB29_RS01015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB29_RS01020	COG1968	undecaprenyl-diphosphatase activity
DB29_RS01025	COG1850	ribulose-bisphosphate carboxylase activity
DB29_RS01030	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DB29_RS01035	COG2190	(PTS) system
DB29_RS01040	COG1510	regulation of RNA biosynthetic process
DB29_RS01060	COG0367	asparagine synthase
DB29_RS01065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DB29_RS01070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DB29_RS01075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DB29_RS01085	COG0527	aspartate kinase activity
DB29_RS01095	COG0789	Transcriptional regulator
DB29_RS01100	COG2861	carbohydrate metabolic process
DB29_RS01115	COG0517	IMP dehydrogenase activity
DB29_RS01125	COG1728	Protein conserved in bacteria
DB29_RS01130	COG2195	Cleaves the N-terminal amino acid of tripeptides
DB29_RS01135	COG0346	lactoylglutathione lyase activity
DB29_RS01140	COG1376	ErfK ybiS ycfS ynhG family protein
DB29_RS01145	COG4129	membrane
DB29_RS01150	COG4191	Histidine kinase
DB29_RS01160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DB29_RS01165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DB29_RS01170	COG0114	fumarate hydratase activity
DB29_RS01175	COG1396	sequence-specific DNA binding
DB29_RS01180	COG1396	sequence-specific DNA binding
DB29_RS01190	COG2382	esterase
DB29_RS01195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DB29_RS01200	COG2153	protein acetylation
DB29_RS01215	COG0352	thiamine-phosphate diphosphorylase activity
DB29_RS01215	COG0351	phosphomethylpyrimidine kinase
DB29_RS01220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB29_RS01225	COG2022	thiamine diphosphate biosynthetic process
DB29_RS01235	COG0352	thiamine-phosphate diphosphorylase activity
DB29_RS01240	COG1027	Aspartate ammonia-lyase
DB29_RS01245	COG1940	carbohydrate kinase activity
DB29_RS01265	COG0697	spore germination
DB29_RS01270	COG0457	Tetratricopeptide repeat
DB29_RS01270	COG0705	Rhomboid family
DB29_RS01285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DB29_RS01295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DB29_RS01300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DB29_RS01330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DB29_RS01360	COG0704	Plays a role in the regulation of phosphate uptake
DB29_RS01375	COG4086	secreted protein
DB29_RS01380	COG2814	Major facilitator Superfamily
DB29_RS01390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DB29_RS01395	COG4709	membrane
DB29_RS01400	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DB29_RS01410	COG0735	belongs to the Fur family
DB29_RS01415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB29_RS01420	COG1121	(ABC) transporter
DB29_RS01430	COG5002	protein histidine kinase activity
DB29_RS01440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DB29_RS01445	COG0513	Belongs to the DEAD box helicase family
DB29_RS01455	COG1329	Transcriptional regulator
DB29_RS01460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DB29_RS01465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DB29_RS01470	COG2384	SAM-dependent methyltransferase
DB29_RS01475	COG2010	Cytochrome c
DB29_RS01480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DB29_RS01485	COG0358	DNA primase activity
DB29_RS01490	COG1671	Belongs to the UPF0178 family
DB29_RS01495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DB29_RS01500	COG0517	IMP dehydrogenase activity
DB29_RS01505	COG0751	glycine-tRNA ligase activity
DB29_RS01510	COG0752	glycyl-tRNA synthetase alpha subunit
DB29_RS01515	COG1381	Involved in DNA repair and RecF pathway recombination
DB29_RS01520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DB29_RS01525	COG0295	cytidine deaminase activity
DB29_RS01530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DB29_RS01535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DB29_RS01540	COG1480	7TM receptor with intracellular HD hydrolase
DB29_RS01545	COG1702	phosphate starvation-inducible protein PhoH
DB29_RS01565	COG4864	UPF0365 protein
DB29_RS01570	COG1030	water channel activity
DB29_RS01575	COG1610	YqeY-like protein
DB29_RS01580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DB29_RS01585	COG1283	sodium-dependent phosphate transmembrane transporter activity
DB29_RS01590	COG0667	Aldo Keto reductase
DB29_RS01595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DB29_RS01600	COG1301	dicarboxylic acid transport
DB29_RS01605	COG2226	methyltransferase
DB29_RS01610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DB29_RS01615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DB29_RS01620	COG2264	protein methyltransferase activity
DB29_RS01625	COG0484	heat shock protein binding
DB29_RS01630	COG0443	Heat shock 70 kDa protein
DB29_RS01635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DB29_RS01640	COG1420	regulation of RNA biosynthetic process
DB29_RS01645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DB29_RS01650	COG0481	GTPase activity
DB29_RS01660	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB29_RS01665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DB29_RS01670	COG0268	Binds directly to 16S ribosomal RNA
DB29_RS01675	COG1466	dna polymerase III delta subunit
DB29_RS01680	COG2333	competence protein COMEC
DB29_RS01680	COG0658	competence protein
DB29_RS01685	COG2131	deaminase
DB29_RS01690	COG1596	polysaccharide export
DB29_RS01690	COG1555	photosystem II stabilization
DB29_RS01695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DB29_RS01700	COG2226	methyltransferase
DB29_RS01705	COG2996	Protein conserved in bacteria
DB29_RS01710	COG0799	negative regulation of ribosome biogenesis
DB29_RS01715	COG1713	HD superfamily hydrolase involved in NAD metabolism
DB29_RS01720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DB29_RS01725	COG1534	Rna-binding protein
DB29_RS01730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DB29_RS01735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DB29_RS01740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DB29_RS01785	COG0776	regulation of translation
DB29_RS01800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DB29_RS01805	COG2223	nitrite transmembrane transporter activity
DB29_RS01810	COG0243	molybdopterin cofactor binding
DB29_RS01815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DB29_RS01820	COG2146	nitrite reductase [NAD(P)H] activity
DB29_RS01825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DB29_RS01830	COG1587	Uroporphyrinogen-III synthase
DB29_RS01830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DB29_RS01850	COG0385	Bile acid
DB29_RS01860	COG1288	antiporter activity
DB29_RS01865	COG0095	Lipoate-protein ligase
DB29_RS01875	COG0366	Alpha amylase catalytic
DB29_RS01880	COG1309	transcriptional regulator
DB29_RS01885	COG0601	transmembrane transport
DB29_RS01890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB29_RS01895	COG0444	Belongs to the ABC transporter superfamily
DB29_RS01900	COG4608	Belongs to the ABC transporter superfamily
DB29_RS01905	COG0747	negative chemotaxis
DB29_RS01920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DB29_RS01925	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DB29_RS01930	COG1793	dna ligase
DB29_RS01930	COG3285	dna ligase
DB29_RS01940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DB29_RS01945	COG0572	uridine kinase
DB29_RS01950	COG4122	O-methyltransferase activity
DB29_RS01955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DB29_RS01960	COG3906	Belongs to the UPF0473 family
DB29_RS01965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DB29_RS01970	COG4472	Bacterial protein of unknown function (DUF965)
DB29_RS01975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DB29_RS01980	COG0628	permease
DB29_RS01995	COG3881	PFAM PRC-barrel domain
DB29_RS02000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DB29_RS02010	COG0482	sulfurtransferase activity
DB29_RS02015	COG1104	cysteine desulfurase activity
DB29_RS02020	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS02025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DB29_RS02035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DB29_RS02040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DB29_RS02055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DB29_RS02060	COG0124	histidyl-tRNA synthetase
DB29_RS02065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DB29_RS02070	COG0673	inositol 2-dehydrogenase activity
DB29_RS02080	COG1609	Transcriptional regulator
DB29_RS02085	COG1490	D-aminoacyl-tRNA deacylase activity
DB29_RS02090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DB29_RS02095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DB29_RS02100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DB29_RS02100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DB29_RS02105	COG5416	Lipopolysaccharide assembly protein A domain
DB29_RS02120	COG2244	polysaccharide biosynthetic process
DB29_RS02140	COG1862	Preprotein translocase
DB29_RS02145	COG0343	queuine tRNA-ribosyltransferase activity
DB29_RS02150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DB29_RS02160	COG2255	four-way junction helicase activity
DB29_RS02165	COG0632	four-way junction helicase activity
DB29_RS02185	COG1388	LysM domain
DB29_RS02190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DB29_RS02195	COG0157	Belongs to the NadC ModD family
DB29_RS02200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DB29_RS02205	COG1104	cysteine desulfurase activity
DB29_RS02210	COG1827	regulation of RNA biosynthetic process
DB29_RS02215	COG0077	Prephenate dehydratase
DB29_RS02220	COG4492	Belongs to the UPF0735 family
DB29_RS02225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DB29_RS02230	COG3290	protein histidine kinase activity
DB29_RS02245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DB29_RS02250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB29_RS02255	COG0785	Cytochrome C biogenesis protein
DB29_RS02265	COG4473	ABC transporter
DB29_RS02270	COG1131	(ABC) transporter
DB29_RS02275	COG0537	adenosine 5'-monophosphoramidase activity
DB29_RS02280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DB29_RS02290	COG1846	Transcriptional regulator
DB29_RS02305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DB29_RS02315	COG3481	metal-dependent phosphohydrolase, HD sub domain
DB29_RS02320	COG2205	protein histidine kinase activity
DB29_RS02320	COG2770	Histidine kinase
DB29_RS02325	COG0745	RESPONSE REGULATOR receiver
DB29_RS02340	COG0561	phosphatase activity
DB29_RS02345	COG3679	Belongs to the UPF0342 family
DB29_RS02350	COG4399	Belongs to the UPF0754 family
DB29_RS02360	COG2508	Transcriptional regulator
DB29_RS02365	COG3842	ATPase activity
DB29_RS02380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DB29_RS02385	COG1024	Enoyl-CoA hydratase
DB29_RS02390	COG0511	ligase activity, forming carbon-carbon bonds
DB29_RS02395	COG0439	Biotin carboxylase
DB29_RS02400	COG1960	acyl-CoA dehydrogenase activity
DB29_RS02405	COG1704	LemA family
DB29_RS02415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS02420	COG1132	(ABC) transporter
DB29_RS02425	COG1132	(ABC) transporter
DB29_RS02430	COG2719	SpoVR family
DB29_RS02435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DB29_RS02440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DB29_RS02445	COG1489	DNA binding
DB29_RS02450	COG3153	acetyltransferase
DB29_RS02450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DB29_RS02460	COG0584	glycerophosphoryl diester phosphodiesterase
DB29_RS02465	COG0179	Fumarylacetoacetate (FAA) hydrolase
DB29_RS02470	COG0436	Aminotransferase
DB29_RS02480	COG0363	glucosamine-6-phosphate deaminase activity
DB29_RS02485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DB29_RS02490	COG2188	Transcriptional regulator
DB29_RS02495	COG0165	Argininosuccinate lyase
DB29_RS02500	COG2188	Transcriptional regulator
DB29_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS02540	COG2814	Major facilitator Superfamily
DB29_RS02550	COG2718	Belongs to the UPF0229 family
DB29_RS02565	COG2766	serine protein kinase
DB29_RS02570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB29_RS02585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DB29_RS02605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DB29_RS02620	COG0783	Belongs to the Dps family
DB29_RS02625	COG1363	Peptidase, m42
DB29_RS02635	COG1131	(ABC) transporter
DB29_RS02640	COG1725	Transcriptional regulator
DB29_RS02650	COG1131	(ABC) transporter
DB29_RS02660	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS02660	COG2207	Transcriptional regulator
DB29_RS02665	COG1621	beta-fructofuranosidase activity
DB29_RS02675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS02675	COG1263	PTS System
DB29_RS02680	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS02690	COG1966	Carbon starvation protein
DB29_RS02700	COG0471	metal ion transport
DB29_RS02705	COG1405	negative regulation of cell septum assembly
DB29_RS02705	COG3012	SEC-C Motif Domain Protein
DB29_RS02715	COG0737	Belongs to the 5'-nucleotidase family
DB29_RS02725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DB29_RS02750	COG0584	glycerophosphoryl diester phosphodiesterase
DB29_RS02765	COG1442	glycosyl transferase family 8
DB29_RS02780	COG1131	(ABC) transporter
DB29_RS02785	COG2197	response regulator
DB29_RS02790	COG4585	Histidine kinase
DB29_RS02810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DB29_RS02815	COG1733	regulation of RNA biosynthetic process
DB29_RS02825	COG2267	carboxylic ester hydrolase activity
DB29_RS02895	COG3964	amidohydrolase
DB29_RS02915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DB29_RS02945	COG1733	regulation of RNA biosynthetic process
DB29_RS02950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DB29_RS02955	COG0789	Transcriptional regulator
DB29_RS02970	COG2814	Major facilitator Superfamily
DB29_RS02975	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS02985	COG0446	pyridine nucleotide-disulphide oxidoreductase
DB29_RS02995	COG0596	Alpha beta hydrolase
DB29_RS03005	COG1846	Transcriptional regulator
DB29_RS03015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DB29_RS03020	COG2814	Major facilitator Superfamily
DB29_RS03025	COG0640	Transcriptional regulator
DB29_RS03045	COG5434	Belongs to the glycosyl hydrolase 28 family
DB29_RS03150	COG0735	belongs to the Fur family
DB29_RS03160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DB29_RS03165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DB29_RS03170	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DB29_RS03175	COG4129	membrane
DB29_RS03180	COG1132	(ABC) transporter
DB29_RS03185	COG3557	Belongs to the UPF0374 family
DB29_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS03220	COG1988	membrane-bound metal-dependent
DB29_RS03235	COG2137	regulation of response to DNA damage stimulus
DB29_RS03240	COG1090	epimerase
DB29_RS03250	COG1619	proteins homologs of microcin C7 resistance protein MccF
DB29_RS03255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DB29_RS03270	COG0445	tRNA wobble uridine modification
DB29_RS03275	COG0726	polysaccharide deacetylase
DB29_RS03285	COG1253	flavin adenine dinucleotide binding
DB29_RS03295	COG0535	radical SAM domain protein
DB29_RS03310	COG1271	oxidase subunit
DB29_RS03315	COG1294	oxidase, subunit
DB29_RS03325	COG1164	Oligoendopeptidase f
DB29_RS03330	COG0753	catalase activity
DB29_RS03340	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS03345	COG0328	RNA-DNA hybrid ribonuclease activity
DB29_RS03345	COG3341	Caulimovirus viroplasmin
DB29_RS03355	COG2002	toxin-antitoxin pair type II binding
DB29_RS03365	COG0733	neurotransmitter:sodium symporter activity
DB29_RS03370	COG1077	Cell shape determining protein MreB Mrl
DB29_RS03375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS03375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS03375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS03380	COG1105	Belongs to the carbohydrate kinase PfkB family
DB29_RS03385	COG1349	DNA-binding transcription factor activity
DB29_RS03390	COG0488	(ABC) transporter
DB29_RS03395	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DB29_RS03405	COG2188	Transcriptional regulator
DB29_RS03410	COG0366	Alpha amylase catalytic
DB29_RS03415	COG1263	PTS System
DB29_RS03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS03425	COG1649	PFAM Uncharacterised BCR, COG1649
DB29_RS03430	COG2244	polysaccharide biosynthetic process
DB29_RS03435	COG1115	amino acid carrier protein
DB29_RS03440	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DB29_RS03445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DB29_RS03460	COG1132	(ABC) transporter
DB29_RS03465	COG1132	(ABC) transporter
DB29_RS03470	COG3973	AAA domain
DB29_RS03480	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DB29_RS03485	COG3639	organic phosphonate transmembrane transporter activity
DB29_RS03490	COG3639	organic phosphonate transmembrane transporter activity
DB29_RS03495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DB29_RS03530	COG0747	negative chemotaxis
DB29_RS03535	COG4608	Belongs to the ABC transporter superfamily
DB29_RS03540	COG0444	Belongs to the ABC transporter superfamily
DB29_RS03555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DB29_RS03560	COG2391	methyltransferase activity
DB29_RS03570	COG4120	Belongs to the binding-protein-dependent transport system permease family
DB29_RS03575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DB29_RS03590	COG4208	sulfate ABC transporter
DB29_RS03600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DB29_RS03605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DB29_RS03610	COG5002	protein histidine kinase activity
DB29_RS03615	COG0277	FAD linked oxidase domain protein
DB29_RS03620	COG0385	Bile acid
DB29_RS03625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DB29_RS03635	COG0747	negative chemotaxis
DB29_RS03645	COG1396	sequence-specific DNA binding
DB29_RS03660	COG0395	ABC-type sugar transport system, permease component
DB29_RS03665	COG1175	transmembrane transport
DB29_RS03685	COG1131	(ABC) transporter
DB29_RS03715	COG1522	sequence-specific DNA binding
DB29_RS03720	COG1279	arginine transmembrane transporter activity
DB29_RS03725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS03730	COG2318	DinB family
DB29_RS03735	COG3011	Protein conserved in bacteria
DB29_RS03840	COG1280	lysine exporter protein (LysE YggA)
DB29_RS03845	COG1113	amino acid transport
DB29_RS03850	COG5577	PFAM Coat F domain
DB29_RS03855	COG2423	ornithine cyclodeaminase activity
DB29_RS03860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DB29_RS03875	COG0010	Belongs to the arginase family
DB29_RS03880	COG0745	RESPONSE REGULATOR receiver
DB29_RS03890	COG1686	Belongs to the peptidase S11 family
DB29_RS03895	COG0640	Transcriptional regulator
DB29_RS03900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DB29_RS03910	COG1131	(ABC) transporter
DB29_RS03915	COG2205	protein histidine kinase activity
DB29_RS03920	COG0745	RESPONSE REGULATOR receiver
DB29_RS03930	COG3764	Sortase (surface protein transpeptidase)
DB29_RS03940	COG3397	chitin binding
DB29_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS03955	COG3732	PTS system glucitol sorbitol-specific
DB29_RS03975	COG0246	Mannitol dehydrogenase
DB29_RS03980	COG2721	sulfolactate sulfo-lyase activity
DB29_RS03985	COG0673	inositol 2-dehydrogenase activity
DB29_RS03990	COG5578	integral membrane protein
DB29_RS04000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DB29_RS04015	COG0395	ABC-type sugar transport system, permease component
DB29_RS04020	COG4209	transmembrane transport
DB29_RS04025	COG1653	transport
DB29_RS04030	COG2207	Transcriptional regulator
DB29_RS04035	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS04035	COG2169	Transcriptional regulator
DB29_RS04040	COG3250	beta-galactosidase activity
DB29_RS04040	COG5297	Belongs to the glycosyl hydrolase family 6
DB29_RS04050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DB29_RS04065	COG0395	ABC-type sugar transport system, permease component
DB29_RS04070	COG4209	transmembrane transport
DB29_RS04075	COG4753	response regulator
DB29_RS04075	COG2207	Transcriptional regulator
DB29_RS04080	COG2972	Histidine kinase
DB29_RS04085	COG1501	Belongs to the glycosyl hydrolase 31 family
DB29_RS04095	COG1940	carbohydrate kinase activity
DB29_RS04095	COG1846	Transcriptional regulator
DB29_RS04100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DB29_RS04105	COG2721	sulfolactate sulfo-lyase activity
DB29_RS04125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DB29_RS04130	COG2207	Transcriptional regulator
DB29_RS04135	COG0179	Fumarylacetoacetate (FAA) hydrolase
DB29_RS04140	COG3340	Belongs to the peptidase S51 family
DB29_RS04150	COG0523	cobalamin synthesis protein
DB29_RS04155	COG3443	Belongs to the bacterial solute-binding protein 9 family
DB29_RS04160	COG0803	Belongs to the bacterial solute-binding protein 9 family
DB29_RS04160	COG3443	Belongs to the bacterial solute-binding protein 9 family
DB29_RS04165	COG1121	(ABC) transporter
DB29_RS04170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB29_RS04175	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS04180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB29_RS04190	COG1414	Transcriptional regulator
DB29_RS04195	COG0129	dihydroxy-acid dehydratase activity
DB29_RS04205	COG0789	Transcriptional regulator
DB29_RS04240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DB29_RS04245	COG0716	FMN binding
DB29_RS04250	COG1597	lipid kinase activity
DB29_RS04255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DB29_RS04260	COG0154	amidase activity
DB29_RS04265	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DB29_RS04270	COG2318	DinB family
DB29_RS04305	COG4851	CamS sex pheromone cAM373 precursor
DB29_RS04310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DB29_RS04315	COG0210	DNA helicase
DB29_RS04320	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DB29_RS04325	COG1120	ATPase activity
DB29_RS04330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS04335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS04355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DB29_RS04360	COG4496	protein, YerC YecD
DB29_RS04365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DB29_RS04375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DB29_RS04395	COG1510	regulation of RNA biosynthetic process
DB29_RS04440	COG1131	(ABC) transporter
DB29_RS04445	COG2197	response regulator
DB29_RS04450	COG4585	Histidine kinase
DB29_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS04475	COG1063	alcohol dehydrogenase
DB29_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS04485	COG1609	Transcriptional regulator
DB29_RS04495	COG0151	Belongs to the GarS family
DB29_RS04500	COG0138	bifunctional purine biosynthesis protein purh
DB29_RS04505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DB29_RS04515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DB29_RS04520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DB29_RS04525	COG0047	phosphoribosylformylglycinamidine synthase activity
DB29_RS04530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DB29_RS04535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DB29_RS04540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DB29_RS04545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DB29_RS04550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DB29_RS04605	COG4565	transcriptional regulatory protein
DB29_RS04610	COG3290	protein histidine kinase activity
DB29_RS04615	COG0025	NhaP-type Na H and K H
DB29_RS04620	COG1132	(ABC) transporter
DB29_RS04625	COG1132	(ABC) transporter
DB29_RS04650	COG1755	Isoprenylcysteine carboxyl methyltransferase
DB29_RS04655	COG3424	synthase
DB29_RS04660	COG0789	Transcriptional regulator
DB29_RS04665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DB29_RS04670	COG1904	glucuronate isomerase
DB29_RS04675	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DB29_RS04680	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS04685	COG1349	DNA-binding transcription factor activity
DB29_RS04690	COG2059	Chromate
DB29_RS04695	COG2059	Chromate
DB29_RS04700	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DB29_RS04705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DB29_RS04720	COG3764	Sortase (surface protein transpeptidase)
DB29_RS04740	COG1510	regulation of RNA biosynthetic process
DB29_RS04745	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS04750	COG1454	alcohol dehydrogenase
DB29_RS04755	COG2186	Transcriptional regulator
DB29_RS04760	COG1556	Lactate utilization protein
DB29_RS04765	COG1139	Iron-sulfur cluster binding protein
DB29_RS04770	COG0247	lactate metabolic process
DB29_RS04775	COG1620	l-lactate permease
DB29_RS04785	COG2124	cytochrome p450
DB29_RS04790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DB29_RS04795	COG0326	Molecular chaperone. Has ATPase activity
DB29_RS04800	COG1335	isochorismatase
DB29_RS04810	COG1476	TRANSCRIPTIONal
DB29_RS04815	COG0737	Belongs to the 5'-nucleotidase family
DB29_RS04820	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS04825	COG3829	transcription factor binding
DB29_RS04825	COG3290	protein histidine kinase activity
DB29_RS04835	COG1408	metallophosphoesterase
DB29_RS04855	COG2252	PERMEase
DB29_RS04880	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DB29_RS04885	COG1461	Dihydroxyacetone kinase
DB29_RS04890	COG2376	Dihydroxyacetone kinase
DB29_RS04915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS04920	COG0572	uridine kinase
DB29_RS04925	COG0789	Transcriptional regulator
DB29_RS04930	COG4221	oxidoreductase activity
DB29_RS04935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DB29_RS04945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DB29_RS04950	COG0577	efflux transmembrane transporter activity
DB29_RS04955	COG1136	(ABC) transporter
DB29_RS04965	COG2312	Erythromycin esterase
DB29_RS04990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DB29_RS04990	COG0519	Catalyzes the synthesis of GMP from XMP
DB29_RS04995	COG1305	Transglutaminase-like
DB29_RS05000	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DB29_RS05005	COG0714	Associated with various cellular activities
DB29_RS05015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DB29_RS05030	COG0768	penicillin binding
DB29_RS05035	COG0778	Nitroreductase
DB29_RS05045	COG4824	toxin secretion phage lysis holin
DB29_RS05085	COG0281	malic enzyme
DB29_RS05090	COG3493	citrate carrier protein
DB29_RS05095	COG4565	transcriptional regulatory protein
DB29_RS05100	COG3290	protein histidine kinase activity
DB29_RS05105	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DB29_RS05110	COG1126	abc transporter atp-binding protein
DB29_RS05115	COG0765	amino acid transport
DB29_RS05120	COG0765	amino acid transport
DB29_RS05140	COG0463	Glycosyl transferase, family 2
DB29_RS05150	COG4485	Bacterial membrane protein, YfhO
DB29_RS05165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DB29_RS05175	COG3383	formate dehydrogenase (NAD+) activity
DB29_RS05180	COG2116	formate transmembrane transporter activity
DB29_RS05185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DB29_RS05190	COG0314	molybdopterin synthase activity
DB29_RS05195	COG1763	Mo-molybdopterin cofactor biosynthetic process
DB29_RS05200	COG0303	'Molybdopterin
DB29_RS05205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DB29_RS05215	COG0746	molybdenum cofactor guanylyltransferase activity
DB29_RS05220	COG0315	cyclic pyranopterin monophosphate synthase activity
DB29_RS05225	COG2368	4-hydroxyphenylacetate
DB29_RS05230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DB29_RS05235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DB29_RS05240	COG4821	SIS domain
DB29_RS05265	COG0459	protein refolding
DB29_RS05270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DB29_RS05275	COG1266	CAAX protease self-immunity
DB29_RS05285	COG0371	Dehydrogenase
DB29_RS05290	COG1464	Belongs to the NlpA lipoprotein family
DB29_RS05295	COG2011	ABC-type metal ion transport system permease component
DB29_RS05300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DB29_RS05305	COG0805	protein transport
DB29_RS05310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DB29_RS05315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DB29_RS05320	COG0488	(ABC) transporter
DB29_RS05325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DB29_RS05330	COG0456	acetyltransferase
DB29_RS05335	COG1214	PFAM Peptidase M22, glycoprotease
DB29_RS05340	COG0802	atpase or kinase
DB29_RS05345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DB29_RS05355	COG0626	cystathionine gamma-synthase activity
DB29_RS05360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DB29_RS05365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DB29_RS05370	COG1285	pathogenesis
DB29_RS05440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS05440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS05440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS05450	COG3711	transcriptional antiterminator
DB29_RS05450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS05475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DB29_RS05480	COG1687	branched-chain amino acid
DB29_RS05485	COG5646	InterPro IPR014922
DB29_RS05525	COG0473	3-isopropylmalate dehydrogenase activity
DB29_RS05530	COG1802	Transcriptional regulator
DB29_RS05535	COG2514	catechol 2,3-dioxygenase activity
DB29_RS05540	COG2140	Oxalate decarboxylase
DB29_RS05550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DB29_RS05555	COG0640	Transcriptional regulator
DB29_RS05560	COG1329	Transcriptional regulator
DB29_RS05565	COG1278	Cold shock
DB29_RS05580	COG0662	Cupin 2, conserved barrel domain protein
DB29_RS05585	COG2226	methyltransferase
DB29_RS05590	COG4282	regulation of fungal-type cell wall biogenesis
DB29_RS05595	COG2409	Drug exporters of the RND superfamily
DB29_RS05640	COG3091	SprT-like family
DB29_RS05645	COG2183	response to ionizing radiation
DB29_RS05655	COG1191	sigma factor activity
DB29_RS05660	COG2172	sigma factor antagonist activity
DB29_RS05665	COG1366	Belongs to the anti-sigma-factor antagonist family
DB29_RS05670	COG2208	phosphoserine phosphatase activity
DB29_RS05675	COG2172	sigma factor antagonist activity
DB29_RS05680	COG1366	Belongs to the anti-sigma-factor antagonist family
DB29_RS05685	COG1366	Belongs to the anti-sigma-factor antagonist family
DB29_RS05690	COG2337	Toxic component of a toxin-antitoxin (TA) module
DB29_RS05695	COG0864	Transcriptional regulator
DB29_RS05700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DB29_RS05705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DB29_RS05710	COG0736	holo-[acyl-carrier-protein] synthase activity
DB29_RS05715	COG0705	Rhomboid family
DB29_RS05725	COG1368	sulfuric ester hydrolase activity
DB29_RS05730	COG1876	peptidase activity
DB29_RS05740	COG5578	integral membrane protein
DB29_RS05745	COG3214	Protein conserved in bacteria
DB29_RS05755	COG0673	inositol 2-dehydrogenase activity
DB29_RS05760	COG1082	Xylose isomerase domain protein TIM barrel
DB29_RS05770	COG1320	monovalent cation:proton antiporter activity
DB29_RS05775	COG2212	antiporter activity
DB29_RS05780	COG1863	multisubunit Na H antiporter MnhE subunit
DB29_RS05785	COG0651	ATP synthesis coupled electron transport
DB29_RS05790	COG1006	Multisubunit Na H antiporter MnhC subunit
DB29_RS05795	COG2111	Na H antiporter
DB29_RS05800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DB29_RS05800	COG2111	Na H antiporter
DB29_RS05805	COG2205	protein histidine kinase activity
DB29_RS05815	COG1733	regulation of RNA biosynthetic process
DB29_RS05820	COG4608	Belongs to the ABC transporter superfamily
DB29_RS05825	COG0791	NLP P60 protein
DB29_RS05830	COG1619	proteins homologs of microcin C7 resistance protein MccF
DB29_RS05835	COG4166	transmembrane transport
DB29_RS05840	COG0444	Belongs to the ABC transporter superfamily
DB29_RS05845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB29_RS05850	COG0601	transmembrane transport
DB29_RS05855	COG2362	D-Aminopeptidase
DB29_RS05860	COG4191	Histidine kinase
DB29_RS05865	COG0784	Response regulator, receiver
DB29_RS05870	COG0765	amino acid transport
DB29_RS05875	COG0765	amino acid transport
DB29_RS05880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB29_RS05890	COG2962	Rard protein
DB29_RS05895	COG2706	6-phosphogluconolactonase activity
DB29_RS05900	COG0686	Belongs to the AlaDH PNT family
DB29_RS05905	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DB29_RS05905	COG2508	Transcriptional regulator
DB29_RS05915	COG0531	amino acid
DB29_RS05920	COG1876	peptidase activity
DB29_RS05930	COG1404	Belongs to the peptidase S8 family
DB29_RS05935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DB29_RS05940	COG0596	Alpha beta hydrolase
DB29_RS05945	COG0861	Integral membrane protein TerC family
DB29_RS05955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DB29_RS05960	COG2818	Glycosylase
DB29_RS05975	COG1404	Belongs to the peptidase S8 family
DB29_RS05980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DB29_RS05990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DB29_RS06005	COG3835	regulator
DB29_RS06010	COG1929	Belongs to the glycerate kinase type-1 family
DB29_RS06025	COG0024	Methionine aminopeptidase
DB29_RS06030	COG0456	acetyltransferase
DB29_RS06035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS06050	COG1846	Transcriptional regulator
DB29_RS06060	COG2239	Acts as a magnesium transporter
DB29_RS06065	COG2197	response regulator
DB29_RS06070	COG4585	Histidine kinase
DB29_RS06075	COG3239	Fatty acid desaturase
DB29_RS06080	COG2207	Transcriptional regulator
DB29_RS06085	COG1486	melibiose metabolic process
DB29_RS06090	COG0586	Pfam SNARE associated Golgi protein
DB29_RS06095	COG1191	sigma factor activity
DB29_RS06105	COG0395	ABC-type sugar transport system, permease component
DB29_RS06110	COG4209	transmembrane transport
DB29_RS06115	COG4753	response regulator
DB29_RS06115	COG2207	Transcriptional regulator
DB29_RS06120	COG2972	Histidine kinase
DB29_RS06135	COG2223	nitrite transmembrane transporter activity
DB29_RS06140	COG2197	response regulator
DB29_RS06155	COG2181	nitrate reductase activity
DB29_RS06165	COG1140	nitrate reductase beta subunit
DB29_RS06170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DB29_RS06175	COG2195	Cleaves the N-terminal amino acid of tripeptides
DB29_RS06180	COG1263	PTS System
DB29_RS06180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS06180	COG2190	(PTS) system
DB29_RS06185	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DB29_RS06190	COG1737	Transcriptional regulator
DB29_RS06210	COG1136	(ABC) transporter
DB29_RS06340	COG1511	domain protein
DB29_RS06345	COG1674	ftsk spoiiie
DB29_RS06350	COG4499	WXG100 protein secretion system (Wss), protein YukC
DB29_RS06360	COG4842	Belongs to the WXG100 family
DB29_RS06365	COG0395	ABC-type sugar transport system, permease component
DB29_RS06370	COG1175	transmembrane transport
DB29_RS06385	COG1119	ATPase activity
DB29_RS06390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB29_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS06400	COG0443	Heat shock 70 kDa protein
DB29_RS06405	COG2214	Heat shock protein DnaJ domain protein
DB29_RS06410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DB29_RS06415	COG3457	Alanine racemase
DB29_RS06420	COG0626	cystathionine gamma-synthase activity
DB29_RS06425	COG1735	metal-dependent hydrolase with the TIM-barrel fold
DB29_RS06455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DB29_RS06460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS06465	COG3290	protein histidine kinase activity
DB29_RS06470	COG4565	transcriptional regulatory protein
DB29_RS06475	COG2851	Citrate transporter
DB29_RS06500	COG2610	gluconate transmembrane transporter activity
DB29_RS06505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DB29_RS06510	COG3395	kinase activity
DB29_RS06515	COG1349	DNA-binding transcription factor activity
DB29_RS06520	COG0697	spore germination
DB29_RS06555	COG3844	kynureninase activity
DB29_RS06560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DB29_RS06565	COG2271	Major facilitator Superfamily
DB29_RS06570	COG5294	Protein conserved in bacteria
DB29_RS06585	COG2188	Transcriptional regulator
DB29_RS06590	COG3394	polysaccharide catabolic process
DB29_RS06595	COG1486	melibiose metabolic process
DB29_RS06600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS06605	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB29_RS06610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS06615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DB29_RS06625	COG0798	PFAM Bile acid sodium symporter
DB29_RS06630	COG2814	Major facilitator Superfamily
DB29_RS06640	COG0163	prenyltransferase activity
DB29_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS06650	COG1312	Catalyzes the dehydration of D-mannonate
DB29_RS06655	COG1063	alcohol dehydrogenase
DB29_RS06660	COG1053	succinate dehydrogenase
DB29_RS06665	COG0473	3-isopropylmalate dehydrogenase activity
DB29_RS06670	COG0583	DNA-binding transcription factor activity
DB29_RS06695	COG2188	Transcriptional regulator
DB29_RS06700	COG1131	(ABC) transporter
DB29_RS06710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DB29_RS06715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DB29_RS06730	COG1587	Uroporphyrinogen-III synthase
DB29_RS06730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DB29_RS06735	COG0529	Catalyzes the synthesis of activated sulfate
DB29_RS06740	COG0306	phosphate transporter
DB29_RS06745	COG2046	Belongs to the sulfate adenylyltransferase family
DB29_RS06750	COG0175	sulfate reduction
DB29_RS06760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DB29_RS06780	COG1802	Transcriptional regulator
DB29_RS06795	COG1116	anion transmembrane transporter activity
DB29_RS06800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS06805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS06810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DB29_RS06815	COG0431	NADPH-dependent FMN reductase
DB29_RS06825	COG2258	MOSC domain
DB29_RS06850	COG0318	PFAM AMP-dependent synthetase and ligase
DB29_RS06865	COG1942	4-Oxalocrotonate Tautomerase
DB29_RS06870	COG0477	Major facilitator Superfamily
DB29_RS06880	COG4126	flavin adenine dinucleotide binding
DB29_RS06905	COG2508	Transcriptional regulator
DB29_RS06910	COG0673	inositol 2-dehydrogenase activity
DB29_RS06920	COG1940	carbohydrate kinase activity
DB29_RS06930	COG1070	Carbohydrate kinase
DB29_RS06935	COG2115	Belongs to the xylose isomerase family
DB29_RS06940	COG1414	Transcriptional regulator
DB29_RS06945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS06955	COG4608	Belongs to the ABC transporter superfamily
DB29_RS06960	COG0444	Belongs to the ABC transporter superfamily
DB29_RS06975	COG0747	negative chemotaxis
DB29_RS06980	COG1228	amidohydrolase
DB29_RS06985	COG1228	amidohydrolase
DB29_RS07010	COG0395	ABC-type sugar transport system, permease component
DB29_RS07015	COG4209	transmembrane transport
DB29_RS07025	COG3507	Belongs to the glycosyl hydrolase 43 family
DB29_RS07030	COG0662	Cupin 2, conserved barrel domain protein
DB29_RS07030	COG2207	Transcriptional regulator
DB29_RS07035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DB29_RS07040	COG2011	ABC-type metal ion transport system permease component
DB29_RS07045	COG1464	Belongs to the NlpA lipoprotein family
DB29_RS07050	COG1473	amidohydrolase
DB29_RS07060	COG2084	Dehydrogenase
DB29_RS07065	COG2610	gluconate transmembrane transporter activity
DB29_RS07070	COG1737	Transcriptional regulator
DB29_RS07090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DB29_RS07095	COG2186	Transcriptional regulator
DB29_RS07100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DB29_RS07110	COG4145	pantothenate transmembrane transporter activity
DB29_RS07150	COG0710	3-dehydroquinate dehydratase activity
DB29_RS07160	COG0655	NAD(P)H dehydrogenase (quinone) activity
DB29_RS07170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB29_RS07185	COG0745	RESPONSE REGULATOR receiver
DB29_RS07190	COG2205	protein histidine kinase activity
DB29_RS07210	COG4948	Mandelate Racemase Muconate Lactonizing
DB29_RS07220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB29_RS07230	COG2755	lipolytic protein G-D-S-L family
DB29_RS07235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DB29_RS07270	COG0438	transferase activity, transferring glycosyl groups
DB29_RS07285	COG0438	transferase activity, transferring glycosyl groups
DB29_RS07315	COG2226	methyltransferase
DB29_RS07325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DB29_RS07330	COG0535	radical SAM domain protein
DB29_RS07350	COG3212	peptidase
DB29_RS07355	COG3212	peptidase
DB29_RS07360	COG5002	protein histidine kinase activity
DB29_RS07360	COG3850	Histidine kinase
DB29_RS07365	COG0745	RESPONSE REGULATOR receiver
DB29_RS07370	COG4821	SIS domain
DB29_RS07375	COG2188	Transcriptional regulator
DB29_RS07405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS07405	COG3711	transcriptional antiterminator
DB29_RS07410	COG2723	6-phospho-beta-galactosidase activity
DB29_RS07415	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB29_RS07420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS07425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS07430	COG1357	PFAM Pentapeptide repeats (8 copies)
DB29_RS07445	COG2807	transmembrane transport
DB29_RS07455	COG2186	Transcriptional regulator
DB29_RS07460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB29_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS07485	COG1312	Catalyzes the dehydration of D-mannonate
DB29_RS07530	COG0840	transmembrane signaling receptor activity
DB29_RS07540	COG2851	Citrate transporter
DB29_RS07555	COG3290	protein histidine kinase activity
DB29_RS07555	COG3829	transcription factor binding
DB29_RS07560	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DB29_RS07565	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DB29_RS07570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS07580	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS07585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS07585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS07590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS07595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS07595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS07595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS07600	COG0191	fructose-bisphosphate aldolase activity
DB29_RS07605	COG3711	transcriptional antiterminator
DB29_RS07610	COG0246	Mannitol dehydrogenase
DB29_RS07615	COG2721	sulfolactate sulfo-lyase activity
DB29_RS07620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DB29_RS07630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DB29_RS07635	COG1063	alcohol dehydrogenase
DB29_RS07645	COG1653	transport
DB29_RS07650	COG1175	transmembrane transport
DB29_RS07665	COG2873	o-acetylhomoserine
DB29_RS07670	COG2323	membrane
DB29_RS07675	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DB29_RS07680	COG0673	inositol 2-dehydrogenase activity
DB29_RS07685	COG0191	fructose-bisphosphate aldolase activity
DB29_RS07690	COG0673	inositol 2-dehydrogenase activity
DB29_RS07695	COG1082	Xylose isomerase domain protein TIM barrel
DB29_RS07700	COG3962	Belongs to the TPP enzyme family
DB29_RS07705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB29_RS07710	COG3718	enzyme involved in inositol metabolism
DB29_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS07720	COG1349	DNA-binding transcription factor activity
DB29_RS07725	COG2814	Major facilitator Superfamily
DB29_RS07730	COG1309	transcriptional regulator
DB29_RS07735	COG2076	Multidrug Resistance protein
DB29_RS07740	COG2076	Multidrug Resistance protein
DB29_RS07745	COG3279	Response regulator of the LytR AlgR family
DB29_RS07765	COG1131	(ABC) transporter
DB29_RS07770	COG1486	melibiose metabolic process
DB29_RS07775	COG4214	carbohydrate transport
DB29_RS07780	COG1129	ABC transporter
DB29_RS07785	COG4213	ABC transporter substrate-binding protein
DB29_RS07790	COG2160	L-arabinose isomerase activity
DB29_RS07795	COG1069	ribulokinase activity
DB29_RS07805	COG0371	Dehydrogenase
DB29_RS07810	COG0647	UMP catabolic process
DB29_RS07815	COG2207	Transcriptional regulator
DB29_RS07825	COG5578	integral membrane protein
DB29_RS07830	COG0395	ABC-type sugar transport system, permease component
DB29_RS07835	COG1175	transmembrane transport
DB29_RS07850	COG0395	ABC-type sugar transport system, permease component
DB29_RS07855	COG1175	transmembrane transport
DB29_RS07865	COG3401	FG-GAP repeat protein
DB29_RS07880	COG0745	RESPONSE REGULATOR receiver
DB29_RS07885	COG5002	protein histidine kinase activity
DB29_RS07895	COG0395	ABC-type sugar transport system, permease component
DB29_RS07900	COG1175	transmembrane transport
DB29_RS07905	COG1653	transport
DB29_RS07910	COG4753	response regulator
DB29_RS07910	COG2207	Transcriptional regulator
DB29_RS07915	COG2972	Histidine kinase
DB29_RS07935	COG0673	inositol 2-dehydrogenase activity
DB29_RS07940	COG2207	Transcriptional regulator
DB29_RS07945	COG2814	Major facilitator Superfamily
DB29_RS07950	COG3254	rhamnose metabolic process
DB29_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS07955	COG3347	Dehydrogenase
DB29_RS07960	COG4806	L-rhamnose isomerase
DB29_RS07960	COG1070	Carbohydrate kinase
DB29_RS07975	COG0010	Belongs to the arginase family
DB29_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS08000	COG0726	polysaccharide deacetylase
DB29_RS08005	COG0673	inositol 2-dehydrogenase activity
DB29_RS08020	COG0395	ABC-type sugar transport system, permease component
DB29_RS08025	COG4209	transmembrane transport
DB29_RS08030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DB29_RS08050	COG0584	glycerophosphoryl diester phosphodiesterase
DB29_RS08055	COG1653	transport
DB29_RS08060	COG0395	ABC-type sugar transport system, permease component
DB29_RS08065	COG1175	transmembrane transport
DB29_RS08070	COG3842	ATPase activity
DB29_RS08075	COG0584	glycerophosphoryl diester phosphodiesterase
DB29_RS08080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DB29_RS08080	COG1017	nitric oxide dioxygenase activity
DB29_RS08085	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS08135	COG0457	Tetratricopeptide repeat
DB29_RS08140	COG0183	Belongs to the thiolase family
DB29_RS08145	COG0318	PFAM AMP-dependent synthetase and ligase
DB29_RS08150	COG0318	PFAM AMP-dependent synthetase and ligase
DB29_RS08160	COG3842	ATPase activity
DB29_RS08165	COG0395	ABC-type sugar transport system, permease component
DB29_RS08170	COG1175	transmembrane transport
DB29_RS08185	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS08190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DB29_RS08195	COG0456	acetyltransferase
DB29_RS08205	COG0697	spore germination
DB29_RS08210	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS08215	COG1454	alcohol dehydrogenase
DB29_RS08220	COG2066	Belongs to the glutaminase family
DB29_RS08225	COG2610	gluconate transmembrane transporter activity
DB29_RS08235	COG3290	protein histidine kinase activity
DB29_RS08235	COG3829	transcription factor binding
DB29_RS08250	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DB29_RS08270	COG0395	ABC-type sugar transport system, permease component
DB29_RS08275	COG1175	transmembrane transport
DB29_RS08280	COG1940	carbohydrate kinase activity
DB29_RS08285	COG2723	6-phospho-beta-galactosidase activity
DB29_RS08290	COG1609	Transcriptional regulator
DB29_RS08300	COG1263	PTS System
DB29_RS08300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS08305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DB29_RS08325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DB29_RS08330	COG1737	Transcriptional regulator
DB29_RS08335	COG1132	(ABC) transporter
DB29_RS08340	COG0789	Transcriptional regulator
DB29_RS08345	COG1609	Transcriptional regulator
DB29_RS08380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DB29_RS08380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DB29_RS08385	COG0628	permease
DB29_RS08390	COG1528	Iron-storage protein
DB29_RS08405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DB29_RS08410	COG2267	carboxylic ester hydrolase activity
DB29_RS08415	COG0569	domain protein
DB29_RS08420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DB29_RS08430	COG1051	belongs to the nudix hydrolase family
DB29_RS08450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS08455	COG0697	spore germination
DB29_RS08465	COG0180	Tryptophanyl-tRNA synthetase
DB29_RS08470	COG2226	methyltransferase
DB29_RS08485	COG2072	flavoprotein involved in K transport
DB29_RS08525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DB29_RS08545	COG1136	(ABC) transporter
DB29_RS08555	COG2814	Major facilitator Superfamily
DB29_RS08560	COG1309	transcriptional regulator
DB29_RS08570	COG0745	RESPONSE REGULATOR receiver
DB29_RS08575	COG0577	efflux transmembrane transporter activity
DB29_RS08580	COG1819	glycosyl
DB29_RS08585	COG1396	sequence-specific DNA binding
DB29_RS08600	COG2207	Transcriptional regulator
DB29_RS08600	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS08605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DB29_RS08615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DB29_RS08625	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DB29_RS08630	COG5662	AntiSigma factor
DB29_RS08635	COG1595	DNA-templated transcription, initiation
DB29_RS08685	COG0747	negative chemotaxis
DB29_RS08690	COG2755	lipolytic protein G-D-S-L family
DB29_RS08695	COG1063	alcohol dehydrogenase
DB29_RS08730	COG3290	protein histidine kinase activity
DB29_RS08730	COG3829	transcription factor binding
DB29_RS08735	COG4948	Mandelate Racemase Muconate Lactonizing
DB29_RS08745	COG0789	Transcriptional regulator
DB29_RS08765	COG0789	Transcriptional regulator
DB29_RS08770	COG2226	methyltransferase
DB29_RS08810	COG0726	polysaccharide deacetylase
DB29_RS08845	COG0489	protein tyrosine kinase activity
DB29_RS08850	COG1263	PTS System
DB29_RS08850	COG2190	(PTS) system
DB29_RS08850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS08855	COG3711	transcriptional antiterminator
DB29_RS08860	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB29_RS08880	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DB29_RS08905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DB29_RS08910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DB29_RS08915	COG0101	tRNA pseudouridine synthase activity
DB29_RS08930	COG1122	ATPase activity
DB29_RS08935	COG0203	ribosomal protein L17
DB29_RS08940	COG0202	RNA polymerase activity
DB29_RS08945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DB29_RS08950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DB29_RS08955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DB29_RS08960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DB29_RS08965	COG0024	Methionine aminopeptidase
DB29_RS08970	COG0563	adenylate kinase activity
DB29_RS08975	COG0201	protein transport
DB29_RS08980	COG0200	Binds to the 23S rRNA
DB29_RS08985	COG1841	ribosomal large subunit assembly
DB29_RS08990	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DB29_RS08995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DB29_RS09000	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DB29_RS09005	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DB29_RS09010	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DB29_RS09015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DB29_RS09020	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DB29_RS09025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DB29_RS09030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DB29_RS09035	COG0255	Belongs to the universal ribosomal protein uL29 family
DB29_RS09040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DB29_RS09045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DB29_RS09050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DB29_RS09055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DB29_RS09060	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DB29_RS09065	COG0089	rRNA binding
DB29_RS09070	COG0088	Forms part of the polypeptide exit tunnel
DB29_RS09075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DB29_RS09080	COG0051	transcription antitermination factor activity, RNA binding
DB29_RS09085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DB29_RS09090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DB29_RS09095	COG0049	tRNA binding
DB29_RS09100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DB29_RS09105	COG1358	cellular component organization or biogenesis
DB29_RS09110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DB29_RS09115	COG0085	RNA polymerase activity
DB29_RS09120	COG2813	Specifically methylates the guanine in position
DB29_RS09125	COG0222	ribosome binding
DB29_RS09130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DB29_RS09135	COG0081	regulation of translation
DB29_RS09140	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DB29_RS09145	COG0250	Participates in transcription elongation, termination and antitermination
DB29_RS09150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DB29_RS09160	COG3688	RNA-binding protein containing a PIN domain
DB29_RS09165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DB29_RS09175	COG0215	cysteine-tRNA ligase activity
DB29_RS09180	COG1045	serine acetyltransferase
DB29_RS09185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DB29_RS09190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DB29_RS09195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DB29_RS09200	COG4956	integral membrane protein (PIN domain superfamily)
DB29_RS09205	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DB29_RS09210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DB29_RS09215	COG0542	response to heat
DB29_RS09220	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DB29_RS09225	COG3880	PFAM UvrB UvrC protein
DB29_RS09310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DB29_RS09315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DB29_RS09320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DB29_RS09325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DB29_RS09330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DB29_RS09335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DB29_RS09340	COG0512	Glutamine amidotransferase of anthranilate synthase
DB29_RS09345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DB29_RS09350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DB29_RS09355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DB29_RS09360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DB29_RS09375	COG0037	tRNA processing
DB29_RS09380	COG0515	serine threonine protein kinase
DB29_RS09385	COG2304	oxidoreductase activity
DB29_RS09390	COG2208	phosphoserine phosphatase activity
DB29_RS09395	COG2851	Citrate transporter
DB29_RS09405	COG1098	S1 RNA binding domain
DB29_RS09430	COG0492	ferredoxin-NADP+ reductase activity
DB29_RS09435	COG1247	-acetyltransferase
DB29_RS09440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DB29_RS09445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DB29_RS09450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DB29_RS09455	COG3956	TIGRFAM MazG family protein
DB29_RS09460	COG2244	polysaccharide biosynthetic process
DB29_RS09470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DB29_RS09480	COG2002	toxin-antitoxin pair type II binding
DB29_RS09485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DB29_RS09495	COG0193	aminoacyl-tRNA hydrolase activity
DB29_RS09500	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DB29_RS09505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DB29_RS09510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DB29_RS09515	COG2088	sporulation resulting in formation of a cellular spore
DB29_RS09520	COG0251	oxidation-reduction process
DB29_RS09525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DB29_RS09530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DB29_RS09540	COG4466	Protein conserved in bacteria
DB29_RS09550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DB29_RS09555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DB29_RS09560	COG3584	3D domain protein
DB29_RS09560	COG3583	domain protein
DB29_RS09565	COG0084	hydrolase, TatD family'
DB29_RS09580	COG0488	(ABC) transporter
DB29_RS09595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DB29_RS09595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DB29_RS09610	COG2002	toxin-antitoxin pair type II binding
DB29_RS09615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DB29_RS09620	COG2827	Endonuclease containing a URI domain
DB29_RS09625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DB29_RS09630	COG4467	Involved in initiation control of chromosome replication
DB29_RS09635	COG1774	PSP1 C-terminal conserved region
DB29_RS09640	COG0470	DNA polymerase III
DB29_RS09645	COG3870	Protein conserved in bacteria
DB29_RS09650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DB29_RS09655	COG1982	Orn Lys Arg decarboxylase major
DB29_RS09670	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS09680	COG2204	response regulator
DB29_RS09720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DB29_RS09725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DB29_RS09730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DB29_RS09740	COG0740	serine-type endopeptidase activity
DB29_RS09745	COG0590	tRNA wobble adenosine to inosine editing
DB29_RS09770	COG0444	Belongs to the ABC transporter superfamily
DB29_RS09775	COG4608	Belongs to the ABC transporter superfamily
DB29_RS09785	COG0765	amino acid transport
DB29_RS09790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB29_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS09820	COG0006	proline dipeptidase activity
DB29_RS09840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DB29_RS09845	COG3829	transcription factor binding
DB29_RS09850	COG2508	Transcriptional regulator
DB29_RS09855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DB29_RS09860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DB29_RS09870	COG0517	IMP dehydrogenase activity
DB29_RS09870	COG0516	GMP reductase activity
DB29_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS09910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DB29_RS09915	COG0187	DNA topoisomerase II activity
DB29_RS09925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DB29_RS09930	COG2501	S4 domain
DB29_RS09935	COG0592	DNA-directed DNA polymerase activity
DB29_RS09940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DB29_RS09945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DB29_RS09950	COG0594	ribonuclease P activity
DB29_RS09955	COG0706	membrane insertase activity
DB29_RS09960	COG1847	R3H domain protein
DB29_RS09965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DB29_RS09970	COG0445	tRNA wobble uridine modification
DB29_RS09975	COG0357	Ribosomal RNA small subunit methyltransferase G
DB29_RS09980	COG1475	DNA binding
DB29_RS09985	COG1192	Involved in chromosome partitioning
DB29_RS09990	COG1475	DNA binding
DB29_RS09995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DB29_RS10005	COG3949	Membrane
DB29_RS10010	COG4481	Protein conserved in bacteria
DB29_RS10015	COG0012	GTP binding
DB29_RS10020	COG0360	Binds together with S18 to 16S ribosomal RNA
DB29_RS10025	COG0629	single-stranded DNA binding
DB29_RS10030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DB29_RS10040	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DB29_RS10045	COG0359	binds to the 23S rRNA
DB29_RS10050	COG0305	Participates in initiation and elongation during chromosome replication
DB29_RS10055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DB29_RS10085	COG0745	RESPONSE REGULATOR receiver
DB29_RS10090	COG5002	protein histidine kinase activity
DB29_RS10100	COG4853	Protein conserved in bacteria
DB29_RS10105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DB29_RS10110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DB29_RS10115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DB29_RS10145	COG1063	alcohol dehydrogenase
DB29_RS10150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DB29_RS10155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DB29_RS10165	COG0235	Class ii aldolase
DB29_RS10170	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DB29_RS10170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DB29_RS10180	COG3716	PTS system mannose fructose sorbose family IID component
DB29_RS10200	COG1131	(ABC) transporter
DB29_RS10230	COG0601	transmembrane transport
DB29_RS10240	COG0444	Belongs to the ABC transporter superfamily
DB29_RS10245	COG4608	Belongs to the ABC transporter superfamily
DB29_RS10265	COG3275	phosphorelay sensor kinase activity
DB29_RS10275	COG1966	Carbon starvation protein
DB29_RS10300	COG1595	DNA-templated transcription, initiation
DB29_RS10315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DB29_RS10320	COG1802	Transcriptional regulator
DB29_RS10325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DB29_RS10340	COG0372	Belongs to the citrate synthase family
DB29_RS10345	COG0583	DNA-binding transcription factor activity
DB29_RS10360	COG2186	Transcriptional regulator
DB29_RS10365	COG2186	Transcriptional regulator
DB29_RS10370	COG0277	FAD linked oxidase domain protein
DB29_RS10375	COG0247	lactate metabolic process
DB29_RS10380	COG0579	oxidoreductase
DB29_RS10385	COG2508	Transcriptional regulator
DB29_RS10395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DB29_RS10400	COG0402	S-adenosylhomocysteine deaminase activity
DB29_RS10415	COG2182	Extracellular solute-binding protein
DB29_RS10420	COG1175	transmembrane transport
DB29_RS10425	COG3833	ABC-type maltose transport systems, permease component
DB29_RS10430	COG1609	Transcriptional regulator
DB29_RS10435	COG2031	fatty acid transporter
DB29_RS10440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DB29_RS10445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DB29_RS10455	COG0346	lactoylglutathione lyase activity
DB29_RS10460	COG0813	purine-nucleoside phosphorylase activity
DB29_RS10465	COG0523	cobalamin synthesis protein
DB29_RS10470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DB29_RS10475	COG1193	negative regulation of DNA recombination
DB29_RS10480	COG1307	EDD domain protein, DegV family
DB29_RS10515	COG2807	transmembrane transport
DB29_RS10525	COG0745	RESPONSE REGULATOR receiver
DB29_RS10545	COG2154	pterin-4-alpha-carbinolamine dehydratase
DB29_RS10550	COG0733	neurotransmitter:sodium symporter activity
DB29_RS10575	COG1114	Component of the transport system for branched-chain amino acids
DB29_RS10590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DB29_RS10595	COG3290	protein histidine kinase activity
DB29_RS10600	COG4565	transcriptional regulatory protein
DB29_RS10605	COG0471	metal ion transport
DB29_RS10635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DB29_RS10635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DB29_RS10675	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DB29_RS10680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DB29_RS10690	COG5504	Zn-dependent protease
DB29_RS10695	COG0789	Transcriptional regulator
DB29_RS10705	COG1597	lipid kinase activity
DB29_RS10710	COG2323	membrane
DB29_RS10715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DB29_RS10720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DB29_RS10725	COG1132	(ABC) transporter
DB29_RS10730	COG0753	catalase activity
DB29_RS10740	COG2814	Major facilitator Superfamily
DB29_RS10745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DB29_RS10750	COG0840	transmembrane signaling receptor activity
DB29_RS10760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS10765	COG0561	phosphatase activity
DB29_RS10770	COG0803	Belongs to the bacterial solute-binding protein 9 family
DB29_RS10775	COG1121	(ABC) transporter
DB29_RS10780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB29_RS10780	COG1321	iron dependent repressor
DB29_RS10785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB29_RS10800	COG2814	Major facilitator Superfamily
DB29_RS10805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DB29_RS10810	COG0551	DNA topoisomerase type I activity
DB29_RS10810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DB29_RS10815	COG1785	Belongs to the alkaline phosphatase family
DB29_RS10825	COG0024	Methionine aminopeptidase
DB29_RS10830	COG2268	Band 7 protein
DB29_RS10845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB29_RS10845	COG0723	plastoquinol--plastocyanin reductase activity
DB29_RS10850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DB29_RS10855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB29_RS10860	COG0513	Belongs to the DEAD box helicase family
DB29_RS10895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB29_RS10910	COG2986	histidine ammonia-lyase
DB29_RS10915	COG0351	phosphomethylpyrimidine kinase
DB29_RS10925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DB29_RS10935	COG0004	ammonium transporteR
DB29_RS10955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DB29_RS10960	COG0456	acetyltransferase
DB29_RS10965	COG2363	Small membrane protein
DB29_RS10975	COG3773	Cell wall hydrolase
DB29_RS10985	COG1725	Transcriptional regulator
DB29_RS10990	COG1131	(ABC) transporter
DB29_RS10995	COG4152	abc transporter atp-binding protein
DB29_RS11000	COG1668	transmembrane transport
DB29_RS11020	COG1024	Enoyl-CoA hydratase
DB29_RS11025	COG0280	phosphate acetyltransferase
DB29_RS11030	COG0095	Lipoate-protein ligase
DB29_RS11035	COG1301	dicarboxylic acid transport
DB29_RS11040	COG1078	dGTPase activity
DB29_RS11045	COG3465	dGTPase activity
DB29_RS11060	COG3764	Sortase (surface protein transpeptidase)
DB29_RS11080	COG1164	Oligoendopeptidase f
DB29_RS11090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB29_RS11095	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DB29_RS11100	COG0010	Belongs to the arginase family
DB29_RS11110	COG0018	arginyl-trna synthetase
DB29_RS11115	COG2839	Protein conserved in bacteria
DB29_RS11120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DB29_RS11125	COG2181	nitrate reductase activity
DB29_RS11125	COG0247	lactate metabolic process
DB29_RS11130	COG0183	Belongs to the thiolase family
DB29_RS11135	COG1250	3-hydroxyacyl-CoA dehydrogenase
DB29_RS11140	COG1960	acyl-CoA dehydrogenase activity
DB29_RS11150	COG3343	RNA polymerase activity
DB29_RS11155	COG0504	CTP synthase activity
DB29_RS11170	COG0191	fructose-bisphosphate aldolase activity
DB29_RS11175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DB29_RS11180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DB29_RS11185	COG1494	fructose-1,6-bisphosphatase
DB29_RS11190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DB29_RS11195	COG0254	rRNA binding
DB29_RS11200	COG1435	thymidine kinase activity
DB29_RS11210	COG0446	pyridine nucleotide-disulphide oxidoreductase
DB29_RS11215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DB29_RS11235	COG0009	L-threonylcarbamoyladenylate synthase
DB29_RS11245	COG1971	Probably functions as a manganese efflux pump
DB29_RS11260	COG0698	ribose 5-phosphate isomerase
DB29_RS11265	COG4475	Protein of unknown function (DUF436)
DB29_RS11270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DB29_RS11275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DB29_RS11280	COG0456	acetyltransferase
DB29_RS11285	COG1404	Belongs to the peptidase S8 family
DB29_RS11300	COG0356	it plays a direct role in the translocation of protons across the membrane
DB29_RS11305	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DB29_RS11310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DB29_RS11315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DB29_RS11320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DB29_RS11325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DB29_RS11330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DB29_RS11335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DB29_RS11350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DB29_RS11355	COG2385	sporulation resulting in formation of a cellular spore
DB29_RS11360	COG0739	heme binding
DB29_RS11365	COG2076	Multidrug Resistance protein
DB29_RS11370	COG2076	Multidrug Resistance protein
DB29_RS11375	COG1609	Transcriptional regulator
DB29_RS11380	COG1077	Cell shape determining protein MreB Mrl
DB29_RS11385	COG4786	Flagellar basal body rod
DB29_RS11390	COG4786	Flagellar basal body rod
DB29_RS11415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DB29_RS11425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DB29_RS11440	COG2318	DinB family
DB29_RS11450	COG1388	LysM domain
DB29_RS11450	COG0791	NLP P60 protein
DB29_RS11455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DB29_RS11465	COG2388	GCN5-related N-acetyl-transferase
DB29_RS11470	COG1316	TRANSCRIPTIONal
DB29_RS11475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DB29_RS11480	COG0772	Belongs to the SEDS family
DB29_RS11485	COG0537	adenosine 5'-monophosphoramidase activity
DB29_RS11490	COG0590	tRNA wobble adenosine to inosine editing
DB29_RS11500	COG1316	TRANSCRIPTIONal
DB29_RS11505	COG3944	biosynthesis protein
DB29_RS11510	COG0489	protein tyrosine kinase activity
DB29_RS11515	COG4464	protein tyrosine phosphatase activity
DB29_RS11635	COG2723	6-phospho-beta-galactosidase activity
DB29_RS11655	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS11660	COG2910	NAD(P)H-binding
DB29_RS11670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DB29_RS11705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DB29_RS11715	COG0395	ABC-type sugar transport system, permease component
DB29_RS11720	COG1175	transmembrane transport
DB29_RS11730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DB29_RS11735	COG1984	allophanate hydrolase subunit 2
DB29_RS11740	COG1914	H( )-stimulated, divalent metal cation uptake system
DB29_RS11745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DB29_RS11755	COG0778	Nitroreductase
DB29_RS11760	COG1609	Transcriptional regulator
DB29_RS11765	COG1621	beta-fructofuranosidase activity
DB29_RS11770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS11770	COG1263	PTS System
DB29_RS11780	COG0300	oxidoreductase activity
DB29_RS11795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DB29_RS11820	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS11825	COG0537	adenosine 5'-monophosphoramidase activity
DB29_RS11840	COG1116	anion transmembrane transporter activity
DB29_RS11845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS11860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS11870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DB29_RS11885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DB29_RS11890	COG2080	2 iron, 2 sulfur cluster binding
DB29_RS11895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DB29_RS11900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS11905	COG2508	Transcriptional regulator
DB29_RS11915	COG3648	Uricase
DB29_RS11915	COG3195	allantoin biosynthetic process
DB29_RS11925	COG1288	antiporter activity
DB29_RS11930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DB29_RS11935	COG0154	amidase activity
DB29_RS11940	COG3361	conserved protein (COG2071)
DB29_RS11995	COG0693	protein deglycase activity
DB29_RS12000	COG1116	anion transmembrane transporter activity
DB29_RS12005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS12025	COG5658	integral membrane protein
DB29_RS12030	COG0640	Transcriptional regulator
DB29_RS12035	COG0583	DNA-binding transcription factor activity
DB29_RS12040	COG4122	O-methyltransferase activity
DB29_RS12045	COG1115	amino acid carrier protein
DB29_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS12070	COG0697	spore germination
DB29_RS12075	COG0814	amino acid
DB29_RS12090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DB29_RS12095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DB29_RS12100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DB29_RS12105	COG2244	polysaccharide biosynthetic process
DB29_RS12140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DB29_RS12155	COG1091	dTDP-4-dehydrorhamnose reductase activity
DB29_RS12190	COG2249	NAD(P)H dehydrogenase (quinone) activity
DB29_RS12195	COG1733	regulation of RNA biosynthetic process
DB29_RS12255	COG1486	melibiose metabolic process
DB29_RS12270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS12270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB29_RS12275	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB29_RS12285	COG2971	BadF BadG BcrA BcrD
DB29_RS12290	COG0583	DNA-binding transcription factor activity
DB29_RS12300	COG0747	negative chemotaxis
DB29_RS12305	COG0601	transmembrane transport
DB29_RS12310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB29_RS12315	COG0444	Belongs to the ABC transporter superfamily
DB29_RS12320	COG4608	Belongs to the ABC transporter superfamily
DB29_RS12325	COG1473	amidohydrolase
DB29_RS12330	COG0471	metal ion transport
DB29_RS12340	COG1473	amidohydrolase
DB29_RS12355	COG1840	ABC-type Fe3 transport system, periplasmic component
DB29_RS12360	COG3842	ATPase activity
DB29_RS12370	COG2972	Histidine kinase
DB29_RS12375	COG2207	Transcriptional regulator
DB29_RS12375	COG4753	response regulator
DB29_RS12385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DB29_RS12390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB29_RS12395	COG2205	protein histidine kinase activity
DB29_RS12400	COG0745	RESPONSE REGULATOR receiver
DB29_RS12405	COG1131	(ABC) transporter
DB29_RS12450	COG1741	Belongs to the pirin family
DB29_RS12455	COG1733	regulation of RNA biosynthetic process
DB29_RS12460	COG0402	S-adenosylhomocysteine deaminase activity
DB29_RS12475	COG3546	catalase activity
DB29_RS12495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DB29_RS12500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DB29_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
DB29_RS12535	COG2814	Major facilitator Superfamily
DB29_RS12540	COG1063	alcohol dehydrogenase
DB29_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS12550	COG1349	DNA-binding transcription factor activity
DB29_RS12555	COG0698	ribose 5-phosphate isomerase
DB29_RS12560	COG2376	Dihydroxyacetone kinase
DB29_RS12565	COG2376	Dihydroxyacetone kinase
DB29_RS12570	COG1494	fructose-1,6-bisphosphatase
DB29_RS12575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB29_RS12595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB29_RS12600	COG1609	Transcriptional regulator
DB29_RS12605	COG4682	membrane
DB29_RS12655	COG1794	racemase activity, acting on amino acids and derivatives
DB29_RS12670	COG2207	Transcriptional regulator
DB29_RS12670	COG4753	response regulator
DB29_RS12675	COG2972	Histidine kinase
DB29_RS12680	COG1653	transport
DB29_RS12685	COG1175	transmembrane transport
DB29_RS12690	COG0395	ABC-type sugar transport system, permease component
DB29_RS12695	COG0445	tRNA wobble uridine modification
DB29_RS12705	COG1263	PTS System
DB29_RS12705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS12710	COG1737	Transcriptional regulator
DB29_RS12740	COG1349	DNA-binding transcription factor activity
DB29_RS12750	COG3414	Phosphotransferase system galactitol-specific IIB component
DB29_RS12755	COG3775	system Galactitol-specific IIC component
DB29_RS12760	COG1063	alcohol dehydrogenase
DB29_RS12780	COG3655	Transcriptional regulator
DB29_RS12785	COG3739	integral membrane protein
DB29_RS12795	COG3848	Pyruvate phosphate dikinase
DB29_RS12795	COG0574	Belongs to the PEP-utilizing enzyme family
DB29_RS12805	COG0583	DNA-binding transcription factor activity
DB29_RS12810	COG0730	response to heat
DB29_RS12815	COG2972	Histidine kinase
DB29_RS12820	COG2207	Transcriptional regulator
DB29_RS12820	COG4753	response regulator
DB29_RS12835	COG1175	transmembrane transport
DB29_RS12840	COG0395	ABC-type sugar transport system, permease component
DB29_RS12845	COG3408	Glycogen debranching enzyme
DB29_RS12850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DB29_RS12860	COG4948	Mandelate Racemase Muconate Lactonizing
DB29_RS12865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS12865	COG1263	PTS System
DB29_RS12865	COG2190	(PTS) system
DB29_RS12880	COG2972	Histidine kinase
DB29_RS12880	COG0745	RESPONSE REGULATOR receiver
DB29_RS12885	COG3279	Response regulator of the LytR AlgR family
DB29_RS12900	COG1396	sequence-specific DNA binding
DB29_RS12915	COG1132	(ABC) transporter
DB29_RS12940	COG1131	(ABC) transporter
DB29_RS12955	COG0745	RESPONSE REGULATOR receiver
DB29_RS12960	COG3850	Histidine kinase
DB29_RS12960	COG5002	protein histidine kinase activity
DB29_RS12985	COG0483	inositol monophosphate 1-phosphatase activity
DB29_RS13005	COG1609	Transcriptional regulator
DB29_RS13010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DB29_RS13015	COG1869	D-ribose catabolic process
DB29_RS13020	COG1129	ABC transporter
DB29_RS13025	COG1172	Belongs to the binding-protein-dependent transport system permease family
DB29_RS13030	COG1879	ABC-type sugar transport system periplasmic component
DB29_RS13045	COG0300	oxidoreductase activity
DB29_RS13075	COG1376	ErfK ybiS ycfS ynhG family protein
DB29_RS13080	COG2312	Erythromycin esterase
DB29_RS13090	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS13105	COG2207	Transcriptional regulator
DB29_RS13110	COG1131	(ABC) transporter
DB29_RS13120	COG1378	Sugar-specific transcriptional regulator TrmB
DB29_RS13125	COG0697	spore germination
DB29_RS13150	COG1609	Transcriptional regulator
DB29_RS13155	COG2182	Extracellular solute-binding protein
DB29_RS13160	COG1175	transmembrane transport
DB29_RS13165	COG3833	ABC-type maltose transport systems, permease component
DB29_RS13175	COG1874	Beta-galactosidase
DB29_RS13190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS13195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DB29_RS13200	COG0789	Transcriptional regulator
DB29_RS13220	COG0693	protein deglycase activity
DB29_RS13245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS13260	COG0395	ABC-type sugar transport system, permease component
DB29_RS13265	COG1175	transmembrane transport
DB29_RS13270	COG1653	transport
DB29_RS13275	COG1136	(ABC) transporter
DB29_RS13280	COG0577	efflux transmembrane transporter activity
DB29_RS13290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DB29_RS13295	COG0697	spore germination
DB29_RS13315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB29_RS13315	COG2207	Transcriptional regulator
DB29_RS13320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB29_RS13325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS13330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS13335	COG2819	hydrolase of the alpha beta superfamily
DB29_RS13350	COG2602	Beta-lactamase
DB29_RS13360	COG0840	transmembrane signaling receptor activity
DB29_RS13365	COG1609	Transcriptional regulator
DB29_RS13375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB29_RS13380	COG2207	Transcriptional regulator
DB29_RS13390	COG1609	Transcriptional regulator
DB29_RS13395	COG0673	inositol 2-dehydrogenase activity
DB29_RS13410	COG0395	ABC-type sugar transport system, permease component
DB29_RS13415	COG1082	Xylose isomerase domain protein TIM barrel
DB29_RS13430	COG2197	response regulator
DB29_RS13450	COG1366	Belongs to the anti-sigma-factor antagonist family
DB29_RS13475	COG2720	vancomycin resistance protein
DB29_RS13490	COG2135	peptidase activity
DB29_RS13520	COG0542	response to heat
DB29_RS13525	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB29_RS13550	COG2311	Membrane
DB29_RS13555	COG1940	carbohydrate kinase activity
DB29_RS13565	COG1175	transmembrane transport
DB29_RS13570	COG0395	ABC-type sugar transport system, permease component
DB29_RS13575	COG0673	inositol 2-dehydrogenase activity
DB29_RS13580	COG0673	inositol 2-dehydrogenase activity
DB29_RS13590	COG0596	Alpha beta hydrolase
DB29_RS13600	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS13610	COG0477	Major facilitator Superfamily
DB29_RS13615	COG1309	transcriptional regulator
DB29_RS13620	COG2226	methyltransferase
DB29_RS13625	COG1063	alcohol dehydrogenase
DB29_RS13640	COG2329	Antibiotic biosynthesis monooxygenase
DB29_RS13645	COG5386	Cell surface protein
DB29_RS13650	COG5386	Cell surface protein
DB29_RS13665	COG1120	ATPase activity
DB29_RS13670	COG4509	Sortase family
DB29_RS13675	COG1253	flavin adenine dinucleotide binding
DB29_RS13680	COG2113	Glycine betaine
DB29_RS13690	COG3546	catalase activity
DB29_RS13695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DB29_RS13700	COG1063	alcohol dehydrogenase
DB29_RS13705	COG1587	Uroporphyrinogen-III synthase
DB29_RS13720	COG1131	(ABC) transporter
DB29_RS13735	COG1309	transcriptional regulator
DB29_RS13740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DB29_RS13755	COG2323	membrane
DB29_RS13765	COG0583	DNA-binding transcription factor activity
DB29_RS13770	COG0431	NADPH-dependent FMN reductase
DB29_RS13775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS13785	COG1116	anion transmembrane transporter activity
DB29_RS13790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS13795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DB29_RS13800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS13805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DB29_RS13810	COG0583	DNA-binding transcription factor activity
DB29_RS13815	COG0640	Transcriptional regulator
DB29_RS13825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DB29_RS13830	COG2032	superoxide dismutase activity
DB29_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS13850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DB29_RS13855	COG1609	Transcriptional regulator
DB29_RS13890	COG4585	Histidine kinase
DB29_RS13895	COG2197	response regulator
DB29_RS13900	COG4149	molybdate abc transporter
DB29_RS13905	COG0725	ABC transporter, periplasmic molybdate-binding protein
DB29_RS13910	COG3534	alpha-L-arabinofuranosidase
DB29_RS13920	COG3507	Belongs to the glycosyl hydrolase 43 family
DB29_RS13925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DB29_RS13935	COG1682	transport, permease protein
DB29_RS13940	COG1134	teichoic acid transport
DB29_RS13945	COG1694	Mazg nucleotide pyrophosphohydrolase
DB29_RS13975	COG1609	Transcriptional regulator
DB29_RS13990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DB29_RS13995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DB29_RS14000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DB29_RS14010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DB29_RS14020	COG2217	Heavy metal translocating P-type atpase
DB29_RS14035	COG3414	Phosphotransferase system galactitol-specific IIB component
DB29_RS14040	COG3775	system Galactitol-specific IIC component
DB29_RS14045	COG1063	alcohol dehydrogenase
DB29_RS14050	COG1063	alcohol dehydrogenase
DB29_RS14055	COG0488	(ABC) transporter
DB29_RS14065	COG1388	LysM domain
DB29_RS14070	COG1619	proteins homologs of microcin C7 resistance protein MccF
DB29_RS14075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS14075	COG1263	PTS System
DB29_RS14080	COG3711	transcriptional antiterminator
DB29_RS14090	COG2197	response regulator
DB29_RS14095	COG4585	Histidine kinase
DB29_RS14110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DB29_RS14115	COG1228	amidohydrolase
DB29_RS14120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS14125	COG0402	S-adenosylhomocysteine deaminase activity
DB29_RS14150	COG0457	Tetratricopeptide repeat
DB29_RS14155	COG1078	dGTPase activity
DB29_RS14205	COG1418	mRNA catabolic process
DB29_RS14210	COG0124	histidyl-tRNA synthetase
DB29_RS14220	COG2261	transglycosylase associated protein
DB29_RS14230	COG0456	acetyltransferase
DB29_RS14250	COG1653	transport
DB29_RS14260	COG0395	ABC-type sugar transport system, permease component
DB29_RS14270	COG0501	Belongs to the peptidase M48B family
DB29_RS14275	COG5504	Zn-dependent protease
DB29_RS14280	COG2247	cell wall binding repeat
DB29_RS14280	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB29_RS14290	COG1368	sulfuric ester hydrolase activity
DB29_RS14305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DB29_RS14310	COG0384	phenazine biosynthesis protein PhzF
DB29_RS14320	COG0673	inositol 2-dehydrogenase activity
DB29_RS14325	COG1917	Cupin 2, conserved barrel domain protein
DB29_RS14325	COG2207	Transcriptional regulator
DB29_RS14335	COG0673	inositol 2-dehydrogenase activity
DB29_RS14340	COG1653	transport
DB29_RS14345	COG1175	transmembrane transport
DB29_RS14350	COG0395	ABC-type sugar transport system, permease component
DB29_RS14360	COG2207	Transcriptional regulator
DB29_RS14360	COG3708	Transcriptional regulator
DB29_RS14370	COG0673	inositol 2-dehydrogenase activity
DB29_RS14380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DB29_RS14390	COG0395	ABC-type sugar transport system, permease component
DB29_RS14420	COG3420	alginic acid biosynthetic process
DB29_RS14430	COG1309	transcriptional regulator
DB29_RS14445	COG1609	Transcriptional regulator
DB29_RS14455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DB29_RS14465	COG1482	cell wall glycoprotein biosynthetic process
DB29_RS14475	COG1968	undecaprenyl-diphosphatase activity
DB29_RS14480	COG2270	Major facilitator Superfamily
DB29_RS14485	COG3835	regulator
DB29_RS14490	COG0277	FAD linked oxidase domain protein
DB29_RS14495	COG0247	lactate metabolic process
DB29_RS14500	COG1116	anion transmembrane transporter activity
DB29_RS14515	COG0456	acetyltransferase
DB29_RS14520	COG1846	Transcriptional regulator
DB29_RS14535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS14550	COG3730	PTS system glucitol sorbitol-specific
DB29_RS14555	COG3732	PTS system glucitol sorbitol-specific
DB29_RS14575	COG2217	Heavy metal translocating P-type atpase
DB29_RS14580	COG0577	efflux transmembrane transporter activity
DB29_RS14585	COG1136	(ABC) transporter
DB29_RS14590	COG5002	protein histidine kinase activity
DB29_RS14595	COG0745	RESPONSE REGULATOR receiver
DB29_RS14605	COG1940	carbohydrate kinase activity
DB29_RS14610	COG4187	Peptidase family M20/M25/M40
DB29_RS14615	COG2814	Major facilitator Superfamily
DB29_RS14620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DB29_RS14625	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DB29_RS14630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DB29_RS14640	COG1368	sulfuric ester hydrolase activity
DB29_RS14645	COG0516	GMP reductase activity
DB29_RS14660	COG0395	ABC-type sugar transport system, permease component
DB29_RS14680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DB29_RS14685	COG3842	ATPase activity
DB29_RS14725	COG0589	response to stress
DB29_RS14735	COG1105	Belongs to the carbohydrate kinase PfkB family
DB29_RS14740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS14740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS14740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS14745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS14745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS14745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB29_RS14760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DB29_RS14775	COG0583	DNA-binding transcription factor activity
DB29_RS14780	COG0655	NAD(P)H dehydrogenase (quinone) activity
DB29_RS14790	COG1309	transcriptional regulator
DB29_RS14795	COG0842	Transport permease protein
DB29_RS14800	COG1131	(ABC) transporter
DB29_RS14825	COG1473	amidohydrolase
DB29_RS14830	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DB29_RS14870	COG0438	transferase activity, transferring glycosyl groups
DB29_RS14885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DB29_RS14895	COG1215	transferase activity, transferring glycosyl groups
DB29_RS14900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DB29_RS15000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DB29_RS15005	COG2169	Transcriptional regulator
DB29_RS15010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DB29_RS15015	COG0673	inositol 2-dehydrogenase activity
DB29_RS15020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DB29_RS15025	COG0561	phosphatase activity
DB29_RS15030	COG2318	DinB family
DB29_RS15035	COG2378	regulation of single-species biofilm formation
DB29_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS15050	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DB29_RS15060	COG2197	response regulator
DB29_RS15065	COG4585	Histidine kinase
DB29_RS15065	COG2203	Gaf domain
DB29_RS15075	COG2112	serine threonine protein kinase
DB29_RS15080	COG1959	2 iron, 2 sulfur cluster binding
DB29_RS15090	COG0800	Aldolase
DB29_RS15105	COG1131	(ABC) transporter
DB29_RS15110	COG1725	Transcriptional regulator
DB29_RS15130	COG1396	sequence-specific DNA binding
DB29_RS15140	COG1472	Belongs to the glycosyl hydrolase 3 family
DB29_RS15150	COG1175	transmembrane transport
DB29_RS15155	COG0395	ABC-type sugar transport system, permease component
DB29_RS15160	COG3842	ATPase activity
DB29_RS15170	COG1609	Transcriptional regulator
DB29_RS15175	COG4209	transmembrane transport
DB29_RS15180	COG0395	ABC-type sugar transport system, permease component
DB29_RS15190	COG1621	beta-fructofuranosidase activity
DB29_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS15205	COG3858	chitin binding
DB29_RS15205	COG1388	LysM domain
DB29_RS15215	COG1335	isochorismatase
DB29_RS15220	COG4112	unkown
DB29_RS15225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB29_RS15230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB29_RS15235	COG1780	Probably involved in ribonucleotide reductase function
DB29_RS15245	COG1215	transferase activity, transferring glycosyl groups
DB29_RS15250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DB29_RS15255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DB29_RS15265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DB29_RS15270	COG0463	Glycosyl transferase, family 2
DB29_RS15270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DB29_RS15275	COG1215	transferase activity, transferring glycosyl groups
DB29_RS15275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DB29_RS15280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DB29_RS15285	COG4193	domain, Protein
DB29_RS15290	COG1316	TRANSCRIPTIONal
DB29_RS15305	COG4608	Belongs to the ABC transporter superfamily
DB29_RS15310	COG0601	transmembrane transport
DB29_RS15320	COG4166	transmembrane transport
DB29_RS15325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DB29_RS15330	COG1739	Uncharacterized protein family UPF0029
DB29_RS15345	COG1307	EDD domain protein, DegV family
DB29_RS15350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DB29_RS15365	COG2747	anti-sigma28 factor FlgM
DB29_RS15375	COG4786	Flagellar basal body rod
DB29_RS15375	COG1256	bacterial-type flagellum assembly
DB29_RS15380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DB29_RS15385	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DB29_RS15390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DB29_RS15395	COG1334	flagellar protein FlaG
DB29_RS15400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DB29_RS15405	COG1516	flagellar protein fliS
DB29_RS15420	COG1278	Cold shock
DB29_RS15425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DB29_RS15430	COG0653	protein targeting
DB29_RS15440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB29_RS15445	COG2884	Cell division ATP-binding protein ftsE
DB29_RS15450	COG2177	Part of the ABC transporter FtsEX involved in
DB29_RS15455	COG0739	heme binding
DB29_RS15460	COG0793	Belongs to the peptidase S41A family
DB29_RS15460	COG3409	Peptidoglycan-binding domain 1 protein
DB29_RS15475	COG0556	nucleotide-excision repair
DB29_RS15480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DB29_RS15485	COG3595	metallopeptidase activity
DB29_RS15495	COG1950	PFAM Membrane protein of
DB29_RS15500	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DB29_RS15505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DB29_RS15510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DB29_RS15515	COG0546	phosphoglycolate phosphatase activity
DB29_RS15520	COG0110	maltose O-acetyltransferase activity
DB29_RS15525	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DB29_RS15530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DB29_RS15535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DB29_RS15540	COG0131	Imidazoleglycerol-phosphate dehydratase
DB29_RS15545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DB29_RS15550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DB29_RS15555	COG0107	imidazoleglycerol-phosphate synthase activity
DB29_RS15560	COG0140	phosphoribosyl-ATP diphosphatase activity
DB29_RS15560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DB29_RS15570	COG2124	cytochrome p450
DB29_RS15580	COG0492	ferredoxin-NADP+ reductase activity
DB29_RS15585	COG1051	belongs to the nudix hydrolase family
DB29_RS15590	COG1660	Displays ATPase and GTPase activities
DB29_RS15595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DB29_RS15600	COG1481	regulation of sporulation
DB29_RS15605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS15610	COG1174	glycine betaine transport
DB29_RS15615	COG1732	Glycine betaine
DB29_RS15620	COG1174	glycine betaine transport
DB29_RS15625	COG0517	IMP dehydrogenase activity
DB29_RS15625	COG1125	glycine betaine transport
DB29_RS15635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB29_RS15640	COG0740	serine-type endopeptidase activity
DB29_RS15645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DB29_RS15675	COG0126	phosphoglycerate kinase activity
DB29_RS15680	COG0149	triose-phosphate isomerase activity
DB29_RS15685	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DB29_RS15690	COG0148	phosphopyruvate hydratase activity
DB29_RS15695	COG1802	Transcriptional regulator
DB29_RS15700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB29_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
DB29_RS15710	COG4948	Mandelate Racemase Muconate Lactonizing
DB29_RS15735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DB29_RS15740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB29_RS15750	COG1647	Serine aminopeptidase, S33
DB29_RS15755	COG0557	exoribonuclease II activity
DB29_RS15760	COG2259	Doxx family
DB29_RS15765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DB29_RS15785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DB29_RS15800	COG4533	DNA binding
DB29_RS15810	COG1250	3-hydroxyacyl-CoA dehydrogenase
DB29_RS15810	COG1024	Enoyl-CoA hydratase
DB29_RS15815	COG0183	Belongs to the thiolase family
DB29_RS15820	COG1960	acyl-CoA dehydrogenase activity
DB29_RS15825	COG1393	Belongs to the ArsC family
DB29_RS15830	COG0509	glycine decarboxylation via glycine cleavage system
DB29_RS15835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DB29_RS15840	COG2011	ABC-type metal ion transport system permease component
DB29_RS15845	COG1464	Belongs to the NlpA lipoprotein family
DB29_RS15855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB29_RS15860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DB29_RS15865	COG0396	ATPase activity
DB29_RS15870	COG0719	Fe-S assembly protein
DB29_RS15875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DB29_RS15880	COG0822	iron-sulfur transferase activity
DB29_RS15885	COG0719	Fe-S assembly protein
DB29_RS15890	COG2224	Isocitrate lyase
DB29_RS15895	COG3711	transcriptional antiterminator
DB29_RS15900	COG2723	6-phospho-beta-galactosidase activity
DB29_RS15905	COG2226	methyltransferase
DB29_RS15910	COG0667	Aldo Keto reductase
DB29_RS15915	COG2207	Transcriptional regulator
DB29_RS15915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB29_RS15960	COG1801	Protein of unknown function DUF72
DB29_RS15965	COG0730	response to heat
DB29_RS15970	COG0737	Belongs to the 5'-nucleotidase family
DB29_RS15975	COG3377	Domain of unknown function (DUF1805)
DB29_RS15980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DB29_RS15995	COG1757	Na H antiporter
DB29_RS16000	COG0739	heme binding
DB29_RS16005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DB29_RS16015	COG4470	Protein conserved in bacteria
DB29_RS16025	COG2445	Protein of unknown function DUF86
DB29_RS16030	COG0647	UMP catabolic process
DB29_RS16035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DB29_RS16040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DB29_RS16045	COG0460	homoserine dehydrogenase
DB29_RS16050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DB29_RS16055	COG0083	homoserine kinase activity
DB29_RS16060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DB29_RS16065	COG4837	Protein of unknown function (DUF1462)
DB29_RS16070	COG1252	NADH dehydrogenase
DB29_RS16075	COG4844	belongs to the
DB29_RS16085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DB29_RS16090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DB29_RS16100	COG0316	Belongs to the HesB IscA family
DB29_RS16105	COG0765	amino acid transport
DB29_RS16110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB29_RS16120	COG3711	transcriptional antiterminator
DB29_RS16125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS16130	COG0246	Mannitol dehydrogenase
DB29_RS16135	COG0492	ferredoxin-NADP+ reductase activity
DB29_RS16140	COG1252	NADH dehydrogenase
DB29_RS16150	COG3584	3D domain protein
DB29_RS16155	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DB29_RS16160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DB29_RS16175	COG2056	Na+-H+ antiporter family
DB29_RS16180	COG0776	regulation of translation
DB29_RS16185	COG1295	ribonuclease BN
DB29_RS16190	COG1854	S-ribosylhomocysteine lyase activity
DB29_RS16195	COG1522	sequence-specific DNA binding
DB29_RS16200	COG0436	Aminotransferase
DB29_RS16205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DB29_RS16215	COG1098	S1 RNA binding domain
DB29_RS16220	COG2155	Conserved Protein
DB29_RS16225	COG1979	alcohol dehydrogenase
DB29_RS16230	COG1181	Belongs to the D-alanine--D-alanine ligase family
DB29_RS16235	COG0166	Belongs to the GPI family
DB29_RS16255	COG1227	inorganic diphosphatase activity
DB29_RS16260	COG0109	protoheme IX farnesyltransferase activity
DB29_RS16265	COG4846	Membrane protein involved in cytochrome C biogenesis
DB29_RS16285	COG1823	symporter activity
DB29_RS16290	COG0671	phosphoesterase, PA-phosphatase related
DB29_RS16295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB29_RS16300	COG4605	iron ion homeostasis
DB29_RS16305	COG4604	ABC transporter, ATP-binding protein
DB29_RS16325	COG1428	Deoxynucleoside kinase
DB29_RS16330	COG1428	Deoxynucleoside kinase
DB29_RS16335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DB29_RS16345	COG2814	Major facilitator Superfamily
DB29_RS16350	COG0494	nUDIX hydrolase
DB29_RS16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DB29_RS16360	COG1116	anion transmembrane transporter activity
DB29_RS16365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DB29_RS16370	COG1506	peptidase
DB29_RS16375	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DB29_RS16380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DB29_RS16385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DB29_RS16390	COG2267	carboxylic ester hydrolase activity
DB29_RS16395	COG0288	reversible hydration of carbon dioxide
DB29_RS16400	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DB29_RS16405	COG2814	Major facilitator Superfamily
DB29_RS16410	COG0039	L-malate dehydrogenase activity
DB29_RS16415	COG0495	leucyl-tRNA aminoacylation
DB29_RS16440	COG2081	HI0933 family
DB29_RS16445	COG1473	amidohydrolase
DB29_RS16450	COG0432	Pfam Uncharacterised protein family UPF0047
DB29_RS16455	COG3386	PFAM SMP-30 Gluconolaconase
DB29_RS16460	COG2244	polysaccharide biosynthetic process
DB29_RS16465	COG0772	Belongs to the SEDS family
DB29_RS16470	COG0772	Belongs to the SEDS family
DB29_RS16475	COG1187	pseudouridine synthase activity
DB29_RS16480	COG1349	DNA-binding transcription factor activity
DB29_RS16485	COG0346	lactoylglutathione lyase activity
DB29_RS16490	COG0300	oxidoreductase activity
DB29_RS16495	COG0789	Transcriptional regulator
DB29_RS16500	COG3708	Transcriptional regulator
DB29_RS16500	COG2207	Transcriptional regulator
DB29_RS16505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DB29_RS16515	COG1380	Effector of murein hydrolase LrgA
DB29_RS16520	COG1346	cytolysis
DB29_RS16535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DB29_RS16540	COG0022	dehydrogenase e1 component
DB29_RS16545	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB29_RS16560	COG0788	formyltetrahydrofolate deformylase activity
DB29_RS16565	COG0510	thiamine kinase activity
DB29_RS16575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DB29_RS16585	COG1363	Peptidase, m42
DB29_RS16590	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DB29_RS16605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB29_RS16610	COG4848	Belongs to the UPF0354 family
DB29_RS16615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DB29_RS16620	COG1674	ftsk spoiiie
DB29_RS16625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DB29_RS16630	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DB29_RS16635	COG4980	gas vesicle protein
DB29_RS16640	COG1605	Chorismate mutase
DB29_RS16640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DB29_RS16650	COG0123	including yeast histone deacetylase and acetoin utilization protein
DB29_RS16655	COG0517	IMP dehydrogenase activity
DB29_RS16660	COG0454	-acetyltransferase
DB29_RS16665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DB29_RS16670	COG4499	WXG100 protein secretion system (Wss), protein YukC
DB29_RS16670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB29_RS16675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DB29_RS16680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DB29_RS16685	COG1956	GAF domain-containing protein
DB29_RS16695	COG1309	transcriptional regulator
DB29_RS16700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DB29_RS16705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DB29_RS16710	COG1104	cysteine desulfurase activity
DB29_RS16715	COG0301	tRNA thio-modification
DB29_RS16725	COG0616	signal peptide processing
DB29_RS16730	COG1714	RDD family
DB29_RS16740	COG3874	Sporulation protein YtfJ
DB29_RS16745	COG2814	Major facilitator Superfamily
DB29_RS16750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DB29_RS16755	COG0827	DNA restriction-modification system
DB29_RS16760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DB29_RS16765	COG3481	metal-dependent phosphohydrolase, HD sub domain
DB29_RS16775	COG0137	argininosuccinate synthase activity
DB29_RS16780	COG0165	Argininosuccinate lyase
DB29_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS16795	COG0006	proline dipeptidase activity
DB29_RS16800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DB29_RS16810	COG4109	DRTGG domain
DB29_RS16820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DB29_RS16835	COG0587	DNA-directed DNA polymerase activity
DB29_RS16840	COG0281	malic enzyme
DB29_RS16845	COG2186	Transcriptional regulator
DB29_RS16850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DB29_RS16855	COG0825	malonyl-CoA metabolic process
DB29_RS16860	COG0205	6-phosphofructokinase activity
DB29_RS16870	COG3030	protein affecting phage T7 exclusion by the F plasmid
DB29_RS16875	COG2707	UPF0756 membrane protein
DB29_RS16880	COG0372	Belongs to the citrate synthase family
DB29_RS16885	COG0538	isocitrate dehydrogenase activity
DB29_RS16890	COG0039	L-malate dehydrogenase activity
DB29_RS16895	COG1522	sequence-specific DNA binding
DB29_RS16900	COG0745	RESPONSE REGULATOR receiver
DB29_RS16905	COG5002	protein histidine kinase activity
DB29_RS16910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB29_RS16910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB29_RS16915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DB29_RS16920	COG1971	Probably functions as a manganese efflux pump
DB29_RS16925	COG0237	dephospho-CoA kinase activity
DB29_RS16930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DB29_RS16935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DB29_RS16945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DB29_RS16950	COG3611	Membrane attachment protein
DB29_RS16955	COG1484	DNA-dependent DNA replication
DB29_RS16960	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DB29_RS16970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DB29_RS16985	COG2027	D-alanyl-D-alanine carboxypeptidase
DB29_RS17000	COG1136	(ABC) transporter
DB29_RS17005	COG0577	efflux transmembrane transporter activity
DB29_RS17010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DB29_RS17015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DB29_RS17020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DB29_RS17025	COG3162	membrane
DB29_RS17030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DB29_RS17040	COG1363	Peptidase, m42
DB29_RS17060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DB29_RS17065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DB29_RS17070	COG0072	phenylalanine-tRNA ligase activity
DB29_RS17075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DB29_RS17080	COG1286	toxin biosynthetic process
DB29_RS17085	COG1796	DNA polymerase
DB29_RS17085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DB29_RS17090	COG1193	negative regulation of DNA recombination
DB29_RS17095	COG3766	membrane
DB29_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
DB29_RS17105	COG1309	transcriptional regulator
DB29_RS17110	COG1024	Enoyl-CoA hydratase
DB29_RS17115	COG2086	electron transfer activity
DB29_RS17120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DB29_RS17125	COG3118	belongs to the thioredoxin family
DB29_RS17130	COG0322	excinuclease ABC activity
DB29_RS17140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DB29_RS17145	COG2009	succinate dehydrogenase
DB29_RS17150	COG1053	succinate dehydrogenase
DB29_RS17155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DB29_RS17160	COG0824	Thioesterase
DB29_RS17165	COG2197	response regulator
DB29_RS17170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB29_RS17175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DB29_RS17180	COG1846	Transcriptional regulator
DB29_RS17185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DB29_RS17200	COG5401	PFAM Sporulation and spore germination
DB29_RS17205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DB29_RS17210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DB29_RS17215	COG0622	Phosphoesterase
DB29_RS17230	COG2132	Multicopper oxidase
DB29_RS17245	COG0129	dihydroxy-acid dehydratase activity
DB29_RS17250	COG0028	Belongs to the TPP enzyme family
DB29_RS17255	COG0440	acetolactate synthase activity
DB29_RS17260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DB29_RS17265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DB29_RS17270	COG0473	3-isopropylmalate dehydrogenase activity
DB29_RS17275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DB29_RS17280	COG0066	3-isopropylmalate dehydratase activity
DB29_RS17285	COG0457	Tetratricopeptide repeat
DB29_RS17285	COG1477	protein flavinylation
DB29_RS17290	COG0544	peptidyl-prolyl cis-trans isomerase activity
DB29_RS17295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DB29_RS17300	COG0470	DNA polymerase III
DB29_RS17300	COG1067	ATP-dependent peptidase activity
DB29_RS17305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DB29_RS17310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DB29_RS17315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DB29_RS17320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DB29_RS17325	COG0181	hydroxymethylbilane synthase activity
DB29_RS17335	COG0113	porphobilinogen synthase activity
DB29_RS17340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DB29_RS17345	COG1388	LysM domain
DB29_RS17345	COG1388	LysM domain
DB29_RS17370	COG0525	valine-tRNA ligase activity
DB29_RS17375	COG0285	dihydrofolate synthase activity
DB29_RS17380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DB29_RS17390	COG4946	Tricorn protease homolog
DB29_RS17390	COG1506	peptidase
DB29_RS17390	COG0823	Involved in the tonB-independent uptake of proteins
DB29_RS17395	COG0424	maF-like protein
DB29_RS17400	COG2003	Belongs to the UPF0758 family
DB29_RS17405	COG1077	Cell shape determining protein MreB Mrl
DB29_RS17415	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DB29_RS17420	COG0850	regulation of cytokinetic process
DB29_RS17425	COG2894	cell division
DB29_RS17430	COG0693	protein deglycase activity
DB29_RS17435	COG0315	cyclic pyranopterin monophosphate synthase activity
DB29_RS17440	COG1268	BioY protein
DB29_RS17445	COG0667	Aldo Keto reductase
DB29_RS17450	COG0739	heme binding
DB29_RS17455	COG1994	Peptidase M50
DB29_RS17460	COG1530	ribonuclease E activity
DB29_RS17465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DB29_RS17470	COG2868	ribosomal protein
DB29_RS17475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DB29_RS17480	COG2002	toxin-antitoxin pair type II binding
DB29_RS17485	COG1228	amidohydrolase
DB29_RS17490	COG1573	uracil-dna glycosylase
DB29_RS17495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB29_RS17500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DB29_RS17510	COG2318	DinB family
DB29_RS17515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DB29_RS17520	COG0573	inorganic phosphate transmembrane transporter activity
DB29_RS17525	COG0581	inorganic phosphate transmembrane transporter activity
DB29_RS17530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DB29_RS17535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DB29_RS17560	COG2198	Histidine kinase
DB29_RS17560	COG0643	Histidine kinase
DB29_RS17565	COG0835	chemotaxis
DB29_RS17570	COG0367	asparagine synthase
DB29_RS17590	COG3209	COG3209 Rhs family protein
DB29_RS17605	COG1834	amidinotransferase
DB29_RS17610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DB29_RS17620	COG0425	Belongs to the sulfur carrier protein TusA family
DB29_RS17620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DB29_RS17630	COG1073	alpha beta
DB29_RS17635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB29_RS17645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DB29_RS17670	COG0561	phosphatase activity
DB29_RS17675	COG3336	cytochrome c oxidase
DB29_RS17680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DB29_RS17685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DB29_RS17690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DB29_RS17695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DB29_RS17700	COG0505	Belongs to the CarA family
DB29_RS17705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DB29_RS17710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DB29_RS17715	COG2267	carboxylic ester hydrolase activity
DB29_RS17725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DB29_RS17740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DB29_RS17745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DB29_RS17755	COG0617	tRNA 3'-terminal CCA addition
DB29_RS17765	COG3409	Peptidoglycan-binding domain 1 protein
DB29_RS17765	COG3773	Cell wall hydrolase
DB29_RS17770	COG2340	Cysteine-rich secretory protein family
DB29_RS17775	COG1072	(Pantothenic acid kinase))
DB29_RS17780	COG2357	RelA SpoT domain protein
DB29_RS17785	COG5504	Zn-dependent protease
DB29_RS17795	COG0180	Tryptophanyl-tRNA synthetase
DB29_RS17805	COG1418	mRNA catabolic process
DB29_RS17810	COG1272	protein, Hemolysin III
DB29_RS17825	COG0456	acetyltransferase
DB29_RS17830	COG1393	Belongs to the ArsC family
DB29_RS17855	COG2346	COG2346, Truncated hemoglobins
DB29_RS17860	COG0741	lytic transglycosylase activity
DB29_RS17865	COG4116	CYTH
DB29_RS17875	COG2357	RelA SpoT domain protein
DB29_RS17880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DB29_RS17885	COG0564	pseudouridine synthase activity
DB29_RS17900	COG2226	methyltransferase
DB29_RS17930	COG0210	DNA helicase
DB29_RS17935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DB29_RS17990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DB29_RS17995	COG4537	Required for transformation and DNA binding
DB29_RS18030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DB29_RS18045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DB29_RS18050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DB29_RS18055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DB29_RS18060	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DB29_RS18065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DB29_RS18070	COG0095	Lipoate-protein ligase
DB29_RS18075	COG3973	AAA domain
DB29_RS18085	COG1533	DNA photolyase activity
DB29_RS18090	COG1321	iron dependent repressor
DB29_RS18095	COG1752	Esterase of the alpha-beta hydrolase superfamily
DB29_RS18110	COG0006	proline dipeptidase activity
DB29_RS18115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DB29_RS18120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DB29_RS18135	COG3854	ATPases associated with a variety of cellular activities
DB29_RS18180	COG0511	ligase activity, forming carbon-carbon bonds
DB29_RS18185	COG0439	Biotin carboxylase
DB29_RS18190	COG1302	Protein conserved in bacteria
DB29_RS18195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DB29_RS18200	COG1570	exodeoxyribonuclease VII activity
DB29_RS18205	COG1722	exodeoxyribonuclease VII activity
DB29_RS18210	COG0142	geranyltranstransferase activity
DB29_RS18215	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DB29_RS18220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DB29_RS18225	COG1438	arginine binding
DB29_RS18230	COG0497	DNA recombination
DB29_RS18235	COG0750	zinc metalloprotease
DB29_RS18240	COG0745	RESPONSE REGULATOR receiver
DB29_RS18260	COG3290	protein histidine kinase activity
DB29_RS18260	COG3829	transcription factor binding
DB29_RS18270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DB29_RS18275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DB29_RS18280	COG0022	dehydrogenase e1 component
DB29_RS18285	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB29_RS18305	COG0561	phosphatase activity
DB29_RS18315	COG1937	Protein conserved in bacteria
DB29_RS18320	COG2608	mercury ion transmembrane transporter activity
DB29_RS18335	COG1902	pentaerythritol trinitrate reductase activity
DB29_RS18345	COG0702	epimerase
DB29_RS18365	COG0668	transmembrane transport
DB29_RS18380	COG2171	N-acyltransferase activity
DB29_RS18385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DB29_RS18390	COG1473	amidohydrolase
DB29_RS18400	COG0668	transmembrane transport
DB29_RS18405	COG0450	alkyl hydroperoxide reductase
DB29_RS18410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB29_RS18415	COG0569	domain protein
DB29_RS18420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DB29_RS18430	COG0242	peptide deformylase activity
DB29_RS18450	COG0022	dehydrogenase e1 component
DB29_RS18455	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB29_RS18465	COG0444	Belongs to the ABC transporter superfamily
DB29_RS18470	COG4608	Belongs to the ABC transporter superfamily
DB29_RS18480	COG0601	transmembrane transport
DB29_RS18485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB29_RS18495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DB29_RS18510	COG1982	Orn Lys Arg decarboxylase major
DB29_RS18520	COG4493	Belongs to the UPF0637 family
DB29_RS18525	COG0483	inositol monophosphate 1-phosphatase activity
DB29_RS18550	COG4896	Protein conserved in bacteria
DB29_RS18555	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DB29_RS18560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DB29_RS18565	COG4838	Belongs to the UPF0358 family
DB29_RS18570	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DB29_RS18575	COG1612	heme a metabolic process
DB29_RS18615	COG2340	Cysteine-rich secretory protein family
DB29_RS18645	COG4471	UPF0298 protein
DB29_RS18655	COG0742	ribosomal rna small subunit methyltransferase
DB29_RS18660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DB29_RS18665	COG3314	Sporulation integral membrane protein YlbJ
DB29_RS18670	COG1752	Esterase of the alpha-beta hydrolase superfamily
DB29_RS18675	COG3480	Lon protease (S16) C-terminal proteolytic domain
DB29_RS18680	COG1323	Belongs to the UPF0348 family
DB29_RS18685	COG1399	metal-binding, possibly nucleic acid-binding protein
DB29_RS18690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DB29_RS18700	COG0454	-acetyltransferase
DB29_RS18705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DB29_RS18715	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DB29_RS18720	COG2001	Belongs to the MraZ family
DB29_RS18725	COG0275	rRNA processing
DB29_RS18730	COG4839	cell division protein FtsL
DB29_RS18740	COG0768	penicillin binding
DB29_RS18745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DB29_RS18750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DB29_RS18755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DB29_RS18760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DB29_RS18765	COG0772	Belongs to the SEDS family
DB29_RS18770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DB29_RS18775	COG0849	cell division
DB29_RS18780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DB29_RS18790	COG1191	sigma factor activity
DB29_RS18795	COG1191	sigma factor activity
DB29_RS18800	COG1873	PFAM PRC-barrel domain
DB29_RS18810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DB29_RS18815	COG1799	cell septum assembly
DB29_RS18820	COG0762	integral membrane protein
DB29_RS18825	COG2302	S4 RNA-binding domain
DB29_RS18830	COG3599	regulation of cell shape
DB29_RS18835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DB29_RS18840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DB29_RS18845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DB29_RS18850	COG0564	pseudouridine synthase activity
DB29_RS18855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DB29_RS18860	COG2233	PERMEase
DB29_RS18865	COG0540	Belongs to the ATCase OTCase family
DB29_RS18870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DB29_RS18875	COG0505	Belongs to the CarA family
DB29_RS18880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DB29_RS18885	COG0543	2 iron, 2 sulfur cluster binding
DB29_RS18890	COG0167	dihydroorotate dehydrogenase activity
DB29_RS18895	COG0284	orotidine-5'-phosphate decarboxylase activity
DB29_RS18900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DB29_RS18915	COG4485	Bacterial membrane protein, YfhO
DB29_RS18925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DB29_RS18930	COG2052	Domain of unknown function (DUF370)
DB29_RS18935	COG0194	GDP metabolic process
DB29_RS18940	COG1758	RNA polymerase activity
DB29_RS18945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DB29_RS18950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DB29_RS18955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DB29_RS18960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DB29_RS18960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DB29_RS18965	COG0631	protein serine/threonine phosphatase activity
DB29_RS18970	COG2815	serine threonine protein kinase
DB29_RS18970	COG0515	serine threonine protein kinase
DB29_RS18975	COG1162	GTPase activity
DB29_RS18980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DB29_RS18990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DB29_RS18995	COG1302	Protein conserved in bacteria
DB29_RS19000	COG1461	Dihydroxyacetone kinase
DB29_RS19005	COG1307	EDD domain protein, DegV family
DB29_RS19010	COG1760	l-serine dehydratase
DB29_RS19015	COG1760	l-serine dehydratase
DB29_RS19020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DB29_RS19025	COG1349	DNA-binding transcription factor activity
DB29_RS19030	COG0416	fatty acid biosynthetic process
DB29_RS19035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DB29_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS19045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DB29_RS19050	COG0571	ribonuclease III activity
DB29_RS19065	COG0552	protein localization to endoplasmic reticulum
DB29_RS19070	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DB29_RS19075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DB29_RS19080	COG0228	four-way junction DNA binding
DB29_RS19085	COG1837	Belongs to the UPF0109 family
DB29_RS19095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DB29_RS19100	COG0336	Belongs to the RNA methyltransferase TrmD family
DB29_RS19105	COG0018	arginyl-trna synthetase
DB29_RS19110	COG0335	large ribosomal subunit rRNA binding
DB29_RS19135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DB29_RS19150	COG0045	succinate-CoA ligase (ADP-forming) activity
DB29_RS19155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DB29_RS19160	COG0758	DNA mediated transformation
DB29_RS19165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DB29_RS19170	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DB29_RS19175	COG4974	Belongs to the 'phage' integrase family
DB29_RS19180	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DB29_RS19185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DB29_RS19190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DB29_RS19195	COG1815	bacterial-type flagellum-dependent cell motility
DB29_RS19200	COG1558	bacterial-type flagellum-dependent cell motility
DB29_RS19205	COG1677	Flagellar hook-basal body complex protein FliE
DB29_RS19210	COG1766	The M ring may be actively involved in energy transduction
DB29_RS19215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DB29_RS19220	COG1317	bacterial-type flagellum organization
DB29_RS19225	COG1157	protein secretion by the type III secretion system
DB29_RS19245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DB29_RS19250	COG4786	Flagellar basal body rod
DB29_RS19265	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DB29_RS19270	COG1776	CheC inhibitor of MCP methylation
DB29_RS19270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DB29_RS19275	COG2201	protein-glutamate methylesterase activity
DB29_RS19280	COG3190	flagellar
DB29_RS19285	COG1338	Plays a role in the flagellum-specific transport system
DB29_RS19290	COG1987	bacterial-type flagellum assembly
DB29_RS19295	COG1684	flagellar biosynthetic protein fliR
DB29_RS19300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DB29_RS19305	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DB29_RS19310	COG1419	protein localization to endoplasmic reticulum
DB29_RS19320	COG2201	protein-glutamate methylesterase activity
DB29_RS19330	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DB29_RS19335	COG1191	sigma factor activity
DB29_RS19345	COG0052	Belongs to the universal ribosomal protein uS2 family
DB29_RS19350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DB29_RS19355	COG0528	UMP kinase activity
DB29_RS19360	COG0233	cytoplasmic translational termination
DB29_RS19365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DB29_RS19370	COG4589	Belongs to the CDS family
DB29_RS19375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DB29_RS19380	COG0750	zinc metalloprotease
DB29_RS19385	COG0442	prolyl-tRNA aminoacylation
DB29_RS19390	COG2176	DNA-directed DNA polymerase activity
DB29_RS19395	COG0779	Required for maturation of 30S ribosomal subunits
DB29_RS19400	COG0195	Participates in both transcription termination and antitermination
DB29_RS19405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DB29_RS19410	COG1358	cellular component organization or biogenesis
DB29_RS19415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DB29_RS19425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DB29_RS19430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DB29_RS19435	COG0196	riboflavin kinase activity
DB29_RS19440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DB29_RS19445	COG1185	polyribonucleotide nucleotidyltransferase activity
DB29_RS19450	COG0726	polysaccharide deacetylase
DB29_RS19455	COG0612	Peptidase, M16
DB29_RS19465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DB29_RS19470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DB29_RS19475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DB29_RS19480	COG0527	aspartate kinase activity
DB29_RS19485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB29_RS19490	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DB29_RS19495	COG0740	serine-type endopeptidase activity
DB29_RS19505	COG1674	ftsk spoiiie
DB29_RS19510	COG2188	Transcriptional regulator
DB29_RS19515	COG0612	Peptidase, M16
DB29_RS19520	COG0612	Peptidase, M16
DB29_RS19525	COG0300	oxidoreductase activity
DB29_RS19540	COG1426	Protein conserved in bacteria
DB29_RS19545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DB29_RS19550	COG1546	Belongs to the CinA family
DB29_RS19550	COG1058	Belongs to the CinA family
DB29_RS19555	COG0513	Belongs to the DEAD box helicase family
DB29_RS19560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DB29_RS19585	COG1418	mRNA catabolic process
DB29_RS19590	COG1692	metallophosphoesterase
DB29_RS19595	COG2359	stage V sporulation protein S
DB29_RS19605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DB29_RS19610	COG4550	Control of competence regulator ComK, YlbF/YmcA
DB29_RS19620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DB29_RS19635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DB29_RS19640	COG1923	regulation of RNA biosynthetic process
DB29_RS19650	COG0464	growth
DB29_RS19655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DB29_RS19660	COG0174	glutamine synthetase
DB29_RS19670	COG0277	FAD linked oxidase domain protein
DB29_RS19675	COG0247	lactate metabolic process
DB29_RS19680	COG0277	FAD linked oxidase domain protein
DB29_RS19685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DB29_RS19690	COG0179	Fumarylacetoacetate (FAA) hydrolase
DB29_RS19695	COG1414	Transcriptional regulator
DB29_RS19710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DB29_RS19715	COG2814	Major facilitator Superfamily
DB29_RS19720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DB29_RS19725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DB29_RS19730	COG4224	UPF0291 protein
DB29_RS19735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DB29_RS19745	COG3763	UPF0154 protein
DB29_RS19750	COG1132	(ABC) transporter
DB29_RS19755	COG1132	(ABC) transporter
DB29_RS19775	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DB29_RS19795	COG0464	growth
DB29_RS19800	COG0824	Thioesterase
DB29_RS19805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DB29_RS19825	COG2200	EAL domain
DB29_RS19850	COG0835	chemotaxis
DB29_RS19850	COG0784	Response regulator, receiver
DB29_RS19865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DB29_RS19885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DB29_RS19895	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DB29_RS19905	COG1254	Belongs to the acylphosphatase family
DB29_RS19910	COG1115	amino acid carrier protein
DB29_RS19915	COG2309	aminopeptidase activity
DB29_RS19920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DB29_RS19925	COG0720	synthase
DB29_RS19930	COG0602	queuosine metabolic process
DB29_RS19935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DB29_RS19940	COG2197	response regulator
DB29_RS19945	COG4585	Histidine kinase
DB29_RS19960	COG1131	(ABC) transporter
DB29_RS19965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DB29_RS19965	COG0551	DNA topoisomerase type I activity
DB29_RS19970	COG1764	response to oxidative stress
DB29_RS19980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DB29_RS19990	COG0567	Dehydrogenase, E1 component
DB29_RS19995	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB29_RS20005	COG0488	(ABC) transporter
DB29_RS20010	COG0656	L-ascorbic acid biosynthetic process
DB29_RS20015	COG0514	ATP-dependent DNA helicase (RecQ)
DB29_RS20035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB29_RS20040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DB29_RS20045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DB29_RS20050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DB29_RS20055	COG4876	unkown
DB29_RS20060	COG1960	acyl-CoA dehydrogenase activity
DB29_RS20065	COG3069	C4-dicarboxylate transmembrane transporter activity
DB29_RS20075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DB29_RS20095	COG1396	sequence-specific DNA binding
DB29_RS20145	COG0629	single-stranded DNA binding
DB29_RS20155	COG3331	DNA recombination
DB29_RS20185	COG1595	DNA-templated transcription, initiation
DB29_RS20190	COG0758	DNA mediated transformation
DB29_RS20205	COG3728	DNA packaging
DB29_RS20205	COG5484	DNA packaging
DB29_RS20385	COG4282	regulation of fungal-type cell wall biogenesis
DB29_RS20440	COG0438	transferase activity, transferring glycosyl groups
DB29_RS20455	COG0561	phosphatase activity
DB29_RS20460	COG1263	PTS System
DB29_RS20460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS20465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DB29_RS20495	COG1263	PTS System
DB29_RS20495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB29_RS20500	COG3394	polysaccharide catabolic process
DB29_RS20505	COG1486	melibiose metabolic process
DB29_RS20510	COG2188	Transcriptional regulator
DB29_RS20520	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB29_RS20520	COG2247	cell wall binding repeat
DB29_RS20545	COG0438	transferase activity, transferring glycosyl groups
DB29_RS20550	COG0617	tRNA 3'-terminal CCA addition
DB29_RS20560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DB29_RS20565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DB29_RS20570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DB29_RS20580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DB29_RS20580	COG1199	ATP-dependent helicase activity
DB29_RS20585	COG0402	S-adenosylhomocysteine deaminase activity
DB29_RS20605	COG0017	Asparaginyl-tRNA synthetase
DB29_RS20610	COG3935	DnaD domain protein
DB29_RS20615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DB29_RS20620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DB29_RS20635	COG4499	WXG100 protein secretion system (Wss), protein YukC
DB29_RS20635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB29_RS20640	COG3331	DNA recombination
DB29_RS20650	COG0789	Transcriptional regulator
DB29_RS20665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DB29_RS20670	COG0693	protein deglycase activity
DB29_RS20675	COG1234	tRNA 3'-trailer cleavage
DB29_RS20700	COG1413	lyase activity
DB29_RS20710	COG3402	PFAM membrane-flanked domain
DB29_RS20715	COG3428	Bacterial PH domain
DB29_RS20735	COG0067	glutamate synthase
DB29_RS20735	COG0069	glutamate synthase activity
DB29_RS20735	COG0070	glutamate synthase
DB29_RS20740	COG0493	'glutamate synthase
DB29_RS20770	COG0561	phosphatase activity
DB29_RS20775	COG0346	lactoylglutathione lyase activity
DB29_RS20780	COG0400	carboxylic ester hydrolase activity
DB29_RS20795	COG0814	amino acid
DB29_RS20800	COG0697	spore germination
DB29_RS20810	COG1205	dead DEAH box helicase
DB29_RS20810	COG1111	helicase
DB29_RS20815	COG3359	exonuclease
DB29_RS20825	COG4474	Belongs to the UPF0398 family
DB29_RS20830	COG3599	regulation of cell shape
DB29_RS20835	COG0328	RNA-DNA hybrid ribonuclease activity
DB29_RS20865	COG1070	Carbohydrate kinase
DB29_RS20890	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DB29_RS20900	COG1028	Short-chain dehydrogenase reductase Sdr
DB29_RS20905	COG0517	IMP dehydrogenase activity
DB29_RS20905	COG1125	glycine betaine transport
DB29_RS20915	COG1832	CoA-binding protein
DB29_RS20920	COG0187	DNA topoisomerase II activity
DB29_RS20925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DB29_RS20940	COG0628	permease
DB29_RS20950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DB29_RS20955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB29_RS21060	COG2003	Belongs to the UPF0758 family
DB29_RS21165	COG3584	3D domain protein
DB29_RS21165	COG3583	domain protein
DB29_RS21180	COG0011	TIGRFAM Protein of
DB29_RS21320	COG5583	Uncharacterized small protein (DUF2292)
DB29_RS21335	COG1388	LysM domain
DB29_RS21335	COG3584	3D domain protein
DB29_RS21420	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DB29_RS21455	COG0697	spore germination
DB29_RS21545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DB29_RS21550	COG3883	PFAM NLP P60 protein
DB29_RS21550	COG0791	NLP P60 protein
DB29_RS21680	COG1929	Belongs to the glycerate kinase type-1 family