locus-tag	class	description
NKI27_RS00005	COG0706	membrane insertase activity
NKI27_RS00010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKI27_RS00015	COG0426	domain, Protein
NKI27_RS00015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NKI27_RS00025	COG0445	tRNA wobble uridine modification
NKI27_RS00030	COG0357	Ribosomal RNA small subunit methyltransferase G
NKI27_RS00035	COG1192	Involved in chromosome partitioning
NKI27_RS00040	COG1475	DNA binding
NKI27_RS00050	COG0356	it plays a direct role in the translocation of protons across the membrane
NKI27_RS00060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NKI27_RS00065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKI27_RS00070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKI27_RS00075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKI27_RS00080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKI27_RS00085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NKI27_RS00090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKI27_RS00095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NKI27_RS00115	COG0659	secondary active sulfate transmembrane transporter activity
NKI27_RS00135	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NKI27_RS00145	COG1797	cobyrinic acid a,c-diamide synthase activity
NKI27_RS00195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NKI27_RS00225	COG1773	rubredoxin
NKI27_RS00230	COG1773	rubredoxin
NKI27_RS00235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKI27_RS00285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NKI27_RS00290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKI27_RS00330	COG0811	peptide transport
NKI27_RS00335	COG0811	peptide transport
NKI27_RS00340	COG0848	biopolymer transport protein
NKI27_RS00360	COG3609	addiction module antidote protein, CC2985 family
NKI27_RS00365	COG0488	(ABC) transporter
NKI27_RS00375	COG2095	MarC family integral membrane protein
NKI27_RS00390	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NKI27_RS00395	COG3639	organic phosphonate transmembrane transporter activity
NKI27_RS00400	COG2188	Transcriptional regulator
NKI27_RS00405	COG3624	Phosphonate C-P lyase system protein PhnG
NKI27_RS00410	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
NKI27_RS00415	COG3626	phosphonate metabolism
NKI27_RS00420	COG3627	carbon phosphorus lyase activity
NKI27_RS00425	COG4107	phosphonate C-P lyase system protein PhnK
NKI27_RS00430	COG4778	phosphonate C-P lyase system protein PhnL
NKI27_RS00435	COG3454	Phosphonate metabolism
NKI27_RS00440	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NKI27_RS00445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NKI27_RS00475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKI27_RS00480	COG0583	DNA-binding transcription factor activity
NKI27_RS00490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKI27_RS00500	COG1132	(ABC) transporter
NKI27_RS00510	COG3706	GGDEF domain
NKI27_RS00535	COG0640	Transcriptional regulator
NKI27_RS00540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NKI27_RS00565	COG1178	ABC-type Fe3 transport system permease component
NKI27_RS00570	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NKI27_RS00575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKI27_RS00610	COG0840	transmembrane signaling receptor activity
NKI27_RS00625	COG1320	monovalent cation:proton antiporter activity
NKI27_RS00630	COG2212	antiporter activity
NKI27_RS00635	COG1863	multisubunit Na H antiporter MnhE subunit
NKI27_RS00640	COG0651	ATP synthesis coupled electron transport
NKI27_RS00645	COG1006	Multisubunit Na H antiporter MnhC subunit
NKI27_RS00650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NKI27_RS00650	COG2111	Na H antiporter
NKI27_RS00665	COG2909	trisaccharide binding
NKI27_RS00665	COG2909	trisaccharide binding
NKI27_RS00675	COG3119	arylsulfatase activity
NKI27_RS00685	COG2703	oxygen carrier activity
NKI27_RS00695	COG0545	Peptidyl-prolyl cis-trans isomerase
NKI27_RS00700	COG0583	DNA-binding transcription factor activity
NKI27_RS00705	COG1279	arginine transmembrane transporter activity
NKI27_RS00710	COG2860	membrane
NKI27_RS00770	COG3420	alginic acid biosynthetic process
NKI27_RS00820	COG3119	arylsulfatase activity
NKI27_RS00835	COG0583	DNA-binding transcription factor activity
NKI27_RS00840	COG1252	NADH dehydrogenase
NKI27_RS00855	COG0579	oxidoreductase
NKI27_RS00860	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS00885	COG1280	lysine exporter protein (LysE YggA)
NKI27_RS00930	COG2067	long-chain fatty acid transport protein
NKI27_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NKI27_RS00955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NKI27_RS00955	COG5322	oxidoreductase activity
NKI27_RS00960	COG1017	nitric oxide dioxygenase activity
NKI27_RS00960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKI27_RS00975	COG0748	coenzyme F420 binding
NKI27_RS00990	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NKI27_RS00995	COG0811	peptide transport
NKI27_RS01000	COG0848	biopolymer transport protein
NKI27_RS01010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKI27_RS01015	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NKI27_RS01030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKI27_RS01065	COG0071	Belongs to the small heat shock protein (HSP20) family
NKI27_RS01070	COG2169	Transcriptional regulator
NKI27_RS01070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKI27_RS01090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NKI27_RS01100	COG0443	Heat shock 70 kDa protein
NKI27_RS01130	COG1309	transcriptional regulator
NKI27_RS01135	COG2095	MarC family integral membrane protein
NKI27_RS01155	COG2304	oxidoreductase activity
NKI27_RS01175	COG1902	pentaerythritol trinitrate reductase activity
NKI27_RS01175	COG0446	pyridine nucleotide-disulphide oxidoreductase
NKI27_RS01180	COG0668	transmembrane transport
NKI27_RS01200	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
NKI27_RS01275	COG2217	Heavy metal translocating P-type atpase
NKI27_RS01280	COG0789	Transcriptional regulator
NKI27_RS01310	COG1272	protein, Hemolysin III
NKI27_RS01340	COG1832	CoA-binding protein
NKI27_RS01345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKI27_RS01350	COG0302	gtp cyclohydrolase
NKI27_RS01365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NKI27_RS01395	COG0488	(ABC) transporter
NKI27_RS01400	COG0625	glutathione transferase activity
NKI27_RS01420	COG3005	denitrification pathway
NKI27_RS01430	COG0243	molybdopterin cofactor binding
NKI27_RS01445	COG3850	Histidine kinase
NKI27_RS01450	COG2197	response regulator
NKI27_RS01455	COG0746	molybdenum cofactor guanylyltransferase activity
NKI27_RS01465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NKI27_RS01470	COG0303	'Molybdopterin
NKI27_RS01475	COG0521	Mo-molybdopterin cofactor biosynthetic process
NKI27_RS01490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NKI27_RS01500	COG3071	HemY protein
NKI27_RS01505	COG2959	enzyme of heme biosynthesis
NKI27_RS01515	COG0181	hydroxymethylbilane synthase activity
NKI27_RS01525	COG3275	phosphorelay sensor kinase activity
NKI27_RS01530	COG0165	Argininosuccinate lyase
NKI27_RS01535	COG3706	GGDEF domain
NKI27_RS01550	COG0019	diaminopimelate decarboxylase activity
NKI27_RS01555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NKI27_RS01575	COG2205	protein histidine kinase activity
NKI27_RS01575	COG0784	Response regulator, receiver
NKI27_RS01575	COG2198	Histidine kinase
NKI27_RS01590	COG1120	ATPase activity
NKI27_RS01600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NKI27_RS01610	COG3300	MHYT domain
NKI27_RS01610	COG5001	Diguanylate cyclase
NKI27_RS01620	COG1752	Esterase of the alpha-beta hydrolase superfamily
NKI27_RS01660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NKI27_RS01670	COG0729	surface antigen
NKI27_RS01675	COG2911	Protein conserved in bacteria
NKI27_RS01720	COG4335	DNA alkylation repair
NKI27_RS01735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NKI27_RS01740	COG1127	ABC transporter
NKI27_RS01760	COG0069	glutamate synthase activity
NKI27_RS01785	COG1760	l-serine dehydratase
NKI27_RS01790	COG0657	acetylesterase activity
NKI27_RS01805	COG0668	transmembrane transport
NKI27_RS01840	COG1695	Transcriptional regulator
NKI27_RS01845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKI27_RS01860	COG2183	response to ionizing radiation
NKI27_RS01865	COG2918	glutathione biosynthetic process
NKI27_RS01880	COG0840	transmembrane signaling receptor activity
NKI27_RS01900	COG0204	Acyl-transferase
NKI27_RS01910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NKI27_RS01930	COG2201	protein-glutamate methylesterase activity
NKI27_RS01935	COG2198	Histidine kinase
NKI27_RS01935	COG0784	Response regulator, receiver
NKI27_RS01935	COG0643	Histidine kinase
NKI27_RS01945	COG0840	transmembrane signaling receptor activity
NKI27_RS01965	COG0189	ligase activity
NKI27_RS01975	COG1678	Uncharacterized ACR, COG1678
NKI27_RS01980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKI27_RS01990	COG0540	Belongs to the ATCase OTCase family
NKI27_RS02000	COG2095	MarC family integral membrane protein
NKI27_RS02035	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NKI27_RS02045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NKI27_RS02050	COG1011	Hydrolase
NKI27_RS02065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NKI27_RS02070	COG0742	ribosomal rna small subunit methyltransferase
NKI27_RS02080	COG2884	Cell division ATP-binding protein ftsE
NKI27_RS02085	COG2177	Part of the ABC transporter FtsEX involved in
NKI27_RS02120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NKI27_RS02150	COG2205	protein histidine kinase activity
NKI27_RS02155	COG0745	RESPONSE REGULATOR receiver
NKI27_RS02160	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NKI27_RS02160	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NKI27_RS02170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NKI27_RS02190	COG2885	chlorophyll binding
NKI27_RS02200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NKI27_RS02215	COG1752	Esterase of the alpha-beta hydrolase superfamily
NKI27_RS02220	COG2072	flavoprotein involved in K transport
NKI27_RS02230	COG0210	DNA helicase
NKI27_RS02250	COG1024	Enoyl-CoA hydratase
NKI27_RS02255	COG1024	Enoyl-CoA hydratase
NKI27_RS02260	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS02275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NKI27_RS02290	COG1611	Belongs to the LOG family
NKI27_RS02295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKI27_RS02295	COG0301	tRNA thio-modification
NKI27_RS02315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NKI27_RS02340	COG1454	alcohol dehydrogenase
NKI27_RS02350	COG0697	spore germination
NKI27_RS02355	COG0784	Response regulator, receiver
NKI27_RS02355	COG3437	response regulator, receiver
NKI27_RS02365	COG0686	Belongs to the AlaDH PNT family
NKI27_RS02375	COG0604	alcohol dehydrogenase
NKI27_RS02380	COG0668	transmembrane transport
NKI27_RS02405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NKI27_RS02405	COG0519	Catalyzes the synthesis of GMP from XMP
NKI27_RS02410	COG0395	ABC-type sugar transport system, permease component
NKI27_RS02420	COG3842	ATPase activity
NKI27_RS02425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NKI27_RS02430	COG2315	Protein conserved in bacteria
NKI27_RS02435	COG1794	racemase activity, acting on amino acids and derivatives
NKI27_RS02440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NKI27_RS02470	COG0210	DNA helicase
NKI27_RS02475	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NKI27_RS02490	COG2831	hemolysin activation secretion protein
NKI27_RS02495	COG3210	domain, Protein
NKI27_RS02540	COG0318	PFAM AMP-dependent synthetase and ligase
NKI27_RS02575	COG3118	belongs to the thioredoxin family
NKI27_RS02585	COG0435	Glutathione S-transferase
NKI27_RS02600	COG1272	protein, Hemolysin III
NKI27_RS02605	COG5002	protein histidine kinase activity
NKI27_RS02610	COG0745	RESPONSE REGULATOR receiver
NKI27_RS02615	COG2205	protein histidine kinase activity
NKI27_RS02620	COG0745	RESPONSE REGULATOR receiver
NKI27_RS02635	COG0134	indole-3-glycerol-phosphate synthase activity
NKI27_RS02640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKI27_RS02655	COG0546	phosphoglycolate phosphatase activity
NKI27_RS02660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NKI27_RS02670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NKI27_RS02675	COG3178	'Phosphotransferase
NKI27_RS02680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NKI27_RS02685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NKI27_RS02690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NKI27_RS02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NKI27_RS02700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NKI27_RS02705	COG2363	Small membrane protein
NKI27_RS02715	COG2022	thiamine diphosphate biosynthetic process
NKI27_RS02720	COG1309	transcriptional regulator
NKI27_RS02745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKI27_RS02755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKI27_RS02760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKI27_RS02765	COG1605	Chorismate mutase
NKI27_RS02765	COG0077	Prephenate dehydratase
NKI27_RS02785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKI27_RS02795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NKI27_RS02795	COG0678	peroxiredoxin activity
NKI27_RS02805	COG0786	glutamate:sodium symporter activity
NKI27_RS02845	COG0829	nickel cation binding
NKI27_RS02850	COG0831	urea catabolic process
NKI27_RS02855	COG0832	Belongs to the urease beta subunit family
NKI27_RS02860	COG0804	urea catabolic process
NKI27_RS02865	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NKI27_RS02870	COG0830	nickel cation binding
NKI27_RS02875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NKI27_RS02890	COG0151	Belongs to the GarS family
NKI27_RS02915	COG2264	protein methyltransferase activity
NKI27_RS02925	COG0511	ligase activity, forming carbon-carbon bonds
NKI27_RS02930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NKI27_RS02940	COG5001	Diguanylate cyclase
NKI27_RS02940	COG3300	MHYT domain
NKI27_RS02955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NKI27_RS02970	COG4263	nitrous-oxide reductase activity
NKI27_RS02975	COG0348	domain, Protein
NKI27_RS02975	COG3901	Regulator of nitric oxide reductase transcription
NKI27_RS02990	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS03000	COG0784	Response regulator, receiver
NKI27_RS03000	COG2205	protein histidine kinase activity
NKI27_RS03015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NKI27_RS03045	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NKI27_RS03050	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NKI27_RS03055	COG2814	Major facilitator Superfamily
NKI27_RS03075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKI27_RS03085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKI27_RS03110	COG0006	proline dipeptidase activity
NKI27_RS03115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NKI27_RS03120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NKI27_RS03130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NKI27_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKI27_RS03145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKI27_RS03150	COG0140	phosphoribosyl-ATP diphosphatase activity
NKI27_RS03155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NKI27_RS03160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NKI27_RS03170	COG2226	methyltransferase
NKI27_RS03180	COG0318	PFAM AMP-dependent synthetase and ligase
NKI27_RS03230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKI27_RS03235	COG3268	Saccharopine dehydrogenase
NKI27_RS03315	COG0784	Response regulator, receiver
NKI27_RS03315	COG2198	Histidine kinase
NKI27_RS03315	COG5002	protein histidine kinase activity
NKI27_RS03330	COG0514	ATP-dependent DNA helicase (RecQ)
NKI27_RS03340	COG2205	protein histidine kinase activity
NKI27_RS03350	COG2205	protein histidine kinase activity
NKI27_RS03360	COG2204	response regulator
NKI27_RS03380	COG0789	Transcriptional regulator
NKI27_RS03385	COG1090	epimerase
NKI27_RS03395	COG3706	GGDEF domain
NKI27_RS03425	COG1104	cysteine desulfurase activity
NKI27_RS03445	COG0556	nucleotide-excision repair
NKI27_RS03505	COG0028	Belongs to the TPP enzyme family
NKI27_RS03525	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NKI27_RS03530	COG0733	neurotransmitter:sodium symporter activity
NKI27_RS03540	COG2914	Belongs to the UPF0125 (RnfH) family
NKI27_RS03555	COG0497	DNA recombination
NKI27_RS03560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKI27_RS03565	COG0443	Heat shock 70 kDa protein
NKI27_RS03570	COG0484	heat shock protein binding
NKI27_RS03575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NKI27_RS03580	COG0505	Belongs to the CarA family
NKI27_RS03600	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NKI27_RS03605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKI27_RS03610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKI27_RS03615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKI27_RS03620	COG0149	triose-phosphate isomerase activity
NKI27_RS03625	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NKI27_RS03635	COG0779	Required for maturation of 30S ribosomal subunits
NKI27_RS03640	COG0195	Participates in both transcription termination and antitermination
NKI27_RS03645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKI27_RS03645	COG3064	Membrane
NKI27_RS03650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKI27_RS03655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKI27_RS03660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKI27_RS03665	COG1185	polyribonucleotide nucleotidyltransferase activity
NKI27_RS03670	COG1073	alpha beta
NKI27_RS03750	COG1454	alcohol dehydrogenase
NKI27_RS03755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NKI27_RS03790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NKI27_RS03790	COG1199	ATP-dependent helicase activity
NKI27_RS03835	COG4191	Histidine kinase
NKI27_RS03840	COG0784	Response regulator, receiver
NKI27_RS03850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NKI27_RS03855	COG0557	exoribonuclease II activity
NKI27_RS03860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKI27_RS03865	COG0360	Binds together with S18 to 16S ribosomal RNA
NKI27_RS03870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKI27_RS03880	COG0359	binds to the 23S rRNA
NKI27_RS03885	COG0305	Participates in initiation and elongation during chromosome replication
NKI27_RS03890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKI27_RS03900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NKI27_RS03930	COG5001	Diguanylate cyclase
NKI27_RS03930	COG3300	MHYT domain
NKI27_RS03950	COG0405	Gamma-glutamyltransferase
NKI27_RS04000	COG3239	Fatty acid desaturase
NKI27_RS04005	COG2871	sodium ion transport
NKI27_RS04025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NKI27_RS04085	COG0515	serine threonine protein kinase
NKI27_RS04110	COG1201	RNA secondary structure unwinding
NKI27_RS04165	COG0012	GTP binding
NKI27_RS04170	COG0193	aminoacyl-tRNA hydrolase activity
NKI27_RS04175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NKI27_RS04180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKI27_RS04190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NKI27_RS04195	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NKI27_RS04205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NKI27_RS04210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKI27_RS04215	COG2890	protein-(glutamine-N5) methyltransferase activity
NKI27_RS04220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NKI27_RS04235	COG0583	DNA-binding transcription factor activity
NKI27_RS04240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NKI27_RS04260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NKI27_RS04265	COG2894	cell division
NKI27_RS04270	COG0850	regulation of cytokinetic process
NKI27_RS04275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKI27_RS04285	COG0560	Phosphoserine phosphatase
NKI27_RS04285	COG3830	Belongs to the UPF0237 family
NKI27_RS04290	COG2200	EAL domain
NKI27_RS04300	COG1509	lysine 2,3-aminomutase activity
NKI27_RS04305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKI27_RS04310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NKI27_RS04315	COG0688	phosphatidylethanolamine metabolic process
NKI27_RS04340	COG1162	GTPase activity
NKI27_RS04345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NKI27_RS04355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NKI27_RS04355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NKI27_RS04360	COG0802	atpase or kinase
NKI27_RS04365	COG0860	N-Acetylmuramoyl-L-alanine amidase
NKI27_RS04370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKI27_RS04375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKI27_RS04380	COG1923	regulation of RNA biosynthetic process
NKI27_RS04385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKI27_RS04390	COG0330	HflC and HflK could
NKI27_RS04395	COG0330	HflC and HflK could
NKI27_RS04405	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NKI27_RS04410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NKI27_RS04415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NKI27_RS04420	COG4106	trans-aconitate 2-methyltransferase activity
NKI27_RS04455	COG0579	oxidoreductase
NKI27_RS04460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NKI27_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
NKI27_RS04480	COG3724	N-succinylarginine dihydrolase activity
NKI27_RS04485	COG2988	succinylglutamate desuccinylase activity
NKI27_RS04490	COG4160	amino acid transport
NKI27_RS04540	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NKI27_RS04545	COG4251	negative regulation of phosphorylation
NKI27_RS04545	COG3706	GGDEF domain
NKI27_RS04545	COG5001	Diguanylate cyclase
NKI27_RS04545	COG2203	Gaf domain
NKI27_RS04550	COG1194	a g-specific adenine glycosylase
NKI27_RS04565	COG0131	Imidazoleglycerol-phosphate dehydratase
NKI27_RS04570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NKI27_RS04575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NKI27_RS04580	COG0107	imidazoleglycerol-phosphate synthase activity
NKI27_RS04590	COG2861	carbohydrate metabolic process
NKI27_RS04600	COG4942	peptidase
NKI27_RS04605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NKI27_RS04610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKI27_RS04620	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NKI27_RS04625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NKI27_RS04630	COG0183	Belongs to the thiolase family
NKI27_RS04655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NKI27_RS04665	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS04680	COG2223	nitrite transmembrane transporter activity
NKI27_RS04685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKI27_RS04690	COG2233	PERMEase
NKI27_RS04695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKI27_RS04720	COG2193	ferroxidase activity
NKI27_RS04730	COG1116	anion transmembrane transporter activity
NKI27_RS04735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NKI27_RS04755	COG1120	ATPase activity
NKI27_RS04760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKI27_RS04785	COG4774	siderophore transport
NKI27_RS04805	COG0848	biopolymer transport protein
NKI27_RS04810	COG0811	peptide transport
NKI27_RS04815	COG0811	peptide transport
NKI27_RS04850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NKI27_RS04870	COG0716	FMN binding
NKI27_RS04880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NKI27_RS04885	COG0156	8-amino-7-oxononanoate synthase activity
NKI27_RS04890	COG1073	alpha beta
NKI27_RS04890	COG2226	methyltransferase
NKI27_RS04895	COG1073	alpha beta
NKI27_RS04895	COG2226	methyltransferase
NKI27_RS04900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NKI27_RS04915	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS04920	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS04930	COG1466	dna polymerase III delta subunit
NKI27_RS04940	COG0495	leucyl-tRNA aminoacylation
NKI27_RS04955	COG4535	Mg2 and Co2 transporter CorC
NKI27_RS04960	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NKI27_RS04965	COG1702	phosphate starvation-inducible protein PhoH
NKI27_RS04980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKI27_RS04985	COG0583	DNA-binding transcription factor activity
NKI27_RS04995	COG2130	NADP-dependent
NKI27_RS05005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NKI27_RS05010	COG0513	Belongs to the DEAD box helicase family
NKI27_RS05020	COG3769	mannosylglycerate metabolic process
NKI27_RS05025	COG1215	transferase activity, transferring glycosyl groups
NKI27_RS05030	COG0366	Alpha amylase catalytic
NKI27_RS05050	COG3081	Nucleoid-associated protein
NKI27_RS05060	COG0175	sulfate reduction
NKI27_RS05080	COG0736	holo-[acyl-carrier-protein] synthase activity
NKI27_RS05085	COG5002	protein histidine kinase activity
NKI27_RS05085	COG2205	protein histidine kinase activity
NKI27_RS05085	COG0784	Response regulator, receiver
NKI27_RS05095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKI27_RS05100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKI27_RS05105	COG3956	TIGRFAM MazG family protein
NKI27_RS05110	COG4771	TonB-dependent receptor
NKI27_RS05115	COG5001	Diguanylate cyclase
NKI27_RS05115	COG5002	protein histidine kinase activity
NKI27_RS05120	COG4251	negative regulation of phosphorylation
NKI27_RS05130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NKI27_RS05140	COG0563	adenylate kinase activity
NKI27_RS05145	COG1214	PFAM Peptidase M22, glycoprotease
NKI27_RS05150	COG1968	undecaprenyl-diphosphatase activity
NKI27_RS05160	COG0742	ribosomal rna small subunit methyltransferase
NKI27_RS05165	COG2937	Belongs to the GPAT DAPAT family
NKI27_RS05170	COG1131	(ABC) transporter
NKI27_RS05185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NKI27_RS05210	COG4191	Histidine kinase
NKI27_RS05230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NKI27_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS05270	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS05295	COG0784	Response regulator, receiver
NKI27_RS05295	COG2198	Histidine kinase
NKI27_RS05295	COG2205	protein histidine kinase activity
NKI27_RS05305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKI27_RS05325	COG2161	toxin-antitoxin pair type II binding
NKI27_RS05330	COG4115	mRNA cleavage
NKI27_RS05480	COG4372	Transposase
NKI27_RS05550	COG4372	Transposase
NKI27_RS05605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NKI27_RS05670	COG2072	flavoprotein involved in K transport
NKI27_RS05830	COG2003	Belongs to the UPF0758 family
NKI27_RS05855	COG4372	Transposase
NKI27_RS05870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKI27_RS05935	COG2105	PFAM AIG2 family protein
NKI27_RS05950	COG4372	Transposase
NKI27_RS06020	COG2026	Addiction module toxin, RelE StbE family
NKI27_RS06070	COG2161	toxin-antitoxin pair type II binding
NKI27_RS06075	COG4115	mRNA cleavage
NKI27_RS06100	COG3041	Addiction module toxin RelE StbE family
NKI27_RS06125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKI27_RS06130	COG2176	DNA-directed DNA polymerase activity
NKI27_RS06140	COG2840	Smr protein MutS2
NKI27_RS06150	COG0235	Class ii aldolase
NKI27_RS06155	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NKI27_RS06160	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NKI27_RS06205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKI27_RS06220	COG1393	Belongs to the ArsC family
NKI27_RS06235	COG0754	glutathionylspermidine amidase activity
NKI27_RS06240	COG5463	Belongs to the UPF0441 family
NKI27_RS06245	COG3766	membrane
NKI27_RS06260	COG1842	Phage shock protein A
NKI27_RS06265	COG3789	protein conserved in bacteria
NKI27_RS06290	COG0825	malonyl-CoA metabolic process
NKI27_RS06295	COG0037	tRNA processing
NKI27_RS06300	COG0504	CTP synthase activity
NKI27_RS06305	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NKI27_RS06310	COG0148	phosphopyruvate hydratase activity
NKI27_RS06315	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NKI27_RS06320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NKI27_RS06325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NKI27_RS06330	COG0585	pseudouridine synthase activity
NKI27_RS06335	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NKI27_RS06340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NKI27_RS06375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NKI27_RS06390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKI27_RS06395	COG4660	Part of a membrane complex involved in electron transport
NKI27_RS06400	COG4659	FMN binding
NKI27_RS06405	COG4658	electron transport chain
NKI27_RS06410	COG4656	Part of a membrane complex involved in electron transport
NKI27_RS06415	COG2878	Part of a membrane complex involved in electron transport
NKI27_RS06420	COG4657	Part of a membrane complex involved in electron transport
NKI27_RS06425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKI27_RS06425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKI27_RS06430	COG0489	protein tyrosine kinase activity
NKI27_RS06440	COG2010	Cytochrome c
NKI27_RS06450	COG3278	Belongs to the heme-copper respiratory oxidase family
NKI27_RS06460	COG0390	transport system, permease component
NKI27_RS06465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NKI27_RS06470	COG0717	Belongs to the dCTP deaminase family
NKI27_RS06475	COG2814	Major facilitator Superfamily
NKI27_RS06480	COG0235	Class ii aldolase
NKI27_RS06490	COG3977	Valine--pyruvate aminotransferase
NKI27_RS06500	COG2226	methyltransferase
NKI27_RS06510	COG0534	Mate efflux family protein
NKI27_RS06515	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NKI27_RS06525	COG1054	Belongs to the UPF0176 family
NKI27_RS06550	COG2204	response regulator
NKI27_RS06555	COG3706	GGDEF domain
NKI27_RS06560	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS06565	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS06610	COG3706	GGDEF domain
NKI27_RS06615	COG2207	Transcriptional regulator
NKI27_RS06620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NKI27_RS06625	COG2207	Transcriptional regulator
NKI27_RS06635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NKI27_RS06640	COG1070	Carbohydrate kinase
NKI27_RS06645	COG0745	RESPONSE REGULATOR receiver
NKI27_RS06650	COG1666	GTP binding
NKI27_RS06660	COG2814	Major facilitator Superfamily
NKI27_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS06675	COG3030	protein affecting phage T7 exclusion by the F plasmid
NKI27_RS06680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NKI27_RS06685	COG0459	protein refolding
NKI27_RS06705	COG0501	Belongs to the peptidase M48B family
NKI27_RS06710	COG1704	LemA family
NKI27_RS06720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NKI27_RS06730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKI27_RS06805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKI27_RS06810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NKI27_RS06815	COG0705	Rhomboid family
NKI27_RS06830	COG0308	aminopeptidase N
NKI27_RS06850	COG2358	TRAP transporter, solute receptor (TAXI family
NKI27_RS06860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKI27_RS06865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NKI27_RS06870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NKI27_RS06875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NKI27_RS06880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NKI27_RS06885	COG0072	phenylalanine-tRNA ligase activity
NKI27_RS06885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKI27_RS06890	COG0776	regulation of translation
NKI27_RS06915	COG4372	Transposase
NKI27_RS06980	COG1797	cobyrinic acid a,c-diamide synthase activity
NKI27_RS06990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NKI27_RS07050	COG1492	cobalamin metabolic process
NKI27_RS07055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NKI27_RS07085	COG0625	glutathione transferase activity
NKI27_RS07100	COG0514	ATP-dependent DNA helicase (RecQ)
NKI27_RS07105	COG1322	Protein conserved in bacteria
NKI27_RS07110	COG5002	protein histidine kinase activity
NKI27_RS07110	COG5001	Diguanylate cyclase
NKI27_RS07120	COG0714	Associated with various cellular activities
NKI27_RS07140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NKI27_RS07140	COG1648	precorrin-2 dehydrogenase activity
NKI27_RS07145	COG0535	radical SAM domain protein
NKI27_RS07175	COG2010	Cytochrome c
NKI27_RS07195	COG2010	Cytochrome c
NKI27_RS07230	COG1639	'signal transduction protein
NKI27_RS07245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKI27_RS07255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NKI27_RS07260	COG5002	protein histidine kinase activity
NKI27_RS07280	COG0271	Belongs to the BolA IbaG family
NKI27_RS07285	COG0009	L-threonylcarbamoyladenylate synthase
NKI27_RS07300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKI27_RS07350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NKI27_RS07385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NKI27_RS07400	COG0318	PFAM AMP-dependent synthetase and ligase
NKI27_RS07405	COG0673	inositol 2-dehydrogenase activity
NKI27_RS07410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKI27_RS07435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKI27_RS07445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NKI27_RS07455	COG0123	including yeast histone deacetylase and acetoin utilization protein
NKI27_RS07460	COG0045	succinate-CoA ligase (ADP-forming) activity
NKI27_RS07460	COG1042	CoA-binding domain protein
NKI27_RS07460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NKI27_RS07465	COG2974	May be involved in recombination
NKI27_RS07475	COG3022	response to hydroperoxide
NKI27_RS07500	COG2304	oxidoreductase activity
NKI27_RS07520	COG0714	Associated with various cellular activities
NKI27_RS07540	COG0442	prolyl-tRNA aminoacylation
NKI27_RS07545	COG1570	exodeoxyribonuclease VII activity
NKI27_RS07555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NKI27_RS07555	COG0519	Catalyzes the synthesis of GMP from XMP
NKI27_RS07595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NKI27_RS07600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NKI27_RS07605	COG0632	four-way junction helicase activity
NKI27_RS07610	COG2255	four-way junction helicase activity
NKI27_RS07615	COG0824	Thioesterase
NKI27_RS07635	COG0823	Involved in the tonB-independent uptake of proteins
NKI27_RS07635	COG5616	cAMP biosynthetic process
NKI27_RS07640	COG2885	chlorophyll binding
NKI27_RS07645	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NKI27_RS07660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NKI27_RS07670	COG0425	Belongs to the sulfur carrier protein TusA family
NKI27_RS07685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NKI27_RS07690	COG2716	regulation of RNA biosynthetic process
NKI27_RS07695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKI27_RS07705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NKI27_RS07795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NKI27_RS07805	COG1106	Psort location Cytoplasmic, score
NKI27_RS07860	COG2827	Endonuclease containing a URI domain
NKI27_RS07895	COG4804	nuclease activity
NKI27_RS07995	COG0631	protein serine/threonine phosphatase activity
NKI27_RS08010	COG4120	Belongs to the binding-protein-dependent transport system permease family
NKI27_RS08030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NKI27_RS08035	COG1840	ABC-type Fe3 transport system, periplasmic component
NKI27_RS08060	COG1131	(ABC) transporter
NKI27_RS08065	COG0842	Transport permease protein
NKI27_RS08070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKI27_RS08070	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKI27_RS08080	COG0778	Nitroreductase
NKI27_RS08090	COG1815	bacterial-type flagellum-dependent cell motility
NKI27_RS08100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NKI27_RS08110	COG4787	bacterial-type flagellum-dependent cell motility
NKI27_RS08120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NKI27_RS08125	COG1706	bacterial-type flagellum-dependent cell motility
NKI27_RS08150	COG1741	Belongs to the pirin family
NKI27_RS08160	COG1741	Belongs to the pirin family
NKI27_RS08165	COG1741	Belongs to the pirin family
NKI27_RS08170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKI27_RS08190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NKI27_RS08195	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKI27_RS08200	COG0343	queuine tRNA-ribosyltransferase activity
NKI27_RS08205	COG1862	Preprotein translocase
NKI27_RS08245	COG0105	UTP biosynthetic process
NKI27_RS08250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NKI27_RS08260	COG1426	Protein conserved in bacteria
NKI27_RS08265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NKI27_RS08270	COG0124	histidyl-tRNA synthetase
NKI27_RS08275	COG2976	Protein conserved in bacteria
NKI27_RS08295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKI27_RS08310	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NKI27_RS08340	COG0784	Response regulator, receiver
NKI27_RS08340	COG0835	chemotaxis
NKI27_RS08345	COG0633	Ferredoxin
NKI27_RS08345	COG3217	Mosc domain protein beta barrel domain protein
NKI27_RS08355	COG0488	(ABC) transporter
NKI27_RS08365	COG0589	response to stress
NKI27_RS08380	COG1024	Enoyl-CoA hydratase
NKI27_RS08380	COG1250	3-hydroxyacyl-CoA dehydrogenase
NKI27_RS08385	COG0183	Belongs to the thiolase family
NKI27_RS08410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NKI27_RS08415	COG1053	succinate dehydrogenase
NKI27_RS08420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NKI27_RS08440	COG0045	succinate-CoA ligase (ADP-forming) activity
NKI27_RS08450	COG0180	Tryptophanyl-tRNA synthetase
NKI27_RS08455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKI27_RS08460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKI27_RS08470	COG3706	GGDEF domain
NKI27_RS08480	COG1196	nuclear chromosome segregation
NKI27_RS08485	COG3115	cell septum assembly
NKI27_RS08490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NKI27_RS08495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NKI27_RS08495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NKI27_RS08500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKI27_RS08505	COG3706	GGDEF domain
NKI27_RS08530	COG0835	chemotaxis
NKI27_RS08530	COG0784	Response regulator, receiver
NKI27_RS08535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NKI27_RS08545	COG1595	DNA-templated transcription, initiation
NKI27_RS08550	COG0415	Belongs to the DNA photolyase family
NKI27_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS08580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NKI27_RS08595	COG0488	(ABC) transporter
NKI27_RS08605	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS08615	COG2133	pyrroloquinoline quinone binding
NKI27_RS08635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NKI27_RS08655	COG1959	2 iron, 2 sulfur cluster binding
NKI27_RS08660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKI27_RS08660	COG1017	nitric oxide dioxygenase activity
NKI27_RS08665	COG2204	response regulator
NKI27_RS08670	COG3852	Histidine kinase
NKI27_RS08675	COG1271	oxidase subunit
NKI27_RS08680	COG1294	oxidase, subunit
NKI27_RS08685	COG0667	Aldo Keto reductase
NKI27_RS08690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKI27_RS08690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKI27_RS08695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKI27_RS08700	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKI27_RS08705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NKI27_RS08710	COG3100	YcgL domain-containing protein
NKI27_RS08715	COG2983	Belongs to the UPF0260 family
NKI27_RS08735	COG0121	glutamine amidotransferase
NKI27_RS08740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NKI27_RS08745	COG0542	response to heat
NKI27_RS08780	COG0811	peptide transport
NKI27_RS08800	COG2030	dehydratase
NKI27_RS08805	COG2267	carboxylic ester hydrolase activity
NKI27_RS08810	COG0318	PFAM AMP-dependent synthetase and ligase
NKI27_RS08815	COG1643	Atp-dependent helicase
NKI27_RS08835	COG3267	Type II secretory pathway component ExeA
NKI27_RS08835	COG3409	Peptidoglycan-binding domain 1 protein
NKI27_RS08845	COG1199	ATP-dependent helicase activity
NKI27_RS08855	COG0730	response to heat
NKI27_RS08935	COG0084	hydrolase, TatD family'
NKI27_RS08940	COG2267	carboxylic ester hydrolase activity
NKI27_RS08960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKI27_RS08965	COG2814	Major facilitator Superfamily
NKI27_RS08975	COG3243	poly(R)-hydroxyalkanoic acid synthase
NKI27_RS08980	COG0583	DNA-binding transcription factor activity
NKI27_RS08985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKI27_RS08990	COG0066	3-isopropylmalate dehydratase activity
NKI27_RS08995	COG0473	3-isopropylmalate dehydrogenase activity
NKI27_RS09015	COG0135	phosphoribosylanthranilate isomerase activity
NKI27_RS09025	COG0159	tryptophan synthase activity
NKI27_RS09030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NKI27_RS09035	COG0285	dihydrofolate synthase activity
NKI27_RS09045	COG1286	toxin biosynthetic process
NKI27_RS09060	COG1674	ftsk spoiiie
NKI27_RS09065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NKI27_RS09070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NKI27_RS09075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKI27_RS09080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NKI27_RS09085	COG1648	precorrin-2 dehydrogenase activity
NKI27_RS09085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NKI27_RS09090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKI27_RS09120	COG4172	Belongs to the ABC transporter superfamily
NKI27_RS09125	COG4239	(ABC) transporter, permease
NKI27_RS09130	COG4174	ABC transporter (Permease)
NKI27_RS09135	COG4166	transmembrane transport
NKI27_RS09140	COG4166	transmembrane transport
NKI27_RS09150	COG0741	lytic transglycosylase activity
NKI27_RS09150	COG1388	LysM domain
NKI27_RS09155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NKI27_RS09180	COG0616	signal peptide processing
NKI27_RS09195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKI27_RS09205	COG0316	Belongs to the HesB IscA family
NKI27_RS09205	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NKI27_RS09220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKI27_RS09225	COG2920	part of a sulfur-relay system
NKI27_RS09230	COG2168	tRNA wobble position uridine thiolation
NKI27_RS09235	COG2923	Belongs to the DsrF TusC family
NKI27_RS09240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NKI27_RS09270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKI27_RS09295	COG0582	viral genome integration into host DNA
NKI27_RS09305	COG0582	viral genome integration into host DNA
NKI27_RS09315	COG0582	viral genome integration into host DNA
NKI27_RS09335	COG1484	DNA-dependent DNA replication
NKI27_RS09340	COG4584	PFAM Integrase catalytic
NKI27_RS09365	COG0582	viral genome integration into host DNA
NKI27_RS09385	COG1451	nucleotide metabolic process
NKI27_RS09395	COG1979	alcohol dehydrogenase
NKI27_RS09425	COG2850	peptidyl-arginine hydroxylation
NKI27_RS09435	COG2915	High frequency lysogenization protein hflD homolog
NKI27_RS09440	COG0482	sulfurtransferase activity
NKI27_RS09450	COG1187	pseudouridine synthase activity
NKI27_RS09455	COG1278	Cold shock
NKI27_RS09460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NKI27_RS09465	COG0542	response to heat
NKI27_RS09470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKI27_RS09475	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NKI27_RS09480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NKI27_RS09485	COG0492	ferredoxin-NADP+ reductase activity
NKI27_RS09490	COG0714	Associated with various cellular activities
NKI27_RS09495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NKI27_RS09500	COG2957	Belongs to the agmatine deiminase family
NKI27_RS09515	COG4591	ABC-type transport system involved in lipoprotein release permease component
NKI27_RS09520	COG1136	(ABC) transporter
NKI27_RS09530	COG2333	competence protein COMEC
NKI27_RS09530	COG0658	competence protein
NKI27_RS09535	COG0811	peptide transport
NKI27_RS09540	COG0848	biopolymer transport protein
NKI27_RS09545	COG1132	(ABC) transporter
NKI27_RS09550	COG1663	tetraacyldisaccharide 4'-kinase activity
NKI27_RS09555	COG2835	tetraacyldisaccharide 4'-kinase activity
NKI27_RS09560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NKI27_RS09565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKI27_RS09570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NKI27_RS09580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NKI27_RS09585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NKI27_RS09600	COG0489	protein tyrosine kinase activity
NKI27_RS09615	COG1215	transferase activity, transferring glycosyl groups
NKI27_RS09620	COG0438	transferase activity, transferring glycosyl groups
NKI27_RS09630	COG0463	Glycosyl transferase, family 2
NKI27_RS09630	COG1216	Glycosyl transferase, family 2
NKI27_RS09635	COG0726	polysaccharide deacetylase
NKI27_RS09635	COG1649	PFAM Uncharacterised BCR, COG1649
NKI27_RS09640	COG0438	transferase activity, transferring glycosyl groups
NKI27_RS09665	COG0110	maltose O-acetyltransferase activity
NKI27_RS09680	COG0463	Glycosyl transferase, family 2
NKI27_RS09680	COG1216	Glycosyl transferase, family 2
NKI27_RS09690	COG1215	transferase activity, transferring glycosyl groups
NKI27_RS09735	COG2204	response regulator
NKI27_RS09740	COG4191	Histidine kinase
NKI27_RS09750	COG0204	Acyl-transferase
NKI27_RS09755	COG0582	viral genome integration into host DNA
NKI27_RS09765	COG4453	Protein conserved in bacteria
NKI27_RS09835	COG2433	Pfam Transposase IS66
NKI27_RS09910	COG4584	PFAM Integrase catalytic
NKI27_RS09915	COG1484	DNA-dependent DNA replication
NKI27_RS09985	COG2433	Pfam Transposase IS66
NKI27_RS09990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKI27_RS10085	COG1401	restriction endodeoxyribonuclease activity
NKI27_RS10140	COG1309	transcriptional regulator
NKI27_RS10145	COG0708	Exodeoxyribonuclease III
NKI27_RS10155	COG2201	protein-glutamate methylesterase activity
NKI27_RS10165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NKI27_RS10180	COG1104	cysteine desulfurase activity
NKI27_RS10210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NKI27_RS10220	COG4770	biotin carboxylase activity
NKI27_RS10225	COG1024	Enoyl-CoA hydratase
NKI27_RS10230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NKI27_RS10235	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS10310	COG3409	Peptidoglycan-binding domain 1 protein
NKI27_RS10310	COG3267	Type II secretory pathway component ExeA
NKI27_RS10395	COG0419	ATPase involved in DNA repair
NKI27_RS10405	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKI27_RS10430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKI27_RS10450	COG3174	membrane
NKI27_RS10455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NKI27_RS10465	COG0475	glutathione-regulated potassium exporter activity
NKI27_RS10465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NKI27_RS10470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKI27_RS10480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NKI27_RS10485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NKI27_RS10490	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NKI27_RS10520	COG2217	Heavy metal translocating P-type atpase
NKI27_RS10540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKI27_RS10550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKI27_RS10585	COG1230	cation diffusion facilitator family transporter
NKI27_RS10590	COG0789	Transcriptional regulator
NKI27_RS10615	COG0668	transmembrane transport
NKI27_RS10625	COG0835	chemotaxis
NKI27_RS10625	COG0784	Response regulator, receiver
NKI27_RS10635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKI27_RS10685	COG0583	DNA-binding transcription factor activity
NKI27_RS10690	COG4974	Belongs to the 'phage' integrase family
NKI27_RS10695	COG2239	Acts as a magnesium transporter
NKI27_RS10710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NKI27_RS10715	COG0800	Aldolase
NKI27_RS10720	COG0129	dihydroxy-acid dehydratase activity
NKI27_RS10730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NKI27_RS10735	COG0515	serine threonine protein kinase
NKI27_RS10735	COG2815	serine threonine protein kinase
NKI27_RS10740	COG2116	formate transmembrane transporter activity
NKI27_RS10745	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
NKI27_RS10755	COG3128	pkhd-type hydroxylase
NKI27_RS10760	COG4774	siderophore transport
NKI27_RS10775	COG0848	biopolymer transport protein
NKI27_RS10780	COG0811	peptide transport
NKI27_RS10790	COG1902	pentaerythritol trinitrate reductase activity
NKI27_RS10790	COG0446	pyridine nucleotide-disulphide oxidoreductase
NKI27_RS10800	COG0328	RNA-DNA hybrid ribonuclease activity
NKI27_RS10815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKI27_RS10835	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS10845	COG3383	formate dehydrogenase (NAD+) activity
NKI27_RS10950	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS11005	COG1999	signal sequence binding
NKI27_RS11020	COG0745	RESPONSE REGULATOR receiver
NKI27_RS11035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NKI27_RS11040	COG1074	ATP-dependent DNA helicase activity
NKI27_RS11045	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NKI27_RS11060	COG0564	pseudouridine synthase activity
NKI27_RS11075	COG5507	3-demethylubiquinone-9 3-methyltransferase
NKI27_RS11085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NKI27_RS11090	COG1846	Transcriptional regulator
NKI27_RS11095	COG0386	Belongs to the glutathione peroxidase family
NKI27_RS11120	COG0436	Aminotransferase
NKI27_RS11130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NKI27_RS11145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NKI27_RS11155	COG3101	peptidyl-lysine hydroxylation
NKI27_RS11165	COG0425	Belongs to the sulfur carrier protein TusA family
NKI27_RS11180	COG0840	transmembrane signaling receptor activity
NKI27_RS11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NKI27_RS11190	COG3278	Belongs to the heme-copper respiratory oxidase family
NKI27_RS11205	COG2010	Cytochrome c
NKI27_RS11210	COG0348	domain, Protein
NKI27_RS11255	COG0037	tRNA processing
NKI27_RS11260	COG1309	transcriptional regulator
NKI27_RS11265	COG0484	heat shock protein binding
NKI27_RS11295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NKI27_RS11305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NKI27_RS11310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKI27_RS11315	COG0740	serine-type endopeptidase activity
NKI27_RS11320	COG0544	peptidyl-prolyl cis-trans isomerase activity
NKI27_RS11345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKI27_RS11350	COG0215	cysteine-tRNA ligase activity
NKI27_RS11355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKI27_RS11365	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NKI27_RS11390	COG0604	alcohol dehydrogenase
NKI27_RS11390	COG3321	synthase
NKI27_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS11400	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NKI27_RS11405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NKI27_RS11410	COG1063	alcohol dehydrogenase
NKI27_RS11420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NKI27_RS11420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NKI27_RS11425	COG1703	isobutyryl-CoA mutase activity
NKI27_RS11430	COG0604	alcohol dehydrogenase
NKI27_RS11440	COG0501	Belongs to the peptidase M48B family
NKI27_RS11445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKI27_RS11450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKI27_RS11460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NKI27_RS11465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKI27_RS11475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NKI27_RS11480	COG0416	fatty acid biosynthetic process
NKI27_RS11485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NKI27_RS11490	COG1399	metal-binding, possibly nucleic acid-binding protein
NKI27_RS11495	COG0424	maF-like protein
NKI27_RS11510	COG0564	pseudouridine synthase activity
NKI27_RS11515	COG1530	ribonuclease E activity
NKI27_RS11535	COG0613	PHP domain protein
NKI27_RS11540	COG2350	Protein conserved in bacteria
NKI27_RS11555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NKI27_RS11575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NKI27_RS11590	COG1803	Methylglyoxal synthase
NKI27_RS11630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKI27_RS11635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NKI27_RS11640	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NKI27_RS11655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKI27_RS11660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NKI27_RS11670	COG0584	glycerophosphoryl diester phosphodiesterase
NKI27_RS11675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKI27_RS11680	COG2991	Protein conserved in bacteria
NKI27_RS11685	COG1477	protein flavinylation
NKI27_RS11690	COG2871	sodium ion transport
NKI27_RS11695	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NKI27_RS11700	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NKI27_RS11710	COG1805	sodium ion transport
NKI27_RS11715	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NKI27_RS11725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKI27_RS11740	COG0668	transmembrane transport
NKI27_RS11745	COG1472	Belongs to the glycosyl hydrolase 3 family
NKI27_RS11760	COG0004	ammonium transporteR
NKI27_RS11770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NKI27_RS11770	COG0617	tRNA 3'-terminal CCA addition
NKI27_RS11770	COG0517	IMP dehydrogenase activity
NKI27_RS11780	COG0307	riboflavin synthase, alpha
NKI27_RS11785	COG2813	Specifically methylates the guanine in position
NKI27_RS11790	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NKI27_RS11795	COG4628	conserved protein (DUF2132)
NKI27_RS11800	COG0564	pseudouridine synthase activity
NKI27_RS11840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKI27_RS11845	COG1607	acyl-coa hydrolase
NKI27_RS11850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NKI27_RS11855	COG2813	Specifically methylates the guanine in position
NKI27_RS11870	COG0564	pseudouridine synthase activity
NKI27_RS11875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NKI27_RS11880	COG0564	pseudouridine synthase activity
NKI27_RS11885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NKI27_RS11920	COG0454	-acetyltransferase
NKI27_RS11955	COG1278	Cold shock
NKI27_RS11965	COG2095	MarC family integral membrane protein
NKI27_RS11970	COG5322	oxidoreductase activity
NKI27_RS11970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NKI27_RS11975	COG1022	Amp-dependent synthetase and ligase
NKI27_RS11990	COG3768	UPF0283 membrane protein
NKI27_RS11995	COG3106	COG3106 Predicted ATPase
NKI27_RS12045	COG0385	Bile acid
NKI27_RS12050	COG2056	Na+-H+ antiporter family
NKI27_RS12055	COG0583	DNA-binding transcription factor activity
NKI27_RS12060	COG2259	Doxx family
NKI27_RS12065	COG1063	alcohol dehydrogenase
NKI27_RS12075	COG0739	heme binding
NKI27_RS12105	COG2081	HI0933 family
NKI27_RS12115	COG0596	Alpha beta hydrolase
NKI27_RS12125	COG0778	Nitroreductase
NKI27_RS12130	COG3012	SEC-C Motif Domain Protein
NKI27_RS12135	COG2814	Major facilitator Superfamily
NKI27_RS12145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NKI27_RS12150	COG2226	methyltransferase
NKI27_RS12165	COG2824	Alkylphosphonate utilization operon protein PhnA
NKI27_RS12170	COG5265	(ABC) transporter
NKI27_RS12175	COG0023	Translation Initiation Factor
NKI27_RS12185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NKI27_RS12210	COG2201	protein-glutamate methylesterase activity
NKI27_RS12215	COG3706	GGDEF domain
NKI27_RS12220	COG2837	iron assimilation
NKI27_RS12225	COG0326	Molecular chaperone. Has ATPase activity
NKI27_RS12260	COG2204	response regulator
NKI27_RS12315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NKI27_RS12320	COG4181	ATPase activity
NKI27_RS12330	COG0429	hydrolase of the alpha beta-hydrolase fold
NKI27_RS12335	COG0589	response to stress
NKI27_RS12350	COG1362	aminopeptidase activity
NKI27_RS12365	COG0116	Belongs to the methyltransferase superfamily
NKI27_RS12365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NKI27_RS12370	COG3130	regulation of translation
NKI27_RS12375	COG0167	dihydroorotate dehydrogenase activity
NKI27_RS12390	COG0556	nucleotide-excision repair
NKI27_RS12395	COG0436	Aminotransferase
NKI27_RS12410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NKI27_RS12420	COG0776	regulation of translation
NKI27_RS12435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NKI27_RS12440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKI27_RS12445	COG0077	Prephenate dehydratase
NKI27_RS12445	COG1605	Chorismate mutase
NKI27_RS12450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKI27_RS12460	COG3706	GGDEF domain
NKI27_RS12465	COG0788	formyltetrahydrofolate deformylase activity
NKI27_RS12470	COG2154	pterin-4-alpha-carbinolamine dehydratase
NKI27_RS12475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NKI27_RS12475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NKI27_RS12490	COG0137	argininosuccinate synthase activity
NKI27_RS12500	COG0418	dihydroorotase activity
NKI27_RS12505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NKI27_RS12510	COG0450	alkyl hydroperoxide reductase
NKI27_RS12515	COG0653	protein targeting
NKI27_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS12540	COG2925	Exonuclease
NKI27_RS12575	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NKI27_RS12600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKI27_RS12600	COG0047	phosphoribosylformylglycinamidine synthase activity
NKI27_RS12605	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NKI27_RS12610	COG2137	regulation of response to DNA damage stimulus
NKI27_RS12625	COG0183	Belongs to the thiolase family
NKI27_RS12630	COG1024	Enoyl-CoA hydratase
NKI27_RS12630	COG1250	3-hydroxyacyl-CoA dehydrogenase
NKI27_RS12650	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NKI27_RS12655	COG0402	S-adenosylhomocysteine deaminase activity
NKI27_RS12660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NKI27_RS12665	COG0546	phosphoglycolate phosphatase activity
NKI27_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS12675	COG4235	cytochrome complex assembly
NKI27_RS12680	COG3088	subunit of a heme lyase
NKI27_RS12695	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NKI27_RS12715	COG4133	protoheme IX ABC transporter activity
NKI27_RS12735	COG2203	Gaf domain
NKI27_RS12735	COG5001	Diguanylate cyclase
NKI27_RS12735	COG4251	negative regulation of phosphorylation
NKI27_RS12735	COG3706	GGDEF domain
NKI27_RS12745	COG0835	chemotaxis
NKI27_RS12755	COG1192	Involved in chromosome partitioning
NKI27_RS12760	COG1360	Flagellar Motor Protein
NKI27_RS12770	COG2201	protein-glutamate methylesterase activity
NKI27_RS12775	COG2198	Histidine kinase
NKI27_RS12775	COG0784	Response regulator, receiver
NKI27_RS12775	COG0643	Histidine kinase
NKI27_RS12780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NKI27_RS12805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKI27_RS12820	COG1987	bacterial-type flagellum assembly
NKI27_RS12870	COG2201	protein-glutamate methylesterase activity
NKI27_RS12875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NKI27_RS12880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NKI27_RS12885	COG0835	chemotaxis
NKI27_RS12890	COG2198	Histidine kinase
NKI27_RS12890	COG0643	Histidine kinase
NKI27_RS12895	COG0745	RESPONSE REGULATOR receiver
NKI27_RS12930	COG1677	Flagellar hook-basal body complex protein FliE
NKI27_RS12960	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NKI27_RS12970	COG3630	sodium ion export across plasma membrane
NKI27_RS12990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NKI27_RS12995	COG0527	aspartate kinase activity
NKI27_RS13000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKI27_RS13020	COG0795	lipopolysaccharide-transporting ATPase activity
NKI27_RS13025	COG0795	lipopolysaccharide-transporting ATPase activity
NKI27_RS13030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NKI27_RS13045	COG0525	valine-tRNA ligase activity
NKI27_RS13075	COG1940	carbohydrate kinase activity
NKI27_RS13085	COG3725	Membrane protein required for beta-lactamase induction
NKI27_RS13090	COG3023	N-Acetylmuramoyl-L-alanine amidase
NKI27_RS13125	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
NKI27_RS13130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKI27_RS13135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKI27_RS13145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NKI27_RS13150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKI27_RS13160	COG1643	Atp-dependent helicase
NKI27_RS13175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NKI27_RS13200	COG0204	Acyl-transferase
NKI27_RS13230	COG1785	Belongs to the alkaline phosphatase family
NKI27_RS13265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NKI27_RS13280	COG4771	TonB-dependent receptor
NKI27_RS13310	COG1573	uracil-dna glycosylase
NKI27_RS13315	COG0183	Belongs to the thiolase family
NKI27_RS13335	COG3153	acetyltransferase
NKI27_RS13335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NKI27_RS13345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKI27_RS13350	COG0372	Belongs to the citrate synthase family
NKI27_RS13355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NKI27_RS13365	COG0826	peptidase U32
NKI27_RS13390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NKI27_RS13395	COG4191	Histidine kinase
NKI27_RS13400	COG4566	intracellular signal transduction
NKI27_RS13405	COG0739	heme binding
NKI27_RS13420	COG1067	ATP-dependent peptidase activity
NKI27_RS13450	COG0826	peptidase U32
NKI27_RS13455	COG0826	peptidase U32
NKI27_RS13460	COG1242	4 iron, 4 sulfur cluster binding
NKI27_RS13465	COG3154	lipid carrier protein
NKI27_RS13475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKI27_RS13480	COG0439	Biotin carboxylase
NKI27_RS13485	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NKI27_RS13495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NKI27_RS13510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKI27_RS13515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NKI27_RS13520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NKI27_RS13530	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NKI27_RS13535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NKI27_RS13540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NKI27_RS13545	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NKI27_RS13565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NKI27_RS13575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKI27_RS13580	COG0233	cytoplasmic translational termination
NKI27_RS13585	COG0528	UMP kinase activity
NKI27_RS13590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKI27_RS13595	COG0052	Belongs to the universal ribosomal protein uS2 family
NKI27_RS13600	COG0024	Methionine aminopeptidase
NKI27_RS13610	COG0436	Aminotransferase
NKI27_RS13615	COG1393	Belongs to the ArsC family
NKI27_RS13620	COG2171	N-acyltransferase activity
NKI27_RS13625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NKI27_RS13630	COG2226	methyltransferase
NKI27_RS13650	COG2900	Belongs to the SlyX family
NKI27_RS13705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NKI27_RS13730	COG1086	Polysaccharide biosynthesis protein
NKI27_RS13750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NKI27_RS13795	COG1442	glycosyl transferase family 8
NKI27_RS13795	COG1216	Glycosyl transferase, family 2
NKI27_RS13805	COG0463	Glycosyl transferase, family 2
NKI27_RS13815	COG1134	teichoic acid transport
NKI27_RS13845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKI27_RS13865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKI27_RS13880	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NKI27_RS13890	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NKI27_RS13895	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NKI27_RS13900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKI27_RS13950	COG1073	alpha beta
NKI27_RS13950	COG2226	methyltransferase
NKI27_RS13980	COG0463	Glycosyl transferase, family 2
NKI27_RS14035	COG0237	dephospho-CoA kinase activity
NKI27_RS14040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NKI27_RS14050	COG1380	Effector of murein hydrolase LrgA
NKI27_RS14055	COG1346	cytolysis
NKI27_RS14060	COG1720	tRNA m6t6A37 methyltransferase activity
NKI27_RS14075	COG2205	protein histidine kinase activity
NKI27_RS14075	COG5002	protein histidine kinase activity
NKI27_RS14075	COG0784	Response regulator, receiver
NKI27_RS14080	COG0640	Transcriptional regulator
NKI27_RS14115	COG2197	response regulator
NKI27_RS14130	COG0183	Belongs to the thiolase family
NKI27_RS14135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NKI27_RS14155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NKI27_RS14160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKI27_RS14165	COG5007	Belongs to the BolA IbaG family
NKI27_RS14185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NKI27_RS14190	COG1127	ABC transporter
NKI27_RS14215	COG1137	ATPase activity
NKI27_RS14235	COG1660	Displays ATPase and GTPase activities
NKI27_RS14240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKI27_RS14245	COG2239	Acts as a magnesium transporter
NKI27_RS14250	COG3028	Belongs to the UPF0307 family
NKI27_RS14255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NKI27_RS14265	COG1530	ribonuclease E activity
NKI27_RS14270	COG0424	maF-like protein
NKI27_RS14275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NKI27_RS14280	COG1792	Involved in formation and maintenance of cell shape
NKI27_RS14285	COG1077	Cell shape determining protein MreB Mrl
NKI27_RS14290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKI27_RS14295	COG0154	amidase activity
NKI27_RS14300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKI27_RS14305	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NKI27_RS14310	COG1381	Involved in DNA repair and RecF pathway recombination
NKI27_RS14315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKI27_RS14320	COG0571	ribonuclease III activity
NKI27_RS14330	COG0681	Belongs to the peptidase S26 family
NKI27_RS14335	COG0481	GTPase activity
NKI27_RS14345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKI27_RS14395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NKI27_RS14405	COG0824	Thioesterase
NKI27_RS14410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NKI27_RS14430	COG0335	large ribosomal subunit rRNA binding
NKI27_RS14440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKI27_RS14445	COG0228	four-way junction DNA binding
NKI27_RS14450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKI27_RS14460	COG4536	flavin adenine dinucleotide binding
NKI27_RS14475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NKI27_RS14480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NKI27_RS14485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKI27_RS14490	COG3842	ATPase activity
NKI27_RS14495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NKI27_RS14510	COG2205	protein histidine kinase activity
NKI27_RS14515	COG0745	RESPONSE REGULATOR receiver
NKI27_RS14520	COG1047	Peptidyl-prolyl cis-trans
NKI27_RS14550	COG2353	YceI-like domain
NKI27_RS14555	COG3038	cytochrome b561
NKI27_RS14560	COG2199	diguanylate cyclase activity
NKI27_RS14560	COG2200	EAL domain
NKI27_RS14570	COG3091	SprT-like family
NKI27_RS14575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NKI27_RS14580	COG2816	NAD+ diphosphatase activity
NKI27_RS14605	COG3228	Belongs to the MtfA family
NKI27_RS14615	COG0417	DNA replication proofreading
NKI27_RS14630	COG4628	conserved protein (DUF2132)
NKI27_RS14645	COG0488	(ABC) transporter
NKI27_RS14650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NKI27_RS14665	COG0523	cobalamin synthesis protein
NKI27_RS14680	COG0840	transmembrane signaling receptor activity
NKI27_RS14700	COG0697	spore germination
NKI27_RS14705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKI27_RS14730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKI27_RS14740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
NKI27_RS14755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NKI27_RS14770	COG0741	lytic transglycosylase activity
NKI27_RS14790	COG0789	Transcriptional regulator
NKI27_RS14795	COG0484	heat shock protein binding
NKI27_RS14810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKI27_RS14835	COG1280	lysine exporter protein (LysE YggA)
NKI27_RS14900	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NKI27_RS14905	COG1187	pseudouridine synthase activity
NKI27_RS14910	COG0513	Belongs to the DEAD box helicase family
NKI27_RS14930	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NKI27_RS14935	COG0204	Acyl-transferase
NKI27_RS14950	COG1061	Type III restriction enzyme res subunit
NKI27_RS14990	COG0420	3'-5' exonuclease activity
NKI27_RS14995	COG0419	ATPase involved in DNA repair
NKI27_RS15010	COG0513	Belongs to the DEAD box helicase family
NKI27_RS15015	COG0545	Peptidyl-prolyl cis-trans isomerase
NKI27_RS15030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKI27_RS15045	COG1132	(ABC) transporter
NKI27_RS15065	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKI27_RS15075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NKI27_RS15085	COG0668	transmembrane transport
NKI27_RS15115	COG3437	response regulator, receiver
NKI27_RS15115	COG3850	Histidine kinase
NKI27_RS15115	COG4999	Histidine kinase
NKI27_RS15115	COG2205	protein histidine kinase activity
NKI27_RS15120	COG1309	transcriptional regulator
NKI27_RS15130	COG1028	Short-chain dehydrogenase reductase Sdr
NKI27_RS15135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NKI27_RS15140	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS15145	COG1024	Enoyl-CoA hydratase
NKI27_RS15170	COG0583	DNA-binding transcription factor activity
NKI27_RS15180	COG0189	ligase activity
NKI27_RS15190	COG4067	protein conserved in archaea
NKI27_RS15190	COG0189	ligase activity
NKI27_RS15195	COG1376	ErfK ybiS ycfS ynhG family protein
NKI27_RS15205	COG2252	PERMEase
NKI27_RS15210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKI27_RS15230	COG2885	chlorophyll binding
NKI27_RS15240	COG2239	Acts as a magnesium transporter
NKI27_RS15260	COG1285	pathogenesis
NKI27_RS15265	COG1187	pseudouridine synthase activity
NKI27_RS15275	COG0179	Fumarylacetoacetate (FAA) hydrolase
NKI27_RS15280	COG0277	FAD linked oxidase domain protein
NKI27_RS15285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NKI27_RS15290	COG2885	chlorophyll binding
NKI27_RS15300	COG0513	Belongs to the DEAD box helicase family
NKI27_RS15305	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NKI27_RS15305	COG3264	Mechanosensitive ion channel
NKI27_RS15320	COG0191	fructose-bisphosphate aldolase activity
NKI27_RS15325	COG0126	phosphoglycerate kinase activity
NKI27_RS15330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NKI27_RS15335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKI27_RS15370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKI27_RS15375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NKI27_RS15380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NKI27_RS15385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NKI27_RS15390	COG1566	PFAM secretion protein HlyD family protein
NKI27_RS15425	COG4399	Belongs to the UPF0754 family
NKI27_RS15445	COG2766	serine protein kinase
NKI27_RS15450	COG2718	Belongs to the UPF0229 family
NKI27_RS15455	COG2719	SpoVR family
NKI27_RS15470	COG0719	Fe-S assembly protein
NKI27_RS15475	COG0396	ATPase activity
NKI27_RS15480	COG0719	Fe-S assembly protein
NKI27_RS15485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKI27_RS15490	COG0316	Belongs to the HesB IscA family
NKI27_RS15500	COG2166	iron-sulfur cluster assembly
NKI27_RS15520	COG0205	6-phosphofructokinase activity
NKI27_RS15550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NKI27_RS15555	COG1309	transcriptional regulator
NKI27_RS15595	COG0583	DNA-binding transcription factor activity
NKI27_RS15600	COG0439	Biotin carboxylase
NKI27_RS15605	COG0511	ligase activity, forming carbon-carbon bonds
NKI27_RS15605	COG5016	pyruvate
NKI27_RS15610	COG0288	reversible hydration of carbon dioxide
NKI27_RS15615	COG0500	methyltransferase
NKI27_RS15620	COG2314	TM2 domain
NKI27_RS15625	COG3152	Membrane
NKI27_RS15635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKI27_RS15645	COG4807	Protein conserved in bacteria
NKI27_RS15695	COG0500	methyltransferase
NKI27_RS15700	COG0583	DNA-binding transcription factor activity
NKI27_RS15715	COG0515	serine threonine protein kinase
NKI27_RS15715	COG2815	serine threonine protein kinase
NKI27_RS15720	COG2223	nitrite transmembrane transporter activity
NKI27_RS15725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKI27_RS15735	COG0243	molybdopterin cofactor binding
NKI27_RS15740	COG0346	lactoylglutathione lyase activity
NKI27_RS15755	COG0569	domain protein
NKI27_RS15755	COG0189	ligase activity
NKI27_RS15775	COG1187	pseudouridine synthase activity
NKI27_RS15780	COG0217	transcriptional regulatory protein
NKI27_RS15790	COG0668	transmembrane transport
NKI27_RS15820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NKI27_RS15840	COG0321	lipoyl(octanoyl) transferase activity
NKI27_RS15845	COG2921	Belongs to the UPF0250 family
NKI27_RS15855	COG1686	Belongs to the peptidase S11 family
NKI27_RS15860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NKI27_RS15865	COG2951	lytic endotransglycosylase activity
NKI27_RS15870	COG0772	Belongs to the SEDS family
NKI27_RS15875	COG0768	penicillin binding
NKI27_RS15880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKI27_RS15890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKI27_RS15895	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKI27_RS15910	COG0586	Pfam SNARE associated Golgi protein
NKI27_RS15915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NKI27_RS15925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NKI27_RS15935	COG0129	dihydroxy-acid dehydratase activity
NKI27_RS15940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKI27_RS15945	COG0840	transmembrane signaling receptor activity
NKI27_RS15945	COG0840	transmembrane signaling receptor activity
NKI27_RS15950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKI27_RS15955	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKI27_RS15960	COG0730	response to heat
NKI27_RS15980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NKI27_RS15990	COG0142	geranyltranstransferase activity
NKI27_RS15995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NKI27_RS16000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NKI27_RS16005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NKI27_RS16015	COG0352	thiamine-phosphate diphosphorylase activity
NKI27_RS16020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NKI27_RS16025	COG0653	protein targeting
NKI27_RS16030	COG0739	heme binding
NKI27_RS16040	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NKI27_RS16060	COG1181	Belongs to the D-alanine--D-alanine ligase family
NKI27_RS16065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NKI27_RS16070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKI27_RS16075	COG0772	Belongs to the SEDS family
NKI27_RS16080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NKI27_RS16085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKI27_RS16090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NKI27_RS16095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKI27_RS16110	COG0275	rRNA processing
NKI27_RS16115	COG2001	Belongs to the MraZ family
NKI27_RS16125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NKI27_RS16130	COG3107	peptidoglycan biosynthetic process
NKI27_RS16135	COG0792	nuclease activity
NKI27_RS16140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NKI27_RS16145	COG2969	positive regulation of protein catabolic process
NKI27_RS16150	COG0625	glutathione transferase activity
NKI27_RS16155	COG2857	Cytochrome c1
NKI27_RS16160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NKI27_RS16165	COG0723	plastoquinol--plastocyanin reductase activity
NKI27_RS16170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NKI27_RS16175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKI27_RS16180	COG0084	hydrolase, TatD family'
NKI27_RS16185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NKI27_RS16190	COG4191	Histidine kinase
NKI27_RS16195	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NKI27_RS16200	COG0456	acetyltransferase
NKI27_RS16210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKI27_RS16235	COG1183	phosphatidylcholine synthase activity
NKI27_RS16245	COG0028	Belongs to the TPP enzyme family
NKI27_RS16275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NKI27_RS16275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NKI27_RS16290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NKI27_RS16335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NKI27_RS16340	COG1047	Peptidyl-prolyl cis-trans
NKI27_RS16350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NKI27_RS16355	COG0196	riboflavin kinase activity
NKI27_RS16360	COG0728	peptidoglycan biosynthetic process
NKI27_RS16365	COG0268	Binds directly to 16S ribosomal RNA
NKI27_RS16370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKI27_RS16375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NKI27_RS16380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NKI27_RS16385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NKI27_RS16390	COG0142	geranyltranstransferase activity
NKI27_RS16410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NKI27_RS16420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKI27_RS16425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NKI27_RS16440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKI27_RS16440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKI27_RS16445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKI27_RS16450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKI27_RS16455	COG0488	(ABC) transporter
NKI27_RS16475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NKI27_RS16480	COG0493	'glutamate synthase
NKI27_RS16485	COG0067	glutamate synthase
NKI27_RS16485	COG0069	glutamate synthase activity
NKI27_RS16485	COG0070	glutamate synthase
NKI27_RS16495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKI27_RS16500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKI27_RS16555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NKI27_RS16570	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKI27_RS16575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NKI27_RS16600	COG0628	permease
NKI27_RS16605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NKI27_RS16635	COG1444	tRNA N-acetyltransferase activity
NKI27_RS16645	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS16650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NKI27_RS16675	COG0076	glutamate decarboxylase activity
NKI27_RS16690	COG5001	Diguanylate cyclase
NKI27_RS16690	COG2203	Gaf domain
NKI27_RS16690	COG3706	GGDEF domain
NKI27_RS16690	COG4251	negative regulation of phosphorylation
NKI27_RS16695	COG0306	phosphate transporter
NKI27_RS16715	COG1946	Acyl-CoA thioesterase
NKI27_RS16740	COG3161	chorismate lyase activity
NKI27_RS16745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NKI27_RS16770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKI27_RS16775	COG1119	ATPase activity
NKI27_RS16780	COG0745	RESPONSE REGULATOR receiver
NKI27_RS16810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NKI27_RS16815	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NKI27_RS16820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NKI27_RS16825	COG3639	organic phosphonate transmembrane transporter activity
NKI27_RS16830	COG0709	Synthesizes selenophosphate from selenide and ATP
NKI27_RS16835	COG0668	transmembrane transport
NKI27_RS16845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NKI27_RS16850	COG0537	adenosine 5'-monophosphoramidase activity
NKI27_RS16865	COG0704	Plays a role in the regulation of phosphate uptake
NKI27_RS16870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NKI27_RS16875	COG0581	inorganic phosphate transmembrane transporter activity
NKI27_RS16900	COG1607	acyl-coa hydrolase
NKI27_RS16915	COG1765	OsmC-like protein
NKI27_RS16925	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NKI27_RS16930	COG3954	Phosphoribulokinase
NKI27_RS16935	COG5001	Diguanylate cyclase
NKI27_RS16935	COG5002	protein histidine kinase activity
NKI27_RS16945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NKI27_RS16945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NKI27_RS16950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NKI27_RS16960	COG3706	GGDEF domain
NKI27_RS16965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NKI27_RS16975	COG0756	dUTP diphosphatase activity
NKI27_RS16980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKI27_RS16985	COG2003	Belongs to the UPF0758 family
NKI27_RS16990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NKI27_RS16995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NKI27_RS17000	COG0281	malic enzyme
NKI27_RS17010	COG0254	rRNA binding
NKI27_RS17015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKI27_RS17020	COG0018	arginyl-trna synthetase
NKI27_RS17030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NKI27_RS17035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NKI27_RS17050	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
NKI27_RS17055	COG0494	nUDIX hydrolase
NKI27_RS17075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKI27_RS17080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKI27_RS17090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NKI27_RS17095	COG3150	esterase
NKI27_RS17100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NKI27_RS17110	COG0494	nUDIX hydrolase
NKI27_RS17115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NKI27_RS17120	COG1538	Outer membrane efflux protein
NKI27_RS17125	COG1519	Transferase
NKI27_RS17155	COG0438	transferase activity, transferring glycosyl groups
NKI27_RS17160	COG0438	transferase activity, transferring glycosyl groups
NKI27_RS17170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NKI27_RS17205	COG3025	triphosphatase activity
NKI27_RS17215	COG1490	D-aminoacyl-tRNA deacylase activity
NKI27_RS17225	COG1217	gtp-binding protein TYPA
NKI27_RS17230	COG0174	glutamine synthetase
NKI27_RS17240	COG3852	Histidine kinase
NKI27_RS17245	COG2204	response regulator
NKI27_RS17280	COG2165	general secretion pathway protein
NKI27_RS17290	COG1459	type II secretion system
NKI27_RS17295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKI27_RS17305	COG3267	Type II secretory pathway component ExeA
NKI27_RS17305	COG3409	Peptidoglycan-binding domain 1 protein
NKI27_RS17310	COG1450	Type ii and iii secretion system protein
NKI27_RS17345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKI27_RS17355	COG1917	Cupin 2, conserved barrel domain protein
NKI27_RS17360	COG0527	aspartate kinase activity
NKI27_RS17375	COG1882	Formate acetyltransferase
NKI27_RS17380	COG1882	Formate acetyltransferase
NKI27_RS17400	COG2814	Major facilitator Superfamily
NKI27_RS17410	COG0203	ribosomal protein L17
NKI27_RS17415	COG0202	RNA polymerase activity
NKI27_RS17420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKI27_RS17425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NKI27_RS17430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKI27_RS17435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NKI27_RS17445	COG0200	Binds to the 23S rRNA
NKI27_RS17450	COG1841	ribosomal large subunit assembly
NKI27_RS17455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKI27_RS17460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKI27_RS17465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKI27_RS17470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKI27_RS17475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKI27_RS17480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKI27_RS17485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKI27_RS17490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKI27_RS17495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKI27_RS17500	COG0255	Belongs to the universal ribosomal protein uL29 family
NKI27_RS17505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKI27_RS17510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKI27_RS17515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKI27_RS17520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKI27_RS17525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKI27_RS17530	COG0089	rRNA binding
NKI27_RS17535	COG0088	Forms part of the polypeptide exit tunnel
NKI27_RS17540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKI27_RS17545	COG0051	transcription antitermination factor activity, RNA binding
NKI27_RS17550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKI27_RS17555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKI27_RS17560	COG0049	tRNA binding
NKI27_RS17565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NKI27_RS17570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKI27_RS17575	COG0085	RNA polymerase activity
NKI27_RS17580	COG0222	ribosome binding
NKI27_RS17585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKI27_RS17590	COG0081	regulation of translation
NKI27_RS17595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NKI27_RS17640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NKI27_RS17695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKI27_RS17700	COG0739	heme binding
NKI27_RS17710	COG0316	Belongs to the HesB IscA family
NKI27_RS17725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NKI27_RS17735	COG1981	membrane
NKI27_RS17740	COG0352	thiamine-phosphate diphosphorylase activity
NKI27_RS17740	COG0351	phosphomethylpyrimidine kinase
NKI27_RS17745	COG0352	thiamine-phosphate diphosphorylase activity
NKI27_RS17750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NKI27_RS17760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NKI27_RS17790	COG1489	DNA binding
NKI27_RS17795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NKI27_RS17800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKI27_RS17805	COG4191	Histidine kinase
NKI27_RS17810	COG2204	response regulator
NKI27_RS17820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NKI27_RS17825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NKI27_RS17830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NKI27_RS17845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKI27_RS17850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NKI27_RS17855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKI27_RS17860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NKI27_RS17865	COG1610	YqeY-like protein
NKI27_RS17975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKI27_RS17980	COG0583	DNA-binding transcription factor activity
NKI27_RS17995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKI27_RS18010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NKI27_RS18015	COG1561	YicC-like family, N-terminal region
NKI27_RS18020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NKI27_RS18045	COG1538	Outer membrane efflux protein
NKI27_RS18055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKI27_RS18090	COG2771	luxR family
NKI27_RS18105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NKI27_RS18125	COG0826	peptidase U32
NKI27_RS18130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NKI27_RS18170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NKI27_RS18175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKI27_RS18180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKI27_RS18180	COG2813	Specifically methylates the guanine in position
NKI27_RS18190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NKI27_RS18195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NKI27_RS18205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NKI27_RS18210	COG0590	tRNA wobble adenosine to inosine editing
NKI27_RS18215	COG0606	chelatase, subunit chli
NKI27_RS18225	COG0347	Belongs to the P(II) protein family
NKI27_RS18230	COG0004	ammonium transporteR
NKI27_RS18235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NKI27_RS18240	COG1166	arginine decarboxylase activity
NKI27_RS18260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NKI27_RS18270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NKI27_RS18280	COG1960	acyl-CoA dehydrogenase activity
NKI27_RS18290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NKI27_RS18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKI27_RS18325	COG4597	amino acid ABC transporter
NKI27_RS18330	COG0765	amino acid transport
NKI27_RS18335	COG1126	abc transporter atp-binding protein
NKI27_RS18370	COG0517	IMP dehydrogenase activity
NKI27_RS18380	COG0596	Alpha beta hydrolase
NKI27_RS18390	COG3647	Membrane
NKI27_RS18400	COG1278	Cold shock
NKI27_RS18415	COG3123	guanosine phosphorylase activity
NKI27_RS18435	COG1278	Cold shock
NKI27_RS18445	COG1671	Belongs to the UPF0178 family
NKI27_RS18535	COG0033	Phosphoglucomutase
NKI27_RS18540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NKI27_RS18550	COG2205	protein histidine kinase activity
NKI27_RS18550	COG3437	response regulator, receiver
NKI27_RS18550	COG3850	Histidine kinase
NKI27_RS18550	COG4999	Histidine kinase
NKI27_RS18555	COG2205	protein histidine kinase activity
NKI27_RS18555	COG3437	response regulator, receiver
NKI27_RS18555	COG3850	Histidine kinase
NKI27_RS18555	COG4999	Histidine kinase
NKI27_RS18565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKI27_RS18570	COG4681	YaeQ
NKI27_RS18595	COG0730	response to heat
NKI27_RS18600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKI27_RS18600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKI27_RS18605	COG0477	Major facilitator Superfamily
NKI27_RS18610	COG1942	4-Oxalocrotonate Tautomerase
NKI27_RS18630	COG1739	Uncharacterized protein family UPF0029
NKI27_RS18635	COG0741	lytic transglycosylase activity
NKI27_RS18645	COG5002	protein histidine kinase activity
NKI27_RS18655	COG2204	response regulator
NKI27_RS18675	COG2197	response regulator
NKI27_RS18680	COG5002	protein histidine kinase activity
NKI27_RS18680	COG5000	phosphorelay sensor kinase activity
NKI27_RS18690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKI27_RS18695	COG0545	Peptidyl-prolyl cis-trans isomerase
NKI27_RS18720	COG3530	Putative quorum-sensing-regulated virulence factor
NKI27_RS18730	COG2832	Protein of unknown function (DUF454)
NKI27_RS18735	COG0617	tRNA 3'-terminal CCA addition
NKI27_RS18735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NKI27_RS18735	COG3620	sequence-specific DNA binding
NKI27_RS18760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKI27_RS18765	COG2354	Protein conserved in bacteria
NKI27_RS18790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKI27_RS18815	COG0579	oxidoreductase
NKI27_RS18850	COG0545	Peptidyl-prolyl cis-trans isomerase
NKI27_RS18875	COG0017	Asparaginyl-tRNA synthetase
NKI27_RS18885	COG0513	Belongs to the DEAD box helicase family
NKI27_RS18900	COG0318	PFAM AMP-dependent synthetase and ligase
NKI27_RS18925	COG2195	Cleaves the N-terminal amino acid of tripeptides
NKI27_RS18965	COG0602	queuosine metabolic process
NKI27_RS18970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NKI27_RS18990	COG2201	protein-glutamate methylesterase activity
NKI27_RS19000	COG0784	Response regulator, receiver
NKI27_RS19000	COG2205	protein histidine kinase activity
NKI27_RS19015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NKI27_RS19025	COG3920	Histidine kinase
NKI27_RS19030	COG0109	protoheme IX farnesyltransferase activity
NKI27_RS19035	COG1612	heme a metabolic process
NKI27_RS19060	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NKI27_RS19070	COG1565	acr, cog1565
NKI27_RS19070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NKI27_RS19075	COG0534	Mate efflux family protein
NKI27_RS19090	COG0339	signal peptide processing
NKI27_RS19095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NKI27_RS19110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NKI27_RS19115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKI27_RS19125	COG0009	L-threonylcarbamoyladenylate synthase
NKI27_RS19130	COG0758	DNA mediated transformation
NKI27_RS19140	COG0242	peptide deformylase activity
NKI27_RS19145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKI27_RS19155	COG0569	domain protein
NKI27_RS19160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NKI27_RS19180	COG0752	glycyl-tRNA synthetase alpha subunit
NKI27_RS19185	COG0751	glycine-tRNA ligase activity
NKI27_RS19190	COG1560	Kdo2-lipid A biosynthetic process
NKI27_RS19210	COG0557	exoribonuclease II activity
NKI27_RS19215	COG1278	Cold shock
NKI27_RS19220	COG0589	response to stress
NKI27_RS19225	COG0589	response to stress
NKI27_RS19230	COG0642	Histidine kinase
NKI27_RS19240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKI27_RS19295	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKI27_RS19305	COG0594	ribonuclease P activity
NKI27_RS19310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane