locus-tag	class	description
MY524_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MY524_RS00025	COG0702	epimerase
MY524_RS00030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MY524_RS00045	COG2350	Protein conserved in bacteria
MY524_RS00050	COG0613	PHP domain protein
MY524_RS00060	COG1530	ribonuclease E activity
MY524_RS00065	COG0564	pseudouridine synthase activity
MY524_RS00085	COG1399	metal-binding, possibly nucleic acid-binding protein
MY524_RS00090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MY524_RS00095	COG0416	fatty acid biosynthetic process
MY524_RS00100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MY524_RS00110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY524_RS00115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MY524_RS00120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MY524_RS00125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MY524_RS00130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MY524_RS00135	COG0501	Belongs to the peptidase M48B family
MY524_RS00145	COG0604	alcohol dehydrogenase
MY524_RS00150	COG1703	isobutyryl-CoA mutase activity
MY524_RS00155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY524_RS00155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY524_RS00165	COG0604	alcohol dehydrogenase
MY524_RS00165	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS00165	COG3321	synthase
MY524_RS00170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MY524_RS00175	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MY524_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS00185	COG0604	alcohol dehydrogenase
MY524_RS00185	COG3321	synthase
MY524_RS00195	COG2239	Acts as a magnesium transporter
MY524_RS00210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY524_RS00220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY524_RS00225	COG0215	cysteine-tRNA ligase activity
MY524_RS00230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MY524_RS00255	COG0544	peptidyl-prolyl cis-trans isomerase activity
MY524_RS00260	COG0740	serine-type endopeptidase activity
MY524_RS00265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MY524_RS00270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MY524_RS00280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY524_RS00305	COG0726	polysaccharide deacetylase
MY524_RS00310	COG0484	heat shock protein binding
MY524_RS00320	COG1309	transcriptional regulator
MY524_RS00325	COG0037	tRNA processing
MY524_RS00340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MY524_RS00370	COG0348	domain, Protein
MY524_RS00375	COG2010	Cytochrome c
MY524_RS00390	COG3278	Belongs to the heme-copper respiratory oxidase family
MY524_RS00395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY524_RS00400	COG0840	transmembrane signaling receptor activity
MY524_RS00405	COG4251	negative regulation of phosphorylation
MY524_RS00405	COG5001	Diguanylate cyclase
MY524_RS00405	COG3706	GGDEF domain
MY524_RS00405	COG2203	Gaf domain
MY524_RS00430	COG3101	peptidyl-lysine hydroxylation
MY524_RS00440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY524_RS00455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MY524_RS00465	COG0436	Aminotransferase
MY524_RS00475	COG1082	Xylose isomerase domain protein TIM barrel
MY524_RS00525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MY524_RS00540	COG1166	arginine decarboxylase activity
MY524_RS00555	COG0386	Belongs to the glutathione peroxidase family
MY524_RS00560	COG1846	Transcriptional regulator
MY524_RS00575	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MY524_RS00580	COG1074	ATP-dependent DNA helicase activity
MY524_RS00585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MY524_RS00605	COG0745	RESPONSE REGULATOR receiver
MY524_RS00620	COG1999	signal sequence binding
MY524_RS00650	COG0659	secondary active sulfate transmembrane transporter activity
MY524_RS00680	COG0583	DNA-binding transcription factor activity
MY524_RS00685	COG1960	acyl-CoA dehydrogenase activity
MY524_RS00690	COG0022	dehydrogenase e1 component
MY524_RS00775	COG4372	Transposase
MY524_RS00870	COG1012	belongs to the aldehyde dehydrogenase family
MY524_RS00880	COG1121	(ABC) transporter
MY524_RS00885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MY524_RS00900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MY524_RS00905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY524_RS00925	COG0730	response to heat
MY524_RS00940	COG0583	DNA-binding transcription factor activity
MY524_RS01000	COG1595	DNA-templated transcription, initiation
MY524_RS01010	COG0674	pyruvate-flavodoxin oxidoreductase activity
MY524_RS01010	COG1013	pyruvate-flavodoxin oxidoreductase activity
MY524_RS01010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MY524_RS01010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MY524_RS01020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MY524_RS01025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MY524_RS01025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MY524_RS01030	COG0529	Catalyzes the synthesis of activated sulfate
MY524_RS01035	COG0471	metal ion transport
MY524_RS01035	COG3273	potassium ion transport
MY524_RS01040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY524_RS01065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MY524_RS01070	COG1587	Uroporphyrinogen-III synthase
MY524_RS01080	COG0438	transferase activity, transferring glycosyl groups
MY524_RS01110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS01120	COG2244	polysaccharide biosynthetic process
MY524_RS01140	COG0463	Glycosyl transferase, family 2
MY524_RS01170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MY524_RS01195	COG0489	protein tyrosine kinase activity
MY524_RS01200	COG3267	Type II secretory pathway component ExeA
MY524_RS01200	COG3409	Peptidoglycan-binding domain 1 protein
MY524_RS01275	COG1960	acyl-CoA dehydrogenase activity
MY524_RS01280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY524_RS01285	COG1024	Enoyl-CoA hydratase
MY524_RS01290	COG4770	biotin carboxylase activity
MY524_RS01300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MY524_RS01335	COG2188	Transcriptional regulator
MY524_RS01340	COG1840	ABC-type Fe3 transport system, periplasmic component
MY524_RS01345	COG3842	ATPase activity
MY524_RS01355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MY524_RS01360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY524_RS01370	COG0560	Phosphoserine phosphatase
MY524_RS01385	COG2062	phosphohistidine phosphatase, SixA
MY524_RS01395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MY524_RS01415	COG0708	Exodeoxyribonuclease III
MY524_RS01420	COG1309	transcriptional regulator
MY524_RS01435	COG0204	Acyl-transferase
MY524_RS01450	COG4191	Histidine kinase
MY524_RS01455	COG2204	response regulator
MY524_RS01485	COG4974	Belongs to the 'phage' integrase family
MY524_RS01495	COG0800	Aldolase
MY524_RS01500	COG0129	dihydroxy-acid dehydratase activity
MY524_RS01505	COG0363	glucosamine-6-phosphate deaminase activity
MY524_RS01510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MY524_RS01515	COG2116	formate transmembrane transporter activity
MY524_RS01520	COG2815	serine threonine protein kinase
MY524_RS01520	COG0515	serine threonine protein kinase
MY524_RS01525	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MY524_RS01530	COG0071	Belongs to the small heat shock protein (HSP20) family
MY524_RS01540	COG1902	pentaerythritol trinitrate reductase activity
MY524_RS01540	COG0446	pyridine nucleotide-disulphide oxidoreductase
MY524_RS01550	COG0328	RNA-DNA hybrid ribonuclease activity
MY524_RS01570	COG1196	nuclear chromosome segregation
MY524_RS01570	COG0741	lytic transglycosylase activity
MY524_RS01570	COG0739	heme binding
MY524_RS01580	COG1960	acyl-CoA dehydrogenase activity
MY524_RS01600	COG1215	transferase activity, transferring glycosyl groups
MY524_RS01610	COG1216	Glycosyl transferase, family 2
MY524_RS01665	COG0463	Glycosyl transferase, family 2
MY524_RS01675	COG0438	transferase activity, transferring glycosyl groups
MY524_RS01680	COG0438	transferase activity, transferring glycosyl groups
MY524_RS01695	COG0463	Glycosyl transferase, family 2
MY524_RS01695	COG1216	Glycosyl transferase, family 2
MY524_RS01705	COG1215	transferase activity, transferring glycosyl groups
MY524_RS01740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY524_RS01745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MY524_RS01755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MY524_RS01760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MY524_RS01765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MY524_RS01770	COG2835	tetraacyldisaccharide 4'-kinase activity
MY524_RS01775	COG1663	tetraacyldisaccharide 4'-kinase activity
MY524_RS01780	COG1132	(ABC) transporter
MY524_RS01785	COG0848	biopolymer transport protein
MY524_RS01790	COG0811	peptide transport
MY524_RS01795	COG0658	competence protein
MY524_RS01795	COG2333	competence protein COMEC
MY524_RS01805	COG1136	(ABC) transporter
MY524_RS01810	COG4591	ABC-type transport system involved in lipoprotein release permease component
MY524_RS01825	COG2957	Belongs to the agmatine deiminase family
MY524_RS01835	COG0714	Associated with various cellular activities
MY524_RS01840	COG0492	ferredoxin-NADP+ reductase activity
MY524_RS01845	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MY524_RS01850	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MY524_RS01855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MY524_RS01860	COG0542	response to heat
MY524_RS01865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MY524_RS01885	COG0482	sulfurtransferase activity
MY524_RS01890	COG2915	High frequency lysogenization protein hflD homolog
MY524_RS01900	COG2850	peptidyl-arginine hydroxylation
MY524_RS01935	COG1979	alcohol dehydrogenase
MY524_RS01945	COG0583	DNA-binding transcription factor activity
MY524_RS01950	COG1169	isochorismate synthase
MY524_RS01955	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MY524_RS01965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MY524_RS01970	COG1441	menaquinone biosynthetic process
MY524_RS01985	COG1451	nucleotide metabolic process
MY524_RS02020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MY524_RS02050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MY524_RS02055	COG2923	Belongs to the DsrF TusC family
MY524_RS02070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MY524_RS02075	COG4399	Belongs to the UPF0754 family
MY524_RS02080	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MY524_RS02080	COG0316	Belongs to the HesB IscA family
MY524_RS02090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY524_RS02105	COG0616	signal peptide processing
MY524_RS02130	COG0328	RNA-DNA hybrid ribonuclease activity
MY524_RS02140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY524_RS02145	COG0741	lytic transglycosylase activity
MY524_RS02145	COG1388	LysM domain
MY524_RS02155	COG4166	transmembrane transport
MY524_RS02160	COG4166	transmembrane transport
MY524_RS02165	COG4174	ABC transporter (Permease)
MY524_RS02170	COG4239	(ABC) transporter, permease
MY524_RS02175	COG4172	Belongs to the ABC transporter superfamily
MY524_RS02210	COG1648	precorrin-2 dehydrogenase activity
MY524_RS02210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MY524_RS02215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MY524_RS02220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MY524_RS02225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MY524_RS02230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MY524_RS02235	COG1674	ftsk spoiiie
MY524_RS02250	COG1286	toxin biosynthetic process
MY524_RS02260	COG0285	dihydrofolate synthase activity
MY524_RS02265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MY524_RS02270	COG0159	tryptophan synthase activity
MY524_RS02280	COG0135	phosphoribosylanthranilate isomerase activity
MY524_RS02300	COG0473	3-isopropylmalate dehydrogenase activity
MY524_RS02305	COG0066	3-isopropylmalate dehydratase activity
MY524_RS02310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MY524_RS02320	COG3243	poly(R)-hydroxyalkanoic acid synthase
MY524_RS02335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MY524_RS02360	COG0084	hydrolase, TatD family'
MY524_RS02440	COG0730	response to heat
MY524_RS02445	COG2909	trisaccharide binding
MY524_RS02450	COG1199	ATP-dependent helicase activity
MY524_RS02455	COG3266	domain, Protein
MY524_RS02470	COG2853	Lipoprotein
MY524_RS02480	COG1643	Atp-dependent helicase
MY524_RS02485	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS02490	COG2267	carboxylic ester hydrolase activity
MY524_RS02495	COG2030	dehydratase
MY524_RS02515	COG0811	peptide transport
MY524_RS02550	COG0542	response to heat
MY524_RS02555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MY524_RS02560	COG0121	glutamine amidotransferase
MY524_RS02580	COG2983	Belongs to the UPF0260 family
MY524_RS02585	COG3100	YcgL domain-containing protein
MY524_RS02590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MY524_RS02595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MY524_RS02600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MY524_RS02605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MY524_RS02610	COG1294	oxidase, subunit
MY524_RS02615	COG1271	oxidase subunit
MY524_RS02620	COG3852	Histidine kinase
MY524_RS02625	COG2204	response regulator
MY524_RS02630	COG0667	Aldo Keto reductase
MY524_RS02640	COG1309	transcriptional regulator
MY524_RS02680	COG1733	regulation of RNA biosynthetic process
MY524_RS02685	COG2267	carboxylic ester hydrolase activity
MY524_RS02735	COG3436	PFAM IS66 Orf2 family protein
MY524_RS02745	COG1960	acyl-CoA dehydrogenase activity
MY524_RS02760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MY524_RS02775	COG4221	oxidoreductase activity
MY524_RS02790	COG0415	Belongs to the DNA photolyase family
MY524_RS02795	COG1595	DNA-templated transcription, initiation
MY524_RS02805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MY524_RS02810	COG0784	Response regulator, receiver
MY524_RS02810	COG0835	chemotaxis
MY524_RS02835	COG2203	Gaf domain
MY524_RS02835	COG3706	GGDEF domain
MY524_RS02835	COG4251	negative regulation of phosphorylation
MY524_RS02835	COG5001	Diguanylate cyclase
MY524_RS02845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MY524_RS02845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MY524_RS02850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MY524_RS02855	COG3115	cell septum assembly
MY524_RS02880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MY524_RS02890	COG0180	Tryptophanyl-tRNA synthetase
MY524_RS02895	COG3344	reverse transcriptase
MY524_RS02915	COG0045	succinate-CoA ligase (ADP-forming) activity
MY524_RS02940	COG1053	succinate dehydrogenase
MY524_RS02945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MY524_RS02970	COG0183	Belongs to the thiolase family
MY524_RS02975	COG1024	Enoyl-CoA hydratase
MY524_RS02975	COG1250	3-hydroxyacyl-CoA dehydrogenase
MY524_RS02990	COG0589	response to stress
MY524_RS03000	COG0488	(ABC) transporter
MY524_RS03010	COG0633	Ferredoxin
MY524_RS03010	COG3217	Mosc domain protein beta barrel domain protein
MY524_RS03015	COG0784	Response regulator, receiver
MY524_RS03015	COG0835	chemotaxis
MY524_RS03045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MY524_RS03055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MY524_RS03075	COG2976	Protein conserved in bacteria
MY524_RS03080	COG0124	histidyl-tRNA synthetase
MY524_RS03085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MY524_RS03090	COG1426	Protein conserved in bacteria
MY524_RS03100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MY524_RS03105	COG0105	UTP biosynthetic process
MY524_RS03110	COG1104	cysteine desulfurase activity
MY524_RS03135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MY524_RS03145	COG1862	Preprotein translocase
MY524_RS03150	COG0343	queuine tRNA-ribosyltransferase activity
MY524_RS03155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MY524_RS03185	COG1706	bacterial-type flagellum-dependent cell motility
MY524_RS03190	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MY524_RS03195	COG4786	Flagellar basal body rod
MY524_RS03200	COG4787	bacterial-type flagellum-dependent cell motility
MY524_RS03210	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MY524_RS03220	COG1815	bacterial-type flagellum-dependent cell motility
MY524_RS03240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MY524_RS03240	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MY524_RS03245	COG0842	Transport permease protein
MY524_RS03250	COG1131	(ABC) transporter
MY524_RS03275	COG1840	ABC-type Fe3 transport system, periplasmic component
MY524_RS03280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MY524_RS03300	COG4120	Belongs to the binding-protein-dependent transport system permease family
MY524_RS03310	COG0515	serine threonine protein kinase
MY524_RS03310	COG2815	serine threonine protein kinase
MY524_RS03315	COG0631	protein serine/threonine phosphatase activity
MY524_RS03350	COG0438	transferase activity, transferring glycosyl groups
MY524_RS03430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MY524_RS03440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MY524_RS03445	COG2716	regulation of RNA biosynthetic process
MY524_RS03450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MY524_RS03475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MY524_RS03490	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MY524_RS03500	COG0823	Involved in the tonB-independent uptake of proteins
MY524_RS03500	COG5616	cAMP biosynthetic process
MY524_RS03520	COG0824	Thioesterase
MY524_RS03525	COG2255	four-way junction helicase activity
MY524_RS03530	COG0632	four-way junction helicase activity
MY524_RS03535	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MY524_RS03540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MY524_RS03550	COG0643	Histidine kinase
MY524_RS03550	COG2198	Histidine kinase
MY524_RS03580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MY524_RS03580	COG0519	Catalyzes the synthesis of GMP from XMP
MY524_RS03590	COG1570	exodeoxyribonuclease VII activity
MY524_RS03600	COG0442	prolyl-tRNA aminoacylation
MY524_RS03620	COG0714	Associated with various cellular activities
MY524_RS03640	COG2304	oxidoreductase activity
MY524_RS03660	COG3022	response to hydroperoxide
MY524_RS03670	COG2974	May be involved in recombination
MY524_RS03690	COG0045	succinate-CoA ligase (ADP-forming) activity
MY524_RS03690	COG1042	CoA-binding domain protein
MY524_RS03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MY524_RS03695	COG0123	including yeast histone deacetylase and acetoin utilization protein
MY524_RS03705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MY524_RS03750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY524_RS03855	COG0009	L-threonylcarbamoyladenylate synthase
MY524_RS03860	COG0271	Belongs to the BolA IbaG family
MY524_RS03865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MY524_RS03880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY524_RS03880	COG4191	Histidine kinase
MY524_RS03890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MY524_RS03900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MY524_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS03920	COG1639	'signal transduction protein
MY524_RS03925	COG1234	tRNA 3'-trailer cleavage
MY524_RS03960	COG2010	Cytochrome c
MY524_RS03965	COG2010	Cytochrome c
MY524_RS04000	COG2010	Cytochrome c
MY524_RS04030	COG0535	radical SAM domain protein
MY524_RS04035	COG1648	precorrin-2 dehydrogenase activity
MY524_RS04035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MY524_RS04055	COG0714	Associated with various cellular activities
MY524_RS04070	COG5001	Diguanylate cyclase
MY524_RS04070	COG5002	protein histidine kinase activity
MY524_RS04075	COG1322	Protein conserved in bacteria
MY524_RS04100	COG2199	diguanylate cyclase activity
MY524_RS04100	COG2203	Gaf domain
MY524_RS04155	COG0776	regulation of translation
MY524_RS04160	COG0072	phenylalanine-tRNA ligase activity
MY524_RS04160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY524_RS04165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MY524_RS04170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MY524_RS04175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MY524_RS04180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MY524_RS04185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MY524_RS04195	COG2358	TRAP transporter, solute receptor (TAXI family
MY524_RS04215	COG0308	aminopeptidase N
MY524_RS04230	COG0705	Rhomboid family
MY524_RS04235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MY524_RS04240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MY524_RS04250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MY524_RS04315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MY524_RS04325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MY524_RS04335	COG1704	LemA family
MY524_RS04340	COG0501	Belongs to the peptidase M48B family
MY524_RS04360	COG0459	protein refolding
MY524_RS04365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MY524_RS04370	COG3030	protein affecting phage T7 exclusion by the F plasmid
MY524_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS04385	COG2211	Major facilitator Superfamily
MY524_RS04390	COG1666	GTP binding
MY524_RS04395	COG0745	RESPONSE REGULATOR receiver
MY524_RS04400	COG1070	Carbohydrate kinase
MY524_RS04405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MY524_RS04420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MY524_RS04425	COG2207	Transcriptional regulator
MY524_RS04430	COG3706	GGDEF domain
MY524_RS04515	COG1960	acyl-CoA dehydrogenase activity
MY524_RS04525	COG1054	Belongs to the UPF0176 family
MY524_RS04530	COG3706	GGDEF domain
MY524_RS04540	COG0534	Mate efflux family protein
MY524_RS04550	COG2226	methyltransferase
MY524_RS04560	COG1960	acyl-CoA dehydrogenase activity
MY524_RS04565	COG3977	Valine--pyruvate aminotransferase
MY524_RS04575	COG0235	Class ii aldolase
MY524_RS04580	COG2814	Major facilitator Superfamily
MY524_RS04585	COG0717	Belongs to the dCTP deaminase family
MY524_RS04590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY524_RS04605	COG1442	glycosyl transferase family 8
MY524_RS04605	COG1216	Glycosyl transferase, family 2
MY524_RS04610	COG1215	transferase activity, transferring glycosyl groups
MY524_RS04620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MY524_RS04620	COG0438	transferase activity, transferring glycosyl groups
MY524_RS04645	COG0726	polysaccharide deacetylase
MY524_RS04650	COG4619	ABC transporter
MY524_RS04655	COG0390	transport system, permease component
MY524_RS04670	COG0489	protein tyrosine kinase activity
MY524_RS04675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY524_RS04675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY524_RS04680	COG4657	Part of a membrane complex involved in electron transport
MY524_RS04685	COG2878	Part of a membrane complex involved in electron transport
MY524_RS04690	COG4656	Part of a membrane complex involved in electron transport
MY524_RS04695	COG4658	electron transport chain
MY524_RS04700	COG4659	FMN binding
MY524_RS04705	COG4660	Part of a membrane complex involved in electron transport
MY524_RS04710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MY524_RS04720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MY524_RS04755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MY524_RS04760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MY524_RS04765	COG0585	pseudouridine synthase activity
MY524_RS04770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MY524_RS04775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MY524_RS04780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MY524_RS04785	COG0148	phosphopyruvate hydratase activity
MY524_RS04795	COG0504	CTP synthase activity
MY524_RS04800	COG0037	tRNA processing
MY524_RS04805	COG0825	malonyl-CoA metabolic process
MY524_RS04855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY524_RS04860	COG1393	Belongs to the ArsC family
MY524_RS04875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MY524_RS04930	COG2885	chlorophyll binding
MY524_RS04960	COG0515	serine threonine protein kinase
MY524_RS04960	COG2815	serine threonine protein kinase
MY524_RS04965	COG0631	protein serine/threonine phosphatase activity
MY524_RS04995	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MY524_RS05005	COG2840	Smr protein MutS2
MY524_RS05010	COG0516	GMP reductase activity
MY524_RS05010	COG0517	IMP dehydrogenase activity
MY524_RS05015	COG2176	DNA-directed DNA polymerase activity
MY524_RS05025	COG3706	GGDEF domain
MY524_RS05030	COG2059	Chromate
MY524_RS05040	COG0517	IMP dehydrogenase activity
MY524_RS05045	COG2176	DNA-directed DNA polymerase activity
MY524_RS05050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MY524_RS05065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MY524_RS05075	COG0784	Response regulator, receiver
MY524_RS05075	COG2205	protein histidine kinase activity
MY524_RS05090	COG4251	negative regulation of phosphorylation
MY524_RS05095	COG0784	Response regulator, receiver
MY524_RS05100	COG5001	Diguanylate cyclase
MY524_RS05100	COG5002	protein histidine kinase activity
MY524_RS05140	COG0028	Belongs to the TPP enzyme family
MY524_RS05145	COG3956	TIGRFAM MazG family protein
MY524_RS05150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MY524_RS05155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MY524_RS05165	COG2205	protein histidine kinase activity
MY524_RS05165	COG5002	protein histidine kinase activity
MY524_RS05165	COG0784	Response regulator, receiver
MY524_RS05185	COG0175	sulfate reduction
MY524_RS05195	COG3081	Nucleoid-associated protein
MY524_RS05215	COG0366	Alpha amylase catalytic
MY524_RS05220	COG1215	transferase activity, transferring glycosyl groups
MY524_RS05225	COG3769	mannosylglycerate metabolic process
MY524_RS05240	COG0534	Mate efflux family protein
MY524_RS05245	COG2909	trisaccharide binding
MY524_RS05250	COG0513	Belongs to the DEAD box helicase family
MY524_RS05255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY524_RS05260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY524_RS05275	COG1702	phosphate starvation-inducible protein PhoH
MY524_RS05280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MY524_RS05285	COG4535	Mg2 and Co2 transporter CorC
MY524_RS05340	COG3344	reverse transcriptase
MY524_RS05375	COG0495	leucyl-tRNA aminoacylation
MY524_RS05380	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MY524_RS05385	COG1466	dna polymerase III delta subunit
MY524_RS05400	COG1960	acyl-CoA dehydrogenase activity
MY524_RS05405	COG1960	acyl-CoA dehydrogenase activity
MY524_RS05420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MY524_RS05430	COG2267	carboxylic ester hydrolase activity
MY524_RS05435	COG0156	8-amino-7-oxononanoate synthase activity
MY524_RS05440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MY524_RS05450	COG0716	FMN binding
MY524_RS05465	COG1120	ATPase activity
MY524_RS05470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MY524_RS05480	COG4774	siderophore transport
MY524_RS05490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MY524_RS05495	COG1121	(ABC) transporter
MY524_RS05525	COG0811	peptide transport
MY524_RS05530	COG0811	peptide transport
MY524_RS05535	COG0848	biopolymer transport protein
MY524_RS05560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MY524_RS05565	COG1116	anion transmembrane transporter activity
MY524_RS05600	COG2193	ferroxidase activity
MY524_RS05610	COG2906	2 iron, 2 sulfur cluster binding
MY524_RS05615	COG1492	cobalamin metabolic process
MY524_RS05630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MY524_RS05640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MY524_RS05645	COG2223	nitrite transmembrane transporter activity
MY524_RS05660	COG1960	acyl-CoA dehydrogenase activity
MY524_RS05670	COG0748	coenzyme F420 binding
MY524_RS05680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MY524_RS05725	COG0183	Belongs to the thiolase family
MY524_RS05735	COG1785	Belongs to the alkaline phosphatase family
MY524_RS05740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MY524_RS05745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MY524_RS05755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY524_RS05760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MY524_RS05765	COG4942	peptidase
MY524_RS05775	COG2861	carbohydrate metabolic process
MY524_RS05785	COG0107	imidazoleglycerol-phosphate synthase activity
MY524_RS05790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MY524_RS05795	COG0131	Imidazoleglycerol-phosphate dehydratase
MY524_RS05815	COG2203	Gaf domain
MY524_RS05815	COG5001	Diguanylate cyclase
MY524_RS05815	COG4251	negative regulation of phosphorylation
MY524_RS05815	COG3706	GGDEF domain
MY524_RS05820	COG0745	RESPONSE REGULATOR receiver
MY524_RS05825	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MY524_RS05865	COG4251	negative regulation of phosphorylation
MY524_RS05865	COG2203	Gaf domain
MY524_RS05865	COG3706	GGDEF domain
MY524_RS05865	COG5001	Diguanylate cyclase
MY524_RS05890	COG4160	amino acid transport
MY524_RS05895	COG2988	succinylglutamate desuccinylase activity
MY524_RS05900	COG3724	N-succinylarginine dihydrolase activity
MY524_RS05905	COG1012	belongs to the aldehyde dehydrogenase family
MY524_RS05920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY524_RS05925	COG0840	transmembrane signaling receptor activity
MY524_RS05940	COG0579	oxidoreductase
MY524_RS05980	COG4106	trans-aconitate 2-methyltransferase activity
MY524_RS05985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY524_RS05990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MY524_RS05995	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MY524_RS06005	COG0330	HflC and HflK could
MY524_RS06010	COG0330	HflC and HflK could
MY524_RS06015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MY524_RS06020	COG1923	regulation of RNA biosynthetic process
MY524_RS06025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MY524_RS06030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MY524_RS06035	COG0860	N-Acetylmuramoyl-L-alanine amidase
MY524_RS06040	COG0802	atpase or kinase
MY524_RS06045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MY524_RS06045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MY524_RS06055	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MY524_RS06060	COG1162	GTPase activity
MY524_RS06085	COG0688	phosphatidylethanolamine metabolic process
MY524_RS06090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MY524_RS06095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MY524_RS06100	COG1509	lysine 2,3-aminomutase activity
MY524_RS06125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MY524_RS06130	COG0850	regulation of cytokinetic process
MY524_RS06135	COG2894	cell division
MY524_RS06160	COG1309	transcriptional regulator
MY524_RS06165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MY524_RS06170	COG0583	DNA-binding transcription factor activity
MY524_RS06180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY524_RS06200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MY524_RS06205	COG2890	protein-(glutamine-N5) methyltransferase activity
MY524_RS06210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MY524_RS06215	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MY524_RS06225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MY524_RS06230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MY524_RS06240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MY524_RS06245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MY524_RS06250	COG0193	aminoacyl-tRNA hydrolase activity
MY524_RS06255	COG0012	GTP binding
MY524_RS06260	COG4974	Belongs to the 'phage' integrase family
MY524_RS06415	COG3344	reverse transcriptase
MY524_RS06495	COG5001	Diguanylate cyclase
MY524_RS06495	COG4251	negative regulation of phosphorylation
MY524_RS06495	COG3706	GGDEF domain
MY524_RS06495	COG2203	Gaf domain
MY524_RS06530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY524_RS06535	COG3047	cAMP biosynthetic process
MY524_RS06545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MY524_RS06550	COG0305	Participates in initiation and elongation during chromosome replication
MY524_RS06555	COG0359	binds to the 23S rRNA
MY524_RS06565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MY524_RS06570	COG0360	Binds together with S18 to 16S ribosomal RNA
MY524_RS06575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY524_RS06580	COG0557	exoribonuclease II activity
MY524_RS06655	COG1199	ATP-dependent helicase activity
MY524_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MY524_RS06685	COG0577	efflux transmembrane transporter activity
MY524_RS06685	COG1136	(ABC) transporter
MY524_RS06695	COG0577	efflux transmembrane transporter activity
MY524_RS06695	COG1136	(ABC) transporter
MY524_RS06725	COG4372	Transposase
MY524_RS06730	COG1607	acyl-coa hydrolase
MY524_RS06750	COG0435	Glutathione S-transferase
MY524_RS06755	COG0583	DNA-binding transcription factor activity
MY524_RS06775	COG0247	lactate metabolic process
MY524_RS06780	COG1139	Iron-sulfur cluster binding protein
MY524_RS06850	COG1073	alpha beta
MY524_RS06855	COG1185	polyribonucleotide nucleotidyltransferase activity
MY524_RS06860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MY524_RS06865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MY524_RS06870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MY524_RS06875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MY524_RS06875	COG3064	Membrane
MY524_RS06880	COG0195	Participates in both transcription termination and antitermination
MY524_RS06900	COG0149	triose-phosphate isomerase activity
MY524_RS06905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MY524_RS06910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MY524_RS06915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY524_RS06920	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MY524_RS06930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MY524_RS06940	COG0505	Belongs to the CarA family
MY524_RS06945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MY524_RS06950	COG0484	heat shock protein binding
MY524_RS06955	COG0443	Heat shock 70 kDa protein
MY524_RS06960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MY524_RS06965	COG0497	DNA recombination
MY524_RS06980	COG2914	Belongs to the UPF0125 (RnfH) family
MY524_RS06990	COG0733	neurotransmitter:sodium symporter activity
MY524_RS06995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MY524_RS07030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MY524_RS07035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MY524_RS07100	COG2204	response regulator
MY524_RS07200	COG2207	Transcriptional regulator
MY524_RS07215	COG0071	Belongs to the small heat shock protein (HSP20) family
MY524_RS07240	COG1942	4-Oxalocrotonate Tautomerase
MY524_RS07250	COG1090	epimerase
MY524_RS07255	COG0789	Transcriptional regulator
MY524_RS07275	COG2204	response regulator
MY524_RS07285	COG2205	protein histidine kinase activity
MY524_RS07295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY524_RS07310	COG0514	ATP-dependent DNA helicase (RecQ)
MY524_RS07345	COG0628	permease
MY524_RS07380	COG3706	GGDEF domain
MY524_RS07385	COG3268	Saccharopine dehydrogenase
MY524_RS07390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MY524_RS07405	COG1408	metallophosphoesterase
MY524_RS07440	COG1024	Enoyl-CoA hydratase
MY524_RS07450	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS07460	COG2226	methyltransferase
MY524_RS07470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY524_RS07475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY524_RS07480	COG0140	phosphoribosyl-ATP diphosphatase activity
MY524_RS07485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MY524_RS07490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MY524_RS07500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MY524_RS07520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MY524_RS07525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MY524_RS07530	COG0006	proline dipeptidase activity
MY524_RS07555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MY524_RS07565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MY524_RS07615	COG2814	Major facilitator Superfamily
MY524_RS07620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MY524_RS07625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MY524_RS07665	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MY524_RS07680	COG0784	Response regulator, receiver
MY524_RS07680	COG2205	protein histidine kinase activity
MY524_RS07685	COG1960	acyl-CoA dehydrogenase activity
MY524_RS07700	COG3901	Regulator of nitric oxide reductase transcription
MY524_RS07700	COG0348	domain, Protein
MY524_RS07720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MY524_RS07745	COG5001	Diguanylate cyclase
MY524_RS07745	COG3300	MHYT domain
MY524_RS07755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MY524_RS07760	COG0511	ligase activity, forming carbon-carbon bonds
MY524_RS07770	COG2264	protein methyltransferase activity
MY524_RS07790	COG0138	bifunctional purine biosynthesis protein purh
MY524_RS07795	COG0151	Belongs to the GarS family
MY524_RS07820	COG0786	glutamate:sodium symporter activity
MY524_RS07830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MY524_RS07830	COG0678	peroxiredoxin activity
MY524_RS07840	COG0840	transmembrane signaling receptor activity
MY524_RS07850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MY524_RS07865	COG0077	Prephenate dehydratase
MY524_RS07865	COG1605	Chorismate mutase
MY524_RS07870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY524_RS07875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MY524_RS07880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MY524_RS07905	COG1309	transcriptional regulator
MY524_RS07910	COG2022	thiamine diphosphate biosynthetic process
MY524_RS07920	COG2363	Small membrane protein
MY524_RS07925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MY524_RS07930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MY524_RS07935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MY524_RS07940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY524_RS07945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MY524_RS07950	COG3178	'Phosphotransferase
MY524_RS07965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MY524_RS07970	COG0546	phosphoglycolate phosphatase activity
MY524_RS07975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MY524_RS07985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MY524_RS07990	COG0134	indole-3-glycerol-phosphate synthase activity
MY524_RS08000	COG0625	glutathione transferase activity
MY524_RS08005	COG0625	glutathione transferase activity
MY524_RS08020	COG0745	RESPONSE REGULATOR receiver
MY524_RS08030	COG0745	RESPONSE REGULATOR receiver
MY524_RS08035	COG5002	protein histidine kinase activity
MY524_RS08040	COG0741	lytic transglycosylase activity
MY524_RS08045	COG0435	Glutathione S-transferase
MY524_RS08055	COG3118	belongs to the thioredoxin family
MY524_RS08065	COG3001	Fructosamine kinase
MY524_RS08110	COG0659	secondary active sulfate transmembrane transporter activity
MY524_RS08115	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS08135	COG4269	membrane
MY524_RS08155	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS08170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY524_RS08185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MY524_RS08190	COG0210	DNA helicase
MY524_RS08220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MY524_RS08230	COG1794	racemase activity, acting on amino acids and derivatives
MY524_RS08235	COG2315	Protein conserved in bacteria
MY524_RS08240	COG0516	GMP reductase activity
MY524_RS08240	COG0517	IMP dehydrogenase activity
MY524_RS08250	COG3842	ATPase activity
MY524_RS08255	COG1176	ABC-type spermidine putrescine transport system, permease component I
MY524_RS08260	COG1177	transmembrane transport
MY524_RS08265	COG0519	Catalyzes the synthesis of GMP from XMP
MY524_RS08275	COG1012	belongs to the aldehyde dehydrogenase family
MY524_RS08290	COG0604	alcohol dehydrogenase
MY524_RS08300	COG0686	Belongs to the AlaDH PNT family
MY524_RS08320	COG1272	protein, Hemolysin III
MY524_RS08325	COG1858	cytochrome C peroxidase
MY524_RS08330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MY524_RS08360	COG1454	alcohol dehydrogenase
MY524_RS08395	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MY524_RS08420	COG4191	Histidine kinase
MY524_RS08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY524_RS08425	COG0784	Response regulator, receiver
MY524_RS08425	COG3437	response regulator, receiver
MY524_RS08430	COG0301	tRNA thio-modification
MY524_RS08430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY524_RS08435	COG1611	Belongs to the LOG family
MY524_RS08450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY524_RS08465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MY524_RS08480	COG1960	acyl-CoA dehydrogenase activity
MY524_RS08485	COG1024	Enoyl-CoA hydratase
MY524_RS08490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MY524_RS08510	COG0210	DNA helicase
MY524_RS08525	COG2072	flavoprotein involved in K transport
MY524_RS08530	COG1752	Esterase of the alpha-beta hydrolase superfamily
MY524_RS08565	COG3344	reverse transcriptase
MY524_RS08630	COG2885	chlorophyll binding
MY524_RS08650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MY524_RS08665	COG0745	RESPONSE REGULATOR receiver
MY524_RS08670	COG2205	protein histidine kinase activity
MY524_RS08725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MY524_RS08735	COG2177	Part of the ABC transporter FtsEX involved in
MY524_RS08740	COG2884	Cell division ATP-binding protein ftsE
MY524_RS08745	COG0552	protein localization to endoplasmic reticulum
MY524_RS08750	COG0742	ribosomal rna small subunit methyltransferase
MY524_RS08760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MY524_RS08775	COG1011	Hydrolase
MY524_RS08780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MY524_RS08785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MY524_RS08790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MY524_RS08820	COG1555	photosystem II stabilization
MY524_RS08825	COG2095	MarC family integral membrane protein
MY524_RS08835	COG0540	Belongs to the ATCase OTCase family
MY524_RS08845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MY524_RS08850	COG1678	Uncharacterized ACR, COG1678
MY524_RS08860	COG0189	ligase activity
MY524_RS08880	COG0840	transmembrane signaling receptor activity
MY524_RS08890	COG0643	Histidine kinase
MY524_RS08890	COG2198	Histidine kinase
MY524_RS08895	COG2201	protein-glutamate methylesterase activity
MY524_RS08915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MY524_RS08925	COG0204	Acyl-transferase
MY524_RS08945	COG1309	transcriptional regulator
MY524_RS08950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MY524_RS08960	COG0840	transmembrane signaling receptor activity
MY524_RS08975	COG2918	glutathione biosynthetic process
MY524_RS08985	COG2183	response to ionizing radiation
MY524_RS09005	COG1943	Transposase
MY524_RS09010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY524_RS09015	COG1695	Transcriptional regulator
MY524_RS09140	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MY524_RS09165	COG3850	Histidine kinase
MY524_RS09165	COG3437	response regulator, receiver
MY524_RS09165	COG2205	protein histidine kinase activity
MY524_RS09165	COG4999	Histidine kinase
MY524_RS09175	COG2823	Periplasmic or secreted lipoprotein
MY524_RS09190	COG1597	lipid kinase activity
MY524_RS09190	COG1803	Methylglyoxal synthase
MY524_RS09205	COG1511	domain protein
MY524_RS09205	COG3264	Mechanosensitive ion channel
MY524_RS09225	COG4221	oxidoreductase activity
MY524_RS09235	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
MY524_RS09240	COG0657	acetylesterase activity
MY524_RS09250	COG1760	l-serine dehydratase
MY524_RS09280	COG3274	enterobacterial common antigen metabolic process
MY524_RS09285	COG0069	glutamate synthase activity
MY524_RS09300	COG1127	ABC transporter
MY524_RS09305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MY524_RS09315	COG4335	DNA alkylation repair
MY524_RS09375	COG2205	protein histidine kinase activity
MY524_RS09380	COG0745	RESPONSE REGULATOR receiver
MY524_RS09385	COG2911	Protein conserved in bacteria
MY524_RS09405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MY524_RS09415	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY524_RS09475	COG3344	reverse transcriptase
MY524_RS09535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MY524_RS09550	COG1752	Esterase of the alpha-beta hydrolase superfamily
MY524_RS09560	COG5001	Diguanylate cyclase
MY524_RS09560	COG3300	MHYT domain
MY524_RS09565	COG4206	TonB-dependent receptor
MY524_RS09580	COG1120	ATPase activity
MY524_RS09595	COG0784	Response regulator, receiver
MY524_RS09595	COG2198	Histidine kinase
MY524_RS09595	COG2205	protein histidine kinase activity
MY524_RS09605	COG1011	Hydrolase
MY524_RS09615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MY524_RS09620	COG0019	diaminopimelate decarboxylase activity
MY524_RS09635	COG5002	protein histidine kinase activity
MY524_RS09635	COG5001	Diguanylate cyclase
MY524_RS09635	COG3447	MASE1 domain protein
MY524_RS09640	COG0165	Argininosuccinate lyase
MY524_RS09645	COG3275	phosphorelay sensor kinase activity
MY524_RS09655	COG0181	hydroxymethylbilane synthase activity
MY524_RS09665	COG2959	enzyme of heme biosynthesis
MY524_RS09670	COG3071	HemY protein
MY524_RS09680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MY524_RS09695	COG0521	Mo-molybdopterin cofactor biosynthetic process
MY524_RS09700	COG0303	'Molybdopterin
MY524_RS09705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MY524_RS09710	COG0314	molybdopterin synthase activity
MY524_RS09715	COG0746	molybdenum cofactor guanylyltransferase activity
MY524_RS09730	COG0625	glutathione transferase activity
MY524_RS09740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MY524_RS09750	COG2197	response regulator
MY524_RS09755	COG3850	Histidine kinase
MY524_RS09770	COG0243	molybdopterin cofactor binding
MY524_RS09775	COG0437	4 iron, 4 sulfur cluster binding
MY524_RS09780	COG0348	domain, Protein
MY524_RS09785	COG3043	anaerobic respiration
MY524_RS09790	COG3005	denitrification pathway
MY524_RS09815	COG0488	(ABC) transporter
MY524_RS09850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MY524_RS09865	COG0302	gtp cyclohydrolase
MY524_RS09870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MY524_RS09875	COG1832	CoA-binding protein
MY524_RS09895	COG2827	Endonuclease containing a URI domain
MY524_RS09920	COG1272	protein, Hemolysin III
MY524_RS09950	COG0789	Transcriptional regulator
MY524_RS09955	COG2217	Heavy metal translocating P-type atpase
MY524_RS10000	COG4191	Histidine kinase
MY524_RS10010	COG5001	Diguanylate cyclase
MY524_RS10010	COG4251	negative regulation of phosphorylation
MY524_RS10010	COG2203	Gaf domain
MY524_RS10010	COG3706	GGDEF domain
MY524_RS10025	COG0133	tryptophan synthase activity
MY524_RS10030	COG3549	Plasmid maintenance system killer
MY524_RS10035	COG3093	addiction module antidote protein HigA
MY524_RS10060	COG0534	Mate efflux family protein
MY524_RS10070	COG0500	methyltransferase
MY524_RS10095	COG1902	pentaerythritol trinitrate reductase activity
MY524_RS10095	COG0446	pyridine nucleotide-disulphide oxidoreductase
MY524_RS10135	COG2304	oxidoreductase activity
MY524_RS10155	COG4191	Histidine kinase
MY524_RS10160	COG0604	alcohol dehydrogenase
MY524_RS10160	COG3321	synthase
MY524_RS10160	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS10170	COG2095	MarC family integral membrane protein
MY524_RS10200	COG1309	transcriptional regulator
MY524_RS10215	COG0840	transmembrane signaling receptor activity
MY524_RS10220	COG0443	Heat shock 70 kDa protein
MY524_RS10260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MY524_RS10285	COG2169	Transcriptional regulator
MY524_RS10285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MY524_RS10325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY524_RS10325	COG1017	nitric oxide dioxygenase activity
MY524_RS10330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY524_RS10330	COG5322	oxidoreductase activity
MY524_RS10335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY524_RS10365	COG0471	metal ion transport
MY524_RS10365	COG0490	domain, Protein
MY524_RS10390	COG2814	Major facilitator Superfamily
MY524_RS10410	COG0583	DNA-binding transcription factor activity
MY524_RS10450	COG0348	domain, Protein
MY524_RS10465	COG1280	lysine exporter protein (LysE YggA)
MY524_RS10470	COG0443	Heat shock 70 kDa protein
MY524_RS10475	COG0443	Heat shock 70 kDa protein
MY524_RS10490	COG1162	GTPase activity
MY524_RS10515	COG1252	NADH dehydrogenase
MY524_RS10525	COG0583	DNA-binding transcription factor activity
MY524_RS10575	COG0697	spore germination
MY524_RS10580	COG1279	arginine transmembrane transporter activity
MY524_RS10590	COG0545	Peptidyl-prolyl cis-trans isomerase
MY524_RS10610	COG2703	oxygen carrier activity
MY524_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS10655	COG2111	Na H antiporter
MY524_RS10655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MY524_RS10660	COG1006	Multisubunit Na H antiporter MnhC subunit
MY524_RS10665	COG0651	ATP synthesis coupled electron transport
MY524_RS10670	COG1863	multisubunit Na H antiporter MnhE subunit
MY524_RS10675	COG2212	antiporter activity
MY524_RS10710	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
MY524_RS10730	COG1269	ATP hydrolysis coupled proton transport
MY524_RS10745	COG1230	cation diffusion facilitator family transporter
MY524_RS10775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MY524_RS10850	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MY524_RS10855	COG1178	ABC-type Fe3 transport system permease component
MY524_RS10880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY524_RS10890	COG0745	RESPONSE REGULATOR receiver
MY524_RS10920	COG4636	protein conserved in cyanobacteria
MY524_RS10945	COG1132	(ABC) transporter
MY524_RS10960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MY524_RS10975	COG1752	Esterase of the alpha-beta hydrolase superfamily
MY524_RS10980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MY524_RS11015	COG5002	protein histidine kinase activity
MY524_RS11015	COG2205	protein histidine kinase activity
MY524_RS11015	COG0784	Response regulator, receiver
MY524_RS11095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MY524_RS11100	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MY524_RS11105	COG3454	Phosphonate metabolism
MY524_RS11110	COG4778	phosphonate C-P lyase system protein PhnL
MY524_RS11115	COG4107	phosphonate C-P lyase system protein PhnK
MY524_RS11125	COG3626	phosphonate metabolism
MY524_RS11130	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MY524_RS11135	COG3624	Phosphonate C-P lyase system protein PhnG
MY524_RS11140	COG2188	Transcriptional regulator
MY524_RS11145	COG3639	organic phosphonate transmembrane transporter activity
MY524_RS11150	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MY524_RS11160	COG2095	MarC family integral membrane protein
MY524_RS11175	COG0848	biopolymer transport protein
MY524_RS11180	COG0811	peptide transport
MY524_RS11185	COG0811	peptide transport
MY524_RS11215	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MY524_RS11225	COG3609	addiction module antidote protein, CC2985 family
MY524_RS11290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY524_RS11295	COG1773	rubredoxin
MY524_RS11300	COG1773	rubredoxin
MY524_RS11345	COG3384	dioxygenase
MY524_RS11440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MY524_RS11455	COG0705	Rhomboid family
MY524_RS11480	COG1842	Phage shock protein A
MY524_RS11525	COG1797	cobyrinic acid a,c-diamide synthase activity
MY524_RS11540	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MY524_RS11620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MY524_RS11625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MY524_RS11630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MY524_RS11635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MY524_RS11640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MY524_RS11645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MY524_RS11650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MY524_RS11655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MY524_RS11665	COG0356	it plays a direct role in the translocation of protons across the membrane
MY524_RS11675	COG1475	DNA binding
MY524_RS11680	COG1192	Involved in chromosome partitioning
MY524_RS11685	COG0357	Ribosomal RNA small subunit methyltransferase G
MY524_RS11690	COG0445	tRNA wobble uridine modification
MY524_RS11700	COG0426	domain, Protein
MY524_RS11700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MY524_RS11710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MY524_RS11715	COG0706	membrane insertase activity
MY524_RS11720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MY524_RS11725	COG0594	ribonuclease P activity
MY524_RS11735	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MY524_RS11740	COG0592	DNA-directed DNA polymerase activity
MY524_RS11755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MY524_RS11785	COG1560	Kdo2-lipid A biosynthetic process
MY524_RS11790	COG0751	glycine-tRNA ligase activity
MY524_RS11795	COG0752	glycyl-tRNA synthetase alpha subunit
MY524_RS11830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MY524_RS11835	COG0569	domain protein
MY524_RS11845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MY524_RS11850	COG0242	peptide deformylase activity
MY524_RS11860	COG0758	DNA mediated transformation
MY524_RS11865	COG0009	L-threonylcarbamoyladenylate synthase
MY524_RS11875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MY524_RS11880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MY524_RS11895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MY524_RS11900	COG0339	signal peptide processing
MY524_RS11920	COG0534	Mate efflux family protein
MY524_RS11960	COG1612	heme a metabolic process
MY524_RS11965	COG0109	protoheme IX farnesyltransferase activity
MY524_RS11970	COG3920	Histidine kinase
MY524_RS11985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS12010	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MY524_RS12020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MY524_RS12040	COG0784	Response regulator, receiver
MY524_RS12040	COG2205	protein histidine kinase activity
MY524_RS12050	COG0745	RESPONSE REGULATOR receiver
MY524_RS12115	COG0784	Response regulator, receiver
MY524_RS12115	COG2205	protein histidine kinase activity
MY524_RS12120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MY524_RS12125	COG0602	queuosine metabolic process
MY524_RS12130	COG0243	molybdopterin cofactor binding
MY524_RS12145	COG0583	DNA-binding transcription factor activity
MY524_RS12185	COG2195	Cleaves the N-terminal amino acid of tripeptides
MY524_RS12190	COG3360	Dodecin
MY524_RS12200	COG3550	peptidyl-serine autophosphorylation
MY524_RS12230	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS12255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MY524_RS12260	COG0513	Belongs to the DEAD box helicase family
MY524_RS12270	COG0017	Asparaginyl-tRNA synthetase
MY524_RS12275	COG0392	lysyltransferase activity
MY524_RS12275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MY524_RS12300	COG0545	Peptidyl-prolyl cis-trans isomerase
MY524_RS12330	COG0583	DNA-binding transcription factor activity
MY524_RS12335	COG4608	Belongs to the ABC transporter superfamily
MY524_RS12340	COG0444	Belongs to the ABC transporter superfamily
MY524_RS12345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MY524_RS12350	COG0601	transmembrane transport
MY524_RS12355	COG0747	negative chemotaxis
MY524_RS12370	COG0579	oxidoreductase
MY524_RS12395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MY524_RS12435	COG2354	Protein conserved in bacteria
MY524_RS12440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MY524_RS12450	COG0583	DNA-binding transcription factor activity
MY524_RS12475	COG2832	Protein of unknown function (DUF454)
MY524_RS12485	COG2026	Addiction module toxin, RelE StbE family
MY524_RS12490	COG0840	transmembrane signaling receptor activity
MY524_RS12495	COG1047	Peptidyl-prolyl cis-trans
MY524_RS12515	COG1942	4-Oxalocrotonate Tautomerase
MY524_RS12520	COG3177	Filamentation induced by cAMP protein fic
MY524_RS12525	COG3530	Putative quorum-sensing-regulated virulence factor
MY524_RS12545	COG0545	Peptidyl-prolyl cis-trans isomerase
MY524_RS12550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MY524_RS12565	COG2197	response regulator
MY524_RS12605	COG5002	protein histidine kinase activity
MY524_RS12610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MY524_RS12630	COG1739	Uncharacterized protein family UPF0029
MY524_RS12655	COG3220	belongs to the UPF0276 family
MY524_RS12670	COG1942	4-Oxalocrotonate Tautomerase
MY524_RS12675	COG0477	Major facilitator Superfamily
MY524_RS12680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY524_RS12680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY524_RS12695	COG0745	RESPONSE REGULATOR receiver
MY524_RS12700	COG5002	protein histidine kinase activity
MY524_RS12715	COG3655	Transcriptional regulator
MY524_RS12720	COG0753	catalase activity
MY524_RS12735	COG4251	negative regulation of phosphorylation
MY524_RS12740	COG0784	Response regulator, receiver
MY524_RS12745	COG0730	response to heat
MY524_RS12770	COG4681	YaeQ
MY524_RS12780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY524_RS12795	COG3850	Histidine kinase
MY524_RS12795	COG4999	Histidine kinase
MY524_RS12795	COG2205	protein histidine kinase activity
MY524_RS12795	COG3437	response regulator, receiver
MY524_RS12805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MY524_RS12810	COG4221	oxidoreductase activity
MY524_RS12830	COG0346	lactoylglutathione lyase activity
MY524_RS12890	COG3344	reverse transcriptase
MY524_RS12900	COG0517	IMP dehydrogenase activity
MY524_RS12905	COG4974	Belongs to the 'phage' integrase family
MY524_RS12910	COG0033	Phosphoglucomutase
MY524_RS12920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY524_RS12925	COG3122	Protein conserved in bacteria
MY524_RS12990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY524_RS12995	COG3089	Belongs to the UPF0270 family
MY524_RS13000	COG1250	3-hydroxyacyl-CoA dehydrogenase
MY524_RS13000	COG1024	Enoyl-CoA hydratase
MY524_RS13025	COG2204	response regulator
MY524_RS13035	COG2378	regulation of single-species biofilm formation
MY524_RS13070	COG1671	Belongs to the UPF0178 family
MY524_RS13080	COG1278	Cold shock
MY524_RS13105	COG3123	guanosine phosphorylase activity
MY524_RS13130	COG1278	Cold shock
MY524_RS13140	COG3647	Membrane
MY524_RS13160	COG0596	Alpha beta hydrolase
MY524_RS13175	COG3344	reverse transcriptase
MY524_RS13205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MY524_RS13210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MY524_RS13215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MY524_RS13220	COG2204	response regulator
MY524_RS13225	COG4191	Histidine kinase
MY524_RS13255	COG4115	mRNA cleavage
MY524_RS13260	COG2161	toxin-antitoxin pair type II binding
MY524_RS13275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY524_RS13285	COG1126	abc transporter atp-binding protein
MY524_RS13290	COG0765	amino acid transport
MY524_RS13295	COG4597	amino acid ABC transporter
MY524_RS13300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY524_RS13310	COG3148	PFAM DTW domain containing protein
MY524_RS13335	COG2337	Toxic component of a toxin-antitoxin (TA) module
MY524_RS13340	COG2336	PFAM SpoVT AbrB
MY524_RS13355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MY524_RS13365	COG1960	acyl-CoA dehydrogenase activity
MY524_RS13380	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MY524_RS13395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY524_RS13405	COG1166	arginine decarboxylase activity
MY524_RS13410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MY524_RS13430	COG0004	ammonium transporteR
MY524_RS13435	COG0347	Belongs to the P(II) protein family
MY524_RS13445	COG0606	chelatase, subunit chli
MY524_RS13455	COG1116	anion transmembrane transporter activity
MY524_RS13465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MY524_RS13465	COG1116	anion transmembrane transporter activity
MY524_RS13475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MY524_RS13480	COG0590	tRNA wobble adenosine to inosine editing
MY524_RS13485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MY524_RS13495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MY524_RS13500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MY524_RS13510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MY524_RS13510	COG2813	Specifically methylates the guanine in position
MY524_RS13515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MY524_RS13520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MY524_RS13560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MY524_RS13565	COG0826	peptidase U32
MY524_RS13585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MY524_RS13595	COG1025	Belongs to the peptidase M16 family
MY524_RS13600	COG2771	luxR family
MY524_RS13620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY524_RS13630	COG1538	Outer membrane efflux protein
MY524_RS13640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MY524_RS13645	COG1561	YicC-like family, N-terminal region
MY524_RS13670	COG3550	peptidyl-serine autophosphorylation
MY524_RS13675	COG3620	sequence-specific DNA binding
MY524_RS13680	COG1024	Enoyl-CoA hydratase
MY524_RS13685	COG1902	pentaerythritol trinitrate reductase activity
MY524_RS13685	COG0446	pyridine nucleotide-disulphide oxidoreductase
MY524_RS13690	COG1309	transcriptional regulator
MY524_RS13695	COG3177	Filamentation induced by cAMP protein fic
MY524_RS13710	COG3436	PFAM IS66 Orf2 family protein
MY524_RS13725	COG0494	nUDIX hydrolase
MY524_RS13740	COG5001	Diguanylate cyclase
MY524_RS13740	COG3706	GGDEF domain
MY524_RS13740	COG4251	negative regulation of phosphorylation
MY524_RS13740	COG2203	Gaf domain
MY524_RS13750	COG1758	RNA polymerase activity
MY524_RS13755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MY524_RS13770	COG0583	DNA-binding transcription factor activity
MY524_RS13775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MY524_RS13895	COG1610	YqeY-like protein
MY524_RS13900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MY524_RS13905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MY524_RS13910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MY524_RS13915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MY524_RS13920	COG0302	gtp cyclohydrolase
MY524_RS13920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MY524_RS13925	COG0166	Belongs to the GPI family
MY524_RS13930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MY524_RS13935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MY524_RS13945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MY524_RS13955	COG2204	response regulator
MY524_RS13960	COG4191	Histidine kinase
MY524_RS13965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY524_RS13970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MY524_RS14005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MY524_RS14020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MY524_RS14025	COG0352	thiamine-phosphate diphosphorylase activity
MY524_RS14030	COG0351	phosphomethylpyrimidine kinase
MY524_RS14030	COG0352	thiamine-phosphate diphosphorylase activity
MY524_RS14035	COG1981	membrane
MY524_RS14045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MY524_RS14060	COG0316	Belongs to the HesB IscA family
MY524_RS14070	COG0739	heme binding
MY524_RS14075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MY524_RS14140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MY524_RS14140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MY524_RS14185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MY524_RS14190	COG0081	regulation of translation
MY524_RS14195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MY524_RS14200	COG0222	ribosome binding
MY524_RS14205	COG0085	RNA polymerase activity
MY524_RS14210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MY524_RS14215	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MY524_RS14220	COG0049	tRNA binding
MY524_RS14225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MY524_RS14230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MY524_RS14235	COG0051	transcription antitermination factor activity, RNA binding
MY524_RS14240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MY524_RS14245	COG0088	Forms part of the polypeptide exit tunnel
MY524_RS14250	COG0089	rRNA binding
MY524_RS14255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MY524_RS14260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MY524_RS14265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MY524_RS14270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MY524_RS14275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MY524_RS14280	COG0255	Belongs to the universal ribosomal protein uL29 family
MY524_RS14285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MY524_RS14290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MY524_RS14295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MY524_RS14300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MY524_RS14305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MY524_RS14310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MY524_RS14315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MY524_RS14320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MY524_RS14325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MY524_RS14330	COG1841	ribosomal large subunit assembly
MY524_RS14335	COG0200	Binds to the 23S rRNA
MY524_RS14345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MY524_RS14350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MY524_RS14355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MY524_RS14360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MY524_RS14365	COG0202	RNA polymerase activity
MY524_RS14370	COG0203	ribosomal protein L17
MY524_RS14380	COG2814	Major facilitator Superfamily
MY524_RS14395	COG0527	aspartate kinase activity
MY524_RS14400	COG1917	Cupin 2, conserved barrel domain protein
MY524_RS14410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MY524_RS14420	COG1846	Transcriptional regulator
MY524_RS14450	COG3409	Peptidoglycan-binding domain 1 protein
MY524_RS14450	COG3267	Type II secretory pathway component ExeA
MY524_RS14460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MY524_RS14465	COG1459	type II secretion system
MY524_RS14510	COG2204	response regulator
MY524_RS14515	COG3852	Histidine kinase
MY524_RS14525	COG0174	glutamine synthetase
MY524_RS14530	COG1217	gtp-binding protein TYPA
MY524_RS14540	COG1490	D-aminoacyl-tRNA deacylase activity
MY524_RS14550	COG4116	CYTH
MY524_RS14585	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MY524_RS14605	COG0110	maltose O-acetyltransferase activity
MY524_RS14615	COG1696	Membrane protein involved in D-alanine export
MY524_RS14630	COG1216	Glycosyl transferase, family 2
MY524_RS14630	COG1442	glycosyl transferase family 8
MY524_RS14645	COG0726	polysaccharide deacetylase
MY524_RS14660	COG1519	Transferase
MY524_RS14665	COG1538	Outer membrane efflux protein
MY524_RS14670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MY524_RS14675	COG0494	nUDIX hydrolase
MY524_RS14685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MY524_RS14690	COG3150	esterase
MY524_RS14695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MY524_RS14700	COG0509	glycine decarboxylation via glycine cleavage system
MY524_RS14705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MY524_RS14710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MY524_RS14735	COG0494	nUDIX hydrolase
MY524_RS14740	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MY524_RS14755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MY524_RS14760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MY524_RS14770	COG0018	arginyl-trna synthetase
MY524_RS14775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MY524_RS14780	COG0254	rRNA binding
MY524_RS14790	COG0281	malic enzyme
MY524_RS14795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MY524_RS14800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MY524_RS14805	COG2003	Belongs to the UPF0758 family
MY524_RS14810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MY524_RS14815	COG0756	dUTP diphosphatase activity
MY524_RS14825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MY524_RS14830	COG3706	GGDEF domain
MY524_RS14845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MY524_RS14845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MY524_RS14855	COG5001	Diguanylate cyclase
MY524_RS14855	COG5002	protein histidine kinase activity
MY524_RS14860	COG3954	Phosphoribulokinase
MY524_RS14870	COG1765	OsmC-like protein
MY524_RS14885	COG0288	reversible hydration of carbon dioxide
MY524_RS14900	COG1607	acyl-coa hydrolase
MY524_RS14925	COG0581	inorganic phosphate transmembrane transporter activity
MY524_RS14930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MY524_RS14950	COG0537	adenosine 5'-monophosphoramidase activity
MY524_RS14955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MY524_RS14965	COG0668	transmembrane transport
MY524_RS14970	COG0709	Synthesizes selenophosphate from selenide and ATP
MY524_RS14975	COG3639	organic phosphonate transmembrane transporter activity
MY524_RS14980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MY524_RS14985	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MY524_RS14990	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MY524_RS15005	COG0564	pseudouridine synthase activity
MY524_RS15040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS15045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS15050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS15055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS15075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MY524_RS15080	COG3161	chorismate lyase activity
MY524_RS15110	COG1946	Acyl-CoA thioesterase
MY524_RS15135	COG0306	phosphate transporter
MY524_RS15140	COG3706	GGDEF domain
MY524_RS15140	COG4251	negative regulation of phosphorylation
MY524_RS15140	COG5001	Diguanylate cyclase
MY524_RS15140	COG2203	Gaf domain
MY524_RS15155	COG0076	glutamate decarboxylase activity
MY524_RS15190	COG1960	acyl-CoA dehydrogenase activity
MY524_RS15200	COG1309	transcriptional regulator
MY524_RS15210	COG1444	tRNA N-acetyltransferase activity
MY524_RS15255	COG0628	permease
MY524_RS15275	COG0405	Gamma-glutamyltransferase
MY524_RS15280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MY524_RS15285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MY524_RS15300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MY524_RS15360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MY524_RS15365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MY524_RS15375	COG0070	glutamate synthase
MY524_RS15375	COG0069	glutamate synthase activity
MY524_RS15375	COG0067	glutamate synthase
MY524_RS15380	COG0493	'glutamate synthase
MY524_RS15385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MY524_RS15400	COG3344	reverse transcriptase
MY524_RS15420	COG0488	(ABC) transporter
MY524_RS15425	COG1742	UPF0060 membrane protein
MY524_RS15435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY524_RS15445	COG0640	Transcriptional regulator
MY524_RS15450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MY524_RS15455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MY524_RS15460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY524_RS15460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY524_RS15475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MY524_RS15480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MY524_RS15490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MY524_RS15500	COG1355	regulation of microtubule-based process
MY524_RS15505	COG2078	PFAM AMMECR1 domain protein
MY524_RS15505	COG3885	ferrous iron binding
MY524_RS15515	COG0142	geranyltranstransferase activity
MY524_RS15520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MY524_RS15530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MY524_RS15535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MY524_RS15540	COG0268	Binds directly to 16S ribosomal RNA
MY524_RS15545	COG0728	peptidoglycan biosynthetic process
MY524_RS15550	COG0196	riboflavin kinase activity
MY524_RS15555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MY524_RS15565	COG1047	Peptidyl-prolyl cis-trans
MY524_RS15570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MY524_RS15610	COG4969	Belongs to the N-Me-Phe pilin family
MY524_RS15615	COG4968	Prepilin-type N-terminal cleavage methylation domain
MY524_RS15635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MY524_RS15635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY524_RS15670	COG0028	Belongs to the TPP enzyme family
MY524_RS15685	COG1183	phosphatidylcholine synthase activity
MY524_RS15695	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MY524_RS15720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MY524_RS15730	COG0456	acetyltransferase
MY524_RS15735	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MY524_RS15740	COG4191	Histidine kinase
MY524_RS15745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MY524_RS15750	COG0084	hydrolase, TatD family'
MY524_RS15755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MY524_RS15760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MY524_RS15765	COG0723	plastoquinol--plastocyanin reductase activity
MY524_RS15770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MY524_RS15775	COG2857	Cytochrome c1
MY524_RS15780	COG0625	glutathione transferase activity
MY524_RS15785	COG2969	positive regulation of protein catabolic process
MY524_RS15790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MY524_RS15795	COG0792	nuclease activity
MY524_RS15800	COG3107	peptidoglycan biosynthetic process
MY524_RS15805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MY524_RS15815	COG2001	Belongs to the MraZ family
MY524_RS15820	COG0275	rRNA processing
MY524_RS15835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MY524_RS15840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MY524_RS15845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY524_RS15850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MY524_RS15855	COG0772	Belongs to the SEDS family
MY524_RS15860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MY524_RS15865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MY524_RS15870	COG1181	Belongs to the D-alanine--D-alanine ligase family
MY524_RS15875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MY524_RS15890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MY524_RS15900	COG0739	heme binding
MY524_RS15905	COG0653	protein targeting
MY524_RS15910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MY524_RS15915	COG0352	thiamine-phosphate diphosphorylase activity
MY524_RS15920	COG0315	cyclic pyranopterin monophosphate synthase activity
MY524_RS15925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MY524_RS15930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MY524_RS15935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MY524_RS15940	COG0142	geranyltranstransferase activity
MY524_RS15950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MY524_RS15970	COG0730	response to heat
MY524_RS15975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MY524_RS15980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MY524_RS15985	COG0840	transmembrane signaling receptor activity
MY524_RS15985	COG0840	transmembrane signaling receptor activity
MY524_RS15990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MY524_RS15995	COG0129	dihydroxy-acid dehydratase activity
MY524_RS16005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MY524_RS16020	COG0586	Pfam SNARE associated Golgi protein
MY524_RS16025	COG3706	GGDEF domain
MY524_RS16035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MY524_RS16040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MY524_RS16050	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MY524_RS16055	COG0768	penicillin binding
MY524_RS16060	COG0772	Belongs to the SEDS family
MY524_RS16065	COG2951	lytic endotransglycosylase activity
MY524_RS16070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MY524_RS16075	COG1686	Belongs to the peptidase S11 family
MY524_RS16085	COG2921	Belongs to the UPF0250 family
MY524_RS16110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MY524_RS16120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MY524_RS16150	COG0217	transcriptional regulatory protein
MY524_RS16155	COG1187	pseudouridine synthase activity
MY524_RS16195	COG0346	lactoylglutathione lyase activity
MY524_RS16200	COG0243	molybdopterin cofactor binding
MY524_RS16210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY524_RS16215	COG2223	nitrite transmembrane transporter activity
MY524_RS16220	COG2223	nitrite transmembrane transporter activity
MY524_RS16225	COG0515	serine threonine protein kinase
MY524_RS16225	COG2815	serine threonine protein kinase
MY524_RS16230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MY524_RS16295	COG4372	Transposase
MY524_RS16335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MY524_RS16340	COG0583	DNA-binding transcription factor activity
MY524_RS16345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MY524_RS16380	COG0427	acetyl-CoA hydrolase
MY524_RS16385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MY524_RS16400	COG0577	efflux transmembrane transporter activity
MY524_RS16400	COG1136	(ABC) transporter
MY524_RS16415	COG4753	response regulator
MY524_RS16415	COG2207	Transcriptional regulator
MY524_RS16440	COG0243	molybdopterin cofactor binding
MY524_RS16445	COG0437	4 iron, 4 sulfur cluster binding
MY524_RS16460	COG3609	addiction module antidote protein, CC2985 family
MY524_RS16480	COG0523	cobalamin synthesis protein
MY524_RS16525	COG0028	Belongs to the TPP enzyme family
MY524_RS16550	COG4978	Transcriptional regulator
MY524_RS16550	COG0789	Transcriptional regulator
MY524_RS16555	COG0500	methyltransferase
MY524_RS16600	COG1309	transcriptional regulator
MY524_RS16605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MY524_RS16620	COG0583	DNA-binding transcription factor activity
MY524_RS16635	COG0205	6-phosphofructokinase activity
MY524_RS16660	COG2166	iron-sulfur cluster assembly
MY524_RS16675	COG0316	Belongs to the HesB IscA family
MY524_RS16685	COG0719	Fe-S assembly protein
MY524_RS16690	COG0396	ATPase activity
MY524_RS16695	COG0719	Fe-S assembly protein
MY524_RS16715	COG2719	SpoVR family
MY524_RS16720	COG2718	Belongs to the UPF0229 family
MY524_RS16725	COG2766	serine protein kinase
MY524_RS16730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MY524_RS16735	COG0432	Pfam Uncharacterised protein family UPF0047
MY524_RS16740	COG0784	Response regulator, receiver
MY524_RS16740	COG2205	protein histidine kinase activity
MY524_RS16740	COG5002	protein histidine kinase activity
MY524_RS16755	COG4399	Belongs to the UPF0754 family
MY524_RS16765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY524_RS16770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MY524_RS16775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MY524_RS16780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MY524_RS16785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MY524_RS16795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MY524_RS16800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY524_RS16805	COG0126	phosphoglycerate kinase activity
MY524_RS16810	COG0191	fructose-bisphosphate aldolase activity
MY524_RS16820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MY524_RS16830	COG0513	Belongs to the DEAD box helicase family
MY524_RS16860	COG2885	chlorophyll binding
MY524_RS16865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY524_RS16870	COG0277	FAD linked oxidase domain protein
MY524_RS16875	COG0179	Fumarylacetoacetate (FAA) hydrolase
MY524_RS16890	COG1187	pseudouridine synthase activity
MY524_RS16895	COG1285	pathogenesis
MY524_RS16925	COG0189	ligase activity
MY524_RS16935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MY524_RS16935	COG3264	Mechanosensitive ion channel
MY524_RS16940	COG0598	Magnesium transport protein CorA
MY524_RS16950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MY524_RS16955	COG2252	PERMEase
MY524_RS16970	COG0189	ligase activity
MY524_RS16970	COG4067	protein conserved in archaea
MY524_RS16980	COG0189	ligase activity
MY524_RS16990	COG0583	DNA-binding transcription factor activity
MY524_RS17020	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS17030	COG1024	Enoyl-CoA hydratase
MY524_RS17040	COG1960	acyl-CoA dehydrogenase activity
MY524_RS17045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY524_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS17060	COG1309	transcriptional regulator
MY524_RS17120	COG1401	restriction endodeoxyribonuclease activity
MY524_RS17125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MY524_RS17135	COG0732	type I restriction modification DNA specificity domain
MY524_RS17140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MY524_RS17160	COG3609	addiction module antidote protein, CC2985 family
MY524_RS17200	COG0439	Biotin carboxylase
MY524_RS17220	COG1132	(ABC) transporter
MY524_RS17275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MY524_RS17310	COG0419	ATPase involved in DNA repair
MY524_RS17315	COG0420	3'-5' exonuclease activity
MY524_RS17320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MY524_RS17330	COG1012	belongs to the aldehyde dehydrogenase family
MY524_RS17350	COG4175	Glycine betaine
MY524_RS17365	COG0493	'glutamate synthase
MY524_RS17375	COG1061	Type III restriction enzyme res subunit
MY524_RS17380	COG0204	Acyl-transferase
MY524_RS17385	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MY524_RS17405	COG0513	Belongs to the DEAD box helicase family
MY524_RS17410	COG1187	pseudouridine synthase activity
MY524_RS17490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY524_RS17500	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MY524_RS17505	COG0347	Belongs to the P(II) protein family
MY524_RS17515	COG0789	Transcriptional regulator
MY524_RS17520	COG2217	Heavy metal translocating P-type atpase
MY524_RS17555	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MY524_RS17570	COG1136	(ABC) transporter
MY524_RS17575	COG0577	efflux transmembrane transporter activity
MY524_RS17590	COG2132	Multicopper oxidase
MY524_RS17640	COG1231	oxidoreductase activity
MY524_RS17645	COG0484	heat shock protein binding
MY524_RS17650	COG0789	Transcriptional regulator
MY524_RS17655	COG1280	lysine exporter protein (LysE YggA)
MY524_RS17665	COG0791	NLP P60 protein
MY524_RS17705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MY524_RS17785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MY524_RS17800	COG0840	transmembrane signaling receptor activity
MY524_RS17815	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MY524_RS17835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MY524_RS17840	COG0488	(ABC) transporter
MY524_RS17875	COG0417	DNA replication proofreading
MY524_RS17885	COG3228	Belongs to the MtfA family
MY524_RS17900	COG2205	protein histidine kinase activity
MY524_RS17900	COG3437	response regulator, receiver
MY524_RS17900	COG3850	Histidine kinase
MY524_RS17900	COG4999	Histidine kinase
MY524_RS17935	COG2816	NAD+ diphosphatase activity
MY524_RS17940	COG3588	fructose-bisphosphate aldolase
MY524_RS17945	COG1022	Amp-dependent synthetase and ligase
MY524_RS17950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MY524_RS17955	COG3091	SprT-like family
MY524_RS17975	COG2199	diguanylate cyclase activity
MY524_RS17975	COG2200	EAL domain
MY524_RS17980	COG3038	cytochrome b561
MY524_RS17985	COG2353	YceI-like domain
MY524_RS18025	COG0745	RESPONSE REGULATOR receiver
MY524_RS18030	COG2205	protein histidine kinase activity
MY524_RS18045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MY524_RS18050	COG3842	ATPase activity
MY524_RS18055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MY524_RS18060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY524_RS18070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MY524_RS18085	COG4536	flavin adenine dinucleotide binding
MY524_RS18090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MY524_RS18095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MY524_RS18100	COG0228	four-way junction DNA binding
MY524_RS18105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MY524_RS18115	COG0335	large ribosomal subunit rRNA binding
MY524_RS18120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MY524_RS18125	COG0436	Aminotransferase
MY524_RS18140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MY524_RS18145	COG0824	Thioesterase
MY524_RS18155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MY524_RS18160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MY524_RS18165	COG1639	'signal transduction protein
MY524_RS18215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MY524_RS18235	COG0481	GTPase activity
MY524_RS18240	COG0681	Belongs to the peptidase S26 family
MY524_RS18250	COG0571	ribonuclease III activity
MY524_RS18260	COG1381	Involved in DNA repair and RecF pathway recombination
MY524_RS18265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MY524_RS18270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY524_RS18275	COG0154	amidase activity
MY524_RS18280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY524_RS18285	COG1077	Cell shape determining protein MreB Mrl
MY524_RS18290	COG1792	Involved in formation and maintenance of cell shape
MY524_RS18295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MY524_RS18300	COG0424	maF-like protein
MY524_RS18305	COG1530	ribonuclease E activity
MY524_RS18315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY524_RS18320	COG3028	Belongs to the UPF0307 family
MY524_RS18325	COG2239	Acts as a magnesium transporter
MY524_RS18330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MY524_RS18335	COG1660	Displays ATPase and GTPase activities
MY524_RS18355	COG1137	ATPase activity
MY524_RS18380	COG1127	ABC transporter
MY524_RS18385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MY524_RS18390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MY524_RS18405	COG5007	Belongs to the BolA IbaG family
MY524_RS18410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MY524_RS18415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MY524_RS18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MY524_RS18435	COG3105	Protein conserved in bacteria
MY524_RS18440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MY524_RS18450	COG0183	Belongs to the thiolase family
MY524_RS18465	COG2197	response regulator
MY524_RS18500	COG0640	Transcriptional regulator
MY524_RS18510	COG0784	Response regulator, receiver
MY524_RS18510	COG2205	protein histidine kinase activity
MY524_RS18510	COG5002	protein histidine kinase activity
MY524_RS18525	COG1720	tRNA m6t6A37 methyltransferase activity
MY524_RS18530	COG1346	cytolysis
MY524_RS18535	COG1380	Effector of murein hydrolase LrgA
MY524_RS18545	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MY524_RS18550	COG0237	dephospho-CoA kinase activity
MY524_RS18585	COG0463	Glycosyl transferase, family 2
MY524_RS18590	COG0438	transferase activity, transferring glycosyl groups
MY524_RS18595	COG0367	asparagine synthase
MY524_RS18605	COG2089	acid synthase
MY524_RS18610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MY524_RS18620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY524_RS18655	COG2226	methyltransferase
MY524_RS18675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MY524_RS18680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MY524_RS18690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MY524_RS18710	COG1088	dTDP-glucose 4,6-dehydratase activity
MY524_RS18725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MY524_RS18750	COG0529	Catalyzes the synthesis of activated sulfate
MY524_RS18755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MY524_RS18775	COG2165	general secretion pathway protein
MY524_RS18805	COG1450	Type ii and iii secretion system protein
MY524_RS18815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MY524_RS18845	COG0438	transferase activity, transferring glycosyl groups
MY524_RS18845	COG1216	Glycosyl transferase, family 2
MY524_RS18890	COG1086	Polysaccharide biosynthesis protein
MY524_RS18915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MY524_RS18925	COG0662	Cupin 2, conserved barrel domain protein
MY524_RS18925	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MY524_RS18935	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
MY524_RS18980	COG2900	Belongs to the SlyX family
MY524_RS19000	COG2226	methyltransferase
MY524_RS19005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MY524_RS19010	COG2171	N-acyltransferase activity
MY524_RS19015	COG1393	Belongs to the ArsC family
MY524_RS19020	COG0436	Aminotransferase
MY524_RS19025	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MY524_RS19030	COG0024	Methionine aminopeptidase
MY524_RS19035	COG0052	Belongs to the universal ribosomal protein uS2 family
MY524_RS19040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MY524_RS19045	COG0528	UMP kinase activity
MY524_RS19050	COG0233	cytoplasmic translational termination
MY524_RS19065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MY524_RS19075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MY524_RS19085	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY524_RS19090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MY524_RS19095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY524_RS19100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY524_RS19115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MY524_RS19120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MY524_RS19125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MY524_RS19140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MY524_RS19150	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MY524_RS19155	COG0439	Biotin carboxylase
MY524_RS19160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY524_RS19175	COG3154	lipid carrier protein
MY524_RS19180	COG1242	4 iron, 4 sulfur cluster binding
MY524_RS19185	COG0826	peptidase U32
MY524_RS19190	COG0826	peptidase U32
MY524_RS19205	COG1203	CRISPR-associated helicase, Cas3
MY524_RS19240	COG1518	maintenance of DNA repeat elements
MY524_RS19245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MY524_RS19260	COG1067	ATP-dependent peptidase activity
MY524_RS19280	COG4566	intracellular signal transduction
MY524_RS19285	COG4191	Histidine kinase
MY524_RS19295	COG2962	Rard protein
MY524_RS19300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MY524_RS19330	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MY524_RS19335	COG0372	Belongs to the citrate synthase family
MY524_RS19340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MY524_RS19355	COG3153	acetyltransferase
MY524_RS19355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY524_RS19360	COG2133	pyrroloquinoline quinone binding
MY524_RS19370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MY524_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS19420	COG4771	TonB-dependent receptor
MY524_RS19425	COG0222	ribosome binding
MY524_RS19435	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY524_RS19435	COG0596	Alpha beta hydrolase
MY524_RS19440	COG1309	transcriptional regulator
MY524_RS19450	COG2738	Putative neutral zinc metallopeptidase
MY524_RS19500	COG2161	toxin-antitoxin pair type II binding
MY524_RS19505	COG4115	mRNA cleavage
MY524_RS19585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MY524_RS19595	COG0563	adenylate kinase activity
MY524_RS19600	COG1214	PFAM Peptidase M22, glycoprotease
MY524_RS19605	COG1968	undecaprenyl-diphosphatase activity
MY524_RS19615	COG0742	ribosomal rna small subunit methyltransferase
MY524_RS19620	COG2937	Belongs to the GPAT DAPAT family
MY524_RS19625	COG1131	(ABC) transporter
MY524_RS19640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MY524_RS19665	COG4191	Histidine kinase
MY524_RS19690	COG1120	ATPase activity
MY524_RS19695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MY524_RS19700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MY524_RS19705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MY524_RS19730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MY524_RS19745	COG0583	DNA-binding transcription factor activity
MY524_RS19750	COG1960	acyl-CoA dehydrogenase activity
MY524_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS19770	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS19780	COG2199	diguanylate cyclase activity
MY524_RS19780	COG2200	EAL domain
MY524_RS19785	COG1785	Belongs to the alkaline phosphatase family
MY524_RS19800	COG1573	uracil-dna glycosylase
MY524_RS19810	COG1785	Belongs to the alkaline phosphatase family
MY524_RS19830	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MY524_RS19835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY524_RS19865	COG0204	Acyl-transferase
MY524_RS19890	COG2259	Doxx family
MY524_RS19910	COG0469	pyruvate kinase activity
MY524_RS19915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY524_RS19920	COG2996	Protein conserved in bacteria
MY524_RS19935	COG0668	transmembrane transport
MY524_RS19940	COG1643	Atp-dependent helicase
MY524_RS19950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MY524_RS19955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MY524_RS19975	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MY524_RS19995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MY524_RS20035	COG1940	carbohydrate kinase activity
MY524_RS20050	COG0525	valine-tRNA ligase activity
MY524_RS20065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MY524_RS20070	COG0795	lipopolysaccharide-transporting ATPase activity
MY524_RS20075	COG0795	lipopolysaccharide-transporting ATPase activity
MY524_RS20095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MY524_RS20105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MY524_RS20125	COG3630	sodium ion export across plasma membrane
MY524_RS20130	COG0511	ligase activity, forming carbon-carbon bonds
MY524_RS20130	COG5016	pyruvate
MY524_RS20135	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MY524_RS20165	COG1677	Flagellar hook-basal body complex protein FliE
MY524_RS20200	COG0745	RESPONSE REGULATOR receiver
MY524_RS20205	COG0643	Histidine kinase
MY524_RS20205	COG2198	Histidine kinase
MY524_RS20210	COG0835	chemotaxis
MY524_RS20220	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MY524_RS20225	COG2201	protein-glutamate methylesterase activity
MY524_RS20265	COG3190	flagellar
MY524_RS20275	COG1987	bacterial-type flagellum assembly
MY524_RS20315	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MY524_RS20320	COG2198	Histidine kinase
MY524_RS20320	COG0784	Response regulator, receiver
MY524_RS20320	COG0643	Histidine kinase
MY524_RS20325	COG2201	protein-glutamate methylesterase activity
MY524_RS20330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MY524_RS20340	COG1192	Involved in chromosome partitioning
MY524_RS20355	COG0835	chemotaxis
MY524_RS20365	COG2257	FlhB HrpN YscU SpaS Family
MY524_RS20375	COG4133	protoheme IX ABC transporter activity
MY524_RS20395	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MY524_RS20400	COG1138	Cytochrome C-type biogenesis protein
MY524_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS20425	COG0546	phosphoglycolate phosphatase activity
MY524_RS20430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY524_RS20435	COG0402	S-adenosylhomocysteine deaminase activity
MY524_RS20440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MY524_RS20460	COG1024	Enoyl-CoA hydratase
MY524_RS20460	COG1250	3-hydroxyacyl-CoA dehydrogenase
MY524_RS20465	COG0183	Belongs to the thiolase family
MY524_RS20485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MY524_RS20490	COG0047	phosphoribosylformylglycinamidine synthase activity
MY524_RS20490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MY524_RS20510	COG3313	Fe-S protein
MY524_RS20515	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MY524_RS20550	COG2925	Exonuclease
MY524_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
MY524_RS20580	COG0631	protein serine/threonine phosphatase activity
MY524_RS20605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY524_RS20620	COG2204	response regulator
MY524_RS20635	COG0778	Nitroreductase
MY524_RS20640	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MY524_RS20645	COG0653	protein targeting
MY524_RS20650	COG0515	serine threonine protein kinase
MY524_RS20665	COG0450	alkyl hydroperoxide reductase
MY524_RS20670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MY524_RS20675	COG0418	dihydroorotase activity
MY524_RS20685	COG0137	argininosuccinate synthase activity
MY524_RS20695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MY524_RS20705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MY524_RS20705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MY524_RS20720	COG2154	pterin-4-alpha-carbinolamine dehydratase
MY524_RS20725	COG0788	formyltetrahydrofolate deformylase activity
MY524_RS20740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MY524_RS20745	COG1605	Chorismate mutase
MY524_RS20745	COG0077	Prephenate dehydratase
MY524_RS20750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MY524_RS20755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MY524_RS20760	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MY524_RS20770	COG0776	regulation of translation
MY524_RS20780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MY524_RS20785	COG0284	orotidine-5'-phosphate decarboxylase activity
MY524_RS20795	COG0436	Aminotransferase
MY524_RS20800	COG0556	nucleotide-excision repair
MY524_RS20805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MY524_RS20815	COG0167	dihydroorotate dehydrogenase activity
MY524_RS20820	COG3130	regulation of translation
MY524_RS20825	COG0116	Belongs to the methyltransferase superfamily
MY524_RS20825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MY524_RS20850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MY524_RS20855	COG1362	aminopeptidase activity
MY524_RS20875	COG0429	hydrolase of the alpha beta-hydrolase fold
MY524_RS20885	COG4181	ATPase activity
MY524_RS20890	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MY524_RS20920	COG1024	Enoyl-CoA hydratase
MY524_RS20945	COG4974	Belongs to the 'phage' integrase family
MY524_RS20950	COG0517	IMP dehydrogenase activity
MY524_RS20965	COG3344	reverse transcriptase
MY524_RS21005	COG3547	Transposase (IS116 IS110 IS902 family)
MY524_RS21045	COG0326	Molecular chaperone. Has ATPase activity
MY524_RS21075	COG3177	Filamentation induced by cAMP protein fic
MY524_RS21080	COG2837	iron assimilation
MY524_RS21085	COG3706	GGDEF domain
MY524_RS21090	COG2201	protein-glutamate methylesterase activity
MY524_RS21125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MY524_RS21140	COG0023	Translation Initiation Factor
MY524_RS21145	COG5265	(ABC) transporter
MY524_RS21150	COG2824	Alkylphosphonate utilization operon protein PhnA
MY524_RS21155	COG1360	Flagellar Motor Protein
MY524_RS21165	COG2226	methyltransferase
MY524_RS21170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY524_RS21180	COG2814	Major facilitator Superfamily
MY524_RS21185	COG3012	SEC-C Motif Domain Protein
MY524_RS21190	COG0778	Nitroreductase
MY524_RS21195	COG0596	Alpha beta hydrolase
MY524_RS21200	COG2081	HI0933 family
MY524_RS21235	COG3106	COG3106 Predicted ATPase
MY524_RS21240	COG3768	UPF0283 membrane protein
MY524_RS21260	COG0789	Transcriptional regulator
MY524_RS21270	COG0189	ligase activity
MY524_RS21270	COG4067	protein conserved in archaea
MY524_RS21280	COG0189	ligase activity
MY524_RS21300	COG1278	Cold shock
MY524_RS21350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MY524_RS21355	COG0564	pseudouridine synthase activity
MY524_RS21360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY524_RS21365	COG0564	pseudouridine synthase activity
MY524_RS21385	COG2813	Specifically methylates the guanine in position
MY524_RS21395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY524_RS21400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MY524_RS21405	COG1607	acyl-coa hydrolase
MY524_RS21410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY524_RS21445	COG0829	nickel cation binding
MY524_RS21450	COG0831	urea catabolic process
MY524_RS21455	COG0832	Belongs to the urease beta subunit family
MY524_RS21460	COG0804	urea catabolic process
MY524_RS21470	COG0830	nickel cation binding
MY524_RS21475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MY524_RS21495	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MY524_RS21500	COG2813	Specifically methylates the guanine in position
MY524_RS21505	COG0307	riboflavin synthase, alpha
MY524_RS21515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MY524_RS21515	COG0617	tRNA 3'-terminal CCA addition
MY524_RS21515	COG0517	IMP dehydrogenase activity
MY524_RS21525	COG0004	ammonium transporteR
MY524_RS21540	COG1472	Belongs to the glycosyl hydrolase 3 family
MY524_RS21545	COG0668	transmembrane transport
MY524_RS21550	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MY524_RS21565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MY524_RS21575	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY524_RS21580	COG1805	sodium ion transport
MY524_RS21595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY524_RS21600	COG2871	sodium ion transport
MY524_RS21605	COG1477	protein flavinylation
MY524_RS21610	COG2991	Protein conserved in bacteria
MY524_RS21615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY524_RS21620	COG0584	glycerophosphoryl diester phosphodiesterase
MY524_RS21630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MY524_RS21635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MY524_RS21650	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MY524_RS21655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY524_RS21660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY524_RS21695	COG0574	Belongs to the PEP-utilizing enzyme family
MY524_RS21695	COG3848	Pyruvate phosphate dikinase
MY524_RS21705	COG0318	PFAM AMP-dependent synthetase and ligase
MY524_RS21740	COG1803	Methylglyoxal synthase