locus-tag	class	description
CDL62_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDL62_RS00015	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDL62_RS00025	COG0251	oxidation-reduction process
CDL62_RS00030	COG0359	binds to the 23S rRNA
CDL62_RS00035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDL62_RS00040	COG0360	Binds together with S18 to 16S ribosomal RNA
CDL62_RS00045	COG0167	dihydroorotate dehydrogenase activity
CDL62_RS00050	COG0493	'glutamate synthase
CDL62_RS00055	COG0543	2 iron, 2 sulfur cluster binding
CDL62_RS00075	COG3250	beta-galactosidase activity
CDL62_RS00080	COG1609	Transcriptional regulator
CDL62_RS00090	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS00095	COG3661	Belongs to the glycosyl hydrolase 67 family
CDL62_RS00100	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS00105	COG2205	protein histidine kinase activity
CDL62_RS00105	COG3292	Two component regulator propeller
CDL62_RS00105	COG0745	RESPONSE REGULATOR receiver
CDL62_RS00115	COG0668	transmembrane transport
CDL62_RS00135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDL62_RS00140	COG1024	Enoyl-CoA hydratase
CDL62_RS00145	COG0439	Biotin carboxylase
CDL62_RS00155	COG1960	acyl-CoA dehydrogenase activity
CDL62_RS00160	COG3022	response to hydroperoxide
CDL62_RS00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDL62_RS00185	COG3385	transposase activity
CDL62_RS00225	COG4667	esterase of the alpha-beta hydrolase superfamily
CDL62_RS00250	COG3279	Response regulator of the LytR AlgR family
CDL62_RS00255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDL62_RS00260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDL62_RS00265	COG0113	porphobilinogen synthase activity
CDL62_RS00275	COG0181	hydroxymethylbilane synthase activity
CDL62_RS00280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDL62_RS00300	COG0673	inositol 2-dehydrogenase activity
CDL62_RS00310	COG2207	Transcriptional regulator
CDL62_RS00335	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CDL62_RS00340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDL62_RS00370	COG1304	FMN binding
CDL62_RS00375	COG1132	(ABC) transporter
CDL62_RS00380	COG1132	(ABC) transporter
CDL62_RS00385	COG3572	ergothioneine biosynthetic process
CDL62_RS00400	COG0477	Major facilitator Superfamily
CDL62_RS00400	COG2814	Major facilitator Superfamily
CDL62_RS00405	COG2115	Belongs to the xylose isomerase family
CDL62_RS00415	COG2188	Transcriptional regulator
CDL62_RS00425	COG2860	membrane
CDL62_RS00445	COG2356	endonuclease I
CDL62_RS00450	COG1748	Saccharopine dehydrogenase
CDL62_RS00465	COG0514	ATP-dependent DNA helicase (RecQ)
CDL62_RS00480	COG4770	biotin carboxylase activity
CDL62_RS00495	COG3940	Belongs to the glycosyl hydrolase 43 family
CDL62_RS00500	COG2211	Major facilitator Superfamily
CDL62_RS00540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDL62_RS00545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDL62_RS00550	COG0194	GDP metabolic process
CDL62_RS00555	COG1561	YicC-like family, N-terminal region
CDL62_RS00565	COG0534	Mate efflux family protein
CDL62_RS00575	COG4771	TonB-dependent receptor
CDL62_RS00580	COG0702	epimerase
CDL62_RS00600	COG0587	DNA-directed DNA polymerase activity
CDL62_RS00610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDL62_RS00625	COG0778	Nitroreductase
CDL62_RS00640	COG1272	protein, Hemolysin III
CDL62_RS00655	COG4733	cellulase activity
CDL62_RS00660	COG2197	response regulator
CDL62_RS00670	COG3250	beta-galactosidase activity
CDL62_RS00680	COG0330	HflC and HflK could
CDL62_RS00685	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDL62_RS00690	COG3387	PFAM Glycoside hydrolase 15-related
CDL62_RS00725	COG4771	TonB-dependent receptor
CDL62_RS00735	COG0864	Transcriptional regulator
CDL62_RS00745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDL62_RS00750	COG1120	ATPase activity
CDL62_RS00785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDL62_RS00790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDL62_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS00800	COG1956	GAF domain-containing protein
CDL62_RS00810	COG2873	o-acetylhomoserine
CDL62_RS00815	COG2326	polyphosphate kinase activity
CDL62_RS00830	COG1115	amino acid carrier protein
CDL62_RS00840	COG0531	amino acid
CDL62_RS00845	COG2202	Pas domain
CDL62_RS00845	COG2205	protein histidine kinase activity
CDL62_RS00850	COG2183	response to ionizing radiation
CDL62_RS00865	COG0513	Belongs to the DEAD box helicase family
CDL62_RS00870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDL62_RS00885	COG0514	ATP-dependent DNA helicase (RecQ)
CDL62_RS00895	COG0656	L-ascorbic acid biosynthetic process
CDL62_RS00905	COG1846	Transcriptional regulator
CDL62_RS00910	COG0386	Belongs to the glutathione peroxidase family
CDL62_RS00920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDL62_RS00920	COG4651	solute:proton antiporter activity
CDL62_RS00925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDL62_RS00940	COG1187	pseudouridine synthase activity
CDL62_RS00960	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CDL62_RS00975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CDL62_RS00980	COG4206	TonB-dependent receptor
CDL62_RS00980	COG1629	transport
CDL62_RS00985	COG3250	beta-galactosidase activity
CDL62_RS00990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CDL62_RS00995	COG2205	protein histidine kinase activity
CDL62_RS00995	COG0745	RESPONSE REGULATOR receiver
CDL62_RS00995	COG0745	RESPONSE REGULATOR receiver
CDL62_RS00995	COG3292	Two component regulator propeller
CDL62_RS00995	COG3292	Two component regulator propeller
CDL62_RS00995	COG2205	protein histidine kinase activity
CDL62_RS01000	COG4657	Part of a membrane complex involved in electron transport
CDL62_RS01005	COG4660	Part of a membrane complex involved in electron transport
CDL62_RS01015	COG4658	electron transport chain
CDL62_RS01020	COG4656	Part of a membrane complex involved in electron transport
CDL62_RS01035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDL62_RS01045	COG1136	(ABC) transporter
CDL62_RS01045	COG0577	efflux transmembrane transporter activity
CDL62_RS01050	COG2096	Adenosyltransferase
CDL62_RS01075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDL62_RS01080	COG0516	GMP reductase activity
CDL62_RS01080	COG0517	IMP dehydrogenase activity
CDL62_RS01115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDL62_RS01130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDL62_RS01135	COG0534	Mate efflux family protein
CDL62_RS01140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDL62_RS01140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CDL62_RS01145	COG0545	Peptidyl-prolyl cis-trans isomerase
CDL62_RS01150	COG0545	Peptidyl-prolyl cis-trans isomerase
CDL62_RS01155	COG3012	SEC-C Motif Domain Protein
CDL62_RS01175	COG3015	lipoprotein NlpE involved in copper resistance
CDL62_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS01195	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDL62_RS01205	COG1609	Transcriptional regulator
CDL62_RS01210	COG1904	glucuronate isomerase
CDL62_RS01220	COG0800	Aldolase
CDL62_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS01230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDL62_RS01240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDL62_RS01245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDL62_RS01295	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS01310	COG1032	radical SAM domain protein
CDL62_RS01325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDL62_RS01365	COG3420	alginic acid biosynthetic process
CDL62_RS01385	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDL62_RS01395	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDL62_RS01445	COG0450	alkyl hydroperoxide reductase
CDL62_RS01450	COG1342	Belongs to the UPF0251 family
CDL62_RS01490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CDL62_RS01505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDL62_RS01510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDL62_RS01515	COG0363	glucosamine-6-phosphate deaminase activity
CDL62_RS01535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDL62_RS01545	COG0482	sulfurtransferase activity
CDL62_RS01550	COG0592	DNA-directed DNA polymerase activity
CDL62_RS01560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDL62_RS01570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDL62_RS01700	COG1566	PFAM secretion protein HlyD family protein
CDL62_RS01710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDL62_RS01720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDL62_RS01730	COG0681	Belongs to the peptidase S26 family
CDL62_RS01735	COG3385	transposase activity
CDL62_RS01785	COG3590	peptidase
CDL62_RS01825	COG1741	Belongs to the pirin family
CDL62_RS01830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDL62_RS01835	COG0408	coproporphyrinogen oxidase activity
CDL62_RS01845	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDL62_RS01850	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS01860	COG0513	Belongs to the DEAD box helicase family
CDL62_RS01870	COG3250	beta-galactosidase activity
CDL62_RS01885	COG1166	arginine decarboxylase activity
CDL62_RS01900	COG0460	homoserine dehydrogenase
CDL62_RS01900	COG0527	aspartate kinase activity
CDL62_RS01930	COG0673	inositol 2-dehydrogenase activity
CDL62_RS01935	COG1477	protein flavinylation
CDL62_RS01950	COG0673	inositol 2-dehydrogenase activity
CDL62_RS01955	COG3292	Two component regulator propeller
CDL62_RS01955	COG2205	protein histidine kinase activity
CDL62_RS01955	COG3292	Two component regulator propeller
CDL62_RS01955	COG2205	protein histidine kinase activity
CDL62_RS01955	COG0745	RESPONSE REGULATOR receiver
CDL62_RS01955	COG0745	RESPONSE REGULATOR receiver
CDL62_RS01965	COG0737	Belongs to the 5'-nucleotidase family
CDL62_RS01975	COG1522	sequence-specific DNA binding
CDL62_RS02025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDL62_RS02035	COG3250	beta-galactosidase activity
CDL62_RS02040	COG2207	Transcriptional regulator
CDL62_RS02050	COG2755	lipolytic protein G-D-S-L family
CDL62_RS02060	COG3254	rhamnose metabolic process
CDL62_RS02085	COG3401	FG-GAP repeat protein
CDL62_RS02090	COG3401	FG-GAP repeat protein
CDL62_RS02105	COG4771	TonB-dependent receptor
CDL62_RS02120	COG0702	epimerase
CDL62_RS02125	COG4771	TonB-dependent receptor
CDL62_RS02135	COG1621	beta-fructofuranosidase activity
CDL62_RS02150	COG4806	L-rhamnose isomerase
CDL62_RS02160	COG1063	alcohol dehydrogenase
CDL62_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS02180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDL62_RS02185	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDL62_RS02190	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS02200	COG0419	ATPase involved in DNA repair
CDL62_RS02215	COG0420	3'-5' exonuclease activity
CDL62_RS02240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDL62_RS02255	COG0702	epimerase
CDL62_RS02260	COG4771	TonB-dependent receptor
CDL62_RS02270	COG0745	RESPONSE REGULATOR receiver
CDL62_RS02270	COG3292	Two component regulator propeller
CDL62_RS02270	COG2205	protein histidine kinase activity
CDL62_RS02275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDL62_RS02295	COG4771	TonB-dependent receptor
CDL62_RS02300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDL62_RS02305	COG1185	polyribonucleotide nucleotidyltransferase activity
CDL62_RS02315	COG1505	serine-type exopeptidase activity
CDL62_RS02325	COG0366	Alpha amylase catalytic
CDL62_RS02335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CDL62_RS02345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDL62_RS02350	COG0045	succinate-CoA ligase (ADP-forming) activity
CDL62_RS02375	COG0628	permease
CDL62_RS02380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDL62_RS02390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDL62_RS02395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDL62_RS02405	COG3118	belongs to the thioredoxin family
CDL62_RS02410	COG0339	signal peptide processing
CDL62_RS02415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDL62_RS02420	COG1509	lysine 2,3-aminomutase activity
CDL62_RS02470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS02475	COG1473	amidohydrolase
CDL62_RS02500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDL62_RS02500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDL62_RS02510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDL62_RS02515	COG1435	thymidine kinase activity
CDL62_RS02525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDL62_RS02535	COG1011	Hydrolase
CDL62_RS02540	COG0305	Participates in initiation and elongation during chromosome replication
CDL62_RS02545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDL62_RS02550	COG3292	Two component regulator propeller
CDL62_RS02550	COG2205	protein histidine kinase activity
CDL62_RS02550	COG0745	RESPONSE REGULATOR receiver
CDL62_RS02555	COG0017	Asparaginyl-tRNA synthetase
CDL62_RS02565	COG0823	Involved in the tonB-independent uptake of proteins
CDL62_RS02565	COG1506	peptidase
CDL62_RS02575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDL62_RS02585	COG0343	queuine tRNA-ribosyltransferase activity
CDL62_RS02590	COG1215	transferase activity, transferring glycosyl groups
CDL62_RS02595	COG1595	DNA-templated transcription, initiation
CDL62_RS02600	COG0357	Ribosomal RNA small subunit methyltransferase G
CDL62_RS02615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDL62_RS02620	COG0515	serine threonine protein kinase
CDL62_RS02620	COG2815	serine threonine protein kinase
CDL62_RS02625	COG0564	pseudouridine synthase activity
CDL62_RS02630	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDL62_RS02640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CDL62_RS02660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDL62_RS02665	COG0436	Aminotransferase
CDL62_RS02670	COG0077	Prephenate dehydratase
CDL62_RS02680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDL62_RS02680	COG2205	protein histidine kinase activity
CDL62_RS02695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDL62_RS02700	COG1127	ABC transporter
CDL62_RS02705	COG0488	(ABC) transporter
CDL62_RS02710	COG0667	Aldo Keto reductase
CDL62_RS02720	COG0668	transmembrane transport
CDL62_RS02725	COG0450	alkyl hydroperoxide reductase
CDL62_RS02730	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDL62_RS02740	COG0442	prolyl-tRNA aminoacylation
CDL62_RS02755	COG1592	Rubrerythrin
CDL62_RS02760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDL62_RS02770	COG0295	cytidine deaminase activity
CDL62_RS02775	COG1722	exodeoxyribonuclease VII activity
CDL62_RS02785	COG1570	exodeoxyribonuclease VII activity
CDL62_RS02795	COG0443	Heat shock 70 kDa protein
CDL62_RS02800	COG0167	dihydroorotate dehydrogenase activity
CDL62_RS02805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDL62_RS02805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDL62_RS02825	COG1959	2 iron, 2 sulfur cluster binding
CDL62_RS02835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDL62_RS02840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDL62_RS02850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDL62_RS02850	COG1648	precorrin-2 dehydrogenase activity
CDL62_RS02870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDL62_RS02875	COG0460	homoserine dehydrogenase
CDL62_RS02900	COG0745	RESPONSE REGULATOR receiver
CDL62_RS02910	COG2226	methyltransferase
CDL62_RS02920	COG0745	RESPONSE REGULATOR receiver
CDL62_RS02955	COG4213	ABC transporter substrate-binding protein
CDL62_RS02960	COG2239	Acts as a magnesium transporter
CDL62_RS02965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDL62_RS03005	COG0823	Involved in the tonB-independent uptake of proteins
CDL62_RS03005	COG1506	peptidase
CDL62_RS03035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDL62_RS03045	COG1785	Belongs to the alkaline phosphatase family
CDL62_RS03070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDL62_RS03085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDL62_RS03090	COG1678	Uncharacterized ACR, COG1678
CDL62_RS03125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDL62_RS03135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDL62_RS03150	COG0783	Belongs to the Dps family
CDL62_RS03175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDL62_RS03180	COG0450	alkyl hydroperoxide reductase
CDL62_RS03185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDL62_RS03195	COG2197	response regulator
CDL62_RS03205	COG4771	TonB-dependent receptor
CDL62_RS03215	COG2304	oxidoreductase activity
CDL62_RS03240	COG0456	acetyltransferase
CDL62_RS03240	COG1214	PFAM Peptidase M22, glycoprotease
CDL62_RS03275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDL62_RS03275	COG5549	protein import
CDL62_RS03290	COG5549	protein import
CDL62_RS03290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDL62_RS03295	COG0488	(ABC) transporter
CDL62_RS03305	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CDL62_RS03310	COG0347	Belongs to the P(II) protein family
CDL62_RS03315	COG0347	Belongs to the P(II) protein family
CDL62_RS03330	COG0653	protein targeting
CDL62_RS03345	COG0535	radical SAM domain protein
CDL62_RS03345	COG1433	Dinitrogenase iron-molybdenum cofactor
CDL62_RS03355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDL62_RS03380	COG3585	molybdate ion transport
CDL62_RS03410	COG2205	protein histidine kinase activity
CDL62_RS03410	COG0784	Response regulator, receiver
CDL62_RS03420	COG0523	cobalamin synthesis protein
CDL62_RS03425	COG0523	cobalamin synthesis protein
CDL62_RS03430	COG1136	(ABC) transporter
CDL62_RS03445	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDL62_RS03480	COG1797	cobyrinic acid a,c-diamide synthase activity
CDL62_RS03485	COG1797	cobyrinic acid a,c-diamide synthase activity
CDL62_RS03490	COG4822	anaerobic cobalamin biosynthetic process
CDL62_RS03500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDL62_RS03515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDL62_RS03525	COG0840	transmembrane signaling receptor activity
CDL62_RS03530	COG0009	L-threonylcarbamoyladenylate synthase
CDL62_RS03535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDL62_RS03545	COG2204	response regulator
CDL62_RS03550	COG0784	Response regulator, receiver
CDL62_RS03550	COG2205	protein histidine kinase activity
CDL62_RS03555	COG0569	domain protein
CDL62_RS03560	COG0658	competence protein
CDL62_RS03560	COG2333	competence protein COMEC
CDL62_RS03570	COG3206	protein involved in exopolysaccharide biosynthesis
CDL62_RS03570	COG0489	protein tyrosine kinase activity
CDL62_RS03610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDL62_RS03625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDL62_RS03630	COG0463	Glycosyl transferase, family 2
CDL62_RS03645	COG0297	glycogen (starch) synthase activity
CDL62_RS03680	COG2089	acid synthase
CDL62_RS03690	COG1216	Glycosyl transferase, family 2
CDL62_RS03690	COG0463	Glycosyl transferase, family 2
CDL62_RS03695	COG1216	Glycosyl transferase, family 2
CDL62_RS03710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDL62_RS03710	COG2755	lipolytic protein G-D-S-L family
CDL62_RS03720	COG0110	maltose O-acetyltransferase activity
CDL62_RS03740	COG1132	(ABC) transporter
CDL62_RS03780	COG0242	peptide deformylase activity
CDL62_RS03785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDL62_RS03790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDL62_RS03790	COG0574	Belongs to the PEP-utilizing enzyme family
CDL62_RS03795	COG0167	dihydroorotate dehydrogenase activity
CDL62_RS03810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDL62_RS03815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDL62_RS03835	COG2205	protein histidine kinase activity
CDL62_RS03840	COG2201	protein-glutamate methylesterase activity
CDL62_RS03850	COG0840	transmembrane signaling receptor activity
CDL62_RS03855	COG0835	chemotaxis
CDL62_RS03865	COG2204	response regulator
CDL62_RS03875	COG0784	Response regulator, receiver
CDL62_RS03875	COG2205	protein histidine kinase activity
CDL62_RS03905	COG5000	phosphorelay sensor kinase activity
CDL62_RS03905	COG3279	Response regulator of the LytR AlgR family
CDL62_RS03920	COG1193	negative regulation of DNA recombination
CDL62_RS03935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDL62_RS03940	COG0564	pseudouridine synthase activity
CDL62_RS03965	COG0517	IMP dehydrogenase activity
CDL62_RS03965	COG0617	tRNA 3'-terminal CCA addition
CDL62_RS03965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDL62_RS03995	COG0039	L-malate dehydrogenase activity
CDL62_RS04010	COG1136	(ABC) transporter
CDL62_RS04010	COG0577	efflux transmembrane transporter activity
CDL62_RS04020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDL62_RS04025	COG3292	Two component regulator propeller
CDL62_RS04025	COG0745	RESPONSE REGULATOR receiver
CDL62_RS04025	COG2205	protein histidine kinase activity
CDL62_RS04030	COG1187	pseudouridine synthase activity
CDL62_RS04060	COG4335	DNA alkylation repair
CDL62_RS04070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDL62_RS04100	COG0463	Glycosyl transferase, family 2
CDL62_RS04105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDL62_RS04115	COG0527	aspartate kinase activity
CDL62_RS04120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDL62_RS04125	COG2197	response regulator
CDL62_RS04130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDL62_RS04150	COG1253	flavin adenine dinucleotide binding
CDL62_RS04155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDL62_RS04160	COG1610	YqeY-like protein
CDL62_RS04165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDL62_RS04180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDL62_RS04185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDL62_RS04190	COG0772	Belongs to the SEDS family
CDL62_RS04195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDL62_RS04200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDL62_RS04205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDL62_RS04210	COG0768	penicillin binding
CDL62_RS04220	COG0275	rRNA processing
CDL62_RS04225	COG2001	Belongs to the MraZ family
CDL62_RS04240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDL62_RS04250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDL62_RS04275	COG2081	HI0933 family
CDL62_RS04290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDL62_RS04295	COG0590	tRNA wobble adenosine to inosine editing
CDL62_RS04300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDL62_RS04325	COG0385	Bile acid
CDL62_RS04330	COG1022	Amp-dependent synthetase and ligase
CDL62_RS04380	COG0012	GTP binding
CDL62_RS04390	COG1595	DNA-templated transcription, initiation
CDL62_RS04405	COG0124	histidyl-tRNA synthetase
CDL62_RS04415	COG1840	ABC-type Fe3 transport system, periplasmic component
CDL62_RS04420	COG1178	ABC-type Fe3 transport system permease component
CDL62_RS04425	COG3842	ATPase activity
CDL62_RS04455	COG0488	(ABC) transporter
CDL62_RS04485	COG2205	protein histidine kinase activity
CDL62_RS04485	COG0745	RESPONSE REGULATOR receiver
CDL62_RS04485	COG3292	Two component regulator propeller
CDL62_RS04495	COG0148	phosphopyruvate hydratase activity
CDL62_RS04500	COG0203	ribosomal protein L17
CDL62_RS04505	COG0202	RNA polymerase activity
CDL62_RS04510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDL62_RS04515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDL62_RS04520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDL62_RS04525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDL62_RS04530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDL62_RS04545	COG0200	Binds to the 23S rRNA
CDL62_RS04550	COG1841	ribosomal large subunit assembly
CDL62_RS04555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDL62_RS04560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDL62_RS04565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDL62_RS04570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDL62_RS04575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDL62_RS04580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDL62_RS04585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDL62_RS04590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDL62_RS04595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDL62_RS04600	COG0255	Belongs to the universal ribosomal protein uL29 family
CDL62_RS04605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDL62_RS04610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDL62_RS04615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDL62_RS04620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDL62_RS04625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDL62_RS04630	COG0089	rRNA binding
CDL62_RS04635	COG0088	Forms part of the polypeptide exit tunnel
CDL62_RS04640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDL62_RS04645	COG0051	transcription antitermination factor activity, RNA binding
CDL62_RS04650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDL62_RS04655	COG0049	tRNA binding
CDL62_RS04660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDL62_RS04665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDL62_RS04670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDL62_RS04685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDL62_RS04715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDL62_RS04720	COG1160	GTP binding
CDL62_RS04730	COG0788	formyltetrahydrofolate deformylase activity
CDL62_RS04735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDL62_RS04745	COG0107	imidazoleglycerol-phosphate synthase activity
CDL62_RS04790	COG1518	maintenance of DNA repeat elements
CDL62_RS04795	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDL62_RS04810	COG2205	protein histidine kinase activity
CDL62_RS04820	COG0157	Belongs to the NadC ModD family
CDL62_RS04830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDL62_RS04835	COG5000	phosphorelay sensor kinase activity
CDL62_RS04855	COG0596	Alpha beta hydrolase
CDL62_RS04875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDL62_RS04885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDL62_RS04890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDL62_RS04910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDL62_RS04915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDL62_RS04920	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDL62_RS04920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDL62_RS04925	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDL62_RS04990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDL62_RS04995	COG0494	nUDIX hydrolase
CDL62_RS05005	COG1993	acr, cog1993
CDL62_RS05015	COG0159	tryptophan synthase activity
CDL62_RS05020	COG0133	tryptophan synthase activity
CDL62_RS05025	COG0135	phosphoribosylanthranilate isomerase activity
CDL62_RS05030	COG0134	indole-3-glycerol-phosphate synthase activity
CDL62_RS05040	COG3385	transposase activity
CDL62_RS05050	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS05055	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDL62_RS05070	COG0702	epimerase
CDL62_RS05075	COG4771	TonB-dependent receptor
CDL62_RS05120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDL62_RS05125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDL62_RS05125	COG0512	Glutamine amidotransferase of anthranilate synthase
CDL62_RS05180	COG0484	heat shock protein binding
CDL62_RS05185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDL62_RS05195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDL62_RS05230	COG0019	diaminopimelate decarboxylase activity
CDL62_RS05235	COG0527	aspartate kinase activity
CDL62_RS05240	COG1482	cell wall glycoprotein biosynthetic process
CDL62_RS05245	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDL62_RS05250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDL62_RS05255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDL62_RS05260	COG0193	aminoacyl-tRNA hydrolase activity
CDL62_RS05265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDL62_RS05295	COG2885	chlorophyll binding
CDL62_RS05305	COG0525	valine-tRNA ligase activity
CDL62_RS05325	COG2197	response regulator
CDL62_RS05330	COG2205	protein histidine kinase activity
CDL62_RS05330	COG0784	Response regulator, receiver
CDL62_RS05340	COG0436	Aminotransferase
CDL62_RS05350	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CDL62_RS05365	COG4535	Mg2 and Co2 transporter CorC
CDL62_RS05370	COG0629	single-stranded DNA binding
CDL62_RS05380	COG0776	regulation of translation
CDL62_RS05385	COG1530	ribonuclease E activity
CDL62_RS05390	COG0589	response to stress
CDL62_RS05390	COG0475	glutathione-regulated potassium exporter activity
CDL62_RS05405	COG1959	2 iron, 2 sulfur cluster binding
CDL62_RS05410	COG4152	abc transporter atp-binding protein
CDL62_RS05420	COG0248	Ppx GppA phosphatase
CDL62_RS05440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDL62_RS05470	COG2814	Major facilitator Superfamily
CDL62_RS05485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDL62_RS05490	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS05560	COG0505	Belongs to the CarA family
CDL62_RS05565	COG0372	Belongs to the citrate synthase family
CDL62_RS05570	COG0165	Argininosuccinate lyase
CDL62_RS05580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDL62_RS05590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDL62_RS05595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDL62_RS05600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDL62_RS05615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDL62_RS05620	COG0137	argininosuccinate synthase activity
CDL62_RS05630	COG1438	arginine binding
CDL62_RS05635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDL62_RS05640	COG1082	Xylose isomerase domain protein TIM barrel
CDL62_RS05645	COG1183	phosphatidylcholine synthase activity
CDL62_RS05660	COG2703	oxygen carrier activity
CDL62_RS05665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDL62_RS05665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDL62_RS05675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDL62_RS05680	COG2610	gluconate transmembrane transporter activity
CDL62_RS05690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDL62_RS05700	COG2382	esterase
CDL62_RS05710	COG0667	Aldo Keto reductase
CDL62_RS05720	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDL62_RS05720	COG0131	Imidazoleglycerol-phosphate dehydratase
CDL62_RS05725	COG2755	lipolytic protein G-D-S-L family
CDL62_RS05725	COG0657	acetylesterase activity
CDL62_RS05730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDL62_RS05735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDL62_RS05740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDL62_RS05745	COG1957	nucleoside hydrolase
CDL62_RS05775	COG1294	oxidase, subunit
CDL62_RS05795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDL62_RS05810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDL62_RS05820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDL62_RS05820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDL62_RS05825	COG0799	negative regulation of ribosome biogenesis
CDL62_RS05830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDL62_RS05835	COG1556	Lactate utilization protein
CDL62_RS05845	COG0688	phosphatidylethanolamine metabolic process
CDL62_RS05870	COG3292	Two component regulator propeller
CDL62_RS05870	COG0745	RESPONSE REGULATOR receiver
CDL62_RS05870	COG3292	Two component regulator propeller
CDL62_RS05870	COG2205	protein histidine kinase activity
CDL62_RS05870	COG0745	RESPONSE REGULATOR receiver
CDL62_RS05870	COG2205	protein histidine kinase activity
CDL62_RS05895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDL62_RS05900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDL62_RS05900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDL62_RS05905	COG2890	protein-(glutamine-N5) methyltransferase activity
CDL62_RS05920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS05925	COG3250	beta-galactosidase activity
CDL62_RS05965	COG0823	Involved in the tonB-independent uptake of proteins
CDL62_RS05965	COG1506	peptidase
CDL62_RS05975	COG2721	sulfolactate sulfo-lyase activity
CDL62_RS05980	COG0246	Mannitol dehydrogenase
CDL62_RS06000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDL62_RS06005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDL62_RS06020	COG1757	Na H antiporter
CDL62_RS06025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDL62_RS06030	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDL62_RS06045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDL62_RS06070	COG0805	protein transport
CDL62_RS06075	COG0514	ATP-dependent DNA helicase (RecQ)
CDL62_RS06090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDL62_RS06095	COG0563	adenylate kinase activity
CDL62_RS06100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDL62_RS06105	COG0745	RESPONSE REGULATOR receiver
CDL62_RS06105	COG3292	Two component regulator propeller
CDL62_RS06105	COG2205	protein histidine kinase activity
CDL62_RS06125	COG0702	epimerase
CDL62_RS06130	COG4771	TonB-dependent receptor
CDL62_RS06135	COG0702	epimerase
CDL62_RS06140	COG1629	transport
CDL62_RS06150	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06165	COG3250	beta-galactosidase activity
CDL62_RS06175	COG3693	PFAM glycoside hydrolase, family 10
CDL62_RS06175	COG2382	esterase
CDL62_RS06175	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06180	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06185	COG2382	esterase
CDL62_RS06205	COG2382	esterase
CDL62_RS06215	COG3693	PFAM glycoside hydrolase, family 10
CDL62_RS06215	COG2382	esterase
CDL62_RS06220	COG3693	PFAM glycoside hydrolase, family 10
CDL62_RS06220	COG2382	esterase
CDL62_RS06225	COG2382	esterase
CDL62_RS06230	COG2272	Belongs to the type-B carboxylesterase lipase family
CDL62_RS06255	COG0673	inositol 2-dehydrogenase activity
CDL62_RS06265	COG5520	Belongs to the glycosyl hydrolase 30 family
CDL62_RS06275	COG3534	alpha-L-arabinofuranosidase
CDL62_RS06280	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06285	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06290	COG1082	Xylose isomerase domain protein TIM barrel
CDL62_RS06305	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS06310	COG1501	Belongs to the glycosyl hydrolase 31 family
CDL62_RS06315	COG1082	Xylose isomerase domain protein TIM barrel
CDL62_RS06320	COG1501	Belongs to the glycosyl hydrolase 31 family
CDL62_RS06330	COG3250	beta-galactosidase activity
CDL62_RS06340	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS06345	COG1063	alcohol dehydrogenase
CDL62_RS06350	COG0656	L-ascorbic acid biosynthetic process
CDL62_RS06355	COG0738	Major facilitator superfamily
CDL62_RS06390	COG0726	polysaccharide deacetylase
CDL62_RS06410	COG0702	epimerase
CDL62_RS06415	COG4206	TonB-dependent receptor
CDL62_RS06415	COG1629	transport
CDL62_RS06425	COG4771	TonB-dependent receptor
CDL62_RS06430	COG0745	RESPONSE REGULATOR receiver
CDL62_RS06430	COG2205	protein histidine kinase activity
CDL62_RS06430	COG3292	Two component regulator propeller
CDL62_RS06445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDL62_RS06455	COG2017	converts alpha-aldose to the beta-anomer
CDL62_RS06480	COG2160	L-arabinose isomerase activity
CDL62_RS06495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDL62_RS06500	COG0254	rRNA binding
CDL62_RS06525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDL62_RS06530	COG1393	Belongs to the ArsC family
CDL62_RS06535	COG0196	riboflavin kinase activity
CDL62_RS06540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDL62_RS06555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDL62_RS06565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDL62_RS06575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDL62_RS06580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDL62_RS06585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDL62_RS06650	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CDL62_RS06685	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDL62_RS06690	COG1121	(ABC) transporter
CDL62_RS06695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDL62_RS06700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDL62_RS06705	COG1040	competence protein
CDL62_RS06710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDL62_RS06715	COG0138	bifunctional purine biosynthesis protein purh
CDL62_RS06735	COG0768	penicillin binding
CDL62_RS06740	COG0772	Belongs to the SEDS family
CDL62_RS06745	COG1509	lysine 2,3-aminomutase activity
CDL62_RS06755	COG1131	(ABC) transporter
CDL62_RS06755	COG1716	ATPase activity
CDL62_RS06755	COG0842	Transport permease protein
CDL62_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS06770	COG2207	Transcriptional regulator
CDL62_RS06770	COG0662	Cupin 2, conserved barrel domain protein
CDL62_RS06795	COG1012	belongs to the aldehyde dehydrogenase family
CDL62_RS06820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDL62_RS06825	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDL62_RS06835	COG0714	Associated with various cellular activities
CDL62_RS06870	COG0741	lytic transglycosylase activity
CDL62_RS06880	COG1475	DNA binding
CDL62_RS06885	COG1192	Involved in chromosome partitioning
CDL62_RS06900	COG4221	oxidoreductase activity
CDL62_RS06905	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDL62_RS06915	COG0606	chelatase, subunit chli
CDL62_RS06930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDL62_RS06930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDL62_RS06935	COG0321	lipoyl(octanoyl) transferase activity
CDL62_RS06940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDL62_RS06950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDL62_RS06955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDL62_RS06960	COG0166	Belongs to the GPI family
CDL62_RS06970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDL62_RS06990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDL62_RS07005	COG4771	TonB-dependent receptor
CDL62_RS07015	COG1629	transport
CDL62_RS07035	COG0668	transmembrane transport
CDL62_RS07055	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDL62_RS07060	COG1691	(AIR) carboxylase
CDL62_RS07070	COG1022	Amp-dependent synthetase and ligase
CDL62_RS07080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDL62_RS07090	COG0427	acetyl-CoA hydrolase
CDL62_RS07095	COG0259	pyridoxamine-phosphate oxidase activity
CDL62_RS07100	COG1131	(ABC) transporter
CDL62_RS07105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDL62_RS07115	COG5002	protein histidine kinase activity
CDL62_RS07120	COG0745	RESPONSE REGULATOR receiver
CDL62_RS07130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDL62_RS07135	COG0581	inorganic phosphate transmembrane transporter activity
CDL62_RS07140	COG0573	inorganic phosphate transmembrane transporter activity
CDL62_RS07145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDL62_RS07150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDL62_RS07185	COG1011	Hydrolase
CDL62_RS07200	COG0463	Glycosyl transferase, family 2
CDL62_RS07215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDL62_RS07220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDL62_RS07235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDL62_RS07240	COG3273	potassium ion transport
CDL62_RS07240	COG0471	metal ion transport
CDL62_RS07250	COG2239	Acts as a magnesium transporter
CDL62_RS07255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDL62_RS07275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDL62_RS07280	COG3118	belongs to the thioredoxin family
CDL62_RS07290	COG4124	Belongs to the glycosyl hydrolase 26 family
CDL62_RS07295	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CDL62_RS07300	COG2942	2-epimerase
CDL62_RS07305	COG2211	Major facilitator Superfamily
CDL62_RS07315	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDL62_RS07330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDL62_RS07365	COG0066	3-isopropylmalate dehydratase activity
CDL62_RS07370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDL62_RS07375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDL62_RS07380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDL62_RS07390	COG0028	Belongs to the TPP enzyme family
CDL62_RS07395	COG0129	dihydroxy-acid dehydratase activity
CDL62_RS07435	COG1131	(ABC) transporter
CDL62_RS07445	COG2171	N-acyltransferase activity
CDL62_RS07450	COG0009	L-threonylcarbamoyladenylate synthase
CDL62_RS07460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDL62_RS07465	COG0228	four-way junction DNA binding
CDL62_RS07470	COG2207	Transcriptional regulator
CDL62_RS07470	COG0662	Cupin 2, conserved barrel domain protein
CDL62_RS07480	COG0700	Nucleoside recognition
CDL62_RS07500	COG0358	DNA primase activity
CDL62_RS07510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDL62_RS07540	COG1595	DNA-templated transcription, initiation
CDL62_RS07550	COG2873	o-acetylhomoserine
CDL62_RS07555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDL62_RS07560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDL62_RS07565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDL62_RS07570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDL62_RS07575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDL62_RS07580	COG0356	it plays a direct role in the translocation of protons across the membrane
CDL62_RS07600	COG0589	response to stress
CDL62_RS07605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDL62_RS07635	COG0826	peptidase U32
CDL62_RS07665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDL62_RS07690	COG0840	transmembrane signaling receptor activity
CDL62_RS07700	COG0745	RESPONSE REGULATOR receiver
CDL62_RS07710	COG2198	Histidine kinase
CDL62_RS07710	COG0643	Histidine kinase
CDL62_RS07715	COG0835	chemotaxis
CDL62_RS07735	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDL62_RS07740	COG2201	protein-glutamate methylesterase activity
CDL62_RS07750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDL62_RS07755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDL62_RS07785	COG1131	(ABC) transporter
CDL62_RS07785	COG0842	Transport permease protein
CDL62_RS07785	COG1716	ATPase activity
CDL62_RS07800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDL62_RS07810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDL62_RS07820	COG1959	2 iron, 2 sulfur cluster binding
CDL62_RS07830	COG0698	ribose 5-phosphate isomerase
CDL62_RS07835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDL62_RS07840	COG2198	Histidine kinase
CDL62_RS07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDL62_RS07840	COG2205	protein histidine kinase activity
CDL62_RS07840	COG0784	Response regulator, receiver
CDL62_RS07845	COG2255	four-way junction helicase activity
CDL62_RS07855	COG0756	dUTP diphosphatase activity
CDL62_RS07880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDL62_RS07885	COG0445	tRNA wobble uridine modification
CDL62_RS07890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDL62_RS07895	COG0322	excinuclease ABC activity
CDL62_RS07905	COG1490	D-aminoacyl-tRNA deacylase activity
CDL62_RS07910	COG1694	Mazg nucleotide pyrophosphohydrolase
CDL62_RS07915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDL62_RS07925	COG0142	geranyltranstransferase activity
CDL62_RS07935	COG0720	synthase
CDL62_RS07945	COG0702	epimerase
CDL62_RS07960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDL62_RS07960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDL62_RS07990	COG2268	Band 7 protein
CDL62_RS08005	COG3853	Toxic anion resistance protein (TelA)
CDL62_RS08015	COG0793	Belongs to the peptidase S41A family
CDL62_RS08025	COG2131	deaminase
CDL62_RS08030	COG0793	Belongs to the peptidase S41A family
CDL62_RS08040	COG0175	sulfate reduction
CDL62_RS08045	COG0205	6-phosphofructokinase activity
CDL62_RS08055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDL62_RS08060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDL62_RS08065	COG1968	undecaprenyl-diphosphatase activity
CDL62_RS08075	COG2177	Part of the ABC transporter FtsEX involved in
CDL62_RS08105	COG2205	protein histidine kinase activity
CDL62_RS08105	COG3437	response regulator, receiver
CDL62_RS08105	COG3850	Histidine kinase
CDL62_RS08105	COG4999	Histidine kinase
CDL62_RS08115	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS08120	COG1216	Glycosyl transferase, family 2
CDL62_RS08165	COG1428	Deoxynucleoside kinase
CDL62_RS08195	COG0594	ribonuclease P activity
CDL62_RS08200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDL62_RS08215	COG2205	protein histidine kinase activity
CDL62_RS08215	COG0784	Response regulator, receiver
CDL62_RS08225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDL62_RS08230	COG2198	Histidine kinase
CDL62_RS08230	COG5002	protein histidine kinase activity
CDL62_RS08230	COG0784	Response regulator, receiver
CDL62_RS08250	COG1217	gtp-binding protein TYPA
CDL62_RS08255	COG1254	Belongs to the acylphosphatase family
CDL62_RS08265	COG0156	8-amino-7-oxononanoate synthase activity
CDL62_RS08275	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDL62_RS08300	COG0564	pseudouridine synthase activity
CDL62_RS08305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDL62_RS08315	COG3609	addiction module antidote protein, CC2985 family
CDL62_RS08330	COG2897	thiosulfate sulfurtransferase activity
CDL62_RS08345	COG2211	Major facilitator Superfamily
CDL62_RS08355	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDL62_RS08385	COG3321	synthase
CDL62_RS08385	COG0604	alcohol dehydrogenase
CDL62_RS08410	COG2226	methyltransferase
CDL62_RS08425	COG0537	adenosine 5'-monophosphoramidase activity
CDL62_RS08465	COG0840	transmembrane signaling receptor activity
CDL62_RS08465	COG3290	protein histidine kinase activity
CDL62_RS08470	COG0436	Aminotransferase
CDL62_RS08495	COG2198	Histidine kinase
CDL62_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDL62_RS08495	COG2205	protein histidine kinase activity
CDL62_RS08495	COG0784	Response regulator, receiver
CDL62_RS08505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDL62_RS08520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDL62_RS08525	COG0233	cytoplasmic translational termination
CDL62_RS08535	COG1606	tRNA processing
CDL62_RS08560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDL62_RS08565	COG0577	efflux transmembrane transporter activity
CDL62_RS08565	COG1136	(ABC) transporter
CDL62_RS08570	COG1136	(ABC) transporter
CDL62_RS08570	COG0577	efflux transmembrane transporter activity
CDL62_RS08575	COG1136	(ABC) transporter
CDL62_RS08595	COG2116	formate transmembrane transporter activity
CDL62_RS08600	COG0612	Peptidase, M16
CDL62_RS08605	COG0612	Peptidase, M16
CDL62_RS08630	COG0561	phosphatase activity
CDL62_RS08645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDL62_RS08655	COG4251	negative regulation of phosphorylation
CDL62_RS08660	COG2226	methyltransferase
CDL62_RS08665	COG4584	PFAM Integrase catalytic
CDL62_RS08665	COG2390	Transcriptional regulator
CDL62_RS08670	COG1484	DNA-dependent DNA replication
CDL62_RS08675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDL62_RS08710	COG4771	TonB-dependent receptor
CDL62_RS08750	COG0151	Belongs to the GarS family
CDL62_RS08775	COG0514	ATP-dependent DNA helicase (RecQ)
CDL62_RS08790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDL62_RS08795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDL62_RS08805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDL62_RS08810	COG0798	PFAM Bile acid sodium symporter
CDL62_RS08870	COG4191	Histidine kinase
CDL62_RS08870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDL62_RS08880	COG0471	metal ion transport
CDL62_RS08890	COG2957	Belongs to the agmatine deiminase family
CDL62_RS08905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDL62_RS08905	COG1333	cytochrome c biogenesis protein
CDL62_RS08910	COG1595	DNA-templated transcription, initiation
CDL62_RS08955	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CDL62_RS08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDL62_RS08970	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDL62_RS08985	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDL62_RS08995	COG0590	tRNA wobble adenosine to inosine editing
CDL62_RS09015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS09035	COG0528	UMP kinase activity
CDL62_RS09040	COG0784	Response regulator, receiver
CDL62_RS09040	COG2205	protein histidine kinase activity
CDL62_RS09075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDL62_RS09085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDL62_RS09090	COG0052	Belongs to the universal ribosomal protein uS2 family
CDL62_RS09095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDL62_RS09100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDL62_RS09125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDL62_RS09130	COG1053	succinate dehydrogenase
CDL62_RS09145	COG0180	Tryptophanyl-tRNA synthetase
CDL62_RS09150	COG2201	protein-glutamate methylesterase activity
CDL62_RS09160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDL62_RS09165	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDL62_RS09175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDL62_RS09185	COG1695	Transcriptional regulator
CDL62_RS09260	COG2311	Membrane
CDL62_RS09265	COG0545	Peptidyl-prolyl cis-trans isomerase
CDL62_RS09270	COG2223	nitrite transmembrane transporter activity
CDL62_RS09310	COG0268	Binds directly to 16S ribosomal RNA
CDL62_RS09320	COG2003	Belongs to the UPF0758 family
CDL62_RS09330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDL62_RS09340	COG0616	signal peptide processing
CDL62_RS09345	COG1663	tetraacyldisaccharide 4'-kinase activity
CDL62_RS09355	COG0840	transmembrane signaling receptor activity
CDL62_RS09365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDL62_RS09380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDL62_RS09390	COG0307	riboflavin synthase, alpha
CDL62_RS09400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDL62_RS09405	COG2340	Cysteine-rich secretory protein family
CDL62_RS09420	COG0423	glycine-tRNA ligase activity
CDL62_RS09425	COG3263	regulation of cellular component size
CDL62_RS09435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDL62_RS09445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDL62_RS09450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDL62_RS09455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CDL62_RS09460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDL62_RS09465	COG0297	glycogen (starch) synthase activity
CDL62_RS09475	COG0363	glucosamine-6-phosphate deaminase activity
CDL62_RS09485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDL62_RS09495	COG0673	inositol 2-dehydrogenase activity
CDL62_RS09510	COG0463	Glycosyl transferase, family 2
CDL62_RS09530	COG0662	Cupin 2, conserved barrel domain protein
CDL62_RS09535	COG2176	DNA-directed DNA polymerase activity
CDL62_RS09550	COG2755	lipolytic protein G-D-S-L family
CDL62_RS09555	COG2271	Major facilitator Superfamily
CDL62_RS09560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDL62_RS09570	COG0483	inositol monophosphate 1-phosphatase activity
CDL62_RS09600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDL62_RS09615	COG1360	Flagellar Motor Protein
CDL62_RS09655	COG3119	arylsulfatase activity
CDL62_RS09660	COG3119	arylsulfatase activity
CDL62_RS09665	COG0641	radical SAM
CDL62_RS09680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDL62_RS09685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDL62_RS09695	COG2205	protein histidine kinase activity
CDL62_RS09695	COG3292	Two component regulator propeller
CDL62_RS09695	COG0745	RESPONSE REGULATOR receiver
CDL62_RS09705	COG1162	GTPase activity
CDL62_RS09725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDL62_RS09750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDL62_RS09755	COG1127	ABC transporter
CDL62_RS09795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDL62_RS09795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CDL62_RS09835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDL62_RS09890	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS09910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDL62_RS09945	COG3275	phosphorelay sensor kinase activity
CDL62_RS09950	COG3279	Response regulator of the LytR AlgR family
CDL62_RS09960	COG0731	radical SAM domain protein
CDL62_RS09960	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDL62_RS10000	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS10005	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS10015	COG1519	Transferase
CDL62_RS10020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDL62_RS10030	COG3275	phosphorelay sensor kinase activity
CDL62_RS10040	COG3591	Belongs to the peptidase S1B family
CDL62_RS10050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDL62_RS10060	COG0215	cysteine-tRNA ligase activity
CDL62_RS10095	COG0557	exoribonuclease II activity
CDL62_RS10105	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDL62_RS10110	COG3341	Caulimovirus viroplasmin
CDL62_RS10110	COG0328	RNA-DNA hybrid ribonuclease activity
CDL62_RS10125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDL62_RS10145	COG0126	phosphoglycerate kinase activity
CDL62_RS10155	COG0470	DNA polymerase III
CDL62_RS10160	COG1774	PSP1 C-terminal conserved region
CDL62_RS10170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDL62_RS10180	COG0489	protein tyrosine kinase activity
CDL62_RS10185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDL62_RS10185	COG0316	Belongs to the HesB IscA family
CDL62_RS10190	COG0686	Belongs to the AlaDH PNT family
CDL62_RS10195	COG0802	atpase or kinase
CDL62_RS10200	COG2204	response regulator
CDL62_RS10215	COG2204	response regulator
CDL62_RS10220	COG0509	glycine decarboxylation via glycine cleavage system
CDL62_RS10225	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDL62_RS10230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDL62_RS10245	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS10265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDL62_RS10270	COG2151	metal-sulfur cluster biosynthetic enzyme
CDL62_RS10275	COG2166	iron-sulfur cluster assembly
CDL62_RS10280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDL62_RS10285	COG0719	Fe-S assembly protein
CDL62_RS10290	COG0396	ATPase activity
CDL62_RS10295	COG0719	Fe-S assembly protein
CDL62_RS10300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDL62_RS10320	COG1078	dGTPase activity
CDL62_RS10325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDL62_RS10330	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CDL62_RS10330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDL62_RS10335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDL62_RS10340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDL62_RS10345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDL62_RS10365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDL62_RS10370	COG0750	zinc metalloprotease
CDL62_RS10375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDL62_RS10380	COG4942	peptidase
CDL62_RS10390	COG0668	transmembrane transport
CDL62_RS10395	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDL62_RS10400	COG1518	maintenance of DNA repeat elements
CDL62_RS10425	COG1203	CRISPR-associated helicase, Cas3
CDL62_RS10460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDL62_RS10465	COG0195	Participates in both transcription termination and antitermination
CDL62_RS10470	COG0779	Required for maturation of 30S ribosomal subunits
CDL62_RS10485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDL62_RS10490	COG0632	four-way junction helicase activity
CDL62_RS10520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDL62_RS10525	COG0459	protein refolding
CDL62_RS10530	COG0481	GTPase activity
CDL62_RS10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDL62_RS10555	COG0302	gtp cyclohydrolase
CDL62_RS10565	COG1629	transport
CDL62_RS10595	COG0811	peptide transport
CDL62_RS10600	COG0252	asparaginase activity
CDL62_RS10605	COG0084	hydrolase, TatD family'
CDL62_RS10615	COG0534	Mate efflux family protein
CDL62_RS10620	COG0506	proline dehydrogenase activity
CDL62_RS10625	COG3291	Pkd domain containing protein
CDL62_RS10635	COG0071	Belongs to the small heat shock protein (HSP20) family
CDL62_RS10640	COG1278	Cold shock
CDL62_RS10660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDL62_RS10665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDL62_RS10680	COG0758	DNA mediated transformation
CDL62_RS10680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDL62_RS10685	COG0247	lactate metabolic process
CDL62_RS10685	COG0277	FAD linked oxidase domain protein
CDL62_RS10695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDL62_RS10700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDL62_RS10705	COG1120	ATPase activity
CDL62_RS10750	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CDL62_RS10760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDL62_RS10770	COG3852	Histidine kinase
CDL62_RS10795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDL62_RS10795	COG2205	protein histidine kinase activity
CDL62_RS10800	COG1492	cobalamin metabolic process
CDL62_RS10815	COG0384	phenazine biosynthesis protein PhzF
CDL62_RS10855	COG3920	Histidine kinase
CDL62_RS10855	COG2202	Pas domain
CDL62_RS10885	COG2755	lipolytic protein G-D-S-L family
CDL62_RS10885	COG0657	acetylesterase activity
CDL62_RS10925	COG0442	prolyl-tRNA aminoacylation
CDL62_RS10935	COG0676	glucose-6-phosphate 1-epimerase activity
CDL62_RS10940	COG0495	leucyl-tRNA aminoacylation
CDL62_RS10960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDL62_RS10965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDL62_RS10970	COG0571	ribonuclease III activity
CDL62_RS10990	COG3291	Pkd domain containing protein
CDL62_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
CDL62_RS11030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CDL62_RS11035	COG1805	sodium ion transport
CDL62_RS11040	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CDL62_RS11050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CDL62_RS11055	COG2871	sodium ion transport
CDL62_RS11060	COG1477	protein flavinylation
CDL62_RS11065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDL62_RS11070	COG0739	heme binding
CDL62_RS11075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDL62_RS11080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDL62_RS11115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDL62_RS11125	COG2843	Capsule synthesis protein
CDL62_RS11130	COG0716	FMN binding
CDL62_RS11155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDL62_RS11160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDL62_RS11170	COG1136	(ABC) transporter
CDL62_RS11180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDL62_RS11185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDL62_RS11190	COG1136	(ABC) transporter
CDL62_RS11190	COG0577	efflux transmembrane transporter activity
CDL62_RS11195	COG1136	(ABC) transporter
CDL62_RS11195	COG0577	efflux transmembrane transporter activity
CDL62_RS11205	COG4191	Histidine kinase
CDL62_RS11210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDL62_RS11225	COG0285	dihydrofolate synthase activity
CDL62_RS11230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDL62_RS11235	COG0483	inositol monophosphate 1-phosphatase activity
CDL62_RS11245	COG1215	transferase activity, transferring glycosyl groups
CDL62_RS11250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDL62_RS11255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDL62_RS11270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDL62_RS11275	COG3118	belongs to the thioredoxin family
CDL62_RS11275	COG0492	ferredoxin-NADP+ reductase activity
CDL62_RS11280	COG1278	Cold shock
CDL62_RS11285	COG1022	Amp-dependent synthetase and ligase
CDL62_RS11295	COG0612	Peptidase, M16
CDL62_RS11310	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDL62_RS11320	COG0217	transcriptional regulatory protein
CDL62_RS11325	COG0745	RESPONSE REGULATOR receiver
CDL62_RS11325	COG2205	protein histidine kinase activity
CDL62_RS11325	COG3292	Two component regulator propeller
CDL62_RS11345	COG0367	asparagine synthase
CDL62_RS11350	COG0070	glutamate synthase
CDL62_RS11350	COG0069	glutamate synthase activity
CDL62_RS11350	COG0067	glutamate synthase
CDL62_RS11365	COG0531	amino acid
CDL62_RS11390	COG0784	Response regulator, receiver
CDL62_RS11390	COG2205	protein histidine kinase activity
CDL62_RS11390	COG5002	protein histidine kinase activity
CDL62_RS11400	COG1501	Belongs to the glycosyl hydrolase 31 family
CDL62_RS11405	COG0366	Alpha amylase catalytic
CDL62_RS11415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDL62_RS11430	COG4206	TonB-dependent receptor
CDL62_RS11430	COG1629	transport
CDL62_RS11450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDL62_RS11455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDL62_RS11460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDL62_RS11465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDL62_RS11465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDL62_RS11480	COG3292	Two component regulator propeller
CDL62_RS11480	COG2205	protein histidine kinase activity
CDL62_RS11480	COG0745	RESPONSE REGULATOR receiver
CDL62_RS11485	COG0673	inositol 2-dehydrogenase activity
CDL62_RS11495	COG3275	phosphorelay sensor kinase activity
CDL62_RS11525	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDL62_RS11650	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CDL62_RS11705	COG2217	Heavy metal translocating P-type atpase
CDL62_RS11720	COG0784	Response regulator, receiver
CDL62_RS11720	COG2205	protein histidine kinase activity
CDL62_RS11730	COG0523	cobalamin synthesis protein
CDL62_RS11740	COG3621	Patatin-like phospholipase
CDL62_RS11760	COG0477	Major facilitator Superfamily
CDL62_RS11760	COG2814	Major facilitator Superfamily
CDL62_RS11765	COG0457	Tetratricopeptide repeat
CDL62_RS11780	COG0071	Belongs to the small heat shock protein (HSP20) family
CDL62_RS11785	COG0071	Belongs to the small heat shock protein (HSP20) family
CDL62_RS11795	COG5297	Belongs to the glycosyl hydrolase family 6
CDL62_RS11795	COG4733	cellulase activity
CDL62_RS11815	COG5002	protein histidine kinase activity
CDL62_RS11820	COG0745	RESPONSE REGULATOR receiver
CDL62_RS11830	COG4221	oxidoreductase activity
CDL62_RS11835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDL62_RS11840	COG2226	methyltransferase
CDL62_RS11850	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CDL62_RS11855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDL62_RS11865	COG0191	fructose-bisphosphate aldolase activity
CDL62_RS11880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDL62_RS11885	COG4974	Belongs to the 'phage' integrase family
CDL62_RS11905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDL62_RS11925	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDL62_RS11930	COG0081	regulation of translation
CDL62_RS11935	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDL62_RS11940	COG0222	ribosome binding
CDL62_RS11945	COG0085	RNA polymerase activity
CDL62_RS11950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDL62_RS11965	COG3866	Pectate lyase
CDL62_RS11970	COG1472	Belongs to the glycosyl hydrolase 3 family
CDL62_RS11975	COG1643	Atp-dependent helicase
CDL62_RS12025	COG3279	Response regulator of the LytR AlgR family
CDL62_RS12030	COG3279	Response regulator of the LytR AlgR family
CDL62_RS12035	COG1408	metallophosphoesterase
CDL62_RS12040	COG0612	Peptidase, M16
CDL62_RS12065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDL62_RS12065	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDL62_RS12070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDL62_RS12075	COG3153	acetyltransferase
CDL62_RS12075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDL62_RS12095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDL62_RS12100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDL62_RS12105	COG1169	isochorismate synthase
CDL62_RS12110	COG4771	TonB-dependent receptor
CDL62_RS12145	COG4152	abc transporter atp-binding protein
CDL62_RS12155	COG3275	phosphorelay sensor kinase activity
CDL62_RS12160	COG3279	Response regulator of the LytR AlgR family
CDL62_RS12175	COG1704	LemA family
CDL62_RS12200	COG1233	COG1233 Phytoene dehydrogenase and related
CDL62_RS12250	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDL62_RS12260	COG1136	(ABC) transporter
CDL62_RS12270	COG1510	regulation of RNA biosynthetic process
CDL62_RS12290	COG4771	TonB-dependent receptor
CDL62_RS12310	COG4771	TonB-dependent receptor
CDL62_RS12335	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS12340	COG3250	beta-galactosidase activity
CDL62_RS12345	COG1501	Belongs to the glycosyl hydrolase 31 family
CDL62_RS12350	COG4948	Mandelate Racemase Muconate Lactonizing
CDL62_RS12360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDL62_RS12370	COG0784	Response regulator, receiver
CDL62_RS12370	COG2205	protein histidine kinase activity
CDL62_RS12370	COG5002	protein histidine kinase activity
CDL62_RS12405	COG1597	lipid kinase activity
CDL62_RS12420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDL62_RS12450	COG1940	carbohydrate kinase activity
CDL62_RS12455	COG0133	tryptophan synthase activity
CDL62_RS12460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CDL62_RS12465	COG0738	Major facilitator superfamily
CDL62_RS12480	COG1288	antiporter activity
CDL62_RS12485	COG2816	NAD+ diphosphatase activity
CDL62_RS12500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDL62_RS12505	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDL62_RS12505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDL62_RS12515	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDL62_RS12530	COG0009	L-threonylcarbamoyladenylate synthase
CDL62_RS12545	COG4124	Belongs to the glycosyl hydrolase 26 family
CDL62_RS12550	COG2996	Protein conserved in bacteria
CDL62_RS12555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDL62_RS12560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDL62_RS12580	COG4864	UPF0365 protein
CDL62_RS12595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDL62_RS12620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDL62_RS12630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDL62_RS12640	COG1408	metallophosphoesterase
CDL62_RS12645	COG0300	oxidoreductase activity
CDL62_RS12650	COG2815	serine threonine protein kinase
CDL62_RS12650	COG0515	serine threonine protein kinase
CDL62_RS12655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDL62_RS12665	COG0516	GMP reductase activity
CDL62_RS12665	COG0517	IMP dehydrogenase activity
CDL62_RS12670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDL62_RS12700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDL62_RS12705	COG0735	belongs to the Fur family
CDL62_RS12710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDL62_RS12760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDL62_RS12770	COG0811	peptide transport
CDL62_RS12775	COG0848	biopolymer transport protein
CDL62_RS12800	COG2409	Drug exporters of the RND superfamily
CDL62_RS12800	COG1033	growth of symbiont in host cell
CDL62_RS12815	COG4589	Belongs to the CDS family
CDL62_RS12830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDL62_RS12840	COG0300	oxidoreductase activity
CDL62_RS12900	COG4771	TonB-dependent receptor
CDL62_RS12925	COG0363	glucosamine-6-phosphate deaminase activity
CDL62_RS12935	COG4733	cellulase activity
CDL62_RS12940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CDL62_RS12945	COG2223	nitrite transmembrane transporter activity
CDL62_RS12955	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS12980	COG5505	Protein of unknown function (DUF819)
CDL62_RS12990	COG1380	Effector of murein hydrolase LrgA
CDL62_RS13010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDL62_RS13015	COG0352	thiamine-phosphate diphosphorylase activity
CDL62_RS13020	COG0351	phosphomethylpyrimidine kinase
CDL62_RS13025	COG0352	thiamine-phosphate diphosphorylase activity
CDL62_RS13030	COG2022	thiamine diphosphate biosynthetic process
CDL62_RS13035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDL62_RS13060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDL62_RS13065	COG4948	Mandelate Racemase Muconate Lactonizing
CDL62_RS13075	COG1575	Belongs to the MenA family. Type 1 subfamily
CDL62_RS13095	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDL62_RS13105	COG0824	Thioesterase
CDL62_RS13130	COG0488	(ABC) transporter
CDL62_RS13135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDL62_RS13140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDL62_RS13155	COG0463	Glycosyl transferase, family 2
CDL62_RS13185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDL62_RS13195	COG4771	TonB-dependent receptor
CDL62_RS13200	COG0561	phosphatase activity
CDL62_RS13205	COG1484	DNA-dependent DNA replication
CDL62_RS13225	COG0492	ferredoxin-NADP+ reductase activity
CDL62_RS13265	COG1215	transferase activity, transferring glycosyl groups
CDL62_RS13290	COG3876	Protein conserved in bacteria
CDL62_RS13305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS13315	COG1373	ATPase (AAA superfamily
CDL62_RS13330	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDL62_RS13345	COG3876	Protein conserved in bacteria
CDL62_RS13350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDL62_RS13355	COG0560	Phosphoserine phosphatase
CDL62_RS13355	COG3830	Belongs to the UPF0237 family
CDL62_RS13385	COG0673	inositol 2-dehydrogenase activity
CDL62_RS13390	COG0706	membrane insertase activity
CDL62_RS13395	COG0504	CTP synthase activity
CDL62_RS13410	COG0336	Belongs to the RNA methyltransferase TrmD family
CDL62_RS13420	COG0567	Dehydrogenase, E1 component
CDL62_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDL62_RS13430	COG2234	aminopeptidase activity
CDL62_RS13465	COG0745	RESPONSE REGULATOR receiver
CDL62_RS13470	COG2205	protein histidine kinase activity
CDL62_RS13470	COG0784	Response regulator, receiver
CDL62_RS13470	COG5002	protein histidine kinase activity
CDL62_RS13480	COG0156	8-amino-7-oxononanoate synthase activity
CDL62_RS13485	COG4772	TonB-dependent receptor
CDL62_RS13510	COG0497	DNA recombination
CDL62_RS13515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDL62_RS13530	COG0642	Histidine kinase
CDL62_RS13540	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDL62_RS13540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDL62_RS13540	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDL62_RS13540	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDL62_RS13545	COG0598	Magnesium transport protein CorA
CDL62_RS13555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDL62_RS13565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDL62_RS13580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDL62_RS13595	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDL62_RS13600	COG0792	nuclease activity
CDL62_RS13615	COG4213	ABC transporter substrate-binding protein
CDL62_RS13625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDL62_RS13635	COG2211	Major facilitator Superfamily
CDL62_RS13640	COG3459	Glycosyltransferase 36 associated
CDL62_RS13645	COG3291	Pkd domain containing protein
CDL62_RS13650	COG3250	beta-galactosidase activity
CDL62_RS13665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDL62_RS13670	COG3292	Two component regulator propeller
CDL62_RS13670	COG2205	protein histidine kinase activity
CDL62_RS13670	COG0745	RESPONSE REGULATOR receiver
CDL62_RS13690	COG3292	Two component regulator propeller
CDL62_RS13690	COG2205	protein histidine kinase activity
CDL62_RS13690	COG0745	RESPONSE REGULATOR receiver
CDL62_RS13710	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS13720	COG1629	transport
CDL62_RS13730	COG2373	Large extracellular alpha-helical protein
CDL62_RS13735	COG4953	penicillin-binding protein 1C
CDL62_RS13755	COG1640	4-alpha-glucanotransferase
CDL62_RS13780	COG2205	protein histidine kinase activity
CDL62_RS13780	COG0784	Response regulator, receiver
CDL62_RS13785	COG1716	ATPase activity
CDL62_RS13785	COG1131	(ABC) transporter
CDL62_RS13785	COG0842	Transport permease protein
CDL62_RS13790	COG0784	Response regulator, receiver
CDL62_RS13790	COG2205	protein histidine kinase activity
CDL62_RS13830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDL62_RS13835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDL62_RS13840	COG3279	Response regulator of the LytR AlgR family
CDL62_RS13855	COG1349	DNA-binding transcription factor activity
CDL62_RS13875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDL62_RS13890	COG1051	belongs to the nudix hydrolase family
CDL62_RS13915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDL62_RS13920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDL62_RS13920	COG0517	IMP dehydrogenase activity
CDL62_RS13930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDL62_RS13945	COG1846	Transcriptional regulator
CDL62_RS14060	COG1484	DNA-dependent DNA replication
CDL62_RS14065	COG4584	PFAM Integrase catalytic
CDL62_RS14080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDL62_RS14085	COG3292	Two component regulator propeller
CDL62_RS14085	COG2205	protein histidine kinase activity
CDL62_RS14085	COG0745	RESPONSE REGULATOR receiver
CDL62_RS14095	COG2755	lipolytic protein G-D-S-L family
CDL62_RS14100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDL62_RS14105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDL62_RS14115	COG1509	lysine 2,3-aminomutase activity
CDL62_RS14120	COG0339	signal peptide processing
CDL62_RS14130	COG0778	Nitroreductase
CDL62_RS14145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDL62_RS14160	COG0187	DNA topoisomerase II activity
CDL62_RS14175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDL62_RS14185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDL62_RS14190	COG0556	nucleotide-excision repair
CDL62_RS14200	COG1022	Amp-dependent synthetase and ligase
CDL62_RS14205	COG2186	Transcriptional regulator
CDL62_RS14215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDL62_RS14215	COG0047	phosphoribosylformylglycinamidine synthase activity
CDL62_RS14220	COG1063	alcohol dehydrogenase
CDL62_RS14250	COG0424	maF-like protein
CDL62_RS14255	COG4717	serine-type aminopeptidase activity
CDL62_RS14270	COG0671	phosphoesterase, PA-phosphatase related
CDL62_RS14280	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDL62_RS14315	COG1660	Displays ATPase and GTPase activities
CDL62_RS14320	COG2111	Na H antiporter
CDL62_RS14320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDL62_RS14325	COG2111	Na H antiporter
CDL62_RS14330	COG1006	Multisubunit Na H antiporter MnhC subunit
CDL62_RS14335	COG0651	ATP synthesis coupled electron transport
CDL62_RS14345	COG2212	antiporter activity
CDL62_RS14350	COG1320	monovalent cation:proton antiporter activity
CDL62_RS14355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDL62_RS14385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDL62_RS14395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDL62_RS14415	COG1132	(ABC) transporter
CDL62_RS14425	COG1030	water channel activity
CDL62_RS14440	COG0415	Belongs to the DNA photolyase family
CDL62_RS14485	COG0326	Molecular chaperone. Has ATPase activity
CDL62_RS14495	COG3457	Alanine racemase
CDL62_RS14500	COG0513	Belongs to the DEAD box helicase family
CDL62_RS14530	COG0596	Alpha beta hydrolase
CDL62_RS14550	COG4584	PFAM Integrase catalytic
CDL62_RS14550	COG2390	Transcriptional regulator
CDL62_RS14555	COG1484	DNA-dependent DNA replication
CDL62_RS14565	COG4584	PFAM Integrase catalytic
CDL62_RS14575	COG3385	transposase activity
CDL62_RS14635	COG3344	reverse transcriptase
CDL62_RS14645	COG3177	Filamentation induced by cAMP protein fic
CDL62_RS14680	COG4584	PFAM Integrase catalytic
CDL62_RS14690	COG1484	DNA-dependent DNA replication
CDL62_RS14715	COG0784	Response regulator, receiver
CDL62_RS14715	COG2205	protein histidine kinase activity
CDL62_RS14730	COG1401	restriction endodeoxyribonuclease activity
CDL62_RS14775	COG3344	reverse transcriptase
CDL62_RS14790	COG3344	reverse transcriptase
CDL62_RS14795	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CDL62_RS14795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDL62_RS14800	COG4584	PFAM Integrase catalytic
CDL62_RS14805	COG1484	DNA-dependent DNA replication
CDL62_RS14810	COG3344	reverse transcriptase
CDL62_RS14815	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDL62_RS14845	COG1373	ATPase (AAA superfamily
CDL62_RS14855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS14880	COG1484	DNA-dependent DNA replication
CDL62_RS14885	COG4584	PFAM Integrase catalytic
CDL62_RS14905	COG3344	reverse transcriptase
CDL62_RS14950	COG1373	ATPase (AAA superfamily
CDL62_RS15040	COG3344	reverse transcriptase
CDL62_RS15070	COG1484	DNA-dependent DNA replication
CDL62_RS15075	COG2390	Transcriptional regulator
CDL62_RS15075	COG4584	PFAM Integrase catalytic
CDL62_RS15095	COG4942	peptidase
CDL62_RS15150	COG0210	DNA helicase
CDL62_RS15155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDL62_RS15225	COG3344	reverse transcriptase
CDL62_RS15245	COG3344	reverse transcriptase
CDL62_RS15280	COG3344	reverse transcriptase
CDL62_RS15325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDL62_RS15650	COG0454	-acetyltransferase
CDL62_RS15655	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CDL62_RS15690	COG3586	endonuclease activity
CDL62_RS15815	COG4974	Belongs to the 'phage' integrase family
CDL62_RS15820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDL62_RS15820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDL62_RS15825	COG0693	protein deglycase activity
CDL62_RS15830	COG0791	NLP P60 protein
CDL62_RS15845	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDL62_RS15850	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDL62_RS15855	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDL62_RS15860	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDL62_RS15885	COG0577	efflux transmembrane transporter activity
CDL62_RS15895	COG1136	(ABC) transporter
CDL62_RS15920	COG4191	Histidine kinase
CDL62_RS15960	COG0714	Associated with various cellular activities
CDL62_RS15995	COG0110	maltose O-acetyltransferase activity
CDL62_RS16005	COG3206	protein involved in exopolysaccharide biosynthesis
CDL62_RS16005	COG0489	protein tyrosine kinase activity
CDL62_RS16015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDL62_RS16025	COG3206	protein involved in exopolysaccharide biosynthesis
CDL62_RS16025	COG0489	protein tyrosine kinase activity
CDL62_RS16030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDL62_RS16035	COG0534	Mate efflux family protein
CDL62_RS16075	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CDL62_RS16085	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDL62_RS16095	COG0511	ligase activity, forming carbon-carbon bonds
CDL62_RS16100	COG0439	Biotin carboxylase
CDL62_RS16105	COG1528	Iron-storage protein
CDL62_RS16110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDL62_RS16110	COG0116	Belongs to the methyltransferase superfamily
CDL62_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS16145	COG0583	DNA-binding transcription factor activity
CDL62_RS16165	COG0473	3-isopropylmalate dehydrogenase activity
CDL62_RS16180	COG0129	dihydroxy-acid dehydratase activity
CDL62_RS16210	COG2205	protein histidine kinase activity
CDL62_RS16230	COG1943	Transposase
CDL62_RS16245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDL62_RS16250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDL62_RS16255	COG1690	Belongs to the RtcB family
CDL62_RS16260	COG0501	Belongs to the peptidase M48B family
CDL62_RS16285	COG3437	response regulator, receiver
CDL62_RS16290	COG1278	Cold shock
CDL62_RS16295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDL62_RS16305	COG3426	butyrate kinase activity
CDL62_RS16310	COG0280	phosphate acetyltransferase
CDL62_RS16315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDL62_RS16320	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDL62_RS16325	COG0280	phosphate acetyltransferase
CDL62_RS16330	COG4771	TonB-dependent receptor
CDL62_RS16335	COG0738	Major facilitator superfamily
CDL62_RS16345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDL62_RS16360	COG1979	alcohol dehydrogenase
CDL62_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS16375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDL62_RS16385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDL62_RS16395	COG0105	UTP biosynthetic process
CDL62_RS16420	COG0004	ammonium transporteR
CDL62_RS16450	COG2885	chlorophyll binding
CDL62_RS16460	COG1629	transport
CDL62_RS16485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDL62_RS16490	COG0363	glucosamine-6-phosphate deaminase activity
CDL62_RS16495	COG1362	aminopeptidase activity
CDL62_RS16505	COG0540	Belongs to the ATCase OTCase family
CDL62_RS16510	COG1943	Transposase
CDL62_RS16515	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CDL62_RS16525	COG1074	ATP-dependent DNA helicase activity
CDL62_RS16530	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
CDL62_RS16535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDL62_RS16540	COG0457	Tetratricopeptide repeat
CDL62_RS16545	COG0542	response to heat
CDL62_RS16550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDL62_RS16560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDL62_RS16570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDL62_RS16585	COG0167	dihydroorotate dehydrogenase activity
CDL62_RS16590	COG0543	2 iron, 2 sulfur cluster binding
CDL62_RS16610	COG0022	dehydrogenase e1 component
CDL62_RS16615	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDL62_RS16620	COG3033	Beta-eliminating lyase
CDL62_RS16630	COG0538	isocitrate dehydrogenase activity
CDL62_RS16640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDL62_RS16645	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDL62_RS16660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDL62_RS16665	COG0552	protein localization to endoplasmic reticulum
CDL62_RS16675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDL62_RS16680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDL62_RS16690	COG0501	Belongs to the peptidase M48B family
CDL62_RS16695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDL62_RS16700	COG0653	protein targeting
CDL62_RS16745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDL62_RS16765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDL62_RS16785	COG1739	Uncharacterized protein family UPF0029
CDL62_RS16790	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDL62_RS16810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDL62_RS16820	COG0702	epimerase
CDL62_RS16845	COG3693	PFAM glycoside hydrolase, family 10
CDL62_RS16850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDL62_RS16855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDL62_RS16860	COG0673	inositol 2-dehydrogenase activity
CDL62_RS16875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDL62_RS16890	COG2843	Capsule synthesis protein
CDL62_RS16905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDL62_RS16920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDL62_RS16930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDL62_RS16945	COG3956	TIGRFAM MazG family protein
CDL62_RS16965	COG0793	Belongs to the peptidase S41A family
CDL62_RS16965	COG4946	Tricorn protease homolog
CDL62_RS17035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CDL62_RS17060	COG3385	transposase activity
CDL62_RS17135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDL62_RS17145	COG0101	tRNA pseudouridine synthase activity
CDL62_RS17160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDL62_RS17175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDL62_RS17185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDL62_RS17195	COG0673	inositol 2-dehydrogenase activity
CDL62_RS17200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDL62_RS17205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDL62_RS17210	COG0784	Response regulator, receiver
CDL62_RS17210	COG2205	protein histidine kinase activity
CDL62_RS17225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDL62_RS17230	COG1569	PIN domain
CDL62_RS17240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDL62_RS17245	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CDL62_RS17250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDL62_RS17255	COG1418	mRNA catabolic process
CDL62_RS17270	COG1032	radical SAM domain protein
CDL62_RS17280	COG1242	4 iron, 4 sulfur cluster binding
CDL62_RS17295	COG0189	ligase activity
CDL62_RS17305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDL62_RS17310	COG1959	2 iron, 2 sulfur cluster binding
CDL62_RS17320	COG0463	Glycosyl transferase, family 2
CDL62_RS17320	COG1216	Glycosyl transferase, family 2
CDL62_RS17350	COG0167	dihydroorotate dehydrogenase activity
CDL62_RS17355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDL62_RS17365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDL62_RS17370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CDL62_RS17375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDL62_RS17385	COG1366	Belongs to the anti-sigma-factor antagonist family
CDL62_RS17390	COG0542	response to heat
CDL62_RS17410	COG0842	Transport permease protein
CDL62_RS17410	COG1131	(ABC) transporter
CDL62_RS17410	COG1716	ATPase activity
CDL62_RS17425	COG1045	serine acetyltransferase
CDL62_RS17440	COG3409	Peptidoglycan-binding domain 1 protein
CDL62_RS17440	COG0793	Belongs to the peptidase S41A family
CDL62_RS17445	COG0519	Catalyzes the synthesis of GMP from XMP
CDL62_RS17445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDL62_RS17450	COG1234	tRNA 3'-trailer cleavage
CDL62_RS17460	COG0539	negative regulation of cytoplasmic translation
CDL62_RS17490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDL62_RS17495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDL62_RS17510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDL62_RS17510	COG0116	Belongs to the methyltransferase superfamily
CDL62_RS17535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDL62_RS17540	COG4974	Belongs to the 'phage' integrase family
CDL62_RS17550	COG1090	epimerase
CDL62_RS17555	COG1196	nuclear chromosome segregation
CDL62_RS17555	COG3264	Mechanosensitive ion channel
CDL62_RS17565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDL62_RS17580	COG0149	triose-phosphate isomerase activity
CDL62_RS17585	COG2264	protein methyltransferase activity
CDL62_RS17600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDL62_RS17605	COG0602	queuosine metabolic process
CDL62_RS17610	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDL62_RS17610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDL62_RS17620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDL62_RS17635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDL62_RS17645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDL62_RS17655	COG0018	arginyl-trna synthetase
CDL62_RS17660	COG2205	protein histidine kinase activity
CDL62_RS17660	COG0784	Response regulator, receiver
CDL62_RS17680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDL62_RS17695	COG0656	L-ascorbic acid biosynthetic process
CDL62_RS17700	COG3530	Putative quorum-sensing-regulated virulence factor
CDL62_RS17705	COG2382	esterase
CDL62_RS17705	COG3507	Belongs to the glycosyl hydrolase 43 family
CDL62_RS17705	COG3693	PFAM glycoside hydrolase, family 10
CDL62_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
CDL62_RS17730	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS17770	COG1506	peptidase
CDL62_RS17770	COG0823	Involved in the tonB-independent uptake of proteins
CDL62_RS17785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDL62_RS17785	COG1918	ferrous iron import across plasma membrane
CDL62_RS17800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDL62_RS17810	COG1862	Preprotein translocase
CDL62_RS17820	COG0531	amino acid
CDL62_RS17830	COG0237	dephospho-CoA kinase activity
CDL62_RS17835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDL62_RS17840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDL62_RS17845	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDL62_RS17850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDL62_RS17865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDL62_RS17870	COG0681	Belongs to the peptidase S26 family
CDL62_RS17875	COG0681	Belongs to the peptidase S26 family
CDL62_RS17895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CDL62_RS17900	COG0335	large ribosomal subunit rRNA binding
CDL62_RS17920	COG2205	protein histidine kinase activity
CDL62_RS17925	COG2133	pyrroloquinoline quinone binding
CDL62_RS17940	COG0519	Catalyzes the synthesis of GMP from XMP
CDL62_RS17940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDL62_RS17960	COG0702	epimerase
CDL62_RS17980	COG0826	peptidase U32
CDL62_RS17985	COG4206	TonB-dependent receptor
CDL62_RS18025	COG4999	Histidine kinase
CDL62_RS18025	COG3850	Histidine kinase
CDL62_RS18025	COG3437	response regulator, receiver
CDL62_RS18025	COG2205	protein histidine kinase activity
CDL62_RS18030	COG1301	dicarboxylic acid transport
CDL62_RS18035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDL62_RS18040	COG1047	Peptidyl-prolyl cis-trans
CDL62_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
CDL62_RS18060	COG3279	Response regulator of the LytR AlgR family
CDL62_RS18075	COG2502	aspartate--ammonia ligase
CDL62_RS18080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDL62_RS18090	COG1674	ftsk spoiiie
CDL62_RS18120	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CDL62_RS18125	COG5016	pyruvate
CDL62_RS18125	COG0511	ligase activity, forming carbon-carbon bonds
CDL62_RS18135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDL62_RS18140	COG0346	lactoylglutathione lyase activity
CDL62_RS18145	COG2884	Cell division ATP-binding protein ftsE
CDL62_RS18165	COG0426	domain, Protein
CDL62_RS18175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDL62_RS18275	COG0110	maltose O-acetyltransferase activity
CDL62_RS18290	COG0463	Glycosyl transferase, family 2
CDL62_RS18290	COG1216	Glycosyl transferase, family 2
CDL62_RS18300	COG1215	transferase activity, transferring glycosyl groups
CDL62_RS18310	COG1442	glycosyl transferase family 8
CDL62_RS18310	COG1216	Glycosyl transferase, family 2
CDL62_RS18325	COG2852	Protein conserved in bacteria
CDL62_RS18355	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS18360	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS18400	COG0438	transferase activity, transferring glycosyl groups
CDL62_RS18415	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CDL62_RS18420	COG0386	Belongs to the glutathione peroxidase family
CDL62_RS18440	COG0488	(ABC) transporter
CDL62_RS18445	COG3942	CHAP domain
CDL62_RS18445	COG1388	LysM domain