locus-tag	class	description
KWG61_RS00020	COG3250	beta-galactosidase activity
KWG61_RS00085	COG3250	beta-galactosidase activity
KWG61_RS00120	COG4122	O-methyltransferase activity
KWG61_RS00130	COG0203	ribosomal protein L17
KWG61_RS00135	COG0202	RNA polymerase activity
KWG61_RS00145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KWG61_RS00150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KWG61_RS00170	COG0563	adenylate kinase activity
KWG61_RS00195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KWG61_RS00260	COG0089	rRNA binding
KWG61_RS00265	COG0088	Forms part of the polypeptide exit tunnel
KWG61_RS00275	COG0051	transcription antitermination factor activity, RNA binding
KWG61_RS00280	COG3328	transposase activity
KWG61_RS00295	COG0531	amino acid
KWG61_RS00300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KWG61_RS00305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KWG61_RS00315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KWG61_RS00320	COG3842	ATPase activity
KWG61_RS00350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KWG61_RS00380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KWG61_RS00425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KWG61_RS00440	COG0765	amino acid transport
KWG61_RS00460	COG3830	Belongs to the UPF0237 family
KWG61_RS00470	COG0280	phosphate acetyltransferase
KWG61_RS00495	COG0285	dihydrofolate synthase activity
KWG61_RS00510	COG3409	Peptidoglycan-binding domain 1 protein
KWG61_RS00510	COG0793	Belongs to the peptidase S41A family
KWG61_RS00515	COG0598	Magnesium transport protein CorA
KWG61_RS00580	COG0419	ATPase involved in DNA repair
KWG61_RS00595	COG1592	Rubrerythrin
KWG61_RS00690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KWG61_RS00730	COG2226	methyltransferase
KWG61_RS00735	COG0799	negative regulation of ribosome biogenesis
KWG61_RS00740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KWG61_RS00750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KWG61_RS00770	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KWG61_RS00775	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KWG61_RS00780	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KWG61_RS00810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KWG61_RS00820	COG0537	adenosine 5'-monophosphoramidase activity
KWG61_RS00825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KWG61_RS00870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KWG61_RS00880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KWG61_RS00890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KWG61_RS00900	COG2188	Transcriptional regulator
KWG61_RS00905	COG1131	(ABC) transporter
KWG61_RS00915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KWG61_RS00915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KWG61_RS00920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KWG61_RS00930	COG3591	Belongs to the peptidase S1B family
KWG61_RS00960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KWG61_RS00990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KWG61_RS01005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KWG61_RS01010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KWG61_RS01020	COG1328	CTP reductase activity
KWG61_RS01040	COG1918	ferrous iron import across plasma membrane
KWG61_RS01040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KWG61_RS01050	COG2738	Putative neutral zinc metallopeptidase
KWG61_RS01060	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KWG61_RS01120	COG3591	Belongs to the peptidase S1B family
KWG61_RS01150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KWG61_RS01180	COG0534	Mate efflux family protein
KWG61_RS01185	COG0436	Aminotransferase
KWG61_RS01200	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KWG61_RS01205	COG4166	transmembrane transport
KWG61_RS01210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KWG61_RS01215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KWG61_RS01255	COG1214	PFAM Peptidase M22, glycoprotease
KWG61_RS01260	COG0802	atpase or kinase
KWG61_RS01315	COG0747	negative chemotaxis
KWG61_RS01335	COG0477	Major facilitator Superfamily
KWG61_RS01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS01370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01375	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KWG61_RS01375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS01380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KWG61_RS01390	COG1105	Belongs to the carbohydrate kinase PfkB family
KWG61_RS01430	COG0167	dihydroorotate dehydrogenase activity
KWG61_RS01435	COG0543	2 iron, 2 sulfur cluster binding
KWG61_RS01445	COG0505	Belongs to the CarA family
KWG61_RS01450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KWG61_RS01455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KWG61_RS01460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KWG61_RS01485	COG4535	Mg2 and Co2 transporter CorC
KWG61_RS01525	COG0617	tRNA 3'-terminal CCA addition
KWG61_RS01540	COG0312	modulator of DNA gyrase
KWG61_RS01545	COG0312	modulator of DNA gyrase
KWG61_RS01550	COG0312	modulator of DNA gyrase
KWG61_RS01620	COG3250	beta-galactosidase activity
KWG61_RS01625	COG3250	beta-galactosidase activity
KWG61_RS01710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KWG61_RS01715	COG3481	metal-dependent phosphohydrolase, HD sub domain
KWG61_RS01735	COG0438	transferase activity, transferring glycosyl groups
KWG61_RS01755	COG0438	transferase activity, transferring glycosyl groups
KWG61_RS01855	COG2608	mercury ion transmembrane transporter activity
KWG61_RS01860	COG2217	Heavy metal translocating P-type atpase
KWG61_RS01880	COG1177	transmembrane transport
KWG61_RS01885	COG1177	transmembrane transport
KWG61_RS01890	COG1176	ABC-type spermidine putrescine transport system, permease component I
KWG61_RS01925	COG2367	Beta-lactamase
KWG61_RS01980	COG2252	PERMEase
KWG61_RS01985	COG1074	ATP-dependent DNA helicase activity
KWG61_RS02015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KWG61_RS02025	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KWG61_RS02035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KWG61_RS02070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KWG61_RS02075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KWG61_RS02090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KWG61_RS02095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KWG61_RS02110	COG5002	protein histidine kinase activity
KWG61_RS02145	COG1696	Membrane protein involved in D-alanine export
KWG61_RS02180	COG4821	SIS domain
KWG61_RS02185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KWG61_RS02190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KWG61_RS02220	COG0024	Methionine aminopeptidase
KWG61_RS02225	COG2890	protein-(glutamine-N5) methyltransferase activity
KWG61_RS02230	COG2890	protein-(glutamine-N5) methyltransferase activity
KWG61_RS02245	COG0084	hydrolase, TatD family'
KWG61_RS02255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KWG61_RS02260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KWG61_RS02285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KWG61_RS02290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KWG61_RS02300	COG0562	UDP-galactopyranose mutase
KWG61_RS02320	COG1475	DNA binding
KWG61_RS02325	COG1192	Involved in chromosome partitioning
KWG61_RS02335	COG0357	Ribosomal RNA small subunit methyltransferase G
KWG61_RS02345	COG3343	RNA polymerase activity
KWG61_RS02350	COG0018	arginyl-trna synthetase
KWG61_RS02355	COG0018	arginyl-trna synthetase
KWG61_RS02370	COG1078	dGTPase activity
KWG61_RS02380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KWG61_RS02385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KWG61_RS02390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KWG61_RS02430	COG0594	ribonuclease P activity
KWG61_RS02435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KWG61_RS02460	COG2501	S4 domain
KWG61_RS02465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KWG61_RS02500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KWG61_RS02550	COG0772	Belongs to the SEDS family
KWG61_RS02570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KWG61_RS02575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KWG61_RS02585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KWG61_RS02595	COG1253	flavin adenine dinucleotide binding
KWG61_RS02620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KWG61_RS02650	COG1774	PSP1 C-terminal conserved region
KWG61_RS02670	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KWG61_RS02685	COG0726	polysaccharide deacetylase
KWG61_RS02695	COG0151	Belongs to the GarS family
KWG61_RS02745	COG1396	sequence-specific DNA binding
KWG61_RS02785	COG0493	'glutamate synthase
KWG61_RS02800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KWG61_RS02845	COG1307	EDD domain protein, DegV family
KWG61_RS02880	COG3118	belongs to the thioredoxin family
KWG61_RS02885	COG0791	NLP P60 protein
KWG61_RS02885	COG0741	lytic transglycosylase activity
KWG61_RS02910	COG3118	belongs to the thioredoxin family
KWG61_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
KWG61_RS02945	COG1555	photosystem II stabilization
KWG61_RS02990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KWG61_RS03015	COG2176	DNA-directed DNA polymerase activity
KWG61_RS03040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KWG61_RS03065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KWG61_RS03070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KWG61_RS03075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KWG61_RS03085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KWG61_RS03140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KWG61_RS03145	COG1733	regulation of RNA biosynthetic process
KWG61_RS03230	COG0484	heat shock protein binding
KWG61_RS03235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KWG61_RS03260	COG1732	Glycine betaine
KWG61_RS03280	COG1609	Transcriptional regulator
KWG61_RS03320	COG0058	SHG alpha-glucan phosphorylase activity
KWG61_RS03325	COG0058	SHG alpha-glucan phosphorylase activity
KWG61_RS03345	COG3842	ATPase activity
KWG61_RS03355	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KWG61_RS03385	COG0463	Glycosyl transferase, family 2
KWG61_RS03390	COG0463	Glycosyl transferase, family 2
KWG61_RS03395	COG1442	glycosyl transferase family 8
KWG61_RS03395	COG1216	Glycosyl transferase, family 2
KWG61_RS03450	COG1473	amidohydrolase
KWG61_RS03460	COG0019	diaminopimelate decarboxylase activity
KWG61_RS03465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KWG61_RS03470	COG0454	-acetyltransferase
KWG61_RS03515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS03515	COG2190	(PTS) system
KWG61_RS03515	COG1263	PTS System
KWG61_RS03520	COG2190	(PTS) system
KWG61_RS03520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS03520	COG1263	PTS System
KWG61_RS03530	COG1609	Transcriptional regulator
KWG61_RS03545	COG0165	Argininosuccinate lyase
KWG61_RS03560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KWG61_RS03565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KWG61_RS03580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KWG61_RS03585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KWG61_RS03595	COG1396	sequence-specific DNA binding
KWG61_RS03635	COG4608	Belongs to the ABC transporter superfamily
KWG61_RS03645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KWG61_RS03650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KWG61_RS03655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KWG61_RS03660	COG0601	transmembrane transport
KWG61_RS03665	COG4166	transmembrane transport
KWG61_RS03735	COG1263	PTS System
KWG61_RS03735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS03745	COG1621	beta-fructofuranosidase activity
KWG61_RS03750	COG1621	beta-fructofuranosidase activity
KWG61_RS03760	COG1609	Transcriptional regulator
KWG61_RS03925	COG2205	protein histidine kinase activity
KWG61_RS03940	COG0742	ribosomal rna small subunit methyltransferase
KWG61_RS03955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KWG61_RS03960	COG0768	penicillin binding
KWG61_RS03970	COG2001	Belongs to the MraZ family
KWG61_RS03985	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KWG61_RS03995	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KWG61_RS04005	COG1518	maintenance of DNA repeat elements
KWG61_RS04010	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KWG61_RS04075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KWG61_RS04115	COG2357	RelA SpoT domain protein
KWG61_RS04135	COG0561	phosphatase activity
KWG61_RS04155	COG1194	a g-specific adenine glycosylase
KWG61_RS04160	COG0561	phosphatase activity
KWG61_RS04180	COG0653	protein targeting
KWG61_RS04265	COG3142	Participates in the control of copper homeostasis
KWG61_RS04310	COG0613	PHP domain protein
KWG61_RS04360	COG0577	efflux transmembrane transporter activity
KWG61_RS04370	COG0698	ribose 5-phosphate isomerase
KWG61_RS04385	COG1979	alcohol dehydrogenase
KWG61_RS04405	COG1979	alcohol dehydrogenase
KWG61_RS04425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KWG61_RS04425	COG3408	Glycogen debranching enzyme
KWG61_RS04450	COG3328	transposase activity
KWG61_RS04550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KWG61_RS04590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KWG61_RS04625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KWG61_RS04675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS04675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS04685	COG1879	ABC-type sugar transport system periplasmic component
KWG61_RS04695	COG4211	Belongs to the binding-protein-dependent transport system permease family
KWG61_RS04720	COG0252	asparaginase activity
KWG61_RS04740	COG1051	belongs to the nudix hydrolase family
KWG61_RS04745	COG1321	iron dependent repressor
KWG61_RS04750	COG0826	peptidase U32
KWG61_RS04765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KWG61_RS04770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KWG61_RS04785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KWG61_RS04840	COG2003	Belongs to the UPF0758 family
KWG61_RS04855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS04855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS04870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KWG61_RS04875	COG0237	dephospho-CoA kinase activity
KWG61_RS04970	COG0581	inorganic phosphate transmembrane transporter activity
KWG61_RS04980	COG0573	inorganic phosphate transmembrane transporter activity
KWG61_RS05075	COG0823	Involved in the tonB-independent uptake of proteins
KWG61_RS05075	COG1506	peptidase
KWG61_RS05075	COG4946	Tricorn protease homolog
KWG61_RS05125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KWG61_RS05130	COG0561	phosphatase activity
KWG61_RS05165	COG2205	protein histidine kinase activity
KWG61_RS05165	COG2770	Histidine kinase
KWG61_RS05245	COG3250	beta-galactosidase activity
KWG61_RS05270	COG0640	Transcriptional regulator
KWG61_RS05280	COG2217	Heavy metal translocating P-type atpase
KWG61_RS05300	COG2183	response to ionizing radiation
KWG61_RS05315	COG2183	response to ionizing radiation
KWG61_RS05325	COG2183	response to ionizing radiation
KWG61_RS05330	COG2183	response to ionizing radiation
KWG61_RS05370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KWG61_RS05390	COG0612	Peptidase, M16
KWG61_RS05430	COG0301	tRNA thio-modification
KWG61_RS05435	COG0301	tRNA thio-modification
KWG61_RS05455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KWG61_RS05570	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KWG61_RS05645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KWG61_RS05670	COG3250	beta-galactosidase activity
KWG61_RS05675	COG3250	beta-galactosidase activity
KWG61_RS05730	COG2011	ABC-type metal ion transport system permease component
KWG61_RS05775	COG1876	peptidase activity
KWG61_RS05800	COG4821	SIS domain
KWG61_RS05805	COG0210	DNA helicase
KWG61_RS05965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KWG61_RS06025	COG0668	transmembrane transport
KWG61_RS06130	COG0656	L-ascorbic acid biosynthetic process
KWG61_RS06140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KWG61_RS06150	COG3064	Membrane
KWG61_RS06150	COG3583	domain protein
KWG61_RS06150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KWG61_RS06155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KWG61_RS06165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS06165	COG0072	phenylalanine-tRNA ligase activity
KWG61_RS06170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS06170	COG0072	phenylalanine-tRNA ligase activity
KWG61_RS06185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS06185	COG0072	phenylalanine-tRNA ligase activity
KWG61_RS06250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KWG61_RS06270	COG0335	large ribosomal subunit rRNA binding
KWG61_RS06275	COG1234	tRNA 3'-trailer cleavage
KWG61_RS06280	COG0681	Belongs to the peptidase S26 family
KWG61_RS06285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KWG61_RS06305	COG4974	Belongs to the 'phage' integrase family
KWG61_RS06320	COG2246	polysaccharide biosynthetic process
KWG61_RS06325	COG4821	SIS domain
KWG61_RS06350	COG0561	phosphatase activity
KWG61_RS06370	COG0789	Transcriptional regulator
KWG61_RS06415	COG4555	ABC transporter
KWG61_RS06425	COG0233	cytoplasmic translational termination
KWG61_RS06435	COG0575	Belongs to the CDS family
KWG61_RS06455	COG1196	nuclear chromosome segregation
KWG61_RS06460	COG1196	nuclear chromosome segregation
KWG61_RS06465	COG1196	nuclear chromosome segregation
KWG61_RS06495	COG0587	DNA-directed DNA polymerase activity
KWG61_RS06500	COG0587	DNA-directed DNA polymerase activity
KWG61_RS06515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KWG61_RS06520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KWG61_RS06530	COG5434	Belongs to the glycosyl hydrolase 28 family
KWG61_RS06540	COG4886	Leucine-rich repeat (LRR) protein
KWG61_RS06550	COG0463	Glycosyl transferase, family 2
KWG61_RS06555	COG0708	Exodeoxyribonuclease III
KWG61_RS06565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KWG61_RS06570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KWG61_RS06580	COG0632	four-way junction helicase activity
KWG61_RS06585	COG2255	four-way junction helicase activity
KWG61_RS06595	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KWG61_RS06595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KWG61_RS06605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KWG61_RS06620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KWG61_RS06625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KWG61_RS06665	COG3561	AntA/AntB antirepressor
KWG61_RS06890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS06890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS06980	COG1472	Belongs to the glycosyl hydrolase 3 family
KWG61_RS07005	COG1323	Belongs to the UPF0348 family
KWG61_RS07015	COG1399	metal-binding, possibly nucleic acid-binding protein
KWG61_RS07020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KWG61_RS07035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KWG61_RS07040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KWG61_RS07095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KWG61_RS07105	COG3763	UPF0154 protein
KWG61_RS07205	COG1484	DNA-dependent DNA replication
KWG61_RS07235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KWG61_RS07235	COG4499	WXG100 protein secretion system (Wss), protein YukC
KWG61_RS07285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KWG61_RS07290	COG0564	pseudouridine synthase activity
KWG61_RS07310	COG1193	negative regulation of DNA recombination
KWG61_RS07320	COG0322	excinuclease ABC activity
KWG61_RS07325	COG1876	peptidase activity
KWG61_RS07355	COG0544	peptidyl-prolyl cis-trans isomerase activity
KWG61_RS07395	COG0544	peptidyl-prolyl cis-trans isomerase activity
KWG61_RS07430	COG1063	alcohol dehydrogenase
KWG61_RS07435	COG1105	Belongs to the carbohydrate kinase PfkB family
KWG61_RS07440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS07450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS07450	COG3711	transcriptional antiterminator
KWG61_RS07460	COG2213	PTS system mannitol-specific
KWG61_RS07460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS07485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KWG61_RS07485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KWG61_RS07490	COG1215	transferase activity, transferring glycosyl groups
KWG61_RS07505	COG0438	transferase activity, transferring glycosyl groups
KWG61_RS07505	COG1216	Glycosyl transferase, family 2
KWG61_RS07560	COG2264	protein methyltransferase activity
KWG61_RS07615	COG1151	hydroxylamine reductase activity
KWG61_RS07640	COG2033	superoxide reductase activity
KWG61_RS07670	COG4120	Belongs to the binding-protein-dependent transport system permease family
KWG61_RS07685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KWG61_RS07690	COG0297	glycogen (starch) synthase activity
KWG61_RS07700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS07705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KWG61_RS07710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KWG61_RS07785	COG3655	Transcriptional regulator
KWG61_RS07845	COG1959	2 iron, 2 sulfur cluster binding
KWG61_RS07910	COG0205	6-phosphofructokinase activity
KWG61_RS07915	COG0205	6-phosphofructokinase activity
KWG61_RS07970	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KWG61_RS07975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KWG61_RS07995	COG0250	Participates in transcription elongation, termination and antitermination
KWG61_RS08000	COG1609	Transcriptional regulator
KWG61_RS08010	COG1609	Transcriptional regulator
KWG61_RS08015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KWG61_RS08020	COG0647	UMP catabolic process
KWG61_RS08035	COG0557	exoribonuclease II activity
KWG61_RS08040	COG0557	exoribonuclease II activity
KWG61_RS08045	COG0557	exoribonuclease II activity
KWG61_RS08050	COG3591	Belongs to the peptidase S1B family
KWG61_RS08070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KWG61_RS08080	COG1132	(ABC) transporter
KWG61_RS08085	COG1132	(ABC) transporter
KWG61_RS08160	COG3842	ATPase activity
KWG61_RS08225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KWG61_RS08255	COG2801	Transposase and inactivated derivatives
KWG61_RS08290	COG3250	beta-galactosidase activity
KWG61_RS08310	COG0826	peptidase U32
KWG61_RS08385	COG0534	Mate efflux family protein
KWG61_RS08665	COG3409	Peptidoglycan-binding domain 1 protein
KWG61_RS08665	COG5632	N-Acetylmuramoyl-L-alanine amidase
KWG61_RS08685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KWG61_RS08690	COG0768	penicillin binding
KWG61_RS08700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KWG61_RS08710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KWG61_RS08815	COG4279	zinc finger
KWG61_RS08820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KWG61_RS08825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KWG61_RS08855	COG0039	L-malate dehydrogenase activity
KWG61_RS08860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KWG61_RS08870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KWG61_RS08940	COG1242	4 iron, 4 sulfur cluster binding
KWG61_RS08945	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KWG61_RS08965	COG1799	cell septum assembly
KWG61_RS08995	COG1773	rubredoxin
KWG61_RS09005	COG1477	protein flavinylation
KWG61_RS09025	COG4658	electron transport chain
KWG61_RS09040	COG4660	Part of a membrane complex involved in electron transport
KWG61_RS09105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KWG61_RS09155	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KWG61_RS09165	COG0366	Alpha amylase catalytic
KWG61_RS09170	COG2190	(PTS) system
KWG61_RS09170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS09170	COG1263	PTS System
KWG61_RS09175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS09175	COG1263	PTS System
KWG61_RS09185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KWG61_RS09195	COG0513	Belongs to the DEAD box helicase family
KWG61_RS09245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KWG61_RS09250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KWG61_RS09295	COG1609	Transcriptional regulator
KWG61_RS09325	COG0515	serine threonine protein kinase
KWG61_RS09325	COG2815	serine threonine protein kinase
KWG61_RS09335	COG1162	GTPase activity
KWG61_RS09345	COG1564	THIamine pyrophosphokinase
KWG61_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
KWG61_RS09410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KWG61_RS09415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KWG61_RS09510	COG0494	nUDIX hydrolase
KWG61_RS09575	COG1595	DNA-templated transcription, initiation
KWG61_RS09580	COG0493	'glutamate synthase
KWG61_RS09585	COG0067	glutamate synthase
KWG61_RS09585	COG0069	glutamate synthase activity
KWG61_RS09585	COG0070	glutamate synthase
KWG61_RS09590	COG0067	glutamate synthase
KWG61_RS09590	COG0069	glutamate synthase activity
KWG61_RS09590	COG0070	glutamate synthase
KWG61_RS09595	COG0070	glutamate synthase
KWG61_RS09595	COG0067	glutamate synthase
KWG61_RS09595	COG0069	glutamate synthase activity
KWG61_RS09600	COG0069	glutamate synthase activity
KWG61_RS09600	COG0067	glutamate synthase
KWG61_RS09600	COG0070	glutamate synthase
KWG61_RS09615	COG1263	PTS System
KWG61_RS09615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS09615	COG2190	(PTS) system
KWG61_RS09620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS09620	COG1263	PTS System
KWG61_RS09625	COG1263	PTS System
KWG61_RS09625	COG2190	(PTS) system
KWG61_RS09625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS09630	COG2723	6-phospho-beta-galactosidase activity
KWG61_RS09660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KWG61_RS09705	COG0493	'glutamate synthase
KWG61_RS09705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KWG61_RS09715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KWG61_RS09750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KWG61_RS09755	COG0776	regulation of translation
KWG61_RS09760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KWG61_RS09770	COG0765	amino acid transport
KWG61_RS09865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KWG61_RS09905	COG1373	ATPase (AAA superfamily
KWG61_RS09930	COG3436	PFAM IS66 Orf2 family protein
KWG61_RS10000	COG1748	Saccharopine dehydrogenase
KWG61_RS10005	COG0561	phosphatase activity
KWG61_RS10065	COG0668	transmembrane transport
KWG61_RS10110	COG1447	Phosphotransferase system cellobiose-specific component IIA
KWG61_RS10120	COG2188	Transcriptional regulator
KWG61_RS10160	COG0489	protein tyrosine kinase activity
KWG61_RS10170	COG4974	Belongs to the 'phage' integrase family
KWG61_RS10190	COG0497	DNA recombination
KWG61_RS10235	COG1570	exodeoxyribonuclease VII activity
KWG61_RS10240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KWG61_RS10250	COG0196	riboflavin kinase activity
KWG61_RS10260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KWG61_RS10265	COG0037	tRNA processing
KWG61_RS10275	COG1393	Belongs to the ArsC family
KWG61_RS10285	COG3885	ferrous iron binding
KWG61_RS10285	COG2078	PFAM AMMECR1 domain protein
KWG61_RS10300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KWG61_RS10310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KWG61_RS10325	COG1187	pseudouridine synthase activity
KWG61_RS10335	COG0860	N-Acetylmuramoyl-L-alanine amidase
KWG61_RS10340	COG0494	nUDIX hydrolase
KWG61_RS10345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KWG61_RS10355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KWG61_RS10405	COG1024	Enoyl-CoA hydratase
KWG61_RS10425	COG2086	electron transfer activity
KWG61_RS10435	COG0183	Belongs to the thiolase family
KWG61_RS10520	COG0195	Participates in both transcription termination and antitermination
KWG61_RS10525	COG0195	Participates in both transcription termination and antitermination
KWG61_RS10530	COG0779	Required for maturation of 30S ribosomal subunits
KWG61_RS10535	COG0194	GDP metabolic process
KWG61_RS10560	COG3385	transposase activity
KWG61_RS10590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KWG61_RS10595	COG1609	Transcriptional regulator
KWG61_RS10630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KWG61_RS10650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KWG61_RS10685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KWG61_RS10690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KWG61_RS10700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KWG61_RS10730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KWG61_RS10735	COG3906	Belongs to the UPF0473 family
KWG61_RS10755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KWG61_RS10790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KWG61_RS10790	COG1648	precorrin-2 dehydrogenase activity
KWG61_RS10805	COG1120	ATPase activity
KWG61_RS10910	COG1523	belongs to the glycosyl hydrolase 13 family
KWG61_RS10920	COG0114	fumarate hydratase activity
KWG61_RS10940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KWG61_RS10945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KWG61_RS10985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KWG61_RS10995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KWG61_RS11230	COG0582	viral genome integration into host DNA
KWG61_RS11295	COG2205	protein histidine kinase activity
KWG61_RS11305	COG2211	Major facilitator Superfamily
KWG61_RS11320	COG3250	beta-galactosidase activity
KWG61_RS11355	COG5002	protein histidine kinase activity
KWG61_RS11370	COG0745	RESPONSE REGULATOR receiver
KWG61_RS11375	COG0745	RESPONSE REGULATOR receiver
KWG61_RS11380	COG1283	sodium-dependent phosphate transmembrane transporter activity
KWG61_RS11390	COG0800	Aldolase
KWG61_RS11395	COG1904	glucuronate isomerase
KWG61_RS11400	COG0789	Transcriptional regulator
KWG61_RS11430	COG0246	Mannitol dehydrogenase
KWG61_RS11440	COG0246	Mannitol dehydrogenase
KWG61_RS11465	COG0561	phosphatase activity
KWG61_RS11485	COG2239	Acts as a magnesium transporter
KWG61_RS11505	COG2239	Acts as a magnesium transporter
KWG61_RS11540	COG1247	-acetyltransferase
KWG61_RS11560	COG1132	(ABC) transporter
KWG61_RS11575	COG1132	(ABC) transporter
KWG61_RS11580	COG0124	histidyl-tRNA synthetase
KWG61_RS11620	COG0343	queuine tRNA-ribosyltransferase activity
KWG61_RS11800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KWG61_RS11810	COG0138	bifunctional purine biosynthesis protein purh
KWG61_RS11815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KWG61_RS11825	COG0047	phosphoribosylformylglycinamidine synthase activity
KWG61_RS11835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KWG61_RS11845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KWG61_RS11850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KWG61_RS11860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KWG61_RS11875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KWG61_RS11890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KWG61_RS12000	COG0778	Nitroreductase
KWG61_RS12020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KWG61_RS12060	COG0205	6-phosphofructokinase activity
KWG61_RS12095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KWG61_RS12100	COG0561	phosphatase activity
KWG61_RS12150	COG2205	protein histidine kinase activity
KWG61_RS12185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KWG61_RS12190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KWG61_RS12195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KWG61_RS12205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KWG61_RS12220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KWG61_RS12225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KWG61_RS12235	COG0124	histidyl-tRNA synthetase
KWG61_RS12240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KWG61_RS12265	COG0538	isocitrate dehydrogenase activity
KWG61_RS12295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KWG61_RS12315	COG1940	carbohydrate kinase activity
KWG61_RS12345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KWG61_RS12350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KWG61_RS12360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KWG61_RS12385	COG0363	glucosamine-6-phosphate deaminase activity
KWG61_RS12415	COG3715	PTS system
KWG61_RS12420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KWG61_RS12455	COG2222	sugar isomerase
KWG61_RS12465	COG0560	Phosphoserine phosphatase
KWG61_RS12505	COG1227	inorganic diphosphatase activity
KWG61_RS12535	COG0424	maF-like protein
KWG61_RS12580	COG0083	homoserine kinase activity
KWG61_RS12585	COG0083	homoserine kinase activity
KWG61_RS12595	COG0460	homoserine dehydrogenase
KWG61_RS12605	COG0527	aspartate kinase activity
KWG61_RS12610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KWG61_RS12670	COG5012	cobalamin binding
KWG61_RS12680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KWG61_RS12680	COG0646	methionine synthase
KWG61_RS12725	COG1278	Cold shock
KWG61_RS12765	COG0719	Fe-S assembly protein
KWG61_RS12775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KWG61_RS12930	COG0483	inositol monophosphate 1-phosphatase activity
KWG61_RS13225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KWG61_RS13240	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KWG61_RS13240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KWG61_RS13300	COG2873	o-acetylhomoserine
KWG61_RS13305	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KWG61_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
KWG61_RS13335	COG0488	(ABC) transporter
KWG61_RS13340	COG0488	(ABC) transporter
KWG61_RS13425	COG3436	PFAM IS66 Orf2 family protein
KWG61_RS13480	COG1481	regulation of sporulation
KWG61_RS13485	COG1481	regulation of sporulation
KWG61_RS13490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KWG61_RS13505	COG0569	domain protein
KWG61_RS13510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KWG61_RS13515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KWG61_RS13585	COG1131	(ABC) transporter
KWG61_RS13595	COG1725	Transcriptional regulator
KWG61_RS13615	COG1126	abc transporter atp-binding protein
KWG61_RS13620	COG0765	amino acid transport
KWG61_RS13705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KWG61_RS13755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KWG61_RS13810	COG1316	TRANSCRIPTIONal
KWG61_RS13850	COG0446	pyridine nucleotide-disulphide oxidoreductase
KWG61_RS13865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KWG61_RS13895	COG0426	domain, Protein
KWG61_RS13895	COG1773	rubredoxin
KWG61_RS14040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KWG61_RS14105	COG1131	(ABC) transporter
KWG61_RS14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KWG61_RS14125	COG0740	serine-type endopeptidase activity
KWG61_RS14165	COG0515	serine threonine protein kinase
KWG61_RS14165	COG0457	Tetratricopeptide repeat
KWG61_RS14220	COG3716	PTS system mannose fructose sorbose family IID component
KWG61_RS14225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KWG61_RS14235	COG0366	Alpha amylase catalytic
KWG61_RS14240	COG1737	Transcriptional regulator
KWG61_RS14260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KWG61_RS14350	COG1484	DNA-dependent DNA replication
KWG61_RS14415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS14415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS14530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KWG61_RS14540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KWG61_RS14565	COG0356	it plays a direct role in the translocation of protons across the membrane
KWG61_RS14585	COG1234	tRNA 3'-trailer cleavage
KWG61_RS14595	COG0359	binds to the 23S rRNA
KWG61_RS14600	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KWG61_RS14635	COG0464	growth
KWG61_RS14650	COG0360	Binds together with S18 to 16S ribosomal RNA
KWG61_RS14685	COG1307	EDD domain protein, DegV family
KWG61_RS14705	COG0577	efflux transmembrane transporter activity
KWG61_RS14770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KWG61_RS14775	COG3177	Filamentation induced by cAMP protein fic
KWG61_RS14780	COG1393	Belongs to the ArsC family
KWG61_RS14790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KWG61_RS14840	COG0488	(ABC) transporter
KWG61_RS14850	COG1132	(ABC) transporter
KWG61_RS14855	COG1132	(ABC) transporter
KWG61_RS14860	COG1132	(ABC) transporter
KWG61_RS14865	COG1132	(ABC) transporter
KWG61_RS14875	COG0202	RNA polymerase activity
KWG61_RS14885	COG1077	Cell shape determining protein MreB Mrl
KWG61_RS14930	COG0745	RESPONSE REGULATOR receiver
KWG61_RS14935	COG0745	RESPONSE REGULATOR receiver
KWG61_RS14985	COG1368	sulfuric ester hydrolase activity
KWG61_RS14990	COG0251	oxidation-reduction process
KWG61_RS15000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KWG61_RS15040	COG0440	acetolactate synthase activity
KWG61_RS15045	COG0028	Belongs to the TPP enzyme family
KWG61_RS15130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KWG61_RS15135	COG0569	domain protein
KWG61_RS15165	COG0366	Alpha amylase catalytic
KWG61_RS15180	COG0411	ABC transporter
KWG61_RS15235	COG1994	Peptidase M50
KWG61_RS15245	COG0012	GTP binding
KWG61_RS15275	COG0778	Nitroreductase
KWG61_RS15335	COG2176	DNA-directed DNA polymerase activity
KWG61_RS15340	COG2176	DNA-directed DNA polymerase activity
KWG61_RS15345	COG2176	DNA-directed DNA polymerase activity
KWG61_RS15350	COG2176	DNA-directed DNA polymerase activity
KWG61_RS15370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KWG61_RS15375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KWG61_RS15420	COG1696	Membrane protein involved in D-alanine export
KWG61_RS15440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KWG61_RS15445	COG2720	vancomycin resistance protein
KWG61_RS15470	COG3599	regulation of cell shape
KWG61_RS15480	COG4499	WXG100 protein secretion system (Wss), protein YukC
KWG61_RS15480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KWG61_RS15510	COG0530	calcium, potassium:sodium antiporter activity
KWG61_RS15515	COG1971	Probably functions as a manganese efflux pump
KWG61_RS15545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KWG61_RS15565	COG1484	DNA-dependent DNA replication
KWG61_RS15590	COG0745	RESPONSE REGULATOR receiver
KWG61_RS15605	COG0101	tRNA pseudouridine synthase activity
KWG61_RS15610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KWG61_RS15645	COG3250	beta-galactosidase activity
KWG61_RS15715	COG1105	Belongs to the carbohydrate kinase PfkB family
KWG61_RS15750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KWG61_RS15785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KWG61_RS15810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KWG61_RS15820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KWG61_RS15830	COG1116	anion transmembrane transporter activity
KWG61_RS15835	COG3842	ATPase activity
KWG61_RS15870	COG1496	oxidoreductase activity
KWG61_RS15885	COG0058	SHG alpha-glucan phosphorylase activity
KWG61_RS15895	COG1114	Component of the transport system for branched-chain amino acids
KWG61_RS15905	COG1114	Component of the transport system for branched-chain amino acids
KWG61_RS15995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS15995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KWG61_RS16020	COG2183	response to ionizing radiation
KWG61_RS16065	COG0436	Aminotransferase
KWG61_RS16070	COG0436	Aminotransferase
KWG61_RS16080	COG0072	phenylalanine-tRNA ligase activity
KWG61_RS16080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS16085	COG0072	phenylalanine-tRNA ligase activity
KWG61_RS16085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KWG61_RS16120	COG0708	Exodeoxyribonuclease III
KWG61_RS16150	COG1323	Belongs to the UPF0348 family
KWG61_RS16155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KWG61_RS16160	COG3328	transposase activity
KWG61_RS16165	COG3328	transposase activity
KWG61_RS16180	COG0443	Heat shock 70 kDa protein
KWG61_RS16240	COG1760	l-serine dehydratase
KWG61_RS16245	COG1760	l-serine dehydratase
KWG61_RS16255	COG0358	DNA primase activity
KWG61_RS16260	COG0366	Alpha amylase catalytic
KWG61_RS16270	COG0628	permease
KWG61_RS16285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KWG61_RS16290	COG2723	6-phospho-beta-galactosidase activity
KWG61_RS16300	COG0174	glutamine synthetase
KWG61_RS16305	COG3250	beta-galactosidase activity
KWG61_RS16340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KWG61_RS16345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KWG61_RS16350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KWG61_RS16355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KWG61_RS16400	COG1312	Catalyzes the dehydration of D-mannonate
KWG61_RS16415	COG0343	queuine tRNA-ribosyltransferase activity
KWG61_RS16420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KWG61_RS16425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KWG61_RS16450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KWG61_RS16455	COG0588	phosphoglycerate mutase activity
KWG61_RS16480	COG0372	Belongs to the citrate synthase family
KWG61_RS16485	COG0372	Belongs to the citrate synthase family
KWG61_RS16505	COG2873	o-acetylhomoserine
KWG61_RS16570	COG0366	Alpha amylase catalytic
KWG61_RS16575	COG0366	Alpha amylase catalytic
KWG61_RS16605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KWG61_RS16625	COG3328	transposase activity
KWG61_RS16630	COG3328	transposase activity
KWG61_RS16635	COG0772	Belongs to the SEDS family
KWG61_RS16640	COG0561	phosphatase activity