locus-tag	class	description
ALVIN_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALVIN_RS00015	COG0592	DNA-directed DNA polymerase activity
ALVIN_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALVIN_RS00045	COG1136	(ABC) transporter
ALVIN_RS00050	COG0071	Belongs to the small heat shock protein (HSP20) family
ALVIN_RS00140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALVIN_RS00155	COG0187	DNA topoisomerase II activity
ALVIN_RS00165	COG0070	glutamate synthase
ALVIN_RS00165	COG0069	glutamate synthase activity
ALVIN_RS00165	COG0067	glutamate synthase
ALVIN_RS00180	COG0357	Ribosomal RNA small subunit methyltransferase G
ALVIN_RS00185	COG1192	Involved in chromosome partitioning
ALVIN_RS00190	COG1475	DNA binding
ALVIN_RS00195	COG3312	ion transport
ALVIN_RS00200	COG0356	it plays a direct role in the translocation of protons across the membrane
ALVIN_RS00210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ALVIN_RS00215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ALVIN_RS00220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ALVIN_RS00230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ALVIN_RS00235	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ALVIN_RS00240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ALVIN_RS00245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ALVIN_RS00280	COG1490	D-aminoacyl-tRNA deacylase activity
ALVIN_RS00285	COG0596	Alpha beta hydrolase
ALVIN_RS00290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ALVIN_RS00305	COG3243	poly(R)-hydroxyalkanoic acid synthase
ALVIN_RS00315	COG0183	Belongs to the thiolase family
ALVIN_RS00320	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ALVIN_RS00330	COG1028	Short-chain dehydrogenase reductase Sdr
ALVIN_RS00335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ALVIN_RS00340	COG0723	plastoquinol--plastocyanin reductase activity
ALVIN_RS00345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALVIN_RS00350	COG2857	Cytochrome c1
ALVIN_RS00355	COG0625	glutathione transferase activity
ALVIN_RS00360	COG2969	positive regulation of protein catabolic process
ALVIN_RS00400	COG1238	metal cluster binding
ALVIN_RS00405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALVIN_RS00420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ALVIN_RS00430	COG3012	SEC-C Motif Domain Protein
ALVIN_RS00445	COG3258	Cytochrome c
ALVIN_RS00475	COG2186	Transcriptional regulator
ALVIN_RS00500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ALVIN_RS00505	COG0352	thiamine-phosphate diphosphorylase activity
ALVIN_RS00510	COG0351	phosphomethylpyrimidine kinase
ALVIN_RS00525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ALVIN_RS00530	COG0316	Belongs to the HesB IscA family
ALVIN_RS00540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ALVIN_RS00595	COG0494	nUDIX hydrolase
ALVIN_RS00600	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ALVIN_RS00605	COG0277	FAD linked oxidase domain protein
ALVIN_RS00610	COG2823	Periplasmic or secreted lipoprotein
ALVIN_RS00615	COG0792	nuclease activity
ALVIN_RS00625	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ALVIN_RS00630	COG2001	Belongs to the MraZ family
ALVIN_RS00635	COG0275	rRNA processing
ALVIN_RS00640	COG3116	cell division
ALVIN_RS00650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ALVIN_RS00655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALVIN_RS00660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ALVIN_RS00665	COG0772	Belongs to the SEDS family
ALVIN_RS00670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ALVIN_RS00680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ALVIN_RS00685	COG1181	Belongs to the D-alanine--D-alanine ligase family
ALVIN_RS00690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ALVIN_RS00705	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ALVIN_RS00715	COG4942	peptidase
ALVIN_RS00720	COG0653	protein targeting
ALVIN_RS00725	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ALVIN_RS00730	COG0494	nUDIX hydrolase
ALVIN_RS00755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ALVIN_RS00760	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ALVIN_RS00770	COG0217	transcriptional regulatory protein
ALVIN_RS00775	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ALVIN_RS00780	COG0632	four-way junction helicase activity
ALVIN_RS00790	COG0277	FAD linked oxidase domain protein
ALVIN_RS00795	COG0247	lactate metabolic process
ALVIN_RS00805	COG0237	dephospho-CoA kinase activity
ALVIN_RS00820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALVIN_RS00830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ALVIN_RS00850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALVIN_RS00855	COG0134	indole-3-glycerol-phosphate synthase activity
ALVIN_RS00860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALVIN_RS00865	COG1765	OsmC-like protein
ALVIN_RS00870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ALVIN_RS00885	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ALVIN_RS00890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ALVIN_RS00900	COG1002	Type II restriction enzyme, methylase subunits
ALVIN_RS00905	COG1061	Type III restriction enzyme res subunit
ALVIN_RS00910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ALVIN_RS00920	COG0840	transmembrane signaling receptor activity
ALVIN_RS00920	COG0840	transmembrane signaling receptor activity
ALVIN_RS00925	COG0737	Belongs to the 5'-nucleotidase family
ALVIN_RS00930	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ALVIN_RS00935	COG0511	ligase activity, forming carbon-carbon bonds
ALVIN_RS00935	COG5016	pyruvate
ALVIN_RS00945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ALVIN_RS00950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ALVIN_RS00955	COG2363	Small membrane protein
ALVIN_RS00960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ALVIN_RS00965	COG0784	Response regulator, receiver
ALVIN_RS00965	COG0643	Histidine kinase
ALVIN_RS00965	COG2198	Histidine kinase
ALVIN_RS00970	COG0840	transmembrane signaling receptor activity
ALVIN_RS00990	COG0189	ligase activity
ALVIN_RS01005	COG1678	Uncharacterized ACR, COG1678
ALVIN_RS01010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ALVIN_RS01020	COG0540	Belongs to the ATCase OTCase family
ALVIN_RS01070	COG1216	Glycosyl transferase, family 2
ALVIN_RS01070	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS01135	COG3293	Transposase
ALVIN_RS01175	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS01180	COG5002	protein histidine kinase activity
ALVIN_RS01190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS01205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ALVIN_RS01215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALVIN_RS01230	COG1301	dicarboxylic acid transport
ALVIN_RS01245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ALVIN_RS01255	COG2336	PFAM SpoVT AbrB
ALVIN_RS01260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ALVIN_RS01260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALVIN_RS01265	COG3100	YcgL domain-containing protein
ALVIN_RS01265	COG0561	phosphatase activity
ALVIN_RS01270	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS01280	COG1058	Belongs to the CinA family
ALVIN_RS01280	COG1546	Belongs to the CinA family
ALVIN_RS01305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ALVIN_RS01320	COG1793	dna ligase
ALVIN_RS01325	COG0167	dihydroorotate dehydrogenase activity
ALVIN_RS01330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ALVIN_RS01330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ALVIN_RS01330	COG1013	pyruvate-flavodoxin oxidoreductase activity
ALVIN_RS01330	COG0674	pyruvate-flavodoxin oxidoreductase activity
ALVIN_RS01335	COG0456	acetyltransferase
ALVIN_RS01355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ALVIN_RS01360	COG0546	phosphoglycolate phosphatase activity
ALVIN_RS01370	COG0667	Aldo Keto reductase
ALVIN_RS01390	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS01395	COG2205	protein histidine kinase activity
ALVIN_RS01400	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALVIN_RS01405	COG3876	Protein conserved in bacteria
ALVIN_RS01410	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ALVIN_RS01420	COG0724	RNA recognition motif
ALVIN_RS01430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ALVIN_RS01430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ALVIN_RS01435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ALVIN_RS01440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALVIN_RS01440	COG0515	serine threonine protein kinase
ALVIN_RS01465	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALVIN_RS01470	COG0567	Dehydrogenase, E1 component
ALVIN_RS01500	COG0633	Ferredoxin
ALVIN_RS01520	COG0724	RNA recognition motif
ALVIN_RS01525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ALVIN_RS01530	COG0339	signal peptide processing
ALVIN_RS01545	COG3706	GGDEF domain
ALVIN_RS01560	COG4251	negative regulation of phosphorylation
ALVIN_RS01565	COG0191	fructose-bisphosphate aldolase activity
ALVIN_RS01570	COG0469	pyruvate kinase activity
ALVIN_RS01575	COG0126	phosphoglycerate kinase activity
ALVIN_RS01580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ALVIN_RS01585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ALVIN_RS01595	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ALVIN_RS01600	COG2226	methyltransferase
ALVIN_RS01605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ALVIN_RS01610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ALVIN_RS01615	COG2211	Major facilitator Superfamily
ALVIN_RS01630	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ALVIN_RS01640	COG1477	protein flavinylation
ALVIN_RS01655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS01660	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS01665	COG4115	mRNA cleavage
ALVIN_RS01670	COG2161	toxin-antitoxin pair type II binding
ALVIN_RS01675	COG0650	Formate hydrogenlyase subunit 4
ALVIN_RS01680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALVIN_RS01680	COG2111	Na H antiporter
ALVIN_RS01690	COG0596	Alpha beta hydrolase
ALVIN_RS01690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALVIN_RS01690	COG2226	methyltransferase
ALVIN_RS01695	COG2995	paraquat-inducible protein a
ALVIN_RS01700	COG3008	intermembrane lipid transfer
ALVIN_RS01710	COG0004	ammonium transporteR
ALVIN_RS01750	COG0840	transmembrane signaling receptor activity
ALVIN_RS01770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALVIN_RS01775	COG1573	uracil-dna glycosylase
ALVIN_RS01790	COG0556	nucleotide-excision repair
ALVIN_RS01795	COG0436	Aminotransferase
ALVIN_RS01805	COG0840	transmembrane signaling receptor activity
ALVIN_RS01815	COG0826	peptidase U32
ALVIN_RS01820	COG2983	Belongs to the UPF0260 family
ALVIN_RS01830	COG4974	Belongs to the 'phage' integrase family
ALVIN_RS01835	COG1666	GTP binding
ALVIN_RS01840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ALVIN_RS01845	COG0631	protein serine/threonine phosphatase activity
ALVIN_RS01850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ALVIN_RS01865	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS01880	COG0573	inorganic phosphate transmembrane transporter activity
ALVIN_RS01890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ALVIN_RS01895	COG0704	Plays a role in the regulation of phosphate uptake
ALVIN_RS01905	COG0741	lytic transglycosylase activity
ALVIN_RS01905	COG1388	LysM domain
ALVIN_RS01915	COG0328	RNA-DNA hybrid ribonuclease activity
ALVIN_RS01920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALVIN_RS01925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALVIN_RS01935	COG0504	CTP synthase activity
ALVIN_RS01940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ALVIN_RS01945	COG0148	phosphopyruvate hydratase activity
ALVIN_RS01950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ALVIN_RS01955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ALVIN_RS01960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ALVIN_RS01965	COG0585	pseudouridine synthase activity
ALVIN_RS01970	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS02015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ALVIN_RS02035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ALVIN_RS02040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALVIN_RS02045	COG2171	N-acyltransferase activity
ALVIN_RS02050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ALVIN_RS02055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ALVIN_RS02060	COG2894	cell division
ALVIN_RS02065	COG0850	regulation of cytokinetic process
ALVIN_RS02070	COG0537	adenosine 5'-monophosphoramidase activity
ALVIN_RS02075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ALVIN_RS02080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ALVIN_RS02085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ALVIN_RS02110	COG5002	protein histidine kinase activity
ALVIN_RS02110	COG2205	protein histidine kinase activity
ALVIN_RS02110	COG0784	Response regulator, receiver
ALVIN_RS02120	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ALVIN_RS02125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ALVIN_RS02140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALVIN_RS02155	COG3550	peptidyl-serine autophosphorylation
ALVIN_RS02165	COG4251	negative regulation of phosphorylation
ALVIN_RS02170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALVIN_RS02175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ALVIN_RS02180	COG0215	cysteine-tRNA ligase activity
ALVIN_RS02210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALVIN_RS02215	COG4636	protein conserved in cyanobacteria
ALVIN_RS02270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALVIN_RS02285	COG0363	glucosamine-6-phosphate deaminase activity
ALVIN_RS02295	COG4067	protein conserved in archaea
ALVIN_RS02295	COG0189	ligase activity
ALVIN_RS02300	COG2308	Evidence 4 Homologs of previously reported genes of
ALVIN_RS02315	COG1295	ribonuclease BN
ALVIN_RS02325	COG0587	DNA-directed DNA polymerase activity
ALVIN_RS02365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALVIN_RS02370	COG2379	hydroxypyruvate reductase
ALVIN_RS02380	COG1214	PFAM Peptidase M22, glycoprotease
ALVIN_RS02390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ALVIN_RS02400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ALVIN_RS02405	COG4988	ABC transporter
ALVIN_RS02410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ALVIN_RS02420	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALVIN_RS02435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALVIN_RS02440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ALVIN_RS02445	COG1472	Belongs to the glycosyl hydrolase 3 family
ALVIN_RS02450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALVIN_RS02460	COG5007	Belongs to the BolA IbaG family
ALVIN_RS02465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ALVIN_RS02470	COG0165	Argininosuccinate lyase
ALVIN_RS02475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ALVIN_RS02500	COG0195	Participates in both transcription termination and antitermination
ALVIN_RS02505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ALVIN_RS02510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ALVIN_RS02515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ALVIN_RS02520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ALVIN_RS02525	COG1185	polyribonucleotide nucleotidyltransferase activity
ALVIN_RS02530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALVIN_RS02535	COG2308	Evidence 4 Homologs of previously reported genes of
ALVIN_RS02545	COG0864	Transcriptional regulator
ALVIN_RS02575	COG0310	cobalt ion transport
ALVIN_RS02595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALVIN_RS02600	COG2027	D-alanyl-D-alanine carboxypeptidase
ALVIN_RS02605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ALVIN_RS02610	COG2226	methyltransferase
ALVIN_RS02620	COG0156	8-amino-7-oxononanoate synthase activity
ALVIN_RS02625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALVIN_RS02630	COG1040	competence protein
ALVIN_RS02680	COG3293	Transposase
ALVIN_RS02700	COG2307	Protein conserved in bacteria
ALVIN_RS02700	COG2308	Evidence 4 Homologs of previously reported genes of
ALVIN_RS02710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ALVIN_RS02720	COG0688	phosphatidylethanolamine metabolic process
ALVIN_RS02730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ALVIN_RS02740	COG1121	(ABC) transporter
ALVIN_RS02745	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ALVIN_RS02785	COG0514	ATP-dependent DNA helicase (RecQ)
ALVIN_RS02790	COG3954	Phosphoribulokinase
ALVIN_RS02800	COG4660	Part of a membrane complex involved in electron transport
ALVIN_RS02805	COG4659	FMN binding
ALVIN_RS02815	COG0659	secondary active sulfate transmembrane transporter activity
ALVIN_RS02825	COG2878	Part of a membrane complex involved in electron transport
ALVIN_RS02830	COG4657	Part of a membrane complex involved in electron transport
ALVIN_RS02840	COG0798	PFAM Bile acid sodium symporter
ALVIN_RS02850	COG0659	secondary active sulfate transmembrane transporter activity
ALVIN_RS02855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ALVIN_RS02860	COG3263	regulation of cellular component size
ALVIN_RS02865	COG1028	Short-chain dehydrogenase reductase Sdr
ALVIN_RS02875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALVIN_RS02900	COG2161	toxin-antitoxin pair type II binding
ALVIN_RS02910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS02950	COG0840	transmembrane signaling receptor activity
ALVIN_RS02970	COG2373	Large extracellular alpha-helical protein
ALVIN_RS02975	COG4953	penicillin-binding protein 1C
ALVIN_RS02980	COG4771	TonB-dependent receptor
ALVIN_RS02990	COG3706	GGDEF domain
ALVIN_RS02995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ALVIN_RS03010	COG1011	Hydrolase
ALVIN_RS03020	COG0857	belongs to the CobB CobQ family
ALVIN_RS03020	COG0280	phosphate acetyltransferase
ALVIN_RS03025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ALVIN_RS03035	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ALVIN_RS03060	COG4178	(ABC) transporter
ALVIN_RS03070	COG3459	Glycosyltransferase 36 associated
ALVIN_RS03085	COG0768	penicillin binding
ALVIN_RS03095	COG1575	Belongs to the MenA family. Type 1 subfamily
ALVIN_RS03105	COG4456	Virulence-associated protein
ALVIN_RS03110	COG1487	ribonuclease activity
ALVIN_RS03115	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ALVIN_RS03120	COG1169	isochorismate synthase
ALVIN_RS03125	COG0596	Alpha beta hydrolase
ALVIN_RS03125	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALVIN_RS03140	COG0488	(ABC) transporter
ALVIN_RS03155	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ALVIN_RS03160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ALVIN_RS03165	COG0795	lipopolysaccharide-transporting ATPase activity
ALVIN_RS03175	COG4191	Histidine kinase
ALVIN_RS03180	COG4566	intracellular signal transduction
ALVIN_RS03215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALVIN_RS03220	COG1518	maintenance of DNA repeat elements
ALVIN_RS03240	COG1857	crispr-associated protein
ALVIN_RS03255	COG1203	CRISPR-associated helicase, Cas3
ALVIN_RS03290	COG0835	chemotaxis
ALVIN_RS03290	COG0784	Response regulator, receiver
ALVIN_RS03295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALVIN_RS03300	COG1815	bacterial-type flagellum-dependent cell motility
ALVIN_RS03305	COG1558	bacterial-type flagellum-dependent cell motility
ALVIN_RS03310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ALVIN_RS03325	COG4786	Flagellar basal body rod
ALVIN_RS03335	COG1706	bacterial-type flagellum-dependent cell motility
ALVIN_RS03350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ALVIN_RS03360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALVIN_RS03410	COG4771	TonB-dependent receptor
ALVIN_RS03420	COG2146	nitrite reductase [NAD(P)H] activity
ALVIN_RS03425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ALVIN_RS03440	COG0825	malonyl-CoA metabolic process
ALVIN_RS03445	COG0037	tRNA processing
ALVIN_RS03455	COG3118	belongs to the thioredoxin family
ALVIN_RS03460	COG3118	belongs to the thioredoxin family
ALVIN_RS03465	COG4566	intracellular signal transduction
ALVIN_RS03475	COG4251	negative regulation of phosphorylation
ALVIN_RS03480	COG4251	negative regulation of phosphorylation
ALVIN_RS03485	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ALVIN_RS03525	COG0505	Belongs to the CarA family
ALVIN_RS03530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ALVIN_RS03535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ALVIN_RS03555	COG0300	oxidoreductase activity
ALVIN_RS03570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ALVIN_RS03575	COG0494	nUDIX hydrolase
ALVIN_RS03580	COG1132	(ABC) transporter
ALVIN_RS03595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ALVIN_RS03600	COG1530	ribonuclease E activity
ALVIN_RS03610	COG0546	phosphoglycolate phosphatase activity
ALVIN_RS03615	COG0616	signal peptide processing
ALVIN_RS03640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ALVIN_RS03645	COG4106	trans-aconitate 2-methyltransferase activity
ALVIN_RS03650	COG0500	methyltransferase
ALVIN_RS03665	COG0719	Fe-S assembly protein
ALVIN_RS03670	COG0396	ATPase activity
ALVIN_RS03675	COG0719	Fe-S assembly protein
ALVIN_RS03680	COG2151	metal-sulfur cluster biosynthetic enzyme
ALVIN_RS03720	COG4566	intracellular signal transduction
ALVIN_RS03750	COG3885	ferrous iron binding
ALVIN_RS03750	COG2078	PFAM AMMECR1 domain protein
ALVIN_RS03755	COG1355	regulation of microtubule-based process
ALVIN_RS03765	COG1196	nuclear chromosome segregation
ALVIN_RS03765	COG0739	heme binding
ALVIN_RS03765	COG0741	lytic transglycosylase activity
ALVIN_RS03775	COG0730	response to heat
ALVIN_RS03785	COG2226	methyltransferase
ALVIN_RS03790	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ALVIN_RS03795	COG0596	Alpha beta hydrolase
ALVIN_RS03800	COG1469	GTP cyclohydrolase I activity
ALVIN_RS03805	COG0142	geranyltranstransferase activity
ALVIN_RS03810	COG1722	exodeoxyribonuclease VII activity
ALVIN_RS03815	COG0187	DNA topoisomerase II activity
ALVIN_RS03835	COG0268	Binds directly to 16S ribosomal RNA
ALVIN_RS03840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ALVIN_RS03855	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ALVIN_RS03860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALVIN_RS03865	COG1388	LysM domain
ALVIN_RS03865	COG4942	peptidase
ALVIN_RS03875	COG3278	Belongs to the heme-copper respiratory oxidase family
ALVIN_RS03895	COG0348	domain, Protein
ALVIN_RS03905	COG2217	Heavy metal translocating P-type atpase
ALVIN_RS03915	COG0840	transmembrane signaling receptor activity
ALVIN_RS03930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALVIN_RS03930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ALVIN_RS03955	COG3830	Belongs to the UPF0237 family
ALVIN_RS03960	COG0242	peptide deformylase activity
ALVIN_RS03965	COG0793	Belongs to the peptidase S41A family
ALVIN_RS03970	COG2918	glutathione biosynthetic process
ALVIN_RS03975	COG0248	Ppx GppA phosphatase
ALVIN_RS03985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALVIN_RS03990	COG0508	dehydrogenase complex catalyzes the overall conversion of
ALVIN_RS04025	COG0343	queuine tRNA-ribosyltransferase activity
ALVIN_RS04030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ALVIN_RS04035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALVIN_RS04040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ALVIN_RS04045	COG3178	'Phosphotransferase
ALVIN_RS04070	COG0151	Belongs to the GarS family
ALVIN_RS04075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALVIN_RS04080	COG0138	bifunctional purine biosynthesis protein purh
ALVIN_RS04090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALVIN_RS04110	COG3344	reverse transcriptase
ALVIN_RS04125	COG2264	protein methyltransferase activity
ALVIN_RS04150	COG0628	permease
ALVIN_RS04175	COG0668	transmembrane transport
ALVIN_RS04185	COG4591	ABC-type transport system involved in lipoprotein release permease component
ALVIN_RS04200	COG2333	competence protein COMEC
ALVIN_RS04200	COG0658	competence protein
ALVIN_RS04205	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ALVIN_RS04210	COG0406	alpha-ribazole phosphatase activity
ALVIN_RS04215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ALVIN_RS04220	COG4206	TonB-dependent receptor
ALVIN_RS04230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ALVIN_RS04240	COG3028	Belongs to the UPF0307 family
ALVIN_RS04250	COG2304	oxidoreductase activity
ALVIN_RS04260	COG1902	pentaerythritol trinitrate reductase activity
ALVIN_RS04280	COG1959	2 iron, 2 sulfur cluster binding
ALVIN_RS04285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ALVIN_RS04295	COG1560	Kdo2-lipid A biosynthetic process
ALVIN_RS04320	COG4149	molybdate abc transporter
ALVIN_RS04345	COG0848	biopolymer transport protein
ALVIN_RS04350	COG0811	peptide transport
ALVIN_RS04360	COG4772	TonB-dependent receptor
ALVIN_RS04375	COG3287	FIST C domain
ALVIN_RS04375	COG2199	diguanylate cyclase activity
ALVIN_RS04375	COG2200	EAL domain
ALVIN_RS04405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ALVIN_RS04410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ALVIN_RS04420	COG0582	viral genome integration into host DNA
ALVIN_RS04495	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
ALVIN_RS04510	COG0501	Belongs to the peptidase M48B family
ALVIN_RS04515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ALVIN_RS04520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALVIN_RS04525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ALVIN_RS04530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ALVIN_RS04535	COG0509	glycine decarboxylation via glycine cleavage system
ALVIN_RS04540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ALVIN_RS04550	COG0495	leucyl-tRNA aminoacylation
ALVIN_RS04555	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ALVIN_RS04570	COG0012	GTP binding
ALVIN_RS04585	COG0668	transmembrane transport
ALVIN_RS04600	COG4109	DRTGG domain
ALVIN_RS04630	COG2201	protein-glutamate methylesterase activity
ALVIN_RS04660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ALVIN_RS04680	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS04685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS04690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALVIN_RS04700	COG0028	Belongs to the TPP enzyme family
ALVIN_RS04710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ALVIN_RS04715	COG0824	Thioesterase
ALVIN_RS04735	COG0823	Involved in the tonB-independent uptake of proteins
ALVIN_RS04760	COG0271	Belongs to the BolA IbaG family
ALVIN_RS04775	COG1414	Transcriptional regulator
ALVIN_RS04790	COG1131	(ABC) transporter
ALVIN_RS04805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALVIN_RS04815	COG3706	GGDEF domain
ALVIN_RS04820	COG0840	transmembrane signaling receptor activity
ALVIN_RS04825	COG0784	Response regulator, receiver
ALVIN_RS04825	COG2205	protein histidine kinase activity
ALVIN_RS04825	COG5002	protein histidine kinase activity
ALVIN_RS04840	COG4555	ABC transporter
ALVIN_RS04850	COG0604	alcohol dehydrogenase
ALVIN_RS04865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ALVIN_RS04875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ALVIN_RS04885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ALVIN_RS04895	COG0776	regulation of translation
ALVIN_RS04910	COG0429	hydrolase of the alpha beta-hydrolase fold
ALVIN_RS04920	COG4682	membrane
ALVIN_RS04925	COG1397	ADP-ribosylglycohydrolase
ALVIN_RS04960	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ALVIN_RS04980	COG1902	pentaerythritol trinitrate reductase activity
ALVIN_RS04995	COG0450	alkyl hydroperoxide reductase
ALVIN_RS05020	COG2824	Alkylphosphonate utilization operon protein PhnA
ALVIN_RS05035	COG0811	peptide transport
ALVIN_RS05040	COG0848	biopolymer transport protein
ALVIN_RS05045	COG1132	(ABC) transporter
ALVIN_RS05050	COG1663	tetraacyldisaccharide 4'-kinase activity
ALVIN_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
ALVIN_RS05070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ALVIN_RS05075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ALVIN_RS05080	COG0308	aminopeptidase N
ALVIN_RS05130	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ALVIN_RS05140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALVIN_RS05155	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALVIN_RS05165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ALVIN_RS05205	COG1136	(ABC) transporter
ALVIN_RS05235	COG2205	protein histidine kinase activity
ALVIN_RS05235	COG2198	Histidine kinase
ALVIN_RS05235	COG0784	Response regulator, receiver
ALVIN_RS05240	COG4585	Histidine kinase
ALVIN_RS05245	COG2197	response regulator
ALVIN_RS05260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALVIN_RS05265	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ALVIN_RS05270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ALVIN_RS05275	COG1242	4 iron, 4 sulfur cluster binding
ALVIN_RS05280	COG0826	peptidase U32
ALVIN_RS05285	COG0826	peptidase U32
ALVIN_RS05300	COG0840	transmembrane signaling receptor activity
ALVIN_RS05330	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ALVIN_RS05350	COG3038	cytochrome b561
ALVIN_RS05365	COG1053	succinate dehydrogenase
ALVIN_RS05395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ALVIN_RS05400	COG0163	prenyltransferase activity
ALVIN_RS05405	COG1444	tRNA N-acetyltransferase activity
ALVIN_RS05410	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALVIN_RS05415	COG2863	cytochrome
ALVIN_RS05420	COG0666	response to abiotic stimulus
ALVIN_RS05425	COG3005	denitrification pathway
ALVIN_RS05430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ALVIN_RS05445	COG2137	regulation of response to DNA damage stimulus
ALVIN_RS05450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ALVIN_RS05460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ALVIN_RS05470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ALVIN_RS05490	COG0730	response to heat
ALVIN_RS05495	COG1131	(ABC) transporter
ALVIN_RS05500	COG0842	Transport permease protein
ALVIN_RS05505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ALVIN_RS05520	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ALVIN_RS05535	COG2046	Belongs to the sulfate adenylyltransferase family
ALVIN_RS05560	COG1047	Peptidyl-prolyl cis-trans
ALVIN_RS05575	COG0529	Catalyzes the synthesis of activated sulfate
ALVIN_RS05580	COG1199	ATP-dependent helicase activity
ALVIN_RS05600	COG0418	dihydroorotase activity
ALVIN_RS05605	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ALVIN_RS05610	COG1177	transmembrane transport
ALVIN_RS05615	COG1176	ABC-type spermidine putrescine transport system, permease component I
ALVIN_RS05620	COG3842	ATPase activity
ALVIN_RS05625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ALVIN_RS05630	COG0107	imidazoleglycerol-phosphate synthase activity
ALVIN_RS05640	COG0675	Transposase, IS605 OrfB family
ALVIN_RS05645	COG1272	protein, Hemolysin III
ALVIN_RS05680	COG5001	Diguanylate cyclase
ALVIN_RS05720	COG3459	Glycosyltransferase 36 associated
ALVIN_RS05730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ALVIN_RS05740	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ALVIN_RS05745	COG2205	protein histidine kinase activity
ALVIN_RS05750	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS05785	COG5001	Diguanylate cyclase
ALVIN_RS05790	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALVIN_RS05790	COG2878	Part of a membrane complex involved in electron transport
ALVIN_RS05795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ALVIN_RS05795	COG1013	pyruvate-flavodoxin oxidoreductase activity
ALVIN_RS05795	COG0674	pyruvate-flavodoxin oxidoreductase activity
ALVIN_RS05795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALVIN_RS05800	COG4656	Part of a membrane complex involved in electron transport
ALVIN_RS05805	COG4658	electron transport chain
ALVIN_RS05810	COG4659	FMN binding
ALVIN_RS05815	COG4660	Part of a membrane complex involved in electron transport
ALVIN_RS05820	COG4657	Part of a membrane complex involved in electron transport
ALVIN_RS05825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ALVIN_RS05830	COG0196	riboflavin kinase activity
ALVIN_RS05835	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
ALVIN_RS05845	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ALVIN_RS05895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ALVIN_RS05900	COG4181	ATPase activity
ALVIN_RS05915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALVIN_RS05920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ALVIN_RS05925	COG1862	Preprotein translocase
ALVIN_RS05930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALVIN_RS05930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ALVIN_RS05945	COG1528	Iron-storage protein
ALVIN_RS05985	COG0617	tRNA 3'-terminal CCA addition
ALVIN_RS05995	COG3437	response regulator, receiver
ALVIN_RS06005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALVIN_RS06010	COG0442	prolyl-tRNA aminoacylation
ALVIN_RS06020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ALVIN_RS06020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ALVIN_RS06025	COG0802	atpase or kinase
ALVIN_RS06030	COG0860	N-Acetylmuramoyl-L-alanine amidase
ALVIN_RS06035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ALVIN_RS06040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ALVIN_RS06045	COG1923	regulation of RNA biosynthetic process
ALVIN_RS06050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALVIN_RS06055	COG0330	HflC and HflK could
ALVIN_RS06060	COG0330	HflC and HflK could
ALVIN_RS06070	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ALVIN_RS06075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ALVIN_RS06090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ALVIN_RS06090	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALVIN_RS06120	COG0670	Belongs to the BI1 family
ALVIN_RS06125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ALVIN_RS06130	COG2954	triphosphatase activity
ALVIN_RS06140	COG1283	sodium-dependent phosphate transmembrane transporter activity
ALVIN_RS06155	COG0306	phosphate transporter
ALVIN_RS06160	COG1392	Phosphate transport regulator
ALVIN_RS06180	COG2221	Nitrite and sulphite reductase 4Fe-4S
ALVIN_RS06185	COG2221	Nitrite and sulphite reductase 4Fe-4S
ALVIN_RS06190	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ALVIN_RS06195	COG2923	Belongs to the DsrF TusC family
ALVIN_RS06205	COG2920	part of a sulfur-relay system
ALVIN_RS06240	COG1797	cobyrinic acid a,c-diamide synthase activity
ALVIN_RS06255	COG2255	four-way junction helicase activity
ALVIN_RS06290	COG1160	GTP binding
ALVIN_RS06305	COG0124	histidyl-tRNA synthetase
ALVIN_RS06320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ALVIN_RS06325	COG0105	UTP biosynthetic process
ALVIN_RS06340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ALVIN_RS06350	COG0557	exoribonuclease II activity
ALVIN_RS06355	COG3108	Peptidase M15
ALVIN_RS06405	COG0628	permease
ALVIN_RS06470	COG1902	pentaerythritol trinitrate reductase activity
ALVIN_RS06485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALVIN_RS06500	COG0243	molybdopterin cofactor binding
ALVIN_RS06550	COG0729	surface antigen
ALVIN_RS06555	COG2911	Protein conserved in bacteria
ALVIN_RS06560	COG1560	Kdo2-lipid A biosynthetic process
ALVIN_RS06575	COG1196	nuclear chromosome segregation
ALVIN_RS06580	COG3115	cell septum assembly
ALVIN_RS06585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ALVIN_RS06595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALVIN_RS06600	COG2350	Protein conserved in bacteria
ALVIN_RS06605	COG2917	probably involved in intracellular septation
ALVIN_RS06610	COG1115	amino acid carrier protein
ALVIN_RS06620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ALVIN_RS06630	COG4251	negative regulation of phosphorylation
ALVIN_RS06635	COG1394	ATPase activity, coupled to movement of substances
ALVIN_RS06645	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ALVIN_RS06660	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ALVIN_RS06665	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
ALVIN_RS06680	COG1269	ATP hydrolysis coupled proton transport
ALVIN_RS06700	COG0542	response to heat
ALVIN_RS06705	COG3409	Peptidoglycan-binding domain 1 protein
ALVIN_RS06705	COG3267	Type II secretory pathway component ExeA
ALVIN_RS06715	COG2239	Acts as a magnesium transporter
ALVIN_RS06755	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS06805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ALVIN_RS06820	COG0497	DNA recombination
ALVIN_RS06825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ALVIN_RS06830	COG1420	regulation of RNA biosynthetic process
ALVIN_RS06835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALVIN_RS06840	COG0443	Heat shock 70 kDa protein
ALVIN_RS06845	COG0484	heat shock protein binding
ALVIN_RS06855	COG0709	Synthesizes selenophosphate from selenide and ATP
ALVIN_RS06860	COG3276	selenocysteine insertion sequence binding
ALVIN_RS06870	COG2354	Protein conserved in bacteria
ALVIN_RS06875	COG3154	lipid carrier protein
ALVIN_RS06890	COG2862	Uncharacterized protein family, UPF0114
ALVIN_RS06895	COG4251	negative regulation of phosphorylation
ALVIN_RS06895	COG2203	Gaf domain
ALVIN_RS06895	COG5001	Diguanylate cyclase
ALVIN_RS06895	COG3706	GGDEF domain
ALVIN_RS06905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ALVIN_RS06925	COG3123	guanosine phosphorylase activity
ALVIN_RS06930	COG0651	ATP synthesis coupled electron transport
ALVIN_RS06935	COG0651	ATP synthesis coupled electron transport
ALVIN_RS06940	COG1007	ATP synthesis coupled electron transport
ALVIN_RS06945	COG0651	ATP synthesis coupled electron transport
ALVIN_RS06955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALVIN_RS06955	COG2111	Na H antiporter
ALVIN_RS06980	COG0318	PFAM AMP-dependent synthetase and ligase
ALVIN_RS06985	COG0033	Phosphoglucomutase
ALVIN_RS06990	COG0326	Molecular chaperone. Has ATPase activity
ALVIN_RS06995	COG0563	adenylate kinase activity
ALVIN_RS07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALVIN_RS07010	COG1959	2 iron, 2 sulfur cluster binding
ALVIN_RS07030	COG0740	serine-type endopeptidase activity
ALVIN_RS07035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ALVIN_RS07040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ALVIN_RS07060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ALVIN_RS07075	COG0601	transmembrane transport
ALVIN_RS07080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ALVIN_RS07095	COG0783	Belongs to the Dps family
ALVIN_RS07105	COG1674	ftsk spoiiie
ALVIN_RS07110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ALVIN_RS07115	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALVIN_RS07120	COG0463	Glycosyl transferase, family 2
ALVIN_RS07155	COG3093	addiction module antidote protein HigA
ALVIN_RS07170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ALVIN_RS07175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ALVIN_RS07205	COG1131	(ABC) transporter
ALVIN_RS07210	COG0842	Transport permease protein
ALVIN_RS07245	COG1064	alcohol dehydrogenase
ALVIN_RS07255	COG0590	tRNA wobble adenosine to inosine editing
ALVIN_RS07285	COG0443	Heat shock 70 kDa protein
ALVIN_RS07290	COG0297	glycogen (starch) synthase activity
ALVIN_RS07295	COG0366	Alpha amylase catalytic
ALVIN_RS07305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALVIN_RS07320	COG3122	Protein conserved in bacteria
ALVIN_RS07325	COG0084	hydrolase, TatD family'
ALVIN_RS07365	COG5002	protein histidine kinase activity
ALVIN_RS07365	COG2205	protein histidine kinase activity
ALVIN_RS07365	COG0784	Response regulator, receiver
ALVIN_RS07380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ALVIN_RS07385	COG2835	tetraacyldisaccharide 4'-kinase activity
ALVIN_RS07415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ALVIN_RS07420	COG0318	PFAM AMP-dependent synthetase and ligase
ALVIN_RS07430	COG0058	SHG alpha-glucan phosphorylase activity
ALVIN_RS07440	COG0045	succinate-CoA ligase (ADP-forming) activity
ALVIN_RS07445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ALVIN_RS07450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALVIN_RS07455	COG2920	part of a sulfur-relay system
ALVIN_RS07460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ALVIN_RS07465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ALVIN_RS07470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALVIN_RS07480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ALVIN_RS07485	COG2915	High frequency lysogenization protein hflD homolog
ALVIN_RS07490	COG0482	sulfurtransferase activity
ALVIN_RS07500	COG0726	polysaccharide deacetylase
ALVIN_RS07505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ALVIN_RS07505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ALVIN_RS07510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ALVIN_RS07515	COG2119	membrane
ALVIN_RS07525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS07530	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALVIN_RS07540	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ALVIN_RS07545	COG1918	ferrous iron import across plasma membrane
ALVIN_RS07570	COG0701	Predicted permease
ALVIN_RS07600	COG0463	Glycosyl transferase, family 2
ALVIN_RS07650	COG0322	excinuclease ABC activity
ALVIN_RS07655	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ALVIN_RS07660	COG0500	methyltransferase
ALVIN_RS07670	COG0616	signal peptide processing
ALVIN_RS07675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ALVIN_RS07680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ALVIN_RS07685	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ALVIN_RS07685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALVIN_RS07690	COG1511	domain protein
ALVIN_RS07690	COG3264	Mechanosensitive ion channel
ALVIN_RS07695	COG0589	response to stress
ALVIN_RS07730	COG0735	belongs to the Fur family
ALVIN_RS07735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ALVIN_RS07790	COG2201	protein-glutamate methylesterase activity
ALVIN_RS07795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALVIN_RS07800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALVIN_RS07805	COG0835	chemotaxis
ALVIN_RS07810	COG0840	transmembrane signaling receptor activity
ALVIN_RS07815	COG0643	Histidine kinase
ALVIN_RS07815	COG2198	Histidine kinase
ALVIN_RS07835	COG3290	protein histidine kinase activity
ALVIN_RS07835	COG0840	transmembrane signaling receptor activity
ALVIN_RS07845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ALVIN_RS07855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALVIN_RS07860	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ALVIN_RS07890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ALVIN_RS07895	COG0557	exoribonuclease II activity
ALVIN_RS07920	COG0285	dihydrofolate synthase activity
ALVIN_RS07925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ALVIN_RS07930	COG0159	tryptophan synthase activity
ALVIN_RS07935	COG0133	tryptophan synthase activity
ALVIN_RS07940	COG0135	phosphoribosylanthranilate isomerase activity
ALVIN_RS07945	COG0101	tRNA pseudouridine synthase activity
ALVIN_RS07960	COG0473	3-isopropylmalate dehydrogenase activity
ALVIN_RS07965	COG0066	3-isopropylmalate dehydratase activity
ALVIN_RS07970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ALVIN_RS08005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ALVIN_RS08015	COG1363	Peptidase, m42
ALVIN_RS08025	COG0367	asparagine synthase
ALVIN_RS08045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ALVIN_RS08065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ALVIN_RS08070	COG0424	maF-like protein
ALVIN_RS08085	COG1254	Belongs to the acylphosphatase family
ALVIN_RS08100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ALVIN_RS08105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ALVIN_RS08110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ALVIN_RS08135	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS08140	COG5002	protein histidine kinase activity
ALVIN_RS08145	COG0776	regulation of translation
ALVIN_RS08155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ALVIN_RS08160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ALVIN_RS08170	COG0717	Belongs to the dCTP deaminase family
ALVIN_RS08175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ALVIN_RS08185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ALVIN_RS08190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ALVIN_RS08215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ALVIN_RS08235	COG1286	toxin biosynthetic process
ALVIN_RS08245	COG1546	Belongs to the CinA family
ALVIN_RS08265	COG0511	ligase activity, forming carbon-carbon bonds
ALVIN_RS08265	COG5016	pyruvate
ALVIN_RS08270	COG0439	Biotin carboxylase
ALVIN_RS08285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ALVIN_RS08300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALVIN_RS08305	COG1120	ATPase activity
ALVIN_RS08345	COG3721	Heme iron utilization protein
ALVIN_RS08375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALVIN_RS08380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ALVIN_RS08395	COG4654	Cytochrome c, class I
ALVIN_RS08400	COG0582	viral genome integration into host DNA
ALVIN_RS08435	COG4983	Phage plasmid primase, P4 family domain protein
ALVIN_RS08490	COG1519	Transferase
ALVIN_RS08495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ALVIN_RS08500	COG1381	Involved in DNA repair and RecF pathway recombination
ALVIN_RS08510	COG0571	ribonuclease III activity
ALVIN_RS08520	COG0681	Belongs to the peptidase S26 family
ALVIN_RS08525	COG0481	GTPase activity
ALVIN_RS08530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ALVIN_RS08560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ALVIN_RS08560	COG1042	CoA-binding domain protein
ALVIN_RS08560	COG0045	succinate-CoA ligase (ADP-forming) activity
ALVIN_RS08565	COG0123	including yeast histone deacetylase and acetoin utilization protein
ALVIN_RS08575	COG2826	transposase and inactivated derivatives, IS30 family
ALVIN_RS08600	COG2154	pterin-4-alpha-carbinolamine dehydratase
ALVIN_RS08630	COG1342	Belongs to the UPF0251 family
ALVIN_RS08640	COG1160	GTP binding
ALVIN_RS08645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ALVIN_RS08665	COG0704	Plays a role in the regulation of phosphate uptake
ALVIN_RS08670	COG5002	protein histidine kinase activity
ALVIN_RS08680	COG0671	phosphoesterase, PA-phosphatase related
ALVIN_RS08690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ALVIN_RS08695	COG1509	lysine 2,3-aminomutase activity
ALVIN_RS08720	COG0489	protein tyrosine kinase activity
ALVIN_RS08770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ALVIN_RS08780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ALVIN_RS08785	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ALVIN_RS08805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALVIN_RS08805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ALVIN_RS08810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALVIN_RS08815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ALVIN_RS08825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ALVIN_RS08830	COG0583	DNA-binding transcription factor activity
ALVIN_RS08835	COG0367	asparagine synthase
ALVIN_RS08840	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS08870	COG0489	protein tyrosine kinase activity
ALVIN_RS08885	COG2204	response regulator
ALVIN_RS08890	COG2205	protein histidine kinase activity
ALVIN_RS08890	COG0784	Response regulator, receiver
ALVIN_RS08905	COG2226	methyltransferase
ALVIN_RS08915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ALVIN_RS08920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALVIN_RS08935	COG0463	Glycosyl transferase, family 2
ALVIN_RS08945	COG2244	polysaccharide biosynthetic process
ALVIN_RS08980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ALVIN_RS08995	COG0367	asparagine synthase
ALVIN_RS09015	COG2217	Heavy metal translocating P-type atpase
ALVIN_RS09020	COG1797	cobyrinic acid a,c-diamide synthase activity
ALVIN_RS09030	COG1253	flavin adenine dinucleotide binding
ALVIN_RS09060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ALVIN_RS09065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ALVIN_RS09105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ALVIN_RS09130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ALVIN_RS09135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ALVIN_RS09150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ALVIN_RS09160	COG5265	(ABC) transporter
ALVIN_RS09165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ALVIN_RS09170	COG2010	Cytochrome c
ALVIN_RS09175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ALVIN_RS09175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALVIN_RS09180	COG2224	Isocitrate lyase
ALVIN_RS09185	COG0259	pyridoxamine-phosphate oxidase activity
ALVIN_RS09200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ALVIN_RS09205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALVIN_RS09215	COG1022	Amp-dependent synthetase and ligase
ALVIN_RS09225	COG1194	a g-specific adenine glycosylase
ALVIN_RS09230	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ALVIN_RS09240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ALVIN_RS09270	COG1183	phosphatidylcholine synthase activity
ALVIN_RS09275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ALVIN_RS09285	COG3383	formate dehydrogenase (NAD+) activity
ALVIN_RS09290	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
ALVIN_RS09295	COG3259	Nickel-dependent hydrogenase
ALVIN_RS09310	COG0840	transmembrane signaling receptor activity
ALVIN_RS09315	COG2205	protein histidine kinase activity
ALVIN_RS09315	COG0784	Response regulator, receiver
ALVIN_RS09335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALVIN_RS09355	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ALVIN_RS09380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ALVIN_RS09385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ALVIN_RS09390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALVIN_RS09395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ALVIN_RS09400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ALVIN_RS09415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ALVIN_RS09420	COG0416	fatty acid biosynthetic process
ALVIN_RS09425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ALVIN_RS09435	COG4566	intracellular signal transduction
ALVIN_RS09455	COG2304	oxidoreductase activity
ALVIN_RS09470	COG0714	Associated with various cellular activities
ALVIN_RS09480	COG0439	Biotin carboxylase
ALVIN_RS09485	COG0511	ligase activity, forming carbon-carbon bonds
ALVIN_RS09490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ALVIN_RS09495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALVIN_RS09500	COG4232	protein-disulfide reductase activity
ALVIN_RS09505	COG1324	tolerance protein
ALVIN_RS09510	COG3030	protein affecting phage T7 exclusion by the F plasmid
ALVIN_RS09535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ALVIN_RS09545	COG0367	asparagine synthase
ALVIN_RS09550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ALVIN_RS09555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ALVIN_RS09570	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ALVIN_RS09575	COG0129	dihydroxy-acid dehydratase activity
ALVIN_RS09580	COG0521	Mo-molybdopterin cofactor biosynthetic process
ALVIN_RS09585	COG0303	'Molybdopterin
ALVIN_RS09590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ALVIN_RS09605	COG0277	FAD linked oxidase domain protein
ALVIN_RS09640	COG0535	radical SAM domain protein
ALVIN_RS09665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALVIN_RS09695	COG4106	trans-aconitate 2-methyltransferase activity
ALVIN_RS09725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALVIN_RS09730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ALVIN_RS09750	COG1053	succinate dehydrogenase
ALVIN_RS09775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ALVIN_RS09780	COG1216	Glycosyl transferase, family 2
ALVIN_RS09795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALVIN_RS09800	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ALVIN_RS09805	COG0697	spore germination
ALVIN_RS09820	COG3437	response regulator, receiver
ALVIN_RS09825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ALVIN_RS09830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ALVIN_RS09835	COG0189	ligase activity
ALVIN_RS09845	COG0471	metal ion transport
ALVIN_RS09845	COG3273	potassium ion transport
ALVIN_RS09850	COG1643	Atp-dependent helicase
ALVIN_RS09870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ALVIN_RS09880	COG3300	MHYT domain
ALVIN_RS09880	COG5001	Diguanylate cyclase
ALVIN_RS09890	COG0402	S-adenosylhomocysteine deaminase activity
ALVIN_RS09905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ALVIN_RS09920	COG0359	binds to the 23S rRNA
ALVIN_RS09935	COG0360	Binds together with S18 to 16S ribosomal RNA
ALVIN_RS09955	COG2716	regulation of RNA biosynthetic process
ALVIN_RS09960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ALVIN_RS09970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ALVIN_RS10005	COG0489	protein tyrosine kinase activity
ALVIN_RS10010	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ALVIN_RS10015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ALVIN_RS10030	COG1643	Atp-dependent helicase
ALVIN_RS10035	COG3338	carbonate dehydratase activity
ALVIN_RS10060	COG1408	metallophosphoesterase
ALVIN_RS10080	COG4245	von Willebrand factor, type A
ALVIN_RS10105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ALVIN_RS10120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ALVIN_RS10140	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ALVIN_RS10170	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ALVIN_RS10175	COG0024	Methionine aminopeptidase
ALVIN_RS10180	COG0052	Belongs to the universal ribosomal protein uS2 family
ALVIN_RS10185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ALVIN_RS10190	COG0528	UMP kinase activity
ALVIN_RS10195	COG0233	cytoplasmic translational termination
ALVIN_RS10200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ALVIN_RS10220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALVIN_RS10230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALVIN_RS10235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ALVIN_RS10240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ALVIN_RS10250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ALVIN_RS10260	COG0019	diaminopimelate decarboxylase activity
ALVIN_RS10275	COG0708	Exodeoxyribonuclease III
ALVIN_RS10285	COG1331	Highly conserved protein containing a thioredoxin domain
ALVIN_RS10305	COG0009	L-threonylcarbamoyladenylate synthase
ALVIN_RS10320	COG2922	Belongs to the Smg family
ALVIN_RS10325	COG0758	DNA mediated transformation
ALVIN_RS10335	COG0242	peptide deformylase activity
ALVIN_RS10340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ALVIN_RS10360	COG2204	response regulator
ALVIN_RS10365	COG0569	domain protein
ALVIN_RS10370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ALVIN_RS10375	COG1763	Mo-molybdopterin cofactor biosynthetic process
ALVIN_RS10380	COG0287	Prephenate dehydrogenase
ALVIN_RS10385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALVIN_RS10390	COG0077	Prephenate dehydratase
ALVIN_RS10390	COG1605	Chorismate mutase
ALVIN_RS10395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ALVIN_RS10415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ALVIN_RS10425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ALVIN_RS10440	COG2770	Histidine kinase
ALVIN_RS10440	COG2208	phosphoserine phosphatase activity
ALVIN_RS10455	COG1366	Belongs to the anti-sigma-factor antagonist family
ALVIN_RS10460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ALVIN_RS10485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ALVIN_RS10490	COG0676	glucose-6-phosphate 1-epimerase activity
ALVIN_RS10495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALVIN_RS10495	COG0574	Belongs to the PEP-utilizing enzyme family
ALVIN_RS10500	COG0525	valine-tRNA ligase activity
ALVIN_RS10520	COG4783	chaperone-mediated protein folding
ALVIN_RS10535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ALVIN_RS10540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ALVIN_RS10545	COG1162	GTPase activity
ALVIN_RS10560	COG1278	Cold shock
ALVIN_RS10565	COG2183	response to ionizing radiation
ALVIN_RS10580	COG1968	undecaprenyl-diphosphatase activity
ALVIN_RS10590	COG0436	Aminotransferase
ALVIN_RS10600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ALVIN_RS10610	COG0297	glycogen (starch) synthase activity
ALVIN_RS10630	COG2814	Major facilitator Superfamily
ALVIN_RS10635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ALVIN_RS10640	COG1538	Outer membrane efflux protein
ALVIN_RS10665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ALVIN_RS10685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ALVIN_RS10690	COG0446	pyridine nucleotide-disulphide oxidoreductase
ALVIN_RS10695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ALVIN_RS10710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ALVIN_RS10715	COG2967	ApaG domain
ALVIN_RS10725	COG0429	hydrolase of the alpha beta-hydrolase fold
ALVIN_RS10735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALVIN_RS10745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ALVIN_RS10750	COG0142	geranyltranstransferase activity
ALVIN_RS10775	COG3162	membrane
ALVIN_RS10780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALVIN_RS10785	COG4251	negative regulation of phosphorylation
ALVIN_RS10785	COG3706	GGDEF domain
ALVIN_RS10785	COG2203	Gaf domain
ALVIN_RS10785	COG5001	Diguanylate cyclase
ALVIN_RS10790	COG2205	protein histidine kinase activity
ALVIN_RS10790	COG0784	Response regulator, receiver
ALVIN_RS10790	COG5002	protein histidine kinase activity
ALVIN_RS10795	COG0737	Belongs to the 5'-nucleotidase family
ALVIN_RS10830	COG0116	Belongs to the methyltransferase superfamily
ALVIN_RS10830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ALVIN_RS10835	COG4133	protoheme IX ABC transporter activity
ALVIN_RS10845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALVIN_RS10855	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ALVIN_RS10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ALVIN_RS10870	COG4235	cytochrome complex assembly
ALVIN_RS10870	COG3088	subunit of a heme lyase
ALVIN_RS10880	COG1881	PFAM PEBP family protein
ALVIN_RS10885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALVIN_RS10895	COG3409	Peptidoglycan-binding domain 1 protein
ALVIN_RS10895	COG3773	Cell wall hydrolase
ALVIN_RS10900	COG0586	Pfam SNARE associated Golgi protein
ALVIN_RS10905	COG0733	neurotransmitter:sodium symporter activity
ALVIN_RS10910	COG1686	Belongs to the peptidase S11 family
ALVIN_RS10915	COG1187	pseudouridine synthase activity
ALVIN_RS10920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ALVIN_RS10930	COG0180	Tryptophanyl-tRNA synthetase
ALVIN_RS10935	COG1994	Peptidase M50
ALVIN_RS10940	COG0009	L-threonylcarbamoyladenylate synthase
ALVIN_RS10945	COG0613	PHP domain protein
ALVIN_RS10985	COG3045	CreA protein
ALVIN_RS10990	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALVIN_RS11005	COG2718	Belongs to the UPF0229 family
ALVIN_RS11010	COG2766	serine protein kinase
ALVIN_RS11020	COG0840	transmembrane signaling receptor activity
ALVIN_RS11025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ALVIN_RS11030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ALVIN_RS11040	COG2974	May be involved in recombination
ALVIN_RS11045	COG4536	flavin adenine dinucleotide binding
ALVIN_RS11050	COG2211	Major facilitator Superfamily
ALVIN_RS11060	COG1278	Cold shock
ALVIN_RS11065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ALVIN_RS11070	COG0542	response to heat
ALVIN_RS11075	COG0840	transmembrane signaling receptor activity
ALVIN_RS11080	COG1492	cobalamin metabolic process
ALVIN_RS11090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALVIN_RS11095	COG0084	hydrolase, TatD family'
ALVIN_RS11110	COG0840	transmembrane signaling receptor activity
ALVIN_RS11135	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ALVIN_RS11150	COG2198	Histidine kinase
ALVIN_RS11150	COG0643	Histidine kinase
ALVIN_RS11155	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS11160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ALVIN_RS11175	COG0735	belongs to the Fur family
ALVIN_RS11200	COG4771	TonB-dependent receptor
ALVIN_RS11205	COG0811	peptide transport
ALVIN_RS11210	COG0848	biopolymer transport protein
ALVIN_RS11235	COG1918	ferrous iron import across plasma membrane
ALVIN_RS11235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ALVIN_RS11240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ALVIN_RS11240	COG1918	ferrous iron import across plasma membrane
ALVIN_RS11245	COG3706	GGDEF domain
ALVIN_RS11260	COG0583	DNA-binding transcription factor activity
ALVIN_RS11265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ALVIN_RS11270	COG0735	belongs to the Fur family
ALVIN_RS11290	COG3443	Belongs to the bacterial solute-binding protein 9 family
ALVIN_RS11290	COG0803	Belongs to the bacterial solute-binding protein 9 family
ALVIN_RS11300	COG2867	negative regulation of translational initiation
ALVIN_RS11305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ALVIN_RS11315	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ALVIN_RS11330	COG0791	NLP P60 protein
ALVIN_RS11335	COG0492	ferredoxin-NADP+ reductase activity
ALVIN_RS11340	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ALVIN_RS11345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ALVIN_RS11355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ALVIN_RS11360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ALVIN_RS11370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ALVIN_RS11375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ALVIN_RS11380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ALVIN_RS11400	COG0284	orotidine-5'-phosphate decarboxylase activity
ALVIN_RS11405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ALVIN_RS11425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ALVIN_RS11425	COG1328	CTP reductase activity
ALVIN_RS11505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ALVIN_RS11515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ALVIN_RS11535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ALVIN_RS11540	COG0784	Response regulator, receiver
ALVIN_RS11540	COG2205	protein histidine kinase activity
ALVIN_RS11540	COG5002	protein histidine kinase activity
ALVIN_RS11585	COG2960	long-chain fatty acid transporting porin activity
ALVIN_RS11600	COG0004	ammonium transporteR
ALVIN_RS11620	COG0137	argininosuccinate synthase activity
ALVIN_RS11640	COG0513	Belongs to the DEAD box helicase family
ALVIN_RS11650	COG0203	ribosomal protein L17
ALVIN_RS11655	COG0202	RNA polymerase activity
ALVIN_RS11660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ALVIN_RS11665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ALVIN_RS11670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALVIN_RS11675	COG0201	protein transport
ALVIN_RS11680	COG0200	Binds to the 23S rRNA
ALVIN_RS11685	COG1841	ribosomal large subunit assembly
ALVIN_RS11690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ALVIN_RS11695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ALVIN_RS11700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ALVIN_RS11705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ALVIN_RS11710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ALVIN_RS11715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALVIN_RS11720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ALVIN_RS11725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ALVIN_RS11730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ALVIN_RS11735	COG0255	Belongs to the universal ribosomal protein uL29 family
ALVIN_RS11740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ALVIN_RS11745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ALVIN_RS11750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ALVIN_RS11755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ALVIN_RS11760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALVIN_RS11765	COG0089	rRNA binding
ALVIN_RS11770	COG0088	Forms part of the polypeptide exit tunnel
ALVIN_RS11775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ALVIN_RS11780	COG0051	transcription antitermination factor activity, RNA binding
ALVIN_RS11785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALVIN_RS11790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALVIN_RS11795	COG0049	tRNA binding
ALVIN_RS11800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ALVIN_RS11805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ALVIN_RS11810	COG0085	RNA polymerase activity
ALVIN_RS11815	COG0222	ribosome binding
ALVIN_RS11820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ALVIN_RS11825	COG0081	regulation of translation
ALVIN_RS11830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ALVIN_RS11850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ALVIN_RS11880	COG0193	aminoacyl-tRNA hydrolase activity
ALVIN_RS11885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ALVIN_RS11890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ALVIN_RS11900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ALVIN_RS11910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ALVIN_RS11915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ALVIN_RS11945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ALVIN_RS11960	COG2205	protein histidine kinase activity
ALVIN_RS11960	COG0784	Response regulator, receiver
ALVIN_RS11960	COG5002	protein histidine kinase activity
ALVIN_RS11965	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ALVIN_RS11970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALVIN_RS11975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ALVIN_RS12035	COG0582	viral genome integration into host DNA
ALVIN_RS12045	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ALVIN_RS12050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ALVIN_RS12055	COG1007	ATP synthesis coupled electron transport
ALVIN_RS12080	COG0713	ATP synthesis coupled electron transport
ALVIN_RS12090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS12095	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ALVIN_RS12110	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ALVIN_RS12115	COG0649	NAD binding
ALVIN_RS12120	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS12125	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS12130	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ALVIN_RS12145	COG0149	triose-phosphate isomerase activity
ALVIN_RS12150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ALVIN_RS12175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ALVIN_RS12180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ALVIN_RS12185	COG0583	DNA-binding transcription factor activity
ALVIN_RS12190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ALVIN_RS12195	COG4208	sulfate ABC transporter
ALVIN_RS12200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ALVIN_RS12205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ALVIN_RS12210	COG0583	DNA-binding transcription factor activity
ALVIN_RS12215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ALVIN_RS12220	COG0175	sulfate reduction
ALVIN_RS12230	COG2895	sulfate adenylyltransferase (ATP) activity
ALVIN_RS12235	COG0709	Synthesizes selenophosphate from selenide and ATP
ALVIN_RS12240	COG0243	molybdopterin cofactor binding
ALVIN_RS12240	COG3383	formate dehydrogenase (NAD+) activity
ALVIN_RS12245	COG0243	molybdopterin cofactor binding
ALVIN_RS12245	COG3383	formate dehydrogenase (NAD+) activity
ALVIN_RS12250	COG0437	4 iron, 4 sulfur cluster binding
ALVIN_RS12255	COG2864	formate dehydrogenase
ALVIN_RS12270	COG0617	tRNA 3'-terminal CCA addition
ALVIN_RS12270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ALVIN_RS12270	COG3620	sequence-specific DNA binding
ALVIN_RS12285	COG1720	tRNA m6t6A37 methyltransferase activity
ALVIN_RS12290	COG2201	protein-glutamate methylesterase activity
ALVIN_RS12295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ALVIN_RS12295	COG1776	CheC inhibitor of MCP methylation
ALVIN_RS12300	COG2203	Gaf domain
ALVIN_RS12300	COG4251	negative regulation of phosphorylation
ALVIN_RS12300	COG5001	Diguanylate cyclase
ALVIN_RS12300	COG3706	GGDEF domain
ALVIN_RS12305	COG0840	transmembrane signaling receptor activity
ALVIN_RS12315	COG2201	protein-glutamate methylesterase activity
ALVIN_RS12325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALVIN_RS12335	COG2198	Histidine kinase
ALVIN_RS12335	COG0643	Histidine kinase
ALVIN_RS12345	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS12350	COG0840	transmembrane signaling receptor activity
ALVIN_RS12355	COG1366	Belongs to the anti-sigma-factor antagonist family
ALVIN_RS12360	COG1366	Belongs to the anti-sigma-factor antagonist family
ALVIN_RS12365	COG2172	sigma factor antagonist activity
ALVIN_RS12370	COG2172	sigma factor antagonist activity
ALVIN_RS12385	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS12390	COG2925	Exonuclease
ALVIN_RS12395	COG0335	large ribosomal subunit rRNA binding
ALVIN_RS12400	COG0336	Belongs to the RNA methyltransferase TrmD family
ALVIN_RS12405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ALVIN_RS12410	COG0228	four-way junction DNA binding
ALVIN_RS12415	COG0750	zinc metalloprotease
ALVIN_RS12430	COG3302	dmso reductase anchor subunit
ALVIN_RS12435	COG0437	4 iron, 4 sulfur cluster binding
ALVIN_RS12440	COG0243	molybdopterin cofactor binding
ALVIN_RS12450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ALVIN_RS12460	COG0488	(ABC) transporter
ALVIN_RS12480	COG1271	oxidase subunit
ALVIN_RS12485	COG1294	oxidase, subunit
ALVIN_RS12495	COG3047	cAMP biosynthetic process
ALVIN_RS12495	COG2885	chlorophyll binding
ALVIN_RS12510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ALVIN_RS12525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ALVIN_RS12560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALVIN_RS12570	COG3830	Belongs to the UPF0237 family
ALVIN_RS12570	COG0560	Phosphoserine phosphatase
ALVIN_RS12575	COG0312	modulator of DNA gyrase
ALVIN_RS12580	COG0312	modulator of DNA gyrase
ALVIN_RS12585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ALVIN_RS12600	COG0424	maF-like protein
ALVIN_RS12605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ALVIN_RS12610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ALVIN_RS12640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ALVIN_RS12645	COG4636	protein conserved in cyanobacteria
ALVIN_RS12650	COG2951	lytic endotransglycosylase activity
ALVIN_RS12660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ALVIN_RS12670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ALVIN_RS12685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ALVIN_RS12690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ALVIN_RS12695	COG1850	ribulose-bisphosphate carboxylase activity
ALVIN_RS12700	COG0432	Pfam Uncharacterised protein family UPF0047
ALVIN_RS12745	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ALVIN_RS12765	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ALVIN_RS12770	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ALVIN_RS12775	COG1063	alcohol dehydrogenase
ALVIN_RS12780	COG0500	methyltransferase
ALVIN_RS12785	COG0142	geranyltranstransferase activity
ALVIN_RS12805	COG1562	ergosterol biosynthetic process
ALVIN_RS12810	COG1233	COG1233 Phytoene dehydrogenase and related
ALVIN_RS12850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ALVIN_RS12885	COG2205	protein histidine kinase activity
ALVIN_RS12890	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS12900	COG1358	cellular component organization or biogenesis
ALVIN_RS12935	COG2310	stress, protein
ALVIN_RS12965	COG0675	Transposase, IS605 OrfB family
ALVIN_RS12970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ALVIN_RS12970	COG1648	precorrin-2 dehydrogenase activity
ALVIN_RS12975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ALVIN_RS12980	COG0425	Belongs to the sulfur carrier protein TusA family
ALVIN_RS12985	COG2210	Belongs to the sulfur carrier protein TusA family
ALVIN_RS12990	COG0028	Belongs to the TPP enzyme family
ALVIN_RS12995	COG4251	negative regulation of phosphorylation
ALVIN_RS13000	COG0784	Response regulator, receiver
ALVIN_RS13005	COG2205	protein histidine kinase activity
ALVIN_RS13005	COG0784	Response regulator, receiver
ALVIN_RS13010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ALVIN_RS13025	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS13030	COG0438	transferase activity, transferring glycosyl groups
ALVIN_RS13035	COG0408	coproporphyrinogen oxidase activity
ALVIN_RS13045	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS13050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ALVIN_RS13055	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ALVIN_RS13075	COG0745	RESPONSE REGULATOR receiver
ALVIN_RS13105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ALVIN_RS13115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ALVIN_RS13140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALVIN_RS13170	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ALVIN_RS13175	COG1429	ligase activity, forming nitrogen-metal bonds
ALVIN_RS13180	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ALVIN_RS13185	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ALVIN_RS13205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ALVIN_RS13210	COG0644	oxidoreductase
ALVIN_RS13230	COG1136	(ABC) transporter
ALVIN_RS13230	COG0577	efflux transmembrane transporter activity
ALVIN_RS13255	COG0793	Belongs to the peptidase S41A family
ALVIN_RS13275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALVIN_RS13285	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ALVIN_RS13290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ALVIN_RS13310	COG0505	Belongs to the CarA family
ALVIN_RS13315	COG2205	protein histidine kinase activity
ALVIN_RS13315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALVIN_RS13325	COG2166	iron-sulfur cluster assembly
ALVIN_RS13350	COG4657	Part of a membrane complex involved in electron transport
ALVIN_RS13355	COG2878	Part of a membrane complex involved in electron transport
ALVIN_RS13360	COG4656	Part of a membrane complex involved in electron transport
ALVIN_RS13365	COG4658	electron transport chain
ALVIN_RS13380	COG2914	Belongs to the UPF0125 (RnfH) family
ALVIN_RS13385	COG0704	Plays a role in the regulation of phosphate uptake
ALVIN_RS13395	COG4535	Mg2 and Co2 transporter CorC
ALVIN_RS13400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ALVIN_RS13405	COG1702	phosphate starvation-inducible protein PhoH
ALVIN_RS13410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ALVIN_RS13420	COG1584	GPR1 FUN34 yaaH family protein
ALVIN_RS13425	COG1217	gtp-binding protein TYPA
ALVIN_RS13430	COG0714	Associated with various cellular activities
ALVIN_RS13485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ALVIN_RS13505	COG2703	oxygen carrier activity
ALVIN_RS13515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ALVIN_RS13515	COG0519	Catalyzes the synthesis of GMP from XMP
ALVIN_RS13520	COG0517	IMP dehydrogenase activity
ALVIN_RS13520	COG0516	GMP reductase activity
ALVIN_RS13525	COG1570	exodeoxyribonuclease VII activity
ALVIN_RS13535	COG0488	(ABC) transporter
ALVIN_RS13550	COG0058	SHG alpha-glucan phosphorylase activity
ALVIN_RS13555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ALVIN_RS13585	COG0693	protein deglycase activity
ALVIN_RS13590	COG0167	dihydroorotate dehydrogenase activity
ALVIN_RS13605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ALVIN_RS13610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ALVIN_RS13620	COG2022	thiamine diphosphate biosynthetic process
ALVIN_RS13625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ALVIN_RS13630	COG1122	ATPase activity
ALVIN_RS13635	COG0390	transport system, permease component
ALVIN_RS13640	COG0579	oxidoreductase
ALVIN_RS13645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ALVIN_RS13680	COG0166	Belongs to the GPI family
ALVIN_RS13685	COG0583	DNA-binding transcription factor activity
ALVIN_RS13700	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ALVIN_RS13705	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ALVIN_RS13730	COG4451	ribulose bisphosphate carboxylase, small
ALVIN_RS13735	COG1850	ribulose-bisphosphate carboxylase activity
ALVIN_RS13745	COG0659	secondary active sulfate transmembrane transporter activity
ALVIN_RS13750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ALVIN_RS13755	COG0297	glycogen (starch) synthase activity
ALVIN_RS13760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ALVIN_RS13765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ALVIN_RS13770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ALVIN_RS13775	COG0617	tRNA 3'-terminal CCA addition
ALVIN_RS13790	COG0602	queuosine metabolic process
ALVIN_RS13795	COG0720	synthase
ALVIN_RS13800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ALVIN_RS13810	COG3909	cytochrome
ALVIN_RS13815	COG0375	protein maturation
ALVIN_RS13820	COG0513	Belongs to the DEAD box helicase family
ALVIN_RS13825	COG0724	RNA recognition motif
ALVIN_RS13830	COG1151	hydroxylamine reductase activity
ALVIN_RS13840	COG3956	TIGRFAM MazG family protein
ALVIN_RS13855	COG0714	Associated with various cellular activities
ALVIN_RS13860	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ALVIN_RS13865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ALVIN_RS13885	COG2814	Major facilitator Superfamily
ALVIN_RS13900	COG0464	growth
ALVIN_RS13905	COG1404	Belongs to the peptidase S8 family
ALVIN_RS13915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALVIN_RS13920	COG0131	Imidazoleglycerol-phosphate dehydratase
ALVIN_RS13925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ALVIN_RS13930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ALVIN_RS13935	COG0140	phosphoribosyl-ATP diphosphatase activity
ALVIN_RS13945	COG0583	DNA-binding transcription factor activity
ALVIN_RS13965	COG0298	carbon dioxide binding
ALVIN_RS13970	COG2813	Specifically methylates the guanine in position
ALVIN_RS13975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALVIN_RS13995	COG0840	transmembrane signaling receptor activity
ALVIN_RS13995	COG3290	protein histidine kinase activity
ALVIN_RS14045	COG1752	Esterase of the alpha-beta hydrolase superfamily
ALVIN_RS14055	COG0189	ligase activity
ALVIN_RS14060	COG1032	radical SAM domain protein
ALVIN_RS14065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ALVIN_RS14080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ALVIN_RS14110	COG0189	ligase activity
ALVIN_RS14110	COG0569	domain protein
ALVIN_RS14125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ALVIN_RS14135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ALVIN_RS14140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ALVIN_RS14155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ALVIN_RS14160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ALVIN_RS14165	COG1127	ABC transporter
ALVIN_RS14175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ALVIN_RS14190	COG1137	ATPase activity
ALVIN_RS14215	COG1660	Displays ATPase and GTPase activities
ALVIN_RS14225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ALVIN_RS14230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ALVIN_RS14235	COG2239	Acts as a magnesium transporter
ALVIN_RS14240	COG0154	amidase activity
ALVIN_RS14245	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ALVIN_RS14250	COG1077	Cell shape determining protein MreB Mrl
ALVIN_RS14255	COG1792	Involved in formation and maintenance of cell shape
ALVIN_RS14260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ALVIN_RS14265	COG0768	penicillin binding
ALVIN_RS14270	COG0772	Belongs to the SEDS family
ALVIN_RS14275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ALVIN_RS14280	COG1686	Belongs to the peptidase S11 family
ALVIN_RS14285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ALVIN_RS14295	COG0321	lipoyl(octanoyl) transferase activity
ALVIN_RS14325	COG4636	protein conserved in cyanobacteria
ALVIN_RS14345	COG1999	signal sequence binding
ALVIN_RS14350	COG2847	Copper chaperone PCu(A)C
ALVIN_RS14380	COG1215	transferase activity, transferring glycosyl groups
ALVIN_RS14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ALVIN_RS14390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ALVIN_RS14395	COG0742	ribosomal rna small subunit methyltransferase
ALVIN_RS14400	COG0612	Peptidase, M16
ALVIN_RS14405	COG0612	Peptidase, M16
ALVIN_RS14410	COG0552	protein localization to endoplasmic reticulum
ALVIN_RS14415	COG2884	Cell division ATP-binding protein ftsE
ALVIN_RS14420	COG2177	Part of the ABC transporter FtsEX involved in
ALVIN_RS14430	COG1872	DUF167
ALVIN_RS14450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ALVIN_RS14455	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ALVIN_RS14465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ALVIN_RS14470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ALVIN_RS14490	COG0006	proline dipeptidase activity
ALVIN_RS14495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALVIN_RS14500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ALVIN_RS14505	COG0205	6-phosphofructokinase activity
ALVIN_RS14510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ALVIN_RS14515	COG0315	cyclic pyranopterin monophosphate synthase activity
ALVIN_RS14520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ALVIN_RS14540	COG0835	chemotaxis
ALVIN_RS14545	COG1360	Flagellar Motor Protein
ALVIN_RS14550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ALVIN_RS14555	COG2201	protein-glutamate methylesterase activity
ALVIN_RS14560	COG2198	Histidine kinase
ALVIN_RS14560	COG0784	Response regulator, receiver
ALVIN_RS14560	COG0643	Histidine kinase
ALVIN_RS14565	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ALVIN_RS14595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ALVIN_RS14680	COG1677	Flagellar hook-basal body complex protein FliE
ALVIN_RS14785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALVIN_RS14795	COG3706	GGDEF domain
ALVIN_RS14800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ALVIN_RS14805	COG1376	ErfK ybiS ycfS ynhG family protein
ALVIN_RS14830	COG0516	GMP reductase activity
ALVIN_RS14830	COG0517	IMP dehydrogenase activity
ALVIN_RS14835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ALVIN_RS14845	COG2226	methyltransferase
ALVIN_RS14855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ALVIN_RS14860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ALVIN_RS14870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ALVIN_RS14875	COG1758	RNA polymerase activity
ALVIN_RS14880	COG0194	GDP metabolic process
ALVIN_RS14885	COG1561	YicC-like family, N-terminal region
ALVIN_RS14890	COG0515	serine threonine protein kinase
ALVIN_RS14890	COG3266	domain, Protein
ALVIN_RS14895	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ALVIN_RS14905	COG0583	DNA-binding transcription factor activity
ALVIN_RS14910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ALVIN_RS14920	COG2003	Belongs to the UPF0758 family
ALVIN_RS14925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ALVIN_RS14930	COG0756	dUTP diphosphatase activity
ALVIN_RS14935	COG0840	transmembrane signaling receptor activity
ALVIN_RS14940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ALVIN_RS14950	COG2204	response regulator
ALVIN_RS14955	COG3852	Histidine kinase
ALVIN_RS14965	COG0174	glutamine synthetase
ALVIN_RS14970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ALVIN_RS14975	COG0752	glycyl-tRNA synthetase alpha subunit
ALVIN_RS14980	COG0751	glycine-tRNA ligase activity
ALVIN_RS14995	COG1450	Type ii and iii secretion system protein
ALVIN_RS15015	COG3156	type II secretion system protein K
ALVIN_RS15025	COG2165	general secretion pathway protein
ALVIN_RS15030	COG4970	Tfp pilus assembly protein FimT
ALVIN_RS15040	COG1459	type II secretion system
ALVIN_RS15075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALVIN_RS15080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ALVIN_RS15090	COG0793	Belongs to the peptidase S41A family
ALVIN_RS15095	COG4942	peptidase
ALVIN_RS15105	COG1054	Belongs to the UPF0176 family
ALVIN_RS15110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ALVIN_RS15115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ALVIN_RS15120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ALVIN_RS15135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ALVIN_RS15145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ALVIN_RS15170	COG0633	Ferredoxin
ALVIN_RS15195	COG0513	Belongs to the DEAD box helicase family
ALVIN_RS15200	COG0210	DNA helicase
ALVIN_RS15205	COG0539	negative regulation of cytoplasmic translation
ALVIN_RS15210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ALVIN_RS15215	COG0254	rRNA binding
ALVIN_RS15220	COG0281	malic enzyme
ALVIN_RS15225	COG0372	Belongs to the citrate synthase family
ALVIN_RS15260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ALVIN_RS15265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ALVIN_RS15285	COG2084	Dehydrogenase
ALVIN_RS15290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ALVIN_RS15320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ALVIN_RS15345	COG0445	tRNA wobble uridine modification
ALVIN_RS15350	COG0714	Associated with various cellular activities
ALVIN_RS15355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ALVIN_RS15390	COG2205	protein histidine kinase activity
ALVIN_RS15395	COG0037	tRNA processing
ALVIN_RS15410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ALVIN_RS15415	COG3038	cytochrome b561
ALVIN_RS15420	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ALVIN_RS15440	COG1074	ATP-dependent DNA helicase activity
ALVIN_RS15445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ALVIN_RS15455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ALVIN_RS15455	COG2111	Na H antiporter
ALVIN_RS15460	COG1006	Multisubunit Na H antiporter MnhC subunit
ALVIN_RS15465	COG0651	ATP synthesis coupled electron transport
ALVIN_RS15470	COG1863	multisubunit Na H antiporter MnhE subunit
ALVIN_RS15475	COG2212	antiporter activity
ALVIN_RS15480	COG1320	monovalent cation:proton antiporter activity
ALVIN_RS15485	COG0314	molybdopterin synthase activity
ALVIN_RS15490	COG0004	ammonium transporteR
ALVIN_RS15505	COG3001	Fructosamine kinase
ALVIN_RS15515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ALVIN_RS15520	COG0018	arginyl-trna synthetase
ALVIN_RS15530	COG0531	amino acid
ALVIN_RS15550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ALVIN_RS15560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ALVIN_RS15565	COG0706	membrane insertase activity
ALVIN_RS15810	COG0070	glutamate synthase
ALVIN_RS15810	COG0069	glutamate synthase activity
ALVIN_RS15810	COG0067	glutamate synthase
ALVIN_RS16000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ALVIN_RS16175	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ALVIN_RS16395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ALVIN_RS16400	COG1216	Glycosyl transferase, family 2
ALVIN_RS16430	COG5001	Diguanylate cyclase
ALVIN_RS16430	COG3300	MHYT domain
ALVIN_RS16455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ALVIN_RS16460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ALVIN_RS16465	COG0513	Belongs to the DEAD box helicase family
ALVIN_RS16495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ALVIN_RS16495	COG2205	protein histidine kinase activity
ALVIN_RS16525	COG4983	Phage plasmid primase, P4 family domain protein
ALVIN_RS16565	COG2205	protein histidine kinase activity
ALVIN_RS16565	COG5002	protein histidine kinase activity
ALVIN_RS16565	COG0784	Response regulator, receiver
ALVIN_RS16580	COG2205	protein histidine kinase activity
ALVIN_RS16580	COG3437	response regulator, receiver
ALVIN_RS16580	COG4999	Histidine kinase
ALVIN_RS16580	COG3850	Histidine kinase
ALVIN_RS16585	COG0784	Response regulator, receiver
ALVIN_RS16585	COG2205	protein histidine kinase activity
ALVIN_RS16585	COG5002	protein histidine kinase activity
ALVIN_RS16595	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ALVIN_RS16615	COG0741	lytic transglycosylase activity
ALVIN_RS16620	COG3409	Peptidoglycan-binding domain 1 protein
ALVIN_RS16620	COG3267	Type II secretory pathway component ExeA
ALVIN_RS16635	COG5001	Diguanylate cyclase
ALVIN_RS16635	COG3706	GGDEF domain
ALVIN_RS16635	COG4251	negative regulation of phosphorylation
ALVIN_RS16635	COG2203	Gaf domain
ALVIN_RS16670	COG2205	protein histidine kinase activity
ALVIN_RS16670	COG5002	protein histidine kinase activity
ALVIN_RS16670	COG0784	Response regulator, receiver
ALVIN_RS16680	COG0784	Response regulator, receiver
ALVIN_RS16680	COG2205	protein histidine kinase activity
ALVIN_RS16680	COG5002	protein histidine kinase activity
ALVIN_RS16685	COG2201	protein-glutamate methylesterase activity
ALVIN_RS16695	COG0840	transmembrane signaling receptor activity
ALVIN_RS16705	COG0784	Response regulator, receiver
ALVIN_RS16705	COG2205	protein histidine kinase activity
ALVIN_RS16705	COG5002	protein histidine kinase activity