locus-tag	class	description
C7Y71_RS00180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y71_RS00200	COG3392	D12 class N6 adenine-specific DNA methyltransferase
C7Y71_RS00215	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7Y71_RS00220	COG0436	Aminotransferase
C7Y71_RS00225	COG0543	2 iron, 2 sulfur cluster binding
C7Y71_RS00230	COG0167	dihydroorotate dehydrogenase activity
C7Y71_RS00255	COG1193	negative regulation of DNA recombination
C7Y71_RS00260	COG1234	tRNA 3'-trailer cleavage
C7Y71_RS00270	COG0138	bifunctional purine biosynthesis protein purh
C7Y71_RS00275	COG1640	4-alpha-glucanotransferase
C7Y71_RS00280	COG0105	UTP biosynthetic process
C7Y71_RS00295	COG3681	Belongs to the UPF0597 family
C7Y71_RS00325	COG1285	pathogenesis
C7Y71_RS00345	COG0072	phenylalanine-tRNA ligase activity
C7Y71_RS00345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7Y71_RS00350	COG0217	transcriptional regulatory protein
C7Y71_RS00365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7Y71_RS00370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7Y71_RS00375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7Y71_RS00395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y71_RS00430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7Y71_RS00435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7Y71_RS00440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7Y71_RS00465	COG0658	competence protein
C7Y71_RS00465	COG2333	competence protein COMEC
C7Y71_RS00470	COG0826	peptidase U32
C7Y71_RS00480	COG0563	adenylate kinase activity
C7Y71_RS00485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7Y71_RS00490	COG1496	oxidoreductase activity
C7Y71_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7Y71_RS00530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7Y71_RS00550	COG1215	transferase activity, transferring glycosyl groups
C7Y71_RS00555	COG0305	Participates in initiation and elongation during chromosome replication
C7Y71_RS00565	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y71_RS00600	COG1418	mRNA catabolic process
C7Y71_RS00630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y71_RS00635	COG1538	Outer membrane efflux protein
C7Y71_RS00645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y71_RS00650	COG0617	tRNA 3'-terminal CCA addition
C7Y71_RS00660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7Y71_RS00685	COG0632	four-way junction helicase activity
C7Y71_RS00695	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7Y71_RS00720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7Y71_RS00725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7Y71_RS00730	COG3956	TIGRFAM MazG family protein
C7Y71_RS00740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7Y71_RS00740	COG0574	Belongs to the PEP-utilizing enzyme family
C7Y71_RS00745	COG1674	ftsk spoiiie
C7Y71_RS00755	COG0492	ferredoxin-NADP+ reductase activity
C7Y71_RS00760	COG0572	uridine kinase
C7Y71_RS00790	COG1530	ribonuclease E activity
C7Y71_RS00795	COG0776	regulation of translation
C7Y71_RS00800	COG0698	ribose 5-phosphate isomerase
C7Y71_RS00805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7Y71_RS00815	COG0629	single-stranded DNA binding
C7Y71_RS00835	COG0336	Belongs to the RNA methyltransferase TrmD family
C7Y71_RS00855	COG0358	DNA primase activity
C7Y71_RS00870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7Y71_RS00880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7Y71_RS00890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7Y71_RS00895	COG0131	Imidazoleglycerol-phosphate dehydratase
C7Y71_RS00905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7Y71_RS00910	COG0194	GDP metabolic process
C7Y71_RS00915	COG1561	YicC-like family, N-terminal region
C7Y71_RS00920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7Y71_RS00950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7Y71_RS00950	COG1333	cytochrome c biogenesis protein
C7Y71_RS00975	COG3487	Iron-regulated protein
C7Y71_RS00985	COG2197	response regulator
C7Y71_RS01010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7Y71_RS01015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7Y71_RS01020	COG0509	glycine decarboxylation via glycine cleavage system
C7Y71_RS01025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7Y71_RS01035	COG0488	(ABC) transporter
C7Y71_RS01040	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7Y71_RS01045	COG0542	response to heat
C7Y71_RS01050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7Y71_RS01055	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C7Y71_RS01060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7Y71_RS01060	COG0517	IMP dehydrogenase activity
C7Y71_RS01065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y71_RS01075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7Y71_RS01080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7Y71_RS01085	COG1592	Rubrerythrin
C7Y71_RS01095	COG0706	membrane insertase activity
C7Y71_RS01100	COG1506	peptidase
C7Y71_RS01100	COG0823	Involved in the tonB-independent uptake of proteins
C7Y71_RS01115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7Y71_RS01120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7Y71_RS01130	COG0750	zinc metalloprotease
C7Y71_RS01135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7Y71_RS01140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7Y71_RS01145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7Y71_RS01160	COG0442	prolyl-tRNA aminoacylation
C7Y71_RS01235	COG0673	inositol 2-dehydrogenase activity
C7Y71_RS01250	COG1136	(ABC) transporter
C7Y71_RS01270	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7Y71_RS01290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7Y71_RS01300	COG0297	glycogen (starch) synthase activity
C7Y71_RS01315	COG0058	SHG alpha-glucan phosphorylase activity
C7Y71_RS01390	COG1078	dGTPase activity
C7Y71_RS01395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7Y71_RS01400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7Y71_RS01405	COG0242	peptide deformylase activity
C7Y71_RS01410	COG3250	beta-galactosidase activity
C7Y71_RS01425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7Y71_RS01425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7Y71_RS01450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7Y71_RS01460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7Y71_RS01470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7Y71_RS01485	COG2871	sodium ion transport
C7Y71_RS01490	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y71_RS01495	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y71_RS01500	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y71_RS01505	COG1805	sodium ion transport
C7Y71_RS01510	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y71_RS01535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7Y71_RS01545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7Y71_RS01550	COG0343	queuine tRNA-ribosyltransferase activity
C7Y71_RS01560	COG0513	Belongs to the DEAD box helicase family
C7Y71_RS01570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7Y71_RS01620	COG1215	transferase activity, transferring glycosyl groups
C7Y71_RS01625	COG0488	(ABC) transporter
C7Y71_RS01635	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7Y71_RS01650	COG0149	triose-phosphate isomerase activity
C7Y71_RS01660	COG0302	gtp cyclohydrolase
C7Y71_RS01675	COG0205	6-phosphofructokinase activity
C7Y71_RS01680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7Y71_RS01695	COG0356	it plays a direct role in the translocation of protons across the membrane
C7Y71_RS01700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7Y71_RS01705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7Y71_RS01710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7Y71_RS01715	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7Y71_RS01720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7Y71_RS01735	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7Y71_RS01745	COG0191	fructose-bisphosphate aldolase activity
C7Y71_RS01750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS01755	COG0525	valine-tRNA ligase activity
C7Y71_RS01760	COG2356	endonuclease I
C7Y71_RS01765	COG2356	endonuclease I
C7Y71_RS01775	COG0602	queuosine metabolic process
C7Y71_RS01785	COG1739	Uncharacterized protein family UPF0029
C7Y71_RS01815	COG1696	Membrane protein involved in D-alanine export
C7Y71_RS01835	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C7Y71_RS01855	COG0488	(ABC) transporter
C7Y71_RS01860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7Y71_RS01870	COG0285	dihydrofolate synthase activity
C7Y71_RS01875	COG1169	isochorismate synthase
C7Y71_RS01880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7Y71_RS01885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7Y71_RS01890	COG0148	phosphopyruvate hydratase activity
C7Y71_RS01900	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7Y71_RS01905	COG0385	Bile acid
C7Y71_RS01925	COG1272	protein, Hemolysin III
C7Y71_RS01940	COG1132	(ABC) transporter
C7Y71_RS01950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7Y71_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7Y71_RS01965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7Y71_RS02000	COG0656	L-ascorbic acid biosynthetic process
C7Y71_RS02005	COG0110	maltose O-acetyltransferase activity
C7Y71_RS02050	COG1979	alcohol dehydrogenase
C7Y71_RS02060	COG0656	L-ascorbic acid biosynthetic process
C7Y71_RS02065	COG4771	TonB-dependent receptor
C7Y71_RS02080	COG3022	response to hydroperoxide
C7Y71_RS02085	COG0778	Nitroreductase
C7Y71_RS02115	COG0737	Belongs to the 5'-nucleotidase family
C7Y71_RS02130	COG3345	alpha-galactosidase
C7Y71_RS02175	COG0539	negative regulation of cytoplasmic translation
C7Y71_RS02205	COG0009	L-threonylcarbamoyladenylate synthase
C7Y71_RS02215	COG0489	protein tyrosine kinase activity
C7Y71_RS02235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7Y71_RS02235	COG0321	lipoyl(octanoyl) transferase activity
C7Y71_RS02240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7Y71_RS02245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7Y71_RS02250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7Y71_RS02275	COG1940	carbohydrate kinase activity
C7Y71_RS02280	COG1760	l-serine dehydratase
C7Y71_RS02285	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7Y71_RS02305	COG2304	oxidoreductase activity
C7Y71_RS02325	COG0714	Associated with various cellular activities
C7Y71_RS02335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7Y71_RS02340	COG1690	Belongs to the RtcB family
C7Y71_RS02350	COG0297	glycogen (starch) synthase activity
C7Y71_RS02370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7Y71_RS02375	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7Y71_RS02380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7Y71_RS02430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7Y71_RS02435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7Y71_RS02475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7Y71_RS02495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7Y71_RS02500	COG1119	ATPase activity
C7Y71_RS02510	COG1757	Na H antiporter
C7Y71_RS02525	COG3591	Belongs to the peptidase S1B family
C7Y71_RS02530	COG0346	lactoylglutathione lyase activity
C7Y71_RS02540	COG0534	Mate efflux family protein
C7Y71_RS02545	COG0564	pseudouridine synthase activity
C7Y71_RS02550	COG3119	arylsulfatase activity
C7Y71_RS02565	COG5492	domain, Protein
C7Y71_RS02610	COG1137	ATPase activity
C7Y71_RS02615	COG0318	PFAM AMP-dependent synthetase and ligase
C7Y71_RS02625	COG0101	tRNA pseudouridine synthase activity
C7Y71_RS02630	COG0359	binds to the 23S rRNA
C7Y71_RS02635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7Y71_RS02640	COG0360	Binds together with S18 to 16S ribosomal RNA
C7Y71_RS02665	COG0024	Methionine aminopeptidase
C7Y71_RS02670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7Y71_RS02675	COG1058	Belongs to the CinA family
C7Y71_RS02675	COG1546	Belongs to the CinA family
C7Y71_RS02680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7Y71_RS02685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7Y71_RS02700	COG0552	protein localization to endoplasmic reticulum
C7Y71_RS02705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7Y71_RS02730	COG1127	ABC transporter
C7Y71_RS02735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7Y71_RS02770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7Y71_RS02775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7Y71_RS02780	COG1160	GTP binding
C7Y71_RS02785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7Y71_RS02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7Y71_RS02805	COG3409	Peptidoglycan-binding domain 1 protein
C7Y71_RS02805	COG0793	Belongs to the peptidase S41A family
C7Y71_RS02810	COG2131	deaminase
C7Y71_RS02815	COG0339	signal peptide processing
C7Y71_RS02830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7Y71_RS02845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7Y71_RS02850	COG0052	Belongs to the universal ribosomal protein uS2 family
C7Y71_RS02855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7Y71_RS02860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7Y71_RS02865	COG3279	Response regulator of the LytR AlgR family
C7Y71_RS02875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7Y71_RS02885	COG1388	LysM domain
C7Y71_RS02885	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7Y71_RS02895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7Y71_RS02900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7Y71_RS02915	COG1522	sequence-specific DNA binding
C7Y71_RS02930	COG0406	alpha-ribazole phosphatase activity
C7Y71_RS02945	COG1132	(ABC) transporter
C7Y71_RS02955	COG0542	response to heat
C7Y71_RS02960	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7Y71_RS02965	COG0481	GTPase activity
C7Y71_RS02970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7Y71_RS02975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7Y71_RS02980	COG0107	imidazoleglycerol-phosphate synthase activity
C7Y71_RS03000	COG0140	phosphoribosyl-ATP diphosphatase activity
C7Y71_RS03000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7Y71_RS03005	COG0527	aspartate kinase activity
C7Y71_RS03010	COG0019	diaminopimelate decarboxylase activity
C7Y71_RS03025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7Y71_RS03035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7Y71_RS03045	COG2755	lipolytic protein G-D-S-L family
C7Y71_RS03045	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7Y71_RS03050	COG1696	Membrane protein involved in D-alanine export
C7Y71_RS03060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7Y71_RS03065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7Y71_RS03070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7Y71_RS03075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7Y71_RS03080	COG0228	four-way junction DNA binding
C7Y71_RS03130	COG0126	phosphoglycerate kinase activity
C7Y71_RS03135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7Y71_RS03150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7Y71_RS03160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C7Y71_RS03195	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7Y71_RS03230	COG0586	Pfam SNARE associated Golgi protein
C7Y71_RS03280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7Y71_RS03285	COG2205	protein histidine kinase activity
C7Y71_RS03290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7Y71_RS03295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7Y71_RS03305	COG0463	Glycosyl transferase, family 2
C7Y71_RS03320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7Y71_RS03355	COG0497	DNA recombination
C7Y71_RS03375	COG0592	DNA-directed DNA polymerase activity
C7Y71_RS03380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7Y71_RS03400	COG0516	GMP reductase activity
C7Y71_RS03400	COG0517	IMP dehydrogenase activity
C7Y71_RS03430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7Y71_RS03450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7Y71_RS03475	COG0424	maF-like protein
C7Y71_RS03480	COG0009	L-threonylcarbamoyladenylate synthase
C7Y71_RS03490	COG3119	arylsulfatase activity
C7Y71_RS03495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7Y71_RS03495	COG0167	dihydroorotate dehydrogenase activity
C7Y71_RS03500	COG0433	COG0433 Predicted ATPase
C7Y71_RS03505	COG3015	lipoprotein NlpE involved in copper resistance
C7Y71_RS03550	COG0443	Heat shock 70 kDa protein
C7Y71_RS03620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7Y71_RS03635	COG4804	nuclease activity
C7Y71_RS03640	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C7Y71_RS03685	COG0733	neurotransmitter:sodium symporter activity
C7Y71_RS03690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7Y71_RS03790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7Y71_RS03795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7Y71_RS03860	COG1074	ATP-dependent DNA helicase activity
C7Y71_RS03915	COG0193	aminoacyl-tRNA hydrolase activity
C7Y71_RS03920	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7Y71_RS03930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7Y71_RS03935	COG1862	Preprotein translocase
C7Y71_RS03970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7Y71_RS03985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7Y71_RS03985	COG2755	lipolytic protein G-D-S-L family
C7Y71_RS03990	COG1216	Glycosyl transferase, family 2
C7Y71_RS03990	COG1442	glycosyl transferase family 8
C7Y71_RS03995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7Y71_RS04010	COG0463	Glycosyl transferase, family 2
C7Y71_RS04030	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y71_RS04040	COG0475	glutathione-regulated potassium exporter activity
C7Y71_RS04070	COG1360	Flagellar Motor Protein
C7Y71_RS04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y71_RS04105	COG4804	nuclease activity
C7Y71_RS04130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7Y71_RS04135	COG0569	domain protein
C7Y71_RS04140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7Y71_RS04165	COG3119	arylsulfatase activity
C7Y71_RS04200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS04205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS04210	COG3119	arylsulfatase activity
C7Y71_RS04215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7Y71_RS04260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7Y71_RS04270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7Y71_RS04285	COG0066	3-isopropylmalate dehydratase activity
C7Y71_RS04300	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7Y71_RS04340	COG0714	Associated with various cellular activities
C7Y71_RS04420	COG0778	Nitroreductase
C7Y71_RS04430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7Y71_RS04515	COG0436	Aminotransferase
C7Y71_RS04520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7Y71_RS04575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y71_RS04610	COG3152	Membrane
C7Y71_RS04615	COG2086	electron transfer activity
C7Y71_RS04620	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7Y71_RS04625	COG1960	acyl-CoA dehydrogenase activity
C7Y71_RS04645	COG2873	o-acetylhomoserine
C7Y71_RS04700	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y71_RS04710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7Y71_RS04715	COG1088	dTDP-glucose 4,6-dehydratase activity
C7Y71_RS04765	COG0534	Mate efflux family protein
C7Y71_RS04770	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7Y71_RS04770	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7Y71_RS04775	COG0792	nuclease activity
C7Y71_RS04780	COG0590	tRNA wobble adenosine to inosine editing
C7Y71_RS04785	COG1668	transmembrane transport
C7Y71_RS04790	COG4152	abc transporter atp-binding protein
C7Y71_RS04800	COG2151	metal-sulfur cluster biosynthetic enzyme
C7Y71_RS04805	COG2003	Belongs to the UPF0758 family
C7Y71_RS04810	COG1216	Glycosyl transferase, family 2
C7Y71_RS04820	COG1183	phosphatidylcholine synthase activity
C7Y71_RS04825	COG0688	phosphatidylethanolamine metabolic process
C7Y71_RS04870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7Y71_RS04875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7Y71_RS04880	COG0713	ATP synthesis coupled electron transport
C7Y71_RS04885	COG0839	Belongs to the complex I subunit 6 family
C7Y71_RS04895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C7Y71_RS04900	COG0649	NAD binding
C7Y71_RS04900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7Y71_RS04905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7Y71_RS04910	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7Y71_RS04915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7Y71_RS04980	COG0515	serine threonine protein kinase
C7Y71_RS04995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7Y71_RS05015	COG0436	Aminotransferase
C7Y71_RS05025	COG0670	Belongs to the BI1 family
C7Y71_RS05030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7Y71_RS05030	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7Y71_RS05035	COG0795	lipopolysaccharide-transporting ATPase activity
C7Y71_RS05045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7Y71_RS05050	COG3250	beta-galactosidase activity
C7Y71_RS05055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7Y71_RS05070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7Y71_RS05075	COG3119	arylsulfatase activity
C7Y71_RS05090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7Y71_RS05110	COG0006	proline dipeptidase activity
C7Y71_RS05120	COG1686	Belongs to the peptidase S11 family
C7Y71_RS05125	COG0641	radical SAM
C7Y71_RS05130	COG0482	sulfurtransferase activity
C7Y71_RS05145	COG0708	Exodeoxyribonuclease III
C7Y71_RS05150	COG0616	signal peptide processing
C7Y71_RS05155	COG1663	tetraacyldisaccharide 4'-kinase activity
C7Y71_RS05165	COG3118	belongs to the thioredoxin family
C7Y71_RS05170	COG0471	metal ion transport
C7Y71_RS05180	COG1185	polyribonucleotide nucleotidyltransferase activity
C7Y71_RS05190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7Y71_RS05205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7Y71_RS05210	COG0589	response to stress
C7Y71_RS05210	COG0475	glutathione-regulated potassium exporter activity
C7Y71_RS05215	COG1136	(ABC) transporter
C7Y71_RS05220	COG2996	Protein conserved in bacteria
C7Y71_RS05225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y71_RS05230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7Y71_RS05235	COG1192	Involved in chromosome partitioning
C7Y71_RS05240	COG1475	DNA binding
C7Y71_RS05250	COG0741	lytic transglycosylase activity
C7Y71_RS05250	COG1388	LysM domain
C7Y71_RS05280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7Y71_RS05335	COG0148	phosphopyruvate hydratase activity
C7Y71_RS05345	COG0719	Fe-S assembly protein
C7Y71_RS05355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7Y71_RS05360	COG0195	Participates in both transcription termination and antitermination
C7Y71_RS05365	COG0779	Required for maturation of 30S ribosomal subunits
C7Y71_RS05380	COG0463	Glycosyl transferase, family 2
C7Y71_RS05390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS05410	COG0138	bifunctional purine biosynthesis protein purh
C7Y71_RS05430	COG0768	penicillin binding
C7Y71_RS05435	COG0772	Belongs to the SEDS family
C7Y71_RS05455	COG0494	nUDIX hydrolase
C7Y71_RS05485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7Y71_RS05490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7Y71_RS05495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y71_RS05500	COG3291	Pkd domain containing protein
C7Y71_RS05500	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS05510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7Y71_RS05515	COG0459	protein refolding
C7Y71_RS05530	COG0037	tRNA processing
C7Y71_RS05535	COG0731	radical SAM domain protein
C7Y71_RS05535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7Y71_RS05560	COG0738	Major facilitator superfamily
C7Y71_RS05565	COG1070	Carbohydrate kinase
C7Y71_RS05600	COG4771	TonB-dependent receptor
C7Y71_RS05610	COG0534	Mate efflux family protein
C7Y71_RS05635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7Y71_RS05655	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y71_RS05670	COG0671	phosphoesterase, PA-phosphatase related
C7Y71_RS05680	COG2985	domain, Protein
C7Y71_RS05680	COG0569	domain protein
C7Y71_RS05695	COG4154	Belongs to the RbsD FucU family
C7Y71_RS05715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7Y71_RS05725	COG5016	pyruvate
C7Y71_RS05725	COG0511	ligase activity, forming carbon-carbon bonds
C7Y71_RS05730	COG1649	PFAM Uncharacterised BCR, COG1649
C7Y71_RS05745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS05785	COG1575	Belongs to the MenA family. Type 1 subfamily
C7Y71_RS05800	COG0438	transferase activity, transferring glycosyl groups
C7Y71_RS05800	COG0297	glycogen (starch) synthase activity
C7Y71_RS05805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7Y71_RS05810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7Y71_RS05825	COG2184	nucleotidyltransferase activity
C7Y71_RS05840	COG1774	PSP1 C-terminal conserved region
C7Y71_RS05845	COG0470	DNA polymerase III
C7Y71_RS05850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7Y71_RS05890	COG1506	peptidase
C7Y71_RS05890	COG0823	Involved in the tonB-independent uptake of proteins
C7Y71_RS05895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7Y71_RS05895	COG0116	Belongs to the methyltransferase superfamily
C7Y71_RS05900	COG0515	serine threonine protein kinase
C7Y71_RS05900	COG2815	serine threonine protein kinase
C7Y71_RS05915	COG3620	sequence-specific DNA binding
C7Y71_RS05935	COG2816	NAD+ diphosphatase activity
C7Y71_RS05950	COG0700	Nucleoside recognition
C7Y71_RS05955	COG1611	Belongs to the LOG family
C7Y71_RS05960	COG0251	oxidation-reduction process
C7Y71_RS05965	COG0335	large ribosomal subunit rRNA binding
C7Y71_RS06000	COG0137	argininosuccinate synthase activity
C7Y71_RS06005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7Y71_RS06015	COG4115	mRNA cleavage
C7Y71_RS06020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7Y71_RS06030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7Y71_RS06035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7Y71_RS06040	COG0165	Argininosuccinate lyase
C7Y71_RS06045	COG1592	Rubrerythrin
C7Y71_RS06045	COG1773	rubredoxin
C7Y71_RS06060	COG2321	neutral zinc metallopeptidase
C7Y71_RS06065	COG0494	nUDIX hydrolase
C7Y71_RS06090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7Y71_RS06095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7Y71_RS06110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7Y71_RS06140	COG0756	dUTP diphosphatase activity
C7Y71_RS06155	COG1401	restriction endodeoxyribonuclease activity
C7Y71_RS06170	COG0463	Glycosyl transferase, family 2
C7Y71_RS06180	COG0501	Belongs to the peptidase M48B family
C7Y71_RS06200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7Y71_RS06205	COG0495	leucyl-tRNA aminoacylation
C7Y71_RS06210	COG4991	sh3 domain protein
C7Y71_RS06215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7Y71_RS06220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7Y71_RS06235	COG0084	hydrolase, TatD family'
C7Y71_RS06240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7Y71_RS06245	COG0594	ribonuclease P activity
C7Y71_RS06265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7Y71_RS06285	COG2137	regulation of response to DNA damage stimulus
C7Y71_RS06295	COG0438	transferase activity, transferring glycosyl groups
C7Y71_RS06305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7Y71_RS06310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7Y71_RS06315	COG0124	histidyl-tRNA synthetase
C7Y71_RS06350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7Y71_RS06370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7Y71_RS06375	COG0545	Peptidyl-prolyl cis-trans isomerase
C7Y71_RS06390	COG0545	Peptidyl-prolyl cis-trans isomerase
C7Y71_RS06410	COG0745	RESPONSE REGULATOR receiver
C7Y71_RS06415	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7Y71_RS06420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7Y71_RS06425	COG1053	succinate dehydrogenase
C7Y71_RS06435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7Y71_RS06460	COG0612	Peptidase, M16
C7Y71_RS06475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7Y71_RS06480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7Y71_RS06500	COG0187	DNA topoisomerase II activity
C7Y71_RS06510	COG0513	Belongs to the DEAD box helicase family
C7Y71_RS06520	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7Y71_RS06535	COG1294	oxidase, subunit
C7Y71_RS06545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7Y71_RS06600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7Y71_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y71_RS06660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7Y71_RS06695	COG2720	vancomycin resistance protein
C7Y71_RS06715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7Y71_RS06720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7Y71_RS06725	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7Y71_RS06730	COG1522	sequence-specific DNA binding
C7Y71_RS06740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7Y71_RS06745	COG2234	aminopeptidase activity
C7Y71_RS06760	COG3426	butyrate kinase activity
C7Y71_RS06765	COG0280	phosphate acetyltransferase
C7Y71_RS06775	COG4974	Belongs to the 'phage' integrase family
C7Y71_RS06790	COG0445	tRNA wobble uridine modification
C7Y71_RS06795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7Y71_RS06800	COG0322	excinuclease ABC activity
C7Y71_RS06805	COG1490	D-aminoacyl-tRNA deacylase activity
C7Y71_RS06810	COG1694	Mazg nucleotide pyrophosphohydrolase
C7Y71_RS06825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7Y71_RS06825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7Y71_RS06840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y71_RS06840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y71_RS06845	COG2890	protein-(glutamine-N5) methyltransferase activity
C7Y71_RS06865	COG1929	Belongs to the glycerate kinase type-1 family
C7Y71_RS06880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7Y71_RS06910	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7Y71_RS06930	COG4974	Belongs to the 'phage' integrase family
C7Y71_RS06940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7Y71_RS06950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7Y71_RS06965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS06970	COG1528	Iron-storage protein
C7Y71_RS06975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7Y71_RS06985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7Y71_RS06990	COG1216	Glycosyl transferase, family 2
C7Y71_RS06995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7Y71_RS07005	COG3475	LICD family
C7Y71_RS07010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7Y71_RS07020	COG1368	sulfuric ester hydrolase activity
C7Y71_RS07025	COG1132	(ABC) transporter
C7Y71_RS07030	COG0328	RNA-DNA hybrid ribonuclease activity
C7Y71_RS07030	COG3341	Caulimovirus viroplasmin
C7Y71_RS07040	COG0018	arginyl-trna synthetase
C7Y71_RS07100	COG1045	serine acetyltransferase
C7Y71_RS07115	COG0590	tRNA wobble adenosine to inosine editing
C7Y71_RS07125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7Y71_RS07130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7Y71_RS07135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7Y71_RS07140	COG1968	undecaprenyl-diphosphatase activity
C7Y71_RS07155	COG2176	DNA-directed DNA polymerase activity
C7Y71_RS07215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7Y71_RS07295	COG0606	chelatase, subunit chli
C7Y71_RS07310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7Y71_RS07315	COG0012	GTP binding
C7Y71_RS07320	COG0471	metal ion transport
C7Y71_RS07350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y71_RS07355	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C7Y71_RS07380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y71_RS07425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7Y71_RS07435	COG2755	lipolytic protein G-D-S-L family
C7Y71_RS07435	COG0657	acetylesterase activity
C7Y71_RS07440	COG0531	amino acid
C7Y71_RS07480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS07495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7Y71_RS07500	COG1166	arginine decarboxylase activity
C7Y71_RS07505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7Y71_RS07515	COG1610	YqeY-like protein
C7Y71_RS07520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7Y71_RS07525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7Y71_RS07540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7Y71_RS07545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7Y71_RS07550	COG1238	metal cluster binding
C7Y71_RS07565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7Y71_RS07570	COG2255	four-way junction helicase activity
C7Y71_RS07575	COG4771	TonB-dependent receptor
C7Y71_RS07590	COG0730	response to heat
C7Y71_RS07625	COG0793	Belongs to the peptidase S41A family
C7Y71_RS07630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7Y71_RS07655	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7Y71_RS07665	COG0519	Catalyzes the synthesis of GMP from XMP
C7Y71_RS07665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7Y71_RS07675	COG0515	serine threonine protein kinase
C7Y71_RS07725	COG1629	transport
C7Y71_RS07725	COG4206	TonB-dependent receptor
C7Y71_RS07740	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
C7Y71_RS07755	COG2244	polysaccharide biosynthetic process
C7Y71_RS07760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7Y71_RS07765	COG0438	transferase activity, transferring glycosyl groups
C7Y71_RS07780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7Y71_RS07800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y71_RS07815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7Y71_RS07825	COG1215	transferase activity, transferring glycosyl groups
C7Y71_RS07830	COG0420	3'-5' exonuclease activity
C7Y71_RS07855	COG2027	D-alanyl-D-alanine carboxypeptidase
C7Y71_RS07870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7Y71_RS07875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7Y71_RS07905	COG0196	riboflavin kinase activity
C7Y71_RS07910	COG1011	Hydrolase
C7Y71_RS07915	COG0826	peptidase U32
C7Y71_RS07945	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C7Y71_RS07950	COG0557	exoribonuclease II activity
C7Y71_RS07955	COG1217	gtp-binding protein TYPA
C7Y71_RS07975	COG0039	L-malate dehydrogenase activity
C7Y71_RS07985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7Y71_RS08010	COG3250	beta-galactosidase activity
C7Y71_RS08020	COG0215	cysteine-tRNA ligase activity
C7Y71_RS08080	COG1595	DNA-templated transcription, initiation
C7Y71_RS08095	COG0631	protein serine/threonine phosphatase activity
C7Y71_RS08130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7Y71_RS08135	COG0793	Belongs to the peptidase S41A family
C7Y71_RS08145	COG3142	Participates in the control of copper homeostasis
C7Y71_RS08225	COG0859	PFAM glycosyl transferase family 9
C7Y71_RS08230	COG0562	UDP-galactopyranose mutase
C7Y71_RS08275	COG0233	cytoplasmic translational termination
C7Y71_RS08280	COG1162	GTPase activity
C7Y71_RS08305	COG0716	FMN binding
C7Y71_RS08315	COG1253	flavin adenine dinucleotide binding
C7Y71_RS08335	COG1373	ATPase (AAA superfamily
C7Y71_RS08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y71_RS08350	COG0156	8-amino-7-oxononanoate synthase activity
C7Y71_RS08355	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
C7Y71_RS08360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7Y71_RS08385	COG2843	Capsule synthesis protein
C7Y71_RS08390	COG1115	amino acid carrier protein
C7Y71_RS08395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7Y71_RS08395	COG1918	ferrous iron import across plasma membrane
C7Y71_RS08435	COG4771	TonB-dependent receptor
C7Y71_RS08455	COG3392	D12 class N6 adenine-specific DNA methyltransferase
C7Y71_RS08475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y71_RS08675	COG1518	maintenance of DNA repeat elements
C7Y71_RS08680	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C7Y71_RS08705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7Y71_RS08720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7Y71_RS08725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C7Y71_RS08750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7Y71_RS08755	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS08760	COG3537	Alpha-1,2-mannosidase
C7Y71_RS08765	COG0793	Belongs to the peptidase S41A family
C7Y71_RS08775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7Y71_RS08780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7Y71_RS08800	COG0084	hydrolase, TatD family'
C7Y71_RS08820	COG4868	Belongs to the UPF0371 family
C7Y71_RS08830	COG1373	ATPase (AAA superfamily
C7Y71_RS08840	COG1649	PFAM Uncharacterised BCR, COG1649
C7Y71_RS08860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7Y71_RS08875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y71_RS08915	COG0210	DNA helicase
C7Y71_RS08920	COG0372	Belongs to the citrate synthase family
C7Y71_RS08935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y71_RS08945	COG0802	atpase or kinase
C7Y71_RS08975	COG0427	acetyl-CoA hydrolase
C7Y71_RS08990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7Y71_RS09000	COG3104	oligopeptide transport
C7Y71_RS09005	COG0268	Binds directly to 16S ribosomal RNA
C7Y71_RS09015	COG1381	Involved in DNA repair and RecF pathway recombination
C7Y71_RS09020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7Y71_RS09025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7Y71_RS09030	COG0454	-acetyltransferase
C7Y71_RS09075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7Y71_RS09090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7Y71_RS09095	COG0719	Fe-S assembly protein
C7Y71_RS09100	COG0396	ATPase activity
C7Y71_RS09115	COG2873	o-acetylhomoserine
C7Y71_RS09125	COG1022	Amp-dependent synthetase and ligase
C7Y71_RS09135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7Y71_RS09150	COG2954	triphosphatase activity
C7Y71_RS09155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C7Y71_RS09185	COG1022	Amp-dependent synthetase and ligase
C7Y71_RS09190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7Y71_RS09205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7Y71_RS09210	COG0772	Belongs to the SEDS family
C7Y71_RS09215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7Y71_RS09220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7Y71_RS09225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7Y71_RS09230	COG0768	penicillin binding
C7Y71_RS09245	COG2001	Belongs to the MraZ family
C7Y71_RS09255	COG4974	Belongs to the 'phage' integrase family
C7Y71_RS09260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7Y71_RS09265	COG0668	transmembrane transport
C7Y71_RS09270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7Y71_RS09340	COG0250	Participates in transcription elongation, termination and antitermination
C7Y71_RS09345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7Y71_RS09355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7Y71_RS09360	COG0222	ribosome binding
C7Y71_RS09365	COG0085	RNA polymerase activity
C7Y71_RS09395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7Y71_RS09400	COG0210	DNA helicase
C7Y71_RS09405	COG0673	inositol 2-dehydrogenase activity
C7Y71_RS09410	COG1966	Carbon starvation protein
C7Y71_RS09445	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7Y71_RS09450	COG0049	tRNA binding
C7Y71_RS09455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7Y71_RS09460	COG0051	transcription antitermination factor activity, RNA binding
C7Y71_RS09465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7Y71_RS09470	COG0088	Forms part of the polypeptide exit tunnel
C7Y71_RS09475	COG0089	rRNA binding
C7Y71_RS09480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7Y71_RS09485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7Y71_RS09490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7Y71_RS09495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7Y71_RS09500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7Y71_RS09505	COG0255	Belongs to the universal ribosomal protein uL29 family
C7Y71_RS09510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7Y71_RS09515	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7Y71_RS09520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7Y71_RS09525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7Y71_RS09530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7Y71_RS09535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7Y71_RS09540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7Y71_RS09545	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7Y71_RS09550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7Y71_RS09555	COG1841	ribosomal large subunit assembly
C7Y71_RS09560	COG0200	Binds to the 23S rRNA
C7Y71_RS09575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7Y71_RS09580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7Y71_RS09585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7Y71_RS09590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7Y71_RS09595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7Y71_RS09600	COG0202	RNA polymerase activity
C7Y71_RS09605	COG0203	ribosomal protein L17
C7Y71_RS09615	COG2814	Major facilitator Superfamily
C7Y71_RS09625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7Y71_RS09625	COG0047	phosphoribosylformylglycinamidine synthase activity
C7Y71_RS09700	COG1373	ATPase (AAA superfamily
C7Y71_RS09730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7Y71_RS09765	COG3620	sequence-specific DNA binding
C7Y71_RS09840	COG1216	Glycosyl transferase, family 2
C7Y71_RS09970	COG4974	Belongs to the 'phage' integrase family
C7Y71_RS10010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7Y71_RS10015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7Y71_RS10020	COG1045	serine acetyltransferase
C7Y71_RS10025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7Y71_RS10035	COG0628	permease
C7Y71_RS10040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7Y71_RS10070	COG4771	TonB-dependent receptor
C7Y71_RS10100	COG2502	aspartate--ammonia ligase
C7Y71_RS10115	COG2211	Major facilitator Superfamily
C7Y71_RS10130	COG1309	transcriptional regulator
C7Y71_RS10150	COG0423	glycine-tRNA ligase activity
C7Y71_RS10210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7Y71_RS10215	COG1366	Belongs to the anti-sigma-factor antagonist family
C7Y71_RS10250	COG1722	exodeoxyribonuclease VII activity
C7Y71_RS10255	COG1570	exodeoxyribonuclease VII activity
C7Y71_RS10265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7Y71_RS10280	COG0811	peptide transport
C7Y71_RS10285	COG0848	biopolymer transport protein
C7Y71_RS10310	COG0673	inositol 2-dehydrogenase activity
C7Y71_RS10330	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7Y71_RS10335	COG2815	serine threonine protein kinase
C7Y71_RS10335	COG0515	serine threonine protein kinase
C7Y71_RS10340	COG0564	pseudouridine synthase activity
C7Y71_RS10345	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7Y71_RS10370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7Y71_RS10405	COG1215	transferase activity, transferring glycosyl groups
C7Y71_RS10430	COG0438	transferase activity, transferring glycosyl groups
C7Y71_RS10455	COG1442	glycosyl transferase family 8
C7Y71_RS10455	COG1216	Glycosyl transferase, family 2
C7Y71_RS10460	COG1216	Glycosyl transferase, family 2
C7Y71_RS10465	COG0110	maltose O-acetyltransferase activity
C7Y71_RS10470	COG0297	glycogen (starch) synthase activity
C7Y71_RS10490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7Y71_RS10520	COG1596	polysaccharide export
C7Y71_RS10525	COG0436	Aminotransferase
C7Y71_RS10530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7Y71_RS10535	COG0504	CTP synthase activity
C7Y71_RS10540	COG0367	asparagine synthase
C7Y71_RS10550	COG0737	Belongs to the 5'-nucleotidase family
C7Y71_RS10555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7Y71_RS10560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7Y71_RS10565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C7Y71_RS10570	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7Y71_RS10570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7Y71_RS10575	COG2264	protein methyltransferase activity
C7Y71_RS10585	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7Y71_RS10595	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7Y71_RS10610	COG1196	nuclear chromosome segregation
C7Y71_RS10615	COG0598	Magnesium transport protein CorA
C7Y71_RS10625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7Y71_RS10650	COG0514	ATP-dependent DNA helicase (RecQ)
C7Y71_RS10655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7Y71_RS10655	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7Y71_RS10660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7Y71_RS10670	COG0386	Belongs to the glutathione peroxidase family
C7Y71_RS10675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7Y71_RS10680	COG1943	Transposase
C7Y71_RS10695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7Y71_RS10705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7Y71_RS10720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7Y71_RS10750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7Y71_RS10755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7Y71_RS10760	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C7Y71_RS10765	COG0540	Belongs to the ATCase OTCase family
C7Y71_RS10770	COG0352	thiamine-phosphate diphosphorylase activity
C7Y71_RS10790	COG2204	response regulator
C7Y71_RS10805	COG0778	Nitroreductase
C7Y71_RS10815	COG0129	dihydroxy-acid dehydratase activity
C7Y71_RS10820	COG0028	Belongs to the TPP enzyme family
C7Y71_RS10830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7Y71_RS10850	COG3177	Filamentation induced by cAMP protein fic
C7Y71_RS10870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7Y71_RS10910	COG0494	nUDIX hydrolase
C7Y71_RS10915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7Y71_RS10920	COG2226	methyltransferase
C7Y71_RS10925	COG0363	glucosamine-6-phosphate deaminase activity
C7Y71_RS10930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7Y71_RS10930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7Y71_RS10935	COG1597	lipid kinase activity
C7Y71_RS10940	COG0156	8-amino-7-oxononanoate synthase activity
C7Y71_RS10945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7Y71_RS10970	COG0542	response to heat
C7Y71_RS10990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7Y71_RS10995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7Y71_RS11000	COG1595	DNA-templated transcription, initiation
C7Y71_RS11005	COG1242	4 iron, 4 sulfur cluster binding
C7Y71_RS11015	COG4206	TonB-dependent receptor
C7Y71_RS11015	COG1629	transport
C7Y71_RS11035	COG4771	TonB-dependent receptor
C7Y71_RS11045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y71_RS11050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7Y71_RS11050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7Y71_RS11065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7Y71_RS11070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7Y71_RS11075	COG1702	phosphate starvation-inducible protein PhoH
C7Y71_RS11080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7Y71_RS11090	COG0463	Glycosyl transferase, family 2
C7Y71_RS11105	COG1477	protein flavinylation
C7Y71_RS11120	COG2217	Heavy metal translocating P-type atpase
C7Y71_RS11130	COG1970	mechanosensitive ion channel activity
C7Y71_RS11145	COG2971	BadF BadG BcrA BcrD
C7Y71_RS11155	COG3757	hydrolase, family 25
C7Y71_RS11175	COG1187	pseudouridine synthase activity
C7Y71_RS11180	COG0017	Asparaginyl-tRNA synthetase
C7Y71_RS11190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7Y71_RS11225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7Y71_RS11230	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7Y71_RS11245	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7Y71_RS11250	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7Y71_RS11255	COG0740	serine-type endopeptidase activity
C7Y71_RS11260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7Y71_RS11270	COG0488	(ABC) transporter
C7Y71_RS11275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7Y71_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7Y71_RS11305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7Y71_RS11310	COG0799	negative regulation of ribosome biogenesis
C7Y71_RS11315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7Y71_RS11320	COG0280	phosphate acetyltransferase
C7Y71_RS11330	COG0528	UMP kinase activity
C7Y71_RS11335	COG1482	cell wall glycoprotein biosynthetic process
C7Y71_RS11385	COG0295	cytidine deaminase activity
C7Y71_RS11400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7Y71_RS11400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7Y71_RS11410	COG1120	ATPase activity
C7Y71_RS11420	COG3119	arylsulfatase activity
C7Y71_RS11435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7Y71_RS11440	COG0463	Glycosyl transferase, family 2
C7Y71_RS11455	COG1002	Type II restriction enzyme, methylase subunits
C7Y71_RS11470	COG3590	peptidase
C7Y71_RS11475	COG1227	inorganic diphosphatase activity
C7Y71_RS11480	COG1472	Belongs to the glycosyl hydrolase 3 family
C7Y71_RS11490	COG0254	rRNA binding
C7Y71_RS11495	COG0673	inositol 2-dehydrogenase activity
C7Y71_RS11500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7Y71_RS11515	COG1253	flavin adenine dinucleotide binding
C7Y71_RS11525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7Y71_RS11545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C7Y71_RS11560	COG0166	Belongs to the GPI family
C7Y71_RS11565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7Y71_RS11580	COG0653	protein targeting
C7Y71_RS11590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7Y71_RS11610	COG0543	2 iron, 2 sulfur cluster binding
C7Y71_RS11630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7Y71_RS11635	COG0357	Ribosomal RNA small subunit methyltransferase G
C7Y71_RS11645	COG1032	radical SAM domain protein
C7Y71_RS11715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))