locus-tag	class	description
AEB_RS00025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEB_RS00035	COG1301	dicarboxylic acid transport
AEB_RS00040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEB_RS00045	COG0625	glutathione transferase activity
AEB_RS00065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AEB_RS00070	COG0706	membrane insertase activity
AEB_RS00075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AEB_RS00080	COG0594	ribonuclease P activity
AEB_RS00085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AEB_RS00135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEB_RS00210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AEB_RS00225	COG2866	Carboxypeptidase
AEB_RS00235	COG0753	catalase activity
AEB_RS00265	COG5328	Belongs to the UPF0262 family
AEB_RS00270	COG0305	Participates in initiation and elongation during chromosome replication
AEB_RS00280	COG1758	RNA polymerase activity
AEB_RS00285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_RS00290	COG2894	cell division
AEB_RS00325	COG1482	cell wall glycoprotein biosynthetic process
AEB_RS00355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AEB_RS00435	COG0489	protein tyrosine kinase activity
AEB_RS00435	COG3206	protein involved in exopolysaccharide biosynthesis
AEB_RS00455	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AEB_RS00485	COG1045	serine acetyltransferase
AEB_RS00490	COG2755	lipolytic protein G-D-S-L family
AEB_RS00490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEB_RS00510	COG0673	inositol 2-dehydrogenase activity
AEB_RS00515	COG0730	response to heat
AEB_RS00520	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEB_RS00530	COG0175	sulfate reduction
AEB_RS00555	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AEB_RS00560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS00565	COG3453	Protein conserved in bacteria
AEB_RS00565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_RS00570	COG0450	alkyl hydroperoxide reductase
AEB_RS00595	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEB_RS00615	COG3447	MASE1 domain protein
AEB_RS00615	COG5002	protein histidine kinase activity
AEB_RS00615	COG5001	Diguanylate cyclase
AEB_RS00620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_RS00625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AEB_RS00630	COG4988	ABC transporter
AEB_RS00640	COG1294	oxidase, subunit
AEB_RS00660	COG4771	TonB-dependent receptor
AEB_RS00685	COG1609	Transcriptional regulator
AEB_RS00700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEB_RS00705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEB_RS00720	COG2188	Transcriptional regulator
AEB_RS00735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_RS00755	COG1414	Transcriptional regulator
AEB_RS00780	COG0402	S-adenosylhomocysteine deaminase activity
AEB_RS00785	COG4771	TonB-dependent receptor
AEB_RS00840	COG0384	phenazine biosynthesis protein PhzF
AEB_RS00870	COG0596	Alpha beta hydrolase
AEB_RS00880	COG2318	DinB family
AEB_RS00955	COG0702	epimerase
AEB_RS00960	COG2133	pyrroloquinoline quinone binding
AEB_RS00965	COG1217	gtp-binding protein TYPA
AEB_RS00980	COG3618	amidohydrolase
AEB_RS00990	COG1372	Participates in initiation and elongation during chromosome replication
AEB_RS00990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEB_RS01005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEB_RS01005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEB_RS01015	COG2827	Endonuclease containing a URI domain
AEB_RS01025	COG1131	(ABC) transporter
AEB_RS01060	COG0469	pyruvate kinase activity
AEB_RS01070	COG3750	Belongs to the UPF0335 family
AEB_RS01075	COG0393	Putative heavy-metal-binding
AEB_RS01080	COG0217	transcriptional regulatory protein
AEB_RS01085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AEB_RS01095	COG1393	Belongs to the ArsC family
AEB_RS01100	COG3781	membrane
AEB_RS01105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEB_RS01110	COG0527	aspartate kinase activity
AEB_RS01120	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS01130	COG2119	membrane
AEB_RS01140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_RS01150	COG2175	clavaminate synthase activity
AEB_RS01155	COG1063	alcohol dehydrogenase
AEB_RS01175	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS01180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AEB_RS01250	COG2159	amidohydrolase
AEB_RS01260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AEB_RS01305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEB_RS01320	COG2095	MarC family integral membrane protein
AEB_RS01325	COG3920	Histidine kinase
AEB_RS01340	COG3118	belongs to the thioredoxin family
AEB_RS01370	COG0300	oxidoreductase activity
AEB_RS01380	COG0519	Catalyzes the synthesis of GMP from XMP
AEB_RS01380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEB_RS01405	COG0129	dihydroxy-acid dehydratase activity
AEB_RS01410	COG0445	tRNA wobble uridine modification
AEB_RS01435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEB_RS01450	COG1960	acyl-CoA dehydrogenase activity
AEB_RS01460	COG0517	IMP dehydrogenase activity
AEB_RS01460	COG1125	glycine betaine transport
AEB_RS01465	COG1174	glycine betaine transport
AEB_RS01475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AEB_RS01480	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AEB_RS01500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEB_RS01510	COG1674	ftsk spoiiie
AEB_RS01525	COG4771	TonB-dependent receptor
AEB_RS01540	COG0686	Belongs to the AlaDH PNT family
AEB_RS01580	COG2205	protein histidine kinase activity
AEB_RS01590	COG0433	COG0433 Predicted ATPase
AEB_RS01605	COG0564	pseudouridine synthase activity
AEB_RS01615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEB_RS01665	COG3186	Phenylalanine-4-hydroxylase
AEB_RS01675	COG1968	undecaprenyl-diphosphatase activity
AEB_RS01680	COG3590	peptidase
AEB_RS01685	COG1132	(ABC) transporter
AEB_RS01710	COG0070	glutamate synthase
AEB_RS01710	COG0069	glutamate synthase activity
AEB_RS01710	COG0067	glutamate synthase
AEB_RS01730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AEB_RS01750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEB_RS01755	COG2957	Belongs to the agmatine deiminase family
AEB_RS01760	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AEB_RS01765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEB_RS01770	COG2833	Protein of unknown function (DUF455)
AEB_RS01775	COG0739	heme binding
AEB_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS01815	COG0495	leucyl-tRNA aminoacylation
AEB_RS01840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AEB_RS01845	COG2902	Dehydrogenase
AEB_RS01855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEB_RS01860	COG4152	abc transporter atp-binding protein
AEB_RS01870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_RS01895	COG0776	regulation of translation
AEB_RS01900	COG2188	Transcriptional regulator
AEB_RS01905	COG3104	oligopeptide transport
AEB_RS01910	COG1228	amidohydrolase
AEB_RS01920	COG0545	Peptidyl-prolyl cis-trans isomerase
AEB_RS01925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEB_RS01935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_RS01970	COG1473	amidohydrolase
AEB_RS01980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEB_RS02040	COG5489	Protein of unknown function (DUF736)
AEB_RS02055	COG0776	regulation of translation
AEB_RS02110	COG0741	lytic transglycosylase activity
AEB_RS02130	COG4962	Type ii secretion system protein e
AEB_RS02145	COG3451	type IV secretory pathway VirB4
AEB_RS02195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEB_RS02195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEB_RS02200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_RS02215	COG0640	Transcriptional regulator
AEB_RS02220	COG0450	alkyl hydroperoxide reductase
AEB_RS02245	COG0730	response to heat
AEB_RS02250	COG0450	alkyl hydroperoxide reductase
AEB_RS02255	COG1271	oxidase subunit
AEB_RS02260	COG1294	oxidase, subunit
AEB_RS02270	COG2226	methyltransferase
AEB_RS02285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AEB_RS02295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS02315	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AEB_RS02320	COG1088	dTDP-glucose 4,6-dehydratase activity
AEB_RS02325	COG1091	dTDP-4-dehydrorhamnose reductase activity
AEB_RS02330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AEB_RS02365	COG0438	transferase activity, transferring glycosyl groups
AEB_RS02365	COG1216	Glycosyl transferase, family 2
AEB_RS02445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEB_RS02450	COG2857	Cytochrome c1
AEB_RS02450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AEB_RS02465	COG1496	oxidoreductase activity
AEB_RS02470	COG0308	aminopeptidase N
AEB_RS02520	COG0588	phosphoglycerate mutase activity
AEB_RS02530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AEB_RS02540	COG0196	riboflavin kinase activity
AEB_RS02545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AEB_RS02550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEB_RS02565	COG1253	flavin adenine dinucleotide binding
AEB_RS02570	COG2885	chlorophyll binding
AEB_RS02575	COG1218	3'(2'),5'-bisphosphate nucleotidase
AEB_RS02580	COG0045	succinate-CoA ligase (ADP-forming) activity
AEB_RS02590	COG2086	electron transfer activity
AEB_RS02610	COG2733	membrane
AEB_RS02620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS02635	COG0482	sulfurtransferase activity
AEB_RS02660	COG0259	pyridoxamine-phosphate oxidase activity
AEB_RS02665	COG0484	heat shock protein binding
AEB_RS02670	COG1295	ribonuclease BN
AEB_RS02675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AEB_RS02685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEB_RS02705	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AEB_RS02715	COG0793	Belongs to the peptidase S41A family
AEB_RS02725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AEB_RS02730	COG0799	negative regulation of ribosome biogenesis
AEB_RS02735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEB_RS02740	COG0667	Aldo Keto reductase
AEB_RS02745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AEB_RS02750	COG0739	heme binding
AEB_RS02765	COG0438	transferase activity, transferring glycosyl groups
AEB_RS02780	COG0604	alcohol dehydrogenase
AEB_RS02795	COG1793	dna ligase
AEB_RS02795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEB_RS02805	COG1872	DUF167
AEB_RS02810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AEB_RS02820	COG0113	porphobilinogen synthase activity
AEB_RS02825	COG0739	heme binding
AEB_RS02840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AEB_RS02845	COG1329	Transcriptional regulator
AEB_RS02875	COG1956	GAF domain-containing protein
AEB_RS02895	COG0357	Ribosomal RNA small subunit methyltransferase G
AEB_RS02900	COG0445	tRNA wobble uridine modification
AEB_RS02905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AEB_RS02920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AEB_RS02925	COG1981	membrane
AEB_RS02930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AEB_RS02935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AEB_RS02940	COG0424	maF-like protein
AEB_RS02945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEB_RS02950	COG0237	dephospho-CoA kinase activity
AEB_RS02960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AEB_RS02965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_RS02990	COG0316	Belongs to the HesB IscA family
AEB_RS02995	COG0517	IMP dehydrogenase activity
AEB_RS03020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEB_RS03025	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AEB_RS03025	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AEB_RS03030	COG2972	Histidine kinase
AEB_RS03060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEB_RS03065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEB_RS03075	COG1612	heme a metabolic process
AEB_RS03085	COG2022	thiamine diphosphate biosynthetic process
AEB_RS03095	COG1022	Amp-dependent synthetase and ligase
AEB_RS03100	COG0405	Gamma-glutamyltransferase
AEB_RS03105	COG0167	dihydroorotate dehydrogenase activity
AEB_RS03110	COG1959	2 iron, 2 sulfur cluster binding
AEB_RS03115	COG0719	Fe-S assembly protein
AEB_RS03125	COG0396	ATPase activity
AEB_RS03130	COG0719	Fe-S assembly protein
AEB_RS03140	COG2151	metal-sulfur cluster biosynthetic enzyme
AEB_RS03145	COG0316	Belongs to the HesB IscA family
AEB_RS03170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AEB_RS03175	COG0151	Belongs to the GarS family
AEB_RS03180	COG1570	exodeoxyribonuclease VII activity
AEB_RS03200	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEB_RS03205	COG0590	tRNA wobble adenosine to inosine editing
AEB_RS03230	COG3275	phosphorelay sensor kinase activity
AEB_RS03240	COG0501	Belongs to the peptidase M48B family
AEB_RS03295	COG2205	protein histidine kinase activity
AEB_RS03305	COG0659	secondary active sulfate transmembrane transporter activity
AEB_RS03320	COG4251	negative regulation of phosphorylation
AEB_RS03325	COG4774	siderophore transport
AEB_RS03335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AEB_RS03340	COG1192	Involved in chromosome partitioning
AEB_RS03345	COG0484	heat shock protein binding
AEB_RS03385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AEB_RS03385	COG0517	IMP dehydrogenase activity
AEB_RS03390	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AEB_RS03415	COG3665	Urea carboxylase-associated protein
AEB_RS03425	COG1201	RNA secondary structure unwinding
AEB_RS03465	COG1494	fructose-1,6-bisphosphatase
AEB_RS03490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AEB_RS03495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEB_RS03505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEB_RS03510	COG0072	phenylalanine-tRNA ligase activity
AEB_RS03515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AEB_RS03530	COG0347	Belongs to the P(II) protein family
AEB_RS03535	COG0004	ammonium transporteR
AEB_RS03540	COG2885	chlorophyll binding
AEB_RS03540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AEB_RS03550	COG1253	flavin adenine dinucleotide binding
AEB_RS03555	COG1278	Cold shock
AEB_RS03560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEB_RS03565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEB_RS03580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AEB_RS03655	COG4695	Portal protein
AEB_RS03680	COG0156	8-amino-7-oxononanoate synthase activity
AEB_RS03685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEB_RS03745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEB_RS03760	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_RS03775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_RS03785	COG0281	malic enzyme
AEB_RS03785	COG0280	phosphate acetyltransferase
AEB_RS03815	COG1475	DNA binding
AEB_RS03820	COG2226	methyltransferase
AEB_RS03830	COG4227	nucleotidyltransferase activity
AEB_RS03910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_RS03915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEB_RS03915	COG2010	Cytochrome c
AEB_RS03960	COG0672	)-iron permease
AEB_RS03980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEB_RS04035	COG2217	Heavy metal translocating P-type atpase
AEB_RS04075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEB_RS04080	COG0713	ATP synthesis coupled electron transport
AEB_RS04090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEB_RS04100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_RS04150	COG0741	lytic transglycosylase activity
AEB_RS04205	COG4962	Type ii secretion system protein e
AEB_RS04220	COG3451	type IV secretory pathway VirB4
AEB_RS04240	COG3701	Conjugal transfer protein
AEB_RS04250	COG2948	multi-organism process
AEB_RS04270	COG1506	peptidase
AEB_RS04270	COG0823	Involved in the tonB-independent uptake of proteins
AEB_RS04275	COG4771	TonB-dependent receptor
AEB_RS04295	COG2771	luxR family
AEB_RS04310	COG1802	Transcriptional regulator
AEB_RS04330	COG0640	Transcriptional regulator
AEB_RS04360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AEB_RS04370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AEB_RS04375	COG1137	ATPase activity
AEB_RS04385	COG0668	transmembrane transport
AEB_RS04390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEB_RS04400	COG0124	histidyl-tRNA synthetase
AEB_RS04405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEB_RS04410	COG2890	protein-(glutamine-N5) methyltransferase activity
AEB_RS04420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AEB_RS04425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEB_RS04430	COG2311	Membrane
AEB_RS04435	COG0477	Major facilitator Superfamily
AEB_RS04455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEB_RS04465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEB_RS04465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEB_RS04485	COG0459	protein refolding
AEB_RS04490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEB_RS04495	COG0534	Mate efflux family protein
AEB_RS04505	COG0222	ribosome binding
AEB_RS04510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AEB_RS04525	COG0085	RNA polymerase activity
AEB_RS04530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AEB_RS04535	COG1902	pentaerythritol trinitrate reductase activity
AEB_RS04540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AEB_RS04540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_RS04555	COG0717	Belongs to the dCTP deaminase family
AEB_RS04565	COG0028	Belongs to the TPP enzyme family
AEB_RS04570	COG0643	Histidine kinase
AEB_RS04570	COG0784	Response regulator, receiver
AEB_RS04570	COG2198	Histidine kinase
AEB_RS04580	COG0745	RESPONSE REGULATOR receiver
AEB_RS04585	COG2201	protein-glutamate methylesterase activity
AEB_RS04590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEB_RS04595	COG5001	Diguanylate cyclase
AEB_RS04600	COG0840	transmembrane signaling receptor activity
AEB_RS04610	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_RS04620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_RS04625	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS04630	COG3038	cytochrome b561
AEB_RS04635	COG1741	Belongs to the pirin family
AEB_RS04640	COG0668	transmembrane transport
AEB_RS04645	COG4771	TonB-dependent receptor
AEB_RS04650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEB_RS04655	COG0346	lactoylglutathione lyase activity
AEB_RS04690	COG0668	transmembrane transport
AEB_RS04705	COG2884	Cell division ATP-binding protein ftsE
AEB_RS04725	COG0287	Prephenate dehydrogenase
AEB_RS04730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEB_RS04735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_RS04740	COG2813	Specifically methylates the guanine in position
AEB_RS04740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_RS04745	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AEB_RS04755	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AEB_RS04765	COG3383	formate dehydrogenase (NAD+) activity
AEB_RS04785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AEB_RS04800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AEB_RS04805	COG2814	Major facilitator Superfamily
AEB_RS04850	COG2814	Major facilitator Superfamily
AEB_RS04855	COG0702	epimerase
AEB_RS04870	COG2271	Major facilitator Superfamily
AEB_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS04905	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AEB_RS04930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_RS04935	COG2267	carboxylic ester hydrolase activity
AEB_RS04940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEB_RS04945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AEB_RS04950	COG1546	Belongs to the CinA family
AEB_RS04950	COG1058	Belongs to the CinA family
AEB_RS04960	COG0081	regulation of translation
AEB_RS04965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEB_RS04990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEB_RS04995	COG1115	amino acid carrier protein
AEB_RS05005	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AEB_RS05030	COG0318	PFAM AMP-dependent synthetase and ligase
AEB_RS05060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_RS05085	COG2205	protein histidine kinase activity
AEB_RS05105	COG3706	GGDEF domain
AEB_RS05110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AEB_RS05120	COG0457	Tetratricopeptide repeat
AEB_RS05140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEB_RS05140	COG2111	Na H antiporter
AEB_RS05145	COG1006	Multisubunit Na H antiporter MnhC subunit
AEB_RS05150	COG0651	ATP synthesis coupled electron transport
AEB_RS05160	COG2212	antiporter activity
AEB_RS05195	COG1741	Belongs to the pirin family
AEB_RS05215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AEB_RS05215	COG0662	Cupin 2, conserved barrel domain protein
AEB_RS05235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEB_RS05240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_RS05240	COG2010	Cytochrome c
AEB_RS05245	COG0489	protein tyrosine kinase activity
AEB_RS05250	COG0330	HflC and HflK could
AEB_RS05265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEB_RS05270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEB_RS05280	COG1846	Transcriptional regulator
AEB_RS05290	COG0477	Major facilitator Superfamily
AEB_RS05320	COG2852	Protein conserved in bacteria
AEB_RS05360	COG0657	acetylesterase activity
AEB_RS05375	COG0248	Ppx GppA phosphatase
AEB_RS05380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEB_RS05385	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AEB_RS05405	COG3451	type IV secretory pathway VirB4
AEB_RS05420	COG1196	nuclear chromosome segregation
AEB_RS05420	COG0741	lytic transglycosylase activity
AEB_RS05420	COG0739	heme binding
AEB_RS05460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEB_RS05465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AEB_RS05500	COG4993	Dehydrogenase
AEB_RS05510	COG0307	riboflavin synthase, alpha
AEB_RS05515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEB_RS05515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEB_RS05520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AEB_RS05525	COG0659	secondary active sulfate transmembrane transporter activity
AEB_RS05540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_RS05555	COG3659	wide pore channel activity
AEB_RS05560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEB_RS05560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AEB_RS05565	COG1105	Belongs to the carbohydrate kinase PfkB family
AEB_RS05570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_RS05570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_RS05575	COG1609	Transcriptional regulator
AEB_RS05580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEB_RS05585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEB_RS05600	COG1448	Aminotransferase
AEB_RS05620	COG2983	Belongs to the UPF0260 family
AEB_RS05625	COG1999	signal sequence binding
AEB_RS05650	COG0629	single-stranded DNA binding
AEB_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS05660	COG1733	regulation of RNA biosynthetic process
AEB_RS05680	COG0583	DNA-binding transcription factor activity
AEB_RS05715	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AEB_RS05720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AEB_RS05740	COG5265	(ABC) transporter
AEB_RS05795	COG2081	HI0933 family
AEB_RS05805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEB_RS05815	COG0114	fumarate hydratase activity
AEB_RS05835	COG4122	O-methyltransferase activity
AEB_RS05840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEB_RS05855	COG1024	Enoyl-CoA hydratase
AEB_RS05900	COG2376	Dihydroxyacetone kinase
AEB_RS05910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEB_RS05925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEB_RS05930	COG1120	ATPase activity
AEB_RS05970	COG2824	Alkylphosphonate utilization operon protein PhnA
AEB_RS05990	COG4106	trans-aconitate 2-methyltransferase activity
AEB_RS06030	COG0477	Major facilitator Superfamily
AEB_RS06035	COG0436	Aminotransferase
AEB_RS06040	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEB_RS06050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AEB_RS06080	COG0784	Response regulator, receiver
AEB_RS06090	COG1063	alcohol dehydrogenase
AEB_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS06120	COG4977	sequence-specific DNA binding
AEB_RS06125	COG2271	Major facilitator Superfamily
AEB_RS06135	COG0235	Class ii aldolase
AEB_RS06140	COG2080	2 iron, 2 sulfur cluster binding
AEB_RS06160	COG0321	lipoyl(octanoyl) transferase activity
AEB_RS06235	COG0037	tRNA processing
AEB_RS06250	COG0800	Aldolase
AEB_RS06255	COG0837	glucose binding
AEB_RS06260	COG0129	dihydroxy-acid dehydratase activity
AEB_RS06265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AEB_RS06275	COG0432	Pfam Uncharacterised protein family UPF0047
AEB_RS06300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_RS06315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AEB_RS06320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEB_RS06345	COG4206	TonB-dependent receptor
AEB_RS06350	COG4251	negative regulation of phosphorylation
AEB_RS06350	COG3706	GGDEF domain
AEB_RS06350	COG2203	Gaf domain
AEB_RS06350	COG5001	Diguanylate cyclase
AEB_RS06355	COG3706	GGDEF domain
AEB_RS06360	COG4566	intracellular signal transduction
AEB_RS06370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AEB_RS06380	COG1684	flagellar biosynthetic protein fliR
AEB_RS06385	COG1987	bacterial-type flagellum assembly
AEB_RS06425	COG1157	protein secretion by the type III secretion system
AEB_RS06435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AEB_RS06445	COG1677	Flagellar hook-basal body complex protein FliE
AEB_RS06455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEB_RS06475	COG1360	Flagellar Motor Protein
AEB_RS06485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AEB_RS06490	COG1256	bacterial-type flagellum assembly
AEB_RS06490	COG4786	Flagellar basal body rod
AEB_RS06500	COG1706	bacterial-type flagellum-dependent cell motility
AEB_RS06505	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AEB_RS06520	COG4786	Flagellar basal body rod
AEB_RS06540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AEB_RS06585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS06605	COG0842	Transport permease protein
AEB_RS06610	COG0842	Transport permease protein
AEB_RS06615	COG1131	(ABC) transporter
AEB_RS06625	COG1309	transcriptional regulator
AEB_RS06630	COG0577	efflux transmembrane transporter activity
AEB_RS06630	COG1136	(ABC) transporter
AEB_RS06635	COG0577	efflux transmembrane transporter activity
AEB_RS06635	COG1136	(ABC) transporter
AEB_RS06640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS06650	COG1846	Transcriptional regulator
AEB_RS06670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEB_RS06675	COG4770	biotin carboxylase activity
AEB_RS06680	COG3755	Protein conserved in bacteria
AEB_RS06685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEB_RS06695	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEB_RS06695	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEB_RS06700	COG0346	lactoylglutathione lyase activity
AEB_RS06720	COG0439	Biotin carboxylase
AEB_RS06725	COG0511	ligase activity, forming carbon-carbon bonds
AEB_RS06750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AEB_RS06770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEB_RS06780	COG1024	Enoyl-CoA hydratase
AEB_RS06795	COG1960	acyl-CoA dehydrogenase activity
AEB_RS06820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEB_RS06825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AEB_RS06830	COG0181	hydroxymethylbilane synthase activity
AEB_RS06845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEB_RS06860	COG0556	nucleotide-excision repair
AEB_RS06870	COG2226	methyltransferase
AEB_RS06870	COG0596	Alpha beta hydrolase
AEB_RS06870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_RS06875	COG2308	Evidence 4 Homologs of previously reported genes of
AEB_RS06905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEB_RS06910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEB_RS06915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AEB_RS06930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEB_RS06945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_RS06950	COG0165	Argininosuccinate lyase
AEB_RS06960	COG0019	diaminopimelate decarboxylase activity
AEB_RS06965	COG1648	precorrin-2 dehydrogenase activity
AEB_RS06965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEB_RS06970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AEB_RS06980	COG0628	permease
AEB_RS06985	COG0681	Belongs to the peptidase S26 family
AEB_RS06990	COG0736	holo-[acyl-carrier-protein] synthase activity
AEB_RS06995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AEB_RS07000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AEB_RS07005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEB_RS07005	COG1565	acr, cog1565
AEB_RS07010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_RS07015	COG0109	protoheme IX farnesyltransferase activity
AEB_RS07020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AEB_RS07055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEB_RS07065	COG0314	molybdopterin synthase activity
AEB_RS07075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEB_RS07080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEB_RS07090	COG0354	folic acid binding
AEB_RS07095	COG4251	negative regulation of phosphorylation
AEB_RS07095	COG3706	GGDEF domain
AEB_RS07095	COG5001	Diguanylate cyclase
AEB_RS07095	COG2203	Gaf domain
AEB_RS07105	COG0418	dihydroorotase activity
AEB_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS07130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AEB_RS07150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEB_RS07160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AEB_RS07165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEB_RS07180	COG0789	Transcriptional regulator
AEB_RS07195	COG1196	nuclear chromosome segregation
AEB_RS07200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AEB_RS07200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEB_RS07225	COG1278	Cold shock
AEB_RS07240	COG2816	NAD+ diphosphatase activity
AEB_RS07275	COG2239	Acts as a magnesium transporter
AEB_RS07290	COG0583	DNA-binding transcription factor activity
AEB_RS07295	COG1253	flavin adenine dinucleotide binding
AEB_RS07300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AEB_RS07315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_RS07330	COG4957	zinc ion binding
AEB_RS07350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AEB_RS07355	COG0612	Peptidase, M16
AEB_RS07360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AEB_RS07370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_RS07375	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AEB_RS07390	COG4771	TonB-dependent receptor
AEB_RS07405	COG4774	siderophore transport
AEB_RS07415	COG1477	protein flavinylation
AEB_RS07460	COG2010	Cytochrome c
AEB_RS07495	COG0625	glutathione transferase activity
AEB_RS07505	COG0435	Glutathione S-transferase
AEB_RS07525	COG1054	Belongs to the UPF0176 family
AEB_RS07530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEB_RS07545	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AEB_RS07570	COG1381	Involved in DNA repair and RecF pathway recombination
AEB_RS07575	COG0473	3-isopropylmalate dehydrogenase activity
AEB_RS07600	COG3920	Histidine kinase
AEB_RS07605	COG2967	ApaG domain
AEB_RS07615	COG0210	DNA helicase
AEB_RS07620	COG0742	ribosomal rna small subunit methyltransferase
AEB_RS07625	COG1187	pseudouridine synthase activity
AEB_RS07635	COG0285	dihydrofolate synthase activity
AEB_RS07640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AEB_RS07645	COG0159	tryptophan synthase activity
AEB_RS07650	COG2852	Protein conserved in bacteria
AEB_RS07655	COG0133	tryptophan synthase activity
AEB_RS07660	COG0135	phosphoribosylanthranilate isomerase activity
AEB_RS07670	COG0284	orotidine-5'-phosphate decarboxylase activity
AEB_RS07680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AEB_RS07700	COG2003	Belongs to the UPF0758 family
AEB_RS07725	COG0356	it plays a direct role in the translocation of protons across the membrane
AEB_RS07730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEB_RS07735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_RS07740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_RS07750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_RS07765	COG0539	negative regulation of cytoplasmic translation
AEB_RS07770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AEB_RS07775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AEB_RS07790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEB_RS07795	COG0228	four-way junction DNA binding
AEB_RS07800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEB_RS07810	COG0336	Belongs to the RNA methyltransferase TrmD family
AEB_RS07815	COG0335	large ribosomal subunit rRNA binding
AEB_RS07825	COG0531	amino acid
AEB_RS07830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEB_RS07855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AEB_RS07860	COG0359	binds to the 23S rRNA
AEB_RS07865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEB_RS07870	COG0360	Binds together with S18 to 16S ribosomal RNA
AEB_RS07880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEB_RS07915	COG1472	Belongs to the glycosyl hydrolase 3 family
AEB_RS07925	COG5001	Diguanylate cyclase
AEB_RS07925	COG3300	MHYT domain
AEB_RS07930	COG5001	Diguanylate cyclase
AEB_RS07930	COG3300	MHYT domain
AEB_RS07935	COG0481	GTPase activity
AEB_RS07950	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEB_RS07975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEB_RS07985	COG1742	UPF0060 membrane protein
AEB_RS07995	COG2264	protein methyltransferase activity
AEB_RS08025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEB_RS08050	COG2321	neutral zinc metallopeptidase
AEB_RS08055	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS08065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEB_RS08075	COG1051	belongs to the nudix hydrolase family
AEB_RS08080	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEB_RS08080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEB_RS08085	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEB_RS08090	COG0583	DNA-binding transcription factor activity
AEB_RS08100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEB_RS08105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEB_RS08110	COG0049	tRNA binding
AEB_RS08115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEB_RS08120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AEB_RS08125	COG0051	transcription antitermination factor activity, RNA binding
AEB_RS08130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEB_RS08135	COG0088	Forms part of the polypeptide exit tunnel
AEB_RS08140	COG0089	rRNA binding
AEB_RS08145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEB_RS08150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEB_RS08155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AEB_RS08160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEB_RS08165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEB_RS08170	COG0255	Belongs to the universal ribosomal protein uL29 family
AEB_RS08175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEB_RS08180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AEB_RS08185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEB_RS08190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEB_RS08195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEB_RS08200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEB_RS08205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEB_RS08210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AEB_RS08215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEB_RS08220	COG1841	ribosomal large subunit assembly
AEB_RS08225	COG0200	Binds to the 23S rRNA
AEB_RS08230	COG0201	protein transport
AEB_RS08235	COG0563	adenylate kinase activity
AEB_RS08240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEB_RS08245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEB_RS08250	COG0202	RNA polymerase activity
AEB_RS08255	COG0203	ribosomal protein L17
AEB_RS08260	COG1505	serine-type exopeptidase activity
AEB_RS08275	COG2860	membrane
AEB_RS08290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEB_RS08295	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_RS08300	COG0567	Dehydrogenase, E1 component
AEB_RS08305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AEB_RS08315	COG0039	L-malate dehydrogenase activity
AEB_RS08320	COG5001	Diguanylate cyclase
AEB_RS08320	COG3300	MHYT domain
AEB_RS08335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AEB_RS08350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEB_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS08425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEB_RS08430	COG0137	argininosuccinate synthase activity
AEB_RS08435	COG0534	Mate efflux family protein
AEB_RS08440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_RS08445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEB_RS08450	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AEB_RS08485	COG3724	N-succinylarginine dihydrolase activity
AEB_RS08510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEB_RS08515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AEB_RS08520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEB_RS08530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEB_RS08540	COG0105	UTP biosynthetic process
AEB_RS08550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEB_RS08555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AEB_RS08570	COG1045	serine acetyltransferase
AEB_RS08580	COG0546	phosphoglycolate phosphatase activity
AEB_RS08585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEB_RS08590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEB_RS08600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_RS08605	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEB_RS08610	COG2080	2 iron, 2 sulfur cluster binding
AEB_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS08620	COG3387	PFAM Glycoside hydrolase 15-related
AEB_RS08625	COG5001	Diguanylate cyclase
AEB_RS08630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEB_RS08635	COG1733	regulation of RNA biosynthetic process
AEB_RS08645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AEB_RS08680	COG0741	lytic transglycosylase activity
AEB_RS08685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEB_RS08690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AEB_RS08715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AEB_RS08725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEB_RS08735	COG3153	acetyltransferase
AEB_RS08735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEB_RS08740	COG0538	isocitrate dehydrogenase activity
AEB_RS08790	COG0513	Belongs to the DEAD box helicase family
AEB_RS08800	COG0415	Belongs to the DNA photolyase family
AEB_RS08805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS08820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AEB_RS08900	COG2059	Chromate
AEB_RS08940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AEB_RS08970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEB_RS08990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEB_RS09000	COG0126	phosphoglycerate kinase activity
AEB_RS09005	COG3588	fructose-bisphosphate aldolase
AEB_RS09015	COG0352	thiamine-phosphate diphosphorylase activity
AEB_RS09025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AEB_RS09030	COG0483	inositol monophosphate 1-phosphatase activity
AEB_RS09040	COG0471	metal ion transport
AEB_RS09040	COG3273	potassium ion transport
AEB_RS09045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_RS09050	COG0784	Response regulator, receiver
AEB_RS09050	COG2205	protein histidine kinase activity
AEB_RS09050	COG2198	Histidine kinase
AEB_RS09055	COG2204	response regulator
AEB_RS09070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AEB_RS09075	COG0531	amino acid
AEB_RS09120	COG0745	RESPONSE REGULATOR receiver
AEB_RS09125	COG0704	Plays a role in the regulation of phosphate uptake
AEB_RS09130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AEB_RS09140	COG0573	inorganic phosphate transmembrane transporter activity
AEB_RS09150	COG3746	phosphate-selective porin O and P
AEB_RS09155	COG5002	protein histidine kinase activity
AEB_RS09165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AEB_RS09190	COG0438	transferase activity, transferring glycosyl groups
AEB_RS09195	COG0438	transferase activity, transferring glycosyl groups
AEB_RS09205	COG3206	protein involved in exopolysaccharide biosynthesis
AEB_RS09205	COG0489	protein tyrosine kinase activity
AEB_RS09210	COG2197	response regulator
AEB_RS09215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEB_RS09220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEB_RS09240	COG2755	lipolytic protein G-D-S-L family
AEB_RS09240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEB_RS09250	COG1086	Polysaccharide biosynthesis protein
AEB_RS09255	COG0438	transferase activity, transferring glycosyl groups
AEB_RS09260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEB_RS09260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_RS09265	COG2197	response regulator
AEB_RS09270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_RS09285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEB_RS09305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEB_RS09310	COG2353	YceI-like domain
AEB_RS09315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AEB_RS09325	COG0028	Belongs to the TPP enzyme family
AEB_RS09330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AEB_RS09335	COG0560	Phosphoserine phosphatase
AEB_RS09340	COG2311	Membrane
AEB_RS09345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEB_RS09350	COG1722	exodeoxyribonuclease VII activity
AEB_RS09355	COG0142	geranyltranstransferase activity
AEB_RS09360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEB_RS09370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AEB_RS09375	COG1131	(ABC) transporter
AEB_RS09380	COG0842	Transport permease protein
AEB_RS09390	COG0343	queuine tRNA-ribosyltransferase activity
AEB_RS09395	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS09400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AEB_RS09410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEB_RS09420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AEB_RS09425	COG0698	ribose 5-phosphate isomerase
AEB_RS09435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEB_RS09440	COG0358	DNA primase activity
AEB_RS09450	COG0505	Belongs to the CarA family
AEB_RS09465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEB_RS09495	COG0148	phosphopyruvate hydratase activity
AEB_RS09500	COG0667	Aldo Keto reductase
AEB_RS09505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_RS09515	COG1304	FMN binding
AEB_RS09535	COG0437	4 iron, 4 sulfur cluster binding
AEB_RS09570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AEB_RS09590	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AEB_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS09625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEB_RS09655	COG2032	superoxide dismutase activity
AEB_RS09660	COG1335	isochorismatase
AEB_RS09665	COG2943	transferase activity, transferring hexosyl groups
AEB_RS09670	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AEB_RS09685	COG1295	ribonuclease BN
AEB_RS09705	COG4771	TonB-dependent receptor
AEB_RS09715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_RS09740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_RS09765	COG1260	myo-inositol-1-phosphate synthase
AEB_RS09770	COG1063	alcohol dehydrogenase
AEB_RS09775	COG0673	inositol 2-dehydrogenase activity
AEB_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS09795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_RS09805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AEB_RS09825	COG1877	trehalose-phosphatase activity
AEB_RS09830	COG3387	PFAM Glycoside hydrolase 15-related
AEB_RS09835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AEB_RS09870	COG3706	GGDEF domain
AEB_RS09875	COG0156	8-amino-7-oxononanoate synthase activity
AEB_RS09880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEB_RS09885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AEB_RS09890	COG0758	DNA mediated transformation
AEB_RS09895	COG1754	DNA topoisomerase type I activity
AEB_RS09895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEB_RS09905	COG2814	Major facilitator Superfamily
AEB_RS09910	COG2885	chlorophyll binding
AEB_RS09915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AEB_RS09920	COG0571	ribonuclease III activity
AEB_RS09925	COG0681	Belongs to the peptidase S26 family
AEB_RS09930	COG0166	Belongs to the GPI family
AEB_RS09935	COG0513	Belongs to the DEAD box helicase family
AEB_RS09945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEB_RS09965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AEB_RS09970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AEB_RS09980	COG4974	Belongs to the 'phage' integrase family
AEB_RS09985	COG0825	malonyl-CoA metabolic process
AEB_RS10005	COG0494	nUDIX hydrolase
AEB_RS10015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_RS10020	COG0302	gtp cyclohydrolase
AEB_RS10030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AEB_RS10030	COG0678	peroxiredoxin activity
AEB_RS10035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEB_RS10040	COG2205	protein histidine kinase activity
AEB_RS10045	COG0802	atpase or kinase
AEB_RS10050	COG3178	'Phosphotransferase
AEB_RS10055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEB_RS10065	COG1074	ATP-dependent DNA helicase activity
AEB_RS10075	COG0483	inositol monophosphate 1-phosphatase activity
AEB_RS10080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AEB_RS10090	COG0653	protein targeting
AEB_RS10100	COG2271	Major facilitator Superfamily
AEB_RS10140	COG3750	Belongs to the UPF0335 family
AEB_RS10365	COG0582	viral genome integration into host DNA
AEB_RS10390	COG0582	viral genome integration into host DNA
AEB_RS10400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AEB_RS10405	COG5001	Diguanylate cyclase
AEB_RS10410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEB_RS10420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEB_RS10425	COG0488	(ABC) transporter
AEB_RS10435	COG1136	(ABC) transporter
AEB_RS10450	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AEB_RS10450	COG2885	chlorophyll binding
AEB_RS10460	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEB_RS10480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AEB_RS10490	COG0129	dihydroxy-acid dehydratase activity
AEB_RS10500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AEB_RS10500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEB_RS10505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEB_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
AEB_RS10550	COG0489	protein tyrosine kinase activity
AEB_RS10560	COG3267	Type II secretory pathway component ExeA
AEB_RS10560	COG3409	Peptidoglycan-binding domain 1 protein
AEB_RS10590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AEB_RS10610	COG0297	glycogen (starch) synthase activity
AEB_RS10620	COG2244	polysaccharide biosynthetic process
AEB_RS10630	COG1530	ribonuclease E activity
AEB_RS10640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEB_RS10645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEB_RS10675	COG0183	Belongs to the thiolase family
AEB_RS10680	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_RS10685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_RS10690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_RS10695	COG0649	NAD binding
AEB_RS10705	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AEB_RS10710	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEB_RS10720	COG1034	ATP synthesis coupled electron transport
AEB_RS10725	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEB_RS10735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEB_RS10745	COG0713	ATP synthesis coupled electron transport
AEB_RS10760	COG1007	ATP synthesis coupled electron transport
AEB_RS10770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEB_RS10810	COG2205	protein histidine kinase activity
AEB_RS10820	COG0372	Belongs to the citrate synthase family
AEB_RS10825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEB_RS10830	COG0658	competence protein
AEB_RS10830	COG2333	competence protein COMEC
AEB_RS10835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEB_RS10840	COG0303	'Molybdopterin
AEB_RS10845	COG0315	cyclic pyranopterin monophosphate synthase activity
AEB_RS10850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEB_RS10860	COG0134	indole-3-glycerol-phosphate synthase activity
AEB_RS10865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AEB_RS10875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEB_RS10885	COG0149	triose-phosphate isomerase activity
AEB_RS10895	COG0504	CTP synthase activity
AEB_RS10900	COG0071	Belongs to the small heat shock protein (HSP20) family
AEB_RS10910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEB_RS10935	COG5001	Diguanylate cyclase
AEB_RS10935	COG3300	MHYT domain
AEB_RS10950	COG4771	TonB-dependent receptor
AEB_RS10975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEB_RS10980	COG0022	dehydrogenase e1 component
AEB_RS10980	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_RS11010	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AEB_RS11020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEB_RS11030	COG0012	GTP binding
AEB_RS11040	COG0193	aminoacyl-tRNA hydrolase activity
AEB_RS11045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AEB_RS11060	COG0752	glycyl-tRNA synthetase alpha subunit
AEB_RS11065	COG0751	glycine-tRNA ligase activity
AEB_RS11070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_RS11070	COG0574	Belongs to the PEP-utilizing enzyme family
AEB_RS11080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AEB_RS11085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEB_RS11090	COG1960	acyl-CoA dehydrogenase activity
AEB_RS11120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AEB_RS11130	COG3876	Protein conserved in bacteria
AEB_RS11140	COG0840	transmembrane signaling receptor activity
AEB_RS11150	COG0187	DNA topoisomerase II activity
AEB_RS11160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AEB_RS11165	COG0792	nuclease activity
AEB_RS11170	COG0189	ligase activity
AEB_RS11175	COG0586	Pfam SNARE associated Golgi protein
AEB_RS11180	COG4974	Belongs to the 'phage' integrase family
AEB_RS11185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEB_RS11190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AEB_RS11195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AEB_RS11200	COG1420	regulation of RNA biosynthetic process
AEB_RS11205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEB_RS11225	COG0443	Heat shock 70 kDa protein
AEB_RS11230	COG0484	heat shock protein binding
AEB_RS11250	COG0477	Major facilitator Superfamily
AEB_RS11255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEB_RS11265	COG0442	prolyl-tRNA aminoacylation
AEB_RS11270	COG2234	aminopeptidase activity
AEB_RS11275	COG0557	exoribonuclease II activity
AEB_RS11285	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEB_RS11295	COG1607	acyl-coa hydrolase
AEB_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEB_RS11320	COG2951	lytic endotransglycosylase activity
AEB_RS11325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AEB_RS11330	COG1686	Belongs to the peptidase S11 family
AEB_RS11335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AEB_RS11350	COG0084	hydrolase, TatD family'
AEB_RS11355	COG0321	lipoyl(octanoyl) transferase activity
AEB_RS11355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AEB_RS11365	COG5487	UPF0391 membrane protein
AEB_RS11370	COG3956	TIGRFAM MazG family protein
AEB_RS11375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEB_RS11380	COG1923	regulation of RNA biosynthetic process
AEB_RS11385	COG2204	response regulator
AEB_RS11390	COG5000	phosphorelay sensor kinase activity
AEB_RS11395	COG2204	response regulator
AEB_RS11400	COG3852	Histidine kinase
AEB_RS11410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AEB_RS11410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEB_RS11420	COG1546	Belongs to the CinA family
AEB_RS11425	COG2867	negative regulation of translational initiation
AEB_RS11430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AEB_RS11450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AEB_RS11450	COG0678	peroxiredoxin activity
AEB_RS11460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AEB_RS11485	COG0772	Belongs to the SEDS family
AEB_RS11555	COG4771	TonB-dependent receptor
AEB_RS11585	COG1872	DUF167
AEB_RS11590	COG2824	Alkylphosphonate utilization operon protein PhnA
AEB_RS11640	COG4974	Belongs to the 'phage' integrase family
AEB_RS11780	COG4957	zinc ion binding
AEB_RS11830	COG4206	TonB-dependent receptor
AEB_RS11835	COG0823	Involved in the tonB-independent uptake of proteins
AEB_RS11835	COG1506	peptidase
AEB_RS12015	COG0776	regulation of translation
AEB_RS12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEB_RS12075	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS12080	COG1024	Enoyl-CoA hydratase
AEB_RS12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_RS12095	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS12095	COG2030	dehydratase
AEB_RS12100	COG1024	Enoyl-CoA hydratase
AEB_RS12105	COG2050	protein possibly involved in aromatic compounds catabolism
AEB_RS12110	COG0183	Belongs to the thiolase family
AEB_RS12115	COG3396	Phenylacetate-CoA oxygenase
AEB_RS12120	COG3460	Phenylacetate-CoA oxygenase
AEB_RS12125	COG3396	Phenylacetate-CoA oxygenase
AEB_RS12130	COG2151	metal-sulfur cluster biosynthetic enzyme
AEB_RS12135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AEB_RS12155	COG0371	Dehydrogenase
AEB_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS12175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEB_RS12180	COG0183	Belongs to the thiolase family
AEB_RS12215	COG3485	protocatechuate 3,4-dioxygenase
AEB_RS12240	COG0582	viral genome integration into host DNA
AEB_RS12255	COG2963	transposase activity
AEB_RS12260	COG3436	PFAM IS66 Orf2 family protein
AEB_RS12265	COG4372	Transposase
AEB_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS12295	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEB_RS12310	COG1960	acyl-CoA dehydrogenase activity
AEB_RS12335	COG1309	transcriptional regulator
AEB_RS12340	COG1414	Transcriptional regulator
AEB_RS12370	COG0431	NADPH-dependent FMN reductase
AEB_RS12380	COG3384	dioxygenase
AEB_RS12385	COG0400	carboxylic ester hydrolase activity
AEB_RS12390	COG2259	Doxx family
AEB_RS12400	COG0583	DNA-binding transcription factor activity
AEB_RS12420	COG1942	4-Oxalocrotonate Tautomerase
AEB_RS12425	COG2267	carboxylic ester hydrolase activity
AEB_RS12450	COG3713	MltA-interacting MipA family protein
AEB_RS12460	COG0582	viral genome integration into host DNA
AEB_RS12570	COG0583	DNA-binding transcription factor activity
AEB_RS12580	COG0445	tRNA wobble uridine modification
AEB_RS12595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_RS12600	COG0583	DNA-binding transcription factor activity
AEB_RS12605	COG4771	TonB-dependent receptor
AEB_RS12645	COG1228	amidohydrolase
AEB_RS12650	COG2986	histidine ammonia-lyase
AEB_RS12660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AEB_RS12665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEB_RS12685	COG1629	transport
AEB_RS12685	COG4774	siderophore transport
AEB_RS12695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AEB_RS12705	COG2205	protein histidine kinase activity
AEB_RS12710	COG2814	Major facilitator Superfamily
AEB_RS12715	COG0028	Belongs to the TPP enzyme family
AEB_RS12735	COG1414	Transcriptional regulator
AEB_RS12745	COG2222	sugar isomerase
AEB_RS12775	COG1349	DNA-binding transcription factor activity
AEB_RS12795	COG0129	dihydroxy-acid dehydratase activity
AEB_RS12800	COG4206	TonB-dependent receptor
AEB_RS12805	COG0583	DNA-binding transcription factor activity
AEB_RS12810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEB_RS12855	COG0583	DNA-binding transcription factor activity
AEB_RS12860	COG0667	Aldo Keto reductase
AEB_RS12900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEB_RS12905	COG0366	Alpha amylase catalytic
AEB_RS12915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEB_RS12925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AEB_RS12930	COG1640	4-alpha-glucanotransferase
AEB_RS12955	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEB_RS12960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AEB_RS12965	COG2205	protein histidine kinase activity
AEB_RS12970	COG0745	RESPONSE REGULATOR receiver
AEB_RS12975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_RS12985	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AEB_RS12990	COG0784	Response regulator, receiver
AEB_RS12995	COG4191	Histidine kinase
AEB_RS12995	COG0784	Response regulator, receiver
AEB_RS13110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AEB_RS13130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_RS13135	COG0450	alkyl hydroperoxide reductase
AEB_RS13145	COG1294	oxidase, subunit
AEB_RS13165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEB_RS13180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_RS13190	COG2890	protein-(glutamine-N5) methyltransferase activity
AEB_RS13225	COG1482	cell wall glycoprotein biosynthetic process
AEB_RS13240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AEB_RS13245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_RS13265	COG1620	l-lactate permease
AEB_RS13280	COG2217	Heavy metal translocating P-type atpase
AEB_RS13285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AEB_RS13290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AEB_RS13295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEB_RS13310	COG1937	Protein conserved in bacteria
AEB_RS13320	COG2217	Heavy metal translocating P-type atpase
AEB_RS13335	COG0670	Belongs to the BI1 family
AEB_RS13365	COG0148	phosphopyruvate hydratase activity
AEB_RS13370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEB_RS13370	COG0574	Belongs to the PEP-utilizing enzyme family
AEB_RS13380	COG0517	IMP dehydrogenase activity
AEB_RS13385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEB_RS13390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEB_RS13400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_RS13410	COG1595	DNA-templated transcription, initiation
AEB_RS13445	COG3920	Histidine kinase
AEB_RS13455	COG0126	phosphoglycerate kinase activity
AEB_RS13465	COG2132	Multicopper oxidase
AEB_RS13470	COG1063	alcohol dehydrogenase
AEB_RS13475	COG0672	)-iron permease
AEB_RS13505	COG5290	Psort location Cytoplasmic, score
AEB_RS13510	COG2814	Major facilitator Superfamily
AEB_RS13515	COG0657	acetylesterase activity
AEB_RS13515	COG2755	lipolytic protein G-D-S-L family
AEB_RS13525	COG0673	inositol 2-dehydrogenase activity
AEB_RS13545	COG2211	Major facilitator Superfamily
AEB_RS13555	COG4771	TonB-dependent receptor
AEB_RS13560	COG1940	carbohydrate kinase activity
AEB_RS13565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_RS13635	COG4227	nucleotidyltransferase activity
AEB_RS13680	COG5642	Protein of unknown function (DUF2384)
AEB_RS13695	COG0739	heme binding
AEB_RS13695	COG1196	nuclear chromosome segregation
AEB_RS13695	COG0741	lytic transglycosylase activity
AEB_RS13700	COG0582	viral genome integration into host DNA
AEB_RS13710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AEB_RS13715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEB_RS13720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEB_RS13725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEB_RS13730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AEB_RS13735	COG0583	DNA-binding transcription factor activity
AEB_RS13740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEB_RS13755	COG0028	Belongs to the TPP enzyme family
AEB_RS13770	COG5001	Diguanylate cyclase
AEB_RS13770	COG3300	MHYT domain
AEB_RS13775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AEB_RS13780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEB_RS13785	COG0552	protein localization to endoplasmic reticulum
AEB_RS13790	COG2917	probably involved in intracellular septation
AEB_RS13795	COG3158	transport of potassium into the cell
AEB_RS13800	COG4235	cytochrome complex assembly
AEB_RS13805	COG3088	subunit of a heme lyase
AEB_RS13810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEB_RS13815	COG1138	Cytochrome C-type biogenesis protein
AEB_RS13820	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AEB_RS13830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEB_RS13855	COG0254	rRNA binding
AEB_RS13860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEB_RS13875	COG0750	zinc metalloprotease
AEB_RS13880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AEB_RS13890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AEB_RS13895	COG0233	cytoplasmic translational termination
AEB_RS13900	COG0528	UMP kinase activity
AEB_RS13905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AEB_RS13910	COG0052	Belongs to the universal ribosomal protein uS2 family
AEB_RS13925	COG0688	phosphatidylethanolamine metabolic process
AEB_RS13930	COG5001	Diguanylate cyclase
AEB_RS13930	COG1716	ATPase activity
AEB_RS13940	COG0515	serine threonine protein kinase
AEB_RS13940	COG2815	serine threonine protein kinase
AEB_RS13950	COG0631	protein serine/threonine phosphatase activity
AEB_RS13960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEB_RS13985	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEB_RS14005	COG1643	Atp-dependent helicase
AEB_RS14010	COG0142	geranyltranstransferase activity
AEB_RS14015	COG0287	Prephenate dehydrogenase
AEB_RS14015	COG1605	Chorismate mutase
AEB_RS14045	COG0488	(ABC) transporter
AEB_RS14060	COG0438	transferase activity, transferring glycosyl groups
AEB_RS14065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEB_RS14070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEB_RS14075	COG1862	Preprotein translocase
AEB_RS14090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEB_RS14095	COG0511	ligase activity, forming carbon-carbon bonds
AEB_RS14100	COG0439	Biotin carboxylase
AEB_RS14105	COG1522	sequence-specific DNA binding
AEB_RS14110	COG2205	protein histidine kinase activity
AEB_RS14170	COG0668	transmembrane transport
AEB_RS14185	COG1199	ATP-dependent helicase activity
AEB_RS14185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEB_RS14200	COG0776	regulation of translation
AEB_RS14205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEB_RS14210	COG0416	fatty acid biosynthetic process
AEB_RS14215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AEB_RS14220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEB_RS14225	COG2827	Endonuclease containing a URI domain
AEB_RS14250	COG0215	cysteine-tRNA ligase activity
AEB_RS14260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AEB_RS14290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEB_RS14295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AEB_RS14300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AEB_RS14305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEB_RS14310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AEB_RS14350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEB_RS14390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEB_RS14410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEB_RS14415	COG2133	pyrroloquinoline quinone binding
AEB_RS14435	COG0617	tRNA 3'-terminal CCA addition
AEB_RS14445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEB_RS14450	COG0693	protein deglycase activity
AEB_RS14455	COG0633	Ferredoxin
AEB_RS14460	COG1104	cysteine desulfurase activity
AEB_RS14470	COG2945	thiolester hydrolase activity
AEB_RS14495	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AEB_RS14500	COG0745	RESPONSE REGULATOR receiver
AEB_RS14505	COG0642	Histidine kinase
AEB_RS14515	COG1660	Displays ATPase and GTPase activities
AEB_RS14520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AEB_RS14520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AEB_RS14530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEB_RS14540	COG1322	Protein conserved in bacteria
AEB_RS14545	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AEB_RS14560	COG0242	peptide deformylase activity
AEB_RS14565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEB_RS14570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEB_RS14580	COG0101	tRNA pseudouridine synthase activity
AEB_RS14585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEB_RS14595	COG1733	regulation of RNA biosynthetic process
AEB_RS14610	COG5507	3-demethylubiquinone-9 3-methyltransferase
AEB_RS14650	COG1741	Belongs to the pirin family
AEB_RS14665	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AEB_RS14670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AEB_RS14675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEB_RS14685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEB_RS14690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEB_RS14710	COG0322	excinuclease ABC activity
AEB_RS14720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEB_RS14725	COG0424	maF-like protein
AEB_RS14735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AEB_RS14745	COG3263	regulation of cellular component size
AEB_RS14785	COG0457	Tetratricopeptide repeat
AEB_RS14785	COG3710	Transcriptional regulator
AEB_RS14795	COG0583	DNA-binding transcription factor activity
AEB_RS14810	COG1172	Belongs to the binding-protein-dependent transport system permease family
AEB_RS14830	COG2814	Major facilitator Superfamily
AEB_RS14835	COG0385	Bile acid
AEB_RS14845	COG2252	PERMEase
AEB_RS14850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AEB_RS14865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AEB_RS14910	COG0402	S-adenosylhomocysteine deaminase activity
AEB_RS14930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_RS14935	COG0346	lactoylglutathione lyase activity
AEB_RS14945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEB_RS14950	COG0583	DNA-binding transcription factor activity
AEB_RS15030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEB_RS15045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEB_RS15050	COG3047	cAMP biosynthetic process
AEB_RS15055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEB_RS15075	COG2271	Major facilitator Superfamily
AEB_RS15080	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEB_RS15085	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AEB_RS15090	COG1733	regulation of RNA biosynthetic process
AEB_RS15100	COG4206	TonB-dependent receptor
AEB_RS15110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEB_RS15115	COG0612	Peptidase, M16
AEB_RS15125	COG2132	Multicopper oxidase
AEB_RS15130	COG1937	Protein conserved in bacteria
AEB_RS15135	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEB_RS15140	COG0047	phosphoribosylformylglycinamidine synthase activity
AEB_RS15145	COG1970	mechanosensitive ion channel activity
AEB_RS15180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEB_RS15185	COG0572	uridine kinase
AEB_RS15190	COG4993	Dehydrogenase
AEB_RS15200	COG2010	Cytochrome c
AEB_RS15250	COG4993	Dehydrogenase
AEB_RS15285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AEB_RS15290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AEB_RS15295	COG2080	2 iron, 2 sulfur cluster binding
AEB_RS15315	COG4566	intracellular signal transduction
AEB_RS15335	COG4566	intracellular signal transduction
AEB_RS15340	COG4191	Histidine kinase
AEB_RS15345	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS15385	COG1132	(ABC) transporter
AEB_RS15400	COG0457	Tetratricopeptide repeat
AEB_RS15440	COG0457	Tetratricopeptide repeat
AEB_RS15465	COG1464	Belongs to the NlpA lipoprotein family
AEB_RS15475	COG1116	anion transmembrane transporter activity
AEB_RS15480	COG0864	Transcriptional regulator
AEB_RS15495	COG0439	Biotin carboxylase
AEB_RS15520	COG4946	Tricorn protease homolog
AEB_RS15520	COG0793	Belongs to the peptidase S41A family
AEB_RS15525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEB_RS15535	COG3243	poly(R)-hydroxyalkanoic acid synthase
AEB_RS15560	COG5001	Diguanylate cyclase
AEB_RS15565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEB_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS15580	COG4206	TonB-dependent receptor
AEB_RS15595	COG0489	protein tyrosine kinase activity
AEB_RS15635	COG0438	transferase activity, transferring glycosyl groups
AEB_RS15655	COG1215	transferase activity, transferring glycosyl groups
AEB_RS15685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEB_RS15695	COG2311	Membrane
AEB_RS15705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AEB_RS15710	COG1012	belongs to the aldehyde dehydrogenase family
AEB_RS15715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AEB_RS15725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AEB_RS15730	COG1113	amino acid transport
AEB_RS15740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AEB_RS15745	COG0583	DNA-binding transcription factor activity
AEB_RS15750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AEB_RS15760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEB_RS15765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEB_RS15780	COG4771	TonB-dependent receptor
AEB_RS15785	COG1506	peptidase
AEB_RS15785	COG0823	Involved in the tonB-independent uptake of proteins
AEB_RS15790	COG3210	domain, Protein
AEB_RS15810	COG0708	Exodeoxyribonuclease III
AEB_RS15815	COG0688	phosphatidylethanolamine metabolic process
AEB_RS15860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AEB_RS15865	COG0732	type I restriction modification DNA specificity domain
AEB_RS15880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEB_RS15905	COG4227	nucleotidyltransferase activity
AEB_RS15925	COG0842	Transport permease protein
AEB_RS15935	COG1506	peptidase
AEB_RS15960	COG1185	polyribonucleotide nucleotidyltransferase activity
AEB_RS15965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEB_RS15970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AEB_RS15980	COG1994	Peptidase M50
AEB_RS15985	COG1435	thymidine kinase activity
AEB_RS15990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AEB_RS16000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEB_RS16015	COG0779	Required for maturation of 30S ribosomal subunits
AEB_RS16020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AEB_RS16030	COG1842	Phage shock protein A
AEB_RS16070	COG2166	iron-sulfur cluster assembly
AEB_RS16085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEB_RS16100	COG0066	3-isopropylmalate dehydratase activity
AEB_RS16110	COG0271	Belongs to the BolA IbaG family
AEB_RS16115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AEB_RS16120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AEB_RS16150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AEB_RS16155	COG2755	lipolytic protein G-D-S-L family
AEB_RS16160	COG4181	ATPase activity
AEB_RS16170	COG0297	glycogen (starch) synthase activity
AEB_RS16175	COG1695	Transcriptional regulator
AEB_RS16180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEB_RS16195	COG1959	2 iron, 2 sulfur cluster binding
AEB_RS16210	COG0730	response to heat
AEB_RS16225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AEB_RS16235	COG2897	thiosulfate sulfurtransferase activity
AEB_RS16240	COG0626	cystathionine gamma-synthase activity
AEB_RS16245	COG0668	transmembrane transport
AEB_RS16250	COG1648	precorrin-2 dehydrogenase activity
AEB_RS16250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AEB_RS16260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AEB_RS16270	COG0175	sulfate reduction
AEB_RS16275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEB_RS16280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AEB_RS16285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEB_RS16300	COG0670	Belongs to the BI1 family
AEB_RS16305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AEB_RS16325	COG0849	cell division
AEB_RS16330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEB_RS16335	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEB_RS16340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEB_RS16345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEB_RS16350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEB_RS16360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEB_RS16365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AEB_RS16370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEB_RS16375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AEB_RS16390	COG0275	rRNA processing
AEB_RS16395	COG2001	Belongs to the MraZ family
AEB_RS16410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEB_RS16420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AEB_RS16435	COG2154	pterin-4-alpha-carbinolamine dehydratase
AEB_RS16440	COG4133	protoheme IX ABC transporter activity
AEB_RS16445	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEB_RS16450	COG0024	Methionine aminopeptidase
AEB_RS16460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AEB_RS16480	COG0174	glutamine synthetase
AEB_RS16495	COG0729	surface antigen
AEB_RS16500	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AEB_RS16505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEB_RS16510	COG2084	Dehydrogenase
AEB_RS16515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AEB_RS16520	COG0805	protein transport
AEB_RS16525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_RS16530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEB_RS16535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEB_RS16540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AEB_RS16545	COG1472	Belongs to the glycosyl hydrolase 3 family
AEB_RS16560	COG0018	arginyl-trna synthetase
AEB_RS16570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AEB_RS16575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AEB_RS16580	COG0328	RNA-DNA hybrid ribonuclease activity
AEB_RS16605	COG4964	Belongs to the GSP D family
AEB_RS16630	COG1846	Transcriptional regulator
AEB_RS16635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEB_RS16645	COG4771	TonB-dependent receptor
AEB_RS16670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AEB_RS16675	COG0688	phosphatidylethanolamine metabolic process
AEB_RS16685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AEB_RS16700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEB_RS16710	COG0154	amidase activity
AEB_RS16715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEB_RS16725	COG0545	Peptidyl-prolyl cis-trans isomerase
AEB_RS16730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AEB_RS16735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEB_RS16750	COG0546	phosphoglycolate phosphatase activity
AEB_RS16780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEB_RS16785	COG0525	valine-tRNA ligase activity
AEB_RS16795	COG0534	Mate efflux family protein
AEB_RS16800	COG0784	Response regulator, receiver
AEB_RS16815	COG0730	response to heat
AEB_RS16845	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEB_RS16855	COG0740	serine-type endopeptidase activity
AEB_RS16860	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEB_RS16885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEB_RS16890	COG0564	pseudouridine synthase activity
AEB_RS16905	COG3023	N-Acetylmuramoyl-L-alanine amidase
AEB_RS16915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AEB_RS16935	COG1160	GTP binding
AEB_RS16940	COG2193	ferroxidase activity
AEB_RS16970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEB_RS16975	COG0540	Belongs to the ATCase OTCase family
AEB_RS16980	COG0616	signal peptide processing
AEB_RS16995	COG4771	TonB-dependent receptor
AEB_RS17000	COG0457	Tetratricopeptide repeat
AEB_RS17005	COG0488	(ABC) transporter
AEB_RS17020	COG1846	Transcriptional regulator
AEB_RS17030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AEB_RS17035	COG1917	Cupin 2, conserved barrel domain protein
AEB_RS17040	COG5285	phytanoyl-CoA dioxygenase
AEB_RS17045	COG0527	aspartate kinase activity
AEB_RS17050	COG0477	Major facilitator Superfamily
AEB_RS17055	COG0477	Major facilitator Superfamily
AEB_RS17060	COG0583	DNA-binding transcription factor activity
AEB_RS17070	COG3119	arylsulfatase activity
AEB_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
AEB_RS17100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEB_RS17110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEB_RS17115	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEB_RS17140	COG4771	TonB-dependent receptor
AEB_RS17155	COG1472	Belongs to the glycosyl hydrolase 3 family
AEB_RS17170	COG3119	arylsulfatase activity
AEB_RS17175	COG3119	arylsulfatase activity
AEB_RS17180	COG3119	arylsulfatase activity
AEB_RS17185	COG3119	arylsulfatase activity
AEB_RS17190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEB_RS17195	COG1609	Transcriptional regulator
AEB_RS17200	COG3119	arylsulfatase activity
AEB_RS17220	COG0583	DNA-binding transcription factor activity
AEB_RS17225	COG0667	Aldo Keto reductase
AEB_RS17230	COG2814	Major facilitator Superfamily
AEB_RS17265	COG1393	Belongs to the ArsC family
AEB_RS17270	COG0798	PFAM Bile acid sodium symporter
AEB_RS17300	COG0408	coproporphyrinogen oxidase activity
AEB_RS17310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEB_RS17325	COG0471	metal ion transport
AEB_RS17335	COG0484	heat shock protein binding
AEB_RS17345	COG2885	chlorophyll binding
AEB_RS17350	COG0823	Involved in the tonB-independent uptake of proteins
AEB_RS17370	COG0824	Thioesterase
AEB_RS17380	COG0140	phosphoribosyl-ATP diphosphatase activity
AEB_RS17385	COG0107	imidazoleglycerol-phosphate synthase activity
AEB_RS17395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEB_RS17400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AEB_RS17405	COG0131	Imidazoleglycerol-phosphate dehydratase
AEB_RS17420	COG0194	GDP metabolic process
AEB_RS17425	COG2171	N-acyltransferase activity
AEB_RS17460	COG3384	dioxygenase
AEB_RS17520	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AEB_RS17575	COG2814	Major facilitator Superfamily
AEB_RS17615	COG1376	ErfK ybiS ycfS ynhG family protein
AEB_RS17620	COG0477	Major facilitator Superfamily
AEB_RS17625	COG2207	Transcriptional regulator
AEB_RS17630	COG4221	oxidoreductase activity
AEB_RS17635	COG1846	Transcriptional regulator
AEB_RS17645	COG1566	PFAM secretion protein HlyD family protein
AEB_RS17650	COG2814	Major facilitator Superfamily
AEB_RS17695	COG4149	molybdate abc transporter
AEB_RS17700	COG0725	ABC transporter, periplasmic molybdate-binding protein
AEB_RS17705	COG3920	Histidine kinase
AEB_RS17730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEB_RS17735	COG1823	symporter activity
AEB_RS17740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEB_RS17750	COG0351	phosphomethylpyrimidine kinase
AEB_RS17750	COG0352	thiamine-phosphate diphosphorylase activity
AEB_RS17750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AEB_RS17830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AEB_RS17840	COG0077	Prephenate dehydratase
AEB_RS17840	COG1605	Chorismate mutase
AEB_RS17855	COG0714	Associated with various cellular activities
AEB_RS17875	COG1446	asparaginase
AEB_RS17885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEB_RS17885	COG0475	glutathione-regulated potassium exporter activity
AEB_RS17890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AEB_RS17915	COG2989	Protein conserved in bacteria
AEB_RS17925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AEB_RS17935	COG2255	four-way junction helicase activity
AEB_RS17945	COG0632	four-way junction helicase activity
AEB_RS17950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEB_RS17955	COG0450	alkyl hydroperoxide reductase
AEB_RS17960	COG3634	alkyl hydroperoxide reductase activity
AEB_RS17965	COG0339	signal peptide processing
AEB_RS17980	COG4395	Tim44
AEB_RS17985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AEB_RS17990	COG0728	peptidoglycan biosynthetic process
AEB_RS17995	COG0180	Tryptophanyl-tRNA synthetase
AEB_RS18005	COG0756	dUTP diphosphatase activity
AEB_RS18010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEB_RS18020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEB_RS18025	COG2226	methyltransferase
AEB_RS18035	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AEB_RS18040	COG0268	Binds directly to 16S ribosomal RNA