locus-tag	class	description
MIT1002_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIT1002_RS00050	COG2818	Glycosylase
MIT1002_RS00060	COG3078	GTPase activator activity
MIT1002_RS00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIT1002_RS00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIT1002_RS00085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MIT1002_RS00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIT1002_RS00095	COG0569	domain protein
MIT1002_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIT1002_RS00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIT1002_RS00120	COG0758	DNA mediated transformation
MIT1002_RS00135	COG0009	L-threonylcarbamoyladenylate synthase
MIT1002_RS00140	COG0408	coproporphyrinogen oxidase activity
MIT1002_RS00145	COG3047	cAMP biosynthetic process
MIT1002_RS00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MIT1002_RS00235	COG2234	aminopeptidase activity
MIT1002_RS00245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIT1002_RS00270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_RS00300	COG3642	lipopolysaccharide core region biosynthetic process
MIT1002_RS00330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_RS00345	COG3161	chorismate lyase activity
MIT1002_RS00350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MIT1002_RS00360	COG0210	DNA helicase
MIT1002_RS00395	COG0604	alcohol dehydrogenase
MIT1002_RS00395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MIT1002_RS00395	COG3321	synthase
MIT1002_RS00395	COG4221	oxidoreductase activity
MIT1002_RS00400	COG4221	oxidoreductase activity
MIT1002_RS00405	COG0583	DNA-binding transcription factor activity
MIT1002_RS00425	COG3321	synthase
MIT1002_RS00425	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS00425	COG0604	alcohol dehydrogenase
MIT1002_RS00435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_RS00440	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS00445	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS00490	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS00495	COG3829	transcription factor binding
MIT1002_RS00505	COG1454	alcohol dehydrogenase
MIT1002_RS00655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS00660	COG0842	Transport permease protein
MIT1002_RS00660	COG1129	ABC transporter
MIT1002_RS00665	COG0842	Transport permease protein
MIT1002_RS00690	COG0583	DNA-binding transcription factor activity
MIT1002_RS00700	COG3106	COG3106 Predicted ATPase
MIT1002_RS00715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIT1002_RS00730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MIT1002_RS00735	COG0352	thiamine-phosphate diphosphorylase activity
MIT1002_RS00745	COG3071	HemY protein
MIT1002_RS00750	COG2959	enzyme of heme biosynthesis
MIT1002_RS00760	COG0181	hydroxymethylbilane synthase activity
MIT1002_RS00775	COG0194	GDP metabolic process
MIT1002_RS00785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIT1002_RS00795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_RS00800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIT1002_RS00810	COG0678	peroxiredoxin activity
MIT1002_RS00825	COG1178	ABC-type Fe3 transport system permease component
MIT1002_RS00830	COG3842	ATPase activity
MIT1002_RS00835	COG2081	HI0933 family
MIT1002_RS00840	COG3047	cAMP biosynthetic process
MIT1002_RS00855	COG2200	EAL domain
MIT1002_RS00860	COG5001	Diguanylate cyclase
MIT1002_RS00890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS00905	COG0427	acetyl-CoA hydrolase
MIT1002_RS00910	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIT1002_RS00925	COG0840	transmembrane signaling receptor activity
MIT1002_RS00935	COG3064	Membrane
MIT1002_RS00945	COG5002	protein histidine kinase activity
MIT1002_RS00945	COG5001	Diguanylate cyclase
MIT1002_RS00960	COG0514	ATP-dependent DNA helicase (RecQ)
MIT1002_RS00965	COG2050	protein possibly involved in aromatic compounds catabolism
MIT1002_RS00970	COG2239	Acts as a magnesium transporter
MIT1002_RS00975	COG2962	Rard protein
MIT1002_RS00980	COG3706	GGDEF domain
MIT1002_RS00985	COG0210	DNA helicase
MIT1002_RS00995	COG3706	GGDEF domain
MIT1002_RS01000	COG1011	Hydrolase
MIT1002_RS01005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MIT1002_RS01015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIT1002_RS01020	COG0019	diaminopimelate decarboxylase activity
MIT1002_RS01055	COG0163	prenyltransferase activity
MIT1002_RS01060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIT1002_RS01070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIT1002_RS01105	COG1077	Cell shape determining protein MreB Mrl
MIT1002_RS01115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIT1002_RS01120	COG2814	Major facilitator Superfamily
MIT1002_RS01125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIT1002_RS01155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIT1002_RS01165	COG0629	single-stranded DNA binding
MIT1002_RS01185	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_RS01200	COG1349	DNA-binding transcription factor activity
MIT1002_RS01245	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_RS01245	COG3267	Type II secretory pathway component ExeA
MIT1002_RS01255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_RS01260	COG1459	type II secretion system
MIT1002_RS01270	COG2165	general secretion pathway protein
MIT1002_RS01275	COG2165	general secretion pathway protein
MIT1002_RS01305	COG1077	Cell shape determining protein MreB Mrl
MIT1002_RS01310	COG1792	Involved in formation and maintenance of cell shape
MIT1002_RS01315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MIT1002_RS01325	COG1530	ribonuclease E activity
MIT1002_RS01335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIT1002_RS01340	COG0312	modulator of DNA gyrase
MIT1002_RS01350	COG3028	Belongs to the UPF0307 family
MIT1002_RS01355	COG0312	modulator of DNA gyrase
MIT1002_RS01370	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS01375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS01375	COG4191	Histidine kinase
MIT1002_RS01380	COG0297	glycogen (starch) synthase activity
MIT1002_RS01390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MIT1002_RS01445	COG4974	Belongs to the 'phage' integrase family
MIT1002_RS01535	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS01540	COG0643	Histidine kinase
MIT1002_RS01540	COG2198	Histidine kinase
MIT1002_RS01545	COG0835	chemotaxis
MIT1002_RS01565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MIT1002_RS01580	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS01585	COG0643	Histidine kinase
MIT1002_RS01585	COG2198	Histidine kinase
MIT1002_RS01590	COG0835	chemotaxis
MIT1002_RS01615	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MIT1002_RS01665	COG0546	phosphoglycolate phosphatase activity
MIT1002_RS01675	COG0784	Response regulator, receiver
MIT1002_RS01675	COG2205	protein histidine kinase activity
MIT1002_RS01690	COG1609	Transcriptional regulator
MIT1002_RS01695	COG0673	inositol 2-dehydrogenase activity
MIT1002_RS01705	COG2211	Major facilitator Superfamily
MIT1002_RS01730	COG1454	alcohol dehydrogenase
MIT1002_RS01785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_RS01805	COG0089	rRNA binding
MIT1002_RS01815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIT1002_RS01825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIT1002_RS01840	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIT1002_RS01850	COG1519	Transferase
MIT1002_RS01895	COG0788	formyltetrahydrofolate deformylase activity
MIT1002_RS01905	COG1643	Atp-dependent helicase
MIT1002_RS01915	COG2951	lytic endotransglycosylase activity
MIT1002_RS01920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIT1002_RS01930	COG2354	Protein conserved in bacteria
MIT1002_RS01955	COG0004	ammonium transporteR
MIT1002_RS01960	COG0405	Gamma-glutamyltransferase
MIT1002_RS01965	COG2837	iron assimilation
MIT1002_RS01980	COG0540	Belongs to the ATCase OTCase family
MIT1002_RS02005	COG0784	Response regulator, receiver
MIT1002_RS02005	COG2205	protein histidine kinase activity
MIT1002_RS02005	COG5002	protein histidine kinase activity
MIT1002_RS02020	COG5001	Diguanylate cyclase
MIT1002_RS02020	COG3300	MHYT domain
MIT1002_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS02040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MIT1002_RS02050	COG0512	Glutamine amidotransferase of anthranilate synthase
MIT1002_RS02055	COG0180	Tryptophanyl-tRNA synthetase
MIT1002_RS02060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIT1002_RS02080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MIT1002_RS02090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIT1002_RS02125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MIT1002_RS02130	COG0281	malic enzyme
MIT1002_RS02145	COG0625	glutathione transferase activity
MIT1002_RS02155	COG0753	catalase activity
MIT1002_RS02180	COG3300	MHYT domain
MIT1002_RS02180	COG5001	Diguanylate cyclase
MIT1002_RS02185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIT1002_RS02185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MIT1002_RS02195	COG0137	argininosuccinate synthase activity
MIT1002_RS02215	COG1803	Methylglyoxal synthase
MIT1002_RS02225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MIT1002_RS02240	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS02245	COG2205	protein histidine kinase activity
MIT1002_RS02250	COG2267	carboxylic ester hydrolase activity
MIT1002_RS02255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIT1002_RS02260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS02265	COG0577	efflux transmembrane transporter activity
MIT1002_RS02265	COG1136	(ABC) transporter
MIT1002_RS02280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MIT1002_RS02290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIT1002_RS02295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_RS02300	COG4942	peptidase
MIT1002_RS02305	COG2861	carbohydrate metabolic process
MIT1002_RS02315	COG0584	glycerophosphoryl diester phosphodiesterase
MIT1002_RS02330	COG1162	GTPase activity
MIT1002_RS02335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIT1002_RS02365	COG0028	Belongs to the TPP enzyme family
MIT1002_RS02385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIT1002_RS02390	COG0805	protein transport
MIT1002_RS02400	COG0084	hydrolase, TatD family'
MIT1002_RS02405	COG4251	negative regulation of phosphorylation
MIT1002_RS02405	COG3706	GGDEF domain
MIT1002_RS02405	COG2203	Gaf domain
MIT1002_RS02405	COG5001	Diguanylate cyclase
MIT1002_RS02415	COG0248	Ppx GppA phosphatase
MIT1002_RS02420	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS02425	COG3118	belongs to the thioredoxin family
MIT1002_RS02430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIT1002_RS02435	COG1473	amidohydrolase
MIT1002_RS02440	COG2205	protein histidine kinase activity
MIT1002_RS02440	COG0784	Response regulator, receiver
MIT1002_RS02445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIT1002_RS02450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIT1002_RS02455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIT1002_RS02470	COG0783	Belongs to the Dps family
MIT1002_RS02475	COG2133	pyrroloquinoline quinone binding
MIT1002_RS02480	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_RS02480	COG1506	peptidase
MIT1002_RS02480	COG4946	Tricorn protease homolog
MIT1002_RS02490	COG3118	belongs to the thioredoxin family
MIT1002_RS02505	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MIT1002_RS02515	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS02540	COG1757	Na H antiporter
MIT1002_RS02555	COG3876	Protein conserved in bacteria
MIT1002_RS02560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MIT1002_RS02580	COG0346	lactoylglutathione lyase activity
MIT1002_RS02615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIT1002_RS02625	COG2824	Alkylphosphonate utilization operon protein PhnA
MIT1002_RS02630	COG0454	-acetyltransferase
MIT1002_RS02640	COG1742	UPF0060 membrane protein
MIT1002_RS02710	COG0183	Belongs to the thiolase family
MIT1002_RS02715	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIT1002_RS02715	COG1024	Enoyl-CoA hydratase
MIT1002_RS02720	COG0739	heme binding
MIT1002_RS02720	COG0741	lytic transglycosylase activity
MIT1002_RS02720	COG1196	nuclear chromosome segregation
MIT1002_RS02725	COG0006	proline dipeptidase activity
MIT1002_RS02735	COG0142	geranyltranstransferase activity
MIT1002_RS02780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIT1002_RS02785	COG1388	LysM domain
MIT1002_RS02785	COG4942	peptidase
MIT1002_RS02790	COG1238	metal cluster binding
MIT1002_RS02800	COG0585	pseudouridine synthase activity
MIT1002_RS02805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIT1002_RS02815	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIT1002_RS02825	COG0840	transmembrane signaling receptor activity
MIT1002_RS02830	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIT1002_RS02830	COG0506	proline dehydrogenase activity
MIT1002_RS02830	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIT1002_RS02845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS02880	COG0494	nUDIX hydrolase
MIT1002_RS02885	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MIT1002_RS02890	COG0730	response to heat
MIT1002_RS02895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIT1002_RS02900	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIT1002_RS02910	COG3706	GGDEF domain
MIT1002_RS02915	COG2205	protein histidine kinase activity
MIT1002_RS02915	COG3437	response regulator, receiver
MIT1002_RS02915	COG3850	Histidine kinase
MIT1002_RS02915	COG4999	Histidine kinase
MIT1002_RS02920	COG2211	Major facilitator Superfamily
MIT1002_RS02940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIT1002_RS02955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MIT1002_RS02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIT1002_RS02980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIT1002_RS02980	COG1648	precorrin-2 dehydrogenase activity
MIT1002_RS02985	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS03005	COG1538	Outer membrane efflux protein
MIT1002_RS03010	COG0494	nUDIX hydrolase
MIT1002_RS03020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MIT1002_RS03025	COG3150	esterase
MIT1002_RS03040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIT1002_RS03060	COG1509	lysine 2,3-aminomutase activity
MIT1002_RS03065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIT1002_RS03090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIT1002_RS03110	COG0271	Belongs to the BolA IbaG family
MIT1002_RS03125	COG3707	response regulator
MIT1002_RS03135	COG0659	secondary active sulfate transmembrane transporter activity
MIT1002_RS03140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIT1002_RS03145	COG2146	nitrite reductase [NAD(P)H] activity
MIT1002_RS03150	COG0243	molybdopterin cofactor binding
MIT1002_RS03155	COG1648	precorrin-2 dehydrogenase activity
MIT1002_RS03155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIT1002_RS03165	COG0737	Belongs to the 5'-nucleotidase family
MIT1002_RS03170	COG3706	GGDEF domain
MIT1002_RS03170	COG5001	Diguanylate cyclase
MIT1002_RS03170	COG4251	negative regulation of phosphorylation
MIT1002_RS03170	COG2203	Gaf domain
MIT1002_RS03180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIT1002_RS03180	COG1116	anion transmembrane transporter activity
MIT1002_RS03190	COG1116	anion transmembrane transporter activity
MIT1002_RS03205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIT1002_RS03210	COG4206	TonB-dependent receptor
MIT1002_RS03215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIT1002_RS03220	COG0348	domain, Protein
MIT1002_RS03235	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS03250	COG4948	Mandelate Racemase Muconate Lactonizing
MIT1002_RS03265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS03270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS03290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIT1002_RS03295	COG0358	DNA primase activity
MIT1002_RS03320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MIT1002_RS03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIT1002_RS03340	COG0537	adenosine 5'-monophosphoramidase activity
MIT1002_RS03355	COG3135	benzoate transporter
MIT1002_RS03365	COG4772	TonB-dependent receptor
MIT1002_RS03370	COG1304	FMN binding
MIT1002_RS03385	COG0723	plastoquinol--plastocyanin reductase activity
MIT1002_RS03395	COG3284	Transcriptional regulator
MIT1002_RS03410	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS03460	COG2201	protein-glutamate methylesterase activity
MIT1002_RS03500	COG1396	sequence-specific DNA binding
MIT1002_RS03505	COG2974	May be involved in recombination
MIT1002_RS03510	COG4191	Histidine kinase
MIT1002_RS03510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS03515	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS03520	COG5002	protein histidine kinase activity
MIT1002_RS03550	COG0811	peptide transport
MIT1002_RS03555	COG0811	peptide transport
MIT1002_RS03560	COG0848	biopolymer transport protein
MIT1002_RS03565	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MIT1002_RS03575	COG3437	response regulator, receiver
MIT1002_RS03595	COG2133	pyrroloquinoline quinone binding
MIT1002_RS03600	COG1049	propionate catabolic process, 2-methylcitrate cycle
MIT1002_RS03635	COG0527	aspartate kinase activity
MIT1002_RS03645	COG0840	transmembrane signaling receptor activity
MIT1002_RS03650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIT1002_RS03655	COG2967	ApaG domain
MIT1002_RS03665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIT1002_RS03670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_RS03675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MIT1002_RS03680	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MIT1002_RS03690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIT1002_RS03710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MIT1002_RS03725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIT1002_RS03730	COG3956	TIGRFAM MazG family protein
MIT1002_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_RS03785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIT1002_RS03815	COG0642	Histidine kinase
MIT1002_RS03835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MIT1002_RS03840	COG0723	plastoquinol--plastocyanin reductase activity
MIT1002_RS03845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIT1002_RS03850	COG2857	Cytochrome c1
MIT1002_RS03855	COG0625	glutathione transferase activity
MIT1002_RS03860	COG2969	positive regulation of protein catabolic process
MIT1002_RS03875	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS03880	COG2239	Acts as a magnesium transporter
MIT1002_RS03885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MIT1002_RS03905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIT1002_RS03910	COG1137	ATPase activity
MIT1002_RS03915	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MIT1002_RS03925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIT1002_RS03940	COG1127	ABC transporter
MIT1002_RS03945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIT1002_RS03950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIT1002_RS03955	COG2854	intermembrane phospholipid transfer
MIT1002_RS03965	COG5007	Belongs to the BolA IbaG family
MIT1002_RS03975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIT1002_RS03980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIT1002_RS03990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MIT1002_RS04020	COG2308	Evidence 4 Homologs of previously reported genes of
MIT1002_RS04025	COG1305	Transglutaminase-like
MIT1002_RS04060	COG4771	TonB-dependent receptor
MIT1002_RS04065	COG0697	spore germination
MIT1002_RS04075	COG2205	protein histidine kinase activity
MIT1002_RS04075	COG0784	Response regulator, receiver
MIT1002_RS04100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIT1002_RS04110	COG0126	phosphoglycerate kinase activity
MIT1002_RS04115	COG3588	fructose-bisphosphate aldolase
MIT1002_RS04120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MIT1002_RS04135	COG5002	protein histidine kinase activity
MIT1002_RS04155	COG1538	Outer membrane efflux protein
MIT1002_RS04165	COG1506	peptidase
MIT1002_RS04165	COG4946	Tricorn protease homolog
MIT1002_RS04165	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_RS04170	COG0248	Ppx GppA phosphatase
MIT1002_RS04175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MIT1002_RS04180	COG2716	regulation of RNA biosynthetic process
MIT1002_RS04185	COG0573	inorganic phosphate transmembrane transporter activity
MIT1002_RS04195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MIT1002_RS04210	COG0306	phosphate transporter
MIT1002_RS04220	COG0583	DNA-binding transcription factor activity
MIT1002_RS04245	COG1272	protein, Hemolysin III
MIT1002_RS04250	COG1846	Transcriptional regulator
MIT1002_RS04255	COG1764	response to oxidative stress
MIT1002_RS04270	COG1739	Uncharacterized protein family UPF0029
MIT1002_RS04295	COG0583	DNA-binding transcription factor activity
MIT1002_RS04300	COG4989	oxidoreductase activity
MIT1002_RS04315	COG0420	3'-5' exonuclease activity
MIT1002_RS04320	COG0419	ATPase involved in DNA repair
MIT1002_RS04330	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIT1002_RS04350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIT1002_RS04355	COG2986	histidine ammonia-lyase
MIT1002_RS04370	COG2971	BadF BadG BcrA BcrD
MIT1002_RS04375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIT1002_RS04385	COG0488	(ABC) transporter
MIT1002_RS04415	COG0668	transmembrane transport
MIT1002_RS04430	COG2814	Major facilitator Superfamily
MIT1002_RS04435	COG0582	viral genome integration into host DNA
MIT1002_RS04460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIT1002_RS04525	COG1201	RNA secondary structure unwinding
MIT1002_RS04575	COG1346	cytolysis
MIT1002_RS04605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIT1002_RS04610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIT1002_RS04615	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS04635	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_RS04635	COG3267	Type II secretory pathway component ExeA
MIT1002_RS04660	COG0473	3-isopropylmalate dehydrogenase activity
MIT1002_RS04665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIT1002_RS04680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIT1002_RS04700	COG2271	Major facilitator Superfamily
MIT1002_RS04705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_RS04710	COG0800	Aldolase
MIT1002_RS04715	COG2186	Transcriptional regulator
MIT1002_RS04765	COG4555	ABC transporter
MIT1002_RS04770	COG1668	transmembrane transport
MIT1002_RS04785	COG4133	protoheme IX ABC transporter activity
MIT1002_RS04790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_RS04795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_RS04800	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIT1002_RS04810	COG1138	Cytochrome C-type biogenesis protein
MIT1002_RS04830	COG2853	Lipoprotein
MIT1002_RS04835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIT1002_RS04875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIT1002_RS04890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MIT1002_RS04895	COG1555	photosystem II stabilization
MIT1002_RS04895	COG1596	polysaccharide export
MIT1002_RS04900	COG0473	3-isopropylmalate dehydrogenase activity
MIT1002_RS04915	COG1611	Belongs to the LOG family
MIT1002_RS04965	COG0564	pseudouridine synthase activity
MIT1002_RS04980	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MIT1002_RS04985	COG0024	Methionine aminopeptidase
MIT1002_RS04990	COG0052	Belongs to the universal ribosomal protein uS2 family
MIT1002_RS05000	COG0528	UMP kinase activity
MIT1002_RS05010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIT1002_RS05015	COG0575	Belongs to the CDS family
MIT1002_RS05025	COG0750	zinc metalloprotease
MIT1002_RS05040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIT1002_RS05045	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIT1002_RS05060	COG0587	DNA-directed DNA polymerase activity
MIT1002_RS05065	COG0825	malonyl-CoA metabolic process
MIT1002_RS05070	COG0037	tRNA processing
MIT1002_RS05105	COG0047	phosphoribosylformylglycinamidine synthase activity
MIT1002_RS05105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIT1002_RS05115	COG2840	Smr protein MutS2
MIT1002_RS05155	COG0835	chemotaxis
MIT1002_RS05155	COG0784	Response regulator, receiver
MIT1002_RS05160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MIT1002_RS05165	COG1815	bacterial-type flagellum-dependent cell motility
MIT1002_RS05180	COG1749	Flagellar hook protein flgE
MIT1002_RS05185	COG4787	bacterial-type flagellum-dependent cell motility
MIT1002_RS05205	COG1705	Flagellar rod assembly protein muramidase FlgJ
MIT1002_RS05205	COG3951	Flagellar rod assembly protein muramidase FlgJ
MIT1002_RS05210	COG1256	bacterial-type flagellum assembly
MIT1002_RS05235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIT1002_RS05240	COG1334	flagellar protein FlaG
MIT1002_RS05245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MIT1002_RS05290	COG0673	inositol 2-dehydrogenase activity
MIT1002_RS05295	COG1083	cytidylyl-transferase
MIT1002_RS05310	COG2089	acid synthase
MIT1002_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS05325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIT1002_RS05340	COG1086	Polysaccharide biosynthesis protein
MIT1002_RS05355	COG3475	LICD family
MIT1002_RS05360	COG2089	acid synthase
MIT1002_RS05370	COG1083	cytidylyl-transferase
MIT1002_RS05375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIT1002_RS05400	COG1677	Flagellar hook-basal body complex protein FliE
MIT1002_RS05405	COG1766	The M ring may be actively involved in energy transduction
MIT1002_RS05410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MIT1002_RS05460	COG1987	bacterial-type flagellum assembly
MIT1002_RS05480	COG2989	Protein conserved in bacteria
MIT1002_RS05485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIT1002_RS05510	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MIT1002_RS05515	COG0643	Histidine kinase
MIT1002_RS05515	COG0784	Response regulator, receiver
MIT1002_RS05515	COG2198	Histidine kinase
MIT1002_RS05520	COG2201	protein-glutamate methylesterase activity
MIT1002_RS05525	COG1192	Involved in chromosome partitioning
MIT1002_RS05535	COG0835	chemotaxis
MIT1002_RS05550	COG1410	methionine synthase
MIT1002_RS05550	COG0646	methionine synthase
MIT1002_RS05555	COG0646	methionine synthase
MIT1002_RS05555	COG1410	methionine synthase
MIT1002_RS05565	COG3123	guanosine phosphorylase activity
MIT1002_RS05575	COG0583	DNA-binding transcription factor activity
MIT1002_RS05580	COG0583	DNA-binding transcription factor activity
MIT1002_RS05585	COG0288	reversible hydration of carbon dioxide
MIT1002_RS05590	COG0659	secondary active sulfate transmembrane transporter activity
MIT1002_RS05600	COG1309	transcriptional regulator
MIT1002_RS05605	COG3590	peptidase
MIT1002_RS05615	COG2137	regulation of response to DNA damage stimulus
MIT1002_RS05620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIT1002_RS05645	COG1607	acyl-coa hydrolase
MIT1002_RS05655	COG0511	ligase activity, forming carbon-carbon bonds
MIT1002_RS05655	COG5016	pyruvate
MIT1002_RS05660	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MIT1002_RS05665	COG4172	Belongs to the ABC transporter superfamily
MIT1002_RS05675	COG4171	peptide transport system, permease
MIT1002_RS05680	COG4168	peptide transport system, permease
MIT1002_RS05685	COG0747	negative chemotaxis
MIT1002_RS05690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MIT1002_RS05695	COG1842	Phage shock protein A
MIT1002_RS05725	COG0625	glutathione transferase activity
MIT1002_RS05730	COG1522	sequence-specific DNA binding
MIT1002_RS05795	COG0811	peptide transport
MIT1002_RS05800	COG0811	peptide transport
MIT1002_RS05805	COG0848	biopolymer transport protein
MIT1002_RS05820	COG1444	tRNA N-acetyltransferase activity
MIT1002_RS05860	COG0456	acetyltransferase
MIT1002_RS05870	COG0583	DNA-binding transcription factor activity
MIT1002_RS05875	COG2814	Major facilitator Superfamily
MIT1002_RS05880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_RS05885	COG0656	L-ascorbic acid biosynthetic process
MIT1002_RS05905	COG1846	Transcriptional regulator
MIT1002_RS05915	COG3275	phosphorelay sensor kinase activity
MIT1002_RS05920	COG1966	Carbon starvation protein
MIT1002_RS05940	COG0457	Tetratricopeptide repeat
MIT1002_RS05955	COG2197	response regulator
MIT1002_RS05965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MIT1002_RS06000	COG0583	DNA-binding transcription factor activity
MIT1002_RS06005	COG0702	epimerase
MIT1002_RS06025	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS06040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MIT1002_RS06045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIT1002_RS06050	COG0564	pseudouridine synthase activity
MIT1002_RS06060	COG0612	Peptidase, M16
MIT1002_RS06065	COG2918	glutathione biosynthetic process
MIT1002_RS06090	COG2840	Smr protein MutS2
MIT1002_RS06095	COG2890	protein-(glutamine-N5) methyltransferase activity
MIT1002_RS06110	COG2719	SpoVR family
MIT1002_RS06115	COG2718	Belongs to the UPF0229 family
MIT1002_RS06120	COG2766	serine protein kinase
MIT1002_RS06125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIT1002_RS06130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIT1002_RS06135	COG4771	TonB-dependent receptor
MIT1002_RS06160	COG0450	alkyl hydroperoxide reductase
MIT1002_RS06165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIT1002_RS06170	COG2885	chlorophyll binding
MIT1002_RS06175	COG0584	glycerophosphoryl diester phosphodiesterase
MIT1002_RS06180	COG0346	lactoylglutathione lyase activity
MIT1002_RS06185	COG4221	oxidoreductase activity
MIT1002_RS06190	COG1278	Cold shock
MIT1002_RS06205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIT1002_RS06210	COG4660	Part of a membrane complex involved in electron transport
MIT1002_RS06215	COG4659	FMN binding
MIT1002_RS06220	COG4658	electron transport chain
MIT1002_RS06225	COG4656	Part of a membrane complex involved in electron transport
MIT1002_RS06230	COG2878	Part of a membrane complex involved in electron transport
MIT1002_RS06235	COG4657	Part of a membrane complex involved in electron transport
MIT1002_RS06250	COG0534	Mate efflux family protein
MIT1002_RS06255	COG0556	nucleotide-excision repair
MIT1002_RS06270	COG0602	queuosine metabolic process
MIT1002_RS06280	COG0367	asparagine synthase
MIT1002_RS06300	COG0471	metal ion transport
MIT1002_RS06300	COG3273	potassium ion transport
MIT1002_RS06315	COG0529	Catalyzes the synthesis of activated sulfate
MIT1002_RS06320	COG0175	sulfate reduction
MIT1002_RS06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_RS06355	COG2304	oxidoreductase activity
MIT1002_RS06375	COG0714	Associated with various cellular activities
MIT1002_RS06385	COG1024	Enoyl-CoA hydratase
MIT1002_RS06385	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIT1002_RS06405	COG1025	Belongs to the peptidase M16 family
MIT1002_RS06410	COG2062	phosphohistidine phosphatase, SixA
MIT1002_RS06420	COG4536	flavin adenine dinucleotide binding
MIT1002_RS06425	COG4137	Cytochrome C assembly protein
MIT1002_RS06430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIT1002_RS06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS06475	COG1132	(ABC) transporter
MIT1002_RS06490	COG0228	four-way junction DNA binding
MIT1002_RS06495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIT1002_RS06500	COG0336	Belongs to the RNA methyltransferase TrmD family
MIT1002_RS06505	COG0335	large ribosomal subunit rRNA binding
MIT1002_RS06510	COG2860	membrane
MIT1002_RS06520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIT1002_RS06525	COG0287	Prephenate dehydrogenase
MIT1002_RS06525	COG1605	Chorismate mutase
MIT1002_RS06555	COG0077	Prephenate dehydratase
MIT1002_RS06555	COG1605	Chorismate mutase
MIT1002_RS06560	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS06565	COG0023	Translation Initiation Factor
MIT1002_RS06595	COG2205	protein histidine kinase activity
MIT1002_RS06605	COG2204	response regulator
MIT1002_RS06620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIT1002_RS06625	COG0494	nUDIX hydrolase
MIT1002_RS06630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIT1002_RS06635	COG0632	four-way junction helicase activity
MIT1002_RS06640	COG2255	four-way junction helicase activity
MIT1002_RS06645	COG0824	Thioesterase
MIT1002_RS06650	COG0811	peptide transport
MIT1002_RS06665	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_RS06670	COG2885	chlorophyll binding
MIT1002_RS06675	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MIT1002_RS06695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIT1002_RS06730	COG0328	RNA-DNA hybrid ribonuclease activity
MIT1002_RS06745	COG4667	esterase of the alpha-beta hydrolase superfamily
MIT1002_RS06750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIT1002_RS06760	COG2205	protein histidine kinase activity
MIT1002_RS06760	COG0784	Response regulator, receiver
MIT1002_RS06775	COG3038	cytochrome b561
MIT1002_RS06795	COG1451	nucleotide metabolic process
MIT1002_RS06805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS06815	COG1309	transcriptional regulator
MIT1002_RS06820	COG4774	siderophore transport
MIT1002_RS06840	COG3706	GGDEF domain
MIT1002_RS06850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIT1002_RS06850	COG3008	intermembrane lipid transfer
MIT1002_RS06855	COG2995	paraquat-inducible protein a
MIT1002_RS06865	COG0017	Asparaginyl-tRNA synthetase
MIT1002_RS06880	COG0189	ligase activity
MIT1002_RS06915	COG2226	methyltransferase
MIT1002_RS06930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIT1002_RS06935	COG4139	cobalamin transport
MIT1002_RS06940	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
MIT1002_RS06945	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MIT1002_RS06950	COG2205	protein histidine kinase activity
MIT1002_RS06955	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS06960	COG0569	domain protein
MIT1002_RS06965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIT1002_RS06980	COG5265	(ABC) transporter
MIT1002_RS06985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIT1002_RS06995	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS07015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIT1002_RS07060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_RS07075	COG2755	lipolytic protein G-D-S-L family
MIT1002_RS07080	COG4181	ATPase activity
MIT1002_RS07085	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MIT1002_RS07090	COG1090	epimerase
MIT1002_RS07095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIT1002_RS07100	COG0628	permease
MIT1002_RS07125	COG2350	Protein conserved in bacteria
MIT1002_RS07130	COG0159	tryptophan synthase activity
MIT1002_RS07140	COG0134	indole-3-glycerol-phosphate synthase activity
MIT1002_RS07140	COG0135	phosphoribosylanthranilate isomerase activity
MIT1002_RS07145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIT1002_RS07155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIT1002_RS07160	COG0613	PHP domain protein
MIT1002_RS07165	COG0009	L-threonylcarbamoyladenylate synthase
MIT1002_RS07175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIT1002_RS07185	COG0656	L-ascorbic acid biosynthetic process
MIT1002_RS07190	COG0110	maltose O-acetyltransferase activity
MIT1002_RS07205	COG2733	membrane
MIT1002_RS07210	COG0500	methyltransferase
MIT1002_RS07215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_RS07220	COG0497	DNA recombination
MIT1002_RS07225	COG0783	Belongs to the Dps family
MIT1002_RS07230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIT1002_RS07240	COG1454	alcohol dehydrogenase
MIT1002_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS07255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIT1002_RS07260	COG2610	gluconate transmembrane transporter activity
MIT1002_RS07265	COG4771	TonB-dependent receptor
MIT1002_RS07280	COG0784	Response regulator, receiver
MIT1002_RS07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS07280	COG2198	Histidine kinase
MIT1002_RS07280	COG2205	protein histidine kinase activity
MIT1002_RS07290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIT1002_RS07300	COG0484	heat shock protein binding
MIT1002_RS07305	COG3909	cytochrome
MIT1002_RS07320	COG2200	EAL domain
MIT1002_RS07320	COG2199	diguanylate cyclase activity
MIT1002_RS07320	COG2202	Pas domain
MIT1002_RS07335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MIT1002_RS07345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MIT1002_RS07350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_RS07375	COG0071	Belongs to the small heat shock protein (HSP20) family
MIT1002_RS07385	COG0280	phosphate acetyltransferase
MIT1002_RS07385	COG0857	belongs to the CobB CobQ family
MIT1002_RS07390	COG1228	amidohydrolase
MIT1002_RS07395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MIT1002_RS07400	COG4535	Mg2 and Co2 transporter CorC
MIT1002_RS07410	COG1702	phosphate starvation-inducible protein PhoH
MIT1002_RS07420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_RS07460	COG1607	acyl-coa hydrolase
MIT1002_RS07465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIT1002_RS07475	COG1115	amino acid carrier protein
MIT1002_RS07525	COG0012	GTP binding
MIT1002_RS07540	COG1064	alcohol dehydrogenase
MIT1002_RS07550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIT1002_RS07560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIT1002_RS07570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIT1002_RS07580	COG2890	protein-(glutamine-N5) methyltransferase activity
MIT1002_RS07585	COG0784	Response regulator, receiver
MIT1002_RS07585	COG3437	response regulator, receiver
MIT1002_RS07595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MIT1002_RS07605	COG0583	DNA-binding transcription factor activity
MIT1002_RS07615	COG2363	Small membrane protein
MIT1002_RS07635	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MIT1002_RS07640	COG0515	serine threonine protein kinase
MIT1002_RS07645	COG2116	formate transmembrane transporter activity
MIT1002_RS07660	COG0714	Associated with various cellular activities
MIT1002_RS07665	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MIT1002_RS07670	COG0033	Phosphoglucomutase
MIT1002_RS07675	COG0058	SHG alpha-glucan phosphorylase activity
MIT1002_RS07685	COG2988	succinylglutamate desuccinylase activity
MIT1002_RS07700	COG1301	dicarboxylic acid transport
MIT1002_RS07720	COG1393	Belongs to the ArsC family
MIT1002_RS07745	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MIT1002_RS07765	COG3300	MHYT domain
MIT1002_RS07765	COG5001	Diguanylate cyclase
MIT1002_RS07795	COG2249	NAD(P)H dehydrogenase (quinone) activity
MIT1002_RS07820	COG1733	regulation of RNA biosynthetic process
MIT1002_RS07830	COG5001	Diguanylate cyclase
MIT1002_RS07830	COG3447	MASE1 domain protein
MIT1002_RS07830	COG5002	protein histidine kinase activity
MIT1002_RS07840	COG0402	S-adenosylhomocysteine deaminase activity
MIT1002_RS07845	COG2351	hydroxyisourate hydrolase activity
MIT1002_RS07860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIT1002_RS07870	COG1309	transcriptional regulator
MIT1002_RS07885	COG2252	PERMEase
MIT1002_RS07890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_RS07910	COG2205	protein histidine kinase activity
MIT1002_RS07910	COG0784	Response regulator, receiver
MIT1002_RS07925	COG2233	PERMEase
MIT1002_RS07930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_RS07945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MIT1002_RS07950	COG0730	response to heat
MIT1002_RS07960	COG0154	amidase activity
MIT1002_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS07995	COG3001	Fructosamine kinase
MIT1002_RS08005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIT1002_RS08025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIT1002_RS08035	COG1596	polysaccharide export
MIT1002_RS08040	COG0489	protein tyrosine kinase activity
MIT1002_RS08045	COG4464	protein tyrosine phosphatase activity
MIT1002_RS08080	COG0438	transferase activity, transferring glycosyl groups
MIT1002_RS08090	COG1045	serine acetyltransferase
MIT1002_RS08105	COG1215	transferase activity, transferring glycosyl groups
MIT1002_RS08110	COG1216	Glycosyl transferase, family 2
MIT1002_RS08115	COG2244	polysaccharide biosynthetic process
MIT1002_RS08155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_RS08155	COG0072	phenylalanine-tRNA ligase activity
MIT1002_RS08180	COG1472	Belongs to the glycosyl hydrolase 3 family
MIT1002_RS08185	COG2096	Adenosyltransferase
MIT1002_RS08195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIT1002_RS08205	COG4591	ABC-type transport system involved in lipoprotein release permease component
MIT1002_RS08230	COG0708	Exodeoxyribonuclease III
MIT1002_RS08265	COG2814	Major facilitator Superfamily
MIT1002_RS08300	COG4770	biotin carboxylase activity
MIT1002_RS08305	COG1024	Enoyl-CoA hydratase
MIT1002_RS08310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MIT1002_RS08315	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS08320	COG0789	Transcriptional regulator
MIT1002_RS08325	COG0183	Belongs to the thiolase family
MIT1002_RS08350	COG2925	Exonuclease
MIT1002_RS08355	COG2205	protein histidine kinase activity
MIT1002_RS08355	COG0784	Response regulator, receiver
MIT1002_RS08355	COG5002	protein histidine kinase activity
MIT1002_RS08395	COG1643	Atp-dependent helicase
MIT1002_RS08415	COG0604	alcohol dehydrogenase
MIT1002_RS08415	COG3321	synthase
MIT1002_RS08420	COG0328	RNA-DNA hybrid ribonuclease activity
MIT1002_RS08425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIT1002_RS08455	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MIT1002_RS08460	COG1136	(ABC) transporter
MIT1002_RS08465	COG4591	ABC-type transport system involved in lipoprotein release permease component
MIT1002_RS08470	COG1301	dicarboxylic acid transport
MIT1002_RS08480	COG3724	N-succinylarginine dihydrolase activity
MIT1002_RS08485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIT1002_RS08490	COG3122	Protein conserved in bacteria
MIT1002_RS08500	COG0583	DNA-binding transcription factor activity
MIT1002_RS08505	COG0746	molybdenum cofactor guanylyltransferase activity
MIT1002_RS08510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIT1002_RS08515	COG0243	molybdopterin cofactor binding
MIT1002_RS08525	COG0625	glutathione transferase activity
MIT1002_RS08540	COG2153	protein acetylation
MIT1002_RS08555	COG5002	protein histidine kinase activity
MIT1002_RS08565	COG1530	ribonuclease E activity
MIT1002_RS08570	COG0564	pseudouridine synthase activity
MIT1002_RS08575	COG0546	phosphoglycolate phosphatase activity
MIT1002_RS08580	COG0424	maF-like protein
MIT1002_RS08585	COG1399	metal-binding, possibly nucleic acid-binding protein
MIT1002_RS08595	COG0416	fatty acid biosynthetic process
MIT1002_RS08600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIT1002_RS08605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MIT1002_RS08615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIT1002_RS08620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIT1002_RS08625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MIT1002_RS08630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIT1002_RS08645	COG0084	hydrolase, TatD family'
MIT1002_RS08650	COG0259	pyridoxamine-phosphate oxidase activity
MIT1002_RS08655	COG0702	epimerase
MIT1002_RS08660	COG3706	GGDEF domain
MIT1002_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS08690	COG0596	Alpha beta hydrolase
MIT1002_RS08695	COG1024	Enoyl-CoA hydratase
MIT1002_RS08695	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIT1002_RS08700	COG0183	Belongs to the thiolase family
MIT1002_RS08705	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS08710	COG0596	Alpha beta hydrolase
MIT1002_RS08725	COG2390	Transcriptional regulator
MIT1002_RS08730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIT1002_RS08740	COG0246	Mannitol dehydrogenase
MIT1002_RS08755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MIT1002_RS08760	COG0523	cobalamin synthesis protein
MIT1002_RS08765	COG0247	lactate metabolic process
MIT1002_RS08765	COG0277	FAD linked oxidase domain protein
MIT1002_RS08790	COG0668	transmembrane transport
MIT1002_RS08795	COG4771	TonB-dependent receptor
MIT1002_RS08820	COG2205	protein histidine kinase activity
MIT1002_RS08820	COG2198	Histidine kinase
MIT1002_RS08820	COG0784	Response regulator, receiver
MIT1002_RS08825	COG3437	response regulator, receiver
MIT1002_RS08835	COG0195	Participates in both transcription termination and antitermination
MIT1002_RS08850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIT1002_RS08865	COG5001	Diguanylate cyclase
MIT1002_RS08865	COG3300	MHYT domain
MIT1002_RS08870	COG1187	pseudouridine synthase activity
MIT1002_RS08880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIT1002_RS08880	COG3153	acetyltransferase
MIT1002_RS08960	COG1032	radical SAM domain protein
MIT1002_RS08975	COG4771	TonB-dependent receptor
MIT1002_RS08980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_RS08990	COG4134	Bacterial extracellular solute-binding protein
MIT1002_RS09000	COG4136	ATPase activity
MIT1002_RS09005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIT1002_RS09020	COG0604	alcohol dehydrogenase
MIT1002_RS09045	COG0583	DNA-binding transcription factor activity
MIT1002_RS09070	COG1131	(ABC) transporter
MIT1002_RS09090	COG0582	viral genome integration into host DNA
MIT1002_RS09105	COG3012	SEC-C Motif Domain Protein
MIT1002_RS09125	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS09135	COG2867	negative regulation of translational initiation
MIT1002_RS09140	COG2914	Belongs to the UPF0125 (RnfH) family
MIT1002_RS09150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIT1002_RS09155	COG4771	TonB-dependent receptor
MIT1002_RS09160	COG0457	Tetratricopeptide repeat
MIT1002_RS09180	COG0574	Belongs to the PEP-utilizing enzyme family
MIT1002_RS09180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIT1002_RS09215	COG2850	peptidyl-arginine hydroxylation
MIT1002_RS09225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIT1002_RS09230	COG2915	High frequency lysogenization protein hflD homolog
MIT1002_RS09240	COG1187	pseudouridine synthase activity
MIT1002_RS09250	COG1278	Cold shock
MIT1002_RS09255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MIT1002_RS09260	COG0542	response to heat
MIT1002_RS09265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIT1002_RS09270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MIT1002_RS09275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MIT1002_RS09280	COG0492	ferredoxin-NADP+ reductase activity
MIT1002_RS09285	COG3092	negative regulation of chromosome organization
MIT1002_RS09290	COG3091	SprT-like family
MIT1002_RS09295	COG0616	signal peptide processing
MIT1002_RS09310	COG0778	Nitroreductase
MIT1002_RS09320	COG0252	asparaginase activity
MIT1002_RS09325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIT1002_RS09330	COG0321	lipoyl(octanoyl) transferase activity
MIT1002_RS09335	COG2921	Belongs to the UPF0250 family
MIT1002_RS09340	COG1686	Belongs to the peptidase S11 family
MIT1002_RS09345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIT1002_RS09350	COG0772	Belongs to the SEDS family
MIT1002_RS09355	COG0768	penicillin binding
MIT1002_RS09360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIT1002_RS09365	COG0799	negative regulation of ribosome biogenesis
MIT1002_RS09370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIT1002_RS09375	COG1466	dna polymerase III delta subunit
MIT1002_RS09380	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MIT1002_RS09385	COG0495	leucyl-tRNA aminoacylation
MIT1002_RS09395	COG1067	ATP-dependent peptidase activity
MIT1002_RS09415	COG1534	Rna-binding protein
MIT1002_RS09420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MIT1002_RS09425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIT1002_RS09430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIT1002_RS09435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIT1002_RS09440	COG0149	triose-phosphate isomerase activity
MIT1002_RS09445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIT1002_RS09475	COG1803	Methylglyoxal synthase
MIT1002_RS09475	COG1597	lipid kinase activity
MIT1002_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS09490	COG0561	phosphatase activity
MIT1002_RS09505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_RS09510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIT1002_RS09515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIT1002_RS09530	COG1185	polyribonucleotide nucleotidyltransferase activity
MIT1002_RS09565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIT1002_RS09610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIT1002_RS09685	COG2223	nitrite transmembrane transporter activity
MIT1002_RS09730	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MIT1002_RS09735	COG1196	nuclear chromosome segregation
MIT1002_RS09745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIT1002_RS09760	COG1132	(ABC) transporter
MIT1002_RS09765	COG1663	tetraacyldisaccharide 4'-kinase activity
MIT1002_RS09800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIT1002_RS09805	COG0435	Glutathione S-transferase
MIT1002_RS09810	COG1741	Belongs to the pirin family
MIT1002_RS09830	COG0372	Belongs to the citrate synthase family
MIT1002_RS09840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MIT1002_RS09845	COG1053	succinate dehydrogenase
MIT1002_RS09850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MIT1002_RS09855	COG0567	Dehydrogenase, E1 component
MIT1002_RS09860	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_RS09895	COG4667	esterase of the alpha-beta hydrolase superfamily
MIT1002_RS09915	COG0366	Alpha amylase catalytic
MIT1002_RS09930	COG1609	Transcriptional regulator
MIT1002_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS09945	COG2267	carboxylic ester hydrolase activity
MIT1002_RS09955	COG0616	signal peptide processing
MIT1002_RS09970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIT1002_RS09975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIT1002_RS09980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIT1002_RS09985	COG0386	Belongs to the glutathione peroxidase family
MIT1002_RS09990	COG2084	Dehydrogenase
MIT1002_RS10000	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS10005	COG1024	Enoyl-CoA hydratase
MIT1002_RS10010	COG2226	methyltransferase
MIT1002_RS10015	COG3083	sulfuric ester hydrolase activity
MIT1002_RS10020	COG3082	Protein of unknown function (DUF1414)
MIT1002_RS10025	COG3081	Nucleoid-associated protein
MIT1002_RS10035	COG0741	lytic transglycosylase activity
MIT1002_RS10035	COG0739	heme binding
MIT1002_RS10035	COG1196	nuclear chromosome segregation
MIT1002_RS10055	COG3275	phosphorelay sensor kinase activity
MIT1002_RS10060	COG3279	Response regulator of the LytR AlgR family
MIT1002_RS10065	COG0205	6-phosphofructokinase activity
MIT1002_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS10080	COG2205	protein histidine kinase activity
MIT1002_RS10090	COG1054	Belongs to the UPF0176 family
MIT1002_RS10130	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS10140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIT1002_RS10145	COG0583	DNA-binding transcription factor activity
MIT1002_RS10165	COG1760	l-serine dehydratase
MIT1002_RS10185	COG1322	Protein conserved in bacteria
MIT1002_RS10205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MIT1002_RS10210	COG0022	dehydrogenase e1 component
MIT1002_RS10220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIT1002_RS10225	COG0515	serine threonine protein kinase
MIT1002_RS10230	COG1946	Acyl-CoA thioesterase
MIT1002_RS10240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MIT1002_RS10250	COG1956	GAF domain-containing protein
MIT1002_RS10265	COG0793	Belongs to the peptidase S41A family
MIT1002_RS10270	COG0733	neurotransmitter:sodium symporter activity
MIT1002_RS10275	COG1757	Na H antiporter
MIT1002_RS10280	COG0308	aminopeptidase N
MIT1002_RS10315	COG0167	dihydroorotate dehydrogenase activity
MIT1002_RS10330	COG0488	(ABC) transporter
MIT1002_RS10340	COG3130	regulation of translation
MIT1002_RS10345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIT1002_RS10355	COG0415	Belongs to the DNA photolyase family
MIT1002_RS10360	COG0415	Belongs to the DNA photolyase family
MIT1002_RS10365	COG0415	Belongs to the DNA photolyase family
MIT1002_RS10370	COG3046	protein related to deoxyribodipyrimidine photolyase
MIT1002_RS10385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_RS10400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MIT1002_RS10405	COG0589	response to stress
MIT1002_RS10415	COG0069	glutamate synthase activity
MIT1002_RS10430	COG2193	ferroxidase activity
MIT1002_RS10440	COG3278	Belongs to the heme-copper respiratory oxidase family
MIT1002_RS10455	COG2010	Cytochrome c
MIT1002_RS10480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIT1002_RS10485	COG0589	response to stress
MIT1002_RS10490	COG0037	tRNA processing
MIT1002_RS10495	COG1752	Esterase of the alpha-beta hydrolase superfamily
MIT1002_RS10515	COG1280	lysine exporter protein (LysE YggA)
MIT1002_RS10525	COG2897	thiosulfate sulfurtransferase activity
MIT1002_RS10530	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MIT1002_RS10535	COG3148	PFAM DTW domain containing protein
MIT1002_RS10560	COG0322	excinuclease ABC activity
MIT1002_RS10565	COG2197	response regulator
MIT1002_RS10570	COG1741	Belongs to the pirin family
MIT1002_RS10575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_RS10580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MIT1002_RS10600	COG3384	dioxygenase
MIT1002_RS10605	COG2259	Doxx family
MIT1002_RS10610	COG0583	DNA-binding transcription factor activity
MIT1002_RS10625	COG0670	Belongs to the BI1 family
MIT1002_RS10630	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MIT1002_RS10645	COG2920	part of a sulfur-relay system
MIT1002_RS10665	COG4206	TonB-dependent receptor
MIT1002_RS10665	COG4206	TonB-dependent receptor
MIT1002_RS10680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIT1002_RS10685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIT1002_RS10690	COG0531	amino acid
MIT1002_RS10690	COG1674	ftsk spoiiie
MIT1002_RS10700	COG0686	Belongs to the AlaDH PNT family
MIT1002_RS10705	COG0284	orotidine-5'-phosphate decarboxylase activity
MIT1002_RS10710	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIT1002_RS10725	COG0776	regulation of translation
MIT1002_RS10730	COG0539	negative regulation of cytoplasmic translation
MIT1002_RS10735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MIT1002_RS10740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MIT1002_RS10745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIT1002_RS10755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIT1002_RS10760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIT1002_RS10765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIT1002_RS10770	COG0633	Ferredoxin
MIT1002_RS10775	COG4221	oxidoreductase activity
MIT1002_RS10815	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MIT1002_RS10820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIT1002_RS10835	COG4974	Belongs to the 'phage' integrase family
MIT1002_RS10855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIT1002_RS10915	COG4783	chaperone-mediated protein folding
MIT1002_RS10920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIT1002_RS10925	COG1393	Belongs to the ArsC family
MIT1002_RS10960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIT1002_RS10970	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS10995	COG0572	uridine kinase
MIT1002_RS11000	COG3769	mannosylglycerate metabolic process
MIT1002_RS11005	COG1215	transferase activity, transferring glycosyl groups
MIT1002_RS11020	COG0303	'Molybdopterin
MIT1002_RS11025	COG0534	Mate efflux family protein
MIT1002_RS11045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MIT1002_RS11100	COG3011	Protein conserved in bacteria
MIT1002_RS11140	COG0405	Gamma-glutamyltransferase
MIT1002_RS11145	COG1024	Enoyl-CoA hydratase
MIT1002_RS11205	COG1671	Belongs to the UPF0178 family
MIT1002_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS11220	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS11225	COG0662	Cupin 2, conserved barrel domain protein
MIT1002_RS11225	COG2207	Transcriptional regulator
MIT1002_RS11240	COG1505	serine-type exopeptidase activity
MIT1002_RS11280	COG0596	Alpha beta hydrolase
MIT1002_RS11290	COG0716	FMN binding
MIT1002_RS11300	COG0735	belongs to the Fur family
MIT1002_RS11310	COG1984	allophanate hydrolase subunit 2
MIT1002_RS11315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIT1002_RS11320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MIT1002_RS11325	COG2996	Protein conserved in bacteria
MIT1002_RS11330	COG1765	OsmC-like protein
MIT1002_RS11335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS11345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS11360	COG0436	Aminotransferase
MIT1002_RS11365	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MIT1002_RS11370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MIT1002_RS11400	COG0653	protein targeting
MIT1002_RS11405	COG0366	Alpha amylase catalytic
MIT1002_RS11410	COG0604	alcohol dehydrogenase
MIT1002_RS11420	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS11430	COG4771	TonB-dependent receptor
MIT1002_RS11455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MIT1002_RS11475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MIT1002_RS11480	COG0315	cyclic pyranopterin monophosphate synthase activity
MIT1002_RS11485	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIT1002_RS11490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MIT1002_RS11500	COG2423	ornithine cyclodeaminase activity
MIT1002_RS11505	COG0436	Aminotransferase
MIT1002_RS11510	COG1522	sequence-specific DNA binding
MIT1002_RS11525	COG0826	peptidase U32
MIT1002_RS11530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIT1002_RS11535	COG0436	Aminotransferase
MIT1002_RS11540	COG3268	Saccharopine dehydrogenase
MIT1002_RS11545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_RS11565	COG4771	TonB-dependent receptor
MIT1002_RS11610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIT1002_RS11620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIT1002_RS11625	COG1074	ATP-dependent DNA helicase activity
MIT1002_RS11630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MIT1002_RS11640	COG1022	Amp-dependent synthetase and ligase
MIT1002_RS11665	COG0583	DNA-binding transcription factor activity
MIT1002_RS11685	COG0640	Transcriptional regulator
MIT1002_RS11705	COG2204	response regulator
MIT1002_RS11715	COG4251	negative regulation of phosphorylation
MIT1002_RS11720	COG0784	Response regulator, receiver
MIT1002_RS11725	COG0784	Response regulator, receiver
MIT1002_RS11725	COG2205	protein histidine kinase activity
MIT1002_RS11780	COG3139	Protein of unknown function (DUF1315)
MIT1002_RS11790	COG1115	amino acid carrier protein
MIT1002_RS11795	COG2866	Carboxypeptidase
MIT1002_RS11815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIT1002_RS11825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIT1002_RS11830	COG1640	4-alpha-glucanotransferase
MIT1002_RS11840	COG0676	glucose-6-phosphate 1-epimerase activity
MIT1002_RS11845	COG0800	Aldolase
MIT1002_RS11855	COG0129	dihydroxy-acid dehydratase activity
MIT1002_RS11865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIT1002_RS11870	COG1737	Transcriptional regulator
MIT1002_RS11875	COG0469	pyruvate kinase activity
MIT1002_RS11900	COG2823	Periplasmic or secreted lipoprotein
MIT1002_RS11925	COG3665	Urea carboxylase-associated protein
MIT1002_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS11950	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MIT1002_RS11960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIT1002_RS11975	COG2721	sulfolactate sulfo-lyase activity
MIT1002_RS11980	COG1904	glucuronate isomerase
MIT1002_RS11985	COG0246	Mannitol dehydrogenase
MIT1002_RS11990	COG0800	Aldolase
MIT1002_RS11995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_RS12000	COG2755	lipolytic protein G-D-S-L family
MIT1002_RS12010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MIT1002_RS12020	COG4677	pectinesterase activity
MIT1002_RS12040	COG2356	endonuclease I
MIT1002_RS12065	COG0583	DNA-binding transcription factor activity
MIT1002_RS12075	COG1979	alcohol dehydrogenase
MIT1002_RS12080	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS12085	COG5001	Diguanylate cyclase
MIT1002_RS12085	COG4251	negative regulation of phosphorylation
MIT1002_RS12085	COG3706	GGDEF domain
MIT1002_RS12085	COG2203	Gaf domain
MIT1002_RS12095	COG0753	catalase activity
MIT1002_RS12100	COG3437	response regulator, receiver
MIT1002_RS12100	COG0784	Response regulator, receiver
MIT1002_RS12105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS12105	COG4191	Histidine kinase
MIT1002_RS12155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MIT1002_RS12185	COG0471	metal ion transport
MIT1002_RS12195	COG0489	protein tyrosine kinase activity
MIT1002_RS12200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_RS12200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIT1002_RS12205	COG0668	transmembrane transport
MIT1002_RS12210	COG2226	methyltransferase
MIT1002_RS12215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_RS12220	COG0741	lytic transglycosylase activity
MIT1002_RS12220	COG1388	LysM domain
MIT1002_RS12240	COG3138	arginine N-succinyltransferase
MIT1002_RS12245	COG0215	cysteine-tRNA ligase activity
MIT1002_RS12250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIT1002_RS12255	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIT1002_RS12265	COG2268	Band 7 protein
MIT1002_RS12270	COG0583	DNA-binding transcription factor activity
MIT1002_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS12290	COG1733	regulation of RNA biosynthetic process
MIT1002_RS12295	COG0604	alcohol dehydrogenase
MIT1002_RS12300	COG0861	Integral membrane protein TerC family
MIT1002_RS12305	COG1063	alcohol dehydrogenase
MIT1002_RS12310	COG0583	DNA-binding transcription factor activity
MIT1002_RS12345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIT1002_RS12350	COG1286	toxin biosynthetic process
MIT1002_RS12355	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MIT1002_RS12360	COG0285	dihydrofolate synthase activity
MIT1002_RS12385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_RS12400	COG0596	Alpha beta hydrolase
MIT1002_RS12410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIT1002_RS12415	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_RS12425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIT1002_RS12425	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIT1002_RS12465	COG0789	Transcriptional regulator
MIT1002_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS12480	COG1119	ATPase activity
MIT1002_RS12490	COG0523	cobalamin synthesis protein
MIT1002_RS12495	COG1917	Cupin 2, conserved barrel domain protein
MIT1002_RS12495	COG4977	sequence-specific DNA binding
MIT1002_RS12500	COG1335	isochorismatase
MIT1002_RS12510	COG2031	fatty acid transporter
MIT1002_RS12515	COG5002	protein histidine kinase activity
MIT1002_RS12515	COG2205	protein histidine kinase activity
MIT1002_RS12515	COG0784	Response regulator, receiver
MIT1002_RS12520	COG0612	Peptidase, M16
MIT1002_RS12535	COG3101	peptidyl-lysine hydroxylation
MIT1002_RS12560	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIT1002_RS12560	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS12585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MIT1002_RS12595	COG4399	Belongs to the UPF0754 family
MIT1002_RS12630	COG2186	Transcriptional regulator
MIT1002_RS12640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MIT1002_RS12645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIT1002_RS12650	COG2983	Belongs to the UPF0260 family
MIT1002_RS12655	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIT1002_RS12670	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MIT1002_RS12675	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_RS12680	COG2267	carboxylic ester hydrolase activity
MIT1002_RS12695	COG1214	PFAM Peptidase M22, glycoprotease
MIT1002_RS12700	COG1199	ATP-dependent helicase activity
MIT1002_RS12785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MIT1002_RS12790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIT1002_RS12795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_RS12800	COG0131	Imidazoleglycerol-phosphate dehydratase
MIT1002_RS12800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MIT1002_RS12805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIT1002_RS12835	COG2116	formate transmembrane transporter activity
MIT1002_RS12840	COG0612	Peptidase, M16
MIT1002_RS12865	COG0326	Molecular chaperone. Has ATPase activity
MIT1002_RS12870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIT1002_RS12940	COG0582	viral genome integration into host DNA
MIT1002_RS12955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIT1002_RS12960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIT1002_RS12975	COG3220	belongs to the UPF0276 family
MIT1002_RS13025	COG1183	phosphatidylcholine synthase activity
MIT1002_RS13045	COG0277	FAD linked oxidase domain protein
MIT1002_RS13050	COG1620	l-lactate permease
MIT1002_RS13070	COG0542	response to heat
MIT1002_RS13095	COG1595	DNA-templated transcription, initiation
MIT1002_RS13110	COG4221	oxidoreductase activity
MIT1002_RS13125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MIT1002_RS13135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MIT1002_RS13145	COG0142	geranyltranstransferase activity
MIT1002_RS13160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIT1002_RS13165	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIT1002_RS13175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIT1002_RS13190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIT1002_RS13190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIT1002_RS13205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIT1002_RS13210	COG0488	(ABC) transporter
MIT1002_RS13220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIT1002_RS13230	COG0560	Phosphoserine phosphatase
MIT1002_RS13240	COG0084	hydrolase, TatD family'
MIT1002_RS13255	COG0571	ribonuclease III activity
MIT1002_RS13285	COG1595	DNA-templated transcription, initiation
MIT1002_RS13290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIT1002_RS13305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MIT1002_RS13325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIT1002_RS13385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIT1002_RS13390	COG1047	Peptidyl-prolyl cis-trans
MIT1002_RS13400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIT1002_RS13405	COG0196	riboflavin kinase activity
MIT1002_RS13410	COG0728	peptidoglycan biosynthetic process
MIT1002_RS13415	COG0268	Binds directly to 16S ribosomal RNA
MIT1002_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS13435	COG0385	Bile acid
MIT1002_RS13460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_RS13465	COG0776	regulation of translation
MIT1002_RS13470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIT1002_RS13475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIT1002_RS13480	COG0740	serine-type endopeptidase activity
MIT1002_RS13485	COG0544	peptidyl-prolyl cis-trans isomerase activity
MIT1002_RS13540	COG1720	tRNA m6t6A37 methyltransferase activity
MIT1002_RS13550	COG1234	tRNA 3'-trailer cleavage
MIT1002_RS13560	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIT1002_RS13575	COG0516	GMP reductase activity
MIT1002_RS13575	COG0517	IMP dehydrogenase activity
MIT1002_RS13580	COG1570	exodeoxyribonuclease VII activity
MIT1002_RS13605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIT1002_RS13610	COG2976	Protein conserved in bacteria
MIT1002_RS13630	COG3063	Type IV pilus biogenesis stability protein PilW
MIT1002_RS13635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MIT1002_RS13645	COG2166	iron-sulfur cluster assembly
MIT1002_RS13660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIT1002_RS13665	COG0719	Fe-S assembly protein
MIT1002_RS13670	COG0396	ATPase activity
MIT1002_RS13675	COG0719	Fe-S assembly protein
MIT1002_RS13680	COG1104	cysteine desulfurase activity
MIT1002_RS13685	COG1959	2 iron, 2 sulfur cluster binding
MIT1002_RS13695	COG2072	flavoprotein involved in K transport
MIT1002_RS13700	COG1045	serine acetyltransferase
MIT1002_RS13705	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MIT1002_RS13710	COG0483	inositol monophosphate 1-phosphatase activity
MIT1002_RS13720	COG3279	Response regulator of the LytR AlgR family
MIT1002_RS13725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIT1002_RS13730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIT1002_RS13735	COG1862	Preprotein translocase
MIT1002_RS13740	COG0343	queuine tRNA-ribosyltransferase activity
MIT1002_RS13760	COG1842	Phage shock protein A
MIT1002_RS13765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MIT1002_RS13785	COG0754	glutathionylspermidine amidase activity
MIT1002_RS13815	COG2066	Belongs to the glutaminase family
MIT1002_RS13820	COG1785	Belongs to the alkaline phosphatase family
MIT1002_RS13825	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS13915	COG0438	transferase activity, transferring glycosyl groups
MIT1002_RS13930	COG0367	asparagine synthase
MIT1002_RS13935	COG0438	transferase activity, transferring glycosyl groups
MIT1002_RS13945	COG0463	Glycosyl transferase, family 2
MIT1002_RS13945	COG1216	Glycosyl transferase, family 2
MIT1002_RS13970	COG2244	polysaccharide biosynthetic process
MIT1002_RS14015	COG0489	protein tyrosine kinase activity
MIT1002_RS14025	COG3409	Peptidoglycan-binding domain 1 protein
MIT1002_RS14025	COG3267	Type II secretory pathway component ExeA
MIT1002_RS14030	COG2827	Endonuclease containing a URI domain
MIT1002_RS14050	COG1560	Kdo2-lipid A biosynthetic process
MIT1002_RS14065	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS14085	COG1435	thymidine kinase activity
MIT1002_RS14100	COG1609	Transcriptional regulator
MIT1002_RS14105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIT1002_RS14125	COG1082	Xylose isomerase domain protein TIM barrel
MIT1002_RS14130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIT1002_RS14135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_RS14150	COG1982	Orn Lys Arg decarboxylase major
MIT1002_RS14180	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS14200	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MIT1002_RS14205	COG0789	Transcriptional regulator
MIT1002_RS14235	COG1960	acyl-CoA dehydrogenase activity
MIT1002_RS14295	COG2080	2 iron, 2 sulfur cluster binding
MIT1002_RS14300	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MIT1002_RS14305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIT1002_RS14350	COG0601	transmembrane transport
MIT1002_RS14355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIT1002_RS14360	COG4172	Belongs to the ABC transporter superfamily
MIT1002_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS14375	COG0693	protein deglycase activity
MIT1002_RS14380	COG1295	ribonuclease BN
MIT1002_RS14390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MIT1002_RS14400	COG3279	Response regulator of the LytR AlgR family
MIT1002_RS14440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_RS14485	COG2814	Major facilitator Superfamily
MIT1002_RS14490	COG0339	signal peptide processing
MIT1002_RS14530	COG0514	ATP-dependent DNA helicase (RecQ)
MIT1002_RS14555	COG4251	negative regulation of phosphorylation
MIT1002_RS14560	COG2133	pyrroloquinoline quinone binding
MIT1002_RS14600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIT1002_RS14600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIT1002_RS14615	COG0738	Major facilitator superfamily
MIT1002_RS14620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIT1002_RS14630	COG2971	BadF BadG BcrA BcrD
MIT1002_RS14655	COG0583	DNA-binding transcription factor activity
MIT1002_RS14680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_RS14685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIT1002_RS14690	COG0006	proline dipeptidase activity
MIT1002_RS14705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_RS14720	COG2205	protein histidine kinase activity
MIT1002_RS14720	COG0784	Response regulator, receiver
MIT1002_RS14720	COG2198	Histidine kinase
MIT1002_RS14730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIT1002_RS14735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIT1002_RS14740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_RS14760	COG3313	Fe-S protein
MIT1002_RS14785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_RS14790	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_RS14795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MIT1002_RS14815	COG3577	Aspartyl protease
MIT1002_RS14820	COG0157	Belongs to the NadC ModD family
MIT1002_RS14825	COG4969	Belongs to the N-Me-Phe pilin family
MIT1002_RS14830	COG1459	type II secretion system
MIT1002_RS14835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MIT1002_RS14840	COG0237	dephospho-CoA kinase activity
MIT1002_RS14840	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIT1002_RS14845	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIT1002_RS14850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIT1002_RS14855	COG3608	succinylglutamate desuccinylase aspartoacylase
MIT1002_RS14860	COG0840	transmembrane signaling receptor activity
MIT1002_RS14865	COG4566	intracellular signal transduction
MIT1002_RS14880	COG2198	Histidine kinase
MIT1002_RS14880	COG0643	Histidine kinase
MIT1002_RS14890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MIT1002_RS14900	COG2201	protein-glutamate methylesterase activity
MIT1002_RS14905	COG0835	chemotaxis
MIT1002_RS14910	COG0840	transmembrane signaling receptor activity
MIT1002_RS14915	COG0494	nUDIX hydrolase
MIT1002_RS14925	COG0739	heme binding
MIT1002_RS14930	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MIT1002_RS14935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIT1002_RS14940	COG0849	cell division
MIT1002_RS14945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MIT1002_RS14950	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIT1002_RS14965	COG0772	Belongs to the SEDS family
MIT1002_RS14970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIT1002_RS14980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIT1002_RS14985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIT1002_RS14990	COG0768	penicillin binding
MIT1002_RS14995	COG3116	cell division
MIT1002_RS15005	COG2001	Belongs to the MraZ family
MIT1002_RS15025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS15030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS15050	COG0678	peroxiredoxin activity
MIT1002_RS15050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIT1002_RS15075	COG2204	response regulator
MIT1002_RS15100	COG0668	transmembrane transport
MIT1002_RS15105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIT1002_RS15110	COG0189	ligase activity
MIT1002_RS15115	COG1678	Uncharacterized ACR, COG1678
MIT1002_RS15120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIT1002_RS15145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIT1002_RS15150	COG0762	integral membrane protein
MIT1002_RS15160	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS15160	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIT1002_RS15190	COG1764	response to oxidative stress
MIT1002_RS15195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIT1002_RS15205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MIT1002_RS15210	COG1396	sequence-specific DNA binding
MIT1002_RS15215	COG2814	Major facilitator Superfamily
MIT1002_RS15220	COG0724	RNA recognition motif
MIT1002_RS15245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIT1002_RS15250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIT1002_RS15255	COG0083	homoserine kinase activity
MIT1002_RS15270	COG0583	DNA-binding transcription factor activity
MIT1002_RS15285	COG2197	response regulator
MIT1002_RS15290	COG4585	Histidine kinase
MIT1002_RS15305	COG0640	Transcriptional regulator
MIT1002_RS15315	COG0431	NADPH-dependent FMN reductase
MIT1002_RS15320	COG0798	PFAM Bile acid sodium symporter
MIT1002_RS15330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MIT1002_RS15340	COG0642	Histidine kinase
MIT1002_RS15360	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MIT1002_RS15370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIT1002_RS15395	COG1748	Saccharopine dehydrogenase
MIT1002_RS15415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIT1002_RS15420	COG3107	peptidoglycan biosynthetic process
MIT1002_RS15425	COG0792	nuclease activity
MIT1002_RS15440	COG2823	Periplasmic or secreted lipoprotein
MIT1002_RS15460	COG4585	Histidine kinase
MIT1002_RS15465	COG2197	response regulator
MIT1002_RS15480	COG4771	TonB-dependent receptor
MIT1002_RS15490	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MIT1002_RS15495	COG0372	Belongs to the citrate synthase family
MIT1002_RS15500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIT1002_RS15505	COG2828	Protein conserved in bacteria
MIT1002_RS15510	COG2199	diguanylate cyclase activity
MIT1002_RS15510	COG2203	Gaf domain
MIT1002_RS15530	COG0784	Response regulator, receiver
MIT1002_RS15530	COG2198	Histidine kinase
MIT1002_RS15530	COG5002	protein histidine kinase activity
MIT1002_RS15540	COG0067	glutamate synthase
MIT1002_RS15540	COG0069	glutamate synthase activity
MIT1002_RS15540	COG0070	glutamate synthase
MIT1002_RS15545	COG0493	'glutamate synthase
MIT1002_RS15565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIT1002_RS15570	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MIT1002_RS15575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIT1002_RS15580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIT1002_RS15595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIT1002_RS15600	COG5507	3-demethylubiquinone-9 3-methyltransferase
MIT1002_RS15620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIT1002_RS15625	COG1196	nuclear chromosome segregation
MIT1002_RS15625	COG0741	lytic transglycosylase activity
MIT1002_RS15625	COG0739	heme binding
MIT1002_RS15630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MIT1002_RS15640	COG0738	Major facilitator superfamily
MIT1002_RS15650	COG1902	pentaerythritol trinitrate reductase activity
MIT1002_RS15665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIT1002_RS15670	COG0625	glutathione transferase activity
MIT1002_RS15690	COG2894	cell division
MIT1002_RS15695	COG0850	regulation of cytokinetic process
MIT1002_RS15730	COG1981	membrane
MIT1002_RS15745	COG1914	H( )-stimulated, divalent metal cation uptake system
MIT1002_RS15750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MIT1002_RS15755	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS15760	COG1217	gtp-binding protein TYPA
MIT1002_RS15765	COG0174	glutamine synthetase
MIT1002_RS15775	COG3852	Histidine kinase
MIT1002_RS15780	COG2204	response regulator
MIT1002_RS15785	COG3437	response regulator, receiver
MIT1002_RS15830	COG0525	valine-tRNA ligase activity
MIT1002_RS15835	COG2927	DNA polymerase III (CHI subunit)
MIT1002_RS15840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIT1002_RS15845	COG0795	lipopolysaccharide-transporting ATPase activity
MIT1002_RS15850	COG0795	lipopolysaccharide-transporting ATPase activity
MIT1002_RS15925	COG1733	regulation of RNA biosynthetic process
MIT1002_RS15940	COG0625	glutathione transferase activity
MIT1002_RS15955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIT1002_RS15960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_RS15965	COG1017	nitric oxide dioxygenase activity
MIT1002_RS15965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIT1002_RS15970	COG3604	Transcriptional regulator
MIT1002_RS16000	COG0673	inositol 2-dehydrogenase activity
MIT1002_RS16010	COG0628	permease
MIT1002_RS16040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIT1002_RS16050	COG0642	Histidine kinase
MIT1002_RS16100	COG1971	Probably functions as a manganese efflux pump
MIT1002_RS16125	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MIT1002_RS16130	COG3706	GGDEF domain
MIT1002_RS16135	COG0679	Auxin Efflux Carrier
MIT1002_RS16140	COG2267	carboxylic ester hydrolase activity
MIT1002_RS16170	COG1131	(ABC) transporter
MIT1002_RS16180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIT1002_RS16235	COG2205	protein histidine kinase activity
MIT1002_RS16245	COG0348	domain, Protein
MIT1002_RS16245	COG3901	Regulator of nitric oxide reductase transcription
MIT1002_RS16255	COG2197	response regulator
MIT1002_RS16295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIT1002_RS16300	COG0583	DNA-binding transcription factor activity
MIT1002_RS16305	COG1304	FMN binding
MIT1002_RS16310	COG0277	FAD linked oxidase domain protein
MIT1002_RS16320	COG1462	curli production assembly transport component CsgG
MIT1002_RS16350	COG2197	response regulator
MIT1002_RS16365	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS16370	COG3264	Mechanosensitive ion channel
MIT1002_RS16370	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MIT1002_RS16390	COG2202	Pas domain
MIT1002_RS16390	COG2200	EAL domain
MIT1002_RS16390	COG2199	diguanylate cyclase activity
MIT1002_RS16415	COG0730	response to heat
MIT1002_RS16420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIT1002_RS16435	COG4191	Histidine kinase
MIT1002_RS16445	COG0417	DNA replication proofreading
MIT1002_RS16455	COG0318	PFAM AMP-dependent synthetase and ligase
MIT1002_RS16510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_RS16520	COG1573	uracil-dna glycosylase
MIT1002_RS16525	COG3300	MHYT domain
MIT1002_RS16525	COG5001	Diguanylate cyclase
MIT1002_RS16545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIT1002_RS16565	COG1983	PspC domain protein
MIT1002_RS16570	COG1842	Phage shock protein A
MIT1002_RS16580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_RS16595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIT1002_RS16605	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIT1002_RS16610	COG0204	Acyl-transferase
MIT1002_RS16615	COG0204	Acyl-transferase
MIT1002_RS16620	COG0668	transmembrane transport
MIT1002_RS16635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIT1002_RS16640	COG0733	neurotransmitter:sodium symporter activity
MIT1002_RS16655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIT1002_RS16670	COG0716	FMN binding
MIT1002_RS16680	COG0848	biopolymer transport protein
MIT1002_RS16690	COG0457	Tetratricopeptide repeat
MIT1002_RS16695	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MIT1002_RS16720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MIT1002_RS16725	COG0702	epimerase
MIT1002_RS16740	COG5001	Diguanylate cyclase
MIT1002_RS16740	COG5002	protein histidine kinase activity
MIT1002_RS16750	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MIT1002_RS16760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_RS16770	COG0583	DNA-binding transcription factor activity
MIT1002_RS16775	COG0121	glutamine amidotransferase
MIT1002_RS16790	COG4682	membrane
MIT1002_RS16810	COG1953	Uracil, thiamine, allantoin
MIT1002_RS16815	COG4771	TonB-dependent receptor
MIT1002_RS16825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIT1002_RS16830	COG0778	Nitroreductase
MIT1002_RS16835	COG0596	Alpha beta hydrolase
MIT1002_RS16840	COG0251	oxidation-reduction process
MIT1002_RS16845	COG1335	isochorismatase
MIT1002_RS16850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_RS16855	COG1309	transcriptional regulator
MIT1002_RS16870	COG4628	conserved protein (DUF2132)
MIT1002_RS16875	COG2610	gluconate transmembrane transporter activity
MIT1002_RS16880	COG3265	gluconokinase activity
MIT1002_RS16885	COG1609	Transcriptional regulator
MIT1002_RS16890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIT1002_RS16900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIT1002_RS16920	COG1477	protein flavinylation
MIT1002_RS16925	COG2871	sodium ion transport
MIT1002_RS16930	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_RS16935	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_RS16940	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_RS16945	COG1805	sodium ion transport
MIT1002_RS16950	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MIT1002_RS16955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MIT1002_RS16960	COG0545	Peptidyl-prolyl cis-trans isomerase
MIT1002_RS16965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIT1002_RS16970	COG0039	L-malate dehydrogenase activity
MIT1002_RS16975	COG1438	arginine binding
MIT1002_RS17000	COG0572	uridine kinase
MIT1002_RS17005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIT1002_RS17020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MIT1002_RS17045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_RS17065	COG0189	ligase activity
MIT1002_RS17075	COG0189	ligase activity
MIT1002_RS17075	COG4067	protein conserved in archaea
MIT1002_RS17090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIT1002_RS17100	COG1283	sodium-dependent phosphate transmembrane transporter activity
MIT1002_RS17105	COG0667	Aldo Keto reductase
MIT1002_RS17160	COG0753	catalase activity
MIT1002_RS17200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIT1002_RS17210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MIT1002_RS17260	COG0583	DNA-binding transcription factor activity
MIT1002_RS17295	COG0438	transferase activity, transferring glycosyl groups
MIT1002_RS17295	COG1216	Glycosyl transferase, family 2
MIT1002_RS17315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIT1002_RS17360	COG1028	Short-chain dehydrogenase reductase Sdr
MIT1002_RS17370	COG1083	cytidylyl-transferase
MIT1002_RS17410	COG0438	transferase activity, transferring glycosyl groups
MIT1002_RS17410	COG0297	glycogen (starch) synthase activity
MIT1002_RS17420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIT1002_RS17425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIT1002_RS17450	COG0202	RNA polymerase activity
MIT1002_RS17475	COG0201	protein transport
MIT1002_RS17495	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIT1002_RS17530	COG5002	protein histidine kinase activity
MIT1002_RS17530	COG0784	Response regulator, receiver
MIT1002_RS17545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIT1002_RS17550	COG0557	exoribonuclease II activity
MIT1002_RS17570	COG4771	TonB-dependent receptor
MIT1002_RS17585	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MIT1002_RS17605	COG2234	aminopeptidase activity
MIT1002_RS17615	COG4251	negative regulation of phosphorylation
MIT1002_RS17625	COG1271	oxidase subunit
MIT1002_RS17630	COG1294	oxidase, subunit
MIT1002_RS17645	COG1522	sequence-specific DNA binding
MIT1002_RS17655	COG1278	Cold shock
MIT1002_RS17660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIT1002_RS17670	COG2226	methyltransferase
MIT1002_RS17680	COG0339	signal peptide processing
MIT1002_RS17685	COG2201	protein-glutamate methylesterase activity
MIT1002_RS17705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIT1002_RS17710	COG0243	molybdopterin cofactor binding
MIT1002_RS17725	COG4946	Tricorn protease homolog
MIT1002_RS17725	COG1506	peptidase
MIT1002_RS17725	COG0823	Involved in the tonB-independent uptake of proteins
MIT1002_RS17770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIT1002_RS17780	COG2197	response regulator
MIT1002_RS17810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIT1002_RS17815	COG1278	Cold shock
MIT1002_RS17825	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MIT1002_RS17830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIT1002_RS17845	COG0281	malic enzyme
MIT1002_RS17855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIT1002_RS17885	COG0456	acetyltransferase
MIT1002_RS17895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MIT1002_RS17900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MIT1002_RS17905	COG2177	Part of the ABC transporter FtsEX involved in
MIT1002_RS17910	COG2884	Cell division ATP-binding protein ftsE
MIT1002_RS17915	COG0552	protein localization to endoplasmic reticulum
MIT1002_RS17920	COG0742	ribosomal rna small subunit methyltransferase
MIT1002_RS17930	COG2095	MarC family integral membrane protein
MIT1002_RS17950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MIT1002_RS17955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIT1002_RS17960	COG0617	tRNA 3'-terminal CCA addition
MIT1002_RS17965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIT1002_RS17980	COG0076	glutamate decarboxylase activity
MIT1002_RS17995	COG0842	Transport permease protein
MIT1002_RS18000	COG1131	(ABC) transporter
MIT1002_RS18005	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS18010	COG2205	protein histidine kinase activity
MIT1002_RS18030	COG1253	flavin adenine dinucleotide binding
MIT1002_RS18035	COG0701	Predicted permease
MIT1002_RS18040	COG1966	Carbon starvation protein
MIT1002_RS18090	COG0848	biopolymer transport protein
MIT1002_RS18100	COG0811	peptide transport
MIT1002_RS18120	COG3128	pkhd-type hydroxylase
MIT1002_RS18145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIT1002_RS18150	COG0049	tRNA binding
MIT1002_RS18155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIT1002_RS18160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIT1002_RS18165	COG0085	RNA polymerase activity
MIT1002_RS18170	COG0222	ribosome binding
MIT1002_RS18175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIT1002_RS18180	COG0081	regulation of translation
MIT1002_RS18185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIT1002_RS18195	COG0250	Participates in transcription elongation, termination and antitermination
MIT1002_RS18200	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIT1002_RS18210	COG1132	(ABC) transporter
MIT1002_RS18215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIT1002_RS18220	COG3590	peptidase
MIT1002_RS18235	COG0513	Belongs to the DEAD box helicase family
MIT1002_RS18245	COG0418	dihydroorotase activity
MIT1002_RS18250	COG3040	lipid binding
MIT1002_RS18255	COG4989	oxidoreductase activity
MIT1002_RS18260	COG0346	lactoylglutathione lyase activity
MIT1002_RS18265	COG0668	transmembrane transport
MIT1002_RS18285	COG0302	gtp cyclohydrolase
MIT1002_RS18295	COG2957	Belongs to the agmatine deiminase family
MIT1002_RS18310	COG1201	RNA secondary structure unwinding
MIT1002_RS18315	COG2311	Membrane
MIT1002_RS18330	COG1793	dna ligase
MIT1002_RS18335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIT1002_RS18340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIT1002_RS18365	COG0625	glutathione transferase activity
MIT1002_RS18370	COG0625	glutathione transferase activity
MIT1002_RS18380	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIT1002_RS18395	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS18400	COG0028	Belongs to the TPP enzyme family
MIT1002_RS18410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MIT1002_RS18415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MIT1002_RS18420	COG0330	HflC and HflK could
MIT1002_RS18425	COG0330	HflC and HflK could
MIT1002_RS18430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIT1002_RS18435	COG1923	regulation of RNA biosynthetic process
MIT1002_RS18440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIT1002_RS18455	COG0802	atpase or kinase
MIT1002_RS18460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIT1002_RS18460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MIT1002_RS18465	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIT1002_RS18485	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MIT1002_RS18490	COG0735	belongs to the Fur family
MIT1002_RS18510	COG0305	Participates in initiation and elongation during chromosome replication
MIT1002_RS18535	COG2258	MOSC domain
MIT1002_RS18605	COG0840	transmembrane signaling receptor activity
MIT1002_RS18610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIT1002_RS18610	COG4191	Histidine kinase
MIT1002_RS18615	COG0840	transmembrane signaling receptor activity
MIT1002_RS18630	COG2855	membrane
MIT1002_RS18635	COG2175	clavaminate synthase activity
MIT1002_RS18640	COG0656	L-ascorbic acid biosynthetic process
MIT1002_RS18660	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIT1002_RS18665	COG4771	TonB-dependent receptor
MIT1002_RS18685	COG3706	GGDEF domain
MIT1002_RS18690	COG1757	Na H antiporter
MIT1002_RS18695	COG1472	Belongs to the glycosyl hydrolase 3 family
MIT1002_RS18705	COG2723	6-phospho-beta-galactosidase activity
MIT1002_RS18710	COG1609	Transcriptional regulator
MIT1002_RS18715	COG0477	Major facilitator Superfamily
MIT1002_RS18715	COG2814	Major facilitator Superfamily
MIT1002_RS18720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MIT1002_RS18725	COG4988	ABC transporter
MIT1002_RS18730	COG4890	Cyd operon protein YbgT
MIT1002_RS18735	COG1294	oxidase, subunit
MIT1002_RS18775	COG4319	ketosteroid isomerase
MIT1002_RS18780	COG1335	isochorismatase
MIT1002_RS18785	COG2863	cytochrome
MIT1002_RS18805	COG1741	Belongs to the pirin family
MIT1002_RS18820	COG4771	TonB-dependent receptor
MIT1002_RS18835	COG1469	GTP cyclohydrolase I activity
MIT1002_RS18890	COG3237	CsbD-like
MIT1002_RS18905	COG1595	DNA-templated transcription, initiation
MIT1002_RS18935	COG0596	Alpha beta hydrolase
MIT1002_RS18935	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIT1002_RS18960	COG3038	cytochrome b561
MIT1002_RS18970	COG1252	NADH dehydrogenase
MIT1002_RS18975	COG4206	TonB-dependent receptor
MIT1002_RS18990	COG0583	DNA-binding transcription factor activity
MIT1002_RS18995	COG2067	long-chain fatty acid transport protein
MIT1002_RS19000	COG2130	NADP-dependent
MIT1002_RS19005	COG2203	Gaf domain
MIT1002_RS19005	COG3706	GGDEF domain
MIT1002_RS19005	COG4251	negative regulation of phosphorylation
MIT1002_RS19005	COG5001	Diguanylate cyclase
MIT1002_RS19010	COG0784	Response regulator, receiver
MIT1002_RS19010	COG2205	protein histidine kinase activity
MIT1002_RS19020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIT1002_RS19025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MIT1002_RS19030	COG1349	DNA-binding transcription factor activity
MIT1002_RS19035	COG0673	inositol 2-dehydrogenase activity
MIT1002_RS19050	COG0697	spore germination
MIT1002_RS19055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIT1002_RS19060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIT1002_RS19065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MIT1002_RS19070	COG1166	arginine decarboxylase activity
MIT1002_RS19080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIT1002_RS19160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIT1002_RS19170	COG0109	protoheme IX farnesyltransferase activity
MIT1002_RS19190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIT1002_RS19235	COG1324	tolerance protein
MIT1002_RS19240	COG4232	protein-disulfide reductase activity
MIT1002_RS19245	COG0739	heme binding
MIT1002_RS19250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIT1002_RS19255	COG0511	ligase activity, forming carbon-carbon bonds
MIT1002_RS19260	COG0439	Biotin carboxylase
MIT1002_RS19305	COG0154	amidase activity
MIT1002_RS19320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIT1002_RS19325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MIT1002_RS19340	COG0151	Belongs to the GarS family
MIT1002_RS19355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIT1002_RS19360	COG3954	Phosphoribulokinase
MIT1002_RS19385	COG1501	Belongs to the glycosyl hydrolase 31 family
MIT1002_RS19390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MIT1002_RS19395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIT1002_RS19405	COG3031	protein transport across the cell outer membrane
MIT1002_RS19415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIT1002_RS19420	COG1459	type II secretion system
MIT1002_RS19425	COG2165	general secretion pathway protein
MIT1002_RS19430	COG2165	general secretion pathway protein
MIT1002_RS19435	COG2165	general secretion pathway protein
MIT1002_RS19440	COG4795	General secretion pathway protein
MIT1002_RS19455	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MIT1002_RS19475	COG1012	belongs to the aldehyde dehydrogenase family
MIT1002_RS19485	COG1011	Hydrolase
MIT1002_RS19490	COG0494	nUDIX hydrolase
MIT1002_RS19495	COG1218	3'(2'),5'-bisphosphate nucleotidase
MIT1002_RS19505	COG2943	transferase activity, transferring hexosyl groups
MIT1002_RS19510	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MIT1002_RS19520	COG3089	Belongs to the UPF0270 family
MIT1002_RS19525	COG0429	hydrolase of the alpha beta-hydrolase fold
MIT1002_RS19535	COG0488	(ABC) transporter
MIT1002_RS19565	COG0545	Peptidyl-prolyl cis-trans isomerase
MIT1002_RS19575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIT1002_RS19580	COG2183	response to ionizing radiation
MIT1002_RS19605	COG1609	Transcriptional regulator
MIT1002_RS19605	COG2207	Transcriptional regulator
MIT1002_RS19610	COG2211	Major facilitator Superfamily
MIT1002_RS19635	COG3693	PFAM glycoside hydrolase, family 10
MIT1002_RS19640	COG0667	Aldo Keto reductase
MIT1002_RS19645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIT1002_RS19650	COG2115	Belongs to the xylose isomerase family
MIT1002_RS19655	COG1070	Carbohydrate kinase
MIT1002_RS19670	COG1472	Belongs to the glycosyl hydrolase 3 family
MIT1002_RS19675	COG0477	Major facilitator Superfamily
MIT1002_RS19715	COG0596	Alpha beta hydrolase
MIT1002_RS19720	COG1040	competence protein
MIT1002_RS19740	COG1794	racemase activity, acting on amino acids and derivatives
MIT1002_RS19755	COG0534	Mate efflux family protein
MIT1002_RS19770	COG1999	signal sequence binding
MIT1002_RS19775	COG0109	protoheme IX farnesyltransferase activity
MIT1002_RS19780	COG1612	heme a metabolic process
MIT1002_RS19805	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MIT1002_RS19810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIT1002_RS19815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIT1002_RS19830	COG3706	GGDEF domain
MIT1002_RS19845	COG0129	dihydroxy-acid dehydratase activity
MIT1002_RS19850	COG2860	membrane
MIT1002_RS19855	COG0606	chelatase, subunit chli
MIT1002_RS19860	COG0583	DNA-binding transcription factor activity
MIT1002_RS19870	COG2814	Major facilitator Superfamily
MIT1002_RS19880	COG0729	surface antigen
MIT1002_RS19885	COG2911	Protein conserved in bacteria
MIT1002_RS19910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIT1002_RS19920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIT1002_RS19940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIT1002_RS19965	COG1228	amidohydrolase
MIT1002_RS19985	COG0425	Belongs to the sulfur carrier protein TusA family
MIT1002_RS20000	COG1561	YicC-like family, N-terminal region
MIT1002_RS20025	COG2211	Major facilitator Superfamily
MIT1002_RS20030	COG1609	Transcriptional regulator
MIT1002_RS20050	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MIT1002_RS20050	COG2199	diguanylate cyclase activity
MIT1002_RS20075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MIT1002_RS20095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIT1002_RS20100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIT1002_RS20120	COG1475	DNA binding
MIT1002_RS20125	COG1192	Involved in chromosome partitioning
MIT1002_RS20150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIT1002_RS20155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIT1002_RS20165	COG0706	membrane insertase activity
MIT1002_RS20170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MIT1002_RS20175	COG0594	ribonuclease P activity
MIT1002_RS20180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MIT1002_RS20205	COG2207	Transcriptional regulator
MIT1002_RS20205	COG1917	Cupin 2, conserved barrel domain protein
MIT1002_RS20210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MIT1002_RS20215	COG1280	lysine exporter protein (LysE YggA)
MIT1002_RS20220	COG1522	sequence-specific DNA binding
MIT1002_RS20270	COG1396	sequence-specific DNA binding
MIT1002_RS20275	COG3550	peptidyl-serine autophosphorylation
MIT1002_RS20355	COG1192	Involved in chromosome partitioning
MIT1002_RS20400	COG5002	protein histidine kinase activity
MIT1002_RS20405	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS20425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIT1002_RS20505	COG1017	nitric oxide dioxygenase activity
MIT1002_RS20505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIT1002_RS20525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MIT1002_RS20555	COG0375	protein maturation
MIT1002_RS20565	COG0409	Hydrogenase expression formation protein
MIT1002_RS20575	COG0309	Hydrogenase expression formation protein (HypE)
MIT1002_RS20580	COG0789	Transcriptional regulator
MIT1002_RS20585	COG2217	Heavy metal translocating P-type atpase
MIT1002_RS20675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MIT1002_RS20685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIT1002_RS20695	COG0463	Glycosyl transferase, family 2
MIT1002_RS20700	COG0745	RESPONSE REGULATOR receiver
MIT1002_RS20705	COG5002	protein histidine kinase activity
MIT1002_RS20740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIT1002_RS20745	COG0789	Transcriptional regulator
MIT1002_RS20750	COG2217	Heavy metal translocating P-type atpase
MIT1002_RS20790	COG0531	amino acid
MIT1002_RS20820	COG3209	COG3209 Rhs family protein
MIT1002_RS20830	COG0789	Transcriptional regulator