locus-tag	class	description
AVL55_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVL55_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVL55_RS00040	COG2818	Glycosylase
AVL55_RS00050	COG3078	GTPase activator activity
AVL55_RS00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL55_RS00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL55_RS00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVL55_RS00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVL55_RS00085	COG0569	domain protein
AVL55_RS00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVL55_RS00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVL55_RS00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVL55_RS00110	COG0758	DNA mediated transformation
AVL55_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
AVL55_RS00130	COG0408	coproporphyrinogen oxidase activity
AVL55_RS00135	COG3047	cAMP biosynthetic process
AVL55_RS00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVL55_RS00230	COG2234	aminopeptidase activity
AVL55_RS00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVL55_RS00265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL55_RS00295	COG3642	lipopolysaccharide core region biosynthetic process
AVL55_RS00325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL55_RS00340	COG3161	chorismate lyase activity
AVL55_RS00345	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVL55_RS00355	COG0210	DNA helicase
AVL55_RS00385	COG1757	Na H antiporter
AVL55_RS00390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVL55_RS00475	COG0583	DNA-binding transcription factor activity
AVL55_RS00485	COG3106	COG3106 Predicted ATPase
AVL55_RS00500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVL55_RS00515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL55_RS00520	COG0352	thiamine-phosphate diphosphorylase activity
AVL55_RS00530	COG3071	HemY protein
AVL55_RS00535	COG2959	enzyme of heme biosynthesis
AVL55_RS00545	COG0181	hydroxymethylbilane synthase activity
AVL55_RS00560	COG0194	GDP metabolic process
AVL55_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL55_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL55_RS00585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVL55_RS00595	COG0678	peroxiredoxin activity
AVL55_RS00610	COG1178	ABC-type Fe3 transport system permease component
AVL55_RS00615	COG3842	ATPase activity
AVL55_RS00620	COG2081	HI0933 family
AVL55_RS00660	COG0789	Transcriptional regulator
AVL55_RS00675	COG3047	cAMP biosynthetic process
AVL55_RS00710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS00725	COG0427	acetyl-CoA hydrolase
AVL55_RS00730	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL55_RS00745	COG0840	transmembrane signaling receptor activity
AVL55_RS00755	COG3064	Membrane
AVL55_RS00765	COG5002	protein histidine kinase activity
AVL55_RS00765	COG5001	Diguanylate cyclase
AVL55_RS00780	COG0514	ATP-dependent DNA helicase (RecQ)
AVL55_RS00785	COG2050	protein possibly involved in aromatic compounds catabolism
AVL55_RS00790	COG2239	Acts as a magnesium transporter
AVL55_RS00795	COG2962	Rard protein
AVL55_RS00800	COG3706	GGDEF domain
AVL55_RS00805	COG0210	DNA helicase
AVL55_RS00815	COG3706	GGDEF domain
AVL55_RS00820	COG1011	Hydrolase
AVL55_RS00825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVL55_RS00835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVL55_RS00840	COG0019	diaminopimelate decarboxylase activity
AVL55_RS00870	COG0163	prenyltransferase activity
AVL55_RS00875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL55_RS00885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVL55_RS00910	COG1077	Cell shape determining protein MreB Mrl
AVL55_RS00915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVL55_RS00920	COG2814	Major facilitator Superfamily
AVL55_RS00945	COG1085	galactose-1-phosphate uridylyltransferase
AVL55_RS00950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVL55_RS00960	COG0629	single-stranded DNA binding
AVL55_RS01005	COG1858	cytochrome C peroxidase
AVL55_RS01025	COG3250	beta-galactosidase activity
AVL55_RS01040	COG1349	DNA-binding transcription factor activity
AVL55_RS01065	COG1077	Cell shape determining protein MreB Mrl
AVL55_RS01070	COG1792	Involved in formation and maintenance of cell shape
AVL55_RS01075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AVL55_RS01085	COG1530	ribonuclease E activity
AVL55_RS01095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL55_RS01100	COG0312	modulator of DNA gyrase
AVL55_RS01110	COG3028	Belongs to the UPF0307 family
AVL55_RS01115	COG0312	modulator of DNA gyrase
AVL55_RS01130	COG0745	RESPONSE REGULATOR receiver
AVL55_RS01135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL55_RS01135	COG4191	Histidine kinase
AVL55_RS01140	COG0297	glycogen (starch) synthase activity
AVL55_RS01150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVL55_RS01195	COG2201	protein-glutamate methylesterase activity
AVL55_RS01230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AVL55_RS01240	COG0789	Transcriptional regulator
AVL55_RS01245	COG2217	Heavy metal translocating P-type atpase
AVL55_RS01315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL55_RS01325	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVL55_RS01335	COG0463	Glycosyl transferase, family 2
AVL55_RS01340	COG0745	RESPONSE REGULATOR receiver
AVL55_RS01345	COG5002	protein histidine kinase activity
AVL55_RS01375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVL55_RS01385	COG0789	Transcriptional regulator
AVL55_RS01390	COG2217	Heavy metal translocating P-type atpase
AVL55_RS01425	COG0531	amino acid
AVL55_RS01435	COG2132	Multicopper oxidase
AVL55_RS01460	COG0546	phosphoglycolate phosphatase activity
AVL55_RS01465	COG0784	Response regulator, receiver
AVL55_RS01465	COG2205	protein histidine kinase activity
AVL55_RS01480	COG1609	Transcriptional regulator
AVL55_RS01485	COG0673	inositol 2-dehydrogenase activity
AVL55_RS01495	COG2211	Major facilitator Superfamily
AVL55_RS01520	COG1454	alcohol dehydrogenase
AVL55_RS01580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL55_RS01600	COG0089	rRNA binding
AVL55_RS01610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVL55_RS01620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVL55_RS01635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVL55_RS01645	COG1519	Transferase
AVL55_RS01690	COG0788	formyltetrahydrofolate deformylase activity
AVL55_RS01700	COG1643	Atp-dependent helicase
AVL55_RS01710	COG2951	lytic endotransglycosylase activity
AVL55_RS01715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVL55_RS01725	COG2354	Protein conserved in bacteria
AVL55_RS01745	COG0004	ammonium transporteR
AVL55_RS01765	COG0753	catalase activity
AVL55_RS01775	COG0667	Aldo Keto reductase
AVL55_RS01780	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVL55_RS01785	COG0405	Gamma-glutamyltransferase
AVL55_RS01790	COG2837	iron assimilation
AVL55_RS01800	COG0540	Belongs to the ATCase OTCase family
AVL55_RS01825	COG2205	protein histidine kinase activity
AVL55_RS01825	COG5002	protein histidine kinase activity
AVL55_RS01825	COG0784	Response regulator, receiver
AVL55_RS01840	COG3300	MHYT domain
AVL55_RS01840	COG5001	Diguanylate cyclase
AVL55_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
AVL55_RS01860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVL55_RS01870	COG0512	Glutamine amidotransferase of anthranilate synthase
AVL55_RS01875	COG0180	Tryptophanyl-tRNA synthetase
AVL55_RS01880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVL55_RS01900	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AVL55_RS01910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVL55_RS01945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVL55_RS01950	COG0281	malic enzyme
AVL55_RS01960	COG0625	glutathione transferase activity
AVL55_RS01970	COG0753	catalase activity
AVL55_RS01985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AVL55_RS01985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVL55_RS01995	COG0137	argininosuccinate synthase activity
AVL55_RS02015	COG1803	Methylglyoxal synthase
AVL55_RS02025	COG0745	RESPONSE REGULATOR receiver
AVL55_RS02030	COG2205	protein histidine kinase activity
AVL55_RS02035	COG2267	carboxylic ester hydrolase activity
AVL55_RS02040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVL55_RS02050	COG1136	(ABC) transporter
AVL55_RS02050	COG0577	efflux transmembrane transporter activity
AVL55_RS02060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVL55_RS02070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL55_RS02075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL55_RS02080	COG4942	peptidase
AVL55_RS02085	COG2861	carbohydrate metabolic process
AVL55_RS02095	COG0584	glycerophosphoryl diester phosphodiesterase
AVL55_RS02110	COG1162	GTPase activity
AVL55_RS02115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AVL55_RS02150	COG0028	Belongs to the TPP enzyme family
AVL55_RS02170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVL55_RS02175	COG0805	protein transport
AVL55_RS02185	COG0084	hydrolase, TatD family'
AVL55_RS02190	COG3706	GGDEF domain
AVL55_RS02190	COG2203	Gaf domain
AVL55_RS02190	COG5001	Diguanylate cyclase
AVL55_RS02190	COG4251	negative regulation of phosphorylation
AVL55_RS02200	COG0248	Ppx GppA phosphatase
AVL55_RS02205	COG0513	Belongs to the DEAD box helicase family
AVL55_RS02210	COG3118	belongs to the thioredoxin family
AVL55_RS02215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVL55_RS02220	COG1473	amidohydrolase
AVL55_RS02225	COG2205	protein histidine kinase activity
AVL55_RS02225	COG0784	Response regulator, receiver
AVL55_RS02230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVL55_RS02235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVL55_RS02240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVL55_RS02255	COG0783	Belongs to the Dps family
AVL55_RS02260	COG2133	pyrroloquinoline quinone binding
AVL55_RS02265	COG0823	Involved in the tonB-independent uptake of proteins
AVL55_RS02265	COG1506	peptidase
AVL55_RS02265	COG4946	Tricorn protease homolog
AVL55_RS02275	COG3118	belongs to the thioredoxin family
AVL55_RS02290	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AVL55_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
AVL55_RS02320	COG1757	Na H antiporter
AVL55_RS02335	COG3876	Protein conserved in bacteria
AVL55_RS02340	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AVL55_RS02360	COG0346	lactoylglutathione lyase activity
AVL55_RS02395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVL55_RS02405	COG2824	Alkylphosphonate utilization operon protein PhnA
AVL55_RS02410	COG0454	-acetyltransferase
AVL55_RS02420	COG1742	UPF0060 membrane protein
AVL55_RS02440	COG3344	reverse transcriptase
AVL55_RS02445	COG3093	addiction module antidote protein HigA
AVL55_RS02450	COG4115	mRNA cleavage
AVL55_RS02455	COG2161	toxin-antitoxin pair type II binding
AVL55_RS02485	COG3547	Transposase (IS116 IS110 IS902 family)
AVL55_RS02520	COG0183	Belongs to the thiolase family
AVL55_RS02525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL55_RS02525	COG1024	Enoyl-CoA hydratase
AVL55_RS02535	COG0006	proline dipeptidase activity
AVL55_RS02545	COG0142	geranyltranstransferase activity
AVL55_RS02595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVL55_RS02600	COG1388	LysM domain
AVL55_RS02600	COG4942	peptidase
AVL55_RS02605	COG1238	metal cluster binding
AVL55_RS02615	COG0585	pseudouridine synthase activity
AVL55_RS02620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVL55_RS02630	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVL55_RS02640	COG0840	transmembrane signaling receptor activity
AVL55_RS02645	COG1522	sequence-specific DNA binding
AVL55_RS02660	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL55_RS02660	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL55_RS02660	COG0506	proline dehydrogenase activity
AVL55_RS02675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS02710	COG0494	nUDIX hydrolase
AVL55_RS02715	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AVL55_RS02720	COG0730	response to heat
AVL55_RS02725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVL55_RS02730	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVL55_RS02740	COG3706	GGDEF domain
AVL55_RS02745	COG2205	protein histidine kinase activity
AVL55_RS02745	COG4999	Histidine kinase
AVL55_RS02745	COG3850	Histidine kinase
AVL55_RS02745	COG3437	response regulator, receiver
AVL55_RS02750	COG2211	Major facilitator Superfamily
AVL55_RS02770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVL55_RS02780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVL55_RS02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVL55_RS02805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL55_RS02805	COG1648	precorrin-2 dehydrogenase activity
AVL55_RS02810	COG0513	Belongs to the DEAD box helicase family
AVL55_RS02825	COG1538	Outer membrane efflux protein
AVL55_RS02830	COG0494	nUDIX hydrolase
AVL55_RS02840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVL55_RS02845	COG3150	esterase
AVL55_RS02860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL55_RS02880	COG1509	lysine 2,3-aminomutase activity
AVL55_RS02885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVL55_RS02910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL55_RS02925	COG0271	Belongs to the BolA IbaG family
AVL55_RS02940	COG3707	response regulator
AVL55_RS02950	COG0659	secondary active sulfate transmembrane transporter activity
AVL55_RS02955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVL55_RS02960	COG2146	nitrite reductase [NAD(P)H] activity
AVL55_RS02965	COG0243	molybdopterin cofactor binding
AVL55_RS02970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL55_RS02970	COG1648	precorrin-2 dehydrogenase activity
AVL55_RS02980	COG0737	Belongs to the 5'-nucleotidase family
AVL55_RS02985	COG4251	negative regulation of phosphorylation
AVL55_RS02985	COG5001	Diguanylate cyclase
AVL55_RS02985	COG2203	Gaf domain
AVL55_RS02985	COG3706	GGDEF domain
AVL55_RS02995	COG1116	anion transmembrane transporter activity
AVL55_RS02995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVL55_RS03005	COG1116	anion transmembrane transporter activity
AVL55_RS03020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL55_RS03025	COG4206	TonB-dependent receptor
AVL55_RS03030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVL55_RS03035	COG0348	domain, Protein
AVL55_RS03050	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS03065	COG4948	Mandelate Racemase Muconate Lactonizing
AVL55_RS03080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS03085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS03105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVL55_RS03110	COG0358	DNA primase activity
AVL55_RS03135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVL55_RS03140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL55_RS03155	COG0537	adenosine 5'-monophosphoramidase activity
AVL55_RS03170	COG3135	benzoate transporter
AVL55_RS03175	COG1396	sequence-specific DNA binding
AVL55_RS03180	COG2974	May be involved in recombination
AVL55_RS03185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL55_RS03185	COG4191	Histidine kinase
AVL55_RS03190	COG0745	RESPONSE REGULATOR receiver
AVL55_RS03195	COG5002	protein histidine kinase activity
AVL55_RS03225	COG0811	peptide transport
AVL55_RS03230	COG0811	peptide transport
AVL55_RS03235	COG0848	biopolymer transport protein
AVL55_RS03240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AVL55_RS03260	COG2133	pyrroloquinoline quinone binding
AVL55_RS03265	COG1049	propionate catabolic process, 2-methylcitrate cycle
AVL55_RS03300	COG0527	aspartate kinase activity
AVL55_RS03315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVL55_RS03320	COG2967	ApaG domain
AVL55_RS03330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVL55_RS03335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL55_RS03340	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVL55_RS03350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVL55_RS03360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL55_RS03365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVL55_RS03380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVL55_RS03395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL55_RS03400	COG3956	TIGRFAM MazG family protein
AVL55_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
AVL55_RS03445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVL55_RS03455	COG0463	Glycosyl transferase, family 2
AVL55_RS03495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVL55_RS03500	COG0723	plastoquinol--plastocyanin reductase activity
AVL55_RS03505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVL55_RS03510	COG2857	Cytochrome c1
AVL55_RS03515	COG0625	glutathione transferase activity
AVL55_RS03520	COG2969	positive regulation of protein catabolic process
AVL55_RS03525	COG2239	Acts as a magnesium transporter
AVL55_RS03530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVL55_RS03550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AVL55_RS03555	COG1137	ATPase activity
AVL55_RS03560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AVL55_RS03570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVL55_RS03585	COG1127	ABC transporter
AVL55_RS03590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVL55_RS03595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL55_RS03600	COG2854	intermembrane phospholipid transfer
AVL55_RS03610	COG5007	Belongs to the BolA IbaG family
AVL55_RS03620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL55_RS03625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL55_RS03635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVL55_RS03670	COG0405	Gamma-glutamyltransferase
AVL55_RS03675	COG1024	Enoyl-CoA hydratase
AVL55_RS03745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVL55_RS03775	COG1715	Restriction endonuclease
AVL55_RS03810	COG0393	Putative heavy-metal-binding
AVL55_RS03825	COG4372	Transposase
AVL55_RS03830	COG5433	transposase activity
AVL55_RS03865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL55_RS03880	COG4771	TonB-dependent receptor
AVL55_RS03885	COG0697	spore germination
AVL55_RS03895	COG2205	protein histidine kinase activity
AVL55_RS03895	COG0784	Response regulator, receiver
AVL55_RS03920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVL55_RS03930	COG0126	phosphoglycerate kinase activity
AVL55_RS03935	COG3588	fructose-bisphosphate aldolase
AVL55_RS03940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL55_RS03955	COG5002	protein histidine kinase activity
AVL55_RS03975	COG1538	Outer membrane efflux protein
AVL55_RS03985	COG1506	peptidase
AVL55_RS03985	COG4946	Tricorn protease homolog
AVL55_RS03985	COG0823	Involved in the tonB-independent uptake of proteins
AVL55_RS03990	COG0248	Ppx GppA phosphatase
AVL55_RS03995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVL55_RS04005	COG0573	inorganic phosphate transmembrane transporter activity
AVL55_RS04015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVL55_RS04025	COG0306	phosphate transporter
AVL55_RS04035	COG0583	DNA-binding transcription factor activity
AVL55_RS04045	COG1272	protein, Hemolysin III
AVL55_RS04055	COG1846	Transcriptional regulator
AVL55_RS04060	COG1764	response to oxidative stress
AVL55_RS04075	COG1739	Uncharacterized protein family UPF0029
AVL55_RS04095	COG0583	DNA-binding transcription factor activity
AVL55_RS04100	COG4989	oxidoreductase activity
AVL55_RS04115	COG0420	3'-5' exonuclease activity
AVL55_RS04120	COG0419	ATPase involved in DNA repair
AVL55_RS04130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AVL55_RS04155	COG2986	histidine ammonia-lyase
AVL55_RS04175	COG2971	BadF BadG BcrA BcrD
AVL55_RS04180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AVL55_RS04190	COG0488	(ABC) transporter
AVL55_RS04205	COG0668	transmembrane transport
AVL55_RS04220	COG4771	TonB-dependent receptor
AVL55_RS04225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS04230	COG0842	Transport permease protein
AVL55_RS04230	COG1129	ABC transporter
AVL55_RS04235	COG0842	Transport permease protein
AVL55_RS04240	COG2814	Major facilitator Superfamily
AVL55_RS04280	COG4584	PFAM Integrase catalytic
AVL55_RS04330	COG1346	cytolysis
AVL55_RS04360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVL55_RS04365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVL55_RS04370	COG0513	Belongs to the DEAD box helicase family
AVL55_RS04390	COG3267	Type II secretory pathway component ExeA
AVL55_RS04390	COG3409	Peptidoglycan-binding domain 1 protein
AVL55_RS04415	COG0473	3-isopropylmalate dehydrogenase activity
AVL55_RS04420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVL55_RS04440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVL55_RS04455	COG4555	ABC transporter
AVL55_RS04460	COG1668	transmembrane transport
AVL55_RS04475	COG4133	protoheme IX ABC transporter activity
AVL55_RS04480	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL55_RS04485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL55_RS04490	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL55_RS04500	COG1138	Cytochrome C-type biogenesis protein
AVL55_RS04520	COG2853	Lipoprotein
AVL55_RS04535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVL55_RS04590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVL55_RS04595	COG1555	photosystem II stabilization
AVL55_RS04595	COG1596	polysaccharide export
AVL55_RS04600	COG0473	3-isopropylmalate dehydrogenase activity
AVL55_RS04615	COG1611	Belongs to the LOG family
AVL55_RS04660	COG3098	single-species biofilm formation
AVL55_RS04665	COG0564	pseudouridine synthase activity
AVL55_RS04680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVL55_RS04685	COG0024	Methionine aminopeptidase
AVL55_RS04690	COG0052	Belongs to the universal ribosomal protein uS2 family
AVL55_RS04700	COG0528	UMP kinase activity
AVL55_RS04710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVL55_RS04715	COG0575	Belongs to the CDS family
AVL55_RS04735	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AVL55_RS04740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL55_RS04745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL55_RS04760	COG0587	DNA-directed DNA polymerase activity
AVL55_RS04765	COG0825	malonyl-CoA metabolic process
AVL55_RS04770	COG0037	tRNA processing
AVL55_RS04800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVL55_RS04800	COG0047	phosphoribosylformylglycinamidine synthase activity
AVL55_RS04805	COG2840	Smr protein MutS2
AVL55_RS04840	COG0784	Response regulator, receiver
AVL55_RS04840	COG0835	chemotaxis
AVL55_RS04845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVL55_RS04850	COG1815	bacterial-type flagellum-dependent cell motility
AVL55_RS04865	COG1749	Flagellar hook protein flgE
AVL55_RS04870	COG4787	bacterial-type flagellum-dependent cell motility
AVL55_RS04890	COG3951	Flagellar rod assembly protein muramidase FlgJ
AVL55_RS04890	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVL55_RS04895	COG1256	bacterial-type flagellum assembly
AVL55_RS04915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL55_RS04920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL55_RS04930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AVL55_RS04945	COG1086	Polysaccharide biosynthesis protein
AVL55_RS04950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL55_RS04955	COG1083	cytidylyl-transferase
AVL55_RS04960	COG2089	acid synthase
AVL55_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS04985	COG0318	PFAM AMP-dependent synthetase and ligase
AVL55_RS05010	COG3475	LICD family
AVL55_RS05020	COG1442	glycosyl transferase family 8
AVL55_RS05020	COG1216	Glycosyl transferase, family 2
AVL55_RS05040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL55_RS05055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL55_RS05090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVL55_RS05115	COG1677	Flagellar hook-basal body complex protein FliE
AVL55_RS05120	COG1766	The M ring may be actively involved in energy transduction
AVL55_RS05125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVL55_RS05175	COG1987	bacterial-type flagellum assembly
AVL55_RS05185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVL55_RS05190	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVL55_RS05215	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVL55_RS05220	COG0784	Response regulator, receiver
AVL55_RS05220	COG2198	Histidine kinase
AVL55_RS05220	COG0643	Histidine kinase
AVL55_RS05225	COG2201	protein-glutamate methylesterase activity
AVL55_RS05230	COG1192	Involved in chromosome partitioning
AVL55_RS05240	COG0835	chemotaxis
AVL55_RS05255	COG1410	methionine synthase
AVL55_RS05255	COG0646	methionine synthase
AVL55_RS05260	COG1410	methionine synthase
AVL55_RS05260	COG0646	methionine synthase
AVL55_RS05270	COG3123	guanosine phosphorylase activity
AVL55_RS05280	COG0583	DNA-binding transcription factor activity
AVL55_RS05285	COG0583	DNA-binding transcription factor activity
AVL55_RS05290	COG0288	reversible hydration of carbon dioxide
AVL55_RS05295	COG0659	secondary active sulfate transmembrane transporter activity
AVL55_RS05305	COG1309	transcriptional regulator
AVL55_RS05310	COG3590	peptidase
AVL55_RS05320	COG2137	regulation of response to DNA damage stimulus
AVL55_RS05325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVL55_RS05360	COG0511	ligase activity, forming carbon-carbon bonds
AVL55_RS05360	COG5016	pyruvate
AVL55_RS05365	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AVL55_RS05370	COG4172	Belongs to the ABC transporter superfamily
AVL55_RS05380	COG4171	peptide transport system, permease
AVL55_RS05385	COG4168	peptide transport system, permease
AVL55_RS05390	COG0747	negative chemotaxis
AVL55_RS05395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AVL55_RS05400	COG1842	Phage shock protein A
AVL55_RS05430	COG0625	glutathione transferase activity
AVL55_RS05435	COG1522	sequence-specific DNA binding
AVL55_RS05460	COG4206	TonB-dependent receptor
AVL55_RS05475	COG0811	peptide transport
AVL55_RS05480	COG0811	peptide transport
AVL55_RS05485	COG0848	biopolymer transport protein
AVL55_RS05500	COG1444	tRNA N-acetyltransferase activity
AVL55_RS05540	COG0456	acetyltransferase
AVL55_RS05550	COG0583	DNA-binding transcription factor activity
AVL55_RS05555	COG2814	Major facilitator Superfamily
AVL55_RS05560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL55_RS05565	COG0656	L-ascorbic acid biosynthetic process
AVL55_RS05580	COG1846	Transcriptional regulator
AVL55_RS05605	COG3620	sequence-specific DNA binding
AVL55_RS05610	COG3550	peptidyl-serine autophosphorylation
AVL55_RS05645	COG0668	transmembrane transport
AVL55_RS05715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVL55_RS05735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AVL55_RS05820	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVL55_RS05870	COG0789	Transcriptional regulator
AVL55_RS05885	COG0789	Transcriptional regulator
AVL55_RS05890	COG0640	Transcriptional regulator
AVL55_RS05900	COG1230	cation diffusion facilitator family transporter
AVL55_RS05935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS05950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL55_RS05965	COG0681	Belongs to the peptidase S26 family
AVL55_RS05985	COG1074	ATP-dependent DNA helicase activity
AVL55_RS05995	COG1404	Belongs to the peptidase S8 family
AVL55_RS06000	COG0464	growth
AVL55_RS06020	COG0629	single-stranded DNA binding
AVL55_RS06035	COG0714	Associated with various cellular activities
AVL55_RS06060	COG2003	Belongs to the UPF0758 family
AVL55_RS06080	COG0583	DNA-binding transcription factor activity
AVL55_RS06160	COG0457	Tetratricopeptide repeat
AVL55_RS06175	COG2197	response regulator
AVL55_RS06190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVL55_RS06235	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS06250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVL55_RS06255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVL55_RS06260	COG0564	pseudouridine synthase activity
AVL55_RS06270	COG0612	Peptidase, M16
AVL55_RS06275	COG2918	glutathione biosynthetic process
AVL55_RS06295	COG2840	Smr protein MutS2
AVL55_RS06300	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL55_RS06315	COG2719	SpoVR family
AVL55_RS06320	COG2718	Belongs to the UPF0229 family
AVL55_RS06325	COG2766	serine protein kinase
AVL55_RS06330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVL55_RS06335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVL55_RS06340	COG4771	TonB-dependent receptor
AVL55_RS06365	COG0450	alkyl hydroperoxide reductase
AVL55_RS06370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL55_RS06375	COG2885	chlorophyll binding
AVL55_RS06380	COG0584	glycerophosphoryl diester phosphodiesterase
AVL55_RS06385	COG0346	lactoylglutathione lyase activity
AVL55_RS06390	COG1278	Cold shock
AVL55_RS06405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVL55_RS06410	COG4660	Part of a membrane complex involved in electron transport
AVL55_RS06415	COG4659	FMN binding
AVL55_RS06420	COG4658	electron transport chain
AVL55_RS06425	COG4656	Part of a membrane complex involved in electron transport
AVL55_RS06430	COG2878	Part of a membrane complex involved in electron transport
AVL55_RS06435	COG4657	Part of a membrane complex involved in electron transport
AVL55_RS06450	COG0534	Mate efflux family protein
AVL55_RS06455	COG0556	nucleotide-excision repair
AVL55_RS06470	COG0602	queuosine metabolic process
AVL55_RS06480	COG0367	asparagine synthase
AVL55_RS06500	COG0471	metal ion transport
AVL55_RS06500	COG3273	potassium ion transport
AVL55_RS06515	COG0529	Catalyzes the synthesis of activated sulfate
AVL55_RS06520	COG0175	sulfate reduction
AVL55_RS06525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL55_RS06555	COG2304	oxidoreductase activity
AVL55_RS06575	COG0714	Associated with various cellular activities
AVL55_RS06585	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL55_RS06585	COG1024	Enoyl-CoA hydratase
AVL55_RS06605	COG1025	Belongs to the peptidase M16 family
AVL55_RS06610	COG2062	phosphohistidine phosphatase, SixA
AVL55_RS06620	COG4536	flavin adenine dinucleotide binding
AVL55_RS06625	COG4137	Cytochrome C assembly protein
AVL55_RS06630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVL55_RS06670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS06675	COG1132	(ABC) transporter
AVL55_RS06690	COG0228	four-way junction DNA binding
AVL55_RS06695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVL55_RS06700	COG0336	Belongs to the RNA methyltransferase TrmD family
AVL55_RS06705	COG0335	large ribosomal subunit rRNA binding
AVL55_RS06710	COG2860	membrane
AVL55_RS06720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVL55_RS06725	COG0287	Prephenate dehydrogenase
AVL55_RS06725	COG1605	Chorismate mutase
AVL55_RS06730	COG1605	Chorismate mutase
AVL55_RS06730	COG0077	Prephenate dehydratase
AVL55_RS06735	COG0745	RESPONSE REGULATOR receiver
AVL55_RS06740	COG0023	Translation Initiation Factor
AVL55_RS06770	COG2205	protein histidine kinase activity
AVL55_RS06780	COG2204	response regulator
AVL55_RS06795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVL55_RS06800	COG0494	nUDIX hydrolase
AVL55_RS06805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVL55_RS06810	COG0632	four-way junction helicase activity
AVL55_RS06815	COG2255	four-way junction helicase activity
AVL55_RS06820	COG0824	Thioesterase
AVL55_RS06825	COG0811	peptide transport
AVL55_RS06840	COG0823	Involved in the tonB-independent uptake of proteins
AVL55_RS06845	COG2885	chlorophyll binding
AVL55_RS06850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVL55_RS06865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVL55_RS06880	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL55_RS06885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVL55_RS06895	COG0784	Response regulator, receiver
AVL55_RS06895	COG2205	protein histidine kinase activity
AVL55_RS06920	COG3038	cytochrome b561
AVL55_RS06930	COG1451	nucleotide metabolic process
AVL55_RS06940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS06950	COG1309	transcriptional regulator
AVL55_RS06955	COG4774	siderophore transport
AVL55_RS06975	COG3706	GGDEF domain
AVL55_RS06985	COG3008	intermembrane lipid transfer
AVL55_RS06985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL55_RS06990	COG2995	paraquat-inducible protein a
AVL55_RS07000	COG0017	Asparaginyl-tRNA synthetase
AVL55_RS07015	COG0189	ligase activity
AVL55_RS07050	COG2226	methyltransferase
AVL55_RS07060	COG3340	Belongs to the peptidase S51 family
AVL55_RS07065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVL55_RS07070	COG4139	cobalamin transport
AVL55_RS07080	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVL55_RS07085	COG2205	protein histidine kinase activity
AVL55_RS07090	COG0745	RESPONSE REGULATOR receiver
AVL55_RS07095	COG0569	domain protein
AVL55_RS07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVL55_RS07115	COG5265	(ABC) transporter
AVL55_RS07125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVL55_RS07135	COG0745	RESPONSE REGULATOR receiver
AVL55_RS07155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL55_RS07195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL55_RS07205	COG2755	lipolytic protein G-D-S-L family
AVL55_RS07210	COG4181	ATPase activity
AVL55_RS07215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVL55_RS07220	COG1090	epimerase
AVL55_RS07225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL55_RS07230	COG0628	permease
AVL55_RS07255	COG2350	Protein conserved in bacteria
AVL55_RS07260	COG0159	tryptophan synthase activity
AVL55_RS07270	COG0135	phosphoribosylanthranilate isomerase activity
AVL55_RS07270	COG0134	indole-3-glycerol-phosphate synthase activity
AVL55_RS07275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVL55_RS07285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVL55_RS07290	COG0613	PHP domain protein
AVL55_RS07295	COG0009	L-threonylcarbamoyladenylate synthase
AVL55_RS07305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVL55_RS07315	COG0656	L-ascorbic acid biosynthetic process
AVL55_RS07320	COG0110	maltose O-acetyltransferase activity
AVL55_RS07330	COG2733	membrane
AVL55_RS07335	COG0500	methyltransferase
AVL55_RS07340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL55_RS07345	COG0497	DNA recombination
AVL55_RS07350	COG0783	Belongs to the Dps family
AVL55_RS07355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVL55_RS07365	COG1454	alcohol dehydrogenase
AVL55_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS07380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVL55_RS07385	COG2610	gluconate transmembrane transporter activity
AVL55_RS07390	COG4771	TonB-dependent receptor
AVL55_RS07405	COG0784	Response regulator, receiver
AVL55_RS07405	COG2198	Histidine kinase
AVL55_RS07405	COG2205	protein histidine kinase activity
AVL55_RS07405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL55_RS07410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVL55_RS07420	COG0484	heat shock protein binding
AVL55_RS07425	COG3909	cytochrome
AVL55_RS07430	COG2199	diguanylate cyclase activity
AVL55_RS07430	COG2200	EAL domain
AVL55_RS07430	COG2202	Pas domain
AVL55_RS07445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVL55_RS07455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVL55_RS07460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL55_RS07480	COG0071	Belongs to the small heat shock protein (HSP20) family
AVL55_RS07490	COG0280	phosphate acetyltransferase
AVL55_RS07490	COG0857	belongs to the CobB CobQ family
AVL55_RS07495	COG1228	amidohydrolase
AVL55_RS07500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVL55_RS07505	COG4535	Mg2 and Co2 transporter CorC
AVL55_RS07515	COG1702	phosphate starvation-inducible protein PhoH
AVL55_RS07525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL55_RS07545	COG1607	acyl-coa hydrolase
AVL55_RS07550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVL55_RS07560	COG1115	amino acid carrier protein
AVL55_RS07595	COG0012	GTP binding
AVL55_RS07610	COG1064	alcohol dehydrogenase
AVL55_RS07620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVL55_RS07630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVL55_RS07635	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AVL55_RS07640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVL55_RS07650	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL55_RS07655	COG0784	Response regulator, receiver
AVL55_RS07655	COG3437	response regulator, receiver
AVL55_RS07665	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVL55_RS07675	COG0583	DNA-binding transcription factor activity
AVL55_RS07685	COG2363	Small membrane protein
AVL55_RS07700	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AVL55_RS07705	COG0515	serine threonine protein kinase
AVL55_RS07710	COG2116	formate transmembrane transporter activity
AVL55_RS07725	COG0714	Associated with various cellular activities
AVL55_RS07730	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AVL55_RS07735	COG0033	Phosphoglucomutase
AVL55_RS07740	COG0058	SHG alpha-glucan phosphorylase activity
AVL55_RS07750	COG2988	succinylglutamate desuccinylase activity
AVL55_RS07765	COG1506	peptidase
AVL55_RS07770	COG1301	dicarboxylic acid transport
AVL55_RS07790	COG1393	Belongs to the ArsC family
AVL55_RS07820	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVL55_RS07880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVL55_RS07880	COG0475	glutathione-regulated potassium exporter activity
AVL55_RS07885	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVL55_RS07910	COG1733	regulation of RNA biosynthetic process
AVL55_RS07920	COG5001	Diguanylate cyclase
AVL55_RS07920	COG5002	protein histidine kinase activity
AVL55_RS07920	COG3447	MASE1 domain protein
AVL55_RS07930	COG0402	S-adenosylhomocysteine deaminase activity
AVL55_RS07950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL55_RS07960	COG1309	transcriptional regulator
AVL55_RS07975	COG2252	PERMEase
AVL55_RS07980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL55_RS08000	COG0784	Response regulator, receiver
AVL55_RS08000	COG2205	protein histidine kinase activity
AVL55_RS08015	COG2233	PERMEase
AVL55_RS08035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL55_RS08040	COG0730	response to heat
AVL55_RS08050	COG0154	amidase activity
AVL55_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS08085	COG3001	Fructosamine kinase
AVL55_RS08095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVL55_RS08115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVL55_RS08125	COG1596	polysaccharide export
AVL55_RS08130	COG0489	protein tyrosine kinase activity
AVL55_RS08135	COG4464	protein tyrosine phosphatase activity
AVL55_RS08185	COG1215	transferase activity, transferring glycosyl groups
AVL55_RS08190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVL55_RS08195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVL55_RS08200	COG0438	transferase activity, transferring glycosyl groups
AVL55_RS08230	COG0297	glycogen (starch) synthase activity
AVL55_RS08235	COG4372	Transposase
AVL55_RS08250	COG0072	phenylalanine-tRNA ligase activity
AVL55_RS08250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL55_RS08285	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL55_RS08290	COG2096	Adenosyltransferase
AVL55_RS08300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVL55_RS08310	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL55_RS08330	COG0708	Exodeoxyribonuclease III
AVL55_RS08365	COG2814	Major facilitator Superfamily
AVL55_RS08400	COG4770	biotin carboxylase activity
AVL55_RS08405	COG1024	Enoyl-CoA hydratase
AVL55_RS08410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVL55_RS08415	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS08420	COG0789	Transcriptional regulator
AVL55_RS08425	COG0183	Belongs to the thiolase family
AVL55_RS08450	COG2925	Exonuclease
AVL55_RS08455	COG2205	protein histidine kinase activity
AVL55_RS08455	COG0784	Response regulator, receiver
AVL55_RS08455	COG5002	protein histidine kinase activity
AVL55_RS08495	COG1643	Atp-dependent helicase
AVL55_RS08515	COG3321	synthase
AVL55_RS08515	COG0604	alcohol dehydrogenase
AVL55_RS08520	COG0328	RNA-DNA hybrid ribonuclease activity
AVL55_RS08525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL55_RS08550	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVL55_RS08555	COG1136	(ABC) transporter
AVL55_RS08560	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL55_RS08565	COG1301	dicarboxylic acid transport
AVL55_RS08570	COG4932	domain protein
AVL55_RS08570	COG2373	Large extracellular alpha-helical protein
AVL55_RS08570	COG1388	LysM domain
AVL55_RS08575	COG3724	N-succinylarginine dihydrolase activity
AVL55_RS08580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVL55_RS08585	COG3122	Protein conserved in bacteria
AVL55_RS08595	COG0583	DNA-binding transcription factor activity
AVL55_RS08600	COG0746	molybdenum cofactor guanylyltransferase activity
AVL55_RS08605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVL55_RS08610	COG0243	molybdopterin cofactor binding
AVL55_RS08615	COG2153	protein acetylation
AVL55_RS08625	COG5002	protein histidine kinase activity
AVL55_RS08635	COG1530	ribonuclease E activity
AVL55_RS08640	COG0564	pseudouridine synthase activity
AVL55_RS08645	COG0546	phosphoglycolate phosphatase activity
AVL55_RS08650	COG0424	maF-like protein
AVL55_RS08655	COG1399	metal-binding, possibly nucleic acid-binding protein
AVL55_RS08665	COG0416	fatty acid biosynthetic process
AVL55_RS08670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVL55_RS08675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVL55_RS08685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVL55_RS08690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVL55_RS08695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVL55_RS08700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVL55_RS08715	COG0084	hydrolase, TatD family'
AVL55_RS08725	COG0702	epimerase
AVL55_RS08730	COG3706	GGDEF domain
AVL55_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS08760	COG0596	Alpha beta hydrolase
AVL55_RS08765	COG1024	Enoyl-CoA hydratase
AVL55_RS08765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL55_RS08770	COG0183	Belongs to the thiolase family
AVL55_RS08775	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS08790	COG2390	Transcriptional regulator
AVL55_RS08815	COG0668	transmembrane transport
AVL55_RS08840	COG2198	Histidine kinase
AVL55_RS08840	COG2205	protein histidine kinase activity
AVL55_RS08840	COG0784	Response regulator, receiver
AVL55_RS08845	COG3437	response regulator, receiver
AVL55_RS08855	COG0195	Participates in both transcription termination and antitermination
AVL55_RS08870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVL55_RS08880	COG1187	pseudouridine synthase activity
AVL55_RS08890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL55_RS08890	COG3153	acetyltransferase
AVL55_RS08955	COG1032	radical SAM domain protein
AVL55_RS08990	COG1131	(ABC) transporter
AVL55_RS09000	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS09010	COG2867	negative regulation of translational initiation
AVL55_RS09015	COG2914	Belongs to the UPF0125 (RnfH) family
AVL55_RS09025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVL55_RS09030	COG4771	TonB-dependent receptor
AVL55_RS09035	COG0457	Tetratricopeptide repeat
AVL55_RS09045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVL55_RS09045	COG0574	Belongs to the PEP-utilizing enzyme family
AVL55_RS09075	COG2850	peptidyl-arginine hydroxylation
AVL55_RS09085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVL55_RS09090	COG2915	High frequency lysogenization protein hflD homolog
AVL55_RS09095	COG0482	sulfurtransferase activity
AVL55_RS09100	COG1187	pseudouridine synthase activity
AVL55_RS09110	COG1278	Cold shock
AVL55_RS09115	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVL55_RS09120	COG0542	response to heat
AVL55_RS09125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVL55_RS09130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVL55_RS09135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVL55_RS09140	COG0492	ferredoxin-NADP+ reductase activity
AVL55_RS09145	COG3092	negative regulation of chromosome organization
AVL55_RS09150	COG3091	SprT-like family
AVL55_RS09155	COG0616	signal peptide processing
AVL55_RS09170	COG0778	Nitroreductase
AVL55_RS09180	COG0252	asparaginase activity
AVL55_RS09185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVL55_RS09190	COG0321	lipoyl(octanoyl) transferase activity
AVL55_RS09195	COG2921	Belongs to the UPF0250 family
AVL55_RS09200	COG1686	Belongs to the peptidase S11 family
AVL55_RS09205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL55_RS09210	COG0772	Belongs to the SEDS family
AVL55_RS09215	COG0768	penicillin binding
AVL55_RS09220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVL55_RS09225	COG0799	negative regulation of ribosome biogenesis
AVL55_RS09230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVL55_RS09235	COG1466	dna polymerase III delta subunit
AVL55_RS09240	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AVL55_RS09245	COG0495	leucyl-tRNA aminoacylation
AVL55_RS09255	COG1067	ATP-dependent peptidase activity
AVL55_RS09275	COG1534	Rna-binding protein
AVL55_RS09280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVL55_RS09285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL55_RS09290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVL55_RS09295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVL55_RS09300	COG0149	triose-phosphate isomerase activity
AVL55_RS09305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL55_RS09330	COG1803	Methylglyoxal synthase
AVL55_RS09330	COG1597	lipid kinase activity
AVL55_RS09340	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS09345	COG0561	phosphatase activity
AVL55_RS09360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL55_RS09365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVL55_RS09370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVL55_RS09385	COG1185	polyribonucleotide nucleotidyltransferase activity
AVL55_RS09465	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AVL55_RS09470	COG1196	nuclear chromosome segregation
AVL55_RS09480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVL55_RS09500	COG1132	(ABC) transporter
AVL55_RS09505	COG1663	tetraacyldisaccharide 4'-kinase activity
AVL55_RS09540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVL55_RS09545	COG0435	Glutathione S-transferase
AVL55_RS09550	COG1741	Belongs to the pirin family
AVL55_RS09575	COG0372	Belongs to the citrate synthase family
AVL55_RS09585	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVL55_RS09590	COG1053	succinate dehydrogenase
AVL55_RS09595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVL55_RS09600	COG0567	Dehydrogenase, E1 component
AVL55_RS09605	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL55_RS09640	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL55_RS09665	COG0366	Alpha amylase catalytic
AVL55_RS09675	COG0366	Alpha amylase catalytic
AVL55_RS09675	COG1874	Beta-galactosidase
AVL55_RS09680	COG1609	Transcriptional regulator
AVL55_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS09695	COG2267	carboxylic ester hydrolase activity
AVL55_RS09705	COG0616	signal peptide processing
AVL55_RS09720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVL55_RS09725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL55_RS09730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL55_RS09735	COG0386	Belongs to the glutathione peroxidase family
AVL55_RS09740	COG2084	Dehydrogenase
AVL55_RS09750	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS09755	COG1024	Enoyl-CoA hydratase
AVL55_RS09760	COG2226	methyltransferase
AVL55_RS09770	COG3083	sulfuric ester hydrolase activity
AVL55_RS09775	COG3082	Protein of unknown function (DUF1414)
AVL55_RS09780	COG3081	Nucleoid-associated protein
AVL55_RS09790	COG0739	heme binding
AVL55_RS09790	COG0741	lytic transglycosylase activity
AVL55_RS09790	COG1196	nuclear chromosome segregation
AVL55_RS09810	COG3275	phosphorelay sensor kinase activity
AVL55_RS09815	COG3279	Response regulator of the LytR AlgR family
AVL55_RS09820	COG0205	6-phosphofructokinase activity
AVL55_RS09835	COG2205	protein histidine kinase activity
AVL55_RS09835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL55_RS09845	COG1054	Belongs to the UPF0176 family
AVL55_RS09865	COG4221	oxidoreductase activity
AVL55_RS09865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL55_RS09865	COG0604	alcohol dehydrogenase
AVL55_RS09865	COG3321	synthase
AVL55_RS09870	COG4221	oxidoreductase activity
AVL55_RS09875	COG0583	DNA-binding transcription factor activity
AVL55_RS09925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVL55_RS09950	COG0513	Belongs to the DEAD box helicase family
AVL55_RS09960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVL55_RS09965	COG0583	DNA-binding transcription factor activity
AVL55_RS09985	COG1760	l-serine dehydratase
AVL55_RS10005	COG1322	Protein conserved in bacteria
AVL55_RS10010	COG1404	Belongs to the peptidase S8 family
AVL55_RS10015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVL55_RS10020	COG0022	dehydrogenase e1 component
AVL55_RS10030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVL55_RS10035	COG0515	serine threonine protein kinase
AVL55_RS10040	COG1946	Acyl-CoA thioesterase
AVL55_RS10050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL55_RS10060	COG1956	GAF domain-containing protein
AVL55_RS10075	COG0793	Belongs to the peptidase S41A family
AVL55_RS10080	COG0733	neurotransmitter:sodium symporter activity
AVL55_RS10085	COG1757	Na H antiporter
AVL55_RS10090	COG0308	aminopeptidase N
AVL55_RS10125	COG0167	dihydroorotate dehydrogenase activity
AVL55_RS10140	COG0488	(ABC) transporter
AVL55_RS10150	COG3130	regulation of translation
AVL55_RS10155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL55_RS10165	COG0415	Belongs to the DNA photolyase family
AVL55_RS10195	COG1192	Involved in chromosome partitioning
AVL55_RS10280	COG1192	Involved in chromosome partitioning
AVL55_RS10355	COG3706	GGDEF domain
AVL55_RS10375	COG5001	Diguanylate cyclase
AVL55_RS10375	COG3300	MHYT domain
AVL55_RS10410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL55_RS10455	COG0210	DNA helicase
AVL55_RS10660	COG0415	Belongs to the DNA photolyase family
AVL55_RS10665	COG0415	Belongs to the DNA photolyase family
AVL55_RS10670	COG0415	Belongs to the DNA photolyase family
AVL55_RS10675	COG3046	protein related to deoxyribodipyrimidine photolyase
AVL55_RS10685	COG4974	Belongs to the 'phage' integrase family
AVL55_RS10695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL55_RS10700	COG0589	response to stress
AVL55_RS10710	COG0069	glutamate synthase activity
AVL55_RS10725	COG2193	ferroxidase activity
AVL55_RS10735	COG3278	Belongs to the heme-copper respiratory oxidase family
AVL55_RS10750	COG2010	Cytochrome c
AVL55_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL55_RS10780	COG0589	response to stress
AVL55_RS10785	COG0037	tRNA processing
AVL55_RS10790	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVL55_RS10810	COG1280	lysine exporter protein (LysE YggA)
AVL55_RS10820	COG2897	thiosulfate sulfurtransferase activity
AVL55_RS10825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AVL55_RS10830	COG3148	PFAM DTW domain containing protein
AVL55_RS10855	COG0322	excinuclease ABC activity
AVL55_RS10860	COG2197	response regulator
AVL55_RS10865	COG1741	Belongs to the pirin family
AVL55_RS10895	COG2259	Doxx family
AVL55_RS10900	COG0583	DNA-binding transcription factor activity
AVL55_RS10915	COG0670	Belongs to the BI1 family
AVL55_RS10920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AVL55_RS10935	COG2920	part of a sulfur-relay system
AVL55_RS10965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVL55_RS10970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVL55_RS10975	COG0531	amino acid
AVL55_RS10975	COG1674	ftsk spoiiie
AVL55_RS10985	COG0686	Belongs to the AlaDH PNT family
AVL55_RS10990	COG0284	orotidine-5'-phosphate decarboxylase activity
AVL55_RS10995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AVL55_RS11010	COG0776	regulation of translation
AVL55_RS11015	COG0539	negative regulation of cytoplasmic translation
AVL55_RS11020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVL55_RS11025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVL55_RS11030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVL55_RS11040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL55_RS11045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL55_RS11050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL55_RS11055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL55_RS11115	COG0210	DNA helicase
AVL55_RS11195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL55_RS11200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVL55_RS11205	COG4221	oxidoreductase activity
AVL55_RS11220	COG4251	negative regulation of phosphorylation
AVL55_RS11220	COG5001	Diguanylate cyclase
AVL55_RS11220	COG3706	GGDEF domain
AVL55_RS11220	COG2203	Gaf domain
AVL55_RS11235	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AVL55_RS11240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVL55_RS11250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVL55_RS11260	COG4783	chaperone-mediated protein folding
AVL55_RS11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVL55_RS11270	COG1393	Belongs to the ArsC family
AVL55_RS11305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVL55_RS11315	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS11345	COG3769	mannosylglycerate metabolic process
AVL55_RS11350	COG1215	transferase activity, transferring glycosyl groups
AVL55_RS11365	COG0303	'Molybdopterin
AVL55_RS11370	COG0534	Mate efflux family protein
AVL55_RS11390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVL55_RS11415	COG0701	Predicted permease
AVL55_RS11435	COG1671	Belongs to the UPF0178 family
AVL55_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS11450	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS11455	COG2207	Transcriptional regulator
AVL55_RS11455	COG0662	Cupin 2, conserved barrel domain protein
AVL55_RS11470	COG1505	serine-type exopeptidase activity
AVL55_RS11510	COG0596	Alpha beta hydrolase
AVL55_RS11520	COG0716	FMN binding
AVL55_RS11525	COG3385	transposase activity
AVL55_RS11535	COG0735	belongs to the Fur family
AVL55_RS11545	COG1984	allophanate hydrolase subunit 2
AVL55_RS11550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AVL55_RS11555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVL55_RS11560	COG2996	Protein conserved in bacteria
AVL55_RS11565	COG1765	OsmC-like protein
AVL55_RS11570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS11580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS11595	COG0436	Aminotransferase
AVL55_RS11600	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVL55_RS11605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVL55_RS11630	COG3012	SEC-C Motif Domain Protein
AVL55_RS11635	COG0604	alcohol dehydrogenase
AVL55_RS11645	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS11655	COG4771	TonB-dependent receptor
AVL55_RS11680	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVL55_RS11700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AVL55_RS11705	COG0315	cyclic pyranopterin monophosphate synthase activity
AVL55_RS11710	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVL55_RS11715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL55_RS11725	COG2423	ornithine cyclodeaminase activity
AVL55_RS11730	COG0436	Aminotransferase
AVL55_RS11735	COG1522	sequence-specific DNA binding
AVL55_RS11750	COG0826	peptidase U32
AVL55_RS11755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVL55_RS11760	COG0436	Aminotransferase
AVL55_RS11765	COG3268	Saccharopine dehydrogenase
AVL55_RS11770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL55_RS11795	COG4771	TonB-dependent receptor
AVL55_RS11840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVL55_RS11845	COG1074	ATP-dependent DNA helicase activity
AVL55_RS11850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AVL55_RS11895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVL55_RS11925	COG1022	Amp-dependent synthetase and ligase
AVL55_RS11935	COG5001	Diguanylate cyclase
AVL55_RS11935	COG3300	MHYT domain
AVL55_RS11955	COG0583	DNA-binding transcription factor activity
AVL55_RS11970	COG0640	Transcriptional regulator
AVL55_RS11990	COG2204	response regulator
AVL55_RS12000	COG4251	negative regulation of phosphorylation
AVL55_RS12005	COG0784	Response regulator, receiver
AVL55_RS12010	COG2205	protein histidine kinase activity
AVL55_RS12010	COG0784	Response regulator, receiver
AVL55_RS12055	COG3139	Protein of unknown function (DUF1315)
AVL55_RS12065	COG1115	amino acid carrier protein
AVL55_RS12070	COG2866	Carboxypeptidase
AVL55_RS12090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVL55_RS12100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVL55_RS12105	COG1640	4-alpha-glucanotransferase
AVL55_RS12115	COG0676	glucose-6-phosphate 1-epimerase activity
AVL55_RS12120	COG0800	Aldolase
AVL55_RS12130	COG0129	dihydroxy-acid dehydratase activity
AVL55_RS12140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVL55_RS12145	COG1737	Transcriptional regulator
AVL55_RS12150	COG0469	pyruvate kinase activity
AVL55_RS12155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL55_RS12175	COG2823	Periplasmic or secreted lipoprotein
AVL55_RS12200	COG3665	Urea carboxylase-associated protein
AVL55_RS12230	COG2356	endonuclease I
AVL55_RS12250	COG0583	DNA-binding transcription factor activity
AVL55_RS12260	COG1979	alcohol dehydrogenase
AVL55_RS12265	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS12280	COG0753	catalase activity
AVL55_RS12355	COG0789	Transcriptional regulator
AVL55_RS12415	COG0471	metal ion transport
AVL55_RS12430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL55_RS12430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL55_RS12435	COG0668	transmembrane transport
AVL55_RS12440	COG2226	methyltransferase
AVL55_RS12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL55_RS12450	COG0741	lytic transglycosylase activity
AVL55_RS12450	COG1388	LysM domain
AVL55_RS12460	COG0215	cysteine-tRNA ligase activity
AVL55_RS12465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL55_RS12475	COG1785	Belongs to the alkaline phosphatase family
AVL55_RS12480	COG1785	Belongs to the alkaline phosphatase family
AVL55_RS12495	COG2268	Band 7 protein
AVL55_RS12505	COG1733	regulation of RNA biosynthetic process
AVL55_RS12510	COG0604	alcohol dehydrogenase
AVL55_RS12515	COG1063	alcohol dehydrogenase
AVL55_RS12520	COG0583	DNA-binding transcription factor activity
AVL55_RS12545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVL55_RS12550	COG1286	toxin biosynthetic process
AVL55_RS12555	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AVL55_RS12560	COG0285	dihydrofolate synthase activity
AVL55_RS12590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL55_RS12630	COG3335	DDE superfamily endonuclease
AVL55_RS12650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVL55_RS12655	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVL55_RS12655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVL55_RS12705	COG1119	ATPase activity
AVL55_RS12720	COG2169	Transcriptional regulator
AVL55_RS12725	COG1335	isochorismatase
AVL55_RS12735	COG2031	fatty acid transporter
AVL55_RS12750	COG0612	Peptidase, M16
AVL55_RS12765	COG3101	peptidyl-lysine hydroxylation
AVL55_RS12790	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL55_RS12790	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS12815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL55_RS12825	COG4399	Belongs to the UPF0754 family
AVL55_RS12855	COG2186	Transcriptional regulator
AVL55_RS12865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVL55_RS12870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVL55_RS12875	COG2983	Belongs to the UPF0260 family
AVL55_RS12880	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVL55_RS12895	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVL55_RS12900	COG0318	PFAM AMP-dependent synthetase and ligase
AVL55_RS12905	COG2267	carboxylic ester hydrolase activity
AVL55_RS12920	COG1214	PFAM Peptidase M22, glycoprotease
AVL55_RS12925	COG1199	ATP-dependent helicase activity
AVL55_RS13010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVL55_RS13015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVL55_RS13020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL55_RS13025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVL55_RS13025	COG0131	Imidazoleglycerol-phosphate dehydratase
AVL55_RS13030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVL55_RS13050	COG2116	formate transmembrane transporter activity
AVL55_RS13055	COG0612	Peptidase, M16
AVL55_RS13060	COG0681	Belongs to the peptidase S26 family
AVL55_RS13085	COG0326	Molecular chaperone. Has ATPase activity
AVL55_RS13090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVL55_RS13115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVL55_RS13120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVL55_RS13130	COG3220	belongs to the UPF0276 family
AVL55_RS13155	COG4555	ABC transporter
AVL55_RS13195	COG1183	phosphatidylcholine synthase activity
AVL55_RS13215	COG0277	FAD linked oxidase domain protein
AVL55_RS13220	COG1620	l-lactate permease
AVL55_RS13240	COG0542	response to heat
AVL55_RS13265	COG1595	DNA-templated transcription, initiation
AVL55_RS13280	COG4221	oxidoreductase activity
AVL55_RS13295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVL55_RS13305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVL55_RS13315	COG0142	geranyltranstransferase activity
AVL55_RS13325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVL55_RS13330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVL55_RS13340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVL55_RS13355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL55_RS13355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL55_RS13370	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL55_RS13375	COG0488	(ABC) transporter
AVL55_RS13385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AVL55_RS13395	COG0560	Phosphoserine phosphatase
AVL55_RS13405	COG0084	hydrolase, TatD family'
AVL55_RS13420	COG0571	ribonuclease III activity
AVL55_RS13450	COG1595	DNA-templated transcription, initiation
AVL55_RS13455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVL55_RS13470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVL55_RS13550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVL55_RS13555	COG1047	Peptidyl-prolyl cis-trans
AVL55_RS13565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVL55_RS13570	COG0196	riboflavin kinase activity
AVL55_RS13575	COG0728	peptidoglycan biosynthetic process
AVL55_RS13580	COG0268	Binds directly to 16S ribosomal RNA
AVL55_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS13600	COG0385	Bile acid
AVL55_RS13625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL55_RS13630	COG0776	regulation of translation
AVL55_RS13635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVL55_RS13640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVL55_RS13645	COG0740	serine-type endopeptidase activity
AVL55_RS13650	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVL55_RS13695	COG1720	tRNA m6t6A37 methyltransferase activity
AVL55_RS13705	COG1234	tRNA 3'-trailer cleavage
AVL55_RS13715	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL55_RS13730	COG0517	IMP dehydrogenase activity
AVL55_RS13730	COG0516	GMP reductase activity
AVL55_RS13735	COG1570	exodeoxyribonuclease VII activity
AVL55_RS13755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL55_RS13760	COG2976	Protein conserved in bacteria
AVL55_RS13780	COG3063	Type IV pilus biogenesis stability protein PilW
AVL55_RS13785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVL55_RS13795	COG2166	iron-sulfur cluster assembly
AVL55_RS13810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVL55_RS13815	COG0719	Fe-S assembly protein
AVL55_RS13820	COG0396	ATPase activity
AVL55_RS13825	COG0719	Fe-S assembly protein
AVL55_RS13830	COG1104	cysteine desulfurase activity
AVL55_RS13835	COG1959	2 iron, 2 sulfur cluster binding
AVL55_RS13845	COG1045	serine acetyltransferase
AVL55_RS13850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVL55_RS13855	COG0483	inositol monophosphate 1-phosphatase activity
AVL55_RS13860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL55_RS13865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL55_RS13870	COG1862	Preprotein translocase
AVL55_RS13875	COG0343	queuine tRNA-ribosyltransferase activity
AVL55_RS13895	COG1842	Phage shock protein A
AVL55_RS13900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVL55_RS13920	COG0754	glutathionylspermidine amidase activity
AVL55_RS13950	COG2066	Belongs to the glutaminase family
AVL55_RS13955	COG1785	Belongs to the alkaline phosphatase family
AVL55_RS13960	COG0745	RESPONSE REGULATOR receiver
AVL55_RS14005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL55_RS14040	COG0438	transferase activity, transferring glycosyl groups
AVL55_RS14055	COG0367	asparagine synthase
AVL55_RS14070	COG1442	glycosyl transferase family 8
AVL55_RS14070	COG1216	Glycosyl transferase, family 2
AVL55_RS14085	COG2327	Polysaccharide pyruvyl transferase
AVL55_RS14120	COG0438	transferase activity, transferring glycosyl groups
AVL55_RS14150	COG0489	protein tyrosine kinase activity
AVL55_RS14160	COG3267	Type II secretory pathway component ExeA
AVL55_RS14160	COG3409	Peptidoglycan-binding domain 1 protein
AVL55_RS14165	COG2827	Endonuclease containing a URI domain
AVL55_RS14185	COG1560	Kdo2-lipid A biosynthetic process
AVL55_RS14200	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS14205	COG5433	transposase activity
AVL55_RS14230	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AVL55_RS14240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVL55_RS14250	COG1131	(ABC) transporter
AVL55_RS14280	COG0679	Auxin Efflux Carrier
AVL55_RS14290	COG3706	GGDEF domain
AVL55_RS14295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVL55_RS14330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVL55_RS14370	COG0628	permease
AVL55_RS14380	COG0673	inositol 2-dehydrogenase activity
AVL55_RS14410	COG3604	Transcriptional regulator
AVL55_RS14415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVL55_RS14415	COG1017	nitric oxide dioxygenase activity
AVL55_RS14420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL55_RS14435	COG1435	thymidine kinase activity
AVL55_RS14445	COG1609	Transcriptional regulator
AVL55_RS14450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVL55_RS14470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVL55_RS14475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL55_RS14490	COG1982	Orn Lys Arg decarboxylase major
AVL55_RS14520	COG1012	belongs to the aldehyde dehydrogenase family
AVL55_RS14565	COG1960	acyl-CoA dehydrogenase activity
AVL55_RS14625	COG2080	2 iron, 2 sulfur cluster binding
AVL55_RS14630	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVL55_RS14635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL55_RS14645	COG0601	transmembrane transport
AVL55_RS14650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVL55_RS14655	COG4172	Belongs to the ABC transporter superfamily
AVL55_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
AVL55_RS14665	COG4221	oxidoreductase activity
AVL55_RS14670	COG0693	protein deglycase activity
AVL55_RS14675	COG1295	ribonuclease BN
AVL55_RS14710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL55_RS14810	COG0339	signal peptide processing
AVL55_RS14815	COG0583	DNA-binding transcription factor activity
AVL55_RS14850	COG0514	ATP-dependent DNA helicase (RecQ)
AVL55_RS14865	COG3850	Histidine kinase
AVL55_RS14865	COG3437	response regulator, receiver
AVL55_RS14865	COG2205	protein histidine kinase activity
AVL55_RS14865	COG4999	Histidine kinase
AVL55_RS14900	COG0830	nickel cation binding
AVL55_RS14925	COG0829	nickel cation binding
AVL55_RS14960	COG0784	Response regulator, receiver
AVL55_RS14960	COG2198	Histidine kinase
AVL55_RS14960	COG2205	protein histidine kinase activity
AVL55_RS14965	COG0745	RESPONSE REGULATOR receiver
AVL55_RS14970	COG3177	Filamentation induced by cAMP protein fic
AVL55_RS14975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVL55_RS14975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVL55_RS14990	COG0583	DNA-binding transcription factor activity
AVL55_RS15015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL55_RS15020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL55_RS15025	COG0006	proline dipeptidase activity
AVL55_RS15040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL55_RS15050	COG2205	protein histidine kinase activity
AVL55_RS15060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVL55_RS15065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVL55_RS15070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL55_RS15090	COG3313	Fe-S protein
AVL55_RS15115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL55_RS15120	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL55_RS15125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AVL55_RS15145	COG3577	Aspartyl protease
AVL55_RS15150	COG0157	Belongs to the NadC ModD family
AVL55_RS15160	COG1459	type II secretion system
AVL55_RS15165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVL55_RS15170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVL55_RS15170	COG0237	dephospho-CoA kinase activity
AVL55_RS15175	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVL55_RS15180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVL55_RS15185	COG3608	succinylglutamate desuccinylase aspartoacylase
AVL55_RS15190	COG0494	nUDIX hydrolase
AVL55_RS15200	COG0739	heme binding
AVL55_RS15205	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVL55_RS15210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVL55_RS15215	COG0849	cell division
AVL55_RS15220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVL55_RS15225	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVL55_RS15230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL55_RS15240	COG0772	Belongs to the SEDS family
AVL55_RS15245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVL55_RS15255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVL55_RS15260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVL55_RS15265	COG0768	penicillin binding
AVL55_RS15270	COG3116	cell division
AVL55_RS15280	COG2001	Belongs to the MraZ family
AVL55_RS15300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL55_RS15305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS15325	COG0678	peroxiredoxin activity
AVL55_RS15325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL55_RS15350	COG2204	response regulator
AVL55_RS15375	COG0668	transmembrane transport
AVL55_RS15380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVL55_RS15385	COG0189	ligase activity
AVL55_RS15390	COG1678	Uncharacterized ACR, COG1678
AVL55_RS15395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVL55_RS15420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVL55_RS15425	COG0762	integral membrane protein
AVL55_RS15435	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS15435	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL55_RS15460	COG1764	response to oxidative stress
AVL55_RS15465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL55_RS15475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AVL55_RS15485	COG2814	Major facilitator Superfamily
AVL55_RS15490	COG0724	RNA recognition motif
AVL55_RS15515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVL55_RS15520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AVL55_RS15525	COG0083	homoserine kinase activity
AVL55_RS15540	COG0583	DNA-binding transcription factor activity
AVL55_RS15555	COG0640	Transcriptional regulator
AVL55_RS15565	COG0431	NADPH-dependent FMN reductase
AVL55_RS15570	COG0798	PFAM Bile acid sodium symporter
AVL55_RS15575	COG2201	protein-glutamate methylesterase activity
AVL55_RS15580	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AVL55_RS15590	COG0642	Histidine kinase
AVL55_RS15610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AVL55_RS15640	COG1748	Saccharopine dehydrogenase
AVL55_RS15660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVL55_RS15665	COG3107	peptidoglycan biosynthetic process
AVL55_RS15685	COG2823	Periplasmic or secreted lipoprotein
AVL55_RS15705	COG4585	Histidine kinase
AVL55_RS15710	COG2197	response regulator
AVL55_RS15725	COG4771	TonB-dependent receptor
AVL55_RS15735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVL55_RS15740	COG0372	Belongs to the citrate synthase family
AVL55_RS15745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVL55_RS15750	COG2828	Protein conserved in bacteria
AVL55_RS15755	COG2203	Gaf domain
AVL55_RS15755	COG2199	diguanylate cyclase activity
AVL55_RS15775	COG0784	Response regulator, receiver
AVL55_RS15775	COG2198	Histidine kinase
AVL55_RS15775	COG5002	protein histidine kinase activity
AVL55_RS15785	COG0069	glutamate synthase activity
AVL55_RS15785	COG0070	glutamate synthase
AVL55_RS15785	COG0067	glutamate synthase
AVL55_RS15790	COG0493	'glutamate synthase
AVL55_RS15805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL55_RS15810	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AVL55_RS15815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVL55_RS15820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL55_RS15835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVL55_RS15840	COG5507	3-demethylubiquinone-9 3-methyltransferase
AVL55_RS15850	COG3385	transposase activity
AVL55_RS15855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVL55_RS15860	COG0739	heme binding
AVL55_RS15860	COG0741	lytic transglycosylase activity
AVL55_RS15860	COG1196	nuclear chromosome segregation
AVL55_RS15865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVL55_RS15875	COG0738	Major facilitator superfamily
AVL55_RS15885	COG1902	pentaerythritol trinitrate reductase activity
AVL55_RS15900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL55_RS15905	COG0625	glutathione transferase activity
AVL55_RS15925	COG2894	cell division
AVL55_RS15930	COG0850	regulation of cytokinetic process
AVL55_RS15965	COG1981	membrane
AVL55_RS15980	COG1914	H( )-stimulated, divalent metal cation uptake system
AVL55_RS15990	COG0745	RESPONSE REGULATOR receiver
AVL55_RS15995	COG1217	gtp-binding protein TYPA
AVL55_RS16000	COG0174	glutamine synthetase
AVL55_RS16010	COG3852	Histidine kinase
AVL55_RS16015	COG2204	response regulator
AVL55_RS16020	COG3437	response regulator, receiver
AVL55_RS16060	COG0525	valine-tRNA ligase activity
AVL55_RS16065	COG2927	DNA polymerase III (CHI subunit)
AVL55_RS16070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVL55_RS16075	COG0795	lipopolysaccharide-transporting ATPase activity
AVL55_RS16080	COG0795	lipopolysaccharide-transporting ATPase activity
AVL55_RS16145	COG4251	negative regulation of phosphorylation
AVL55_RS16150	COG2133	pyrroloquinoline quinone binding
AVL55_RS16190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVL55_RS16225	COG3341	Caulimovirus viroplasmin
AVL55_RS16225	COG0328	RNA-DNA hybrid ribonuclease activity
AVL55_RS16245	COG4974	Belongs to the 'phage' integrase family
AVL55_RS16260	COG2856	Zn peptidase
AVL55_RS16280	COG0840	transmembrane signaling receptor activity
AVL55_RS16285	COG3588	fructose-bisphosphate aldolase
AVL55_RS16315	COG3842	ATPase activity
AVL55_RS16320	COG3842	ATPase activity
AVL55_RS16330	COG0149	triose-phosphate isomerase activity
AVL55_RS16335	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AVL55_RS16340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AVL55_RS16350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVL55_RS16355	COG3842	ATPase activity
AVL55_RS16405	COG2205	protein histidine kinase activity
AVL55_RS16415	COG3901	Regulator of nitric oxide reductase transcription
AVL55_RS16415	COG0348	domain, Protein
AVL55_RS16425	COG2197	response regulator
AVL55_RS16455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVL55_RS16470	COG4771	TonB-dependent receptor
AVL55_RS16480	COG0583	DNA-binding transcription factor activity
AVL55_RS16485	COG1304	FMN binding
AVL55_RS16490	COG0277	FAD linked oxidase domain protein
AVL55_RS16500	COG1462	curli production assembly transport component CsgG
AVL55_RS16530	COG2197	response regulator
AVL55_RS16545	COG0513	Belongs to the DEAD box helicase family
AVL55_RS16560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVL55_RS16575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL55_RS16580	COG2010	Cytochrome c
AVL55_RS16580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL55_RS16595	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVL55_RS16595	COG3264	Mechanosensitive ion channel
AVL55_RS16635	COG0730	response to heat
AVL55_RS16640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL55_RS16645	COG4191	Histidine kinase
AVL55_RS16655	COG0417	DNA replication proofreading
AVL55_RS16665	COG0318	PFAM AMP-dependent synthetase and ligase
AVL55_RS16720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL55_RS16730	COG1573	uracil-dna glycosylase
AVL55_RS16735	COG5001	Diguanylate cyclase
AVL55_RS16735	COG3300	MHYT domain
AVL55_RS16755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL55_RS16775	COG1983	PspC domain protein
AVL55_RS16780	COG1842	Phage shock protein A
AVL55_RS16790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL55_RS16815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVL55_RS16825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVL55_RS16830	COG0204	Acyl-transferase
AVL55_RS16835	COG0204	Acyl-transferase
AVL55_RS16840	COG0668	transmembrane transport
AVL55_RS16855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVL55_RS16860	COG0733	neurotransmitter:sodium symporter activity
AVL55_RS16875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL55_RS16890	COG0716	FMN binding
AVL55_RS16900	COG0848	biopolymer transport protein
AVL55_RS16915	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVL55_RS16920	COG0702	epimerase
AVL55_RS16935	COG5002	protein histidine kinase activity
AVL55_RS16935	COG5001	Diguanylate cyclase
AVL55_RS16945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AVL55_RS16955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL55_RS16965	COG0121	glutamine amidotransferase
AVL55_RS16985	COG4628	conserved protein (DUF2132)
AVL55_RS17005	COG3265	gluconokinase activity
AVL55_RS17010	COG1609	Transcriptional regulator
AVL55_RS17015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL55_RS17025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVL55_RS17040	COG1477	protein flavinylation
AVL55_RS17045	COG2871	sodium ion transport
AVL55_RS17050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL55_RS17055	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL55_RS17060	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL55_RS17065	COG1805	sodium ion transport
AVL55_RS17070	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL55_RS17075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVL55_RS17080	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL55_RS17085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AVL55_RS17090	COG0039	L-malate dehydrogenase activity
AVL55_RS17095	COG1438	arginine binding
AVL55_RS17125	COG0572	uridine kinase
AVL55_RS17130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVL55_RS17145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVL55_RS17165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVL55_RS17165	COG0517	IMP dehydrogenase activity
AVL55_RS17170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL55_RS17190	COG0189	ligase activity
AVL55_RS17200	COG4067	protein conserved in archaea
AVL55_RS17200	COG0189	ligase activity
AVL55_RS17215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVL55_RS17240	COG0583	DNA-binding transcription factor activity
AVL55_RS17270	COG0438	transferase activity, transferring glycosyl groups
AVL55_RS17270	COG1216	Glycosyl transferase, family 2
AVL55_RS17280	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVL55_RS17290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVL55_RS17365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVL55_RS17415	COG1404	Belongs to the peptidase S8 family
AVL55_RS17490	COG0202	RNA polymerase activity
AVL55_RS17515	COG0201	protein transport
AVL55_RS17535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVL55_RS17580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL55_RS17585	COG0557	exoribonuclease II activity
AVL55_RS17620	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AVL55_RS17640	COG2234	aminopeptidase activity
AVL55_RS17650	COG4251	negative regulation of phosphorylation
AVL55_RS17660	COG1271	oxidase subunit
AVL55_RS17665	COG1294	oxidase, subunit
AVL55_RS17670	COG1522	sequence-specific DNA binding
AVL55_RS17680	COG1278	Cold shock
AVL55_RS17685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL55_RS17695	COG2226	methyltransferase
AVL55_RS17705	COG0339	signal peptide processing
AVL55_RS17710	COG2201	protein-glutamate methylesterase activity
AVL55_RS17725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL55_RS17730	COG0243	molybdopterin cofactor binding
AVL55_RS17745	COG4946	Tricorn protease homolog
AVL55_RS17745	COG1506	peptidase
AVL55_RS17745	COG0823	Involved in the tonB-independent uptake of proteins
AVL55_RS17790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL55_RS17800	COG2197	response regulator
AVL55_RS17830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVL55_RS17835	COG1278	Cold shock
AVL55_RS17845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL55_RS17850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVL55_RS17865	COG0281	malic enzyme
AVL55_RS17875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVL55_RS17905	COG0456	acetyltransferase
AVL55_RS17915	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL55_RS17920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL55_RS17925	COG2177	Part of the ABC transporter FtsEX involved in
AVL55_RS17930	COG2884	Cell division ATP-binding protein ftsE
AVL55_RS17935	COG0552	protein localization to endoplasmic reticulum
AVL55_RS17945	COG0742	ribosomal rna small subunit methyltransferase
AVL55_RS17955	COG2095	MarC family integral membrane protein
AVL55_RS17975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL55_RS17980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL55_RS17985	COG0617	tRNA 3'-terminal CCA addition
AVL55_RS17990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVL55_RS18005	COG0076	glutamate decarboxylase activity
AVL55_RS18020	COG0842	Transport permease protein
AVL55_RS18025	COG1131	(ABC) transporter
AVL55_RS18030	COG0745	RESPONSE REGULATOR receiver
AVL55_RS18035	COG2205	protein histidine kinase activity
AVL55_RS18045	COG1253	flavin adenine dinucleotide binding
AVL55_RS18050	COG0701	Predicted permease
AVL55_RS18055	COG1966	Carbon starvation protein
AVL55_RS18105	COG0848	biopolymer transport protein
AVL55_RS18115	COG0811	peptide transport
AVL55_RS18135	COG3128	pkhd-type hydroxylase
AVL55_RS18140	COG4774	siderophore transport
AVL55_RS18175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVL55_RS18185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVL55_RS18220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVL55_RS18225	COG0049	tRNA binding
AVL55_RS18230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVL55_RS18235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVL55_RS18240	COG0085	RNA polymerase activity
AVL55_RS18245	COG0222	ribosome binding
AVL55_RS18250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVL55_RS18255	COG0081	regulation of translation
AVL55_RS18260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVL55_RS18275	COG0250	Participates in transcription elongation, termination and antitermination
AVL55_RS18280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL55_RS18290	COG1132	(ABC) transporter
AVL55_RS18295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVL55_RS18300	COG3590	peptidase
AVL55_RS18315	COG0513	Belongs to the DEAD box helicase family
AVL55_RS18325	COG0418	dihydroorotase activity
AVL55_RS18330	COG3040	lipid binding
AVL55_RS18335	COG4989	oxidoreductase activity
AVL55_RS18340	COG0346	lactoylglutathione lyase activity
AVL55_RS18345	COG0668	transmembrane transport
AVL55_RS18365	COG0302	gtp cyclohydrolase
AVL55_RS18375	COG2957	Belongs to the agmatine deiminase family
AVL55_RS18380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL55_RS18390	COG1201	RNA secondary structure unwinding
AVL55_RS18395	COG2311	Membrane
AVL55_RS18410	COG1793	dna ligase
AVL55_RS18415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVL55_RS18420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL55_RS18435	COG0625	glutathione transferase activity
AVL55_RS18440	COG0625	glutathione transferase activity
AVL55_RS18450	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AVL55_RS18465	COG1012	belongs to the aldehyde dehydrogenase family
AVL55_RS18470	COG0028	Belongs to the TPP enzyme family
AVL55_RS18485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVL55_RS18490	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AVL55_RS18495	COG0330	HflC and HflK could
AVL55_RS18500	COG0330	HflC and HflK could
AVL55_RS18505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVL55_RS18510	COG1923	regulation of RNA biosynthetic process
AVL55_RS18515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVL55_RS18530	COG0802	atpase or kinase
AVL55_RS18535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVL55_RS18535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVL55_RS18540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVL55_RS18560	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AVL55_RS18565	COG0735	belongs to the Fur family
AVL55_RS18585	COG0305	Participates in initiation and elongation during chromosome replication
AVL55_RS18610	COG2258	MOSC domain
AVL55_RS18680	COG0840	transmembrane signaling receptor activity
AVL55_RS18685	COG5002	protein histidine kinase activity
AVL55_RS18690	COG0840	transmembrane signaling receptor activity
AVL55_RS18695	COG2855	membrane
AVL55_RS18705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVL55_RS18710	COG4988	ABC transporter
AVL55_RS18715	COG4890	Cyd operon protein YbgT
AVL55_RS18720	COG1294	oxidase, subunit
AVL55_RS18755	COG4319	ketosteroid isomerase
AVL55_RS18760	COG1469	GTP cyclohydrolase I activity
AVL55_RS18800	COG3237	CsbD-like
AVL55_RS18820	COG0596	Alpha beta hydrolase
AVL55_RS18820	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL55_RS18845	COG3038	cytochrome b561
AVL55_RS18855	COG1252	NADH dehydrogenase
AVL55_RS18860	COG4206	TonB-dependent receptor
AVL55_RS18870	COG0583	DNA-binding transcription factor activity
AVL55_RS18875	COG2067	long-chain fatty acid transport protein
AVL55_RS18880	COG2130	NADP-dependent
AVL55_RS18885	COG5001	Diguanylate cyclase
AVL55_RS18885	COG3706	GGDEF domain
AVL55_RS18885	COG4251	negative regulation of phosphorylation
AVL55_RS18885	COG2203	Gaf domain
AVL55_RS18890	COG0784	Response regulator, receiver
AVL55_RS18890	COG2205	protein histidine kinase activity
AVL55_RS18900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL55_RS18915	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVL55_RS18925	COG0514	ATP-dependent DNA helicase (RecQ)
AVL55_RS18930	COG0732	type I restriction modification DNA specificity domain
AVL55_RS18935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AVL55_RS18955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVL55_RS18960	COG1349	DNA-binding transcription factor activity
AVL55_RS18965	COG0673	inositol 2-dehydrogenase activity
AVL55_RS18975	COG2203	Gaf domain
AVL55_RS18975	COG2199	diguanylate cyclase activity
AVL55_RS18980	COG0697	spore germination
AVL55_RS18985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVL55_RS18990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AVL55_RS18995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVL55_RS19000	COG1166	arginine decarboxylase activity
AVL55_RS19010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVL55_RS19090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL55_RS19100	COG0109	protoheme IX farnesyltransferase activity
AVL55_RS19110	COG1845	cytochrome c oxidase, subunit III
AVL55_RS19120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL55_RS19155	COG3030	protein affecting phage T7 exclusion by the F plasmid
AVL55_RS19160	COG1324	tolerance protein
AVL55_RS19165	COG4232	protein-disulfide reductase activity
AVL55_RS19170	COG0739	heme binding
AVL55_RS19175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVL55_RS19180	COG0511	ligase activity, forming carbon-carbon bonds
AVL55_RS19185	COG0439	Biotin carboxylase
AVL55_RS19230	COG0154	amidase activity
AVL55_RS19245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL55_RS19250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AVL55_RS19265	COG0151	Belongs to the GarS family
AVL55_RS19280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL55_RS19285	COG3954	Phosphoribulokinase
AVL55_RS19310	COG1501	Belongs to the glycosyl hydrolase 31 family
AVL55_RS19315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVL55_RS19320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVL55_RS19330	COG3031	protein transport across the cell outer membrane
AVL55_RS19340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL55_RS19345	COG1459	type II secretion system
AVL55_RS19350	COG2165	general secretion pathway protein
AVL55_RS19355	COG2165	general secretion pathway protein
AVL55_RS19360	COG2165	general secretion pathway protein
AVL55_RS19365	COG4795	General secretion pathway protein
AVL55_RS19380	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AVL55_RS19400	COG1012	belongs to the aldehyde dehydrogenase family
AVL55_RS19410	COG1011	Hydrolase
AVL55_RS19415	COG0494	nUDIX hydrolase
AVL55_RS19420	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVL55_RS19430	COG2943	transferase activity, transferring hexosyl groups
AVL55_RS19435	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AVL55_RS19445	COG3089	Belongs to the UPF0270 family
AVL55_RS19450	COG0429	hydrolase of the alpha beta-hydrolase fold
AVL55_RS19460	COG0488	(ABC) transporter
AVL55_RS19485	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL55_RS19495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL55_RS19500	COG2183	response to ionizing radiation
AVL55_RS19520	COG0596	Alpha beta hydrolase
AVL55_RS19525	COG1040	competence protein
AVL55_RS19545	COG1794	racemase activity, acting on amino acids and derivatives
AVL55_RS19555	COG0534	Mate efflux family protein
AVL55_RS19570	COG1999	signal sequence binding
AVL55_RS19575	COG0109	protoheme IX farnesyltransferase activity
AVL55_RS19580	COG1612	heme a metabolic process
AVL55_RS19600	COG1845	cytochrome c oxidase, subunit III
AVL55_RS19605	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVL55_RS19610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL55_RS19615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL55_RS19615	COG1565	acr, cog1565
AVL55_RS19640	COG0129	dihydroxy-acid dehydratase activity
AVL55_RS19645	COG2860	membrane
AVL55_RS19650	COG0606	chelatase, subunit chli
AVL55_RS19655	COG0583	DNA-binding transcription factor activity
AVL55_RS19665	COG2814	Major facilitator Superfamily
AVL55_RS19675	COG0729	surface antigen
AVL55_RS19680	COG2911	Protein conserved in bacteria
AVL55_RS19705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL55_RS19715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVL55_RS19735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL55_RS19760	COG1228	amidohydrolase
AVL55_RS19780	COG0425	Belongs to the sulfur carrier protein TusA family
AVL55_RS19795	COG1561	YicC-like family, N-terminal region
AVL55_RS19865	COG5433	transposase activity
AVL55_RS19885	COG0789	Transcriptional regulator
AVL55_RS19935	COG2211	Major facilitator Superfamily
AVL55_RS19940	COG1609	Transcriptional regulator
AVL55_RS19960	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVL55_RS19960	COG2199	diguanylate cyclase activity
AVL55_RS19990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVL55_RS20010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVL55_RS20015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVL55_RS20035	COG1475	DNA binding
AVL55_RS20040	COG1192	Involved in chromosome partitioning
AVL55_RS20065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL55_RS20070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVL55_RS20080	COG0706	membrane insertase activity
AVL55_RS20085	COG0594	ribonuclease P activity
AVL55_RS20090	COG0230	Belongs to the bacterial ribosomal protein bL34 family