locus-tag	class	description
FJN15_RS00045	COG2234	aminopeptidase activity
FJN15_RS00050	COG0463	Glycosyl transferase, family 2
FJN15_RS00060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FJN15_RS00085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJN15_RS00115	COG3642	lipopolysaccharide core region biosynthetic process
FJN15_RS00120	COG0859	PFAM glycosyl transferase family 9
FJN15_RS00150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FJN15_RS00165	COG3161	chorismate lyase activity
FJN15_RS00170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FJN15_RS00190	COG0210	DNA helicase
FJN15_RS00220	COG3550	peptidyl-serine autophosphorylation
FJN15_RS00225	COG1396	sequence-specific DNA binding
FJN15_RS00230	COG1757	Na H antiporter
FJN15_RS00245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FJN15_RS00290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS00295	COG0842	Transport permease protein
FJN15_RS00295	COG1129	ABC transporter
FJN15_RS00300	COG0842	Transport permease protein
FJN15_RS00310	COG4771	TonB-dependent receptor
FJN15_RS00325	COG0583	DNA-binding transcription factor activity
FJN15_RS00335	COG3106	COG3106 Predicted ATPase
FJN15_RS00350	COG2184	nucleotidyltransferase activity
FJN15_RS00355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FJN15_RS00370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FJN15_RS00375	COG0352	thiamine-phosphate diphosphorylase activity
FJN15_RS00385	COG3071	HemY protein
FJN15_RS00390	COG2959	enzyme of heme biosynthesis
FJN15_RS00400	COG0181	hydroxymethylbilane synthase activity
FJN15_RS00415	COG0194	GDP metabolic process
FJN15_RS00425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FJN15_RS00435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJN15_RS00440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FJN15_RS00450	COG0678	peroxiredoxin activity
FJN15_RS00465	COG1178	ABC-type Fe3 transport system permease component
FJN15_RS00470	COG3842	ATPase activity
FJN15_RS00475	COG0668	transmembrane transport
FJN15_RS00480	COG2081	HI0933 family
FJN15_RS00490	COG2200	EAL domain
FJN15_RS00495	COG0583	DNA-binding transcription factor activity
FJN15_RS00520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS00535	COG0427	acetyl-CoA hydrolase
FJN15_RS00540	COG0123	including yeast histone deacetylase and acetoin utilization protein
FJN15_RS00555	COG0840	transmembrane signaling receptor activity
FJN15_RS00565	COG3064	Membrane
FJN15_RS00575	COG5002	protein histidine kinase activity
FJN15_RS00575	COG5001	Diguanylate cyclase
FJN15_RS00590	COG0514	ATP-dependent DNA helicase (RecQ)
FJN15_RS00595	COG2239	Acts as a magnesium transporter
FJN15_RS00600	COG2962	Rard protein
FJN15_RS00610	COG0210	DNA helicase
FJN15_RS00620	COG1011	Hydrolase
FJN15_RS00625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FJN15_RS00635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FJN15_RS00640	COG0019	diaminopimelate decarboxylase activity
FJN15_RS00670	COG0163	prenyltransferase activity
FJN15_RS00675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FJN15_RS00685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FJN15_RS00705	COG1077	Cell shape determining protein MreB Mrl
FJN15_RS00720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJN15_RS00725	COG2814	Major facilitator Superfamily
FJN15_RS00730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJN15_RS00755	COG1085	galactose-1-phosphate uridylyltransferase
FJN15_RS00760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FJN15_RS00770	COG0629	single-stranded DNA binding
FJN15_RS00795	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS00820	COG1349	DNA-binding transcription factor activity
FJN15_RS00865	COG3267	Type II secretory pathway component ExeA
FJN15_RS00865	COG3409	Peptidoglycan-binding domain 1 protein
FJN15_RS00875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJN15_RS00880	COG1459	type II secretion system
FJN15_RS00890	COG2165	general secretion pathway protein
FJN15_RS00895	COG2165	general secretion pathway protein
FJN15_RS00900	COG2165	general secretion pathway protein
FJN15_RS00925	COG1077	Cell shape determining protein MreB Mrl
FJN15_RS00930	COG1792	Involved in formation and maintenance of cell shape
FJN15_RS00935	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FJN15_RS00945	COG1530	ribonuclease E activity
FJN15_RS00955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJN15_RS00960	COG0312	modulator of DNA gyrase
FJN15_RS00965	COG3028	Belongs to the UPF0307 family
FJN15_RS00970	COG0312	modulator of DNA gyrase
FJN15_RS00985	COG0745	RESPONSE REGULATOR receiver
FJN15_RS00990	COG4191	Histidine kinase
FJN15_RS00990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJN15_RS00995	COG0297	glycogen (starch) synthase activity
FJN15_RS01005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJN15_RS01010	COG0596	Alpha beta hydrolase
FJN15_RS01050	COG2814	Major facilitator Superfamily
FJN15_RS01060	COG0745	RESPONSE REGULATOR receiver
FJN15_RS01065	COG2198	Histidine kinase
FJN15_RS01065	COG0643	Histidine kinase
FJN15_RS01070	COG0835	chemotaxis
FJN15_RS01085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FJN15_RS01100	COG0745	RESPONSE REGULATOR receiver
FJN15_RS01105	COG2198	Histidine kinase
FJN15_RS01105	COG0643	Histidine kinase
FJN15_RS01110	COG0835	chemotaxis
FJN15_RS01130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FJN15_RS01205	COG0673	inositol 2-dehydrogenase activity
FJN15_RS01215	COG2211	Major facilitator Superfamily
FJN15_RS01220	COG1082	Xylose isomerase domain protein TIM barrel
FJN15_RS01240	COG1454	alcohol dehydrogenase
FJN15_RS01270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJN15_RS01290	COG0089	rRNA binding
FJN15_RS01300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FJN15_RS01310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FJN15_RS01325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FJN15_RS01330	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS01340	COG1519	Transferase
FJN15_RS01360	COG0840	transmembrane signaling receptor activity
FJN15_RS01375	COG0788	formyltetrahydrofolate deformylase activity
FJN15_RS01385	COG1643	Atp-dependent helicase
FJN15_RS01390	COG2951	lytic endotransglycosylase activity
FJN15_RS01395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FJN15_RS01405	COG2354	Protein conserved in bacteria
FJN15_RS01430	COG0004	ammonium transporteR
FJN15_RS01435	COG0405	Gamma-glutamyltransferase
FJN15_RS01440	COG2837	iron assimilation
FJN15_RS01455	COG0540	Belongs to the ATCase OTCase family
FJN15_RS01480	COG0784	Response regulator, receiver
FJN15_RS01480	COG5002	protein histidine kinase activity
FJN15_RS01480	COG2205	protein histidine kinase activity
FJN15_RS01495	COG5001	Diguanylate cyclase
FJN15_RS01495	COG3300	MHYT domain
FJN15_RS01505	COG1012	belongs to the aldehyde dehydrogenase family
FJN15_RS01515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJN15_RS01530	COG0180	Tryptophanyl-tRNA synthetase
FJN15_RS01535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FJN15_RS01555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FJN15_RS01565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FJN15_RS01600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FJN15_RS01605	COG0281	malic enzyme
FJN15_RS01615	COG0625	glutathione transferase activity
FJN15_RS01625	COG0753	catalase activity
FJN15_RS01650	COG3300	MHYT domain
FJN15_RS01650	COG5001	Diguanylate cyclase
FJN15_RS01655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FJN15_RS01655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJN15_RS01665	COG0137	argininosuccinate synthase activity
FJN15_RS01685	COG1803	Methylglyoxal synthase
FJN15_RS01695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FJN15_RS01710	COG0745	RESPONSE REGULATOR receiver
FJN15_RS01715	COG2205	protein histidine kinase activity
FJN15_RS01720	COG2267	carboxylic ester hydrolase activity
FJN15_RS01725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FJN15_RS01735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJN15_RS01745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FJN15_RS01750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FJN15_RS01755	COG4942	peptidase
FJN15_RS01760	COG2861	carbohydrate metabolic process
FJN15_RS01785	COG1162	GTPase activity
FJN15_RS01790	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FJN15_RS01815	COG0457	Tetratricopeptide repeat
FJN15_RS01830	COG0028	Belongs to the TPP enzyme family
FJN15_RS01850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJN15_RS01855	COG0805	protein transport
FJN15_RS01865	COG0084	hydrolase, TatD family'
FJN15_RS01870	COG5001	Diguanylate cyclase
FJN15_RS01870	COG2203	Gaf domain
FJN15_RS01870	COG3706	GGDEF domain
FJN15_RS01870	COG4251	negative regulation of phosphorylation
FJN15_RS01880	COG0248	Ppx GppA phosphatase
FJN15_RS01885	COG0513	Belongs to the DEAD box helicase family
FJN15_RS01890	COG3118	belongs to the thioredoxin family
FJN15_RS01895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FJN15_RS01900	COG1473	amidohydrolase
FJN15_RS01905	COG0784	Response regulator, receiver
FJN15_RS01905	COG5002	protein histidine kinase activity
FJN15_RS01910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FJN15_RS01915	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FJN15_RS01920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FJN15_RS01935	COG0783	Belongs to the Dps family
FJN15_RS01940	COG2133	pyrroloquinoline quinone binding
FJN15_RS01945	COG1506	peptidase
FJN15_RS01945	COG0823	Involved in the tonB-independent uptake of proteins
FJN15_RS01945	COG4946	Tricorn protease homolog
FJN15_RS01955	COG3118	belongs to the thioredoxin family
FJN15_RS01970	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FJN15_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
FJN15_RS02000	COG1757	Na H antiporter
FJN15_RS02015	COG3876	Protein conserved in bacteria
FJN15_RS02020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FJN15_RS02030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FJN15_RS02040	COG0346	lactoylglutathione lyase activity
FJN15_RS02065	COG2824	Alkylphosphonate utilization operon protein PhnA
FJN15_RS02070	COG0454	-acetyltransferase
FJN15_RS02210	COG0183	Belongs to the thiolase family
FJN15_RS02215	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJN15_RS02215	COG1024	Enoyl-CoA hydratase
FJN15_RS02225	COG0006	proline dipeptidase activity
FJN15_RS02235	COG0142	geranyltranstransferase activity
FJN15_RS02265	COG1388	LysM domain
FJN15_RS02265	COG4942	peptidase
FJN15_RS02270	COG1238	metal cluster binding
FJN15_RS02280	COG0585	pseudouridine synthase activity
FJN15_RS02285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FJN15_RS02295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FJN15_RS02305	COG0840	transmembrane signaling receptor activity
FJN15_RS02340	COG0494	nUDIX hydrolase
FJN15_RS02345	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FJN15_RS02350	COG0730	response to heat
FJN15_RS02355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FJN15_RS02360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FJN15_RS02365	COG2201	protein-glutamate methylesterase activity
FJN15_RS02395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FJN15_RS02410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FJN15_RS02420	COG1648	precorrin-2 dehydrogenase activity
FJN15_RS02420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJN15_RS02425	COG0513	Belongs to the DEAD box helicase family
FJN15_RS02440	COG1538	Outer membrane efflux protein
FJN15_RS02445	COG0494	nUDIX hydrolase
FJN15_RS02455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FJN15_RS02460	COG3150	esterase
FJN15_RS02465	COG0187	DNA topoisomerase II activity
FJN15_RS02475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJN15_RS02495	COG1509	lysine 2,3-aminomutase activity
FJN15_RS02500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJN15_RS02505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FJN15_RS02520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJN15_RS02525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJN15_RS02540	COG0271	Belongs to the BolA IbaG family
FJN15_RS02555	COG3707	response regulator
FJN15_RS02565	COG0659	secondary active sulfate transmembrane transporter activity
FJN15_RS02570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJN15_RS02580	COG0243	molybdopterin cofactor binding
FJN15_RS02585	COG1648	precorrin-2 dehydrogenase activity
FJN15_RS02585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJN15_RS02590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJN15_RS02600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FJN15_RS02600	COG1116	anion transmembrane transporter activity
FJN15_RS02610	COG1116	anion transmembrane transporter activity
FJN15_RS02625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FJN15_RS02630	COG4206	TonB-dependent receptor
FJN15_RS02635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FJN15_RS02640	COG0348	domain, Protein
FJN15_RS02655	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS02670	COG4948	Mandelate Racemase Muconate Lactonizing
FJN15_RS02685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS02690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJN15_RS02715	COG0358	DNA primase activity
FJN15_RS02720	COG1610	YqeY-like protein
FJN15_RS02740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FJN15_RS02745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FJN15_RS02760	COG0537	adenosine 5'-monophosphoramidase activity
FJN15_RS02775	COG3135	benzoate transporter
FJN15_RS02780	COG1396	sequence-specific DNA binding
FJN15_RS02785	COG2974	May be involved in recombination
FJN15_RS02790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJN15_RS02790	COG4191	Histidine kinase
FJN15_RS02795	COG0745	RESPONSE REGULATOR receiver
FJN15_RS02800	COG5002	protein histidine kinase activity
FJN15_RS02825	COG0811	peptide transport
FJN15_RS02830	COG0811	peptide transport
FJN15_RS02835	COG0848	biopolymer transport protein
FJN15_RS02840	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FJN15_RS02850	COG3437	response regulator, receiver
FJN15_RS02870	COG2133	pyrroloquinoline quinone binding
FJN15_RS02880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJN15_RS02910	COG0527	aspartate kinase activity
FJN15_RS02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FJN15_RS02925	COG2967	ApaG domain
FJN15_RS02935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FJN15_RS02940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJN15_RS02945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FJN15_RS02950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FJN15_RS02960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FJN15_RS02980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FJN15_RS02995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FJN15_RS03000	COG3956	TIGRFAM MazG family protein
FJN15_RS03025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FJN15_RS03030	COG0723	plastoquinol--plastocyanin reductase activity
FJN15_RS03035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJN15_RS03040	COG2857	Cytochrome c1
FJN15_RS03045	COG0625	glutathione transferase activity
FJN15_RS03050	COG2969	positive regulation of protein catabolic process
FJN15_RS03065	COG0745	RESPONSE REGULATOR receiver
FJN15_RS03070	COG2239	Acts as a magnesium transporter
FJN15_RS03075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FJN15_RS03095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJN15_RS03100	COG1137	ATPase activity
FJN15_RS03105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FJN15_RS03115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FJN15_RS03130	COG1127	ABC transporter
FJN15_RS03135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FJN15_RS03140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FJN15_RS03145	COG2854	intermembrane phospholipid transfer
FJN15_RS03155	COG5007	Belongs to the BolA IbaG family
FJN15_RS03165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJN15_RS03170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJN15_RS03180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FJN15_RS03215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJN15_RS03230	COG4771	TonB-dependent receptor
FJN15_RS03235	COG0697	spore germination
FJN15_RS03240	COG0784	Response regulator, receiver
FJN15_RS03240	COG2205	protein histidine kinase activity
FJN15_RS03265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FJN15_RS03275	COG0126	phosphoglycerate kinase activity
FJN15_RS03280	COG3588	fructose-bisphosphate aldolase
FJN15_RS03290	COG4946	Tricorn protease homolog
FJN15_RS03290	COG1506	peptidase
FJN15_RS03290	COG0823	Involved in the tonB-independent uptake of proteins
FJN15_RS03295	COG0248	Ppx GppA phosphatase
FJN15_RS03300	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FJN15_RS03310	COG0573	inorganic phosphate transmembrane transporter activity
FJN15_RS03320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FJN15_RS03330	COG0306	phosphate transporter
FJN15_RS03340	COG0583	DNA-binding transcription factor activity
FJN15_RS03350	COG1272	protein, Hemolysin III
FJN15_RS03355	COG1846	Transcriptional regulator
FJN15_RS03360	COG1764	response to oxidative stress
FJN15_RS03375	COG1739	Uncharacterized protein family UPF0029
FJN15_RS03395	COG0583	DNA-binding transcription factor activity
FJN15_RS03400	COG4989	oxidoreductase activity
FJN15_RS03415	COG0420	3'-5' exonuclease activity
FJN15_RS03420	COG0419	ATPase involved in DNA repair
FJN15_RS03430	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FJN15_RS03455	COG2188	Transcriptional regulator
FJN15_RS03465	COG2986	histidine ammonia-lyase
FJN15_RS03490	COG0488	(ABC) transporter
FJN15_RS03515	COG0668	transmembrane transport
FJN15_RS03540	COG0582	viral genome integration into host DNA
FJN15_RS03590	COG1203	CRISPR-associated helicase, Cas3
FJN15_RS03645	COG1346	cytolysis
FJN15_RS03675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJN15_RS03685	COG0513	Belongs to the DEAD box helicase family
FJN15_RS03695	COG3409	Peptidoglycan-binding domain 1 protein
FJN15_RS03695	COG3267	Type II secretory pathway component ExeA
FJN15_RS03710	COG0066	3-isopropylmalate dehydratase activity
FJN15_RS03720	COG0473	3-isopropylmalate dehydrogenase activity
FJN15_RS03725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJN15_RS03750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FJN15_RS03765	COG4555	ABC transporter
FJN15_RS03770	COG1668	transmembrane transport
FJN15_RS03780	COG0745	RESPONSE REGULATOR receiver
FJN15_RS03810	COG4133	protoheme IX ABC transporter activity
FJN15_RS03815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJN15_RS03820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJN15_RS03825	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJN15_RS03835	COG1138	Cytochrome C-type biogenesis protein
FJN15_RS03840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJN15_RS03855	COG2853	Lipoprotein
FJN15_RS03860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FJN15_RS03900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJN15_RS03915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FJN15_RS03920	COG1555	photosystem II stabilization
FJN15_RS03920	COG1596	polysaccharide export
FJN15_RS03925	COG0473	3-isopropylmalate dehydrogenase activity
FJN15_RS03940	COG1611	Belongs to the LOG family
FJN15_RS03950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FJN15_RS03950	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FJN15_RS04005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FJN15_RS04010	COG0024	Methionine aminopeptidase
FJN15_RS04015	COG0052	Belongs to the universal ribosomal protein uS2 family
FJN15_RS04025	COG0528	UMP kinase activity
FJN15_RS04040	COG0575	Belongs to the CDS family
FJN15_RS04065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJN15_RS04085	COG0587	DNA-directed DNA polymerase activity
FJN15_RS04090	COG0825	malonyl-CoA metabolic process
FJN15_RS04095	COG0037	tRNA processing
FJN15_RS04125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJN15_RS04125	COG0047	phosphoribosylformylglycinamidine synthase activity
FJN15_RS04130	COG2840	Smr protein MutS2
FJN15_RS04155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS04160	COG2197	response regulator
FJN15_RS04200	COG0784	Response regulator, receiver
FJN15_RS04200	COG0835	chemotaxis
FJN15_RS04205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJN15_RS04210	COG1815	bacterial-type flagellum-dependent cell motility
FJN15_RS04225	COG1749	Flagellar hook protein flgE
FJN15_RS04230	COG4787	bacterial-type flagellum-dependent cell motility
FJN15_RS04250	COG3951	Flagellar rod assembly protein muramidase FlgJ
FJN15_RS04250	COG1705	Flagellar rod assembly protein muramidase FlgJ
FJN15_RS04255	COG1256	bacterial-type flagellum assembly
FJN15_RS04280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJN15_RS04285	COG1334	flagellar protein FlaG
FJN15_RS04290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FJN15_RS04310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJN15_RS04315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJN15_RS04330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FJN15_RS04355	COG2089	acid synthase
FJN15_RS04370	COG1083	cytidylyl-transferase
FJN15_RS04390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJN15_RS04405	COG2089	acid synthase
FJN15_RS04415	COG1083	cytidylyl-transferase
FJN15_RS04420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJN15_RS04425	COG1086	Polysaccharide biosynthesis protein
FJN15_RS04430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJN15_RS04455	COG1677	Flagellar hook-basal body complex protein FliE
FJN15_RS04460	COG1766	The M ring may be actively involved in energy transduction
FJN15_RS04465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJN15_RS04515	COG1987	bacterial-type flagellum assembly
FJN15_RS04530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJN15_RS04555	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FJN15_RS04560	COG2198	Histidine kinase
FJN15_RS04560	COG0784	Response regulator, receiver
FJN15_RS04560	COG0643	Histidine kinase
FJN15_RS04570	COG1192	Involved in chromosome partitioning
FJN15_RS04580	COG0835	chemotaxis
FJN15_RS04595	COG1410	methionine synthase
FJN15_RS04595	COG0646	methionine synthase
FJN15_RS04600	COG0646	methionine synthase
FJN15_RS04600	COG1410	methionine synthase
FJN15_RS04610	COG3123	guanosine phosphorylase activity
FJN15_RS04620	COG0583	DNA-binding transcription factor activity
FJN15_RS04625	COG0583	DNA-binding transcription factor activity
FJN15_RS04635	COG0659	secondary active sulfate transmembrane transporter activity
FJN15_RS04650	COG3590	peptidase
FJN15_RS04660	COG2137	regulation of response to DNA damage stimulus
FJN15_RS04665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJN15_RS04695	COG5016	pyruvate
FJN15_RS04695	COG0511	ligase activity, forming carbon-carbon bonds
FJN15_RS04700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FJN15_RS04705	COG4172	Belongs to the ABC transporter superfamily
FJN15_RS04715	COG4171	peptide transport system, permease
FJN15_RS04720	COG4168	peptide transport system, permease
FJN15_RS04725	COG0747	negative chemotaxis
FJN15_RS04730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FJN15_RS04735	COG1842	Phage shock protein A
FJN15_RS04765	COG0625	glutathione transferase activity
FJN15_RS04770	COG1522	sequence-specific DNA binding
FJN15_RS04835	COG0811	peptide transport
FJN15_RS04840	COG0811	peptide transport
FJN15_RS04845	COG0848	biopolymer transport protein
FJN15_RS04860	COG1444	tRNA N-acetyltransferase activity
FJN15_RS04900	COG0456	acetyltransferase
FJN15_RS04915	COG0583	DNA-binding transcription factor activity
FJN15_RS04920	COG2814	Major facilitator Superfamily
FJN15_RS04925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJN15_RS04930	COG0656	L-ascorbic acid biosynthetic process
FJN15_RS04940	COG3706	GGDEF domain
FJN15_RS04970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FJN15_RS05015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJN15_RS05020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FJN15_RS05025	COG0564	pseudouridine synthase activity
FJN15_RS05035	COG0612	Peptidase, M16
FJN15_RS05040	COG2918	glutathione biosynthetic process
FJN15_RS05060	COG2840	Smr protein MutS2
FJN15_RS05065	COG2890	protein-(glutamine-N5) methyltransferase activity
FJN15_RS05080	COG2719	SpoVR family
FJN15_RS05085	COG2718	Belongs to the UPF0229 family
FJN15_RS05090	COG2766	serine protein kinase
FJN15_RS05095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FJN15_RS05100	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FJN15_RS05105	COG4771	TonB-dependent receptor
FJN15_RS05130	COG0450	alkyl hydroperoxide reductase
FJN15_RS05140	COG2885	chlorophyll binding
FJN15_RS05145	COG0584	glycerophosphoryl diester phosphodiesterase
FJN15_RS05150	COG0346	lactoylglutathione lyase activity
FJN15_RS05155	COG1278	Cold shock
FJN15_RS05175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FJN15_RS05180	COG4660	Part of a membrane complex involved in electron transport
FJN15_RS05185	COG4659	FMN binding
FJN15_RS05190	COG4658	electron transport chain
FJN15_RS05195	COG4656	Part of a membrane complex involved in electron transport
FJN15_RS05200	COG2878	Part of a membrane complex involved in electron transport
FJN15_RS05205	COG4657	Part of a membrane complex involved in electron transport
FJN15_RS05220	COG0534	Mate efflux family protein
FJN15_RS05225	COG0556	nucleotide-excision repair
FJN15_RS05240	COG0602	queuosine metabolic process
FJN15_RS05250	COG0367	asparagine synthase
FJN15_RS05275	COG0471	metal ion transport
FJN15_RS05275	COG3273	potassium ion transport
FJN15_RS05290	COG0529	Catalyzes the synthesis of activated sulfate
FJN15_RS05295	COG0175	sulfate reduction
FJN15_RS05300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS05305	COG3706	GGDEF domain
FJN15_RS05330	COG2304	oxidoreductase activity
FJN15_RS05350	COG0714	Associated with various cellular activities
FJN15_RS05360	COG1024	Enoyl-CoA hydratase
FJN15_RS05360	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJN15_RS05375	COG1025	Belongs to the peptidase M16 family
FJN15_RS05380	COG2062	phosphohistidine phosphatase, SixA
FJN15_RS05390	COG4536	flavin adenine dinucleotide binding
FJN15_RS05395	COG4137	Cytochrome C assembly protein
FJN15_RS05400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FJN15_RS05445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS05450	COG1132	(ABC) transporter
FJN15_RS05465	COG0228	four-way junction DNA binding
FJN15_RS05470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FJN15_RS05475	COG0336	Belongs to the RNA methyltransferase TrmD family
FJN15_RS05480	COG0335	large ribosomal subunit rRNA binding
FJN15_RS05485	COG2860	membrane
FJN15_RS05495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FJN15_RS05500	COG1605	Chorismate mutase
FJN15_RS05500	COG0287	Prephenate dehydrogenase
FJN15_RS05505	COG0077	Prephenate dehydratase
FJN15_RS05505	COG1605	Chorismate mutase
FJN15_RS05510	COG0745	RESPONSE REGULATOR receiver
FJN15_RS05515	COG0023	Translation Initiation Factor
FJN15_RS05545	COG2205	protein histidine kinase activity
FJN15_RS05555	COG2204	response regulator
FJN15_RS05580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FJN15_RS05585	COG0494	nUDIX hydrolase
FJN15_RS05590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FJN15_RS05595	COG0632	four-way junction helicase activity
FJN15_RS05600	COG2255	four-way junction helicase activity
FJN15_RS05605	COG0824	Thioesterase
FJN15_RS05610	COG0811	peptide transport
FJN15_RS05625	COG0823	Involved in the tonB-independent uptake of proteins
FJN15_RS05630	COG2885	chlorophyll binding
FJN15_RS05635	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FJN15_RS05655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FJN15_RS05670	COG4667	esterase of the alpha-beta hydrolase superfamily
FJN15_RS05675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FJN15_RS05685	COG0784	Response regulator, receiver
FJN15_RS05685	COG2205	protein histidine kinase activity
FJN15_RS05700	COG0300	oxidoreductase activity
FJN15_RS05705	COG3038	cytochrome b561
FJN15_RS05735	COG0583	DNA-binding transcription factor activity
FJN15_RS05740	COG3321	synthase
FJN15_RS05740	COG0604	alcohol dehydrogenase
FJN15_RS05745	COG1451	nucleotide metabolic process
FJN15_RS05750	COG0517	IMP dehydrogenase activity
FJN15_RS05755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJN15_RS05765	COG1309	transcriptional regulator
FJN15_RS05770	COG4774	siderophore transport
FJN15_RS05795	COG3706	GGDEF domain
FJN15_RS05805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FJN15_RS05805	COG3008	intermembrane lipid transfer
FJN15_RS05810	COG2995	paraquat-inducible protein a
FJN15_RS05830	COG2207	Transcriptional regulator
FJN15_RS05835	COG0017	Asparaginyl-tRNA synthetase
FJN15_RS05850	COG0189	ligase activity
FJN15_RS05880	COG0156	8-amino-7-oxononanoate synthase activity
FJN15_RS05885	COG2226	methyltransferase
FJN15_RS05895	COG3340	Belongs to the peptidase S51 family
FJN15_RS05900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJN15_RS05905	COG4139	cobalamin transport
FJN15_RS05910	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FJN15_RS05915	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJN15_RS05930	COG5265	(ABC) transporter
FJN15_RS05935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FJN15_RS05945	COG0745	RESPONSE REGULATOR receiver
FJN15_RS05970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJN15_RS06010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJN15_RS06025	COG2755	lipolytic protein G-D-S-L family
FJN15_RS06030	COG4181	ATPase activity
FJN15_RS06035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FJN15_RS06040	COG1090	epimerase
FJN15_RS06045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FJN15_RS06050	COG0628	permease
FJN15_RS06075	COG2350	Protein conserved in bacteria
FJN15_RS06080	COG0159	tryptophan synthase activity
FJN15_RS06090	COG0135	phosphoribosylanthranilate isomerase activity
FJN15_RS06090	COG0134	indole-3-glycerol-phosphate synthase activity
FJN15_RS06095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJN15_RS06105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJN15_RS06110	COG0613	PHP domain protein
FJN15_RS06115	COG0009	L-threonylcarbamoyladenylate synthase
FJN15_RS06125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FJN15_RS06135	COG0656	L-ascorbic acid biosynthetic process
FJN15_RS06140	COG0110	maltose O-acetyltransferase activity
FJN15_RS06150	COG2733	membrane
FJN15_RS06170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS06175	COG0500	methyltransferase
FJN15_RS06180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJN15_RS06185	COG0497	DNA recombination
FJN15_RS06190	COG0783	Belongs to the Dps family
FJN15_RS06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FJN15_RS06200	COG1454	alcohol dehydrogenase
FJN15_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS06215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJN15_RS06220	COG2610	gluconate transmembrane transporter activity
FJN15_RS06235	COG2205	protein histidine kinase activity
FJN15_RS06235	COG0784	Response regulator, receiver
FJN15_RS06235	COG2198	Histidine kinase
FJN15_RS06250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJN15_RS06260	COG0484	heat shock protein binding
FJN15_RS06265	COG3909	cytochrome
FJN15_RS06285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FJN15_RS06290	COG0505	Belongs to the CarA family
FJN15_RS06295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FJN15_RS06300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJN15_RS06325	COG0857	belongs to the CobB CobQ family
FJN15_RS06325	COG0280	phosphate acetyltransferase
FJN15_RS06340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FJN15_RS06345	COG4535	Mg2 and Co2 transporter CorC
FJN15_RS06355	COG1702	phosphate starvation-inducible protein PhoH
FJN15_RS06365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJN15_RS06395	COG1607	acyl-coa hydrolase
FJN15_RS06400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FJN15_RS06415	COG1115	amino acid carrier protein
FJN15_RS06465	COG0012	GTP binding
FJN15_RS06480	COG1064	alcohol dehydrogenase
FJN15_RS06495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FJN15_RS06505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FJN15_RS06510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FJN15_RS06515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FJN15_RS06525	COG2890	protein-(glutamine-N5) methyltransferase activity
FJN15_RS06530	COG0784	Response regulator, receiver
FJN15_RS06530	COG3437	response regulator, receiver
FJN15_RS06540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FJN15_RS06550	COG0583	DNA-binding transcription factor activity
FJN15_RS06560	COG2363	Small membrane protein
FJN15_RS06575	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FJN15_RS06580	COG0515	serine threonine protein kinase
FJN15_RS06585	COG2116	formate transmembrane transporter activity
FJN15_RS06600	COG0714	Associated with various cellular activities
FJN15_RS06605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FJN15_RS06610	COG0033	Phosphoglucomutase
FJN15_RS06615	COG0058	SHG alpha-glucan phosphorylase activity
FJN15_RS06625	COG2988	succinylglutamate desuccinylase activity
FJN15_RS06660	COG1393	Belongs to the ArsC family
FJN15_RS06685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FJN15_RS06725	COG5001	Diguanylate cyclase
FJN15_RS06725	COG3300	MHYT domain
FJN15_RS06750	COG2249	NAD(P)H dehydrogenase (quinone) activity
FJN15_RS06770	COG1733	regulation of RNA biosynthetic process
FJN15_RS06775	COG5001	Diguanylate cyclase
FJN15_RS06775	COG5002	protein histidine kinase activity
FJN15_RS06775	COG3447	MASE1 domain protein
FJN15_RS06785	COG0402	S-adenosylhomocysteine deaminase activity
FJN15_RS06790	COG2351	hydroxyisourate hydrolase activity
FJN15_RS06805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJN15_RS06815	COG1309	transcriptional regulator
FJN15_RS06830	COG2252	PERMEase
FJN15_RS06835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FJN15_RS06850	COG3706	GGDEF domain
FJN15_RS06850	COG5001	Diguanylate cyclase
FJN15_RS06850	COG4251	negative regulation of phosphorylation
FJN15_RS06850	COG2203	Gaf domain
FJN15_RS06855	COG2205	protein histidine kinase activity
FJN15_RS06855	COG0784	Response regulator, receiver
FJN15_RS06865	COG2233	PERMEase
FJN15_RS06880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJN15_RS06885	COG0730	response to heat
FJN15_RS06925	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS06930	COG3001	Fructosamine kinase
FJN15_RS06940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FJN15_RS06955	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FJN15_RS06955	COG0662	Cupin 2, conserved barrel domain protein
FJN15_RS06960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJN15_RS06970	COG1596	polysaccharide export
FJN15_RS06975	COG0489	protein tyrosine kinase activity
FJN15_RS06980	COG4464	protein tyrosine phosphatase activity
FJN15_RS07015	COG0297	glycogen (starch) synthase activity
FJN15_RS07035	COG1215	transferase activity, transferring glycosyl groups
FJN15_RS07045	COG0463	Glycosyl transferase, family 2
FJN15_RS07080	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS07090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FJN15_RS07090	COG2755	lipolytic protein G-D-S-L family
FJN15_RS07105	COG0072	phenylalanine-tRNA ligase activity
FJN15_RS07105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJN15_RS07130	COG1472	Belongs to the glycosyl hydrolase 3 family
FJN15_RS07135	COG2096	Adenosyltransferase
FJN15_RS07145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FJN15_RS07155	COG4591	ABC-type transport system involved in lipoprotein release permease component
FJN15_RS07180	COG0708	Exodeoxyribonuclease III
FJN15_RS07215	COG2814	Major facilitator Superfamily
FJN15_RS07250	COG4770	biotin carboxylase activity
FJN15_RS07255	COG1024	Enoyl-CoA hydratase
FJN15_RS07260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FJN15_RS07265	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS07270	COG0789	Transcriptional regulator
FJN15_RS07275	COG0183	Belongs to the thiolase family
FJN15_RS07290	COG3706	GGDEF domain
FJN15_RS07300	COG2925	Exonuclease
FJN15_RS07350	COG1643	Atp-dependent helicase
FJN15_RS07370	COG3321	synthase
FJN15_RS07370	COG0604	alcohol dehydrogenase
FJN15_RS07375	COG0328	RNA-DNA hybrid ribonuclease activity
FJN15_RS07380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FJN15_RS07410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FJN15_RS07415	COG1136	(ABC) transporter
FJN15_RS07420	COG4591	ABC-type transport system involved in lipoprotein release permease component
FJN15_RS07435	COG3724	N-succinylarginine dihydrolase activity
FJN15_RS07445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FJN15_RS07460	COG0746	molybdenum cofactor guanylyltransferase activity
FJN15_RS07465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FJN15_RS07470	COG0243	molybdopterin cofactor binding
FJN15_RS07480	COG0625	glutathione transferase activity
FJN15_RS07495	COG2153	protein acetylation
FJN15_RS07510	COG1530	ribonuclease E activity
FJN15_RS07530	COG1399	metal-binding, possibly nucleic acid-binding protein
FJN15_RS07540	COG0416	fatty acid biosynthetic process
FJN15_RS07545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJN15_RS07550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FJN15_RS07560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJN15_RS07565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJN15_RS07575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FJN15_RS07590	COG0084	hydrolase, TatD family'
FJN15_RS07600	COG0702	epimerase
FJN15_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS07630	COG0596	Alpha beta hydrolase
FJN15_RS07640	COG0183	Belongs to the thiolase family
FJN15_RS07645	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS07665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJN15_RS07675	COG0246	Mannitol dehydrogenase
FJN15_RS07700	COG0668	transmembrane transport
FJN15_RS07705	COG4771	TonB-dependent receptor
FJN15_RS07735	COG3437	response regulator, receiver
FJN15_RS07745	COG0195	Participates in both transcription termination and antitermination
FJN15_RS07760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FJN15_RS07775	COG3300	MHYT domain
FJN15_RS07775	COG5001	Diguanylate cyclase
FJN15_RS07780	COG1187	pseudouridine synthase activity
FJN15_RS07790	COG3153	acetyltransferase
FJN15_RS07790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJN15_RS07860	COG1032	radical SAM domain protein
FJN15_RS07875	COG4771	TonB-dependent receptor
FJN15_RS07880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJN15_RS07890	COG4134	Bacterial extracellular solute-binding protein
FJN15_RS07900	COG4136	ATPase activity
FJN15_RS07905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FJN15_RS07925	COG5001	Diguanylate cyclase
FJN15_RS07925	COG2203	Gaf domain
FJN15_RS07925	COG3706	GGDEF domain
FJN15_RS07925	COG4251	negative regulation of phosphorylation
FJN15_RS07945	COG0583	DNA-binding transcription factor activity
FJN15_RS07965	COG1131	(ABC) transporter
FJN15_RS07980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJN15_RS07985	COG0385	Bile acid
FJN15_RS08015	COG3311	Transcriptional regulator
FJN15_RS08045	COG0758	DNA mediated transformation
FJN15_RS08060	COG0582	viral genome integration into host DNA
FJN15_RS08070	COG1902	pentaerythritol trinitrate reductase activity
FJN15_RS08080	COG2867	negative regulation of translational initiation
FJN15_RS08085	COG2914	Belongs to the UPF0125 (RnfH) family
FJN15_RS08095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FJN15_RS08105	COG0457	Tetratricopeptide repeat
FJN15_RS08120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJN15_RS08120	COG0574	Belongs to the PEP-utilizing enzyme family
FJN15_RS08155	COG2850	peptidyl-arginine hydroxylation
FJN15_RS08165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJN15_RS08170	COG2915	High frequency lysogenization protein hflD homolog
FJN15_RS08175	COG0482	sulfurtransferase activity
FJN15_RS08180	COG1187	pseudouridine synthase activity
FJN15_RS08190	COG1278	Cold shock
FJN15_RS08195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FJN15_RS08200	COG0542	response to heat
FJN15_RS08205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJN15_RS08210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FJN15_RS08215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FJN15_RS08220	COG0492	ferredoxin-NADP+ reductase activity
FJN15_RS08230	COG3091	SprT-like family
FJN15_RS08235	COG0616	signal peptide processing
FJN15_RS08250	COG0778	Nitroreductase
FJN15_RS08260	COG0252	asparaginase activity
FJN15_RS08265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FJN15_RS08270	COG0321	lipoyl(octanoyl) transferase activity
FJN15_RS08275	COG2921	Belongs to the UPF0250 family
FJN15_RS08280	COG1686	Belongs to the peptidase S11 family
FJN15_RS08285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FJN15_RS08290	COG0772	Belongs to the SEDS family
FJN15_RS08295	COG0768	penicillin binding
FJN15_RS08300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FJN15_RS08305	COG0799	negative regulation of ribosome biogenesis
FJN15_RS08315	COG1466	dna polymerase III delta subunit
FJN15_RS08320	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FJN15_RS08325	COG0495	leucyl-tRNA aminoacylation
FJN15_RS08335	COG1067	ATP-dependent peptidase activity
FJN15_RS08340	COG0596	Alpha beta hydrolase
FJN15_RS08345	COG3706	GGDEF domain
FJN15_RS08355	COG1534	Rna-binding protein
FJN15_RS08360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FJN15_RS08365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJN15_RS08370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FJN15_RS08375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJN15_RS08380	COG0149	triose-phosphate isomerase activity
FJN15_RS08385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJN15_RS08415	COG1597	lipid kinase activity
FJN15_RS08415	COG1803	Methylglyoxal synthase
FJN15_RS08425	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS08430	COG0561	phosphatase activity
FJN15_RS08445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS08450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJN15_RS08455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FJN15_RS08470	COG1185	polyribonucleotide nucleotidyltransferase activity
FJN15_RS08640	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FJN15_RS08645	COG1196	nuclear chromosome segregation
FJN15_RS08655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJN15_RS08670	COG1132	(ABC) transporter
FJN15_RS08675	COG1663	tetraacyldisaccharide 4'-kinase activity
FJN15_RS08710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FJN15_RS08715	COG0435	Glutathione S-transferase
FJN15_RS08720	COG1741	Belongs to the pirin family
FJN15_RS08725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJN15_RS08735	COG0372	Belongs to the citrate synthase family
FJN15_RS08745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FJN15_RS08750	COG1053	succinate dehydrogenase
FJN15_RS08755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJN15_RS08760	COG0567	Dehydrogenase, E1 component
FJN15_RS08765	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJN15_RS08815	COG4667	esterase of the alpha-beta hydrolase superfamily
FJN15_RS08835	COG0366	Alpha amylase catalytic
FJN15_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS08865	COG2267	carboxylic ester hydrolase activity
FJN15_RS08875	COG0616	signal peptide processing
FJN15_RS08895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJN15_RS08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJN15_RS08905	COG0386	Belongs to the glutathione peroxidase family
FJN15_RS08910	COG2084	Dehydrogenase
FJN15_RS08920	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS08925	COG1024	Enoyl-CoA hydratase
FJN15_RS08930	COG2226	methyltransferase
FJN15_RS08935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FJN15_RS08940	COG3083	sulfuric ester hydrolase activity
FJN15_RS08945	COG3082	Protein of unknown function (DUF1414)
FJN15_RS08950	COG3081	Nucleoid-associated protein
FJN15_RS08980	COG3275	phosphorelay sensor kinase activity
FJN15_RS08985	COG3279	Response regulator of the LytR AlgR family
FJN15_RS08990	COG0205	6-phosphofructokinase activity
FJN15_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJN15_RS09040	COG2205	protein histidine kinase activity
FJN15_RS09050	COG1054	Belongs to the UPF0176 family
FJN15_RS09075	COG0513	Belongs to the DEAD box helicase family
FJN15_RS09085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FJN15_RS09090	COG0583	DNA-binding transcription factor activity
FJN15_RS09110	COG1760	l-serine dehydratase
FJN15_RS09130	COG1322	Protein conserved in bacteria
FJN15_RS09135	COG1404	Belongs to the peptidase S8 family
FJN15_RS09140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FJN15_RS09145	COG0022	dehydrogenase e1 component
FJN15_RS09155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FJN15_RS09160	COG0515	serine threonine protein kinase
FJN15_RS09165	COG1946	Acyl-CoA thioesterase
FJN15_RS09175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJN15_RS09185	COG1956	GAF domain-containing protein
FJN15_RS09200	COG0793	Belongs to the peptidase S41A family
FJN15_RS09205	COG0733	neurotransmitter:sodium symporter activity
FJN15_RS09210	COG1757	Na H antiporter
FJN15_RS09215	COG0308	aminopeptidase N
FJN15_RS09245	COG2902	Dehydrogenase
FJN15_RS09250	COG0167	dihydroorotate dehydrogenase activity
FJN15_RS09265	COG0488	(ABC) transporter
FJN15_RS09275	COG3130	regulation of translation
FJN15_RS09280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJN15_RS09290	COG0415	Belongs to the DNA photolyase family
FJN15_RS09295	COG0415	Belongs to the DNA photolyase family
FJN15_RS09300	COG0415	Belongs to the DNA photolyase family
FJN15_RS09305	COG3046	protein related to deoxyribodipyrimidine photolyase
FJN15_RS09340	COG1082	Xylose isomerase domain protein TIM barrel
FJN15_RS09365	COG4974	Belongs to the 'phage' integrase family
FJN15_RS09375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FJN15_RS09380	COG0589	response to stress
FJN15_RS09390	COG0069	glutamate synthase activity
FJN15_RS09405	COG2193	ferroxidase activity
FJN15_RS09415	COG3278	Belongs to the heme-copper respiratory oxidase family
FJN15_RS09430	COG2010	Cytochrome c
FJN15_RS09455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJN15_RS09460	COG0589	response to stress
FJN15_RS09465	COG0037	tRNA processing
FJN15_RS09470	COG1752	Esterase of the alpha-beta hydrolase superfamily
FJN15_RS09490	COG1280	lysine exporter protein (LysE YggA)
FJN15_RS09500	COG2897	thiosulfate sulfurtransferase activity
FJN15_RS09505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJN15_RS09510	COG3148	PFAM DTW domain containing protein
FJN15_RS09535	COG0322	excinuclease ABC activity
FJN15_RS09540	COG2197	response regulator
FJN15_RS09545	COG0436	Aminotransferase
FJN15_RS09550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FJN15_RS09570	COG2259	Doxx family
FJN15_RS09575	COG0583	DNA-binding transcription factor activity
FJN15_RS09590	COG0670	Belongs to the BI1 family
FJN15_RS09595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FJN15_RS09610	COG2920	part of a sulfur-relay system
FJN15_RS09640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FJN15_RS09650	COG0531	amino acid
FJN15_RS09650	COG1674	ftsk spoiiie
FJN15_RS09660	COG0686	Belongs to the AlaDH PNT family
FJN15_RS09665	COG0284	orotidine-5'-phosphate decarboxylase activity
FJN15_RS09670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FJN15_RS09685	COG0776	regulation of translation
FJN15_RS09690	COG0539	negative regulation of cytoplasmic translation
FJN15_RS09695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FJN15_RS09700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJN15_RS09705	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FJN15_RS09715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJN15_RS09720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJN15_RS09725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJN15_RS09730	COG0633	Ferredoxin
FJN15_RS09760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FJN15_RS09765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJN15_RS09775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FJN15_RS09785	COG4783	chaperone-mediated protein folding
FJN15_RS09795	COG1393	Belongs to the ArsC family
FJN15_RS09810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJN15_RS09825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FJN15_RS09835	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS09860	COG0572	uridine kinase
FJN15_RS09865	COG3769	mannosylglycerate metabolic process
FJN15_RS09870	COG1215	transferase activity, transferring glycosyl groups
FJN15_RS09875	COG0366	Alpha amylase catalytic
FJN15_RS09885	COG0303	'Molybdopterin
FJN15_RS09890	COG0534	Mate efflux family protein
FJN15_RS09905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJN15_RS09910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FJN15_RS10005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJN15_RS10020	COG3547	Transposase (IS116 IS110 IS902 family)
FJN15_RS10075	COG0405	Gamma-glutamyltransferase
FJN15_RS10080	COG1024	Enoyl-CoA hydratase
FJN15_RS10125	COG1448	Aminotransferase
FJN15_RS10140	COG1671	Belongs to the UPF0178 family
FJN15_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS10155	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS10160	COG2207	Transcriptional regulator
FJN15_RS10160	COG0662	Cupin 2, conserved barrel domain protein
FJN15_RS10165	COG4771	TonB-dependent receptor
FJN15_RS10175	COG1505	serine-type exopeptidase activity
FJN15_RS10185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS10215	COG0596	Alpha beta hydrolase
FJN15_RS10225	COG0716	FMN binding
FJN15_RS10235	COG0735	belongs to the Fur family
FJN15_RS10245	COG1984	allophanate hydrolase subunit 2
FJN15_RS10250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FJN15_RS10255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FJN15_RS10260	COG2996	Protein conserved in bacteria
FJN15_RS10265	COG1765	OsmC-like protein
FJN15_RS10270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS10280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJN15_RS10295	COG0436	Aminotransferase
FJN15_RS10300	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FJN15_RS10305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FJN15_RS10330	COG3012	SEC-C Motif Domain Protein
FJN15_RS10335	COG3447	MASE1 domain protein
FJN15_RS10335	COG5001	Diguanylate cyclase
FJN15_RS10335	COG5002	protein histidine kinase activity
FJN15_RS10340	COG0366	Alpha amylase catalytic
FJN15_RS10350	COG0604	alcohol dehydrogenase
FJN15_RS10360	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS10370	COG4771	TonB-dependent receptor
FJN15_RS10395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FJN15_RS10395	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FJN15_RS10410	COG0314	molybdopterin synthase activity
FJN15_RS10415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FJN15_RS10420	COG0315	cyclic pyranopterin monophosphate synthase activity
FJN15_RS10425	COG0521	Mo-molybdopterin cofactor biosynthetic process
FJN15_RS10430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FJN15_RS10470	COG0436	Aminotransferase
FJN15_RS10475	COG3268	Saccharopine dehydrogenase
FJN15_RS10480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJN15_RS10500	COG4206	TonB-dependent receptor
FJN15_RS10510	COG5006	permease, DMT superfamily
FJN15_RS10525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJN15_RS10530	COG1074	ATP-dependent DNA helicase activity
FJN15_RS10535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FJN15_RS10545	COG1022	Amp-dependent synthetase and ligase
FJN15_RS10550	COG4251	negative regulation of phosphorylation
FJN15_RS10550	COG5001	Diguanylate cyclase
FJN15_RS10550	COG3706	GGDEF domain
FJN15_RS10550	COG2203	Gaf domain
FJN15_RS10570	COG0583	DNA-binding transcription factor activity
FJN15_RS10585	COG0640	Transcriptional regulator
FJN15_RS10605	COG2204	response regulator
FJN15_RS10615	COG4251	negative regulation of phosphorylation
FJN15_RS10620	COG0784	Response regulator, receiver
FJN15_RS10625	COG0784	Response regulator, receiver
FJN15_RS10625	COG2205	protein histidine kinase activity
FJN15_RS10650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FJN15_RS10675	COG3139	Protein of unknown function (DUF1315)
FJN15_RS10685	COG1115	amino acid carrier protein
FJN15_RS10690	COG2866	Carboxypeptidase
FJN15_RS10710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FJN15_RS10720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FJN15_RS10725	COG1640	4-alpha-glucanotransferase
FJN15_RS10730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FJN15_RS10735	COG0676	glucose-6-phosphate 1-epimerase activity
FJN15_RS10740	COG0800	Aldolase
FJN15_RS10750	COG0129	dihydroxy-acid dehydratase activity
FJN15_RS10760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FJN15_RS10765	COG1737	Transcriptional regulator
FJN15_RS10770	COG0469	pyruvate kinase activity
FJN15_RS10775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJN15_RS10790	COG2823	Periplasmic or secreted lipoprotein
FJN15_RS10815	COG3665	Urea carboxylase-associated protein
FJN15_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS10840	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FJN15_RS10850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FJN15_RS10865	COG2721	sulfolactate sulfo-lyase activity
FJN15_RS10870	COG1904	glucuronate isomerase
FJN15_RS10875	COG0246	Mannitol dehydrogenase
FJN15_RS10880	COG0800	Aldolase
FJN15_RS10885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJN15_RS10890	COG2755	lipolytic protein G-D-S-L family
FJN15_RS10900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FJN15_RS10925	COG2356	endonuclease I
FJN15_RS10945	COG0583	DNA-binding transcription factor activity
FJN15_RS10950	COG1979	alcohol dehydrogenase
FJN15_RS10955	COG5001	Diguanylate cyclase
FJN15_RS10965	COG3437	response regulator, receiver
FJN15_RS10965	COG0784	Response regulator, receiver
FJN15_RS10970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJN15_RS10970	COG4191	Histidine kinase
FJN15_RS10990	COG0471	metal ion transport
FJN15_RS11000	COG0489	protein tyrosine kinase activity
FJN15_RS11005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJN15_RS11005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJN15_RS11010	COG0668	transmembrane transport
FJN15_RS11015	COG2226	methyltransferase
FJN15_RS11020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FJN15_RS11025	COG0741	lytic transglycosylase activity
FJN15_RS11025	COG1388	LysM domain
FJN15_RS11035	COG0215	cysteine-tRNA ligase activity
FJN15_RS11040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJN15_RS11045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJN15_RS11055	COG2268	Band 7 protein
FJN15_RS11070	COG1733	regulation of RNA biosynthetic process
FJN15_RS11075	COG0604	alcohol dehydrogenase
FJN15_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS11090	COG0753	catalase activity
FJN15_RS11095	COG0604	alcohol dehydrogenase
FJN15_RS11135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FJN15_RS11140	COG1286	toxin biosynthetic process
FJN15_RS11145	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FJN15_RS11150	COG0285	dihydrofolate synthase activity
FJN15_RS11170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FJN15_RS11175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJN15_RS11195	COG3609	addiction module antidote protein, CC2985 family
FJN15_RS11200	COG0583	DNA-binding transcription factor activity
FJN15_RS11205	COG0697	spore germination
FJN15_RS11220	COG2080	2 iron, 2 sulfur cluster binding
FJN15_RS11240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJN15_RS11245	COG0318	PFAM AMP-dependent synthetase and ligase
FJN15_RS11255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJN15_RS11255	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FJN15_RS11290	COG0789	Transcriptional regulator
FJN15_RS11295	COG0604	alcohol dehydrogenase
FJN15_RS11315	COG0583	DNA-binding transcription factor activity
FJN15_RS11320	COG1309	transcriptional regulator
FJN15_RS11330	COG4221	oxidoreductase activity
FJN15_RS11365	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS11370	COG0583	DNA-binding transcription factor activity
FJN15_RS11380	COG2814	Major facilitator Superfamily
FJN15_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS11410	COG1119	ATPase activity
FJN15_RS11415	COG2031	fatty acid transporter
FJN15_RS11420	COG2205	protein histidine kinase activity
FJN15_RS11420	COG5002	protein histidine kinase activity
FJN15_RS11420	COG0784	Response regulator, receiver
FJN15_RS11430	COG0612	Peptidase, M16
FJN15_RS11445	COG3101	peptidyl-lysine hydroxylation
FJN15_RS11475	COG1902	pentaerythritol trinitrate reductase activity
FJN15_RS11475	COG0446	pyridine nucleotide-disulphide oxidoreductase
FJN15_RS11500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FJN15_RS11510	COG4399	Belongs to the UPF0754 family
FJN15_RS11535	COG1770	oligopeptidase
FJN15_RS11540	COG2186	Transcriptional regulator
FJN15_RS11550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FJN15_RS11555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FJN15_RS11565	COG2983	Belongs to the UPF0260 family
FJN15_RS11570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJN15_RS11585	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FJN15_RS11590	COG0318	PFAM AMP-dependent synthetase and ligase
FJN15_RS11595	COG2267	carboxylic ester hydrolase activity
FJN15_RS11610	COG1214	PFAM Peptidase M22, glycoprotease
FJN15_RS11615	COG1199	ATP-dependent helicase activity
FJN15_RS11665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FJN15_RS11670	COG4771	TonB-dependent receptor
FJN15_RS11680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FJN15_RS11685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJN15_RS11690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJN15_RS11695	COG0131	Imidazoleglycerol-phosphate dehydratase
FJN15_RS11695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FJN15_RS11700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FJN15_RS11720	COG2116	formate transmembrane transporter activity
FJN15_RS11755	COG0326	Molecular chaperone. Has ATPase activity
FJN15_RS11760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FJN15_RS11780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FJN15_RS11785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FJN15_RS11795	COG3220	belongs to the UPF0276 family
FJN15_RS11805	COG0577	efflux transmembrane transporter activity
FJN15_RS11805	COG1136	(ABC) transporter
FJN15_RS11815	COG4251	negative regulation of phosphorylation
FJN15_RS11815	COG3706	GGDEF domain
FJN15_RS11815	COG2203	Gaf domain
FJN15_RS11815	COG5001	Diguanylate cyclase
FJN15_RS11830	COG1183	phosphatidylcholine synthase activity
FJN15_RS11850	COG0277	FAD linked oxidase domain protein
FJN15_RS11855	COG0542	response to heat
FJN15_RS11860	COG1496	oxidoreductase activity
FJN15_RS11880	COG1595	DNA-templated transcription, initiation
FJN15_RS11895	COG4221	oxidoreductase activity
FJN15_RS11910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJN15_RS11920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FJN15_RS11930	COG0142	geranyltranstransferase activity
FJN15_RS11940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FJN15_RS11945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FJN15_RS11955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FJN15_RS11970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJN15_RS11970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJN15_RS11985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJN15_RS11990	COG0488	(ABC) transporter
FJN15_RS12000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FJN15_RS12010	COG0560	Phosphoserine phosphatase
FJN15_RS12020	COG0084	hydrolase, TatD family'
FJN15_RS12035	COG0571	ribonuclease III activity
FJN15_RS12065	COG1595	DNA-templated transcription, initiation
FJN15_RS12070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FJN15_RS12085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FJN15_RS12165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FJN15_RS12170	COG1047	Peptidyl-prolyl cis-trans
FJN15_RS12180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FJN15_RS12185	COG0196	riboflavin kinase activity
FJN15_RS12190	COG0728	peptidoglycan biosynthetic process
FJN15_RS12195	COG0268	Binds directly to 16S ribosomal RNA
FJN15_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS12215	COG0385	Bile acid
FJN15_RS12220	COG0583	DNA-binding transcription factor activity
FJN15_RS12245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJN15_RS12250	COG0776	regulation of translation
FJN15_RS12255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJN15_RS12260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJN15_RS12265	COG0740	serine-type endopeptidase activity
FJN15_RS12270	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJN15_RS12325	COG1720	tRNA m6t6A37 methyltransferase activity
FJN15_RS12335	COG1234	tRNA 3'-trailer cleavage
FJN15_RS12345	COG0123	including yeast histone deacetylase and acetoin utilization protein
FJN15_RS12360	COG0517	IMP dehydrogenase activity
FJN15_RS12360	COG0516	GMP reductase activity
FJN15_RS12365	COG1570	exodeoxyribonuclease VII activity
FJN15_RS12380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJN15_RS12385	COG2976	Protein conserved in bacteria
FJN15_RS12410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FJN15_RS12420	COG2166	iron-sulfur cluster assembly
FJN15_RS12435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FJN15_RS12440	COG0719	Fe-S assembly protein
FJN15_RS12445	COG0396	ATPase activity
FJN15_RS12450	COG0719	Fe-S assembly protein
FJN15_RS12455	COG1104	cysteine desulfurase activity
FJN15_RS12460	COG1959	2 iron, 2 sulfur cluster binding
FJN15_RS12465	COG2072	flavoprotein involved in K transport
FJN15_RS12470	COG1045	serine acetyltransferase
FJN15_RS12475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FJN15_RS12480	COG0483	inositol monophosphate 1-phosphatase activity
FJN15_RS12495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJN15_RS12500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJN15_RS12505	COG1862	Preprotein translocase
FJN15_RS12510	COG0343	queuine tRNA-ribosyltransferase activity
FJN15_RS12530	COG1842	Phage shock protein A
FJN15_RS12535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJN15_RS12555	COG0754	glutathionylspermidine amidase activity
FJN15_RS12585	COG2066	Belongs to the glutaminase family
FJN15_RS12590	COG1785	Belongs to the alkaline phosphatase family
FJN15_RS12595	COG0745	RESPONSE REGULATOR receiver
FJN15_RS12695	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS12710	COG0367	asparagine synthase
FJN15_RS12725	COG2327	Polysaccharide pyruvyl transferase
FJN15_RS12775	COG2244	polysaccharide biosynthetic process
FJN15_RS12780	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS12785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FJN15_RS12785	COG2755	lipolytic protein G-D-S-L family
FJN15_RS12815	COG0489	protein tyrosine kinase activity
FJN15_RS12825	COG3267	Type II secretory pathway component ExeA
FJN15_RS12825	COG3409	Peptidoglycan-binding domain 1 protein
FJN15_RS12830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJN15_RS12830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJN15_RS12855	COG1560	Kdo2-lipid A biosynthetic process
FJN15_RS12870	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS12885	COG3300	MHYT domain
FJN15_RS12885	COG5001	Diguanylate cyclase
FJN15_RS12890	COG1435	thymidine kinase activity
FJN15_RS12900	COG1609	Transcriptional regulator
FJN15_RS12905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FJN15_RS12935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FJN15_RS12940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJN15_RS12945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FJN15_RS12945	COG1024	Enoyl-CoA hydratase
FJN15_RS12960	COG1012	belongs to the aldehyde dehydrogenase family
FJN15_RS12980	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FJN15_RS12985	COG0789	Transcriptional regulator
FJN15_RS13015	COG1960	acyl-CoA dehydrogenase activity
FJN15_RS13035	COG0745	RESPONSE REGULATOR receiver
FJN15_RS13040	COG2205	protein histidine kinase activity
FJN15_RS13080	COG2080	2 iron, 2 sulfur cluster binding
FJN15_RS13085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FJN15_RS13090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FJN15_RS13110	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS13115	COG4221	oxidoreductase activity
FJN15_RS13120	COG0693	protein deglycase activity
FJN15_RS13125	COG1295	ribonuclease BN
FJN15_RS13170	COG2814	Major facilitator Superfamily
FJN15_RS13190	COG0514	ATP-dependent DNA helicase (RecQ)
FJN15_RS13225	COG2133	pyrroloquinoline quinone binding
FJN15_RS13275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FJN15_RS13275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FJN15_RS13290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FJN15_RS13295	COG2971	BadF BadG BcrA BcrD
FJN15_RS13300	COG0583	DNA-binding transcription factor activity
FJN15_RS13305	COG1620	l-lactate permease
FJN15_RS13330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJN15_RS13335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FJN15_RS13340	COG0006	proline dipeptidase activity
FJN15_RS13355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJN15_RS13370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FJN15_RS13375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FJN15_RS13380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJN15_RS13400	COG3313	Fe-S protein
FJN15_RS13435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJN15_RS13440	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJN15_RS13445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FJN15_RS13460	COG3023	N-Acetylmuramoyl-L-alanine amidase
FJN15_RS13465	COG3577	Aspartyl protease
FJN15_RS13470	COG0157	Belongs to the NadC ModD family
FJN15_RS13475	COG4969	Belongs to the N-Me-Phe pilin family
FJN15_RS13480	COG1459	type II secretion system
FJN15_RS13485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FJN15_RS13490	COG0237	dephospho-CoA kinase activity
FJN15_RS13490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FJN15_RS13495	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FJN15_RS13500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FJN15_RS13505	COG3608	succinylglutamate desuccinylase aspartoacylase
FJN15_RS13510	COG0494	nUDIX hydrolase
FJN15_RS13520	COG0739	heme binding
FJN15_RS13525	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FJN15_RS13530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FJN15_RS13535	COG0849	cell division
FJN15_RS13540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FJN15_RS13545	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJN15_RS13550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FJN15_RS13560	COG0772	Belongs to the SEDS family
FJN15_RS13565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FJN15_RS13575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FJN15_RS13580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FJN15_RS13585	COG0768	penicillin binding
FJN15_RS13590	COG3116	cell division
FJN15_RS13600	COG2001	Belongs to the MraZ family
FJN15_RS13620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJN15_RS13625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS13645	COG0678	peroxiredoxin activity
FJN15_RS13645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FJN15_RS13670	COG2204	response regulator
FJN15_RS13675	COG2205	protein histidine kinase activity
FJN15_RS13675	COG0784	Response regulator, receiver
FJN15_RS13690	COG2271	Major facilitator Superfamily
FJN15_RS13715	COG0668	transmembrane transport
FJN15_RS13720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FJN15_RS13725	COG0189	ligase activity
FJN15_RS13730	COG1678	Uncharacterized ACR, COG1678
FJN15_RS13735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FJN15_RS13760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FJN15_RS13765	COG0762	integral membrane protein
FJN15_RS13775	COG0446	pyridine nucleotide-disulphide oxidoreductase
FJN15_RS13775	COG1902	pentaerythritol trinitrate reductase activity
FJN15_RS13790	COG0625	glutathione transferase activity
FJN15_RS13800	COG1764	response to oxidative stress
FJN15_RS13820	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FJN15_RS13830	COG2814	Major facilitator Superfamily
FJN15_RS13835	COG0724	RNA recognition motif
FJN15_RS13860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FJN15_RS13865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FJN15_RS13870	COG0083	homoserine kinase activity
FJN15_RS13885	COG0583	DNA-binding transcription factor activity
FJN15_RS13900	COG0640	Transcriptional regulator
FJN15_RS13910	COG0431	NADPH-dependent FMN reductase
FJN15_RS13915	COG0798	PFAM Bile acid sodium symporter
FJN15_RS13920	COG2201	protein-glutamate methylesterase activity
FJN15_RS13925	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FJN15_RS13935	COG5002	protein histidine kinase activity
FJN15_RS13935	COG3850	Histidine kinase
FJN15_RS13950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FJN15_RS13980	COG1748	Saccharopine dehydrogenase
FJN15_RS13995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FJN15_RS14000	COG3107	peptidoglycan biosynthetic process
FJN15_RS14020	COG2823	Periplasmic or secreted lipoprotein
FJN15_RS14040	COG4585	Histidine kinase
FJN15_RS14045	COG2197	response regulator
FJN15_RS14070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FJN15_RS14075	COG0372	Belongs to the citrate synthase family
FJN15_RS14080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FJN15_RS14085	COG2828	Protein conserved in bacteria
FJN15_RS14090	COG2203	Gaf domain
FJN15_RS14090	COG2199	diguanylate cyclase activity
FJN15_RS14095	COG1940	carbohydrate kinase activity
FJN15_RS14115	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FJN15_RS14135	COG2198	Histidine kinase
FJN15_RS14135	COG5002	protein histidine kinase activity
FJN15_RS14135	COG0784	Response regulator, receiver
FJN15_RS14140	COG3023	N-Acetylmuramoyl-L-alanine amidase
FJN15_RS14145	COG0070	glutamate synthase
FJN15_RS14145	COG0067	glutamate synthase
FJN15_RS14145	COG0069	glutamate synthase activity
FJN15_RS14150	COG0493	'glutamate synthase
FJN15_RS14165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJN15_RS14170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FJN15_RS14175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FJN15_RS14180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FJN15_RS14195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJN15_RS14200	COG5507	3-demethylubiquinone-9 3-methyltransferase
FJN15_RS14205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FJN15_RS14210	COG4942	peptidase
FJN15_RS14215	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FJN15_RS14220	COG0738	Major facilitator superfamily
FJN15_RS14230	COG1902	pentaerythritol trinitrate reductase activity
FJN15_RS14250	COG0625	glutathione transferase activity
FJN15_RS14275	COG2894	cell division
FJN15_RS14280	COG0850	regulation of cytokinetic process
FJN15_RS14290	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FJN15_RS14310	COG1981	membrane
FJN15_RS14325	COG1914	H( )-stimulated, divalent metal cation uptake system
FJN15_RS14340	COG1217	gtp-binding protein TYPA
FJN15_RS14345	COG0174	glutamine synthetase
FJN15_RS14355	COG3852	Histidine kinase
FJN15_RS14360	COG2204	response regulator
FJN15_RS14365	COG3655	Transcriptional regulator
FJN15_RS14380	COG3437	response regulator, receiver
FJN15_RS14420	COG2205	protein histidine kinase activity
FJN15_RS14420	COG3437	response regulator, receiver
FJN15_RS14420	COG3850	Histidine kinase
FJN15_RS14420	COG4999	Histidine kinase
FJN15_RS14425	COG0525	valine-tRNA ligase activity
FJN15_RS14430	COG2927	DNA polymerase III (CHI subunit)
FJN15_RS14435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJN15_RS14440	COG0795	lipopolysaccharide-transporting ATPase activity
FJN15_RS14445	COG0795	lipopolysaccharide-transporting ATPase activity
FJN15_RS14515	COG3459	Glycosyltransferase 36 associated
FJN15_RS14525	COG2203	Gaf domain
FJN15_RS14525	COG2199	diguanylate cyclase activity
FJN15_RS14550	COG0673	inositol 2-dehydrogenase activity
FJN15_RS14555	COG0784	Response regulator, receiver
FJN15_RS14555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJN15_RS14555	COG2198	Histidine kinase
FJN15_RS14555	COG2205	protein histidine kinase activity
FJN15_RS14560	COG0628	permease
FJN15_RS14575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FJN15_RS14580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJN15_RS14585	COG4558	Periplasmic binding protein
FJN15_RS14595	COG4206	TonB-dependent receptor
FJN15_RS14605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FJN15_RS14635	COG4771	TonB-dependent receptor
FJN15_RS14645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS14680	COG1609	Transcriptional regulator
FJN15_RS14685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJN15_RS14705	COG4447	cellulose binding
FJN15_RS14715	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FJN15_RS14725	COG0006	proline dipeptidase activity
FJN15_RS14730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FJN15_RS14740	COG0679	Auxin Efflux Carrier
FJN15_RS14750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJN15_RS14760	COG0395	ABC-type sugar transport system, permease component
FJN15_RS14780	COG2267	carboxylic ester hydrolase activity
FJN15_RS14810	COG1131	(ABC) transporter
FJN15_RS14820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJN15_RS14875	COG2205	protein histidine kinase activity
FJN15_RS14885	COG0348	domain, Protein
FJN15_RS14885	COG3901	Regulator of nitric oxide reductase transcription
FJN15_RS14895	COG2197	response regulator
FJN15_RS14930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FJN15_RS14945	COG4771	TonB-dependent receptor
FJN15_RS14955	COG0277	FAD linked oxidase domain protein
FJN15_RS14965	COG1462	curli production assembly transport component CsgG
FJN15_RS14995	COG2197	response regulator
FJN15_RS15020	COG0513	Belongs to the DEAD box helicase family
FJN15_RS15025	COG5001	Diguanylate cyclase
FJN15_RS15040	COG0800	Aldolase
FJN15_RS15045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJN15_RS15060	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FJN15_RS15060	COG3264	Mechanosensitive ion channel
FJN15_RS15100	COG0730	response to heat
FJN15_RS15105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJN15_RS15120	COG4191	Histidine kinase
FJN15_RS15130	COG0417	DNA replication proofreading
FJN15_RS15140	COG0318	PFAM AMP-dependent synthetase and ligase
FJN15_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS15175	COG3119	arylsulfatase activity
FJN15_RS15175	COG3408	Glycogen debranching enzyme
FJN15_RS15190	COG1192	Involved in chromosome partitioning
FJN15_RS15220	COG3119	arylsulfatase activity
FJN15_RS15230	COG3507	Belongs to the glycosyl hydrolase 43 family
FJN15_RS15265	COG0604	alcohol dehydrogenase
FJN15_RS15275	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FJN15_RS15285	COG3119	arylsulfatase activity
FJN15_RS15295	COG3119	arylsulfatase activity
FJN15_RS15295	COG3408	Glycogen debranching enzyme
FJN15_RS15310	COG3119	arylsulfatase activity
FJN15_RS15320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FJN15_RS15335	COG3254	rhamnose metabolic process
FJN15_RS15340	COG4677	pectinesterase activity
FJN15_RS15355	COG3408	Glycogen debranching enzyme
FJN15_RS15360	COG0477	Major facilitator Superfamily
FJN15_RS15365	COG2207	Transcriptional regulator
FJN15_RS15365	COG1609	Transcriptional regulator
FJN15_RS15370	COG1070	Carbohydrate kinase
FJN15_RS15375	COG2115	Belongs to the xylose isomerase family
FJN15_RS15395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FJN15_RS15400	COG0569	domain protein
FJN15_RS15405	COG0745	RESPONSE REGULATOR receiver
FJN15_RS15410	COG2205	protein histidine kinase activity
FJN15_RS15470	COG3940	Belongs to the glycosyl hydrolase 43 family
FJN15_RS15480	COG3250	beta-galactosidase activity
FJN15_RS15540	COG0789	Transcriptional regulator
FJN15_RS15545	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FJN15_RS15550	COG3119	arylsulfatase activity
FJN15_RS15585	COG3940	Belongs to the glycosyl hydrolase 43 family
FJN15_RS15650	COG1304	FMN binding
FJN15_RS15655	COG4952	isomerase
FJN15_RS15660	COG3347	Dehydrogenase
FJN15_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
FJN15_RS15710	COG1309	transcriptional regulator
FJN15_RS15720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJN15_RS15730	COG1573	uracil-dna glycosylase
FJN15_RS15735	COG3300	MHYT domain
FJN15_RS15735	COG5001	Diguanylate cyclase
FJN15_RS15755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FJN15_RS15775	COG1983	PspC domain protein
FJN15_RS15780	COG1842	Phage shock protein A
FJN15_RS15790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJN15_RS15810	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS15840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJN15_RS15850	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FJN15_RS15855	COG0204	Acyl-transferase
FJN15_RS15860	COG0204	Acyl-transferase
FJN15_RS15865	COG0668	transmembrane transport
FJN15_RS15880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJN15_RS15885	COG0733	neurotransmitter:sodium symporter activity
FJN15_RS15900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJN15_RS15925	COG0848	biopolymer transport protein
FJN15_RS15935	COG0457	Tetratricopeptide repeat
FJN15_RS15940	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FJN15_RS15950	COG1215	transferase activity, transferring glycosyl groups
FJN15_RS15965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FJN15_RS15970	COG0702	epimerase
FJN15_RS15985	COG5001	Diguanylate cyclase
FJN15_RS15985	COG5002	protein histidine kinase activity
FJN15_RS15995	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FJN15_RS16005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FJN15_RS16015	COG0583	DNA-binding transcription factor activity
FJN15_RS16020	COG0121	glutamine amidotransferase
FJN15_RS16030	COG4682	membrane
FJN15_RS16050	COG1953	Uracil, thiamine, allantoin
FJN15_RS16055	COG4771	TonB-dependent receptor
FJN15_RS16065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FJN15_RS16075	COG0596	Alpha beta hydrolase
FJN15_RS16080	COG0251	oxidation-reduction process
FJN15_RS16085	COG1335	isochorismatase
FJN15_RS16090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJN15_RS16095	COG1309	transcriptional regulator
FJN15_RS16110	COG4628	conserved protein (DUF2132)
FJN15_RS16115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FJN15_RS16125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FJN15_RS16140	COG1477	protein flavinylation
FJN15_RS16145	COG2871	sodium ion transport
FJN15_RS16150	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FJN15_RS16155	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FJN15_RS16160	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FJN15_RS16165	COG1805	sodium ion transport
FJN15_RS16170	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FJN15_RS16175	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FJN15_RS16180	COG0545	Peptidyl-prolyl cis-trans isomerase
FJN15_RS16185	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FJN15_RS16200	COG0039	L-malate dehydrogenase activity
FJN15_RS16205	COG1438	arginine binding
FJN15_RS16230	COG0572	uridine kinase
FJN15_RS16235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FJN15_RS16260	COG2176	DNA-directed DNA polymerase activity
FJN15_RS16270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS16290	COG0189	ligase activity
FJN15_RS16300	COG0189	ligase activity
FJN15_RS16300	COG4067	protein conserved in archaea
FJN15_RS16315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJN15_RS16325	COG1283	sodium-dependent phosphate transmembrane transporter activity
FJN15_RS16330	COG0667	Aldo Keto reductase
FJN15_RS16355	COG0515	serine threonine protein kinase
FJN15_RS16355	COG2815	serine threonine protein kinase
FJN15_RS16445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FJN15_RS16455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FJN15_RS16480	COG2274	protein secretion by the type I secretion system
FJN15_RS16485	COG0583	DNA-binding transcription factor activity
FJN15_RS16505	COG1091	dTDP-4-dehydrorhamnose reductase activity
FJN15_RS16530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJN15_RS16535	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FJN15_RS16545	COG3119	arylsulfatase activity
FJN15_RS16560	COG0438	transferase activity, transferring glycosyl groups
FJN15_RS16560	COG1216	Glycosyl transferase, family 2
FJN15_RS16575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJN15_RS16585	COG0202	RNA polymerase activity
FJN15_RS16610	COG0201	protein transport
FJN15_RS16630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FJN15_RS16665	COG5002	protein histidine kinase activity
FJN15_RS16665	COG0784	Response regulator, receiver
FJN15_RS16680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJN15_RS16685	COG0557	exoribonuclease II activity
FJN15_RS16730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FJN15_RS16745	COG0543	2 iron, 2 sulfur cluster binding
FJN15_RS16755	COG2234	aminopeptidase activity
FJN15_RS16765	COG4251	negative regulation of phosphorylation
FJN15_RS16785	COG1271	oxidase subunit
FJN15_RS16790	COG1294	oxidase, subunit
FJN15_RS16795	COG1522	sequence-specific DNA binding
FJN15_RS16805	COG1278	Cold shock
FJN15_RS16810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FJN15_RS16830	COG0339	signal peptide processing
FJN15_RS16835	COG2201	protein-glutamate methylesterase activity
FJN15_RS16845	COG3852	Histidine kinase
FJN15_RS16855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJN15_RS16860	COG0243	molybdopterin cofactor binding
FJN15_RS16865	COG1506	peptidase
FJN15_RS16865	COG0823	Involved in the tonB-independent uptake of proteins
FJN15_RS16865	COG4946	Tricorn protease homolog
FJN15_RS16910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJN15_RS16920	COG2197	response regulator
FJN15_RS16930	COG0189	ligase activity
FJN15_RS16950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FJN15_RS16955	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FJN15_RS16960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FJN15_RS16975	COG0281	malic enzyme
FJN15_RS16985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FJN15_RS17015	COG0456	acetyltransferase
FJN15_RS17025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FJN15_RS17030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FJN15_RS17035	COG2177	Part of the ABC transporter FtsEX involved in
FJN15_RS17040	COG2884	Cell division ATP-binding protein ftsE
FJN15_RS17045	COG0552	protein localization to endoplasmic reticulum
FJN15_RS17050	COG0742	ribosomal rna small subunit methyltransferase
FJN15_RS17060	COG2095	MarC family integral membrane protein
FJN15_RS17080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FJN15_RS17085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJN15_RS17090	COG0617	tRNA 3'-terminal CCA addition
FJN15_RS17095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FJN15_RS17110	COG0076	glutamate decarboxylase activity
FJN15_RS17125	COG0842	Transport permease protein
FJN15_RS17130	COG1131	(ABC) transporter
FJN15_RS17135	COG0745	RESPONSE REGULATOR receiver
FJN15_RS17140	COG2205	protein histidine kinase activity
FJN15_RS17145	COG4774	siderophore transport
FJN15_RS17170	COG1253	flavin adenine dinucleotide binding
FJN15_RS17180	COG1966	Carbon starvation protein
FJN15_RS17190	COG0657	acetylesterase activity
FJN15_RS17210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJN15_RS17215	COG0049	tRNA binding
FJN15_RS17220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FJN15_RS17225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FJN15_RS17230	COG0085	RNA polymerase activity
FJN15_RS17235	COG0222	ribosome binding
FJN15_RS17240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FJN15_RS17245	COG0081	regulation of translation
FJN15_RS17250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FJN15_RS17265	COG0250	Participates in transcription elongation, termination and antitermination
FJN15_RS17270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJN15_RS17280	COG1132	(ABC) transporter
FJN15_RS17285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FJN15_RS17290	COG3590	peptidase
FJN15_RS17300	COG0513	Belongs to the DEAD box helicase family
FJN15_RS17305	COG0418	dihydroorotase activity
FJN15_RS17310	COG3040	lipid binding
FJN15_RS17315	COG4989	oxidoreductase activity
FJN15_RS17320	COG0346	lactoylglutathione lyase activity
FJN15_RS17325	COG0668	transmembrane transport
FJN15_RS17340	COG0302	gtp cyclohydrolase
FJN15_RS17350	COG2957	Belongs to the agmatine deiminase family
FJN15_RS17355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJN15_RS17365	COG1201	RNA secondary structure unwinding
FJN15_RS17370	COG2311	Membrane
FJN15_RS17385	COG1793	dna ligase
FJN15_RS17390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJN15_RS17395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FJN15_RS17410	COG0625	glutathione transferase activity
FJN15_RS17415	COG0625	glutathione transferase activity
FJN15_RS17425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FJN15_RS17440	COG1012	belongs to the aldehyde dehydrogenase family
FJN15_RS17445	COG0028	Belongs to the TPP enzyme family
FJN15_RS17455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJN15_RS17460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FJN15_RS17465	COG0330	HflC and HflK could
FJN15_RS17470	COG0330	HflC and HflK could
FJN15_RS17475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FJN15_RS17480	COG1923	regulation of RNA biosynthetic process
FJN15_RS17485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FJN15_RS17500	COG0802	atpase or kinase
FJN15_RS17505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FJN15_RS17505	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FJN15_RS17510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FJN15_RS17530	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FJN15_RS17535	COG0735	belongs to the Fur family
FJN15_RS17555	COG0305	Participates in initiation and elongation during chromosome replication
FJN15_RS17580	COG2258	MOSC domain
FJN15_RS17640	COG2205	protein histidine kinase activity
FJN15_RS17640	COG2198	Histidine kinase
FJN15_RS17640	COG0784	Response regulator, receiver
FJN15_RS17650	COG1136	(ABC) transporter
FJN15_RS17650	COG0577	efflux transmembrane transporter activity
FJN15_RS17660	COG0840	transmembrane signaling receptor activity
FJN15_RS17665	COG5002	protein histidine kinase activity
FJN15_RS17670	COG0840	transmembrane signaling receptor activity
FJN15_RS17685	COG2855	membrane
FJN15_RS17690	COG2175	clavaminate synthase activity
FJN15_RS17695	COG0656	L-ascorbic acid biosynthetic process
FJN15_RS17715	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJN15_RS17720	COG4771	TonB-dependent receptor
FJN15_RS17745	COG1472	Belongs to the glycosyl hydrolase 3 family
FJN15_RS17755	COG2723	6-phospho-beta-galactosidase activity
FJN15_RS17760	COG1609	Transcriptional regulator
FJN15_RS17765	COG0477	Major facilitator Superfamily
FJN15_RS17765	COG2814	Major facilitator Superfamily
FJN15_RS17770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FJN15_RS17775	COG4988	ABC transporter
FJN15_RS17780	COG4890	Cyd operon protein YbgT
FJN15_RS17785	COG1294	oxidase, subunit
FJN15_RS17820	COG4319	ketosteroid isomerase
FJN15_RS17830	COG4771	TonB-dependent receptor
FJN15_RS17845	COG1469	GTP cyclohydrolase I activity
FJN15_RS17860	COG2375	cellular response to nickel ion
FJN15_RS17865	COG3237	CsbD-like
FJN15_RS17880	COG1595	DNA-templated transcription, initiation
FJN15_RS17885	COG1404	Belongs to the peptidase S8 family
FJN15_RS17910	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJN15_RS17910	COG0596	Alpha beta hydrolase
FJN15_RS17940	COG1252	NADH dehydrogenase
FJN15_RS17955	COG0583	DNA-binding transcription factor activity
FJN15_RS17960	COG2067	long-chain fatty acid transport protein
FJN15_RS17965	COG2130	NADP-dependent
FJN15_RS17970	COG3706	GGDEF domain
FJN15_RS17970	COG2203	Gaf domain
FJN15_RS17970	COG4251	negative regulation of phosphorylation
FJN15_RS17970	COG5001	Diguanylate cyclase
FJN15_RS17975	COG2205	protein histidine kinase activity
FJN15_RS17975	COG0784	Response regulator, receiver
FJN15_RS17985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJN15_RS17990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJN15_RS17995	COG1349	DNA-binding transcription factor activity
FJN15_RS18000	COG0673	inositol 2-dehydrogenase activity
FJN15_RS18015	COG0697	spore germination
FJN15_RS18020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FJN15_RS18025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FJN15_RS18030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FJN15_RS18035	COG1166	arginine decarboxylase activity
FJN15_RS18045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FJN15_RS18105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJN15_RS18125	COG3030	protein affecting phage T7 exclusion by the F plasmid
FJN15_RS18130	COG1324	tolerance protein
FJN15_RS18135	COG4232	protein-disulfide reductase activity
FJN15_RS18140	COG0739	heme binding
FJN15_RS18145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJN15_RS18150	COG0511	ligase activity, forming carbon-carbon bonds
FJN15_RS18155	COG0439	Biotin carboxylase
FJN15_RS18195	COG0154	amidase activity
FJN15_RS18210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJN15_RS18215	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FJN15_RS18230	COG0151	Belongs to the GarS family
FJN15_RS18250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJN15_RS18255	COG3954	Phosphoribulokinase
FJN15_RS18280	COG1501	Belongs to the glycosyl hydrolase 31 family
FJN15_RS18285	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FJN15_RS18295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FJN15_RS18305	COG3031	protein transport across the cell outer membrane
FJN15_RS18315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJN15_RS18320	COG1459	type II secretion system
FJN15_RS18325	COG2165	general secretion pathway protein
FJN15_RS18330	COG2165	general secretion pathway protein
FJN15_RS18335	COG2165	general secretion pathway protein
FJN15_RS18340	COG4795	General secretion pathway protein
FJN15_RS18355	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FJN15_RS18370	COG1012	belongs to the aldehyde dehydrogenase family
FJN15_RS18380	COG1011	Hydrolase
FJN15_RS18385	COG0494	nUDIX hydrolase
FJN15_RS18390	COG1218	3'(2'),5'-bisphosphate nucleotidase
FJN15_RS18400	COG2943	transferase activity, transferring hexosyl groups
FJN15_RS18405	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FJN15_RS18415	COG3089	Belongs to the UPF0270 family
FJN15_RS18420	COG0429	hydrolase of the alpha beta-hydrolase fold
FJN15_RS18430	COG0488	(ABC) transporter
FJN15_RS18445	COG2900	Belongs to the SlyX family
FJN15_RS18455	COG0545	Peptidyl-prolyl cis-trans isomerase
FJN15_RS18465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJN15_RS18470	COG2183	response to ionizing radiation
FJN15_RS18490	COG0596	Alpha beta hydrolase
FJN15_RS18495	COG1040	competence protein
FJN15_RS18510	COG1794	racemase activity, acting on amino acids and derivatives
FJN15_RS18525	COG0534	Mate efflux family protein
FJN15_RS18530	COG0726	polysaccharide deacetylase
FJN15_RS18530	COG1649	PFAM Uncharacterised BCR, COG1649
FJN15_RS18540	COG1999	signal sequence binding
FJN15_RS18545	COG0109	protoheme IX farnesyltransferase activity
FJN15_RS18550	COG1612	heme a metabolic process
FJN15_RS18570	COG1845	cytochrome c oxidase, subunit III
FJN15_RS18575	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FJN15_RS18580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FJN15_RS18585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FJN15_RS18605	COG0129	dihydroxy-acid dehydratase activity
FJN15_RS18615	COG0606	chelatase, subunit chli
FJN15_RS18620	COG0583	DNA-binding transcription factor activity
FJN15_RS18630	COG2814	Major facilitator Superfamily
FJN15_RS18635	COG1073	alpha beta
FJN15_RS18640	COG0729	surface antigen
FJN15_RS18645	COG2911	Protein conserved in bacteria
FJN15_RS18670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJN15_RS18680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJN15_RS18700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FJN15_RS18725	COG1228	amidohydrolase
FJN15_RS18750	COG0425	Belongs to the sulfur carrier protein TusA family
FJN15_RS18765	COG1561	YicC-like family, N-terminal region
FJN15_RS18795	COG1403	HNH endonuclease
FJN15_RS18825	COG3177	Filamentation induced by cAMP protein fic
FJN15_RS18845	COG2723	6-phospho-beta-galactosidase activity
FJN15_RS18850	COG2211	Major facilitator Superfamily
FJN15_RS18855	COG1609	Transcriptional regulator
FJN15_RS18870	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJN15_RS18870	COG2199	diguanylate cyclase activity
FJN15_RS18895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FJN15_RS18915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJN15_RS18920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FJN15_RS18940	COG1475	DNA binding
FJN15_RS18945	COG1192	Involved in chromosome partitioning
FJN15_RS18970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FJN15_RS18975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FJN15_RS18985	COG0706	membrane insertase activity
FJN15_RS18990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FJN15_RS18995	COG0594	ribonuclease P activity
FJN15_RS19000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FJN15_RS19005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJN15_RS19015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FJN15_RS19020	COG0187	DNA topoisomerase II activity
FJN15_RS19040	COG2818	Glycosylase
FJN15_RS19050	COG3078	GTPase activator activity
FJN15_RS19070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJN15_RS19070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJN15_RS19075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FJN15_RS19080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FJN15_RS19085	COG0569	domain protein
FJN15_RS19090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FJN15_RS19090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FJN15_RS19095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJN15_RS19110	COG0758	DNA mediated transformation
FJN15_RS19125	COG0009	L-threonylcarbamoyladenylate synthase
FJN15_RS19130	COG0408	coproporphyrinogen oxidase activity
FJN15_RS19135	COG3047	cAMP biosynthetic process
FJN15_RS19150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily