locus-tag	class	description
BM525_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM525_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BM525_RS00025	COG0187	DNA topoisomerase II activity
BM525_RS00055	COG2818	Glycosylase
BM525_RS00065	COG3078	GTPase activator activity
BM525_RS00085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM525_RS00085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM525_RS00090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BM525_RS00095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BM525_RS00100	COG0569	domain protein
BM525_RS00105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM525_RS00105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM525_RS00110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM525_RS00125	COG0758	DNA mediated transformation
BM525_RS00140	COG0009	L-threonylcarbamoyladenylate synthase
BM525_RS00145	COG0408	coproporphyrinogen oxidase activity
BM525_RS00150	COG3047	cAMP biosynthetic process
BM525_RS00165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BM525_RS00240	COG2234	aminopeptidase activity
BM525_RS00245	COG3562	capsule polysaccharide
BM525_RS00255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BM525_RS00280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM525_RS00310	COG3642	lipopolysaccharide core region biosynthetic process
BM525_RS00315	COG0859	PFAM glycosyl transferase family 9
BM525_RS00345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM525_RS00360	COG3161	chorismate lyase activity
BM525_RS00365	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BM525_RS00385	COG0210	DNA helicase
BM525_RS00415	COG1757	Na H antiporter
BM525_RS00430	COG1959	2 iron, 2 sulfur cluster binding
BM525_RS00435	COG0730	response to heat
BM525_RS00465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM525_RS00470	COG4988	ABC transporter
BM525_RS00480	COG1271	oxidase subunit
BM525_RS00485	COG0425	Belongs to the sulfur carrier protein TusA family
BM525_RS00485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM525_RS00495	COG0450	alkyl hydroperoxide reductase
BM525_RS00500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM525_RS00530	COG3727	T/G mismatch-specific endonuclease activity
BM525_RS00555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM525_RS00560	COG0556	nucleotide-excision repair
BM525_RS00570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS00575	COG1129	ABC transporter
BM525_RS00575	COG0842	Transport permease protein
BM525_RS00580	COG0842	Transport permease protein
BM525_RS00590	COG4771	TonB-dependent receptor
BM525_RS00605	COG0583	DNA-binding transcription factor activity
BM525_RS00615	COG3106	COG3106 Predicted ATPase
BM525_RS00630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BM525_RS00650	COG0352	thiamine-phosphate diphosphorylase activity
BM525_RS00660	COG3071	HemY protein
BM525_RS00665	COG2959	enzyme of heme biosynthesis
BM525_RS00675	COG0181	hydroxymethylbilane synthase activity
BM525_RS00690	COG0194	GDP metabolic process
BM525_RS00700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM525_RS00710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM525_RS00715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BM525_RS00725	COG0678	peroxiredoxin activity
BM525_RS00740	COG1178	ABC-type Fe3 transport system permease component
BM525_RS00745	COG3842	ATPase activity
BM525_RS00750	COG0668	transmembrane transport
BM525_RS00755	COG2081	HI0933 family
BM525_RS00765	COG2200	EAL domain
BM525_RS00770	COG0583	DNA-binding transcription factor activity
BM525_RS00795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS00810	COG0427	acetyl-CoA hydrolase
BM525_RS00815	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM525_RS00830	COG0840	transmembrane signaling receptor activity
BM525_RS00840	COG3064	Membrane
BM525_RS00850	COG5002	protein histidine kinase activity
BM525_RS00850	COG5001	Diguanylate cyclase
BM525_RS00865	COG0514	ATP-dependent DNA helicase (RecQ)
BM525_RS00870	COG2239	Acts as a magnesium transporter
BM525_RS00875	COG2962	Rard protein
BM525_RS00885	COG0210	DNA helicase
BM525_RS00895	COG1011	Hydrolase
BM525_RS00900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BM525_RS00910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BM525_RS00915	COG0019	diaminopimelate decarboxylase activity
BM525_RS00945	COG0163	prenyltransferase activity
BM525_RS00950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM525_RS00960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BM525_RS00980	COG1077	Cell shape determining protein MreB Mrl
BM525_RS00995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BM525_RS01000	COG2814	Major facilitator Superfamily
BM525_RS01005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM525_RS01030	COG1085	galactose-1-phosphate uridylyltransferase
BM525_RS01035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BM525_RS01045	COG0629	single-stranded DNA binding
BM525_RS01070	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM525_RS01095	COG1349	DNA-binding transcription factor activity
BM525_RS01140	COG3267	Type II secretory pathway component ExeA
BM525_RS01140	COG3409	Peptidoglycan-binding domain 1 protein
BM525_RS01150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM525_RS01155	COG1459	type II secretion system
BM525_RS01165	COG2165	general secretion pathway protein
BM525_RS01170	COG2165	general secretion pathway protein
BM525_RS01200	COG1077	Cell shape determining protein MreB Mrl
BM525_RS01205	COG1792	Involved in formation and maintenance of cell shape
BM525_RS01210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BM525_RS01220	COG1530	ribonuclease E activity
BM525_RS01230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM525_RS01235	COG0312	modulator of DNA gyrase
BM525_RS01240	COG3028	Belongs to the UPF0307 family
BM525_RS01245	COG0312	modulator of DNA gyrase
BM525_RS01260	COG0745	RESPONSE REGULATOR receiver
BM525_RS01265	COG4191	Histidine kinase
BM525_RS01265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS01270	COG0297	glycogen (starch) synthase activity
BM525_RS01280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BM525_RS01285	COG0596	Alpha beta hydrolase
BM525_RS01325	COG2814	Major facilitator Superfamily
BM525_RS01335	COG0745	RESPONSE REGULATOR receiver
BM525_RS01345	COG0835	chemotaxis
BM525_RS01360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM525_RS01375	COG0745	RESPONSE REGULATOR receiver
BM525_RS01380	COG2198	Histidine kinase
BM525_RS01380	COG0643	Histidine kinase
BM525_RS01385	COG0835	chemotaxis
BM525_RS01405	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM525_RS01480	COG0673	inositol 2-dehydrogenase activity
BM525_RS01490	COG2211	Major facilitator Superfamily
BM525_RS01495	COG1082	Xylose isomerase domain protein TIM barrel
BM525_RS01515	COG1454	alcohol dehydrogenase
BM525_RS01565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM525_RS01585	COG0089	rRNA binding
BM525_RS01595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BM525_RS01605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BM525_RS01620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BM525_RS01625	COG0438	transferase activity, transferring glycosyl groups
BM525_RS01635	COG1519	Transferase
BM525_RS01655	COG0840	transmembrane signaling receptor activity
BM525_RS01670	COG0788	formyltetrahydrofolate deformylase activity
BM525_RS01680	COG1643	Atp-dependent helicase
BM525_RS01685	COG2951	lytic endotransglycosylase activity
BM525_RS01690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM525_RS01700	COG2354	Protein conserved in bacteria
BM525_RS01725	COG0004	ammonium transporteR
BM525_RS01730	COG0405	Gamma-glutamyltransferase
BM525_RS01735	COG2837	iron assimilation
BM525_RS01750	COG0540	Belongs to the ATCase OTCase family
BM525_RS01775	COG3437	response regulator, receiver
BM525_RS01775	COG3850	Histidine kinase
BM525_RS01775	COG4999	Histidine kinase
BM525_RS01775	COG2205	protein histidine kinase activity
BM525_RS01790	COG5001	Diguanylate cyclase
BM525_RS01790	COG3300	MHYT domain
BM525_RS01800	COG1012	belongs to the aldehyde dehydrogenase family
BM525_RS01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM525_RS01825	COG0180	Tryptophanyl-tRNA synthetase
BM525_RS01830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BM525_RS01850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BM525_RS01860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BM525_RS01895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BM525_RS01900	COG0281	malic enzyme
BM525_RS01910	COG0625	glutathione transferase activity
BM525_RS01920	COG0753	catalase activity
BM525_RS01945	COG3300	MHYT domain
BM525_RS01945	COG5001	Diguanylate cyclase
BM525_RS01950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BM525_RS01950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BM525_RS01960	COG0137	argininosuccinate synthase activity
BM525_RS01980	COG1803	Methylglyoxal synthase
BM525_RS01990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BM525_RS02005	COG0745	RESPONSE REGULATOR receiver
BM525_RS02010	COG2205	protein histidine kinase activity
BM525_RS02015	COG2267	carboxylic ester hydrolase activity
BM525_RS02020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BM525_RS02030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BM525_RS02040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM525_RS02045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM525_RS02050	COG4942	peptidase
BM525_RS02055	COG2861	carbohydrate metabolic process
BM525_RS02080	COG1162	GTPase activity
BM525_RS02085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BM525_RS02115	COG0028	Belongs to the TPP enzyme family
BM525_RS02135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BM525_RS02140	COG0805	protein transport
BM525_RS02150	COG0084	hydrolase, TatD family'
BM525_RS02155	COG5001	Diguanylate cyclase
BM525_RS02155	COG4251	negative regulation of phosphorylation
BM525_RS02155	COG3706	GGDEF domain
BM525_RS02155	COG2203	Gaf domain
BM525_RS02165	COG0248	Ppx GppA phosphatase
BM525_RS02170	COG0513	Belongs to the DEAD box helicase family
BM525_RS02175	COG3118	belongs to the thioredoxin family
BM525_RS02180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BM525_RS02185	COG1473	amidohydrolase
BM525_RS02190	COG0784	Response regulator, receiver
BM525_RS02190	COG5002	protein histidine kinase activity
BM525_RS02195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BM525_RS02200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BM525_RS02205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BM525_RS02220	COG0783	Belongs to the Dps family
BM525_RS02225	COG2133	pyrroloquinoline quinone binding
BM525_RS02230	COG4946	Tricorn protease homolog
BM525_RS02230	COG1506	peptidase
BM525_RS02230	COG0823	Involved in the tonB-independent uptake of proteins
BM525_RS02240	COG3118	belongs to the thioredoxin family
BM525_RS02255	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BM525_RS02265	COG1012	belongs to the aldehyde dehydrogenase family
BM525_RS02285	COG1757	Na H antiporter
BM525_RS02300	COG3876	Protein conserved in bacteria
BM525_RS02305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM525_RS02315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BM525_RS02325	COG0346	lactoylglutathione lyase activity
BM525_RS02350	COG2824	Alkylphosphonate utilization operon protein PhnA
BM525_RS02355	COG0454	-acetyltransferase
BM525_RS02375	COG3093	addiction module antidote protein HigA
BM525_RS02445	COG0183	Belongs to the thiolase family
BM525_RS02450	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM525_RS02450	COG1024	Enoyl-CoA hydratase
BM525_RS02460	COG0006	proline dipeptidase activity
BM525_RS02470	COG0142	geranyltranstransferase activity
BM525_RS02500	COG1388	LysM domain
BM525_RS02500	COG4942	peptidase
BM525_RS02505	COG1238	metal cluster binding
BM525_RS02515	COG0585	pseudouridine synthase activity
BM525_RS02520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BM525_RS02530	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BM525_RS02540	COG0840	transmembrane signaling receptor activity
BM525_RS02555	COG5002	protein histidine kinase activity
BM525_RS02580	COG0494	nUDIX hydrolase
BM525_RS02585	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BM525_RS02590	COG0730	response to heat
BM525_RS02595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BM525_RS02600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BM525_RS02605	COG2201	protein-glutamate methylesterase activity
BM525_RS02635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BM525_RS02650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BM525_RS02660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM525_RS02660	COG1648	precorrin-2 dehydrogenase activity
BM525_RS02665	COG0513	Belongs to the DEAD box helicase family
BM525_RS02680	COG1538	Outer membrane efflux protein
BM525_RS02685	COG0494	nUDIX hydrolase
BM525_RS02695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BM525_RS02700	COG3150	esterase
BM525_RS02705	COG0187	DNA topoisomerase II activity
BM525_RS02715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM525_RS02740	COG1509	lysine 2,3-aminomutase activity
BM525_RS02745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM525_RS02750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BM525_RS02765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM525_RS02770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM525_RS02785	COG0271	Belongs to the BolA IbaG family
BM525_RS02790	COG0671	phosphoesterase, PA-phosphatase related
BM525_RS02800	COG3707	response regulator
BM525_RS02815	COG0659	secondary active sulfate transmembrane transporter activity
BM525_RS02825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM525_RS02835	COG0243	molybdopterin cofactor binding
BM525_RS02840	COG1648	precorrin-2 dehydrogenase activity
BM525_RS02840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM525_RS02845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM525_RS02855	COG1116	anion transmembrane transporter activity
BM525_RS02855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM525_RS02865	COG1116	anion transmembrane transporter activity
BM525_RS02880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM525_RS02885	COG4206	TonB-dependent receptor
BM525_RS02890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BM525_RS02895	COG0348	domain, Protein
BM525_RS02910	COG1960	acyl-CoA dehydrogenase activity
BM525_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS02925	COG4948	Mandelate Racemase Muconate Lactonizing
BM525_RS02940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS02945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM525_RS02970	COG0358	DNA primase activity
BM525_RS02975	COG1610	YqeY-like protein
BM525_RS02995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BM525_RS03000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM525_RS03015	COG0537	adenosine 5'-monophosphoramidase activity
BM525_RS03030	COG3135	benzoate transporter
BM525_RS03035	COG1396	sequence-specific DNA binding
BM525_RS03040	COG2974	May be involved in recombination
BM525_RS03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS03045	COG4191	Histidine kinase
BM525_RS03050	COG0745	RESPONSE REGULATOR receiver
BM525_RS03055	COG5002	protein histidine kinase activity
BM525_RS03080	COG0811	peptide transport
BM525_RS03085	COG0811	peptide transport
BM525_RS03090	COG0848	biopolymer transport protein
BM525_RS03095	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BM525_RS03105	COG3437	response regulator, receiver
BM525_RS03125	COG2133	pyrroloquinoline quinone binding
BM525_RS03135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM525_RS03165	COG0527	aspartate kinase activity
BM525_RS03175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BM525_RS03180	COG2967	ApaG domain
BM525_RS03190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BM525_RS03195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM525_RS03200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BM525_RS03205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BM525_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM525_RS03235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BM525_RS03250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM525_RS03255	COG3956	TIGRFAM MazG family protein
BM525_RS03280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BM525_RS03285	COG0723	plastoquinol--plastocyanin reductase activity
BM525_RS03290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BM525_RS03295	COG2857	Cytochrome c1
BM525_RS03300	COG0625	glutathione transferase activity
BM525_RS03305	COG2969	positive regulation of protein catabolic process
BM525_RS03320	COG0745	RESPONSE REGULATOR receiver
BM525_RS03325	COG2239	Acts as a magnesium transporter
BM525_RS03330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM525_RS03350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BM525_RS03355	COG1137	ATPase activity
BM525_RS03360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BM525_RS03370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BM525_RS03385	COG1127	ABC transporter
BM525_RS03390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM525_RS03395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM525_RS03400	COG2854	intermembrane phospholipid transfer
BM525_RS03410	COG5007	Belongs to the BolA IbaG family
BM525_RS03420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM525_RS03425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM525_RS03435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM525_RS03470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM525_RS03485	COG4771	TonB-dependent receptor
BM525_RS03490	COG0697	spore germination
BM525_RS03495	COG2205	protein histidine kinase activity
BM525_RS03495	COG0784	Response regulator, receiver
BM525_RS03520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM525_RS03530	COG0126	phosphoglycerate kinase activity
BM525_RS03535	COG3588	fructose-bisphosphate aldolase
BM525_RS03545	COG0823	Involved in the tonB-independent uptake of proteins
BM525_RS03545	COG1506	peptidase
BM525_RS03545	COG4946	Tricorn protease homolog
BM525_RS03550	COG0248	Ppx GppA phosphatase
BM525_RS03555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BM525_RS03565	COG0573	inorganic phosphate transmembrane transporter activity
BM525_RS03575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BM525_RS03585	COG0306	phosphate transporter
BM525_RS03595	COG0583	DNA-binding transcription factor activity
BM525_RS03605	COG1272	protein, Hemolysin III
BM525_RS03610	COG1846	Transcriptional regulator
BM525_RS03615	COG1764	response to oxidative stress
BM525_RS03630	COG1739	Uncharacterized protein family UPF0029
BM525_RS03650	COG0583	DNA-binding transcription factor activity
BM525_RS03655	COG4989	oxidoreductase activity
BM525_RS03670	COG0420	3'-5' exonuclease activity
BM525_RS03675	COG0419	ATPase involved in DNA repair
BM525_RS03685	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BM525_RS03710	COG2188	Transcriptional regulator
BM525_RS03715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BM525_RS03720	COG2986	histidine ammonia-lyase
BM525_RS03745	COG0488	(ABC) transporter
BM525_RS03770	COG0668	transmembrane transport
BM525_RS03795	COG0582	viral genome integration into host DNA
BM525_RS03800	COG2319	Wd-40 repeat
BM525_RS03800	COG4249	Peptidase C14 caspase catalytic subunit p20
BM525_RS03840	COG1518	maintenance of DNA repeat elements
BM525_RS03845	COG1203	CRISPR-associated helicase, Cas3
BM525_RS03905	COG1346	cytolysis
BM525_RS03935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM525_RS03945	COG0513	Belongs to the DEAD box helicase family
BM525_RS03955	COG3409	Peptidoglycan-binding domain 1 protein
BM525_RS03955	COG3267	Type II secretory pathway component ExeA
BM525_RS03970	COG0066	3-isopropylmalate dehydratase activity
BM525_RS03980	COG0473	3-isopropylmalate dehydrogenase activity
BM525_RS03985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BM525_RS04010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BM525_RS04025	COG4555	ABC transporter
BM525_RS04030	COG1668	transmembrane transport
BM525_RS04040	COG0745	RESPONSE REGULATOR receiver
BM525_RS04070	COG4133	protoheme IX ABC transporter activity
BM525_RS04075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM525_RS04080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM525_RS04085	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM525_RS04095	COG1138	Cytochrome C-type biogenesis protein
BM525_RS04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM525_RS04115	COG2853	Lipoprotein
BM525_RS04120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM525_RS04160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BM525_RS04175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM525_RS04180	COG1596	polysaccharide export
BM525_RS04180	COG1555	photosystem II stabilization
BM525_RS04185	COG0473	3-isopropylmalate dehydrogenase activity
BM525_RS04200	COG1611	Belongs to the LOG family
BM525_RS04210	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM525_RS04210	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM525_RS04265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BM525_RS04270	COG0024	Methionine aminopeptidase
BM525_RS04275	COG0052	Belongs to the universal ribosomal protein uS2 family
BM525_RS04285	COG0528	UMP kinase activity
BM525_RS04300	COG0575	Belongs to the CDS family
BM525_RS04325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM525_RS04345	COG0587	DNA-directed DNA polymerase activity
BM525_RS04350	COG0825	malonyl-CoA metabolic process
BM525_RS04355	COG0037	tRNA processing
BM525_RS04385	COG0047	phosphoribosylformylglycinamidine synthase activity
BM525_RS04385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BM525_RS04390	COG2840	Smr protein MutS2
BM525_RS04420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS04425	COG2197	response regulator
BM525_RS04465	COG0784	Response regulator, receiver
BM525_RS04465	COG0835	chemotaxis
BM525_RS04470	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM525_RS04475	COG1815	bacterial-type flagellum-dependent cell motility
BM525_RS04490	COG1749	Flagellar hook protein flgE
BM525_RS04495	COG4787	bacterial-type flagellum-dependent cell motility
BM525_RS04515	COG3951	Flagellar rod assembly protein muramidase FlgJ
BM525_RS04515	COG1705	Flagellar rod assembly protein muramidase FlgJ
BM525_RS04520	COG1256	bacterial-type flagellum assembly
BM525_RS04545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM525_RS04550	COG1334	flagellar protein FlaG
BM525_RS04555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BM525_RS04575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM525_RS04580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM525_RS04595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BM525_RS04620	COG2089	acid synthase
BM525_RS04635	COG1083	cytidylyl-transferase
BM525_RS04655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BM525_RS04670	COG2089	acid synthase
BM525_RS04680	COG1083	cytidylyl-transferase
BM525_RS04685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM525_RS04690	COG1086	Polysaccharide biosynthesis protein
BM525_RS04695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM525_RS04720	COG1677	Flagellar hook-basal body complex protein FliE
BM525_RS04725	COG1766	The M ring may be actively involved in energy transduction
BM525_RS04730	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BM525_RS04780	COG1987	bacterial-type flagellum assembly
BM525_RS04795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM525_RS04820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BM525_RS04825	COG2198	Histidine kinase
BM525_RS04825	COG0784	Response regulator, receiver
BM525_RS04825	COG0643	Histidine kinase
BM525_RS04835	COG1192	Involved in chromosome partitioning
BM525_RS04845	COG0835	chemotaxis
BM525_RS04860	COG1410	methionine synthase
BM525_RS04860	COG0646	methionine synthase
BM525_RS04865	COG1410	methionine synthase
BM525_RS04865	COG0646	methionine synthase
BM525_RS04875	COG3123	guanosine phosphorylase activity
BM525_RS04885	COG0583	DNA-binding transcription factor activity
BM525_RS04890	COG0583	DNA-binding transcription factor activity
BM525_RS04900	COG0659	secondary active sulfate transmembrane transporter activity
BM525_RS04915	COG3590	peptidase
BM525_RS04925	COG2137	regulation of response to DNA damage stimulus
BM525_RS04930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM525_RS04960	COG0511	ligase activity, forming carbon-carbon bonds
BM525_RS04960	COG5016	pyruvate
BM525_RS04965	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BM525_RS04970	COG4172	Belongs to the ABC transporter superfamily
BM525_RS04980	COG4171	peptide transport system, permease
BM525_RS04985	COG4168	peptide transport system, permease
BM525_RS04990	COG0747	negative chemotaxis
BM525_RS04995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BM525_RS05000	COG1842	Phage shock protein A
BM525_RS05030	COG0625	glutathione transferase activity
BM525_RS05035	COG1522	sequence-specific DNA binding
BM525_RS05100	COG0811	peptide transport
BM525_RS05105	COG0811	peptide transport
BM525_RS05110	COG0848	biopolymer transport protein
BM525_RS05125	COG1444	tRNA N-acetyltransferase activity
BM525_RS05165	COG0456	acetyltransferase
BM525_RS05180	COG0583	DNA-binding transcription factor activity
BM525_RS05185	COG2814	Major facilitator Superfamily
BM525_RS05190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM525_RS05195	COG0656	L-ascorbic acid biosynthetic process
BM525_RS05235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM525_RS05280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BM525_RS05285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM525_RS05290	COG0564	pseudouridine synthase activity
BM525_RS05300	COG0612	Peptidase, M16
BM525_RS05305	COG2918	glutathione biosynthetic process
BM525_RS05320	COG2840	Smr protein MutS2
BM525_RS05325	COG2890	protein-(glutamine-N5) methyltransferase activity
BM525_RS05340	COG2719	SpoVR family
BM525_RS05345	COG2718	Belongs to the UPF0229 family
BM525_RS05350	COG2766	serine protein kinase
BM525_RS05355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BM525_RS05360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BM525_RS05365	COG4771	TonB-dependent receptor
BM525_RS05390	COG0450	alkyl hydroperoxide reductase
BM525_RS05400	COG2885	chlorophyll binding
BM525_RS05405	COG0584	glycerophosphoryl diester phosphodiesterase
BM525_RS05410	COG0346	lactoylglutathione lyase activity
BM525_RS05415	COG1278	Cold shock
BM525_RS05430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BM525_RS05435	COG4660	Part of a membrane complex involved in electron transport
BM525_RS05440	COG4659	FMN binding
BM525_RS05445	COG4658	electron transport chain
BM525_RS05450	COG4656	Part of a membrane complex involved in electron transport
BM525_RS05455	COG2878	Part of a membrane complex involved in electron transport
BM525_RS05460	COG4657	Part of a membrane complex involved in electron transport
BM525_RS05475	COG0534	Mate efflux family protein
BM525_RS05480	COG0556	nucleotide-excision repair
BM525_RS05495	COG0602	queuosine metabolic process
BM525_RS05505	COG0367	asparagine synthase
BM525_RS05530	COG3273	potassium ion transport
BM525_RS05530	COG0471	metal ion transport
BM525_RS05545	COG0529	Catalyzes the synthesis of activated sulfate
BM525_RS05550	COG0175	sulfate reduction
BM525_RS05555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM525_RS05560	COG3706	GGDEF domain
BM525_RS05585	COG2304	oxidoreductase activity
BM525_RS05605	COG0714	Associated with various cellular activities
BM525_RS05615	COG1024	Enoyl-CoA hydratase
BM525_RS05615	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM525_RS05630	COG1025	Belongs to the peptidase M16 family
BM525_RS05635	COG2062	phosphohistidine phosphatase, SixA
BM525_RS05645	COG4536	flavin adenine dinucleotide binding
BM525_RS05650	COG4137	Cytochrome C assembly protein
BM525_RS05655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM525_RS05700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS05705	COG1132	(ABC) transporter
BM525_RS05720	COG0228	four-way junction DNA binding
BM525_RS05725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BM525_RS05730	COG0336	Belongs to the RNA methyltransferase TrmD family
BM525_RS05735	COG0335	large ribosomal subunit rRNA binding
BM525_RS05740	COG2860	membrane
BM525_RS05750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM525_RS05755	COG1605	Chorismate mutase
BM525_RS05755	COG0287	Prephenate dehydrogenase
BM525_RS05760	COG0077	Prephenate dehydratase
BM525_RS05760	COG1605	Chorismate mutase
BM525_RS05765	COG0745	RESPONSE REGULATOR receiver
BM525_RS05770	COG0023	Translation Initiation Factor
BM525_RS05800	COG2205	protein histidine kinase activity
BM525_RS05810	COG2204	response regulator
BM525_RS05835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BM525_RS05840	COG0494	nUDIX hydrolase
BM525_RS05845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BM525_RS05850	COG0632	four-way junction helicase activity
BM525_RS05855	COG2255	four-way junction helicase activity
BM525_RS05860	COG0824	Thioesterase
BM525_RS05865	COG0811	peptide transport
BM525_RS05880	COG0823	Involved in the tonB-independent uptake of proteins
BM525_RS05885	COG2885	chlorophyll binding
BM525_RS05890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BM525_RS05910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BM525_RS05925	COG4667	esterase of the alpha-beta hydrolase superfamily
BM525_RS05930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM525_RS05945	COG0300	oxidoreductase activity
BM525_RS05950	COG3038	cytochrome b561
BM525_RS05980	COG0583	DNA-binding transcription factor activity
BM525_RS05985	COG1064	alcohol dehydrogenase
BM525_RS05990	COG1451	nucleotide metabolic process
BM525_RS05995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM525_RS06005	COG1309	transcriptional regulator
BM525_RS06010	COG4774	siderophore transport
BM525_RS06030	COG3706	GGDEF domain
BM525_RS06040	COG3008	intermembrane lipid transfer
BM525_RS06040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM525_RS06045	COG2995	paraquat-inducible protein a
BM525_RS06065	COG2207	Transcriptional regulator
BM525_RS06070	COG0017	Asparaginyl-tRNA synthetase
BM525_RS06085	COG0189	ligase activity
BM525_RS06115	COG0156	8-amino-7-oxononanoate synthase activity
BM525_RS06120	COG2226	methyltransferase
BM525_RS06130	COG3340	Belongs to the peptidase S51 family
BM525_RS06135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BM525_RS06140	COG4139	cobalamin transport
BM525_RS06145	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BM525_RS06150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BM525_RS06165	COG5265	(ABC) transporter
BM525_RS06170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM525_RS06180	COG0745	RESPONSE REGULATOR receiver
BM525_RS06200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM525_RS06235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM525_RS06250	COG2755	lipolytic protein G-D-S-L family
BM525_RS06255	COG4181	ATPase activity
BM525_RS06260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BM525_RS06265	COG1090	epimerase
BM525_RS06270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM525_RS06275	COG0628	permease
BM525_RS06300	COG2350	Protein conserved in bacteria
BM525_RS06305	COG0159	tryptophan synthase activity
BM525_RS06315	COG0134	indole-3-glycerol-phosphate synthase activity
BM525_RS06315	COG0135	phosphoribosylanthranilate isomerase activity
BM525_RS06320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM525_RS06330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BM525_RS06335	COG0613	PHP domain protein
BM525_RS06340	COG0009	L-threonylcarbamoyladenylate synthase
BM525_RS06345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BM525_RS06350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BM525_RS06360	COG0656	L-ascorbic acid biosynthetic process
BM525_RS06365	COG0110	maltose O-acetyltransferase activity
BM525_RS06375	COG2733	membrane
BM525_RS06395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS06400	COG0500	methyltransferase
BM525_RS06405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM525_RS06410	COG0497	DNA recombination
BM525_RS06415	COG0783	Belongs to the Dps family
BM525_RS06420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BM525_RS06425	COG1454	alcohol dehydrogenase
BM525_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS06440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BM525_RS06445	COG2610	gluconate transmembrane transporter activity
BM525_RS06460	COG0784	Response regulator, receiver
BM525_RS06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS06460	COG2198	Histidine kinase
BM525_RS06460	COG2205	protein histidine kinase activity
BM525_RS06480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM525_RS06490	COG0484	heat shock protein binding
BM525_RS06495	COG3909	cytochrome
BM525_RS06515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BM525_RS06520	COG0505	Belongs to the CarA family
BM525_RS06525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BM525_RS06530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM525_RS06555	COG0857	belongs to the CobB CobQ family
BM525_RS06555	COG0280	phosphate acetyltransferase
BM525_RS06570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BM525_RS06575	COG4535	Mg2 and Co2 transporter CorC
BM525_RS06585	COG1702	phosphate starvation-inducible protein PhoH
BM525_RS06595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM525_RS06625	COG1607	acyl-coa hydrolase
BM525_RS06630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM525_RS06640	COG1115	amino acid carrier protein
BM525_RS06680	COG0012	GTP binding
BM525_RS06695	COG1064	alcohol dehydrogenase
BM525_RS06710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BM525_RS06720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BM525_RS06725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BM525_RS06730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BM525_RS06740	COG2890	protein-(glutamine-N5) methyltransferase activity
BM525_RS06745	COG0784	Response regulator, receiver
BM525_RS06745	COG3437	response regulator, receiver
BM525_RS06755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BM525_RS06765	COG0583	DNA-binding transcription factor activity
BM525_RS06775	COG2363	Small membrane protein
BM525_RS06790	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BM525_RS06795	COG0515	serine threonine protein kinase
BM525_RS06800	COG2116	formate transmembrane transporter activity
BM525_RS06815	COG0714	Associated with various cellular activities
BM525_RS06820	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BM525_RS06825	COG0033	Phosphoglucomutase
BM525_RS06830	COG0058	SHG alpha-glucan phosphorylase activity
BM525_RS06840	COG2988	succinylglutamate desuccinylase activity
BM525_RS06875	COG1393	Belongs to the ArsC family
BM525_RS06900	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BM525_RS06930	COG5001	Diguanylate cyclase
BM525_RS06930	COG3300	MHYT domain
BM525_RS06955	COG2249	NAD(P)H dehydrogenase (quinone) activity
BM525_RS06975	COG1733	regulation of RNA biosynthetic process
BM525_RS06980	COG3447	MASE1 domain protein
BM525_RS06980	COG5001	Diguanylate cyclase
BM525_RS06980	COG5002	protein histidine kinase activity
BM525_RS06990	COG0402	S-adenosylhomocysteine deaminase activity
BM525_RS06995	COG2351	hydroxyisourate hydrolase activity
BM525_RS07010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM525_RS07025	COG1309	transcriptional regulator
BM525_RS07040	COG2252	PERMEase
BM525_RS07045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BM525_RS07060	COG3706	GGDEF domain
BM525_RS07060	COG4251	negative regulation of phosphorylation
BM525_RS07060	COG2203	Gaf domain
BM525_RS07060	COG5001	Diguanylate cyclase
BM525_RS07065	COG2205	protein histidine kinase activity
BM525_RS07065	COG0784	Response regulator, receiver
BM525_RS07080	COG2233	PERMEase
BM525_RS07095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM525_RS07100	COG0730	response to heat
BM525_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS07145	COG3001	Fructosamine kinase
BM525_RS07155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BM525_RS07175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM525_RS07185	COG1596	polysaccharide export
BM525_RS07190	COG0489	protein tyrosine kinase activity
BM525_RS07195	COG4464	protein tyrosine phosphatase activity
BM525_RS07230	COG0297	glycogen (starch) synthase activity
BM525_RS07285	COG0438	transferase activity, transferring glycosyl groups
BM525_RS07295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BM525_RS07295	COG2755	lipolytic protein G-D-S-L family
BM525_RS07315	COG0072	phenylalanine-tRNA ligase activity
BM525_RS07315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM525_RS07340	COG1472	Belongs to the glycosyl hydrolase 3 family
BM525_RS07345	COG2096	Adenosyltransferase
BM525_RS07355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM525_RS07365	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM525_RS07390	COG0708	Exodeoxyribonuclease III
BM525_RS07425	COG2814	Major facilitator Superfamily
BM525_RS07460	COG4770	biotin carboxylase activity
BM525_RS07465	COG1024	Enoyl-CoA hydratase
BM525_RS07470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM525_RS07475	COG1960	acyl-CoA dehydrogenase activity
BM525_RS07480	COG0789	Transcriptional regulator
BM525_RS07485	COG0183	Belongs to the thiolase family
BM525_RS07500	COG3706	GGDEF domain
BM525_RS07510	COG2925	Exonuclease
BM525_RS07560	COG1643	Atp-dependent helicase
BM525_RS07580	COG3321	synthase
BM525_RS07580	COG0604	alcohol dehydrogenase
BM525_RS07585	COG0328	RNA-DNA hybrid ribonuclease activity
BM525_RS07590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM525_RS07610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BM525_RS07615	COG1136	(ABC) transporter
BM525_RS07620	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM525_RS07635	COG3724	N-succinylarginine dihydrolase activity
BM525_RS07645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BM525_RS07660	COG0746	molybdenum cofactor guanylyltransferase activity
BM525_RS07665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BM525_RS07670	COG0243	molybdopterin cofactor binding
BM525_RS07680	COG0625	glutathione transferase activity
BM525_RS07695	COG2153	protein acetylation
BM525_RS07710	COG1530	ribonuclease E activity
BM525_RS07730	COG1399	metal-binding, possibly nucleic acid-binding protein
BM525_RS07740	COG0416	fatty acid biosynthetic process
BM525_RS07745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BM525_RS07750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BM525_RS07760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM525_RS07765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM525_RS07775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BM525_RS07790	COG0084	hydrolase, TatD family'
BM525_RS07800	COG0702	epimerase
BM525_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS07830	COG0596	Alpha beta hydrolase
BM525_RS07840	COG0183	Belongs to the thiolase family
BM525_RS07845	COG1960	acyl-CoA dehydrogenase activity
BM525_RS07865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM525_RS07875	COG0246	Mannitol dehydrogenase
BM525_RS07900	COG0668	transmembrane transport
BM525_RS07905	COG4771	TonB-dependent receptor
BM525_RS07935	COG3437	response regulator, receiver
BM525_RS07945	COG0195	Participates in both transcription termination and antitermination
BM525_RS07960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BM525_RS07975	COG3300	MHYT domain
BM525_RS07975	COG5001	Diguanylate cyclase
BM525_RS07980	COG1187	pseudouridine synthase activity
BM525_RS07990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM525_RS07990	COG3153	acetyltransferase
BM525_RS08065	COG1032	radical SAM domain protein
BM525_RS08080	COG4771	TonB-dependent receptor
BM525_RS08085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM525_RS08095	COG4134	Bacterial extracellular solute-binding protein
BM525_RS08105	COG4136	ATPase activity
BM525_RS08110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BM525_RS08130	COG3706	GGDEF domain
BM525_RS08130	COG4251	negative regulation of phosphorylation
BM525_RS08130	COG5001	Diguanylate cyclase
BM525_RS08130	COG2203	Gaf domain
BM525_RS08150	COG0583	DNA-binding transcription factor activity
BM525_RS08170	COG1131	(ABC) transporter
BM525_RS08185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM525_RS08190	COG0385	Bile acid
BM525_RS08255	COG1902	pentaerythritol trinitrate reductase activity
BM525_RS08265	COG2867	negative regulation of translational initiation
BM525_RS08270	COG2914	Belongs to the UPF0125 (RnfH) family
BM525_RS08280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM525_RS08285	COG4771	TonB-dependent receptor
BM525_RS08290	COG0457	Tetratricopeptide repeat
BM525_RS08305	COG0574	Belongs to the PEP-utilizing enzyme family
BM525_RS08305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM525_RS08340	COG2850	peptidyl-arginine hydroxylation
BM525_RS08350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BM525_RS08355	COG2915	High frequency lysogenization protein hflD homolog
BM525_RS08360	COG0482	sulfurtransferase activity
BM525_RS08365	COG1187	pseudouridine synthase activity
BM525_RS08375	COG1278	Cold shock
BM525_RS08380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BM525_RS08385	COG0542	response to heat
BM525_RS08390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BM525_RS08395	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BM525_RS08400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BM525_RS08405	COG0492	ferredoxin-NADP+ reductase activity
BM525_RS08415	COG3091	SprT-like family
BM525_RS08420	COG0616	signal peptide processing
BM525_RS08435	COG0778	Nitroreductase
BM525_RS08445	COG0252	asparaginase activity
BM525_RS08450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BM525_RS08455	COG0321	lipoyl(octanoyl) transferase activity
BM525_RS08460	COG2921	Belongs to the UPF0250 family
BM525_RS08465	COG1686	Belongs to the peptidase S11 family
BM525_RS08470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM525_RS08475	COG0772	Belongs to the SEDS family
BM525_RS08480	COG0768	penicillin binding
BM525_RS08485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BM525_RS08490	COG0799	negative regulation of ribosome biogenesis
BM525_RS08500	COG1466	dna polymerase III delta subunit
BM525_RS08505	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BM525_RS08510	COG0495	leucyl-tRNA aminoacylation
BM525_RS08520	COG1067	ATP-dependent peptidase activity
BM525_RS08525	COG0596	Alpha beta hydrolase
BM525_RS08530	COG3706	GGDEF domain
BM525_RS08540	COG1534	Rna-binding protein
BM525_RS08545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BM525_RS08550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM525_RS08555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BM525_RS08560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM525_RS08565	COG0149	triose-phosphate isomerase activity
BM525_RS08570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM525_RS08580	COG5001	Diguanylate cyclase
BM525_RS08580	COG3300	MHYT domain
BM525_RS08600	COG1803	Methylglyoxal synthase
BM525_RS08600	COG1597	lipid kinase activity
BM525_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS08615	COG0561	phosphatase activity
BM525_RS08630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM525_RS08635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM525_RS08640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BM525_RS08655	COG1185	polyribonucleotide nucleotidyltransferase activity
BM525_RS08835	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BM525_RS08840	COG1196	nuclear chromosome segregation
BM525_RS08850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BM525_RS08865	COG1132	(ABC) transporter
BM525_RS08870	COG1663	tetraacyldisaccharide 4'-kinase activity
BM525_RS08905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BM525_RS08910	COG0435	Glutathione S-transferase
BM525_RS08915	COG1741	Belongs to the pirin family
BM525_RS08920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM525_RS08930	COG0372	Belongs to the citrate synthase family
BM525_RS08940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BM525_RS08945	COG1053	succinate dehydrogenase
BM525_RS08950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM525_RS08955	COG0567	Dehydrogenase, E1 component
BM525_RS08960	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM525_RS09010	COG4667	esterase of the alpha-beta hydrolase superfamily
BM525_RS09030	COG0366	Alpha amylase catalytic
BM525_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS09060	COG2267	carboxylic ester hydrolase activity
BM525_RS09070	COG0616	signal peptide processing
BM525_RS09090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM525_RS09095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM525_RS09100	COG0386	Belongs to the glutathione peroxidase family
BM525_RS09105	COG2084	Dehydrogenase
BM525_RS09115	COG1960	acyl-CoA dehydrogenase activity
BM525_RS09120	COG1024	Enoyl-CoA hydratase
BM525_RS09125	COG2226	methyltransferase
BM525_RS09130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM525_RS09135	COG3083	sulfuric ester hydrolase activity
BM525_RS09140	COG3082	Protein of unknown function (DUF1414)
BM525_RS09145	COG3081	Nucleoid-associated protein
BM525_RS09175	COG3275	phosphorelay sensor kinase activity
BM525_RS09180	COG3279	Response regulator of the LytR AlgR family
BM525_RS09185	COG0205	6-phosphofructokinase activity
BM525_RS09195	COG0789	Transcriptional regulator
BM525_RS09245	COG2205	protein histidine kinase activity
BM525_RS09245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS09255	COG1054	Belongs to the UPF0176 family
BM525_RS09265	COG0513	Belongs to the DEAD box helicase family
BM525_RS09275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BM525_RS09280	COG0583	DNA-binding transcription factor activity
BM525_RS09300	COG1760	l-serine dehydratase
BM525_RS09325	COG1322	Protein conserved in bacteria
BM525_RS09330	COG1404	Belongs to the peptidase S8 family
BM525_RS09335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BM525_RS09340	COG0022	dehydrogenase e1 component
BM525_RS09350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BM525_RS09355	COG0515	serine threonine protein kinase
BM525_RS09360	COG1946	Acyl-CoA thioesterase
BM525_RS09370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM525_RS09380	COG1956	GAF domain-containing protein
BM525_RS09395	COG0793	Belongs to the peptidase S41A family
BM525_RS09400	COG0733	neurotransmitter:sodium symporter activity
BM525_RS09405	COG1757	Na H antiporter
BM525_RS09410	COG0308	aminopeptidase N
BM525_RS09440	COG2902	Dehydrogenase
BM525_RS09445	COG0167	dihydroorotate dehydrogenase activity
BM525_RS09460	COG0488	(ABC) transporter
BM525_RS09470	COG3130	regulation of translation
BM525_RS09475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM525_RS09485	COG0415	Belongs to the DNA photolyase family
BM525_RS09490	COG0415	Belongs to the DNA photolyase family
BM525_RS09495	COG0415	Belongs to the DNA photolyase family
BM525_RS09500	COG3046	protein related to deoxyribodipyrimidine photolyase
BM525_RS09535	COG1082	Xylose isomerase domain protein TIM barrel
BM525_RS09565	COG4974	Belongs to the 'phage' integrase family
BM525_RS09575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BM525_RS09580	COG0589	response to stress
BM525_RS09590	COG0069	glutamate synthase activity
BM525_RS09605	COG2193	ferroxidase activity
BM525_RS09615	COG3278	Belongs to the heme-copper respiratory oxidase family
BM525_RS09630	COG2010	Cytochrome c
BM525_RS09655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM525_RS09660	COG0589	response to stress
BM525_RS09665	COG0037	tRNA processing
BM525_RS09670	COG1752	Esterase of the alpha-beta hydrolase superfamily
BM525_RS09690	COG1280	lysine exporter protein (LysE YggA)
BM525_RS09700	COG2897	thiosulfate sulfurtransferase activity
BM525_RS09705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BM525_RS09710	COG3148	PFAM DTW domain containing protein
BM525_RS09720	COG0670	Belongs to the BI1 family
BM525_RS09725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BM525_RS09740	COG2920	part of a sulfur-relay system
BM525_RS09770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BM525_RS09780	COG1674	ftsk spoiiie
BM525_RS09780	COG0531	amino acid
BM525_RS09790	COG0686	Belongs to the AlaDH PNT family
BM525_RS09795	COG0284	orotidine-5'-phosphate decarboxylase activity
BM525_RS09800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BM525_RS09815	COG0776	regulation of translation
BM525_RS09820	COG0539	negative regulation of cytoplasmic translation
BM525_RS09825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BM525_RS09830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM525_RS09835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM525_RS09845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM525_RS09850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM525_RS09855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM525_RS09860	COG0633	Ferredoxin
BM525_RS09890	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM525_RS09895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM525_RS09905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM525_RS09915	COG4783	chaperone-mediated protein folding
BM525_RS09925	COG1393	Belongs to the ArsC family
BM525_RS09940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM525_RS09955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM525_RS09965	COG1960	acyl-CoA dehydrogenase activity
BM525_RS09990	COG0572	uridine kinase
BM525_RS09995	COG3769	mannosylglycerate metabolic process
BM525_RS10000	COG1215	transferase activity, transferring glycosyl groups
BM525_RS10005	COG0366	Alpha amylase catalytic
BM525_RS10015	COG0303	'Molybdopterin
BM525_RS10020	COG0534	Mate efflux family protein
BM525_RS10035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM525_RS10040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM525_RS10100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM525_RS10135	COG3547	Transposase (IS116 IS110 IS902 family)
BM525_RS10235	COG0405	Gamma-glutamyltransferase
BM525_RS10240	COG1024	Enoyl-CoA hydratase
BM525_RS10285	COG1448	Aminotransferase
BM525_RS10300	COG1671	Belongs to the UPF0178 family
BM525_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS10315	COG1960	acyl-CoA dehydrogenase activity
BM525_RS10320	COG2207	Transcriptional regulator
BM525_RS10320	COG0662	Cupin 2, conserved barrel domain protein
BM525_RS10325	COG4771	TonB-dependent receptor
BM525_RS10335	COG1505	serine-type exopeptidase activity
BM525_RS10345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS10375	COG0596	Alpha beta hydrolase
BM525_RS10385	COG0716	FMN binding
BM525_RS10395	COG0735	belongs to the Fur family
BM525_RS10405	COG1984	allophanate hydrolase subunit 2
BM525_RS10410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BM525_RS10415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BM525_RS10420	COG2996	Protein conserved in bacteria
BM525_RS10425	COG1765	OsmC-like protein
BM525_RS10430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS10440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM525_RS10455	COG0436	Aminotransferase
BM525_RS10460	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM525_RS10465	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BM525_RS10490	COG3012	SEC-C Motif Domain Protein
BM525_RS10495	COG5001	Diguanylate cyclase
BM525_RS10495	COG3447	MASE1 domain protein
BM525_RS10495	COG5002	protein histidine kinase activity
BM525_RS10500	COG0366	Alpha amylase catalytic
BM525_RS10510	COG0604	alcohol dehydrogenase
BM525_RS10520	COG1960	acyl-CoA dehydrogenase activity
BM525_RS10530	COG4771	TonB-dependent receptor
BM525_RS10555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BM525_RS10575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BM525_RS10585	COG0521	Mo-molybdopterin cofactor biosynthetic process
BM525_RS10590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM525_RS10600	COG2161	toxin-antitoxin pair type II binding
BM525_RS10605	COG4115	mRNA cleavage
BM525_RS10620	COG0436	Aminotransferase
BM525_RS10625	COG3268	Saccharopine dehydrogenase
BM525_RS10630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM525_RS10655	COG4206	TonB-dependent receptor
BM525_RS10665	COG5006	permease, DMT superfamily
BM525_RS10680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM525_RS10685	COG1074	ATP-dependent DNA helicase activity
BM525_RS10690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BM525_RS10700	COG1022	Amp-dependent synthetase and ligase
BM525_RS10705	COG2203	Gaf domain
BM525_RS10705	COG3706	GGDEF domain
BM525_RS10705	COG4251	negative regulation of phosphorylation
BM525_RS10705	COG5001	Diguanylate cyclase
BM525_RS10725	COG0583	DNA-binding transcription factor activity
BM525_RS10740	COG0640	Transcriptional regulator
BM525_RS10760	COG2204	response regulator
BM525_RS10770	COG4251	negative regulation of phosphorylation
BM525_RS10775	COG0784	Response regulator, receiver
BM525_RS10780	COG2205	protein histidine kinase activity
BM525_RS10780	COG0784	Response regulator, receiver
BM525_RS10805	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM525_RS10830	COG3139	Protein of unknown function (DUF1315)
BM525_RS10845	COG1115	amino acid carrier protein
BM525_RS10850	COG2866	Carboxypeptidase
BM525_RS10870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BM525_RS10880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BM525_RS10885	COG1640	4-alpha-glucanotransferase
BM525_RS10890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BM525_RS10895	COG0676	glucose-6-phosphate 1-epimerase activity
BM525_RS10900	COG0800	Aldolase
BM525_RS10910	COG0129	dihydroxy-acid dehydratase activity
BM525_RS10920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BM525_RS10925	COG1737	Transcriptional regulator
BM525_RS10930	COG0469	pyruvate kinase activity
BM525_RS10935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM525_RS10950	COG2823	Periplasmic or secreted lipoprotein
BM525_RS10980	COG3665	Urea carboxylase-associated protein
BM525_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS11005	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BM525_RS11015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BM525_RS11030	COG2721	sulfolactate sulfo-lyase activity
BM525_RS11035	COG1904	glucuronate isomerase
BM525_RS11040	COG0246	Mannitol dehydrogenase
BM525_RS11045	COG0800	Aldolase
BM525_RS11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM525_RS11065	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BM525_RS11090	COG2356	endonuclease I
BM525_RS11095	COG0840	transmembrane signaling receptor activity
BM525_RS11110	COG0583	DNA-binding transcription factor activity
BM525_RS11115	COG1979	alcohol dehydrogenase
BM525_RS11120	COG5001	Diguanylate cyclase
BM525_RS11130	COG0784	Response regulator, receiver
BM525_RS11130	COG3437	response regulator, receiver
BM525_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS11135	COG4191	Histidine kinase
BM525_RS11155	COG0471	metal ion transport
BM525_RS11165	COG0489	protein tyrosine kinase activity
BM525_RS11170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM525_RS11170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM525_RS11175	COG0668	transmembrane transport
BM525_RS11180	COG2226	methyltransferase
BM525_RS11185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM525_RS11190	COG1388	LysM domain
BM525_RS11190	COG0741	lytic transglycosylase activity
BM525_RS11215	COG0215	cysteine-tRNA ligase activity
BM525_RS11220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM525_RS11225	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM525_RS11235	COG2268	Band 7 protein
BM525_RS11250	COG1733	regulation of RNA biosynthetic process
BM525_RS11255	COG0604	alcohol dehydrogenase
BM525_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS11270	COG0753	catalase activity
BM525_RS11275	COG0604	alcohol dehydrogenase
BM525_RS11280	COG0583	DNA-binding transcription factor activity
BM525_RS11315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BM525_RS11320	COG1286	toxin biosynthetic process
BM525_RS11325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BM525_RS11330	COG0285	dihydrofolate synthase activity
BM525_RS11350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BM525_RS11355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM525_RS11375	COG3609	addiction module antidote protein, CC2985 family
BM525_RS11380	COG0583	DNA-binding transcription factor activity
BM525_RS11385	COG0697	spore germination
BM525_RS11400	COG2080	2 iron, 2 sulfur cluster binding
BM525_RS11415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM525_RS11420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM525_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
BM525_RS11435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM525_RS11435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BM525_RS11470	COG0789	Transcriptional regulator
BM525_RS11475	COG0604	alcohol dehydrogenase
BM525_RS11500	COG1119	ATPase activity
BM525_RS11505	COG2031	fatty acid transporter
BM525_RS11510	COG5002	protein histidine kinase activity
BM525_RS11510	COG2205	protein histidine kinase activity
BM525_RS11510	COG0784	Response regulator, receiver
BM525_RS11520	COG0612	Peptidase, M16
BM525_RS11535	COG3101	peptidyl-lysine hydroxylation
BM525_RS11565	COG1902	pentaerythritol trinitrate reductase activity
BM525_RS11565	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM525_RS11590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM525_RS11600	COG4399	Belongs to the UPF0754 family
BM525_RS11625	COG1770	oligopeptidase
BM525_RS11630	COG2186	Transcriptional regulator
BM525_RS11640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BM525_RS11645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM525_RS11655	COG2983	Belongs to the UPF0260 family
BM525_RS11660	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM525_RS11675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BM525_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
BM525_RS11685	COG2267	carboxylic ester hydrolase activity
BM525_RS11700	COG1214	PFAM Peptidase M22, glycoprotease
BM525_RS11705	COG1199	ATP-dependent helicase activity
BM525_RS11755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BM525_RS11760	COG4771	TonB-dependent receptor
BM525_RS11770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BM525_RS11775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BM525_RS11780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM525_RS11785	COG0131	Imidazoleglycerol-phosphate dehydratase
BM525_RS11785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM525_RS11790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BM525_RS11810	COG2116	formate transmembrane transporter activity
BM525_RS11815	COG0840	transmembrane signaling receptor activity
BM525_RS11850	COG0326	Molecular chaperone. Has ATPase activity
BM525_RS11855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BM525_RS11935	COG0582	viral genome integration into host DNA
BM525_RS11955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BM525_RS11960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BM525_RS11970	COG3220	belongs to the UPF0276 family
BM525_RS11980	COG1136	(ABC) transporter
BM525_RS11980	COG0577	efflux transmembrane transporter activity
BM525_RS11990	COG2203	Gaf domain
BM525_RS11990	COG5001	Diguanylate cyclase
BM525_RS11990	COG4251	negative regulation of phosphorylation
BM525_RS11990	COG3706	GGDEF domain
BM525_RS12020	COG1183	phosphatidylcholine synthase activity
BM525_RS12040	COG0277	FAD linked oxidase domain protein
BM525_RS12045	COG0542	response to heat
BM525_RS12050	COG1496	oxidoreductase activity
BM525_RS12070	COG1595	DNA-templated transcription, initiation
BM525_RS12085	COG4221	oxidoreductase activity
BM525_RS12100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BM525_RS12110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BM525_RS12120	COG0142	geranyltranstransferase activity
BM525_RS12130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BM525_RS12135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BM525_RS12145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BM525_RS12160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM525_RS12160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM525_RS12175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM525_RS12180	COG0488	(ABC) transporter
BM525_RS12190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BM525_RS12200	COG0560	Phosphoserine phosphatase
BM525_RS12210	COG0084	hydrolase, TatD family'
BM525_RS12220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BM525_RS12225	COG0571	ribonuclease III activity
BM525_RS12255	COG1595	DNA-templated transcription, initiation
BM525_RS12260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BM525_RS12275	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BM525_RS12355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BM525_RS12360	COG1047	Peptidyl-prolyl cis-trans
BM525_RS12370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM525_RS12375	COG0196	riboflavin kinase activity
BM525_RS12380	COG0728	peptidoglycan biosynthetic process
BM525_RS12385	COG0268	Binds directly to 16S ribosomal RNA
BM525_RS12400	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS12405	COG0385	Bile acid
BM525_RS12410	COG0583	DNA-binding transcription factor activity
BM525_RS12435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM525_RS12440	COG0776	regulation of translation
BM525_RS12445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM525_RS12450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BM525_RS12455	COG0740	serine-type endopeptidase activity
BM525_RS12460	COG0544	peptidyl-prolyl cis-trans isomerase activity
BM525_RS12515	COG1720	tRNA m6t6A37 methyltransferase activity
BM525_RS12525	COG1234	tRNA 3'-trailer cleavage
BM525_RS12535	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM525_RS12550	COG0517	IMP dehydrogenase activity
BM525_RS12550	COG0516	GMP reductase activity
BM525_RS12555	COG1570	exodeoxyribonuclease VII activity
BM525_RS12575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM525_RS12580	COG2976	Protein conserved in bacteria
BM525_RS12605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BM525_RS12615	COG2166	iron-sulfur cluster assembly
BM525_RS12630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM525_RS12635	COG0719	Fe-S assembly protein
BM525_RS12640	COG0396	ATPase activity
BM525_RS12645	COG0719	Fe-S assembly protein
BM525_RS12650	COG1104	cysteine desulfurase activity
BM525_RS12655	COG1959	2 iron, 2 sulfur cluster binding
BM525_RS12660	COG2072	flavoprotein involved in K transport
BM525_RS12665	COG1045	serine acetyltransferase
BM525_RS12670	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BM525_RS12675	COG0483	inositol monophosphate 1-phosphatase activity
BM525_RS12690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM525_RS12695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM525_RS12700	COG1862	Preprotein translocase
BM525_RS12705	COG0343	queuine tRNA-ribosyltransferase activity
BM525_RS12725	COG1842	Phage shock protein A
BM525_RS12730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM525_RS12750	COG0754	glutathionylspermidine amidase activity
BM525_RS12780	COG2066	Belongs to the glutaminase family
BM525_RS12785	COG1785	Belongs to the alkaline phosphatase family
BM525_RS12790	COG0745	RESPONSE REGULATOR receiver
BM525_RS12875	COG0438	transferase activity, transferring glycosyl groups
BM525_RS12890	COG0367	asparagine synthase
BM525_RS12895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BM525_RS12895	COG2755	lipolytic protein G-D-S-L family
BM525_RS12900	COG0438	transferase activity, transferring glycosyl groups
BM525_RS12925	COG2244	polysaccharide biosynthetic process
BM525_RS12985	COG0489	protein tyrosine kinase activity
BM525_RS12995	COG3267	Type II secretory pathway component ExeA
BM525_RS12995	COG3409	Peptidoglycan-binding domain 1 protein
BM525_RS13000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM525_RS13000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM525_RS13030	COG1560	Kdo2-lipid A biosynthetic process
BM525_RS13045	COG1960	acyl-CoA dehydrogenase activity
BM525_RS13060	COG3300	MHYT domain
BM525_RS13060	COG5001	Diguanylate cyclase
BM525_RS13065	COG1435	thymidine kinase activity
BM525_RS13075	COG1609	Transcriptional regulator
BM525_RS13080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BM525_RS13110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BM525_RS13115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM525_RS13120	COG1024	Enoyl-CoA hydratase
BM525_RS13120	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM525_RS13135	COG1012	belongs to the aldehyde dehydrogenase family
BM525_RS13155	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BM525_RS13160	COG0789	Transcriptional regulator
BM525_RS13190	COG1960	acyl-CoA dehydrogenase activity
BM525_RS13215	COG0745	RESPONSE REGULATOR receiver
BM525_RS13220	COG2205	protein histidine kinase activity
BM525_RS13265	COG2080	2 iron, 2 sulfur cluster binding
BM525_RS13270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BM525_RS13275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM525_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
BM525_RS13300	COG4221	oxidoreductase activity
BM525_RS13305	COG0693	protein deglycase activity
BM525_RS13310	COG1295	ribonuclease BN
BM525_RS13355	COG2814	Major facilitator Superfamily
BM525_RS13375	COG0514	ATP-dependent DNA helicase (RecQ)
BM525_RS13400	COG3706	GGDEF domain
BM525_RS13415	COG4251	negative regulation of phosphorylation
BM525_RS13420	COG2133	pyrroloquinoline quinone binding
BM525_RS13450	COG3177	Filamentation induced by cAMP protein fic
BM525_RS13465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM525_RS13465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM525_RS13480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM525_RS13485	COG2971	BadF BadG BcrA BcrD
BM525_RS13490	COG0583	DNA-binding transcription factor activity
BM525_RS13495	COG1620	l-lactate permease
BM525_RS13520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM525_RS13525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM525_RS13530	COG0006	proline dipeptidase activity
BM525_RS13545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM525_RS13560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BM525_RS13565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BM525_RS13570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM525_RS13590	COG3313	Fe-S protein
BM525_RS13625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM525_RS13630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM525_RS13635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BM525_RS13650	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM525_RS13655	COG3577	Aspartyl protease
BM525_RS13660	COG0157	Belongs to the NadC ModD family
BM525_RS13665	COG4969	Belongs to the N-Me-Phe pilin family
BM525_RS13670	COG1459	type II secretion system
BM525_RS13675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM525_RS13680	COG0237	dephospho-CoA kinase activity
BM525_RS13680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM525_RS13685	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BM525_RS13690	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM525_RS13695	COG3608	succinylglutamate desuccinylase aspartoacylase
BM525_RS13710	COG0739	heme binding
BM525_RS13715	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BM525_RS13720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BM525_RS13725	COG0849	cell division
BM525_RS13730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BM525_RS13735	COG1181	Belongs to the D-alanine--D-alanine ligase family
BM525_RS13740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM525_RS13750	COG0772	Belongs to the SEDS family
BM525_RS13755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BM525_RS13765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BM525_RS13770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BM525_RS13775	COG0768	penicillin binding
BM525_RS13780	COG3116	cell division
BM525_RS13790	COG2001	Belongs to the MraZ family
BM525_RS13815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS13835	COG0678	peroxiredoxin activity
BM525_RS13835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM525_RS13860	COG2204	response regulator
BM525_RS13865	COG0784	Response regulator, receiver
BM525_RS13865	COG2205	protein histidine kinase activity
BM525_RS13880	COG2271	Major facilitator Superfamily
BM525_RS13905	COG0668	transmembrane transport
BM525_RS13910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BM525_RS13915	COG0189	ligase activity
BM525_RS13920	COG1678	Uncharacterized ACR, COG1678
BM525_RS13925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BM525_RS13950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BM525_RS13955	COG0762	integral membrane protein
BM525_RS13965	COG1902	pentaerythritol trinitrate reductase activity
BM525_RS13965	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM525_RS13980	COG0625	glutathione transferase activity
BM525_RS13990	COG1764	response to oxidative stress
BM525_RS13995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM525_RS14010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BM525_RS14015	COG1396	sequence-specific DNA binding
BM525_RS14020	COG2814	Major facilitator Superfamily
BM525_RS14025	COG0724	RNA recognition motif
BM525_RS14050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BM525_RS14055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BM525_RS14060	COG0083	homoserine kinase activity
BM525_RS14075	COG0583	DNA-binding transcription factor activity
BM525_RS14090	COG0640	Transcriptional regulator
BM525_RS14100	COG0431	NADPH-dependent FMN reductase
BM525_RS14105	COG0798	PFAM Bile acid sodium symporter
BM525_RS14110	COG2201	protein-glutamate methylesterase activity
BM525_RS14115	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BM525_RS14125	COG3850	Histidine kinase
BM525_RS14125	COG5002	protein histidine kinase activity
BM525_RS14140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BM525_RS14170	COG1748	Saccharopine dehydrogenase
BM525_RS14185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BM525_RS14190	COG3107	peptidoglycan biosynthetic process
BM525_RS14210	COG2823	Periplasmic or secreted lipoprotein
BM525_RS14230	COG4585	Histidine kinase
BM525_RS14235	COG2197	response regulator
BM525_RS14260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BM525_RS14265	COG0372	Belongs to the citrate synthase family
BM525_RS14270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BM525_RS14275	COG2828	Protein conserved in bacteria
BM525_RS14280	COG2199	diguanylate cyclase activity
BM525_RS14280	COG2203	Gaf domain
BM525_RS14300	COG5002	protein histidine kinase activity
BM525_RS14300	COG0784	Response regulator, receiver
BM525_RS14300	COG2198	Histidine kinase
BM525_RS14305	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM525_RS14310	COG0070	glutamate synthase
BM525_RS14310	COG0067	glutamate synthase
BM525_RS14310	COG0069	glutamate synthase activity
BM525_RS14315	COG0493	'glutamate synthase
BM525_RS14335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM525_RS14340	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BM525_RS14345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BM525_RS14350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM525_RS14365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM525_RS14370	COG5507	3-demethylubiquinone-9 3-methyltransferase
BM525_RS14375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BM525_RS14380	COG4942	peptidase
BM525_RS14385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BM525_RS14390	COG0738	Major facilitator superfamily
BM525_RS14420	COG0625	glutathione transferase activity
BM525_RS14445	COG2894	cell division
BM525_RS14450	COG0850	regulation of cytokinetic process
BM525_RS14460	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BM525_RS14480	COG1981	membrane
BM525_RS14495	COG1914	H( )-stimulated, divalent metal cation uptake system
BM525_RS14510	COG1217	gtp-binding protein TYPA
BM525_RS14515	COG0174	glutamine synthetase
BM525_RS14525	COG3852	Histidine kinase
BM525_RS14530	COG2204	response regulator
BM525_RS14535	COG3437	response regulator, receiver
BM525_RS14575	COG3437	response regulator, receiver
BM525_RS14575	COG3850	Histidine kinase
BM525_RS14575	COG4999	Histidine kinase
BM525_RS14575	COG2205	protein histidine kinase activity
BM525_RS14580	COG0525	valine-tRNA ligase activity
BM525_RS14585	COG2927	DNA polymerase III (CHI subunit)
BM525_RS14590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM525_RS14595	COG0795	lipopolysaccharide-transporting ATPase activity
BM525_RS14600	COG0795	lipopolysaccharide-transporting ATPase activity
BM525_RS14675	COG3459	Glycosyltransferase 36 associated
BM525_RS14685	COG2203	Gaf domain
BM525_RS14685	COG2199	diguanylate cyclase activity
BM525_RS14715	COG0673	inositol 2-dehydrogenase activity
BM525_RS14720	COG0784	Response regulator, receiver
BM525_RS14720	COG2205	protein histidine kinase activity
BM525_RS14720	COG2198	Histidine kinase
BM525_RS14720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM525_RS14725	COG0628	permease
BM525_RS14740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BM525_RS14745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BM525_RS14750	COG4558	Periplasmic binding protein
BM525_RS14760	COG4206	TonB-dependent receptor
BM525_RS14770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BM525_RS14795	COG4447	cellulose binding
BM525_RS14805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BM525_RS14815	COG0006	proline dipeptidase activity
BM525_RS14820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BM525_RS14830	COG0679	Auxin Efflux Carrier
BM525_RS14840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM525_RS14850	COG0395	ABC-type sugar transport system, permease component
BM525_RS14870	COG2267	carboxylic ester hydrolase activity
BM525_RS14900	COG1131	(ABC) transporter
BM525_RS14910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM525_RS14965	COG2205	protein histidine kinase activity
BM525_RS14975	COG3901	Regulator of nitric oxide reductase transcription
BM525_RS14975	COG0348	domain, Protein
BM525_RS14985	COG2197	response regulator
BM525_RS15020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM525_RS15025	COG0277	FAD linked oxidase domain protein
BM525_RS15035	COG1462	curli production assembly transport component CsgG
BM525_RS15065	COG2197	response regulator
BM525_RS15100	COG0513	Belongs to the DEAD box helicase family
BM525_RS15105	COG5001	Diguanylate cyclase
BM525_RS15115	COG0800	Aldolase
BM525_RS15120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM525_RS15135	COG3264	Mechanosensitive ion channel
BM525_RS15135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BM525_RS15175	COG0730	response to heat
BM525_RS15180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM525_RS15195	COG4191	Histidine kinase
BM525_RS15205	COG0417	DNA replication proofreading
BM525_RS15215	COG0318	PFAM AMP-dependent synthetase and ligase
BM525_RS15255	COG1309	transcriptional regulator
BM525_RS15265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM525_RS15275	COG1573	uracil-dna glycosylase
BM525_RS15280	COG3300	MHYT domain
BM525_RS15280	COG5001	Diguanylate cyclase
BM525_RS15300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM525_RS15320	COG1983	PspC domain protein
BM525_RS15325	COG1842	Phage shock protein A
BM525_RS15335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM525_RS15360	COG1621	beta-fructofuranosidase activity
BM525_RS15390	COG0438	transferase activity, transferring glycosyl groups
BM525_RS15420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM525_RS15430	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BM525_RS15435	COG0204	Acyl-transferase
BM525_RS15440	COG0204	Acyl-transferase
BM525_RS15445	COG0668	transmembrane transport
BM525_RS15460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM525_RS15465	COG0733	neurotransmitter:sodium symporter activity
BM525_RS15480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM525_RS15505	COG0848	biopolymer transport protein
BM525_RS15515	COG0457	Tetratricopeptide repeat
BM525_RS15520	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BM525_RS15530	COG1215	transferase activity, transferring glycosyl groups
BM525_RS15545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BM525_RS15550	COG0702	epimerase
BM525_RS15565	COG5001	Diguanylate cyclase
BM525_RS15565	COG5002	protein histidine kinase activity
BM525_RS15575	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BM525_RS15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM525_RS15595	COG0583	DNA-binding transcription factor activity
BM525_RS15600	COG0121	glutamine amidotransferase
BM525_RS15610	COG4682	membrane
BM525_RS15630	COG1953	Uracil, thiamine, allantoin
BM525_RS15635	COG4771	TonB-dependent receptor
BM525_RS15645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM525_RS15655	COG0596	Alpha beta hydrolase
BM525_RS15660	COG0251	oxidation-reduction process
BM525_RS15665	COG1335	isochorismatase
BM525_RS15670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM525_RS15675	COG1309	transcriptional regulator
BM525_RS15690	COG4628	conserved protein (DUF2132)
BM525_RS15710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BM525_RS15715	COG1609	Transcriptional regulator
BM525_RS15720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM525_RS15730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BM525_RS15750	COG1477	protein flavinylation
BM525_RS15755	COG2871	sodium ion transport
BM525_RS15760	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM525_RS15765	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM525_RS15770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM525_RS15775	COG1805	sodium ion transport
BM525_RS15780	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM525_RS15785	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BM525_RS15790	COG0545	Peptidyl-prolyl cis-trans isomerase
BM525_RS15795	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BM525_RS15810	COG0039	L-malate dehydrogenase activity
BM525_RS15815	COG1438	arginine binding
BM525_RS15840	COG0572	uridine kinase
BM525_RS15845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BM525_RS15870	COG2176	DNA-directed DNA polymerase activity
BM525_RS15880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM525_RS15890	COG2205	protein histidine kinase activity
BM525_RS15900	COG0189	ligase activity
BM525_RS15910	COG4067	protein conserved in archaea
BM525_RS15910	COG0189	ligase activity
BM525_RS15925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BM525_RS15935	COG1283	sodium-dependent phosphate transmembrane transporter activity
BM525_RS15940	COG0667	Aldo Keto reductase
BM525_RS15965	COG2815	serine threonine protein kinase
BM525_RS15965	COG0515	serine threonine protein kinase
BM525_RS16055	COG2274	protein secretion by the type I secretion system
BM525_RS16060	COG0583	DNA-binding transcription factor activity
BM525_RS16095	COG1216	Glycosyl transferase, family 2
BM525_RS16095	COG0438	transferase activity, transferring glycosyl groups
BM525_RS16105	COG1091	dTDP-4-dehydrorhamnose reductase activity
BM525_RS16125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM525_RS16165	COG0463	Glycosyl transferase, family 2
BM525_RS16170	COG2089	acid synthase
BM525_RS16185	COG1083	cytidylyl-transferase
BM525_RS16190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM525_RS16195	COG1086	Polysaccharide biosynthesis protein
BM525_RS16220	COG0202	RNA polymerase activity
BM525_RS16245	COG0201	protein transport
BM525_RS16265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BM525_RS16300	COG5002	protein histidine kinase activity
BM525_RS16300	COG0784	Response regulator, receiver
BM525_RS16315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM525_RS16320	COG0557	exoribonuclease II activity
BM525_RS16340	COG4771	TonB-dependent receptor
BM525_RS16355	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BM525_RS16380	COG2234	aminopeptidase activity
BM525_RS16390	COG4251	negative regulation of phosphorylation
BM525_RS16410	COG1271	oxidase subunit
BM525_RS16415	COG1294	oxidase, subunit
BM525_RS16420	COG1522	sequence-specific DNA binding
BM525_RS16430	COG1278	Cold shock
BM525_RS16435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM525_RS16455	COG0339	signal peptide processing
BM525_RS16460	COG2201	protein-glutamate methylesterase activity
BM525_RS16470	COG3852	Histidine kinase
BM525_RS16480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM525_RS16485	COG0243	molybdopterin cofactor binding
BM525_RS16490	COG4946	Tricorn protease homolog
BM525_RS16490	COG0823	Involved in the tonB-independent uptake of proteins
BM525_RS16490	COG1506	peptidase
BM525_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM525_RS16545	COG2197	response regulator
BM525_RS16575	COG1621	beta-fructofuranosidase activity
BM525_RS16580	COG2814	Major facilitator Superfamily
BM525_RS16585	COG0702	epimerase
BM525_RS16590	COG1629	transport
BM525_RS16600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BM525_RS16605	COG1278	Cold shock
BM525_RS16615	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM525_RS16620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BM525_RS16635	COG0281	malic enzyme
BM525_RS16645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BM525_RS16675	COG0456	acetyltransferase
BM525_RS16685	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM525_RS16690	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM525_RS16695	COG2177	Part of the ABC transporter FtsEX involved in
BM525_RS16700	COG2884	Cell division ATP-binding protein ftsE
BM525_RS16705	COG0552	protein localization to endoplasmic reticulum
BM525_RS16710	COG0742	ribosomal rna small subunit methyltransferase
BM525_RS16720	COG2095	MarC family integral membrane protein
BM525_RS16740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM525_RS16745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM525_RS16750	COG0617	tRNA 3'-terminal CCA addition
BM525_RS16755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM525_RS16770	COG0076	glutamate decarboxylase activity
BM525_RS16785	COG0842	Transport permease protein
BM525_RS16790	COG1131	(ABC) transporter
BM525_RS16795	COG0745	RESPONSE REGULATOR receiver
BM525_RS16800	COG2205	protein histidine kinase activity
BM525_RS16805	COG4774	siderophore transport
BM525_RS16830	COG1253	flavin adenine dinucleotide binding
BM525_RS16840	COG1966	Carbon starvation protein
BM525_RS16850	COG0657	acetylesterase activity
BM525_RS16870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BM525_RS16875	COG0049	tRNA binding
BM525_RS16880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BM525_RS16885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BM525_RS16890	COG0085	RNA polymerase activity
BM525_RS16895	COG0222	ribosome binding
BM525_RS16900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BM525_RS16905	COG0081	regulation of translation
BM525_RS16910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BM525_RS16930	COG0250	Participates in transcription elongation, termination and antitermination
BM525_RS16935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM525_RS16945	COG1132	(ABC) transporter
BM525_RS16950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BM525_RS16955	COG3590	peptidase
BM525_RS16965	COG0513	Belongs to the DEAD box helicase family
BM525_RS16970	COG0418	dihydroorotase activity
BM525_RS16975	COG3040	lipid binding
BM525_RS16980	COG4989	oxidoreductase activity
BM525_RS16985	COG0346	lactoylglutathione lyase activity
BM525_RS16990	COG0668	transmembrane transport
BM525_RS17010	COG0302	gtp cyclohydrolase
BM525_RS17020	COG2957	Belongs to the agmatine deiminase family
BM525_RS17025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM525_RS17035	COG1201	RNA secondary structure unwinding
BM525_RS17045	COG1793	dna ligase
BM525_RS17050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM525_RS17055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM525_RS17070	COG0625	glutathione transferase activity
BM525_RS17075	COG0625	glutathione transferase activity
BM525_RS17085	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BM525_RS17100	COG1012	belongs to the aldehyde dehydrogenase family
BM525_RS17105	COG0028	Belongs to the TPP enzyme family
BM525_RS17115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BM525_RS17120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BM525_RS17125	COG0330	HflC and HflK could
BM525_RS17130	COG0330	HflC and HflK could
BM525_RS17135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BM525_RS17140	COG1923	regulation of RNA biosynthetic process
BM525_RS17145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BM525_RS17160	COG0802	atpase or kinase
BM525_RS17165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BM525_RS17165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BM525_RS17170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BM525_RS17190	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BM525_RS17195	COG0735	belongs to the Fur family
BM525_RS17215	COG0305	Participates in initiation and elongation during chromosome replication
BM525_RS17240	COG2258	MOSC domain
BM525_RS17300	COG2205	protein histidine kinase activity
BM525_RS17300	COG0784	Response regulator, receiver
BM525_RS17300	COG2198	Histidine kinase
BM525_RS17310	COG1136	(ABC) transporter
BM525_RS17310	COG0577	efflux transmembrane transporter activity
BM525_RS17320	COG0840	transmembrane signaling receptor activity
BM525_RS17325	COG5002	protein histidine kinase activity
BM525_RS17330	COG0840	transmembrane signaling receptor activity
BM525_RS17345	COG2855	membrane
BM525_RS17350	COG2175	clavaminate synthase activity
BM525_RS17355	COG0656	L-ascorbic acid biosynthetic process
BM525_RS17360	COG2188	Transcriptional regulator
BM525_RS17370	COG1501	Belongs to the glycosyl hydrolase 31 family
BM525_RS17375	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM525_RS17380	COG4771	TonB-dependent receptor
BM525_RS17400	COG1757	Na H antiporter
BM525_RS17405	COG1472	Belongs to the glycosyl hydrolase 3 family
BM525_RS17415	COG2723	6-phospho-beta-galactosidase activity
BM525_RS17420	COG1609	Transcriptional regulator
BM525_RS17425	COG0477	Major facilitator Superfamily
BM525_RS17425	COG2814	Major facilitator Superfamily
BM525_RS17430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM525_RS17435	COG4988	ABC transporter
BM525_RS17440	COG4890	Cyd operon protein YbgT
BM525_RS17445	COG1294	oxidase, subunit
BM525_RS17485	COG4319	ketosteroid isomerase
BM525_RS17495	COG4771	TonB-dependent receptor
BM525_RS17510	COG1469	GTP cyclohydrolase I activity
BM525_RS17525	COG2375	cellular response to nickel ion
BM525_RS17530	COG3237	CsbD-like
BM525_RS17545	COG1595	DNA-templated transcription, initiation
BM525_RS17550	COG1404	Belongs to the peptidase S8 family
BM525_RS17575	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM525_RS17575	COG0596	Alpha beta hydrolase
BM525_RS17595	COG3038	cytochrome b561
BM525_RS17605	COG1252	NADH dehydrogenase
BM525_RS17620	COG0583	DNA-binding transcription factor activity
BM525_RS17625	COG2067	long-chain fatty acid transport protein
BM525_RS17630	COG2130	NADP-dependent
BM525_RS17635	COG2203	Gaf domain
BM525_RS17635	COG3706	GGDEF domain
BM525_RS17635	COG4251	negative regulation of phosphorylation
BM525_RS17635	COG5001	Diguanylate cyclase
BM525_RS17640	COG0784	Response regulator, receiver
BM525_RS17640	COG2205	protein histidine kinase activity
BM525_RS17650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM525_RS17655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM525_RS17660	COG1349	DNA-binding transcription factor activity
BM525_RS17665	COG0673	inositol 2-dehydrogenase activity
BM525_RS17680	COG0697	spore germination
BM525_RS17685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BM525_RS17690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BM525_RS17695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM525_RS17700	COG1166	arginine decarboxylase activity
BM525_RS17710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BM525_RS17770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM525_RS17795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BM525_RS17805	COG0328	RNA-DNA hybrid ribonuclease activity
BM525_RS17830	COG3030	protein affecting phage T7 exclusion by the F plasmid
BM525_RS17835	COG1324	tolerance protein
BM525_RS17840	COG4232	protein-disulfide reductase activity
BM525_RS17845	COG0739	heme binding
BM525_RS17850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM525_RS17855	COG0511	ligase activity, forming carbon-carbon bonds
BM525_RS17860	COG0439	Biotin carboxylase
BM525_RS17905	COG0154	amidase activity
BM525_RS17920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM525_RS17925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BM525_RS17940	COG0151	Belongs to the GarS family
BM525_RS17960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM525_RS17965	COG3954	Phosphoribulokinase
BM525_RS17990	COG1501	Belongs to the glycosyl hydrolase 31 family
BM525_RS18065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BM525_RS18070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BM525_RS18080	COG3031	protein transport across the cell outer membrane
BM525_RS18090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM525_RS18095	COG1459	type II secretion system
BM525_RS18100	COG2165	general secretion pathway protein
BM525_RS18105	COG2165	general secretion pathway protein
BM525_RS18110	COG2165	general secretion pathway protein
BM525_RS18115	COG4795	General secretion pathway protein
BM525_RS18130	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BM525_RS18145	COG1012	belongs to the aldehyde dehydrogenase family
BM525_RS18155	COG1011	Hydrolase
BM525_RS18160	COG0494	nUDIX hydrolase
BM525_RS18165	COG1218	3'(2'),5'-bisphosphate nucleotidase
BM525_RS18175	COG2943	transferase activity, transferring hexosyl groups
BM525_RS18180	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BM525_RS18190	COG3089	Belongs to the UPF0270 family
BM525_RS18195	COG0429	hydrolase of the alpha beta-hydrolase fold
BM525_RS18205	COG0488	(ABC) transporter
BM525_RS18230	COG0545	Peptidyl-prolyl cis-trans isomerase
BM525_RS18240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM525_RS18245	COG2183	response to ionizing radiation
BM525_RS18265	COG0596	Alpha beta hydrolase
BM525_RS18270	COG1040	competence protein
BM525_RS18290	COG1794	racemase activity, acting on amino acids and derivatives
BM525_RS18305	COG0534	Mate efflux family protein
BM525_RS18310	COG1649	PFAM Uncharacterised BCR, COG1649
BM525_RS18310	COG0726	polysaccharide deacetylase
BM525_RS18320	COG1999	signal sequence binding
BM525_RS18325	COG0109	protoheme IX farnesyltransferase activity
BM525_RS18330	COG1612	heme a metabolic process
BM525_RS18350	COG1845	cytochrome c oxidase, subunit III
BM525_RS18355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BM525_RS18360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BM525_RS18365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BM525_RS18385	COG0129	dihydroxy-acid dehydratase activity
BM525_RS18395	COG0606	chelatase, subunit chli
BM525_RS18410	COG2814	Major facilitator Superfamily
BM525_RS18415	COG1073	alpha beta
BM525_RS18420	COG0729	surface antigen
BM525_RS18425	COG2911	Protein conserved in bacteria
BM525_RS18450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM525_RS18460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM525_RS18480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM525_RS18505	COG1228	amidohydrolase
BM525_RS18530	COG0425	Belongs to the sulfur carrier protein TusA family
BM525_RS18545	COG1561	YicC-like family, N-terminal region
BM525_RS18565	COG2723	6-phospho-beta-galactosidase activity
BM525_RS18570	COG2211	Major facilitator Superfamily
BM525_RS18575	COG1609	Transcriptional regulator
BM525_RS18590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BM525_RS18590	COG2199	diguanylate cyclase activity
BM525_RS18615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BM525_RS18635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BM525_RS18640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BM525_RS18660	COG1475	DNA binding
BM525_RS18665	COG1192	Involved in chromosome partitioning
BM525_RS18690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM525_RS18695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BM525_RS18705	COG0706	membrane insertase activity
BM525_RS18710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BM525_RS18715	COG0594	ribonuclease P activity
BM525_RS18720	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BM525_RS18820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM525_RS18820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM525_RS19080	COG0210	DNA helicase
BM525_RS19245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM525_RS19290	COG1271	oxidase subunit
BM525_RS19600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BM525_RS19785	COG2081	HI0933 family
BM525_RS20055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM525_RS20955	COG1643	Atp-dependent helicase
BM525_RS21240	COG4796	Type ii and iii secretion system protein
BM525_RS21285	COG0281	malic enzyme
BM525_RS21685	COG0183	Belongs to the thiolase family
BM525_RS21695	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM525_RS21695	COG1024	Enoyl-CoA hydratase