locus-tag	class	description
AMAD1_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMAD1_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMAD1_RS00045	COG2818	Glycosylase
AMAD1_RS00055	COG3078	GTPase activator activity
AMAD1_RS00075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMAD1_RS00075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMAD1_RS00080	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AMAD1_RS00085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMAD1_RS00090	COG0569	domain protein
AMAD1_RS00095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMAD1_RS00095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMAD1_RS00100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMAD1_RS00115	COG0758	DNA mediated transformation
AMAD1_RS00130	COG0009	L-threonylcarbamoyladenylate synthase
AMAD1_RS00135	COG0408	coproporphyrinogen oxidase activity
AMAD1_RS00140	COG3047	cAMP biosynthetic process
AMAD1_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMAD1_RS00230	COG2234	aminopeptidase activity
AMAD1_RS00235	COG0463	Glycosyl transferase, family 2
AMAD1_RS00245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMAD1_RS00270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMAD1_RS00300	COG3642	lipopolysaccharide core region biosynthetic process
AMAD1_RS00305	COG0859	PFAM glycosyl transferase family 9
AMAD1_RS00335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMAD1_RS00350	COG3161	chorismate lyase activity
AMAD1_RS00355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMAD1_RS00375	COG0210	DNA helicase
AMAD1_RS00405	COG1757	Na H antiporter
AMAD1_RS00420	COG1959	2 iron, 2 sulfur cluster binding
AMAD1_RS00425	COG0730	response to heat
AMAD1_RS00440	COG4771	TonB-dependent receptor
AMAD1_RS00455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMAD1_RS00460	COG4988	ABC transporter
AMAD1_RS00470	COG1271	oxidase subunit
AMAD1_RS00480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMAD1_RS00480	COG0425	Belongs to the sulfur carrier protein TusA family
AMAD1_RS00490	COG0450	alkyl hydroperoxide reductase
AMAD1_RS00500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMAD1_RS00530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMAD1_RS00575	COG0270	DNA (cytosine-5-)-methyltransferase activity
AMAD1_RS00580	COG0556	nucleotide-excision repair
AMAD1_RS00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS00595	COG1129	ABC transporter
AMAD1_RS00595	COG0842	Transport permease protein
AMAD1_RS00600	COG0842	Transport permease protein
AMAD1_RS00615	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS00620	COG0583	DNA-binding transcription factor activity
AMAD1_RS00630	COG3106	COG3106 Predicted ATPase
AMAD1_RS00645	COG2184	nucleotidyltransferase activity
AMAD1_RS00650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMAD1_RS00665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMAD1_RS00670	COG0352	thiamine-phosphate diphosphorylase activity
AMAD1_RS00680	COG3071	HemY protein
AMAD1_RS00685	COG2959	enzyme of heme biosynthesis
AMAD1_RS00695	COG0181	hydroxymethylbilane synthase activity
AMAD1_RS00710	COG0194	GDP metabolic process
AMAD1_RS00720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMAD1_RS00730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMAD1_RS00735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMAD1_RS00745	COG0678	peroxiredoxin activity
AMAD1_RS00765	COG1178	ABC-type Fe3 transport system permease component
AMAD1_RS00770	COG3842	ATPase activity
AMAD1_RS00775	COG0668	transmembrane transport
AMAD1_RS00780	COG2081	HI0933 family
AMAD1_RS00795	COG2963	transposase activity
AMAD1_RS00830	COG0789	Transcriptional regulator
AMAD1_RS00835	COG2963	transposase activity
AMAD1_RS00840	COG2801	Transposase and inactivated derivatives
AMAD1_RS00855	COG2200	EAL domain
AMAD1_RS00860	COG0583	DNA-binding transcription factor activity
AMAD1_RS00885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS00900	COG0427	acetyl-CoA hydrolase
AMAD1_RS00905	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMAD1_RS00920	COG0840	transmembrane signaling receptor activity
AMAD1_RS00930	COG3064	Membrane
AMAD1_RS00940	COG5002	protein histidine kinase activity
AMAD1_RS00940	COG5001	Diguanylate cyclase
AMAD1_RS00955	COG0514	ATP-dependent DNA helicase (RecQ)
AMAD1_RS00960	COG2239	Acts as a magnesium transporter
AMAD1_RS00965	COG2962	Rard protein
AMAD1_RS00975	COG0210	DNA helicase
AMAD1_RS00985	COG1011	Hydrolase
AMAD1_RS00990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AMAD1_RS01000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMAD1_RS01005	COG0019	diaminopimelate decarboxylase activity
AMAD1_RS01035	COG0163	prenyltransferase activity
AMAD1_RS01040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMAD1_RS01050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMAD1_RS01070	COG1077	Cell shape determining protein MreB Mrl
AMAD1_RS01080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMAD1_RS01085	COG2814	Major facilitator Superfamily
AMAD1_RS01090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMAD1_RS01115	COG1085	galactose-1-phosphate uridylyltransferase
AMAD1_RS01120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMAD1_RS01130	COG0629	single-stranded DNA binding
AMAD1_RS01145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMAD1_RS01150	COG3250	beta-galactosidase activity
AMAD1_RS01170	COG1349	DNA-binding transcription factor activity
AMAD1_RS01215	COG3409	Peptidoglycan-binding domain 1 protein
AMAD1_RS01215	COG3267	Type II secretory pathway component ExeA
AMAD1_RS01225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMAD1_RS01230	COG1459	type II secretion system
AMAD1_RS01240	COG2165	general secretion pathway protein
AMAD1_RS01245	COG2165	general secretion pathway protein
AMAD1_RS01275	COG1077	Cell shape determining protein MreB Mrl
AMAD1_RS01280	COG1792	Involved in formation and maintenance of cell shape
AMAD1_RS01285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AMAD1_RS01295	COG1530	ribonuclease E activity
AMAD1_RS01305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMAD1_RS01310	COG0312	modulator of DNA gyrase
AMAD1_RS01315	COG3028	Belongs to the UPF0307 family
AMAD1_RS01320	COG0312	modulator of DNA gyrase
AMAD1_RS01330	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMAD1_RS01335	COG4191	Histidine kinase
AMAD1_RS01340	COG0297	glycogen (starch) synthase activity
AMAD1_RS01350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMAD1_RS01355	COG0596	Alpha beta hydrolase
AMAD1_RS01380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMAD1_RS01385	COG5002	protein histidine kinase activity
AMAD1_RS01390	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS01410	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMAD1_RS01475	COG1017	nitric oxide dioxygenase activity
AMAD1_RS01475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMAD1_RS01495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMAD1_RS01525	COG0375	protein maturation
AMAD1_RS01535	COG0409	Hydrogenase expression formation protein
AMAD1_RS01545	COG0309	Hydrogenase expression formation protein (HypE)
AMAD1_RS01550	COG0789	Transcriptional regulator
AMAD1_RS01555	COG2217	Heavy metal translocating P-type atpase
AMAD1_RS01640	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMAD1_RS01650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMAD1_RS01660	COG0463	Glycosyl transferase, family 2
AMAD1_RS01665	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS01670	COG5002	protein histidine kinase activity
AMAD1_RS01700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMAD1_RS01710	COG0789	Transcriptional regulator
AMAD1_RS01715	COG2217	Heavy metal translocating P-type atpase
AMAD1_RS01750	COG0531	amino acid
AMAD1_RS01820	COG2801	Transposase and inactivated derivatives
AMAD1_RS01895	COG1609	Transcriptional regulator
AMAD1_RS01900	COG0673	inositol 2-dehydrogenase activity
AMAD1_RS01910	COG2211	Major facilitator Superfamily
AMAD1_RS01935	COG1454	alcohol dehydrogenase
AMAD1_RS01990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMAD1_RS02010	COG0089	rRNA binding
AMAD1_RS02020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMAD1_RS02030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMAD1_RS02045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMAD1_RS02050	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS02060	COG1519	Transferase
AMAD1_RS02095	COG0788	formyltetrahydrofolate deformylase activity
AMAD1_RS02105	COG1643	Atp-dependent helicase
AMAD1_RS02110	COG2951	lytic endotransglycosylase activity
AMAD1_RS02115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMAD1_RS02125	COG2354	Protein conserved in bacteria
AMAD1_RS02145	COG0004	ammonium transporteR
AMAD1_RS02150	COG0405	Gamma-glutamyltransferase
AMAD1_RS02155	COG2837	iron assimilation
AMAD1_RS02170	COG0540	Belongs to the ATCase OTCase family
AMAD1_RS02195	COG2205	protein histidine kinase activity
AMAD1_RS02195	COG0784	Response regulator, receiver
AMAD1_RS02195	COG5002	protein histidine kinase activity
AMAD1_RS02210	COG3300	MHYT domain
AMAD1_RS02210	COG5001	Diguanylate cyclase
AMAD1_RS02220	COG1012	belongs to the aldehyde dehydrogenase family
AMAD1_RS02230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMAD1_RS02245	COG0180	Tryptophanyl-tRNA synthetase
AMAD1_RS02250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMAD1_RS02270	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AMAD1_RS02280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMAD1_RS02315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMAD1_RS02320	COG0281	malic enzyme
AMAD1_RS02330	COG0625	glutathione transferase activity
AMAD1_RS02340	COG0753	catalase activity
AMAD1_RS02355	COG3300	MHYT domain
AMAD1_RS02355	COG5001	Diguanylate cyclase
AMAD1_RS02360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMAD1_RS02360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMAD1_RS02370	COG0137	argininosuccinate synthase activity
AMAD1_RS02390	COG1803	Methylglyoxal synthase
AMAD1_RS02400	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS02405	COG2205	protein histidine kinase activity
AMAD1_RS02410	COG2267	carboxylic ester hydrolase activity
AMAD1_RS02415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMAD1_RS02425	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMAD1_RS02435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMAD1_RS02440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMAD1_RS02445	COG4942	peptidase
AMAD1_RS02450	COG2861	carbohydrate metabolic process
AMAD1_RS02475	COG1162	GTPase activity
AMAD1_RS02480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMAD1_RS02510	COG0028	Belongs to the TPP enzyme family
AMAD1_RS02530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMAD1_RS02535	COG0805	protein transport
AMAD1_RS02545	COG0084	hydrolase, TatD family'
AMAD1_RS02550	COG4251	negative regulation of phosphorylation
AMAD1_RS02550	COG3706	GGDEF domain
AMAD1_RS02550	COG2203	Gaf domain
AMAD1_RS02550	COG5001	Diguanylate cyclase
AMAD1_RS02560	COG0248	Ppx GppA phosphatase
AMAD1_RS02565	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS02570	COG3118	belongs to the thioredoxin family
AMAD1_RS02575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMAD1_RS02580	COG1473	amidohydrolase
AMAD1_RS02585	COG5002	protein histidine kinase activity
AMAD1_RS02585	COG0784	Response regulator, receiver
AMAD1_RS02590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMAD1_RS02595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMAD1_RS02600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMAD1_RS02615	COG0783	Belongs to the Dps family
AMAD1_RS02620	COG2133	pyrroloquinoline quinone binding
AMAD1_RS02625	COG1506	peptidase
AMAD1_RS02625	COG4946	Tricorn protease homolog
AMAD1_RS02625	COG0823	Involved in the tonB-independent uptake of proteins
AMAD1_RS02635	COG3118	belongs to the thioredoxin family
AMAD1_RS02650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AMAD1_RS02660	COG1012	belongs to the aldehyde dehydrogenase family
AMAD1_RS02680	COG1757	Na H antiporter
AMAD1_RS02695	COG3876	Protein conserved in bacteria
AMAD1_RS02700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AMAD1_RS02710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AMAD1_RS02720	COG0346	lactoylglutathione lyase activity
AMAD1_RS02745	COG2824	Alkylphosphonate utilization operon protein PhnA
AMAD1_RS02750	COG0454	-acetyltransferase
AMAD1_RS02780	COG3093	addiction module antidote protein HigA
AMAD1_RS02795	COG2026	Addiction module toxin, RelE StbE family
AMAD1_RS02820	COG3547	Transposase (IS116 IS110 IS902 family)
AMAD1_RS02865	COG2801	Transposase and inactivated derivatives
AMAD1_RS02875	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMAD1_RS02880	COG1620	l-lactate permease
AMAD1_RS02895	COG0514	ATP-dependent DNA helicase (RecQ)
AMAD1_RS02915	COG0183	Belongs to the thiolase family
AMAD1_RS02920	COG1024	Enoyl-CoA hydratase
AMAD1_RS02920	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMAD1_RS02930	COG0006	proline dipeptidase activity
AMAD1_RS02940	COG0142	geranyltranstransferase activity
AMAD1_RS02970	COG1388	LysM domain
AMAD1_RS02970	COG4942	peptidase
AMAD1_RS02975	COG1238	metal cluster binding
AMAD1_RS02985	COG0585	pseudouridine synthase activity
AMAD1_RS02990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMAD1_RS03000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMAD1_RS03010	COG0840	transmembrane signaling receptor activity
AMAD1_RS03045	COG0494	nUDIX hydrolase
AMAD1_RS03050	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AMAD1_RS03055	COG0730	response to heat
AMAD1_RS03060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMAD1_RS03065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMAD1_RS03100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMAD1_RS03110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMAD1_RS03120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMAD1_RS03120	COG1648	precorrin-2 dehydrogenase activity
AMAD1_RS03125	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS03140	COG1538	Outer membrane efflux protein
AMAD1_RS03145	COG0494	nUDIX hydrolase
AMAD1_RS03155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMAD1_RS03160	COG3150	esterase
AMAD1_RS03165	COG0187	DNA topoisomerase II activity
AMAD1_RS03175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMAD1_RS03200	COG1509	lysine 2,3-aminomutase activity
AMAD1_RS03205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMAD1_RS03210	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AMAD1_RS03225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMAD1_RS03240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMAD1_RS03255	COG0271	Belongs to the BolA IbaG family
AMAD1_RS03270	COG3707	response regulator
AMAD1_RS03285	COG0659	secondary active sulfate transmembrane transporter activity
AMAD1_RS03290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMAD1_RS03300	COG0243	molybdopterin cofactor binding
AMAD1_RS03305	COG1648	precorrin-2 dehydrogenase activity
AMAD1_RS03305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMAD1_RS03310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMAD1_RS03320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMAD1_RS03320	COG1116	anion transmembrane transporter activity
AMAD1_RS03330	COG1116	anion transmembrane transporter activity
AMAD1_RS03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMAD1_RS03350	COG4206	TonB-dependent receptor
AMAD1_RS03360	COG0348	domain, Protein
AMAD1_RS03375	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS03390	COG4948	Mandelate Racemase Muconate Lactonizing
AMAD1_RS03405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS03410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMAD1_RS03435	COG0358	DNA primase activity
AMAD1_RS03460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMAD1_RS03465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMAD1_RS03480	COG0537	adenosine 5'-monophosphoramidase activity
AMAD1_RS03495	COG3135	benzoate transporter
AMAD1_RS03500	COG1396	sequence-specific DNA binding
AMAD1_RS03505	COG2974	May be involved in recombination
AMAD1_RS03510	COG4191	Histidine kinase
AMAD1_RS03510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMAD1_RS03515	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS03520	COG5002	protein histidine kinase activity
AMAD1_RS03545	COG0811	peptide transport
AMAD1_RS03550	COG0811	peptide transport
AMAD1_RS03555	COG0848	biopolymer transport protein
AMAD1_RS03560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AMAD1_RS03570	COG3437	response regulator, receiver
AMAD1_RS03590	COG2133	pyrroloquinoline quinone binding
AMAD1_RS03600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMAD1_RS03625	COG0527	aspartate kinase activity
AMAD1_RS03630	COG0840	transmembrane signaling receptor activity
AMAD1_RS03635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMAD1_RS03640	COG2967	ApaG domain
AMAD1_RS03650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMAD1_RS03655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMAD1_RS03660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMAD1_RS03665	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMAD1_RS03675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMAD1_RS03695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMAD1_RS03710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMAD1_RS03715	COG3956	TIGRFAM MazG family protein
AMAD1_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS03750	COG0318	PFAM AMP-dependent synthetase and ligase
AMAD1_RS03760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMAD1_RS03770	COG0463	Glycosyl transferase, family 2
AMAD1_RS03790	COG0642	Histidine kinase
AMAD1_RS03810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMAD1_RS03815	COG0723	plastoquinol--plastocyanin reductase activity
AMAD1_RS03820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMAD1_RS03825	COG2857	Cytochrome c1
AMAD1_RS03830	COG0625	glutathione transferase activity
AMAD1_RS03835	COG2969	positive regulation of protein catabolic process
AMAD1_RS03840	COG2239	Acts as a magnesium transporter
AMAD1_RS03845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMAD1_RS03865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AMAD1_RS03870	COG1137	ATPase activity
AMAD1_RS03875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMAD1_RS03885	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMAD1_RS03900	COG1127	ABC transporter
AMAD1_RS03905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMAD1_RS03910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMAD1_RS03915	COG2854	intermembrane phospholipid transfer
AMAD1_RS03925	COG5007	Belongs to the BolA IbaG family
AMAD1_RS03935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMAD1_RS03940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMAD1_RS03950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMAD1_RS03985	COG4771	TonB-dependent receptor
AMAD1_RS03990	COG0697	spore germination
AMAD1_RS04000	COG0784	Response regulator, receiver
AMAD1_RS04000	COG2205	protein histidine kinase activity
AMAD1_RS04025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMAD1_RS04035	COG0126	phosphoglycerate kinase activity
AMAD1_RS04040	COG3588	fructose-bisphosphate aldolase
AMAD1_RS04050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS04060	COG1538	Outer membrane efflux protein
AMAD1_RS04065	COG4946	Tricorn protease homolog
AMAD1_RS04065	COG0823	Involved in the tonB-independent uptake of proteins
AMAD1_RS04065	COG1506	peptidase
AMAD1_RS04070	COG0248	Ppx GppA phosphatase
AMAD1_RS04075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMAD1_RS04085	COG0573	inorganic phosphate transmembrane transporter activity
AMAD1_RS04095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMAD1_RS04105	COG0306	phosphate transporter
AMAD1_RS04115	COG0583	DNA-binding transcription factor activity
AMAD1_RS04125	COG1272	protein, Hemolysin III
AMAD1_RS04130	COG1846	Transcriptional regulator
AMAD1_RS04135	COG1764	response to oxidative stress
AMAD1_RS04150	COG1739	Uncharacterized protein family UPF0029
AMAD1_RS04170	COG0420	3'-5' exonuclease activity
AMAD1_RS04175	COG0419	ATPase involved in DNA repair
AMAD1_RS04185	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AMAD1_RS04200	COG2188	Transcriptional regulator
AMAD1_RS04205	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMAD1_RS04210	COG2986	histidine ammonia-lyase
AMAD1_RS04235	COG0488	(ABC) transporter
AMAD1_RS04255	COG0668	transmembrane transport
AMAD1_RS04275	COG2801	Transposase and inactivated derivatives
AMAD1_RS04290	COG0582	viral genome integration into host DNA
AMAD1_RS04295	COG4372	Transposase
AMAD1_RS04345	COG1484	DNA-dependent DNA replication
AMAD1_RS04355	COG2801	Transposase and inactivated derivatives
AMAD1_RS04365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMAD1_RS04385	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AMAD1_RS04435	COG1346	cytolysis
AMAD1_RS04465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMAD1_RS04475	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS04485	COG3267	Type II secretory pathway component ExeA
AMAD1_RS04485	COG3409	Peptidoglycan-binding domain 1 protein
AMAD1_RS04500	COG0066	3-isopropylmalate dehydratase activity
AMAD1_RS04510	COG0473	3-isopropylmalate dehydrogenase activity
AMAD1_RS04515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMAD1_RS04535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMAD1_RS04550	COG4555	ABC transporter
AMAD1_RS04555	COG1668	transmembrane transport
AMAD1_RS04570	COG4133	protoheme IX ABC transporter activity
AMAD1_RS04575	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMAD1_RS04580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMAD1_RS04585	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMAD1_RS04595	COG1138	Cytochrome C-type biogenesis protein
AMAD1_RS04600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMAD1_RS04615	COG2853	Lipoprotein
AMAD1_RS04620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMAD1_RS04660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMAD1_RS04675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMAD1_RS04680	COG1596	polysaccharide export
AMAD1_RS04680	COG1555	photosystem II stabilization
AMAD1_RS04685	COG0473	3-isopropylmalate dehydrogenase activity
AMAD1_RS04700	COG1611	Belongs to the LOG family
AMAD1_RS04710	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMAD1_RS04710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMAD1_RS04765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMAD1_RS04770	COG0024	Methionine aminopeptidase
AMAD1_RS04775	COG0052	Belongs to the universal ribosomal protein uS2 family
AMAD1_RS04785	COG0528	UMP kinase activity
AMAD1_RS04800	COG0575	Belongs to the CDS family
AMAD1_RS04825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMAD1_RS04830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMAD1_RS04845	COG0587	DNA-directed DNA polymerase activity
AMAD1_RS04850	COG0825	malonyl-CoA metabolic process
AMAD1_RS04855	COG0037	tRNA processing
AMAD1_RS04885	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMAD1_RS04885	COG0047	phosphoribosylformylglycinamidine synthase activity
AMAD1_RS04890	COG2840	Smr protein MutS2
AMAD1_RS04920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS04925	COG2197	response regulator
AMAD1_RS04960	COG0784	Response regulator, receiver
AMAD1_RS04960	COG0835	chemotaxis
AMAD1_RS04965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMAD1_RS04970	COG1815	bacterial-type flagellum-dependent cell motility
AMAD1_RS04990	COG4787	bacterial-type flagellum-dependent cell motility
AMAD1_RS05010	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMAD1_RS05010	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMAD1_RS05015	COG1256	bacterial-type flagellum assembly
AMAD1_RS05030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMAD1_RS05035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMAD1_RS05040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMAD1_RS05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMAD1_RS05060	COG1516	flagellar protein fliS
AMAD1_RS05075	COG1086	Polysaccharide biosynthesis protein
AMAD1_RS05080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMAD1_RS05090	COG2089	acid synthase
AMAD1_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS05155	COG1660	Displays ATPase and GTPase activities
AMAD1_RS05160	COG1216	Glycosyl transferase, family 2
AMAD1_RS05175	COG1083	cytidylyl-transferase
AMAD1_RS05200	COG1677	Flagellar hook-basal body complex protein FliE
AMAD1_RS05205	COG1766	The M ring may be actively involved in energy transduction
AMAD1_RS05210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMAD1_RS05260	COG1987	bacterial-type flagellum assembly
AMAD1_RS05275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMAD1_RS05300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AMAD1_RS05305	COG0784	Response regulator, receiver
AMAD1_RS05305	COG0643	Histidine kinase
AMAD1_RS05305	COG2198	Histidine kinase
AMAD1_RS05315	COG1192	Involved in chromosome partitioning
AMAD1_RS05325	COG0835	chemotaxis
AMAD1_RS05340	COG0646	methionine synthase
AMAD1_RS05340	COG1410	methionine synthase
AMAD1_RS05345	COG1410	methionine synthase
AMAD1_RS05345	COG0646	methionine synthase
AMAD1_RS05355	COG3123	guanosine phosphorylase activity
AMAD1_RS05360	COG0583	DNA-binding transcription factor activity
AMAD1_RS05365	COG0583	DNA-binding transcription factor activity
AMAD1_RS05375	COG0659	secondary active sulfate transmembrane transporter activity
AMAD1_RS05390	COG3590	peptidase
AMAD1_RS05400	COG2137	regulation of response to DNA damage stimulus
AMAD1_RS05405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMAD1_RS05435	COG5016	pyruvate
AMAD1_RS05435	COG0511	ligase activity, forming carbon-carbon bonds
AMAD1_RS05440	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AMAD1_RS05445	COG4172	Belongs to the ABC transporter superfamily
AMAD1_RS05455	COG4171	peptide transport system, permease
AMAD1_RS05460	COG4168	peptide transport system, permease
AMAD1_RS05465	COG0747	negative chemotaxis
AMAD1_RS05470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMAD1_RS05475	COG1842	Phage shock protein A
AMAD1_RS05505	COG0625	glutathione transferase activity
AMAD1_RS05510	COG1522	sequence-specific DNA binding
AMAD1_RS05570	COG0811	peptide transport
AMAD1_RS05575	COG0811	peptide transport
AMAD1_RS05580	COG0848	biopolymer transport protein
AMAD1_RS05595	COG1444	tRNA N-acetyltransferase activity
AMAD1_RS05635	COG0456	acetyltransferase
AMAD1_RS05650	COG0583	DNA-binding transcription factor activity
AMAD1_RS05655	COG2814	Major facilitator Superfamily
AMAD1_RS05660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMAD1_RS05665	COG0656	L-ascorbic acid biosynthetic process
AMAD1_RS05685	COG1846	Transcriptional regulator
AMAD1_RS05695	COG3620	sequence-specific DNA binding
AMAD1_RS05700	COG3550	peptidyl-serine autophosphorylation
AMAD1_RS05735	COG0668	transmembrane transport
AMAD1_RS05745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMAD1_RS05765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMAD1_RS05880	COG0789	Transcriptional regulator
AMAD1_RS05895	COG0789	Transcriptional regulator
AMAD1_RS05900	COG0640	Transcriptional regulator
AMAD1_RS05910	COG1230	cation diffusion facilitator family transporter
AMAD1_RS05950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMAD1_RS05965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMAD1_RS05980	COG0681	Belongs to the peptidase S26 family
AMAD1_RS06000	COG1074	ATP-dependent DNA helicase activity
AMAD1_RS06010	COG1404	Belongs to the peptidase S8 family
AMAD1_RS06015	COG0464	growth
AMAD1_RS06035	COG0629	single-stranded DNA binding
AMAD1_RS06050	COG0714	Associated with various cellular activities
AMAD1_RS06075	COG2003	Belongs to the UPF0758 family
AMAD1_RS06095	COG0583	DNA-binding transcription factor activity
AMAD1_RS06185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMAD1_RS06235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMAD1_RS06240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMAD1_RS06245	COG0564	pseudouridine synthase activity
AMAD1_RS06255	COG0612	Peptidase, M16
AMAD1_RS06260	COG2918	glutathione biosynthetic process
AMAD1_RS06280	COG2840	Smr protein MutS2
AMAD1_RS06285	COG2890	protein-(glutamine-N5) methyltransferase activity
AMAD1_RS06300	COG2719	SpoVR family
AMAD1_RS06305	COG2718	Belongs to the UPF0229 family
AMAD1_RS06310	COG2766	serine protein kinase
AMAD1_RS06315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMAD1_RS06320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMAD1_RS06325	COG4771	TonB-dependent receptor
AMAD1_RS06350	COG0450	alkyl hydroperoxide reductase
AMAD1_RS06355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMAD1_RS06360	COG2885	chlorophyll binding
AMAD1_RS06365	COG0584	glycerophosphoryl diester phosphodiesterase
AMAD1_RS06370	COG0346	lactoylglutathione lyase activity
AMAD1_RS06375	COG1278	Cold shock
AMAD1_RS06390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMAD1_RS06395	COG4660	Part of a membrane complex involved in electron transport
AMAD1_RS06400	COG4659	FMN binding
AMAD1_RS06405	COG4658	electron transport chain
AMAD1_RS06415	COG2878	Part of a membrane complex involved in electron transport
AMAD1_RS06420	COG4657	Part of a membrane complex involved in electron transport
AMAD1_RS06435	COG0534	Mate efflux family protein
AMAD1_RS06440	COG0556	nucleotide-excision repair
AMAD1_RS06455	COG0602	queuosine metabolic process
AMAD1_RS06465	COG0367	asparagine synthase
AMAD1_RS06490	COG3273	potassium ion transport
AMAD1_RS06490	COG0471	metal ion transport
AMAD1_RS06505	COG0529	Catalyzes the synthesis of activated sulfate
AMAD1_RS06510	COG0175	sulfate reduction
AMAD1_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMAD1_RS06520	COG3706	GGDEF domain
AMAD1_RS06545	COG2304	oxidoreductase activity
AMAD1_RS06565	COG0714	Associated with various cellular activities
AMAD1_RS06575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMAD1_RS06575	COG1024	Enoyl-CoA hydratase
AMAD1_RS06590	COG1025	Belongs to the peptidase M16 family
AMAD1_RS06595	COG2062	phosphohistidine phosphatase, SixA
AMAD1_RS06605	COG4536	flavin adenine dinucleotide binding
AMAD1_RS06610	COG4137	Cytochrome C assembly protein
AMAD1_RS06615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMAD1_RS06660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS06665	COG1132	(ABC) transporter
AMAD1_RS06680	COG0228	four-way junction DNA binding
AMAD1_RS06685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMAD1_RS06690	COG0336	Belongs to the RNA methyltransferase TrmD family
AMAD1_RS06695	COG0335	large ribosomal subunit rRNA binding
AMAD1_RS06700	COG2860	membrane
AMAD1_RS06710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMAD1_RS06715	COG0287	Prephenate dehydrogenase
AMAD1_RS06715	COG1605	Chorismate mutase
AMAD1_RS06720	COG0077	Prephenate dehydratase
AMAD1_RS06720	COG1605	Chorismate mutase
AMAD1_RS06725	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS06730	COG0023	Translation Initiation Factor
AMAD1_RS06760	COG2205	protein histidine kinase activity
AMAD1_RS06770	COG2204	response regulator
AMAD1_RS06790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMAD1_RS06795	COG0494	nUDIX hydrolase
AMAD1_RS06800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMAD1_RS06805	COG0632	four-way junction helicase activity
AMAD1_RS06810	COG2255	four-way junction helicase activity
AMAD1_RS06815	COG0824	Thioesterase
AMAD1_RS06820	COG0811	peptide transport
AMAD1_RS06835	COG0823	Involved in the tonB-independent uptake of proteins
AMAD1_RS06840	COG2885	chlorophyll binding
AMAD1_RS06845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AMAD1_RS06850	COG3344	reverse transcriptase
AMAD1_RS06870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMAD1_RS06890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMAD1_RS06905	COG4667	esterase of the alpha-beta hydrolase superfamily
AMAD1_RS06910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMAD1_RS06920	COG0784	Response regulator, receiver
AMAD1_RS06920	COG2205	protein histidine kinase activity
AMAD1_RS06940	COG3038	cytochrome b561
AMAD1_RS06960	COG0583	DNA-binding transcription factor activity
AMAD1_RS06965	COG1451	nucleotide metabolic process
AMAD1_RS06975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMAD1_RS06985	COG1309	transcriptional regulator
AMAD1_RS06990	COG4774	siderophore transport
AMAD1_RS07010	COG3706	GGDEF domain
AMAD1_RS07020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMAD1_RS07020	COG3008	intermembrane lipid transfer
AMAD1_RS07025	COG2995	paraquat-inducible protein a
AMAD1_RS07040	COG0017	Asparaginyl-tRNA synthetase
AMAD1_RS07055	COG0189	ligase activity
AMAD1_RS07085	COG0156	8-amino-7-oxononanoate synthase activity
AMAD1_RS07090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMAD1_RS07100	COG3340	Belongs to the peptidase S51 family
AMAD1_RS07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMAD1_RS07110	COG4139	cobalamin transport
AMAD1_RS07115	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AMAD1_RS07120	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMAD1_RS07135	COG5265	(ABC) transporter
AMAD1_RS07140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMAD1_RS07150	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS07170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMAD1_RS07210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMAD1_RS07225	COG2755	lipolytic protein G-D-S-L family
AMAD1_RS07230	COG4181	ATPase activity
AMAD1_RS07235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AMAD1_RS07240	COG1090	epimerase
AMAD1_RS07245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMAD1_RS07250	COG0628	permease
AMAD1_RS07275	COG2350	Protein conserved in bacteria
AMAD1_RS07280	COG0159	tryptophan synthase activity
AMAD1_RS07290	COG0135	phosphoribosylanthranilate isomerase activity
AMAD1_RS07290	COG0134	indole-3-glycerol-phosphate synthase activity
AMAD1_RS07295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMAD1_RS07305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMAD1_RS07310	COG0613	PHP domain protein
AMAD1_RS07315	COG0009	L-threonylcarbamoyladenylate synthase
AMAD1_RS07325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMAD1_RS07335	COG0656	L-ascorbic acid biosynthetic process
AMAD1_RS07340	COG0110	maltose O-acetyltransferase activity
AMAD1_RS07350	COG2733	membrane
AMAD1_RS07370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS07375	COG0500	methyltransferase
AMAD1_RS07380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMAD1_RS07385	COG0497	DNA recombination
AMAD1_RS07390	COG0783	Belongs to the Dps family
AMAD1_RS07395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMAD1_RS07400	COG1454	alcohol dehydrogenase
AMAD1_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS07415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMAD1_RS07420	COG2610	gluconate transmembrane transporter activity
AMAD1_RS07425	COG4771	TonB-dependent receptor
AMAD1_RS07435	COG2205	protein histidine kinase activity
AMAD1_RS07435	COG0784	Response regulator, receiver
AMAD1_RS07435	COG2198	Histidine kinase
AMAD1_RS07440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMAD1_RS07450	COG0484	heat shock protein binding
AMAD1_RS07455	COG3909	cytochrome
AMAD1_RS07460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMAD1_RS07475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMAD1_RS07480	COG0505	Belongs to the CarA family
AMAD1_RS07485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMAD1_RS07490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMAD1_RS07515	COG0857	belongs to the CobB CobQ family
AMAD1_RS07515	COG0280	phosphate acetyltransferase
AMAD1_RS07530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMAD1_RS07535	COG4535	Mg2 and Co2 transporter CorC
AMAD1_RS07545	COG1702	phosphate starvation-inducible protein PhoH
AMAD1_RS07555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMAD1_RS07585	COG1607	acyl-coa hydrolase
AMAD1_RS07590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMAD1_RS07600	COG1115	amino acid carrier protein
AMAD1_RS07650	COG0012	GTP binding
AMAD1_RS07665	COG1064	alcohol dehydrogenase
AMAD1_RS07680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMAD1_RS07690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMAD1_RS07695	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AMAD1_RS07700	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMAD1_RS07710	COG2890	protein-(glutamine-N5) methyltransferase activity
AMAD1_RS07715	COG0784	Response regulator, receiver
AMAD1_RS07715	COG3437	response regulator, receiver
AMAD1_RS07725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMAD1_RS07735	COG0583	DNA-binding transcription factor activity
AMAD1_RS07745	COG2363	Small membrane protein
AMAD1_RS07760	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AMAD1_RS07765	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AMAD1_RS07770	COG0515	serine threonine protein kinase
AMAD1_RS07775	COG2116	formate transmembrane transporter activity
AMAD1_RS07790	COG0714	Associated with various cellular activities
AMAD1_RS07795	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AMAD1_RS07800	COG0033	Phosphoglucomutase
AMAD1_RS07805	COG0058	SHG alpha-glucan phosphorylase activity
AMAD1_RS07815	COG2988	succinylglutamate desuccinylase activity
AMAD1_RS07850	COG1393	Belongs to the ArsC family
AMAD1_RS07875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMAD1_RS07905	COG5001	Diguanylate cyclase
AMAD1_RS07905	COG3300	MHYT domain
AMAD1_RS07930	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMAD1_RS07950	COG1733	regulation of RNA biosynthetic process
AMAD1_RS07955	COG5002	protein histidine kinase activity
AMAD1_RS07955	COG5001	Diguanylate cyclase
AMAD1_RS07955	COG3447	MASE1 domain protein
AMAD1_RS07965	COG0402	S-adenosylhomocysteine deaminase activity
AMAD1_RS07970	COG2351	hydroxyisourate hydrolase activity
AMAD1_RS07985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMAD1_RS08000	COG1309	transcriptional regulator
AMAD1_RS08015	COG2252	PERMEase
AMAD1_RS08020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMAD1_RS08035	COG4251	negative regulation of phosphorylation
AMAD1_RS08035	COG3706	GGDEF domain
AMAD1_RS08035	COG5001	Diguanylate cyclase
AMAD1_RS08035	COG2203	Gaf domain
AMAD1_RS08040	COG4251	negative regulation of phosphorylation
AMAD1_RS08040	COG5001	Diguanylate cyclase
AMAD1_RS08040	COG3706	GGDEF domain
AMAD1_RS08040	COG2203	Gaf domain
AMAD1_RS08045	COG0784	Response regulator, receiver
AMAD1_RS08045	COG2205	protein histidine kinase activity
AMAD1_RS08060	COG2233	PERMEase
AMAD1_RS08075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMAD1_RS08080	COG0730	response to heat
AMAD1_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS08125	COG3001	Fructosamine kinase
AMAD1_RS08135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMAD1_RS08150	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AMAD1_RS08150	COG0662	Cupin 2, conserved barrel domain protein
AMAD1_RS08155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMAD1_RS08165	COG1596	polysaccharide export
AMAD1_RS08170	COG0489	protein tyrosine kinase activity
AMAD1_RS08175	COG4464	protein tyrosine phosphatase activity
AMAD1_RS08245	COG1215	transferase activity, transferring glycosyl groups
AMAD1_RS08250	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS08260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMAD1_RS08280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMAD1_RS08280	COG0072	phenylalanine-tRNA ligase activity
AMAD1_RS08295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMAD1_RS08305	COG1472	Belongs to the glycosyl hydrolase 3 family
AMAD1_RS08310	COG2096	Adenosyltransferase
AMAD1_RS08320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMAD1_RS08330	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMAD1_RS08355	COG0708	Exodeoxyribonuclease III
AMAD1_RS08390	COG2814	Major facilitator Superfamily
AMAD1_RS08425	COG4770	biotin carboxylase activity
AMAD1_RS08430	COG1024	Enoyl-CoA hydratase
AMAD1_RS08435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMAD1_RS08440	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS08445	COG0789	Transcriptional regulator
AMAD1_RS08450	COG0183	Belongs to the thiolase family
AMAD1_RS08465	COG3706	GGDEF domain
AMAD1_RS08475	COG2925	Exonuclease
AMAD1_RS08480	COG0582	viral genome integration into host DNA
AMAD1_RS08520	COG1674	ftsk spoiiie
AMAD1_RS08520	COG0531	amino acid
AMAD1_RS08560	COG2197	response regulator
AMAD1_RS08575	COG3617	BRO family, N-terminal domain
AMAD1_RS08645	COG0305	Participates in initiation and elongation during chromosome replication
AMAD1_RS08735	COG3728	DNA packaging
AMAD1_RS08735	COG5484	DNA packaging
AMAD1_RS08880	COG1643	Atp-dependent helicase
AMAD1_RS08900	COG3321	synthase
AMAD1_RS08900	COG0604	alcohol dehydrogenase
AMAD1_RS08905	COG0328	RNA-DNA hybrid ribonuclease activity
AMAD1_RS08910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMAD1_RS08940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMAD1_RS08945	COG1136	(ABC) transporter
AMAD1_RS08950	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMAD1_RS08965	COG3724	N-succinylarginine dihydrolase activity
AMAD1_RS08990	COG0746	molybdenum cofactor guanylyltransferase activity
AMAD1_RS08995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMAD1_RS09000	COG0243	molybdopterin cofactor binding
AMAD1_RS09005	COG2153	protein acetylation
AMAD1_RS09020	COG1530	ribonuclease E activity
AMAD1_RS09035	COG0424	maF-like protein
AMAD1_RS09040	COG1399	metal-binding, possibly nucleic acid-binding protein
AMAD1_RS09050	COG0416	fatty acid biosynthetic process
AMAD1_RS09055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMAD1_RS09060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMAD1_RS09070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMAD1_RS09075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMAD1_RS09085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMAD1_RS09100	COG0084	hydrolase, TatD family'
AMAD1_RS09110	COG0702	epimerase
AMAD1_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS09140	COG0596	Alpha beta hydrolase
AMAD1_RS09150	COG0183	Belongs to the thiolase family
AMAD1_RS09155	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS09175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMAD1_RS09185	COG0246	Mannitol dehydrogenase
AMAD1_RS09205	COG0668	transmembrane transport
AMAD1_RS09210	COG4771	TonB-dependent receptor
AMAD1_RS09235	COG3437	response regulator, receiver
AMAD1_RS09245	COG0195	Participates in both transcription termination and antitermination
AMAD1_RS09260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMAD1_RS09275	COG1187	pseudouridine synthase activity
AMAD1_RS09285	COG3153	acetyltransferase
AMAD1_RS09285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMAD1_RS09360	COG1032	radical SAM domain protein
AMAD1_RS09375	COG4771	TonB-dependent receptor
AMAD1_RS09380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMAD1_RS09390	COG4134	Bacterial extracellular solute-binding protein
AMAD1_RS09400	COG4136	ATPase activity
AMAD1_RS09405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMAD1_RS09430	COG2203	Gaf domain
AMAD1_RS09430	COG4251	negative regulation of phosphorylation
AMAD1_RS09430	COG3706	GGDEF domain
AMAD1_RS09430	COG5001	Diguanylate cyclase
AMAD1_RS09460	COG2801	Transposase and inactivated derivatives
AMAD1_RS09465	COG4372	Transposase
AMAD1_RS09475	COG1902	pentaerythritol trinitrate reductase activity
AMAD1_RS09485	COG2867	negative regulation of translational initiation
AMAD1_RS09490	COG2914	Belongs to the UPF0125 (RnfH) family
AMAD1_RS09500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMAD1_RS09505	COG4771	TonB-dependent receptor
AMAD1_RS09510	COG0457	Tetratricopeptide repeat
AMAD1_RS09525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMAD1_RS09525	COG0574	Belongs to the PEP-utilizing enzyme family
AMAD1_RS09560	COG2850	peptidyl-arginine hydroxylation
AMAD1_RS09570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMAD1_RS09575	COG2915	High frequency lysogenization protein hflD homolog
AMAD1_RS09580	COG0482	sulfurtransferase activity
AMAD1_RS09585	COG1187	pseudouridine synthase activity
AMAD1_RS09595	COG1278	Cold shock
AMAD1_RS09600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMAD1_RS09605	COG0542	response to heat
AMAD1_RS09610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMAD1_RS09615	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMAD1_RS09620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMAD1_RS09625	COG0492	ferredoxin-NADP+ reductase activity
AMAD1_RS09635	COG3091	SprT-like family
AMAD1_RS09640	COG0616	signal peptide processing
AMAD1_RS09655	COG0778	Nitroreductase
AMAD1_RS09665	COG0252	asparaginase activity
AMAD1_RS09670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMAD1_RS09675	COG0321	lipoyl(octanoyl) transferase activity
AMAD1_RS09680	COG2921	Belongs to the UPF0250 family
AMAD1_RS09685	COG1686	Belongs to the peptidase S11 family
AMAD1_RS09690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMAD1_RS09695	COG0772	Belongs to the SEDS family
AMAD1_RS09700	COG0768	penicillin binding
AMAD1_RS09705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMAD1_RS09710	COG0799	negative regulation of ribosome biogenesis
AMAD1_RS09720	COG1466	dna polymerase III delta subunit
AMAD1_RS09725	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AMAD1_RS09730	COG0495	leucyl-tRNA aminoacylation
AMAD1_RS09745	COG1067	ATP-dependent peptidase activity
AMAD1_RS09750	COG0596	Alpha beta hydrolase
AMAD1_RS09765	COG1534	Rna-binding protein
AMAD1_RS09770	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMAD1_RS09775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMAD1_RS09780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMAD1_RS09785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMAD1_RS09790	COG0149	triose-phosphate isomerase activity
AMAD1_RS09795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMAD1_RS09805	COG3300	MHYT domain
AMAD1_RS09805	COG5001	Diguanylate cyclase
AMAD1_RS09825	COG1803	Methylglyoxal synthase
AMAD1_RS09825	COG1597	lipid kinase activity
AMAD1_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS09840	COG0561	phosphatase activity
AMAD1_RS09855	COG2801	Transposase and inactivated derivatives
AMAD1_RS09865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMAD1_RS09870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMAD1_RS09875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMAD1_RS09890	COG1185	polyribonucleotide nucleotidyltransferase activity
AMAD1_RS09915	COG1819	glycosyl
AMAD1_RS09955	COG3547	Transposase (IS116 IS110 IS902 family)
AMAD1_RS10005	COG2801	Transposase and inactivated derivatives
AMAD1_RS10080	COG4372	Transposase
AMAD1_RS10110	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AMAD1_RS10115	COG1196	nuclear chromosome segregation
AMAD1_RS10125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMAD1_RS10140	COG1132	(ABC) transporter
AMAD1_RS10145	COG1663	tetraacyldisaccharide 4'-kinase activity
AMAD1_RS10180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMAD1_RS10185	COG0435	Glutathione S-transferase
AMAD1_RS10190	COG1741	Belongs to the pirin family
AMAD1_RS10195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMAD1_RS10205	COG0372	Belongs to the citrate synthase family
AMAD1_RS10215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMAD1_RS10220	COG1053	succinate dehydrogenase
AMAD1_RS10225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMAD1_RS10230	COG0567	Dehydrogenase, E1 component
AMAD1_RS10235	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMAD1_RS10270	COG4667	esterase of the alpha-beta hydrolase superfamily
AMAD1_RS10290	COG0366	Alpha amylase catalytic
AMAD1_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS10320	COG2267	carboxylic ester hydrolase activity
AMAD1_RS10330	COG0616	signal peptide processing
AMAD1_RS10350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMAD1_RS10355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMAD1_RS10360	COG0386	Belongs to the glutathione peroxidase family
AMAD1_RS10365	COG2084	Dehydrogenase
AMAD1_RS10375	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS10380	COG1024	Enoyl-CoA hydratase
AMAD1_RS10385	COG2226	methyltransferase
AMAD1_RS10390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMAD1_RS10395	COG3083	sulfuric ester hydrolase activity
AMAD1_RS10400	COG3082	Protein of unknown function (DUF1414)
AMAD1_RS10405	COG3081	Nucleoid-associated protein
AMAD1_RS10435	COG3275	phosphorelay sensor kinase activity
AMAD1_RS10440	COG3279	Response regulator of the LytR AlgR family
AMAD1_RS10445	COG0205	6-phosphofructokinase activity
AMAD1_RS10460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMAD1_RS10475	COG2205	protein histidine kinase activity
AMAD1_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMAD1_RS10485	COG1054	Belongs to the UPF0176 family
AMAD1_RS10495	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS10505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMAD1_RS10510	COG0583	DNA-binding transcription factor activity
AMAD1_RS10530	COG1760	l-serine dehydratase
AMAD1_RS10555	COG1322	Protein conserved in bacteria
AMAD1_RS10560	COG1404	Belongs to the peptidase S8 family
AMAD1_RS10565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMAD1_RS10570	COG0022	dehydrogenase e1 component
AMAD1_RS10580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMAD1_RS10585	COG0515	serine threonine protein kinase
AMAD1_RS10590	COG1946	Acyl-CoA thioesterase
AMAD1_RS10600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMAD1_RS10610	COG1956	GAF domain-containing protein
AMAD1_RS10625	COG0793	Belongs to the peptidase S41A family
AMAD1_RS10630	COG0733	neurotransmitter:sodium symporter activity
AMAD1_RS10635	COG1757	Na H antiporter
AMAD1_RS10640	COG0308	aminopeptidase N
AMAD1_RS10670	COG2902	Dehydrogenase
AMAD1_RS10675	COG0167	dihydroorotate dehydrogenase activity
AMAD1_RS10690	COG0488	(ABC) transporter
AMAD1_RS10700	COG3130	regulation of translation
AMAD1_RS10705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMAD1_RS10715	COG0415	Belongs to the DNA photolyase family
AMAD1_RS10720	COG0415	Belongs to the DNA photolyase family
AMAD1_RS10725	COG0415	Belongs to the DNA photolyase family
AMAD1_RS10730	COG3046	protein related to deoxyribodipyrimidine photolyase
AMAD1_RS10740	COG4974	Belongs to the 'phage' integrase family
AMAD1_RS10750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMAD1_RS10755	COG0589	response to stress
AMAD1_RS10765	COG0069	glutamate synthase activity
AMAD1_RS10780	COG2193	ferroxidase activity
AMAD1_RS10790	COG3278	Belongs to the heme-copper respiratory oxidase family
AMAD1_RS10805	COG2010	Cytochrome c
AMAD1_RS10830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMAD1_RS10835	COG0589	response to stress
AMAD1_RS10840	COG0037	tRNA processing
AMAD1_RS10845	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMAD1_RS10865	COG1280	lysine exporter protein (LysE YggA)
AMAD1_RS10875	COG2897	thiosulfate sulfurtransferase activity
AMAD1_RS10880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AMAD1_RS10885	COG3148	PFAM DTW domain containing protein
AMAD1_RS10910	COG0322	excinuclease ABC activity
AMAD1_RS10915	COG2197	response regulator
AMAD1_RS10920	COG0436	Aminotransferase
AMAD1_RS10940	COG2259	Doxx family
AMAD1_RS10945	COG0583	DNA-binding transcription factor activity
AMAD1_RS10960	COG0670	Belongs to the BI1 family
AMAD1_RS10965	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AMAD1_RS10980	COG2920	part of a sulfur-relay system
AMAD1_RS11010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMAD1_RS11020	COG0531	amino acid
AMAD1_RS11020	COG1674	ftsk spoiiie
AMAD1_RS11030	COG0686	Belongs to the AlaDH PNT family
AMAD1_RS11035	COG0284	orotidine-5'-phosphate decarboxylase activity
AMAD1_RS11040	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AMAD1_RS11055	COG0776	regulation of translation
AMAD1_RS11060	COG0539	negative regulation of cytoplasmic translation
AMAD1_RS11065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMAD1_RS11075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMAD1_RS11085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMAD1_RS11090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMAD1_RS11095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMAD1_RS11100	COG0633	Ferredoxin
AMAD1_RS11130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AMAD1_RS11135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMAD1_RS11145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMAD1_RS11155	COG4783	chaperone-mediated protein folding
AMAD1_RS11165	COG1393	Belongs to the ArsC family
AMAD1_RS11180	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMAD1_RS11195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMAD1_RS11205	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS11230	COG0572	uridine kinase
AMAD1_RS11235	COG3769	mannosylglycerate metabolic process
AMAD1_RS11240	COG1215	transferase activity, transferring glycosyl groups
AMAD1_RS11245	COG0366	Alpha amylase catalytic
AMAD1_RS11255	COG0303	'Molybdopterin
AMAD1_RS11260	COG0534	Mate efflux family protein
AMAD1_RS11275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMAD1_RS11280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMAD1_RS11310	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AMAD1_RS11330	COG3547	Transposase (IS116 IS110 IS902 family)
AMAD1_RS11355	COG0405	Gamma-glutamyltransferase
AMAD1_RS11360	COG1024	Enoyl-CoA hydratase
AMAD1_RS11405	COG1448	Aminotransferase
AMAD1_RS11415	COG1671	Belongs to the UPF0178 family
AMAD1_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS11430	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS11435	COG0662	Cupin 2, conserved barrel domain protein
AMAD1_RS11435	COG2207	Transcriptional regulator
AMAD1_RS11450	COG3344	reverse transcriptase
AMAD1_RS11460	COG1505	serine-type exopeptidase activity
AMAD1_RS11470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS11500	COG0596	Alpha beta hydrolase
AMAD1_RS11510	COG0716	FMN binding
AMAD1_RS11520	COG0735	belongs to the Fur family
AMAD1_RS11530	COG1984	allophanate hydrolase subunit 2
AMAD1_RS11535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMAD1_RS11540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AMAD1_RS11545	COG2996	Protein conserved in bacteria
AMAD1_RS11550	COG1765	OsmC-like protein
AMAD1_RS11555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS11565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMAD1_RS11580	COG0436	Aminotransferase
AMAD1_RS11585	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMAD1_RS11590	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMAD1_RS11600	COG2010	Cytochrome c
AMAD1_RS11600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMAD1_RS11605	COG2080	2 iron, 2 sulfur cluster binding
AMAD1_RS11630	COG1073	alpha beta
AMAD1_RS11635	COG2207	Transcriptional regulator
AMAD1_RS11645	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMAD1_RS11650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMAD1_RS11675	COG3012	SEC-C Motif Domain Protein
AMAD1_RS11680	COG0604	alcohol dehydrogenase
AMAD1_RS11690	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS11700	COG4771	TonB-dependent receptor
AMAD1_RS11725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMAD1_RS11745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMAD1_RS11750	COG0315	cyclic pyranopterin monophosphate synthase activity
AMAD1_RS11755	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMAD1_RS11770	COG2161	toxin-antitoxin pair type II binding
AMAD1_RS11775	COG4115	mRNA cleavage
AMAD1_RS11790	COG0436	Aminotransferase
AMAD1_RS11795	COG3268	Saccharopine dehydrogenase
AMAD1_RS11800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMAD1_RS11815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMAD1_RS11820	COG4206	TonB-dependent receptor
AMAD1_RS11830	COG5006	permease, DMT superfamily
AMAD1_RS11845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMAD1_RS11850	COG1074	ATP-dependent DNA helicase activity
AMAD1_RS11855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AMAD1_RS11870	COG1022	Amp-dependent synthetase and ligase
AMAD1_RS11875	COG3706	GGDEF domain
AMAD1_RS11875	COG5001	Diguanylate cyclase
AMAD1_RS11875	COG4251	negative regulation of phosphorylation
AMAD1_RS11875	COG2203	Gaf domain
AMAD1_RS11895	COG0583	DNA-binding transcription factor activity
AMAD1_RS11910	COG0640	Transcriptional regulator
AMAD1_RS11930	COG2204	response regulator
AMAD1_RS11940	COG4251	negative regulation of phosphorylation
AMAD1_RS11945	COG0784	Response regulator, receiver
AMAD1_RS11950	COG2205	protein histidine kinase activity
AMAD1_RS11950	COG0784	Response regulator, receiver
AMAD1_RS11975	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMAD1_RS12000	COG3139	Protein of unknown function (DUF1315)
AMAD1_RS12015	COG1115	amino acid carrier protein
AMAD1_RS12020	COG2866	Carboxypeptidase
AMAD1_RS12040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMAD1_RS12050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMAD1_RS12055	COG1640	4-alpha-glucanotransferase
AMAD1_RS12060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMAD1_RS12065	COG0676	glucose-6-phosphate 1-epimerase activity
AMAD1_RS12070	COG0800	Aldolase
AMAD1_RS12080	COG0129	dihydroxy-acid dehydratase activity
AMAD1_RS12090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMAD1_RS12095	COG1737	Transcriptional regulator
AMAD1_RS12100	COG0469	pyruvate kinase activity
AMAD1_RS12115	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS12135	COG0471	metal ion transport
AMAD1_RS12135	COG0490	domain, Protein
AMAD1_RS12145	COG0800	Aldolase
AMAD1_RS12155	COG0129	dihydroxy-acid dehydratase activity
AMAD1_RS12165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMAD1_RS12170	COG1737	Transcriptional regulator
AMAD1_RS12175	COG0469	pyruvate kinase activity
AMAD1_RS12180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMAD1_RS12200	COG2823	Periplasmic or secreted lipoprotein
AMAD1_RS12230	COG3665	Urea carboxylase-associated protein
AMAD1_RS12260	COG2356	endonuclease I
AMAD1_RS12280	COG0583	DNA-binding transcription factor activity
AMAD1_RS12285	COG1979	alcohol dehydrogenase
AMAD1_RS12300	COG0784	Response regulator, receiver
AMAD1_RS12300	COG3437	response regulator, receiver
AMAD1_RS12400	COG0471	metal ion transport
AMAD1_RS12410	COG0489	protein tyrosine kinase activity
AMAD1_RS12415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMAD1_RS12415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMAD1_RS12420	COG0668	transmembrane transport
AMAD1_RS12425	COG2226	methyltransferase
AMAD1_RS12430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMAD1_RS12435	COG1388	LysM domain
AMAD1_RS12435	COG0741	lytic transglycosylase activity
AMAD1_RS12460	COG0215	cysteine-tRNA ligase activity
AMAD1_RS12465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMAD1_RS12470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMAD1_RS12480	COG2268	Band 7 protein
AMAD1_RS12495	COG1733	regulation of RNA biosynthetic process
AMAD1_RS12500	COG0604	alcohol dehydrogenase
AMAD1_RS12505	COG0753	catalase activity
AMAD1_RS12510	COG0604	alcohol dehydrogenase
AMAD1_RS12515	COG0583	DNA-binding transcription factor activity
AMAD1_RS12550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMAD1_RS12555	COG1286	toxin biosynthetic process
AMAD1_RS12560	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AMAD1_RS12565	COG0285	dihydrofolate synthase activity
AMAD1_RS12585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMAD1_RS12590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMAD1_RS12610	COG3609	addiction module antidote protein, CC2985 family
AMAD1_RS12620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMAD1_RS12625	COG0318	PFAM AMP-dependent synthetase and ligase
AMAD1_RS12635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMAD1_RS12635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMAD1_RS12670	COG0789	Transcriptional regulator
AMAD1_RS12675	COG0604	alcohol dehydrogenase
AMAD1_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS12705	COG1119	ATPase activity
AMAD1_RS12710	COG2031	fatty acid transporter
AMAD1_RS12715	COG5002	protein histidine kinase activity
AMAD1_RS12715	COG2205	protein histidine kinase activity
AMAD1_RS12715	COG0784	Response regulator, receiver
AMAD1_RS12725	COG0612	Peptidase, M16
AMAD1_RS12740	COG3101	peptidyl-lysine hydroxylation
AMAD1_RS12770	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMAD1_RS12770	COG1902	pentaerythritol trinitrate reductase activity
AMAD1_RS12795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMAD1_RS12805	COG4399	Belongs to the UPF0754 family
AMAD1_RS12830	COG1770	oligopeptidase
AMAD1_RS12835	COG2186	Transcriptional regulator
AMAD1_RS12845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMAD1_RS12850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMAD1_RS12860	COG2983	Belongs to the UPF0260 family
AMAD1_RS12865	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMAD1_RS12885	COG0318	PFAM AMP-dependent synthetase and ligase
AMAD1_RS12890	COG2267	carboxylic ester hydrolase activity
AMAD1_RS12905	COG1214	PFAM Peptidase M22, glycoprotease
AMAD1_RS12910	COG1199	ATP-dependent helicase activity
AMAD1_RS12960	COG4771	TonB-dependent receptor
AMAD1_RS12970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMAD1_RS12975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMAD1_RS12980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMAD1_RS12985	COG0131	Imidazoleglycerol-phosphate dehydratase
AMAD1_RS12985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMAD1_RS12990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMAD1_RS13020	COG2116	formate transmembrane transporter activity
AMAD1_RS13025	COG0612	Peptidase, M16
AMAD1_RS13055	COG0326	Molecular chaperone. Has ATPase activity
AMAD1_RS13060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMAD1_RS13085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMAD1_RS13095	COG3220	belongs to the UPF0276 family
AMAD1_RS13105	COG1136	(ABC) transporter
AMAD1_RS13105	COG0577	efflux transmembrane transporter activity
AMAD1_RS13115	COG2203	Gaf domain
AMAD1_RS13115	COG3706	GGDEF domain
AMAD1_RS13115	COG5001	Diguanylate cyclase
AMAD1_RS13115	COG4251	negative regulation of phosphorylation
AMAD1_RS13145	COG1183	phosphatidylcholine synthase activity
AMAD1_RS13165	COG0277	FAD linked oxidase domain protein
AMAD1_RS13170	COG0542	response to heat
AMAD1_RS13195	COG1595	DNA-templated transcription, initiation
AMAD1_RS13210	COG4221	oxidoreductase activity
AMAD1_RS13225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMAD1_RS13235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMAD1_RS13245	COG0142	geranyltranstransferase activity
AMAD1_RS13255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AMAD1_RS13260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMAD1_RS13270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMAD1_RS13285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMAD1_RS13285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMAD1_RS13300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMAD1_RS13305	COG0488	(ABC) transporter
AMAD1_RS13315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMAD1_RS13325	COG0560	Phosphoserine phosphatase
AMAD1_RS13335	COG0084	hydrolase, TatD family'
AMAD1_RS13350	COG0571	ribonuclease III activity
AMAD1_RS13380	COG1595	DNA-templated transcription, initiation
AMAD1_RS13385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMAD1_RS13400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AMAD1_RS13480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMAD1_RS13485	COG1047	Peptidyl-prolyl cis-trans
AMAD1_RS13495	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMAD1_RS13500	COG0196	riboflavin kinase activity
AMAD1_RS13505	COG0728	peptidoglycan biosynthetic process
AMAD1_RS13510	COG0268	Binds directly to 16S ribosomal RNA
AMAD1_RS13530	COG0385	Bile acid
AMAD1_RS13560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMAD1_RS13565	COG0776	regulation of translation
AMAD1_RS13575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMAD1_RS13580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMAD1_RS13585	COG0740	serine-type endopeptidase activity
AMAD1_RS13590	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMAD1_RS13645	COG1720	tRNA m6t6A37 methyltransferase activity
AMAD1_RS13655	COG1234	tRNA 3'-trailer cleavage
AMAD1_RS13665	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMAD1_RS13680	COG0517	IMP dehydrogenase activity
AMAD1_RS13680	COG0516	GMP reductase activity
AMAD1_RS13685	COG1570	exodeoxyribonuclease VII activity
AMAD1_RS13705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMAD1_RS13710	COG2976	Protein conserved in bacteria
AMAD1_RS13735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMAD1_RS13745	COG2166	iron-sulfur cluster assembly
AMAD1_RS13760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMAD1_RS13765	COG0719	Fe-S assembly protein
AMAD1_RS13770	COG0396	ATPase activity
AMAD1_RS13775	COG0719	Fe-S assembly protein
AMAD1_RS13780	COG1104	cysteine desulfurase activity
AMAD1_RS13790	COG2072	flavoprotein involved in K transport
AMAD1_RS13795	COG1045	serine acetyltransferase
AMAD1_RS13800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMAD1_RS13805	COG0483	inositol monophosphate 1-phosphatase activity
AMAD1_RS13820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMAD1_RS13825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMAD1_RS13830	COG1862	Preprotein translocase
AMAD1_RS13835	COG0343	queuine tRNA-ribosyltransferase activity
AMAD1_RS13855	COG1842	Phage shock protein A
AMAD1_RS13860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMAD1_RS13880	COG0754	glutathionylspermidine amidase activity
AMAD1_RS13910	COG2066	Belongs to the glutaminase family
AMAD1_RS13915	COG1785	Belongs to the alkaline phosphatase family
AMAD1_RS13920	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS13990	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS14010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMAD1_RS14015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMAD1_RS14050	COG2755	lipolytic protein G-D-S-L family
AMAD1_RS14050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMAD1_RS14055	COG0367	asparagine synthase
AMAD1_RS14060	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS14070	COG2244	polysaccharide biosynthetic process
AMAD1_RS14100	COG0367	asparagine synthase
AMAD1_RS14135	COG0489	protein tyrosine kinase activity
AMAD1_RS14145	COG3267	Type II secretory pathway component ExeA
AMAD1_RS14145	COG3409	Peptidoglycan-binding domain 1 protein
AMAD1_RS14195	COG1560	Kdo2-lipid A biosynthetic process
AMAD1_RS14210	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS14225	COG3300	MHYT domain
AMAD1_RS14225	COG5001	Diguanylate cyclase
AMAD1_RS14230	COG1435	thymidine kinase activity
AMAD1_RS14240	COG1609	Transcriptional regulator
AMAD1_RS14245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMAD1_RS14270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMAD1_RS14275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMAD1_RS14280	COG1024	Enoyl-CoA hydratase
AMAD1_RS14280	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMAD1_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
AMAD1_RS14315	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AMAD1_RS14340	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS14370	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS14375	COG2205	protein histidine kinase activity
AMAD1_RS14415	COG2080	2 iron, 2 sulfur cluster binding
AMAD1_RS14420	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMAD1_RS14425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMAD1_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
AMAD1_RS14450	COG4221	oxidoreductase activity
AMAD1_RS14455	COG0693	protein deglycase activity
AMAD1_RS14460	COG1295	ribonuclease BN
AMAD1_RS14500	COG2814	Major facilitator Superfamily
AMAD1_RS14515	COG0514	ATP-dependent DNA helicase (RecQ)
AMAD1_RS14545	COG4251	negative regulation of phosphorylation
AMAD1_RS14550	COG2133	pyrroloquinoline quinone binding
AMAD1_RS14555	COG3609	addiction module antidote protein, CC2985 family
AMAD1_RS14585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMAD1_RS14590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMAD1_RS14605	COG0330	HflC and HflK could
AMAD1_RS14695	COG4772	TonB-dependent receptor
AMAD1_RS14740	COG4372	Transposase
AMAD1_RS14755	COG1017	nitric oxide dioxygenase activity
AMAD1_RS14755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMAD1_RS14760	COG3604	Transcriptional regulator
AMAD1_RS14775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMAD1_RS14775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMAD1_RS14790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMAD1_RS14795	COG2971	BadF BadG BcrA BcrD
AMAD1_RS14800	COG0583	DNA-binding transcription factor activity
AMAD1_RS14805	COG1620	l-lactate permease
AMAD1_RS14825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMAD1_RS14830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMAD1_RS14835	COG0006	proline dipeptidase activity
AMAD1_RS14845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMAD1_RS14860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMAD1_RS14865	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMAD1_RS14870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMAD1_RS14890	COG3313	Fe-S protein
AMAD1_RS14925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMAD1_RS14930	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMAD1_RS14935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMAD1_RS14950	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMAD1_RS14955	COG3577	Aspartyl protease
AMAD1_RS14960	COG0157	Belongs to the NadC ModD family
AMAD1_RS14970	COG1459	type II secretion system
AMAD1_RS14975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMAD1_RS14980	COG0237	dephospho-CoA kinase activity
AMAD1_RS14985	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AMAD1_RS14990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMAD1_RS14995	COG3608	succinylglutamate desuccinylase aspartoacylase
AMAD1_RS15000	COG0494	nUDIX hydrolase
AMAD1_RS15010	COG0739	heme binding
AMAD1_RS15015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMAD1_RS15020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMAD1_RS15025	COG0849	cell division
AMAD1_RS15030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMAD1_RS15035	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMAD1_RS15040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMAD1_RS15050	COG0772	Belongs to the SEDS family
AMAD1_RS15055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMAD1_RS15065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMAD1_RS15070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMAD1_RS15075	COG0768	penicillin binding
AMAD1_RS15080	COG3116	cell division
AMAD1_RS15090	COG2001	Belongs to the MraZ family
AMAD1_RS15130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMAD1_RS15130	COG0678	peroxiredoxin activity
AMAD1_RS15155	COG2204	response regulator
AMAD1_RS15160	COG2205	protein histidine kinase activity
AMAD1_RS15160	COG0784	Response regulator, receiver
AMAD1_RS15185	COG0668	transmembrane transport
AMAD1_RS15190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMAD1_RS15195	COG0189	ligase activity
AMAD1_RS15200	COG1678	Uncharacterized ACR, COG1678
AMAD1_RS15205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMAD1_RS15230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMAD1_RS15235	COG0762	integral membrane protein
AMAD1_RS15245	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMAD1_RS15245	COG1902	pentaerythritol trinitrate reductase activity
AMAD1_RS15260	COG0625	glutathione transferase activity
AMAD1_RS15270	COG1764	response to oxidative stress
AMAD1_RS15275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMAD1_RS15290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMAD1_RS15300	COG2814	Major facilitator Superfamily
AMAD1_RS15305	COG0724	RNA recognition motif
AMAD1_RS15330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMAD1_RS15335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMAD1_RS15340	COG0083	homoserine kinase activity
AMAD1_RS15355	COG0583	DNA-binding transcription factor activity
AMAD1_RS15370	COG0640	Transcriptional regulator
AMAD1_RS15380	COG0431	NADPH-dependent FMN reductase
AMAD1_RS15385	COG0798	PFAM Bile acid sodium symporter
AMAD1_RS15390	COG2201	protein-glutamate methylesterase activity
AMAD1_RS15395	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMAD1_RS15405	COG0642	Histidine kinase
AMAD1_RS15430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMAD1_RS15455	COG1748	Saccharopine dehydrogenase
AMAD1_RS15470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMAD1_RS15475	COG3107	peptidoglycan biosynthetic process
AMAD1_RS15485	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS15495	COG2823	Periplasmic or secreted lipoprotein
AMAD1_RS15515	COG4585	Histidine kinase
AMAD1_RS15520	COG2197	response regulator
AMAD1_RS15535	COG4771	TonB-dependent receptor
AMAD1_RS15545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMAD1_RS15550	COG0372	Belongs to the citrate synthase family
AMAD1_RS15555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMAD1_RS15560	COG2828	Protein conserved in bacteria
AMAD1_RS15565	COG2199	diguanylate cyclase activity
AMAD1_RS15565	COG2203	Gaf domain
AMAD1_RS15570	COG1940	carbohydrate kinase activity
AMAD1_RS15610	COG5002	protein histidine kinase activity
AMAD1_RS15610	COG2198	Histidine kinase
AMAD1_RS15610	COG0784	Response regulator, receiver
AMAD1_RS15615	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMAD1_RS15620	COG0069	glutamate synthase activity
AMAD1_RS15620	COG0070	glutamate synthase
AMAD1_RS15620	COG0067	glutamate synthase
AMAD1_RS15625	COG0493	'glutamate synthase
AMAD1_RS15640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMAD1_RS15645	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMAD1_RS15650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMAD1_RS15655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMAD1_RS15670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMAD1_RS15675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMAD1_RS15685	COG4942	peptidase
AMAD1_RS15690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMAD1_RS15695	COG0738	Major facilitator superfamily
AMAD1_RS15705	COG1902	pentaerythritol trinitrate reductase activity
AMAD1_RS15725	COG0625	glutathione transferase activity
AMAD1_RS15750	COG2894	cell division
AMAD1_RS15755	COG0850	regulation of cytokinetic process
AMAD1_RS15765	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AMAD1_RS15780	COG1981	membrane
AMAD1_RS15795	COG1914	H( )-stimulated, divalent metal cation uptake system
AMAD1_RS15810	COG1217	gtp-binding protein TYPA
AMAD1_RS15815	COG0174	glutamine synthetase
AMAD1_RS15825	COG3852	Histidine kinase
AMAD1_RS15830	COG2204	response regulator
AMAD1_RS15835	COG3437	response regulator, receiver
AMAD1_RS15875	COG3850	Histidine kinase
AMAD1_RS15875	COG4999	Histidine kinase
AMAD1_RS15875	COG2205	protein histidine kinase activity
AMAD1_RS15875	COG3437	response regulator, receiver
AMAD1_RS15880	COG0525	valine-tRNA ligase activity
AMAD1_RS15885	COG2927	DNA polymerase III (CHI subunit)
AMAD1_RS15890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMAD1_RS15895	COG0795	lipopolysaccharide-transporting ATPase activity
AMAD1_RS15900	COG0795	lipopolysaccharide-transporting ATPase activity
AMAD1_RS15995	COG4974	Belongs to the 'phage' integrase family
AMAD1_RS16010	COG2856	Zn peptidase
AMAD1_RS16120	COG3250	beta-galactosidase activity
AMAD1_RS16130	COG4948	Mandelate Racemase Muconate Lactonizing
AMAD1_RS16135	COG3661	Belongs to the glycosyl hydrolase 67 family
AMAD1_RS16150	COG2199	diguanylate cyclase activity
AMAD1_RS16150	COG2203	Gaf domain
AMAD1_RS16180	COG0673	inositol 2-dehydrogenase activity
AMAD1_RS16190	COG0628	permease
AMAD1_RS16205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMAD1_RS16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMAD1_RS16215	COG4558	Periplasmic binding protein
AMAD1_RS16225	COG4206	TonB-dependent receptor
AMAD1_RS16235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMAD1_RS16265	COG1971	Probably functions as a manganese efflux pump
AMAD1_RS16275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMAD1_RS16290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMAD1_RS16300	COG0679	Auxin Efflux Carrier
AMAD1_RS16330	COG1131	(ABC) transporter
AMAD1_RS16350	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AMAD1_RS16390	COG2205	protein histidine kinase activity
AMAD1_RS16400	COG3901	Regulator of nitric oxide reductase transcription
AMAD1_RS16400	COG0348	domain, Protein
AMAD1_RS16410	COG2197	response regulator
AMAD1_RS16435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMAD1_RS16450	COG4771	TonB-dependent receptor
AMAD1_RS16460	COG0583	DNA-binding transcription factor activity
AMAD1_RS16465	COG1304	FMN binding
AMAD1_RS16470	COG0277	FAD linked oxidase domain protein
AMAD1_RS16480	COG1462	curli production assembly transport component CsgG
AMAD1_RS16510	COG2197	response regulator
AMAD1_RS16525	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS16535	COG1294	oxidase, subunit
AMAD1_RS16540	COG1271	oxidase subunit
AMAD1_RS16560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMAD1_RS16590	COG2199	diguanylate cyclase activity
AMAD1_RS16590	COG2203	Gaf domain
AMAD1_RS16635	COG2337	Toxic component of a toxin-antitoxin (TA) module
AMAD1_RS16665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMAD1_RS16670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMAD1_RS16670	COG2010	Cytochrome c
AMAD1_RS16675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMAD1_RS16695	COG1271	oxidase subunit
AMAD1_RS16700	COG1294	oxidase, subunit
AMAD1_RS16725	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMAD1_RS16725	COG3264	Mechanosensitive ion channel
AMAD1_RS16765	COG0730	response to heat
AMAD1_RS16770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMAD1_RS16785	COG4191	Histidine kinase
AMAD1_RS16795	COG0417	DNA replication proofreading
AMAD1_RS16805	COG0318	PFAM AMP-dependent synthetase and ligase
AMAD1_RS16850	COG1309	transcriptional regulator
AMAD1_RS16860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMAD1_RS16870	COG1573	uracil-dna glycosylase
AMAD1_RS16875	COG3300	MHYT domain
AMAD1_RS16875	COG5001	Diguanylate cyclase
AMAD1_RS16895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMAD1_RS16915	COG1983	PspC domain protein
AMAD1_RS16920	COG1842	Phage shock protein A
AMAD1_RS16930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMAD1_RS16955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMAD1_RS16965	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMAD1_RS16970	COG0204	Acyl-transferase
AMAD1_RS16975	COG0204	Acyl-transferase
AMAD1_RS16980	COG0668	transmembrane transport
AMAD1_RS16995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMAD1_RS17000	COG0733	neurotransmitter:sodium symporter activity
AMAD1_RS17015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMAD1_RS17040	COG0848	biopolymer transport protein
AMAD1_RS17055	COG0457	Tetratricopeptide repeat
AMAD1_RS17060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AMAD1_RS17070	COG1215	transferase activity, transferring glycosyl groups
AMAD1_RS17085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMAD1_RS17090	COG0702	epimerase
AMAD1_RS17105	COG5002	protein histidine kinase activity
AMAD1_RS17105	COG5001	Diguanylate cyclase
AMAD1_RS17115	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AMAD1_RS17125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMAD1_RS17135	COG0583	DNA-binding transcription factor activity
AMAD1_RS17140	COG0121	glutamine amidotransferase
AMAD1_RS17145	COG4682	membrane
AMAD1_RS17165	COG1953	Uracil, thiamine, allantoin
AMAD1_RS17170	COG4771	TonB-dependent receptor
AMAD1_RS17180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMAD1_RS17185	COG0778	Nitroreductase
AMAD1_RS17190	COG0596	Alpha beta hydrolase
AMAD1_RS17195	COG0251	oxidation-reduction process
AMAD1_RS17200	COG1335	isochorismatase
AMAD1_RS17205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMAD1_RS17210	COG1309	transcriptional regulator
AMAD1_RS17225	COG4628	conserved protein (DUF2132)
AMAD1_RS17230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMAD1_RS17240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMAD1_RS17250	COG1477	protein flavinylation
AMAD1_RS17255	COG2871	sodium ion transport
AMAD1_RS17260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMAD1_RS17265	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMAD1_RS17270	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMAD1_RS17275	COG1805	sodium ion transport
AMAD1_RS17280	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMAD1_RS17285	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMAD1_RS17290	COG0545	Peptidyl-prolyl cis-trans isomerase
AMAD1_RS17295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMAD1_RS17310	COG0039	L-malate dehydrogenase activity
AMAD1_RS17315	COG1438	arginine binding
AMAD1_RS17340	COG0572	uridine kinase
AMAD1_RS17345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMAD1_RS17370	COG2176	DNA-directed DNA polymerase activity
AMAD1_RS17375	COG1125	glycine betaine transport
AMAD1_RS17375	COG0517	IMP dehydrogenase activity
AMAD1_RS17380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMAD1_RS17390	COG2205	protein histidine kinase activity
AMAD1_RS17410	COG0189	ligase activity
AMAD1_RS17410	COG4067	protein conserved in archaea
AMAD1_RS17425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMAD1_RS17435	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMAD1_RS17440	COG0667	Aldo Keto reductase
AMAD1_RS17460	COG5001	Diguanylate cyclase
AMAD1_RS17495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMAD1_RS17505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMAD1_RS17510	COG0840	transmembrane signaling receptor activity
AMAD1_RS17550	COG2274	protein secretion by the type I secretion system
AMAD1_RS17555	COG0583	DNA-binding transcription factor activity
AMAD1_RS17580	COG1216	Glycosyl transferase, family 2
AMAD1_RS17580	COG0438	transferase activity, transferring glycosyl groups
AMAD1_RS17620	COG0457	Tetratricopeptide repeat
AMAD1_RS17655	COG1216	Glycosyl transferase, family 2
AMAD1_RS17655	COG0463	Glycosyl transferase, family 2
AMAD1_RS17740	COG4372	Transposase
AMAD1_RS17760	COG4372	Transposase
AMAD1_RS17810	COG2161	toxin-antitoxin pair type II binding
AMAD1_RS17820	COG0202	RNA polymerase activity
AMAD1_RS17845	COG0201	protein transport
AMAD1_RS17865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMAD1_RS17900	COG5002	protein histidine kinase activity
AMAD1_RS17900	COG0784	Response regulator, receiver
AMAD1_RS17920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMAD1_RS17925	COG0557	exoribonuclease II activity
AMAD1_RS17955	COG4771	TonB-dependent receptor
AMAD1_RS17970	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AMAD1_RS17985	COG0543	2 iron, 2 sulfur cluster binding
AMAD1_RS18000	COG2234	aminopeptidase activity
AMAD1_RS18010	COG4251	negative regulation of phosphorylation
AMAD1_RS18020	COG1271	oxidase subunit
AMAD1_RS18025	COG1294	oxidase, subunit
AMAD1_RS18030	COG1522	sequence-specific DNA binding
AMAD1_RS18040	COG1278	Cold shock
AMAD1_RS18045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMAD1_RS18065	COG0339	signal peptide processing
AMAD1_RS18070	COG2201	protein-glutamate methylesterase activity
AMAD1_RS18080	COG3852	Histidine kinase
AMAD1_RS18090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMAD1_RS18095	COG0243	molybdopterin cofactor binding
AMAD1_RS18100	COG1506	peptidase
AMAD1_RS18100	COG4946	Tricorn protease homolog
AMAD1_RS18100	COG0823	Involved in the tonB-independent uptake of proteins
AMAD1_RS18145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMAD1_RS18155	COG2197	response regulator
AMAD1_RS18165	COG0189	ligase activity
AMAD1_RS18185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMAD1_RS18190	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMAD1_RS18195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMAD1_RS18210	COG0281	malic enzyme
AMAD1_RS18220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMAD1_RS18250	COG0456	acetyltransferase
AMAD1_RS18260	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMAD1_RS18265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMAD1_RS18270	COG2177	Part of the ABC transporter FtsEX involved in
AMAD1_RS18275	COG2884	Cell division ATP-binding protein ftsE
AMAD1_RS18280	COG0552	protein localization to endoplasmic reticulum
AMAD1_RS18285	COG0742	ribosomal rna small subunit methyltransferase
AMAD1_RS18295	COG2095	MarC family integral membrane protein
AMAD1_RS18315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMAD1_RS18320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMAD1_RS18325	COG0617	tRNA 3'-terminal CCA addition
AMAD1_RS18330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMAD1_RS18345	COG0076	glutamate decarboxylase activity
AMAD1_RS18360	COG0842	Transport permease protein
AMAD1_RS18365	COG1131	(ABC) transporter
AMAD1_RS18370	COG0745	RESPONSE REGULATOR receiver
AMAD1_RS18375	COG2205	protein histidine kinase activity
AMAD1_RS18380	COG4774	siderophore transport
AMAD1_RS18400	COG1253	flavin adenine dinucleotide binding
AMAD1_RS18410	COG1966	Carbon starvation protein
AMAD1_RS18420	COG0657	acetylesterase activity
AMAD1_RS18435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMAD1_RS18440	COG0049	tRNA binding
AMAD1_RS18445	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMAD1_RS18450	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMAD1_RS18455	COG0085	RNA polymerase activity
AMAD1_RS18460	COG0222	ribosome binding
AMAD1_RS18465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMAD1_RS18470	COG0081	regulation of translation
AMAD1_RS18475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMAD1_RS18495	COG0250	Participates in transcription elongation, termination and antitermination
AMAD1_RS18500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMAD1_RS18510	COG1132	(ABC) transporter
AMAD1_RS18515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMAD1_RS18520	COG3590	peptidase
AMAD1_RS18530	COG0513	Belongs to the DEAD box helicase family
AMAD1_RS18535	COG0418	dihydroorotase activity
AMAD1_RS18540	COG3040	lipid binding
AMAD1_RS18545	COG4989	oxidoreductase activity
AMAD1_RS18550	COG0346	lactoylglutathione lyase activity
AMAD1_RS18555	COG0668	transmembrane transport
AMAD1_RS18575	COG0302	gtp cyclohydrolase
AMAD1_RS18585	COG2957	Belongs to the agmatine deiminase family
AMAD1_RS18590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMAD1_RS18605	COG1201	RNA secondary structure unwinding
AMAD1_RS18615	COG1793	dna ligase
AMAD1_RS18620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMAD1_RS18625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMAD1_RS18635	COG1410	methionine synthase
AMAD1_RS18635	COG0646	methionine synthase
AMAD1_RS18640	COG0625	glutathione transferase activity
AMAD1_RS18645	COG0625	glutathione transferase activity
AMAD1_RS18655	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMAD1_RS18670	COG1012	belongs to the aldehyde dehydrogenase family
AMAD1_RS18675	COG0028	Belongs to the TPP enzyme family
AMAD1_RS18685	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMAD1_RS18690	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AMAD1_RS18695	COG0330	HflC and HflK could
AMAD1_RS18700	COG0330	HflC and HflK could
AMAD1_RS18705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMAD1_RS18710	COG1923	regulation of RNA biosynthetic process
AMAD1_RS18715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMAD1_RS18730	COG0802	atpase or kinase
AMAD1_RS18735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMAD1_RS18735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMAD1_RS18740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMAD1_RS18760	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AMAD1_RS18765	COG0735	belongs to the Fur family
AMAD1_RS18785	COG0305	Participates in initiation and elongation during chromosome replication
AMAD1_RS18810	COG2258	MOSC domain
AMAD1_RS18840	COG2205	protein histidine kinase activity
AMAD1_RS18860	COG0840	transmembrane signaling receptor activity
AMAD1_RS18865	COG5002	protein histidine kinase activity
AMAD1_RS18870	COG0840	transmembrane signaling receptor activity
AMAD1_RS18895	COG1757	Na H antiporter
AMAD1_RS18900	COG1472	Belongs to the glycosyl hydrolase 3 family
AMAD1_RS18910	COG2723	6-phospho-beta-galactosidase activity
AMAD1_RS18915	COG1609	Transcriptional regulator
AMAD1_RS18920	COG0477	Major facilitator Superfamily
AMAD1_RS18920	COG2814	Major facilitator Superfamily
AMAD1_RS18925	COG4319	ketosteroid isomerase
AMAD1_RS18945	COG2375	cellular response to nickel ion
AMAD1_RS18950	COG3237	CsbD-like
AMAD1_RS18980	COG0596	Alpha beta hydrolase
AMAD1_RS18980	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMAD1_RS19000	COG3038	cytochrome b561
AMAD1_RS19010	COG1252	NADH dehydrogenase
AMAD1_RS19025	COG0583	DNA-binding transcription factor activity
AMAD1_RS19030	COG2067	long-chain fatty acid transport protein
AMAD1_RS19035	COG2130	NADP-dependent
AMAD1_RS19040	COG4251	negative regulation of phosphorylation
AMAD1_RS19040	COG5001	Diguanylate cyclase
AMAD1_RS19040	COG3706	GGDEF domain
AMAD1_RS19040	COG2203	Gaf domain
AMAD1_RS19045	COG0784	Response regulator, receiver
AMAD1_RS19045	COG2205	protein histidine kinase activity
AMAD1_RS19055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMAD1_RS19060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMAD1_RS19065	COG1349	DNA-binding transcription factor activity
AMAD1_RS19070	COG0673	inositol 2-dehydrogenase activity
AMAD1_RS19085	COG0697	spore germination
AMAD1_RS19090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMAD1_RS19095	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AMAD1_RS19100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMAD1_RS19105	COG1166	arginine decarboxylase activity
AMAD1_RS19115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMAD1_RS19195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMAD1_RS19200	COG0109	protoheme IX farnesyltransferase activity
AMAD1_RS19220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMAD1_RS19235	COG1487	ribonuclease activity
AMAD1_RS19265	COG3030	protein affecting phage T7 exclusion by the F plasmid
AMAD1_RS19270	COG1324	tolerance protein
AMAD1_RS19275	COG4232	protein-disulfide reductase activity
AMAD1_RS19280	COG0739	heme binding
AMAD1_RS19285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMAD1_RS19290	COG0511	ligase activity, forming carbon-carbon bonds
AMAD1_RS19295	COG0439	Biotin carboxylase
AMAD1_RS19345	COG0154	amidase activity
AMAD1_RS19360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMAD1_RS19365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AMAD1_RS19380	COG0151	Belongs to the GarS family
AMAD1_RS19395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMAD1_RS19400	COG3954	Phosphoribulokinase
AMAD1_RS19425	COG1501	Belongs to the glycosyl hydrolase 31 family
AMAD1_RS19435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMAD1_RS19440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMAD1_RS19450	COG3031	protein transport across the cell outer membrane
AMAD1_RS19460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMAD1_RS19465	COG1459	type II secretion system
AMAD1_RS19470	COG2165	general secretion pathway protein
AMAD1_RS19475	COG2165	general secretion pathway protein
AMAD1_RS19485	COG4795	General secretion pathway protein
AMAD1_RS19500	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AMAD1_RS19515	COG1012	belongs to the aldehyde dehydrogenase family
AMAD1_RS19525	COG1011	Hydrolase
AMAD1_RS19530	COG0494	nUDIX hydrolase
AMAD1_RS19535	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMAD1_RS19545	COG2943	transferase activity, transferring hexosyl groups
AMAD1_RS19550	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AMAD1_RS19560	COG3089	Belongs to the UPF0270 family
AMAD1_RS19565	COG0429	hydrolase of the alpha beta-hydrolase fold
AMAD1_RS19575	COG0488	(ABC) transporter
AMAD1_RS19590	COG2900	Belongs to the SlyX family
AMAD1_RS19600	COG0545	Peptidyl-prolyl cis-trans isomerase
AMAD1_RS19610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMAD1_RS19615	COG2183	response to ionizing radiation
AMAD1_RS19640	COG2207	Transcriptional regulator
AMAD1_RS19640	COG1609	Transcriptional regulator
AMAD1_RS19645	COG2211	Major facilitator Superfamily
AMAD1_RS19660	COG3693	PFAM glycoside hydrolase, family 10
AMAD1_RS19665	COG0667	Aldo Keto reductase
AMAD1_RS19670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMAD1_RS19675	COG2115	Belongs to the xylose isomerase family
AMAD1_RS19680	COG1070	Carbohydrate kinase
AMAD1_RS19695	COG1472	Belongs to the glycosyl hydrolase 3 family
AMAD1_RS19700	COG0477	Major facilitator Superfamily
AMAD1_RS19745	COG0596	Alpha beta hydrolase
AMAD1_RS19750	COG1040	competence protein
AMAD1_RS19770	COG1794	racemase activity, acting on amino acids and derivatives
AMAD1_RS19780	COG0534	Mate efflux family protein
AMAD1_RS19795	COG1999	signal sequence binding
AMAD1_RS19800	COG0109	protoheme IX farnesyltransferase activity
AMAD1_RS19805	COG1612	heme a metabolic process
AMAD1_RS19825	COG1845	cytochrome c oxidase, subunit III
AMAD1_RS19830	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AMAD1_RS19835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMAD1_RS19840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMAD1_RS19860	COG0129	dihydroxy-acid dehydratase activity
AMAD1_RS19870	COG0606	chelatase, subunit chli
AMAD1_RS19875	COG0583	DNA-binding transcription factor activity
AMAD1_RS19885	COG2814	Major facilitator Superfamily
AMAD1_RS19895	COG0729	surface antigen
AMAD1_RS19900	COG2911	Protein conserved in bacteria
AMAD1_RS19925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMAD1_RS19935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMAD1_RS19955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMAD1_RS19980	COG1228	amidohydrolase
AMAD1_RS20005	COG0425	Belongs to the sulfur carrier protein TusA family
AMAD1_RS20020	COG1561	YicC-like family, N-terminal region
AMAD1_RS20030	COG3550	peptidyl-serine autophosphorylation
AMAD1_RS20035	COG3620	sequence-specific DNA binding
AMAD1_RS20105	COG5433	transposase activity
AMAD1_RS20110	COG3119	arylsulfatase activity
AMAD1_RS20115	COG0714	Associated with various cellular activities
AMAD1_RS20130	COG2304	oxidoreductase activity
AMAD1_RS20160	COG0318	PFAM AMP-dependent synthetase and ligase
AMAD1_RS20165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMAD1_RS20175	COG1960	acyl-CoA dehydrogenase activity
AMAD1_RS20185	COG1024	Enoyl-CoA hydratase
AMAD1_RS20195	COG2801	Transposase and inactivated derivatives
AMAD1_RS20205	COG0800	Aldolase
AMAD1_RS20215	COG0129	dihydroxy-acid dehydratase activity
AMAD1_RS20225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMAD1_RS20230	COG1737	Transcriptional regulator
AMAD1_RS20235	COG0469	pyruvate kinase activity
AMAD1_RS20265	COG3177	Filamentation induced by cAMP protein fic
AMAD1_RS20275	COG1609	Transcriptional regulator
AMAD1_RS20290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMAD1_RS20290	COG2199	diguanylate cyclase activity
AMAD1_RS20315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMAD1_RS20335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMAD1_RS20340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMAD1_RS20360	COG1475	DNA binding
AMAD1_RS20365	COG1192	Involved in chromosome partitioning
AMAD1_RS20390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMAD1_RS20405	COG0706	membrane insertase activity
AMAD1_RS20410	COG0594	ribonuclease P activity
AMAD1_RS20515	COG2818	Glycosylase
AMAD1_RS21120	COG1129	ABC transporter
AMAD1_RS21120	COG0842	Transport permease protein
AMAD1_RS21200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMAD1_RS21440	COG2814	Major facilitator Superfamily
AMAD1_RS21515	COG3250	beta-galactosidase activity
AMAD1_RS21645	COG3267	Type II secretory pathway component ExeA
AMAD1_RS21645	COG3409	Peptidoglycan-binding domain 1 protein
AMAD1_RS21665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMAD1_RS21670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMAD1_RS21850	COG1216	Glycosyl transferase, family 2
AMAD1_RS21895	COG3706	GGDEF domain
AMAD1_RS21910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMAD1_RS21925	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMAD1_RS21930	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity