locus-tag	class	description
BM526_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BM526_RS00020	COG0187	DNA topoisomerase II activity
BM526_RS00050	COG2818	Glycosylase
BM526_RS00060	COG3078	GTPase activator activity
BM526_RS00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM526_RS00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM526_RS00085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BM526_RS00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BM526_RS00095	COG0569	domain protein
BM526_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM526_RS00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM526_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM526_RS00120	COG0758	DNA mediated transformation
BM526_RS00135	COG0009	L-threonylcarbamoyladenylate synthase
BM526_RS00140	COG0408	coproporphyrinogen oxidase activity
BM526_RS00145	COG3047	cAMP biosynthetic process
BM526_RS00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BM526_RS00230	COG2234	aminopeptidase activity
BM526_RS00235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM526_RS00235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_RS00250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BM526_RS00275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_RS00305	COG3642	lipopolysaccharide core region biosynthetic process
BM526_RS00310	COG0859	PFAM glycosyl transferase family 9
BM526_RS00340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_RS00355	COG3161	chorismate lyase activity
BM526_RS00360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BM526_RS00380	COG0210	DNA helicase
BM526_RS00410	COG1757	Na H antiporter
BM526_RS00425	COG1959	2 iron, 2 sulfur cluster binding
BM526_RS00430	COG0730	response to heat
BM526_RS00460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM526_RS00465	COG4988	ABC transporter
BM526_RS00475	COG1271	oxidase subunit
BM526_RS00480	COG0425	Belongs to the sulfur carrier protein TusA family
BM526_RS00480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_RS00490	COG0450	alkyl hydroperoxide reductase
BM526_RS00495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_RS00500	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_RS00520	COG1024	Enoyl-CoA hydratase
BM526_RS00525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM526_RS00535	COG1960	acyl-CoA dehydrogenase activity
BM526_RS00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS00590	COG0842	Transport permease protein
BM526_RS00590	COG1129	ABC transporter
BM526_RS00595	COG0842	Transport permease protein
BM526_RS00605	COG4771	TonB-dependent receptor
BM526_RS00620	COG0583	DNA-binding transcription factor activity
BM526_RS00630	COG3106	COG3106 Predicted ATPase
BM526_RS00645	COG2184	nucleotidyltransferase activity
BM526_RS00650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BM526_RS00665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM526_RS00670	COG0352	thiamine-phosphate diphosphorylase activity
BM526_RS00680	COG3071	HemY protein
BM526_RS00685	COG2959	enzyme of heme biosynthesis
BM526_RS00695	COG0181	hydroxymethylbilane synthase activity
BM526_RS00710	COG0194	GDP metabolic process
BM526_RS00720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM526_RS00730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM526_RS00735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BM526_RS00745	COG0678	peroxiredoxin activity
BM526_RS00760	COG1178	ABC-type Fe3 transport system permease component
BM526_RS00765	COG3842	ATPase activity
BM526_RS00770	COG0668	transmembrane transport
BM526_RS00775	COG2081	HI0933 family
BM526_RS00785	COG2200	EAL domain
BM526_RS00790	COG0583	DNA-binding transcription factor activity
BM526_RS00815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS00830	COG0427	acetyl-CoA hydrolase
BM526_RS00835	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM526_RS00850	COG0840	transmembrane signaling receptor activity
BM526_RS00860	COG3064	Membrane
BM526_RS00870	COG5002	protein histidine kinase activity
BM526_RS00870	COG5001	Diguanylate cyclase
BM526_RS00885	COG0514	ATP-dependent DNA helicase (RecQ)
BM526_RS00890	COG2239	Acts as a magnesium transporter
BM526_RS00895	COG2962	Rard protein
BM526_RS00905	COG0210	DNA helicase
BM526_RS00915	COG1011	Hydrolase
BM526_RS00920	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BM526_RS00930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BM526_RS00935	COG0019	diaminopimelate decarboxylase activity
BM526_RS00965	COG0163	prenyltransferase activity
BM526_RS00970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM526_RS00980	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BM526_RS01005	COG1077	Cell shape determining protein MreB Mrl
BM526_RS01020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BM526_RS01025	COG2814	Major facilitator Superfamily
BM526_RS01030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_RS01060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BM526_RS01075	COG0629	single-stranded DNA binding
BM526_RS01105	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_RS01130	COG1349	DNA-binding transcription factor activity
BM526_RS01200	COG3267	Type II secretory pathway component ExeA
BM526_RS01200	COG3409	Peptidoglycan-binding domain 1 protein
BM526_RS01210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_RS01215	COG1459	type II secretion system
BM526_RS01225	COG2165	general secretion pathway protein
BM526_RS01230	COG2165	general secretion pathway protein
BM526_RS01260	COG1077	Cell shape determining protein MreB Mrl
BM526_RS01265	COG1792	Involved in formation and maintenance of cell shape
BM526_RS01270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BM526_RS01280	COG1530	ribonuclease E activity
BM526_RS01290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_RS01295	COG0312	modulator of DNA gyrase
BM526_RS01300	COG3028	Belongs to the UPF0307 family
BM526_RS01305	COG0312	modulator of DNA gyrase
BM526_RS01320	COG0745	RESPONSE REGULATOR receiver
BM526_RS01325	COG4191	Histidine kinase
BM526_RS01325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_RS01330	COG0297	glycogen (starch) synthase activity
BM526_RS01340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BM526_RS01345	COG0596	Alpha beta hydrolase
BM526_RS01390	COG0745	RESPONSE REGULATOR receiver
BM526_RS01400	COG0835	chemotaxis
BM526_RS01415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM526_RS01430	COG0745	RESPONSE REGULATOR receiver
BM526_RS01435	COG0643	Histidine kinase
BM526_RS01435	COG2198	Histidine kinase
BM526_RS01440	COG0835	chemotaxis
BM526_RS01460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM526_RS01535	COG0673	inositol 2-dehydrogenase activity
BM526_RS01545	COG2211	Major facilitator Superfamily
BM526_RS01550	COG1082	Xylose isomerase domain protein TIM barrel
BM526_RS01570	COG1454	alcohol dehydrogenase
BM526_RS01600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_RS01620	COG0089	rRNA binding
BM526_RS01630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BM526_RS01640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BM526_RS01655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BM526_RS01660	COG0438	transferase activity, transferring glycosyl groups
BM526_RS01670	COG1519	Transferase
BM526_RS01690	COG0840	transmembrane signaling receptor activity
BM526_RS01705	COG0788	formyltetrahydrofolate deformylase activity
BM526_RS01715	COG1643	Atp-dependent helicase
BM526_RS01725	COG2951	lytic endotransglycosylase activity
BM526_RS01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM526_RS01740	COG2354	Protein conserved in bacteria
BM526_RS01765	COG0004	ammonium transporteR
BM526_RS01770	COG0405	Gamma-glutamyltransferase
BM526_RS01775	COG2837	iron assimilation
BM526_RS01790	COG0540	Belongs to the ATCase OTCase family
BM526_RS01815	COG0784	Response regulator, receiver
BM526_RS01815	COG5002	protein histidine kinase activity
BM526_RS01815	COG2205	protein histidine kinase activity
BM526_RS01830	COG3300	MHYT domain
BM526_RS01830	COG5001	Diguanylate cyclase
BM526_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
BM526_RS01850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM526_RS01865	COG0180	Tryptophanyl-tRNA synthetase
BM526_RS01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BM526_RS01890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BM526_RS01900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BM526_RS01935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BM526_RS01940	COG0281	malic enzyme
BM526_RS01950	COG0625	glutathione transferase activity
BM526_RS01960	COG0753	catalase activity
BM526_RS01985	COG3300	MHYT domain
BM526_RS01985	COG5001	Diguanylate cyclase
BM526_RS01990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BM526_RS01990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BM526_RS02000	COG0137	argininosuccinate synthase activity
BM526_RS02020	COG1803	Methylglyoxal synthase
BM526_RS02030	COG0745	RESPONSE REGULATOR receiver
BM526_RS02035	COG2205	protein histidine kinase activity
BM526_RS02040	COG2267	carboxylic ester hydrolase activity
BM526_RS02045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BM526_RS02055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BM526_RS02065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM526_RS02070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_RS02075	COG4942	peptidase
BM526_RS02080	COG2861	carbohydrate metabolic process
BM526_RS02105	COG1162	GTPase activity
BM526_RS02110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BM526_RS02130	COG0457	Tetratricopeptide repeat
BM526_RS02145	COG0028	Belongs to the TPP enzyme family
BM526_RS02165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BM526_RS02170	COG0805	protein transport
BM526_RS02180	COG0084	hydrolase, TatD family'
BM526_RS02185	COG2203	Gaf domain
BM526_RS02185	COG5001	Diguanylate cyclase
BM526_RS02185	COG3706	GGDEF domain
BM526_RS02185	COG4251	negative regulation of phosphorylation
BM526_RS02195	COG0248	Ppx GppA phosphatase
BM526_RS02200	COG0513	Belongs to the DEAD box helicase family
BM526_RS02205	COG3118	belongs to the thioredoxin family
BM526_RS02210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BM526_RS02215	COG1473	amidohydrolase
BM526_RS02220	COG5002	protein histidine kinase activity
BM526_RS02220	COG0784	Response regulator, receiver
BM526_RS02225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BM526_RS02230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BM526_RS02235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BM526_RS02250	COG0783	Belongs to the Dps family
BM526_RS02255	COG2133	pyrroloquinoline quinone binding
BM526_RS02260	COG1506	peptidase
BM526_RS02260	COG4946	Tricorn protease homolog
BM526_RS02260	COG0823	Involved in the tonB-independent uptake of proteins
BM526_RS02270	COG3118	belongs to the thioredoxin family
BM526_RS02285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BM526_RS02295	COG1012	belongs to the aldehyde dehydrogenase family
BM526_RS02315	COG1757	Na H antiporter
BM526_RS02330	COG3876	Protein conserved in bacteria
BM526_RS02335	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM526_RS02345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BM526_RS02355	COG0346	lactoylglutathione lyase activity
BM526_RS02380	COG2824	Alkylphosphonate utilization operon protein PhnA
BM526_RS02385	COG0454	-acetyltransferase
BM526_RS02595	COG0183	Belongs to the thiolase family
BM526_RS02600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_RS02600	COG1024	Enoyl-CoA hydratase
BM526_RS02610	COG0006	proline dipeptidase activity
BM526_RS02620	COG0142	geranyltranstransferase activity
BM526_RS02650	COG1388	LysM domain
BM526_RS02650	COG4942	peptidase
BM526_RS02655	COG1238	metal cluster binding
BM526_RS02665	COG0585	pseudouridine synthase activity
BM526_RS02670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BM526_RS02680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BM526_RS02690	COG0840	transmembrane signaling receptor activity
BM526_RS02705	COG5002	protein histidine kinase activity
BM526_RS02730	COG0494	nUDIX hydrolase
BM526_RS02735	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BM526_RS02740	COG0730	response to heat
BM526_RS02745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BM526_RS02750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BM526_RS02755	COG2201	protein-glutamate methylesterase activity
BM526_RS02785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BM526_RS02800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BM526_RS02810	COG1648	precorrin-2 dehydrogenase activity
BM526_RS02810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM526_RS02815	COG0513	Belongs to the DEAD box helicase family
BM526_RS02830	COG1538	Outer membrane efflux protein
BM526_RS02835	COG0494	nUDIX hydrolase
BM526_RS02845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BM526_RS02850	COG3150	esterase
BM526_RS02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_RS02890	COG1509	lysine 2,3-aminomutase activity
BM526_RS02895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM526_RS02900	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BM526_RS02915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM526_RS02920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM526_RS02935	COG0271	Belongs to the BolA IbaG family
BM526_RS02950	COG3707	response regulator
BM526_RS02965	COG0659	secondary active sulfate transmembrane transporter activity
BM526_RS02975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM526_RS02985	COG0243	molybdopterin cofactor binding
BM526_RS02990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM526_RS02990	COG1648	precorrin-2 dehydrogenase activity
BM526_RS02995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM526_RS03005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM526_RS03005	COG1116	anion transmembrane transporter activity
BM526_RS03015	COG1116	anion transmembrane transporter activity
BM526_RS03030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM526_RS03035	COG4206	TonB-dependent receptor
BM526_RS03040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BM526_RS03045	COG0348	domain, Protein
BM526_RS03060	COG1960	acyl-CoA dehydrogenase activity
BM526_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS03075	COG4948	Mandelate Racemase Muconate Lactonizing
BM526_RS03090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS03095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_RS03120	COG0358	DNA primase activity
BM526_RS03125	COG1610	YqeY-like protein
BM526_RS03145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BM526_RS03150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM526_RS03165	COG0537	adenosine 5'-monophosphoramidase activity
BM526_RS03180	COG3135	benzoate transporter
BM526_RS03185	COG1396	sequence-specific DNA binding
BM526_RS03190	COG2974	May be involved in recombination
BM526_RS03195	COG4191	Histidine kinase
BM526_RS03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_RS03200	COG0745	RESPONSE REGULATOR receiver
BM526_RS03205	COG5002	protein histidine kinase activity
BM526_RS03230	COG0811	peptide transport
BM526_RS03235	COG0811	peptide transport
BM526_RS03240	COG0848	biopolymer transport protein
BM526_RS03245	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BM526_RS03255	COG3437	response regulator, receiver
BM526_RS03260	COG0784	Response regulator, receiver
BM526_RS03260	COG2205	protein histidine kinase activity
BM526_RS03260	COG5002	protein histidine kinase activity
BM526_RS03275	COG2133	pyrroloquinoline quinone binding
BM526_RS03285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_RS03315	COG0527	aspartate kinase activity
BM526_RS03325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BM526_RS03330	COG2967	ApaG domain
BM526_RS03340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BM526_RS03345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_RS03350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BM526_RS03355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BM526_RS03365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM526_RS03385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BM526_RS03400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM526_RS03405	COG3956	TIGRFAM MazG family protein
BM526_RS03430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BM526_RS03435	COG0723	plastoquinol--plastocyanin reductase activity
BM526_RS03440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BM526_RS03445	COG2857	Cytochrome c1
BM526_RS03450	COG0625	glutathione transferase activity
BM526_RS03455	COG2969	positive regulation of protein catabolic process
BM526_RS03470	COG0745	RESPONSE REGULATOR receiver
BM526_RS03475	COG2239	Acts as a magnesium transporter
BM526_RS03480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM526_RS03500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BM526_RS03505	COG1137	ATPase activity
BM526_RS03510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BM526_RS03520	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BM526_RS03535	COG1127	ABC transporter
BM526_RS03540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM526_RS03545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM526_RS03550	COG2854	intermembrane phospholipid transfer
BM526_RS03560	COG5007	Belongs to the BolA IbaG family
BM526_RS03570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM526_RS03575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM526_RS03585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM526_RS03620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_RS03635	COG4771	TonB-dependent receptor
BM526_RS03640	COG0697	spore germination
BM526_RS03650	COG0784	Response regulator, receiver
BM526_RS03650	COG2205	protein histidine kinase activity
BM526_RS03675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM526_RS03685	COG0126	phosphoglycerate kinase activity
BM526_RS03690	COG3588	fructose-bisphosphate aldolase
BM526_RS03700	COG1506	peptidase
BM526_RS03700	COG0823	Involved in the tonB-independent uptake of proteins
BM526_RS03700	COG4946	Tricorn protease homolog
BM526_RS03705	COG0248	Ppx GppA phosphatase
BM526_RS03710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BM526_RS03720	COG0573	inorganic phosphate transmembrane transporter activity
BM526_RS03730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BM526_RS03740	COG0306	phosphate transporter
BM526_RS03750	COG0583	DNA-binding transcription factor activity
BM526_RS03760	COG1272	protein, Hemolysin III
BM526_RS03765	COG1846	Transcriptional regulator
BM526_RS03770	COG1764	response to oxidative stress
BM526_RS03785	COG1739	Uncharacterized protein family UPF0029
BM526_RS03805	COG0583	DNA-binding transcription factor activity
BM526_RS03810	COG4989	oxidoreductase activity
BM526_RS03825	COG0420	3'-5' exonuclease activity
BM526_RS03830	COG0419	ATPase involved in DNA repair
BM526_RS03840	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BM526_RS03855	COG2188	Transcriptional regulator
BM526_RS03860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BM526_RS03865	COG2986	histidine ammonia-lyase
BM526_RS03890	COG0488	(ABC) transporter
BM526_RS03915	COG0668	transmembrane transport
BM526_RS03960	COG1346	cytolysis
BM526_RS03990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM526_RS04000	COG0513	Belongs to the DEAD box helicase family
BM526_RS04010	COG3409	Peptidoglycan-binding domain 1 protein
BM526_RS04010	COG3267	Type II secretory pathway component ExeA
BM526_RS04025	COG0066	3-isopropylmalate dehydratase activity
BM526_RS04035	COG0473	3-isopropylmalate dehydrogenase activity
BM526_RS04040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BM526_RS04065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BM526_RS04080	COG4555	ABC transporter
BM526_RS04085	COG1668	transmembrane transport
BM526_RS04100	COG4133	protoheme IX ABC transporter activity
BM526_RS04105	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_RS04110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_RS04115	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_RS04125	COG1138	Cytochrome C-type biogenesis protein
BM526_RS04130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM526_RS04145	COG2853	Lipoprotein
BM526_RS04150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM526_RS04170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM526_RS04175	COG1596	polysaccharide export
BM526_RS04175	COG1555	photosystem II stabilization
BM526_RS04180	COG0473	3-isopropylmalate dehydrogenase activity
BM526_RS04195	COG1611	Belongs to the LOG family
BM526_RS04205	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM526_RS04205	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM526_RS04260	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BM526_RS04265	COG0024	Methionine aminopeptidase
BM526_RS04270	COG0052	Belongs to the universal ribosomal protein uS2 family
BM526_RS04280	COG0528	UMP kinase activity
BM526_RS04295	COG0575	Belongs to the CDS family
BM526_RS04320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM526_RS04340	COG0587	DNA-directed DNA polymerase activity
BM526_RS04345	COG0825	malonyl-CoA metabolic process
BM526_RS04350	COG0037	tRNA processing
BM526_RS04380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BM526_RS04380	COG0047	phosphoribosylformylglycinamidine synthase activity
BM526_RS04385	COG2840	Smr protein MutS2
BM526_RS04415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS04420	COG2197	response regulator
BM526_RS04460	COG0784	Response regulator, receiver
BM526_RS04460	COG0835	chemotaxis
BM526_RS04465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM526_RS04470	COG1815	bacterial-type flagellum-dependent cell motility
BM526_RS04490	COG4787	bacterial-type flagellum-dependent cell motility
BM526_RS04510	COG1705	Flagellar rod assembly protein muramidase FlgJ
BM526_RS04510	COG3951	Flagellar rod assembly protein muramidase FlgJ
BM526_RS04515	COG1256	bacterial-type flagellum assembly
BM526_RS04540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_RS04545	COG1334	flagellar protein FlaG
BM526_RS04550	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BM526_RS04575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM526_RS04585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BM526_RS04590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM526_RS04600	COG1215	transferase activity, transferring glycosyl groups
BM526_RS04605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM526_RS04610	COG1086	Polysaccharide biosynthesis protein
BM526_RS04625	COG3475	LICD family
BM526_RS04630	COG2089	acid synthase
BM526_RS04640	COG1083	cytidylyl-transferase
BM526_RS04650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_RS04675	COG1677	Flagellar hook-basal body complex protein FliE
BM526_RS04680	COG1766	The M ring may be actively involved in energy transduction
BM526_RS04685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BM526_RS04735	COG1987	bacterial-type flagellum assembly
BM526_RS04750	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM526_RS04775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BM526_RS04780	COG2198	Histidine kinase
BM526_RS04780	COG0784	Response regulator, receiver
BM526_RS04780	COG0643	Histidine kinase
BM526_RS04790	COG1192	Involved in chromosome partitioning
BM526_RS04800	COG0835	chemotaxis
BM526_RS04815	COG1410	methionine synthase
BM526_RS04815	COG0646	methionine synthase
BM526_RS04820	COG0646	methionine synthase
BM526_RS04820	COG1410	methionine synthase
BM526_RS04830	COG3123	guanosine phosphorylase activity
BM526_RS04840	COG0583	DNA-binding transcription factor activity
BM526_RS04845	COG0583	DNA-binding transcription factor activity
BM526_RS04855	COG0659	secondary active sulfate transmembrane transporter activity
BM526_RS04870	COG3590	peptidase
BM526_RS04880	COG2137	regulation of response to DNA damage stimulus
BM526_RS04885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM526_RS04915	COG0511	ligase activity, forming carbon-carbon bonds
BM526_RS04915	COG5016	pyruvate
BM526_RS04920	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BM526_RS04925	COG4172	Belongs to the ABC transporter superfamily
BM526_RS04935	COG4171	peptide transport system, permease
BM526_RS04940	COG4168	peptide transport system, permease
BM526_RS04945	COG0747	negative chemotaxis
BM526_RS04950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BM526_RS04955	COG1842	Phage shock protein A
BM526_RS04985	COG0625	glutathione transferase activity
BM526_RS04990	COG1522	sequence-specific DNA binding
BM526_RS05055	COG0811	peptide transport
BM526_RS05060	COG0811	peptide transport
BM526_RS05065	COG0848	biopolymer transport protein
BM526_RS05080	COG1444	tRNA N-acetyltransferase activity
BM526_RS05120	COG0456	acetyltransferase
BM526_RS05135	COG0583	DNA-binding transcription factor activity
BM526_RS05140	COG2814	Major facilitator Superfamily
BM526_RS05145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_RS05150	COG0656	L-ascorbic acid biosynthetic process
BM526_RS05160	COG3706	GGDEF domain
BM526_RS05195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM526_RS05225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BM526_RS05225	COG0543	2 iron, 2 sulfur cluster binding
BM526_RS05240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BM526_RS05245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM526_RS05250	COG0564	pseudouridine synthase activity
BM526_RS05260	COG0612	Peptidase, M16
BM526_RS05265	COG2918	glutathione biosynthetic process
BM526_RS05285	COG2840	Smr protein MutS2
BM526_RS05290	COG2890	protein-(glutamine-N5) methyltransferase activity
BM526_RS05305	COG2719	SpoVR family
BM526_RS05310	COG2718	Belongs to the UPF0229 family
BM526_RS05315	COG2766	serine protein kinase
BM526_RS05320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BM526_RS05325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BM526_RS05330	COG4771	TonB-dependent receptor
BM526_RS05355	COG0450	alkyl hydroperoxide reductase
BM526_RS05365	COG2885	chlorophyll binding
BM526_RS05370	COG0584	glycerophosphoryl diester phosphodiesterase
BM526_RS05375	COG0346	lactoylglutathione lyase activity
BM526_RS05380	COG1278	Cold shock
BM526_RS05395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BM526_RS05400	COG4660	Part of a membrane complex involved in electron transport
BM526_RS05405	COG4659	FMN binding
BM526_RS05410	COG4658	electron transport chain
BM526_RS05415	COG4656	Part of a membrane complex involved in electron transport
BM526_RS05420	COG2878	Part of a membrane complex involved in electron transport
BM526_RS05425	COG4657	Part of a membrane complex involved in electron transport
BM526_RS05440	COG0534	Mate efflux family protein
BM526_RS05445	COG0556	nucleotide-excision repair
BM526_RS05460	COG0602	queuosine metabolic process
BM526_RS05470	COG0367	asparagine synthase
BM526_RS05495	COG3273	potassium ion transport
BM526_RS05495	COG0471	metal ion transport
BM526_RS05510	COG0529	Catalyzes the synthesis of activated sulfate
BM526_RS05515	COG0175	sulfate reduction
BM526_RS05520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_RS05525	COG3706	GGDEF domain
BM526_RS05550	COG2304	oxidoreductase activity
BM526_RS05570	COG0714	Associated with various cellular activities
BM526_RS05580	COG1024	Enoyl-CoA hydratase
BM526_RS05580	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_RS05595	COG1025	Belongs to the peptidase M16 family
BM526_RS05600	COG2062	phosphohistidine phosphatase, SixA
BM526_RS05610	COG4536	flavin adenine dinucleotide binding
BM526_RS05615	COG4137	Cytochrome C assembly protein
BM526_RS05620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM526_RS05665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS05670	COG1132	(ABC) transporter
BM526_RS05685	COG0228	four-way junction DNA binding
BM526_RS05690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BM526_RS05695	COG0336	Belongs to the RNA methyltransferase TrmD family
BM526_RS05700	COG0335	large ribosomal subunit rRNA binding
BM526_RS05705	COG2860	membrane
BM526_RS05715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM526_RS05720	COG0287	Prephenate dehydrogenase
BM526_RS05720	COG1605	Chorismate mutase
BM526_RS05725	COG0077	Prephenate dehydratase
BM526_RS05725	COG1605	Chorismate mutase
BM526_RS05730	COG0745	RESPONSE REGULATOR receiver
BM526_RS05735	COG0023	Translation Initiation Factor
BM526_RS05765	COG2205	protein histidine kinase activity
BM526_RS05775	COG2204	response regulator
BM526_RS05780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_RS05795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BM526_RS05800	COG0494	nUDIX hydrolase
BM526_RS05805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BM526_RS05810	COG0632	four-way junction helicase activity
BM526_RS05815	COG2255	four-way junction helicase activity
BM526_RS05820	COG0824	Thioesterase
BM526_RS05825	COG0811	peptide transport
BM526_RS05840	COG0823	Involved in the tonB-independent uptake of proteins
BM526_RS05845	COG2885	chlorophyll binding
BM526_RS05850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BM526_RS05870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BM526_RS05885	COG4667	esterase of the alpha-beta hydrolase superfamily
BM526_RS05890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM526_RS05900	COG0784	Response regulator, receiver
BM526_RS05900	COG2205	protein histidine kinase activity
BM526_RS05915	COG0300	oxidoreductase activity
BM526_RS05920	COG3038	cytochrome b561
BM526_RS05950	COG0583	DNA-binding transcription factor activity
BM526_RS05955	COG1064	alcohol dehydrogenase
BM526_RS05960	COG1451	nucleotide metabolic process
BM526_RS05965	COG0517	IMP dehydrogenase activity
BM526_RS05970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_RS05980	COG1309	transcriptional regulator
BM526_RS05985	COG4774	siderophore transport
BM526_RS06005	COG3706	GGDEF domain
BM526_RS06015	COG3008	intermembrane lipid transfer
BM526_RS06015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM526_RS06020	COG2995	paraquat-inducible protein a
BM526_RS06040	COG2207	Transcriptional regulator
BM526_RS06045	COG0017	Asparaginyl-tRNA synthetase
BM526_RS06060	COG0189	ligase activity
BM526_RS06090	COG0156	8-amino-7-oxononanoate synthase activity
BM526_RS06095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_RS06105	COG3340	Belongs to the peptidase S51 family
BM526_RS06110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BM526_RS06115	COG4139	cobalamin transport
BM526_RS06120	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BM526_RS06125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BM526_RS06140	COG5265	(ABC) transporter
BM526_RS06145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM526_RS06155	COG0745	RESPONSE REGULATOR receiver
BM526_RS06175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM526_RS06220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_RS06235	COG2755	lipolytic protein G-D-S-L family
BM526_RS06240	COG4181	ATPase activity
BM526_RS06245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BM526_RS06250	COG1090	epimerase
BM526_RS06255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM526_RS06260	COG0628	permease
BM526_RS06285	COG2350	Protein conserved in bacteria
BM526_RS06290	COG0159	tryptophan synthase activity
BM526_RS06300	COG0135	phosphoribosylanthranilate isomerase activity
BM526_RS06300	COG0134	indole-3-glycerol-phosphate synthase activity
BM526_RS06305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM526_RS06315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BM526_RS06320	COG0613	PHP domain protein
BM526_RS06325	COG0009	L-threonylcarbamoyladenylate synthase
BM526_RS06335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BM526_RS06345	COG0656	L-ascorbic acid biosynthetic process
BM526_RS06350	COG0110	maltose O-acetyltransferase activity
BM526_RS06360	COG2733	membrane
BM526_RS06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS06385	COG0500	methyltransferase
BM526_RS06390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_RS06395	COG0497	DNA recombination
BM526_RS06400	COG0783	Belongs to the Dps family
BM526_RS06405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BM526_RS06410	COG1454	alcohol dehydrogenase
BM526_RS06415	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS06425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BM526_RS06430	COG2610	gluconate transmembrane transporter activity
BM526_RS06450	COG2198	Histidine kinase
BM526_RS06450	COG0784	Response regulator, receiver
BM526_RS06450	COG2205	protein histidine kinase activity
BM526_RS06470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM526_RS06480	COG0484	heat shock protein binding
BM526_RS06485	COG3909	cytochrome
BM526_RS06505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BM526_RS06510	COG0505	Belongs to the CarA family
BM526_RS06515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BM526_RS06520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM526_RS06545	COG0280	phosphate acetyltransferase
BM526_RS06545	COG0857	belongs to the CobB CobQ family
BM526_RS06550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BM526_RS06555	COG4535	Mg2 and Co2 transporter CorC
BM526_RS06565	COG1702	phosphate starvation-inducible protein PhoH
BM526_RS06575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_RS06605	COG1607	acyl-coa hydrolase
BM526_RS06610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM526_RS06620	COG1115	amino acid carrier protein
BM526_RS06670	COG0012	GTP binding
BM526_RS06685	COG1064	alcohol dehydrogenase
BM526_RS06700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BM526_RS06710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BM526_RS06715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BM526_RS06720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BM526_RS06730	COG2890	protein-(glutamine-N5) methyltransferase activity
BM526_RS06735	COG3437	response regulator, receiver
BM526_RS06735	COG0784	Response regulator, receiver
BM526_RS06745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BM526_RS06755	COG0583	DNA-binding transcription factor activity
BM526_RS06765	COG2363	Small membrane protein
BM526_RS06780	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BM526_RS06785	COG0515	serine threonine protein kinase
BM526_RS06790	COG2116	formate transmembrane transporter activity
BM526_RS06805	COG0714	Associated with various cellular activities
BM526_RS06810	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BM526_RS06815	COG0033	Phosphoglucomutase
BM526_RS06820	COG0058	SHG alpha-glucan phosphorylase activity
BM526_RS06830	COG2988	succinylglutamate desuccinylase activity
BM526_RS06865	COG1393	Belongs to the ArsC family
BM526_RS06890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BM526_RS06915	COG2080	2 iron, 2 sulfur cluster binding
BM526_RS06930	COG5001	Diguanylate cyclase
BM526_RS06930	COG3300	MHYT domain
BM526_RS06955	COG2249	NAD(P)H dehydrogenase (quinone) activity
BM526_RS06975	COG1733	regulation of RNA biosynthetic process
BM526_RS06980	COG5002	protein histidine kinase activity
BM526_RS06980	COG5001	Diguanylate cyclase
BM526_RS06980	COG3447	MASE1 domain protein
BM526_RS06990	COG0402	S-adenosylhomocysteine deaminase activity
BM526_RS06995	COG2351	hydroxyisourate hydrolase activity
BM526_RS07010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM526_RS07020	COG1309	transcriptional regulator
BM526_RS07035	COG2252	PERMEase
BM526_RS07040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BM526_RS07060	COG0784	Response regulator, receiver
BM526_RS07060	COG2205	protein histidine kinase activity
BM526_RS07075	COG2233	PERMEase
BM526_RS07095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM526_RS07100	COG0730	response to heat
BM526_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS07145	COG3001	Fructosamine kinase
BM526_RS07155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BM526_RS07170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BM526_RS07170	COG0662	Cupin 2, conserved barrel domain protein
BM526_RS07175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM526_RS07185	COG1596	polysaccharide export
BM526_RS07190	COG0489	protein tyrosine kinase activity
BM526_RS07195	COG4464	protein tyrosine phosphatase activity
BM526_RS07230	COG0297	glycogen (starch) synthase activity
BM526_RS07300	COG2246	polysaccharide biosynthetic process
BM526_RS07305	COG0463	Glycosyl transferase, family 2
BM526_RS07320	COG2963	transposase activity
BM526_RS07350	COG0072	phenylalanine-tRNA ligase activity
BM526_RS07350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_RS07375	COG1472	Belongs to the glycosyl hydrolase 3 family
BM526_RS07380	COG2096	Adenosyltransferase
BM526_RS07390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM526_RS07400	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM526_RS07425	COG0708	Exodeoxyribonuclease III
BM526_RS07460	COG2814	Major facilitator Superfamily
BM526_RS07495	COG4770	biotin carboxylase activity
BM526_RS07500	COG1024	Enoyl-CoA hydratase
BM526_RS07505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM526_RS07510	COG1960	acyl-CoA dehydrogenase activity
BM526_RS07515	COG0789	Transcriptional regulator
BM526_RS07520	COG0183	Belongs to the thiolase family
BM526_RS07535	COG3706	GGDEF domain
BM526_RS07545	COG2925	Exonuclease
BM526_RS07595	COG1643	Atp-dependent helicase
BM526_RS07615	COG0604	alcohol dehydrogenase
BM526_RS07615	COG3321	synthase
BM526_RS07620	COG0328	RNA-DNA hybrid ribonuclease activity
BM526_RS07625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM526_RS07655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BM526_RS07660	COG1136	(ABC) transporter
BM526_RS07665	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM526_RS07680	COG3724	N-succinylarginine dihydrolase activity
BM526_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BM526_RS07705	COG0746	molybdenum cofactor guanylyltransferase activity
BM526_RS07710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BM526_RS07715	COG0243	molybdopterin cofactor binding
BM526_RS07720	COG2153	protein acetylation
BM526_RS07735	COG1530	ribonuclease E activity
BM526_RS07755	COG1399	metal-binding, possibly nucleic acid-binding protein
BM526_RS07765	COG0416	fatty acid biosynthetic process
BM526_RS07770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BM526_RS07775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BM526_RS07785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM526_RS07790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM526_RS07795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BM526_RS07800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BM526_RS07815	COG0084	hydrolase, TatD family'
BM526_RS07825	COG0702	epimerase
BM526_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS07855	COG0596	Alpha beta hydrolase
BM526_RS07865	COG0183	Belongs to the thiolase family
BM526_RS07870	COG1960	acyl-CoA dehydrogenase activity
BM526_RS07890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_RS07900	COG0246	Mannitol dehydrogenase
BM526_RS07925	COG0668	transmembrane transport
BM526_RS07930	COG4771	TonB-dependent receptor
BM526_RS07960	COG3437	response regulator, receiver
BM526_RS07970	COG0195	Participates in both transcription termination and antitermination
BM526_RS07985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BM526_RS08000	COG3300	MHYT domain
BM526_RS08000	COG5001	Diguanylate cyclase
BM526_RS08005	COG1187	pseudouridine synthase activity
BM526_RS08015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_RS08015	COG3153	acetyltransferase
BM526_RS08090	COG1032	radical SAM domain protein
BM526_RS08105	COG4771	TonB-dependent receptor
BM526_RS08110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_RS08120	COG4134	Bacterial extracellular solute-binding protein
BM526_RS08130	COG4136	ATPase activity
BM526_RS08135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BM526_RS08155	COG4251	negative regulation of phosphorylation
BM526_RS08155	COG5001	Diguanylate cyclase
BM526_RS08155	COG2203	Gaf domain
BM526_RS08155	COG3706	GGDEF domain
BM526_RS08175	COG0583	DNA-binding transcription factor activity
BM526_RS08195	COG1131	(ABC) transporter
BM526_RS08210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM526_RS08215	COG0385	Bile acid
BM526_RS08245	COG0582	viral genome integration into host DNA
BM526_RS08320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM526_RS08325	COG0732	type I restriction modification DNA specificity domain
BM526_RS08340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BM526_RS08385	COG1902	pentaerythritol trinitrate reductase activity
BM526_RS08395	COG2867	negative regulation of translational initiation
BM526_RS08400	COG2914	Belongs to the UPF0125 (RnfH) family
BM526_RS08410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_RS08415	COG4771	TonB-dependent receptor
BM526_RS08420	COG0457	Tetratricopeptide repeat
BM526_RS08435	COG0574	Belongs to the PEP-utilizing enzyme family
BM526_RS08435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM526_RS08470	COG2850	peptidyl-arginine hydroxylation
BM526_RS08480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BM526_RS08485	COG2915	High frequency lysogenization protein hflD homolog
BM526_RS08490	COG0482	sulfurtransferase activity
BM526_RS08495	COG1187	pseudouridine synthase activity
BM526_RS08505	COG1278	Cold shock
BM526_RS08510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BM526_RS08515	COG0542	response to heat
BM526_RS08520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BM526_RS08525	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BM526_RS08530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BM526_RS08535	COG0492	ferredoxin-NADP+ reductase activity
BM526_RS08545	COG3091	SprT-like family
BM526_RS08550	COG0616	signal peptide processing
BM526_RS08565	COG0778	Nitroreductase
BM526_RS08575	COG0252	asparaginase activity
BM526_RS08580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BM526_RS08585	COG0321	lipoyl(octanoyl) transferase activity
BM526_RS08590	COG2921	Belongs to the UPF0250 family
BM526_RS08595	COG1686	Belongs to the peptidase S11 family
BM526_RS08600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM526_RS08605	COG0772	Belongs to the SEDS family
BM526_RS08610	COG0768	penicillin binding
BM526_RS08615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BM526_RS08620	COG0799	negative regulation of ribosome biogenesis
BM526_RS08630	COG1466	dna polymerase III delta subunit
BM526_RS08635	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BM526_RS08640	COG0495	leucyl-tRNA aminoacylation
BM526_RS08650	COG1067	ATP-dependent peptidase activity
BM526_RS08655	COG0596	Alpha beta hydrolase
BM526_RS08660	COG3706	GGDEF domain
BM526_RS08670	COG1534	Rna-binding protein
BM526_RS08675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BM526_RS08680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM526_RS08685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BM526_RS08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM526_RS08695	COG0149	triose-phosphate isomerase activity
BM526_RS08700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM526_RS08710	COG3300	MHYT domain
BM526_RS08710	COG5001	Diguanylate cyclase
BM526_RS08730	COG1803	Methylglyoxal synthase
BM526_RS08730	COG1597	lipid kinase activity
BM526_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS08745	COG0561	phosphatase activity
BM526_RS08760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_RS08765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM526_RS08770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BM526_RS08785	COG1185	polyribonucleotide nucleotidyltransferase activity
BM526_RS08900	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BM526_RS08905	COG1196	nuclear chromosome segregation
BM526_RS08915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BM526_RS08930	COG1132	(ABC) transporter
BM526_RS08935	COG1663	tetraacyldisaccharide 4'-kinase activity
BM526_RS08975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BM526_RS08980	COG0435	Glutathione S-transferase
BM526_RS08985	COG1741	Belongs to the pirin family
BM526_RS08990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM526_RS09000	COG0372	Belongs to the citrate synthase family
BM526_RS09010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BM526_RS09015	COG1053	succinate dehydrogenase
BM526_RS09020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM526_RS09025	COG0567	Dehydrogenase, E1 component
BM526_RS09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_RS09085	COG4667	esterase of the alpha-beta hydrolase superfamily
BM526_RS09105	COG0366	Alpha amylase catalytic
BM526_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS09135	COG2267	carboxylic ester hydrolase activity
BM526_RS09145	COG0616	signal peptide processing
BM526_RS09165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_RS09170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM526_RS09175	COG0386	Belongs to the glutathione peroxidase family
BM526_RS09180	COG2084	Dehydrogenase
BM526_RS09190	COG1960	acyl-CoA dehydrogenase activity
BM526_RS09195	COG1024	Enoyl-CoA hydratase
BM526_RS09200	COG2226	methyltransferase
BM526_RS09205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM526_RS09210	COG3083	sulfuric ester hydrolase activity
BM526_RS09215	COG3082	Protein of unknown function (DUF1414)
BM526_RS09220	COG3081	Nucleoid-associated protein
BM526_RS09250	COG3275	phosphorelay sensor kinase activity
BM526_RS09255	COG3279	Response regulator of the LytR AlgR family
BM526_RS09260	COG0205	6-phosphofructokinase activity
BM526_RS09270	COG0789	Transcriptional regulator
BM526_RS09320	COG2205	protein histidine kinase activity
BM526_RS09320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_RS09330	COG1054	Belongs to the UPF0176 family
BM526_RS09340	COG0513	Belongs to the DEAD box helicase family
BM526_RS09350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BM526_RS09355	COG0583	DNA-binding transcription factor activity
BM526_RS09375	COG1760	l-serine dehydratase
BM526_RS09400	COG1322	Protein conserved in bacteria
BM526_RS09405	COG1404	Belongs to the peptidase S8 family
BM526_RS09410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BM526_RS09415	COG0022	dehydrogenase e1 component
BM526_RS09425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BM526_RS09430	COG0515	serine threonine protein kinase
BM526_RS09435	COG1946	Acyl-CoA thioesterase
BM526_RS09445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM526_RS09455	COG1956	GAF domain-containing protein
BM526_RS09470	COG0793	Belongs to the peptidase S41A family
BM526_RS09475	COG0733	neurotransmitter:sodium symporter activity
BM526_RS09480	COG1757	Na H antiporter
BM526_RS09485	COG0308	aminopeptidase N
BM526_RS09515	COG2902	Dehydrogenase
BM526_RS09520	COG0167	dihydroorotate dehydrogenase activity
BM526_RS09535	COG0488	(ABC) transporter
BM526_RS09545	COG3130	regulation of translation
BM526_RS09550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM526_RS09560	COG0415	Belongs to the DNA photolyase family
BM526_RS09565	COG0415	Belongs to the DNA photolyase family
BM526_RS09570	COG0415	Belongs to the DNA photolyase family
BM526_RS09575	COG3046	protein related to deoxyribodipyrimidine photolyase
BM526_RS09610	COG1082	Xylose isomerase domain protein TIM barrel
BM526_RS09635	COG4974	Belongs to the 'phage' integrase family
BM526_RS09645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BM526_RS09650	COG0589	response to stress
BM526_RS09660	COG0069	glutamate synthase activity
BM526_RS09675	COG2193	ferroxidase activity
BM526_RS09685	COG3278	Belongs to the heme-copper respiratory oxidase family
BM526_RS09700	COG2010	Cytochrome c
BM526_RS09710	COG2217	Heavy metal translocating P-type atpase
BM526_RS09725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM526_RS09730	COG0589	response to stress
BM526_RS09735	COG0037	tRNA processing
BM526_RS09740	COG1752	Esterase of the alpha-beta hydrolase superfamily
BM526_RS09760	COG1280	lysine exporter protein (LysE YggA)
BM526_RS09770	COG2897	thiosulfate sulfurtransferase activity
BM526_RS09775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BM526_RS09780	COG3148	PFAM DTW domain containing protein
BM526_RS09805	COG0322	excinuclease ABC activity
BM526_RS09810	COG2197	response regulator
BM526_RS09815	COG0436	Aminotransferase
BM526_RS09845	COG2259	Doxx family
BM526_RS09850	COG0583	DNA-binding transcription factor activity
BM526_RS09870	COG0670	Belongs to the BI1 family
BM526_RS09875	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BM526_RS09890	COG2920	part of a sulfur-relay system
BM526_RS09920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BM526_RS09930	COG0531	amino acid
BM526_RS09930	COG1674	ftsk spoiiie
BM526_RS09940	COG0686	Belongs to the AlaDH PNT family
BM526_RS09945	COG0284	orotidine-5'-phosphate decarboxylase activity
BM526_RS09950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BM526_RS09965	COG0776	regulation of translation
BM526_RS09970	COG0539	negative regulation of cytoplasmic translation
BM526_RS09975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BM526_RS09980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM526_RS09985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM526_RS09995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_RS10000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM526_RS10005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM526_RS10010	COG0633	Ferredoxin
BM526_RS10040	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM526_RS10045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM526_RS10055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM526_RS10065	COG4783	chaperone-mediated protein folding
BM526_RS10075	COG1393	Belongs to the ArsC family
BM526_RS10090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_RS10105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM526_RS10115	COG1960	acyl-CoA dehydrogenase activity
BM526_RS10140	COG0572	uridine kinase
BM526_RS10145	COG3769	mannosylglycerate metabolic process
BM526_RS10150	COG1215	transferase activity, transferring glycosyl groups
BM526_RS10155	COG0366	Alpha amylase catalytic
BM526_RS10165	COG0303	'Molybdopterin
BM526_RS10170	COG0534	Mate efflux family protein
BM526_RS10185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM526_RS10190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM526_RS10290	COG3547	Transposase (IS116 IS110 IS902 family)
BM526_RS10320	COG0405	Gamma-glutamyltransferase
BM526_RS10325	COG1024	Enoyl-CoA hydratase
BM526_RS10385	COG1671	Belongs to the UPF0178 family
BM526_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS10400	COG1960	acyl-CoA dehydrogenase activity
BM526_RS10405	COG2207	Transcriptional regulator
BM526_RS10405	COG0662	Cupin 2, conserved barrel domain protein
BM526_RS10410	COG4771	TonB-dependent receptor
BM526_RS10420	COG1505	serine-type exopeptidase activity
BM526_RS10430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS10460	COG0596	Alpha beta hydrolase
BM526_RS10470	COG0716	FMN binding
BM526_RS10480	COG0735	belongs to the Fur family
BM526_RS10490	COG1984	allophanate hydrolase subunit 2
BM526_RS10495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BM526_RS10500	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BM526_RS10505	COG2996	Protein conserved in bacteria
BM526_RS10510	COG1765	OsmC-like protein
BM526_RS10515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS10525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_RS10540	COG0436	Aminotransferase
BM526_RS10545	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM526_RS10550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BM526_RS10575	COG3012	SEC-C Motif Domain Protein
BM526_RS10580	COG5001	Diguanylate cyclase
BM526_RS10580	COG3447	MASE1 domain protein
BM526_RS10580	COG5002	protein histidine kinase activity
BM526_RS10585	COG0366	Alpha amylase catalytic
BM526_RS10595	COG0604	alcohol dehydrogenase
BM526_RS10605	COG1960	acyl-CoA dehydrogenase activity
BM526_RS10615	COG4771	TonB-dependent receptor
BM526_RS10635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM526_RS10640	COG1618	nucleotide phosphatase activity, acting on free nucleotides
BM526_RS10640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BM526_RS10660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BM526_RS10670	COG0521	Mo-molybdopterin cofactor biosynthetic process
BM526_RS10675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM526_RS10710	COG0436	Aminotransferase
BM526_RS10715	COG3268	Saccharopine dehydrogenase
BM526_RS10720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM526_RS10745	COG4206	TonB-dependent receptor
BM526_RS10755	COG5006	permease, DMT superfamily
BM526_RS10780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM526_RS10785	COG1074	ATP-dependent DNA helicase activity
BM526_RS10790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BM526_RS10805	COG1022	Amp-dependent synthetase and ligase
BM526_RS10810	COG2203	Gaf domain
BM526_RS10810	COG3706	GGDEF domain
BM526_RS10810	COG5001	Diguanylate cyclase
BM526_RS10810	COG4251	negative regulation of phosphorylation
BM526_RS10830	COG0583	DNA-binding transcription factor activity
BM526_RS10845	COG0640	Transcriptional regulator
BM526_RS10865	COG2204	response regulator
BM526_RS10875	COG4251	negative regulation of phosphorylation
BM526_RS10880	COG0784	Response regulator, receiver
BM526_RS10885	COG0784	Response regulator, receiver
BM526_RS10885	COG2205	protein histidine kinase activity
BM526_RS10910	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM526_RS10935	COG3139	Protein of unknown function (DUF1315)
BM526_RS10950	COG1115	amino acid carrier protein
BM526_RS10955	COG2866	Carboxypeptidase
BM526_RS10975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BM526_RS10985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BM526_RS10990	COG1640	4-alpha-glucanotransferase
BM526_RS10995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BM526_RS11000	COG0676	glucose-6-phosphate 1-epimerase activity
BM526_RS11005	COG0800	Aldolase
BM526_RS11015	COG0129	dihydroxy-acid dehydratase activity
BM526_RS11025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BM526_RS11030	COG1737	Transcriptional regulator
BM526_RS11035	COG0469	pyruvate kinase activity
BM526_RS11040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_RS11055	COG2823	Periplasmic or secreted lipoprotein
BM526_RS11085	COG3665	Urea carboxylase-associated protein
BM526_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS11110	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BM526_RS11120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BM526_RS11135	COG2721	sulfolactate sulfo-lyase activity
BM526_RS11140	COG1904	glucuronate isomerase
BM526_RS11145	COG0246	Mannitol dehydrogenase
BM526_RS11150	COG0800	Aldolase
BM526_RS11155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_RS11160	COG2755	lipolytic protein G-D-S-L family
BM526_RS11170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BM526_RS11195	COG2356	endonuclease I
BM526_RS11200	COG0840	transmembrane signaling receptor activity
BM526_RS11215	COG0583	DNA-binding transcription factor activity
BM526_RS11220	COG1979	alcohol dehydrogenase
BM526_RS11225	COG5001	Diguanylate cyclase
BM526_RS11235	COG0784	Response regulator, receiver
BM526_RS11235	COG3437	response regulator, receiver
BM526_RS11240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_RS11240	COG4191	Histidine kinase
BM526_RS11275	COG0471	metal ion transport
BM526_RS11285	COG0489	protein tyrosine kinase activity
BM526_RS11290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_RS11290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_RS11295	COG0668	transmembrane transport
BM526_RS11300	COG2226	methyltransferase
BM526_RS11305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_RS11310	COG1388	LysM domain
BM526_RS11310	COG0741	lytic transglycosylase activity
BM526_RS11335	COG0215	cysteine-tRNA ligase activity
BM526_RS11340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM526_RS11345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM526_RS11355	COG2268	Band 7 protein
BM526_RS11370	COG1733	regulation of RNA biosynthetic process
BM526_RS11375	COG0604	alcohol dehydrogenase
BM526_RS11380	COG0753	catalase activity
BM526_RS11385	COG0604	alcohol dehydrogenase
BM526_RS11390	COG0583	DNA-binding transcription factor activity
BM526_RS11415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BM526_RS11420	COG1286	toxin biosynthetic process
BM526_RS11425	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BM526_RS11430	COG0285	dihydrofolate synthase activity
BM526_RS11450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BM526_RS11455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM526_RS11475	COG3609	addiction module antidote protein, CC2985 family
BM526_RS11480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM526_RS11485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM526_RS11490	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_RS11500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BM526_RS11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM526_RS11535	COG0789	Transcriptional regulator
BM526_RS11540	COG0604	alcohol dehydrogenase
BM526_RS11555	COG1119	ATPase activity
BM526_RS11560	COG2031	fatty acid transporter
BM526_RS11565	COG5002	protein histidine kinase activity
BM526_RS11565	COG2205	protein histidine kinase activity
BM526_RS11565	COG0784	Response regulator, receiver
BM526_RS11575	COG0612	Peptidase, M16
BM526_RS11590	COG3101	peptidyl-lysine hydroxylation
BM526_RS11620	COG1902	pentaerythritol trinitrate reductase activity
BM526_RS11620	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM526_RS11645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM526_RS11655	COG4399	Belongs to the UPF0754 family
BM526_RS11680	COG1770	oligopeptidase
BM526_RS11685	COG2186	Transcriptional regulator
BM526_RS11695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BM526_RS11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM526_RS11710	COG2983	Belongs to the UPF0260 family
BM526_RS11715	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM526_RS11730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BM526_RS11735	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_RS11740	COG2267	carboxylic ester hydrolase activity
BM526_RS11755	COG1214	PFAM Peptidase M22, glycoprotease
BM526_RS11760	COG1199	ATP-dependent helicase activity
BM526_RS11820	COG4771	TonB-dependent receptor
BM526_RS11830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BM526_RS11835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BM526_RS11840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM526_RS11845	COG0131	Imidazoleglycerol-phosphate dehydratase
BM526_RS11845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM526_RS11850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BM526_RS11865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BM526_RS11865	COG0140	phosphoribosyl-ATP diphosphatase activity
BM526_RS11870	COG2116	formate transmembrane transporter activity
BM526_RS11905	COG0326	Molecular chaperone. Has ATPase activity
BM526_RS11910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BM526_RS11930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BM526_RS11935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BM526_RS11945	COG3220	belongs to the UPF0276 family
BM526_RS11955	COG0577	efflux transmembrane transporter activity
BM526_RS11955	COG1136	(ABC) transporter
BM526_RS11965	COG2203	Gaf domain
BM526_RS11965	COG5001	Diguanylate cyclase
BM526_RS11965	COG3706	GGDEF domain
BM526_RS11965	COG4251	negative regulation of phosphorylation
BM526_RS12000	COG1183	phosphatidylcholine synthase activity
BM526_RS12020	COG0277	FAD linked oxidase domain protein
BM526_RS12025	COG0542	response to heat
BM526_RS12030	COG1496	oxidoreductase activity
BM526_RS12050	COG1595	DNA-templated transcription, initiation
BM526_RS12065	COG4221	oxidoreductase activity
BM526_RS12080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BM526_RS12090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BM526_RS12100	COG0142	geranyltranstransferase activity
BM526_RS12110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BM526_RS12115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BM526_RS12125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BM526_RS12140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM526_RS12140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM526_RS12155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM526_RS12160	COG0488	(ABC) transporter
BM526_RS12170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BM526_RS12180	COG0560	Phosphoserine phosphatase
BM526_RS12190	COG0084	hydrolase, TatD family'
BM526_RS12200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BM526_RS12205	COG0571	ribonuclease III activity
BM526_RS12235	COG1595	DNA-templated transcription, initiation
BM526_RS12240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BM526_RS12255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BM526_RS12335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BM526_RS12340	COG1047	Peptidyl-prolyl cis-trans
BM526_RS12350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM526_RS12355	COG0196	riboflavin kinase activity
BM526_RS12360	COG0728	peptidoglycan biosynthetic process
BM526_RS12365	COG0268	Binds directly to 16S ribosomal RNA
BM526_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS12385	COG0385	Bile acid
BM526_RS12390	COG0583	DNA-binding transcription factor activity
BM526_RS12415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_RS12420	COG0776	regulation of translation
BM526_RS12425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM526_RS12430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BM526_RS12435	COG0740	serine-type endopeptidase activity
BM526_RS12440	COG0544	peptidyl-prolyl cis-trans isomerase activity
BM526_RS12495	COG1720	tRNA m6t6A37 methyltransferase activity
BM526_RS12505	COG1234	tRNA 3'-trailer cleavage
BM526_RS12515	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM526_RS12530	COG0517	IMP dehydrogenase activity
BM526_RS12530	COG0516	GMP reductase activity
BM526_RS12535	COG1570	exodeoxyribonuclease VII activity
BM526_RS12560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_RS12565	COG2976	Protein conserved in bacteria
BM526_RS12590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BM526_RS12600	COG2166	iron-sulfur cluster assembly
BM526_RS12615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM526_RS12620	COG0719	Fe-S assembly protein
BM526_RS12625	COG0396	ATPase activity
BM526_RS12630	COG0719	Fe-S assembly protein
BM526_RS12635	COG1104	cysteine desulfurase activity
BM526_RS12640	COG1959	2 iron, 2 sulfur cluster binding
BM526_RS12645	COG2072	flavoprotein involved in K transport
BM526_RS12655	COG1045	serine acetyltransferase
BM526_RS12660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BM526_RS12665	COG0483	inositol monophosphate 1-phosphatase activity
BM526_RS12680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_RS12685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_RS12690	COG1862	Preprotein translocase
BM526_RS12695	COG0343	queuine tRNA-ribosyltransferase activity
BM526_RS12715	COG1842	Phage shock protein A
BM526_RS12720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM526_RS12740	COG0754	glutathionylspermidine amidase activity
BM526_RS12770	COG2066	Belongs to the glutaminase family
BM526_RS12775	COG1785	Belongs to the alkaline phosphatase family
BM526_RS12780	COG0745	RESPONSE REGULATOR receiver
BM526_RS12865	COG1215	transferase activity, transferring glycosyl groups
BM526_RS12890	COG1215	transferase activity, transferring glycosyl groups
BM526_RS12895	COG0463	Glycosyl transferase, family 2
BM526_RS12910	COG1216	Glycosyl transferase, family 2
BM526_RS12915	COG0463	Glycosyl transferase, family 2
BM526_RS12915	COG1216	Glycosyl transferase, family 2
BM526_RS12925	COG0297	glycogen (starch) synthase activity
BM526_RS12940	COG0438	transferase activity, transferring glycosyl groups
BM526_RS12960	COG0297	glycogen (starch) synthase activity
BM526_RS12960	COG0438	transferase activity, transferring glycosyl groups
BM526_RS12980	COG0489	protein tyrosine kinase activity
BM526_RS13000	COG3409	Peptidoglycan-binding domain 1 protein
BM526_RS13000	COG3267	Type II secretory pathway component ExeA
BM526_RS13005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_RS13005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM526_RS13035	COG1560	Kdo2-lipid A biosynthetic process
BM526_RS13050	COG1960	acyl-CoA dehydrogenase activity
BM526_RS13065	COG5001	Diguanylate cyclase
BM526_RS13065	COG3300	MHYT domain
BM526_RS13070	COG1435	thymidine kinase activity
BM526_RS13080	COG1609	Transcriptional regulator
BM526_RS13085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BM526_RS13120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM526_RS13125	COG1024	Enoyl-CoA hydratase
BM526_RS13125	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_RS13140	COG1012	belongs to the aldehyde dehydrogenase family
BM526_RS13160	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BM526_RS13165	COG0789	Transcriptional regulator
BM526_RS13195	COG1960	acyl-CoA dehydrogenase activity
BM526_RS13220	COG0745	RESPONSE REGULATOR receiver
BM526_RS13225	COG2205	protein histidine kinase activity
BM526_RS13270	COG2080	2 iron, 2 sulfur cluster binding
BM526_RS13275	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BM526_RS13280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM526_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_RS13305	COG4221	oxidoreductase activity
BM526_RS13310	COG0693	protein deglycase activity
BM526_RS13315	COG1295	ribonuclease BN
BM526_RS13360	COG2814	Major facilitator Superfamily
BM526_RS13385	COG0514	ATP-dependent DNA helicase (RecQ)
BM526_RS13410	COG3706	GGDEF domain
BM526_RS13425	COG4251	negative regulation of phosphorylation
BM526_RS13430	COG2133	pyrroloquinoline quinone binding
BM526_RS13435	COG3609	addiction module antidote protein, CC2985 family
BM526_RS13450	COG5002	protein histidine kinase activity
BM526_RS13485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM526_RS13485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BM526_RS13500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM526_RS13505	COG2971	BadF BadG BcrA BcrD
BM526_RS13510	COG0583	DNA-binding transcription factor activity
BM526_RS13515	COG1620	l-lactate permease
BM526_RS13540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_RS13545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_RS13550	COG0006	proline dipeptidase activity
BM526_RS13565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_RS13580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BM526_RS13585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BM526_RS13590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM526_RS13610	COG3313	Fe-S protein
BM526_RS13645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_RS13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_RS13655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BM526_RS13670	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM526_RS13675	COG3577	Aspartyl protease
BM526_RS13680	COG0157	Belongs to the NadC ModD family
BM526_RS13690	COG1459	type II secretion system
BM526_RS13695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM526_RS13700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM526_RS13700	COG0237	dephospho-CoA kinase activity
BM526_RS13705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BM526_RS13710	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM526_RS13715	COG3608	succinylglutamate desuccinylase aspartoacylase
BM526_RS13720	COG0494	nUDIX hydrolase
BM526_RS13730	COG0739	heme binding
BM526_RS13735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BM526_RS13740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BM526_RS13745	COG0849	cell division
BM526_RS13750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BM526_RS13755	COG1181	Belongs to the D-alanine--D-alanine ligase family
BM526_RS13760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM526_RS13770	COG0772	Belongs to the SEDS family
BM526_RS13775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BM526_RS13785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BM526_RS13790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BM526_RS13795	COG0768	penicillin binding
BM526_RS13800	COG3116	cell division
BM526_RS13810	COG2001	Belongs to the MraZ family
BM526_RS13830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_RS13855	COG0678	peroxiredoxin activity
BM526_RS13855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM526_RS13880	COG2204	response regulator
BM526_RS13885	COG2205	protein histidine kinase activity
BM526_RS13885	COG0784	Response regulator, receiver
BM526_RS13900	COG2271	Major facilitator Superfamily
BM526_RS13925	COG0668	transmembrane transport
BM526_RS13930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BM526_RS13935	COG0189	ligase activity
BM526_RS13940	COG1678	Uncharacterized ACR, COG1678
BM526_RS13945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BM526_RS13970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BM526_RS13975	COG0762	integral membrane protein
BM526_RS13985	COG1902	pentaerythritol trinitrate reductase activity
BM526_RS13985	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM526_RS14000	COG0625	glutathione transferase activity
BM526_RS14010	COG1764	response to oxidative stress
BM526_RS14025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BM526_RS14030	COG1396	sequence-specific DNA binding
BM526_RS14035	COG2814	Major facilitator Superfamily
BM526_RS14040	COG0724	RNA recognition motif
BM526_RS14065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BM526_RS14070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BM526_RS14075	COG0083	homoserine kinase activity
BM526_RS14090	COG0583	DNA-binding transcription factor activity
BM526_RS14105	COG0640	Transcriptional regulator
BM526_RS14115	COG0431	NADPH-dependent FMN reductase
BM526_RS14120	COG0798	PFAM Bile acid sodium symporter
BM526_RS14125	COG2201	protein-glutamate methylesterase activity
BM526_RS14130	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BM526_RS14140	COG0642	Histidine kinase
BM526_RS14160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BM526_RS14190	COG1748	Saccharopine dehydrogenase
BM526_RS14205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BM526_RS14210	COG3107	peptidoglycan biosynthetic process
BM526_RS14230	COG2823	Periplasmic or secreted lipoprotein
BM526_RS14250	COG4585	Histidine kinase
BM526_RS14255	COG2197	response regulator
BM526_RS14270	COG4771	TonB-dependent receptor
BM526_RS14280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BM526_RS14285	COG0372	Belongs to the citrate synthase family
BM526_RS14290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BM526_RS14295	COG2828	Protein conserved in bacteria
BM526_RS14300	COG2203	Gaf domain
BM526_RS14300	COG2199	diguanylate cyclase activity
BM526_RS14320	COG5002	protein histidine kinase activity
BM526_RS14320	COG2198	Histidine kinase
BM526_RS14320	COG0784	Response regulator, receiver
BM526_RS14325	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM526_RS14330	COG0070	glutamate synthase
BM526_RS14330	COG0067	glutamate synthase
BM526_RS14330	COG0069	glutamate synthase activity
BM526_RS14335	COG0493	'glutamate synthase
BM526_RS14355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_RS14360	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BM526_RS14365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BM526_RS14370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_RS14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM526_RS14390	COG5507	3-demethylubiquinone-9 3-methyltransferase
BM526_RS14395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BM526_RS14400	COG4942	peptidase
BM526_RS14405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BM526_RS14410	COG0738	Major facilitator superfamily
BM526_RS14420	COG1902	pentaerythritol trinitrate reductase activity
BM526_RS14440	COG0625	glutathione transferase activity
BM526_RS14465	COG2894	cell division
BM526_RS14470	COG0850	regulation of cytokinetic process
BM526_RS14480	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BM526_RS14500	COG1981	membrane
BM526_RS14515	COG1914	H( )-stimulated, divalent metal cation uptake system
BM526_RS14530	COG1217	gtp-binding protein TYPA
BM526_RS14535	COG0174	glutamine synthetase
BM526_RS14545	COG3852	Histidine kinase
BM526_RS14550	COG2204	response regulator
BM526_RS14555	COG3437	response regulator, receiver
BM526_RS14595	COG3437	response regulator, receiver
BM526_RS14595	COG3850	Histidine kinase
BM526_RS14595	COG4999	Histidine kinase
BM526_RS14595	COG2205	protein histidine kinase activity
BM526_RS14600	COG0525	valine-tRNA ligase activity
BM526_RS14605	COG2927	DNA polymerase III (CHI subunit)
BM526_RS14610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM526_RS14615	COG0795	lipopolysaccharide-transporting ATPase activity
BM526_RS14620	COG0795	lipopolysaccharide-transporting ATPase activity
BM526_RS14695	COG3459	Glycosyltransferase 36 associated
BM526_RS14705	COG2199	diguanylate cyclase activity
BM526_RS14705	COG2203	Gaf domain
BM526_RS14735	COG0673	inositol 2-dehydrogenase activity
BM526_RS14740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_RS14740	COG0784	Response regulator, receiver
BM526_RS14740	COG2205	protein histidine kinase activity
BM526_RS14740	COG2198	Histidine kinase
BM526_RS14745	COG0628	permease
BM526_RS14760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BM526_RS14765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BM526_RS14770	COG4558	Periplasmic binding protein
BM526_RS14780	COG4206	TonB-dependent receptor
BM526_RS14790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BM526_RS14815	COG4447	cellulose binding
BM526_RS14825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BM526_RS14835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BM526_RS14845	COG0679	Auxin Efflux Carrier
BM526_RS14855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_RS14865	COG0395	ABC-type sugar transport system, permease component
BM526_RS14885	COG2267	carboxylic ester hydrolase activity
BM526_RS14915	COG1131	(ABC) transporter
BM526_RS14925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM526_RS14980	COG2205	protein histidine kinase activity
BM526_RS14990	COG3901	Regulator of nitric oxide reductase transcription
BM526_RS14990	COG0348	domain, Protein
BM526_RS15000	COG2197	response regulator
BM526_RS15035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_RS15040	COG0277	FAD linked oxidase domain protein
BM526_RS15050	COG1462	curli production assembly transport component CsgG
BM526_RS15080	COG2197	response regulator
BM526_RS15105	COG0513	Belongs to the DEAD box helicase family
BM526_RS15110	COG5001	Diguanylate cyclase
BM526_RS15115	COG0800	Aldolase
BM526_RS15120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_RS15135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BM526_RS15135	COG3264	Mechanosensitive ion channel
BM526_RS15175	COG0730	response to heat
BM526_RS15180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM526_RS15195	COG4191	Histidine kinase
BM526_RS15205	COG0417	DNA replication proofreading
BM526_RS15215	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_RS15265	COG1309	transcriptional regulator
BM526_RS15275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_RS15285	COG1573	uracil-dna glycosylase
BM526_RS15290	COG5001	Diguanylate cyclase
BM526_RS15290	COG3300	MHYT domain
BM526_RS15310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM526_RS15330	COG1983	PspC domain protein
BM526_RS15335	COG1842	Phage shock protein A
BM526_RS15345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_RS15350	COG0582	viral genome integration into host DNA
BM526_RS15430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM526_RS15435	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BM526_RS15515	COG1621	beta-fructofuranosidase activity
BM526_RS15535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM526_RS15545	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BM526_RS15550	COG0204	Acyl-transferase
BM526_RS15555	COG0204	Acyl-transferase
BM526_RS15560	COG0668	transmembrane transport
BM526_RS15575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM526_RS15580	COG0733	neurotransmitter:sodium symporter activity
BM526_RS15595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM526_RS15620	COG0848	biopolymer transport protein
BM526_RS15635	COG0457	Tetratricopeptide repeat
BM526_RS15640	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BM526_RS15650	COG1215	transferase activity, transferring glycosyl groups
BM526_RS15665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BM526_RS15685	COG5001	Diguanylate cyclase
BM526_RS15685	COG5002	protein histidine kinase activity
BM526_RS15695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BM526_RS15705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_RS15715	COG0583	DNA-binding transcription factor activity
BM526_RS15720	COG0121	glutamine amidotransferase
BM526_RS15730	COG4682	membrane
BM526_RS15750	COG1953	Uracil, thiamine, allantoin
BM526_RS15755	COG4771	TonB-dependent receptor
BM526_RS15765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM526_RS15775	COG0596	Alpha beta hydrolase
BM526_RS15780	COG0251	oxidation-reduction process
BM526_RS15785	COG1335	isochorismatase
BM526_RS15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_RS15795	COG1309	transcriptional regulator
BM526_RS15810	COG4628	conserved protein (DUF2132)
BM526_RS15815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_RS15825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BM526_RS15845	COG1477	protein flavinylation
BM526_RS15850	COG2871	sodium ion transport
BM526_RS15855	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_RS15860	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_RS15865	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_RS15870	COG1805	sodium ion transport
BM526_RS15875	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_RS15880	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BM526_RS15885	COG0545	Peptidyl-prolyl cis-trans isomerase
BM526_RS15890	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BM526_RS15905	COG0039	L-malate dehydrogenase activity
BM526_RS15910	COG1438	arginine binding
BM526_RS15935	COG0572	uridine kinase
BM526_RS15940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BM526_RS15955	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BM526_RS15970	COG2176	DNA-directed DNA polymerase activity
BM526_RS15980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_RS15990	COG2205	protein histidine kinase activity
BM526_RS16000	COG0189	ligase activity
BM526_RS16010	COG4067	protein conserved in archaea
BM526_RS16010	COG0189	ligase activity
BM526_RS16025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BM526_RS16035	COG1283	sodium-dependent phosphate transmembrane transporter activity
BM526_RS16040	COG0667	Aldo Keto reductase
BM526_RS16065	COG2815	serine threonine protein kinase
BM526_RS16065	COG0515	serine threonine protein kinase
BM526_RS16125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BM526_RS16145	COG2274	protein secretion by the type I secretion system
BM526_RS16150	COG0583	DNA-binding transcription factor activity
BM526_RS16185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM526_RS16200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM526_RS16250	COG2244	polysaccharide biosynthetic process
BM526_RS16270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BM526_RS16280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BM526_RS16285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BM526_RS16300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_RS16315	COG0202	RNA polymerase activity
BM526_RS16340	COG0201	protein transport
BM526_RS16360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BM526_RS16395	COG0784	Response regulator, receiver
BM526_RS16395	COG5002	protein histidine kinase activity
BM526_RS16410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM526_RS16415	COG0557	exoribonuclease II activity
BM526_RS16435	COG4771	TonB-dependent receptor
BM526_RS16460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BM526_RS16475	COG0543	2 iron, 2 sulfur cluster binding
BM526_RS16485	COG2234	aminopeptidase activity
BM526_RS16495	COG4251	negative regulation of phosphorylation
BM526_RS16505	COG1271	oxidase subunit
BM526_RS16510	COG1294	oxidase, subunit
BM526_RS16515	COG1522	sequence-specific DNA binding
BM526_RS16525	COG1278	Cold shock
BM526_RS16530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM526_RS16550	COG0339	signal peptide processing
BM526_RS16555	COG2201	protein-glutamate methylesterase activity
BM526_RS16565	COG3852	Histidine kinase
BM526_RS16575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_RS16580	COG0243	molybdopterin cofactor binding
BM526_RS16585	COG0823	Involved in the tonB-independent uptake of proteins
BM526_RS16585	COG1506	peptidase
BM526_RS16585	COG4946	Tricorn protease homolog
BM526_RS16630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_RS16640	COG2197	response regulator
BM526_RS16670	COG1621	beta-fructofuranosidase activity
BM526_RS16675	COG2814	Major facilitator Superfamily
BM526_RS16680	COG0702	epimerase
BM526_RS16685	COG4771	TonB-dependent receptor
BM526_RS16695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BM526_RS16700	COG1278	Cold shock
BM526_RS16710	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM526_RS16715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BM526_RS16730	COG0281	malic enzyme
BM526_RS16740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BM526_RS16770	COG0456	acetyltransferase
BM526_RS16780	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM526_RS16785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM526_RS16790	COG2177	Part of the ABC transporter FtsEX involved in
BM526_RS16795	COG2884	Cell division ATP-binding protein ftsE
BM526_RS16800	COG0552	protein localization to endoplasmic reticulum
BM526_RS16805	COG0742	ribosomal rna small subunit methyltransferase
BM526_RS16815	COG2095	MarC family integral membrane protein
BM526_RS16840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM526_RS16845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM526_RS16850	COG0617	tRNA 3'-terminal CCA addition
BM526_RS16855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM526_RS16870	COG0076	glutamate decarboxylase activity
BM526_RS16885	COG0842	Transport permease protein
BM526_RS16890	COG1131	(ABC) transporter
BM526_RS16895	COG0745	RESPONSE REGULATOR receiver
BM526_RS16900	COG2205	protein histidine kinase activity
BM526_RS16905	COG4774	siderophore transport
BM526_RS16930	COG1253	flavin adenine dinucleotide binding
BM526_RS16940	COG1966	Carbon starvation protein
BM526_RS16950	COG0657	acetylesterase activity
BM526_RS16970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BM526_RS17000	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BM526_RS17010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BM526_RS17045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BM526_RS17050	COG0049	tRNA binding
BM526_RS17055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BM526_RS17060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BM526_RS17065	COG0085	RNA polymerase activity
BM526_RS17070	COG0222	ribosome binding
BM526_RS17075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BM526_RS17080	COG0081	regulation of translation
BM526_RS17085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BM526_RS17105	COG0250	Participates in transcription elongation, termination and antitermination
BM526_RS17110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM526_RS17120	COG1132	(ABC) transporter
BM526_RS17125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BM526_RS17130	COG3590	peptidase
BM526_RS17140	COG0513	Belongs to the DEAD box helicase family
BM526_RS17145	COG0418	dihydroorotase activity
BM526_RS17150	COG3040	lipid binding
BM526_RS17155	COG4989	oxidoreductase activity
BM526_RS17160	COG0346	lactoylglutathione lyase activity
BM526_RS17165	COG0668	transmembrane transport
BM526_RS17185	COG0302	gtp cyclohydrolase
BM526_RS17195	COG2957	Belongs to the agmatine deiminase family
BM526_RS17200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_RS17210	COG1201	RNA secondary structure unwinding
BM526_RS17220	COG1793	dna ligase
BM526_RS17225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM526_RS17230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_RS17240	COG1410	methionine synthase
BM526_RS17240	COG0646	methionine synthase
BM526_RS17245	COG0625	glutathione transferase activity
BM526_RS17250	COG0625	glutathione transferase activity
BM526_RS17260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BM526_RS17275	COG1012	belongs to the aldehyde dehydrogenase family
BM526_RS17280	COG0028	Belongs to the TPP enzyme family
BM526_RS17290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BM526_RS17295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BM526_RS17300	COG0330	HflC and HflK could
BM526_RS17305	COG0330	HflC and HflK could
BM526_RS17310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BM526_RS17315	COG1923	regulation of RNA biosynthetic process
BM526_RS17320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BM526_RS17335	COG0802	atpase or kinase
BM526_RS17340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BM526_RS17340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BM526_RS17345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BM526_RS17365	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BM526_RS17370	COG0735	belongs to the Fur family
BM526_RS17390	COG0305	Participates in initiation and elongation during chromosome replication
BM526_RS17415	COG2258	MOSC domain
BM526_RS17475	COG2205	protein histidine kinase activity
BM526_RS17475	COG2198	Histidine kinase
BM526_RS17475	COG0784	Response regulator, receiver
BM526_RS17485	COG1136	(ABC) transporter
BM526_RS17485	COG0577	efflux transmembrane transporter activity
BM526_RS17495	COG0840	transmembrane signaling receptor activity
BM526_RS17500	COG5002	protein histidine kinase activity
BM526_RS17505	COG0840	transmembrane signaling receptor activity
BM526_RS17520	COG2855	membrane
BM526_RS17525	COG2175	clavaminate synthase activity
BM526_RS17530	COG0656	L-ascorbic acid biosynthetic process
BM526_RS17550	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_RS17555	COG4771	TonB-dependent receptor
BM526_RS17575	COG1757	Na H antiporter
BM526_RS17580	COG1472	Belongs to the glycosyl hydrolase 3 family
BM526_RS17590	COG2723	6-phospho-beta-galactosidase activity
BM526_RS17595	COG1609	Transcriptional regulator
BM526_RS17600	COG0477	Major facilitator Superfamily
BM526_RS17600	COG2814	Major facilitator Superfamily
BM526_RS17605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM526_RS17610	COG4988	ABC transporter
BM526_RS17615	COG4890	Cyd operon protein YbgT
BM526_RS17620	COG1294	oxidase, subunit
BM526_RS17655	COG4319	ketosteroid isomerase
BM526_RS17670	COG2375	cellular response to nickel ion
BM526_RS17675	COG3237	CsbD-like
BM526_RS17690	COG1595	DNA-templated transcription, initiation
BM526_RS17695	COG1404	Belongs to the peptidase S8 family
BM526_RS17720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_RS17720	COG0596	Alpha beta hydrolase
BM526_RS17740	COG3038	cytochrome b561
BM526_RS17750	COG1252	NADH dehydrogenase
BM526_RS17765	COG0583	DNA-binding transcription factor activity
BM526_RS17770	COG2067	long-chain fatty acid transport protein
BM526_RS17775	COG2130	NADP-dependent
BM526_RS17780	COG4251	negative regulation of phosphorylation
BM526_RS17780	COG3706	GGDEF domain
BM526_RS17780	COG2203	Gaf domain
BM526_RS17780	COG5001	Diguanylate cyclase
BM526_RS17785	COG0784	Response regulator, receiver
BM526_RS17785	COG2205	protein histidine kinase activity
BM526_RS17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_RS17800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM526_RS17805	COG1349	DNA-binding transcription factor activity
BM526_RS17810	COG0673	inositol 2-dehydrogenase activity
BM526_RS17825	COG0697	spore germination
BM526_RS17830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BM526_RS17835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BM526_RS17840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM526_RS17845	COG1166	arginine decarboxylase activity
BM526_RS17855	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BM526_RS17915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_RS17955	COG3030	protein affecting phage T7 exclusion by the F plasmid
BM526_RS17960	COG1324	tolerance protein
BM526_RS17965	COG4232	protein-disulfide reductase activity
BM526_RS17970	COG0739	heme binding
BM526_RS17975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM526_RS17980	COG0511	ligase activity, forming carbon-carbon bonds
BM526_RS17985	COG0439	Biotin carboxylase
BM526_RS18035	COG0154	amidase activity
BM526_RS18050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_RS18055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BM526_RS18070	COG0151	Belongs to the GarS family
BM526_RS18090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM526_RS18095	COG3954	Phosphoribulokinase
BM526_RS18120	COG1501	Belongs to the glycosyl hydrolase 31 family
BM526_RS18125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BM526_RS18135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BM526_RS18145	COG3031	protein transport across the cell outer membrane
BM526_RS18155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_RS18160	COG1459	type II secretion system
BM526_RS18165	COG2165	general secretion pathway protein
BM526_RS18170	COG2165	general secretion pathway protein
BM526_RS18175	COG2165	general secretion pathway protein
BM526_RS18180	COG4795	General secretion pathway protein
BM526_RS18195	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BM526_RS18215	COG1012	belongs to the aldehyde dehydrogenase family
BM526_RS18225	COG1011	Hydrolase
BM526_RS18230	COG0494	nUDIX hydrolase
BM526_RS18235	COG1218	3'(2'),5'-bisphosphate nucleotidase
BM526_RS18245	COG2943	transferase activity, transferring hexosyl groups
BM526_RS18250	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BM526_RS18260	COG3089	Belongs to the UPF0270 family
BM526_RS18265	COG0429	hydrolase of the alpha beta-hydrolase fold
BM526_RS18275	COG0488	(ABC) transporter
BM526_RS18300	COG0545	Peptidyl-prolyl cis-trans isomerase
BM526_RS18310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM526_RS18315	COG2183	response to ionizing radiation
BM526_RS18335	COG0596	Alpha beta hydrolase
BM526_RS18340	COG1040	competence protein
BM526_RS18360	COG1794	racemase activity, acting on amino acids and derivatives
BM526_RS18375	COG0534	Mate efflux family protein
BM526_RS18380	COG0726	polysaccharide deacetylase
BM526_RS18380	COG1649	PFAM Uncharacterised BCR, COG1649
BM526_RS18390	COG1999	signal sequence binding
BM526_RS18395	COG0109	protoheme IX farnesyltransferase activity
BM526_RS18400	COG1612	heme a metabolic process
BM526_RS18420	COG1845	cytochrome c oxidase, subunit III
BM526_RS18425	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BM526_RS18430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BM526_RS18435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BM526_RS18455	COG0129	dihydroxy-acid dehydratase activity
BM526_RS18465	COG0606	chelatase, subunit chli
BM526_RS18470	COG0583	DNA-binding transcription factor activity
BM526_RS18480	COG2814	Major facilitator Superfamily
BM526_RS18485	COG1073	alpha beta
BM526_RS18490	COG0729	surface antigen
BM526_RS18495	COG2911	Protein conserved in bacteria
BM526_RS18520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM526_RS18530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM526_RS18550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM526_RS18575	COG1228	amidohydrolase
BM526_RS18600	COG0425	Belongs to the sulfur carrier protein TusA family
BM526_RS18615	COG1561	YicC-like family, N-terminal region
BM526_RS18635	COG2723	6-phospho-beta-galactosidase activity
BM526_RS18640	COG2211	Major facilitator Superfamily
BM526_RS18645	COG1609	Transcriptional regulator
BM526_RS18660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BM526_RS18660	COG2199	diguanylate cyclase activity
BM526_RS18685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BM526_RS18705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BM526_RS18710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BM526_RS18730	COG1475	DNA binding
BM526_RS18735	COG1192	Involved in chromosome partitioning
BM526_RS18760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM526_RS18765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BM526_RS18775	COG0706	membrane insertase activity
BM526_RS18780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BM526_RS18785	COG0594	ribonuclease P activity
BM526_RS18790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BM526_RS18805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_RS18810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_RS19260	COG0210	DNA helicase
BM526_RS19330	COG3453	Protein conserved in bacteria
BM526_RS19330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_RS19540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM526_RS19575	COG1960	acyl-CoA dehydrogenase activity
BM526_RS19705	COG4771	TonB-dependent receptor
BM526_RS19830	COG2959	enzyme of heme biosynthesis
BM526_RS19875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM526_RS20010	COG0427	acetyl-CoA hydrolase
BM526_RS20505	COG0312	modulator of DNA gyrase
BM526_RS20515	COG0312	modulator of DNA gyrase
BM526_RS20540	COG0312	modulator of DNA gyrase