locus-tag	class	description
AV941_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV941_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV941_RS00040	COG2818	Glycosylase
AV941_RS00050	COG3078	GTPase activator activity
AV941_RS00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV941_RS00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV941_RS00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AV941_RS00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV941_RS00085	COG0569	domain protein
AV941_RS00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV941_RS00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV941_RS00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV941_RS00110	COG0758	DNA mediated transformation
AV941_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
AV941_RS00130	COG0408	coproporphyrinogen oxidase activity
AV941_RS00135	COG3047	cAMP biosynthetic process
AV941_RS00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AV941_RS00225	COG2234	aminopeptidase activity
AV941_RS00230	COG0463	Glycosyl transferase, family 2
AV941_RS00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV941_RS00265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_RS00295	COG3642	lipopolysaccharide core region biosynthetic process
AV941_RS00300	COG0859	PFAM glycosyl transferase family 9
AV941_RS00330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_RS00345	COG3161	chorismate lyase activity
AV941_RS00350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AV941_RS00370	COG0210	DNA helicase
AV941_RS00400	COG1757	Na H antiporter
AV941_RS00415	COG1959	2 iron, 2 sulfur cluster binding
AV941_RS00420	COG0730	response to heat
AV941_RS00435	COG4771	TonB-dependent receptor
AV941_RS00450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV941_RS00455	COG4988	ABC transporter
AV941_RS00465	COG1271	oxidase subunit
AV941_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_RS00475	COG0425	Belongs to the sulfur carrier protein TusA family
AV941_RS00485	COG0450	alkyl hydroperoxide reductase
AV941_RS00495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV941_RS00525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_RS00570	COG0270	DNA (cytosine-5-)-methyltransferase activity
AV941_RS00575	COG0556	nucleotide-excision repair
AV941_RS00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS00590	COG1129	ABC transporter
AV941_RS00590	COG0842	Transport permease protein
AV941_RS00595	COG0842	Transport permease protein
AV941_RS00610	COG1960	acyl-CoA dehydrogenase activity
AV941_RS00615	COG0583	DNA-binding transcription factor activity
AV941_RS00625	COG3106	COG3106 Predicted ATPase
AV941_RS00640	COG2184	nucleotidyltransferase activity
AV941_RS00645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV941_RS00660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV941_RS00665	COG0352	thiamine-phosphate diphosphorylase activity
AV941_RS00675	COG3071	HemY protein
AV941_RS00680	COG2959	enzyme of heme biosynthesis
AV941_RS00690	COG0181	hydroxymethylbilane synthase activity
AV941_RS00705	COG0194	GDP metabolic process
AV941_RS00715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV941_RS00725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV941_RS00730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV941_RS00740	COG0678	peroxiredoxin activity
AV941_RS00755	COG1178	ABC-type Fe3 transport system permease component
AV941_RS00760	COG3842	ATPase activity
AV941_RS00765	COG0668	transmembrane transport
AV941_RS00770	COG2081	HI0933 family
AV941_RS00815	COG0789	Transcriptional regulator
AV941_RS00820	COG2963	transposase activity
AV941_RS00825	COG2801	Transposase and inactivated derivatives
AV941_RS00840	COG2200	EAL domain
AV941_RS00845	COG0583	DNA-binding transcription factor activity
AV941_RS00870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS00885	COG0427	acetyl-CoA hydrolase
AV941_RS00890	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV941_RS00905	COG0840	transmembrane signaling receptor activity
AV941_RS00915	COG3064	Membrane
AV941_RS00925	COG5002	protein histidine kinase activity
AV941_RS00925	COG5001	Diguanylate cyclase
AV941_RS00940	COG0514	ATP-dependent DNA helicase (RecQ)
AV941_RS00945	COG2239	Acts as a magnesium transporter
AV941_RS00950	COG2962	Rard protein
AV941_RS00960	COG0210	DNA helicase
AV941_RS00970	COG1011	Hydrolase
AV941_RS00975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AV941_RS00985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV941_RS00990	COG0019	diaminopimelate decarboxylase activity
AV941_RS01020	COG0163	prenyltransferase activity
AV941_RS01025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV941_RS01035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AV941_RS01055	COG1077	Cell shape determining protein MreB Mrl
AV941_RS01065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV941_RS01070	COG2814	Major facilitator Superfamily
AV941_RS01075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_RS01100	COG1085	galactose-1-phosphate uridylyltransferase
AV941_RS01105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AV941_RS01115	COG0629	single-stranded DNA binding
AV941_RS01130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV941_RS01135	COG3250	beta-galactosidase activity
AV941_RS01150	COG1349	DNA-binding transcription factor activity
AV941_RS01195	COG3409	Peptidoglycan-binding domain 1 protein
AV941_RS01195	COG3267	Type II secretory pathway component ExeA
AV941_RS01205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_RS01210	COG1459	type II secretion system
AV941_RS01220	COG2165	general secretion pathway protein
AV941_RS01225	COG2165	general secretion pathway protein
AV941_RS01255	COG1077	Cell shape determining protein MreB Mrl
AV941_RS01260	COG1792	Involved in formation and maintenance of cell shape
AV941_RS01265	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AV941_RS01275	COG1530	ribonuclease E activity
AV941_RS01285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_RS01290	COG0312	modulator of DNA gyrase
AV941_RS01295	COG3028	Belongs to the UPF0307 family
AV941_RS01300	COG0312	modulator of DNA gyrase
AV941_RS01315	COG0745	RESPONSE REGULATOR receiver
AV941_RS01320	COG4191	Histidine kinase
AV941_RS01320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_RS01325	COG0297	glycogen (starch) synthase activity
AV941_RS01335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV941_RS01340	COG0596	Alpha beta hydrolase
AV941_RS01370	COG5002	protein histidine kinase activity
AV941_RS01375	COG0745	RESPONSE REGULATOR receiver
AV941_RS01395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_RS01460	COG1017	nitric oxide dioxygenase activity
AV941_RS01460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV941_RS01480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AV941_RS01510	COG0375	protein maturation
AV941_RS01520	COG0409	Hydrogenase expression formation protein
AV941_RS01530	COG0309	Hydrogenase expression formation protein (HypE)
AV941_RS01535	COG0789	Transcriptional regulator
AV941_RS01540	COG2217	Heavy metal translocating P-type atpase
AV941_RS01625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV941_RS01635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV941_RS01645	COG0463	Glycosyl transferase, family 2
AV941_RS01650	COG0745	RESPONSE REGULATOR receiver
AV941_RS01655	COG5002	protein histidine kinase activity
AV941_RS01665	COG0789	Transcriptional regulator
AV941_RS01670	COG2217	Heavy metal translocating P-type atpase
AV941_RS01710	COG0531	amino acid
AV941_RS01755	COG2801	Transposase and inactivated derivatives
AV941_RS01840	COG1609	Transcriptional regulator
AV941_RS01845	COG0673	inositol 2-dehydrogenase activity
AV941_RS01855	COG2211	Major facilitator Superfamily
AV941_RS01880	COG1454	alcohol dehydrogenase
AV941_RS01930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_RS01950	COG0089	rRNA binding
AV941_RS01960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV941_RS01970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV941_RS01985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV941_RS01990	COG0438	transferase activity, transferring glycosyl groups
AV941_RS02000	COG1519	Transferase
AV941_RS02035	COG0788	formyltetrahydrofolate deformylase activity
AV941_RS02045	COG1643	Atp-dependent helicase
AV941_RS02050	COG2951	lytic endotransglycosylase activity
AV941_RS02055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV941_RS02065	COG2354	Protein conserved in bacteria
AV941_RS02085	COG0004	ammonium transporteR
AV941_RS02090	COG0405	Gamma-glutamyltransferase
AV941_RS02095	COG2837	iron assimilation
AV941_RS02110	COG0540	Belongs to the ATCase OTCase family
AV941_RS02135	COG2205	protein histidine kinase activity
AV941_RS02135	COG0784	Response regulator, receiver
AV941_RS02135	COG5002	protein histidine kinase activity
AV941_RS02150	COG5001	Diguanylate cyclase
AV941_RS02150	COG3300	MHYT domain
AV941_RS02160	COG1012	belongs to the aldehyde dehydrogenase family
AV941_RS02170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV941_RS02185	COG0180	Tryptophanyl-tRNA synthetase
AV941_RS02190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV941_RS02210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AV941_RS02220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV941_RS02255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AV941_RS02260	COG0281	malic enzyme
AV941_RS02270	COG0625	glutathione transferase activity
AV941_RS02280	COG0753	catalase activity
AV941_RS02295	COG5001	Diguanylate cyclase
AV941_RS02295	COG3300	MHYT domain
AV941_RS02300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV941_RS02300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV941_RS02310	COG0137	argininosuccinate synthase activity
AV941_RS02330	COG1803	Methylglyoxal synthase
AV941_RS02340	COG0745	RESPONSE REGULATOR receiver
AV941_RS02345	COG2205	protein histidine kinase activity
AV941_RS02350	COG2267	carboxylic ester hydrolase activity
AV941_RS02355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AV941_RS02365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AV941_RS02375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV941_RS02380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_RS02385	COG4942	peptidase
AV941_RS02390	COG2861	carbohydrate metabolic process
AV941_RS02415	COG1162	GTPase activity
AV941_RS02420	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV941_RS02455	COG0028	Belongs to the TPP enzyme family
AV941_RS02475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV941_RS02480	COG0805	protein transport
AV941_RS02490	COG0084	hydrolase, TatD family'
AV941_RS02495	COG4251	negative regulation of phosphorylation
AV941_RS02495	COG3706	GGDEF domain
AV941_RS02495	COG2203	Gaf domain
AV941_RS02495	COG5001	Diguanylate cyclase
AV941_RS02505	COG0248	Ppx GppA phosphatase
AV941_RS02510	COG0513	Belongs to the DEAD box helicase family
AV941_RS02515	COG3118	belongs to the thioredoxin family
AV941_RS02520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV941_RS02525	COG1473	amidohydrolase
AV941_RS02530	COG5002	protein histidine kinase activity
AV941_RS02530	COG0784	Response regulator, receiver
AV941_RS02535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AV941_RS02540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AV941_RS02545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV941_RS02560	COG0783	Belongs to the Dps family
AV941_RS02565	COG2133	pyrroloquinoline quinone binding
AV941_RS02570	COG1506	peptidase
AV941_RS02570	COG0823	Involved in the tonB-independent uptake of proteins
AV941_RS02570	COG4946	Tricorn protease homolog
AV941_RS02580	COG3118	belongs to the thioredoxin family
AV941_RS02595	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AV941_RS02605	COG1012	belongs to the aldehyde dehydrogenase family
AV941_RS02625	COG1757	Na H antiporter
AV941_RS02640	COG3876	Protein conserved in bacteria
AV941_RS02645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AV941_RS02655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV941_RS02665	COG0346	lactoylglutathione lyase activity
AV941_RS02690	COG2824	Alkylphosphonate utilization operon protein PhnA
AV941_RS02695	COG0454	-acetyltransferase
AV941_RS02725	COG3093	addiction module antidote protein HigA
AV941_RS02740	COG2026	Addiction module toxin, RelE StbE family
AV941_RS02840	COG3547	Transposase (IS116 IS110 IS902 family)
AV941_RS02895	COG0183	Belongs to the thiolase family
AV941_RS02900	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_RS02900	COG1024	Enoyl-CoA hydratase
AV941_RS02910	COG0006	proline dipeptidase activity
AV941_RS02920	COG0142	geranyltranstransferase activity
AV941_RS02950	COG4942	peptidase
AV941_RS02950	COG1388	LysM domain
AV941_RS02955	COG1238	metal cluster binding
AV941_RS02965	COG0585	pseudouridine synthase activity
AV941_RS02970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AV941_RS02980	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV941_RS02990	COG0840	transmembrane signaling receptor activity
AV941_RS03020	COG0494	nUDIX hydrolase
AV941_RS03025	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AV941_RS03030	COG0730	response to heat
AV941_RS03035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV941_RS03040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV941_RS03075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AV941_RS03085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV941_RS03095	COG1648	precorrin-2 dehydrogenase activity
AV941_RS03095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV941_RS03100	COG0513	Belongs to the DEAD box helicase family
AV941_RS03120	COG1538	Outer membrane efflux protein
AV941_RS03125	COG0494	nUDIX hydrolase
AV941_RS03135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV941_RS03140	COG3150	esterase
AV941_RS03145	COG0187	DNA topoisomerase II activity
AV941_RS03155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_RS03175	COG1509	lysine 2,3-aminomutase activity
AV941_RS03180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV941_RS03185	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AV941_RS03200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV941_RS03215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV941_RS03230	COG0271	Belongs to the BolA IbaG family
AV941_RS03245	COG3707	response regulator
AV941_RS03255	COG0659	secondary active sulfate transmembrane transporter activity
AV941_RS03260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AV941_RS03270	COG0243	molybdopterin cofactor binding
AV941_RS03275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV941_RS03275	COG1648	precorrin-2 dehydrogenase activity
AV941_RS03280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV941_RS03290	COG1116	anion transmembrane transporter activity
AV941_RS03290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV941_RS03300	COG1116	anion transmembrane transporter activity
AV941_RS03315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_RS03320	COG4206	TonB-dependent receptor
AV941_RS03330	COG0348	domain, Protein
AV941_RS03345	COG1960	acyl-CoA dehydrogenase activity
AV941_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS03360	COG4948	Mandelate Racemase Muconate Lactonizing
AV941_RS03375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS03380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_RS03405	COG0358	DNA primase activity
AV941_RS03430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV941_RS03435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV941_RS03450	COG0537	adenosine 5'-monophosphoramidase activity
AV941_RS03465	COG3135	benzoate transporter
AV941_RS03470	COG1396	sequence-specific DNA binding
AV941_RS03475	COG2974	May be involved in recombination
AV941_RS03480	COG4191	Histidine kinase
AV941_RS03480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_RS03485	COG0745	RESPONSE REGULATOR receiver
AV941_RS03490	COG5002	protein histidine kinase activity
AV941_RS03515	COG0811	peptide transport
AV941_RS03520	COG0811	peptide transport
AV941_RS03525	COG0848	biopolymer transport protein
AV941_RS03530	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AV941_RS03540	COG3437	response regulator, receiver
AV941_RS03560	COG2133	pyrroloquinoline quinone binding
AV941_RS03570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_RS03595	COG0527	aspartate kinase activity
AV941_RS03600	COG0840	transmembrane signaling receptor activity
AV941_RS03605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV941_RS03610	COG2967	ApaG domain
AV941_RS03620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV941_RS03625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_RS03630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV941_RS03635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV941_RS03645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_RS03665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV941_RS03680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV941_RS03685	COG3956	TIGRFAM MazG family protein
AV941_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS03720	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_RS03730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV941_RS03740	COG0463	Glycosyl transferase, family 2
AV941_RS03760	COG0642	Histidine kinase
AV941_RS03780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV941_RS03785	COG0723	plastoquinol--plastocyanin reductase activity
AV941_RS03790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV941_RS03795	COG2857	Cytochrome c1
AV941_RS03800	COG0625	glutathione transferase activity
AV941_RS03805	COG2969	positive regulation of protein catabolic process
AV941_RS03810	COG2239	Acts as a magnesium transporter
AV941_RS03815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV941_RS03835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV941_RS03840	COG1137	ATPase activity
AV941_RS03845	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AV941_RS03855	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV941_RS03870	COG1127	ABC transporter
AV941_RS03875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV941_RS03880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV941_RS03885	COG2854	intermembrane phospholipid transfer
AV941_RS03895	COG5007	Belongs to the BolA IbaG family
AV941_RS03905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV941_RS03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV941_RS03920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV941_RS03960	COG4771	TonB-dependent receptor
AV941_RS03965	COG0697	spore germination
AV941_RS03975	COG0784	Response regulator, receiver
AV941_RS03975	COG2205	protein histidine kinase activity
AV941_RS04000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV941_RS04010	COG0126	phosphoglycerate kinase activity
AV941_RS04015	COG3588	fructose-bisphosphate aldolase
AV941_RS04025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS04035	COG1538	Outer membrane efflux protein
AV941_RS04040	COG0823	Involved in the tonB-independent uptake of proteins
AV941_RS04040	COG1506	peptidase
AV941_RS04040	COG4946	Tricorn protease homolog
AV941_RS04045	COG0248	Ppx GppA phosphatase
AV941_RS04050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AV941_RS04060	COG0573	inorganic phosphate transmembrane transporter activity
AV941_RS04070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV941_RS04080	COG0306	phosphate transporter
AV941_RS04090	COG0583	DNA-binding transcription factor activity
AV941_RS04100	COG1272	protein, Hemolysin III
AV941_RS04105	COG1846	Transcriptional regulator
AV941_RS04110	COG1764	response to oxidative stress
AV941_RS04125	COG1739	Uncharacterized protein family UPF0029
AV941_RS04145	COG0420	3'-5' exonuclease activity
AV941_RS04150	COG0419	ATPase involved in DNA repair
AV941_RS04160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AV941_RS04175	COG2188	Transcriptional regulator
AV941_RS04180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AV941_RS04185	COG2986	histidine ammonia-lyase
AV941_RS04210	COG0488	(ABC) transporter
AV941_RS04230	COG0668	transmembrane transport
AV941_RS04290	COG1484	DNA-dependent DNA replication
AV941_RS04310	COG0582	viral genome integration into host DNA
AV941_RS04315	COG4372	Transposase
AV941_RS04360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV941_RS04375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AV941_RS04425	COG1346	cytolysis
AV941_RS04455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV941_RS04465	COG0513	Belongs to the DEAD box helicase family
AV941_RS04475	COG3409	Peptidoglycan-binding domain 1 protein
AV941_RS04475	COG3267	Type II secretory pathway component ExeA
AV941_RS04490	COG0066	3-isopropylmalate dehydratase activity
AV941_RS04500	COG0473	3-isopropylmalate dehydrogenase activity
AV941_RS04505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV941_RS04525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV941_RS04540	COG4555	ABC transporter
AV941_RS04545	COG1668	transmembrane transport
AV941_RS04560	COG4133	protoheme IX ABC transporter activity
AV941_RS04565	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_RS04570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_RS04575	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_RS04585	COG1138	Cytochrome C-type biogenesis protein
AV941_RS04590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV941_RS04605	COG2853	Lipoprotein
AV941_RS04610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV941_RS04650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV941_RS04665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AV941_RS04670	COG1596	polysaccharide export
AV941_RS04670	COG1555	photosystem II stabilization
AV941_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
AV941_RS04690	COG1611	Belongs to the LOG family
AV941_RS04700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV941_RS04700	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV941_RS04755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV941_RS04760	COG0024	Methionine aminopeptidase
AV941_RS04765	COG0052	Belongs to the universal ribosomal protein uS2 family
AV941_RS04775	COG0528	UMP kinase activity
AV941_RS04790	COG0575	Belongs to the CDS family
AV941_RS04815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV941_RS04820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV941_RS04835	COG0587	DNA-directed DNA polymerase activity
AV941_RS04840	COG0825	malonyl-CoA metabolic process
AV941_RS04845	COG0037	tRNA processing
AV941_RS04880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV941_RS04880	COG0047	phosphoribosylformylglycinamidine synthase activity
AV941_RS04890	COG2840	Smr protein MutS2
AV941_RS04920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS04925	COG2197	response regulator
AV941_RS04960	COG0835	chemotaxis
AV941_RS04960	COG0784	Response regulator, receiver
AV941_RS04965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AV941_RS04970	COG1815	bacterial-type flagellum-dependent cell motility
AV941_RS04990	COG4787	bacterial-type flagellum-dependent cell motility
AV941_RS05010	COG3951	Flagellar rod assembly protein muramidase FlgJ
AV941_RS05010	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV941_RS05015	COG1256	bacterial-type flagellum assembly
AV941_RS05030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV941_RS05035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV941_RS05050	COG1516	flagellar protein fliS
AV941_RS05065	COG1086	Polysaccharide biosynthesis protein
AV941_RS05070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV941_RS05080	COG2089	acid synthase
AV941_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS05145	COG1660	Displays ATPase and GTPase activities
AV941_RS05150	COG1216	Glycosyl transferase, family 2
AV941_RS05165	COG1083	cytidylyl-transferase
AV941_RS05190	COG1677	Flagellar hook-basal body complex protein FliE
AV941_RS05195	COG1766	The M ring may be actively involved in energy transduction
AV941_RS05200	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV941_RS05250	COG1987	bacterial-type flagellum assembly
AV941_RS05265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV941_RS05290	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV941_RS05295	COG0643	Histidine kinase
AV941_RS05295	COG2198	Histidine kinase
AV941_RS05295	COG0784	Response regulator, receiver
AV941_RS05305	COG1192	Involved in chromosome partitioning
AV941_RS05315	COG0835	chemotaxis
AV941_RS05330	COG0646	methionine synthase
AV941_RS05330	COG1410	methionine synthase
AV941_RS05335	COG0646	methionine synthase
AV941_RS05335	COG1410	methionine synthase
AV941_RS05345	COG3123	guanosine phosphorylase activity
AV941_RS05350	COG0583	DNA-binding transcription factor activity
AV941_RS05355	COG0583	DNA-binding transcription factor activity
AV941_RS05365	COG0659	secondary active sulfate transmembrane transporter activity
AV941_RS05380	COG3590	peptidase
AV941_RS05390	COG2137	regulation of response to DNA damage stimulus
AV941_RS05395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AV941_RS05425	COG5016	pyruvate
AV941_RS05425	COG0511	ligase activity, forming carbon-carbon bonds
AV941_RS05430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AV941_RS05435	COG4172	Belongs to the ABC transporter superfamily
AV941_RS05445	COG4171	peptide transport system, permease
AV941_RS05450	COG4168	peptide transport system, permease
AV941_RS05455	COG0747	negative chemotaxis
AV941_RS05460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AV941_RS05465	COG1842	Phage shock protein A
AV941_RS05495	COG0625	glutathione transferase activity
AV941_RS05500	COG1522	sequence-specific DNA binding
AV941_RS05565	COG0811	peptide transport
AV941_RS05570	COG0811	peptide transport
AV941_RS05575	COG0848	biopolymer transport protein
AV941_RS05590	COG1444	tRNA N-acetyltransferase activity
AV941_RS05630	COG0456	acetyltransferase
AV941_RS05645	COG0583	DNA-binding transcription factor activity
AV941_RS05650	COG2814	Major facilitator Superfamily
AV941_RS05655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_RS05660	COG0656	L-ascorbic acid biosynthetic process
AV941_RS05680	COG1846	Transcriptional regulator
AV941_RS05690	COG3620	sequence-specific DNA binding
AV941_RS05695	COG3550	peptidyl-serine autophosphorylation
AV941_RS05730	COG0668	transmembrane transport
AV941_RS05740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AV941_RS05760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV941_RS05855	COG0789	Transcriptional regulator
AV941_RS05865	COG0789	Transcriptional regulator
AV941_RS05875	COG0640	Transcriptional regulator
AV941_RS05885	COG1230	cation diffusion facilitator family transporter
AV941_RS05940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_RS05960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_RS05975	COG0681	Belongs to the peptidase S26 family
AV941_RS05995	COG1074	ATP-dependent DNA helicase activity
AV941_RS06005	COG1404	Belongs to the peptidase S8 family
AV941_RS06010	COG0464	growth
AV941_RS06030	COG0629	single-stranded DNA binding
AV941_RS06050	COG0714	Associated with various cellular activities
AV941_RS06075	COG2003	Belongs to the UPF0758 family
AV941_RS06095	COG0583	DNA-binding transcription factor activity
AV941_RS06185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV941_RS06235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV941_RS06240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV941_RS06245	COG0564	pseudouridine synthase activity
AV941_RS06255	COG0612	Peptidase, M16
AV941_RS06260	COG2918	glutathione biosynthetic process
AV941_RS06280	COG2840	Smr protein MutS2
AV941_RS06285	COG2890	protein-(glutamine-N5) methyltransferase activity
AV941_RS06300	COG2719	SpoVR family
AV941_RS06305	COG2718	Belongs to the UPF0229 family
AV941_RS06310	COG2766	serine protein kinase
AV941_RS06315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AV941_RS06320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV941_RS06325	COG4771	TonB-dependent receptor
AV941_RS06350	COG0450	alkyl hydroperoxide reductase
AV941_RS06355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV941_RS06360	COG2885	chlorophyll binding
AV941_RS06365	COG0584	glycerophosphoryl diester phosphodiesterase
AV941_RS06370	COG0346	lactoylglutathione lyase activity
AV941_RS06375	COG1278	Cold shock
AV941_RS06390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV941_RS06395	COG4660	Part of a membrane complex involved in electron transport
AV941_RS06400	COG4659	FMN binding
AV941_RS06405	COG4658	electron transport chain
AV941_RS06410	COG4656	Part of a membrane complex involved in electron transport
AV941_RS06415	COG2878	Part of a membrane complex involved in electron transport
AV941_RS06420	COG4657	Part of a membrane complex involved in electron transport
AV941_RS06435	COG0534	Mate efflux family protein
AV941_RS06440	COG0556	nucleotide-excision repair
AV941_RS06455	COG0602	queuosine metabolic process
AV941_RS06465	COG0367	asparagine synthase
AV941_RS06490	COG0471	metal ion transport
AV941_RS06490	COG3273	potassium ion transport
AV941_RS06505	COG0529	Catalyzes the synthesis of activated sulfate
AV941_RS06510	COG0175	sulfate reduction
AV941_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_RS06520	COG3706	GGDEF domain
AV941_RS06545	COG2304	oxidoreductase activity
AV941_RS06565	COG0714	Associated with various cellular activities
AV941_RS06575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_RS06575	COG1024	Enoyl-CoA hydratase
AV941_RS06595	COG1025	Belongs to the peptidase M16 family
AV941_RS06600	COG2062	phosphohistidine phosphatase, SixA
AV941_RS06610	COG4536	flavin adenine dinucleotide binding
AV941_RS06615	COG4137	Cytochrome C assembly protein
AV941_RS06620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV941_RS06665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS06670	COG1132	(ABC) transporter
AV941_RS06685	COG0228	four-way junction DNA binding
AV941_RS06690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV941_RS06695	COG0336	Belongs to the RNA methyltransferase TrmD family
AV941_RS06700	COG0335	large ribosomal subunit rRNA binding
AV941_RS06705	COG2860	membrane
AV941_RS06715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV941_RS06720	COG1605	Chorismate mutase
AV941_RS06720	COG0287	Prephenate dehydrogenase
AV941_RS06725	COG1605	Chorismate mutase
AV941_RS06725	COG0077	Prephenate dehydratase
AV941_RS06730	COG0745	RESPONSE REGULATOR receiver
AV941_RS06735	COG0023	Translation Initiation Factor
AV941_RS06765	COG2205	protein histidine kinase activity
AV941_RS06775	COG2204	response regulator
AV941_RS06800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV941_RS06805	COG0494	nUDIX hydrolase
AV941_RS06810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AV941_RS06815	COG0632	four-way junction helicase activity
AV941_RS06820	COG2255	four-way junction helicase activity
AV941_RS06825	COG0824	Thioesterase
AV941_RS06830	COG0811	peptide transport
AV941_RS06845	COG0823	Involved in the tonB-independent uptake of proteins
AV941_RS06850	COG2885	chlorophyll binding
AV941_RS06855	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AV941_RS06880	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AV941_RS06900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AV941_RS06915	COG4667	esterase of the alpha-beta hydrolase superfamily
AV941_RS06920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV941_RS06930	COG0784	Response regulator, receiver
AV941_RS06930	COG2205	protein histidine kinase activity
AV941_RS06945	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AV941_RS06950	COG3038	cytochrome b561
AV941_RS06970	COG0583	DNA-binding transcription factor activity
AV941_RS06975	COG1451	nucleotide metabolic process
AV941_RS06985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_RS06995	COG1309	transcriptional regulator
AV941_RS07000	COG4774	siderophore transport
AV941_RS07020	COG3706	GGDEF domain
AV941_RS07030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV941_RS07030	COG3008	intermembrane lipid transfer
AV941_RS07035	COG2995	paraquat-inducible protein a
AV941_RS07050	COG0017	Asparaginyl-tRNA synthetase
AV941_RS07065	COG0189	ligase activity
AV941_RS07095	COG0156	8-amino-7-oxononanoate synthase activity
AV941_RS07100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_RS07110	COG3340	Belongs to the peptidase S51 family
AV941_RS07115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV941_RS07120	COG4139	cobalamin transport
AV941_RS07125	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AV941_RS07130	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AV941_RS07145	COG5265	(ABC) transporter
AV941_RS07150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV941_RS07160	COG0745	RESPONSE REGULATOR receiver
AV941_RS07190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV941_RS07225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_RS07240	COG2755	lipolytic protein G-D-S-L family
AV941_RS07245	COG4181	ATPase activity
AV941_RS07250	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV941_RS07255	COG1090	epimerase
AV941_RS07260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV941_RS07265	COG0628	permease
AV941_RS07290	COG2350	Protein conserved in bacteria
AV941_RS07295	COG0159	tryptophan synthase activity
AV941_RS07305	COG0135	phosphoribosylanthranilate isomerase activity
AV941_RS07305	COG0134	indole-3-glycerol-phosphate synthase activity
AV941_RS07310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV941_RS07320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AV941_RS07325	COG0613	PHP domain protein
AV941_RS07330	COG0009	L-threonylcarbamoyladenylate synthase
AV941_RS07340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV941_RS07350	COG0656	L-ascorbic acid biosynthetic process
AV941_RS07355	COG0110	maltose O-acetyltransferase activity
AV941_RS07370	COG2733	membrane
AV941_RS07390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS07395	COG0500	methyltransferase
AV941_RS07400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_RS07405	COG0497	DNA recombination
AV941_RS07410	COG0783	Belongs to the Dps family
AV941_RS07415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AV941_RS07420	COG1454	alcohol dehydrogenase
AV941_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS07435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV941_RS07440	COG2610	gluconate transmembrane transporter activity
AV941_RS07445	COG4771	TonB-dependent receptor
AV941_RS07455	COG2198	Histidine kinase
AV941_RS07455	COG0784	Response regulator, receiver
AV941_RS07455	COG2205	protein histidine kinase activity
AV941_RS07460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV941_RS07470	COG0484	heat shock protein binding
AV941_RS07475	COG3909	cytochrome
AV941_RS07480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV941_RS07495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV941_RS07500	COG0505	Belongs to the CarA family
AV941_RS07505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV941_RS07510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_RS07535	COG0857	belongs to the CobB CobQ family
AV941_RS07535	COG0280	phosphate acetyltransferase
AV941_RS07550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AV941_RS07555	COG4535	Mg2 and Co2 transporter CorC
AV941_RS07565	COG1702	phosphate starvation-inducible protein PhoH
AV941_RS07575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_RS07615	COG1607	acyl-coa hydrolase
AV941_RS07620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV941_RS07630	COG1115	amino acid carrier protein
AV941_RS07680	COG0012	GTP binding
AV941_RS07695	COG1064	alcohol dehydrogenase
AV941_RS07710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV941_RS07720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV941_RS07725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV941_RS07730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV941_RS07740	COG2890	protein-(glutamine-N5) methyltransferase activity
AV941_RS07745	COG3437	response regulator, receiver
AV941_RS07745	COG0784	Response regulator, receiver
AV941_RS07755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AV941_RS07765	COG0583	DNA-binding transcription factor activity
AV941_RS07775	COG2363	Small membrane protein
AV941_RS07795	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AV941_RS07800	COG0515	serine threonine protein kinase
AV941_RS07805	COG2116	formate transmembrane transporter activity
AV941_RS07820	COG0714	Associated with various cellular activities
AV941_RS07825	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AV941_RS07830	COG0033	Phosphoglucomutase
AV941_RS07835	COG0058	SHG alpha-glucan phosphorylase activity
AV941_RS07845	COG2988	succinylglutamate desuccinylase activity
AV941_RS07880	COG1393	Belongs to the ArsC family
AV941_RS07905	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV941_RS07935	COG5001	Diguanylate cyclase
AV941_RS07935	COG3300	MHYT domain
AV941_RS07960	COG2249	NAD(P)H dehydrogenase (quinone) activity
AV941_RS07980	COG1733	regulation of RNA biosynthetic process
AV941_RS07985	COG3447	MASE1 domain protein
AV941_RS07985	COG5001	Diguanylate cyclase
AV941_RS07985	COG5002	protein histidine kinase activity
AV941_RS07995	COG0402	S-adenosylhomocysteine deaminase activity
AV941_RS08000	COG2351	hydroxyisourate hydrolase activity
AV941_RS08015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_RS08025	COG1309	transcriptional regulator
AV941_RS08040	COG2252	PERMEase
AV941_RS08045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV941_RS08060	COG4251	negative regulation of phosphorylation
AV941_RS08060	COG3706	GGDEF domain
AV941_RS08060	COG5001	Diguanylate cyclase
AV941_RS08060	COG2203	Gaf domain
AV941_RS08065	COG4251	negative regulation of phosphorylation
AV941_RS08065	COG5001	Diguanylate cyclase
AV941_RS08065	COG3706	GGDEF domain
AV941_RS08065	COG2203	Gaf domain
AV941_RS08070	COG2205	protein histidine kinase activity
AV941_RS08070	COG0784	Response regulator, receiver
AV941_RS08085	COG2233	PERMEase
AV941_RS08100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV941_RS08105	COG0730	response to heat
AV941_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS08150	COG3001	Fructosamine kinase
AV941_RS08160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV941_RS08180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV941_RS08190	COG1596	polysaccharide export
AV941_RS08195	COG0489	protein tyrosine kinase activity
AV941_RS08200	COG4464	protein tyrosine phosphatase activity
AV941_RS08255	COG1216	Glycosyl transferase, family 2
AV941_RS08270	COG1215	transferase activity, transferring glycosyl groups
AV941_RS08275	COG0438	transferase activity, transferring glycosyl groups
AV941_RS08285	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AV941_RS08305	COG0072	phenylalanine-tRNA ligase activity
AV941_RS08305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_RS08320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV941_RS08330	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_RS08335	COG2096	Adenosyltransferase
AV941_RS08345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV941_RS08355	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV941_RS08380	COG0708	Exodeoxyribonuclease III
AV941_RS08415	COG2814	Major facilitator Superfamily
AV941_RS08450	COG4770	biotin carboxylase activity
AV941_RS08455	COG1024	Enoyl-CoA hydratase
AV941_RS08460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV941_RS08465	COG1960	acyl-CoA dehydrogenase activity
AV941_RS08470	COG0789	Transcriptional regulator
AV941_RS08475	COG0183	Belongs to the thiolase family
AV941_RS08490	COG3706	GGDEF domain
AV941_RS08500	COG2925	Exonuclease
AV941_RS08505	COG0582	viral genome integration into host DNA
AV941_RS08545	COG0531	amino acid
AV941_RS08545	COG1674	ftsk spoiiie
AV941_RS08590	COG2197	response regulator
AV941_RS08605	COG3617	BRO family, N-terminal domain
AV941_RS08685	COG0305	Participates in initiation and elongation during chromosome replication
AV941_RS08775	COG3728	DNA packaging
AV941_RS08775	COG5484	DNA packaging
AV941_RS08925	COG1643	Atp-dependent helicase
AV941_RS08945	COG3321	synthase
AV941_RS08945	COG0604	alcohol dehydrogenase
AV941_RS08950	COG0328	RNA-DNA hybrid ribonuclease activity
AV941_RS08955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV941_RS08985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV941_RS08990	COG1136	(ABC) transporter
AV941_RS08995	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV941_RS09010	COG3724	N-succinylarginine dihydrolase activity
AV941_RS09015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AV941_RS09030	COG0746	molybdenum cofactor guanylyltransferase activity
AV941_RS09035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AV941_RS09040	COG0243	molybdopterin cofactor binding
AV941_RS09045	COG2153	protein acetylation
AV941_RS09060	COG1530	ribonuclease E activity
AV941_RS09075	COG0424	maF-like protein
AV941_RS09080	COG1399	metal-binding, possibly nucleic acid-binding protein
AV941_RS09090	COG0416	fatty acid biosynthetic process
AV941_RS09095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV941_RS09100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AV941_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV941_RS09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV941_RS09125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV941_RS09140	COG0084	hydrolase, TatD family'
AV941_RS09150	COG0702	epimerase
AV941_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS09180	COG0596	Alpha beta hydrolase
AV941_RS09190	COG0183	Belongs to the thiolase family
AV941_RS09195	COG1960	acyl-CoA dehydrogenase activity
AV941_RS09215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_RS09225	COG0246	Mannitol dehydrogenase
AV941_RS09250	COG0668	transmembrane transport
AV941_RS09255	COG4771	TonB-dependent receptor
AV941_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_RS09275	COG2205	protein histidine kinase activity
AV941_RS09280	COG3437	response regulator, receiver
AV941_RS09290	COG0195	Participates in both transcription termination and antitermination
AV941_RS09305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV941_RS09320	COG1187	pseudouridine synthase activity
AV941_RS09330	COG3153	acetyltransferase
AV941_RS09330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_RS09395	COG1032	radical SAM domain protein
AV941_RS09410	COG4771	TonB-dependent receptor
AV941_RS09415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_RS09425	COG4134	Bacterial extracellular solute-binding protein
AV941_RS09435	COG4136	ATPase activity
AV941_RS09440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV941_RS09465	COG3706	GGDEF domain
AV941_RS09465	COG2203	Gaf domain
AV941_RS09465	COG5001	Diguanylate cyclase
AV941_RS09465	COG4251	negative regulation of phosphorylation
AV941_RS09555	COG1902	pentaerythritol trinitrate reductase activity
AV941_RS09565	COG2867	negative regulation of translational initiation
AV941_RS09570	COG2914	Belongs to the UPF0125 (RnfH) family
AV941_RS09580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_RS09585	COG4771	TonB-dependent receptor
AV941_RS09590	COG0457	Tetratricopeptide repeat
AV941_RS09605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV941_RS09605	COG0574	Belongs to the PEP-utilizing enzyme family
AV941_RS09645	COG2850	peptidyl-arginine hydroxylation
AV941_RS09655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV941_RS09660	COG2915	High frequency lysogenization protein hflD homolog
AV941_RS09665	COG0482	sulfurtransferase activity
AV941_RS09670	COG1187	pseudouridine synthase activity
AV941_RS09680	COG1278	Cold shock
AV941_RS09685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV941_RS09690	COG0542	response to heat
AV941_RS09695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV941_RS09700	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV941_RS09705	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AV941_RS09710	COG0492	ferredoxin-NADP+ reductase activity
AV941_RS09720	COG3091	SprT-like family
AV941_RS09725	COG0616	signal peptide processing
AV941_RS09740	COG0778	Nitroreductase
AV941_RS09750	COG0252	asparaginase activity
AV941_RS09755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV941_RS09760	COG0321	lipoyl(octanoyl) transferase activity
AV941_RS09765	COG2921	Belongs to the UPF0250 family
AV941_RS09770	COG1686	Belongs to the peptidase S11 family
AV941_RS09775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV941_RS09780	COG0772	Belongs to the SEDS family
AV941_RS09785	COG0768	penicillin binding
AV941_RS09790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV941_RS09795	COG0799	negative regulation of ribosome biogenesis
AV941_RS09805	COG1466	dna polymerase III delta subunit
AV941_RS09810	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AV941_RS09815	COG0495	leucyl-tRNA aminoacylation
AV941_RS09825	COG1067	ATP-dependent peptidase activity
AV941_RS09830	COG0596	Alpha beta hydrolase
AV941_RS09845	COG1534	Rna-binding protein
AV941_RS09850	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV941_RS09855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV941_RS09860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AV941_RS09865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV941_RS09870	COG0149	triose-phosphate isomerase activity
AV941_RS09875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV941_RS09885	COG3300	MHYT domain
AV941_RS09885	COG5001	Diguanylate cyclase
AV941_RS09905	COG1803	Methylglyoxal synthase
AV941_RS09905	COG1597	lipid kinase activity
AV941_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS09920	COG0561	phosphatase activity
AV941_RS09940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_RS09945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV941_RS09950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AV941_RS09965	COG1185	polyribonucleotide nucleotidyltransferase activity
AV941_RS09990	COG1819	glycosyl
AV941_RS10100	COG4372	Transposase
AV941_RS10130	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AV941_RS10135	COG1196	nuclear chromosome segregation
AV941_RS10145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV941_RS10160	COG1132	(ABC) transporter
AV941_RS10165	COG1663	tetraacyldisaccharide 4'-kinase activity
AV941_RS10200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV941_RS10205	COG0435	Glutathione S-transferase
AV941_RS10210	COG1741	Belongs to the pirin family
AV941_RS10215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV941_RS10225	COG0372	Belongs to the citrate synthase family
AV941_RS10235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV941_RS10240	COG1053	succinate dehydrogenase
AV941_RS10245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AV941_RS10250	COG0567	Dehydrogenase, E1 component
AV941_RS10255	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_RS10290	COG4667	esterase of the alpha-beta hydrolase superfamily
AV941_RS10310	COG0366	Alpha amylase catalytic
AV941_RS10335	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS10340	COG2267	carboxylic ester hydrolase activity
AV941_RS10350	COG0616	signal peptide processing
AV941_RS10370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_RS10375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV941_RS10380	COG0386	Belongs to the glutathione peroxidase family
AV941_RS10385	COG2084	Dehydrogenase
AV941_RS10395	COG1960	acyl-CoA dehydrogenase activity
AV941_RS10400	COG1024	Enoyl-CoA hydratase
AV941_RS10405	COG2226	methyltransferase
AV941_RS10410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV941_RS10415	COG3083	sulfuric ester hydrolase activity
AV941_RS10420	COG3082	Protein of unknown function (DUF1414)
AV941_RS10425	COG3081	Nucleoid-associated protein
AV941_RS10455	COG3275	phosphorelay sensor kinase activity
AV941_RS10460	COG3279	Response regulator of the LytR AlgR family
AV941_RS10465	COG0205	6-phosphofructokinase activity
AV941_RS10480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_RS10495	COG0745	RESPONSE REGULATOR receiver
AV941_RS10505	COG1054	Belongs to the UPF0176 family
AV941_RS10515	COG0513	Belongs to the DEAD box helicase family
AV941_RS10525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AV941_RS10530	COG0583	DNA-binding transcription factor activity
AV941_RS10550	COG1760	l-serine dehydratase
AV941_RS10570	COG1322	Protein conserved in bacteria
AV941_RS10575	COG1404	Belongs to the peptidase S8 family
AV941_RS10580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV941_RS10585	COG0022	dehydrogenase e1 component
AV941_RS10595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV941_RS10600	COG0515	serine threonine protein kinase
AV941_RS10605	COG1946	Acyl-CoA thioesterase
AV941_RS10615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV941_RS10625	COG1956	GAF domain-containing protein
AV941_RS10640	COG0793	Belongs to the peptidase S41A family
AV941_RS10645	COG0733	neurotransmitter:sodium symporter activity
AV941_RS10650	COG1757	Na H antiporter
AV941_RS10655	COG0308	aminopeptidase N
AV941_RS10685	COG2902	Dehydrogenase
AV941_RS10690	COG0167	dihydroorotate dehydrogenase activity
AV941_RS10705	COG0488	(ABC) transporter
AV941_RS10715	COG3130	regulation of translation
AV941_RS10720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV941_RS10730	COG0415	Belongs to the DNA photolyase family
AV941_RS10735	COG0415	Belongs to the DNA photolyase family
AV941_RS10740	COG0415	Belongs to the DNA photolyase family
AV941_RS10745	COG3046	protein related to deoxyribodipyrimidine photolyase
AV941_RS10760	COG4974	Belongs to the 'phage' integrase family
AV941_RS10770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV941_RS10775	COG0589	response to stress
AV941_RS10785	COG0069	glutamate synthase activity
AV941_RS10800	COG2193	ferroxidase activity
AV941_RS10810	COG3278	Belongs to the heme-copper respiratory oxidase family
AV941_RS10825	COG2010	Cytochrome c
AV941_RS10850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV941_RS10855	COG0589	response to stress
AV941_RS10860	COG0037	tRNA processing
AV941_RS10865	COG1752	Esterase of the alpha-beta hydrolase superfamily
AV941_RS10885	COG1280	lysine exporter protein (LysE YggA)
AV941_RS10895	COG2897	thiosulfate sulfurtransferase activity
AV941_RS10900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AV941_RS10905	COG3148	PFAM DTW domain containing protein
AV941_RS10930	COG0322	excinuclease ABC activity
AV941_RS10935	COG2197	response regulator
AV941_RS10940	COG0436	Aminotransferase
AV941_RS10955	COG2259	Doxx family
AV941_RS10960	COG0583	DNA-binding transcription factor activity
AV941_RS10970	COG0670	Belongs to the BI1 family
AV941_RS10975	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AV941_RS10990	COG2920	part of a sulfur-relay system
AV941_RS11020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV941_RS11030	COG0531	amino acid
AV941_RS11030	COG1674	ftsk spoiiie
AV941_RS11040	COG0686	Belongs to the AlaDH PNT family
AV941_RS11045	COG0284	orotidine-5'-phosphate decarboxylase activity
AV941_RS11050	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV941_RS11065	COG0776	regulation of translation
AV941_RS11070	COG0539	negative regulation of cytoplasmic translation
AV941_RS11075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV941_RS11080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV941_RS11085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV941_RS11095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_RS11100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV941_RS11105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV941_RS11110	COG0633	Ferredoxin
AV941_RS11140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV941_RS11145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV941_RS11155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV941_RS11165	COG4783	chaperone-mediated protein folding
AV941_RS11175	COG1393	Belongs to the ArsC family
AV941_RS11190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV941_RS11205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV941_RS11215	COG1960	acyl-CoA dehydrogenase activity
AV941_RS11240	COG0572	uridine kinase
AV941_RS11245	COG3769	mannosylglycerate metabolic process
AV941_RS11250	COG1215	transferase activity, transferring glycosyl groups
AV941_RS11255	COG0366	Alpha amylase catalytic
AV941_RS11265	COG0303	'Molybdopterin
AV941_RS11270	COG0534	Mate efflux family protein
AV941_RS11285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV941_RS11290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV941_RS11320	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AV941_RS11370	COG0405	Gamma-glutamyltransferase
AV941_RS11375	COG1024	Enoyl-CoA hydratase
AV941_RS11420	COG1448	Aminotransferase
AV941_RS11430	COG1671	Belongs to the UPF0178 family
AV941_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS11445	COG1960	acyl-CoA dehydrogenase activity
AV941_RS11450	COG0662	Cupin 2, conserved barrel domain protein
AV941_RS11450	COG2207	Transcriptional regulator
AV941_RS11465	COG1505	serine-type exopeptidase activity
AV941_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS11505	COG0596	Alpha beta hydrolase
AV941_RS11515	COG0716	FMN binding
AV941_RS11525	COG0735	belongs to the Fur family
AV941_RS11535	COG1984	allophanate hydrolase subunit 2
AV941_RS11540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AV941_RS11545	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AV941_RS11550	COG2996	Protein conserved in bacteria
AV941_RS11555	COG1765	OsmC-like protein
AV941_RS11560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS11570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_RS11585	COG0436	Aminotransferase
AV941_RS11595	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV941_RS11610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_RS11610	COG2010	Cytochrome c
AV941_RS11615	COG2080	2 iron, 2 sulfur cluster binding
AV941_RS11640	COG1073	alpha beta
AV941_RS11645	COG2207	Transcriptional regulator
AV941_RS11655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV941_RS11660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV941_RS11685	COG3012	SEC-C Motif Domain Protein
AV941_RS11690	COG0604	alcohol dehydrogenase
AV941_RS11700	COG1960	acyl-CoA dehydrogenase activity
AV941_RS11710	COG4771	TonB-dependent receptor
AV941_RS11735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV941_RS11755	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AV941_RS11760	COG0315	cyclic pyranopterin monophosphate synthase activity
AV941_RS11765	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV941_RS11780	COG2161	toxin-antitoxin pair type II binding
AV941_RS11785	COG4115	mRNA cleavage
AV941_RS11800	COG0436	Aminotransferase
AV941_RS11805	COG3268	Saccharopine dehydrogenase
AV941_RS11810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV941_RS11825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV941_RS11830	COG4206	TonB-dependent receptor
AV941_RS11840	COG5006	permease, DMT superfamily
AV941_RS11855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AV941_RS11860	COG1074	ATP-dependent DNA helicase activity
AV941_RS11865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AV941_RS11875	COG1022	Amp-dependent synthetase and ligase
AV941_RS11880	COG2203	Gaf domain
AV941_RS11880	COG5001	Diguanylate cyclase
AV941_RS11880	COG4251	negative regulation of phosphorylation
AV941_RS11880	COG3706	GGDEF domain
AV941_RS11900	COG0583	DNA-binding transcription factor activity
AV941_RS11925	COG0640	Transcriptional regulator
AV941_RS11945	COG2204	response regulator
AV941_RS11955	COG4251	negative regulation of phosphorylation
AV941_RS11960	COG0784	Response regulator, receiver
AV941_RS11965	COG2205	protein histidine kinase activity
AV941_RS11965	COG0784	Response regulator, receiver
AV941_RS11990	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV941_RS12015	COG3139	Protein of unknown function (DUF1315)
AV941_RS12025	COG1115	amino acid carrier protein
AV941_RS12030	COG2866	Carboxypeptidase
AV941_RS12050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AV941_RS12060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV941_RS12065	COG1640	4-alpha-glucanotransferase
AV941_RS12070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AV941_RS12075	COG0676	glucose-6-phosphate 1-epimerase activity
AV941_RS12080	COG0800	Aldolase
AV941_RS12090	COG0129	dihydroxy-acid dehydratase activity
AV941_RS12105	COG1737	Transcriptional regulator
AV941_RS12110	COG0469	pyruvate kinase activity
AV941_RS12125	COG1960	acyl-CoA dehydrogenase activity
AV941_RS12145	COG0471	metal ion transport
AV941_RS12145	COG0490	domain, Protein
AV941_RS12160	COG1737	Transcriptional regulator
AV941_RS12165	COG0469	pyruvate kinase activity
AV941_RS12170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_RS12190	COG2823	Periplasmic or secreted lipoprotein
AV941_RS12215	COG3665	Urea carboxylase-associated protein
AV941_RS12245	COG2356	endonuclease I
AV941_RS12250	COG0840	transmembrane signaling receptor activity
AV941_RS12265	COG0583	DNA-binding transcription factor activity
AV941_RS12270	COG1979	alcohol dehydrogenase
AV941_RS12275	COG5001	Diguanylate cyclase
AV941_RS12285	COG0784	Response regulator, receiver
AV941_RS12285	COG3437	response regulator, receiver
AV941_RS12375	COG0471	metal ion transport
AV941_RS12385	COG0489	protein tyrosine kinase activity
AV941_RS12390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_RS12390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_RS12395	COG0668	transmembrane transport
AV941_RS12400	COG2226	methyltransferase
AV941_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_RS12410	COG0741	lytic transglycosylase activity
AV941_RS12410	COG1388	LysM domain
AV941_RS12425	COG0215	cysteine-tRNA ligase activity
AV941_RS12430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV941_RS12435	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV941_RS12445	COG2268	Band 7 protein
AV941_RS12460	COG1733	regulation of RNA biosynthetic process
AV941_RS12465	COG0604	alcohol dehydrogenase
AV941_RS12470	COG0753	catalase activity
AV941_RS12475	COG0604	alcohol dehydrogenase
AV941_RS12480	COG0583	DNA-binding transcription factor activity
AV941_RS12515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AV941_RS12520	COG1286	toxin biosynthetic process
AV941_RS12525	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AV941_RS12530	COG0285	dihydrofolate synthase activity
AV941_RS12550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV941_RS12555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV941_RS12575	COG3609	addiction module antidote protein, CC2985 family
AV941_RS12585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV941_RS12590	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_RS12600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AV941_RS12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV941_RS12635	COG0789	Transcriptional regulator
AV941_RS12640	COG0604	alcohol dehydrogenase
AV941_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS12670	COG1119	ATPase activity
AV941_RS12675	COG2031	fatty acid transporter
AV941_RS12680	COG5002	protein histidine kinase activity
AV941_RS12680	COG2205	protein histidine kinase activity
AV941_RS12680	COG0784	Response regulator, receiver
AV941_RS12690	COG0612	Peptidase, M16
AV941_RS12705	COG3101	peptidyl-lysine hydroxylation
AV941_RS12730	COG1902	pentaerythritol trinitrate reductase activity
AV941_RS12730	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV941_RS12755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV941_RS12765	COG4399	Belongs to the UPF0754 family
AV941_RS12790	COG1770	oligopeptidase
AV941_RS12795	COG2186	Transcriptional regulator
AV941_RS12805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV941_RS12810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV941_RS12820	COG2983	Belongs to the UPF0260 family
AV941_RS12825	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV941_RS12840	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AV941_RS12845	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_RS12850	COG2267	carboxylic ester hydrolase activity
AV941_RS12865	COG1214	PFAM Peptidase M22, glycoprotease
AV941_RS12870	COG1199	ATP-dependent helicase activity
AV941_RS12920	COG4771	TonB-dependent receptor
AV941_RS12930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV941_RS12935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV941_RS12940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV941_RS12945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV941_RS12945	COG0131	Imidazoleglycerol-phosphate dehydratase
AV941_RS12950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV941_RS12980	COG2116	formate transmembrane transporter activity
AV941_RS12985	COG0612	Peptidase, M16
AV941_RS13010	COG0326	Molecular chaperone. Has ATPase activity
AV941_RS13015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV941_RS13035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV941_RS13040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV941_RS13050	COG3220	belongs to the UPF0276 family
AV941_RS13060	COG1136	(ABC) transporter
AV941_RS13060	COG0577	efflux transmembrane transporter activity
AV941_RS13070	COG5001	Diguanylate cyclase
AV941_RS13070	COG4251	negative regulation of phosphorylation
AV941_RS13070	COG2203	Gaf domain
AV941_RS13070	COG3706	GGDEF domain
AV941_RS13090	COG1183	phosphatidylcholine synthase activity
AV941_RS13110	COG0277	FAD linked oxidase domain protein
AV941_RS13115	COG0542	response to heat
AV941_RS13140	COG1595	DNA-templated transcription, initiation
AV941_RS13155	COG4221	oxidoreductase activity
AV941_RS13170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AV941_RS13180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AV941_RS13190	COG0142	geranyltranstransferase activity
AV941_RS13200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV941_RS13205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AV941_RS13215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV941_RS13230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV941_RS13230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV941_RS13245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV941_RS13250	COG0488	(ABC) transporter
AV941_RS13260	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AV941_RS13270	COG0560	Phosphoserine phosphatase
AV941_RS13280	COG0084	hydrolase, TatD family'
AV941_RS13295	COG0571	ribonuclease III activity
AV941_RS13325	COG1595	DNA-templated transcription, initiation
AV941_RS13330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AV941_RS13345	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV941_RS13425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AV941_RS13430	COG1047	Peptidyl-prolyl cis-trans
AV941_RS13440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV941_RS13445	COG0196	riboflavin kinase activity
AV941_RS13450	COG0728	peptidoglycan biosynthetic process
AV941_RS13455	COG0268	Binds directly to 16S ribosomal RNA
AV941_RS13475	COG0385	Bile acid
AV941_RS13505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_RS13510	COG0776	regulation of translation
AV941_RS13515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV941_RS13520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV941_RS13525	COG0740	serine-type endopeptidase activity
AV941_RS13530	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV941_RS13575	COG1720	tRNA m6t6A37 methyltransferase activity
AV941_RS13585	COG1234	tRNA 3'-trailer cleavage
AV941_RS13595	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV941_RS13610	COG0517	IMP dehydrogenase activity
AV941_RS13610	COG0516	GMP reductase activity
AV941_RS13615	COG1570	exodeoxyribonuclease VII activity
AV941_RS13635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_RS13640	COG2976	Protein conserved in bacteria
AV941_RS13665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV941_RS13675	COG2166	iron-sulfur cluster assembly
AV941_RS13690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV941_RS13695	COG0719	Fe-S assembly protein
AV941_RS13700	COG0396	ATPase activity
AV941_RS13705	COG0719	Fe-S assembly protein
AV941_RS13710	COG1104	cysteine desulfurase activity
AV941_RS13720	COG2072	flavoprotein involved in K transport
AV941_RS13725	COG1045	serine acetyltransferase
AV941_RS13730	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AV941_RS13735	COG0483	inositol monophosphate 1-phosphatase activity
AV941_RS13750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV941_RS13755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV941_RS13760	COG1862	Preprotein translocase
AV941_RS13765	COG0343	queuine tRNA-ribosyltransferase activity
AV941_RS13785	COG1842	Phage shock protein A
AV941_RS13790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AV941_RS13810	COG0754	glutathionylspermidine amidase activity
AV941_RS13840	COG2066	Belongs to the glutaminase family
AV941_RS13845	COG1785	Belongs to the alkaline phosphatase family
AV941_RS13850	COG0745	RESPONSE REGULATOR receiver
AV941_RS13925	COG0438	transferase activity, transferring glycosyl groups
AV941_RS13950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV941_RS13955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AV941_RS13985	COG2755	lipolytic protein G-D-S-L family
AV941_RS13985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AV941_RS13990	COG0367	asparagine synthase
AV941_RS13995	COG0438	transferase activity, transferring glycosyl groups
AV941_RS14005	COG2244	polysaccharide biosynthetic process
AV941_RS14035	COG0367	asparagine synthase
AV941_RS14070	COG0489	protein tyrosine kinase activity
AV941_RS14080	COG3409	Peptidoglycan-binding domain 1 protein
AV941_RS14080	COG3267	Type II secretory pathway component ExeA
AV941_RS14130	COG1560	Kdo2-lipid A biosynthetic process
AV941_RS14145	COG1960	acyl-CoA dehydrogenase activity
AV941_RS14160	COG3300	MHYT domain
AV941_RS14160	COG5001	Diguanylate cyclase
AV941_RS14165	COG1435	thymidine kinase activity
AV941_RS14175	COG1609	Transcriptional regulator
AV941_RS14180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV941_RS14210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV941_RS14215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV941_RS14220	COG1024	Enoyl-CoA hydratase
AV941_RS14220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
AV941_RS14255	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AV941_RS14280	COG1960	acyl-CoA dehydrogenase activity
AV941_RS14310	COG0745	RESPONSE REGULATOR receiver
AV941_RS14315	COG2205	protein histidine kinase activity
AV941_RS14355	COG2080	2 iron, 2 sulfur cluster binding
AV941_RS14360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AV941_RS14365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_RS14385	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_RS14390	COG4221	oxidoreductase activity
AV941_RS14395	COG0693	protein deglycase activity
AV941_RS14400	COG1295	ribonuclease BN
AV941_RS14440	COG2814	Major facilitator Superfamily
AV941_RS14455	COG0514	ATP-dependent DNA helicase (RecQ)
AV941_RS14485	COG4251	negative regulation of phosphorylation
AV941_RS14490	COG2133	pyrroloquinoline quinone binding
AV941_RS14520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV941_RS14525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_RS14540	COG0330	HflC and HflK could
AV941_RS14635	COG4772	TonB-dependent receptor
AV941_RS14720	COG4372	Transposase
AV941_RS14735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV941_RS14735	COG1017	nitric oxide dioxygenase activity
AV941_RS14740	COG3604	Transcriptional regulator
AV941_RS14755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV941_RS14755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AV941_RS14770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AV941_RS14775	COG2971	BadF BadG BcrA BcrD
AV941_RS14780	COG0583	DNA-binding transcription factor activity
AV941_RS14785	COG1620	l-lactate permease
AV941_RS14805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_RS14810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_RS14815	COG0006	proline dipeptidase activity
AV941_RS14830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV941_RS14845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AV941_RS14850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV941_RS14855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV941_RS14875	COG3313	Fe-S protein
AV941_RS14910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_RS14915	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_RS14920	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV941_RS14935	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV941_RS14940	COG3577	Aspartyl protease
AV941_RS14945	COG0157	Belongs to the NadC ModD family
AV941_RS14955	COG1459	type II secretion system
AV941_RS14960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AV941_RS14965	COG0237	dephospho-CoA kinase activity
AV941_RS14970	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV941_RS14975	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AV941_RS14980	COG3608	succinylglutamate desuccinylase aspartoacylase
AV941_RS14985	COG0494	nUDIX hydrolase
AV941_RS14995	COG0739	heme binding
AV941_RS15000	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV941_RS15005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AV941_RS15010	COG0849	cell division
AV941_RS15015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV941_RS15020	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV941_RS15025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV941_RS15035	COG0772	Belongs to the SEDS family
AV941_RS15040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV941_RS15050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV941_RS15055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV941_RS15060	COG0768	penicillin binding
AV941_RS15065	COG3116	cell division
AV941_RS15075	COG2001	Belongs to the MraZ family
AV941_RS15120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV941_RS15120	COG0678	peroxiredoxin activity
AV941_RS15145	COG2204	response regulator
AV941_RS15150	COG2205	protein histidine kinase activity
AV941_RS15150	COG0784	Response regulator, receiver
AV941_RS15175	COG0668	transmembrane transport
AV941_RS15180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV941_RS15185	COG0189	ligase activity
AV941_RS15190	COG1678	Uncharacterized ACR, COG1678
AV941_RS15195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV941_RS15220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AV941_RS15225	COG0762	integral membrane protein
AV941_RS15235	COG1902	pentaerythritol trinitrate reductase activity
AV941_RS15235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV941_RS15250	COG0625	glutathione transferase activity
AV941_RS15260	COG1764	response to oxidative stress
AV941_RS15280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV941_RS15290	COG2814	Major facilitator Superfamily
AV941_RS15295	COG0724	RNA recognition motif
AV941_RS15320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV941_RS15325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AV941_RS15330	COG0083	homoserine kinase activity
AV941_RS15345	COG0583	DNA-binding transcription factor activity
AV941_RS15360	COG0640	Transcriptional regulator
AV941_RS15370	COG0431	NADPH-dependent FMN reductase
AV941_RS15375	COG0798	PFAM Bile acid sodium symporter
AV941_RS15380	COG2201	protein-glutamate methylesterase activity
AV941_RS15385	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AV941_RS15395	COG0642	Histidine kinase
AV941_RS15420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV941_RS15445	COG1748	Saccharopine dehydrogenase
AV941_RS15460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AV941_RS15465	COG3107	peptidoglycan biosynthetic process
AV941_RS15475	COG0438	transferase activity, transferring glycosyl groups
AV941_RS15485	COG2823	Periplasmic or secreted lipoprotein
AV941_RS15505	COG4585	Histidine kinase
AV941_RS15510	COG2197	response regulator
AV941_RS15525	COG4771	TonB-dependent receptor
AV941_RS15535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AV941_RS15540	COG0372	Belongs to the citrate synthase family
AV941_RS15545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AV941_RS15550	COG2828	Protein conserved in bacteria
AV941_RS15555	COG2199	diguanylate cyclase activity
AV941_RS15555	COG2203	Gaf domain
AV941_RS15560	COG1940	carbohydrate kinase activity
AV941_RS15580	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AV941_RS15600	COG5002	protein histidine kinase activity
AV941_RS15600	COG0784	Response regulator, receiver
AV941_RS15600	COG2198	Histidine kinase
AV941_RS15605	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV941_RS15610	COG0070	glutamate synthase
AV941_RS15610	COG0069	glutamate synthase activity
AV941_RS15610	COG0067	glutamate synthase
AV941_RS15615	COG0493	'glutamate synthase
AV941_RS15630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_RS15635	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AV941_RS15640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV941_RS15645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_RS15660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV941_RS15665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AV941_RS15670	COG4942	peptidase
AV941_RS15675	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV941_RS15680	COG0738	Major facilitator superfamily
AV941_RS15690	COG1902	pentaerythritol trinitrate reductase activity
AV941_RS15710	COG0625	glutathione transferase activity
AV941_RS15735	COG2894	cell division
AV941_RS15740	COG0850	regulation of cytokinetic process
AV941_RS15750	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AV941_RS15765	COG1981	membrane
AV941_RS15780	COG1914	H( )-stimulated, divalent metal cation uptake system
AV941_RS15795	COG1217	gtp-binding protein TYPA
AV941_RS15800	COG0174	glutamine synthetase
AV941_RS15810	COG3852	Histidine kinase
AV941_RS15815	COG2204	response regulator
AV941_RS15820	COG3437	response regulator, receiver
AV941_RS15860	COG4999	Histidine kinase
AV941_RS15860	COG2205	protein histidine kinase activity
AV941_RS15860	COG3437	response regulator, receiver
AV941_RS15860	COG3850	Histidine kinase
AV941_RS15865	COG0525	valine-tRNA ligase activity
AV941_RS15870	COG2927	DNA polymerase III (CHI subunit)
AV941_RS15875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV941_RS15880	COG0795	lipopolysaccharide-transporting ATPase activity
AV941_RS15885	COG0795	lipopolysaccharide-transporting ATPase activity
AV941_RS15975	COG4974	Belongs to the 'phage' integrase family
AV941_RS15990	COG2856	Zn peptidase
AV941_RS16080	COG3250	beta-galactosidase activity
AV941_RS16090	COG4948	Mandelate Racemase Muconate Lactonizing
AV941_RS16095	COG3661	Belongs to the glycosyl hydrolase 67 family
AV941_RS16110	COG2203	Gaf domain
AV941_RS16110	COG2199	diguanylate cyclase activity
AV941_RS16135	COG0673	inositol 2-dehydrogenase activity
AV941_RS16145	COG0628	permease
AV941_RS16160	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV941_RS16165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV941_RS16170	COG4558	Periplasmic binding protein
AV941_RS16180	COG4206	TonB-dependent receptor
AV941_RS16190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV941_RS16220	COG1971	Probably functions as a manganese efflux pump
AV941_RS16230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AV941_RS16245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV941_RS16255	COG0679	Auxin Efflux Carrier
AV941_RS16285	COG1131	(ABC) transporter
AV941_RS16295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV941_RS16310	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AV941_RS16350	COG2205	protein histidine kinase activity
AV941_RS16360	COG3901	Regulator of nitric oxide reductase transcription
AV941_RS16360	COG0348	domain, Protein
AV941_RS16370	COG2197	response regulator
AV941_RS16395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_RS16410	COG4771	TonB-dependent receptor
AV941_RS16420	COG0583	DNA-binding transcription factor activity
AV941_RS16425	COG1304	FMN binding
AV941_RS16430	COG0277	FAD linked oxidase domain protein
AV941_RS16440	COG1462	curli production assembly transport component CsgG
AV941_RS16470	COG2197	response regulator
AV941_RS16485	COG0513	Belongs to the DEAD box helicase family
AV941_RS16520	COG2337	Toxic component of a toxin-antitoxin (TA) module
AV941_RS16550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV941_RS16555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV941_RS16555	COG2010	Cytochrome c
AV941_RS16570	COG2199	diguanylate cyclase activity
AV941_RS16570	COG2203	Gaf domain
AV941_RS16585	COG2124	cytochrome p450
AV941_RS16595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV941_RS16610	COG1271	oxidase subunit
AV941_RS16615	COG1294	oxidase, subunit
AV941_RS16635	COG3264	Mechanosensitive ion channel
AV941_RS16635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AV941_RS16675	COG0730	response to heat
AV941_RS16680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV941_RS16695	COG4191	Histidine kinase
AV941_RS16705	COG0417	DNA replication proofreading
AV941_RS16715	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_RS16755	COG1309	transcriptional regulator
AV941_RS16765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_RS16775	COG1573	uracil-dna glycosylase
AV941_RS16780	COG3300	MHYT domain
AV941_RS16780	COG5001	Diguanylate cyclase
AV941_RS16800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV941_RS16820	COG1983	PspC domain protein
AV941_RS16825	COG1842	Phage shock protein A
AV941_RS16835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_RS16860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV941_RS16870	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV941_RS16875	COG0204	Acyl-transferase
AV941_RS16880	COG0204	Acyl-transferase
AV941_RS16885	COG0668	transmembrane transport
AV941_RS16900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV941_RS16905	COG0733	neurotransmitter:sodium symporter activity
AV941_RS16920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV941_RS16945	COG0848	biopolymer transport protein
AV941_RS16955	COG0457	Tetratricopeptide repeat
AV941_RS16960	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AV941_RS16970	COG1215	transferase activity, transferring glycosyl groups
AV941_RS16985	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AV941_RS16990	COG0702	epimerase
AV941_RS17015	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AV941_RS17025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_RS17035	COG0583	DNA-binding transcription factor activity
AV941_RS17040	COG0121	glutamine amidotransferase
AV941_RS17045	COG4682	membrane
AV941_RS17065	COG1953	Uracil, thiamine, allantoin
AV941_RS17070	COG4771	TonB-dependent receptor
AV941_RS17080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV941_RS17085	COG0778	Nitroreductase
AV941_RS17090	COG0596	Alpha beta hydrolase
AV941_RS17095	COG0251	oxidation-reduction process
AV941_RS17100	COG1335	isochorismatase
AV941_RS17105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_RS17110	COG1309	transcriptional regulator
AV941_RS17125	COG4628	conserved protein (DUF2132)
AV941_RS17130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_RS17140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AV941_RS17150	COG1477	protein flavinylation
AV941_RS17155	COG2871	sodium ion transport
AV941_RS17160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_RS17165	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_RS17170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_RS17175	COG1805	sodium ion transport
AV941_RS17180	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_RS17185	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV941_RS17190	COG0545	Peptidyl-prolyl cis-trans isomerase
AV941_RS17195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV941_RS17210	COG0039	L-malate dehydrogenase activity
AV941_RS17215	COG1438	arginine binding
AV941_RS17240	COG0572	uridine kinase
AV941_RS17245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AV941_RS17270	COG2176	DNA-directed DNA polymerase activity
AV941_RS17275	COG0517	IMP dehydrogenase activity
AV941_RS17275	COG1125	glycine betaine transport
AV941_RS17280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_RS17290	COG2205	protein histidine kinase activity
AV941_RS17300	COG0189	ligase activity
AV941_RS17310	COG4067	protein conserved in archaea
AV941_RS17310	COG0189	ligase activity
AV941_RS17325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV941_RS17335	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV941_RS17340	COG0667	Aldo Keto reductase
AV941_RS17360	COG5001	Diguanylate cyclase
AV941_RS17395	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV941_RS17405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV941_RS17445	COG2274	protein secretion by the type I secretion system
AV941_RS17450	COG0583	DNA-binding transcription factor activity
AV941_RS17475	COG0438	transferase activity, transferring glycosyl groups
AV941_RS17475	COG1216	Glycosyl transferase, family 2
AV941_RS17515	COG0457	Tetratricopeptide repeat
AV941_RS17550	COG0463	Glycosyl transferase, family 2
AV941_RS17550	COG1216	Glycosyl transferase, family 2
AV941_RS17650	COG4372	Transposase
AV941_RS17700	COG2161	toxin-antitoxin pair type II binding
AV941_RS17710	COG0202	RNA polymerase activity
AV941_RS17735	COG0201	protein transport
AV941_RS17755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV941_RS17790	COG5002	protein histidine kinase activity
AV941_RS17790	COG0784	Response regulator, receiver
AV941_RS17810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV941_RS17815	COG0557	exoribonuclease II activity
AV941_RS17860	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AV941_RS17875	COG0543	2 iron, 2 sulfur cluster binding
AV941_RS17890	COG2234	aminopeptidase activity
AV941_RS17900	COG4251	negative regulation of phosphorylation
AV941_RS17910	COG1271	oxidase subunit
AV941_RS17915	COG1294	oxidase, subunit
AV941_RS17925	COG1522	sequence-specific DNA binding
AV941_RS17935	COG1278	Cold shock
AV941_RS17940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV941_RS17960	COG0339	signal peptide processing
AV941_RS17965	COG2201	protein-glutamate methylesterase activity
AV941_RS17975	COG3852	Histidine kinase
AV941_RS17985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_RS17990	COG0243	molybdopterin cofactor binding
AV941_RS17995	COG0823	Involved in the tonB-independent uptake of proteins
AV941_RS17995	COG1506	peptidase
AV941_RS17995	COG4946	Tricorn protease homolog
AV941_RS18040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_RS18050	COG2197	response regulator
AV941_RS18060	COG0189	ligase activity
AV941_RS18080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV941_RS18085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV941_RS18090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV941_RS18105	COG0281	malic enzyme
AV941_RS18115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AV941_RS18145	COG0456	acetyltransferase
AV941_RS18155	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV941_RS18160	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV941_RS18165	COG2177	Part of the ABC transporter FtsEX involved in
AV941_RS18170	COG2884	Cell division ATP-binding protein ftsE
AV941_RS18175	COG0552	protein localization to endoplasmic reticulum
AV941_RS18180	COG0742	ribosomal rna small subunit methyltransferase
AV941_RS18190	COG2095	MarC family integral membrane protein
AV941_RS18210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV941_RS18215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV941_RS18220	COG0617	tRNA 3'-terminal CCA addition
AV941_RS18225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AV941_RS18240	COG0076	glutamate decarboxylase activity
AV941_RS18255	COG0842	Transport permease protein
AV941_RS18260	COG1131	(ABC) transporter
AV941_RS18265	COG0745	RESPONSE REGULATOR receiver
AV941_RS18270	COG2205	protein histidine kinase activity
AV941_RS18275	COG4774	siderophore transport
AV941_RS18295	COG1253	flavin adenine dinucleotide binding
AV941_RS18305	COG1966	Carbon starvation protein
AV941_RS18315	COG0657	acetylesterase activity
AV941_RS18335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV941_RS18340	COG0049	tRNA binding
AV941_RS18345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV941_RS18350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV941_RS18355	COG0085	RNA polymerase activity
AV941_RS18360	COG0222	ribosome binding
AV941_RS18365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV941_RS18370	COG0081	regulation of translation
AV941_RS18375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV941_RS18395	COG0250	Participates in transcription elongation, termination and antitermination
AV941_RS18400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV941_RS18410	COG1132	(ABC) transporter
AV941_RS18415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AV941_RS18420	COG3590	peptidase
AV941_RS18430	COG0513	Belongs to the DEAD box helicase family
AV941_RS18435	COG0418	dihydroorotase activity
AV941_RS18440	COG3040	lipid binding
AV941_RS18445	COG4989	oxidoreductase activity
AV941_RS18450	COG0346	lactoylglutathione lyase activity
AV941_RS18455	COG0668	transmembrane transport
AV941_RS18470	COG0302	gtp cyclohydrolase
AV941_RS18480	COG2957	Belongs to the agmatine deiminase family
AV941_RS18485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_RS18500	COG1201	RNA secondary structure unwinding
AV941_RS18510	COG1793	dna ligase
AV941_RS18515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV941_RS18520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV941_RS18530	COG1410	methionine synthase
AV941_RS18530	COG0646	methionine synthase
AV941_RS18535	COG0625	glutathione transferase activity
AV941_RS18540	COG0625	glutathione transferase activity
AV941_RS18550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AV941_RS18565	COG1012	belongs to the aldehyde dehydrogenase family
AV941_RS18570	COG0028	Belongs to the TPP enzyme family
AV941_RS18580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV941_RS18585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AV941_RS18595	COG0330	HflC and HflK could
AV941_RS18600	COG0330	HflC and HflK could
AV941_RS18605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV941_RS18610	COG1923	regulation of RNA biosynthetic process
AV941_RS18615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV941_RS18630	COG0802	atpase or kinase
AV941_RS18635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV941_RS18635	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AV941_RS18640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV941_RS18660	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AV941_RS18665	COG0735	belongs to the Fur family
AV941_RS18685	COG0305	Participates in initiation and elongation during chromosome replication
AV941_RS18710	COG2258	MOSC domain
AV941_RS18740	COG2205	protein histidine kinase activity
AV941_RS18760	COG0840	transmembrane signaling receptor activity
AV941_RS18765	COG5002	protein histidine kinase activity
AV941_RS18770	COG0840	transmembrane signaling receptor activity
AV941_RS18795	COG1757	Na H antiporter
AV941_RS18800	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_RS18810	COG2723	6-phospho-beta-galactosidase activity
AV941_RS18815	COG1609	Transcriptional regulator
AV941_RS18820	COG2814	Major facilitator Superfamily
AV941_RS18820	COG0477	Major facilitator Superfamily
AV941_RS18825	COG4319	ketosteroid isomerase
AV941_RS18850	COG2375	cellular response to nickel ion
AV941_RS18855	COG3237	CsbD-like
AV941_RS18890	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_RS18890	COG0596	Alpha beta hydrolase
AV941_RS18910	COG3038	cytochrome b561
AV941_RS18920	COG1252	NADH dehydrogenase
AV941_RS18935	COG0583	DNA-binding transcription factor activity
AV941_RS18940	COG2067	long-chain fatty acid transport protein
AV941_RS18945	COG2130	NADP-dependent
AV941_RS18950	COG2203	Gaf domain
AV941_RS18950	COG3706	GGDEF domain
AV941_RS18950	COG4251	negative regulation of phosphorylation
AV941_RS18950	COG5001	Diguanylate cyclase
AV941_RS18955	COG2205	protein histidine kinase activity
AV941_RS18955	COG0784	Response regulator, receiver
AV941_RS18965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_RS18970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV941_RS18975	COG1349	DNA-binding transcription factor activity
AV941_RS18980	COG0673	inositol 2-dehydrogenase activity
AV941_RS18995	COG0697	spore germination
AV941_RS19000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV941_RS19005	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AV941_RS19010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV941_RS19015	COG1166	arginine decarboxylase activity
AV941_RS19025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AV941_RS19105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_RS19110	COG0109	protoheme IX farnesyltransferase activity
AV941_RS19130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV941_RS19145	COG1487	ribonuclease activity
AV941_RS19175	COG3030	protein affecting phage T7 exclusion by the F plasmid
AV941_RS19180	COG1324	tolerance protein
AV941_RS19185	COG4232	protein-disulfide reductase activity
AV941_RS19190	COG0739	heme binding
AV941_RS19195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV941_RS19200	COG0511	ligase activity, forming carbon-carbon bonds
AV941_RS19205	COG0439	Biotin carboxylase
AV941_RS19250	COG0154	amidase activity
AV941_RS19265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_RS19270	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AV941_RS19285	COG0151	Belongs to the GarS family
AV941_RS19300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV941_RS19305	COG3954	Phosphoribulokinase
AV941_RS19330	COG1501	Belongs to the glycosyl hydrolase 31 family
AV941_RS19335	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AV941_RS19340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV941_RS19350	COG3031	protein transport across the cell outer membrane
AV941_RS19360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_RS19365	COG1459	type II secretion system
AV941_RS19370	COG2165	general secretion pathway protein
AV941_RS19375	COG2165	general secretion pathway protein
AV941_RS19380	COG2165	general secretion pathway protein
AV941_RS19385	COG4795	General secretion pathway protein
AV941_RS19400	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AV941_RS19415	COG1012	belongs to the aldehyde dehydrogenase family
AV941_RS19425	COG1011	Hydrolase
AV941_RS19430	COG0494	nUDIX hydrolase
AV941_RS19435	COG1218	3'(2'),5'-bisphosphate nucleotidase
AV941_RS19445	COG2943	transferase activity, transferring hexosyl groups
AV941_RS19450	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AV941_RS19460	COG3089	Belongs to the UPF0270 family
AV941_RS19465	COG0429	hydrolase of the alpha beta-hydrolase fold
AV941_RS19475	COG0488	(ABC) transporter
AV941_RS19495	COG2900	Belongs to the SlyX family
AV941_RS19505	COG0545	Peptidyl-prolyl cis-trans isomerase
AV941_RS19515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_RS19520	COG2183	response to ionizing radiation
AV941_RS19545	COG2207	Transcriptional regulator
AV941_RS19545	COG1609	Transcriptional regulator
AV941_RS19550	COG2211	Major facilitator Superfamily
AV941_RS19565	COG3693	PFAM glycoside hydrolase, family 10
AV941_RS19570	COG0667	Aldo Keto reductase
AV941_RS19575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV941_RS19580	COG2115	Belongs to the xylose isomerase family
AV941_RS19585	COG1070	Carbohydrate kinase
AV941_RS19600	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_RS19605	COG0477	Major facilitator Superfamily
AV941_RS19650	COG0596	Alpha beta hydrolase
AV941_RS19655	COG1040	competence protein
AV941_RS19670	COG1794	racemase activity, acting on amino acids and derivatives
AV941_RS19680	COG0534	Mate efflux family protein
AV941_RS19695	COG1999	signal sequence binding
AV941_RS19700	COG0109	protoheme IX farnesyltransferase activity
AV941_RS19705	COG1612	heme a metabolic process
AV941_RS19725	COG1845	cytochrome c oxidase, subunit III
AV941_RS19730	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AV941_RS19735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV941_RS19740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV941_RS19760	COG0129	dihydroxy-acid dehydratase activity
AV941_RS19770	COG0606	chelatase, subunit chli
AV941_RS19775	COG0583	DNA-binding transcription factor activity
AV941_RS19785	COG2814	Major facilitator Superfamily
AV941_RS19795	COG0729	surface antigen
AV941_RS19800	COG2911	Protein conserved in bacteria
AV941_RS19825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV941_RS19835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV941_RS19855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV941_RS19880	COG1228	amidohydrolase
AV941_RS19905	COG0425	Belongs to the sulfur carrier protein TusA family
AV941_RS19920	COG1561	YicC-like family, N-terminal region
AV941_RS19930	COG3550	peptidyl-serine autophosphorylation
AV941_RS19935	COG3620	sequence-specific DNA binding
AV941_RS20055	COG5433	transposase activity
AV941_RS20060	COG3119	arylsulfatase activity
AV941_RS20065	COG0714	Associated with various cellular activities
AV941_RS20085	COG2304	oxidoreductase activity
AV941_RS20115	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_RS20120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV941_RS20130	COG1960	acyl-CoA dehydrogenase activity
AV941_RS20140	COG1024	Enoyl-CoA hydratase
AV941_RS20160	COG0129	dihydroxy-acid dehydratase activity
AV941_RS20180	COG3177	Filamentation induced by cAMP protein fic
AV941_RS20190	COG1609	Transcriptional regulator
AV941_RS20205	COG2199	diguanylate cyclase activity
AV941_RS20205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AV941_RS20230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV941_RS20250	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV941_RS20255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV941_RS20275	COG1475	DNA binding
AV941_RS20280	COG1192	Involved in chromosome partitioning
AV941_RS20305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV941_RS20320	COG0706	membrane insertase activity
AV941_RS20325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AV941_RS20330	COG0594	ribonuclease P activity
AV941_RS20335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AV941_RS20855	COG1132	(ABC) transporter
AV941_RS20945	COG2201	protein-glutamate methylesterase activity
AV941_RS21000	COG5290	Psort location Cytoplasmic, score
AV941_RS21030	COG3209	COG3209 Rhs family protein
AV941_RS21040	COG3209	COG3209 Rhs family protein
AV941_RS21160	COG5310	Homospermidine synthase
AV941_RS21185	COG3251	PFAM MbtH domain protein
AV941_RS21345	COG0210	DNA helicase
AV941_RS21385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_RS21415	COG4584	PFAM Integrase catalytic
AV941_RS21420	COG1484	DNA-dependent DNA replication
AV941_RS21430	COG3300	MHYT domain
AV941_RS21430	COG5001	Diguanylate cyclase
AV941_RS21445	COG3706	GGDEF domain
AV941_RS21525	COG1192	Involved in chromosome partitioning