locus-tag	class	description
KUC3_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KUC3_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KUC3_RS00020	COG0187	DNA topoisomerase II activity
KUC3_RS00050	COG2818	Glycosylase
KUC3_RS00060	COG3078	GTPase activator activity
KUC3_RS00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC3_RS00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC3_RS00085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KUC3_RS00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC3_RS00095	COG0569	domain protein
KUC3_RS00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KUC3_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KUC3_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KUC3_RS00120	COG0758	DNA mediated transformation
KUC3_RS00135	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_RS00140	COG0408	coproporphyrinogen oxidase activity
KUC3_RS00145	COG3047	cAMP biosynthetic process
KUC3_RS00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KUC3_RS00225	COG2234	aminopeptidase activity
KUC3_RS00230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_RS00230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC3_RS00245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KUC3_RS00270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_RS00300	COG3642	lipopolysaccharide core region biosynthetic process
KUC3_RS00305	COG0859	PFAM glycosyl transferase family 9
KUC3_RS00335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC3_RS00350	COG3161	chorismate lyase activity
KUC3_RS00355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KUC3_RS00375	COG0210	DNA helicase
KUC3_RS00395	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS00435	COG1595	DNA-templated transcription, initiation
KUC3_RS00440	COG0318	PFAM AMP-dependent synthetase and ligase
KUC3_RS00460	COG1024	Enoyl-CoA hydratase
KUC3_RS00465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_RS00475	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS00485	COG4191	Histidine kinase
KUC3_RS00500	COG1136	(ABC) transporter
KUC3_RS00505	COG0577	efflux transmembrane transporter activity
KUC3_RS00510	COG3706	GGDEF domain
KUC3_RS00515	COG0745	RESPONSE REGULATOR receiver
KUC3_RS00520	COG2205	protein histidine kinase activity
KUC3_RS00530	COG0793	Belongs to the peptidase S41A family
KUC3_RS00540	COG4773	Receptor
KUC3_RS00550	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS00555	COG0583	DNA-binding transcription factor activity
KUC3_RS00565	COG3106	COG3106 Predicted ATPase
KUC3_RS00585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KUC3_RS00605	COG0352	thiamine-phosphate diphosphorylase activity
KUC3_RS00615	COG3071	HemY protein
KUC3_RS00620	COG2959	enzyme of heme biosynthesis
KUC3_RS00630	COG0181	hydroxymethylbilane synthase activity
KUC3_RS00645	COG0194	GDP metabolic process
KUC3_RS00655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC3_RS00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_RS00680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KUC3_RS00690	COG0678	peroxiredoxin activity
KUC3_RS00705	COG1178	ABC-type Fe3 transport system permease component
KUC3_RS00710	COG3842	ATPase activity
KUC3_RS00715	COG2081	HI0933 family
KUC3_RS00750	COG0583	DNA-binding transcription factor activity
KUC3_RS00770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS00785	COG0427	acetyl-CoA hydrolase
KUC3_RS00790	COG0123	including yeast histone deacetylase and acetoin utilization protein
KUC3_RS00805	COG0840	transmembrane signaling receptor activity
KUC3_RS00815	COG3064	Membrane
KUC3_RS00825	COG5001	Diguanylate cyclase
KUC3_RS00825	COG5002	protein histidine kinase activity
KUC3_RS00840	COG0514	ATP-dependent DNA helicase (RecQ)
KUC3_RS00845	COG2050	protein possibly involved in aromatic compounds catabolism
KUC3_RS00850	COG2239	Acts as a magnesium transporter
KUC3_RS00855	COG2962	Rard protein
KUC3_RS00865	COG0210	DNA helicase
KUC3_RS00880	COG1011	Hydrolase
KUC3_RS00885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KUC3_RS00895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KUC3_RS00900	COG0019	diaminopimelate decarboxylase activity
KUC3_RS00930	COG0163	prenyltransferase activity
KUC3_RS00935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC3_RS00945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KUC3_RS00960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC3_RS00985	COG1136	(ABC) transporter
KUC3_RS00985	COG0577	efflux transmembrane transporter activity
KUC3_RS00995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS01010	COG4555	ABC transporter
KUC3_RS01060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KUC3_RS01065	COG2814	Major facilitator Superfamily
KUC3_RS01070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KUC3_RS01095	COG1085	galactose-1-phosphate uridylyltransferase
KUC3_RS01100	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KUC3_RS01135	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS01160	COG1349	DNA-binding transcription factor activity
KUC3_RS01180	COG1077	Cell shape determining protein MreB Mrl
KUC3_RS01185	COG1792	Involved in formation and maintenance of cell shape
KUC3_RS01190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KUC3_RS01195	COG0424	maF-like protein
KUC3_RS01200	COG1530	ribonuclease E activity
KUC3_RS01210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_RS01215	COG0312	modulator of DNA gyrase
KUC3_RS01230	COG0784	Response regulator, receiver
KUC3_RS01230	COG2205	protein histidine kinase activity
KUC3_RS01235	COG3028	Belongs to the UPF0307 family
KUC3_RS01240	COG0312	modulator of DNA gyrase
KUC3_RS01245	COG2207	Transcriptional regulator
KUC3_RS01255	COG0745	RESPONSE REGULATOR receiver
KUC3_RS01260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS01260	COG4191	Histidine kinase
KUC3_RS01265	COG0297	glycogen (starch) synthase activity
KUC3_RS01275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KUC3_RS01305	COG0840	transmembrane signaling receptor activity
KUC3_RS01310	COG0745	RESPONSE REGULATOR receiver
KUC3_RS01315	COG2198	Histidine kinase
KUC3_RS01315	COG0643	Histidine kinase
KUC3_RS01320	COG0835	chemotaxis
KUC3_RS01355	COG1595	DNA-templated transcription, initiation
KUC3_RS01370	COG0784	Response regulator, receiver
KUC3_RS01370	COG2205	protein histidine kinase activity
KUC3_RS01395	COG0784	Response regulator, receiver
KUC3_RS01395	COG2205	protein histidine kinase activity
KUC3_RS01410	COG1609	Transcriptional regulator
KUC3_RS01415	COG0673	inositol 2-dehydrogenase activity
KUC3_RS01425	COG2211	Major facilitator Superfamily
KUC3_RS01430	COG1082	Xylose isomerase domain protein TIM barrel
KUC3_RS01450	COG1454	alcohol dehydrogenase
KUC3_RS01515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC3_RS01535	COG0089	rRNA binding
KUC3_RS01545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KUC3_RS01555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KUC3_RS01570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KUC3_RS01575	COG0297	glycogen (starch) synthase activity
KUC3_RS01585	COG1519	Transferase
KUC3_RS01605	COG0840	transmembrane signaling receptor activity
KUC3_RS01625	COG0788	formyltetrahydrofolate deformylase activity
KUC3_RS01635	COG1643	Atp-dependent helicase
KUC3_RS01640	COG2951	lytic endotransglycosylase activity
KUC3_RS01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KUC3_RS01655	COG2354	Protein conserved in bacteria
KUC3_RS01680	COG0004	ammonium transporteR
KUC3_RS01685	COG0405	Gamma-glutamyltransferase
KUC3_RS01690	COG2837	iron assimilation
KUC3_RS01700	COG0540	Belongs to the ATCase OTCase family
KUC3_RS01710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS01725	COG5002	protein histidine kinase activity
KUC3_RS01725	COG2205	protein histidine kinase activity
KUC3_RS01725	COG0784	Response regulator, receiver
KUC3_RS01740	COG5001	Diguanylate cyclase
KUC3_RS01740	COG3300	MHYT domain
KUC3_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KUC3_RS01775	COG0180	Tryptophanyl-tRNA synthetase
KUC3_RS01780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KUC3_RS01800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KUC3_RS01810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KUC3_RS01845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KUC3_RS01850	COG0281	malic enzyme
KUC3_RS01860	COG0625	glutathione transferase activity
KUC3_RS01885	COG5001	Diguanylate cyclase
KUC3_RS01885	COG3300	MHYT domain
KUC3_RS01890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KUC3_RS01890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KUC3_RS01900	COG0137	argininosuccinate synthase activity
KUC3_RS01905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KUC3_RS01920	COG1803	Methylglyoxal synthase
KUC3_RS01930	COG0745	RESPONSE REGULATOR receiver
KUC3_RS01935	COG2205	protein histidine kinase activity
KUC3_RS01940	COG2267	carboxylic ester hydrolase activity
KUC3_RS01945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KUC3_RS01950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KUC3_RS01960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC3_RS01965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC3_RS01970	COG4942	peptidase
KUC3_RS01975	COG2861	carbohydrate metabolic process
KUC3_RS01985	COG0584	glycerophosphoryl diester phosphodiesterase
KUC3_RS02000	COG1162	GTPase activity
KUC3_RS02005	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KUC3_RS02025	COG0457	Tetratricopeptide repeat
KUC3_RS02040	COG0028	Belongs to the TPP enzyme family
KUC3_RS02050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_RS02055	COG1288	antiporter activity
KUC3_RS02060	COG4206	TonB-dependent receptor
KUC3_RS02080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KUC3_RS02085	COG0805	protein transport
KUC3_RS02095	COG0084	hydrolase, TatD family'
KUC3_RS02100	COG4251	negative regulation of phosphorylation
KUC3_RS02100	COG3706	GGDEF domain
KUC3_RS02100	COG2203	Gaf domain
KUC3_RS02100	COG5001	Diguanylate cyclase
KUC3_RS02110	COG0248	Ppx GppA phosphatase
KUC3_RS02115	COG0513	Belongs to the DEAD box helicase family
KUC3_RS02120	COG3118	belongs to the thioredoxin family
KUC3_RS02125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KUC3_RS02130	COG1473	amidohydrolase
KUC3_RS02135	COG5002	protein histidine kinase activity
KUC3_RS02135	COG0784	Response regulator, receiver
KUC3_RS02140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KUC3_RS02145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KUC3_RS02150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KUC3_RS02165	COG0783	Belongs to the Dps family
KUC3_RS02170	COG2133	pyrroloquinoline quinone binding
KUC3_RS02175	COG1506	peptidase
KUC3_RS02175	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_RS02175	COG4946	Tricorn protease homolog
KUC3_RS02185	COG3118	belongs to the thioredoxin family
KUC3_RS02200	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KUC3_RS02210	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS02235	COG1757	Na H antiporter
KUC3_RS02250	COG3876	Protein conserved in bacteria
KUC3_RS02255	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KUC3_RS02275	COG0346	lactoylglutathione lyase activity
KUC3_RS02305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KUC3_RS02315	COG2824	Alkylphosphonate utilization operon protein PhnA
KUC3_RS02320	COG0454	-acetyltransferase
KUC3_RS02445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KUC3_RS02470	COG0183	Belongs to the thiolase family
KUC3_RS02475	COG1024	Enoyl-CoA hydratase
KUC3_RS02475	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC3_RS02480	COG0741	lytic transglycosylase activity
KUC3_RS02480	COG1196	nuclear chromosome segregation
KUC3_RS02480	COG0739	heme binding
KUC3_RS02485	COG0006	proline dipeptidase activity
KUC3_RS02495	COG0142	geranyltranstransferase activity
KUC3_RS02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC3_RS02525	COG1388	LysM domain
KUC3_RS02525	COG4942	peptidase
KUC3_RS02530	COG1238	metal cluster binding
KUC3_RS02540	COG0585	pseudouridine synthase activity
KUC3_RS02545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KUC3_RS02555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KUC3_RS02565	COG0840	transmembrane signaling receptor activity
KUC3_RS02570	COG1522	sequence-specific DNA binding
KUC3_RS02575	COG1063	alcohol dehydrogenase
KUC3_RS02605	COG0494	nUDIX hydrolase
KUC3_RS02610	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KUC3_RS02615	COG0730	response to heat
KUC3_RS02620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KUC3_RS02625	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KUC3_RS02635	COG3706	GGDEF domain
KUC3_RS02640	COG4999	Histidine kinase
KUC3_RS02640	COG3850	Histidine kinase
KUC3_RS02640	COG3437	response regulator, receiver
KUC3_RS02640	COG2205	protein histidine kinase activity
KUC3_RS02645	COG2211	Major facilitator Superfamily
KUC3_RS02660	COG0564	pseudouridine synthase activity
KUC3_RS02665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KUC3_RS02675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KUC3_RS02680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_RS02695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC3_RS02695	COG1648	precorrin-2 dehydrogenase activity
KUC3_RS02700	COG0513	Belongs to the DEAD box helicase family
KUC3_RS02720	COG1538	Outer membrane efflux protein
KUC3_RS02725	COG0494	nUDIX hydrolase
KUC3_RS02740	COG3150	esterase
KUC3_RS02770	COG1509	lysine 2,3-aminomutase activity
KUC3_RS02775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KUC3_RS02780	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KUC3_RS02800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC3_RS02820	COG0271	Belongs to the BolA IbaG family
KUC3_RS02825	COG0671	phosphoesterase, PA-phosphatase related
KUC3_RS02835	COG3707	response regulator
KUC3_RS02845	COG0659	secondary active sulfate transmembrane transporter activity
KUC3_RS02850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC3_RS02855	COG2146	nitrite reductase [NAD(P)H] activity
KUC3_RS02860	COG0243	molybdopterin cofactor binding
KUC3_RS02865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC3_RS02865	COG1648	precorrin-2 dehydrogenase activity
KUC3_RS02870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC3_RS02880	COG3706	GGDEF domain
KUC3_RS02890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUC3_RS02890	COG1116	anion transmembrane transporter activity
KUC3_RS02900	COG1116	anion transmembrane transporter activity
KUC3_RS02910	COG0746	molybdenum cofactor guanylyltransferase activity
KUC3_RS02920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC3_RS02925	COG4206	TonB-dependent receptor
KUC3_RS02930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KUC3_RS02935	COG0348	domain, Protein
KUC3_RS02950	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS02955	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS02960	COG3618	amidohydrolase
KUC3_RS02965	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_RS02985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS03005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC3_RS03010	COG0358	DNA primase activity
KUC3_RS03035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KUC3_RS03040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC3_RS03055	COG0537	adenosine 5'-monophosphoramidase activity
KUC3_RS03070	COG3135	benzoate transporter
KUC3_RS03075	COG1396	sequence-specific DNA binding
KUC3_RS03080	COG2974	May be involved in recombination
KUC3_RS03085	COG4191	Histidine kinase
KUC3_RS03085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS03090	COG0745	RESPONSE REGULATOR receiver
KUC3_RS03095	COG5002	protein histidine kinase activity
KUC3_RS03125	COG0811	peptide transport
KUC3_RS03130	COG0811	peptide transport
KUC3_RS03135	COG0848	biopolymer transport protein
KUC3_RS03140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC3_RS03150	COG3437	response regulator, receiver
KUC3_RS03155	COG5002	protein histidine kinase activity
KUC3_RS03155	COG2205	protein histidine kinase activity
KUC3_RS03155	COG0784	Response regulator, receiver
KUC3_RS03175	COG2133	pyrroloquinoline quinone binding
KUC3_RS03180	COG1049	propionate catabolic process, 2-methylcitrate cycle
KUC3_RS03190	COG3850	Histidine kinase
KUC3_RS03190	COG3437	response regulator, receiver
KUC3_RS03190	COG2205	protein histidine kinase activity
KUC3_RS03190	COG4999	Histidine kinase
KUC3_RS03195	COG2819	hydrolase of the alpha beta superfamily
KUC3_RS03205	COG1793	dna ligase
KUC3_RS03215	COG0527	aspartate kinase activity
KUC3_RS03220	COG3706	GGDEF domain
KUC3_RS03220	COG4251	negative regulation of phosphorylation
KUC3_RS03220	COG2203	Gaf domain
KUC3_RS03220	COG5001	Diguanylate cyclase
KUC3_RS03230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KUC3_RS03235	COG2967	ApaG domain
KUC3_RS03245	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KUC3_RS03250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_RS03255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KUC3_RS03260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KUC3_RS03270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC3_RS03275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KUC3_RS03290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KUC3_RS03305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC3_RS03310	COG3956	TIGRFAM MazG family protein
KUC3_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS03395	COG0642	Histidine kinase
KUC3_RS03415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KUC3_RS03420	COG0723	plastoquinol--plastocyanin reductase activity
KUC3_RS03425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KUC3_RS03430	COG2857	Cytochrome c1
KUC3_RS03435	COG0625	glutathione transferase activity
KUC3_RS03440	COG2969	positive regulation of protein catabolic process
KUC3_RS03455	COG0745	RESPONSE REGULATOR receiver
KUC3_RS03460	COG2239	Acts as a magnesium transporter
KUC3_RS03465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KUC3_RS03485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KUC3_RS03490	COG1137	ATPase activity
KUC3_RS03495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KUC3_RS03505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KUC3_RS03520	COG1127	ABC transporter
KUC3_RS03525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KUC3_RS03530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC3_RS03535	COG2854	intermembrane phospholipid transfer
KUC3_RS03545	COG5007	Belongs to the BolA IbaG family
KUC3_RS03555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC3_RS03560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC3_RS03570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KUC3_RS03595	COG0583	DNA-binding transcription factor activity
KUC3_RS03600	COG0384	phenazine biosynthesis protein PhzF
KUC3_RS03605	COG0583	DNA-binding transcription factor activity
KUC3_RS03610	COG1917	Cupin 2, conserved barrel domain protein
KUC3_RS03610	COG4977	sequence-specific DNA binding
KUC3_RS03615	COG2259	Doxx family
KUC3_RS03630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC3_RS03640	COG3220	belongs to the UPF0276 family
KUC3_RS03675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_RS03700	COG1162	GTPase activity
KUC3_RS03735	COG0745	RESPONSE REGULATOR receiver
KUC3_RS03745	COG0697	spore germination
KUC3_RS03755	COG2205	protein histidine kinase activity
KUC3_RS03755	COG0784	Response regulator, receiver
KUC3_RS03785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KUC3_RS03795	COG0126	phosphoglycerate kinase activity
KUC3_RS03800	COG3588	fructose-bisphosphate aldolase
KUC3_RS03820	COG0248	Ppx GppA phosphatase
KUC3_RS03825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KUC3_RS03835	COG0573	inorganic phosphate transmembrane transporter activity
KUC3_RS03845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KUC3_RS03855	COG0306	phosphate transporter
KUC3_RS03865	COG0583	DNA-binding transcription factor activity
KUC3_RS03890	COG1272	protein, Hemolysin III
KUC3_RS03895	COG1846	Transcriptional regulator
KUC3_RS03900	COG1764	response to oxidative stress
KUC3_RS03920	COG1739	Uncharacterized protein family UPF0029
KUC3_RS03935	COG0420	3'-5' exonuclease activity
KUC3_RS03940	COG0419	ATPase involved in DNA repair
KUC3_RS03955	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KUC3_RS03960	COG0010	Belongs to the arginase family
KUC3_RS03970	COG2188	Transcriptional regulator
KUC3_RS03975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KUC3_RS03980	COG2986	histidine ammonia-lyase
KUC3_RS04000	COG2971	BadF BadG BcrA BcrD
KUC3_RS04005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_RS04015	COG0488	(ABC) transporter
KUC3_RS04020	COG3002	Belongs to the UPF0753 family
KUC3_RS04025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KUC3_RS04030	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_RS04035	COG0583	DNA-binding transcription factor activity
KUC3_RS04055	COG0668	transmembrane transport
KUC3_RS04070	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_RS04075	COG0583	DNA-binding transcription factor activity
KUC3_RS04095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC3_RS04120	COG1858	cytochrome C peroxidase
KUC3_RS04150	COG1346	cytolysis
KUC3_RS04185	COG0583	DNA-binding transcription factor activity
KUC3_RS04190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KUC3_RS04200	COG0513	Belongs to the DEAD box helicase family
KUC3_RS04215	COG3655	Transcriptional regulator
KUC3_RS04230	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_RS04230	COG3267	Type II secretory pathway component ExeA
KUC3_RS04245	COG0066	3-isopropylmalate dehydratase activity
KUC3_RS04255	COG0473	3-isopropylmalate dehydrogenase activity
KUC3_RS04260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KUC3_RS04295	COG2271	Major facilitator Superfamily
KUC3_RS04305	COG0800	Aldolase
KUC3_RS04310	COG2186	Transcriptional regulator
KUC3_RS04345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KUC3_RS04360	COG4555	ABC transporter
KUC3_RS04365	COG1668	transmembrane transport
KUC3_RS04375	COG0745	RESPONSE REGULATOR receiver
KUC3_RS04410	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_RS04415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_RS04420	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_RS04430	COG1138	Cytochrome C-type biogenesis protein
KUC3_RS04450	COG2853	Lipoprotein
KUC3_RS04460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KUC3_RS04500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KUC3_RS04520	COG1555	photosystem II stabilization
KUC3_RS04525	COG0473	3-isopropylmalate dehydrogenase activity
KUC3_RS04540	COG1611	Belongs to the LOG family
KUC3_RS04590	COG0564	pseudouridine synthase activity
KUC3_RS04605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KUC3_RS04610	COG0024	Methionine aminopeptidase
KUC3_RS04615	COG0052	Belongs to the universal ribosomal protein uS2 family
KUC3_RS04625	COG0528	UMP kinase activity
KUC3_RS04635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KUC3_RS04640	COG0575	Belongs to the CDS family
KUC3_RS04645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KUC3_RS04650	COG0750	zinc metalloprotease
KUC3_RS04665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC3_RS04685	COG0587	DNA-directed DNA polymerase activity
KUC3_RS04690	COG0825	malonyl-CoA metabolic process
KUC3_RS04695	COG0037	tRNA processing
KUC3_RS04700	COG3706	GGDEF domain
KUC3_RS04725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KUC3_RS04725	COG0047	phosphoribosylformylglycinamidine synthase activity
KUC3_RS04735	COG2840	Smr protein MutS2
KUC3_RS04790	COG0784	Response regulator, receiver
KUC3_RS04790	COG0835	chemotaxis
KUC3_RS04795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KUC3_RS04800	COG1815	bacterial-type flagellum-dependent cell motility
KUC3_RS04810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KUC3_RS04815	COG1749	Flagellar hook protein flgE
KUC3_RS04820	COG4787	bacterial-type flagellum-dependent cell motility
KUC3_RS04840	COG3951	Flagellar rod assembly protein muramidase FlgJ
KUC3_RS04840	COG1705	Flagellar rod assembly protein muramidase FlgJ
KUC3_RS04845	COG1256	bacterial-type flagellum assembly
KUC3_RS04870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KUC3_RS04880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KUC3_RS04915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KUC3_RS04920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC3_RS04940	COG1215	transferase activity, transferring glycosyl groups
KUC3_RS04945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC3_RS04950	COG1086	Polysaccharide biosynthesis protein
KUC3_RS04965	COG3475	LICD family
KUC3_RS04970	COG2089	acid synthase
KUC3_RS04980	COG1083	cytidylyl-transferase
KUC3_RS04985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_RS05010	COG1677	Flagellar hook-basal body complex protein FliE
KUC3_RS05015	COG1766	The M ring may be actively involved in energy transduction
KUC3_RS05020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KUC3_RS05070	COG1987	bacterial-type flagellum assembly
KUC3_RS05085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KUC3_RS05110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KUC3_RS05115	COG0784	Response regulator, receiver
KUC3_RS05115	COG2198	Histidine kinase
KUC3_RS05115	COG0643	Histidine kinase
KUC3_RS05120	COG2201	protein-glutamate methylesterase activity
KUC3_RS05125	COG1192	Involved in chromosome partitioning
KUC3_RS05135	COG0835	chemotaxis
KUC3_RS05150	COG0646	methionine synthase
KUC3_RS05150	COG1410	methionine synthase
KUC3_RS05155	COG0646	methionine synthase
KUC3_RS05155	COG1410	methionine synthase
KUC3_RS05165	COG4269	membrane
KUC3_RS05180	COG0583	DNA-binding transcription factor activity
KUC3_RS05195	COG0659	secondary active sulfate transmembrane transporter activity
KUC3_RS05205	COG1309	transcriptional regulator
KUC3_RS05210	COG3590	peptidase
KUC3_RS05225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KUC3_RS05255	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KUC3_RS05260	COG4172	Belongs to the ABC transporter superfamily
KUC3_RS05270	COG4171	peptide transport system, permease
KUC3_RS05275	COG4168	peptide transport system, permease
KUC3_RS05280	COG0747	negative chemotaxis
KUC3_RS05285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KUC3_RS05290	COG1842	Phage shock protein A
KUC3_RS05320	COG0625	glutathione transferase activity
KUC3_RS05325	COG1522	sequence-specific DNA binding
KUC3_RS05375	COG0811	peptide transport
KUC3_RS05380	COG0811	peptide transport
KUC3_RS05385	COG0848	biopolymer transport protein
KUC3_RS05440	COG0456	acetyltransferase
KUC3_RS05450	COG0583	DNA-binding transcription factor activity
KUC3_RS05455	COG2814	Major facilitator Superfamily
KUC3_RS05460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUC3_RS05465	COG0656	L-ascorbic acid biosynthetic process
KUC3_RS05475	COG3706	GGDEF domain
KUC3_RS05495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_RS05500	COG3706	GGDEF domain
KUC3_RS05515	COG0583	DNA-binding transcription factor activity
KUC3_RS05520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KUC3_RS05535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC3_RS05560	COG0583	DNA-binding transcription factor activity
KUC3_RS05565	COG0702	epimerase
KUC3_RS05600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KUC3_RS05605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KUC3_RS05610	COG0564	pseudouridine synthase activity
KUC3_RS05620	COG0612	Peptidase, M16
KUC3_RS05625	COG2918	glutathione biosynthetic process
KUC3_RS05635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KUC3_RS05640	COG0784	Response regulator, receiver
KUC3_RS05640	COG5002	protein histidine kinase activity
KUC3_RS05650	COG1136	(ABC) transporter
KUC3_RS05655	COG1136	(ABC) transporter
KUC3_RS05655	COG0577	efflux transmembrane transporter activity
KUC3_RS05660	COG1136	(ABC) transporter
KUC3_RS05660	COG0577	efflux transmembrane transporter activity
KUC3_RS05675	COG0366	Alpha amylase catalytic
KUC3_RS05690	COG2840	Smr protein MutS2
KUC3_RS05695	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC3_RS05710	COG2719	SpoVR family
KUC3_RS05715	COG2718	Belongs to the UPF0229 family
KUC3_RS05720	COG2766	serine protein kinase
KUC3_RS05725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KUC3_RS05730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KUC3_RS05735	COG4771	TonB-dependent receptor
KUC3_RS05750	COG4206	TonB-dependent receptor
KUC3_RS05760	COG0450	alkyl hydroperoxide reductase
KUC3_RS05775	COG0584	glycerophosphoryl diester phosphodiesterase
KUC3_RS05780	COG0346	lactoylglutathione lyase activity
KUC3_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS05790	COG1278	Cold shock
KUC3_RS05805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KUC3_RS05810	COG4660	Part of a membrane complex involved in electron transport
KUC3_RS05815	COG4659	FMN binding
KUC3_RS05820	COG4658	electron transport chain
KUC3_RS05825	COG4656	Part of a membrane complex involved in electron transport
KUC3_RS05830	COG2878	Part of a membrane complex involved in electron transport
KUC3_RS05835	COG4657	Part of a membrane complex involved in electron transport
KUC3_RS05845	COG0534	Mate efflux family protein
KUC3_RS05850	COG0556	nucleotide-excision repair
KUC3_RS05875	COG0602	queuosine metabolic process
KUC3_RS05885	COG0367	asparagine synthase
KUC3_RS05910	COG3273	potassium ion transport
KUC3_RS05910	COG0471	metal ion transport
KUC3_RS05925	COG0529	Catalyzes the synthesis of activated sulfate
KUC3_RS05930	COG0175	sulfate reduction
KUC3_RS05935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS05965	COG2304	oxidoreductase activity
KUC3_RS05985	COG0714	Associated with various cellular activities
KUC3_RS05995	COG1024	Enoyl-CoA hydratase
KUC3_RS05995	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC3_RS06015	COG1025	Belongs to the peptidase M16 family
KUC3_RS06020	COG2062	phosphohistidine phosphatase, SixA
KUC3_RS06030	COG4536	flavin adenine dinucleotide binding
KUC3_RS06035	COG4137	Cytochrome C assembly protein
KUC3_RS06040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KUC3_RS06080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS06085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS06090	COG1132	(ABC) transporter
KUC3_RS06095	COG0228	four-way junction DNA binding
KUC3_RS06100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KUC3_RS06105	COG0336	Belongs to the RNA methyltransferase TrmD family
KUC3_RS06110	COG0335	large ribosomal subunit rRNA binding
KUC3_RS06115	COG2860	membrane
KUC3_RS06130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KUC3_RS06135	COG1605	Chorismate mutase
KUC3_RS06135	COG0287	Prephenate dehydrogenase
KUC3_RS06145	COG1605	Chorismate mutase
KUC3_RS06145	COG0077	Prephenate dehydratase
KUC3_RS06150	COG0745	RESPONSE REGULATOR receiver
KUC3_RS06155	COG0023	Translation Initiation Factor
KUC3_RS06165	COG0745	RESPONSE REGULATOR receiver
KUC3_RS06185	COG2205	protein histidine kinase activity
KUC3_RS06195	COG2204	response regulator
KUC3_RS06205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KUC3_RS06210	COG0494	nUDIX hydrolase
KUC3_RS06215	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KUC3_RS06220	COG0632	four-way junction helicase activity
KUC3_RS06225	COG2255	four-way junction helicase activity
KUC3_RS06230	COG0824	Thioesterase
KUC3_RS06235	COG0811	peptide transport
KUC3_RS06250	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_RS06255	COG2885	chlorophyll binding
KUC3_RS06260	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KUC3_RS06270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KUC3_RS06295	COG4319	ketosteroid isomerase
KUC3_RS06315	COG1725	Transcriptional regulator
KUC3_RS06375	COG3620	sequence-specific DNA binding
KUC3_RS06380	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC3_RS06390	COG0513	Belongs to the DEAD box helicase family
KUC3_RS06410	COG0583	DNA-binding transcription factor activity
KUC3_RS06420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS06430	COG1309	transcriptional regulator
KUC3_RS06435	COG4774	siderophore transport
KUC3_RS06455	COG3706	GGDEF domain
KUC3_RS06465	COG3008	intermembrane lipid transfer
KUC3_RS06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC3_RS06470	COG2995	paraquat-inducible protein a
KUC3_RS06480	COG0583	DNA-binding transcription factor activity
KUC3_RS06500	COG2207	Transcriptional regulator
KUC3_RS06505	COG0017	Asparaginyl-tRNA synthetase
KUC3_RS06520	COG0189	ligase activity
KUC3_RS06540	COG2201	protein-glutamate methylesterase activity
KUC3_RS06545	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KUC3_RS06575	COG0156	8-amino-7-oxononanoate synthase activity
KUC3_RS06590	COG3340	Belongs to the peptidase S51 family
KUC3_RS06595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KUC3_RS06600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KUC3_RS06605	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KUC3_RS06610	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KUC3_RS06640	COG2205	protein histidine kinase activity
KUC3_RS06645	COG0745	RESPONSE REGULATOR receiver
KUC3_RS06650	COG0569	domain protein
KUC3_RS06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC3_RS06665	COG5265	(ABC) transporter
KUC3_RS06670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KUC3_RS06680	COG0745	RESPONSE REGULATOR receiver
KUC3_RS06690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC3_RS06720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_RS06725	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_RS06730	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_RS06745	COG2755	lipolytic protein G-D-S-L family
KUC3_RS06750	COG4181	ATPase activity
KUC3_RS06755	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KUC3_RS06760	COG1090	epimerase
KUC3_RS06765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC3_RS06770	COG0628	permease
KUC3_RS06790	COG2350	Protein conserved in bacteria
KUC3_RS06795	COG0159	tryptophan synthase activity
KUC3_RS06805	COG0134	indole-3-glycerol-phosphate synthase activity
KUC3_RS06805	COG0135	phosphoribosylanthranilate isomerase activity
KUC3_RS06810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC3_RS06820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KUC3_RS06825	COG0613	PHP domain protein
KUC3_RS06830	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_RS06840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KUC3_RS06855	COG0656	L-ascorbic acid biosynthetic process
KUC3_RS06860	COG2188	Transcriptional regulator
KUC3_RS06865	COG1131	(ABC) transporter
KUC3_RS06875	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_RS06875	COG1506	peptidase
KUC3_RS06880	COG0110	maltose O-acetyltransferase activity
KUC3_RS06890	COG2733	membrane
KUC3_RS06910	COG0500	methyltransferase
KUC3_RS06915	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_RS06920	COG0497	DNA recombination
KUC3_RS06925	COG0783	Belongs to the Dps family
KUC3_RS06930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KUC3_RS06940	COG1454	alcohol dehydrogenase
KUC3_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS06955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUC3_RS06960	COG2610	gluconate transmembrane transporter activity
KUC3_RS06975	COG2205	protein histidine kinase activity
KUC3_RS06975	COG0784	Response regulator, receiver
KUC3_RS06980	COG2199	diguanylate cyclase activity
KUC3_RS06985	COG2205	protein histidine kinase activity
KUC3_RS06985	COG0784	Response regulator, receiver
KUC3_RS06990	COG1620	l-lactate permease
KUC3_RS06995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KUC3_RS07005	COG0484	heat shock protein binding
KUC3_RS07010	COG3909	cytochrome
KUC3_RS07020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KUC3_RS07045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KUC3_RS07055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KUC3_RS07060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC3_RS07065	COG0840	transmembrane signaling receptor activity
KUC3_RS07095	COG0280	phosphate acetyltransferase
KUC3_RS07095	COG0857	belongs to the CobB CobQ family
KUC3_RS07100	COG1228	amidohydrolase
KUC3_RS07105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KUC3_RS07110	COG4535	Mg2 and Co2 transporter CorC
KUC3_RS07120	COG1702	phosphate starvation-inducible protein PhoH
KUC3_RS07130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_RS07140	COG3706	GGDEF domain
KUC3_RS07145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS07150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS07195	COG1607	acyl-coa hydrolase
KUC3_RS07200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUC3_RS07205	COG1733	regulation of RNA biosynthetic process
KUC3_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS07220	COG1115	amino acid carrier protein
KUC3_RS07245	COG0012	GTP binding
KUC3_RS07270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KUC3_RS07280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KUC3_RS07285	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KUC3_RS07290	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KUC3_RS07300	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC3_RS07305	COG0784	Response regulator, receiver
KUC3_RS07305	COG3437	response regulator, receiver
KUC3_RS07315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KUC3_RS07325	COG0583	DNA-binding transcription factor activity
KUC3_RS07335	COG2363	Small membrane protein
KUC3_RS07355	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_RS07355	COG0793	Belongs to the peptidase S41A family
KUC3_RS07360	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KUC3_RS07370	COG2116	formate transmembrane transporter activity
KUC3_RS07385	COG0714	Associated with various cellular activities
KUC3_RS07390	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KUC3_RS07395	COG0033	Phosphoglucomutase
KUC3_RS07400	COG0058	SHG alpha-glucan phosphorylase activity
KUC3_RS07405	COG5001	Diguanylate cyclase
KUC3_RS07405	COG3300	MHYT domain
KUC3_RS07410	COG2988	succinylglutamate desuccinylase activity
KUC3_RS07430	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC3_RS07450	COG1393	Belongs to the ArsC family
KUC3_RS07475	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KUC3_RS07495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC3_RS07510	COG3268	Saccharopine dehydrogenase
KUC3_RS07520	COG5001	Diguanylate cyclase
KUC3_RS07520	COG3300	MHYT domain
KUC3_RS07530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC3_RS07540	COG1309	transcriptional regulator
KUC3_RS07590	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_RS07615	COG1733	regulation of RNA biosynthetic process
KUC3_RS07625	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_RS07630	COG3706	GGDEF domain
KUC3_RS07640	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_RS07645	COG2351	hydroxyisourate hydrolase activity
KUC3_RS07660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KUC3_RS07670	COG1309	transcriptional regulator
KUC3_RS07685	COG2252	PERMEase
KUC3_RS07690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KUC3_RS07710	COG0784	Response regulator, receiver
KUC3_RS07710	COG2205	protein histidine kinase activity
KUC3_RS07725	COG2233	PERMEase
KUC3_RS07740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC3_RS07745	COG0730	response to heat
KUC3_RS07755	COG0154	amidase activity
KUC3_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS07790	COG3001	Fructosamine kinase
KUC3_RS07800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KUC3_RS07820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC3_RS07835	COG0489	protein tyrosine kinase activity
KUC3_RS07840	COG4464	protein tyrosine phosphatase activity
KUC3_RS07865	COG5001	Diguanylate cyclase
KUC3_RS07920	COG0463	Glycosyl transferase, family 2
KUC3_RS07935	COG0072	phenylalanine-tRNA ligase activity
KUC3_RS07935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_RS07965	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC3_RS07975	COG2096	Adenosyltransferase
KUC3_RS07985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KUC3_RS07995	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC3_RS08000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC3_RS08020	COG0708	Exodeoxyribonuclease III
KUC3_RS08080	COG2814	Major facilitator Superfamily
KUC3_RS08115	COG4770	biotin carboxylase activity
KUC3_RS08125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_RS08130	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS08135	COG0789	Transcriptional regulator
KUC3_RS08140	COG0183	Belongs to the thiolase family
KUC3_RS08165	COG2925	Exonuclease
KUC3_RS08190	COG1643	Atp-dependent helicase
KUC3_RS08210	COG0604	alcohol dehydrogenase
KUC3_RS08210	COG3321	synthase
KUC3_RS08215	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_RS08220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUC3_RS08235	COG1136	(ABC) transporter
KUC3_RS08240	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC3_RS08245	COG1301	dicarboxylic acid transport
KUC3_RS08255	COG3724	N-succinylarginine dihydrolase activity
KUC3_RS08260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KUC3_RS08265	COG3122	Protein conserved in bacteria
KUC3_RS08280	COG1609	Transcriptional regulator
KUC3_RS08300	COG0800	Aldolase
KUC3_RS08305	COG2271	Major facilitator Superfamily
KUC3_RS08310	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_RS08320	COG5285	phytanoyl-CoA dioxygenase
KUC3_RS08400	COG2124	cytochrome p450
KUC3_RS08420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KUC3_RS08425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KUC3_RS08430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KUC3_RS08435	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS08445	COG1063	alcohol dehydrogenase
KUC3_RS08450	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_RS08460	COG3386	PFAM SMP-30 Gluconolaconase
KUC3_RS08465	COG2814	Major facilitator Superfamily
KUC3_RS08470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_RS08485	COG0625	glutathione transferase activity
KUC3_RS08500	COG0826	peptidase U32
KUC3_RS08505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KUC3_RS08510	COG2153	protein acetylation
KUC3_RS08540	COG5002	protein histidine kinase activity
KUC3_RS08550	COG1530	ribonuclease E activity
KUC3_RS08555	COG0564	pseudouridine synthase activity
KUC3_RS08560	COG0546	phosphoglycolate phosphatase activity
KUC3_RS08565	COG0424	maF-like protein
KUC3_RS08570	COG1399	metal-binding, possibly nucleic acid-binding protein
KUC3_RS08580	COG0416	fatty acid biosynthetic process
KUC3_RS08585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KUC3_RS08590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KUC3_RS08600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KUC3_RS08605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC3_RS08615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KUC3_RS08630	COG0084	hydrolase, TatD family'
KUC3_RS08635	COG0259	pyridoxamine-phosphate oxidase activity
KUC3_RS08640	COG0702	epimerase
KUC3_RS08665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC3_RS08670	COG1609	Transcriptional regulator
KUC3_RS08700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS08710	COG4771	TonB-dependent receptor
KUC3_RS08745	COG3012	SEC-C Motif Domain Protein
KUC3_RS08755	COG1238	metal cluster binding
KUC3_RS08775	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KUC3_RS08780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC3_RS08785	COG0436	Aminotransferase
KUC3_RS08800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS08810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_RS08815	COG1765	OsmC-like protein
KUC3_RS08820	COG2996	Protein conserved in bacteria
KUC3_RS08830	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KUC3_RS08835	COG1984	allophanate hydrolase subunit 2
KUC3_RS08845	COG0735	belongs to the Fur family
KUC3_RS08855	COG0716	FMN binding
KUC3_RS08865	COG0596	Alpha beta hydrolase
KUC3_RS08920	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS08935	COG1671	Belongs to the UPF0178 family
KUC3_RS08945	COG0840	transmembrane signaling receptor activity
KUC3_RS08955	COG1448	Aminotransferase
KUC3_RS09000	COG1024	Enoyl-CoA hydratase
KUC3_RS09005	COG0405	Gamma-glutamyltransferase
KUC3_RS09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC3_RS09195	COG0534	Mate efflux family protein
KUC3_RS09200	COG0303	'Molybdopterin
KUC3_RS09210	COG0366	Alpha amylase catalytic
KUC3_RS09215	COG1215	transferase activity, transferring glycosyl groups
KUC3_RS09220	COG3769	mannosylglycerate metabolic process
KUC3_RS09225	COG0572	uridine kinase
KUC3_RS09255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KUC3_RS09290	COG1393	Belongs to the ArsC family
KUC3_RS09300	COG4783	chaperone-mediated protein folding
KUC3_RS09310	COG0583	DNA-binding transcription factor activity
KUC3_RS09325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KUC3_RS09335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC3_RS09340	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KUC3_RS09370	COG3239	Fatty acid desaturase
KUC3_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS09385	COG0583	DNA-binding transcription factor activity
KUC3_RS09395	COG0633	Ferredoxin
KUC3_RS09400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC3_RS09405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC3_RS09410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_RS09420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KUC3_RS09425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KUC3_RS09430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KUC3_RS09435	COG0539	negative regulation of cytoplasmic translation
KUC3_RS09440	COG0776	regulation of translation
KUC3_RS09450	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KUC3_RS09455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KUC3_RS09460	COG0284	orotidine-5'-phosphate decarboxylase activity
KUC3_RS09465	COG0686	Belongs to the AlaDH PNT family
KUC3_RS09475	COG0531	amino acid
KUC3_RS09475	COG1674	ftsk spoiiie
KUC3_RS09480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KUC3_RS09485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KUC3_RS09530	COG2920	part of a sulfur-relay system
KUC3_RS09545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KUC3_RS09550	COG0670	Belongs to the BI1 family
KUC3_RS09575	COG0583	DNA-binding transcription factor activity
KUC3_RS09580	COG2259	Doxx family
KUC3_RS09585	COG3384	dioxygenase
KUC3_RS09595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KUC3_RS09605	COG1741	Belongs to the pirin family
KUC3_RS09610	COG2197	response regulator
KUC3_RS09615	COG0322	excinuclease ABC activity
KUC3_RS09650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KUC3_RS09655	COG3148	PFAM DTW domain containing protein
KUC3_RS09660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KUC3_RS09665	COG2897	thiosulfate sulfurtransferase activity
KUC3_RS09675	COG1280	lysine exporter protein (LysE YggA)
KUC3_RS09695	COG1752	Esterase of the alpha-beta hydrolase superfamily
KUC3_RS09700	COG0037	tRNA processing
KUC3_RS09705	COG0589	response to stress
KUC3_RS09725	COG2217	Heavy metal translocating P-type atpase
KUC3_RS09735	COG2010	Cytochrome c
KUC3_RS09750	COG3278	Belongs to the heme-copper respiratory oxidase family
KUC3_RS09760	COG2193	ferroxidase activity
KUC3_RS09775	COG0069	glutamate synthase activity
KUC3_RS09785	COG0589	response to stress
KUC3_RS09790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KUC3_RS09800	COG4974	Belongs to the 'phage' integrase family
KUC3_RS09845	COG1082	Xylose isomerase domain protein TIM barrel
KUC3_RS09870	COG0534	Mate efflux family protein
KUC3_RS09885	COG3046	protein related to deoxyribodipyrimidine photolyase
KUC3_RS09890	COG0415	Belongs to the DNA photolyase family
KUC3_RS09895	COG0415	Belongs to the DNA photolyase family
KUC3_RS09900	COG0415	Belongs to the DNA photolyase family
KUC3_RS09910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC3_RS09915	COG3130	regulation of translation
KUC3_RS09925	COG0488	(ABC) transporter
KUC3_RS09940	COG0167	dihydroorotate dehydrogenase activity
KUC3_RS09945	COG2902	Dehydrogenase
KUC3_RS09975	COG0308	aminopeptidase N
KUC3_RS09980	COG1757	Na H antiporter
KUC3_RS09985	COG0733	neurotransmitter:sodium symporter activity
KUC3_RS09990	COG0793	Belongs to the peptidase S41A family
KUC3_RS10005	COG1956	GAF domain-containing protein
KUC3_RS10015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC3_RS10025	COG1946	Acyl-CoA thioesterase
KUC3_RS10035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KUC3_RS10045	COG0022	dehydrogenase e1 component
KUC3_RS10050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KUC3_RS10055	COG1404	Belongs to the peptidase S8 family
KUC3_RS10060	COG1322	Protein conserved in bacteria
KUC3_RS10075	COG0494	nUDIX hydrolase
KUC3_RS10080	COG1760	l-serine dehydratase
KUC3_RS10105	COG0583	DNA-binding transcription factor activity
KUC3_RS10110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUC3_RS10115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUC3_RS10120	COG0513	Belongs to the DEAD box helicase family
KUC3_RS10130	COG1054	Belongs to the UPF0176 family
KUC3_RS10140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS10140	COG2205	protein histidine kinase activity
KUC3_RS10145	COG2207	Transcriptional regulator
KUC3_RS10150	COG1073	alpha beta
KUC3_RS10160	COG0205	6-phosphofructokinase activity
KUC3_RS10170	COG3279	Response regulator of the LytR AlgR family
KUC3_RS10175	COG3275	phosphorelay sensor kinase activity
KUC3_RS10205	COG3081	Nucleoid-associated protein
KUC3_RS10210	COG3082	Protein of unknown function (DUF1414)
KUC3_RS10215	COG3083	sulfuric ester hydrolase activity
KUC3_RS10220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC3_RS10225	COG2226	methyltransferase
KUC3_RS10230	COG1024	Enoyl-CoA hydratase
KUC3_RS10235	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS10245	COG2084	Dehydrogenase
KUC3_RS10250	COG0386	Belongs to the glutathione peroxidase family
KUC3_RS10255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC3_RS10260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_RS10265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KUC3_RS10280	COG0616	signal peptide processing
KUC3_RS10290	COG2267	carboxylic ester hydrolase activity
KUC3_RS10295	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS10305	COG1609	Transcriptional regulator
KUC3_RS10320	COG0366	Alpha amylase catalytic
KUC3_RS10345	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC3_RS10400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_RS10405	COG0567	Dehydrogenase, E1 component
KUC3_RS10410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KUC3_RS10415	COG1053	succinate dehydrogenase
KUC3_RS10420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KUC3_RS10430	COG0372	Belongs to the citrate synthase family
KUC3_RS10450	COG0435	Glutathione S-transferase
KUC3_RS10455	COG0579	oxidoreductase
KUC3_RS10460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KUC3_RS10500	COG1663	tetraacyldisaccharide 4'-kinase activity
KUC3_RS10505	COG1132	(ABC) transporter
KUC3_RS10510	COG0658	competence protein
KUC3_RS10510	COG2333	competence protein COMEC
KUC3_RS10520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KUC3_RS10530	COG1196	nuclear chromosome segregation
KUC3_RS10535	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KUC3_RS10620	COG2226	methyltransferase
KUC3_RS10705	COG1185	polyribonucleotide nucleotidyltransferase activity
KUC3_RS10720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KUC3_RS10725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC3_RS10730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS10745	COG0561	phosphatase activity
KUC3_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS10760	COG1803	Methylglyoxal synthase
KUC3_RS10760	COG1597	lipid kinase activity
KUC3_RS10765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KUC3_RS10785	COG3706	GGDEF domain
KUC3_RS10795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC3_RS10800	COG0149	triose-phosphate isomerase activity
KUC3_RS10805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KUC3_RS10810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KUC3_RS10815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC3_RS10820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KUC3_RS10825	COG1534	Rna-binding protein
KUC3_RS10840	COG1067	ATP-dependent peptidase activity
KUC3_RS10850	COG0495	leucyl-tRNA aminoacylation
KUC3_RS10855	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KUC3_RS10860	COG1466	dna polymerase III delta subunit
KUC3_RS10865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KUC3_RS10870	COG0799	negative regulation of ribosome biogenesis
KUC3_RS10875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KUC3_RS10880	COG0768	penicillin binding
KUC3_RS10885	COG0772	Belongs to the SEDS family
KUC3_RS10890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC3_RS10895	COG1686	Belongs to the peptidase S11 family
KUC3_RS10900	COG2921	Belongs to the UPF0250 family
KUC3_RS10905	COG0321	lipoyl(octanoyl) transferase activity
KUC3_RS10910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KUC3_RS10915	COG0252	asparaginase activity
KUC3_RS10935	COG0778	Nitroreductase
KUC3_RS10950	COG0616	signal peptide processing
KUC3_RS10960	COG3092	negative regulation of chromosome organization
KUC3_RS10965	COG0492	ferredoxin-NADP+ reductase activity
KUC3_RS10970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KUC3_RS10975	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KUC3_RS10980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KUC3_RS10985	COG0542	response to heat
KUC3_RS10990	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KUC3_RS10995	COG1278	Cold shock
KUC3_RS11005	COG1187	pseudouridine synthase activity
KUC3_RS11010	COG0482	sulfurtransferase activity
KUC3_RS11015	COG2915	High frequency lysogenization protein hflD homolog
KUC3_RS11020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KUC3_RS11030	COG2850	peptidyl-arginine hydroxylation
KUC3_RS11065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KUC3_RS11065	COG0574	Belongs to the PEP-utilizing enzyme family
KUC3_RS11080	COG0457	Tetratricopeptide repeat
KUC3_RS11090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUC3_RS11100	COG2914	Belongs to the UPF0125 (RnfH) family
KUC3_RS11105	COG2867	negative regulation of translational initiation
KUC3_RS11115	COG1902	pentaerythritol trinitrate reductase activity
KUC3_RS11125	COG3706	GGDEF domain
KUC3_RS11135	COG1131	(ABC) transporter
KUC3_RS11165	COG0583	DNA-binding transcription factor activity
KUC3_RS11205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KUC3_RS11210	COG4136	ATPase activity
KUC3_RS11215	COG4135	transport system, permease component
KUC3_RS11220	COG4134	Bacterial extracellular solute-binding protein
KUC3_RS11230	COG4771	TonB-dependent receptor
KUC3_RS11245	COG1032	radical SAM domain protein
KUC3_RS11315	COG3153	acetyltransferase
KUC3_RS11315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_RS11345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KUC3_RS11360	COG0195	Participates in both transcription termination and antitermination
KUC3_RS11370	COG3437	response regulator, receiver
KUC3_RS11375	COG0784	Response regulator, receiver
KUC3_RS11375	COG2198	Histidine kinase
KUC3_RS11375	COG2205	protein histidine kinase activity
KUC3_RS11400	COG2205	protein histidine kinase activity
KUC3_RS11405	COG0745	RESPONSE REGULATOR receiver
KUC3_RS11420	COG4771	TonB-dependent receptor
KUC3_RS11425	COG0668	transmembrane transport
KUC3_RS11520	COG0596	Alpha beta hydrolase
KUC3_RS11525	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS11530	COG0183	Belongs to the thiolase family
KUC3_RS11540	COG0596	Alpha beta hydrolase
KUC3_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS11560	COG0366	Alpha amylase catalytic
KUC3_RS11565	COG0604	alcohol dehydrogenase
KUC3_RS11585	COG4771	TonB-dependent receptor
KUC3_RS11610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC3_RS11630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KUC3_RS11635	COG0315	cyclic pyranopterin monophosphate synthase activity
KUC3_RS11640	COG0521	Mo-molybdopterin cofactor biosynthetic process
KUC3_RS11645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KUC3_RS11665	COG0436	Aminotransferase
KUC3_RS11670	COG3268	Saccharopine dehydrogenase
KUC3_RS11680	COG1017	nitric oxide dioxygenase activity
KUC3_RS11680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUC3_RS11690	COG3604	Transcriptional regulator
KUC3_RS11715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_RS11730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KUC3_RS11735	COG1074	ATP-dependent DNA helicase activity
KUC3_RS11740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KUC3_RS11750	COG1022	Amp-dependent synthetase and ligase
KUC3_RS11755	COG5001	Diguanylate cyclase
KUC3_RS11755	COG3300	MHYT domain
KUC3_RS11775	COG0583	DNA-binding transcription factor activity
KUC3_RS11795	COG0640	Transcriptional regulator
KUC3_RS11805	COG0583	DNA-binding transcription factor activity
KUC3_RS11810	COG3932	Exopolysaccharide synthesis, ExoD
KUC3_RS11815	COG2204	response regulator
KUC3_RS11825	COG4251	negative regulation of phosphorylation
KUC3_RS11830	COG0784	Response regulator, receiver
KUC3_RS11835	COG2205	protein histidine kinase activity
KUC3_RS11835	COG0784	Response regulator, receiver
KUC3_RS11865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC3_RS11890	COG3139	Protein of unknown function (DUF1315)
KUC3_RS11900	COG1115	amino acid carrier protein
KUC3_RS11905	COG2866	Carboxypeptidase
KUC3_RS11925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KUC3_RS11935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KUC3_RS11940	COG1640	4-alpha-glucanotransferase
KUC3_RS11950	COG0676	glucose-6-phosphate 1-epimerase activity
KUC3_RS11955	COG0800	Aldolase
KUC3_RS11965	COG0129	dihydroxy-acid dehydratase activity
KUC3_RS11975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KUC3_RS11980	COG1737	Transcriptional regulator
KUC3_RS11985	COG0469	pyruvate kinase activity
KUC3_RS12015	COG2205	protein histidine kinase activity
KUC3_RS12015	COG0784	Response regulator, receiver
KUC3_RS12030	COG2356	endonuclease I
KUC3_RS12060	COG0583	DNA-binding transcription factor activity
KUC3_RS12070	COG1979	alcohol dehydrogenase
KUC3_RS12075	COG5001	Diguanylate cyclase
KUC3_RS12085	COG0753	catalase activity
KUC3_RS12090	COG0784	Response regulator, receiver
KUC3_RS12090	COG3437	response regulator, receiver
KUC3_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS12095	COG4191	Histidine kinase
KUC3_RS12130	COG0778	Nitroreductase
KUC3_RS12150	COG0330	HflC and HflK could
KUC3_RS12180	COG0431	NADPH-dependent FMN reductase
KUC3_RS12185	COG1741	Belongs to the pirin family
KUC3_RS12190	COG0583	DNA-binding transcription factor activity
KUC3_RS12210	COG0471	metal ion transport
KUC3_RS12225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_RS12225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_RS12230	COG2226	methyltransferase
KUC3_RS12235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_RS12240	COG0741	lytic transglycosylase activity
KUC3_RS12240	COG1388	LysM domain
KUC3_RS12260	COG0215	cysteine-tRNA ligase activity
KUC3_RS12265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC3_RS12270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC3_RS12275	COG1785	Belongs to the alkaline phosphatase family
KUC3_RS12280	COG1785	Belongs to the alkaline phosphatase family
KUC3_RS12295	COG2268	Band 7 protein
KUC3_RS12305	COG1136	(ABC) transporter
KUC3_RS12325	COG2205	protein histidine kinase activity
KUC3_RS12355	COG0604	alcohol dehydrogenase
KUC3_RS12360	COG0583	DNA-binding transcription factor activity
KUC3_RS12390	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KUC3_RS12395	COG1286	toxin biosynthetic process
KUC3_RS12400	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KUC3_RS12405	COG0285	dihydrofolate synthase activity
KUC3_RS12420	COG0101	tRNA pseudouridine synthase activity
KUC3_RS12435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC3_RS12450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC3_RS12460	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KUC3_RS12460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC3_RS12480	COG1119	ATPase activity
KUC3_RS12485	COG0612	Peptidase, M16
KUC3_RS12495	COG2031	fatty acid transporter
KUC3_RS12510	COG3101	peptidyl-lysine hydroxylation
KUC3_RS12550	COG3119	arylsulfatase activity
KUC3_RS12590	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_RS12600	COG3119	arylsulfatase activity
KUC3_RS12605	COG3119	arylsulfatase activity
KUC3_RS12610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_RS12615	COG0800	Aldolase
KUC3_RS12625	COG2814	Major facilitator Superfamily
KUC3_RS12630	COG1609	Transcriptional regulator
KUC3_RS12650	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_RS12650	COG1902	pentaerythritol trinitrate reductase activity
KUC3_RS12675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUC3_RS12685	COG4399	Belongs to the UPF0754 family
KUC3_RS12715	COG2186	Transcriptional regulator
KUC3_RS12725	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KUC3_RS12730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KUC3_RS12735	COG2983	Belongs to the UPF0260 family
KUC3_RS12740	COG0179	Fumarylacetoacetate (FAA) hydrolase
KUC3_RS12755	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KUC3_RS12765	COG2267	carboxylic ester hydrolase activity
KUC3_RS12780	COG1214	PFAM Peptidase M22, glycoprotease
KUC3_RS12785	COG1199	ATP-dependent helicase activity
KUC3_RS12800	COG0671	phosphoesterase, PA-phosphatase related
KUC3_RS12835	COG1192	Involved in chromosome partitioning
KUC3_RS12845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KUC3_RS12850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC3_RS12855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC3_RS12860	COG0131	Imidazoleglycerol-phosphate dehydratase
KUC3_RS12860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC3_RS12865	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KUC3_RS12885	COG0583	DNA-binding transcription factor activity
KUC3_RS12890	COG0612	Peptidase, M16
KUC3_RS12895	COG0681	Belongs to the peptidase S26 family
KUC3_RS12915	COG0326	Molecular chaperone. Has ATPase activity
KUC3_RS12920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KUC3_RS12940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KUC3_RS12945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC3_RS12955	COG3220	belongs to the UPF0276 family
KUC3_RS12995	COG1183	phosphatidylcholine synthase activity
KUC3_RS13010	COG0457	Tetratricopeptide repeat
KUC3_RS13015	COG0277	FAD linked oxidase domain protein
KUC3_RS13020	COG0542	response to heat
KUC3_RS13035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_RS13045	COG1595	DNA-templated transcription, initiation
KUC3_RS13060	COG4221	oxidoreductase activity
KUC3_RS13065	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KUC3_RS13075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KUC3_RS13085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KUC3_RS13095	COG0142	geranyltranstransferase activity
KUC3_RS13105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KUC3_RS13110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KUC3_RS13120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KUC3_RS13135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC3_RS13135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC3_RS13150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC3_RS13155	COG0488	(ABC) transporter
KUC3_RS13165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KUC3_RS13175	COG0560	Phosphoserine phosphatase
KUC3_RS13185	COG0084	hydrolase, TatD family'
KUC3_RS13200	COG0571	ribonuclease III activity
KUC3_RS13220	COG3026	antisigma factor binding
KUC3_RS13230	COG1595	DNA-templated transcription, initiation
KUC3_RS13235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KUC3_RS13250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KUC3_RS13260	COG1047	Peptidyl-prolyl cis-trans
KUC3_RS13330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KUC3_RS13335	COG1047	Peptidyl-prolyl cis-trans
KUC3_RS13345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KUC3_RS13350	COG0196	riboflavin kinase activity
KUC3_RS13355	COG0728	peptidoglycan biosynthetic process
KUC3_RS13360	COG0268	Binds directly to 16S ribosomal RNA
KUC3_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_RS13380	COG0385	Bile acid
KUC3_RS13415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_RS13420	COG0776	regulation of translation
KUC3_RS13425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KUC3_RS13435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KUC3_RS13440	COG0740	serine-type endopeptidase activity
KUC3_RS13445	COG0544	peptidyl-prolyl cis-trans isomerase activity
KUC3_RS13465	COG1720	tRNA m6t6A37 methyltransferase activity
KUC3_RS13475	COG1234	tRNA 3'-trailer cleavage
KUC3_RS13495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KUC3_RS13500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KUC3_RS13515	COG1858	cytochrome C peroxidase
KUC3_RS13535	COG0516	GMP reductase activity
KUC3_RS13535	COG0517	IMP dehydrogenase activity
KUC3_RS13540	COG1570	exodeoxyribonuclease VII activity
KUC3_RS13565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_RS13570	COG2976	Protein conserved in bacteria
KUC3_RS13590	COG3063	Type IV pilus biogenesis stability protein PilW
KUC3_RS13595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KUC3_RS13605	COG2166	iron-sulfur cluster assembly
KUC3_RS13620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC3_RS13625	COG0719	Fe-S assembly protein
KUC3_RS13630	COG0396	ATPase activity
KUC3_RS13635	COG0719	Fe-S assembly protein
KUC3_RS13640	COG1104	cysteine desulfurase activity
KUC3_RS13645	COG1959	2 iron, 2 sulfur cluster binding
KUC3_RS13650	COG1045	serine acetyltransferase
KUC3_RS13655	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KUC3_RS13660	COG0483	inositol monophosphate 1-phosphatase activity
KUC3_RS13675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_RS13680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_RS13685	COG1862	Preprotein translocase
KUC3_RS13690	COG0343	queuine tRNA-ribosyltransferase activity
KUC3_RS13710	COG1842	Phage shock protein A
KUC3_RS13715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUC3_RS13735	COG0754	glutathionylspermidine amidase activity
KUC3_RS13750	COG1136	(ABC) transporter
KUC3_RS13765	COG2066	Belongs to the glutaminase family
KUC3_RS13770	COG1785	Belongs to the alkaline phosphatase family
KUC3_RS13775	COG0745	RESPONSE REGULATOR receiver
KUC3_RS13860	COG0438	transferase activity, transferring glycosyl groups
KUC3_RS13905	COG0297	glycogen (starch) synthase activity
KUC3_RS13920	COG0367	asparagine synthase
KUC3_RS13950	COG0367	asparagine synthase
KUC3_RS13985	COG0489	protein tyrosine kinase activity
KUC3_RS13995	COG3267	Type II secretory pathway component ExeA
KUC3_RS13995	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_RS14000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC3_RS14000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_RS14025	COG1560	Kdo2-lipid A biosynthetic process
KUC3_RS14040	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS14055	COG1435	thymidine kinase activity
KUC3_RS14065	COG1609	Transcriptional regulator
KUC3_RS14070	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KUC3_RS14090	COG1082	Xylose isomerase domain protein TIM barrel
KUC3_RS14100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_RS14115	COG1982	Orn Lys Arg decarboxylase major
KUC3_RS14130	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS14155	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KUC3_RS14160	COG0789	Transcriptional regulator
KUC3_RS14195	COG1960	acyl-CoA dehydrogenase activity
KUC3_RS14260	COG4771	TonB-dependent receptor
KUC3_RS14275	COG1295	ribonuclease BN
KUC3_RS14295	COG3279	Response regulator of the LytR AlgR family
KUC3_RS14300	COG2819	hydrolase of the alpha beta superfamily
KUC3_RS14310	COG4977	sequence-specific DNA binding
KUC3_RS14310	COG1917	Cupin 2, conserved barrel domain protein
KUC3_RS14340	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_RS14440	COG4650	regulator
KUC3_RS14460	COG1690	Belongs to the RtcB family
KUC3_RS14465	COG0430	RNA-3'-phosphate cyclase activity
KUC3_RS14470	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KUC3_RS14475	COG1690	Belongs to the RtcB family
KUC3_RS14485	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KUC3_RS14485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KUC3_RS14500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KUC3_RS14530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC3_RS14530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC3_RS14550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC3_RS14560	COG0738	Major facilitator superfamily
KUC3_RS14565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_RS14570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC3_RS14575	COG2971	BadF BadG BcrA BcrD
KUC3_RS14590	COG1609	Transcriptional regulator
KUC3_RS14600	COG0583	DNA-binding transcription factor activity
KUC3_RS14625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_RS14630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_RS14635	COG0006	proline dipeptidase activity
KUC3_RS14650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_RS14660	COG0784	Response regulator, receiver
KUC3_RS14660	COG5002	protein histidine kinase activity
KUC3_RS14660	COG2198	Histidine kinase
KUC3_RS14665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KUC3_RS14675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KUC3_RS14680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC3_RS14700	COG3313	Fe-S protein
KUC3_RS14730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_RS14735	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_RS14740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KUC3_RS14760	COG3577	Aspartyl protease
KUC3_RS14765	COG0157	Belongs to the NadC ModD family
KUC3_RS14770	COG4969	Belongs to the N-Me-Phe pilin family
KUC3_RS14775	COG1459	type II secretion system
KUC3_RS14780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KUC3_RS14785	COG0237	dephospho-CoA kinase activity
KUC3_RS14790	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KUC3_RS14795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KUC3_RS14805	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_RS14805	COG1902	pentaerythritol trinitrate reductase activity
KUC3_RS14810	COG2988	succinylglutamate desuccinylase activity
KUC3_RS14815	COG0494	nUDIX hydrolase
KUC3_RS14825	COG0739	heme binding
KUC3_RS14830	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KUC3_RS14835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC3_RS14840	COG0849	cell division
KUC3_RS14845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KUC3_RS14850	COG1181	Belongs to the D-alanine--D-alanine ligase family
KUC3_RS14855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC3_RS14865	COG0772	Belongs to the SEDS family
KUC3_RS14870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KUC3_RS14880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KUC3_RS14885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KUC3_RS14890	COG0768	penicillin binding
KUC3_RS14895	COG3116	cell division
KUC3_RS14905	COG2001	Belongs to the MraZ family
KUC3_RS14925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_RS14950	COG0678	peroxiredoxin activity
KUC3_RS14950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC3_RS15005	COG0668	transmembrane transport
KUC3_RS15010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KUC3_RS15015	COG0189	ligase activity
KUC3_RS15020	COG1678	Uncharacterized ACR, COG1678
KUC3_RS15025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KUC3_RS15050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KUC3_RS15055	COG0762	integral membrane protein
KUC3_RS15085	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_RS15085	COG1902	pentaerythritol trinitrate reductase activity
KUC3_RS15105	COG0625	glutathione transferase activity
KUC3_RS15115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KUC3_RS15130	COG2378	regulation of single-species biofilm formation
KUC3_RS15155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KUC3_RS15165	COG0083	homoserine kinase activity
KUC3_RS15175	COG0583	DNA-binding transcription factor activity
KUC3_RS15185	COG2197	response regulator
KUC3_RS15190	COG4585	Histidine kinase
KUC3_RS15205	COG0840	transmembrane signaling receptor activity
KUC3_RS15210	COG0640	Transcriptional regulator
KUC3_RS15220	COG0431	NADPH-dependent FMN reductase
KUC3_RS15225	COG0798	PFAM Bile acid sodium symporter
KUC3_RS15230	COG2197	response regulator
KUC3_RS15235	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KUC3_RS15245	COG3850	Histidine kinase
KUC3_RS15245	COG5002	protein histidine kinase activity
KUC3_RS15270	COG1748	Saccharopine dehydrogenase
KUC3_RS15280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KUC3_RS15285	COG3107	peptidoglycan biosynthetic process
KUC3_RS15300	COG2823	Periplasmic or secreted lipoprotein
KUC3_RS15320	COG4585	Histidine kinase
KUC3_RS15325	COG2197	response regulator
KUC3_RS15345	COG1802	Transcriptional regulator
KUC3_RS15350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KUC3_RS15355	COG0372	Belongs to the citrate synthase family
KUC3_RS15360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KUC3_RS15365	COG2828	Protein conserved in bacteria
KUC3_RS15370	COG2203	Gaf domain
KUC3_RS15370	COG2199	diguanylate cyclase activity
KUC3_RS15385	COG2198	Histidine kinase
KUC3_RS15385	COG5002	protein histidine kinase activity
KUC3_RS15385	COG0784	Response regulator, receiver
KUC3_RS15390	COG3023	N-Acetylmuramoyl-L-alanine amidase
KUC3_RS15395	COG0067	glutamate synthase
KUC3_RS15395	COG0069	glutamate synthase activity
KUC3_RS15395	COG0070	glutamate synthase
KUC3_RS15400	COG0493	'glutamate synthase
KUC3_RS15405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC3_RS15425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC3_RS15430	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KUC3_RS15435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KUC3_RS15440	COG1054	Belongs to the UPF0176 family
KUC3_RS15455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC3_RS15460	COG5507	3-demethylubiquinone-9 3-methyltransferase
KUC3_RS15465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KUC3_RS15470	COG1196	nuclear chromosome segregation
KUC3_RS15470	COG0741	lytic transglycosylase activity
KUC3_RS15470	COG0739	heme binding
KUC3_RS15500	COG0625	glutathione transferase activity
KUC3_RS15520	COG2326	polyphosphate kinase activity
KUC3_RS15535	COG1215	transferase activity, transferring glycosyl groups
KUC3_RS15550	COG2204	response regulator
KUC3_RS15565	COG2894	cell division
KUC3_RS15570	COG0850	regulation of cytokinetic process
KUC3_RS15590	COG1981	membrane
KUC3_RS15605	COG1914	H( )-stimulated, divalent metal cation uptake system
KUC3_RS15620	COG1217	gtp-binding protein TYPA
KUC3_RS15625	COG0174	glutamine synthetase
KUC3_RS15635	COG3852	Histidine kinase
KUC3_RS15650	COG3437	response regulator, receiver
KUC3_RS15685	COG0525	valine-tRNA ligase activity
KUC3_RS15690	COG2927	DNA polymerase III (CHI subunit)
KUC3_RS15695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KUC3_RS15700	COG0795	lipopolysaccharide-transporting ATPase activity
KUC3_RS15705	COG0795	lipopolysaccharide-transporting ATPase activity
KUC3_RS15715	COG0673	inositol 2-dehydrogenase activity
KUC3_RS15805	COG0464	growth
KUC3_RS15850	COG3341	Caulimovirus viroplasmin
KUC3_RS15850	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_RS15865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC3_RS15890	COG0210	DNA helicase
KUC3_RS16005	COG0745	RESPONSE REGULATOR receiver
KUC3_RS16025	COG1024	Enoyl-CoA hydratase
KUC3_RS16050	COG1215	transferase activity, transferring glycosyl groups
KUC3_RS16055	COG0438	transferase activity, transferring glycosyl groups
KUC3_RS16125	COG0277	FAD linked oxidase domain protein
KUC3_RS16180	COG0513	Belongs to the DEAD box helicase family
KUC3_RS16205	COG2202	Pas domain
KUC3_RS16205	COG2199	diguanylate cyclase activity
KUC3_RS16205	COG2200	EAL domain
KUC3_RS16215	COG3568	Endonuclease Exonuclease Phosphatase
KUC3_RS16230	COG0730	response to heat
KUC3_RS16235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC3_RS16250	COG4191	Histidine kinase
KUC3_RS16250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS16260	COG0417	DNA replication proofreading
KUC3_RS16330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_RS16340	COG1573	uracil-dna glycosylase
KUC3_RS16345	COG3300	MHYT domain
KUC3_RS16345	COG5001	Diguanylate cyclase
KUC3_RS16365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC3_RS16385	COG1983	PspC domain protein
KUC3_RS16390	COG1842	Phage shock protein A
KUC3_RS16405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_RS16420	COG0542	response to heat
KUC3_RS16435	COG0204	Acyl-transferase
KUC3_RS16440	COG0204	Acyl-transferase
KUC3_RS16445	COG0668	transmembrane transport
KUC3_RS16460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KUC3_RS16465	COG0733	neurotransmitter:sodium symporter activity
KUC3_RS16480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KUC3_RS16505	COG0848	biopolymer transport protein
KUC3_RS16515	COG0457	Tetratricopeptide repeat
KUC3_RS16520	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KUC3_RS16545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KUC3_RS16550	COG0702	epimerase
KUC3_RS16570	COG5002	protein histidine kinase activity
KUC3_RS16570	COG5001	Diguanylate cyclase
KUC3_RS16580	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KUC3_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_RS16600	COG0583	DNA-binding transcription factor activity
KUC3_RS16605	COG0121	glutamine amidotransferase
KUC3_RS16635	COG4628	conserved protein (DUF2132)
KUC3_RS16640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_RS16650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KUC3_RS16660	COG1477	protein flavinylation
KUC3_RS16665	COG2871	sodium ion transport
KUC3_RS16670	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_RS16675	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_RS16680	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_RS16685	COG1805	sodium ion transport
KUC3_RS16690	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_RS16695	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KUC3_RS16700	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_RS16705	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KUC3_RS16720	COG0039	L-malate dehydrogenase activity
KUC3_RS16725	COG1438	arginine binding
KUC3_RS16750	COG0572	uridine kinase
KUC3_RS16755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KUC3_RS16780	COG0517	IMP dehydrogenase activity
KUC3_RS16780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KUC3_RS16785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS16795	COG0784	Response regulator, receiver
KUC3_RS16795	COG2205	protein histidine kinase activity
KUC3_RS16805	COG0189	ligase activity
KUC3_RS16815	COG0189	ligase activity
KUC3_RS16815	COG4067	protein conserved in archaea
KUC3_RS16830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUC3_RS16840	COG1283	sodium-dependent phosphate transmembrane transporter activity
KUC3_RS16845	COG0667	Aldo Keto reductase
KUC3_RS16865	COG5001	Diguanylate cyclase
KUC3_RS16865	COG3300	MHYT domain
KUC3_RS16895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KUC3_RS16905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KUC3_RS16910	COG0840	transmembrane signaling receptor activity
KUC3_RS16950	COG0583	DNA-binding transcription factor activity
KUC3_RS16965	COG1216	Glycosyl transferase, family 2
KUC3_RS16965	COG0438	transferase activity, transferring glycosyl groups
KUC3_RS17000	COG1442	glycosyl transferase family 8
KUC3_RS17000	COG1216	Glycosyl transferase, family 2
KUC3_RS17005	COG0463	Glycosyl transferase, family 2
KUC3_RS17055	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KUC3_RS17060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KUC3_RS17085	COG0202	RNA polymerase activity
KUC3_RS17110	COG0201	protein transport
KUC3_RS17130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KUC3_RS17165	COG2205	protein histidine kinase activity
KUC3_RS17165	COG0784	Response regulator, receiver
KUC3_RS17180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_RS17185	COG0557	exoribonuclease II activity
KUC3_RS17210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KUC3_RS17260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KUC3_RS17270	COG4251	negative regulation of phosphorylation
KUC3_RS17290	COG3706	GGDEF domain
KUC3_RS17305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KUC3_RS17305	COG0456	acetyltransferase
KUC3_RS17315	COG0583	DNA-binding transcription factor activity
KUC3_RS17335	COG1271	oxidase subunit
KUC3_RS17340	COG1294	oxidase, subunit
KUC3_RS17350	COG1522	sequence-specific DNA binding
KUC3_RS17360	COG1278	Cold shock
KUC3_RS17365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC3_RS17385	COG0339	signal peptide processing
KUC3_RS17390	COG2201	protein-glutamate methylesterase activity
KUC3_RS17400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_RS17400	COG4191	Histidine kinase
KUC3_RS17410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_RS17415	COG3437	response regulator, receiver
KUC3_RS17425	COG1506	peptidase
KUC3_RS17425	COG4946	Tricorn protease homolog
KUC3_RS17425	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_RS17460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KUC3_RS17465	COG1278	Cold shock
KUC3_RS17485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC3_RS17490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KUC3_RS17505	COG0281	malic enzyme
KUC3_RS17515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KUC3_RS17545	COG0456	acetyltransferase
KUC3_RS17555	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC3_RS17560	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC3_RS17565	COG2177	Part of the ABC transporter FtsEX involved in
KUC3_RS17570	COG2884	Cell division ATP-binding protein ftsE
KUC3_RS17575	COG0552	protein localization to endoplasmic reticulum
KUC3_RS17580	COG0742	ribosomal rna small subunit methyltransferase
KUC3_RS17590	COG2095	MarC family integral membrane protein
KUC3_RS17610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KUC3_RS17615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC3_RS17625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KUC3_RS17640	COG0076	glutamate decarboxylase activity
KUC3_RS17655	COG0842	Transport permease protein
KUC3_RS17660	COG1131	(ABC) transporter
KUC3_RS17665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KUC3_RS17675	COG0745	RESPONSE REGULATOR receiver
KUC3_RS17680	COG2205	protein histidine kinase activity
KUC3_RS17685	COG4774	siderophore transport
KUC3_RS17710	COG1253	flavin adenine dinucleotide binding
KUC3_RS17715	COG0701	Predicted permease
KUC3_RS17720	COG1966	Carbon starvation protein
KUC3_RS17760	COG0848	biopolymer transport protein
KUC3_RS17780	COG0657	acetylesterase activity
KUC3_RS17795	COG1733	regulation of RNA biosynthetic process
KUC3_RS17805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KUC3_RS17810	COG0049	tRNA binding
KUC3_RS17815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KUC3_RS17820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KUC3_RS17825	COG0085	RNA polymerase activity
KUC3_RS17830	COG0222	ribosome binding
KUC3_RS17835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KUC3_RS17840	COG0081	regulation of translation
KUC3_RS17845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KUC3_RS17860	COG0250	Participates in transcription elongation, termination and antitermination
KUC3_RS17865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC3_RS17875	COG1132	(ABC) transporter
KUC3_RS17885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KUC3_RS17890	COG3590	peptidase
KUC3_RS17905	COG0513	Belongs to the DEAD box helicase family
KUC3_RS17915	COG0418	dihydroorotase activity
KUC3_RS17920	COG3040	lipid binding
KUC3_RS17925	COG4989	oxidoreductase activity
KUC3_RS17930	COG0346	lactoylglutathione lyase activity
KUC3_RS17935	COG0668	transmembrane transport
KUC3_RS17955	COG0302	gtp cyclohydrolase
KUC3_RS17965	COG2957	Belongs to the agmatine deiminase family
KUC3_RS17970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_RS17980	COG1201	RNA secondary structure unwinding
KUC3_RS17990	COG1793	dna ligase
KUC3_RS17995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_RS18010	COG0583	DNA-binding transcription factor activity
KUC3_RS18020	COG0625	glutathione transferase activity
KUC3_RS18025	COG0625	glutathione transferase activity
KUC3_RS18035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KUC3_RS18040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_RS18050	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS18055	COG0028	Belongs to the TPP enzyme family
KUC3_RS18065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KUC3_RS18070	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KUC3_RS18075	COG0330	HflC and HflK could
KUC3_RS18080	COG0330	HflC and HflK could
KUC3_RS18085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KUC3_RS18090	COG1923	regulation of RNA biosynthetic process
KUC3_RS18095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KUC3_RS18100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KUC3_RS18105	COG0860	N-Acetylmuramoyl-L-alanine amidase
KUC3_RS18110	COG0802	atpase or kinase
KUC3_RS18115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KUC3_RS18115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KUC3_RS18120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KUC3_RS18135	COG2816	NAD+ diphosphatase activity
KUC3_RS18145	COG0735	belongs to the Fur family
KUC3_RS18165	COG0305	Participates in initiation and elongation during chromosome replication
KUC3_RS18190	COG2258	MOSC domain
KUC3_RS18235	COG0577	efflux transmembrane transporter activity
KUC3_RS18235	COG1136	(ABC) transporter
KUC3_RS18245	COG0840	transmembrane signaling receptor activity
KUC3_RS18250	COG5002	protein histidine kinase activity
KUC3_RS18255	COG0840	transmembrane signaling receptor activity
KUC3_RS18270	COG2855	membrane
KUC3_RS18280	COG0656	L-ascorbic acid biosynthetic process
KUC3_RS18300	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_RS18305	COG4771	TonB-dependent receptor
KUC3_RS18335	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC3_RS18350	COG1609	Transcriptional regulator
KUC3_RS18355	COG2814	Major facilitator Superfamily
KUC3_RS18355	COG0477	Major facilitator Superfamily
KUC3_RS18360	COG1618	nucleotide phosphatase activity, acting on free nucleotides
KUC3_RS18360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC3_RS18365	COG4988	ABC transporter
KUC3_RS18370	COG4890	Cyd operon protein YbgT
KUC3_RS18375	COG1294	oxidase, subunit
KUC3_RS18385	COG3829	transcription factor binding
KUC3_RS18415	COG4319	ketosteroid isomerase
KUC3_RS18420	COG1335	isochorismatase
KUC3_RS18430	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_RS18435	COG1741	Belongs to the pirin family
KUC3_RS18445	COG4771	TonB-dependent receptor
KUC3_RS18460	COG1469	GTP cyclohydrolase I activity
KUC3_RS18500	COG0811	peptide transport
KUC3_RS18540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC3_RS18575	COG2203	Gaf domain
KUC3_RS18575	COG5001	Diguanylate cyclase
KUC3_RS18575	COG4251	negative regulation of phosphorylation
KUC3_RS18575	COG3706	GGDEF domain
KUC3_RS18580	COG1477	protein flavinylation
KUC3_RS18610	COG3237	CsbD-like
KUC3_RS18625	COG0596	Alpha beta hydrolase
KUC3_RS18625	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_RS18650	COG3038	cytochrome b561
KUC3_RS18655	COG2353	YceI-like domain
KUC3_RS18660	COG1252	NADH dehydrogenase
KUC3_RS18685	COG2067	long-chain fatty acid transport protein
KUC3_RS18690	COG2203	Gaf domain
KUC3_RS18690	COG5001	Diguanylate cyclase
KUC3_RS18690	COG3706	GGDEF domain
KUC3_RS18690	COG4251	negative regulation of phosphorylation
KUC3_RS18695	COG4191	Histidine kinase
KUC3_RS18700	COG2204	response regulator
KUC3_RS18705	COG1136	(ABC) transporter
KUC3_RS18705	COG0577	efflux transmembrane transporter activity
KUC3_RS18710	COG0577	efflux transmembrane transporter activity
KUC3_RS18710	COG1136	(ABC) transporter
KUC3_RS18720	COG5001	Diguanylate cyclase
KUC3_RS18720	COG5002	protein histidine kinase activity
KUC3_RS18730	COG0010	Belongs to the arginase family
KUC3_RS18735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC3_RS18745	COG0673	inositol 2-dehydrogenase activity
KUC3_RS18780	COG1166	arginine decarboxylase activity
KUC3_RS18790	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KUC3_RS18870	COG5001	Diguanylate cyclase
KUC3_RS18875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_RS18880	COG1695	Transcriptional regulator
KUC3_RS18935	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_RS18960	COG3030	protein affecting phage T7 exclusion by the F plasmid
KUC3_RS18965	COG1324	tolerance protein
KUC3_RS18970	COG4232	protein-disulfide reductase activity
KUC3_RS18975	COG0739	heme binding
KUC3_RS18980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KUC3_RS18985	COG0511	ligase activity, forming carbon-carbon bonds
KUC3_RS18990	COG0439	Biotin carboxylase
KUC3_RS19035	COG0154	amidase activity
KUC3_RS19050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_RS19055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KUC3_RS19070	COG0151	Belongs to the GarS family
KUC3_RS19080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KUC3_RS19085	COG3954	Phosphoribulokinase
KUC3_RS19115	COG1501	Belongs to the glycosyl hydrolase 31 family
KUC3_RS19125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KUC3_RS19130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KUC3_RS19140	COG3031	protein transport across the cell outer membrane
KUC3_RS19150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC3_RS19155	COG1459	type II secretion system
KUC3_RS19160	COG2165	general secretion pathway protein
KUC3_RS19165	COG2165	general secretion pathway protein
KUC3_RS19170	COG2165	general secretion pathway protein
KUC3_RS19175	COG4795	General secretion pathway protein
KUC3_RS19190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KUC3_RS19210	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_RS19220	COG1011	Hydrolase
KUC3_RS19225	COG0494	nUDIX hydrolase
KUC3_RS19230	COG1218	3'(2'),5'-bisphosphate nucleotidase
KUC3_RS19240	COG2943	transferase activity, transferring hexosyl groups
KUC3_RS19245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KUC3_RS19255	COG3089	Belongs to the UPF0270 family
KUC3_RS19260	COG0429	hydrolase of the alpha beta-hydrolase fold
KUC3_RS19270	COG0488	(ABC) transporter
KUC3_RS19310	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_RS19315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC3_RS19320	COG2183	response to ionizing radiation
KUC3_RS19335	COG0596	Alpha beta hydrolase
KUC3_RS19340	COG1040	competence protein
KUC3_RS19360	COG1794	racemase activity, acting on amino acids and derivatives
KUC3_RS19375	COG0534	Mate efflux family protein
KUC3_RS19380	COG0726	polysaccharide deacetylase
KUC3_RS19380	COG1649	PFAM Uncharacterised BCR, COG1649
KUC3_RS19390	COG1999	signal sequence binding
KUC3_RS19395	COG0109	protoheme IX farnesyltransferase activity
KUC3_RS19400	COG1612	heme a metabolic process
KUC3_RS19425	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KUC3_RS19430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KUC3_RS19435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KUC3_RS19460	COG0129	dihydroxy-acid dehydratase activity
KUC3_RS19465	COG2860	membrane
KUC3_RS19470	COG0606	chelatase, subunit chli
KUC3_RS19475	COG0583	DNA-binding transcription factor activity
KUC3_RS19515	COG2814	Major facilitator Superfamily
KUC3_RS19520	COG1073	alpha beta
KUC3_RS19525	COG0729	surface antigen
KUC3_RS19530	COG2911	Protein conserved in bacteria
KUC3_RS19540	COG1595	DNA-templated transcription, initiation
KUC3_RS19555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC3_RS19565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC3_RS19585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC3_RS19610	COG1228	amidohydrolase
KUC3_RS19635	COG0425	Belongs to the sulfur carrier protein TusA family
KUC3_RS19650	COG1561	YicC-like family, N-terminal region
KUC3_RS19675	COG0270	DNA (cytosine-5-)-methyltransferase activity
KUC3_RS19725	COG2211	Major facilitator Superfamily
KUC3_RS19730	COG1609	Transcriptional regulator
KUC3_RS19745	COG2199	diguanylate cyclase activity
KUC3_RS19745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KUC3_RS19750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KUC3_RS19770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KUC3_RS19790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KUC3_RS19795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KUC3_RS19815	COG1475	DNA binding
KUC3_RS19820	COG1192	Involved in chromosome partitioning
KUC3_RS19835	COG0488	(ABC) transporter
KUC3_RS19850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC3_RS19855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KUC3_RS19890	COG0706	membrane insertase activity
KUC3_RS19895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KUC3_RS19900	COG0594	ribonuclease P activity
KUC3_RS19905	COG0230	Belongs to the bacterial ribosomal protein bL34 family