locus-tag	class	description
AMBT_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMBT_RS00020	COG0187	DNA topoisomerase II activity
AMBT_RS00040	COG2818	Glycosylase
AMBT_RS00050	COG3078	GTPase activator activity
AMBT_RS00065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMBT_RS00065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMBT_RS00070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AMBT_RS00075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMBT_RS00090	COG0569	domain protein
AMBT_RS00095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMBT_RS00095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMBT_RS00115	COG0758	DNA mediated transformation
AMBT_RS00130	COG0009	L-threonylcarbamoyladenylate synthase
AMBT_RS00135	COG0408	coproporphyrinogen oxidase activity
AMBT_RS00140	COG3047	cAMP biosynthetic process
AMBT_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMBT_RS00185	COG0583	DNA-binding transcription factor activity
AMBT_RS00220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMBT_RS00225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMBT_RS00225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMBT_RS00230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMBT_RS00265	COG0753	catalase activity
AMBT_RS00270	COG4584	PFAM Integrase catalytic
AMBT_RS00275	COG1484	DNA-dependent DNA replication
AMBT_RS00280	COG0753	catalase activity
AMBT_RS00295	COG0667	Aldo Keto reductase
AMBT_RS00300	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMBT_RS00310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMBT_RS00325	COG0189	ligase activity
AMBT_RS00325	COG4067	protein conserved in archaea
AMBT_RS00335	COG0189	ligase activity
AMBT_RS00345	COG2198	Histidine kinase
AMBT_RS00345	COG0784	Response regulator, receiver
AMBT_RS00345	COG2205	protein histidine kinase activity
AMBT_RS00355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMBT_RS00380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AMBT_RS00395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMBT_RS00400	COG0572	uridine kinase
AMBT_RS00430	COG1438	arginine binding
AMBT_RS00435	COG0039	L-malate dehydrogenase activity
AMBT_RS00450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMBT_RS00455	COG0545	Peptidyl-prolyl cis-trans isomerase
AMBT_RS00460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMBT_RS00465	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMBT_RS00470	COG1805	sodium ion transport
AMBT_RS00475	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMBT_RS00480	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMBT_RS00485	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMBT_RS00490	COG2871	sodium ion transport
AMBT_RS00495	COG1477	protein flavinylation
AMBT_RS00505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMBT_RS00515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMBT_RS00525	COG0121	glutamine amidotransferase
AMBT_RS00535	COG0583	DNA-binding transcription factor activity
AMBT_RS00545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMBT_RS00550	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AMBT_RS00560	COG5002	protein histidine kinase activity
AMBT_RS00560	COG5001	Diguanylate cyclase
AMBT_RS00575	COG0702	epimerase
AMBT_RS00580	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMBT_RS00605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AMBT_RS00610	COG0457	Tetratricopeptide repeat
AMBT_RS00620	COG0848	biopolymer transport protein
AMBT_RS00645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMBT_RS00660	COG0733	neurotransmitter:sodium symporter activity
AMBT_RS00665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMBT_RS00680	COG0668	transmembrane transport
AMBT_RS00685	COG0204	Acyl-transferase
AMBT_RS00690	COG0204	Acyl-transferase
AMBT_RS00695	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMBT_RS00720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMBT_RS00730	COG1842	Phage shock protein A
AMBT_RS00760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMBT_RS00780	COG3300	MHYT domain
AMBT_RS00780	COG5001	Diguanylate cyclase
AMBT_RS00785	COG1573	uracil-dna glycosylase
AMBT_RS00795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMBT_RS00815	COG1309	transcriptional regulator
AMBT_RS00865	COG0417	DNA replication proofreading
AMBT_RS00875	COG4191	Histidine kinase
AMBT_RS00890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMBT_RS00895	COG0730	response to heat
AMBT_RS00910	COG3568	Endonuclease Exonuclease Phosphatase
AMBT_RS00945	COG3264	Mechanosensitive ion channel
AMBT_RS00945	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMBT_RS00950	COG2186	Transcriptional regulator
AMBT_RS00955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMBT_RS00960	COG0800	Aldolase
AMBT_RS00990	COG0513	Belongs to the DEAD box helicase family
AMBT_RS00995	COG1716	ATPase activity
AMBT_RS00995	COG1131	(ABC) transporter
AMBT_RS00995	COG0842	Transport permease protein
AMBT_RS01075	COG0583	DNA-binding transcription factor activity
AMBT_RS01095	COG2963	transposase activity
AMBT_RS01100	COG2801	Transposase and inactivated derivatives
AMBT_RS01120	COG4585	Histidine kinase
AMBT_RS01125	COG2197	response regulator
AMBT_RS01135	COG3901	Regulator of nitric oxide reductase transcription
AMBT_RS01135	COG0348	domain, Protein
AMBT_RS01145	COG0784	Response regulator, receiver
AMBT_RS01145	COG2205	protein histidine kinase activity
AMBT_RS01175	COG0535	radical SAM domain protein
AMBT_RS01185	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AMBT_RS01190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMBT_RS01195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMBT_RS01205	COG1131	(ABC) transporter
AMBT_RS01245	COG3706	GGDEF domain
AMBT_RS01250	COG3706	GGDEF domain
AMBT_RS01270	COG0395	ABC-type sugar transport system, permease component
AMBT_RS01325	COG0251	oxidation-reduction process
AMBT_RS01340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMBT_RS01360	COG0673	inositol 2-dehydrogenase activity
AMBT_RS01420	COG0795	lipopolysaccharide-transporting ATPase activity
AMBT_RS01425	COG0795	lipopolysaccharide-transporting ATPase activity
AMBT_RS01430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMBT_RS01435	COG2927	DNA polymerase III (CHI subunit)
AMBT_RS01440	COG0525	valine-tRNA ligase activity
AMBT_RS01475	COG3437	response regulator, receiver
AMBT_RS01485	COG3852	Histidine kinase
AMBT_RS01495	COG0174	glutamine synthetase
AMBT_RS01500	COG1217	gtp-binding protein TYPA
AMBT_RS01515	COG1914	H( )-stimulated, divalent metal cation uptake system
AMBT_RS01530	COG1981	membrane
AMBT_RS01555	COG0850	regulation of cytokinetic process
AMBT_RS01560	COG2894	cell division
AMBT_RS01580	COG0625	glutathione transferase activity
AMBT_RS01585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMBT_RS01595	COG1902	pentaerythritol trinitrate reductase activity
AMBT_RS01605	COG0738	Major facilitator superfamily
AMBT_RS01620	COG0739	heme binding
AMBT_RS01625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMBT_RS01640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMBT_RS01655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMBT_RS01670	COG1476	TRANSCRIPTIONal
AMBT_RS01680	COG0493	'glutamate synthase
AMBT_RS01685	COG0070	glutamate synthase
AMBT_RS01685	COG0069	glutamate synthase activity
AMBT_RS01685	COG0067	glutamate synthase
AMBT_RS01690	COG5002	protein histidine kinase activity
AMBT_RS01690	COG0784	Response regulator, receiver
AMBT_RS01690	COG2198	Histidine kinase
AMBT_RS01705	COG2199	diguanylate cyclase activity
AMBT_RS01705	COG2203	Gaf domain
AMBT_RS01710	COG2828	Protein conserved in bacteria
AMBT_RS01720	COG0372	Belongs to the citrate synthase family
AMBT_RS01725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMBT_RS01735	COG4771	TonB-dependent receptor
AMBT_RS01740	COG2197	response regulator
AMBT_RS01745	COG4585	Histidine kinase
AMBT_RS01810	COG2823	Periplasmic or secreted lipoprotein
AMBT_RS01820	COG0792	nuclease activity
AMBT_RS01825	COG3107	peptidoglycan biosynthetic process
AMBT_RS01830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMBT_RS01845	COG1748	Saccharopine dehydrogenase
AMBT_RS01870	COG5002	protein histidine kinase activity
AMBT_RS01875	COG0745	RESPONSE REGULATOR receiver
AMBT_RS01880	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMBT_RS01885	COG2201	protein-glutamate methylesterase activity
AMBT_RS01890	COG0798	PFAM Bile acid sodium symporter
AMBT_RS01895	COG0431	NADPH-dependent FMN reductase
AMBT_RS01905	COG0640	Transcriptional regulator
AMBT_RS01920	COG4585	Histidine kinase
AMBT_RS01925	COG2197	response regulator
AMBT_RS01935	COG0583	DNA-binding transcription factor activity
AMBT_RS01945	COG0083	homoserine kinase activity
AMBT_RS01955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMBT_RS01975	COG0625	glutathione transferase activity
AMBT_RS01980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMBT_RS01995	COG1902	pentaerythritol trinitrate reductase activity
AMBT_RS01995	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMBT_RS02010	COG0762	integral membrane protein
AMBT_RS02015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMBT_RS02020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMBT_RS02040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMBT_RS02045	COG1678	Uncharacterized ACR, COG1678
AMBT_RS02050	COG0189	ligase activity
AMBT_RS02055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMBT_RS02060	COG0668	transmembrane transport
AMBT_RS02080	COG2198	Histidine kinase
AMBT_RS02080	COG5002	protein histidine kinase activity
AMBT_RS02080	COG0784	Response regulator, receiver
AMBT_RS02085	COG2204	response regulator
AMBT_RS02100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMBT_RS02100	COG0678	peroxiredoxin activity
AMBT_RS02125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS02140	COG2001	Belongs to the MraZ family
AMBT_RS02150	COG3116	cell division
AMBT_RS02155	COG0768	penicillin binding
AMBT_RS02160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMBT_RS02165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMBT_RS02175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMBT_RS02180	COG0772	Belongs to the SEDS family
AMBT_RS02190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMBT_RS02195	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMBT_RS02200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMBT_RS02205	COG0849	cell division
AMBT_RS02215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMBT_RS02220	COG0739	heme binding
AMBT_RS02230	COG0494	nUDIX hydrolase
AMBT_RS02235	COG2988	succinylglutamate desuccinylase activity
AMBT_RS02240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMBT_RS02245	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AMBT_RS02250	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMBT_RS02250	COG0237	dephospho-CoA kinase activity
AMBT_RS02255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMBT_RS02260	COG1459	type II secretion system
AMBT_RS02265	COG4969	Belongs to the N-Me-Phe pilin family
AMBT_RS02295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMBT_RS02300	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMBT_RS02305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMBT_RS02345	COG3313	Fe-S protein
AMBT_RS02365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMBT_RS02370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMBT_RS02375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMBT_RS02390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMBT_RS02400	COG0006	proline dipeptidase activity
AMBT_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMBT_RS02410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMBT_RS02435	COG0583	DNA-binding transcription factor activity
AMBT_RS02450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMBT_RS02450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMBT_RS02495	COG5433	transposase activity
AMBT_RS02525	COG0656	L-ascorbic acid biosynthetic process
AMBT_RS02535	COG2814	Major facilitator Superfamily
AMBT_RS02580	COG0513	Belongs to the DEAD box helicase family
AMBT_RS02595	COG2133	pyrroloquinoline quinone binding
AMBT_RS02620	COG1136	(ABC) transporter
AMBT_RS02620	COG0577	efflux transmembrane transporter activity
AMBT_RS02625	COG1136	(ABC) transporter
AMBT_RS02625	COG0577	efflux transmembrane transporter activity
AMBT_RS02630	COG2204	response regulator
AMBT_RS02635	COG3852	Histidine kinase
AMBT_RS02650	COG0653	protein targeting
AMBT_RS02675	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AMBT_RS02690	COG1451	nucleotide metabolic process
AMBT_RS02705	COG1280	lysine exporter protein (LysE YggA)
AMBT_RS02710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMBT_RS02725	COG2319	Wd-40 repeat
AMBT_RS02725	COG4249	Peptidase C14 caspase catalytic subunit p20
AMBT_RS02745	COG0484	heat shock protein binding
AMBT_RS02755	COG0583	DNA-binding transcription factor activity
AMBT_RS02775	COG0514	ATP-dependent DNA helicase (RecQ)
AMBT_RS02780	COG1295	ribonuclease BN
AMBT_RS02790	COG1846	Transcriptional regulator
AMBT_RS02795	COG1566	PFAM secretion protein HlyD family protein
AMBT_RS02830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMBT_RS02835	COG0693	protein deglycase activity
AMBT_RS02840	COG4221	oxidoreductase activity
AMBT_RS02850	COG1971	Probably functions as a manganese efflux pump
AMBT_RS02855	COG0109	protoheme IX farnesyltransferase activity
AMBT_RS02875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMBT_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS02940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMBT_RS02955	COG1733	regulation of RNA biosynthetic process
AMBT_RS02960	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS02970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMBT_RS03035	COG0826	peptidase U32
AMBT_RS03040	COG1607	acyl-coa hydrolase
AMBT_RS03095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMBT_RS03105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMBT_RS03145	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS03185	COG3279	Response regulator of the LytR AlgR family
AMBT_RS03220	COG0189	ligase activity
AMBT_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS03235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS03250	COG0789	Transcriptional regulator
AMBT_RS03255	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AMBT_RS03265	COG4682	membrane
AMBT_RS03275	COG4774	siderophore transport
AMBT_RS03275	COG1629	transport
AMBT_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS03295	COG4773	Receptor
AMBT_RS03300	COG4774	siderophore transport
AMBT_RS03325	COG2815	serine threonine protein kinase
AMBT_RS03325	COG0515	serine threonine protein kinase
AMBT_RS03350	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AMBT_RS03355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMBT_RS03360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMBT_RS03365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMBT_RS03400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMBT_RS03405	COG1609	Transcriptional regulator
AMBT_RS03415	COG1435	thymidine kinase activity
AMBT_RS03425	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS03455	COG1560	Kdo2-lipid A biosynthetic process
AMBT_RS03475	COG2827	Endonuclease containing a URI domain
AMBT_RS03480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMBT_RS03480	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMBT_RS03485	COG3409	Peptidoglycan-binding domain 1 protein
AMBT_RS03485	COG3267	Type II secretory pathway component ExeA
AMBT_RS03540	COG1216	Glycosyl transferase, family 2
AMBT_RS03555	COG2755	lipolytic protein G-D-S-L family
AMBT_RS03555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMBT_RS03580	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS03605	COG1045	serine acetyltransferase
AMBT_RS03655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMBT_RS03670	COG0745	RESPONSE REGULATOR receiver
AMBT_RS03680	COG1785	Belongs to the alkaline phosphatase family
AMBT_RS03685	COG2066	Belongs to the glutaminase family
AMBT_RS03700	COG0754	glutathionylspermidine amidase activity
AMBT_RS03725	COG1842	Phage shock protein A
AMBT_RS03730	COG3789	protein conserved in bacteria
AMBT_RS03745	COG0343	queuine tRNA-ribosyltransferase activity
AMBT_RS03750	COG1862	Preprotein translocase
AMBT_RS03755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMBT_RS03760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMBT_RS03790	COG0483	inositol monophosphate 1-phosphatase activity
AMBT_RS03795	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMBT_RS03855	COG1104	cysteine desulfurase activity
AMBT_RS03860	COG0719	Fe-S assembly protein
AMBT_RS03865	COG0396	ATPase activity
AMBT_RS03870	COG0719	Fe-S assembly protein
AMBT_RS03875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMBT_RS03890	COG2166	iron-sulfur cluster assembly
AMBT_RS03900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMBT_RS03925	COG2976	Protein conserved in bacteria
AMBT_RS03930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMBT_RS03945	COG1570	exodeoxyribonuclease VII activity
AMBT_RS03950	COG0516	GMP reductase activity
AMBT_RS03950	COG0517	IMP dehydrogenase activity
AMBT_RS03965	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMBT_RS03975	COG1234	tRNA 3'-trailer cleavage
AMBT_RS03985	COG1720	tRNA m6t6A37 methyltransferase activity
AMBT_RS04025	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMBT_RS04030	COG0740	serine-type endopeptidase activity
AMBT_RS04035	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMBT_RS04040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMBT_RS04045	COG0776	regulation of translation
AMBT_RS04050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMBT_RS04075	COG0385	Bile acid
AMBT_RS04095	COG0268	Binds directly to 16S ribosomal RNA
AMBT_RS04100	COG0728	peptidoglycan biosynthetic process
AMBT_RS04105	COG0196	riboflavin kinase activity
AMBT_RS04110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMBT_RS04120	COG1047	Peptidyl-prolyl cis-trans
AMBT_RS04125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMBT_RS04185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMBT_RS04200	COG0354	folic acid binding
AMBT_RS04205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AMBT_RS04220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMBT_RS04225	COG1595	DNA-templated transcription, initiation
AMBT_RS04270	COG0084	hydrolase, TatD family'
AMBT_RS04280	COG0560	Phosphoserine phosphatase
AMBT_RS04290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMBT_RS04300	COG0488	(ABC) transporter
AMBT_RS04305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMBT_RS04320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMBT_RS04320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMBT_RS04335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMBT_RS04345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMBT_RS04350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AMBT_RS04360	COG0142	geranyltranstransferase activity
AMBT_RS04370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMBT_RS04380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMBT_RS04390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AMBT_RS04395	COG4221	oxidoreductase activity
AMBT_RS04410	COG1595	DNA-templated transcription, initiation
AMBT_RS04430	COG1496	oxidoreductase activity
AMBT_RS04435	COG0542	response to heat
AMBT_RS04455	COG1183	phosphatidylcholine synthase activity
AMBT_RS04490	COG4251	negative regulation of phosphorylation
AMBT_RS04490	COG3706	GGDEF domain
AMBT_RS04490	COG5001	Diguanylate cyclase
AMBT_RS04490	COG2203	Gaf domain
AMBT_RS04510	COG2319	Wd-40 repeat
AMBT_RS04510	COG4249	Peptidase C14 caspase catalytic subunit p20
AMBT_RS04520	COG3220	belongs to the UPF0276 family
AMBT_RS04530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMBT_RS04535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMBT_RS04565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMBT_RS04570	COG0326	Molecular chaperone. Has ATPase activity
AMBT_RS04590	COG3293	Transposase
AMBT_RS04600	COG0681	Belongs to the peptidase S26 family
AMBT_RS04610	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AMBT_RS04620	COG0140	phosphoribosyl-ATP diphosphatase activity
AMBT_RS04620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMBT_RS04635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMBT_RS04640	COG0131	Imidazoleglycerol-phosphate dehydratase
AMBT_RS04640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMBT_RS04645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMBT_RS04650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMBT_RS04655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMBT_RS04710	COG1199	ATP-dependent helicase activity
AMBT_RS04715	COG1214	PFAM Peptidase M22, glycoprotease
AMBT_RS04730	COG2267	carboxylic ester hydrolase activity
AMBT_RS04735	COG0318	PFAM AMP-dependent synthetase and ligase
AMBT_RS04740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMBT_RS04755	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMBT_RS04760	COG2983	Belongs to the UPF0260 family
AMBT_RS04765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMBT_RS04770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMBT_RS04780	COG2186	Transcriptional regulator
AMBT_RS04815	COG4399	Belongs to the UPF0754 family
AMBT_RS04820	COG1309	transcriptional regulator
AMBT_RS04850	COG1902	pentaerythritol trinitrate reductase activity
AMBT_RS04850	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMBT_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS04895	COG0463	Glycosyl transferase, family 2
AMBT_RS04915	COG0642	Histidine kinase
AMBT_RS04955	COG3101	peptidyl-lysine hydroxylation
AMBT_RS04985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMBT_RS04985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMBT_RS05010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMBT_RS05025	COG0101	tRNA pseudouridine synthase activity
AMBT_RS05035	COG0285	dihydrofolate synthase activity
AMBT_RS05040	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AMBT_RS05045	COG1286	toxin biosynthetic process
AMBT_RS05050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMBT_RS05075	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AMBT_RS05085	COG0604	alcohol dehydrogenase
AMBT_RS05095	COG2080	2 iron, 2 sulfur cluster binding
AMBT_RS05100	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMBT_RS05105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMBT_RS05140	COG1785	Belongs to the alkaline phosphatase family
AMBT_RS05145	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMBT_RS05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMBT_RS05170	COG0741	lytic transglycosylase activity
AMBT_RS05170	COG1388	LysM domain
AMBT_RS05175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMBT_RS05180	COG2226	methyltransferase
AMBT_RS05185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMBT_RS05185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMBT_RS05190	COG0489	protein tyrosine kinase activity
AMBT_RS05200	COG0471	metal ion transport
AMBT_RS05285	COG0582	viral genome integration into host DNA
AMBT_RS05310	COG3177	Filamentation induced by cAMP protein fic
AMBT_RS05335	COG1484	DNA-dependent DNA replication
AMBT_RS05365	COG1484	DNA-dependent DNA replication
AMBT_RS05400	COG0753	catalase activity
AMBT_RS05415	COG0840	transmembrane signaling receptor activity
AMBT_RS05425	COG2755	lipolytic protein G-D-S-L family
AMBT_RS05425	COG0657	acetylesterase activity
AMBT_RS05440	COG0738	Major facilitator superfamily
AMBT_RS05480	COG3850	Histidine kinase
AMBT_RS05480	COG5002	protein histidine kinase activity
AMBT_RS05485	COG0745	RESPONSE REGULATOR receiver
AMBT_RS05510	COG1764	response to oxidative stress
AMBT_RS05515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMBT_RS05540	COG5001	Diguanylate cyclase
AMBT_RS05540	COG3300	MHYT domain
AMBT_RS05555	COG0673	inositol 2-dehydrogenase activity
AMBT_RS05560	COG4948	Mandelate Racemase Muconate Lactonizing
AMBT_RS05565	COG1609	Transcriptional regulator
AMBT_RS05605	COG1024	Enoyl-CoA hydratase
AMBT_RS05615	COG2356	endonuclease I
AMBT_RS05635	COG3665	Urea carboxylase-associated protein
AMBT_RS05660	COG0745	RESPONSE REGULATOR receiver
AMBT_RS05665	COG2205	protein histidine kinase activity
AMBT_RS05705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMBT_RS05710	COG0469	pyruvate kinase activity
AMBT_RS05715	COG1737	Transcriptional regulator
AMBT_RS05720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMBT_RS05730	COG0129	dihydroxy-acid dehydratase activity
AMBT_RS05740	COG0800	Aldolase
AMBT_RS05745	COG0676	glucose-6-phosphate 1-epimerase activity
AMBT_RS05755	COG1640	4-alpha-glucanotransferase
AMBT_RS05760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMBT_RS05770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMBT_RS05790	COG2866	Carboxypeptidase
AMBT_RS05795	COG1115	amino acid carrier protein
AMBT_RS05805	COG3139	Protein of unknown function (DUF1315)
AMBT_RS05830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMBT_RS05855	COG2205	protein histidine kinase activity
AMBT_RS05855	COG0784	Response regulator, receiver
AMBT_RS05860	COG0784	Response regulator, receiver
AMBT_RS05865	COG4251	negative regulation of phosphorylation
AMBT_RS05875	COG2204	response regulator
AMBT_RS05885	COG0583	DNA-binding transcription factor activity
AMBT_RS05895	COG0640	Transcriptional regulator
AMBT_RS05910	COG0583	DNA-binding transcription factor activity
AMBT_RS05925	COG3132	Protein of unknown function, DUF480
AMBT_RS05935	COG5001	Diguanylate cyclase
AMBT_RS05935	COG3300	MHYT domain
AMBT_RS05940	COG1022	Amp-dependent synthetase and ligase
AMBT_RS05950	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AMBT_RS05955	COG1074	ATP-dependent DNA helicase activity
AMBT_RS05960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMBT_RS05975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMBT_RS05990	COG3268	Saccharopine dehydrogenase
AMBT_RS05995	COG0436	Aminotransferase
AMBT_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS06045	COG5433	transposase activity
AMBT_RS06120	COG3547	Transposase (IS116 IS110 IS902 family)
AMBT_RS06235	COG2801	Transposase and inactivated derivatives
AMBT_RS06285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMBT_RS06290	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMBT_RS06295	COG0315	cyclic pyranopterin monophosphate synthase activity
AMBT_RS06300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMBT_RS06305	COG0314	molybdopterin synthase activity
AMBT_RS06320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMBT_RS06345	COG4771	TonB-dependent receptor
AMBT_RS06385	COG0596	Alpha beta hydrolase
AMBT_RS06390	COG1024	Enoyl-CoA hydratase
AMBT_RS06390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMBT_RS06395	COG0183	Belongs to the thiolase family
AMBT_RS06400	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS06405	COG0596	Alpha beta hydrolase
AMBT_RS06415	COG2390	Transcriptional regulator
AMBT_RS06420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMBT_RS06430	COG0246	Mannitol dehydrogenase
AMBT_RS06450	COG0668	transmembrane transport
AMBT_RS06475	COG4771	TonB-dependent receptor
AMBT_RS06495	COG2198	Histidine kinase
AMBT_RS06495	COG2205	protein histidine kinase activity
AMBT_RS06495	COG0784	Response regulator, receiver
AMBT_RS06500	COG3437	response regulator, receiver
AMBT_RS06510	COG0195	Participates in both transcription termination and antitermination
AMBT_RS06525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMBT_RS06535	COG4269	membrane
AMBT_RS06540	COG0501	Belongs to the peptidase M48B family
AMBT_RS06545	COG3706	GGDEF domain
AMBT_RS06550	COG0596	Alpha beta hydrolase
AMBT_RS06560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMBT_RS06560	COG3153	acetyltransferase
AMBT_RS06620	COG1032	radical SAM domain protein
AMBT_RS06635	COG4771	TonB-dependent receptor
AMBT_RS06650	COG4134	Bacterial extracellular solute-binding protein
AMBT_RS06655	COG4135	transport system, permease component
AMBT_RS06660	COG4136	ATPase activity
AMBT_RS06665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMBT_RS06680	COG3706	GGDEF domain
AMBT_RS06680	COG2203	Gaf domain
AMBT_RS06680	COG4251	negative regulation of phosphorylation
AMBT_RS06680	COG5001	Diguanylate cyclase
AMBT_RS06710	COG0583	DNA-binding transcription factor activity
AMBT_RS06740	COG1595	DNA-templated transcription, initiation
AMBT_RS06750	COG1012	belongs to the aldehyde dehydrogenase family
AMBT_RS06775	COG3668	Plasmid stabilization system
AMBT_RS06785	COG2814	Major facilitator Superfamily
AMBT_RS06790	COG3293	Transposase
AMBT_RS06795	COG4771	TonB-dependent receptor
AMBT_RS06810	COG0582	viral genome integration into host DNA
AMBT_RS06845	COG2867	negative regulation of translational initiation
AMBT_RS06850	COG2914	Belongs to the UPF0125 (RnfH) family
AMBT_RS06860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMBT_RS06865	COG4771	TonB-dependent receptor
AMBT_RS06870	COG0457	Tetratricopeptide repeat
AMBT_RS06875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMBT_RS06880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMBT_RS06885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMBT_RS06895	COG0356	it plays a direct role in the translocation of protons across the membrane
AMBT_RS06915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMBT_RS06940	COG2814	Major facilitator Superfamily
AMBT_RS06985	COG1196	nuclear chromosome segregation
AMBT_RS06995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMBT_RS07000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMBT_RS07005	COG5002	protein histidine kinase activity
AMBT_RS07010	COG0745	RESPONSE REGULATOR receiver
AMBT_RS07035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS07080	COG2217	Heavy metal translocating P-type atpase
AMBT_RS07135	COG2132	Multicopper oxidase
AMBT_RS07270	COG1132	(ABC) transporter
AMBT_RS07275	COG1663	tetraacyldisaccharide 4'-kinase activity
AMBT_RS07315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMBT_RS07320	COG0435	Glutathione S-transferase
AMBT_RS07335	COG0372	Belongs to the citrate synthase family
AMBT_RS07345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMBT_RS07350	COG1053	succinate dehydrogenase
AMBT_RS07360	COG0567	Dehydrogenase, E1 component
AMBT_RS07365	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMBT_RS07390	COG2801	Transposase and inactivated derivatives
AMBT_RS07415	COG4667	esterase of the alpha-beta hydrolase superfamily
AMBT_RS07435	COG0366	Alpha amylase catalytic
AMBT_RS07445	COG0366	Alpha amylase catalytic
AMBT_RS07445	COG1874	Beta-galactosidase
AMBT_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS07465	COG2267	carboxylic ester hydrolase activity
AMBT_RS07475	COG0616	signal peptide processing
AMBT_RS07495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMBT_RS07500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMBT_RS07505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMBT_RS07510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMBT_RS07515	COG0386	Belongs to the glutathione peroxidase family
AMBT_RS07520	COG2084	Dehydrogenase
AMBT_RS07530	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS07535	COG1024	Enoyl-CoA hydratase
AMBT_RS07540	COG2226	methyltransferase
AMBT_RS07550	COG3083	sulfuric ester hydrolase activity
AMBT_RS07555	COG3082	Protein of unknown function (DUF1414)
AMBT_RS07560	COG3081	Nucleoid-associated protein
AMBT_RS07590	COG3275	phosphorelay sensor kinase activity
AMBT_RS07595	COG3279	Response regulator of the LytR AlgR family
AMBT_RS07600	COG0205	6-phosphofructokinase activity
AMBT_RS07610	COG2205	protein histidine kinase activity
AMBT_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMBT_RS07675	COG0513	Belongs to the DEAD box helicase family
AMBT_RS07680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMBT_RS07685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMBT_RS07690	COG0583	DNA-binding transcription factor activity
AMBT_RS07710	COG1760	l-serine dehydratase
AMBT_RS07715	COG0494	nUDIX hydrolase
AMBT_RS07735	COG1404	Belongs to the peptidase S8 family
AMBT_RS07740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMBT_RS07745	COG0022	dehydrogenase e1 component
AMBT_RS07755	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMBT_RS07760	COG0515	serine threonine protein kinase
AMBT_RS07765	COG1946	Acyl-CoA thioesterase
AMBT_RS07780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMBT_RS07790	COG1956	GAF domain-containing protein
AMBT_RS07805	COG0793	Belongs to the peptidase S41A family
AMBT_RS07810	COG0733	neurotransmitter:sodium symporter activity
AMBT_RS07815	COG1757	Na H antiporter
AMBT_RS07820	COG0308	aminopeptidase N
AMBT_RS07850	COG2902	Dehydrogenase
AMBT_RS07855	COG0167	dihydroorotate dehydrogenase activity
AMBT_RS07870	COG0488	(ABC) transporter
AMBT_RS07880	COG3130	regulation of translation
AMBT_RS07885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMBT_RS07895	COG0415	Belongs to the DNA photolyase family
AMBT_RS07900	COG0415	Belongs to the DNA photolyase family
AMBT_RS07905	COG3046	protein related to deoxyribodipyrimidine photolyase
AMBT_RS07955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMBT_RS07960	COG0589	response to stress
AMBT_RS07970	COG0069	glutamate synthase activity
AMBT_RS07985	COG2193	ferroxidase activity
AMBT_RS07995	COG3278	Belongs to the heme-copper respiratory oxidase family
AMBT_RS08010	COG2010	Cytochrome c
AMBT_RS08035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMBT_RS08040	COG0589	response to stress
AMBT_RS08045	COG0037	tRNA processing
AMBT_RS08050	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMBT_RS08070	COG1280	lysine exporter protein (LysE YggA)
AMBT_RS08080	COG2897	thiosulfate sulfurtransferase activity
AMBT_RS08085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AMBT_RS08090	COG3148	PFAM DTW domain containing protein
AMBT_RS08115	COG0322	excinuclease ABC activity
AMBT_RS08120	COG2197	response regulator
AMBT_RS08125	COG1741	Belongs to the pirin family
AMBT_RS08175	COG0745	RESPONSE REGULATOR receiver
AMBT_RS08210	COG0670	Belongs to the BI1 family
AMBT_RS08220	COG2923	Belongs to the DsrF TusC family
AMBT_RS08230	COG2920	part of a sulfur-relay system
AMBT_RS08235	COG0561	phosphatase activity
AMBT_RS08250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMBT_RS08255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMBT_RS08260	COG0531	amino acid
AMBT_RS08260	COG1674	ftsk spoiiie
AMBT_RS08270	COG0686	Belongs to the AlaDH PNT family
AMBT_RS08275	COG0284	orotidine-5'-phosphate decarboxylase activity
AMBT_RS08280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AMBT_RS08285	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AMBT_RS08295	COG0776	regulation of translation
AMBT_RS08300	COG0539	negative regulation of cytoplasmic translation
AMBT_RS08305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMBT_RS08310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMBT_RS08315	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMBT_RS08330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMBT_RS08335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMBT_RS08340	COG0633	Ferredoxin
AMBT_RS08345	COG5002	protein histidine kinase activity
AMBT_RS08350	COG0745	RESPONSE REGULATOR receiver
AMBT_RS08410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMBT_RS08420	COG3547	Transposase (IS116 IS110 IS902 family)
AMBT_RS08515	COG4584	PFAM Integrase catalytic
AMBT_RS08590	COG1131	(ABC) transporter
AMBT_RS08625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AMBT_RS08630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMBT_RS08640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMBT_RS08650	COG4783	chaperone-mediated protein folding
AMBT_RS08665	COG1393	Belongs to the ArsC family
AMBT_RS08700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMBT_RS08735	COG0572	uridine kinase
AMBT_RS08740	COG3769	mannosylglycerate metabolic process
AMBT_RS08745	COG1215	transferase activity, transferring glycosyl groups
AMBT_RS08755	COG0303	'Molybdopterin
AMBT_RS08760	COG0534	Mate efflux family protein
AMBT_RS08780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMBT_RS08805	COG3293	Transposase
AMBT_RS08820	COG0405	Gamma-glutamyltransferase
AMBT_RS08825	COG1024	Enoyl-CoA hydratase
AMBT_RS08860	COG1448	Aminotransferase
AMBT_RS08865	COG1671	Belongs to the UPF0178 family
AMBT_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS08880	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS08885	COG1917	Cupin 2, conserved barrel domain protein
AMBT_RS08885	COG2207	Transcriptional regulator
AMBT_RS08935	COG0596	Alpha beta hydrolase
AMBT_RS08945	COG0716	FMN binding
AMBT_RS08970	COG2610	gluconate transmembrane transporter activity
AMBT_RS08975	COG3265	gluconokinase activity
AMBT_RS08980	COG1609	Transcriptional regulator
AMBT_RS08990	COG1984	allophanate hydrolase subunit 2
AMBT_RS09005	COG2996	Protein conserved in bacteria
AMBT_RS09010	COG1765	OsmC-like protein
AMBT_RS09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS09025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS09040	COG0436	Aminotransferase
AMBT_RS09060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMBT_RS09065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMBT_RS09095	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMBT_RS09105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMBT_RS09115	COG1238	metal cluster binding
AMBT_RS09125	COG3012	SEC-C Motif Domain Protein
AMBT_RS09160	COG4628	conserved protein (DUF2132)
AMBT_RS09170	COG0454	-acetyltransferase
AMBT_RS09175	COG1119	ATPase activity
AMBT_RS09185	COG1185	polyribonucleotide nucleotidyltransferase activity
AMBT_RS09200	COG3293	Transposase
AMBT_RS09205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMBT_RS09210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMBT_RS09215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMBT_RS09250	COG5001	Diguanylate cyclase
AMBT_RS09250	COG3300	MHYT domain
AMBT_RS09260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMBT_RS09265	COG0149	triose-phosphate isomerase activity
AMBT_RS09270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMBT_RS09275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMBT_RS09285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMBT_RS09290	COG1534	Rna-binding protein
AMBT_RS09300	COG1067	ATP-dependent peptidase activity
AMBT_RS09305	COG0495	leucyl-tRNA aminoacylation
AMBT_RS09315	COG1466	dna polymerase III delta subunit
AMBT_RS09320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMBT_RS09325	COG0799	negative regulation of ribosome biogenesis
AMBT_RS09330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMBT_RS09335	COG0768	penicillin binding
AMBT_RS09340	COG0772	Belongs to the SEDS family
AMBT_RS09345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMBT_RS09350	COG1686	Belongs to the peptidase S11 family
AMBT_RS09355	COG2921	Belongs to the UPF0250 family
AMBT_RS09360	COG0321	lipoyl(octanoyl) transferase activity
AMBT_RS09365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMBT_RS09375	COG0252	asparaginase activity
AMBT_RS09385	COG0778	Nitroreductase
AMBT_RS09400	COG0616	signal peptide processing
AMBT_RS09420	COG0492	ferredoxin-NADP+ reductase activity
AMBT_RS09425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMBT_RS09430	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMBT_RS09435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMBT_RS09440	COG0542	response to heat
AMBT_RS09445	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMBT_RS09450	COG1278	Cold shock
AMBT_RS09460	COG1187	pseudouridine synthase activity
AMBT_RS09465	COG0482	sulfurtransferase activity
AMBT_RS09470	COG2915	High frequency lysogenization protein hflD homolog
AMBT_RS09475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMBT_RS09485	COG2850	peptidyl-arginine hydroxylation
AMBT_RS09500	COG0277	FAD linked oxidase domain protein
AMBT_RS09500	COG0247	lactate metabolic process
AMBT_RS09505	COG3123	guanosine phosphorylase activity
AMBT_RS09545	COG1695	Transcriptional regulator
AMBT_RS09590	COG3265	gluconokinase activity
AMBT_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS09615	COG1609	Transcriptional regulator
AMBT_RS09620	COG0679	Auxin Efflux Carrier
AMBT_RS09640	COG0574	Belongs to the PEP-utilizing enzyme family
AMBT_RS09640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMBT_RS09660	COG1942	4-Oxalocrotonate Tautomerase
AMBT_RS09680	COG1714	RDD family
AMBT_RS09710	COG0702	epimerase
AMBT_RS09720	COG0084	hydrolase, TatD family'
AMBT_RS09725	COG0470	DNA polymerase III
AMBT_RS09735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMBT_RS09740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMBT_RS09745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMBT_RS09750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMBT_RS09765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMBT_RS09770	COG0416	fatty acid biosynthetic process
AMBT_RS09780	COG1399	metal-binding, possibly nucleic acid-binding protein
AMBT_RS09785	COG0424	maF-like protein
AMBT_RS09790	COG0546	phosphoglycolate phosphatase activity
AMBT_RS09800	COG1530	ribonuclease E activity
AMBT_RS09820	COG2153	protein acetylation
AMBT_RS09840	COG0625	glutathione transferase activity
AMBT_RS09875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMBT_RS09885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMBT_RS09890	COG3724	N-succinylarginine dihydrolase activity
AMBT_RS09895	COG4932	domain protein
AMBT_RS09895	COG2373	Large extracellular alpha-helical protein
AMBT_RS09895	COG1388	LysM domain
AMBT_RS09900	COG1301	dicarboxylic acid transport
AMBT_RS09905	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMBT_RS09915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMBT_RS09950	COG0328	RNA-DNA hybrid ribonuclease activity
AMBT_RS09955	COG3321	synthase
AMBT_RS09955	COG0604	alcohol dehydrogenase
AMBT_RS09975	COG1643	Atp-dependent helicase
AMBT_RS10015	COG3437	response regulator, receiver
AMBT_RS10015	COG3850	Histidine kinase
AMBT_RS10015	COG2205	protein histidine kinase activity
AMBT_RS10015	COG4999	Histidine kinase
AMBT_RS10030	COG2925	Exonuclease
AMBT_RS10040	COG3706	GGDEF domain
AMBT_RS10045	COG0183	Belongs to the thiolase family
AMBT_RS10050	COG0789	Transcriptional regulator
AMBT_RS10055	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS10060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMBT_RS10065	COG1024	Enoyl-CoA hydratase
AMBT_RS10070	COG4770	biotin carboxylase activity
AMBT_RS10100	COG1957	nucleoside hydrolase
AMBT_RS10115	COG2814	Major facilitator Superfamily
AMBT_RS10150	COG0708	Exodeoxyribonuclease III
AMBT_RS10165	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMBT_RS10175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMBT_RS10185	COG2096	Adenosyltransferase
AMBT_RS10190	COG0471	metal ion transport
AMBT_RS10195	COG1472	Belongs to the glycosyl hydrolase 3 family
AMBT_RS10205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMBT_RS10230	COG0072	phenylalanine-tRNA ligase activity
AMBT_RS10230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMBT_RS10270	COG2246	polysaccharide biosynthetic process
AMBT_RS10275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMBT_RS10275	COG2755	lipolytic protein G-D-S-L family
AMBT_RS10280	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS10310	COG1216	Glycosyl transferase, family 2
AMBT_RS10355	COG0463	Glycosyl transferase, family 2
AMBT_RS10355	COG1216	Glycosyl transferase, family 2
AMBT_RS10360	COG1215	transferase activity, transferring glycosyl groups
AMBT_RS10375	COG1045	serine acetyltransferase
AMBT_RS10385	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS10420	COG4464	protein tyrosine phosphatase activity
AMBT_RS10425	COG0489	protein tyrosine kinase activity
AMBT_RS10430	COG1596	polysaccharide export
AMBT_RS10440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMBT_RS10460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMBT_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS10510	COG0730	response to heat
AMBT_RS10515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMBT_RS10535	COG2233	PERMEase
AMBT_RS10550	COG2205	protein histidine kinase activity
AMBT_RS10550	COG0784	Response regulator, receiver
AMBT_RS10560	COG3300	MHYT domain
AMBT_RS10560	COG5001	Diguanylate cyclase
AMBT_RS10570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMBT_RS10575	COG2252	PERMEase
AMBT_RS10590	COG1309	transcriptional regulator
AMBT_RS10600	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMBT_RS10615	COG2351	hydroxyisourate hydrolase activity
AMBT_RS10620	COG0402	S-adenosylhomocysteine deaminase activity
AMBT_RS10630	COG3447	MASE1 domain protein
AMBT_RS10630	COG5001	Diguanylate cyclase
AMBT_RS10630	COG5002	protein histidine kinase activity
AMBT_RS10635	COG2199	diguanylate cyclase activity
AMBT_RS10720	COG0740	serine-type endopeptidase activity
AMBT_RS10750	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMBT_RS10770	COG2211	Major facilitator Superfamily
AMBT_RS10770	COG2190	(PTS) system
AMBT_RS10775	COG1393	Belongs to the ArsC family
AMBT_RS10800	COG2988	succinylglutamate desuccinylase activity
AMBT_RS10810	COG0058	SHG alpha-glucan phosphorylase activity
AMBT_RS10815	COG0033	Phosphoglucomutase
AMBT_RS10820	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AMBT_RS10825	COG0714	Associated with various cellular activities
AMBT_RS10840	COG2116	formate transmembrane transporter activity
AMBT_RS10850	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AMBT_RS10855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMBT_RS10875	COG0583	DNA-binding transcription factor activity
AMBT_RS10885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMBT_RS10895	COG3437	response regulator, receiver
AMBT_RS10895	COG0784	Response regulator, receiver
AMBT_RS10900	COG2890	protein-(glutamine-N5) methyltransferase activity
AMBT_RS10910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMBT_RS10915	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AMBT_RS10920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMBT_RS10930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMBT_RS10935	COG5001	Diguanylate cyclase
AMBT_RS10945	COG1064	alcohol dehydrogenase
AMBT_RS10960	COG0012	GTP binding
AMBT_RS10965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMBT_RS10990	COG1115	amino acid carrier protein
AMBT_RS10995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMBT_RS11000	COG2755	lipolytic protein G-D-S-L family
AMBT_RS11000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMBT_RS11020	COG5433	transposase activity
AMBT_RS11035	COG0318	PFAM AMP-dependent synthetase and ligase
AMBT_RS11050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMBT_RS11055	COG1215	transferase activity, transferring glycosyl groups
AMBT_RS11060	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS11085	COG0489	protein tyrosine kinase activity
AMBT_RS11145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMBT_RS11155	COG1702	phosphate starvation-inducible protein PhoH
AMBT_RS11165	COG4535	Mg2 and Co2 transporter CorC
AMBT_RS11170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMBT_RS11175	COG0857	belongs to the CobB CobQ family
AMBT_RS11175	COG0280	phosphate acetyltransferase
AMBT_RS11185	COG0071	Belongs to the small heat shock protein (HSP20) family
AMBT_RS11215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMBT_RS11220	COG0505	Belongs to the CarA family
AMBT_RS11225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMBT_RS11245	COG3909	cytochrome
AMBT_RS11250	COG0484	heat shock protein binding
AMBT_RS11260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMBT_RS11265	COG2205	protein histidine kinase activity
AMBT_RS11265	COG3850	Histidine kinase
AMBT_RS11265	COG4999	Histidine kinase
AMBT_RS11265	COG3437	response regulator, receiver
AMBT_RS11280	COG2610	gluconate transmembrane transporter activity
AMBT_RS11285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMBT_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS11300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMBT_RS11310	COG0497	DNA recombination
AMBT_RS11315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMBT_RS11320	COG0500	methyltransferase
AMBT_RS11325	COG2733	membrane
AMBT_RS11340	COG0110	maltose O-acetyltransferase activity
AMBT_RS11350	COG0656	L-ascorbic acid biosynthetic process
AMBT_RS11365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMBT_RS11370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMBT_RS11375	COG0009	L-threonylcarbamoyladenylate synthase
AMBT_RS11380	COG0613	PHP domain protein
AMBT_RS11385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMBT_RS11395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMBT_RS11400	COG0135	phosphoribosylanthranilate isomerase activity
AMBT_RS11400	COG0134	indole-3-glycerol-phosphate synthase activity
AMBT_RS11410	COG0159	tryptophan synthase activity
AMBT_RS11415	COG2350	Protein conserved in bacteria
AMBT_RS11440	COG0628	permease
AMBT_RS11445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMBT_RS11450	COG1090	epimerase
AMBT_RS11455	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AMBT_RS11460	COG4181	ATPase activity
AMBT_RS11480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMBT_RS11520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMBT_RS11545	COG0745	RESPONSE REGULATOR receiver
AMBT_RS11555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMBT_RS11560	COG5265	(ABC) transporter
AMBT_RS11575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMBT_RS11580	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMBT_RS11585	COG4139	cobalamin transport
AMBT_RS11590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMBT_RS11605	COG2226	methyltransferase
AMBT_RS11610	COG0156	8-amino-7-oxononanoate synthase activity
AMBT_RS11635	COG0456	acetyltransferase
AMBT_RS11640	COG0189	ligase activity
AMBT_RS11655	COG0017	Asparaginyl-tRNA synthetase
AMBT_RS11665	COG2995	paraquat-inducible protein a
AMBT_RS11670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMBT_RS11670	COG3008	intermembrane lipid transfer
AMBT_RS11695	COG1309	transcriptional regulator
AMBT_RS11705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS11710	COG0517	IMP dehydrogenase activity
AMBT_RS11720	COG1063	alcohol dehydrogenase
AMBT_RS11730	COG3038	cytochrome b561
AMBT_RS11735	COG0753	catalase activity
AMBT_RS11740	COG4221	oxidoreductase activity
AMBT_RS11775	COG2271	Major facilitator Superfamily
AMBT_RS11855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMBT_RS11875	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AMBT_RS11880	COG2885	chlorophyll binding
AMBT_RS11885	COG0823	Involved in the tonB-independent uptake of proteins
AMBT_RS11900	COG0811	peptide transport
AMBT_RS11905	COG0824	Thioesterase
AMBT_RS11910	COG2255	four-way junction helicase activity
AMBT_RS11915	COG0632	four-way junction helicase activity
AMBT_RS11920	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMBT_RS11925	COG0494	nUDIX hydrolase
AMBT_RS11930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMBT_RS11945	COG2204	response regulator
AMBT_RS11955	COG2205	protein histidine kinase activity
AMBT_RS11985	COG0023	Translation Initiation Factor
AMBT_RS11990	COG0745	RESPONSE REGULATOR receiver
AMBT_RS11995	COG1605	Chorismate mutase
AMBT_RS11995	COG0077	Prephenate dehydratase
AMBT_RS12000	COG0287	Prephenate dehydrogenase
AMBT_RS12000	COG1605	Chorismate mutase
AMBT_RS12005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMBT_RS12010	COG2860	membrane
AMBT_RS12025	COG0335	large ribosomal subunit rRNA binding
AMBT_RS12030	COG0336	Belongs to the RNA methyltransferase TrmD family
AMBT_RS12035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMBT_RS12040	COG0228	four-way junction DNA binding
AMBT_RS12055	COG2873	o-acetylhomoserine
AMBT_RS12060	COG1132	(ABC) transporter
AMBT_RS12065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS12075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMBT_RS12105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMBT_RS12110	COG4137	Cytochrome C assembly protein
AMBT_RS12115	COG4536	flavin adenine dinucleotide binding
AMBT_RS12125	COG2062	phosphohistidine phosphatase, SixA
AMBT_RS12130	COG1025	Belongs to the peptidase M16 family
AMBT_RS12145	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMBT_RS12145	COG1024	Enoyl-CoA hydratase
AMBT_RS12155	COG0714	Associated with various cellular activities
AMBT_RS12175	COG2304	oxidoreductase activity
AMBT_RS12190	COG1595	DNA-templated transcription, initiation
AMBT_RS12205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMBT_RS12210	COG0175	sulfate reduction
AMBT_RS12215	COG0529	Catalyzes the synthesis of activated sulfate
AMBT_RS12230	COG3273	potassium ion transport
AMBT_RS12230	COG0471	metal ion transport
AMBT_RS12255	COG0367	asparagine synthase
AMBT_RS12265	COG0602	queuosine metabolic process
AMBT_RS12290	COG0556	nucleotide-excision repair
AMBT_RS12295	COG0534	Mate efflux family protein
AMBT_RS12310	COG4657	Part of a membrane complex involved in electron transport
AMBT_RS12315	COG2878	Part of a membrane complex involved in electron transport
AMBT_RS12320	COG4656	Part of a membrane complex involved in electron transport
AMBT_RS12325	COG4658	electron transport chain
AMBT_RS12330	COG4659	FMN binding
AMBT_RS12335	COG4660	Part of a membrane complex involved in electron transport
AMBT_RS12340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMBT_RS12350	COG0823	Involved in the tonB-independent uptake of proteins
AMBT_RS12350	COG4946	Tricorn protease homolog
AMBT_RS12350	COG1506	peptidase
AMBT_RS12370	COG1278	Cold shock
AMBT_RS12375	COG0346	lactoylglutathione lyase activity
AMBT_RS12380	COG0584	glycerophosphoryl diester phosphodiesterase
AMBT_RS12385	COG2885	chlorophyll binding
AMBT_RS12390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMBT_RS12395	COG0450	alkyl hydroperoxide reductase
AMBT_RS12420	COG4771	TonB-dependent receptor
AMBT_RS12425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMBT_RS12430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMBT_RS12435	COG2766	serine protein kinase
AMBT_RS12440	COG2718	Belongs to the UPF0229 family
AMBT_RS12445	COG2719	SpoVR family
AMBT_RS12465	COG2890	protein-(glutamine-N5) methyltransferase activity
AMBT_RS12485	COG1136	(ABC) transporter
AMBT_RS12485	COG0577	efflux transmembrane transporter activity
AMBT_RS12495	COG1136	(ABC) transporter
AMBT_RS12500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS12515	COG2918	glutathione biosynthetic process
AMBT_RS12520	COG0612	Peptidase, M16
AMBT_RS12530	COG0564	pseudouridine synthase activity
AMBT_RS12535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMBT_RS12540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMBT_RS12575	COG2175	clavaminate synthase activity
AMBT_RS12615	COG0583	DNA-binding transcription factor activity
AMBT_RS12620	COG5433	transposase activity
AMBT_RS12640	COG0456	acetyltransferase
AMBT_RS12690	COG1444	tRNA N-acetyltransferase activity
AMBT_RS12705	COG0848	biopolymer transport protein
AMBT_RS12710	COG0811	peptide transport
AMBT_RS12715	COG0811	peptide transport
AMBT_RS12775	COG1522	sequence-specific DNA binding
AMBT_RS12780	COG0625	glutathione transferase activity
AMBT_RS12795	COG3186	Phenylalanine-4-hydroxylase
AMBT_RS12810	COG1842	Phage shock protein A
AMBT_RS12815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMBT_RS12820	COG0747	negative chemotaxis
AMBT_RS12825	COG4168	peptide transport system, permease
AMBT_RS12830	COG4171	peptide transport system, permease
AMBT_RS12835	COG4172	Belongs to the ABC transporter superfamily
AMBT_RS12840	COG4172	Belongs to the ABC transporter superfamily
AMBT_RS12845	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AMBT_RS12885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMBT_RS12900	COG3590	peptidase
AMBT_RS12915	COG0659	secondary active sulfate transmembrane transporter activity
AMBT_RS12920	COG0288	reversible hydration of carbon dioxide
AMBT_RS12925	COG0583	DNA-binding transcription factor activity
AMBT_RS12930	COG0583	DNA-binding transcription factor activity
AMBT_RS12945	COG0646	methionine synthase
AMBT_RS12945	COG1410	methionine synthase
AMBT_RS12950	COG0646	methionine synthase
AMBT_RS12950	COG1410	methionine synthase
AMBT_RS12965	COG0835	chemotaxis
AMBT_RS12975	COG1192	Involved in chromosome partitioning
AMBT_RS12980	COG2201	protein-glutamate methylesterase activity
AMBT_RS12985	COG0643	Histidine kinase
AMBT_RS12985	COG0784	Response regulator, receiver
AMBT_RS12985	COG2198	Histidine kinase
AMBT_RS12990	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AMBT_RS13015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMBT_RS13030	COG1987	bacterial-type flagellum assembly
AMBT_RS13080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMBT_RS13085	COG1766	The M ring may be actively involved in energy transduction
AMBT_RS13115	COG1086	Polysaccharide biosynthesis protein
AMBT_RS13120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMBT_RS13125	COG1083	cytidylyl-transferase
AMBT_RS13135	COG2089	acid synthase
AMBT_RS13150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMBT_RS13170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMBT_RS13230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMBT_RS13235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMBT_RS13255	COG1256	bacterial-type flagellum assembly
AMBT_RS13260	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMBT_RS13260	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMBT_RS13280	COG4787	bacterial-type flagellum-dependent cell motility
AMBT_RS13285	COG1749	Flagellar hook protein flgE
AMBT_RS13300	COG1815	bacterial-type flagellum-dependent cell motility
AMBT_RS13305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMBT_RS13310	COG0835	chemotaxis
AMBT_RS13310	COG0784	Response regulator, receiver
AMBT_RS13350	COG2197	response regulator
AMBT_RS13355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS13360	COG2274	protein secretion by the type I secretion system
AMBT_RS13365	COG2885	chlorophyll binding
AMBT_RS13380	COG2840	Smr protein MutS2
AMBT_RS13385	COG0047	phosphoribosylformylglycinamidine synthase activity
AMBT_RS13385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMBT_RS13415	COG0037	tRNA processing
AMBT_RS13420	COG0825	malonyl-CoA metabolic process
AMBT_RS13425	COG0587	DNA-directed DNA polymerase activity
AMBT_RS13440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMBT_RS13445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMBT_RS13460	COG0750	zinc metalloprotease
AMBT_RS13465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMBT_RS13470	COG0575	Belongs to the CDS family
AMBT_RS13475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMBT_RS13485	COG0528	UMP kinase activity
AMBT_RS13495	COG0052	Belongs to the universal ribosomal protein uS2 family
AMBT_RS13500	COG0024	Methionine aminopeptidase
AMBT_RS13505	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMBT_RS13520	COG0564	pseudouridine synthase activity
AMBT_RS13585	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMBT_RS13585	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMBT_RS13595	COG1611	Belongs to the LOG family
AMBT_RS13610	COG0473	3-isopropylmalate dehydrogenase activity
AMBT_RS13615	COG1555	photosystem II stabilization
AMBT_RS13615	COG1596	polysaccharide export
AMBT_RS13620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMBT_RS13630	COG0463	Glycosyl transferase, family 2
AMBT_RS13630	COG1216	Glycosyl transferase, family 2
AMBT_RS13650	COG1682	transport, permease protein
AMBT_RS13675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMBT_RS13680	COG2853	Lipoprotein
AMBT_RS13695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMBT_RS13700	COG1138	Cytochrome C-type biogenesis protein
AMBT_RS13710	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMBT_RS13715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMBT_RS13720	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMBT_RS13725	COG4133	protoheme IX ABC transporter activity
AMBT_RS13740	COG1668	transmembrane transport
AMBT_RS13745	COG4555	ABC transporter
AMBT_RS13760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMBT_RS13790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMBT_RS13795	COG0473	3-isopropylmalate dehydrogenase activity
AMBT_RS13805	COG0066	3-isopropylmalate dehydratase activity
AMBT_RS13820	COG3409	Peptidoglycan-binding domain 1 protein
AMBT_RS13820	COG3267	Type II secretory pathway component ExeA
AMBT_RS13830	COG0513	Belongs to the DEAD box helicase family
AMBT_RS13840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMBT_RS13870	COG1346	cytolysis
AMBT_RS13910	COG1201	RNA secondary structure unwinding
AMBT_RS13975	COG4667	esterase of the alpha-beta hydrolase superfamily
AMBT_RS13990	COG5433	transposase activity
AMBT_RS14005	COG0488	(ABC) transporter
AMBT_RS14015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMBT_RS14020	COG2971	BadF BadG BcrA BcrD
AMBT_RS14030	COG3706	GGDEF domain
AMBT_RS14035	COG0419	ATPase involved in DNA repair
AMBT_RS14040	COG0420	3'-5' exonuclease activity
AMBT_RS14050	COG1739	Uncharacterized protein family UPF0029
AMBT_RS14065	COG1764	response to oxidative stress
AMBT_RS14070	COG1846	Transcriptional regulator
AMBT_RS14090	COG1272	protein, Hemolysin III
AMBT_RS14115	COG0583	DNA-binding transcription factor activity
AMBT_RS14125	COG0306	phosphate transporter
AMBT_RS14135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMBT_RS14140	COG0581	inorganic phosphate transmembrane transporter activity
AMBT_RS14145	COG0573	inorganic phosphate transmembrane transporter activity
AMBT_RS14155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMBT_RS14160	COG0248	Ppx GppA phosphatase
AMBT_RS14165	COG3588	fructose-bisphosphate aldolase
AMBT_RS14170	COG0126	phosphoglycerate kinase activity
AMBT_RS14180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMBT_RS14205	COG1979	alcohol dehydrogenase
AMBT_RS14210	COG2207	Transcriptional regulator
AMBT_RS14220	COG0784	Response regulator, receiver
AMBT_RS14220	COG2205	protein histidine kinase activity
AMBT_RS14240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMBT_RS14260	COG2207	Transcriptional regulator
AMBT_RS14265	COG2801	Transposase and inactivated derivatives
AMBT_RS14295	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMBT_RS14305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMBT_RS14315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMBT_RS14320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMBT_RS14330	COG5007	Belongs to the BolA IbaG family
AMBT_RS14335	COG3113	response to antibiotic
AMBT_RS14340	COG2854	intermembrane phospholipid transfer
AMBT_RS14345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMBT_RS14350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMBT_RS14355	COG1127	ABC transporter
AMBT_RS14370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMBT_RS14385	COG1137	ATPase activity
AMBT_RS14390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AMBT_RS14410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMBT_RS14415	COG2239	Acts as a magnesium transporter
AMBT_RS14435	COG2969	positive regulation of protein catabolic process
AMBT_RS14440	COG0625	glutathione transferase activity
AMBT_RS14445	COG2857	Cytochrome c1
AMBT_RS14450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMBT_RS14455	COG0723	plastoquinol--plastocyanin reductase activity
AMBT_RS14460	COG1473	amidohydrolase
AMBT_RS14470	COG4206	TonB-dependent receptor
AMBT_RS14480	COG1595	DNA-templated transcription, initiation
AMBT_RS14485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMBT_RS14505	COG3956	TIGRFAM MazG family protein
AMBT_RS14510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMBT_RS14515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMBT_RS14525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMBT_RS14545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMBT_RS14560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMBT_RS14565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMBT_RS14570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMBT_RS14575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMBT_RS14585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMBT_RS14590	COG0840	transmembrane signaling receptor activity
AMBT_RS14595	COG0527	aspartate kinase activity
AMBT_RS14615	COG1049	propionate catabolic process, 2-methylcitrate cycle
AMBT_RS14620	COG2133	pyrroloquinoline quinone binding
AMBT_RS14640	COG3437	response regulator, receiver
AMBT_RS14655	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AMBT_RS14660	COG0848	biopolymer transport protein
AMBT_RS14665	COG0811	peptide transport
AMBT_RS14670	COG0811	peptide transport
AMBT_RS14700	COG5002	protein histidine kinase activity
AMBT_RS14705	COG0745	RESPONSE REGULATOR receiver
AMBT_RS14710	COG4191	Histidine kinase
AMBT_RS14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMBT_RS14715	COG2974	May be involved in recombination
AMBT_RS14720	COG1396	sequence-specific DNA binding
AMBT_RS14725	COG3135	benzoate transporter
AMBT_RS14740	COG0537	adenosine 5'-monophosphoramidase activity
AMBT_RS14755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMBT_RS14760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMBT_RS14780	COG1610	YqeY-like protein
AMBT_RS14785	COG0358	DNA primase activity
AMBT_RS14810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS14815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS14830	COG4948	Mandelate Racemase Muconate Lactonizing
AMBT_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS14855	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS14870	COG0348	domain, Protein
AMBT_RS14875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMBT_RS14880	COG4206	TonB-dependent receptor
AMBT_RS14885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMBT_RS14900	COG1116	anion transmembrane transporter activity
AMBT_RS14905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMBT_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMBT_RS14910	COG1116	anion transmembrane transporter activity
AMBT_RS14925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMBT_RS14925	COG1648	precorrin-2 dehydrogenase activity
AMBT_RS14935	COG0243	molybdopterin cofactor binding
AMBT_RS14940	COG2146	nitrite reductase [NAD(P)H] activity
AMBT_RS14945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMBT_RS14950	COG0659	secondary active sulfate transmembrane transporter activity
AMBT_RS14960	COG3707	response regulator
AMBT_RS14970	COG0671	phosphoesterase, PA-phosphatase related
AMBT_RS14975	COG0271	Belongs to the BolA IbaG family
AMBT_RS14990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMBT_RS15015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMBT_RS15020	COG1509	lysine 2,3-aminomutase activity
AMBT_RS15040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMBT_RS15045	COG4251	negative regulation of phosphorylation
AMBT_RS15060	COG3150	esterase
AMBT_RS15075	COG0494	nUDIX hydrolase
AMBT_RS15080	COG1538	Outer membrane efflux protein
AMBT_RS15105	COG1648	precorrin-2 dehydrogenase activity
AMBT_RS15105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMBT_RS15115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMBT_RS15120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMBT_RS15125	COG0564	pseudouridine synthase activity
AMBT_RS15145	COG0784	Response regulator, receiver
AMBT_RS15145	COG5002	protein histidine kinase activity
AMBT_RS15150	COG3706	GGDEF domain
AMBT_RS15155	COG2201	protein-glutamate methylesterase activity
AMBT_RS15160	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMBT_RS15165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMBT_RS15170	COG0730	response to heat
AMBT_RS15175	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AMBT_RS15180	COG0494	nUDIX hydrolase
AMBT_RS15195	COG3025	triphosphatase activity
AMBT_RS15200	COG4991	sh3 domain protein
AMBT_RS15215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS15230	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AMBT_RS15230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AMBT_RS15230	COG0506	proline dehydrogenase activity
AMBT_RS15235	COG0840	transmembrane signaling receptor activity
AMBT_RS15245	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMBT_RS15260	COG0585	pseudouridine synthase activity
AMBT_RS15265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMBT_RS15275	COG1238	metal cluster binding
AMBT_RS15285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMBT_RS15315	COG0142	geranyltranstransferase activity
AMBT_RS15325	COG0006	proline dipeptidase activity
AMBT_RS15335	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMBT_RS15335	COG1024	Enoyl-CoA hydratase
AMBT_RS15340	COG0183	Belongs to the thiolase family
AMBT_RS15425	COG3547	Transposase (IS116 IS110 IS902 family)
AMBT_RS15490	COG0346	lactoylglutathione lyase activity
AMBT_RS15510	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AMBT_RS15515	COG3876	Protein conserved in bacteria
AMBT_RS15535	COG1757	Na H antiporter
AMBT_RS15550	COG1012	belongs to the aldehyde dehydrogenase family
AMBT_RS15560	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AMBT_RS15570	COG3118	belongs to the thioredoxin family
AMBT_RS15580	COG2133	pyrroloquinoline quinone binding
AMBT_RS15585	COG0783	Belongs to the Dps family
AMBT_RS15590	COG2847	Copper chaperone PCu(A)C
AMBT_RS15600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMBT_RS15605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMBT_RS15610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMBT_RS15615	COG0784	Response regulator, receiver
AMBT_RS15615	COG2205	protein histidine kinase activity
AMBT_RS15620	COG1473	amidohydrolase
AMBT_RS15625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMBT_RS15630	COG3118	belongs to the thioredoxin family
AMBT_RS15635	COG0513	Belongs to the DEAD box helicase family
AMBT_RS15640	COG0248	Ppx GppA phosphatase
AMBT_RS15655	COG0084	hydrolase, TatD family'
AMBT_RS15665	COG0805	protein transport
AMBT_RS15670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMBT_RS15690	COG0028	Belongs to the TPP enzyme family
AMBT_RS15705	COG0457	Tetratricopeptide repeat
AMBT_RS15725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMBT_RS15730	COG1162	GTPase activity
AMBT_RS15745	COG0584	glycerophosphoryl diester phosphodiesterase
AMBT_RS15755	COG2861	carbohydrate metabolic process
AMBT_RS15765	COG4942	peptidase
AMBT_RS15775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMBT_RS15790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMBT_RS15795	COG2267	carboxylic ester hydrolase activity
AMBT_RS15800	COG2205	protein histidine kinase activity
AMBT_RS15805	COG0745	RESPONSE REGULATOR receiver
AMBT_RS15820	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMBT_RS15830	COG1803	Methylglyoxal synthase
AMBT_RS15845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMBT_RS15850	COG0137	argininosuccinate synthase activity
AMBT_RS15860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMBT_RS15860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMBT_RS15865	COG5001	Diguanylate cyclase
AMBT_RS15865	COG3300	MHYT domain
AMBT_RS15890	COG0625	glutathione transferase activity
AMBT_RS15900	COG0281	malic enzyme
AMBT_RS15905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMBT_RS15940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMBT_RS15950	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AMBT_RS15970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMBT_RS15975	COG0180	Tryptophanyl-tRNA synthetase
AMBT_RS15990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMBT_RS15995	COG3138	arginine N-succinyltransferase
AMBT_RS16000	COG1012	belongs to the aldehyde dehydrogenase family
AMBT_RS16025	COG2205	protein histidine kinase activity
AMBT_RS16025	COG0784	Response regulator, receiver
AMBT_RS16025	COG5002	protein histidine kinase activity
AMBT_RS16040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS16050	COG0540	Belongs to the ATCase OTCase family
AMBT_RS16065	COG2837	iron assimilation
AMBT_RS16070	COG0405	Gamma-glutamyltransferase
AMBT_RS16075	COG0004	ammonium transporteR
AMBT_RS16095	COG2207	Transcriptional regulator
AMBT_RS16100	COG2354	Protein conserved in bacteria
AMBT_RS16110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMBT_RS16120	COG2951	lytic endotransglycosylase activity
AMBT_RS16175	COG1643	Atp-dependent helicase
AMBT_RS16185	COG0788	formyltetrahydrofolate deformylase activity
AMBT_RS16220	COG1519	Transferase
AMBT_RS16225	COG0859	PFAM glycosyl transferase family 9
AMBT_RS16230	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS16235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMBT_RS16250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMBT_RS16260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMBT_RS16270	COG0089	rRNA binding
AMBT_RS16285	COG0051	transcription antitermination factor activity, RNA binding
AMBT_RS16290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMBT_RS16310	COG1454	alcohol dehydrogenase
AMBT_RS16355	COG2211	Major facilitator Superfamily
AMBT_RS16365	COG0673	inositol 2-dehydrogenase activity
AMBT_RS16370	COG1609	Transcriptional regulator
AMBT_RS16435	COG0501	Belongs to the peptidase M48B family
AMBT_RS16450	COG2201	protein-glutamate methylesterase activity
AMBT_RS16455	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMBT_RS16470	COG0835	chemotaxis
AMBT_RS16475	COG0643	Histidine kinase
AMBT_RS16475	COG2198	Histidine kinase
AMBT_RS16480	COG0745	RESPONSE REGULATOR receiver
AMBT_RS16545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMBT_RS16560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMBT_RS16585	COG4974	Belongs to the 'phage' integrase family
AMBT_RS16590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMBT_RS16725	COG1484	DNA-dependent DNA replication
AMBT_RS16785	COG1194	a g-specific adenine glycosylase
AMBT_RS16795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMBT_RS16805	COG0297	glycogen (starch) synthase activity
AMBT_RS16810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMBT_RS16810	COG4191	Histidine kinase
AMBT_RS16815	COG0745	RESPONSE REGULATOR receiver
AMBT_RS16830	COG0312	modulator of DNA gyrase
AMBT_RS16835	COG3028	Belongs to the UPF0307 family
AMBT_RS16845	COG0312	modulator of DNA gyrase
AMBT_RS16850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMBT_RS16860	COG1530	ribonuclease E activity
AMBT_RS16870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AMBT_RS16875	COG1792	Involved in formation and maintenance of cell shape
AMBT_RS16880	COG1077	Cell shape determining protein MreB Mrl
AMBT_RS16910	COG2165	general secretion pathway protein
AMBT_RS16920	COG1459	type II secretion system
AMBT_RS16925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMBT_RS16935	COG3409	Peptidoglycan-binding domain 1 protein
AMBT_RS16935	COG3267	Type II secretory pathway component ExeA
AMBT_RS16975	COG1349	DNA-binding transcription factor activity
AMBT_RS16990	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMBT_RS17030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMBT_RS17045	COG0745	RESPONSE REGULATOR receiver
AMBT_RS17060	COG0629	single-stranded DNA binding
AMBT_RS17070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMBT_RS17075	COG1085	galactose-1-phosphate uridylyltransferase
AMBT_RS17095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMBT_RS17100	COG2814	Major facilitator Superfamily
AMBT_RS17105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMBT_RS17130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMBT_RS17140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMBT_RS17145	COG0163	prenyltransferase activity
AMBT_RS17175	COG0019	diaminopimelate decarboxylase activity
AMBT_RS17180	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMBT_RS17195	COG1011	Hydrolase
AMBT_RS17220	COG2239	Acts as a magnesium transporter
AMBT_RS17225	COG2050	protein possibly involved in aromatic compounds catabolism
AMBT_RS17230	COG0514	ATP-dependent DNA helicase (RecQ)
AMBT_RS17270	COG0629	single-stranded DNA binding
AMBT_RS17305	COG5654	RES domain protein
AMBT_RS17495	COG0077	Prephenate dehydratase
AMBT_RS17495	COG1605	Chorismate mutase
AMBT_RS17595	COG1802	Transcriptional regulator
AMBT_RS17600	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMBT_RS17610	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMBT_RS17615	COG3177	Filamentation induced by cAMP protein fic
AMBT_RS17630	COG1192	Involved in chromosome partitioning
AMBT_RS17655	COG0583	DNA-binding transcription factor activity
AMBT_RS17705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS17740	COG3077	Addiction module antitoxin, RelB DinJ family
AMBT_RS17745	COG2026	Addiction module toxin, RelE StbE family
AMBT_RS17750	COG0840	transmembrane signaling receptor activity
AMBT_RS17760	COG0625	glutathione transferase activity
AMBT_RS17765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMBT_RS17775	COG5001	Diguanylate cyclase
AMBT_RS17775	COG5002	protein histidine kinase activity
AMBT_RS17780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMBT_RS17785	COG3064	Membrane
AMBT_RS17795	COG0840	transmembrane signaling receptor activity
AMBT_RS17805	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMBT_RS17810	COG0427	acetyl-CoA hydrolase
AMBT_RS17820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS17825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS17860	COG3706	GGDEF domain
AMBT_RS17880	COG0668	transmembrane transport
AMBT_RS17895	COG2081	HI0933 family
AMBT_RS17900	COG3842	ATPase activity
AMBT_RS17905	COG1178	ABC-type Fe3 transport system permease component
AMBT_RS17920	COG0678	peroxiredoxin activity
AMBT_RS17920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMBT_RS17930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMBT_RS17935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMBT_RS17945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMBT_RS17955	COG0194	GDP metabolic process
AMBT_RS17970	COG0181	hydroxymethylbilane synthase activity
AMBT_RS17980	COG2959	enzyme of heme biosynthesis
AMBT_RS17985	COG3071	HemY protein
AMBT_RS17995	COG1953	Uracil, thiamine, allantoin
AMBT_RS18020	COG1309	transcriptional regulator
AMBT_RS18025	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMBT_RS18030	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMBT_RS18035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AMBT_RS18045	COG0778	Nitroreductase
AMBT_RS18045	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AMBT_RS18055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMBT_RS18060	COG4771	TonB-dependent receptor
AMBT_RS18090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMBT_RS18105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMBT_RS18125	COG3106	COG3106 Predicted ATPase
AMBT_RS18140	COG0583	DNA-binding transcription factor activity
AMBT_RS18145	COG1960	acyl-CoA dehydrogenase activity
AMBT_RS18155	COG0842	Transport permease protein
AMBT_RS18160	COG1129	ABC transporter
AMBT_RS18160	COG0842	Transport permease protein
AMBT_RS18165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMBT_RS18180	COG0583	DNA-binding transcription factor activity
AMBT_RS18185	COG4773	Receptor
AMBT_RS18195	COG1620	l-lactate permease
AMBT_RS18215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMBT_RS18225	COG1757	Na H antiporter
AMBT_RS18265	COG0210	DNA helicase
AMBT_RS18270	COG2960	long-chain fatty acid transporting porin activity
AMBT_RS18275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMBT_RS18280	COG3161	chorismate lyase activity
AMBT_RS18290	COG0705	Rhomboid family
AMBT_RS18295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMBT_RS18305	COG0156	8-amino-7-oxononanoate synthase activity
AMBT_RS18325	COG0859	PFAM glycosyl transferase family 9
AMBT_RS18330	COG3642	lipopolysaccharide core region biosynthetic process
AMBT_RS18370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMBT_RS18395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMBT_RS18410	COG2234	aminopeptidase activity
AMBT_RS18500	COG0583	DNA-binding transcription factor activity
AMBT_RS18525	COG1216	Glycosyl transferase, family 2
AMBT_RS18525	COG0438	transferase activity, transferring glycosyl groups
AMBT_RS18620	COG1216	Glycosyl transferase, family 2
AMBT_RS18620	COG0463	Glycosyl transferase, family 2
AMBT_RS18695	COG0202	RNA polymerase activity
AMBT_RS18715	COG0201	protein transport
AMBT_RS18735	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMBT_RS18770	COG5002	protein histidine kinase activity
AMBT_RS18770	COG0784	Response regulator, receiver
AMBT_RS18785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMBT_RS18790	COG0557	exoribonuclease II activity
AMBT_RS18800	COG4771	TonB-dependent receptor
AMBT_RS18805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AMBT_RS18820	COG0543	2 iron, 2 sulfur cluster binding
AMBT_RS18830	COG2234	aminopeptidase activity
AMBT_RS18850	COG1271	oxidase subunit
AMBT_RS18855	COG1294	oxidase, subunit
AMBT_RS18865	COG1522	sequence-specific DNA binding
AMBT_RS18880	COG1278	Cold shock
AMBT_RS18885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMBT_RS18905	COG0339	signal peptide processing
AMBT_RS18910	COG2201	protein-glutamate methylesterase activity
AMBT_RS18920	COG4191	Histidine kinase
AMBT_RS18920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMBT_RS18930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMBT_RS18935	COG0243	molybdopterin cofactor binding
AMBT_RS18940	COG4946	Tricorn protease homolog
AMBT_RS18940	COG0793	Belongs to the peptidase S41A family
AMBT_RS18960	COG2197	response regulator
AMBT_RS18980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMBT_RS18985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMBT_RS18990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMBT_RS19010	COG0281	malic enzyme
AMBT_RS19015	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AMBT_RS19020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMBT_RS19050	COG0456	acetyltransferase
AMBT_RS19060	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMBT_RS19065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMBT_RS19070	COG2177	Part of the ABC transporter FtsEX involved in
AMBT_RS19075	COG2884	Cell division ATP-binding protein ftsE
AMBT_RS19080	COG0552	protein localization to endoplasmic reticulum
AMBT_RS19085	COG0742	ribosomal rna small subunit methyltransferase
AMBT_RS19095	COG2095	MarC family integral membrane protein
AMBT_RS19115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMBT_RS19120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMBT_RS19130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMBT_RS19145	COG0076	glutamate decarboxylase activity
AMBT_RS19160	COG0842	Transport permease protein
AMBT_RS19165	COG1131	(ABC) transporter
AMBT_RS19170	COG0745	RESPONSE REGULATOR receiver
AMBT_RS19175	COG2205	protein histidine kinase activity
AMBT_RS19180	COG4774	siderophore transport
AMBT_RS19200	COG1253	flavin adenine dinucleotide binding
AMBT_RS19205	COG0701	Predicted permease
AMBT_RS19210	COG1966	Carbon starvation protein
AMBT_RS19225	COG0657	acetylesterase activity
AMBT_RS19240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMBT_RS19245	COG0049	tRNA binding
AMBT_RS19250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMBT_RS19255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMBT_RS19260	COG0085	RNA polymerase activity
AMBT_RS19265	COG0222	ribosome binding
AMBT_RS19270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMBT_RS19275	COG0081	regulation of translation
AMBT_RS19280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMBT_RS19285	COG0250	Participates in transcription elongation, termination and antitermination
AMBT_RS19290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMBT_RS19300	COG1132	(ABC) transporter
AMBT_RS19305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMBT_RS19310	COG3590	peptidase
AMBT_RS19320	COG0513	Belongs to the DEAD box helicase family
AMBT_RS19325	COG0418	dihydroorotase activity
AMBT_RS19335	COG3040	lipid binding
AMBT_RS19340	COG4989	oxidoreductase activity
AMBT_RS19345	COG0346	lactoylglutathione lyase activity
AMBT_RS19355	COG0302	gtp cyclohydrolase
AMBT_RS19360	COG2957	Belongs to the agmatine deiminase family
AMBT_RS19365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMBT_RS19375	COG1201	RNA secondary structure unwinding
AMBT_RS19395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMBT_RS19405	COG1410	methionine synthase
AMBT_RS19405	COG0646	methionine synthase
AMBT_RS19410	COG0625	glutathione transferase activity
AMBT_RS19425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMBT_RS19430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMBT_RS19440	COG1012	belongs to the aldehyde dehydrogenase family
AMBT_RS19455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMBT_RS19460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AMBT_RS19465	COG0330	HflC and HflK could
AMBT_RS19470	COG0330	HflC and HflK could
AMBT_RS19475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMBT_RS19480	COG1923	regulation of RNA biosynthetic process
AMBT_RS19485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMBT_RS19500	COG0802	atpase or kinase
AMBT_RS19505	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMBT_RS19505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMBT_RS19525	COG2816	NAD+ diphosphatase activity
AMBT_RS19530	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AMBT_RS19535	COG0735	belongs to the Fur family
AMBT_RS19555	COG0305	Participates in initiation and elongation during chromosome replication
AMBT_RS19580	COG2258	MOSC domain
AMBT_RS19610	COG5002	protein histidine kinase activity
AMBT_RS19620	COG0840	transmembrane signaling receptor activity
AMBT_RS19625	COG4191	Histidine kinase
AMBT_RS19625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMBT_RS19635	COG1609	Transcriptional regulator
AMBT_RS19640	COG2211	Major facilitator Superfamily
AMBT_RS19660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMBT_RS19665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMBT_RS19670	COG4558	Periplasmic binding protein
AMBT_RS19680	COG4206	TonB-dependent receptor
AMBT_RS19690	COG1472	Belongs to the glycosyl hydrolase 3 family
AMBT_RS19705	COG2855	membrane
AMBT_RS19710	COG2175	clavaminate synthase activity
AMBT_RS19715	COG0656	L-ascorbic acid biosynthetic process
AMBT_RS19720	COG2188	Transcriptional regulator
AMBT_RS19735	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMBT_RS19775	COG4771	TonB-dependent receptor
AMBT_RS19780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMBT_RS19785	COG4988	ABC transporter
AMBT_RS19795	COG1294	oxidase, subunit
AMBT_RS19810	COG2204	response regulator
AMBT_RS19840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMBT_RS19875	COG4319	ketosteroid isomerase
AMBT_RS19920	COG3237	CsbD-like
AMBT_RS19940	COG1404	Belongs to the peptidase S8 family
AMBT_RS19965	COG2267	carboxylic ester hydrolase activity
AMBT_RS19990	COG3038	cytochrome b561
AMBT_RS19995	COG2353	YceI-like domain
AMBT_RS20000	COG1252	NADH dehydrogenase
AMBT_RS20025	COG2067	long-chain fatty acid transport protein
AMBT_RS20030	COG2130	NADP-dependent
AMBT_RS20035	COG4251	negative regulation of phosphorylation
AMBT_RS20035	COG5001	Diguanylate cyclase
AMBT_RS20035	COG2203	Gaf domain
AMBT_RS20035	COG3706	GGDEF domain
AMBT_RS20055	COG3293	Transposase
AMBT_RS20060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMBT_RS20070	COG4181	ATPase activity
AMBT_RS20090	COG0523	cobalamin synthesis protein
AMBT_RS20105	COG4771	TonB-dependent receptor
AMBT_RS20130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMBT_RS20150	COG0697	spore germination
AMBT_RS20155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMBT_RS20170	COG1166	arginine decarboxylase activity
AMBT_RS20180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMBT_RS20205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMBT_RS20215	COG0830	nickel cation binding
AMBT_RS20240	COG0829	nickel cation binding
AMBT_RS20280	COG0745	RESPONSE REGULATOR receiver
AMBT_RS20285	COG0523	cobalamin synthesis protein
AMBT_RS20360	COG2003	Belongs to the UPF0758 family
AMBT_RS20460	COG0084	hydrolase, TatD family'
AMBT_RS20470	COG0786	glutamate:sodium symporter activity
AMBT_RS20480	COG1538	Outer membrane efflux protein
AMBT_RS20560	COG1475	DNA binding
AMBT_RS20570	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AMBT_RS20595	COG4232	protein-disulfide reductase activity
AMBT_RS20600	COG0739	heme binding
AMBT_RS20605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMBT_RS20610	COG0511	ligase activity, forming carbon-carbon bonds
AMBT_RS20615	COG0439	Biotin carboxylase
AMBT_RS20635	COG2176	DNA-directed DNA polymerase activity
AMBT_RS20655	COG0154	amidase activity
AMBT_RS20690	COG3038	cytochrome b561
AMBT_RS20695	COG0667	Aldo Keto reductase
AMBT_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
AMBT_RS20705	COG3384	dioxygenase
AMBT_RS20710	COG0583	DNA-binding transcription factor activity
AMBT_RS20715	COG1484	DNA-dependent DNA replication
AMBT_RS20735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMBT_RS20740	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AMBT_RS20755	COG0151	Belongs to the GarS family
AMBT_RS20765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMBT_RS20770	COG3954	Phosphoribulokinase
AMBT_RS20780	COG2963	transposase activity
AMBT_RS20785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMBT_RS20795	COG1309	transcriptional regulator
AMBT_RS20810	COG0745	RESPONSE REGULATOR receiver
AMBT_RS20820	COG0318	PFAM AMP-dependent synthetase and ligase
AMBT_RS20825	COG5433	transposase activity
AMBT_RS20845	COG5433	transposase activity
AMBT_RS20910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMBT_RS20915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMBT_RS20925	COG3031	protein transport across the cell outer membrane
AMBT_RS20935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMBT_RS20940	COG1459	type II secretion system
AMBT_RS20945	COG2165	general secretion pathway protein
AMBT_RS20950	COG2165	general secretion pathway protein
AMBT_RS20955	COG2165	general secretion pathway protein
AMBT_RS20960	COG4795	General secretion pathway protein
AMBT_RS20975	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AMBT_RS20985	COG1234	tRNA 3'-trailer cleavage
AMBT_RS20990	COG1012	belongs to the aldehyde dehydrogenase family
AMBT_RS20995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AMBT_RS21000	COG1011	Hydrolase
AMBT_RS21005	COG0494	nUDIX hydrolase
AMBT_RS21010	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMBT_RS21020	COG2943	transferase activity, transferring hexosyl groups
AMBT_RS21025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AMBT_RS21040	COG3089	Belongs to the UPF0270 family
AMBT_RS21045	COG0429	hydrolase of the alpha beta-hydrolase fold
AMBT_RS21055	COG0488	(ABC) transporter
AMBT_RS21060	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AMBT_RS21080	COG0545	Peptidyl-prolyl cis-trans isomerase
AMBT_RS21140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMBT_RS21165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMBT_RS21170	COG2183	response to ionizing radiation
AMBT_RS21185	COG0596	Alpha beta hydrolase
AMBT_RS21190	COG1040	competence protein
AMBT_RS21210	COG1794	racemase activity, acting on amino acids and derivatives
AMBT_RS21220	COG2226	methyltransferase
AMBT_RS21225	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AMBT_RS21230	COG0534	Mate efflux family protein
AMBT_RS21245	COG1999	signal sequence binding
AMBT_RS21250	COG0109	protoheme IX farnesyltransferase activity
AMBT_RS21255	COG1612	heme a metabolic process
AMBT_RS21280	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AMBT_RS21285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMBT_RS21290	COG1565	acr, cog1565
AMBT_RS21290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMBT_RS21320	COG0129	dihydroxy-acid dehydratase activity
AMBT_RS21335	COG0606	chelatase, subunit chli
AMBT_RS21350	COG2814	Major facilitator Superfamily
AMBT_RS21355	COG1073	alpha beta
AMBT_RS21360	COG0729	surface antigen
AMBT_RS21365	COG2911	Protein conserved in bacteria
AMBT_RS21390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMBT_RS21400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMBT_RS21420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMBT_RS21470	COG0425	Belongs to the sulfur carrier protein TusA family
AMBT_RS21485	COG1561	YicC-like family, N-terminal region
AMBT_RS21625	COG2211	Major facilitator Superfamily
AMBT_RS21630	COG1609	Transcriptional regulator
AMBT_RS21645	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMBT_RS21645	COG2199	diguanylate cyclase activity
AMBT_RS21660	COG0625	glutathione transferase activity
AMBT_RS21675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMBT_RS21695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMBT_RS21700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMBT_RS21720	COG1475	DNA binding
AMBT_RS21725	COG1192	Involved in chromosome partitioning
AMBT_RS21750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMBT_RS21755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMBT_RS21765	COG0706	membrane insertase activity
AMBT_RS21770	COG0594	ribonuclease P activity
AMBT_RS21785	COG4771	TonB-dependent receptor
AMBT_RS21805	COG1357	PFAM Pentapeptide repeats (8 copies)
AMBT_RS21805	COG0515	serine threonine protein kinase
AMBT_RS21835	COG4795	General secretion pathway protein
AMBT_RS21865	COG0746	molybdenum cofactor guanylyltransferase activity
AMBT_RS21870	COG0784	Response regulator, receiver
AMBT_RS21870	COG5002	protein histidine kinase activity
AMBT_RS21870	COG2205	protein histidine kinase activity
AMBT_RS21880	COG0596	Alpha beta hydrolase
AMBT_RS21930	COG3706	GGDEF domain
AMBT_RS21935	COG1595	DNA-templated transcription, initiation
AMBT_RS21960	COG2226	methyltransferase