locus-tag	class	description
AOR13_RS00010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOR13_RS00015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AOR13_RS00015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AOR13_RS00020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AOR13_RS00055	COG0753	catalase activity
AOR13_RS00070	COG0667	Aldo Keto reductase
AOR13_RS00075	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOR13_RS00090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOR13_RS00105	COG0189	ligase activity
AOR13_RS00105	COG4067	protein conserved in archaea
AOR13_RS00115	COG0189	ligase activity
AOR13_RS00135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_RS00140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOR13_RS00140	COG0517	IMP dehydrogenase activity
AOR13_RS00160	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOR13_RS00165	COG0457	Tetratricopeptide repeat
AOR13_RS00175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOR13_RS00180	COG0572	uridine kinase
AOR13_RS00210	COG1438	arginine binding
AOR13_RS00215	COG0039	L-malate dehydrogenase activity
AOR13_RS00225	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AOR13_RS00230	COG0545	Peptidyl-prolyl cis-trans isomerase
AOR13_RS00235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOR13_RS00240	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_RS00245	COG1805	sodium ion transport
AOR13_RS00250	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_RS00255	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_RS00260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_RS00265	COG2871	sodium ion transport
AOR13_RS00270	COG1477	protein flavinylation
AOR13_RS00280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOR13_RS00290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_RS00305	COG1522	sequence-specific DNA binding
AOR13_RS00320	COG0121	glutamine amidotransferase
AOR13_RS00325	COG0583	DNA-binding transcription factor activity
AOR13_RS00335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_RS00340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOR13_RS00350	COG5002	protein histidine kinase activity
AOR13_RS00350	COG5001	Diguanylate cyclase
AOR13_RS00365	COG0702	epimerase
AOR13_RS00370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AOR13_RS00400	COG0457	Tetratricopeptide repeat
AOR13_RS00410	COG0848	biopolymer transport protein
AOR13_RS00435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOR13_RS00450	COG0733	neurotransmitter:sodium symporter activity
AOR13_RS00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOR13_RS00470	COG0668	transmembrane transport
AOR13_RS00475	COG0204	Acyl-transferase
AOR13_RS00480	COG0204	Acyl-transferase
AOR13_RS00485	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOR13_RS00510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_RS00520	COG1842	Phage shock protein A
AOR13_RS00545	COG4771	TonB-dependent receptor
AOR13_RS00550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOR13_RS00570	COG5001	Diguanylate cyclase
AOR13_RS00570	COG3300	MHYT domain
AOR13_RS00575	COG1573	uracil-dna glycosylase
AOR13_RS00585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_RS00600	COG1309	transcriptional regulator
AOR13_RS00645	COG0417	DNA replication proofreading
AOR13_RS00655	COG4191	Histidine kinase
AOR13_RS00670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOR13_RS00675	COG0730	response to heat
AOR13_RS00690	COG3568	Endonuclease Exonuclease Phosphatase
AOR13_RS00725	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOR13_RS00725	COG3264	Mechanosensitive ion channel
AOR13_RS00735	COG2186	Transcriptional regulator
AOR13_RS00740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_RS00745	COG0800	Aldolase
AOR13_RS00750	COG0513	Belongs to the DEAD box helicase family
AOR13_RS00755	COG1716	ATPase activity
AOR13_RS00755	COG0842	Transport permease protein
AOR13_RS00755	COG1131	(ABC) transporter
AOR13_RS00770	COG1357	PFAM Pentapeptide repeats (8 copies)
AOR13_RS00770	COG0515	serine threonine protein kinase
AOR13_RS00805	COG1716	ATPase activity
AOR13_RS00825	COG2271	Major facilitator Superfamily
AOR13_RS00830	COG1917	Cupin 2, conserved barrel domain protein
AOR13_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS00870	COG1858	cytochrome C peroxidase
AOR13_RS00875	COG4771	TonB-dependent receptor
AOR13_RS00905	COG4585	Histidine kinase
AOR13_RS00910	COG2197	response regulator
AOR13_RS00920	COG3901	Regulator of nitric oxide reductase transcription
AOR13_RS00920	COG0348	domain, Protein
AOR13_RS00930	COG0784	Response regulator, receiver
AOR13_RS00930	COG2205	protein histidine kinase activity
AOR13_RS00960	COG0535	radical SAM domain protein
AOR13_RS00970	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AOR13_RS00975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOR13_RS00980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOR13_RS01020	COG3706	GGDEF domain
AOR13_RS01025	COG3706	GGDEF domain
AOR13_RS01045	COG0395	ABC-type sugar transport system, permease component
AOR13_RS01055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_RS01125	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOR13_RS01205	COG1082	Xylose isomerase domain protein TIM barrel
AOR13_RS01270	COG0795	lipopolysaccharide-transporting ATPase activity
AOR13_RS01275	COG0795	lipopolysaccharide-transporting ATPase activity
AOR13_RS01280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOR13_RS01285	COG2927	DNA polymerase III (CHI subunit)
AOR13_RS01290	COG0525	valine-tRNA ligase activity
AOR13_RS01325	COG3437	response regulator, receiver
AOR13_RS01335	COG3852	Histidine kinase
AOR13_RS01345	COG0174	glutamine synthetase
AOR13_RS01350	COG1217	gtp-binding protein TYPA
AOR13_RS01360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOR13_RS01365	COG1914	H( )-stimulated, divalent metal cation uptake system
AOR13_RS01380	COG1981	membrane
AOR13_RS01405	COG0850	regulation of cytokinetic process
AOR13_RS01410	COG2894	cell division
AOR13_RS01430	COG0625	glutathione transferase activity
AOR13_RS01435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_RS01445	COG1902	pentaerythritol trinitrate reductase activity
AOR13_RS01450	COG3659	wide pore channel activity
AOR13_RS01455	COG0738	Major facilitator superfamily
AOR13_RS01465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOR13_RS01470	COG0739	heme binding
AOR13_RS01475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOR13_RS01490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOR13_RS01495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOR13_RS01505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOR13_RS01545	COG1476	TRANSCRIPTIONal
AOR13_RS01555	COG0493	'glutamate synthase
AOR13_RS01560	COG0070	glutamate synthase
AOR13_RS01560	COG0067	glutamate synthase
AOR13_RS01560	COG0069	glutamate synthase activity
AOR13_RS01565	COG2198	Histidine kinase
AOR13_RS01565	COG0784	Response regulator, receiver
AOR13_RS01565	COG5002	protein histidine kinase activity
AOR13_RS01585	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AOR13_RS01610	COG3706	GGDEF domain
AOR13_RS01615	COG2828	Protein conserved in bacteria
AOR13_RS01625	COG0372	Belongs to the citrate synthase family
AOR13_RS01635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOR13_RS01645	COG4771	TonB-dependent receptor
AOR13_RS01650	COG2197	response regulator
AOR13_RS01655	COG4585	Histidine kinase
AOR13_RS01700	COG2823	Periplasmic or secreted lipoprotein
AOR13_RS01710	COG0792	nuclease activity
AOR13_RS01715	COG3107	peptidoglycan biosynthetic process
AOR13_RS01720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOR13_RS01735	COG1748	Saccharopine dehydrogenase
AOR13_RS01760	COG5002	protein histidine kinase activity
AOR13_RS01765	COG0745	RESPONSE REGULATOR receiver
AOR13_RS01770	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AOR13_RS01775	COG2201	protein-glutamate methylesterase activity
AOR13_RS01780	COG0798	PFAM Bile acid sodium symporter
AOR13_RS01785	COG0431	NADPH-dependent FMN reductase
AOR13_RS01795	COG0640	Transcriptional regulator
AOR13_RS01815	COG4585	Histidine kinase
AOR13_RS01820	COG2197	response regulator
AOR13_RS01830	COG0583	DNA-binding transcription factor activity
AOR13_RS01840	COG0083	homoserine kinase activity
AOR13_RS01870	COG0625	glutathione transferase activity
AOR13_RS01875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS01890	COG1902	pentaerythritol trinitrate reductase activity
AOR13_RS01890	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_RS01905	COG0762	integral membrane protein
AOR13_RS01910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOR13_RS01915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOR13_RS01935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOR13_RS01940	COG1678	Uncharacterized ACR, COG1678
AOR13_RS01945	COG0189	ligase activity
AOR13_RS01950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOR13_RS01955	COG0668	transmembrane transport
AOR13_RS01975	COG0784	Response regulator, receiver
AOR13_RS01975	COG2198	Histidine kinase
AOR13_RS01975	COG5002	protein histidine kinase activity
AOR13_RS01980	COG2204	response regulator
AOR13_RS01995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_RS01995	COG0678	peroxiredoxin activity
AOR13_RS02035	COG2001	Belongs to the MraZ family
AOR13_RS02045	COG3116	cell division
AOR13_RS02050	COG0768	penicillin binding
AOR13_RS02055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOR13_RS02060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOR13_RS02070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOR13_RS02075	COG0772	Belongs to the SEDS family
AOR13_RS02085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOR13_RS02090	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOR13_RS02095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOR13_RS02100	COG0849	cell division
AOR13_RS02110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AOR13_RS02115	COG0739	heme binding
AOR13_RS02125	COG0494	nUDIX hydrolase
AOR13_RS02130	COG2988	succinylglutamate desuccinylase activity
AOR13_RS02135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOR13_RS02140	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AOR13_RS02145	COG0237	dephospho-CoA kinase activity
AOR13_RS02145	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOR13_RS02155	COG1459	type II secretion system
AOR13_RS02160	COG4969	Belongs to the N-Me-Phe pilin family
AOR13_RS02190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOR13_RS02195	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_RS02200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_RS02240	COG3313	Fe-S protein
AOR13_RS02260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_RS02265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOR13_RS02270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOR13_RS02285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_RS02295	COG0006	proline dipeptidase activity
AOR13_RS02300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_RS02305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_RS02330	COG1629	transport
AOR13_RS02340	COG0477	Major facilitator Superfamily
AOR13_RS02345	COG1621	beta-fructofuranosidase activity
AOR13_RS02365	COG0583	DNA-binding transcription factor activity
AOR13_RS02380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOR13_RS02380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOR13_RS02410	COG2801	Transposase and inactivated derivatives
AOR13_RS02435	COG0656	L-ascorbic acid biosynthetic process
AOR13_RS02445	COG2814	Major facilitator Superfamily
AOR13_RS02495	COG0513	Belongs to the DEAD box helicase family
AOR13_RS02500	COG0697	spore germination
AOR13_RS02510	COG2133	pyrroloquinoline quinone binding
AOR13_RS02530	COG1757	Na H antiporter
AOR13_RS02545	COG0653	protein targeting
AOR13_RS02560	COG1451	nucleotide metabolic process
AOR13_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOR13_RS02595	COG2319	Wd-40 repeat
AOR13_RS02595	COG4249	Peptidase C14 caspase catalytic subunit p20
AOR13_RS02620	COG3604	Transcriptional regulator
AOR13_RS02635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOR13_RS02635	COG1017	nitric oxide dioxygenase activity
AOR13_RS02640	COG0484	heat shock protein binding
AOR13_RS02650	COG0583	DNA-binding transcription factor activity
AOR13_RS02675	COG0514	ATP-dependent DNA helicase (RecQ)
AOR13_RS02685	COG1295	ribonuclease BN
AOR13_RS02695	COG1846	Transcriptional regulator
AOR13_RS02700	COG1566	PFAM secretion protein HlyD family protein
AOR13_RS02735	COG4771	TonB-dependent receptor
AOR13_RS02755	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AOR13_RS02760	COG1335	isochorismatase
AOR13_RS02765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOR13_RS02790	COG2801	Transposase and inactivated derivatives
AOR13_RS02800	COG0789	Transcriptional regulator
AOR13_RS02865	COG0693	protein deglycase activity
AOR13_RS02870	COG4221	oxidoreductase activity
AOR13_RS02885	COG0583	DNA-binding transcription factor activity
AOR13_RS02900	COG0109	protoheme IX farnesyltransferase activity
AOR13_RS02915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOR13_RS02920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOR13_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS02965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOR13_RS02980	COG1733	regulation of RNA biosynthetic process
AOR13_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS03000	COG0583	DNA-binding transcription factor activity
AOR13_RS03065	COG0826	peptidase U32
AOR13_RS03070	COG1607	acyl-coa hydrolase
AOR13_RS03120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOR13_RS03130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOR13_RS03160	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS03215	COG0189	ligase activity
AOR13_RS03230	COG0789	Transcriptional regulator
AOR13_RS03235	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AOR13_RS03250	COG4682	membrane
AOR13_RS03255	COG1629	transport
AOR13_RS03255	COG4774	siderophore transport
AOR13_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS03285	COG4774	siderophore transport
AOR13_RS03310	COG1982	Orn Lys Arg decarboxylase major
AOR13_RS03320	COG0515	serine threonine protein kinase
AOR13_RS03320	COG2815	serine threonine protein kinase
AOR13_RS03345	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AOR13_RS03350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOR13_RS03355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOR13_RS03360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOR13_RS03400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOR13_RS03405	COG1609	Transcriptional regulator
AOR13_RS03415	COG1435	thymidine kinase activity
AOR13_RS03430	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS03460	COG1560	Kdo2-lipid A biosynthetic process
AOR13_RS03480	COG2827	Endonuclease containing a URI domain
AOR13_RS03485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AOR13_RS03485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AOR13_RS03490	COG3267	Type II secretory pathway component ExeA
AOR13_RS03490	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_RS03500	COG0489	protein tyrosine kinase activity
AOR13_RS03535	COG1216	Glycosyl transferase, family 2
AOR13_RS03535	COG0463	Glycosyl transferase, family 2
AOR13_RS03580	COG0438	transferase activity, transferring glycosyl groups
AOR13_RS03605	COG1045	serine acetyltransferase
AOR13_RS03610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOR13_RS03660	COG0745	RESPONSE REGULATOR receiver
AOR13_RS03665	COG1785	Belongs to the alkaline phosphatase family
AOR13_RS03670	COG2066	Belongs to the glutaminase family
AOR13_RS03685	COG0754	glutathionylspermidine amidase activity
AOR13_RS03710	COG1842	Phage shock protein A
AOR13_RS03715	COG3789	protein conserved in bacteria
AOR13_RS03730	COG0343	queuine tRNA-ribosyltransferase activity
AOR13_RS03735	COG1862	Preprotein translocase
AOR13_RS03740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_RS03745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_RS03775	COG0483	inositol monophosphate 1-phosphatase activity
AOR13_RS03780	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AOR13_RS03795	COG1104	cysteine desulfurase activity
AOR13_RS03800	COG0719	Fe-S assembly protein
AOR13_RS03805	COG0396	ATPase activity
AOR13_RS03810	COG0719	Fe-S assembly protein
AOR13_RS03815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOR13_RS03830	COG2166	iron-sulfur cluster assembly
AOR13_RS03840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOR13_RS03865	COG2976	Protein conserved in bacteria
AOR13_RS03870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_RS03885	COG1570	exodeoxyribonuclease VII activity
AOR13_RS03890	COG0517	IMP dehydrogenase activity
AOR13_RS03890	COG0516	GMP reductase activity
AOR13_RS03910	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOR13_RS03930	COG1720	tRNA m6t6A37 methyltransferase activity
AOR13_RS03970	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOR13_RS03975	COG0740	serine-type endopeptidase activity
AOR13_RS03980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOR13_RS03985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOR13_RS03990	COG0776	regulation of translation
AOR13_RS03995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_RS04020	COG0385	Bile acid
AOR13_RS04040	COG0268	Binds directly to 16S ribosomal RNA
AOR13_RS04045	COG0728	peptidoglycan biosynthetic process
AOR13_RS04050	COG0196	riboflavin kinase activity
AOR13_RS04055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOR13_RS04065	COG1047	Peptidyl-prolyl cis-trans
AOR13_RS04070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOR13_RS04130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOR13_RS04150	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOR13_RS04165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOR13_RS04170	COG1595	DNA-templated transcription, initiation
AOR13_RS04215	COG0084	hydrolase, TatD family'
AOR13_RS04225	COG0560	Phosphoserine phosphatase
AOR13_RS04235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOR13_RS04245	COG0488	(ABC) transporter
AOR13_RS04250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOR13_RS04265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOR13_RS04265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOR13_RS04280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOR13_RS04290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOR13_RS04295	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOR13_RS04305	COG0142	geranyltranstransferase activity
AOR13_RS04310	COG1722	exodeoxyribonuclease VII activity
AOR13_RS04315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOR13_RS04325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOR13_RS04335	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOR13_RS04340	COG4221	oxidoreductase activity
AOR13_RS04355	COG1595	DNA-templated transcription, initiation
AOR13_RS04370	COG0564	pseudouridine synthase activity
AOR13_RS04375	COG1496	oxidoreductase activity
AOR13_RS04380	COG0542	response to heat
AOR13_RS04400	COG1183	phosphatidylcholine synthase activity
AOR13_RS04430	COG4251	negative regulation of phosphorylation
AOR13_RS04430	COG5001	Diguanylate cyclase
AOR13_RS04430	COG3706	GGDEF domain
AOR13_RS04430	COG2203	Gaf domain
AOR13_RS04445	COG2319	Wd-40 repeat
AOR13_RS04445	COG4249	Peptidase C14 caspase catalytic subunit p20
AOR13_RS04455	COG3220	belongs to the UPF0276 family
AOR13_RS04465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOR13_RS04470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOR13_RS04495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOR13_RS04500	COG0326	Molecular chaperone. Has ATPase activity
AOR13_RS04525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_RS04535	COG0642	Histidine kinase
AOR13_RS04555	COG0463	Glycosyl transferase, family 2
AOR13_RS04575	COG1022	Amp-dependent synthetase and ligase
AOR13_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS04595	COG0140	phosphoribosyl-ATP diphosphatase activity
AOR13_RS04595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOR13_RS04610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOR13_RS04615	COG0131	Imidazoleglycerol-phosphate dehydratase
AOR13_RS04615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOR13_RS04620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOR13_RS04625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOR13_RS04630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOR13_RS04685	COG1199	ATP-dependent helicase activity
AOR13_RS04690	COG1214	PFAM Peptidase M22, glycoprotease
AOR13_RS04705	COG2267	carboxylic ester hydrolase activity
AOR13_RS04710	COG0318	PFAM AMP-dependent synthetase and ligase
AOR13_RS04715	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOR13_RS04730	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOR13_RS04735	COG2983	Belongs to the UPF0260 family
AOR13_RS04740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOR13_RS04745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AOR13_RS04755	COG2186	Transcriptional regulator
AOR13_RS04790	COG4399	Belongs to the UPF0754 family
AOR13_RS04795	COG1309	transcriptional regulator
AOR13_RS04800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_RS04825	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_RS04825	COG1902	pentaerythritol trinitrate reductase activity
AOR13_RS04850	COG0789	Transcriptional regulator
AOR13_RS04890	COG2826	transposase and inactivated derivatives, IS30 family
AOR13_RS04915	COG1073	alpha beta
AOR13_RS04920	COG2207	Transcriptional regulator
AOR13_RS04955	COG3101	peptidyl-lysine hydroxylation
AOR13_RS04985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOR13_RS04985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOR13_RS05010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_RS05025	COG0101	tRNA pseudouridine synthase activity
AOR13_RS05035	COG0285	dihydrofolate synthase activity
AOR13_RS05040	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AOR13_RS05045	COG1286	toxin biosynthetic process
AOR13_RS05050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOR13_RS05065	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AOR13_RS05075	COG0604	alcohol dehydrogenase
AOR13_RS05085	COG2080	2 iron, 2 sulfur cluster binding
AOR13_RS05090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOR13_RS05095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOR13_RS05100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOR13_RS05120	COG2268	Band 7 protein
AOR13_RS05135	COG1785	Belongs to the alkaline phosphatase family
AOR13_RS05140	COG1785	Belongs to the alkaline phosphatase family
AOR13_RS05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_RS05170	COG0741	lytic transglycosylase activity
AOR13_RS05170	COG1388	LysM domain
AOR13_RS05175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_RS05180	COG2226	methyltransferase
AOR13_RS05185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS05185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS05190	COG0489	protein tyrosine kinase activity
AOR13_RS05200	COG0471	metal ion transport
AOR13_RS05220	COG0778	Nitroreductase
AOR13_RS05240	COG0330	HflC and HflK could
AOR13_RS05250	COG0753	catalase activity
AOR13_RS05260	COG0840	transmembrane signaling receptor activity
AOR13_RS05285	COG0738	Major facilitator superfamily
AOR13_RS05320	COG3850	Histidine kinase
AOR13_RS05320	COG5002	protein histidine kinase activity
AOR13_RS05325	COG0745	RESPONSE REGULATOR receiver
AOR13_RS05350	COG1764	response to oxidative stress
AOR13_RS05355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOR13_RS05365	COG0746	molybdenum cofactor guanylyltransferase activity
AOR13_RS05380	COG3300	MHYT domain
AOR13_RS05380	COG5001	Diguanylate cyclase
AOR13_RS05395	COG0673	inositol 2-dehydrogenase activity
AOR13_RS05400	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_RS05405	COG1609	Transcriptional regulator
AOR13_RS05425	COG1024	Enoyl-CoA hydratase
AOR13_RS05435	COG2356	endonuclease I
AOR13_RS05455	COG4677	pectinesterase activity
AOR13_RS05465	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AOR13_RS05475	COG2755	lipolytic protein G-D-S-L family
AOR13_RS05480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_RS05485	COG0246	Mannitol dehydrogenase
AOR13_RS05490	COG1904	glucuronate isomerase
AOR13_RS05495	COG2721	sulfolactate sulfo-lyase activity
AOR13_RS05520	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AOR13_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS05535	COG3665	Urea carboxylase-associated protein
AOR13_RS05560	COG0745	RESPONSE REGULATOR receiver
AOR13_RS05565	COG2205	protein histidine kinase activity
AOR13_RS05610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOR13_RS05615	COG0469	pyruvate kinase activity
AOR13_RS05620	COG1737	Transcriptional regulator
AOR13_RS05625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOR13_RS05635	COG0129	dihydroxy-acid dehydratase activity
AOR13_RS05645	COG0800	Aldolase
AOR13_RS05650	COG0676	glucose-6-phosphate 1-epimerase activity
AOR13_RS05660	COG1640	4-alpha-glucanotransferase
AOR13_RS05665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOR13_RS05675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOR13_RS05695	COG2866	Carboxypeptidase
AOR13_RS05700	COG1115	amino acid carrier protein
AOR13_RS05710	COG3139	Protein of unknown function (DUF1315)
AOR13_RS05735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOR13_RS05760	COG2205	protein histidine kinase activity
AOR13_RS05760	COG0784	Response regulator, receiver
AOR13_RS05765	COG0784	Response regulator, receiver
AOR13_RS05770	COG4251	negative regulation of phosphorylation
AOR13_RS05780	COG2204	response regulator
AOR13_RS05790	COG0583	DNA-binding transcription factor activity
AOR13_RS05800	COG0640	Transcriptional regulator
AOR13_RS05820	COG0583	DNA-binding transcription factor activity
AOR13_RS05835	COG3132	Protein of unknown function, DUF480
AOR13_RS05845	COG3300	MHYT domain
AOR13_RS05845	COG5001	Diguanylate cyclase
AOR13_RS05850	COG1022	Amp-dependent synthetase and ligase
AOR13_RS05860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOR13_RS05865	COG1074	ATP-dependent DNA helicase activity
AOR13_RS05870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOR13_RS05885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOR13_RS05900	COG3268	Saccharopine dehydrogenase
AOR13_RS05905	COG0436	Aminotransferase
AOR13_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS06135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOR13_RS06140	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOR13_RS06145	COG0315	cyclic pyranopterin monophosphate synthase activity
AOR13_RS06150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AOR13_RS06155	COG0314	molybdopterin synthase activity
AOR13_RS06170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOR13_RS06175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOR13_RS06195	COG4771	TonB-dependent receptor
AOR13_RS06205	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS06235	COG0596	Alpha beta hydrolase
AOR13_RS06240	COG1024	Enoyl-CoA hydratase
AOR13_RS06240	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_RS06245	COG0183	Belongs to the thiolase family
AOR13_RS06250	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS06255	COG0596	Alpha beta hydrolase
AOR13_RS06270	COG2390	Transcriptional regulator
AOR13_RS06275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_RS06285	COG0246	Mannitol dehydrogenase
AOR13_RS06305	COG0668	transmembrane transport
AOR13_RS06325	COG0668	transmembrane transport
AOR13_RS06330	COG4771	TonB-dependent receptor
AOR13_RS06350	COG2205	protein histidine kinase activity
AOR13_RS06350	COG2198	Histidine kinase
AOR13_RS06350	COG0784	Response regulator, receiver
AOR13_RS06355	COG3437	response regulator, receiver
AOR13_RS06365	COG0195	Participates in both transcription termination and antitermination
AOR13_RS06380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOR13_RS06390	COG4269	membrane
AOR13_RS06400	COG3706	GGDEF domain
AOR13_RS06405	COG0596	Alpha beta hydrolase
AOR13_RS06415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_RS06415	COG3153	acetyltransferase
AOR13_RS06450	COG4774	siderophore transport
AOR13_RS06475	COG1032	radical SAM domain protein
AOR13_RS06490	COG4771	TonB-dependent receptor
AOR13_RS06505	COG4134	Bacterial extracellular solute-binding protein
AOR13_RS06510	COG4135	transport system, permease component
AOR13_RS06515	COG4136	ATPase activity
AOR13_RS06520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOR13_RS06535	COG5001	Diguanylate cyclase
AOR13_RS06535	COG4251	negative regulation of phosphorylation
AOR13_RS06535	COG3706	GGDEF domain
AOR13_RS06535	COG2203	Gaf domain
AOR13_RS06550	COG3300	MHYT domain
AOR13_RS06550	COG5001	Diguanylate cyclase
AOR13_RS06570	COG0583	DNA-binding transcription factor activity
AOR13_RS06600	COG1595	DNA-templated transcription, initiation
AOR13_RS06610	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS06640	COG2814	Major facilitator Superfamily
AOR13_RS06645	COG4771	TonB-dependent receptor
AOR13_RS06665	COG2867	negative regulation of translational initiation
AOR13_RS06670	COG2914	Belongs to the UPF0125 (RnfH) family
AOR13_RS06680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOR13_RS06690	COG0457	Tetratricopeptide repeat
AOR13_RS06695	COG2318	DinB family
AOR13_RS06715	COG0477	Major facilitator Superfamily
AOR13_RS06740	COG0295	cytidine deaminase activity
AOR13_RS06760	COG1196	nuclear chromosome segregation
AOR13_RS06770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOR13_RS06785	COG1132	(ABC) transporter
AOR13_RS06790	COG1663	tetraacyldisaccharide 4'-kinase activity
AOR13_RS06830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOR13_RS06835	COG0579	oxidoreductase
AOR13_RS06840	COG0435	Glutathione S-transferase
AOR13_RS06865	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOR13_RS06870	COG1053	succinate dehydrogenase
AOR13_RS06880	COG0567	Dehydrogenase, E1 component
AOR13_RS06885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_RS06920	COG4667	esterase of the alpha-beta hydrolase superfamily
AOR13_RS06940	COG0366	Alpha amylase catalytic
AOR13_RS06955	COG1609	Transcriptional regulator
AOR13_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS06970	COG2267	carboxylic ester hydrolase activity
AOR13_RS06980	COG0616	signal peptide processing
AOR13_RS07005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOR13_RS07010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOR13_RS07015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOR13_RS07020	COG0386	Belongs to the glutathione peroxidase family
AOR13_RS07025	COG2084	Dehydrogenase
AOR13_RS07035	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS07040	COG1024	Enoyl-CoA hydratase
AOR13_RS07045	COG2226	methyltransferase
AOR13_RS07055	COG3083	sulfuric ester hydrolase activity
AOR13_RS07060	COG3082	Protein of unknown function (DUF1414)
AOR13_RS07065	COG3081	Nucleoid-associated protein
AOR13_RS07095	COG3275	phosphorelay sensor kinase activity
AOR13_RS07100	COG3279	Response regulator of the LytR AlgR family
AOR13_RS07105	COG0205	6-phosphofructokinase activity
AOR13_RS07115	COG2205	protein histidine kinase activity
AOR13_RS07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_RS07215	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_RS07220	COG2801	Transposase and inactivated derivatives
AOR13_RS07225	COG0513	Belongs to the DEAD box helicase family
AOR13_RS07230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOR13_RS07235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOR13_RS07240	COG0583	DNA-binding transcription factor activity
AOR13_RS07260	COG1760	l-serine dehydratase
AOR13_RS07265	COG0494	nUDIX hydrolase
AOR13_RS07270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOR13_RS07285	COG1404	Belongs to the peptidase S8 family
AOR13_RS07290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOR13_RS07295	COG0022	dehydrogenase e1 component
AOR13_RS07300	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_RS07305	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOR13_RS07310	COG0515	serine threonine protein kinase
AOR13_RS07315	COG1946	Acyl-CoA thioesterase
AOR13_RS07325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOR13_RS07335	COG1956	GAF domain-containing protein
AOR13_RS07350	COG0793	Belongs to the peptidase S41A family
AOR13_RS07355	COG0733	neurotransmitter:sodium symporter activity
AOR13_RS07360	COG1757	Na H antiporter
AOR13_RS07365	COG0308	aminopeptidase N
AOR13_RS07395	COG2902	Dehydrogenase
AOR13_RS07400	COG0167	dihydroorotate dehydrogenase activity
AOR13_RS07415	COG0488	(ABC) transporter
AOR13_RS07425	COG3130	regulation of translation
AOR13_RS07430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOR13_RS07440	COG0415	Belongs to the DNA photolyase family
AOR13_RS07445	COG0415	Belongs to the DNA photolyase family
AOR13_RS07450	COG3046	protein related to deoxyribodipyrimidine photolyase
AOR13_RS07475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOR13_RS07480	COG0589	response to stress
AOR13_RS07490	COG0069	glutamate synthase activity
AOR13_RS07505	COG2193	ferroxidase activity
AOR13_RS07515	COG3278	Belongs to the heme-copper respiratory oxidase family
AOR13_RS07530	COG2010	Cytochrome c
AOR13_RS07555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOR13_RS07565	COG0037	tRNA processing
AOR13_RS07570	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOR13_RS07590	COG1280	lysine exporter protein (LysE YggA)
AOR13_RS07600	COG2897	thiosulfate sulfurtransferase activity
AOR13_RS07605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AOR13_RS07610	COG3148	PFAM DTW domain containing protein
AOR13_RS07680	COG0582	viral genome integration into host DNA
AOR13_RS07705	COG0322	excinuclease ABC activity
AOR13_RS07710	COG2197	response regulator
AOR13_RS07715	COG1741	Belongs to the pirin family
AOR13_RS07725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOR13_RS07755	COG0642	Histidine kinase
AOR13_RS07760	COG0745	RESPONSE REGULATOR receiver
AOR13_RS07785	COG0670	Belongs to the BI1 family
AOR13_RS07795	COG2923	Belongs to the DsrF TusC family
AOR13_RS07805	COG2920	part of a sulfur-relay system
AOR13_RS07810	COG0561	phosphatase activity
AOR13_RS07825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOR13_RS07830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOR13_RS07835	COG1674	ftsk spoiiie
AOR13_RS07835	COG0531	amino acid
AOR13_RS07845	COG0686	Belongs to the AlaDH PNT family
AOR13_RS07850	COG0284	orotidine-5'-phosphate decarboxylase activity
AOR13_RS07855	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AOR13_RS07860	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AOR13_RS07870	COG0776	regulation of translation
AOR13_RS07875	COG0539	negative regulation of cytoplasmic translation
AOR13_RS07880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOR13_RS07885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOR13_RS07890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AOR13_RS07905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOR13_RS07910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOR13_RS07915	COG0633	Ferredoxin
AOR13_RS07920	COG5002	protein histidine kinase activity
AOR13_RS07995	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_RS08025	COG1131	(ABC) transporter
AOR13_RS08060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AOR13_RS08065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOR13_RS08075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOR13_RS08085	COG4783	chaperone-mediated protein folding
AOR13_RS08095	COG1393	Belongs to the ArsC family
AOR13_RS08130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOR13_RS08165	COG0572	uridine kinase
AOR13_RS08170	COG3769	mannosylglycerate metabolic process
AOR13_RS08175	COG1215	transferase activity, transferring glycosyl groups
AOR13_RS08185	COG0303	'Molybdopterin
AOR13_RS08190	COG0534	Mate efflux family protein
AOR13_RS08205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOR13_RS08210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOR13_RS08220	COG0405	Gamma-glutamyltransferase
AOR13_RS08225	COG1024	Enoyl-CoA hydratase
AOR13_RS08260	COG1448	Aminotransferase
AOR13_RS08265	COG1671	Belongs to the UPF0178 family
AOR13_RS08270	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS08280	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS08285	COG1917	Cupin 2, conserved barrel domain protein
AOR13_RS08285	COG2207	Transcriptional regulator
AOR13_RS08335	COG0596	Alpha beta hydrolase
AOR13_RS08345	COG0716	FMN binding
AOR13_RS08365	COG3265	gluconokinase activity
AOR13_RS08370	COG1609	Transcriptional regulator
AOR13_RS08380	COG1984	allophanate hydrolase subunit 2
AOR13_RS08390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOR13_RS08395	COG2996	Protein conserved in bacteria
AOR13_RS08400	COG1765	OsmC-like protein
AOR13_RS08405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS08430	COG0436	Aminotransferase
AOR13_RS08435	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOR13_RS08440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOR13_RS08450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOR13_RS08460	COG1238	metal cluster binding
AOR13_RS08505	COG4628	conserved protein (DUF2132)
AOR13_RS08515	COG0454	-acetyltransferase
AOR13_RS08520	COG1119	ATPase activity
AOR13_RS08530	COG1185	polyribonucleotide nucleotidyltransferase activity
AOR13_RS08545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOR13_RS08550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOR13_RS08555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_RS08595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOR13_RS08600	COG0149	triose-phosphate isomerase activity
AOR13_RS08605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOR13_RS08610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOR13_RS08620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AOR13_RS08625	COG1534	Rna-binding protein
AOR13_RS08635	COG1067	ATP-dependent peptidase activity
AOR13_RS08640	COG0495	leucyl-tRNA aminoacylation
AOR13_RS08650	COG1466	dna polymerase III delta subunit
AOR13_RS08655	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOR13_RS08660	COG0799	negative regulation of ribosome biogenesis
AOR13_RS08665	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AOR13_RS08670	COG0768	penicillin binding
AOR13_RS08675	COG0772	Belongs to the SEDS family
AOR13_RS08680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOR13_RS08685	COG1686	Belongs to the peptidase S11 family
AOR13_RS08690	COG2921	Belongs to the UPF0250 family
AOR13_RS08695	COG0321	lipoyl(octanoyl) transferase activity
AOR13_RS08700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOR13_RS08710	COG0252	asparaginase activity
AOR13_RS08720	COG0778	Nitroreductase
AOR13_RS08735	COG0616	signal peptide processing
AOR13_RS08755	COG0492	ferredoxin-NADP+ reductase activity
AOR13_RS08760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOR13_RS08765	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AOR13_RS08770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOR13_RS08775	COG0542	response to heat
AOR13_RS08780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOR13_RS08785	COG1278	Cold shock
AOR13_RS08795	COG1187	pseudouridine synthase activity
AOR13_RS08800	COG0482	sulfurtransferase activity
AOR13_RS08805	COG2915	High frequency lysogenization protein hflD homolog
AOR13_RS08810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOR13_RS08820	COG2850	peptidyl-arginine hydroxylation
AOR13_RS08835	COG0277	FAD linked oxidase domain protein
AOR13_RS08835	COG0247	lactate metabolic process
AOR13_RS08840	COG3123	guanosine phosphorylase activity
AOR13_RS08845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOR13_RS08890	COG1695	Transcriptional regulator
AOR13_RS08905	COG1077	Cell shape determining protein MreB Mrl
AOR13_RS08930	COG3265	gluconokinase activity
AOR13_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS08955	COG1609	Transcriptional regulator
AOR13_RS08960	COG0679	Auxin Efflux Carrier
AOR13_RS08980	COG0574	Belongs to the PEP-utilizing enzyme family
AOR13_RS08980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOR13_RS09000	COG1942	4-Oxalocrotonate Tautomerase
AOR13_RS09020	COG1714	RDD family
AOR13_RS09045	COG0702	epimerase
AOR13_RS09055	COG0084	hydrolase, TatD family'
AOR13_RS09060	COG0470	DNA polymerase III
AOR13_RS09070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOR13_RS09075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOR13_RS09080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOR13_RS09085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOR13_RS09100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOR13_RS09105	COG0416	fatty acid biosynthetic process
AOR13_RS09115	COG1399	metal-binding, possibly nucleic acid-binding protein
AOR13_RS09120	COG0424	maF-like protein
AOR13_RS09125	COG0546	phosphoglycolate phosphatase activity
AOR13_RS09135	COG1530	ribonuclease E activity
AOR13_RS09155	COG2153	protein acetylation
AOR13_RS09175	COG0625	glutathione transferase activity
AOR13_RS09190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_RS09200	COG0583	DNA-binding transcription factor activity
AOR13_RS09210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOR13_RS09215	COG3724	N-succinylarginine dihydrolase activity
AOR13_RS09225	COG1301	dicarboxylic acid transport
AOR13_RS09230	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOR13_RS09240	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AOR13_RS09275	COG0328	RNA-DNA hybrid ribonuclease activity
AOR13_RS09280	COG3321	synthase
AOR13_RS09280	COG0604	alcohol dehydrogenase
AOR13_RS09300	COG1643	Atp-dependent helicase
AOR13_RS09340	COG3437	response regulator, receiver
AOR13_RS09340	COG3850	Histidine kinase
AOR13_RS09340	COG2205	protein histidine kinase activity
AOR13_RS09340	COG4999	Histidine kinase
AOR13_RS09345	COG2925	Exonuclease
AOR13_RS09360	COG0183	Belongs to the thiolase family
AOR13_RS09365	COG0789	Transcriptional regulator
AOR13_RS09370	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS09375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOR13_RS09380	COG1024	Enoyl-CoA hydratase
AOR13_RS09385	COG4770	biotin carboxylase activity
AOR13_RS09415	COG1957	nucleoside hydrolase
AOR13_RS09430	COG2814	Major facilitator Superfamily
AOR13_RS09465	COG0708	Exodeoxyribonuclease III
AOR13_RS09485	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOR13_RS09495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOR13_RS09505	COG2096	Adenosyltransferase
AOR13_RS09510	COG0471	metal ion transport
AOR13_RS09515	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_RS09525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOR13_RS09540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS09540	COG0072	phenylalanine-tRNA ligase activity
AOR13_RS09580	COG2244	polysaccharide biosynthetic process
AOR13_RS09590	COG1215	transferase activity, transferring glycosyl groups
AOR13_RS09605	COG0438	transferase activity, transferring glycosyl groups
AOR13_RS09640	COG4464	protein tyrosine phosphatase activity
AOR13_RS09645	COG0489	protein tyrosine kinase activity
AOR13_RS09650	COG1596	polysaccharide export
AOR13_RS09660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOR13_RS09680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOR13_RS09695	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS09735	COG0730	response to heat
AOR13_RS09740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOR13_RS09755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_RS09760	COG2233	PERMEase
AOR13_RS09775	COG0784	Response regulator, receiver
AOR13_RS09775	COG5002	protein histidine kinase activity
AOR13_RS09785	COG3300	MHYT domain
AOR13_RS09785	COG5001	Diguanylate cyclase
AOR13_RS09795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_RS09800	COG2252	PERMEase
AOR13_RS09815	COG1309	transcriptional regulator
AOR13_RS09825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOR13_RS09840	COG2351	hydroxyisourate hydrolase activity
AOR13_RS09845	COG0402	S-adenosylhomocysteine deaminase activity
AOR13_RS09855	COG5002	protein histidine kinase activity
AOR13_RS09855	COG5001	Diguanylate cyclase
AOR13_RS09855	COG3447	MASE1 domain protein
AOR13_RS09875	COG3706	GGDEF domain
AOR13_RS09890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AOR13_RS09910	COG2190	(PTS) system
AOR13_RS09910	COG2211	Major facilitator Superfamily
AOR13_RS09915	COG1393	Belongs to the ArsC family
AOR13_RS09945	COG2988	succinylglutamate desuccinylase activity
AOR13_RS09955	COG0058	SHG alpha-glucan phosphorylase activity
AOR13_RS09960	COG0033	Phosphoglucomutase
AOR13_RS09965	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AOR13_RS09970	COG0714	Associated with various cellular activities
AOR13_RS09985	COG2116	formate transmembrane transporter activity
AOR13_RS09990	COG0515	serine threonine protein kinase
AOR13_RS09990	COG2815	serine threonine protein kinase
AOR13_RS09995	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOR13_RS10000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOR13_RS10020	COG0583	DNA-binding transcription factor activity
AOR13_RS10030	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AOR13_RS10040	COG3437	response regulator, receiver
AOR13_RS10040	COG0784	Response regulator, receiver
AOR13_RS10045	COG2890	protein-(glutamine-N5) methyltransferase activity
AOR13_RS10055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOR13_RS10060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOR13_RS10065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOR13_RS10075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOR13_RS10080	COG5001	Diguanylate cyclase
AOR13_RS10090	COG1064	alcohol dehydrogenase
AOR13_RS10105	COG0012	GTP binding
AOR13_RS10110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_RS10135	COG1115	amino acid carrier protein
AOR13_RS10140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOR13_RS10155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_RS10165	COG1702	phosphate starvation-inducible protein PhoH
AOR13_RS10175	COG4535	Mg2 and Co2 transporter CorC
AOR13_RS10180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AOR13_RS10185	COG0857	belongs to the CobB CobQ family
AOR13_RS10185	COG0280	phosphate acetyltransferase
AOR13_RS10195	COG0071	Belongs to the small heat shock protein (HSP20) family
AOR13_RS10225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOR13_RS10230	COG0505	Belongs to the CarA family
AOR13_RS10235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOR13_RS10250	COG4251	negative regulation of phosphorylation
AOR13_RS10250	COG3706	GGDEF domain
AOR13_RS10250	COG2203	Gaf domain
AOR13_RS10250	COG5001	Diguanylate cyclase
AOR13_RS10255	COG3909	cytochrome
AOR13_RS10260	COG0484	heat shock protein binding
AOR13_RS10270	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOR13_RS10275	COG0784	Response regulator, receiver
AOR13_RS10275	COG2205	protein histidine kinase activity
AOR13_RS10285	COG4771	TonB-dependent receptor
AOR13_RS10290	COG2610	gluconate transmembrane transporter activity
AOR13_RS10295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOR13_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS10310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOR13_RS10315	COG0497	DNA recombination
AOR13_RS10320	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_RS10325	COG0500	methyltransferase
AOR13_RS10330	COG2733	membrane
AOR13_RS10345	COG0110	maltose O-acetyltransferase activity
AOR13_RS10350	COG0656	L-ascorbic acid biosynthetic process
AOR13_RS10365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOR13_RS10370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOR13_RS10375	COG0009	L-threonylcarbamoyladenylate synthase
AOR13_RS10380	COG0613	PHP domain protein
AOR13_RS10385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOR13_RS10395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOR13_RS10400	COG0134	indole-3-glycerol-phosphate synthase activity
AOR13_RS10400	COG0135	phosphoribosylanthranilate isomerase activity
AOR13_RS10410	COG0159	tryptophan synthase activity
AOR13_RS10415	COG2350	Protein conserved in bacteria
AOR13_RS10435	COG2205	protein histidine kinase activity
AOR13_RS10440	COG0628	permease
AOR13_RS10445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOR13_RS10450	COG1090	epimerase
AOR13_RS10455	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOR13_RS10460	COG4181	ATPase activity
AOR13_RS10480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_RS10520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOR13_RS10540	COG0745	RESPONSE REGULATOR receiver
AOR13_RS10550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOR13_RS10555	COG5265	(ABC) transporter
AOR13_RS10570	COG5433	transposase activity
AOR13_RS10575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOR13_RS10585	COG4139	cobalamin transport
AOR13_RS10590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOR13_RS10605	COG2226	methyltransferase
AOR13_RS10605	COG1073	alpha beta
AOR13_RS10610	COG0156	8-amino-7-oxononanoate synthase activity
AOR13_RS10635	COG0456	acetyltransferase
AOR13_RS10640	COG0189	ligase activity
AOR13_RS10655	COG0017	Asparaginyl-tRNA synthetase
AOR13_RS10665	COG2995	paraquat-inducible protein a
AOR13_RS10670	COG3008	intermembrane lipid transfer
AOR13_RS10670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOR13_RS10700	COG0583	DNA-binding transcription factor activity
AOR13_RS10705	COG1309	transcriptional regulator
AOR13_RS10715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_RS10720	COG0517	IMP dehydrogenase activity
AOR13_RS10735	COG0583	DNA-binding transcription factor activity
AOR13_RS10740	COG3038	cytochrome b561
AOR13_RS10775	COG2271	Major facilitator Superfamily
AOR13_RS10780	COG0784	Response regulator, receiver
AOR13_RS10780	COG2205	protein histidine kinase activity
AOR13_RS10855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOR13_RS10875	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AOR13_RS10880	COG2885	chlorophyll binding
AOR13_RS10885	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_RS10900	COG0811	peptide transport
AOR13_RS10905	COG0824	Thioesterase
AOR13_RS10910	COG2255	four-way junction helicase activity
AOR13_RS10915	COG0632	four-way junction helicase activity
AOR13_RS10920	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOR13_RS10925	COG0494	nUDIX hydrolase
AOR13_RS10930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOR13_RS10945	COG2204	response regulator
AOR13_RS10955	COG2205	protein histidine kinase activity
AOR13_RS10985	COG0023	Translation Initiation Factor
AOR13_RS10990	COG0745	RESPONSE REGULATOR receiver
AOR13_RS10995	COG1605	Chorismate mutase
AOR13_RS10995	COG0077	Prephenate dehydratase
AOR13_RS11000	COG0840	transmembrane signaling receptor activity
AOR13_RS11005	COG1605	Chorismate mutase
AOR13_RS11005	COG0287	Prephenate dehydrogenase
AOR13_RS11010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOR13_RS11015	COG2860	membrane
AOR13_RS11030	COG0335	large ribosomal subunit rRNA binding
AOR13_RS11035	COG0336	Belongs to the RNA methyltransferase TrmD family
AOR13_RS11040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOR13_RS11045	COG0228	four-way junction DNA binding
AOR13_RS11060	COG2873	o-acetylhomoserine
AOR13_RS11065	COG1132	(ABC) transporter
AOR13_RS11070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS11080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOR13_RS11110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOR13_RS11115	COG4137	Cytochrome C assembly protein
AOR13_RS11120	COG4536	flavin adenine dinucleotide binding
AOR13_RS11130	COG2062	phosphohistidine phosphatase, SixA
AOR13_RS11135	COG1025	Belongs to the peptidase M16 family
AOR13_RS11150	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_RS11150	COG1024	Enoyl-CoA hydratase
AOR13_RS11160	COG0714	Associated with various cellular activities
AOR13_RS11180	COG2304	oxidoreductase activity
AOR13_RS11205	COG3706	GGDEF domain
AOR13_RS11210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_RS11215	COG0175	sulfate reduction
AOR13_RS11220	COG0529	Catalyzes the synthesis of activated sulfate
AOR13_RS11235	COG3273	potassium ion transport
AOR13_RS11235	COG0471	metal ion transport
AOR13_RS11260	COG0367	asparagine synthase
AOR13_RS11270	COG0602	queuosine metabolic process
AOR13_RS11295	COG0556	nucleotide-excision repair
AOR13_RS11300	COG0534	Mate efflux family protein
AOR13_RS11315	COG4657	Part of a membrane complex involved in electron transport
AOR13_RS11320	COG2878	Part of a membrane complex involved in electron transport
AOR13_RS11325	COG4656	Part of a membrane complex involved in electron transport
AOR13_RS11330	COG4658	electron transport chain
AOR13_RS11335	COG4659	FMN binding
AOR13_RS11340	COG4660	Part of a membrane complex involved in electron transport
AOR13_RS11345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOR13_RS11365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOR13_RS11370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOR13_RS11375	COG4946	Tricorn protease homolog
AOR13_RS11375	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_RS11375	COG1506	peptidase
AOR13_RS11400	COG1278	Cold shock
AOR13_RS11405	COG0346	lactoylglutathione lyase activity
AOR13_RS11410	COG0584	glycerophosphoryl diester phosphodiesterase
AOR13_RS11415	COG2885	chlorophyll binding
AOR13_RS11420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOR13_RS11425	COG0450	alkyl hydroperoxide reductase
AOR13_RS11450	COG4771	TonB-dependent receptor
AOR13_RS11455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOR13_RS11460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOR13_RS11465	COG2766	serine protein kinase
AOR13_RS11470	COG2718	Belongs to the UPF0229 family
AOR13_RS11475	COG2719	SpoVR family
AOR13_RS11495	COG2890	protein-(glutamine-N5) methyltransferase activity
AOR13_RS11500	COG2840	Smr protein MutS2
AOR13_RS11525	COG1136	(ABC) transporter
AOR13_RS11545	COG2918	glutathione biosynthetic process
AOR13_RS11550	COG0612	Peptidase, M16
AOR13_RS11560	COG0564	pseudouridine synthase activity
AOR13_RS11565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOR13_RS11570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOR13_RS11595	COG2175	clavaminate synthase activity
AOR13_RS11625	COG0583	DNA-binding transcription factor activity
AOR13_RS11640	COG0456	acetyltransferase
AOR13_RS11695	COG0848	biopolymer transport protein
AOR13_RS11700	COG0811	peptide transport
AOR13_RS11705	COG0811	peptide transport
AOR13_RS11745	COG0457	Tetratricopeptide repeat
AOR13_RS11770	COG1522	sequence-specific DNA binding
AOR13_RS11775	COG0625	glutathione transferase activity
AOR13_RS11805	COG1842	Phage shock protein A
AOR13_RS11810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AOR13_RS11815	COG0747	negative chemotaxis
AOR13_RS11820	COG4168	peptide transport system, permease
AOR13_RS11825	COG4171	peptide transport system, permease
AOR13_RS11830	COG4172	Belongs to the ABC transporter superfamily
AOR13_RS11835	COG4172	Belongs to the ABC transporter superfamily
AOR13_RS11840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AOR13_RS11855	COG1607	acyl-coa hydrolase
AOR13_RS11880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOR13_RS11895	COG3590	peptidase
AOR13_RS11900	COG1309	transcriptional regulator
AOR13_RS11910	COG0659	secondary active sulfate transmembrane transporter activity
AOR13_RS11915	COG0288	reversible hydration of carbon dioxide
AOR13_RS11920	COG0583	DNA-binding transcription factor activity
AOR13_RS11925	COG0583	DNA-binding transcription factor activity
AOR13_RS11935	COG0646	methionine synthase
AOR13_RS11935	COG1410	methionine synthase
AOR13_RS11940	COG1410	methionine synthase
AOR13_RS11940	COG0646	methionine synthase
AOR13_RS11955	COG0835	chemotaxis
AOR13_RS11965	COG1192	Involved in chromosome partitioning
AOR13_RS11970	COG2201	protein-glutamate methylesterase activity
AOR13_RS11975	COG0643	Histidine kinase
AOR13_RS11975	COG2198	Histidine kinase
AOR13_RS11975	COG0784	Response regulator, receiver
AOR13_RS11980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AOR13_RS12005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOR13_RS12020	COG1987	bacterial-type flagellum assembly
AOR13_RS12070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOR13_RS12075	COG1766	The M ring may be actively involved in energy transduction
AOR13_RS12105	COG1086	Polysaccharide biosynthesis protein
AOR13_RS12110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOR13_RS12115	COG1083	cytidylyl-transferase
AOR13_RS12125	COG2089	acid synthase
AOR13_RS12140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_RS12180	COG2089	acid synthase
AOR13_RS12185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOR13_RS12190	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AOR13_RS12230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOR13_RS12235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOR13_RS12255	COG1256	bacterial-type flagellum assembly
AOR13_RS12260	COG3951	Flagellar rod assembly protein muramidase FlgJ
AOR13_RS12260	COG1705	Flagellar rod assembly protein muramidase FlgJ
AOR13_RS12280	COG4787	bacterial-type flagellum-dependent cell motility
AOR13_RS12285	COG1749	Flagellar hook protein flgE
AOR13_RS12300	COG1815	bacterial-type flagellum-dependent cell motility
AOR13_RS12305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOR13_RS12310	COG0784	Response regulator, receiver
AOR13_RS12310	COG0835	chemotaxis
AOR13_RS12350	COG2197	response regulator
AOR13_RS12355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS12365	COG2885	chlorophyll binding
AOR13_RS12385	COG2840	Smr protein MutS2
AOR13_RS12390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOR13_RS12390	COG0047	phosphoribosylformylglycinamidine synthase activity
AOR13_RS12420	COG0037	tRNA processing
AOR13_RS12425	COG0825	malonyl-CoA metabolic process
AOR13_RS12430	COG0587	DNA-directed DNA polymerase activity
AOR13_RS12445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOR13_RS12450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOR13_RS12465	COG0750	zinc metalloprotease
AOR13_RS12470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOR13_RS12475	COG0575	Belongs to the CDS family
AOR13_RS12480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOR13_RS12490	COG0528	UMP kinase activity
AOR13_RS12500	COG0052	Belongs to the universal ribosomal protein uS2 family
AOR13_RS12505	COG0024	Methionine aminopeptidase
AOR13_RS12510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOR13_RS12525	COG0564	pseudouridine synthase activity
AOR13_RS12595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOR13_RS12595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOR13_RS12605	COG1611	Belongs to the LOG family
AOR13_RS12620	COG0473	3-isopropylmalate dehydrogenase activity
AOR13_RS12625	COG1596	polysaccharide export
AOR13_RS12625	COG1555	photosystem II stabilization
AOR13_RS12630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOR13_RS12660	COG1682	transport, permease protein
AOR13_RS12685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOR13_RS12690	COG2853	Lipoprotein
AOR13_RS12705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOR13_RS12710	COG1138	Cytochrome C-type biogenesis protein
AOR13_RS12720	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_RS12725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_RS12730	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_RS12735	COG4133	protoheme IX ABC transporter activity
AOR13_RS12755	COG1668	transmembrane transport
AOR13_RS12760	COG4555	ABC transporter
AOR13_RS12775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOR13_RS12805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOR13_RS12810	COG0473	3-isopropylmalate dehydrogenase activity
AOR13_RS12820	COG0066	3-isopropylmalate dehydratase activity
AOR13_RS12825	COG3437	response regulator, receiver
AOR13_RS12825	COG0784	Response regulator, receiver
AOR13_RS12835	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_RS12835	COG3267	Type II secretory pathway component ExeA
AOR13_RS12845	COG0513	Belongs to the DEAD box helicase family
AOR13_RS12855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOR13_RS12885	COG1346	cytolysis
AOR13_RS12985	COG4667	esterase of the alpha-beta hydrolase superfamily
AOR13_RS13020	COG0488	(ABC) transporter
AOR13_RS13025	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOR13_RS13030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOR13_RS13035	COG2971	BadF BadG BcrA BcrD
AOR13_RS13045	COG3706	GGDEF domain
AOR13_RS13050	COG0419	ATPase involved in DNA repair
AOR13_RS13055	COG0420	3'-5' exonuclease activity
AOR13_RS13065	COG1739	Uncharacterized protein family UPF0029
AOR13_RS13080	COG1764	response to oxidative stress
AOR13_RS13085	COG1846	Transcriptional regulator
AOR13_RS13090	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_RS13105	COG2207	Transcriptional regulator
AOR13_RS13110	COG3291	Pkd domain containing protein
AOR13_RS13110	COG4447	cellulose binding
AOR13_RS13110	COG5520	Belongs to the glycosyl hydrolase 30 family
AOR13_RS13115	COG2115	Belongs to the xylose isomerase family
AOR13_RS13120	COG1070	Carbohydrate kinase
AOR13_RS13125	COG2207	Transcriptional regulator
AOR13_RS13125	COG1609	Transcriptional regulator
AOR13_RS13130	COG0477	Major facilitator Superfamily
AOR13_RS13150	COG1272	protein, Hemolysin III
AOR13_RS13175	COG0583	DNA-binding transcription factor activity
AOR13_RS13185	COG0306	phosphate transporter
AOR13_RS13195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOR13_RS13205	COG0573	inorganic phosphate transmembrane transporter activity
AOR13_RS13215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOR13_RS13220	COG0248	Ppx GppA phosphatase
AOR13_RS13225	COG1506	peptidase
AOR13_RS13225	COG4946	Tricorn protease homolog
AOR13_RS13225	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_RS13230	COG3588	fructose-bisphosphate aldolase
AOR13_RS13235	COG0126	phosphoglycerate kinase activity
AOR13_RS13245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOR13_RS13270	COG1979	alcohol dehydrogenase
AOR13_RS13275	COG2207	Transcriptional regulator
AOR13_RS13285	COG0784	Response regulator, receiver
AOR13_RS13285	COG2205	protein histidine kinase activity
AOR13_RS13290	COG3300	MHYT domain
AOR13_RS13290	COG5001	Diguanylate cyclase
AOR13_RS13300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_RS13315	COG2207	Transcriptional regulator
AOR13_RS13330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOR13_RS13340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOR13_RS13345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOR13_RS13355	COG5007	Belongs to the BolA IbaG family
AOR13_RS13365	COG2854	intermembrane phospholipid transfer
AOR13_RS13370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOR13_RS13375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOR13_RS13380	COG1127	ABC transporter
AOR13_RS13395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOR13_RS13410	COG1137	ATPase activity
AOR13_RS13435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOR13_RS13440	COG2239	Acts as a magnesium transporter
AOR13_RS13450	COG2207	Transcriptional regulator
AOR13_RS13450	COG3708	Transcriptional regulator
AOR13_RS13455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS13455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_RS13460	COG2969	positive regulation of protein catabolic process
AOR13_RS13465	COG0625	glutathione transferase activity
AOR13_RS13470	COG2857	Cytochrome c1
AOR13_RS13475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOR13_RS13480	COG0723	plastoquinol--plastocyanin reductase activity
AOR13_RS13485	COG1473	amidohydrolase
AOR13_RS13495	COG4206	TonB-dependent receptor
AOR13_RS13505	COG1595	DNA-templated transcription, initiation
AOR13_RS13510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOR13_RS13530	COG3956	TIGRFAM MazG family protein
AOR13_RS13535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOR13_RS13540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOR13_RS13550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOR13_RS13570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOR13_RS13580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AOR13_RS13585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AOR13_RS13590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_RS13595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOR13_RS13600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOR13_RS13610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOR13_RS13615	COG0840	transmembrane signaling receptor activity
AOR13_RS13620	COG0527	aspartate kinase activity
AOR13_RS13640	COG1049	propionate catabolic process, 2-methylcitrate cycle
AOR13_RS13645	COG2133	pyrroloquinoline quinone binding
AOR13_RS13665	COG3437	response regulator, receiver
AOR13_RS13670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOR13_RS13680	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AOR13_RS13685	COG0848	biopolymer transport protein
AOR13_RS13690	COG0811	peptide transport
AOR13_RS13695	COG0811	peptide transport
AOR13_RS13725	COG5002	protein histidine kinase activity
AOR13_RS13730	COG0745	RESPONSE REGULATOR receiver
AOR13_RS13735	COG4191	Histidine kinase
AOR13_RS13735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_RS13740	COG2974	May be involved in recombination
AOR13_RS13745	COG1396	sequence-specific DNA binding
AOR13_RS13750	COG3135	benzoate transporter
AOR13_RS13765	COG0537	adenosine 5'-monophosphoramidase activity
AOR13_RS13780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOR13_RS13785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOR13_RS13805	COG1610	YqeY-like protein
AOR13_RS13810	COG0358	DNA primase activity
AOR13_RS13835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_RS13840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS13855	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS13880	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS13895	COG0348	domain, Protein
AOR13_RS13900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOR13_RS13905	COG4206	TonB-dependent receptor
AOR13_RS13910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOR13_RS13925	COG1116	anion transmembrane transporter activity
AOR13_RS13930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOR13_RS13935	COG1116	anion transmembrane transporter activity
AOR13_RS13935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOR13_RS13950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOR13_RS13950	COG1648	precorrin-2 dehydrogenase activity
AOR13_RS13955	COG0243	molybdopterin cofactor binding
AOR13_RS13960	COG2146	nitrite reductase [NAD(P)H] activity
AOR13_RS13965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOR13_RS13970	COG0659	secondary active sulfate transmembrane transporter activity
AOR13_RS13980	COG3707	response regulator
AOR13_RS13990	COG0671	phosphoesterase, PA-phosphatase related
AOR13_RS13995	COG0271	Belongs to the BolA IbaG family
AOR13_RS14010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_RS14035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOR13_RS14040	COG1509	lysine 2,3-aminomutase activity
AOR13_RS14060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_RS14065	COG4251	negative regulation of phosphorylation
AOR13_RS14080	COG3150	esterase
AOR13_RS14095	COG0494	nUDIX hydrolase
AOR13_RS14100	COG1538	Outer membrane efflux protein
AOR13_RS14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOR13_RS14120	COG1648	precorrin-2 dehydrogenase activity
AOR13_RS14130	COG3119	arylsulfatase activity
AOR13_RS14135	COG3119	arylsulfatase activity
AOR13_RS14170	COG3119	arylsulfatase activity
AOR13_RS14270	COG2124	cytochrome p450
AOR13_RS14285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_RS14290	COG2814	Major facilitator Superfamily
AOR13_RS14295	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_RS14300	COG1063	alcohol dehydrogenase
AOR13_RS14305	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS14315	COG3119	arylsulfatase activity
AOR13_RS14320	COG1802	Transcriptional regulator
AOR13_RS14330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOR13_RS14340	COG0564	pseudouridine synthase activity
AOR13_RS14360	COG0784	Response regulator, receiver
AOR13_RS14360	COG5002	protein histidine kinase activity
AOR13_RS14365	COG3706	GGDEF domain
AOR13_RS14370	COG2201	protein-glutamate methylesterase activity
AOR13_RS14375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOR13_RS14380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOR13_RS14385	COG0730	response to heat
AOR13_RS14390	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AOR13_RS14395	COG0494	nUDIX hydrolase
AOR13_RS14410	COG3025	triphosphatase activity
AOR13_RS14415	COG4991	sh3 domain protein
AOR13_RS14430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_RS14445	COG0506	proline dehydrogenase activity
AOR13_RS14445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOR13_RS14445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOR13_RS14450	COG0840	transmembrane signaling receptor activity
AOR13_RS14460	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOR13_RS14475	COG0585	pseudouridine synthase activity
AOR13_RS14480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOR13_RS14490	COG1238	metal cluster binding
AOR13_RS14550	COG0142	geranyltranstransferase activity
AOR13_RS14560	COG0006	proline dipeptidase activity
AOR13_RS14570	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_RS14570	COG1024	Enoyl-CoA hydratase
AOR13_RS14575	COG0183	Belongs to the thiolase family
AOR13_RS14670	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_RS14695	COG2161	toxin-antitoxin pair type II binding
AOR13_RS14700	COG4115	mRNA cleavage
AOR13_RS14765	COG0346	lactoylglutathione lyase activity
AOR13_RS14785	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOR13_RS14790	COG3876	Protein conserved in bacteria
AOR13_RS14810	COG1757	Na H antiporter
AOR13_RS14830	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS14840	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AOR13_RS14850	COG3118	belongs to the thioredoxin family
AOR13_RS14860	COG2133	pyrroloquinoline quinone binding
AOR13_RS14865	COG0783	Belongs to the Dps family
AOR13_RS14880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOR13_RS14885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOR13_RS14890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOR13_RS14895	COG0784	Response regulator, receiver
AOR13_RS14895	COG2205	protein histidine kinase activity
AOR13_RS14900	COG1473	amidohydrolase
AOR13_RS14905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOR13_RS14910	COG3118	belongs to the thioredoxin family
AOR13_RS14915	COG0513	Belongs to the DEAD box helicase family
AOR13_RS14920	COG0248	Ppx GppA phosphatase
AOR13_RS14945	COG0805	protein transport
AOR13_RS14950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOR13_RS14970	COG0028	Belongs to the TPP enzyme family
AOR13_RS14985	COG0457	Tetratricopeptide repeat
AOR13_RS15005	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOR13_RS15010	COG1162	GTPase activity
AOR13_RS15025	COG0584	glycerophosphoryl diester phosphodiesterase
AOR13_RS15035	COG2861	carbohydrate metabolic process
AOR13_RS15045	COG4942	peptidase
AOR13_RS15055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_RS15070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOR13_RS15075	COG2267	carboxylic ester hydrolase activity
AOR13_RS15080	COG2205	protein histidine kinase activity
AOR13_RS15085	COG0745	RESPONSE REGULATOR receiver
AOR13_RS15100	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AOR13_RS15110	COG1803	Methylglyoxal synthase
AOR13_RS15125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOR13_RS15130	COG0137	argininosuccinate synthase activity
AOR13_RS15140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOR13_RS15140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOR13_RS15145	COG5001	Diguanylate cyclase
AOR13_RS15145	COG3300	MHYT domain
AOR13_RS15180	COG0625	glutathione transferase activity
AOR13_RS15185	COG0281	malic enzyme
AOR13_RS15190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOR13_RS15225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOR13_RS15235	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AOR13_RS15255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOR13_RS15260	COG0180	Tryptophanyl-tRNA synthetase
AOR13_RS15265	COG0512	Glutamine amidotransferase of anthranilate synthase
AOR13_RS15275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOR13_RS15285	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS15310	COG4999	Histidine kinase
AOR13_RS15310	COG3850	Histidine kinase
AOR13_RS15310	COG2205	protein histidine kinase activity
AOR13_RS15310	COG3437	response regulator, receiver
AOR13_RS15335	COG0540	Belongs to the ATCase OTCase family
AOR13_RS15350	COG2837	iron assimilation
AOR13_RS15355	COG0405	Gamma-glutamyltransferase
AOR13_RS15360	COG0004	ammonium transporteR
AOR13_RS15385	COG2354	Protein conserved in bacteria
AOR13_RS15395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOR13_RS15405	COG2951	lytic endotransglycosylase activity
AOR13_RS15410	COG1643	Atp-dependent helicase
AOR13_RS15420	COG0788	formyltetrahydrofolate deformylase activity
AOR13_RS15455	COG1519	Transferase
AOR13_RS15460	COG0859	PFAM glycosyl transferase family 9
AOR13_RS15465	COG0438	transferase activity, transferring glycosyl groups
AOR13_RS15470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOR13_RS15485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOR13_RS15495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOR13_RS15505	COG0089	rRNA binding
AOR13_RS15520	COG0051	transcription antitermination factor activity, RNA binding
AOR13_RS15525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOR13_RS15545	COG1454	alcohol dehydrogenase
AOR13_RS15580	COG2211	Major facilitator Superfamily
AOR13_RS15590	COG0673	inositol 2-dehydrogenase activity
AOR13_RS15595	COG1609	Transcriptional regulator
AOR13_RS15655	COG0501	Belongs to the peptidase M48B family
AOR13_RS15670	COG2201	protein-glutamate methylesterase activity
AOR13_RS15675	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AOR13_RS15690	COG0835	chemotaxis
AOR13_RS15695	COG0643	Histidine kinase
AOR13_RS15695	COG2198	Histidine kinase
AOR13_RS15700	COG0745	RESPONSE REGULATOR receiver
AOR13_RS15755	COG1194	a g-specific adenine glycosylase
AOR13_RS15765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOR13_RS15775	COG0297	glycogen (starch) synthase activity
AOR13_RS15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_RS15780	COG4191	Histidine kinase
AOR13_RS15785	COG0745	RESPONSE REGULATOR receiver
AOR13_RS15800	COG0312	modulator of DNA gyrase
AOR13_RS15805	COG3028	Belongs to the UPF0307 family
AOR13_RS15815	COG0312	modulator of DNA gyrase
AOR13_RS15820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_RS15830	COG1530	ribonuclease E activity
AOR13_RS15840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOR13_RS15845	COG1792	Involved in formation and maintenance of cell shape
AOR13_RS15850	COG1077	Cell shape determining protein MreB Mrl
AOR13_RS15875	COG2165	general secretion pathway protein
AOR13_RS15880	COG2165	general secretion pathway protein
AOR13_RS15890	COG1459	type II secretion system
AOR13_RS15895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOR13_RS15905	COG3267	Type II secretory pathway component ExeA
AOR13_RS15905	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_RS15945	COG1349	DNA-binding transcription factor activity
AOR13_RS15970	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_RS16000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_RS16010	COG0745	RESPONSE REGULATOR receiver
AOR13_RS16025	COG4615	Cyclic peptide transporter
AOR13_RS16045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_RS16055	COG3710	Transcriptional regulator
AOR13_RS16095	COG0629	single-stranded DNA binding
AOR13_RS16105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOR13_RS16110	COG1085	galactose-1-phosphate uridylyltransferase
AOR13_RS16130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_RS16135	COG2814	Major facilitator Superfamily
AOR13_RS16140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOR13_RS16165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOR13_RS16175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOR13_RS16180	COG0163	prenyltransferase activity
AOR13_RS16210	COG0019	diaminopimelate decarboxylase activity
AOR13_RS16215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOR13_RS16230	COG1011	Hydrolase
AOR13_RS16250	COG2962	Rard protein
AOR13_RS16255	COG2239	Acts as a magnesium transporter
AOR13_RS16260	COG2050	protein possibly involved in aromatic compounds catabolism
AOR13_RS16265	COG0514	ATP-dependent DNA helicase (RecQ)
AOR13_RS16275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOR13_RS16285	COG5002	protein histidine kinase activity
AOR13_RS16285	COG5001	Diguanylate cyclase
AOR13_RS16290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOR13_RS16295	COG3064	Membrane
AOR13_RS16305	COG0840	transmembrane signaling receptor activity
AOR13_RS16315	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOR13_RS16320	COG0427	acetyl-CoA hydrolase
AOR13_RS16330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_RS16335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS16360	COG0583	DNA-binding transcription factor activity
AOR13_RS16370	COG5001	Diguanylate cyclase
AOR13_RS16370	COG5002	protein histidine kinase activity
AOR13_RS16370	COG3447	MASE1 domain protein
AOR13_RS16395	COG0668	transmembrane transport
AOR13_RS16400	COG2081	HI0933 family
AOR13_RS16405	COG3842	ATPase activity
AOR13_RS16410	COG1178	ABC-type Fe3 transport system permease component
AOR13_RS16430	COG0678	peroxiredoxin activity
AOR13_RS16430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_RS16440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOR13_RS16445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOR13_RS16455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOR13_RS16465	COG0194	GDP metabolic process
AOR13_RS16480	COG0181	hydroxymethylbilane synthase activity
AOR13_RS16490	COG2959	enzyme of heme biosynthesis
AOR13_RS16495	COG3071	HemY protein
AOR13_RS16505	COG1953	Uracil, thiamine, allantoin
AOR13_RS16530	COG1309	transcriptional regulator
AOR13_RS16535	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOR13_RS16540	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOR13_RS16545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOR13_RS16555	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AOR13_RS16555	COG0778	Nitroreductase
AOR13_RS16565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOR13_RS16570	COG4771	TonB-dependent receptor
AOR13_RS16585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOR13_RS16600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOR13_RS16620	COG3106	COG3106 Predicted ATPase
AOR13_RS16635	COG0583	DNA-binding transcription factor activity
AOR13_RS16640	COG1960	acyl-CoA dehydrogenase activity
AOR13_RS16650	COG0842	Transport permease protein
AOR13_RS16655	COG1129	ABC transporter
AOR13_RS16655	COG0842	Transport permease protein
AOR13_RS16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_RS16675	COG0583	DNA-binding transcription factor activity
AOR13_RS16680	COG4773	Receptor
AOR13_RS16685	COG4999	Histidine kinase
AOR13_RS16685	COG3850	Histidine kinase
AOR13_RS16685	COG3437	response regulator, receiver
AOR13_RS16685	COG2205	protein histidine kinase activity
AOR13_RS16690	COG0457	Tetratricopeptide repeat
AOR13_RS16695	COG4771	TonB-dependent receptor
AOR13_RS16700	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS16710	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_RS16715	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS16730	COG0583	DNA-binding transcription factor activity
AOR13_RS16735	COG1760	l-serine dehydratase
AOR13_RS16775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOR13_RS16790	COG4638	Rieske (2fe-2S)
AOR13_RS16810	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_RS16810	COG1902	pentaerythritol trinitrate reductase activity
AOR13_RS16815	COG0247	lactate metabolic process
AOR13_RS16815	COG2181	nitrate reductase activity
AOR13_RS16830	COG1620	l-lactate permease
AOR13_RS16835	COG0556	nucleotide-excision repair
AOR13_RS16845	COG0326	Molecular chaperone. Has ATPase activity
AOR13_RS16865	COG1757	Na H antiporter
AOR13_RS16875	COG0653	protein targeting
AOR13_RS16895	COG0210	DNA helicase
AOR13_RS16900	COG2960	long-chain fatty acid transporting porin activity
AOR13_RS16905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOR13_RS16910	COG3161	chorismate lyase activity
AOR13_RS16920	COG0705	Rhomboid family
AOR13_RS16925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOR13_RS16935	COG0156	8-amino-7-oxononanoate synthase activity
AOR13_RS16955	COG0859	PFAM glycosyl transferase family 9
AOR13_RS16960	COG3642	lipopolysaccharide core region biosynthetic process
AOR13_RS17000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_RS17025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOR13_RS17040	COG2234	aminopeptidase activity
AOR13_RS17060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOR13_RS17145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOR13_RS17160	COG3047	cAMP biosynthetic process
AOR13_RS17165	COG0408	coproporphyrinogen oxidase activity
AOR13_RS17170	COG0009	L-threonylcarbamoyladenylate synthase
AOR13_RS17185	COG0758	DNA mediated transformation
AOR13_RS17205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOR13_RS17205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOR13_RS17210	COG0569	domain protein
AOR13_RS17215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOR13_RS17220	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AOR13_RS17225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOR13_RS17225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOR13_RS17240	COG3078	GTPase activator activity
AOR13_RS17250	COG2818	Glycosylase
AOR13_RS17275	COG0187	DNA topoisomerase II activity
AOR13_RS17280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOR13_RS17295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOR13_RS17300	COG0594	ribonuclease P activity
AOR13_RS17305	COG0706	membrane insertase activity
AOR13_RS17315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOR13_RS17320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOR13_RS17345	COG1192	Involved in chromosome partitioning
AOR13_RS17350	COG1475	DNA binding
AOR13_RS17370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOR13_RS17375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOR13_RS17395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOR13_RS17425	COG2199	diguanylate cyclase activity
AOR13_RS17425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AOR13_RS17440	COG1609	Transcriptional regulator
AOR13_RS17445	COG2211	Major facilitator Superfamily
AOR13_RS17450	COG2723	6-phospho-beta-galactosidase activity
AOR13_RS17480	COG1561	YicC-like family, N-terminal region
AOR13_RS17495	COG0425	Belongs to the sulfur carrier protein TusA family
AOR13_RS17545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOR13_RS17565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOR13_RS17575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOR13_RS17600	COG2911	Protein conserved in bacteria
AOR13_RS17605	COG0729	surface antigen
AOR13_RS17615	COG2814	Major facilitator Superfamily
AOR13_RS17630	COG0606	chelatase, subunit chli
AOR13_RS17645	COG0129	dihydroxy-acid dehydratase activity
AOR13_RS17675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOR13_RS17675	COG1565	acr, cog1565
AOR13_RS17680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOR13_RS17685	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AOR13_RS17710	COG1612	heme a metabolic process
AOR13_RS17715	COG0109	protoheme IX farnesyltransferase activity
AOR13_RS17720	COG1999	signal sequence binding
AOR13_RS17735	COG0534	Mate efflux family protein
AOR13_RS17740	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AOR13_RS17755	COG1794	racemase activity, acting on amino acids and derivatives
AOR13_RS17775	COG1040	competence protein
AOR13_RS17780	COG0596	Alpha beta hydrolase
AOR13_RS17795	COG2183	response to ionizing radiation
AOR13_RS17800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOR13_RS17810	COG0545	Peptidyl-prolyl cis-trans isomerase
AOR13_RS17835	COG0488	(ABC) transporter
AOR13_RS17845	COG0429	hydrolase of the alpha beta-hydrolase fold
AOR13_RS17850	COG3089	Belongs to the UPF0270 family
AOR13_RS17860	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AOR13_RS17865	COG2943	transferase activity, transferring hexosyl groups
AOR13_RS17875	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOR13_RS17880	COG0494	nUDIX hydrolase
AOR13_RS17885	COG1011	Hydrolase
AOR13_RS17895	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS17900	COG1234	tRNA 3'-trailer cleavage
AOR13_RS17910	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AOR13_RS17925	COG4795	General secretion pathway protein
AOR13_RS17930	COG2165	general secretion pathway protein
AOR13_RS17940	COG2165	general secretion pathway protein
AOR13_RS17945	COG1459	type II secretion system
AOR13_RS17950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOR13_RS17960	COG3031	protein transport across the cell outer membrane
AOR13_RS17970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOR13_RS17975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AOR13_RS18005	COG2233	PERMEase
AOR13_RS18010	COG3954	Phosphoribulokinase
AOR13_RS18020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOR13_RS18030	COG0151	Belongs to the GarS family
AOR13_RS18045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOR13_RS18050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_RS18065	COG0154	amidase activity
AOR13_RS18085	COG2176	DNA-directed DNA polymerase activity
AOR13_RS18105	COG0439	Biotin carboxylase
AOR13_RS18110	COG0511	ligase activity, forming carbon-carbon bonds
AOR13_RS18115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOR13_RS18120	COG0739	heme binding
AOR13_RS18125	COG4232	protein-disulfide reductase activity
AOR13_RS18155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_RS18175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOR13_RS18185	COG1166	arginine decarboxylase activity
AOR13_RS18195	COG4977	sequence-specific DNA binding
AOR13_RS18200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOR13_RS18205	COG0697	spore germination
AOR13_RS18220	COG1349	DNA-binding transcription factor activity
AOR13_RS18225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOR13_RS18245	COG4771	TonB-dependent receptor
AOR13_RS18260	COG0523	cobalamin synthesis protein
AOR13_RS18280	COG4181	ATPase activity
AOR13_RS18290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOR13_RS18310	COG3706	GGDEF domain
AOR13_RS18310	COG5001	Diguanylate cyclase
AOR13_RS18310	COG4251	negative regulation of phosphorylation
AOR13_RS18310	COG2203	Gaf domain
AOR13_RS18315	COG2130	NADP-dependent
AOR13_RS18320	COG2067	long-chain fatty acid transport protein
AOR13_RS18345	COG1252	NADH dehydrogenase
AOR13_RS18350	COG2353	YceI-like domain
AOR13_RS18355	COG3038	cytochrome b561
AOR13_RS18380	COG2267	carboxylic ester hydrolase activity
AOR13_RS18405	COG1404	Belongs to the peptidase S8 family
AOR13_RS18425	COG3237	CsbD-like
AOR13_RS18465	COG4319	ketosteroid isomerase
AOR13_RS18490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOR13_RS18525	COG2204	response regulator
AOR13_RS18540	COG1294	oxidase, subunit
AOR13_RS18550	COG4988	ABC transporter
AOR13_RS18555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOR13_RS18560	COG4771	TonB-dependent receptor
AOR13_RS18595	COG1230	cation diffusion facilitator family transporter
AOR13_RS18600	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_RS18615	COG2188	Transcriptional regulator
AOR13_RS18620	COG0656	L-ascorbic acid biosynthetic process
AOR13_RS18625	COG2175	clavaminate synthase activity
AOR13_RS18630	COG2855	membrane
AOR13_RS18645	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_RS18655	COG4206	TonB-dependent receptor
AOR13_RS18665	COG4558	Periplasmic binding protein
AOR13_RS18670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOR13_RS18675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOR13_RS18685	COG2723	6-phospho-beta-galactosidase activity
AOR13_RS18690	COG2211	Major facilitator Superfamily
AOR13_RS18695	COG1609	Transcriptional regulator
AOR13_RS18705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_RS18705	COG4191	Histidine kinase
AOR13_RS18720	COG5002	protein histidine kinase activity
AOR13_RS18750	COG2258	MOSC domain
AOR13_RS18775	COG0305	Participates in initiation and elongation during chromosome replication
AOR13_RS18795	COG0735	belongs to the Fur family
AOR13_RS18800	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AOR13_RS18805	COG2816	NAD+ diphosphatase activity
AOR13_RS18820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOR13_RS18825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOR13_RS18825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOR13_RS18830	COG0802	atpase or kinase
AOR13_RS18845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOR13_RS18850	COG1923	regulation of RNA biosynthetic process
AOR13_RS18855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOR13_RS18860	COG0330	HflC and HflK could
AOR13_RS18865	COG0330	HflC and HflK could
AOR13_RS18870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOR13_RS18875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOR13_RS18890	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_RS18900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOR13_RS18905	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AOR13_RS18920	COG0625	glutathione transferase activity
AOR13_RS18935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_RS18945	COG1793	dna ligase
AOR13_RS18955	COG1201	RNA secondary structure unwinding
AOR13_RS18960	COG3306	glycosyltransferase involved in LPS biosynthesis
AOR13_RS18975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_RS18980	COG2957	Belongs to the agmatine deiminase family
AOR13_RS19000	COG0302	gtp cyclohydrolase
AOR13_RS19015	COG0346	lactoylglutathione lyase activity
AOR13_RS19020	COG4989	oxidoreductase activity
AOR13_RS19025	COG3040	lipid binding
AOR13_RS19035	COG0418	dihydroorotase activity
AOR13_RS19040	COG0513	Belongs to the DEAD box helicase family
AOR13_RS19050	COG3590	peptidase
AOR13_RS19055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOR13_RS19060	COG1132	(ABC) transporter
AOR13_RS19070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOR13_RS19075	COG0250	Participates in transcription elongation, termination and antitermination
AOR13_RS19080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOR13_RS19085	COG0081	regulation of translation
AOR13_RS19090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOR13_RS19095	COG0222	ribosome binding
AOR13_RS19100	COG0085	RNA polymerase activity
AOR13_RS19105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOR13_RS19110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOR13_RS19115	COG0049	tRNA binding
AOR13_RS19120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOR13_RS19160	COG0657	acetylesterase activity
AOR13_RS19175	COG1966	Carbon starvation protein
AOR13_RS19180	COG0701	Predicted permease
AOR13_RS19185	COG1253	flavin adenine dinucleotide binding
AOR13_RS19205	COG4774	siderophore transport
AOR13_RS19210	COG2205	protein histidine kinase activity
AOR13_RS19215	COG0745	RESPONSE REGULATOR receiver
AOR13_RS19220	COG1131	(ABC) transporter
AOR13_RS19225	COG0842	Transport permease protein
AOR13_RS19235	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AOR13_RS19240	COG0076	glutamate decarboxylase activity
AOR13_RS19255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOR13_RS19265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOR13_RS19270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOR13_RS19290	COG2095	MarC family integral membrane protein
AOR13_RS19300	COG0742	ribosomal rna small subunit methyltransferase
AOR13_RS19305	COG0552	protein localization to endoplasmic reticulum
AOR13_RS19310	COG2884	Cell division ATP-binding protein ftsE
AOR13_RS19315	COG2177	Part of the ABC transporter FtsEX involved in
AOR13_RS19320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_RS19325	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_RS19335	COG0456	acetyltransferase
AOR13_RS19365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOR13_RS19370	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AOR13_RS19375	COG0281	malic enzyme
AOR13_RS19390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOR13_RS19395	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOR13_RS19400	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AOR13_RS19440	COG0793	Belongs to the peptidase S41A family
AOR13_RS19440	COG4946	Tricorn protease homolog
AOR13_RS19445	COG0243	molybdopterin cofactor binding
AOR13_RS19450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_RS19470	COG2201	protein-glutamate methylesterase activity
AOR13_RS19475	COG0339	signal peptide processing
AOR13_RS19495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOR13_RS19500	COG1278	Cold shock
AOR13_RS19515	COG1522	sequence-specific DNA binding
AOR13_RS19520	COG0840	transmembrane signaling receptor activity
AOR13_RS19525	COG1294	oxidase, subunit
AOR13_RS19530	COG1271	oxidase subunit
AOR13_RS19550	COG2234	aminopeptidase activity
AOR13_RS19555	COG0543	2 iron, 2 sulfur cluster binding
AOR13_RS19570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AOR13_RS19585	COG0557	exoribonuclease II activity
AOR13_RS19590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOR13_RS19605	COG5002	protein histidine kinase activity
AOR13_RS19605	COG0784	Response regulator, receiver
AOR13_RS19640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOR13_RS19660	COG0201	protein transport
AOR13_RS19680	COG0202	RNA polymerase activity
AOR13_RS19690	COG0662	Cupin 2, conserved barrel domain protein
AOR13_RS19690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AOR13_RS19695	COG0438	transferase activity, transferring glycosyl groups
AOR13_RS19695	COG1216	Glycosyl transferase, family 2
AOR13_RS19710	COG3119	arylsulfatase activity
AOR13_RS19725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AOR13_RS19750	COG0438	transferase activity, transferring glycosyl groups
AOR13_RS19750	COG1216	Glycosyl transferase, family 2
AOR13_RS19810	COG0583	DNA-binding transcription factor activity