locus-tag	class	description
H3L97_RS00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H3L97_RS00020	ENOG4105D7T	ABC transporter
H3L97_RS00030	ENOG4105I5W	Transporter
H3L97_RS00040	ENOG4108W2Y	isochorismatase
H3L97_RS00065	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H3L97_RS00070	ENOG4105E9S	glutaredoxin 2
H3L97_RS00080	ENOG4108YZY	peptidylprolyl cis-trans isomerase
H3L97_RS00085	ENOG4107UWN	reductase
H3L97_RS00125	ENOG4105DJ0	Poly(A) Polymerase
H3L97_RS00130	ENOG4105Z2P	Protein of unknown function (DUF465)
H3L97_RS00155	ENOG4105K4H	Nlp p60 protein
H3L97_RS00165	ENOG4107RZZ	dna polymerase iii epsilon subunit
H3L97_RS00195	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
H3L97_RS00305	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
H3L97_RS00320	ENOG4105EHM	Aminoglycoside phosphotransferase
H3L97_RS00330	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
H3L97_RS00335	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
H3L97_RS00340	ENOG4105CYB	regulatoR
H3L97_RS00345	ENOG4105CJ2	(LipO)protein
H3L97_RS00355	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
H3L97_RS00365	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
H3L97_RS00380	ENOG4105NVB	glycoside hydrolase, family 19
H3L97_RS00390	ENOG4105EAB	amino acid AbC transporter
H3L97_RS00395	ENOG4105E0U	tyrosine-specific transport protein
H3L97_RS00400	ENOG4105C0F	tryptophanase EC 4.1.99.1
H3L97_RS00435	ENOG4108X4Q	Hydrolase
H3L97_RS00465	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
H3L97_RS00475	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
H3L97_RS00480	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
H3L97_RS00495	ENOG4105VKD	bioY protein
H3L97_RS00550	ENOG4106TNF	Periplasmic binding protein
H3L97_RS00560	ENOG4105CKK	Glycosyl transferase, family 2
H3L97_RS00585	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
H3L97_RS00595	ENOG4105DDQ	anthranilate synthase
H3L97_RS00600	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
H3L97_RS00610	ENOG4108URH	decarboxylase
H3L97_RS00625	ENOG4105C4R	Atp-dependent dna helicase
H3L97_RS00685	ENOG4105DFP	Integrase
H3L97_RS00695	ENOG4105NTZ	Preprotein translocase subunit SecG
H3L97_RS00710	ENOG4108V2W	Carbonate dehydratase
H3L97_RS00715	ENOG4105CSM	endonuclease III
H3L97_RS00720	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
H3L97_RS00730	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
H3L97_RS00735	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
H3L97_RS00740	ENOG4105D9N	nucleoside
H3L97_RS00745	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
H3L97_RS00750	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
H3L97_RS00755	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
H3L97_RS00765	ENOG4108I0Z	Aconitate hydratase
H3L97_RS00815	ENOG4105BZN	citrate synthase
H3L97_RS00830	ENOG4105CR4	methylisocitrate lyase
H3L97_RS00840	ENOG4105C7F	AcnD-accessory protein PrpF
H3L97_RS00845	ENOG41090JD	Blue (Type 1) copper domain protein
H3L97_RS00850	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3L97_RS00855	ENOG4105F38	ABC transporter, permease
H3L97_RS00860	ENOG4105D38	putrescine abc transporter
H3L97_RS00905	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H3L97_RS00910	ENOG4107S1Q	Phosphatase
H3L97_RS00920	ENOG4105EX9	Membrane
H3L97_RS00955	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H3L97_RS00970	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
H3L97_RS00980	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H3L97_RS00985	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H3L97_RS01075	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H3L97_RS01080	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
H3L97_RS01110	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L97_RS01160	ENOG4105JAB	phenazine biosynthesis protein, phzf family
H3L97_RS01165	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H3L97_RS01175	ENOG4108ZIT	Ferredoxin, 2FE-2S
H3L97_RS01215	ENOG4108IJ6	ABC transporter
H3L97_RS01230	ENOG4105ECW	sulfate abc transporter
H3L97_RS01235	ENOG4108I5D	sulfate abc transporter
H3L97_RS01240	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H3L97_RS01250	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
H3L97_RS01275	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3L97_RS01290	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H3L97_RS01305	ENOG4105C2I	pirin domain protein
H3L97_RS01315	ENOG4107QP8	phosphohexose isomerase
H3L97_RS01360	ENOG4105VW4	glutaredoxin 3
H3L97_RS01385	ENOG4105EN6	Membrane
H3L97_RS01400	ENOG4105CC0	LysR family Transcriptional regulator
H3L97_RS01415	ENOG4105D5T	phosphonate abc transporter
H3L97_RS01450	ENOG4105C59	p-type ATPase
H3L97_RS01455	ENOG4105IBP	Cyclic peptide transporter
H3L97_RS01470	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H3L97_RS01485	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3L97_RS01490	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H3L97_RS01500	ENOG4108UJV	acyl-CoA thioesterase i
H3L97_RS01540	ENOG4105CQ7	ATP-dependent helicase
H3L97_RS01545	ENOG4105VGJ	Virulence-associated protein
H3L97_RS01570	ENOG4108RH0	Crea protein
H3L97_RS01580	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
H3L97_RS01585	ENOG4105K59	histidine triad (HIT) protein
H3L97_RS01600	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H3L97_RS01605	ENOG4105DIK	(ABC) transporter
H3L97_RS01615	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H3L97_RS01625	ENOG4105C25	Primosomal protein n'
H3L97_RS01640	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H3L97_RS01670	ENOG4105KJF	protein tyrosine phosphatase
H3L97_RS01675	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H3L97_RS01680	ENOG4105CC5	ABC transporter
H3L97_RS01705	ENOG4105DSE	periplasmic solute binding protein
H3L97_RS01725	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H3L97_RS01745	ENOG4105DQR	SNARE associated Golgi
H3L97_RS01775	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
H3L97_RS01805	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H3L97_RS01865	ENOG4105DIN	metallophosphoesterase
H3L97_RS01870	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
H3L97_RS01880	ENOG4106ZV1	Transferrin binding protein-like solute binding protein
H3L97_RS01885	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
H3L97_RS01890	ENOG4105CKI	cobalamin synthesis protein
H3L97_RS01900	ENOG4106NDP	Transcriptional regulator
H3L97_RS01925	ENOG4105C1J	atp-dependent rna helicase
H3L97_RS01930	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H3L97_RS01945	ENOG4108HPI	phosphatidate Cytidylyltransferase
H3L97_RS01980	ENOG4105X0D	Fimbrial protein
H3L97_RS01995	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
H3L97_RS02015	ENOG4107653	Transcriptional regulator
H3L97_RS02035	ENOG4108PPJ	Type II restriction
H3L97_RS02065	ENOG4105CF7	AraC family transcriptional regulator
H3L97_RS02070	ENOG4108IXY	short-chain dehydrogenase reductase
H3L97_RS02075	ENOG4108QD6	
H3L97_RS02080	ENOG4105C02	permease
H3L97_RS02095	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H3L97_RS02120	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H3L97_RS02135	ENOG4105MA0	exported protein
H3L97_RS02145	ENOG4105CFU	surface antigen
H3L97_RS02230	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
H3L97_RS02290	ENOG4105EA8	2-Nitropropane dioxygenase
H3L97_RS02305	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H3L97_RS02310	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
H3L97_RS02325	ENOG4107QR9	Iron-sulfur cluster binding protein
H3L97_RS02335	ENOG4107IIZ	CRISPR-associated helicase, Cas3
H3L97_RS02340	ENOG4105ENG	CRISPR-associated protein, Csy1 family
H3L97_RS02345	ENOG4105DZX	CRISPR-associated protein, Csy2 family
H3L97_RS02385	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
H3L97_RS02415	ENOG4108V1U	phospholipid-binding protein
H3L97_RS02420	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H3L97_RS02425	ENOG4108XC3	NADH ubiquinone oxidoreductase
H3L97_RS02460	ENOG4105C10	Electron transfer flavoprotein
H3L97_RS02465	ENOG4105BZJ	Electron transfer flavoprotein
H3L97_RS02470	ENOG4105D16	lipopolysaccharide heptosyltransferase i
H3L97_RS02485	ENOG4105BZ1	(ABC) transporter
H3L97_RS02505	ENOG4105K8R	UPF0145 protein
H3L97_RS02510	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H3L97_RS02555	ENOG4108S2Y	peptide Chain Release factor
H3L97_RS02580	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
H3L97_RS02590	ENOG4108VMM	UPF0756 membrane protein
H3L97_RS02595	ENOG4105EAH	synthase
H3L97_RS02600	ENOG4105CAK	Cell division ATP-binding protein ftsE
H3L97_RS02605	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
H3L97_RS02665	ENOG4105C2M	dna polymerase I
H3L97_RS02670	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
H3L97_RS02675	ENOG4106H78	methyltransferase
H3L97_RS02680	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
H3L97_RS02725	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H3L97_RS02760	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H3L97_RS02795	ENOG4105K5B	UPF0225 protein
H3L97_RS02800	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS02815	ENOG4105EW9	transcriptional regulator AsnC family
H3L97_RS02860	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H3L97_RS02875	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H3L97_RS02965	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H3L97_RS03025	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H3L97_RS03035	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H3L97_RS03075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3L97_RS03090	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
H3L97_RS03110	ENOG4105DSY	exodeoxyribonuclease V, gamma
H3L97_RS03125	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
H3L97_RS03135	ENOG4105K63	Thioredoxin
H3L97_RS03140	ENOG4107RK2	ADP-ribose diphosphatase NudE
H3L97_RS03145	ENOG4106KNT	transcriptional regulator
H3L97_RS03150	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
H3L97_RS03155	ENOG4108R96	Methyltransferase, YaeB family
H3L97_RS03165	ENOG4105MJ2	Competence protein
H3L97_RS03170	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H3L97_RS03180	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H3L97_RS03185	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
H3L97_RS03195	ENOG4107VDP	teichoic acid biosynthesis
H3L97_RS03205	ENOG4108RWI	nicotinamidase
H3L97_RS03210	ENOG4105CJR	Integral membrane protein (MviN
H3L97_RS03230	ENOG4108Z0R	Transferase
H3L97_RS03245	ENOG4108UHU	Aldolase
H3L97_RS03260	ENOG4105UGU	tonB-dependent Receptor
H3L97_RS03280	ENOG4105EQ2	LysR family Transcriptional regulator
H3L97_RS03285	ENOG4105KVH	Transcriptional regulator
H3L97_RS03295	ENOG4105MGM	doxx family
H3L97_RS03305	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H3L97_RS03330	ENOG4105C01	Dihydroxy-acid dehydratase
H3L97_RS03365	ENOG4105DTN	riboflavin biosynthesis protein ribF
H3L97_RS03370	ENOG4105EAD	ABC transporter
H3L97_RS03385	ENOG4105CKK	Glycosyl transferase, family 2
H3L97_RS03390	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
H3L97_RS03405	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H3L97_RS03415	ENOG4105DR9	pseudouridine synthase
H3L97_RS03425	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H3L97_RS03435	ENOG4108M0I	Transcriptional regulator
H3L97_RS03455	ENOG4105II7	pyrroline-5-carboxylate reductase
H3L97_RS03465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
H3L97_RS03480	ENOG4105CD8	aminopeptidase N
H3L97_RS03495	ENOG4105KNE	Phosphatidate cytidylyltransferase
H3L97_RS03500	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H3L97_RS03530	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
H3L97_RS03565	ENOG4105DZ2	Transcriptional regulator
H3L97_RS03570	ENOG4108Z03	MAF-like protein
H3L97_RS03615	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H3L97_RS03670	ENOG4105KD1	integral membrane protein
H3L97_RS03675	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H3L97_RS03680	ENOG4105C7N	Xanthine uracil vitamin C permease
H3L97_RS03700	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3L97_RS03730	ENOG4108R0G	Tetratricopeptide repeat protein
H3L97_RS03770	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H3L97_RS03775	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H3L97_RS03845	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H3L97_RS03880	ENOG4105GKE	subunit e
H3L97_RS03890	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
H3L97_RS03910	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
H3L97_RS03925	ENOG4105DF2	NADH dehydrogenase subunit j
H3L97_RS03965	ENOG4105C8S	subunit m
H3L97_RS03975	ENOG4105D52	delta-aminolevulinic acid dehydratase
H3L97_RS03990	ENOG4105CSR	polyphosphate kinase 2
H3L97_RS04010	ENOG4105BZG	amino acid carrier protein
H3L97_RS04015	ENOG4105C5I	Dehydrogenase
H3L97_RS04025	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
H3L97_RS04045	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H3L97_RS04075	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L97_RS04085	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
H3L97_RS04100	ENOG4105CRE	cytochrome C
H3L97_RS04110	ENOG4108R3D	Electron transport complex
H3L97_RS04155	ENOG4105EMU	Dehydrogenase
H3L97_RS04160	ENOG4105KA7	cytochrome C
H3L97_RS04170	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3L97_RS04190	ENOG4105C0H	protease
H3L97_RS04210	ENOG4105C5X	domain protein
H3L97_RS04230	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H3L97_RS04240	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
H3L97_RS04270	ENOG4105CVE	Lytic murein transglycosylase
H3L97_RS04280	ENOG4105D3Y	Na H antiporter
H3L97_RS04285	ENOG4105DFA	alanine racemase domain protein
H3L97_RS04300	ENOG4105DNZ	Alpha Beta Hydrolase
H3L97_RS04360	ENOG4105DR4	Methyltransferase
H3L97_RS04380	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H3L97_RS04390	ENOG4105VEQ	Cold shock protein
H3L97_RS04400	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3L97_RS04405	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H3L97_RS04410	ENOG4105E0K	tonB-dependent siderophore receptor
H3L97_RS04415	ENOG4105E0A	ABC, transporter
H3L97_RS04425	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
H3L97_RS04440	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
H3L97_RS04460	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
H3L97_RS04470	ENOG4105DJ4	phosphatidylserine decarboxylase
H3L97_RS04475	ENOG4106E5D	Protein of unknown function (DUF461)
H3L97_RS04480	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
H3L97_RS04490	ENOG41064T2	transcriptional regulator, lysR family
H3L97_RS04575	ENOG4105EQ2	LysR family Transcriptional regulator
H3L97_RS04595	ENOG4105EQ2	LysR family Transcriptional regulator
H3L97_RS04600	ENOG4105NF4	modulator of drug activity
H3L97_RS04610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3L97_RS04615	ENOG4105DEN	Luciferase family
H3L97_RS04620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3L97_RS04625	ENOG4108RCM	Nitroreductase
H3L97_RS04640	ENOG4105DQ4	alcohol dehydrogenase
H3L97_RS04720	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H3L97_RS04765	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
H3L97_RS04825	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
H3L97_RS04830	ENOG4105D1H	recombination factor protein RarA
H3L97_RS04865	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
H3L97_RS04875	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H3L97_RS04880	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H3L97_RS04885	ENOG41077RS	Phosphatase
H3L97_RS04895	ENOG4105EGS	Mechanosensitive ion channel
H3L97_RS04900	ENOG4108TIT	dATP pyrophosphohydrolase
H3L97_RS04915	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L97_RS04990	ENOG4105E4C	Lytic transglycosylase catalytic
H3L97_RS04995	ENOG4108YXU	transcriptional regulator AsnC family
H3L97_RS05005	ENOG4105K3M	)-transporter
H3L97_RS05010	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
H3L97_RS05015	ENOG4105DWF	phosphomethylpyrimidine kinase
H3L97_RS05025	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
H3L97_RS05030	ENOG4105DC1	bifunctional purine biosynthesis protein purh
H3L97_RS05110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3L97_RS05125	ENOG4105C2W	permease
H3L97_RS05130	ENOG4105MSB	protein, conserved in bacteria
H3L97_RS05140	ENOG410650H	(LipO)protein
H3L97_RS05160	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3L97_RS05165	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3L97_RS05170	ENOG4105EIX	cytochrome c1
H3L97_RS05175	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H3L97_RS05250	ENOG4105EYK	Phosphatidylglycerophosphatase B
H3L97_RS05260	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H3L97_RS05270	ENOG4105DR5	peptidase
H3L97_RS05275	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H3L97_RS05290	ENOG4105DB7	PHP domain protein
H3L97_RS05295	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
H3L97_RS05300	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H3L97_RS05315	ENOG4105C28	cystathionine
H3L97_RS05320	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L97_RS05325	ENOG4105WVQ	Fe-S assembly protein IscX
H3L97_RS05335	ENOG4105EI2	Pseudouridine synthase
H3L97_RS05340	ENOG4105C03	ribonuclease
H3L97_RS05350	ENOG41060A7	DNA polymerase beta domain protein region
H3L97_RS05355	ENOG41062MS	nucleotidyltransferase substrate binding protein
H3L97_RS05380	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H3L97_RS05390	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
H3L97_RS05395	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3L97_RS05410	ENOG4107QSI	ABC, transporter
H3L97_RS05435	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
H3L97_RS05445	ENOG4105D2N	Aldolase
H3L97_RS05485	ENOG4108ZAI	phosphatidylglycerophosphatase a
H3L97_RS05495	ENOG4105DGW	oligopeptidase A
H3L97_RS05510	ENOG4108JQ7	(ABC) transporter
H3L97_RS05515	ENOG4105C3U	ABC transporter
H3L97_RS05520	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3L97_RS05525	ENOG4105QYV	Membrane
H3L97_RS05530	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
H3L97_RS05540	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3L97_RS05580	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
H3L97_RS05630	ENOG4105FKN	transcriptional regulator, AsnC family
H3L97_RS05635	ENOG4106KPZ	rard protein
H3L97_RS05670	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H3L97_RS05695	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H3L97_RS05705	ENOG4108JU5	Magnesium and cobalt efflux protein
H3L97_RS05710	ENOG4105C3F	Signal peptidase i
H3L97_RS05715	ENOG4105QNF	Outer membrane lipoprotein
H3L97_RS05735	ENOG4108JQC	penicillin-binding protein 1A
H3L97_RS05770	ENOG4105F27	Major Facilitator
H3L97_RS05780	ENOG4105E5Q	amino acid AbC transporter
H3L97_RS05785	ENOG4105CDA	abc transporter atp-binding protein
H3L97_RS05790	ENOG4105C5H	ABC transporter
H3L97_RS05800	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H3L97_RS05805	ENOG4105K4I	Scp-like extracellular
H3L97_RS05810	ENOG4107RP9	extracellular solute-binding protein, family 3
H3L97_RS05820	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H3L97_RS05825	ENOG4105C9X	ppx gppa phosphatase
H3L97_RS05835	ENOG4105CKW	Inner membrane protein yedI
H3L97_RS05845	ENOG4105C3M	thioredoxin reductase
H3L97_RS05855	ENOG4105EAB	amino acid AbC transporter
H3L97_RS05865	ENOG4105W0Z	cytoplasmic protein
H3L97_RS05870	ENOG4105C0P	Mg chelatase subunit ChlI
H3L97_RS05890	ENOG4105EKE	dihydroorotase
H3L97_RS05900	ENOG4105C26	Dehydrogenase
H3L97_RS05905	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H3L97_RS05920	ENOG4105W5Q	DNA repair protein (RadC
H3L97_RS05925	ENOG4108K0D	peptidase, M48
H3L97_RS05930	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
H3L97_RS05955	ENOG4105EVN	Prephenate dehydrogenase
H3L97_RS06005	ENOG4107QM2	Aldo Keto reductase
H3L97_RS06015	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H3L97_RS06020	ENOG4105CBS	Chea signal transduction histidine kinase
H3L97_RS06025	ENOG4107YTP	response regulator receiver protein
H3L97_RS06040	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H3L97_RS06065	ENOG4105VUC	UPF0237 protein
H3L97_RS06070	ENOG4105CXG	d-lactate dehydrogenase
H3L97_RS06085	ENOG4105CAG	UPF0210 protein
H3L97_RS06095	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H3L97_RS06110	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H3L97_RS06125	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H3L97_RS06140	ENOG4105FE9	pseudouridine synthase
H3L97_RS06145	ENOG4105C28	cystathionine
H3L97_RS06155	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H3L97_RS06160	ENOG4105C94	Transporter
H3L97_RS06170	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H3L97_RS06180	ENOG4105CTB	Polyprenyl synthetase
H3L97_RS06185	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H3L97_RS06190	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
H3L97_RS06200	ENOG4105E7A	Glutamine amidotransferase
H3L97_RS06220	ENOG4105CC5	ABC transporter
H3L97_RS06225	ENOG4105CC5	ABC transporter
H3L97_RS06235	ENOG4105DIK	(ABC) transporter
H3L97_RS06245	ENOG4105BZG	amino acid carrier protein
H3L97_RS06250	ENOG4105D6U	Sodium Glutamate Symporter
H3L97_RS06255	ENOG4105C3G	gtp-binding protein
H3L97_RS06285	ENOG4105CX6	glutaminyL-tRNA synthetase
H3L97_RS06290	ENOG4105CIN	aminoacyl-histidine dipeptidase
H3L97_RS06300	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H3L97_RS06305	ENOG4105CT7	inner membrane cred family protein
H3L97_RS06310	ENOG4105FE9	pseudouridine synthase
H3L97_RS06315	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H3L97_RS06320	ENOG4105F0S	class B acid phosphatase
H3L97_RS06325	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
H3L97_RS06355	ENOG4107QMP	dna polymerase iii subunits gamma and tau
H3L97_RS06360	ENOG4105CD5	CoA-binding domain protein
H3L97_RS06385	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H3L97_RS06400	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H3L97_RS06410	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H3L97_RS06420	ENOG4108KDT	Molybdate metabolism regulator
H3L97_RS06445	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
H3L97_RS06460	ENOG4105DEG	Vwa containing coxe family protein
H3L97_RS06480	ENOG4105CGF	Aromatic amino acid aminotransferase
H3L97_RS06500	ENOG4105CEP	NADH dehydrogenase
H3L97_RS06505	ENOG4105C5A	transporter
H3L97_RS06520	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
H3L97_RS06525	ENOG4105VTW	prevent-host-death family
H3L97_RS06540	ENOG4107R7A	Allophanate hydrolase subunit 2
H3L97_RS06545	ENOG4105P4J	Allophanate hydrolase, subunit 1
H3L97_RS06550	ENOG4105C26	Dehydrogenase
H3L97_RS06565	ENOG4105EAC	phosphoserine phosphatase
H3L97_RS06570	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
H3L97_RS06585	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
H3L97_RS06600	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
H3L97_RS06605	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H3L97_RS06610	ENOG4105K64	Glycosyl transferase, family 2
H3L97_RS06620	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H3L97_RS06625	ENOG4105K8N	protein family UPF0079, ATPase
H3L97_RS06635	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3L97_RS06640	ENOG4105DP0	ferredoxin-NADP reductase
H3L97_RS06645	ENOG4105VEJ	Heat shock protein
H3L97_RS06660	ENOG4105DSJ	YicC domain protein
H3L97_RS06670	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H3L97_RS06690	ENOG4105XPH	Ferredoxin
H3L97_RS06695	ENOG4105E12	capsule polysaccharide
H3L97_RS06705	ENOG4105C58	cytochrome c oxidase accessory protein ccog
H3L97_RS06715	ENOG4105C6K	Malic enzyme
H3L97_RS06735	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
H3L97_RS06740	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3L97_RS06750	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3L97_RS06770	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H3L97_RS06780	ENOG4105F8V	Hydrolase, tatD family
H3L97_RS06790	ENOG4107QRG	dna polymerase iii
H3L97_RS06795	ENOG4107TH8	cina domain protein
H3L97_RS06805	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
H3L97_RS06830	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H3L97_RS06835	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
H3L97_RS06840	ENOG4105D4T	Citrate transporter
H3L97_RS06870	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H3L97_RS06885	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H3L97_RS06890	ENOG4105CDU	Replicative dna helicase
H3L97_RS06920	ENOG4105C75	arginyL-tRNA synthetase
H3L97_RS06925	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
H3L97_RS06935	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H3L97_RS06995	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L97_RS07000	ENOG4107TUY	Histidine kinase
H3L97_RS07005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3L97_RS07015	ENOG4107QTF	adenylosuccinate lyase
H3L97_RS07020	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS07030	ENOG4108004	Modulates RecA activity (By similarity)
H3L97_RS07040	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3L97_RS07045	ENOG4105CBC	glutamate synthase
H3L97_RS07050	ENOG4105DAA	L-lactate
H3L97_RS07070	ENOG4107S76	domain protein
H3L97_RS07085	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L97_RS07095	ENOG4105WD1	Membrane
H3L97_RS07100	ENOG4107TF3	peptidylprolyl cis-trans isomerase
H3L97_RS07105	ENOG4105VFK	BolA family
H3L97_RS07110	ENOG4105K9H	YciI-like protein
H3L97_RS07135	ENOG4105CEN	a g-specific adenine glycosylase
H3L97_RS07170	ENOG4109045	doxx family
H3L97_RS07175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3L97_RS07180	ENOG4105ES5	Histidine kinase
H3L97_RS07190	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H3L97_RS07215	ENOG4105CPF	Cell wall formation (By similarity)
H3L97_RS07220	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
H3L97_RS07225	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H3L97_RS07245	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
H3L97_RS07280	ENOG4105C7B	Threonine dehydratase
H3L97_RS07290	ENOG4105DZ1	carboxypeptidase
H3L97_RS07300	ENOG4105CHM	Aminotransferase
H3L97_RS07305	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H3L97_RS07330	ENOG4108JPW	Aminotransferase
H3L97_RS07340	ENOG4105DY8	decarboxylase
H3L97_RS07355	ENOG4105C5H	ABC transporter
H3L97_RS07365	ENOG4107QK7	reductase
H3L97_RS07375	ENOG410807V	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
H3L97_RS07395	ENOG4105HBR	Rna-binding protein
H3L97_RS07400	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
H3L97_RS07405	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H3L97_RS07415	ENOG4107YTP	response regulator receiver protein
H3L97_RS07420	ENOG4105CBS	Chea signal transduction histidine kinase
H3L97_RS07430	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H3L97_RS07470	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
H3L97_RS07480	ENOG4105CJN	penicillin-binding protein
H3L97_RS07485	ENOG4105CNI	cell division protein FtsW
H3L97_RS07495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H3L97_RS07500	ENOG4108RRZ	Transcription elongation factor GreB
H3L97_RS07510	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS07515	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
H3L97_RS07520	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
H3L97_RS07545	ENOG4105KME	endoribonuclease L-psp
H3L97_RS07555	ENOG4105ECY	inositol monophosphatase
H3L97_RS07560	ENOG4105FR1	rard protein
H3L97_RS07590	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H3L97_RS07605	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H3L97_RS07615	ENOG4107ZVW	dihydroneopterin aldolase
H3L97_RS07625	ENOG4105XA0	heptosyltransferase ii
H3L97_RS07635	ENOG4105CFV	Tetratricopeptide repeat protein
H3L97_RS07655	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H3L97_RS07660	ENOG4105CZX	twitching motility protein
H3L97_RS07665	ENOG4105CZX	twitching motility protein
H3L97_RS07670	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L97_RS07675	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H3L97_RS07680	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H3L97_RS07685	ENOG4105D4P	Coproporphyrinogen iii oxidase
H3L97_RS07690	ENOG4105C6T	cysteine synthase
H3L97_RS07700	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
H3L97_RS07705	ENOG4107QPK	)-transporter
H3L97_RS07710	ENOG4105DEF	Extracellular solute-binding protein, family 5
H3L97_RS07715	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3L97_RS07720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3L97_RS07725	ENOG4105C3U	ABC transporter
H3L97_RS07735	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
H3L97_RS07740	ENOG4108TZV	Membrane
H3L97_RS07760	ENOG4105D6E	homoserine dehydrogenase
H3L97_RS07770	ENOG4108UJU	UPF0301 protein
H3L97_RS07780	ENOG4105C5H	ABC transporter
H3L97_RS07815	ENOG4105WPN	DNA integration recombination invertion protein
H3L97_RS07820	ENOG4106YJS	accessory processing protein
H3L97_RS07825	ENOG4109066	lysm domain bon superfamily protein
H3L97_RS07835	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H3L97_RS07850	ENOG4105CQB	FAD linked oxidase domain protein
H3L97_RS07860	ENOG41069NU	Nitroreductase
H3L97_RS07865	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H3L97_RS07900	ENOG4105D3G	Pseudouridine synthase
H3L97_RS07905	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H3L97_RS07910	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
H3L97_RS07915	ENOG4105C4R	Atp-dependent dna helicase
H3L97_RS07940	ENOG41061WM	D-Alanyl-D-Alanine
H3L97_RS07945	ENOG4107S74	Lysophospholipid transporter LplT
H3L97_RS07975	ENOG4105DJV	ribulose-phosphate 3-epimerase
H3L97_RS08015	ENOG4105DWT	malate dehydrogenase (quinone)
H3L97_RS08020	ENOG4105CNU	cell division protein FtsK
H3L97_RS08025	ENOG4105CFH	Aspartokinase
H3L97_RS08030	ENOG4105CK7	Sodium proline symporter
H3L97_RS08045	ENOG4108Z1B	Cyclase dehydrase
H3L97_RS08050	ENOG4105CSA	Coproporphyrinogen iii oxidase
H3L97_RS08060	ENOG4107RDB	Major Facilitator
H3L97_RS08075	ENOG4105DJF	DNA polymerase III, delta' subunit
H3L97_RS08095	ENOG4107QN1	sodium solute
H3L97_RS08100	ENOG4108K5P	(LipO)protein
H3L97_RS08105	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
H3L97_RS08110	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3L97_RS08135	ENOG4107RZC	phospholipase d
H3L97_RS08150	ENOG4107QIJ	Aconitate hydratase 2
H3L97_RS08160	ENOG4105E53	ec 3.2.1.28
H3L97_RS08165	ENOG4105FFC	UPF0187 protein
H3L97_RS08175	ENOG4105EJQ	L-serine dehydratase
H3L97_RS08195	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H3L97_RS08220	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
H3L97_RS08230	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
H3L97_RS08235	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
H3L97_RS08240	ENOG4108JA2	transcriptioN-repair coupling factor
H3L97_RS08245	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H3L97_RS08250	ENOG4107QSN	dihydrolipoamide acetyltransferase
H3L97_RS08270	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H3L97_RS08275	ENOG4108YYH	Nadph-dependent fmn reductase
H3L97_RS08295	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H3L97_RS08305	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H3L97_RS08310	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H3L97_RS08315	ENOG4107QKA	exodeoxyribonuclease V beta
H3L97_RS08340	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS08345	ENOG4105E9K	Isocitrate dehydrogenase
H3L97_RS08355	ENOG4108XI2	Domain of unknown function (DUF1963)
H3L97_RS08360	ENOG4105CN1	protease
H3L97_RS08370	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
H3L97_RS08375	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H3L97_RS08405	ENOG4107YCY	Transcriptional regulator
H3L97_RS08410	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
H3L97_RS08420	ENOG4105DIA	mandelate racemase muconate lactonizing
H3L97_RS08430	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H3L97_RS08460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H3L97_RS08495	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H3L97_RS08525	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS08545	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H3L97_RS08570	ENOG4108VW9	Membrane
H3L97_RS08575	ENOG4105C8Y	Acetylornithine aminotransferase
H3L97_RS08590	ENOG4105CZX	twitching motility protein
H3L97_RS08600	ENOG4108YSG	O-Antigen polymerase
H3L97_RS08605	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H3L97_RS08610	ENOG4105E0F	Histidine kinase
H3L97_RS08620	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
H3L97_RS08625	ENOG41080IJ	Diacylglycerol kinase
H3L97_RS08630	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H3L97_RS08640	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H3L97_RS08650	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
H3L97_RS08655	ENOG4105DWV	Homoserine O-trans-acetylase
H3L97_RS08665	ENOG4105DWV	Homoserine O-trans-acetylase
H3L97_RS08670	ENOG4105I08	Pseudouridine synthase
H3L97_RS08680	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H3L97_RS08690	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
H3L97_RS08700	ENOG4105CUV	Homoserine Kinase
H3L97_RS08715	ENOG4105D7W	serine acetyltransferase
H3L97_RS08735	ENOG4105CGF	Aromatic amino acid aminotransferase
H3L97_RS08740	ENOG4105F8V	Hydrolase, tatD family
H3L97_RS08745	ENOG4108Z4V	iron-sulfur cluster assembly
H3L97_RS08750	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
H3L97_RS08785	ENOG4105CGK	Exodeoxyribonuclease III
H3L97_RS08790	ENOG4105DGU	Histone deacetylase
H3L97_RS08805	ENOG4105JKW	Valine--pyruvate aminotransferase
H3L97_RS08810	ENOG4105DVT	helicase
H3L97_RS08815	ENOG4105DFU	Cell wall formation (By similarity)
H3L97_RS08870	ENOG4105DY2	Paraquat-inducible protein b
H3L97_RS08875	ENOG4105F1S	paraquat-inducible protein a
H3L97_RS08880	ENOG4108VD1	dedA family
H3L97_RS08885	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
H3L97_RS08895	ENOG4108ZP8	Acetolactate synthase small subunit
H3L97_RS08900	ENOG4105C7K	acetolactate synthase
H3L97_RS08910	ENOG4108ZUW	Major pilin subunit
H3L97_RS08920	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H3L97_RS08935	ENOG4105C9A	Phoh family
H3L97_RS08950	ENOG4105CUT	histidyl-tRNA synthetase
H3L97_RS08965	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H3L97_RS08970	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS09000	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
H3L97_RS09010	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H3L97_RS09020	ENOG4105CQ0	ABC transporter
H3L97_RS09055	ENOG4106D9H	
H3L97_RS09060	ENOG4105HDK	L-asparaginase
H3L97_RS09070	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
H3L97_RS09075	ENOG4108DNC	Involved in acetate metabolism (By similarity)
H3L97_RS09085	ENOG4107RK0	Sucrose phosphorylase
H3L97_RS09090	ENOG4108YZ4	nudix hydrolase
H3L97_RS09105	ENOG4105C1J	atp-dependent rna helicase
H3L97_RS09110	ENOG4108EC8	DNA internalization-related competence protein ComEC
H3L97_RS09115	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS09120	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3L97_RS09135	ENOG4107MKT	Stringent starvation protein a
H3L97_RS09140	ENOG4105KB2	stringent starvation protein b
H3L97_RS09165	ENOG4105ECX	polysaccharide export
H3L97_RS09175	ENOG4105EE5	Membrane protein terC
H3L97_RS09185	ENOG4105DWU	Membrane
H3L97_RS09190	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3L97_RS09245	ENOG4108N0M	stress protein
H3L97_RS09260	ENOG41067MG	lrgb family
H3L97_RS09270	ENOG4105CSH	Transporter
H3L97_RS09275	ENOG4108K5P	(LipO)protein
H3L97_RS09280	ENOG4105SYT	Methylenetetrahydrofolate reductase
H3L97_RS09285	ENOG4105C5H	ABC transporter
H3L97_RS09290	ENOG4105HHA	aminodeoxychorismate lyase
H3L97_RS09310	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L97_RS09315	ENOG4105CEY	Amp-dependent synthetase and ligase
H3L97_RS09320	ENOG4107QYX	exodeoxyribonuclease v alpha
H3L97_RS09330	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H3L97_RS09335	ENOG4105FE1	phytoene synthase
H3L97_RS09340	ENOG4107S11	squalene-associated FAD-dependent desaturase
H3L97_RS09345	ENOG4105UBK	short-chain dehydrogenase reductase
H3L97_RS09355	ENOG4105CJW	magnesium transporter
H3L97_RS09365	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3L97_RS09375	ENOG4105CGH	5'-nucleotidase
H3L97_RS09385	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H3L97_RS09390	ENOG4105EM2	membrane
H3L97_RS09400	ENOG4105C7S	Dehydrogenase
H3L97_RS09415	ENOG4105EPR	degv family
H3L97_RS09420	ENOG4105C1A	potassium transporter peripheral membrane
H3L97_RS09430	ENOG4108JJA	ABC, transporter
H3L97_RS09445	ENOG4105CH2	amidohydrolase
H3L97_RS09475	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H3L97_RS09490	ENOG4108R99	pseudouridine synthase
H3L97_RS09515	ENOG4105E33	succinate dehydrogenase
H3L97_RS09520	ENOG410681N	tpr repeat protein
H3L97_RS09525	ENOG4105BZN	citrate synthase
H3L97_RS09535	ENOG4105D6Z	AFG1 family ATPase
H3L97_RS09565	ENOG4105E9H	Lytic Murein transglycosylase
H3L97_RS09575	ENOG4105HDD	phospholipase
H3L97_RS09590	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
H3L97_RS09655	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
H3L97_RS09660	ENOG4105D1S	lipid A biosynthesis
H3L97_RS09665	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3L97_RS09680	ENOG4105IPS	esterase
H3L97_RS09720	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
H3L97_RS09725	ENOG4108NIW	Leucine export protein LeuE
H3L97_RS09740	ENOG4107S78	Band 7 protein
H3L97_RS09800	ENOG4105C5E	polysaccharide biosynthesis protein
H3L97_RS09810	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H3L97_RS09830	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H3L97_RS09840	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3L97_RS09845	ENOG4105F7F	Chaperone
H3L97_RS09860	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H3L97_RS09870	ENOG4108YZA	Nitrogen regulatory protein pii
H3L97_RS09880	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H3L97_RS09885	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS09890	ENOG4108HWV	)-transporter
H3L97_RS09895	ENOG4105C2J	ABC transporter
H3L97_RS09905	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
H3L97_RS09915	ENOG4107QJE	Chromosome Partitioning Protein
H3L97_RS09925	ENOG4105F0R	Cytidylyltransferase
H3L97_RS09935	ENOG4105VDT	-acetyltransferase
H3L97_RS09940	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H3L97_RS09960	ENOG4108MY6	biosynthesis protein
H3L97_RS09975	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
H3L97_RS09990	ENOG4108RYC	glycosyltransferase
H3L97_RS10005	ENOG4107YTP	response regulator receiver protein
H3L97_RS10020	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H3L97_RS10030	ENOG4108EKN	Biotin protein ligase C terminal domain
H3L97_RS10035	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
H3L97_RS10040	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3L97_RS10045	ENOG4108IUZ	ABC transporter
H3L97_RS10050	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
H3L97_RS10060	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
H3L97_RS10065	ENOG4105C2X	Arabinose 5-phosphate isomerase
H3L97_RS10080	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
H3L97_RS10085	ENOG4105D82	Glutamate dehydrogenase
H3L97_RS10090	ENOG4105C8P	)-transporter
H3L97_RS10095	ENOG4108ZG0	Ompa motb domain protein
H3L97_RS10100	ENOG4105C2C	drug resistance transporter, Bcr CflA
H3L97_RS10110	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
H3L97_RS10115	ENOG4105W1T	Glycosyl Transferase
H3L97_RS10130	ENOG4105EYM	Major Facilitator superfamily
H3L97_RS10135	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H3L97_RS10145	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H3L97_RS10160	ENOG4105D6S	protein involved in catabolism of external DNA
H3L97_RS10190	ENOG4108IPW	abc transporter atp-binding protein
H3L97_RS10195	ENOG4105K56	Transcriptional regulator
H3L97_RS10200	ENOG4105CM4	permease protein
H3L97_RS10210	ENOG4105DHS	permease protein
H3L97_RS10220	ENOG4108Z12	YiaAB two helix domain-containing protein
H3L97_RS10250	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H3L97_RS10255	ENOG4105M4H	endoribonuclease L-psp
H3L97_RS10265	ENOG4108HM4	ABC transporter
H3L97_RS10270	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H3L97_RS10280	ENOG4105E7U	AraC family transcriptional regulator
H3L97_RS10290	ENOG4108XTF	Outer Membrane Lipoprotein
H3L97_RS10305	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H3L97_RS10345	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H3L97_RS10360	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H3L97_RS10365	ENOG4105C8J	)-transporter
H3L97_RS10375	ENOG4105C8J	)-transporter
H3L97_RS10440	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H3L97_RS10445	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H3L97_RS10460	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
H3L97_RS10465	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H3L97_RS10470	ENOG4105C5F	glutamine synthetase
H3L97_RS10475	ENOG4105D01	(LipO)protein
H3L97_RS10510	ENOG4108UMI	ABC transporter, permease
H3L97_RS10530	ENOG4105ECY	inositol monophosphatase
H3L97_RS10535	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H3L97_RS10550	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
H3L97_RS10570	ENOG4108I6E	Sulfatase
H3L97_RS10585	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H3L97_RS10590	ENOG4107QQ0	gntp family
H3L97_RS10595	ENOG4105BZW	Glycerate kinase
H3L97_RS10630	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H3L97_RS10635	ENOG4105BZS	acriflavin resistance protein
H3L97_RS10640	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H3L97_RS10645	ENOG4108IG5	Transcriptional regulator
H3L97_RS10650	ENOG4105C03	ribonuclease
H3L97_RS10715	ENOG4105C26	Dehydrogenase
H3L97_RS10725	ENOG4108QD6	
H3L97_RS10750	ENOG4105BZ1	(ABC) transporter
H3L97_RS10765	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H3L97_RS10770	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
H3L97_RS10840	ENOG4105DFP	Integrase
H3L97_RS10890	ENOG4107R3N	Filamentation induced by cAMP protein fic
H3L97_RS10900	ENOG4105DHQ	Histidine kinase
H3L97_RS10930	ENOG4105C3R	Methionine synthase
H3L97_RS10935	ENOG4105D5Q	Arginine ornithine antiporter
H3L97_RS10955	ENOG4107R11	Transcriptional regulator
H3L97_RS10960	ENOG4105CB5	ATP-dependent DNA helicase recG
H3L97_RS10965	ENOG4108BMY	protease
H3L97_RS10970	ENOG4108BMY	protease
H3L97_RS10995	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
H3L97_RS11000	ENOG4105F0N	pyrophosphate phospho-hydrolase
H3L97_RS11010	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H3L97_RS11020	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H3L97_RS11030	ENOG4105UYK	outer membrane protein a
H3L97_RS11040	ENOG4105DP0	ferredoxin-NADP reductase
H3L97_RS11050	ENOG4105C26	Dehydrogenase
H3L97_RS11055	ENOG4105DUX	Transporter
H3L97_RS11060	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
H3L97_RS11070	ENOG4107QHF	type ii secretion system protein e
H3L97_RS11075	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H3L97_RS11080	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
H3L97_RS11120	ENOG4105CA9	Pyruvate kinase
H3L97_RS11140	ENOG4108S0S	Nucleotidyl transferase
H3L97_RS11145	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H3L97_RS11185	ENOG4107QMS	site-determining protein
H3L97_RS11195	ENOG4105C5Q	Transcriptional regulator
H3L97_RS11215	ENOG4107SC1	transglycosylase
H3L97_RS11255	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H3L97_RS11285	ENOG4105CT1	(ABC) transporter
H3L97_RS11290	ENOG4105CDA	abc transporter atp-binding protein
H3L97_RS11295	ENOG4105E5Q	amino acid AbC transporter
H3L97_RS11300	ENOG4105E5Q	amino acid AbC transporter
H3L97_RS11305	ENOG4108UKZ	OsmC family
H3L97_RS11320	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H3L97_RS11325	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H3L97_RS11330	ENOG4108Z6B	deaminase
H3L97_RS11350	ENOG4108R6K	riboflavin synthase, subunit alpha
H3L97_RS11360	ENOG4105D2S	major facilitator superfamily
H3L97_RS11370	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H3L97_RS11395	ENOG4105CI3	gtp-binding protein typa
H3L97_RS11410	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
H3L97_RS11415	ENOG4105ED9	Protein of unknown function (DUF455)
H3L97_RS11420	ENOG4105NSG	hemerythrin hhe cation binding domain protein
H3L97_RS11430	ENOG4108U51	Universal stress protein
H3L97_RS11435	ENOG4105CUZ	uba thif-type nad fad binding protein
H3L97_RS11440	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H3L97_RS11460	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H3L97_RS11470	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H3L97_RS11505	ENOG4105CHV	Transcription elongation factor NusA
H3L97_RS11520	ENOG4105C59	p-type ATPase
H3L97_RS11530	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
H3L97_RS11535	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
H3L97_RS11540	ENOG4105C6Z	Gluconate
H3L97_RS11545	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3L97_RS11550	ENOG4105DS1	cytochrome b561
H3L97_RS11570	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H3L97_RS11575	ENOG4105Y3U	Transglycosylase-associated protein
H3L97_RS11580	ENOG4105CGZ	zinc metallopeptidase
H3L97_RS11590	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H3L97_RS11630	ENOG4105CHR	reductase
H3L97_RS11640	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3L97_RS11650	ENOG4106IWJ	hemolysin
H3L97_RS11670	ENOG4106PMH	Extracellular solute-binding protein family 3
H3L97_RS11685	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H3L97_RS11705	ENOG4105DHJ	ABC, transporter
H3L97_RS11710	ENOG4105CY3	ABC transporter, permease
H3L97_RS11715	ENOG4107PE3	Mammalian cell entry related domain protein
H3L97_RS11740	ENOG4108TGP	Thioesterase superfamily protein
H3L97_RS11760	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
H3L97_RS11770	ENOG4105CFP	Peptidase U32
H3L97_RS11795	ENOG41072GX	Peptidase M22 Glycoprotease