locus-tag	class	description
A9CBEGH2_RS00005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A9CBEGH2_RS00020	COG0463	Glycosyl transferase, family 2
A9CBEGH2_RS00025	COG2246	polysaccharide biosynthetic process
A9CBEGH2_RS00030	COG1682	transport, permease protein
A9CBEGH2_RS00035	COG1134	teichoic acid transport
A9CBEGH2_RS00045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A9CBEGH2_RS00050	COG1216	Glycosyl transferase, family 2
A9CBEGH2_RS00055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A9CBEGH2_RS00075	COG0463	Glycosyl transferase, family 2
A9CBEGH2_RS00105	COG0058	SHG alpha-glucan phosphorylase activity
A9CBEGH2_RS00110	COG1523	belongs to the glycosyl hydrolase 13 family
A9CBEGH2_RS00115	COG1307	EDD domain protein, DegV family
A9CBEGH2_RS00120	COG1307	EDD domain protein, DegV family
A9CBEGH2_RS00125	COG4447	cellulose binding
A9CBEGH2_RS00140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9CBEGH2_RS00145	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A9CBEGH2_RS00150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A9CBEGH2_RS00155	COG0492	ferredoxin-NADP+ reductase activity
A9CBEGH2_RS00160	COG1917	Cupin 2, conserved barrel domain protein
A9CBEGH2_RS00160	COG2207	Transcriptional regulator
A9CBEGH2_RS00170	COG1940	carbohydrate kinase activity
A9CBEGH2_RS00180	COG2272	Belongs to the type-B carboxylesterase lipase family
A9CBEGH2_RS00190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9CBEGH2_RS00200	COG2050	protein possibly involved in aromatic compounds catabolism
A9CBEGH2_RS00225	COG1396	sequence-specific DNA binding
A9CBEGH2_RS00240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9CBEGH2_RS00255	COG3344	reverse transcriptase
A9CBEGH2_RS00260	COG0534	Mate efflux family protein
A9CBEGH2_RS00270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9CBEGH2_RS00275	COG0561	phosphatase activity
A9CBEGH2_RS00285	COG1446	asparaginase
A9CBEGH2_RS00295	COG0726	polysaccharide deacetylase
A9CBEGH2_RS00300	COG0628	permease
A9CBEGH2_RS00310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9CBEGH2_RS00425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A9CBEGH2_RS00435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9CBEGH2_RS00470	COG1773	rubredoxin
A9CBEGH2_RS00470	COG1592	Rubrerythrin
A9CBEGH2_RS00480	COG1501	Belongs to the glycosyl hydrolase 31 family
A9CBEGH2_RS00495	COG1136	(ABC) transporter
A9CBEGH2_RS00495	COG0577	efflux transmembrane transporter activity
A9CBEGH2_RS00520	COG0488	(ABC) transporter
A9CBEGH2_RS00540	COG1924	4 iron, 4 sulfur cluster binding
A9CBEGH2_RS00580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9CBEGH2_RS00585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A9CBEGH2_RS00585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A9CBEGH2_RS00590	COG2365	Tyrosine phosphatase family
A9CBEGH2_RS00595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9CBEGH2_RS00600	COG1309	transcriptional regulator
A9CBEGH2_RS00615	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9CBEGH2_RS00635	COG0252	asparaginase activity
A9CBEGH2_RS00650	COG3620	sequence-specific DNA binding
A9CBEGH2_RS00655	COG0281	malic enzyme
A9CBEGH2_RS00660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9CBEGH2_RS00725	COG0116	Belongs to the methyltransferase superfamily
A9CBEGH2_RS00725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A9CBEGH2_RS00755	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9CBEGH2_RS00780	COG1115	amino acid carrier protein
A9CBEGH2_RS00785	COG1929	Belongs to the glycerate kinase type-1 family
A9CBEGH2_RS00790	COG0640	Transcriptional regulator
A9CBEGH2_RS00795	COG2217	Heavy metal translocating P-type atpase
A9CBEGH2_RS00805	COG0363	glucosamine-6-phosphate deaminase activity
A9CBEGH2_RS00810	COG0561	phosphatase activity
A9CBEGH2_RS00815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A9CBEGH2_RS00820	COG0561	phosphatase activity
A9CBEGH2_RS00835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9CBEGH2_RS00865	COG4804	nuclease activity
A9CBEGH2_RS00885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A9CBEGH2_RS00890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A9CBEGH2_RS00910	COG0564	pseudouridine synthase activity
A9CBEGH2_RS00915	COG2033	superoxide reductase activity
A9CBEGH2_RS00920	COG2084	Dehydrogenase
A9CBEGH2_RS00930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9CBEGH2_RS00960	COG1683	Conserved Protein
A9CBEGH2_RS00965	COG1674	ftsk spoiiie
A9CBEGH2_RS00970	COG2946	Replication initiation factor
A9CBEGH2_RS00985	COG0596	Alpha beta hydrolase
A9CBEGH2_RS01020	COG0741	lytic transglycosylase activity
A9CBEGH2_RS01020	COG0791	NLP P60 protein
A9CBEGH2_RS01030	COG1309	transcriptional regulator
A9CBEGH2_RS01045	COG5002	protein histidine kinase activity
A9CBEGH2_RS01070	COG1136	(ABC) transporter
A9CBEGH2_RS01075	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS01080	COG3850	Histidine kinase
A9CBEGH2_RS01080	COG5002	protein histidine kinase activity
A9CBEGH2_RS01095	COG1136	(ABC) transporter
A9CBEGH2_RS01100	COG1131	(ABC) transporter
A9CBEGH2_RS01160	COG0582	viral genome integration into host DNA
A9CBEGH2_RS01165	COG1420	regulation of RNA biosynthetic process
A9CBEGH2_RS01170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A9CBEGH2_RS01185	COG1228	amidohydrolase
A9CBEGH2_RS01195	COG0617	tRNA 3'-terminal CCA addition
A9CBEGH2_RS01205	COG0546	phosphoglycolate phosphatase activity
A9CBEGH2_RS01220	COG0484	heat shock protein binding
A9CBEGH2_RS01225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9CBEGH2_RS01225	COG1918	ferrous iron import across plasma membrane
A9CBEGH2_RS01230	COG1918	ferrous iron import across plasma membrane
A9CBEGH2_RS01230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9CBEGH2_RS01245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A9CBEGH2_RS01260	COG1098	S1 RNA binding domain
A9CBEGH2_RS01310	COG4989	oxidoreductase activity
A9CBEGH2_RS01315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A9CBEGH2_RS01320	COG0181	hydroxymethylbilane synthase activity
A9CBEGH2_RS01325	COG0113	porphobilinogen synthase activity
A9CBEGH2_RS01330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A9CBEGH2_RS01340	COG0519	Catalyzes the synthesis of GMP from XMP
A9CBEGH2_RS01350	COG0574	Belongs to the PEP-utilizing enzyme family
A9CBEGH2_RS01350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9CBEGH2_RS01370	COG1131	(ABC) transporter
A9CBEGH2_RS01375	COG0326	Molecular chaperone. Has ATPase activity
A9CBEGH2_RS01390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9CBEGH2_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
A9CBEGH2_RS01415	COG0768	penicillin binding
A9CBEGH2_RS01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A9CBEGH2_RS01425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9CBEGH2_RS01430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A9CBEGH2_RS01440	COG0180	Tryptophanyl-tRNA synthetase
A9CBEGH2_RS01445	COG1393	Belongs to the ArsC family
A9CBEGH2_RS01500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9CBEGH2_RS01510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9CBEGH2_RS01515	COG1181	Belongs to the D-alanine--D-alanine ligase family
A9CBEGH2_RS01520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9CBEGH2_RS01530	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A9CBEGH2_RS01550	COG0765	amino acid transport
A9CBEGH2_RS01575	COG0438	transferase activity, transferring glycosyl groups
A9CBEGH2_RS01580	COG3481	metal-dependent phosphohydrolase, HD sub domain
A9CBEGH2_RS01605	COG0564	pseudouridine synthase activity
A9CBEGH2_RS01690	COG2801	Transposase and inactivated derivatives
A9CBEGH2_RS01755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9CBEGH2_RS01760	COG1045	serine acetyltransferase
A9CBEGH2_RS01765	COG3142	Participates in the control of copper homeostasis
A9CBEGH2_RS01800	COG2205	protein histidine kinase activity
A9CBEGH2_RS01810	COG0534	Mate efflux family protein
A9CBEGH2_RS01835	COG0598	Magnesium transport protein CorA
A9CBEGH2_RS01870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A9CBEGH2_RS01885	COG0544	peptidyl-prolyl cis-trans isomerase activity
A9CBEGH2_RS01895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A9CBEGH2_RS01910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9CBEGH2_RS01925	COG4656	Part of a membrane complex involved in electron transport
A9CBEGH2_RS01930	COG4658	electron transport chain
A9CBEGH2_RS01940	COG4660	Part of a membrane complex involved in electron transport
A9CBEGH2_RS01945	COG4657	Part of a membrane complex involved in electron transport
A9CBEGH2_RS01950	COG2878	Part of a membrane complex involved in electron transport
A9CBEGH2_RS01955	COG2502	aspartate--ammonia ligase
A9CBEGH2_RS01960	COG0475	glutathione-regulated potassium exporter activity
A9CBEGH2_RS01980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A9CBEGH2_RS02000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A9CBEGH2_RS02020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A9CBEGH2_RS02025	COG2011	ABC-type metal ion transport system permease component
A9CBEGH2_RS02030	COG1464	Belongs to the NlpA lipoprotein family
A9CBEGH2_RS02040	COG0420	3'-5' exonuclease activity
A9CBEGH2_RS02045	COG0419	ATPase involved in DNA repair
A9CBEGH2_RS02050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A9CBEGH2_RS02105	COG1307	EDD domain protein, DegV family
A9CBEGH2_RS02140	COG0850	regulation of cytokinetic process
A9CBEGH2_RS02145	COG2894	cell division
A9CBEGH2_RS02155	COG1994	Peptidase M50
A9CBEGH2_RS02165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9CBEGH2_RS02165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9CBEGH2_RS02170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A9CBEGH2_RS02175	COG0237	dephospho-CoA kinase activity
A9CBEGH2_RS02180	COG3611	Membrane attachment protein
A9CBEGH2_RS02185	COG1484	DNA-dependent DNA replication
A9CBEGH2_RS02190	COG0205	6-phosphofructokinase activity
A9CBEGH2_RS02200	COG2309	aminopeptidase activity
A9CBEGH2_RS02205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A9CBEGH2_RS02220	COG1799	cell septum assembly
A9CBEGH2_RS02235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A9CBEGH2_RS02240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9CBEGH2_RS02245	COG0183	Belongs to the thiolase family
A9CBEGH2_RS02250	COG1960	acyl-CoA dehydrogenase activity
A9CBEGH2_RS02255	COG2086	electron transfer activity
A9CBEGH2_RS02260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A9CBEGH2_RS02265	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9CBEGH2_RS02270	COG1024	Enoyl-CoA hydratase
A9CBEGH2_RS02285	COG2801	Transposase and inactivated derivatives
A9CBEGH2_RS02325	COG3763	UPF0154 protein
A9CBEGH2_RS02330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9CBEGH2_RS02370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9CBEGH2_RS02380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9CBEGH2_RS02385	COG4472	Bacterial protein of unknown function (DUF965)
A9CBEGH2_RS02395	COG3906	Belongs to the UPF0473 family
A9CBEGH2_RS02400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A9CBEGH2_RS02405	COG0572	uridine kinase
A9CBEGH2_RS02410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9CBEGH2_RS02415	COG1596	polysaccharide export
A9CBEGH2_RS02415	COG1555	photosystem II stabilization
A9CBEGH2_RS02480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9CBEGH2_RS02565	COG1475	DNA binding
A9CBEGH2_RS02595	COG1802	Transcriptional regulator
A9CBEGH2_RS02595	COG4626	Terminase
A9CBEGH2_RS02605	COG0740	serine-type endopeptidase activity
A9CBEGH2_RS02705	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A9CBEGH2_RS02710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A9CBEGH2_RS02715	COG3842	ATPase activity
A9CBEGH2_RS02745	COG1466	dna polymerase III delta subunit
A9CBEGH2_RS02750	COG1760	l-serine dehydratase
A9CBEGH2_RS02765	COG0552	protein localization to endoplasmic reticulum
A9CBEGH2_RS02770	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A9CBEGH2_RS02775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A9CBEGH2_RS02780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9CBEGH2_RS02785	COG0587	DNA-directed DNA polymerase activity
A9CBEGH2_RS02790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A9CBEGH2_RS02795	COG2868	ribosomal protein
A9CBEGH2_RS02800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A9CBEGH2_RS02805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A9CBEGH2_RS02810	COG0708	Exodeoxyribonuclease III
A9CBEGH2_RS02815	COG0561	phosphatase activity
A9CBEGH2_RS02820	COG0632	four-way junction helicase activity
A9CBEGH2_RS02825	COG2255	four-way junction helicase activity
A9CBEGH2_RS02835	COG2323	membrane
A9CBEGH2_RS02840	COG2244	polysaccharide biosynthetic process
A9CBEGH2_RS02850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9CBEGH2_RS02850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9CBEGH2_RS02855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A9CBEGH2_RS02855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9CBEGH2_RS02860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9CBEGH2_RS02865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9CBEGH2_RS02875	COG1323	Belongs to the UPF0348 family
A9CBEGH2_RS02880	COG1399	metal-binding, possibly nucleic acid-binding protein
A9CBEGH2_RS02885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A9CBEGH2_RS02895	COG0195	Participates in both transcription termination and antitermination
A9CBEGH2_RS02900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A9CBEGH2_RS02910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A9CBEGH2_RS02915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A9CBEGH2_RS02920	COG0656	L-ascorbic acid biosynthetic process
A9CBEGH2_RS02925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9CBEGH2_RS02930	COG0488	(ABC) transporter
A9CBEGH2_RS02955	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A9CBEGH2_RS02960	COG0187	DNA topoisomerase II activity
A9CBEGH2_RS02965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9CBEGH2_RS02980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9CBEGH2_RS02990	COG0494	nUDIX hydrolase
A9CBEGH2_RS02995	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9CBEGH2_RS03005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9CBEGH2_RS03015	COG0697	spore germination
A9CBEGH2_RS03030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9CBEGH2_RS03070	COG1696	Membrane protein involved in D-alanine export
A9CBEGH2_RS03090	COG1595	DNA-templated transcription, initiation
A9CBEGH2_RS03100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A9CBEGH2_RS03110	COG1686	Belongs to the peptidase S11 family
A9CBEGH2_RS03115	COG2715	membrane protein required for spore maturation
A9CBEGH2_RS03120	COG0700	Nucleoside recognition
A9CBEGH2_RS03125	COG4251	negative regulation of phosphorylation
A9CBEGH2_RS03125	COG2203	Gaf domain
A9CBEGH2_RS03125	COG3706	GGDEF domain
A9CBEGH2_RS03125	COG5001	Diguanylate cyclase
A9CBEGH2_RS03130	COG1187	pseudouridine synthase activity
A9CBEGH2_RS03135	COG1131	(ABC) transporter
A9CBEGH2_RS03155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9CBEGH2_RS03160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A9CBEGH2_RS03170	COG1349	DNA-binding transcription factor activity
A9CBEGH2_RS03175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A9CBEGH2_RS03180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A9CBEGH2_RS03200	COG1702	phosphate starvation-inducible protein PhoH
A9CBEGH2_RS03205	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS03210	COG5002	protein histidine kinase activity
A9CBEGH2_RS03225	COG1283	sodium-dependent phosphate transmembrane transporter activity
A9CBEGH2_RS03230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A9CBEGH2_RS03240	COG0295	cytidine deaminase activity
A9CBEGH2_RS03245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A9CBEGH2_RS03250	COG1381	Involved in DNA repair and RecF pathway recombination
A9CBEGH2_RS03255	COG0423	glycine-tRNA ligase activity
A9CBEGH2_RS03260	COG0358	DNA primase activity
A9CBEGH2_RS03265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9CBEGH2_RS03275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A9CBEGH2_RS03280	COG0513	Belongs to the DEAD box helicase family
A9CBEGH2_RS03285	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A9CBEGH2_RS03300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9CBEGH2_RS03305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9CBEGH2_RS03310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9CBEGH2_RS03320	COG4537	Required for transformation and DNA binding
A9CBEGH2_RS03340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A9CBEGH2_RS03350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A9CBEGH2_RS03355	COG1160	GTP binding
A9CBEGH2_RS03360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A9CBEGH2_RS03365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9CBEGH2_RS03370	COG0776	regulation of translation
A9CBEGH2_RS03375	COG2738	Putative neutral zinc metallopeptidase
A9CBEGH2_RS03385	COG1307	EDD domain protein, DegV family
A9CBEGH2_RS03400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A9CBEGH2_RS03405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A9CBEGH2_RS03415	COG1695	Transcriptional regulator
A9CBEGH2_RS03420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A9CBEGH2_RS03450	COG1300	Membrane
A9CBEGH2_RS03465	COG0750	zinc metalloprotease
A9CBEGH2_RS03470	COG0497	DNA recombination
A9CBEGH2_RS03475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A9CBEGH2_RS03480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A9CBEGH2_RS03490	COG1722	exodeoxyribonuclease VII activity
A9CBEGH2_RS03500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9CBEGH2_RS03520	COG1131	(ABC) transporter
A9CBEGH2_RS03535	COG2270	Major facilitator Superfamily
A9CBEGH2_RS03545	COG1136	(ABC) transporter
A9CBEGH2_RS03550	COG2205	protein histidine kinase activity
A9CBEGH2_RS03555	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS03575	COG0196	riboflavin kinase activity
A9CBEGH2_RS03580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A9CBEGH2_RS03585	COG0596	Alpha beta hydrolase
A9CBEGH2_RS03595	COG0037	tRNA processing
A9CBEGH2_RS03610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A9CBEGH2_RS03615	COG0124	histidyl-tRNA synthetase
A9CBEGH2_RS03670	COG0110	maltose O-acetyltransferase activity
A9CBEGH2_RS03675	COG0667	Aldo Keto reductase
A9CBEGH2_RS03680	COG0495	leucyl-tRNA aminoacylation
A9CBEGH2_RS03740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9CBEGH2_RS03740	COG0493	'glutamate synthase
A9CBEGH2_RS03755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A9CBEGH2_RS03770	COG2271	Major facilitator Superfamily
A9CBEGH2_RS03775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A9CBEGH2_RS03785	COG0583	DNA-binding transcription factor activity
A9CBEGH2_RS03795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A9CBEGH2_RS03800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A9CBEGH2_RS03805	COG0351	phosphomethylpyrimidine kinase
A9CBEGH2_RS03805	COG0352	thiamine-phosphate diphosphorylase activity
A9CBEGH2_RS03810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9CBEGH2_RS03820	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A9CBEGH2_RS03830	COG0456	acetyltransferase
A9CBEGH2_RS03840	COG1349	DNA-binding transcription factor activity
A9CBEGH2_RS03845	COG1063	alcohol dehydrogenase
A9CBEGH2_RS03850	COG1105	Belongs to the carbohydrate kinase PfkB family
A9CBEGH2_RS03870	COG1125	glycine betaine transport
A9CBEGH2_RS03870	COG0517	IMP dehydrogenase activity
A9CBEGH2_RS03875	COG1732	Glycine betaine
A9CBEGH2_RS03885	COG1733	regulation of RNA biosynthetic process
A9CBEGH2_RS03895	COG1136	(ABC) transporter
A9CBEGH2_RS03900	COG5002	protein histidine kinase activity
A9CBEGH2_RS03905	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS03940	COG0531	amino acid
A9CBEGH2_RS03945	COG1362	aminopeptidase activity
A9CBEGH2_RS03960	COG1242	4 iron, 4 sulfur cluster binding
A9CBEGH2_RS03965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A9CBEGH2_RS03975	COG1011	Hydrolase
A9CBEGH2_RS04150	COG3728	DNA packaging
A9CBEGH2_RS04150	COG5484	DNA packaging
A9CBEGH2_RS04265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A9CBEGH2_RS04270	COG1187	pseudouridine synthase activity
A9CBEGH2_RS04275	COG2244	polysaccharide biosynthetic process
A9CBEGH2_RS04285	COG0367	asparagine synthase
A9CBEGH2_RS04300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9CBEGH2_RS04315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A9CBEGH2_RS04320	COG1609	Transcriptional regulator
A9CBEGH2_RS04335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9CBEGH2_RS04345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9CBEGH2_RS04350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A9CBEGH2_RS04355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9CBEGH2_RS04365	COG3620	sequence-specific DNA binding
A9CBEGH2_RS04390	COG1595	DNA-templated transcription, initiation
A9CBEGH2_RS04405	COG3620	sequence-specific DNA binding
A9CBEGH2_RS04410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9CBEGH2_RS04415	COG0613	PHP domain protein
A9CBEGH2_RS04425	COG1185	polyribonucleotide nucleotidyltransferase activity
A9CBEGH2_RS04430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A9CBEGH2_RS04440	COG0242	peptide deformylase activity
A9CBEGH2_RS04445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9CBEGH2_RS04450	COG0481	GTPase activity
A9CBEGH2_RS04455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A9CBEGH2_RS04475	COG0268	Binds directly to 16S ribosomal RNA
A9CBEGH2_RS04485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A9CBEGH2_RS04490	COG0575	Belongs to the CDS family
A9CBEGH2_RS04495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A9CBEGH2_RS04500	COG0233	cytoplasmic translational termination
A9CBEGH2_RS04505	COG0528	UMP kinase activity
A9CBEGH2_RS04510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A9CBEGH2_RS04515	COG0052	Belongs to the universal ribosomal protein uS2 family
A9CBEGH2_RS04520	COG4974	Belongs to the 'phage' integrase family
A9CBEGH2_RS04525	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A9CBEGH2_RS04530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9CBEGH2_RS04535	COG0758	DNA mediated transformation
A9CBEGH2_RS04565	COG0681	Belongs to the peptidase S26 family
A9CBEGH2_RS04570	COG0681	Belongs to the peptidase S26 family
A9CBEGH2_RS04575	COG0335	large ribosomal subunit rRNA binding
A9CBEGH2_RS04580	COG0336	Belongs to the RNA methyltransferase TrmD family
A9CBEGH2_RS04585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A9CBEGH2_RS04595	COG0228	four-way junction DNA binding
A9CBEGH2_RS04600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9CBEGH2_RS04605	COG2226	methyltransferase
A9CBEGH2_RS04615	COG0301	tRNA thio-modification
A9CBEGH2_RS04620	COG1104	cysteine desulfurase activity
A9CBEGH2_RS04625	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A9CBEGH2_RS04640	COG0612	Peptidase, M16
A9CBEGH2_RS04645	COG0612	Peptidase, M16
A9CBEGH2_RS04665	COG1744	ABC transporter substrate-binding protein PnrA-like
A9CBEGH2_RS04670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9CBEGH2_RS04675	COG1328	CTP reductase activity
A9CBEGH2_RS04690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9CBEGH2_RS04700	COG1692	metallophosphoesterase
A9CBEGH2_RS04715	COG1058	Belongs to the CinA family
A9CBEGH2_RS04715	COG1546	Belongs to the CinA family
A9CBEGH2_RS04720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A9CBEGH2_RS04740	COG3331	DNA recombination
A9CBEGH2_RS04745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9CBEGH2_RS04750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9CBEGH2_RS04765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9CBEGH2_RS04770	COG2226	methyltransferase
A9CBEGH2_RS04775	COG0799	negative regulation of ribosome biogenesis
A9CBEGH2_RS04780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A9CBEGH2_RS04790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9CBEGH2_RS04795	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A9CBEGH2_RS04800	COG1363	Peptidase, m42
A9CBEGH2_RS04835	COG1191	sigma factor activity
A9CBEGH2_RS04840	COG2172	sigma factor antagonist activity
A9CBEGH2_RS04845	COG1366	Belongs to the anti-sigma-factor antagonist family
A9CBEGH2_RS04855	COG1686	Belongs to the peptidase S11 family
A9CBEGH2_RS04920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9CBEGH2_RS04925	COG0719	Fe-S assembly protein
A9CBEGH2_RS04930	COG0396	ATPase activity
A9CBEGH2_RS04935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9CBEGH2_RS04955	COG0742	ribosomal rna small subunit methyltransferase
A9CBEGH2_RS04960	COG0772	Belongs to the SEDS family
A9CBEGH2_RS04965	COG0242	peptide deformylase activity
A9CBEGH2_RS04975	COG1408	metallophosphoesterase
A9CBEGH2_RS04985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9CBEGH2_RS04985	COG0072	phenylalanine-tRNA ligase activity
A9CBEGH2_RS04990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A9CBEGH2_RS05000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9CBEGH2_RS05050	COG0655	NAD(P)H dehydrogenase (quinone) activity
A9CBEGH2_RS05070	COG5002	protein histidine kinase activity
A9CBEGH2_RS05075	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS05105	COG3328	transposase activity
A9CBEGH2_RS05110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9CBEGH2_RS05125	COG0583	DNA-binding transcription factor activity
A9CBEGH2_RS05130	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS05135	COG2190	(PTS) system
A9CBEGH2_RS05135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS05135	COG1263	PTS System
A9CBEGH2_RS05150	COG0656	L-ascorbic acid biosynthetic process
A9CBEGH2_RS05170	COG3681	Belongs to the UPF0597 family
A9CBEGH2_RS05175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9CBEGH2_RS05180	COG0367	asparagine synthase
A9CBEGH2_RS05195	COG0251	oxidation-reduction process
A9CBEGH2_RS05215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A9CBEGH2_RS05220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9CBEGH2_RS05250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9CBEGH2_RS05260	COG1191	sigma factor activity
A9CBEGH2_RS05270	COG1191	sigma factor activity
A9CBEGH2_RS05290	COG1827	regulation of RNA biosynthetic process
A9CBEGH2_RS05310	COG1876	peptidase activity
A9CBEGH2_RS05320	COG2197	response regulator
A9CBEGH2_RS05325	COG0322	excinuclease ABC activity
A9CBEGH2_RS05340	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A9CBEGH2_RS05360	COG0564	pseudouridine synthase activity
A9CBEGH2_RS05365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A9CBEGH2_RS05395	COG2801	Transposase and inactivated derivatives
A9CBEGH2_RS05400	COG0789	Transcriptional regulator
A9CBEGH2_RS05425	COG0756	dUTP diphosphatase activity
A9CBEGH2_RS05450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A9CBEGH2_RS05460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9CBEGH2_RS05470	COG0475	glutathione-regulated potassium exporter activity
A9CBEGH2_RS05475	COG0519	Catalyzes the synthesis of GMP from XMP
A9CBEGH2_RS05495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9CBEGH2_RS05500	COG0505	Belongs to the CarA family
A9CBEGH2_RS05505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A9CBEGH2_RS05515	COG0167	dihydroorotate dehydrogenase activity
A9CBEGH2_RS05520	COG0543	2 iron, 2 sulfur cluster binding
A9CBEGH2_RS05525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A9CBEGH2_RS05530	COG0540	Belongs to the ATCase OTCase family
A9CBEGH2_RS05560	COG0726	polysaccharide deacetylase
A9CBEGH2_RS05575	COG1461	Dihydroxyacetone kinase
A9CBEGH2_RS05580	COG1302	Protein conserved in bacteria
A9CBEGH2_RS05590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A9CBEGH2_RS05595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A9CBEGH2_RS05600	COG0772	Belongs to the SEDS family
A9CBEGH2_RS05605	COG4509	Sortase family
A9CBEGH2_RS05610	COG0640	Transcriptional regulator
A9CBEGH2_RS05615	COG5658	integral membrane protein
A9CBEGH2_RS05620	COG1131	(ABC) transporter
A9CBEGH2_RS05650	COG1132	(ABC) transporter
A9CBEGH2_RS05680	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A9CBEGH2_RS05685	COG1349	DNA-binding transcription factor activity
A9CBEGH2_RS05695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9CBEGH2_RS05715	COG1131	(ABC) transporter
A9CBEGH2_RS05720	COG1725	Transcriptional regulator
A9CBEGH2_RS05730	COG1215	transferase activity, transferring glycosyl groups
A9CBEGH2_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
A9CBEGH2_RS05755	COG1454	alcohol dehydrogenase
A9CBEGH2_RS05790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9CBEGH2_RS05795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9CBEGH2_RS05810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9CBEGH2_RS05815	COG0849	cell division
A9CBEGH2_RS05825	COG5263	repeat protein
A9CBEGH2_RS05825	COG4193	domain, Protein
A9CBEGH2_RS05830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A9CBEGH2_RS05845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9CBEGH2_RS05850	COG1162	GTPase activity
A9CBEGH2_RS05855	COG0515	serine threonine protein kinase
A9CBEGH2_RS05855	COG2815	serine threonine protein kinase
A9CBEGH2_RS05860	COG0631	protein serine/threonine phosphatase activity
A9CBEGH2_RS05865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A9CBEGH2_RS05870	COG0312	modulator of DNA gyrase
A9CBEGH2_RS05875	COG0312	modulator of DNA gyrase
A9CBEGH2_RS05890	COG2378	regulation of single-species biofilm formation
A9CBEGH2_RS05915	COG1408	metallophosphoesterase
A9CBEGH2_RS05920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9CBEGH2_RS05920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9CBEGH2_RS05930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A9CBEGH2_RS05985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9CBEGH2_RS05990	COG1328	CTP reductase activity
A9CBEGH2_RS05990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9CBEGH2_RS06005	COG0569	domain protein
A9CBEGH2_RS06010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9CBEGH2_RS06015	COG1592	Rubrerythrin
A9CBEGH2_RS06025	COG1283	sodium-dependent phosphate transmembrane transporter activity
A9CBEGH2_RS06030	COG0628	permease
A9CBEGH2_RS06040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9CBEGH2_RS06050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9CBEGH2_RS06075	COG0670	Belongs to the BI1 family
A9CBEGH2_RS06085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A9CBEGH2_RS06110	COG0442	prolyl-tRNA aminoacylation
A9CBEGH2_RS06130	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9CBEGH2_RS06130	COG2247	cell wall binding repeat
A9CBEGH2_RS06135	COG1013	pyruvate-flavodoxin oxidoreductase activity
A9CBEGH2_RS06135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A9CBEGH2_RS06135	COG0674	pyruvate-flavodoxin oxidoreductase activity
A9CBEGH2_RS06135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9CBEGH2_RS06175	COG0513	Belongs to the DEAD box helicase family
A9CBEGH2_RS06180	COG0561	phosphatase activity
A9CBEGH2_RS06185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9CBEGH2_RS06190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A9CBEGH2_RS06190	COG2080	2 iron, 2 sulfur cluster binding
A9CBEGH2_RS06240	COG2001	Belongs to the MraZ family
A9CBEGH2_RS06255	COG2176	DNA-directed DNA polymerase activity
A9CBEGH2_RS06270	COG2832	Protein of unknown function (DUF454)
A9CBEGH2_RS06280	COG1132	(ABC) transporter
A9CBEGH2_RS06285	COG4988	ABC transporter
A9CBEGH2_RS06320	COG1454	alcohol dehydrogenase
A9CBEGH2_RS06325	COG0719	Fe-S assembly protein
A9CBEGH2_RS06330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A9CBEGH2_RS06335	COG2848	UPF0210 protein
A9CBEGH2_RS06365	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS06370	COG1263	PTS System
A9CBEGH2_RS06370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS06370	COG2190	(PTS) system
A9CBEGH2_RS06375	COG3711	transcriptional antiterminator
A9CBEGH2_RS06380	COG3958	Transketolase
A9CBEGH2_RS06385	COG3959	Transketolase, thiamine diphosphate binding domain
A9CBEGH2_RS06390	COG2183	response to ionizing radiation
A9CBEGH2_RS06405	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9CBEGH2_RS06415	COG0613	PHP domain protein
A9CBEGH2_RS06465	COG0655	NAD(P)H dehydrogenase (quinone) activity
A9CBEGH2_RS06470	COG1105	Belongs to the carbohydrate kinase PfkB family
A9CBEGH2_RS06475	COG0561	phosphatase activity
A9CBEGH2_RS06480	COG1482	cell wall glycoprotein biosynthetic process
A9CBEGH2_RS06485	COG0561	phosphatase activity
A9CBEGH2_RS06500	COG2188	Transcriptional regulator
A9CBEGH2_RS06530	COG3328	transposase activity
A9CBEGH2_RS06540	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A9CBEGH2_RS06560	COG1482	cell wall glycoprotein biosynthetic process
A9CBEGH2_RS06580	COG3716	PTS system mannose fructose sorbose family IID component
A9CBEGH2_RS06590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS06590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS06610	COG0006	proline dipeptidase activity
A9CBEGH2_RS06630	COG2244	polysaccharide biosynthetic process
A9CBEGH2_RS06685	COG1640	4-alpha-glucanotransferase
A9CBEGH2_RS06705	COG4152	abc transporter atp-binding protein
A9CBEGH2_RS06715	COG1131	(ABC) transporter
A9CBEGH2_RS06720	COG2188	Transcriptional regulator
A9CBEGH2_RS06735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9CBEGH2_RS06740	COG1882	Formate acetyltransferase
A9CBEGH2_RS06750	COG1253	flavin adenine dinucleotide binding
A9CBEGH2_RS06755	COG0561	phosphatase activity
A9CBEGH2_RS06810	COG0583	DNA-binding transcription factor activity
A9CBEGH2_RS06840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9CBEGH2_RS06845	COG1295	ribonuclease BN
A9CBEGH2_RS06885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9CBEGH2_RS06890	COG0426	domain, Protein
A9CBEGH2_RS06895	COG1408	metallophosphoesterase
A9CBEGH2_RS06905	COG0393	Putative heavy-metal-binding
A9CBEGH2_RS06915	COG1780	Probably involved in ribonucleotide reductase function
A9CBEGH2_RS06920	COG0459	protein refolding
A9CBEGH2_RS06935	COG0569	domain protein
A9CBEGH2_RS06950	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS06955	COG2205	protein histidine kinase activity
A9CBEGH2_RS06960	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS06965	COG2205	protein histidine kinase activity
A9CBEGH2_RS06970	COG2205	protein histidine kinase activity
A9CBEGH2_RS06980	COG1131	(ABC) transporter
A9CBEGH2_RS06990	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A9CBEGH2_RS06995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A9CBEGH2_RS07000	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A9CBEGH2_RS07015	COG1476	TRANSCRIPTIONal
A9CBEGH2_RS07020	COG0343	queuine tRNA-ribosyltransferase activity
A9CBEGH2_RS07055	COG0366	Alpha amylase catalytic
A9CBEGH2_RS07060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS07060	COG1263	PTS System
A9CBEGH2_RS07065	COG2188	Transcriptional regulator
A9CBEGH2_RS07075	COG1528	Iron-storage protein
A9CBEGH2_RS07080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A9CBEGH2_RS07085	COG1028	Short-chain dehydrogenase reductase Sdr
A9CBEGH2_RS07090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A9CBEGH2_RS07120	COG1994	Peptidase M50
A9CBEGH2_RS07125	COG0535	radical SAM domain protein
A9CBEGH2_RS07135	COG1131	(ABC) transporter
A9CBEGH2_RS07175	COG0582	viral genome integration into host DNA
A9CBEGH2_RS07185	COG0519	Catalyzes the synthesis of GMP from XMP
A9CBEGH2_RS07185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A9CBEGH2_RS07195	COG0436	Aminotransferase
A9CBEGH2_RS07220	COG0114	fumarate hydratase activity
A9CBEGH2_RS07235	COG3191	aminopeptidase activity
A9CBEGH2_RS07245	COG0784	Response regulator, receiver
A9CBEGH2_RS07245	COG2205	protein histidine kinase activity
A9CBEGH2_RS07260	COG3437	response regulator, receiver
A9CBEGH2_RS07270	COG4608	Belongs to the ABC transporter superfamily
A9CBEGH2_RS07275	COG0444	Belongs to the ABC transporter superfamily
A9CBEGH2_RS07280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9CBEGH2_RS07285	COG0601	transmembrane transport
A9CBEGH2_RS07290	COG0747	negative chemotaxis
A9CBEGH2_RS07295	COG0205	6-phosphofructokinase activity
A9CBEGH2_RS07305	COG0697	spore germination
A9CBEGH2_RS07310	COG0488	(ABC) transporter
A9CBEGH2_RS07325	COG0017	Asparaginyl-tRNA synthetase
A9CBEGH2_RS07350	COG1136	(ABC) transporter
A9CBEGH2_RS07350	COG0577	efflux transmembrane transporter activity
A9CBEGH2_RS07355	COG1349	DNA-binding transcription factor activity
A9CBEGH2_RS07360	COG1363	Peptidase, m42
A9CBEGH2_RS07385	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A9CBEGH2_RS07410	COG0714	Associated with various cellular activities
A9CBEGH2_RS07420	COG0101	tRNA pseudouridine synthase activity
A9CBEGH2_RS07425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A9CBEGH2_RS07430	COG1122	ATPase activity
A9CBEGH2_RS07450	COG1115	amino acid carrier protein
A9CBEGH2_RS07455	COG2155	Conserved Protein
A9CBEGH2_RS07490	COG1794	racemase activity, acting on amino acids and derivatives
A9CBEGH2_RS07505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A9CBEGH2_RS07510	COG0557	exoribonuclease II activity
A9CBEGH2_RS07525	COG0148	phosphopyruvate hydratase activity
A9CBEGH2_RS07530	COG0647	UMP catabolic process
A9CBEGH2_RS07540	COG0250	Participates in transcription elongation, termination and antitermination
A9CBEGH2_RS07550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9CBEGH2_RS07560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9CBEGH2_RS07565	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A9CBEGH2_RS07570	COG0215	cysteine-tRNA ligase activity
A9CBEGH2_RS07580	COG0740	serine-type endopeptidase activity
A9CBEGH2_RS07600	COG3716	PTS system mannose fructose sorbose family IID component
A9CBEGH2_RS07605	COG3715	PTS system
A9CBEGH2_RS07610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS07620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS07620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS07625	COG2222	sugar isomerase
A9CBEGH2_RS07650	COG1481	regulation of sporulation
A9CBEGH2_RS07655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A9CBEGH2_RS07660	COG1660	Displays ATPase and GTPase activities
A9CBEGH2_RS07665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9CBEGH2_RS07675	COG2706	6-phosphogluconolactonase activity
A9CBEGH2_RS07685	COG1373	ATPase (AAA superfamily
A9CBEGH2_RS07700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A9CBEGH2_RS07730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9CBEGH2_RS07745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A9CBEGH2_RS07750	COG4149	molybdate abc transporter
A9CBEGH2_RS07755	COG0725	ABC transporter, periplasmic molybdate-binding protein
A9CBEGH2_RS07760	COG0521	Mo-molybdopterin cofactor biosynthetic process
A9CBEGH2_RS07780	COG1058	Belongs to the CinA family
A9CBEGH2_RS07780	COG1546	Belongs to the CinA family
A9CBEGH2_RS07785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A9CBEGH2_RS07785	COG3608	succinylglutamate desuccinylase aspartoacylase
A9CBEGH2_RS07795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9CBEGH2_RS07800	COG3608	succinylglutamate desuccinylase aspartoacylase
A9CBEGH2_RS07800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A9CBEGH2_RS07810	COG0709	Synthesizes selenophosphate from selenide and ATP
A9CBEGH2_RS07820	COG1876	peptidase activity
A9CBEGH2_RS07825	COG1114	Component of the transport system for branched-chain amino acids
A9CBEGH2_RS07830	COG0726	polysaccharide deacetylase
A9CBEGH2_RS07845	COG0297	glycogen (starch) synthase activity
A9CBEGH2_RS07860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A9CBEGH2_RS07870	COG0305	Participates in initiation and elongation during chromosome replication
A9CBEGH2_RS07875	COG0359	binds to the 23S rRNA
A9CBEGH2_RS07880	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A9CBEGH2_RS07890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A9CBEGH2_RS07895	COG0629	single-stranded DNA binding
A9CBEGH2_RS07900	COG0360	Binds together with S18 to 16S ribosomal RNA
A9CBEGH2_RS07910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9CBEGH2_RS07940	COG0583	DNA-binding transcription factor activity
A9CBEGH2_RS07950	COG1811	Na channel or pump
A9CBEGH2_RS07955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A9CBEGH2_RS08010	COG1511	domain protein
A9CBEGH2_RS08015	COG1959	2 iron, 2 sulfur cluster binding
A9CBEGH2_RS08020	COG0561	phosphatase activity
A9CBEGH2_RS08025	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS08035	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS08040	COG1486	melibiose metabolic process
A9CBEGH2_RS08045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS08050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS08055	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS08065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A9CBEGH2_RS08065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A9CBEGH2_RS08070	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS08075	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS08080	COG0406	alpha-ribazole phosphatase activity
A9CBEGH2_RS08090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS08090	COG2190	(PTS) system
A9CBEGH2_RS08090	COG1263	PTS System
A9CBEGH2_RS08095	COG0561	phosphatase activity
A9CBEGH2_RS08100	COG0561	phosphatase activity
A9CBEGH2_RS08115	COG3711	transcriptional antiterminator
A9CBEGH2_RS08120	COG0561	phosphatase activity
A9CBEGH2_RS08135	COG1940	carbohydrate kinase activity
A9CBEGH2_RS08145	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS08155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS08160	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS08165	COG2188	Transcriptional regulator
A9CBEGH2_RS08210	COG2197	response regulator
A9CBEGH2_RS08215	COG4585	Histidine kinase
A9CBEGH2_RS08220	COG1879	ABC-type sugar transport system periplasmic component
A9CBEGH2_RS08235	COG1362	aminopeptidase activity
A9CBEGH2_RS08280	COG0534	Mate efflux family protein
A9CBEGH2_RS08285	COG1846	Transcriptional regulator
A9CBEGH2_RS08290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9CBEGH2_RS08290	COG0723	plastoquinol--plastocyanin reductase activity
A9CBEGH2_RS08305	COG0402	S-adenosylhomocysteine deaminase activity
A9CBEGH2_RS08310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A9CBEGH2_RS08320	COG3842	ATPase activity
A9CBEGH2_RS08325	COG1177	transmembrane transport
A9CBEGH2_RS08330	COG1176	ABC-type spermidine putrescine transport system, permease component I
A9CBEGH2_RS08340	COG0826	peptidase U32
A9CBEGH2_RS08350	COG2966	Psort location CytoplasmicMembrane, score
A9CBEGH2_RS08370	COG2770	Histidine kinase
A9CBEGH2_RS08370	COG2205	protein histidine kinase activity
A9CBEGH2_RS08375	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS08380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9CBEGH2_RS08410	COG1214	PFAM Peptidase M22, glycoprotease
A9CBEGH2_RS08415	COG0802	atpase or kinase
A9CBEGH2_RS08435	COG3557	Belongs to the UPF0374 family
A9CBEGH2_RS08450	COG1956	GAF domain-containing protein
A9CBEGH2_RS08455	COG2746	aminoglycoside 3-N-acetyltransferase activity
A9CBEGH2_RS08485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A9CBEGH2_RS08500	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A9CBEGH2_RS08510	COG1194	a g-specific adenine glycosylase
A9CBEGH2_RS08515	COG1454	alcohol dehydrogenase
A9CBEGH2_RS08530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9CBEGH2_RS08535	COG1882	Formate acetyltransferase
A9CBEGH2_RS08540	COG0534	Mate efflux family protein
A9CBEGH2_RS08550	COG0006	proline dipeptidase activity
A9CBEGH2_RS08560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A9CBEGH2_RS08605	COG0704	Plays a role in the regulation of phosphate uptake
A9CBEGH2_RS08610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9CBEGH2_RS08615	COG0581	inorganic phosphate transmembrane transporter activity
A9CBEGH2_RS08625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A9CBEGH2_RS08640	COG0698	ribose 5-phosphate isomerase
A9CBEGH2_RS08650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9CBEGH2_RS08655	COG1126	abc transporter atp-binding protein
A9CBEGH2_RS08660	COG0765	amino acid transport
A9CBEGH2_RS08665	COG0009	L-threonylcarbamoyladenylate synthase
A9CBEGH2_RS08675	COG1393	Belongs to the ArsC family
A9CBEGH2_RS08685	COG0084	hydrolase, TatD family'
A9CBEGH2_RS08690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A9CBEGH2_RS08695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9CBEGH2_RS08705	COG0037	tRNA processing
A9CBEGH2_RS08715	COG0534	Mate efflux family protein
A9CBEGH2_RS08725	COG4166	transmembrane transport
A9CBEGH2_RS08730	COG0601	transmembrane transport
A9CBEGH2_RS08735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9CBEGH2_RS08740	COG0444	Belongs to the ABC transporter superfamily
A9CBEGH2_RS08745	COG4608	Belongs to the ABC transporter superfamily
A9CBEGH2_RS08755	COG1078	dGTPase activity
A9CBEGH2_RS08760	COG0494	nUDIX hydrolase
A9CBEGH2_RS08765	COG0673	inositol 2-dehydrogenase activity
A9CBEGH2_RS08775	COG1854	S-ribosylhomocysteine lyase activity
A9CBEGH2_RS08785	COG0733	neurotransmitter:sodium symporter activity
A9CBEGH2_RS08790	COG1301	dicarboxylic acid transport
A9CBEGH2_RS08805	COG1475	DNA binding
A9CBEGH2_RS08810	COG1192	Involved in chromosome partitioning
A9CBEGH2_RS08815	COG1475	DNA binding
A9CBEGH2_RS08845	COG0534	Mate efflux family protein
A9CBEGH2_RS08855	COG1074	ATP-dependent DNA helicase activity
A9CBEGH2_RS08870	COG2362	D-Aminopeptidase
A9CBEGH2_RS08885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A9CBEGH2_RS08895	COG1435	thymidine kinase activity
A9CBEGH2_RS08900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A9CBEGH2_RS08945	COG2211	Major facilitator Superfamily
A9CBEGH2_RS08955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A9CBEGH2_RS08955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9CBEGH2_RS08960	COG0534	Mate efflux family protein
A9CBEGH2_RS08985	COG3870	Protein conserved in bacteria
A9CBEGH2_RS08990	COG4667	esterase of the alpha-beta hydrolase superfamily
A9CBEGH2_RS09000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9CBEGH2_RS09015	COG2385	sporulation resulting in formation of a cellular spore
A9CBEGH2_RS09020	COG2207	Transcriptional regulator
A9CBEGH2_RS09020	COG4753	response regulator
A9CBEGH2_RS09025	COG2972	Histidine kinase
A9CBEGH2_RS09035	COG0641	radical SAM
A9CBEGH2_RS09050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A9CBEGH2_RS09055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A9CBEGH2_RS09065	COG0513	Belongs to the DEAD box helicase family
A9CBEGH2_RS09090	COG0151	Belongs to the GarS family
A9CBEGH2_RS09125	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A9CBEGH2_RS09175	COG3177	Filamentation induced by cAMP protein fic
A9CBEGH2_RS09215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9CBEGH2_RS09220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9CBEGH2_RS09225	COG1116	anion transmembrane transporter activity
A9CBEGH2_RS09235	COG0583	DNA-binding transcription factor activity
A9CBEGH2_RS09250	COG4607	ABC-type enterochelin transport system periplasmic component
A9CBEGH2_RS09255	COG4604	ABC transporter, ATP-binding protein
A9CBEGH2_RS09260	COG4605	iron ion homeostasis
A9CBEGH2_RS09265	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9CBEGH2_RS09270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A9CBEGH2_RS09290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9CBEGH2_RS09315	COG2203	Gaf domain
A9CBEGH2_RS09315	COG3706	GGDEF domain
A9CBEGH2_RS09315	COG5001	Diguanylate cyclase
A9CBEGH2_RS09315	COG4251	negative regulation of phosphorylation
A9CBEGH2_RS09320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9CBEGH2_RS09335	COG1773	rubredoxin
A9CBEGH2_RS09335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A9CBEGH2_RS09340	COG4716	Myosin-crossreactive antigen
A9CBEGH2_RS09360	COG0531	amino acid
A9CBEGH2_RS09365	COG1940	carbohydrate kinase activity
A9CBEGH2_RS09390	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9CBEGH2_RS09405	COG0667	Aldo Keto reductase
A9CBEGH2_RS09415	COG0534	Mate efflux family protein
A9CBEGH2_RS09420	COG0534	Mate efflux family protein
A9CBEGH2_RS09455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A9CBEGH2_RS09460	COG0577	efflux transmembrane transporter activity
A9CBEGH2_RS09465	COG1136	(ABC) transporter
A9CBEGH2_RS09470	COG2205	protein histidine kinase activity
A9CBEGH2_RS09475	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS09490	COG2252	PERMEase
A9CBEGH2_RS09500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A9CBEGH2_RS09505	COG0789	Transcriptional regulator
A9CBEGH2_RS09535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9CBEGH2_RS09540	COG0193	aminoacyl-tRNA hydrolase activity
A9CBEGH2_RS09545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9CBEGH2_RS09575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9CBEGH2_RS09575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9CBEGH2_RS09585	COG2946	Replication initiation factor
A9CBEGH2_RS09610	COG0768	penicillin binding
A9CBEGH2_RS09615	COG0463	Glycosyl transferase, family 2
A9CBEGH2_RS09635	COG0280	phosphate acetyltransferase
A9CBEGH2_RS09640	COG0280	phosphate acetyltransferase
A9CBEGH2_RS09650	COG0138	bifunctional purine biosynthesis protein purh
A9CBEGH2_RS09660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A9CBEGH2_RS09665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9CBEGH2_RS09670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A9CBEGH2_RS09685	COG1597	lipid kinase activity
A9CBEGH2_RS09690	COG1307	EDD domain protein, DegV family
A9CBEGH2_RS09695	COG0363	glucosamine-6-phosphate deaminase activity
A9CBEGH2_RS09705	COG0561	phosphatase activity
A9CBEGH2_RS09710	COG3716	PTS system mannose fructose sorbose family IID component
A9CBEGH2_RS09715	COG3715	PTS system
A9CBEGH2_RS09720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS09725	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A9CBEGH2_RS09725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A9CBEGH2_RS09730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS09735	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A9CBEGH2_RS09740	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9CBEGH2_RS09745	COG1774	PSP1 C-terminal conserved region
A9CBEGH2_RS09750	COG0470	DNA polymerase III
A9CBEGH2_RS09755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A9CBEGH2_RS09765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A9CBEGH2_RS09775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A9CBEGH2_RS09795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9CBEGH2_RS09800	COG0772	Belongs to the SEDS family
A9CBEGH2_RS09810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS09810	COG3711	transcriptional antiterminator
A9CBEGH2_RS09815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS09815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS09820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS09825	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS09830	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS09850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A9CBEGH2_RS09860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9CBEGH2_RS09865	COG0590	tRNA wobble adenosine to inosine editing
A9CBEGH2_RS09875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A9CBEGH2_RS09880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9CBEGH2_RS09885	COG0187	DNA topoisomerase II activity
A9CBEGH2_RS09890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A9CBEGH2_RS09895	COG2501	S4 domain
A9CBEGH2_RS09900	COG0592	DNA-directed DNA polymerase activity
A9CBEGH2_RS09905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A9CBEGH2_RS09925	COG1847	R3H domain protein
A9CBEGH2_RS09940	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS09950	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS09970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS09980	COG2971	BadF BadG BcrA BcrD
A9CBEGH2_RS09985	COG1737	Transcriptional regulator
A9CBEGH2_RS09990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A9CBEGH2_RS09995	COG0534	Mate efflux family protein
A9CBEGH2_RS10025	COG2171	N-acyltransferase activity
A9CBEGH2_RS10030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A9CBEGH2_RS10040	COG1473	amidohydrolase
A9CBEGH2_RS10050	COG5002	protein histidine kinase activity
A9CBEGH2_RS10055	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS10065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9CBEGH2_RS10070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9CBEGH2_RS10080	COG1129	ABC transporter
A9CBEGH2_RS10090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A9CBEGH2_RS10095	COG0285	dihydrofolate synthase activity
A9CBEGH2_RS10105	COG0456	acetyltransferase
A9CBEGH2_RS10120	COG1725	Transcriptional regulator
A9CBEGH2_RS10140	COG1131	(ABC) transporter
A9CBEGH2_RS10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9CBEGH2_RS10170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS10175	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS10195	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS10200	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS10210	COG3177	Filamentation induced by cAMP protein fic
A9CBEGH2_RS10215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9CBEGH2_RS10220	COG0366	Alpha amylase catalytic
A9CBEGH2_RS10225	COG0436	Aminotransferase
A9CBEGH2_RS10230	COG1522	sequence-specific DNA binding
A9CBEGH2_RS10240	COG2190	(PTS) system
A9CBEGH2_RS10250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS10250	COG1263	PTS System
A9CBEGH2_RS10250	COG2190	(PTS) system
A9CBEGH2_RS10255	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS10265	COG1739	Uncharacterized protein family UPF0029
A9CBEGH2_RS10275	COG2226	methyltransferase
A9CBEGH2_RS10290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9CBEGH2_RS10295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A9CBEGH2_RS10305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9CBEGH2_RS10315	COG1132	(ABC) transporter
A9CBEGH2_RS10320	COG1132	(ABC) transporter
A9CBEGH2_RS10340	COG1120	ATPase activity
A9CBEGH2_RS10345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9CBEGH2_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9CBEGH2_RS10370	COG1979	alcohol dehydrogenase
A9CBEGH2_RS10410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9CBEGH2_RS10410	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
A9CBEGH2_RS10420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A9CBEGH2_RS10430	COG0534	Mate efflux family protein
A9CBEGH2_RS10435	COG1695	Transcriptional regulator
A9CBEGH2_RS10460	COG1882	Formate acetyltransferase
A9CBEGH2_RS10475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A9CBEGH2_RS10480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9CBEGH2_RS10485	COG1940	carbohydrate kinase activity
A9CBEGH2_RS10490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS10495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS10500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9CBEGH2_RS10510	COG0191	fructose-bisphosphate aldolase activity
A9CBEGH2_RS10515	COG0191	fructose-bisphosphate aldolase activity
A9CBEGH2_RS10520	COG4821	SIS domain
A9CBEGH2_RS10525	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS10530	COG5002	protein histidine kinase activity
A9CBEGH2_RS10530	COG0642	Histidine kinase
A9CBEGH2_RS10550	COG2002	toxin-antitoxin pair type II binding
A9CBEGH2_RS10555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A9CBEGH2_RS10565	COG2190	(PTS) system
A9CBEGH2_RS10565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9CBEGH2_RS10565	COG1263	PTS System
A9CBEGH2_RS10575	COG2723	6-phospho-beta-galactosidase activity
A9CBEGH2_RS10580	COG0561	phosphatase activity
A9CBEGH2_RS10600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A9CBEGH2_RS10605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A9CBEGH2_RS10620	COG0356	it plays a direct role in the translocation of protons across the membrane
A9CBEGH2_RS10630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A9CBEGH2_RS10635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A9CBEGH2_RS10640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A9CBEGH2_RS10645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A9CBEGH2_RS10650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A9CBEGH2_RS10680	COG1132	(ABC) transporter
A9CBEGH2_RS10700	COG0287	Prephenate dehydrogenase
A9CBEGH2_RS10705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A9CBEGH2_RS10710	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A9CBEGH2_RS10715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A9CBEGH2_RS10720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A9CBEGH2_RS10730	COG1605	Chorismate mutase
A9CBEGH2_RS10730	COG0077	Prephenate dehydratase
A9CBEGH2_RS10740	COG0681	Belongs to the peptidase S26 family
A9CBEGH2_RS10745	COG0428	transporter
A9CBEGH2_RS10755	COG1346	cytolysis
A9CBEGH2_RS10775	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS10780	COG5002	protein histidine kinase activity
A9CBEGH2_RS10785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9CBEGH2_RS10795	COG0577	efflux transmembrane transporter activity
A9CBEGH2_RS10800	COG1136	(ABC) transporter
A9CBEGH2_RS10825	COG0071	Belongs to the small heat shock protein (HSP20) family
A9CBEGH2_RS10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9CBEGH2_RS10870	COG0018	arginyl-trna synthetase
A9CBEGH2_RS10875	COG3343	RNA polymerase activity
A9CBEGH2_RS10895	COG0024	Methionine aminopeptidase
A9CBEGH2_RS10900	COG1490	D-aminoacyl-tRNA deacylase activity
A9CBEGH2_RS10910	COG4481	Protein conserved in bacteria
A9CBEGH2_RS10915	COG1959	2 iron, 2 sulfur cluster binding
A9CBEGH2_RS10925	COG0012	GTP binding
A9CBEGH2_RS10950	COG0659	secondary active sulfate transmembrane transporter activity
A9CBEGH2_RS10985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9CBEGH2_RS10990	COG0537	adenosine 5'-monophosphoramidase activity
A9CBEGH2_RS10995	COG1971	Probably functions as a manganese efflux pump
A9CBEGH2_RS11025	COG1674	ftsk spoiiie
A9CBEGH2_RS11045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A9CBEGH2_RS11050	COG0735	belongs to the Fur family
A9CBEGH2_RS11055	COG1592	Rubrerythrin
A9CBEGH2_RS11090	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A9CBEGH2_RS11115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9CBEGH2_RS11125	COG0438	transferase activity, transferring glycosyl groups
A9CBEGH2_RS11130	COG0438	transferase activity, transferring glycosyl groups
A9CBEGH2_RS11140	COG0438	transferase activity, transferring glycosyl groups
A9CBEGH2_RS11150	COG0686	Belongs to the AlaDH PNT family
A9CBEGH2_RS11175	COG1316	TRANSCRIPTIONal
A9CBEGH2_RS11180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9CBEGH2_RS11185	COG1316	TRANSCRIPTIONal
A9CBEGH2_RS11200	COG0489	protein tyrosine kinase activity
A9CBEGH2_RS11215	COG0438	transferase activity, transferring glycosyl groups
A9CBEGH2_RS11225	COG0535	radical SAM domain protein
A9CBEGH2_RS11265	COG1484	DNA-dependent DNA replication
A9CBEGH2_RS11270	COG4584	PFAM Integrase catalytic
A9CBEGH2_RS11355	COG3757	hydrolase, family 25
A9CBEGH2_RS11355	COG3409	Peptidoglycan-binding domain 1 protein
A9CBEGH2_RS11375	COG0426	domain, Protein
A9CBEGH2_RS11375	COG1773	rubredoxin
A9CBEGH2_RS11380	COG1960	acyl-CoA dehydrogenase activity
A9CBEGH2_RS11385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9CBEGH2_RS11390	COG0668	transmembrane transport
A9CBEGH2_RS11395	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A9CBEGH2_RS11405	COG1278	Cold shock
A9CBEGH2_RS11415	COG0653	protein targeting
A9CBEGH2_RS11425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9CBEGH2_RS11430	COG2884	Cell division ATP-binding protein ftsE
A9CBEGH2_RS11435	COG2177	Part of the ABC transporter FtsEX involved in
A9CBEGH2_RS11440	COG0739	heme binding
A9CBEGH2_RS11445	COG2884	Cell division ATP-binding protein ftsE
A9CBEGH2_RS11450	COG2177	Part of the ABC transporter FtsEX involved in
A9CBEGH2_RS11455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A9CBEGH2_RS11460	COG0081	regulation of translation
A9CBEGH2_RS11465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A9CBEGH2_RS11470	COG0222	ribosome binding
A9CBEGH2_RS11475	COG2813	Specifically methylates the guanine in position
A9CBEGH2_RS11480	COG0085	RNA polymerase activity
A9CBEGH2_RS11485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A9CBEGH2_RS11490	COG0561	phosphatase activity
A9CBEGH2_RS11495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A9CBEGH2_RS11500	COG0049	tRNA binding
A9CBEGH2_RS11515	COG0051	transcription antitermination factor activity, RNA binding
A9CBEGH2_RS11520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A9CBEGH2_RS11525	COG0088	Forms part of the polypeptide exit tunnel
A9CBEGH2_RS11530	COG0089	rRNA binding
A9CBEGH2_RS11535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A9CBEGH2_RS11540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A9CBEGH2_RS11550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A9CBEGH2_RS11565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A9CBEGH2_RS11570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A9CBEGH2_RS11575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A9CBEGH2_RS11580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A9CBEGH2_RS11585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A9CBEGH2_RS11590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A9CBEGH2_RS11600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A9CBEGH2_RS11605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A9CBEGH2_RS11610	COG0200	Binds to the 23S rRNA
A9CBEGH2_RS11615	COG0201	protein transport
A9CBEGH2_RS11620	COG0563	adenylate kinase activity
A9CBEGH2_RS11625	COG0024	Methionine aminopeptidase
A9CBEGH2_RS11640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9CBEGH2_RS11645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A9CBEGH2_RS11650	COG0202	RNA polymerase activity
A9CBEGH2_RS11655	COG0203	ribosomal protein L17
A9CBEGH2_RS11660	COG4122	O-methyltransferase activity
A9CBEGH2_RS11675	COG0523	cobalamin synthesis protein
A9CBEGH2_RS11695	COG1132	(ABC) transporter
A9CBEGH2_RS11700	COG1132	(ABC) transporter
A9CBEGH2_RS11730	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9CBEGH2_RS11745	COG3711	transcriptional antiterminator
A9CBEGH2_RS11745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9CBEGH2_RS11750	COG1363	Peptidase, m42
A9CBEGH2_RS11755	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9CBEGH2_RS11760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS11765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9CBEGH2_RS11770	COG0006	proline dipeptidase activity
A9CBEGH2_RS11775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9CBEGH2_RS11805	COG1177	transmembrane transport
A9CBEGH2_RS11815	COG2177	Part of the ABC transporter FtsEX involved in
A9CBEGH2_RS11835	COG1164	Oligoendopeptidase f
A9CBEGH2_RS11840	COG1363	Peptidase, m42
A9CBEGH2_RS11855	COG1011	Hydrolase
A9CBEGH2_RS11865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9CBEGH2_RS11870	COG1181	Belongs to the D-alanine--D-alanine ligase family
A9CBEGH2_RS11875	COG2207	Transcriptional regulator
A9CBEGH2_RS11880	COG5426	von Willebrand factor, type A
A9CBEGH2_RS11895	COG1175	transmembrane transport
A9CBEGH2_RS11900	COG0395	ABC-type sugar transport system, permease component
A9CBEGH2_RS11910	COG3842	ATPase activity
A9CBEGH2_RS11915	COG0248	Ppx GppA phosphatase
A9CBEGH2_RS11920	COG0745	RESPONSE REGULATOR receiver
A9CBEGH2_RS11940	COG3627	carbon phosphorus lyase activity
A9CBEGH2_RS11945	COG4107	phosphonate C-P lyase system protein PhnK
A9CBEGH2_RS11950	COG3454	Phosphonate metabolism
A9CBEGH2_RS11960	COG4778	phosphonate C-P lyase system protein PhnL
A9CBEGH2_RS11965	COG1796	DNA polymerase
A9CBEGH2_RS11965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9CBEGH2_RS11970	COG0483	inositol monophosphate 1-phosphatase activity
A9CBEGH2_RS11985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A9CBEGH2_RS11995	COG3639	organic phosphonate transmembrane transporter activity
A9CBEGH2_RS12050	COG0534	Mate efflux family protein
A9CBEGH2_RS12060	COG1164	Oligoendopeptidase f
A9CBEGH2_RS12065	COG0813	purine-nucleoside phosphorylase activity
A9CBEGH2_RS12070	COG1937	Protein conserved in bacteria
A9CBEGH2_RS12085	COG1316	TRANSCRIPTIONal
A9CBEGH2_RS12090	COG1316	TRANSCRIPTIONal
A9CBEGH2_RS12095	COG0210	DNA helicase
A9CBEGH2_RS12100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A9CBEGH2_RS12110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9CBEGH2_RS12115	COG0154	amidase activity
A9CBEGH2_RS12120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9CBEGH2_RS12145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9CBEGH2_RS12160	COG1131	(ABC) transporter
A9CBEGH2_RS12175	COG0516	GMP reductase activity
A9CBEGH2_RS12175	COG0517	IMP dehydrogenase activity
A9CBEGH2_RS12195	COG3275	phosphorelay sensor kinase activity
A9CBEGH2_RS12200	COG2207	Transcriptional regulator
A9CBEGH2_RS12200	COG4753	response regulator
A9CBEGH2_RS12205	COG0126	phosphoglycerate kinase activity
A9CBEGH2_RS12210	COG0149	triose-phosphate isomerase activity
A9CBEGH2_RS12225	COG1994	Peptidase M50
A9CBEGH2_RS12260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9CBEGH2_RS12260	COG1328	CTP reductase activity
A9CBEGH2_RS12275	COG3409	Peptidoglycan-binding domain 1 protein
A9CBEGH2_RS12275	COG0793	Belongs to the peptidase S41A family
A9CBEGH2_RS12280	COG0556	nucleotide-excision repair
A9CBEGH2_RS12285	COG0628	permease
A9CBEGH2_RS12290	COG3022	response to hydroperoxide
A9CBEGH2_RS12295	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A9CBEGH2_RS12310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate