locus-tag class description Ami103574_RS00005 ENOG4108IQI permease Ami103574_RS00015 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Ami103574_RS00020 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami103574_RS00035 ENOG4105DJ2 Major Facilitator Superfamily Ami103574_RS00115 ENOG4105CDU Replicative dna helicase Ami103574_RS00140 ENOG4107T65 Integrase Ami103574_RS00160 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family Ami103574_RS00165 ENOG4105CJ1 ABC, transporter Ami103574_RS00175 ENOG4105CYW agmatinase Ami103574_RS00180 ENOG4108IQI permease Ami103574_RS00185 ENOG4108JUB Transcriptional regulator Ami103574_RS00245 ENOG4105HIR S-layer domain protein Ami103574_RS00250 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit Ami103574_RS00255 ENOG4105DGN Electron transport complex Ami103574_RS00260 ENOG4105DZB Electron transport complex Ami103574_RS00265 ENOG4108UQQ Electron transport complex Ami103574_RS00270 ENOG4105D6A Electron transport complex Ami103574_RS00275 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami103574_RS00280 ENOG4105CMU LysR family (Transcriptional regulator Ami103574_RS00290 ENOG4105KBH arsR family transcriptional regulator Ami103574_RS00295 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) Ami103574_RS00335 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) Ami103574_RS00345 ENOG4105DJZ UPF0182 protein Ami103574_RS00385 ENOG4108JUB Transcriptional regulator Ami103574_RS00390 ENOG4105CKM Branched-chain carboxylic acid kinase Ami103574_RS00395 ENOG4107RE7 phosphate butyryltransferase Ami103574_RS00400 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami103574_RS00405 ENOG4107QP7 CoA-transferase subunit A Ami103574_RS00415 ENOG4105CY2 Citrate transporter Ami103574_RS00420 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami103574_RS00425 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS00430 ENOG4105VTR Integrase Ami103574_RS00435 ENOG4105C2C drug resistance transporter, Bcr CflA Ami103574_RS00440 ENOG4105DRP amino acid AbC transporter Ami103574_RS00445 ENOG4105EAB amino acid AbC transporter Ami103574_RS00450 ENOG4105C28 cystathionine Ami103574_RS00455 ENOG4105CDA abc transporter atp-binding protein Ami103574_RS00465 ENOG4105CYW agmatinase Ami103574_RS00470 ENOG4108Z5V transcriptional regulator, merr family Ami103574_RS00475 ENOG4108UQV Membrane Ami103574_RS00480 ENOG4105C5R Aminotransferase Ami103574_RS00490 ENOG4105DZW Dipeptidase Ami103574_RS00515 ENOG4105VCQ rubredoxin Ami103574_RS00520 ENOG4105CNW domain protein Ami103574_RS00525 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) Ami103574_RS00540 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS00545 ENOG41082IR Excinuclease ABC C subunit domain protein Ami103574_RS00550 ENOG4107R88 Chemotaxis protein (CheV) Ami103574_RS00555 ENOG4106M28 alanine racemase domain protein Ami103574_RS00565 ENOG4105EQ5 D-Lysine 5,6-aminomutase alpha subunit Ami103574_RS00570 ENOG4105KIJ D-ornithine aminomutase S component Ami103574_RS00575 ENOG4107RH1 pyridoxal-5'-phosphate-dependent protein beta subunit Ami103574_RS00580 ENOG4105Z5Q Ami103574_RS00585 ENOG4108KR4 dihydrodipicolinate reductase Ami103574_RS00590 ENOG4108JUB Transcriptional regulator Ami103574_RS00615 ENOG4105BZU Histidine kinase Ami103574_RS00630 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) Ami103574_RS00655 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) Ami103574_RS00670 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase Ami103574_RS00690 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family Ami103574_RS00700 ENOG4107RBB ABC transporter, permease Ami103574_RS00705 ENOG4105C19 ABC transporter Ami103574_RS00710 ENOG410624X efflux transporter, rnd family, mfp subunit Ami103574_RS00720 ENOG4105FA0 parb-like partition protein Ami103574_RS00725 ENOG4107QJE Chromosome Partitioning Protein Ami103574_RS00735 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) Ami103574_RS00740 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami103574_RS00745 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) Ami103574_RS00750 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein Ami103574_RS00755 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins Ami103574_RS00760 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) Ami103574_RS00770 ENOG4105VG0 50S ribosomal protein l34 Ami103574_RS00780 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) Ami103574_RS00790 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Ami103574_RS00795 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Ami103574_RS00810 ENOG4105C31 Tryptophanyl-tRNA synthetase Ami103574_RS00825 ENOG410841Q phosphoesterase PA-phosphatase related protein Ami103574_RS00830 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) Ami103574_RS00835 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS00845 ENOG4105CHU acetyl-coa acetyltransferase Ami103574_RS00850 ENOG4107QW4 alcohol dehydrogenase Ami103574_RS00870 ENOG4108JUB Transcriptional regulator Ami103574_RS00880 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami103574_RS00895 ENOG4107RSM transcriptional regulator Ami103574_RS00900 ENOG4105FCD Major Facilitator Ami103574_RS00930 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) Ami103574_RS00935 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) Ami103574_RS00940 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) Ami103574_RS00950 ENOG4105C08 Histidine kinase Ami103574_RS00955 ENOG4105EEX Two component transcriptional regulator (Winged helix family Ami103574_RS00985 ENOG4105D7T ABC transporter Ami103574_RS01010 ENOG4105JQZ Methyltransferase Ami103574_RS01015 ENOG4105C28 cystathionine Ami103574_RS01025 ENOG4108NEV two component transcriptional regulator, LytTR family Ami103574_RS01060 ENOG4108V06 Glutathione peroxidase Ami103574_RS01065 ENOG4105K56 Transcriptional regulator Ami103574_RS01085 ENOG4108RVA ribokinase Ami103574_RS01095 ENOG4108UUM single-stranded DNA-binding protein Ami103574_RS01100 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) Ami103574_RS01115 ENOG4105C9X ppx gppa phosphatase Ami103574_RS01120 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS01125 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS01130 ENOG4105VTR Integrase Ami103574_RS01140 ENOG4105BZR domain protein Ami103574_RS01145 ENOG4105K9Q Binds to the 23S rRNA (By similarity) Ami103574_RS01150 ENOG4105CDU Replicative dna helicase Ami103574_RS01160 ENOG4105DR5 peptidase Ami103574_RS01165 ENOG4105DBI uridine monophosphokinase Ami103574_RS01170 ENOG4105VCQ rubredoxin Ami103574_RS01175 ENOG4108RAC Rubrerythrin Ami103574_RS01195 ENOG4105E5N succinylglutamate desuccinylase aspartoacylase Ami103574_RS01205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component Ami103574_RS01215 ENOG4105C3U ABC transporter Ami103574_RS01220 ENOG4108JQ7 (ABC) transporter Ami103574_RS01225 ENOG4107QJQ Mate efflux family protein Ami103574_RS01245 ENOG410810Y Sulfite reductase Ami103574_RS01260 ENOG4105D06 uba thif-type nad fad binding protein Ami103574_RS01270 ENOG4105EQD regulatoR Ami103574_RS01275 ENOG4105C6T cysteine synthase Ami103574_RS01280 ENOG4105GVF (ABC) transporter Ami103574_RS01285 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component Ami103574_RS01295 ENOG4105C6N Formate acetyltransferase Ami103574_RS01300 ENOG4105F1A Pyruvate formate-lyase Ami103574_RS01305 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami103574_RS01310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS01315 ENOG4105BZU Histidine kinase Ami103574_RS01335 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) Ami103574_RS01370 ENOG4108Z66 YbaK ebsC protein Ami103574_RS01375 ENOG4105KME endoribonuclease L-psp Ami103574_RS01380 ENOG4107ZC0 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) Ami103574_RS01390 ENOG4105FF2 Type I DHQase Ami103574_RS01395 ENOG4105E2X shikimate dehydrogenase Ami103574_RS01400 ENOG4105CQC Prephenate dehydratase Ami103574_RS01405 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase Ami103574_RS01410 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase Ami103574_RS01415 ENOG4105D49 3-dehydroquinate synthase Ami103574_RS01425 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase Ami103574_RS01430 ENOG4105BZU Histidine kinase Ami103574_RS01440 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami103574_RS01445 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami103574_RS01450 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami103574_RS01455 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami103574_RS01460 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) Ami103574_RS01465 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) Ami103574_RS01470 ENOG4105C7K acetolactate synthase Ami103574_RS01475 ENOG4108ZP8 Acetolactate synthase small subunit Ami103574_RS01480 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase Ami103574_RS01485 ENOG4105C01 Dihydroxy-acid dehydratase Ami103574_RS01520 ENOG4105C7B Threonine dehydratase Ami103574_RS01525 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) Ami103574_RS01535 ENOG4105BZ1 (ABC) transporter Ami103574_RS01540 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component Ami103574_RS01545 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component Ami103574_RS01555 ENOG4108JQ7 (ABC) transporter Ami103574_RS01560 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein Ami103574_RS01565 ENOG4105C84 Histidine ammonia-lyase Ami103574_RS01575 ENOG4105CI2 imidazolone-5-propionate hydrolase Ami103574_RS01585 ENOG4105CCS Glutamate formiminotransferase Ami103574_RS01595 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) Ami103574_RS01615 ENOG4105C2W permease Ami103574_RS01640 ENOG4105CTD carboxy-peptidase Ami103574_RS01645 ENOG4108ITV Inner membrane protein yqcE Ami103574_RS01650 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) Ami103574_RS01655 ENOG4105C83 adenylosuccinate lyase Ami103574_RS01670 ENOG4105EMN RNA polymerase sigma factor Ami103574_RS01685 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS01750 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS01760 ENOG4108X0B nad(p)h dehydrogenase (quinone) Ami103574_RS01770 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami103574_RS01795 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase Ami103574_RS01800 ENOG4105CI2 imidazolone-5-propionate hydrolase Ami103574_RS01805 ENOG4108Z6B deaminase Ami103574_RS01815 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) Ami103574_RS01820 ENOG4105DRR Transcriptional regulator, GntR family Ami103574_RS01825 ENOG4105DD5 Flagellar motor switch protein Ami103574_RS01840 ENOG4108ZXQ stage ii sporulation protein r Ami103574_RS01845 ENOG4105C0H protease Ami103574_RS01855 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) Ami103574_RS01870 ENOG4105CN1 protease Ami103574_RS01915 ENOG4105T09 s-layer domain-containing protein Ami103574_RS01920 ENOG4105HIR S-layer domain protein Ami103574_RS01935 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) Ami103574_RS01940 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) Ami103574_RS01945 ENOG4105CJR Integral membrane protein (MviN Ami103574_RS01955 ENOG4108DMA Nad-dependent epimerase dehydratase Ami103574_RS01960 ENOG4107SJB teichoic acid biosynthesis Ami103574_RS01970 ENOG4105D3Q Sugar transferase Ami103574_RS01975 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family Ami103574_RS01980 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase Ami103574_RS02005 ENOG4108PQP glycosyl transferase group 1 Ami103574_RS02015 ENOG4105C1B dTDP-glucose 4-6-dehydratase Ami103574_RS02025 ENOG4105EY8 ABC transporter Ami103574_RS02035 ENOG4107QRS glycosyltransferase group 2 family protein Ami103574_RS02055 ENOG4108UW5 maltose o-acetyltransferase Ami103574_RS02065 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) Ami103574_RS02095 ENOG4105CMR udp-glucose 4-epimerase Ami103574_RS02130 ENOG4107QYV phosphohexose isomerase Ami103574_RS02135 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami103574_RS02140 ENOG4108RCF TRANSCRIPTIONal Ami103574_RS02145 ENOG4108KGH TRANSCRIPTIONal Ami103574_RS02150 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) Ami103574_RS02155 ENOG4105CBJ Metal-dependent enzyme Ami103574_RS02160 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) Ami103574_RS02175 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) Ami103574_RS02180 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) Ami103574_RS02185 ENOG4108YZG isomerase Ami103574_RS02200 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS02210 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS02220 ENOG4105BZU Histidine kinase Ami103574_RS02225 ENOG4108DWA Nad synthetase Ami103574_RS02230 ENOG4105EQI Metal Dependent Phosphohydrolase Ami103574_RS02235 ENOG4105C7H Helicase, RecD TraA family Ami103574_RS02240 ENOG4105MJ2 Competence protein Ami103574_RS02250 ENOG4105C8B TIGR00159 family Ami103574_RS02260 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) Ami103574_RS02265 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) Ami103574_RS02275 ENOG4108JUB Transcriptional regulator Ami103574_RS02280 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Ami103574_RS02300 ENOG4105CH2 amidohydrolase Ami103574_RS02305 ENOG4105C0X amino acid Ami103574_RS02325 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) Ami103574_RS02340 ENOG4107VMI polysaccharide deacetylase Ami103574_RS02345 ENOG4105D98 threonine synthase Ami103574_RS02350 ENOG4108Z5K methylglyoxal synthase Ami103574_RS02370 ENOG4108IMY Transcriptional regulator Ami103574_RS02385 ENOG4105MCT stage V sporulation protein S Ami103574_RS02460 ENOG4108UUM single-stranded DNA-binding protein Ami103574_RS02710 ENOG4105K4W Could be involved in septation (By similarity) Ami103574_RS02720 ENOG4106A3R peptidase Ami103574_RS02850 ENOG4105D6J arsenicaL-resistance protein Ami103574_RS02875 ENOG4105K4H Nlp p60 protein Ami103574_RS02920 ENOG4105EKQ RNA-directed DNA polymerase Ami103574_RS02960 ENOG4107RBI VanW family Ami103574_RS02965 ENOG4105CPF Cell wall formation (By similarity) Ami103574_RS02990 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) Ami103574_RS03035 ENOG4107VGF ig domain protein group 2 domain protein Ami103574_RS03040 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS03060 ENOG4105C5I Dehydrogenase Ami103574_RS03080 ENOG4108JQ1 Dehydrogenase Ami103574_RS03090 ENOG4105E3H phosphoglycerate mutase Ami103574_RS03095 ENOG4105DZ1 carboxypeptidase Ami103574_RS03105 ENOG41068XD UPF0473 protein Ami103574_RS03115 ENOG4108ZC9 flagellar basal-body rod protein flgc Ami103574_RS03125 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) Ami103574_RS03130 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) Ami103574_RS03165 ENOG4108JQA flagellar Ami103574_RS03175 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) Ami103574_RS03180 ENOG4105DD5 Flagellar motor switch protein Ami103574_RS03185 ENOG4107YTP response regulator receiver protein Ami103574_RS03195 ENOG4105CN7 Flagellar biosynthetic protein FliP Ami103574_RS03200 ENOG4105VS8 Flagellar biosynthetic protein fliq Ami103574_RS03205 ENOG4108TN6 type iii secretion Ami103574_RS03210 ENOG4105D00 flagellar biosynthetic protein flhB Ami103574_RS03235 ENOG4105E1Q flagellar hook-associated protein Ami103574_RS03250 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) Ami103574_RS03255 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) Ami103574_RS03270 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) Ami103574_RS03275 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) Ami103574_RS03280 ENOG4105BZU Histidine kinase Ami103574_RS03285 ENOG4105CBS Chea signal transduction histidine kinase Ami103574_RS03290 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) Ami103574_RS03295 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) Ami103574_RS03300 ENOG4105D7B Flagellar biosynthesis protein flha Ami103574_RS03305 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS03310 ENOG4105CGA flagellar basal-body rod protein FlgG Ami103574_RS03315 ENOG4105CGA flagellar basal-body rod protein FlgG Ami103574_RS03325 ENOG4107PHP CheC --inhibitor of MCP methylation Ami103574_RS03340 ENOG4107QJE Chromosome Partitioning Protein Ami103574_RS03345 ENOG4107RT6 flagellar hook-associated Ami103574_RS03360 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) Ami103574_RS03370 ENOG4108JQ9 ABC transporter Ami103574_RS03375 ENOG4105UIB (ABC) transporter Ami103574_RS03390 ENOG4107S0N DJ-1 family Ami103574_RS03395 ENOG4105DB7 PHP domain protein Ami103574_RS03405 ENOG4105WG9 Conserved Protein Ami103574_RS03410 ENOG4105C22 threonyL-tRNA synthetase Ami103574_RS03415 ENOG4105DD7 kinase (PfkB family Ami103574_RS03420 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) Ami103574_RS03430 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) Ami103574_RS03440 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity Ami103574_RS03445 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) Ami103574_RS03450 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) Ami103574_RS03455 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) Ami103574_RS03460 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) Ami103574_RS03465 ENOG41082SA 50s ribosomal protein l29 Ami103574_RS03470 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal Ami103574_RS03475 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) Ami103574_RS03480 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) Ami103574_RS03485 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits Ami103574_RS03490 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) Ami103574_RS03495 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) Ami103574_RS03505 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) Ami103574_RS03510 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) Ami103574_RS03515 ENOG4105VPB 50S ribosomal protein L30 Ami103574_RS03520 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) Ami103574_RS03525 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) Ami103574_RS03540 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) Ami103574_RS03545 ENOG41067V7 50S ribosomal protein L36 Ami103574_RS03555 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) Ami103574_RS03565 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) Ami103574_RS03570 ENOG4108ZT0 50S ribosomal protein l17 Ami103574_RS03575 ENOG4108JJB ABC transporter Ami103574_RS03580 ENOG4108JJB ABC transporter Ami103574_RS03585 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) Ami103574_RS03595 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) Ami103574_RS03610 ENOG4105E9Q Acyl-transferase Ami103574_RS03635 ENOG4105CK1 PTS System Ami103574_RS03645 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) Ami103574_RS03650 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein Ami103574_RS03655 ENOG4105BZ8 glutamate synthase Ami103574_RS03660 ENOG4105CY0 Metallo-Beta-Lactamase Ami103574_RS03665 ENOG4108Z3G 3H domain protein Ami103574_RS03670 ENOG4105CH2 amidohydrolase Ami103574_RS03680 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) Ami103574_RS03690 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) Ami103574_RS03705 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami103574_RS03715 ENOG4107Y7X LytTR Ami103574_RS03750 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation Ami103574_RS03755 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) Ami103574_RS03765 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) Ami103574_RS03770 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) Ami103574_RS03780 ENOG4108UGV hypoxanthine phosphoribosyltransferase Ami103574_RS03785 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami103574_RS03845 ENOG4105CZX twitching motility protein Ami103574_RS03850 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) Ami103574_RS03870 ENOG4105D58 Diguanylate phosphodiesterase Ami103574_RS03900 ENOG4108Z29 Flavodoxin Ami103574_RS03915 ENOG4105VYW UPF0251 protein Ami103574_RS03920 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS03925 ENOG4107QP7 CoA-transferase subunit A Ami103574_RS03935 ENOG4106TD9 Diguanylate cyclase Ami103574_RS03960 ENOG4105C8M UPF0272 protein Ami103574_RS03990 ENOG4105BZU Histidine kinase Ami103574_RS03995 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS04015 ENOG4105VRS hydrolase family 18 Ami103574_RS04020 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS04020 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS04025 ENOG4107QSA Oxaloacetate decarboxylase Ami103574_RS04030 ENOG4105C9U ATP-dependent DNA helicase RecQ Ami103574_RS04035 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 Ami103574_RS04040 ENOG4105CVG Homoserine O-transsuccinylase Ami103574_RS04055 ENOG4105C5H ABC transporter Ami103574_RS04060 ENOG4105BZ1 (ABC) transporter Ami103574_RS04065 ENOG4105BZ1 (ABC) transporter Ami103574_RS04080 ENOG4105DIN metallophosphoesterase Ami103574_RS04090 ENOG4105EMN RNA polymerase sigma factor Ami103574_RS04100 ENOG4105DA5 (ABC) transporter Ami103574_RS04145 ENOG4105KRQ Addiction module toxin, Txe YoeB family Ami103574_RS04240 ENOG4107Y5K Resolvase Ami103574_RS04290 ENOG4105MCT stage V sporulation protein S Ami103574_RS04295 ENOG4108M14 stage v sporulation protein t Ami103574_RS04415 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) Ami103574_RS04510 ENOG4107VGF ig domain protein group 2 domain protein Ami103574_RS04535 ENOG4105WEF catalase Ami103574_RS04605 ENOG41066EA baseplate J family protein Ami103574_RS04640 ENOG41063SB peptidase Ami103574_RS04660 ENOG4105CGK Exodeoxyribonuclease III Ami103574_RS04690 ENOG4105VMP Transcriptional regulator Ami103574_RS04710 ENOG41082UD thioesterase Superfamily protein Ami103574_RS04715 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) Ami103574_RS04720 ENOG4106P55 Transcriptional regulator Ami103574_RS04730 ENOG4105CEB Aspartate aminotransferase Ami103574_RS04745 ENOG4107R7I amino acid Ami103574_RS04760 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Ami103574_RS04770 ENOG4108V4B ThiJ pfpI Ami103574_RS04790 ENOG4105D5G Transposase Ami103574_RS04815 ENOG41060M0 Crispr-associated protein, cse4 family Ami103574_RS04830 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) Ami103574_RS04835 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) Ami103574_RS04865 ENOG4105BZU Histidine kinase Ami103574_RS04870 ENOG4105KVH Transcriptional regulator Ami103574_RS04885 ENOG4105DNP FAD linked oxidase domain protein Ami103574_RS04890 ENOG4108U05 Transcriptional regulator Ami103574_RS04900 ENOG4105EB2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) Ami103574_RS04905 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami103574_RS04910 ENOG4108KB2 LysR family Transcriptional regulator Ami103574_RS04915 ENOG4105CHU acetyl-coa acetyltransferase Ami103574_RS04930 ENOG4105FCD Major Facilitator Ami103574_RS04940 ENOG4105BZ8 glutamate synthase Ami103574_RS04950 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) Ami103574_RS04980 ENOG41061TZ Short-chain dehydrogenase reductase Sdr Ami103574_RS04995 ENOG4105DZR Type I site-specific deoxyribonuclease Ami103574_RS05015 ENOG4105VUF Transcriptional regulator Ami103574_RS05020 ENOG4105C0A alcohol dehydrogenase Ami103574_RS05040 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS05045 ENOG4105EB3 Histidine kinase Ami103574_RS05050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS05055 ENOG41067TZ transcriptional regulator, MarR family Ami103574_RS05070 ENOG4105DMQ Methyltransferase Ami103574_RS05075 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family Ami103574_RS05085 ENOG4105BZ1 (ABC) transporter Ami103574_RS05105 ENOG4108VX5 3-methyladenine DNA glycosylase Ami103574_RS05110 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes Ami103574_RS05115 ENOG4105EEQ Na H antiporter Ami103574_RS05125 ENOG41080UX Methyltransferase Ami103574_RS05135 ENOG4107U9B transcriptional regulator Ami103574_RS05140 ENOG4108UMN azlc family Ami103574_RS05145 ENOG4105KMT branched-chain amino acid Ami103574_RS05160 ENOG4105KVH Transcriptional regulator Ami103574_RS05165 ENOG4105CUB amino acid Ami103574_RS05185 ENOG4105E14 MotA TolQ exbB proton channel Ami103574_RS05190 ENOG4105ER2 Ompa motb domain protein Ami103574_RS05200 ENOG4105C85 amino acid Ami103574_RS05220 ENOG4105G9B Transcriptional regulator Ami103574_RS05245 ENOG4105DTC 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase Ami103574_RS05255 ENOG41067QW Transcriptional regulator Ami103574_RS05275 ENOG4105W1Y Transcriptional regulator Ami103574_RS05295 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component Ami103574_RS05300 ENOG4105D2X ABC transporter substrate-binding protein Ami103574_RS05305 ENOG4105FAA peptidase M23 Ami103574_RS05310 ENOG4105D7N magnesium and cobalt transport protein CorA Ami103574_RS05315 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) Ami103574_RS05355 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Ami103574_RS05360 ENOG4105F38 ABC transporter, permease Ami103574_RS05365 ENOG4105D38 putrescine abc transporter Ami103574_RS05370 ENOG4107RUE extracellular solute-binding protein family 1 Ami103574_RS05375 ENOG4108V2W Carbonate dehydratase Ami103574_RS05380 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component Ami103574_RS05390 ENOG4105D7T ABC transporter Ami103574_RS05395 ENOG4105F8V Hydrolase, tatD family Ami103574_RS05415 ENOG4105DY9 regulatoR Ami103574_RS05425 ENOG4108DMH HTH_ARAC Ami103574_RS05430 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) Ami103574_RS05450 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase Ami103574_RS05475 ENOG4105DSE periplasmic solute binding protein Ami103574_RS05480 ENOG4105DIK (ABC) transporter Ami103574_RS05485 ENOG4105FAV ABC, transporter Ami103574_RS05495 ENOG4105BZU Histidine kinase Ami103574_RS05500 ENOG4105BZU Histidine kinase Ami103574_RS05530 ENOG4108JUB Transcriptional regulator Ami103574_RS05545 ENOG4105BZ1 (ABC) transporter Ami103574_RS05550 ENOG4105BZ1 (ABC) transporter Ami103574_RS05570 ENOG4105C7Z Conserved Protein Ami103574_RS05575 ENOG4105C7Z Conserved Protein Ami103574_RS05590 ENOG4108KXV response regulator Ami103574_RS05595 ENOG4105HIR S-layer domain protein Ami103574_RS05625 ENOG4105KNY Microcompartments protein Ami103574_RS05630 ENOG4108WT6 Carbon dioxide concentrating mechanism protein Ami103574_RS05635 ENOG4105C0A alcohol dehydrogenase Ami103574_RS05640 ENOG4105C6N Formate acetyltransferase Ami103574_RS05645 ENOG4105F1A Pyruvate formate-lyase Ami103574_RS05650 ENOG4105M3W utilization protein Ami103574_RS05675 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami103574_RS05690 ENOG4105KNY Microcompartments protein Ami103574_RS05695 ENOG4105C0A alcohol dehydrogenase Ami103574_RS05700 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami103574_RS05705 ENOG4105KNY Microcompartments protein Ami103574_RS05745 ENOG4108KSA LysR family transcriptional regulator Ami103574_RS05770 ENOG4105MCT stage V sporulation protein S Ami103574_RS05780 ENOG4105C5H ABC transporter Ami103574_RS05785 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) Ami103574_RS05790 ENOG4105II7 pyrroline-5-carboxylate reductase Ami103574_RS05805 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami103574_RS05810 ENOG4106PMH Extracellular solute-binding protein family 3 Ami103574_RS05815 ENOG4105E5Q amino acid AbC transporter Ami103574_RS05820 ENOG4105CDA abc transporter atp-binding protein Ami103574_RS05830 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) Ami103574_RS05835 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) Ami103574_RS05840 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) Ami103574_RS05845 ENOG4105SYT Methylenetetrahydrofolate reductase Ami103574_RS05850 ENOG4105CKU formyltetrahydrofolate synthetase Ami103574_RS05855 ENOG410908R Methenyltetrahydrofolate cyclohydrolase Ami103574_RS05860 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) Ami103574_RS05865 ENOG4105D52 delta-aminolevulinic acid dehydratase Ami103574_RS05870 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase Ami103574_RS05880 ENOG4105C59 p-type ATPase Ami103574_RS05890 ENOG4107PPM cobalt chelatase Ami103574_RS05900 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) Ami103574_RS05910 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) Ami103574_RS05920 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) Ami103574_RS05945 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) Ami103574_RS05950 ENOG4108IND Tetr family transcriptional regulator Ami103574_RS05960 ENOG4105VZ8 Transcriptional regulator Ami103574_RS05980 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) Ami103574_RS05995 ENOG4108JUB Transcriptional regulator Ami103574_RS06005 ENOG4105BZJ Electron transfer flavoprotein Ami103574_RS06010 ENOG4105C10 Electron transfer flavoprotein Ami103574_RS06025 ENOG4108IG5 Transcriptional regulator Ami103574_RS06035 ENOG4105BZ1 (ABC) transporter Ami103574_RS06040 ENOG4105BZU Histidine kinase Ami103574_RS06055 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) Ami103574_RS06060 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase Ami103574_RS06065 ENOG4105CBD Diacylglycerol kinase Ami103574_RS06075 ENOG4105KEG ribosomal-protein-alanine acetyltransferase Ami103574_RS06080 ENOG4108ZJ4 polysaccharide deacetylase Ami103574_RS06090 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A Ami103574_RS06100 ENOG4108JIC nucleoside recognition domain protein Ami103574_RS06125 ENOG4108IQI permease Ami103574_RS06130 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) Ami103574_RS06135 ENOG4105EFZ amidohydrolase Ami103574_RS06155 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) Ami103574_RS06160 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) Ami103574_RS06165 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) Ami103574_RS06170 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) Ami103574_RS06175 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) Ami103574_RS06180 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) Ami103574_RS06185 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase Ami103574_RS06215 ENOG4105CHM Aminotransferase Ami103574_RS06235 ENOG4105NA0 Transcriptional regulator Ami103574_RS06260 ENOG4105CVA phosphate Ami103574_RS06265 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) Ami103574_RS06270 ENOG4105K4H Nlp p60 protein Ami103574_RS06275 ENOG4108Z4T Peptidase M50 Ami103574_RS06280 ENOG4105KVH Transcriptional regulator Ami103574_RS06285 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit Ami103574_RS06300 ENOG4105DIK (ABC) transporter Ami103574_RS06325 ENOG4107QP7 CoA-transferase subunit A Ami103574_RS06330 ENOG4105C6Z Gluconate Ami103574_RS06335 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami103574_RS06340 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami103574_RS06360 ENOG4105GZI Transcriptional regulator Ami103574_RS06400 ENOG4105CBX hi0933 family Ami103574_RS06405 ENOG4105DZ0 fad dependent oxidoreductase Ami103574_RS06425 ENOG4105CIN aminoacyl-histidine dipeptidase Ami103574_RS06440 ENOG4108MRH transcriptional regulatory protein Ami103574_RS06455 ENOG4105CE1 Ferrous iron transport protein b Ami103574_RS06480 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) Ami103574_RS06500 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) Ami103574_RS06520 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation Ami103574_RS06540 ENOG4105CU9 asparagine synthetase A Ami103574_RS06545 ENOG4105D07 Signal peptide peptidase, SppA Ami103574_RS06550 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) Ami103574_RS06570 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) Ami103574_RS06585 ENOG4105DFA alanine racemase domain protein Ami103574_RS06590 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) Ami103574_RS06600 ENOG4107VQS DivIVA family Ami103574_RS06605 ENOG4107TEJ This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) Ami103574_RS06610 ENOG4105C34 Pseudouridine synthase Ami103574_RS06615 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) Ami103574_RS06630 ENOG4105DSJ YicC domain protein Ami103574_RS06635 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) Ami103574_RS06650 ENOG4105CE9 30S ribosomal protein S2 Ami103574_RS06660 ENOG4105DHT Metal Dependent Phosphohydrolase Ami103574_RS06670 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) Ami103574_RS06675 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) Ami103574_RS06690 ENOG4105DZP Membrane-associated zinc metalloprotease Ami103574_RS06695 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) Ami103574_RS06710 ENOG4105DZS Phenylacetate-CoA ligase Ami103574_RS06720 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) Ami103574_RS06725 ENOG4105CHV Transcription elongation factor NusA Ami103574_RS06735 ENOG4105VHM ribosomal protein Ami103574_RS06740 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) Ami103574_RS06745 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) Ami103574_RS06750 ENOG4105SFS phosphoesterase RecJ domain protein Ami103574_RS06755 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) Ami103574_RS06760 ENOG4105DTN riboflavin biosynthesis protein ribF Ami103574_RS06770 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) Ami103574_RS06775 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) Ami103574_RS06780 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR Ami103574_RS06785 ENOG4105E0M Sulfatase Ami103574_RS06795 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS06800 ENOG4105BZU Histidine kinase Ami103574_RS06805 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS06815 ENOG4108HRK Histidine kinase Ami103574_RS06820 ENOG4105DY9 regulatoR Ami103574_RS06835 ENOG4105CYC Transferase Ami103574_RS06855 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS06895 ENOG4107Y3V -acetyltransferase Ami103574_RS06910 ENOG4105DA5 (ABC) transporter Ami103574_RS06935 ENOG4108JUB Transcriptional regulator Ami103574_RS06940 ENOG41085RW This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) Ami103574_RS06945 ENOG4108IQI permease Ami103574_RS06960 ENOG4105E39 Enoyl-CoA hydratase Ami103574_RS06975 ENOG4105M6F mutator MutT protein Ami103574_RS06985 ENOG4105BZU Histidine kinase Ami103574_RS06990 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS07005 ENOG4105KT7 mgtC SapB transporter Ami103574_RS07015 ENOG4105CDH Citrulline--aspartate ligase Ami103574_RS07030 ENOG4106M28 alanine racemase domain protein Ami103574_RS07035 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) Ami103574_RS07040 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami103574_RS07045 ENOG4105CIE May be required for sporulation (By similarity) Ami103574_RS07060 ENOG4105CSA Coproporphyrinogen iii oxidase Ami103574_RS07085 ENOG4105CI3 gtp-binding protein typa Ami103574_RS07090 ENOG4108WCX response regulator Ami103574_RS07125 ENOG4105D3Q Sugar transferase Ami103574_RS07130 ENOG4105CG5 Glycosyl transferase (Group 1 Ami103574_RS07170 ENOG4105CMR udp-glucose 4-epimerase Ami103574_RS07175 ENOG4107QYV phosphohexose isomerase Ami103574_RS07195 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) Ami103574_RS07200 ENOG4107RUE extracellular solute-binding protein family 1 Ami103574_RS07205 ENOG4105F38 ABC transporter, permease Ami103574_RS07210 ENOG4105D38 putrescine abc transporter Ami103574_RS07215 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Ami103574_RS07220 ENOG4108TFM Kinase, PfkB family Ami103574_RS07225 ENOG41065RQ ADP-ribosylation crystallin J1 Ami103574_RS07235 ENOG4105D64 Mechanosensitive ion channel Ami103574_RS07240 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) Ami103574_RS07245 ENOG4105D82 Glutamate dehydrogenase Ami103574_RS07250 ENOG4105CJW magnesium transporter Ami103574_RS07255 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) Ami103574_RS07260 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) Ami103574_RS07285 ENOG4108HHA Transketolase Ami103574_RS07290 ENOG4108IUS Transketolase Ami103574_RS07305 ENOG4105DDQ anthranilate synthase Ami103574_RS07310 ENOG4108I0Q anthranilate phosphoribosyltransferase Ami103574_RS07320 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase Ami103574_RS07325 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) Ami103574_RS07330 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) Ami103574_RS07345 ENOG4105CAK Cell division ATP-binding protein ftsE Ami103574_RS07350 ENOG4105CRP Part of the ABC transporter FtsEX involved in Ami103574_RS07355 ENOG4105DR5 peptidase Ami103574_RS07360 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) Ami103574_RS07380 ENOG4105C2F Histidine kinase Ami103574_RS07385 ENOG41075H3 AraC family transcriptional regulator Ami103574_RS07390 ENOG4105EHR propanediol utilization protein pduB Ami103574_RS07400 ENOG4105YCI dehydratase medium subunit Ami103574_RS07405 ENOG4108ZFT Dehydratase small subunit Ami103574_RS07410 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit Ami103574_RS07425 ENOG4105KNY Microcompartments protein Ami103574_RS07430 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami103574_RS07450 ENOG4108EKI Dehydrogenase Ami103574_RS07455 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami103574_RS07470 ENOG4105M3W utilization protein Ami103574_RS07475 ENOG4105KTW ethanolamine utilization protein Ami103574_RS07480 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) Ami103574_RS07485 ENOG4105KGF protein, YerC YecD Ami103574_RS07495 ENOG4105Y3E Modulates RecA activity (By similarity) Ami103574_RS07510 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) Ami103574_RS07525 ENOG4108TVT permease Ami103574_RS07530 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) Ami103574_RS07535 ENOG4105K4I Scp-like extracellular Ami103574_RS07540 ENOG4105DIH basic membrane Ami103574_RS07545 ENOG4108JQ9 ABC transporter Ami103574_RS07550 ENOG4105UIB (ABC) transporter Ami103574_RS07570 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) Ami103574_RS07575 ENOG4105BZ1 (ABC) transporter Ami103574_RS07580 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate Ami103574_RS07590 ENOG4108UB4 uncharacterized protein ygjQ Ami103574_RS07615 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) Ami103574_RS07635 ENOG4105ETT transcriptional Regulator, LysR family Ami103574_RS07660 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate Ami103574_RS07675 ENOG4105VPX protein, conserved in bacteria Ami103574_RS07690 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component Ami103574_RS07695 ENOG4105C3U ABC transporter Ami103574_RS07700 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) Ami103574_RS07705 ENOG4105D65 subunit l Ami103574_RS07715 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit Ami103574_RS07725 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) Ami103574_RS07740 ENOG4107RSS Hydrogenase accessory protein HypB Ami103574_RS07750 ENOG4105WRB Hydrogenase assembly chaperone hypC hupF Ami103574_RS07755 ENOG4105CQS hydrogenase expression formation protein HypD Ami103574_RS07760 ENOG4105C45 hydrogenase expression formation protein (HypE) Ami103574_RS07780 ENOG4107UIE peptidase Ami103574_RS07790 ENOG41090E6 transcriptional regulator MERR family Ami103574_RS07795 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) Ami103574_RS07800 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) Ami103574_RS07805 ENOG4105MAX Superoxide reductase Ami103574_RS07815 ENOG4107BJW polysaccharide deacetylase Ami103574_RS07845 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) Ami103574_RS07850 ENOG4107YU2 histidine triad (hIT) protein Ami103574_RS07855 ENOG4105VCC 30S ribosomal protein S21 Ami103574_RS07870 ENOG4105C6T cysteine synthase Ami103574_RS07885 ENOG4105C9A Phoh family Ami103574_RS07890 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) Ami103574_RS07895 ENOG4105KG3 cytidine deaminase Ami103574_RS07900 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) Ami103574_RS07910 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) Ami103574_RS07920 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) Ami103574_RS07935 ENOG4107RBI VanW family Ami103574_RS07940 ENOG4105CPF Cell wall formation (By similarity) Ami103574_RS07955 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit Ami103574_RS07970 ENOG4105DPZ Two component transcriptional regulator (Winged helix family Ami103574_RS07975 ENOG4105BZU Histidine kinase Ami103574_RS07980 ENOG4105CKD glutathione-regulated potassium-efflux system protein Ami103574_RS08025 ENOG4108JUB Transcriptional regulator Ami103574_RS08030 ENOG4105D2S major facilitator superfamily Ami103574_RS08035 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) Ami103574_RS08040 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami103574_RS08055 ENOG4105D1H recombination factor protein RarA Ami103574_RS08060 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) Ami103574_RS08065 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) Ami103574_RS08070 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) Ami103574_RS08075 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) Ami103574_RS08080 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) Ami103574_RS08095 ENOG4105JFG SpoIID LytB domain protein Ami103574_RS08105 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) Ami103574_RS08110 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) Ami103574_RS08160 ENOG4105C59 p-type ATPase Ami103574_RS08170 ENOG4106V2I dimethylaminohydrolase Ami103574_RS08185 ENOG4105C1J atp-dependent rna helicase Ami103574_RS08205 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) Ami103574_RS08210 ENOG4108594 Permease of the drug metabolite transporter Ami103574_RS08235 ENOG41086D8 Transcriptional regulator Ami103574_RS08250 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) Ami103574_RS08265 ENOG4105DR5 peptidase Ami103574_RS08270 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) Ami103574_RS08280 ENOG41083UI stage II sporulation protein Ami103574_RS08285 ENOG4107SGM protein serine threonine phosphatase Ami103574_RS08300 ENOG4108JJA ABC, transporter Ami103574_RS08310 ENOG4105W1Y Transcriptional regulator Ami103574_RS08315 ENOG4105KME endoribonuclease L-psp Ami103574_RS08330 ENOG4105EPD Oligopeptide transporter, Opt family Ami103574_RS08335 ENOG4105CIN aminoacyl-histidine dipeptidase Ami103574_RS08350 ENOG4107QN2 dihydrolipoyl dehydrogenase Ami103574_RS08360 ENOG4108NEV two component transcriptional regulator, LytTR family Ami103574_RS08370 ENOG410631K Membrane Ami103574_RS08375 ENOG4106AXJ AraC family transcriptional regulator Ami103574_RS08395 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b Ami103574_RS08400 ENOG4105EUB pirin domain protein Ami103574_RS08405 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) Ami103574_RS08425 ENOG4105GZI Transcriptional regulator Ami103574_RS08450 ENOG4105CEN a g-specific adenine glycosylase Ami103574_RS08455 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS08460 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS08475 ENOG4105VDT -acetyltransferase Ami103574_RS08480 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase Ami103574_RS08485 ENOG4105F1A Pyruvate formate-lyase Ami103574_RS08490 ENOG4105VB9 50S ribosomal protein l28 Ami103574_RS08515 ENOG4106H78 methyltransferase Ami103574_RS08535 ENOG4105CDE UPF0348 protein Ami103574_RS08540 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) Ami103574_RS08545 ENOG41067VY 50S ribosomal protein L32 Ami103574_RS08565 ENOG4107QK3 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11 Ami103574_RS08580 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) Ami103574_RS08585 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Ami103574_RS08595 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) Ami103574_RS08600 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) Ami103574_RS08605 ENOG4105K46 50S ribosomal protein l27 Ami103574_RS08625 ENOG4105CSA Coproporphyrinogen iii oxidase Ami103574_RS08635 ENOG4105KQC Competence protein Ami103574_RS08645 ENOG4105S1Z Stage IV sporulation protein B Ami103574_RS08650 ENOG4107QQR Sporulation Ami103574_RS08670 ENOG4107QI6 Cysteine desulfurase Ami103574_RS08675 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins Ami103574_RS08705 ENOG4105M7K Involved in the transcription termination process (By similarity) Ami103574_RS08710 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) Ami103574_RS08715 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) Ami103574_RS08725 ENOG4105CTB Polyprenyl synthetase Ami103574_RS08730 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) Ami103574_RS08735 ENOG4105DX0 Hemolysin A Ami103574_RS08740 ENOG4105CHM Aminotransferase Ami103574_RS08745 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) Ami103574_RS08750 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) Ami103574_RS08755 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) Ami103574_RS08760 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami103574_RS08765 ENOG4105CXI aluminum resistance protein Ami103574_RS08770 ENOG4108N5C SNARE associated Golgi protein-related protein Ami103574_RS08785 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen Ami103574_RS08855 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) Ami103574_RS08860 ENOG4105VBH UPF0297 protein Ami103574_RS08875 ENOG4105KQ4 Stage iii sporulation protein ad Ami103574_RS08890 ENOG4105CD2 stage iii sporulation protein aa Ami103574_RS08895 ENOG4105C37 (CBS) domain Ami103574_RS08900 ENOG4105CFP Peptidase U32 Ami103574_RS08910 ENOG4105HHA aminodeoxychorismate lyase Ami103574_RS08915 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) Ami103574_RS08920 ENOG41084CE UPF0342 protein Ami103574_RS08925 ENOG4105CN5 Metallo-Beta-Lactamase Ami103574_RS08940 ENOG4108WF2 Metal Dependent Phosphohydrolase Ami103574_RS08955 ENOG4105CUT histidyl-tRNA synthetase Ami103574_RS08960 ENOG4105D4P Coproporphyrinogen iii oxidase Ami103574_RS08965 ENOG4107VMB Beta-lactamase domain protein Ami103574_RS08970 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) Ami103574_RS08975 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) Ami103574_RS08980 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) Ami103574_RS08990 ENOG4105VIE preprotein translocase, subunit YajC Ami103574_RS09010 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) Ami103574_RS09015 ENOG4105C2M dna polymerase I Ami103574_RS09025 ENOG4105EMN RNA polymerase sigma factor Ami103574_RS09030 ENOG4107RU2 Histidinol phosphate phosphatase, HisJ family Ami103574_RS09035 ENOG4105C37 (CBS) domain Ami103574_RS09040 ENOG4108Z6Z Transcriptional regulator Ami103574_RS09045 ENOG4105CJ1 ABC, transporter Ami103574_RS09055 ENOG4105KAV tspo and mbr like protein Ami103574_RS09060 ENOG4108RS6 transposase Ami103574_RS09065 ENOG4105KXX peptidase s58 dmpa Ami103574_RS09085 ENOG4105CDY transcriptional regulatory protein Ami103574_RS09120 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS09125 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) Ami103574_RS09130 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein Ami103574_RS09135 ENOG4105CJ3 phosphate transporter Ami103574_RS09150 ENOG4105CH6 catalase Ami103574_RS09155 ENOG41081F0 Precorrin-8x methylmutase Ami103574_RS09165 ENOG4107QZB decarboxylase Ami103574_RS09175 ENOG4105E4R Precorrin-3B C17-methyltransferase Ami103574_RS09180 ENOG4105CIA precorrin-4 C(11)-methyltransferase Ami103574_RS09190 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) Ami103574_RS09195 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase Ami103574_RS09200 ENOG4108P62 biosynthesis protein (CbiG) Ami103574_RS09210 ENOG4105C1V Peptidase, M16 Ami103574_RS09230 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein Ami103574_RS09260 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) Ami103574_RS09270 ENOG4105CHH sulfate transporter Ami103574_RS09290 ENOG4105DZ6 Band 7 protein Ami103574_RS09300 ENOG4105FF5 Membrane Ami103574_RS09325 ENOG4105C87 Aminotransferase class I and II Ami103574_RS09350 ENOG4105DC7 peptidase M24 Ami103574_RS09365 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) Ami103574_RS09370 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS09375 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami103574_RS09380 ENOG4105EYH Exonuclease Ami103574_RS09385 ENOG4107RFY SbcCD D subunit Ami103574_RS09390 ENOG4105F32 YngK protein Ami103574_RS09395 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen Ami103574_RS09400 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase Ami103574_RS09415 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS09430 ENOG4108UIC UPF0340 protein Ami103574_RS09440 ENOG4108UT2 hemolysin iii Ami103574_RS09465 ENOG4105CJG carbon-monoxide dehydrogenase catalytic subunit Ami103574_RS09470 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) Ami103574_RS09475 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) Ami103574_RS09490 ENOG4108IQE Amp-dependent synthetase and ligase Ami103574_RS09495 ENOG4105D3A purine nucleoside phosphorylase DeoD-type Ami103574_RS09505 ENOG4105KNY Microcompartments protein Ami103574_RS09510 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami103574_RS09515 ENOG4105C0A alcohol dehydrogenase Ami103574_RS09525 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami103574_RS09530 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami103574_RS09535 ENOG4105CCI Myosin-Cross-Reactive Antigen Ami103574_RS09545 ENOG4105CFG Acts as a chaperone (By similarity) Ami103574_RS09550 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ Ami103574_RS09555 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) Ami103574_RS09560 ENOG4108IV0 ABC, transporter Ami103574_RS09565 ENOG4105C0Z ABC transporter Ami103574_RS09570 ENOG4105CF8 branched-chain amino acid ABC transporter, permease Ami103574_RS09575 ENOG4105C32 Amino acid ABC transporter (Permease) Ami103574_RS09580 ENOG4105CP9 extracellular ligand-binding receptor Ami103574_RS09595 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) Ami103574_RS09605 ENOG4105VMP Transcriptional regulator Ami103574_RS09620 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) Ami103574_RS09630 ENOG4105CSA Coproporphyrinogen iii oxidase Ami103574_RS09645 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) Ami103574_RS09660 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) Ami103574_RS09665 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) Ami103574_RS09670 ENOG4105W4W Transcriptional regulator Ami103574_RS09685 ENOG4105CEU Arginine dihydrolase Ami103574_RS09690 ENOG4107VHA regulatoR Ami103574_RS09695 ENOG4105D5Q Arginine ornithine antiporter Ami103574_RS09700 ENOG4105D6E homoserine dehydrogenase Ami103574_RS09705 ENOG4108K88 Membrane Ami103574_RS09710 ENOG4105FR1 rard protein Ami103574_RS09725 ENOG4105DPN Oligoendopeptidase f Ami103574_RS09730 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) Ami103574_RS09735 ENOG4105C34 Pseudouridine synthase Ami103574_RS09740 ENOG4105BZU Histidine kinase Ami103574_RS09745 ENOG4108UYE Lactoylglutathione lyase Ami103574_RS09785 ENOG4106WTF Glycosyl transferase, family 2 Ami103574_RS09850 ENOG4105H67 Protein of unknown function (DUF421) Ami103574_RS09860 ENOG4105X71 Membrane Ami103574_RS09865 ENOG41082I2 s4 domain protein Ami103574_RS09870 ENOG4107S9D Alpha beta hydrolase Ami103574_RS09875 ENOG4105K70 DNA-binding protein Ami103574_RS09880 ENOG4105DXN mazG family Ami103574_RS09890 ENOG41080U2 Amidohydrolase family Ami103574_RS09895 ENOG4108M14 stage v sporulation protein t Ami103574_RS09900 ENOG4108JA2 transcriptioN-repair coupling factor Ami103574_RS09905 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) Ami103574_RS09915 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) Ami103574_RS09920 ENOG4105DFU Cell wall formation (By similarity) Ami103574_RS09925 ENOG4105DFT pur operon repressor Ami103574_RS09930 ENOG4105K4W Could be involved in septation (By similarity) Ami103574_RS09935 ENOG4105C3M thioredoxin reductase Ami103574_RS09940 ENOG4105K63 Thioredoxin Ami103574_RS09955 ENOG4105E4C Lytic transglycosylase catalytic Ami103574_RS09960 ENOG4105C7N Xanthine uracil vitamin C permease Ami103574_RS09970 ENOG4105CJN penicillin-binding protein Ami103574_RS09985 ENOG4107T14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) Ami103574_RS09995 ENOG4105JVQ RNA Polymerase Ami103574_RS10000 ENOG4105D3R alkyl hydroperoxide reductase Ami103574_RS10015 ENOG4105D29 Helix-turn-helix type 11 domain protein Ami103574_RS10020 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) Ami103574_RS10025 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) Ami103574_RS10030 ENOG4105SKN orotidine 5''-phosphate decarboxylase Ami103574_RS10035 ENOG4105CD3 dihydroorotase Ami103574_RS10050 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Ami103574_RS10095 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family Ami103574_RS10100 ENOG4105DVE abc transporter atp-binding protein Ami103574_RS10110 ENOG4105CXN decarboxylase Ami103574_RS10115 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) Ami103574_RS10120 ENOG4105CBX hi0933 family Ami103574_RS10145 ENOG4105E0X reductase Ami103574_RS10155 ENOG4105DA5 (ABC) transporter Ami103574_RS10185 ENOG4105EB3 Histidine kinase Ami103574_RS10190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS10195 ENOG410681U heavy metal transport detoxification protein Ami103574_RS10205 ENOG4105C59 p-type ATPase Ami103574_RS10215 ENOG4105C59 p-type ATPase Ami103574_RS10230 ENOG4105BZU Histidine kinase Ami103574_RS10235 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS10260 ENOG4105K5X acetyltransferase Ami103574_RS10310 ENOG4105CWM branched-chain amino acid transport system II carrier protein Ami103574_RS10325 ENOG4105D17 glycoside hydrolase, family 3 domain protein Ami103574_RS10335 ENOG4107TXC Transcriptional regulator Ami103574_RS10370 ENOG4108IPW abc transporter atp-binding protein Ami103574_RS10375 ENOG4105CM4 permease protein Ami103574_RS10425 ENOG4108Y4K DNA-binding transcriptional activator Ami103574_RS10460 ENOG4105DDK oxidoreductase, beta subunit Ami103574_RS10465 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) Ami103574_RS10475 ENOG4105EJ5 oxidoreductase gamma subunit Ami103574_RS10495 ENOG4105PW4 Sugar fermentation stimulation protein homolog Ami103574_RS10500 ENOG4105DWF phosphomethylpyrimidine kinase Ami103574_RS10505 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 Ami103574_RS10510 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) Ami103574_RS10515 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase Ami103574_RS10520 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) Ami103574_RS10525 ENOG4105DZ1 carboxypeptidase Ami103574_RS10535 ENOG4105EEX Two component transcriptional regulator (Winged helix family Ami103574_RS10540 ENOG4105C08 Histidine kinase Ami103574_RS10560 ENOG4105C5H ABC transporter Ami103574_RS10560 ENOG4105C5H ABC transporter Ami103574_RS10565 ENOG4105CNW domain protein Ami103574_RS10570 ENOG4105C1G acyl-Coa dehydrogenase Ami103574_RS10585 ENOG4108IQI permease Ami103574_RS10595 ENOG4105BZU Histidine kinase Ami103574_RS10600 ENOG4108IQI permease Ami103574_RS10605 ENOG4105C26 Dehydrogenase Ami103574_RS10610 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Ami103574_RS10645 ENOG4105ZU5 s-layer protein Ami103574_RS10655 ENOG41067QW Transcriptional regulator Ami103574_RS10660 ENOG4108IMY Transcriptional regulator Ami103574_RS10675 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein Ami103574_RS10685 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) Ami103574_RS10745 ENOG4105W5Q DNA repair protein (RadC Ami103574_RS10905 ENOG4108UUM single-stranded DNA-binding protein Ami103574_RS10960 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin Ami103574_RS10970 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) Ami103574_RS10975 ENOG4108R6K riboflavin synthase, subunit alpha Ami103574_RS10980 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) Ami103574_RS10990 ENOG4105C6K Malic enzyme Ami103574_RS10995 ENOG4108IJ0 Aspartate ammonia-lyase Ami103574_RS11000 ENOG4105CMU LysR family (Transcriptional regulator Ami103574_RS11015 ENOG4107R7I amino acid Ami103574_RS11020 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) Ami103574_RS11030 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Ami103574_RS11040 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) Ami103574_RS11060 ENOG4105E39 Enoyl-CoA hydratase Ami103574_RS11080 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) Ami103574_RS11115 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Ami103574_RS11125 ENOG4107QIZ NADH dehydrogenase Ami103574_RS11130 ENOG4105GKE subunit e Ami103574_RS11145 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 Ami103574_RS11150 ENOG4105BZ4 penicillin-binding protein Ami103574_RS11155 ENOG4105DYB Isoaspartyl dipeptidase Ami103574_RS11160 ENOG4105CSX c4-dicarboxylate anaerobic carrier Ami103574_RS11165 ENOG4108JUB Transcriptional regulator Ami103574_RS11190 ENOG4105CZ3 stage V sporulation protein ad Ami103574_RS11195 ENOG41090VF Stage v sporulation protein ac Ami103574_RS11200 ENOG4108Z03 MAF-like protein Ami103574_RS11210 ENOG4105C6K Malic enzyme Ami103574_RS11215 ENOG4105C10 Electron transfer flavoprotein Ami103574_RS11220 ENOG4105BZJ Electron transfer flavoprotein Ami103574_RS11225 ENOG4105C1G acyl-Coa dehydrogenase Ami103574_RS11230 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS11240 ENOG41082AN stage II sporulation protein Ami103574_RS11245 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) Ami103574_RS11260 ENOG4105CNI cell division protein FtsW Ami103574_RS11270 ENOG4107RF6 penicillin-binding protein Ami103574_RS11285 ENOG4105DFF Rod shape-determining protein mreb Ami103574_RS11290 ENOG4105W5Q DNA repair protein (RadC Ami103574_RS11300 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS11305 ENOG4105BZU Histidine kinase Ami103574_RS11310 ENOG4105BZU Histidine kinase Ami103574_RS11320 ENOG4105CDA abc transporter atp-binding protein Ami103574_RS11325 ENOG4105DSP amino acid AbC transporter Ami103574_RS11330 ENOG4105E5Q amino acid AbC transporter Ami103574_RS11340 ENOG4105CAT Cytidine monophosphate kinase Ami103574_RS11345 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) Ami103574_RS11350 ENOG4105WR5 sporulation protein, YlmC YmxH family Ami103574_RS11355 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation Ami103574_RS11360 ENOG4105E65 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS11370 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) Ami103574_RS11380 ENOG4105BZ8 glutamate synthase Ami103574_RS11400 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS11415 ENOG4105VJV 50s ribosomal protein L35 Ami103574_RS11420 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) Ami103574_RS11425 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) Ami103574_RS11435 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) Ami103574_RS11440 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase Ami103574_RS11445 ENOG4108IAB Phoh family Ami103574_RS11460 ENOG4105DDN Pentapeptide repeat-containing protein Ami103574_RS11475 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS11495 ENOG4105C19 ABC transporter Ami103574_RS11500 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS11505 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami103574_RS11515 ENOG4108SDV Periplasmic Protein Ami103574_RS11520 ENOG4107SJW iron permease, FTR1 Ami103574_RS11525 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Ami103574_RS11530 ENOG4105C59 p-type ATPase Ami103574_RS11560 ENOG4105C0A alcohol dehydrogenase Ami103574_RS11580 ENOG4105BZU Histidine kinase Ami103574_RS11585 ENOG41064RH membrane protein YliF Ami103574_RS11590 ENOG4105C22 threonyL-tRNA synthetase Ami103574_RS11595 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) Ami103574_RS11650 ENOG4105C5H ABC transporter Ami103574_RS11680 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism Ami103574_RS11690 ENOG4105CNI cell division protein FtsW Ami103574_RS11700 ENOG4105DUM transcriptional regulator, lysR family Ami103574_RS11710 ENOG4105EHR propanediol utilization protein pduB Ami103574_RS11715 ENOG4105DJV ribulose-phosphate 3-epimerase Ami103574_RS11720 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) Ami103574_RS11725 ENOG4105D9P serine threonine protein kinase Ami103574_RS11735 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B Ami103574_RS11750 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) Ami103574_RS11755 ENOG4105C25 Primosomal protein n' Ami103574_RS11760 ENOG4105WPN DNA integration recombination invertion protein Ami103574_RS11765 ENOG4105N5T Radical SAM Protein Ami103574_RS11770 ENOG4107104 thymidine kinase Ami103574_RS11910 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein Ami103574_RS11915 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) Ami103574_RS11925 ENOG4105EUM DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity) Ami103574_RS11930 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) Ami103574_RS11935 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) Ami103574_RS11940 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) Ami103574_RS11945 ENOG4105C79 DNA protecting protein DprA Ami103574_RS11950 ENOG4105C0P Mg chelatase subunit ChlI Ami103574_RS11955 ENOG4105VFF UPF0102 protein Ami103574_RS11960 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) Ami103574_RS11985 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) Ami103574_RS11990 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) Ami103574_RS11995 ENOG41080XP Cbs domain Ami103574_RS12000 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) Ami103574_RS12010 ENOG4105CM2 brancheD-chain amino acid aminotransferase Ami103574_RS12015 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Ami103574_RS12020 ENOG4105XZU Preprotein translocase, subunit SecG Ami103574_RS12025 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) Ami103574_RS12030 ENOG4105CP7 Triose-phosphate isomerase Ami103574_RS12035 ENOG4105BZA Phosphoglycerate kinase Ami103574_RS12045 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami103574_RS12055 ENOG4105D6E homoserine dehydrogenase Ami103574_RS12060 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving Ami103574_RS12070 ENOG4107QSQ Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) Ami103574_RS12085 ENOG4108Q52 Methyltransferase cognate corrinoid protein Ami103574_RS12105 ENOG4108Q52 Methyltransferase cognate corrinoid protein Ami103574_RS12110 ENOG4106HBX Transcriptional Regulator AraC Family Ami103574_RS12120 ENOG4105KNY Microcompartments protein Ami103574_RS12135 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS12155 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami103574_RS12160 ENOG4107QTH restriction modification system DNA specificity domain Ami103574_RS12175 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor Ami103574_RS12185 ENOG4105CSM endonuclease III Ami103574_RS12215 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami103574_RS12220 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) Ami103574_RS12225 ENOG4105DRR Transcriptional regulator, GntR family Ami103574_RS12235 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) Ami103574_RS12240 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) Ami103574_RS12245 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) Ami103574_RS12250 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami103574_RS12255 ENOG4105ECC imidazole-glycerol-phosphate dehydratase Ami103574_RS12260 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) Ami103574_RS12275 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase Ami103574_RS12285 ENOG4105VZ8 Transcriptional regulator Ami103574_RS12290 ENOG4105CTQ phosphohexokinase Ami103574_RS12295 ENOG4105C0B DNA polymerase III (alpha subunit) Ami103574_RS12300 ENOG4105CSX c4-dicarboxylate anaerobic carrier Ami103574_RS12305 ENOG4105KTW ethanolamine utilization protein Ami103574_RS12310 ENOG4105M3W utilization protein Ami103574_RS12315 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Ami103574_RS12320 ENOG4108IQI permease Ami103574_RS12325 ENOG4105CJ2 (LipO)protein Ami103574_RS12355 ENOG4105CEP NADH dehydrogenase Ami103574_RS12380 ENOG4105CFP Peptidase U32 Ami103574_RS12455 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami103574_RS12465 ENOG4107VHA regulatoR Ami103574_RS12470 ENOG4108Z5V transcriptional regulator, merr family Ami103574_RS12475 ENOG4108R96 Methyltransferase, YaeB family Ami103574_RS12485 ENOG4105WMR Protein CrcB homolog Ami103574_RS12490 ENOG4105FCD Major Facilitator Ami103574_RS12495 ENOG4105H9W Short-chain dehydrogenase reductase Sdr Ami103574_RS12505 ENOG4108RAC Rubrerythrin Ami103574_RS12540 ENOG4105F1A Pyruvate formate-lyase Ami103574_RS12550 ENOG4107XVH Transcriptional regulator Ami103574_RS12575 ENOG4108KTQ Methyltransferase Ami103574_RS12585 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) Ami103574_RS12595 ENOG4105EWC Purine nucleoside phosphorylase Ami103574_RS12600 ENOG4105C98 muts2 protein Ami103574_RS12605 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) Ami103574_RS12610 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) Ami103574_RS12615 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) Ami103574_RS12620 ENOG4108RWN rrna methyltransferase Ami103574_RS12625 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) Ami103574_RS12630 ENOG4105K67 small basic protein Ami103574_RS12650 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) Ami103574_RS12660 ENOG4105CNI cell division protein FtsW Ami103574_RS12665 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) Ami103574_RS12670 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) Ami103574_RS12675 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) Ami103574_RS12680 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Ami103574_RS12685 ENOG4105CJN penicillin-binding protein Ami103574_RS12695 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) Ami103574_RS12700 ENOG4108V6E Cell division protein mraZ Ami103574_RS12720 ENOG4108I05 Binding-protein-dependent transport systems, inner membrane component Ami103574_RS12730 ENOG4108IY8 ABC, transporter Ami103574_RS12740 ENOG4105CUZ uba thif-type nad fad binding protein Ami103574_RS12745 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) Ami103574_RS12755 ENOG4105C3G gtp-binding protein Ami103574_RS12790 ENOG41060K3 Methyltransferase Ami103574_RS12795 ENOG4105MA4 psp1 domain protein Ami103574_RS12800 ENOG4105FA2 dna polymerase iii Ami103574_RS12805 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) Ami103574_RS12835 ENOG4105CFP Peptidase U32 Ami103574_RS12840 ENOG4105C02 permease Ami103574_RS12855 ENOG4108WYP Transcriptional regulator Ami103574_RS12860 ENOG4106V2I dimethylaminohydrolase Ami103574_RS12870 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain Ami103574_RS12875 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain Ami103574_RS12885 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic Ami103574_RS12890 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) Ami103574_RS12925 ENOG4105MT0 Sporulation transcriptional regulator spoiiid Ami103574_RS12930 ENOG4105BZU Histidine kinase Ami103574_RS12940 ENOG4105C5W Aldolase Ami103574_RS12950 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS12955 ENOG4105D7W serine acetyltransferase Ami103574_RS12960 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator Ami103574_RS12965 ENOG4105CNN ABC, transporter Ami103574_RS12970 ENOG4105C2J ABC transporter Ami103574_RS12975 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) Ami103574_RS12980 ENOG4105ETE Transcriptional regulator (LacI family Ami103574_RS13000 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) Ami103574_RS13005 ENOG4105CUB amino acid Ami103574_RS13010 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami103574_RS13015 ENOG4105BZU Histidine kinase Ami103574_RS13030 ENOG4105C0R drug resistance transporter emrb qaca subfamily Ami103574_RS13035 ENOG4105CW7 secretion protein, HlyD family Ami103574_RS13050 ENOG4105CDW Resistance protein Ami103574_RS13060 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) Ami103574_RS13070 ENOG4105C59 p-type ATPase Ami103574_RS13075 ENOG41079KZ Major Facilitator Superfamily Ami103574_RS13090 ENOG4105C5S asparaginyl-tRNA synthetase Ami103574_RS13095 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) Ami103574_RS13105 ENOG4105BZU Histidine kinase Ami103574_RS13125 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) Ami103574_RS13130 ENOG4108ZX0 Signal peptidase I Ami103574_RS13135 ENOG4105C3F Signal peptidase i Ami103574_RS13160 ENOG4105D2N Aldolase Ami103574_RS13180 ENOG41090A1 ferritin Ami103574_RS13185 ENOG4105DAP Nicotinate phosphoribosyltransferase Ami103574_RS13195 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) Ami103574_RS13200 ENOG4105BZN citrate synthase Ami103574_RS13230 ENOG4105CJ1 ABC, transporter Ami103574_RS13235 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) Ami103574_RS13260 ENOG4105C6E dna polymerase iii Ami103574_RS13270 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) Ami103574_RS13300 ENOG4108JYZ YitT family Ami103574_RS13305 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) Ami103574_RS13325 ENOG4105KNY Microcompartments protein Ami103574_RS13330 ENOG4105C0A alcohol dehydrogenase Ami103574_RS13335 ENOG4105KNY Microcompartments protein Ami103574_RS13355 ENOG4105KTW ethanolamine utilization protein Ami103574_RS13360 ENOG4105M3W utilization protein Ami103574_RS13365 ENOG4105F1A Pyruvate formate-lyase Ami103574_RS13375 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) Ami103574_RS13380 ENOG4105EHR propanediol utilization protein pduB Ami103574_RS13385 ENOG4105C2F Histidine kinase Ami103574_RS13395 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) Ami103574_RS13400 ENOG4108RE9 Phosphodiesterase Ami103574_RS13405 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) Ami103574_RS13410 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) Ami103574_RS13415 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) Ami103574_RS13420 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) Ami103574_RS13425 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) Ami103574_RS13430 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) Ami103574_RS13435 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) Ami103574_RS13450 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) Ami103574_RS13455 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) Ami103574_RS13460 ENOG410683Z Preprotein translocase SecE subunit Ami103574_RS13465 ENOG4105WDJ 50S ribosomal protein L33 Ami103574_RS13480 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein Ami103574_RS13495 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) Ami103574_RS13505 ENOG4105QIV RNA polymerase Ami103574_RS13510 ENOG4105C2N RNA methyltransferase TrmH family group 3 Ami103574_RS13515 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) Ami103574_RS13525 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) Ami103574_RS13540 ENOG4107ZE5 PPIases accelerate the folding of proteins Ami103574_RS13545 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) Ami103574_RS13550 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) Ami103574_RS13555 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) Ami103574_RS13560 ENOG4105CTP PilT protein domain protein Ami103574_RS13570 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic Ami103574_RS13575 ENOG4105BZU Histidine kinase Ami103574_RS13580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS13585 ENOG4107R7I amino acid Ami103574_RS13600 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) Ami103574_RS13605 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) Ami103574_RS13610 ENOG4105HDK L-asparaginase Ami103574_RS13615 ENOG4105C5S asparaginyl-tRNA synthetase Ami103574_RS13645 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami103574_RS13670 ENOG4105CRK lysyL-tRNA synthetase Ami103574_RS13680 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) Ami103574_RS13685 ENOG4108RAC Rubrerythrin Ami103574_RS13695 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) Ami103574_RS13700 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) Ami103574_RS13710 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein Ami103574_RS13730 ENOG4108K8K Transcriptional regulator Ami103574_RS13735 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) Ami103574_RS13740 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) Ami103574_RS13745 ENOG4105C5H ABC transporter Ami103574_RS13840 ENOG4105F8V Hydrolase, tatD family Ami103574_RS13855 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS13870 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) Ami103574_RS13880 ENOG4107ZYJ bioY protein Ami103574_RS13885 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase Ami103574_RS13910 ENOG4105D29 Helix-turn-helix type 11 domain protein Ami103574_RS13935 ENOG4105E0A ABC, transporter Ami103574_RS13940 ENOG4105EHG Permease protein Ami103574_RS13950 ENOG4106P55 Transcriptional regulator Ami103574_RS13965 ENOG4105DY9 regulatoR Ami103574_RS13985 ENOG41080UQ Transcriptional regulator Ami103574_RS14020 ENOG4105C32 Amino acid ABC transporter (Permease) Ami103574_RS14025 ENOG4105CF8 branched-chain amino acid ABC transporter, permease Ami103574_RS14030 ENOG4105C0Z ABC transporter Ami103574_RS14035 ENOG4108IV0 ABC, transporter Ami103574_RS14065 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) Ami103574_RS14070 ENOG4108UJD 30S ribosomal protein S9 Ami103574_RS14075 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) Ami103574_RS14090 ENOG4105DZW Dipeptidase Ami103574_RS14105 ENOG4105VZ8 Transcriptional regulator Ami103574_RS14110 ENOG4105D01 (LipO)protein Ami103574_RS14115 ENOG4108UMI ABC transporter, permease Ami103574_RS14120 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) Ami103574_RS14125 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS14130 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS14140 ENOG4108UIN ybak prolyl-trna synthetase associated region Ami103574_RS14165 ENOG4108REF Sporulation integral membrane protein ytvi Ami103574_RS14180 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) Ami103574_RS14190 ENOG4108903 Formimidoylglutamase Ami103574_RS14200 ENOG4108JUB Transcriptional regulator Ami103574_RS14210 ENOG4105K7K Transcriptional regulator Ami103574_RS14240 ENOG4107QP7 CoA-transferase subunit A Ami103574_RS14245 ENOG4105JHE Major Facilitator Superfamily Ami103574_RS14250 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) Ami103574_RS14270 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) Ami103574_RS14275 ENOG4108VXD carboxy-peptidase Ami103574_RS14295 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) Ami103574_RS14305 ENOG4108UQV Membrane Ami103574_RS14325 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) Ami103574_RS14330 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) Ami103574_RS14335 ENOG4105C5H ABC transporter Ami103574_RS14350 ENOG410801F ribosomal-protein-alanine acetyltransferase Ami103574_RS14355 ENOG41072GX Peptidase M22 Glycoprotease Ami103574_RS14360 ENOG4105K8N protein family UPF0079, ATPase Ami103574_RS14370 ENOG4108JJB ABC transporter Ami103574_RS14390 ENOG41081BK membrane protein-like protein Ami103574_RS14395 ENOG4107QSE Dipeptidase Ami103574_RS14405 ENOG41083MR nifu domain-containing protein Ami103574_RS14415 ENOG4105KY8 Rubrerythrin Ami103574_RS14435 ENOG4106M28 alanine racemase domain protein Ami103574_RS14440 ENOG4105CEY Amp-dependent synthetase and ligase Ami103574_RS14455 ENOG4105IIU Aminopeptidase Ami103574_RS14480 ENOG4105KVH Transcriptional regulator Ami103574_RS14495 ENOG4105C5H ABC transporter Ami103574_RS14500 ENOG4107RWI ethanolamine utilization protein eutJ Ami103574_RS14520 ENOG4105ENY Ethanolamine utilization protein eutH Ami103574_RS14525 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml Ami103574_RS14540 ENOG4105KNY Microcompartments protein Ami103574_RS14545 ENOG4105KNY Microcompartments protein Ami103574_RS14550 ENOG4105KNY Microcompartments protein Ami103574_RS14555 ENOG4106D67 ethanolamine utilization protein Ami103574_RS14560 ENOG4107FQ9 ethanolamine ammonia-lyase Ami103574_RS14565 ENOG4105CPD ethanolamine ammonia-lyase Ami103574_RS14570 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase Ami103574_RS14585 ENOG4105M3W utilization protein Ami103574_RS14590 ENOG4105KTW ethanolamine utilization protein Ami103574_RS14610 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS14625 ENOG4105BZ1 (ABC) transporter Ami103574_RS14640 ENOG4105VEQ Cold shock protein Ami103574_RS14665 ENOG4105DPZ Two component transcriptional regulator (Winged helix family Ami103574_RS14670 ENOG4105EFI regulatoR Ami103574_RS14675 ENOG4105BZU Histidine kinase Ami103574_RS14690 ENOG4105C11 sulfate adenylyltransferase), subunit 2 Ami103574_RS14705 ENOG4105ETE Transcriptional regulator (LacI family Ami103574_RS14715 ENOG4105ECW sulfate abc transporter Ami103574_RS14720 ENOG4108I5D sulfate abc transporter Ami103574_RS14725 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein Ami103574_RS14730 ENOG4105BZ1 (ABC) transporter Ami103574_RS14735 ENOG4105E0A ABC, transporter Ami103574_RS14740 ENOG4105EHG Permease protein Ami103574_RS14745 ENOG4105DQ5 transport system permease protein Ami103574_RS14750 ENOG4108V5C ABC transporter Ami103574_RS14760 ENOG4105T16 Transcriptional regulator (AraC family) Ami103574_RS14765 ENOG4107STQ Multicopper oxidase Ami103574_RS14780 ENOG4105KVH Transcriptional regulator Ami103574_RS14835 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination Ami103574_RS14850 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) Ami103574_RS14855 ENOG4105CHR reductase Ami103574_RS14860 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase Ami103574_RS14870 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) Ami103574_RS14875 ENOG4105BZF Glycosyl transferase (Group 1 Ami103574_RS14880 ENOG4107XGZ Hydrolase Ami103574_RS14900 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving Ami103574_RS14915 ENOG4105CFH Aspartokinase Ami103574_RS14935 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase Ami103574_RS14940 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) Ami103574_RS14950 ENOG4107QP7 CoA-transferase subunit A Ami103574_RS14955 ENOG4107CHF 5,6-aminomutase beta subunit Ami103574_RS14960 ENOG4105EQ5 D-Lysine 5,6-aminomutase alpha subunit Ami103574_RS14965 ENOG4105C98 muts2 protein Ami103574_RS14975 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein Ami103574_RS14980 ENOG4105FRY Dehydrogenase Ami103574_RS14985 ENOG4105FRY Dehydrogenase Ami103574_RS14995 ENOG4108UYI beta-alanyl-CoA ammonia lyase Ami103574_RS15000 ENOG4105CH7 arginosuccinase Ami103574_RS15010 ENOG4105CIN aminoacyl-histidine dipeptidase Ami103574_RS15030 ENOG4105BZ1 (ABC) transporter Ami103574_RS15040 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami103574_RS15040 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami103574_RS15055 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami103574_RS15090 ENOG4108IQI permease Ami103574_RS15105 ENOG4108JUB Transcriptional regulator Ami103574_RS15110 ENOG4108Z5V transcriptional regulator, merr family Ami103574_RS15115 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami103574_RS15135 ENOG4105FE9 pseudouridine synthase Ami103574_RS15140 ENOG4105ER2 Ompa motb domain protein Ami103574_RS15145 ENOG4105E14 MotA TolQ exbB proton channel Ami103574_RS15160 ENOG4105BZU Histidine kinase Ami103574_RS15190 ENOG4105CNA YD repeat protein Ami103574_RS15210 ENOG4105C8Q Methyl-accepting chemotaxis Ami103574_RS15215 ENOG4108RS6 transposase Ami103574_RS15220 ENOG4107QNG Phosphoribosylglycinamide synthetase Ami103574_RS15225 ENOG4105DC1 bifunctional purine biosynthesis protein purh Ami103574_RS15230 ENOG4108V3E phosphoribosylglycinamide formyltransferase Ami103574_RS15235 ENOG4105CXB phosphoribosylaminoimidazole synthetase Ami103574_RS15245 ENOG4105C8V SAICAR synthetase Ami103574_RS15250 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) Ami103574_RS15255 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii Ami103574_RS15265 ENOG41067MG lrgb family Ami103574_RS15285 ENOG4105DZ1 carboxypeptidase Ami103574_RS15310 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) Ami103574_RS15320 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) Ami103574_RS15325 ENOG4105EJQ L-serine dehydratase Ami103574_RS15335 ENOG4105E4C Lytic transglycosylase catalytic Ami103574_RS15345 ENOG4105BZU Histidine kinase Ami103574_RS15350 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) Ami103574_RS15355 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) Ami103574_RS15365 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) Ami103574_RS15370 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Ami103574_RS15375 ENOG4108KJP F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Ami103574_RS15380 ENOG4105VH4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Ami103574_RS15385 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) Ami103574_RS15395 ENOG4107QI1 Mate efflux family protein Ami103574_RS15400 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase Ami103574_RS15405 ENOG4105ESV Glycosyl transferase, family 4 Ami103574_RS15410 ENOG4108Z6B deaminase Ami103574_RS15415 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) Ami103574_RS15420 ENOG410812S Rna-binding protein Ami103574_RS15425 ENOG4105BZU Histidine kinase Ami103574_RS15435 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase Ami103574_RS15445 ENOG4105CDA abc transporter atp-binding protein Ami103574_RS15450 ENOG4105E5Q amino acid AbC transporter Ami103574_RS15455 ENOG4106PMH Extracellular solute-binding protein family 3 Ami103574_RS15465 ENOG4105CHU acetyl-coa acetyltransferase Ami103574_RS15475 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) Ami103574_RS15480 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase Ami103574_RS15485 ENOG4105BZU Histidine kinase Ami103574_RS15490 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami103574_RS15500 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) Ami103574_RS15505 ENOG4105E2Z phosphate ABC transporter (Permease Ami103574_RS15510 ENOG4105C8U phosphate abc transporter Ami103574_RS15520 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) Ami103574_RS15525 ENOG4108V4M Cobalt abc transporter Ami103574_RS15530 ENOG4108JJB ABC transporter Ami103574_RS15535 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) Ami103574_RS15545 ENOG4105CA9 Pyruvate kinase Ami103574_RS15565 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Ami103574_RS15575 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami103574_RS15620 ENOG4105DQ6 Transposase