locus-tag	class	description
DCS14_RS00005	COG1192	Involved in chromosome partitioning
DCS14_RS00010	COG1475	DNA binding
DCS14_RS00015	COG0640	Transcriptional regulator
DCS14_RS00020	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCS14_RS00025	COG3657	addiction module killer protein
DCS14_RS00030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DCS14_RS00035	COG1959	2 iron, 2 sulfur cluster binding
DCS14_RS00055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DCS14_RS00070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS00095	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCS14_RS00165	COG4974	Belongs to the 'phage' integrase family
DCS14_RS00170	COG0582	viral genome integration into host DNA
DCS14_RS00175	COG4974	Belongs to the 'phage' integrase family
DCS14_RS00205	COG0582	viral genome integration into host DNA
DCS14_RS00255	COG3504	Conjugal transfer protein
DCS14_RS00260	COG3701	Conjugal transfer protein
DCS14_RS00265	COG3846	protein secretion by the type IV secretion system
DCS14_RS00275	COG5314	conjugation
DCS14_RS00280	COG3451	type IV secretory pathway VirB4
DCS14_RS00290	COG3838	Conjugal transfer protein Trbc
DCS14_RS00295	COG4962	Type ii secretion system protein e
DCS14_RS00320	COG4962	Type ii secretion system protein e
DCS14_RS00325	COG3838	Conjugal transfer protein Trbc
DCS14_RS00330	COG5268	conjugation
DCS14_RS00355	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS00390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCS14_RS00500	COG3077	Addiction module antitoxin, RelB DinJ family
DCS14_RS00505	COG3041	Addiction module toxin RelE StbE family
DCS14_RS00515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCS14_RS00525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DCS14_RS00550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCS14_RS00560	COG0735	belongs to the Fur family
DCS14_RS00565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DCS14_RS00575	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DCS14_RS00580	COG3300	MHYT domain
DCS14_RS00580	COG5001	Diguanylate cyclase
DCS14_RS00585	COG2813	Specifically methylates the guanine in position
DCS14_RS00590	COG1185	polyribonucleotide nucleotidyltransferase activity
DCS14_RS00595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCS14_RS00600	COG0598	Magnesium transport protein CorA
DCS14_RS00605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCS14_RS00610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DCS14_RS00615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCS14_RS00630	COG0779	Required for maturation of 30S ribosomal subunits
DCS14_RS00665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DCS14_RS00670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DCS14_RS00675	COG1396	sequence-specific DNA binding
DCS14_RS00680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DCS14_RS00690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DCS14_RS00695	COG1702	phosphate starvation-inducible protein PhoH
DCS14_RS00700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCS14_RS00705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DCS14_RS00730	COG1214	PFAM Peptidase M22, glycoprotease
DCS14_RS00740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DCS14_RS00770	COG2827	Endonuclease containing a URI domain
DCS14_RS00775	COG0481	GTPase activity
DCS14_RS00820	COG2827	Endonuclease containing a URI domain
DCS14_RS00840	COG0671	phosphoesterase, PA-phosphatase related
DCS14_RS00850	COG0659	secondary active sulfate transmembrane transporter activity
DCS14_RS00855	COG0443	Heat shock 70 kDa protein
DCS14_RS00875	COG3795	YCII-related domain
DCS14_RS00910	COG0640	Transcriptional regulator
DCS14_RS00915	COG0625	glutathione transferase activity
DCS14_RS00930	COG2358	TRAP transporter, solute receptor (TAXI family
DCS14_RS00935	COG0842	Transport permease protein
DCS14_RS00940	COG1131	(ABC) transporter
DCS14_RS00955	COG2954	triphosphatase activity
DCS14_RS00980	COG1420	regulation of RNA biosynthetic process
DCS14_RS00985	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DCS14_RS00995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCS14_RS01000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DCS14_RS01015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DCS14_RS01020	COG0792	nuclease activity
DCS14_RS01030	COG1254	Belongs to the acylphosphatase family
DCS14_RS01035	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DCS14_RS01040	COG2124	cytochrome p450
DCS14_RS01055	COG3920	Histidine kinase
DCS14_RS01070	COG0024	Methionine aminopeptidase
DCS14_RS01080	COG2205	protein histidine kinase activity
DCS14_RS01085	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DCS14_RS01090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DCS14_RS01095	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DCS14_RS01110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DCS14_RS01125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DCS14_RS01130	COG2226	methyltransferase
DCS14_RS01135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCS14_RS01140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DCS14_RS01160	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DCS14_RS01180	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS01185	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS01190	COG3845	ABC transporter
DCS14_RS01195	COG2900	Belongs to the SlyX family
DCS14_RS01205	COG1744	ABC transporter substrate-binding protein PnrA-like
DCS14_RS01210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS14_RS01235	COG0583	DNA-binding transcription factor activity
DCS14_RS01240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DCS14_RS01250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DCS14_RS01255	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS01265	COG4172	Belongs to the ABC transporter superfamily
DCS14_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS01275	COG0601	transmembrane transport
DCS14_RS01280	COG4166	transmembrane transport
DCS14_RS01290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS01295	COG1473	amidohydrolase
DCS14_RS01300	COG4166	transmembrane transport
DCS14_RS01350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCS14_RS01370	COG0395	ABC-type sugar transport system, permease component
DCS14_RS01375	COG1175	transmembrane transport
DCS14_RS01390	COG1765	OsmC-like protein
DCS14_RS01395	COG2766	serine protein kinase
DCS14_RS01400	COG2718	Belongs to the UPF0229 family
DCS14_RS01405	COG2719	SpoVR family
DCS14_RS01410	COG3142	Participates in the control of copper homeostasis
DCS14_RS01415	COG1940	carbohydrate kinase activity
DCS14_RS01425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS01430	COG1446	asparaginase
DCS14_RS01440	COG0765	amino acid transport
DCS14_RS01445	COG0765	amino acid transport
DCS14_RS01515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DCS14_RS01520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS01525	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS01530	COG1957	nucleoside hydrolase
DCS14_RS01545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCS14_RS01550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCS14_RS01555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DCS14_RS01560	COG1137	ATPase activity
DCS14_RS01565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DCS14_RS01575	COG0616	signal peptide processing
DCS14_RS01580	COG0776	regulation of translation
DCS14_RS01590	COG2423	ornithine cyclodeaminase activity
DCS14_RS01595	COG0116	Belongs to the methyltransferase superfamily
DCS14_RS01595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DCS14_RS01605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DCS14_RS01635	COG1252	NADH dehydrogenase
DCS14_RS01645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DCS14_RS01660	COG0175	sulfate reduction
DCS14_RS01665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DCS14_RS01675	COG1648	precorrin-2 dehydrogenase activity
DCS14_RS01675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DCS14_RS01685	COG4651	solute:proton antiporter activity
DCS14_RS01685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DCS14_RS01695	COG1846	Transcriptional regulator
DCS14_RS01705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DCS14_RS01735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCS14_RS01750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCS14_RS01750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCS14_RS01755	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS01765	COG0667	Aldo Keto reductase
DCS14_RS01770	COG0673	inositol 2-dehydrogenase activity
DCS14_RS01785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DCS14_RS01795	COG1609	Transcriptional regulator
DCS14_RS01800	COG1653	transport
DCS14_RS01805	COG1175	transmembrane transport
DCS14_RS01810	COG0395	ABC-type sugar transport system, permease component
DCS14_RS01815	COG0366	Alpha amylase catalytic
DCS14_RS01820	COG3842	ATPase activity
DCS14_RS01825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCS14_RS01830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCS14_RS01835	COG1121	(ABC) transporter
DCS14_RS01840	COG0803	Belongs to the bacterial solute-binding protein 9 family
DCS14_RS01855	COG1404	Belongs to the peptidase S8 family
DCS14_RS01865	COG1595	DNA-templated transcription, initiation
DCS14_RS01875	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS01880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS01890	COG0747	negative chemotaxis
DCS14_RS01895	COG2936	dipeptidyl-peptidase activity
DCS14_RS01900	COG1309	transcriptional regulator
DCS14_RS01985	COG4974	Belongs to the 'phage' integrase family
DCS14_RS01995	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS02000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS02015	COG2814	Major facilitator Superfamily
DCS14_RS02050	COG2814	Major facilitator Superfamily
DCS14_RS02090	COG0583	DNA-binding transcription factor activity
DCS14_RS02100	COG0251	oxidation-reduction process
DCS14_RS02125	COG0583	DNA-binding transcription factor activity
DCS14_RS02130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS02200	COG0765	amino acid transport
DCS14_RS02205	COG0765	amino acid transport
DCS14_RS02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS02215	COG1126	abc transporter atp-binding protein
DCS14_RS02230	COG2072	flavoprotein involved in K transport
DCS14_RS02235	COG0583	DNA-binding transcription factor activity
DCS14_RS02270	COG1136	(ABC) transporter
DCS14_RS02270	COG0577	efflux transmembrane transporter activity
DCS14_RS02320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS02325	COG0601	transmembrane transport
DCS14_RS02345	COG2197	response regulator
DCS14_RS02355	COG0583	DNA-binding transcription factor activity
DCS14_RS02395	COG3451	type IV secretory pathway VirB4
DCS14_RS02405	COG3838	Conjugal transfer protein Trbc
DCS14_RS02410	COG4962	Type ii secretion system protein e
DCS14_RS02490	COG5489	Protein of unknown function (DUF736)
DCS14_RS02570	COG1072	(Pantothenic acid kinase))
DCS14_RS02580	COG0625	glutathione transferase activity
DCS14_RS02595	COG0829	nickel cation binding
DCS14_RS02600	COG0831	urea catabolic process
DCS14_RS02605	COG3813	Protein conserved in bacteria
DCS14_RS02610	COG0832	Belongs to the urease beta subunit family
DCS14_RS02630	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DCS14_RS02635	COG0830	nickel cation binding
DCS14_RS02645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DCS14_RS02655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCS14_RS02665	COG0583	DNA-binding transcription factor activity
DCS14_RS02670	COG0534	Mate efflux family protein
DCS14_RS02680	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS02685	COG3842	ATPase activity
DCS14_RS02695	COG0765	amino acid transport
DCS14_RS02700	COG0765	amino acid transport
DCS14_RS02715	COG0583	DNA-binding transcription factor activity
DCS14_RS02720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DCS14_RS02735	COG0559	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS02745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCS14_RS02760	COG1335	isochorismatase
DCS14_RS02770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DCS14_RS02790	COG1846	Transcriptional regulator
DCS14_RS02795	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS02800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DCS14_RS02825	COG0673	inositol 2-dehydrogenase activity
DCS14_RS02830	COG0395	ABC-type sugar transport system, permease component
DCS14_RS02835	COG1175	transmembrane transport
DCS14_RS02845	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DCS14_RS02850	COG2971	BadF BadG BcrA BcrD
DCS14_RS02855	COG2188	Transcriptional regulator
DCS14_RS02865	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DCS14_RS02885	COG1879	ABC-type sugar transport system periplasmic component
DCS14_RS02890	COG1129	ABC transporter
DCS14_RS02895	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS02900	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS02905	COG1609	Transcriptional regulator
DCS14_RS02915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS02925	COG4941	Belongs to the sigma-70 factor family
DCS14_RS02930	COG3795	YCII-related domain
DCS14_RS02935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS02975	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DCS14_RS02980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DCS14_RS02985	COG4335	DNA alkylation repair
DCS14_RS03015	COG0121	glutamine amidotransferase
DCS14_RS03020	COG0756	dUTP diphosphatase activity
DCS14_RS03025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCS14_RS03030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DCS14_RS03040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS03065	COG0280	phosphate acetyltransferase
DCS14_RS03065	COG0281	malic enzyme
DCS14_RS03070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DCS14_RS03115	COG0596	Alpha beta hydrolase
DCS14_RS03120	COG2207	Transcriptional regulator
DCS14_RS03120	COG0662	Cupin 2, conserved barrel domain protein
DCS14_RS03130	COG1309	transcriptional regulator
DCS14_RS03150	COG5001	Diguanylate cyclase
DCS14_RS03150	COG5002	protein histidine kinase activity
DCS14_RS03160	COG0656	L-ascorbic acid biosynthetic process
DCS14_RS03175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DCS14_RS03180	COG0728	peptidoglycan biosynthetic process
DCS14_RS03185	COG0180	Tryptophanyl-tRNA synthetase
DCS14_RS03195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DCS14_RS03200	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS03210	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DCS14_RS03220	COG1643	Atp-dependent helicase
DCS14_RS03245	COG0673	inositol 2-dehydrogenase activity
DCS14_RS03250	COG1737	Transcriptional regulator
DCS14_RS03255	COG0129	dihydroxy-acid dehydratase activity
DCS14_RS03265	COG0626	cystathionine gamma-synthase activity
DCS14_RS03270	COG1846	Transcriptional regulator
DCS14_RS03275	COG0697	spore germination
DCS14_RS03280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS03285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DCS14_RS03290	COG4521	taurine ABC transporter
DCS14_RS03300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCS14_RS03305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCS14_RS03315	COG1137	ATPase activity
DCS14_RS03335	COG0683	leucine binding
DCS14_RS03350	COG3485	protocatechuate 3,4-dioxygenase
DCS14_RS03355	COG3485	protocatechuate 3,4-dioxygenase
DCS14_RS03360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DCS14_RS03365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS03370	COG0583	DNA-binding transcription factor activity
DCS14_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS03380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCS14_RS03385	COG1802	Transcriptional regulator
DCS14_RS03390	COG0579	oxidoreductase
DCS14_RS03400	COG1522	sequence-specific DNA binding
DCS14_RS03405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DCS14_RS03410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS03420	COG1196	nuclear chromosome segregation
DCS14_RS03420	COG0741	lytic transglycosylase activity
DCS14_RS03420	COG0739	heme binding
DCS14_RS03445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS03455	COG3395	kinase activity
DCS14_RS03460	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS03465	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS03470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS03480	COG0747	negative chemotaxis
DCS14_RS03485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DCS14_RS03490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS14_RS03500	COG1454	alcohol dehydrogenase
DCS14_RS03535	COG1022	Amp-dependent synthetase and ligase
DCS14_RS03545	COG0861	Integral membrane protein TerC family
DCS14_RS03595	COG0156	8-amino-7-oxononanoate synthase activity
DCS14_RS03600	COG1063	alcohol dehydrogenase
DCS14_RS03610	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS03620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS03625	COG0601	transmembrane transport
DCS14_RS03640	COG2186	Transcriptional regulator
DCS14_RS03655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DCS14_RS03660	COG0400	carboxylic ester hydrolase activity
DCS14_RS03670	COG2124	cytochrome p450
DCS14_RS03685	COG4206	TonB-dependent receptor
DCS14_RS03700	COG1120	ATPase activity
DCS14_RS03715	COG0848	biopolymer transport protein
DCS14_RS03760	COG1082	Xylose isomerase domain protein TIM barrel
DCS14_RS03765	COG4607	ABC-type enterochelin transport system periplasmic component
DCS14_RS03770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS03775	COG4605	iron ion homeostasis
DCS14_RS03780	COG4604	ABC transporter, ATP-binding protein
DCS14_RS03790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS03810	COG0559	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS03820	COG2271	Major facilitator Superfamily
DCS14_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS03840	COG4638	Rieske (2fe-2S)
DCS14_RS03865	COG0640	Transcriptional regulator
DCS14_RS03870	COG0798	PFAM Bile acid sodium symporter
DCS14_RS03880	COG0431	NADPH-dependent FMN reductase
DCS14_RS03890	COG4974	Belongs to the 'phage' integrase family
DCS14_RS03965	COG4957	zinc ion binding
DCS14_RS03970	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DCS14_RS03990	COG1953	Uracil, thiamine, allantoin
DCS14_RS04015	COG0583	DNA-binding transcription factor activity
DCS14_RS04050	COG2801	Transposase and inactivated derivatives
DCS14_RS04065	COG3436	PFAM IS66 Orf2 family protein
DCS14_RS04080	COG0006	proline dipeptidase activity
DCS14_RS04090	COG1129	ABC transporter
DCS14_RS04095	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS04130	COG2801	Transposase and inactivated derivatives
DCS14_RS04140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS04140	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS04155	COG4977	sequence-specific DNA binding
DCS14_RS04190	COG3842	ATPase activity
DCS14_RS04200	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS04210	COG0583	DNA-binding transcription factor activity
DCS14_RS04240	COG0010	Belongs to the arginase family
DCS14_RS04260	COG0583	DNA-binding transcription factor activity
DCS14_RS04265	COG2423	ornithine cyclodeaminase activity
DCS14_RS04270	COG3616	Alanine racemase, N-terminal domain
DCS14_RS04275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCS14_RS04280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DCS14_RS04300	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS04305	COG3842	ATPase activity
DCS14_RS04315	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS04370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DCS14_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS04380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DCS14_RS04385	COG0539	negative regulation of cytoplasmic translation
DCS14_RS04405	COG1309	transcriptional regulator
DCS14_RS04430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DCS14_RS04440	COG3237	CsbD-like
DCS14_RS04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCS14_RS04455	COG1968	undecaprenyl-diphosphatase activity
DCS14_RS04465	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DCS14_RS04475	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
DCS14_RS04480	COG1803	Methylglyoxal synthase
DCS14_RS04485	COG0837	glucose binding
DCS14_RS04490	COG1132	(ABC) transporter
DCS14_RS04495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DCS14_RS04500	COG0588	phosphoglycerate mutase activity
DCS14_RS04510	COG0463	Glycosyl transferase, family 2
DCS14_RS04515	COG1295	ribonuclease BN
DCS14_RS04540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DCS14_RS04550	COG3386	PFAM SMP-30 Gluconolaconase
DCS14_RS04555	COG0800	Aldolase
DCS14_RS04560	COG3734	2-keto-3-deoxy-galactonokinase
DCS14_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS04570	COG5001	Diguanylate cyclase
DCS14_RS04575	COG0189	ligase activity
DCS14_RS04585	COG5001	Diguanylate cyclase
DCS14_RS04765	COG0305	Participates in initiation and elongation during chromosome replication
DCS14_RS04800	COG4974	Belongs to the 'phage' integrase family
DCS14_RS04830	COG0284	orotidine-5'-phosphate decarboxylase activity
DCS14_RS04840	COG3963	phosphatidate phosphatase activity
DCS14_RS04845	COG0484	heat shock protein binding
DCS14_RS04850	COG0443	Heat shock 70 kDa protein
DCS14_RS04880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCS14_RS04880	COG0072	phenylalanine-tRNA ligase activity
DCS14_RS04890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DCS14_RS04895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCS14_RS04900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DCS14_RS04910	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCS14_RS04920	COG3135	benzoate transporter
DCS14_RS04935	COG0135	phosphoribosylanthranilate isomerase activity
DCS14_RS04940	COG0133	tryptophan synthase activity
DCS14_RS04945	COG0159	tryptophan synthase activity
DCS14_RS04950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DCS14_RS04965	COG1074	ATP-dependent DNA helicase activity
DCS14_RS04970	COG2887	Belongs to the helicase family. UvrD subfamily
DCS14_RS04975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DCS14_RS04980	COG3178	'Phosphotransferase
DCS14_RS04985	COG2205	protein histidine kinase activity
DCS14_RS04990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DCS14_RS04995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCS14_RS05000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DCS14_RS05000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCS14_RS05010	COG2205	protein histidine kinase activity
DCS14_RS05015	COG0745	RESPONSE REGULATOR receiver
DCS14_RS05020	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DCS14_RS05030	COG1652	LysM domain
DCS14_RS05040	COG1072	(Pantothenic acid kinase))
DCS14_RS05045	COG0140	phosphoribosyl-ATP diphosphatase activity
DCS14_RS05050	COG0107	imidazoleglycerol-phosphate synthase activity
DCS14_RS05055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DCS14_RS05060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DCS14_RS05070	COG0131	Imidazoleglycerol-phosphate dehydratase
DCS14_RS05075	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DCS14_RS05095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DCS14_RS05105	COG3800	Transcriptional regulator
DCS14_RS05105	COG1396	sequence-specific DNA binding
DCS14_RS05130	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DCS14_RS05135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DCS14_RS05140	COG0237	dephospho-CoA kinase activity
DCS14_RS05145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCS14_RS05150	COG0424	maF-like protein
DCS14_RS05155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DCS14_RS05160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DCS14_RS05165	COG1981	membrane
DCS14_RS05170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DCS14_RS05175	COG1331	Highly conserved protein containing a thioredoxin domain
DCS14_RS05180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DCS14_RS05185	COG0445	tRNA wobble uridine modification
DCS14_RS05190	COG0357	Ribosomal RNA small subunit methyltransferase G
DCS14_RS05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DCS14_RS05270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DCS14_RS05270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DCS14_RS05280	COG4770	biotin carboxylase activity
DCS14_RS05285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCS14_RS05290	COG1268	BioY protein
DCS14_RS05295	COG1396	sequence-specific DNA binding
DCS14_RS05295	COG3800	Transcriptional regulator
DCS14_RS05305	COG2183	response to ionizing radiation
DCS14_RS05310	COG0137	argininosuccinate synthase activity
DCS14_RS05345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DCS14_RS05350	COG0287	Prephenate dehydrogenase
DCS14_RS05350	COG1605	Chorismate mutase
DCS14_RS05355	COG0228	four-way junction DNA binding
DCS14_RS05365	COG3781	membrane
DCS14_RS05375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DCS14_RS05390	COG4178	(ABC) transporter
DCS14_RS05395	COG3152	Membrane
DCS14_RS05400	COG0473	3-isopropylmalate dehydrogenase activity
DCS14_RS05415	COG0251	oxidation-reduction process
DCS14_RS05425	COG0066	3-isopropylmalate dehydratase activity
DCS14_RS05430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DCS14_RS05435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS05440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS05460	COG2814	Major facilitator Superfamily
DCS14_RS05520	COG1278	Cold shock
DCS14_RS05540	COG2301	Belongs to the HpcH HpaI aldolase family
DCS14_RS05565	COG0587	DNA-directed DNA polymerase activity
DCS14_RS05570	COG2835	tetraacyldisaccharide 4'-kinase activity
DCS14_RS05575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DCS14_RS05580	COG3118	belongs to the thioredoxin family
DCS14_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS05600	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS05605	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCS14_RS05615	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS05620	COG1129	ABC transporter
DCS14_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS05645	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS05650	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS05655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS05660	COG0601	transmembrane transport
DCS14_RS05665	COG0747	negative chemotaxis
DCS14_RS05675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCS14_RS05690	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DCS14_RS05700	COG0456	acetyltransferase
DCS14_RS05710	COG3339	Conserved Protein
DCS14_RS05715	COG2154	pterin-4-alpha-carbinolamine dehydratase
DCS14_RS05720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCS14_RS05725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DCS14_RS05735	COG1136	(ABC) transporter
DCS14_RS05745	COG0670	Belongs to the BI1 family
DCS14_RS05755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DCS14_RS05760	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS05785	COG5001	Diguanylate cyclase
DCS14_RS05785	COG3300	MHYT domain
DCS14_RS05820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DCS14_RS05830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DCS14_RS05835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCS14_RS05840	COG0552	protein localization to endoplasmic reticulum
DCS14_RS05845	COG2917	probably involved in intracellular septation
DCS14_RS05860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DCS14_RS05870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DCS14_RS05875	COG4133	protoheme IX ABC transporter activity
DCS14_RS05880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DCS14_RS05885	COG0039	L-malate dehydrogenase activity
DCS14_RS05890	COG0045	succinate-CoA ligase (ADP-forming) activity
DCS14_RS05895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DCS14_RS05900	COG0567	Dehydrogenase, E1 component
DCS14_RS05905	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS14_RS05920	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS05955	COG4974	Belongs to the 'phage' integrase family
DCS14_RS05960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCS14_RS05975	COG0336	Belongs to the RNA methyltransferase TrmD family
DCS14_RS05995	COG0335	large ribosomal subunit rRNA binding
DCS14_RS06005	COG0765	amino acid transport
DCS14_RS06010	COG2226	methyltransferase
DCS14_RS06025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCS14_RS06040	COG2009	succinate dehydrogenase
DCS14_RS06070	COG3132	Protein of unknown function, DUF480
DCS14_RS06085	COG1764	response to oxidative stress
DCS14_RS06090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCS14_RS06095	COG1946	Acyl-CoA thioesterase
DCS14_RS06100	COG0347	Belongs to the P(II) protein family
DCS14_RS06105	COG0004	ammonium transporteR
DCS14_RS06130	COG1674	ftsk spoiiie
DCS14_RS06130	COG2261	transglycosylase associated protein
DCS14_RS06135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DCS14_RS06150	COG0745	RESPONSE REGULATOR receiver
DCS14_RS06165	COG0583	DNA-binding transcription factor activity
DCS14_RS06185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DCS14_RS06190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCS14_RS06195	COG0181	hydroxymethylbilane synthase activity
DCS14_RS06235	COG2755	lipolytic protein G-D-S-L family
DCS14_RS06235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCS14_RS06245	COG3239	Fatty acid desaturase
DCS14_RS06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCS14_RS06260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCS14_RS06270	COG4176	ABC-type proline glycine betaine transport system permease component
DCS14_RS06275	COG3448	diguanylate cyclase activity
DCS14_RS06275	COG4175	Glycine betaine
DCS14_RS06295	COG1879	ABC-type sugar transport system periplasmic component
DCS14_RS06300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS06305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCS14_RS06310	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS06330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DCS14_RS06350	COG1872	DUF167
DCS14_RS06360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DCS14_RS06385	COG1704	LemA family
DCS14_RS06410	COG2814	Major facilitator Superfamily
DCS14_RS06430	COG1217	gtp-binding protein TYPA
DCS14_RS06450	COG2270	Major facilitator Superfamily
DCS14_RS06455	COG0138	bifunctional purine biosynthesis protein purh
DCS14_RS06470	COG0501	Belongs to the peptidase M48B family
DCS14_RS06490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS14_RS06495	COG5425	PFAM Usg family protein
DCS14_RS06520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DCS14_RS06525	COG0495	leucyl-tRNA aminoacylation
DCS14_RS06545	COG1522	sequence-specific DNA binding
DCS14_RS06550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DCS14_RS06580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCS14_RS06590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DCS14_RS06595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DCS14_RS06600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DCS14_RS06610	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DCS14_RS06615	COG1088	dTDP-glucose 4,6-dehydratase activity
DCS14_RS06620	COG1091	dTDP-4-dehydrorhamnose reductase activity
DCS14_RS06630	COG3754	Rhamnan synthesis protein F
DCS14_RS06640	COG3754	Rhamnan synthesis protein F
DCS14_RS06645	COG3842	ATPase activity
DCS14_RS06650	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS06655	COG1082	Xylose isomerase domain protein TIM barrel
DCS14_RS06665	COG0395	ABC-type sugar transport system, permease component
DCS14_RS06670	COG1175	transmembrane transport
DCS14_RS06680	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS06685	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS06700	COG4533	DNA binding
DCS14_RS06705	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS06730	COG0459	protein refolding
DCS14_RS06735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DCS14_RS06755	COG0514	ATP-dependent DNA helicase (RecQ)
DCS14_RS06760	COG0582	viral genome integration into host DNA
DCS14_RS06855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCS14_RS06860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DCS14_RS06875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DCS14_RS06880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DCS14_RS06885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DCS14_RS06890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DCS14_RS06910	COG0799	negative regulation of ribosome biogenesis
DCS14_RS06915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DCS14_RS06925	COG0793	Belongs to the peptidase S41A family
DCS14_RS06935	COG0494	nUDIX hydrolase
DCS14_RS06940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS06950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS06985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS14_RS06990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS07030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DCS14_RS07040	COG2223	nitrite transmembrane transporter activity
DCS14_RS07050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCS14_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS07080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DCS14_RS07085	COG0741	lytic transglycosylase activity
DCS14_RS07090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCS14_RS07105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DCS14_RS07110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DCS14_RS07125	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DCS14_RS07130	COG0183	Belongs to the thiolase family
DCS14_RS07135	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS07140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DCS14_RS07155	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DCS14_RS07160	COG1329	Transcriptional regulator
DCS14_RS07165	COG1126	abc transporter atp-binding protein
DCS14_RS07170	COG0765	amino acid transport
DCS14_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS07180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCS14_RS07190	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DCS14_RS07200	COG4143	(ABC) transporter
DCS14_RS07210	COG0488	(ABC) transporter
DCS14_RS07230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DCS14_RS07240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS07245	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DCS14_RS07260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCS14_RS07275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCS14_RS07280	COG0037	tRNA processing
DCS14_RS07290	COG2885	chlorophyll binding
DCS14_RS07295	COG0823	Involved in the tonB-independent uptake of proteins
DCS14_RS07305	COG0848	biopolymer transport protein
DCS14_RS07315	COG0824	Thioesterase
DCS14_RS07325	COG0456	acetyltransferase
DCS14_RS07325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCS14_RS07330	COG2255	four-way junction helicase activity
DCS14_RS07345	COG0632	four-way junction helicase activity
DCS14_RS07365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DCS14_RS07385	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS07405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DCS14_RS07410	COG0483	inositol monophosphate 1-phosphatase activity
DCS14_RS07415	COG1272	protein, Hemolysin III
DCS14_RS07455	COG1132	(ABC) transporter
DCS14_RS07460	COG0254	rRNA binding
DCS14_RS07470	COG0702	epimerase
DCS14_RS07480	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCS14_RS07490	COG0217	transcriptional regulatory protein
DCS14_RS07500	COG3706	GGDEF domain
DCS14_RS07510	COG1733	regulation of RNA biosynthetic process
DCS14_RS07530	COG0305	Participates in initiation and elongation during chromosome replication
DCS14_RS07535	COG0861	Integral membrane protein TerC family
DCS14_RS07540	COG1692	metallophosphoesterase
DCS14_RS07580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS14_RS07590	COG3750	Belongs to the UPF0335 family
DCS14_RS07610	COG0469	pyruvate kinase activity
DCS14_RS07615	COG2267	carboxylic ester hydrolase activity
DCS14_RS07620	COG0457	Tetratricopeptide repeat
DCS14_RS07635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DCS14_RS07655	COG0640	Transcriptional regulator
DCS14_RS07670	COG3321	synthase
DCS14_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS07670	COG0604	alcohol dehydrogenase
DCS14_RS07700	COG4191	Histidine kinase
DCS14_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS07845	COG3588	fructose-bisphosphate aldolase
DCS14_RS07850	COG0126	phosphoglycerate kinase activity
DCS14_RS07885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCS14_RS07890	COG0564	pseudouridine synthase activity
DCS14_RS07900	COG0346	lactoylglutathione lyase activity
DCS14_RS07965	COG1525	nuclease
DCS14_RS08100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DCS14_RS08150	COG5002	protein histidine kinase activity
DCS14_RS08150	COG2205	protein histidine kinase activity
DCS14_RS08150	COG0784	Response regulator, receiver
DCS14_RS08160	COG0573	inorganic phosphate transmembrane transporter activity
DCS14_RS08170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCS14_RS08175	COG0704	Plays a role in the regulation of phosphate uptake
DCS14_RS08180	COG0745	RESPONSE REGULATOR receiver
DCS14_RS08195	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS08215	COG4213	ABC transporter substrate-binding protein
DCS14_RS08220	COG4214	carbohydrate transport
DCS14_RS08245	COG2202	Pas domain
DCS14_RS08245	COG3920	Histidine kinase
DCS14_RS08255	COG0784	Response regulator, receiver
DCS14_RS08275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DCS14_RS08325	COG0346	lactoylglutathione lyase activity
DCS14_RS08330	COG0400	carboxylic ester hydrolase activity
DCS14_RS08345	COG2199	diguanylate cyclase activity
DCS14_RS08345	COG2200	EAL domain
DCS14_RS08345	COG2203	Gaf domain
DCS14_RS08355	COG0745	RESPONSE REGULATOR receiver
DCS14_RS08370	COG1178	ABC-type Fe3 transport system permease component
DCS14_RS08375	COG3842	ATPase activity
DCS14_RS08395	COG0483	inositol monophosphate 1-phosphatase activity
DCS14_RS08400	COG0483	inositol monophosphate 1-phosphatase activity
DCS14_RS08425	COG1840	ABC-type Fe3 transport system, periplasmic component
DCS14_RS08435	COG3842	ATPase activity
DCS14_RS08440	COG1238	metal cluster binding
DCS14_RS08450	COG2132	Multicopper oxidase
DCS14_RS08475	COG2217	Heavy metal translocating P-type atpase
DCS14_RS08480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DCS14_RS08485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DCS14_RS08495	COG1845	cytochrome c oxidase, subunit III
DCS14_RS08525	COG3842	ATPase activity
DCS14_RS08530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DCS14_RS08550	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS08555	COG4603	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS08560	COG3845	ABC transporter
DCS14_RS08570	COG2186	Transcriptional regulator
DCS14_RS08590	COG0625	glutathione transferase activity
DCS14_RS08595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DCS14_RS08600	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DCS14_RS08615	COG2022	thiamine diphosphate biosynthetic process
DCS14_RS08630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DCS14_RS08640	COG0022	dehydrogenase e1 component
DCS14_RS08655	COG0356	it plays a direct role in the translocation of protons across the membrane
DCS14_RS08680	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS08695	COG0747	negative chemotaxis
DCS14_RS08700	COG0601	transmembrane transport
DCS14_RS08705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS08715	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS08725	COG3048	D-serine ammonia-lyase activity
DCS14_RS08730	COG0583	DNA-binding transcription factor activity
DCS14_RS08745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS08760	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS08775	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DCS14_RS08780	COG0582	viral genome integration into host DNA
DCS14_RS08860	COG0616	signal peptide processing
DCS14_RS08865	COG0433	COG0433 Predicted ATPase
DCS14_RS08895	COG1473	amidohydrolase
DCS14_RS08900	COG1686	Belongs to the peptidase S11 family
DCS14_RS08905	COG0523	cobalamin synthesis protein
DCS14_RS08910	COG0425	Belongs to the sulfur carrier protein TusA family
DCS14_RS08920	COG0825	malonyl-CoA metabolic process
DCS14_RS08935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DCS14_RS08940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DCS14_RS08945	COG4536	flavin adenine dinucleotide binding
DCS14_RS08995	COG1522	sequence-specific DNA binding
DCS14_RS09000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DCS14_RS09005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DCS14_RS09025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS14_RS09030	COG2226	methyltransferase
DCS14_RS09050	COG0583	DNA-binding transcription factor activity
DCS14_RS09055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DCS14_RS09060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCS14_RS09065	COG0287	Prephenate dehydrogenase
DCS14_RS09100	COG2884	Cell division ATP-binding protein ftsE
DCS14_RS09110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DCS14_RS09115	COG0745	RESPONSE REGULATOR receiver
DCS14_RS09125	COG0583	DNA-binding transcription factor activity
DCS14_RS09140	COG0019	diaminopimelate decarboxylase activity
DCS14_RS09150	COG0165	Argininosuccinate lyase
DCS14_RS09155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DCS14_RS09160	COG1653	transport
DCS14_RS09165	COG1175	transmembrane transport
DCS14_RS09170	COG0395	ABC-type sugar transport system, permease component
DCS14_RS09175	COG3842	ATPase activity
DCS14_RS09185	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS09190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DCS14_RS09195	COG2086	electron transfer activity
DCS14_RS09215	COG0300	oxidoreductase activity
DCS14_RS09225	COG0697	spore germination
DCS14_RS09235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCS14_RS09255	COG1238	metal cluster binding
DCS14_RS09265	COG0583	DNA-binding transcription factor activity
DCS14_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS09315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DCS14_RS09320	COG0183	Belongs to the thiolase family
DCS14_RS09330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DCS14_RS09365	COG1309	transcriptional regulator
DCS14_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS09430	COG0625	glutathione transferase activity
DCS14_RS09435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS14_RS09445	COG0583	DNA-binding transcription factor activity
DCS14_RS09455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS14_RS09490	COG0583	DNA-binding transcription factor activity
DCS14_RS09500	COG2948	multi-organism process
DCS14_RS09515	COG3846	protein secretion by the type IV secretion system
DCS14_RS09530	COG3451	type IV secretory pathway VirB4
DCS14_RS09545	COG4962	Type ii secretion system protein e
DCS14_RS09565	COG0741	lytic transglycosylase activity
DCS14_RS09590	COG1192	Involved in chromosome partitioning
DCS14_RS09620	COG5489	Protein of unknown function (DUF736)
DCS14_RS09730	COG1396	sequence-specific DNA binding
DCS14_RS09735	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DCS14_RS09765	COG1053	succinate dehydrogenase
DCS14_RS09770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DCS14_RS09790	COG0583	DNA-binding transcription factor activity
DCS14_RS09795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS09800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCS14_RS09805	COG0473	3-isopropylmalate dehydrogenase activity
DCS14_RS09825	COG0583	DNA-binding transcription factor activity
DCS14_RS09845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS14_RS09860	COG0653	protein targeting
DCS14_RS09865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DCS14_RS09875	COG1309	transcriptional regulator
DCS14_RS09885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DCS14_RS09895	COG0494	nUDIX hydrolase
DCS14_RS09915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCS14_RS09925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCS14_RS09945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DCS14_RS09950	COG0527	aspartate kinase activity
DCS14_RS09960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCS14_RS09965	COG2890	protein-(glutamine-N5) methyltransferase activity
DCS14_RS09975	COG0542	response to heat
DCS14_RS09985	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS09990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DCS14_RS09995	COG3153	acetyltransferase
DCS14_RS10015	COG0477	Major facilitator Superfamily
DCS14_RS10025	COG0741	lytic transglycosylase activity
DCS14_RS10025	COG0739	heme binding
DCS14_RS10025	COG1196	nuclear chromosome segregation
DCS14_RS10130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS10140	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DCS14_RS10145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCS14_RS10175	COG0831	urea catabolic process
DCS14_RS10175	COG0832	Belongs to the urease beta subunit family
DCS14_RS10180	COG0804	urea catabolic process
DCS14_RS10185	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DCS14_RS10190	COG0829	nickel cation binding
DCS14_RS10200	COG0830	nickel cation binding
DCS14_RS10235	COG1396	sequence-specific DNA binding
DCS14_RS10235	COG3800	Transcriptional regulator
DCS14_RS10245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DCS14_RS10250	COG3791	Glutathione-dependent formaldehyde-activating
DCS14_RS10270	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS10280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS10295	COG1802	Transcriptional regulator
DCS14_RS10300	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS10305	COG3246	L-lysine catabolic process to acetate
DCS14_RS10320	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS10325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS14_RS10335	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS10365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS10400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS10405	COG0673	inositol 2-dehydrogenase activity
DCS14_RS10415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCS14_RS10430	COG1609	Transcriptional regulator
DCS14_RS10445	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS10450	COG1129	ABC transporter
DCS14_RS10455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS10470	COG0463	Glycosyl transferase, family 2
DCS14_RS10475	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS10500	COG0205	6-phosphofructokinase activity
DCS14_RS10505	COG1388	LysM domain
DCS14_RS10505	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS10510	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS10525	COG1070	Carbohydrate kinase
DCS14_RS10535	COG2115	Belongs to the xylose isomerase family
DCS14_RS10545	COG1011	Hydrolase
DCS14_RS10550	COG4977	sequence-specific DNA binding
DCS14_RS10555	COG3246	L-lysine catabolic process to acetate
DCS14_RS10560	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS10565	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS10590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS10625	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DCS14_RS10630	COG3257	ureidoglycine aminohydrolase activity
DCS14_RS10640	COG2351	hydroxyisourate hydrolase activity
DCS14_RS10650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DCS14_RS10660	COG0783	Belongs to the Dps family
DCS14_RS10680	COG0583	DNA-binding transcription factor activity
DCS14_RS10690	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS10695	COG4702	Belongs to the UPF0303 family
DCS14_RS10715	COG0174	glutamine synthetase
DCS14_RS10720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DCS14_RS10745	COG0523	cobalamin synthesis protein
DCS14_RS10755	COG1846	Transcriptional regulator
DCS14_RS10765	COG1609	Transcriptional regulator
DCS14_RS10770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DCS14_RS10775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DCS14_RS10780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DCS14_RS10780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DCS14_RS10810	COG5001	Diguanylate cyclase
DCS14_RS10845	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS10860	COG2249	NAD(P)H dehydrogenase (quinone) activity
DCS14_RS10870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DCS14_RS10880	COG2223	nitrite transmembrane transporter activity
DCS14_RS10890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS10910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS10910	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS10955	COG0531	amino acid
DCS14_RS10990	COG3842	ATPase activity
DCS14_RS11000	COG0583	DNA-binding transcription factor activity
DCS14_RS11005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DCS14_RS11010	COG3842	ATPase activity
DCS14_RS11015	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS11020	COG1177	transmembrane transport
DCS14_RS11025	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS11040	COG1609	Transcriptional regulator
DCS14_RS11055	COG1024	Enoyl-CoA hydratase
DCS14_RS11060	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS11065	COG1653	transport
DCS14_RS11075	COG0395	ABC-type sugar transport system, permease component
DCS14_RS11080	COG3842	ATPase activity
DCS14_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS11120	COG2072	flavoprotein involved in K transport
DCS14_RS11165	COG0071	Belongs to the small heat shock protein (HSP20) family
DCS14_RS11175	COG2267	carboxylic ester hydrolase activity
DCS14_RS11185	COG0070	glutamate synthase
DCS14_RS11185	COG0069	glutamate synthase activity
DCS14_RS11185	COG0067	glutamate synthase
DCS14_RS11200	COG2951	lytic endotransglycosylase activity
DCS14_RS11205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCS14_RS11210	COG0778	Nitroreductase
DCS14_RS11215	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCS14_RS11235	COG0330	HflC and HflK could
DCS14_RS11245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DCS14_RS11250	COG0737	Belongs to the 5'-nucleotidase family
DCS14_RS11260	COG5310	Homospermidine synthase
DCS14_RS11285	COG2204	response regulator
DCS14_RS11290	COG3108	Peptidase M15
DCS14_RS11295	COG0800	Aldolase
DCS14_RS11300	COG5632	N-Acetylmuramoyl-L-alanine amidase
DCS14_RS11300	COG3409	Peptidoglycan-binding domain 1 protein
DCS14_RS11305	COG1054	Belongs to the UPF0176 family
DCS14_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS11350	COG0583	DNA-binding transcription factor activity
DCS14_RS11360	COG0154	amidase activity
DCS14_RS11405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DCS14_RS11415	COG2020	methyltransferase activity
DCS14_RS11430	COG2814	Major facilitator Superfamily
DCS14_RS11440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DCS14_RS11445	COG5443	negative regulation of bacterial-type flagellum assembly
DCS14_RS11450	COG5442	Flagellar protein FlaF
DCS14_RS11505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCS14_RS11510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCS14_RS11520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCS14_RS11525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCS14_RS11530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DCS14_RS11535	COG1338	Plays a role in the flagellum-specific transport system
DCS14_RS11545	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DCS14_RS11555	COG1706	bacterial-type flagellum-dependent cell motility
DCS14_RS11560	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
DCS14_RS11565	COG4786	Flagellar basal body rod
DCS14_RS11570	COG1677	Flagellar hook-basal body complex protein FliE
DCS14_RS11575	COG1558	bacterial-type flagellum-dependent cell motility
DCS14_RS11580	COG1815	bacterial-type flagellum-dependent cell motility
DCS14_RS11590	COG1157	protein secretion by the type III secretion system
DCS14_RS11595	COG4786	Flagellar basal body rod
DCS14_RS11605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DCS14_RS11610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCS14_RS11615	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCS14_RS11620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DCS14_RS11625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DCS14_RS11640	COG2771	luxR family
DCS14_RS11655	COG1309	transcriptional regulator
DCS14_RS11660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DCS14_RS11665	COG3842	ATPase activity
DCS14_RS11675	COG1177	transmembrane transport
DCS14_RS11720	COG1609	Transcriptional regulator
DCS14_RS11725	COG0463	Glycosyl transferase, family 2
DCS14_RS11725	COG1216	Glycosyl transferase, family 2
DCS14_RS11745	COG1129	ABC transporter
DCS14_RS11750	COG4211	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS11755	COG0673	inositol 2-dehydrogenase activity
DCS14_RS11760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS11765	COG3962	Belongs to the TPP enzyme family
DCS14_RS11770	COG1082	Xylose isomerase domain protein TIM barrel
DCS14_RS11780	COG3718	enzyme involved in inositol metabolism
DCS14_RS11785	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCS14_RS11800	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
DCS14_RS11820	COG2197	response regulator
DCS14_RS11840	COG0747	negative chemotaxis
DCS14_RS11865	COG0747	negative chemotaxis
DCS14_RS11880	COG3454	Phosphonate metabolism
DCS14_RS11885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DCS14_RS11890	COG3639	organic phosphonate transmembrane transporter activity
DCS14_RS11905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DCS14_RS11915	COG0786	glutamate:sodium symporter activity
DCS14_RS11925	COG4778	phosphonate C-P lyase system protein PhnL
DCS14_RS11930	COG4107	phosphonate C-P lyase system protein PhnK
DCS14_RS11935	COG3627	carbon phosphorus lyase activity
DCS14_RS11945	COG1598	PFAM Uncharacterised protein family UPF0150
DCS14_RS11950	COG3626	phosphonate metabolism
DCS14_RS11955	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DCS14_RS11960	COG3624	Phosphonate C-P lyase system protein PhnG
DCS14_RS11965	COG2188	Transcriptional regulator
DCS14_RS11970	COG3307	-O-antigen
DCS14_RS11975	COG1596	polysaccharide export
DCS14_RS11990	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS12005	COG2273	Hydrolase Family 16
DCS14_RS12035	COG0438	transferase activity, transferring glycosyl groups
DCS14_RS12040	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS12045	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS12050	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS12055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCS14_RS12060	COG0489	protein tyrosine kinase activity
DCS14_RS12060	COG3206	protein involved in exopolysaccharide biosynthesis
DCS14_RS12085	COG0482	sulfurtransferase activity
DCS14_RS12100	COG1733	regulation of RNA biosynthetic process
DCS14_RS12115	COG2201	protein-glutamate methylesterase activity
DCS14_RS12160	COG0435	Glutathione S-transferase
DCS14_RS12165	COG0494	nUDIX hydrolase
DCS14_RS12190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCS14_RS12200	COG3180	Ammonia monooxygenase
DCS14_RS12225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DCS14_RS12230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DCS14_RS12230	COG0512	Glutamine amidotransferase of anthranilate synthase
DCS14_RS12235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS12245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DCS14_RS12250	COG2814	Major facilitator Superfamily
DCS14_RS12255	COG0583	DNA-binding transcription factor activity
DCS14_RS12260	COG2962	Rard protein
DCS14_RS12265	COG4993	Dehydrogenase
DCS14_RS12280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCS14_RS12295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DCS14_RS12315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DCS14_RS12350	COG1435	thymidine kinase activity
DCS14_RS12360	COG4176	ABC-type proline glycine betaine transport system permease component
DCS14_RS12365	COG3448	diguanylate cyclase activity
DCS14_RS12365	COG4175	Glycine betaine
DCS14_RS12385	COG5507	3-demethylubiquinone-9 3-methyltransferase
DCS14_RS12390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DCS14_RS12410	COG1278	Cold shock
DCS14_RS12430	COG0714	Associated with various cellular activities
DCS14_RS12445	COG0617	tRNA 3'-terminal CCA addition
DCS14_RS12460	COG0513	Belongs to the DEAD box helicase family
DCS14_RS12475	COG0408	coproporphyrinogen oxidase activity
DCS14_RS12495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DCS14_RS12505	COG1132	(ABC) transporter
DCS14_RS12510	COG1132	(ABC) transporter
DCS14_RS12515	COG1132	(ABC) transporter
DCS14_RS12535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DCS14_RS12535	COG2857	Cytochrome c1
DCS14_RS12540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCS14_RS12565	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DCS14_RS12575	COG0012	GTP binding
DCS14_RS12580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCS14_RS12590	COG0193	aminoacyl-tRNA hydrolase activity
DCS14_RS12595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DCS14_RS12615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DCS14_RS12630	COG1496	oxidoreductase activity
DCS14_RS12640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCS14_RS12655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCS14_RS12665	COG1464	Belongs to the NlpA lipoprotein family
DCS14_RS12670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCS14_RS12675	COG2011	ABC-type metal ion transport system permease component
DCS14_RS12680	COG2205	protein histidine kinase activity
DCS14_RS12690	COG0745	RESPONSE REGULATOR receiver
DCS14_RS12695	COG1846	Transcriptional regulator
DCS14_RS12700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS12710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS14_RS12720	COG1278	Cold shock
DCS14_RS12730	COG1278	Cold shock
DCS14_RS12745	COG3791	Glutathione-dependent formaldehyde-activating
DCS14_RS12755	COG2264	protein methyltransferase activity
DCS14_RS12760	COG1396	sequence-specific DNA binding
DCS14_RS12800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DCS14_RS12810	COG1522	sequence-specific DNA binding
DCS14_RS12835	COG0556	nucleotide-excision repair
DCS14_RS12900	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS12925	COG1253	flavin adenine dinucleotide binding
DCS14_RS12965	COG2133	pyrroloquinoline quinone binding
DCS14_RS12970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS12980	COG1215	transferase activity, transferring glycosyl groups
DCS14_RS12995	COG1522	sequence-specific DNA binding
DCS14_RS13000	COG0492	ferredoxin-NADP+ reductase activity
DCS14_RS13005	COG0583	DNA-binding transcription factor activity
DCS14_RS13020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DCS14_RS13025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCS14_RS13040	COG0436	Aminotransferase
DCS14_RS13045	COG3300	MHYT domain
DCS14_RS13045	COG5001	Diguanylate cyclase
DCS14_RS13055	COG0625	glutathione transferase activity
DCS14_RS13060	COG1278	Cold shock
DCS14_RS13070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DCS14_RS13080	COG0456	acetyltransferase
DCS14_RS13105	COG0456	acetyltransferase
DCS14_RS13105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DCS14_RS13115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCS14_RS13120	COG0640	Transcriptional regulator
DCS14_RS13125	COG2814	Major facilitator Superfamily
DCS14_RS13135	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS13155	COG2321	neutral zinc metallopeptidase
DCS14_RS13160	COG4989	oxidoreductase activity
DCS14_RS13175	COG0505	Belongs to the CarA family
DCS14_RS13190	COG1473	amidohydrolase
DCS14_RS13210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCS14_RS13225	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS13245	COG1309	transcriptional regulator
DCS14_RS13280	COG3685	Protein conserved in bacteria
DCS14_RS13295	COG2862	Uncharacterized protein family, UPF0114
DCS14_RS13305	COG2983	Belongs to the UPF0260 family
DCS14_RS13315	COG2968	Membrane
DCS14_RS13335	COG1177	transmembrane transport
DCS14_RS13340	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS13345	COG3842	ATPase activity
DCS14_RS13370	COG2207	Transcriptional regulator
DCS14_RS13380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS13385	COG3474	cytochrome
DCS14_RS13430	COG0651	ATP synthesis coupled electron transport
DCS14_RS13435	COG1006	Multisubunit Na H antiporter MnhC subunit
DCS14_RS13440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCS14_RS13440	COG2111	Na H antiporter
DCS14_RS13455	COG2212	antiporter activity
DCS14_RS13460	COG1863	multisubunit Na H antiporter MnhE subunit
DCS14_RS13480	COG2235	arginine
DCS14_RS13520	COG2814	Major facilitator Superfamily
DCS14_RS13530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS13540	COG0583	DNA-binding transcription factor activity
DCS14_RS13550	COG1917	Cupin 2, conserved barrel domain protein
DCS14_RS13570	COG1129	ABC transporter
DCS14_RS13580	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DCS14_RS13590	COG2124	cytochrome p450
DCS14_RS13610	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCS14_RS13615	COG1082	Xylose isomerase domain protein TIM barrel
DCS14_RS13620	COG2721	sulfolactate sulfo-lyase activity
DCS14_RS13625	COG2721	sulfolactate sulfo-lyase activity
DCS14_RS13635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS13640	COG0601	transmembrane transport
DCS14_RS13645	COG0747	negative chemotaxis
DCS14_RS13650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS14_RS13660	COG0626	cystathionine gamma-synthase activity
DCS14_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS13670	COG4597	amino acid ABC transporter
DCS14_RS13675	COG0765	amino acid transport
DCS14_RS13680	COG1126	abc transporter atp-binding protein
DCS14_RS13695	COG0583	DNA-binding transcription factor activity
DCS14_RS13700	COG2814	Major facilitator Superfamily
DCS14_RS13710	COG0590	tRNA wobble adenosine to inosine editing
DCS14_RS13735	COG0601	transmembrane transport
DCS14_RS13750	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS13765	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS13770	COG3284	Transcriptional regulator
DCS14_RS13785	COG3284	Transcriptional regulator
DCS14_RS13795	COG4459	periplasmic nitrate reductase
DCS14_RS13820	COG3005	denitrification pathway
DCS14_RS13830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DCS14_RS13860	COG1845	cytochrome c oxidase, subunit III
DCS14_RS13875	COG3256	nitric oxide reductase
DCS14_RS13880	COG0714	Associated with various cellular activities
DCS14_RS13890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DCS14_RS13910	COG3707	response regulator
DCS14_RS13915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCS14_RS13925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DCS14_RS13935	COG0243	molybdopterin cofactor binding
DCS14_RS13950	COG0463	Glycosyl transferase, family 2
DCS14_RS13990	COG2197	response regulator
DCS14_RS13995	COG1280	lysine exporter protein (LysE YggA)
DCS14_RS14010	COG0583	DNA-binding transcription factor activity
DCS14_RS14020	COG1902	pentaerythritol trinitrate reductase activity
DCS14_RS14035	COG0673	inositol 2-dehydrogenase activity
DCS14_RS14040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS14045	COG4597	amino acid ABC transporter
DCS14_RS14050	COG0765	amino acid transport
DCS14_RS14075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCS14_RS14080	COG4208	sulfate ABC transporter
DCS14_RS14085	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DCS14_RS14090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DCS14_RS14100	COG4953	penicillin-binding protein 1C
DCS14_RS14110	COG0729	surface antigen
DCS14_RS14120	COG0747	negative chemotaxis
DCS14_RS14125	COG0601	transmembrane transport
DCS14_RS14130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS14145	COG0493	'glutamate synthase
DCS14_RS14165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DCS14_RS14175	COG1309	transcriptional regulator
DCS14_RS14180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCS14_RS14200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS14205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS14235	COG0028	Belongs to the TPP enzyme family
DCS14_RS14245	COG2267	carboxylic ester hydrolase activity
DCS14_RS14250	COG1131	(ABC) transporter
DCS14_RS14255	COG0842	Transport permease protein
DCS14_RS14310	COG1720	tRNA m6t6A37 methyltransferase activity
DCS14_RS14335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCS14_RS14370	COG0697	spore germination
DCS14_RS14375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DCS14_RS14400	COG0626	cystathionine gamma-synthase activity
DCS14_RS14405	COG2001	Belongs to the MraZ family
DCS14_RS14410	COG0275	rRNA processing
DCS14_RS14425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DCS14_RS14435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCS14_RS14440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCS14_RS14450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCS14_RS14455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DCS14_RS14460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DCS14_RS14465	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCS14_RS14470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DCS14_RS14475	COG0849	cell division
DCS14_RS14480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCS14_RS14490	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DCS14_RS14505	COG2176	DNA-directed DNA polymerase activity
DCS14_RS14520	COG0006	proline dipeptidase activity
DCS14_RS14520	COG0006	proline dipeptidase activity
DCS14_RS14525	COG2264	protein methyltransferase activity
DCS14_RS14530	COG1999	signal sequence binding
DCS14_RS14570	COG0210	DNA helicase
DCS14_RS14595	COG0277	FAD linked oxidase domain protein
DCS14_RS14640	COG2814	Major facilitator Superfamily
DCS14_RS14675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS14700	COG0330	HflC and HflK could
DCS14_RS14705	COG0330	HflC and HflK could
DCS14_RS14715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCS14_RS14735	COG3830	Belongs to the UPF0237 family
DCS14_RS14735	COG0560	Phosphoserine phosphatase
DCS14_RS14740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DCS14_RS14770	COG0028	Belongs to the TPP enzyme family
DCS14_RS14815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCS14_RS14830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DCS14_RS14835	COG3158	transport of potassium into the cell
DCS14_RS14850	COG1309	transcriptional regulator
DCS14_RS14855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DCS14_RS14885	COG0577	efflux transmembrane transporter activity
DCS14_RS14885	COG1136	(ABC) transporter
DCS14_RS14890	COG1136	(ABC) transporter
DCS14_RS14890	COG0577	efflux transmembrane transporter activity
DCS14_RS14900	COG0384	phenazine biosynthesis protein PhzF
DCS14_RS14910	COG2066	Belongs to the glutaminase family
DCS14_RS14915	COG0628	permease
DCS14_RS14930	COG1959	2 iron, 2 sulfur cluster binding
DCS14_RS14935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCS14_RS14940	COG4208	sulfate ABC transporter
DCS14_RS14950	COG4150	thiosulfate binding
DCS14_RS14955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DCS14_RS14960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DCS14_RS14965	COG1797	cobyrinic acid a,c-diamide synthase activity
DCS14_RS14975	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DCS14_RS15035	COG3214	Protein conserved in bacteria
DCS14_RS15040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS14_RS15045	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS14_RS15050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS14_RS15055	COG0649	NAD binding
DCS14_RS15060	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DCS14_RS15065	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DCS14_RS15070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCS14_RS15070	COG3743	rRNA binding
DCS14_RS15080	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DCS14_RS15085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS14_RS15095	COG0713	ATP synthesis coupled electron transport
DCS14_RS15110	COG1007	ATP synthesis coupled electron transport
DCS14_RS15125	COG0346	lactoylglutathione lyase activity
DCS14_RS15135	COG0442	prolyl-tRNA aminoacylation
DCS14_RS15145	COG1136	(ABC) transporter
DCS14_RS15150	COG0321	lipoyl(octanoyl) transferase activity
DCS14_RS15175	COG0789	Transcriptional regulator
DCS14_RS15180	COG2239	Acts as a magnesium transporter
DCS14_RS15205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DCS14_RS15230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DCS14_RS15260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCS14_RS15295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS15295	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS15305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS15310	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DCS14_RS15310	COG3264	Mechanosensitive ion channel
DCS14_RS15335	COG1088	dTDP-glucose 4,6-dehydratase activity
DCS14_RS15375	COG0583	DNA-binding transcription factor activity
DCS14_RS15400	COG1410	methionine synthase
DCS14_RS15400	COG0646	methionine synthase
DCS14_RS15420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCS14_RS15425	COG3932	Exopolysaccharide synthesis, ExoD
DCS14_RS15445	COG5012	cobalamin binding
DCS14_RS15450	COG5598	trimethylamine methyltransferase
DCS14_RS15460	COG2186	Transcriptional regulator
DCS14_RS15465	COG2807	transmembrane transport
DCS14_RS15470	COG2081	HI0933 family
DCS14_RS15480	COG2304	oxidoreductase activity
DCS14_RS15500	COG0646	methionine synthase
DCS14_RS15500	COG1410	methionine synthase
DCS14_RS15505	COG3665	Urea carboxylase-associated protein
DCS14_RS15525	COG0006	proline dipeptidase activity
DCS14_RS15540	COG0251	oxidation-reduction process
DCS14_RS15545	COG5598	trimethylamine methyltransferase
DCS14_RS15585	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS15590	COG1492	cobalamin metabolic process
DCS14_RS15620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS15625	COG0601	transmembrane transport
DCS14_RS15630	COG0747	negative chemotaxis
DCS14_RS15635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS14_RS15665	COG0243	molybdopterin cofactor binding
DCS14_RS15670	COG0437	4 iron, 4 sulfur cluster binding
DCS14_RS15680	COG1560	Kdo2-lipid A biosynthetic process
DCS14_RS15690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCS14_RS15695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCS14_RS15700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCS14_RS15725	COG1858	cytochrome C peroxidase
DCS14_RS15730	COG1522	sequence-specific DNA binding
DCS14_RS15770	COG3720	iron ion transport
DCS14_RS15775	COG4558	Periplasmic binding protein
DCS14_RS15780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS15785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DCS14_RS15790	COG2514	catechol 2,3-dioxygenase activity
DCS14_RS15795	COG0037	tRNA processing
DCS14_RS15800	COG2814	Major facilitator Superfamily
DCS14_RS15805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DCS14_RS15815	COG2226	methyltransferase
DCS14_RS15825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCS14_RS15840	COG0047	phosphoribosylformylglycinamidine synthase activity
DCS14_RS15850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCS14_RS15855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DCS14_RS15875	COG1959	2 iron, 2 sulfur cluster binding
DCS14_RS15885	COG2733	membrane
DCS14_RS15940	COG2832	Protein of unknown function (DUF454)
DCS14_RS15975	COG2948	multi-organism process
DCS14_RS15990	COG3846	protein secretion by the type IV secretion system
DCS14_RS16005	COG3451	type IV secretory pathway VirB4
DCS14_RS16020	COG4962	Type ii secretion system protein e
DCS14_RS16050	COG3436	PFAM IS66 Orf2 family protein
DCS14_RS16055	COG2433	Pfam Transposase IS66
DCS14_RS16060	COG0741	lytic transglycosylase activity
DCS14_RS16095	COG3608	succinylglutamate desuccinylase aspartoacylase
DCS14_RS16100	COG1126	abc transporter atp-binding protein
DCS14_RS16105	COG4597	amino acid ABC transporter
DCS14_RS16110	COG0765	amino acid transport
DCS14_RS16115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS16135	COG2197	response regulator
DCS14_RS16140	COG3916	Acyl-homoserine-lactone synthase
DCS14_RS16145	COG5489	Protein of unknown function (DUF736)
DCS14_RS16180	COG1733	regulation of RNA biosynthetic process
DCS14_RS16195	COG0583	DNA-binding transcription factor activity
DCS14_RS16205	COG0456	acetyltransferase
DCS14_RS16215	COG3852	Histidine kinase
DCS14_RS16265	COG0573	inorganic phosphate transmembrane transporter activity
DCS14_RS16270	COG0581	inorganic phosphate transmembrane transporter activity
DCS14_RS16275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCS14_RS16280	COG0704	Plays a role in the regulation of phosphate uptake
DCS14_RS16285	COG0745	RESPONSE REGULATOR receiver
DCS14_RS16305	COG0431	NADPH-dependent FMN reductase
DCS14_RS16310	COG1393	Belongs to the ArsC family
DCS14_RS16315	COG0798	PFAM Bile acid sodium symporter
DCS14_RS16330	COG0640	Transcriptional regulator
DCS14_RS16345	COG1793	dna ligase
DCS14_RS16385	COG2217	Heavy metal translocating P-type atpase
DCS14_RS16415	COG1136	(ABC) transporter
DCS14_RS16450	COG0071	Belongs to the small heat shock protein (HSP20) family
DCS14_RS16505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DCS14_RS16545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCS14_RS16545	COG0045	succinate-CoA ligase (ADP-forming) activity
DCS14_RS16545	COG1042	CoA-binding domain protein
DCS14_RS16555	COG2217	Heavy metal translocating P-type atpase
DCS14_RS16575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DCS14_RS16600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DCS14_RS16615	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DCS14_RS16630	COG2205	protein histidine kinase activity
DCS14_RS16645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DCS14_RS16660	COG2235	arginine
DCS14_RS16690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DCS14_RS16705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DCS14_RS16710	COG2202	Pas domain
DCS14_RS16710	COG2205	protein histidine kinase activity
DCS14_RS16725	COG1573	uracil-dna glycosylase
DCS14_RS16730	COG1522	sequence-specific DNA binding
DCS14_RS16740	COG2084	Dehydrogenase
DCS14_RS16765	COG0746	molybdenum cofactor guanylyltransferase activity
DCS14_RS16780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCS14_RS16800	COG1846	Transcriptional regulator
DCS14_RS16815	COG2989	Protein conserved in bacteria
DCS14_RS16830	COG0546	phosphoglycolate phosphatase activity
DCS14_RS16835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DCS14_RS16850	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DCS14_RS16865	COG2199	diguanylate cyclase activity
DCS14_RS16875	COG3384	dioxygenase
DCS14_RS16880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DCS14_RS16920	COG0740	serine-type endopeptidase activity
DCS14_RS16930	COG0640	Transcriptional regulator
DCS14_RS16935	COG1132	(ABC) transporter
DCS14_RS16940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCS14_RS16950	COG0280	phosphate acetyltransferase
DCS14_RS16950	COG0281	malic enzyme
DCS14_RS16970	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS16975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DCS14_RS16980	COG1127	ABC transporter
DCS14_RS16990	COG3218	ABC-type transport auxiliary lipoprotein component
DCS14_RS16990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DCS14_RS17005	COG0633	Ferredoxin
DCS14_RS17010	COG0492	ferredoxin-NADP+ reductase activity
DCS14_RS17020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DCS14_RS17030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DCS14_RS17045	COG0784	Response regulator, receiver
DCS14_RS17065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DCS14_RS17070	COG2814	Major facilitator Superfamily
DCS14_RS17085	COG0557	exoribonuclease II activity
DCS14_RS17090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCS14_RS17100	COG0758	DNA mediated transformation
DCS14_RS17105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DCS14_RS17110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCS14_RS17115	COG0540	Belongs to the ATCase OTCase family
DCS14_RS17120	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS17130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DCS14_RS17135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DCS14_RS17145	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCS14_RS17150	COG0154	amidase activity
DCS14_RS17160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DCS14_RS17170	COG1760	l-serine dehydratase
DCS14_RS17185	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DCS14_RS17200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DCS14_RS17210	COG3706	GGDEF domain
DCS14_RS17235	COG0537	adenosine 5'-monophosphoramidase activity
DCS14_RS17250	COG0584	glycerophosphoryl diester phosphodiesterase
DCS14_RS17270	COG0052	Belongs to the universal ribosomal protein uS2 family
DCS14_RS17275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCS14_RS17280	COG0528	UMP kinase activity
DCS14_RS17285	COG0233	cytoplasmic translational termination
DCS14_RS17290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCS14_RS17300	COG0750	zinc metalloprotease
DCS14_RS17305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DCS14_RS17310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DCS14_RS17315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DCS14_RS17320	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DCS14_RS17325	COG3494	Protein of unknown function (DUF1009)
DCS14_RS17330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DCS14_RS17335	COG0372	Belongs to the citrate synthase family
DCS14_RS17340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCS14_RS17350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCS14_RS17355	COG0303	'Molybdopterin
DCS14_RS17360	COG0315	cyclic pyranopterin monophosphate synthase activity
DCS14_RS17365	COG0134	indole-3-glycerol-phosphate synthase activity
DCS14_RS17370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DCS14_RS17380	COG0149	triose-phosphate isomerase activity
DCS14_RS17395	COG0504	CTP synthase activity
DCS14_RS17410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DCS14_RS17425	COG0148	phosphopyruvate hydratase activity
DCS14_RS17430	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DCS14_RS17435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DCS14_RS17440	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS14_RS17440	COG0022	dehydrogenase e1 component
DCS14_RS17445	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS14_RS17455	COG0456	acetyltransferase
DCS14_RS17460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCS14_RS17470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DCS14_RS17475	COG2867	negative regulation of translational initiation
DCS14_RS17485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DCS14_RS17485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DCS14_RS17495	COG3852	Histidine kinase
DCS14_RS17500	COG2204	response regulator
DCS14_RS17505	COG5000	phosphorelay sensor kinase activity
DCS14_RS17510	COG2204	response regulator
DCS14_RS17515	COG0569	domain protein
DCS14_RS17520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS17525	COG1923	regulation of RNA biosynthetic process
DCS14_RS17530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DCS14_RS17535	COG3956	TIGRFAM MazG family protein
DCS14_RS17540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCS14_RS17550	COG0546	phosphoglycolate phosphatase activity
DCS14_RS17560	COG0174	glutamine synthetase
DCS14_RS17570	COG0346	lactoylglutathione lyase activity
DCS14_RS17585	COG0174	glutamine synthetase
DCS14_RS17590	COG0347	Belongs to the P(II) protein family
DCS14_RS17595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DCS14_RS17595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DCS14_RS17610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DCS14_RS17620	COG1794	racemase activity, acting on amino acids and derivatives
DCS14_RS17635	COG0671	phosphoesterase, PA-phosphatase related
DCS14_RS17640	COG0629	single-stranded DNA binding
DCS14_RS17655	COG2095	MarC family integral membrane protein
DCS14_RS17660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCS14_RS17665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DCS14_RS17685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DCS14_RS17690	COG0343	queuine tRNA-ribosyltransferase activity
DCS14_RS17725	COG2308	Evidence 4 Homologs of previously reported genes of
DCS14_RS17785	COG0785	Cytochrome C biogenesis protein
DCS14_RS17790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DCS14_RS17795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DCS14_RS17805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DCS14_RS17815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DCS14_RS17830	COG4166	transmembrane transport
DCS14_RS17845	COG0679	Auxin Efflux Carrier
DCS14_RS17850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCS14_RS17855	COG1183	phosphatidylcholine synthase activity
DCS14_RS17865	COG3845	ABC transporter
DCS14_RS17870	COG4603	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS17875	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS17885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCS14_RS17890	COG0861	Integral membrane protein TerC family
DCS14_RS17905	COG0739	heme binding
DCS14_RS18075	COG2814	Major facilitator Superfamily
DCS14_RS18100	COG1686	Belongs to the peptidase S11 family
DCS14_RS18105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DCS14_RS18120	COG0084	hydrolase, TatD family'
DCS14_RS18125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DCS14_RS18125	COG0321	lipoyl(octanoyl) transferase activity
DCS14_RS18135	COG2826	transposase and inactivated derivatives, IS30 family
DCS14_RS18140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DCS14_RS18145	COG4638	Rieske (2fe-2S)
DCS14_RS18150	COG0583	DNA-binding transcription factor activity
DCS14_RS18155	COG0747	negative chemotaxis
DCS14_RS18170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS18175	COG0601	transmembrane transport
DCS14_RS18180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS18200	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS18200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS18205	COG4311	Sarcosine oxidase, delta subunit
DCS14_RS18210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS18235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DCS14_RS18240	COG0667	Aldo Keto reductase
DCS14_RS18250	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS18285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS14_RS18285	COG3453	Protein conserved in bacteria
DCS14_RS18290	COG3453	Protein conserved in bacteria
DCS14_RS18290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS14_RS18295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DCS14_RS18305	COG0203	ribosomal protein L17
DCS14_RS18310	COG0202	RNA polymerase activity
DCS14_RS18315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DCS14_RS18320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCS14_RS18325	COG0563	adenylate kinase activity
DCS14_RS18335	COG0200	Binds to the 23S rRNA
DCS14_RS18340	COG1841	ribosomal large subunit assembly
DCS14_RS18345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DCS14_RS18350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DCS14_RS18355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DCS14_RS18360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DCS14_RS18365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DCS14_RS18370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCS14_RS18375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DCS14_RS18380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCS14_RS18385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCS14_RS18390	COG0255	Belongs to the universal ribosomal protein uL29 family
DCS14_RS18395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCS14_RS18400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCS14_RS18405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCS14_RS18410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DCS14_RS18415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DCS14_RS18420	COG0089	rRNA binding
DCS14_RS18425	COG0088	Forms part of the polypeptide exit tunnel
DCS14_RS18430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCS14_RS18435	COG0051	transcription antitermination factor activity, RNA binding
DCS14_RS18440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCS14_RS18445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCS14_RS18450	COG0049	tRNA binding
DCS14_RS18455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DCS14_RS18465	COG0531	amino acid
DCS14_RS18470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCS14_RS18475	COG0085	RNA polymerase activity
DCS14_RS18480	COG0222	ribosome binding
DCS14_RS18485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DCS14_RS18490	COG0081	regulation of translation
DCS14_RS18495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DCS14_RS18505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCS14_RS18525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCS14_RS18540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCS14_RS18550	COG2084	Dehydrogenase
DCS14_RS18555	COG3622	Belongs to the hyi family
DCS14_RS18560	COG3960	tartronate-semialdehyde synthase activity
DCS14_RS18565	COG1414	Transcriptional regulator
DCS14_RS18575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DCS14_RS18585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCS14_RS18590	COG0513	Belongs to the DEAD box helicase family
DCS14_RS18595	COG2885	chlorophyll binding
DCS14_RS18620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DCS14_RS18625	COG0860	N-Acetylmuramoyl-L-alanine amidase
DCS14_RS18630	COG1530	ribonuclease E activity
DCS14_RS18635	COG4957	zinc ion binding
DCS14_RS18645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DCS14_RS18655	COG0737	Belongs to the 5'-nucleotidase family
DCS14_RS18660	COG1522	sequence-specific DNA binding
DCS14_RS18665	COG0686	Belongs to the AlaDH PNT family
DCS14_RS18670	COG2885	chlorophyll binding
DCS14_RS18670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DCS14_RS18690	COG2897	thiosulfate sulfurtransferase activity
DCS14_RS18695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCS14_RS18700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DCS14_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS18715	COG0513	Belongs to the DEAD box helicase family
DCS14_RS18745	COG3106	COG3106 Predicted ATPase
DCS14_RS18750	COG3768	UPF0283 membrane protein
DCS14_RS18765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DCS14_RS18765	COG0475	glutathione-regulated potassium exporter activity
DCS14_RS18780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCS14_RS18790	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS18810	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DCS14_RS18820	COG1671	Belongs to the UPF0178 family
DCS14_RS18835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DCS14_RS18840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS18845	COG0509	glycine decarboxylation via glycine cleavage system
DCS14_RS18850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCS14_RS18850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCS14_RS18860	COG0187	DNA topoisomerase II activity
DCS14_RS18875	COG2301	Belongs to the HpcH HpaI aldolase family
DCS14_RS18880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS14_RS18885	COG0778	Nitroreductase
DCS14_RS18895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCS14_RS18905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DCS14_RS18910	COG0583	DNA-binding transcription factor activity
DCS14_RS18920	COG0302	gtp cyclohydrolase
DCS14_RS18925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DCS14_RS18930	COG1752	Esterase of the alpha-beta hydrolase superfamily
DCS14_RS18935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DCS14_RS18940	COG1494	fructose-1,6-bisphosphatase
DCS14_RS18950	COG0436	Aminotransferase
DCS14_RS18960	COG3243	poly(R)-hydroxyalkanoic acid synthase
DCS14_RS19020	COG1802	Transcriptional regulator
DCS14_RS19035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCS14_RS19045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS19050	COG1802	Transcriptional regulator
DCS14_RS19055	COG2824	Alkylphosphonate utilization operon protein PhnA
DCS14_RS19065	COG0024	Methionine aminopeptidase
DCS14_RS19070	COG2003	Belongs to the UPF0758 family
DCS14_RS19130	COG2197	response regulator
DCS14_RS19150	COG3846	protein secretion by the type IV secretion system
DCS14_RS19165	COG2948	multi-organism process
DCS14_RS19185	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCS14_RS19195	COG0438	transferase activity, transferring glycosyl groups
DCS14_RS19225	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DCS14_RS19230	COG0519	Catalyzes the synthesis of GMP from XMP
DCS14_RS19250	COG1862	Preprotein translocase
DCS14_RS19265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DCS14_RS19270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DCS14_RS19275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DCS14_RS19280	COG0805	protein transport
DCS14_RS19285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCS14_RS19290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCS14_RS19300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCS14_RS19305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DCS14_RS19320	COG0018	arginyl-trna synthetase
DCS14_RS19325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DCS14_RS19345	COG2233	PERMEase
DCS14_RS19365	COG0525	valine-tRNA ligase activity
DCS14_RS19380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DCS14_RS19400	COG1473	amidohydrolase
DCS14_RS19425	COG0436	Aminotransferase
DCS14_RS19440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DCS14_RS19445	COG0511	ligase activity, forming carbon-carbon bonds
DCS14_RS19455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DCS14_RS19480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCS14_RS19485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DCS14_RS19495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCS14_RS19500	COG3811	Belongs to the UPF0386 family
DCS14_RS19505	COG0516	GMP reductase activity
DCS14_RS19505	COG0517	IMP dehydrogenase activity
DCS14_RS19550	COG1024	Enoyl-CoA hydratase
DCS14_RS19570	COG1278	Cold shock
DCS14_RS19575	COG0346	lactoylglutathione lyase activity
DCS14_RS19585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCS14_RS19590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCS14_RS19605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DCS14_RS19670	COG1058	Belongs to the CinA family
DCS14_RS19670	COG1546	Belongs to the CinA family
DCS14_RS19680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DCS14_RS19690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCS14_RS19695	COG2827	Endonuclease containing a URI domain
DCS14_RS19700	COG2827	Endonuclease containing a URI domain
DCS14_RS19705	COG1607	acyl-coa hydrolase
DCS14_RS19715	COG2855	membrane
DCS14_RS19720	COG0583	DNA-binding transcription factor activity
DCS14_RS19745	COG0596	Alpha beta hydrolase
DCS14_RS19745	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS14_RS19780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DCS14_RS19785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DCS14_RS19785	COG3608	succinylglutamate desuccinylase aspartoacylase
DCS14_RS19805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS14_RS19815	COG3191	aminopeptidase activity
DCS14_RS19830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DCS14_RS19835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DCS14_RS19845	COG1733	regulation of RNA biosynthetic process
DCS14_RS19860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DCS14_RS19870	COG0538	isocitrate dehydrogenase activity
DCS14_RS19880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCS14_RS19885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCS14_RS19890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS19895	COG2313	pseudouridylate synthase activity
DCS14_RS19910	COG0316	Belongs to the HesB IscA family
DCS14_RS19915	COG2151	metal-sulfur cluster biosynthetic enzyme
DCS14_RS19920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DCS14_RS19925	COG0719	Fe-S assembly protein
DCS14_RS19930	COG0396	ATPase activity
DCS14_RS19935	COG0719	Fe-S assembly protein
DCS14_RS19940	COG1104	cysteine desulfurase activity
DCS14_RS19945	COG2945	thiolester hydrolase activity
DCS14_RS19965	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DCS14_RS19970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DCS14_RS19980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DCS14_RS19985	COG0739	heme binding
DCS14_RS20000	COG0720	synthase
DCS14_RS20010	COG5001	Diguanylate cyclase
DCS14_RS20030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DCS14_RS20045	COG0156	8-amino-7-oxononanoate synthase activity
DCS14_RS20055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCS14_RS20060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCS14_RS20080	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS20085	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS20090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS20095	COG0601	transmembrane transport
DCS14_RS20100	COG1396	sequence-specific DNA binding
DCS14_RS20105	COG0747	negative chemotaxis
DCS14_RS20120	COG0776	regulation of translation
DCS14_RS20130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DCS14_RS20135	COG0740	serine-type endopeptidase activity
DCS14_RS20180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DCS14_RS20185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DCS14_RS20195	COG0584	glycerophosphoryl diester phosphodiesterase
DCS14_RS20200	COG0010	Belongs to the arginase family
DCS14_RS20215	COG1612	heme a metabolic process
DCS14_RS20245	COG0438	transferase activity, transferring glycosyl groups
DCS14_RS20250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DCS14_RS20290	COG0776	regulation of translation
DCS14_RS20295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCS14_RS20300	COG0416	fatty acid biosynthetic process
DCS14_RS20315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DCS14_RS20320	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DCS14_RS20335	COG1174	glycine betaine transport
DCS14_RS20340	COG1125	glycine betaine transport
DCS14_RS20345	COG1174	glycine betaine transport
DCS14_RS20350	COG1732	Glycine betaine
DCS14_RS20355	COG2814	Major facilitator Superfamily
DCS14_RS20360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCS14_RS20375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DCS14_RS20375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DCS14_RS20380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DCS14_RS20385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCS14_RS20390	COG2989	Protein conserved in bacteria
DCS14_RS20405	COG1024	Enoyl-CoA hydratase
DCS14_RS20410	COG0113	porphobilinogen synthase activity
DCS14_RS20420	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DCS14_RS20430	COG0628	permease
DCS14_RS20435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCS14_RS20445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DCS14_RS20460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DCS14_RS20490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DCS14_RS20520	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DCS14_RS20550	COG3842	ATPase activity
DCS14_RS20560	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS20580	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS20590	COG3845	ABC transporter
DCS14_RS20600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCS14_RS20630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCS14_RS20640	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS20645	COG4603	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS20650	COG3845	ABC transporter
DCS14_RS20655	COG1744	ABC transporter substrate-binding protein PnrA-like
DCS14_RS20665	COG2169	Transcriptional regulator
DCS14_RS20670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DCS14_RS20680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCS14_RS20695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS20705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCS14_RS20705	COG2111	Na H antiporter
DCS14_RS20710	COG1006	Multisubunit Na H antiporter MnhC subunit
DCS14_RS20715	COG0651	ATP synthesis coupled electron transport
DCS14_RS20720	COG1863	multisubunit Na H antiporter MnhE subunit
DCS14_RS20725	COG2212	antiporter activity
DCS14_RS20730	COG1320	monovalent cation:proton antiporter activity
DCS14_RS20740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DCS14_RS20745	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS20755	COG0367	asparagine synthase
DCS14_RS20760	COG2890	protein-(glutamine-N5) methyltransferase activity
DCS14_RS20810	COG1940	carbohydrate kinase activity
DCS14_RS20810	COG1846	Transcriptional regulator
DCS14_RS20845	COG2252	PERMEase
DCS14_RS20870	COG3842	ATPase activity
DCS14_RS20880	COG0395	ABC-type sugar transport system, permease component
DCS14_RS20895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCS14_RS20905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DCS14_RS20910	COG1132	(ABC) transporter
DCS14_RS20915	COG3459	Glycosyltransferase 36 associated
DCS14_RS20930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DCS14_RS20940	COG2986	histidine ammonia-lyase
DCS14_RS20945	COG1228	amidohydrolase
DCS14_RS20960	COG0251	oxidation-reduction process
DCS14_RS20965	COG1121	(ABC) transporter
DCS14_RS20970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCS14_RS20975	COG0803	Belongs to the bacterial solute-binding protein 9 family
DCS14_RS21010	COG1234	tRNA 3'-trailer cleavage
DCS14_RS21020	COG1063	alcohol dehydrogenase
DCS14_RS21035	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS21045	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS21055	COG1902	pentaerythritol trinitrate reductase activity
DCS14_RS21055	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS21060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DCS14_RS21075	COG5598	trimethylamine methyltransferase
DCS14_RS21080	COG0583	DNA-binding transcription factor activity
DCS14_RS21085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DCS14_RS21095	COG1663	tetraacyldisaccharide 4'-kinase activity
DCS14_RS21100	COG1519	Transferase
DCS14_RS21115	COG0483	inositol monophosphate 1-phosphatase activity
DCS14_RS21120	COG0312	modulator of DNA gyrase
DCS14_RS21135	COG0612	Peptidase, M16
DCS14_RS21140	COG0612	Peptidase, M16
DCS14_RS21150	COG0742	ribosomal rna small subunit methyltransferase
DCS14_RS21160	COG0590	tRNA wobble adenosine to inosine editing
DCS14_RS21170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCS14_RS21185	COG0196	riboflavin kinase activity
DCS14_RS21200	COG2814	Major facilitator Superfamily
DCS14_RS21215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCS14_RS21215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DCS14_RS21225	COG0459	protein refolding
DCS14_RS21235	COG3237	CsbD-like
DCS14_RS21240	COG0114	fumarate hydratase activity
DCS14_RS21245	COG2259	Doxx family
DCS14_RS21260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DCS14_RS21270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCS14_RS21280	COG1126	abc transporter atp-binding protein
DCS14_RS21285	COG0765	amino acid transport
DCS14_RS21290	COG4597	amino acid ABC transporter
DCS14_RS21295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS21305	COG0626	cystathionine gamma-synthase activity
DCS14_RS21345	COG2186	Transcriptional regulator
DCS14_RS21350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS14_RS21355	COG0129	dihydroxy-acid dehydratase activity
DCS14_RS21360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DCS14_RS21365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DCS14_RS21370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DCS14_RS21375	COG3734	2-keto-3-deoxy-galactonokinase
DCS14_RS21380	COG0800	Aldolase
DCS14_RS21400	COG0628	permease
DCS14_RS21410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DCS14_RS21415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DCS14_RS21430	COG0243	molybdopterin cofactor binding
DCS14_RS21435	COG0488	(ABC) transporter
DCS14_RS21455	COG0105	UTP biosynthetic process
DCS14_RS21460	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DCS14_RS21465	COG0314	molybdopterin synthase activity
DCS14_RS21480	COG0322	excinuclease ABC activity
DCS14_RS21485	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS21495	COG0625	glutathione transferase activity
DCS14_RS21510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DCS14_RS21535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCS14_RS21560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DCS14_RS21565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DCS14_RS21570	COG0194	GDP metabolic process
DCS14_RS21575	COG1561	YicC-like family, N-terminal region
DCS14_RS21580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DCS14_RS21585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCS14_RS21590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCS14_RS21600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DCS14_RS21605	COG1368	sulfuric ester hydrolase activity
DCS14_RS21610	COG0360	Binds together with S18 to 16S ribosomal RNA
DCS14_RS21620	COG0359	binds to the 23S rRNA
DCS14_RS21625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DCS14_RS21630	COG1742	UPF0060 membrane protein
DCS14_RS21640	COG0305	Participates in initiation and elongation during chromosome replication
DCS14_RS21660	COG2814	Major facilitator Superfamily
DCS14_RS21665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DCS14_RS21675	COG4221	oxidoreductase activity
DCS14_RS21680	COG0471	metal ion transport
DCS14_RS21680	COG3273	potassium ion transport
DCS14_RS21700	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS21700	COG0204	Acyl-transferase
DCS14_RS21710	COG0688	phosphatidylethanolamine metabolic process
DCS14_RS21725	COG5265	(ABC) transporter
DCS14_RS21735	COG1652	LysM domain
DCS14_RS21750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCS14_RS21780	COG2852	Protein conserved in bacteria
DCS14_RS21790	COG0215	cysteine-tRNA ligase activity
DCS14_RS21835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCS14_RS21845	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DCS14_RS21870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DCS14_RS21880	COG0640	Transcriptional regulator
DCS14_RS21900	COG1595	DNA-templated transcription, initiation
DCS14_RS21910	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
DCS14_RS21935	COG1381	Involved in DNA repair and RecF pathway recombination
DCS14_RS21955	COG2814	Major facilitator Superfamily
DCS14_RS21965	COG4221	oxidoreductase activity
DCS14_RS21995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DCS14_RS22000	COG1418	mRNA catabolic process
DCS14_RS22010	COG2195	Cleaves the N-terminal amino acid of tripeptides
DCS14_RS22040	COG0300	oxidoreductase activity
DCS14_RS22050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCS14_RS22055	COG0571	ribonuclease III activity
DCS14_RS22060	COG0681	Belongs to the peptidase S26 family
DCS14_RS22065	COG0736	holo-[acyl-carrier-protein] synthase activity
DCS14_RS22070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCS14_RS22080	COG1758	RNA polymerase activity
DCS14_RS22100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DCS14_RS22105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS14_RS22110	COG0741	lytic transglycosylase activity
DCS14_RS22115	COG2945	thiolester hydrolase activity
DCS14_RS22115	COG0596	Alpha beta hydrolase
DCS14_RS22150	COG4453	Protein conserved in bacteria
DCS14_RS22155	COG5489	Protein of unknown function (DUF736)
DCS14_RS22190	COG1192	Involved in chromosome partitioning
DCS14_RS22215	COG0741	lytic transglycosylase activity
DCS14_RS22235	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS14_RS22235	COG0596	Alpha beta hydrolase
DCS14_RS22240	COG0583	DNA-binding transcription factor activity
DCS14_RS22255	COG4962	Type ii secretion system protein e
DCS14_RS22270	COG3451	type IV secretory pathway VirB4
DCS14_RS22285	COG3846	protein secretion by the type IV secretion system
DCS14_RS22300	COG2948	multi-organism process
DCS14_RS22310	COG0583	DNA-binding transcription factor activity
DCS14_RS22325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCS14_RS22345	COG4991	sh3 domain protein
DCS14_RS22410	COG4974	Belongs to the 'phage' integrase family
DCS14_RS22425	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
DCS14_RS22430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCS14_RS22440	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS22460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCS14_RS22475	COG0450	alkyl hydroperoxide reductase
DCS14_RS22495	COG0625	glutathione transferase activity
DCS14_RS22505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DCS14_RS22530	COG1573	uracil-dna glycosylase
DCS14_RS22555	COG0308	aminopeptidase N
DCS14_RS22560	COG2205	protein histidine kinase activity
DCS14_RS22560	COG2202	Pas domain
DCS14_RS22570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DCS14_RS22575	COG2205	protein histidine kinase activity
DCS14_RS22580	COG0745	RESPONSE REGULATOR receiver
DCS14_RS22585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCS14_RS22590	COG3088	subunit of a heme lyase
DCS14_RS22595	COG1138	Cytochrome C-type biogenesis protein
DCS14_RS22600	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DCS14_RS22605	COG4235	cytochrome complex assembly
DCS14_RS22645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DCS14_RS22680	COG2205	protein histidine kinase activity
DCS14_RS22690	COG2166	iron-sulfur cluster assembly
DCS14_RS22700	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCS14_RS22710	COG4957	zinc ion binding
DCS14_RS22730	COG2010	Cytochrome c
DCS14_RS22740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DCS14_RS22745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS22755	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS22760	COG0433	COG0433 Predicted ATPase
DCS14_RS22770	COG3654	unkown
DCS14_RS22775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS22785	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS22790	COG0183	Belongs to the thiolase family
DCS14_RS22795	COG1309	transcriptional regulator
DCS14_RS22800	COG3119	arylsulfatase activity
DCS14_RS22810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DCS14_RS22815	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS22820	COG0662	Cupin 2, conserved barrel domain protein
DCS14_RS22820	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DCS14_RS22825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCS14_RS22955	COG0366	Alpha amylase catalytic
DCS14_RS22960	COG1523	belongs to the glycosyl hydrolase 13 family
DCS14_RS22965	COG0033	Phosphoglucomutase
DCS14_RS22970	COG0297	glycogen (starch) synthase activity
DCS14_RS22975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DCS14_RS22980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DCS14_RS22985	COG0058	SHG alpha-glucan phosphorylase activity
DCS14_RS23005	COG1940	carbohydrate kinase activity
DCS14_RS23025	COG1218	3'(2'),5'-bisphosphate nucleotidase
DCS14_RS23035	COG0175	sulfate reduction
DCS14_RS23065	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS23075	COG0574	Belongs to the PEP-utilizing enzyme family
DCS14_RS23075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCS14_RS23105	COG0189	ligase activity
DCS14_RS23135	COG0829	nickel cation binding
DCS14_RS23140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DCS14_RS23145	COG0804	urea catabolic process
DCS14_RS23150	COG0832	Belongs to the urease beta subunit family
DCS14_RS23150	COG0831	urea catabolic process
DCS14_RS23155	COG0830	nickel cation binding
DCS14_RS23200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS23215	COG0010	Belongs to the arginase family
DCS14_RS23250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCS14_RS23255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DCS14_RS23265	COG1196	nuclear chromosome segregation
DCS14_RS23270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DCS14_RS23280	COG1194	a g-specific adenine glycosylase
DCS14_RS23285	COG1011	Hydrolase
DCS14_RS23290	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DCS14_RS23295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCS14_RS23310	COG0612	Peptidase, M16
DCS14_RS23315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCS14_RS23325	COG1678	Uncharacterized ACR, COG1678
DCS14_RS23335	COG0678	peroxiredoxin activity
DCS14_RS23340	COG0328	RNA-DNA hybrid ribonuclease activity
DCS14_RS23345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DCS14_RS23350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DCS14_RS23355	COG3346	SURF1 family
DCS14_RS23375	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DCS14_RS23380	COG0109	protoheme IX farnesyltransferase activity
DCS14_RS23385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DCS14_RS23390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DCS14_RS23390	COG1565	acr, cog1565
DCS14_RS23410	COG0312	modulator of DNA gyrase
DCS14_RS23415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCS14_RS23425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DCS14_RS23430	COG1741	Belongs to the pirin family
DCS14_RS23440	COG1722	exodeoxyribonuclease VII activity
DCS14_RS23445	COG0123	including yeast histone deacetylase and acetoin utilization protein
DCS14_RS23450	COG1309	transcriptional regulator
DCS14_RS23470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCS14_RS23470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCS14_RS23475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DCS14_RS23485	COG0406	alpha-ribazole phosphatase activity
DCS14_RS23490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DCS14_RS23495	COG0484	heat shock protein binding
DCS14_RS23505	COG0259	pyridoxamine-phosphate oxidase activity
DCS14_RS23515	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS23530	COG0151	Belongs to the GarS family
DCS14_RS23535	COG4115	mRNA cleavage
DCS14_RS23560	COG0009	L-threonylcarbamoyladenylate synthase
DCS14_RS23575	COG0751	glycine-tRNA ligase activity
DCS14_RS23580	COG0752	glycyl-tRNA synthetase alpha subunit
DCS14_RS23590	COG0142	geranyltranstransferase activity
DCS14_RS23615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DCS14_RS23620	COG0521	Mo-molybdopterin cofactor biosynthetic process
DCS14_RS23640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DCS14_RS23645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCS14_RS23650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCS14_RS23655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCS14_RS23660	COG0356	it plays a direct role in the translocation of protons across the membrane
DCS14_RS23675	COG1160	GTP binding
DCS14_RS23690	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DCS14_RS23695	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DCS14_RS23705	COG0583	DNA-binding transcription factor activity
DCS14_RS23710	COG1393	Belongs to the ArsC family
DCS14_RS23715	COG1846	Transcriptional regulator
DCS14_RS23740	COG0640	Transcriptional regulator
DCS14_RS23745	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS23755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS14_RS23760	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS23765	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS23770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS23775	COG0601	transmembrane transport
DCS14_RS23790	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS23800	COG0494	nUDIX hydrolase
DCS14_RS23805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS23810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DCS14_RS23825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DCS14_RS23855	COG2176	DNA-directed DNA polymerase activity
DCS14_RS23860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DCS14_RS23895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCS14_RS23900	COG1111	helicase
DCS14_RS23900	COG1205	dead DEAH box helicase
DCS14_RS23925	COG1475	DNA binding
DCS14_RS23955	COG5489	Protein of unknown function (DUF736)
DCS14_RS23985	COG1192	Involved in chromosome partitioning
DCS14_RS24030	COG4962	Type ii secretion system protein e
DCS14_RS24035	COG3838	Conjugal transfer protein Trbc
DCS14_RS24045	COG3451	type IV secretory pathway VirB4
DCS14_RS24060	COG3846	protein secretion by the type IV secretion system
DCS14_RS24075	COG2948	multi-organism process
DCS14_RS24085	COG0583	DNA-binding transcription factor activity
DCS14_RS24130	COG1968	undecaprenyl-diphosphatase activity
DCS14_RS24135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DCS14_RS24165	COG0148	phosphopyruvate hydratase activity
DCS14_RS24170	COG0588	phosphoglycerate mutase activity
DCS14_RS24180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCS14_RS24190	COG0038	chloride channel
DCS14_RS24235	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DCS14_RS24245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DCS14_RS24250	COG0583	DNA-binding transcription factor activity
DCS14_RS24255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DCS14_RS24260	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DCS14_RS24265	COG0124	histidyl-tRNA synthetase
DCS14_RS24280	COG2818	Glycosylase
DCS14_RS24285	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS24295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCS14_RS24300	COG1376	ErfK ybiS ycfS ynhG family protein
DCS14_RS24305	COG0247	lactate metabolic process
DCS14_RS24325	COG0277	FAD linked oxidase domain protein
DCS14_RS24370	COG1309	transcriptional regulator
DCS14_RS24390	COG0583	DNA-binding transcription factor activity
DCS14_RS24395	COG1570	exodeoxyribonuclease VII activity
DCS14_RS24405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS14_RS24410	COG1178	ABC-type Fe3 transport system permease component
DCS14_RS24415	COG1840	ABC-type Fe3 transport system, periplasmic component
DCS14_RS24420	COG2205	protein histidine kinase activity
DCS14_RS24425	COG5490	Phasin protein
DCS14_RS24465	COG0443	Heat shock 70 kDa protein
DCS14_RS24485	COG1074	ATP-dependent DNA helicase activity
DCS14_RS24530	COG2224	Isocitrate lyase
DCS14_RS24550	COG0174	glutamine synthetase
DCS14_RS24560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS24580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DCS14_RS24585	COG0363	glucosamine-6-phosphate deaminase activity
DCS14_RS24590	COG0129	dihydroxy-acid dehydratase activity
DCS14_RS24610	COG0488	(ABC) transporter
DCS14_RS24625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCS14_RS24645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DCS14_RS24680	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DCS14_RS24685	COG4149	molybdate abc transporter
DCS14_RS24690	COG0725	ABC transporter, periplasmic molybdate-binding protein
DCS14_RS24695	COG0730	response to heat
DCS14_RS24700	COG0183	Belongs to the thiolase family
DCS14_RS24705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DCS14_RS24710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DCS14_RS24715	COG1414	Transcriptional regulator
DCS14_RS24725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCS14_RS24910	COG1783	phage Terminase large subunit
DCS14_RS24930	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCS14_RS25090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCS14_RS25100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DCS14_RS25105	COG5328	Belongs to the UPF0262 family
DCS14_RS25115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCS14_RS25120	COG0424	maF-like protein
DCS14_RS25125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DCS14_RS25145	COG4974	Belongs to the 'phage' integrase family
DCS14_RS25170	COG3706	GGDEF domain
DCS14_RS25310	COG4626	Terminase
DCS14_RS25310	COG1802	Transcriptional regulator
DCS14_RS25360	COG0328	RNA-DNA hybrid ribonuclease activity
DCS14_RS25425	COG0582	viral genome integration into host DNA
DCS14_RS25435	COG3300	MHYT domain
DCS14_RS25435	COG5001	Diguanylate cyclase
DCS14_RS25445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS25450	COG2186	Transcriptional regulator
DCS14_RS25485	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DCS14_RS25490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS25515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS14_RS25525	COG0251	oxidation-reduction process
DCS14_RS25535	COG0765	amino acid transport
DCS14_RS25540	COG0765	amino acid transport
DCS14_RS25560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DCS14_RS25565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS14_RS25570	COG1120	ATPase activity
DCS14_RS25575	COG3585	molybdate ion transport
DCS14_RS25580	COG1720	tRNA m6t6A37 methyltransferase activity
DCS14_RS25590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS25595	COG4215	(ABC) transporter
DCS14_RS25600	COG0765	amino acid transport
DCS14_RS25605	COG3457	Alanine racemase
DCS14_RS25610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS25620	COG0156	8-amino-7-oxononanoate synthase activity
DCS14_RS25625	COG0436	Aminotransferase
DCS14_RS25630	COG1970	mechanosensitive ion channel activity
DCS14_RS25635	COG2205	protein histidine kinase activity
DCS14_RS25635	COG0784	Response regulator, receiver
DCS14_RS25655	COG0167	dihydroorotate dehydrogenase activity
DCS14_RS25665	COG0123	including yeast histone deacetylase and acetoin utilization protein
DCS14_RS25685	COG0717	Belongs to the dCTP deaminase family
DCS14_RS25695	COG2967	ApaG domain
DCS14_RS25705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DCS14_RS25710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCS14_RS25720	COG0598	Magnesium transport protein CorA
DCS14_RS25725	COG0704	Plays a role in the regulation of phosphate uptake
DCS14_RS25730	COG5002	protein histidine kinase activity
DCS14_RS25735	COG2326	polyphosphate kinase activity
DCS14_RS25785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS25795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DCS14_RS25805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCS14_RS25815	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS25815	COG1024	Enoyl-CoA hydratase
DCS14_RS25820	COG0183	Belongs to the thiolase family
DCS14_RS25825	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS25835	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS25840	COG0789	Transcriptional regulator
DCS14_RS25850	COG0730	response to heat
DCS14_RS25865	COG1201	RNA secondary structure unwinding
DCS14_RS26160	COG3422	double-strand break repair
DCS14_RS26175	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS26180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS26190	COG0747	negative chemotaxis
DCS14_RS26195	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS26200	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS26205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS26210	COG0601	transmembrane transport
DCS14_RS26215	COG0747	negative chemotaxis
DCS14_RS26220	COG0318	PFAM AMP-dependent synthetase and ligase
DCS14_RS26230	COG0129	dihydroxy-acid dehydratase activity
DCS14_RS26275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS14_RS26280	COG0166	Belongs to the GPI family
DCS14_RS26290	COG0583	DNA-binding transcription factor activity
DCS14_RS26295	COG2814	Major facilitator Superfamily
DCS14_RS26300	COG0489	protein tyrosine kinase activity
DCS14_RS26325	COG0583	DNA-binding transcription factor activity
DCS14_RS26340	COG3383	formate dehydrogenase (NAD+) activity
DCS14_RS26345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DCS14_RS26355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS14_RS26385	COG1349	DNA-binding transcription factor activity
DCS14_RS26400	COG2340	Cysteine-rich secretory protein family
DCS14_RS26405	COG0697	spore germination
DCS14_RS26415	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS26420	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS26430	COG4603	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS26440	COG3845	ABC transporter
DCS14_RS26450	COG1132	(ABC) transporter
DCS14_RS26455	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS26460	COG0288	reversible hydration of carbon dioxide
DCS14_RS26480	COG1346	cytolysis
DCS14_RS26500	COG1733	regulation of RNA biosynthetic process
DCS14_RS26520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DCS14_RS26525	COG0594	ribonuclease P activity
DCS14_RS26530	COG0706	membrane insertase activity
DCS14_RS26540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DCS14_RS26545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS14_RS26550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DCS14_RS26565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DCS14_RS26580	COG3186	Phenylalanine-4-hydroxylase
DCS14_RS26590	COG3706	GGDEF domain
DCS14_RS26610	COG2171	N-acyltransferase activity
DCS14_RS26615	COG3152	Membrane
DCS14_RS26620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS14_RS26630	COG0101	tRNA pseudouridine synthase activity
DCS14_RS26640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCS14_RS26650	COG0242	peptide deformylase activity
DCS14_RS26690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS14_RS26705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DCS14_RS26710	COG3409	Peptidoglycan-binding domain 1 protein
DCS14_RS26710	COG3773	Cell wall hydrolase
DCS14_RS26720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DCS14_RS26725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DCS14_RS26740	COG2816	NAD+ diphosphatase activity
DCS14_RS26745	COG0456	acetyltransferase
DCS14_RS26745	COG1846	Transcriptional regulator
DCS14_RS26750	COG4106	trans-aconitate 2-methyltransferase activity
DCS14_RS26755	COG1605	Chorismate mutase
DCS14_RS26755	COG0077	Prephenate dehydratase
DCS14_RS26760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DCS14_RS26765	COG3474	cytochrome
DCS14_RS26770	COG4166	transmembrane transport
DCS14_RS26775	COG4166	transmembrane transport
DCS14_RS26780	COG4174	ABC transporter (Permease)
DCS14_RS26785	COG4239	(ABC) transporter, permease
DCS14_RS26795	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
DCS14_RS26800	COG4172	Belongs to the ABC transporter superfamily
DCS14_RS26820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCS14_RS26855	COG4964	Belongs to the GSP D family
DCS14_RS26890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DCS14_RS26895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCS14_RS26900	COG1024	Enoyl-CoA hydratase
DCS14_RS26905	COG0268	Binds directly to 16S ribosomal RNA
DCS14_RS26920	COG0765	amino acid transport
DCS14_RS26930	COG4208	sulfate ABC transporter
DCS14_RS26935	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS26940	COG3842	ATPase activity
DCS14_RS26955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DCS14_RS26965	COG0604	alcohol dehydrogenase
DCS14_RS26975	COG0277	FAD linked oxidase domain protein
DCS14_RS26985	COG3831	ATPase activity
DCS14_RS26990	COG1192	Involved in chromosome partitioning
DCS14_RS26995	COG1475	DNA binding
DCS14_RS27000	COG1414	Transcriptional regulator
DCS14_RS27045	COG0765	amino acid transport
DCS14_RS27050	COG0765	amino acid transport
DCS14_RS27070	COG1126	abc transporter atp-binding protein
DCS14_RS27075	COG0252	asparaginase activity
DCS14_RS27080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS27090	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS27095	COG1177	transmembrane transport
DCS14_RS27100	COG3842	ATPase activity
DCS14_RS27110	COG0196	riboflavin kinase activity
DCS14_RS27120	COG0625	glutathione transferase activity
DCS14_RS27125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DCS14_RS27130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS14_RS27135	COG2368	4-hydroxyphenylacetate
DCS14_RS27150	COG0583	DNA-binding transcription factor activity
DCS14_RS27155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS14_RS27160	COG1027	Aspartate ammonia-lyase
DCS14_RS27175	COG0242	peptide deformylase activity
DCS14_RS27190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCS14_RS27200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS27205	COG0431	NADPH-dependent FMN reductase
DCS14_RS27225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS14_RS27255	COG3593	DNA synthesis involved in DNA repair
DCS14_RS27260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DCS14_RS27270	COG0443	Heat shock 70 kDa protein
DCS14_RS27300	COG1177	transmembrane transport
DCS14_RS27310	COG2072	flavoprotein involved in K transport
DCS14_RS27325	COG3620	sequence-specific DNA binding
DCS14_RS27335	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS27340	COG2186	Transcriptional regulator
DCS14_RS27350	COG1129	ABC transporter
DCS14_RS27360	COG2017	converts alpha-aldose to the beta-anomer
DCS14_RS27365	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS27375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCS14_RS27420	COG1596	polysaccharide export
DCS14_RS27425	COG3206	protein involved in exopolysaccharide biosynthesis
DCS14_RS27425	COG0489	protein tyrosine kinase activity
DCS14_RS27440	COG0438	transferase activity, transferring glycosyl groups
DCS14_RS27450	COG0492	ferredoxin-NADP+ reductase activity
DCS14_RS27455	COG1522	sequence-specific DNA binding
DCS14_RS27465	COG3453	Protein conserved in bacteria
DCS14_RS27465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS14_RS27475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS27480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCS14_RS27490	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS27505	COG0302	gtp cyclohydrolase
DCS14_RS27520	COG4948	Mandelate Racemase Muconate Lactonizing
DCS14_RS27540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DCS14_RS27555	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DCS14_RS27570	COG1942	4-Oxalocrotonate Tautomerase
DCS14_RS27585	COG0154	amidase activity
DCS14_RS27590	COG0402	S-adenosylhomocysteine deaminase activity
DCS14_RS27605	COG0523	cobalamin synthesis protein
DCS14_RS27615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS27620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DCS14_RS27640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCS14_RS27650	COG1957	nucleoside hydrolase
DCS14_RS27655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS27675	COG0045	succinate-CoA ligase (ADP-forming) activity
DCS14_RS27680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DCS14_RS27685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCS14_RS27690	COG2379	hydroxypyruvate reductase
DCS14_RS27700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DCS14_RS27705	COG2218	PFAM glutamate synthase alpha subunit domain protein
DCS14_RS27710	COG0069	glutamate synthase activity
DCS14_RS27720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCS14_RS27730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS14_RS27730	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS14_RS27745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DCS14_RS27750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCS14_RS27805	COG0531	amino acid
DCS14_RS27830	COG1522	sequence-specific DNA binding
DCS14_RS27835	COG2826	transposase and inactivated derivatives, IS30 family
DCS14_RS27845	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DCS14_RS27855	COG0625	glutathione transferase activity
DCS14_RS27865	COG3842	ATPase activity
DCS14_RS27870	COG1840	ABC-type Fe3 transport system, periplasmic component
DCS14_RS27880	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS27890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DCS14_RS27895	COG1283	sodium-dependent phosphate transmembrane transporter activity
DCS14_RS27900	COG0583	DNA-binding transcription factor activity
DCS14_RS27910	COG3795	YCII-related domain
DCS14_RS27915	COG0488	(ABC) transporter
DCS14_RS27945	COG1349	DNA-binding transcription factor activity
DCS14_RS27960	COG4638	Rieske (2fe-2S)
DCS14_RS27975	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS27975	COG3347	Dehydrogenase
DCS14_RS27990	COG1129	ABC transporter
DCS14_RS27995	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS28000	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS28015	COG1070	Carbohydrate kinase
DCS14_RS28025	COG4952	isomerase
DCS14_RS28030	COG3254	rhamnose metabolic process
DCS14_RS28035	COG0235	Class ii aldolase
DCS14_RS28045	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS28050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS28055	COG0601	transmembrane transport
DCS14_RS28060	COG0747	negative chemotaxis
DCS14_RS28075	COG1473	amidohydrolase
DCS14_RS28080	COG1473	amidohydrolase
DCS14_RS28090	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DCS14_RS28095	COG2894	cell division
DCS14_RS28100	COG0850	regulation of cytokinetic process
DCS14_RS28105	COG2826	transposase and inactivated derivatives, IS30 family
DCS14_RS28130	COG0583	DNA-binding transcription factor activity
DCS14_RS28140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS14_RS28150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DCS14_RS28160	COG0154	amidase activity
DCS14_RS28170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCS14_RS28185	COG3845	ABC transporter
DCS14_RS28195	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS28225	COG1271	oxidase subunit
DCS14_RS28230	COG1294	oxidase, subunit
DCS14_RS28245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS14_RS28260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCS14_RS28290	COG3483	tryptophan 2,3-dioxygenase activity
DCS14_RS28310	COG0411	ABC transporter
DCS14_RS28325	COG4120	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS28330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCS14_RS28340	COG1802	Transcriptional regulator
DCS14_RS28345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCS14_RS28360	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS28365	COG1024	Enoyl-CoA hydratase
DCS14_RS28370	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS28385	COG1024	Enoyl-CoA hydratase
DCS14_RS28385	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS28395	COG0165	Argininosuccinate lyase
DCS14_RS28400	COG0395	ABC-type sugar transport system, permease component
DCS14_RS28405	COG1175	transmembrane transport
DCS14_RS28410	COG2182	Extracellular solute-binding protein
DCS14_RS28415	COG1940	carbohydrate kinase activity
DCS14_RS28430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS14_RS28435	COG4521	taurine ABC transporter
DCS14_RS28440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DCS14_RS28445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS14_RS28460	COG0028	Belongs to the TPP enzyme family
DCS14_RS28465	COG2855	membrane
DCS14_RS28480	COG2814	Major facilitator Superfamily
DCS14_RS28495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DCS14_RS28500	COG0583	DNA-binding transcription factor activity
DCS14_RS28505	COG0626	cystathionine gamma-synthase activity
DCS14_RS28525	COG1129	ABC transporter
DCS14_RS28550	COG4770	biotin carboxylase activity
DCS14_RS28555	COG0583	DNA-binding transcription factor activity
DCS14_RS28560	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DCS14_RS28570	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS28575	COG2084	Dehydrogenase
DCS14_RS28580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DCS14_RS28590	COG3842	ATPase activity
DCS14_RS28595	COG1177	transmembrane transport
DCS14_RS28600	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCS14_RS28620	COG0583	DNA-binding transcription factor activity
DCS14_RS28630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS28635	COG0601	transmembrane transport
DCS14_RS28640	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS28645	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS28650	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS28655	COG0747	negative chemotaxis
DCS14_RS28660	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS28670	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS28685	COG1024	Enoyl-CoA hydratase
DCS14_RS28690	COG1879	ABC-type sugar transport system periplasmic component
DCS14_RS28700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCS14_RS28715	COG4214	carbohydrate transport
DCS14_RS28720	COG1802	Transcriptional regulator
DCS14_RS28745	COG2301	Belongs to the HpcH HpaI aldolase family
DCS14_RS28755	COG2801	Transposase and inactivated derivatives
DCS14_RS28765	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS28770	COG0583	DNA-binding transcription factor activity
DCS14_RS28780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DCS14_RS28785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCS14_RS28790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DCS14_RS28805	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS28815	COG1129	ABC transporter
DCS14_RS28820	COG0473	3-isopropylmalate dehydrogenase activity
DCS14_RS28830	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS28835	COG0154	amidase activity
DCS14_RS28870	COG1104	cysteine desulfurase activity
DCS14_RS28960	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DCS14_RS28975	COG0626	cystathionine gamma-synthase activity
DCS14_RS28980	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS28990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS28995	COG0601	transmembrane transport
DCS14_RS29000	COG4166	transmembrane transport
DCS14_RS29010	COG0154	amidase activity
DCS14_RS29015	COG0583	DNA-binding transcription factor activity
DCS14_RS29030	COG4957	zinc ion binding
DCS14_RS29035	COG4608	Belongs to the ABC transporter superfamily
DCS14_RS29040	COG0444	Belongs to the ABC transporter superfamily
DCS14_RS29045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS14_RS29055	COG0747	negative chemotaxis
DCS14_RS29060	COG4221	oxidoreductase activity
DCS14_RS29100	COG0583	DNA-binding transcription factor activity
DCS14_RS29115	COG1126	abc transporter atp-binding protein
DCS14_RS29120	COG1609	Transcriptional regulator
DCS14_RS29135	COG1902	pentaerythritol trinitrate reductase activity
DCS14_RS29175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCS14_RS29205	COG0640	Transcriptional regulator
DCS14_RS29210	COG1475	DNA binding
DCS14_RS29215	COG1192	Involved in chromosome partitioning
DCS14_RS29235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS29240	COG0765	amino acid transport
DCS14_RS29245	COG0765	amino acid transport
DCS14_RS29250	COG1126	abc transporter atp-binding protein
DCS14_RS29255	COG3608	succinylglutamate desuccinylase aspartoacylase
DCS14_RS29265	COG3916	Acyl-homoserine-lactone synthase
DCS14_RS29270	COG2197	response regulator
DCS14_RS29285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DCS14_RS29315	COG0741	lytic transglycosylase activity
DCS14_RS29320	COG3838	Conjugal transfer protein Trbc
DCS14_RS29330	COG3451	type IV secretory pathway VirB4
DCS14_RS29335	COG0741	lytic transglycosylase activity
DCS14_RS29355	COG3736	Type IV secretory pathway, component VirB8
DCS14_RS29360	COG3504	Conjugal transfer protein
DCS14_RS29365	COG2948	multi-organism process
DCS14_RS29370	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DCS14_RS29420	COG3831	ATPase activity
DCS14_RS29490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DCS14_RS29495	COG1940	carbohydrate kinase activity
DCS14_RS29500	COG2188	Transcriptional regulator
DCS14_RS29510	COG1175	transmembrane transport
DCS14_RS29515	COG0395	ABC-type sugar transport system, permease component
DCS14_RS29520	COG3842	ATPase activity
DCS14_RS29535	COG0596	Alpha beta hydrolase
DCS14_RS29540	COG4221	oxidoreductase activity
DCS14_RS29555	COG1309	transcriptional regulator
DCS14_RS29570	COG0583	DNA-binding transcription factor activity
DCS14_RS29590	COG0596	Alpha beta hydrolase
DCS14_RS29595	COG3181	Tripartite tricarboxylate transporter family receptor
DCS14_RS29635	COG1129	ABC transporter
DCS14_RS29665	COG2188	Transcriptional regulator
DCS14_RS29680	COG1960	acyl-CoA dehydrogenase activity
DCS14_RS29690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCS14_RS29705	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS29725	COG3181	Tripartite tricarboxylate transporter family receptor
DCS14_RS29735	COG3436	PFAM IS66 Orf2 family protein
DCS14_RS29740	COG4372	Transposase
DCS14_RS29745	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS29755	COG0183	Belongs to the thiolase family
DCS14_RS29785	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS29890	COG0006	proline dipeptidase activity
DCS14_RS29895	COG3791	Glutathione-dependent formaldehyde-activating
DCS14_RS29900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DCS14_RS29905	COG3246	L-lysine catabolic process to acetate
DCS14_RS29925	COG1137	ATPase activity
DCS14_RS29930	COG1234	tRNA 3'-trailer cleavage
DCS14_RS29935	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS14_RS29990	COG3485	protocatechuate 3,4-dioxygenase
DCS14_RS30005	COG2084	Dehydrogenase
DCS14_RS30015	COG3842	ATPase activity
DCS14_RS30020	COG0395	ABC-type sugar transport system, permease component
DCS14_RS30060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DCS14_RS30090	COG5001	Diguanylate cyclase
DCS14_RS30090	COG3300	MHYT domain
DCS14_RS30105	COG3547	Transposase (IS116 IS110 IS902 family)
DCS14_RS30130	COG3384	dioxygenase
DCS14_RS30135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DCS14_RS30145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DCS14_RS30170	COG1414	Transcriptional regulator
DCS14_RS30175	COG0431	NADPH-dependent FMN reductase
DCS14_RS30235	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS30240	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCS14_RS30245	COG1129	ABC transporter
DCS14_RS30280	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS30300	COG1475	DNA binding
DCS14_RS30350	COG4227	nucleotidyltransferase activity
DCS14_RS30365	COG5489	Protein of unknown function (DUF736)
DCS14_RS30450	COG3701	Conjugal transfer protein
DCS14_RS30455	COG3846	protein secretion by the type IV secretion system
DCS14_RS30465	COG5314	conjugation
DCS14_RS30470	COG3451	type IV secretory pathway VirB4
DCS14_RS30480	COG3838	Conjugal transfer protein Trbc
DCS14_RS30485	COG4962	Type ii secretion system protein e
DCS14_RS30490	COG1192	Involved in chromosome partitioning
DCS14_RS30495	COG1475	DNA binding
DCS14_RS30500	COG1414	Transcriptional regulator
DCS14_RS30510	COG1959	2 iron, 2 sulfur cluster binding
DCS14_RS30525	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
DCS14_RS30595	COG2963	transposase activity
DCS14_RS30600	COG3436	PFAM IS66 Orf2 family protein
DCS14_RS30610	COG1126	abc transporter atp-binding protein
DCS14_RS30615	COG0765	amino acid transport
DCS14_RS30620	COG0765	amino acid transport
DCS14_RS30640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCS14_RS30650	COG0028	Belongs to the TPP enzyme family
DCS14_RS30655	COG1012	belongs to the aldehyde dehydrogenase family
DCS14_RS30665	COG1414	Transcriptional regulator
DCS14_RS30670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS14_RS30675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCS14_RS30680	COG1028	Short-chain dehydrogenase reductase Sdr
DCS14_RS30685	COG2084	Dehydrogenase
DCS14_RS30700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DCS14_RS30720	COG3621	Patatin-like phospholipase
DCS14_RS30735	COG1396	sequence-specific DNA binding
DCS14_RS30745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS14_RS30765	COG3547	Transposase (IS116 IS110 IS902 family)
DCS14_RS30820	COG2885	chlorophyll binding
DCS14_RS30845	COG2948	multi-organism process
DCS14_RS30865	COG3704	protein secretion by the type IV secretion system
DCS14_RS30895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCS14_RS30945	COG2197	response regulator
DCS14_RS30950	COG2205	protein histidine kinase activity
DCS14_RS30965	COG1027	Aspartate ammonia-lyase
DCS14_RS30970	COG0583	DNA-binding transcription factor activity
DCS14_RS30985	COG0765	amino acid transport
DCS14_RS30990	COG1126	abc transporter atp-binding protein
DCS14_RS30995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DCS14_RS31030	COG2003	Belongs to the UPF0758 family
DCS14_RS31130	COG1192	Involved in chromosome partitioning
DCS14_RS31155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DCS14_RS31220	COG2855	membrane
DCS14_RS31225	COG0583	DNA-binding transcription factor activity
DCS14_RS31230	COG1271	oxidase subunit
DCS14_RS31235	COG1294	oxidase, subunit
DCS14_RS31255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DCS14_RS31265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCS14_RS31275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD