locus-tag	class	description
N7E70_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_RS00040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_RS00050	COG0735	belongs to the Fur family
N7E70_RS00055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7E70_RS00065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7E70_RS00070	COG3300	MHYT domain
N7E70_RS00070	COG5001	Diguanylate cyclase
N7E70_RS00075	COG2813	Specifically methylates the guanine in position
N7E70_RS00085	COG1185	polyribonucleotide nucleotidyltransferase activity
N7E70_RS00090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N7E70_RS00095	COG0598	Magnesium transport protein CorA
N7E70_RS00100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7E70_RS00105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N7E70_RS00110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N7E70_RS00125	COG0779	Required for maturation of 30S ribosomal subunits
N7E70_RS00165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7E70_RS00170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N7E70_RS00175	COG1396	sequence-specific DNA binding
N7E70_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N7E70_RS00185	COG1253	flavin adenine dinucleotide binding
N7E70_RS00190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N7E70_RS00195	COG1702	phosphate starvation-inducible protein PhoH
N7E70_RS00200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_RS00220	COG1214	PFAM Peptidase M22, glycoprotease
N7E70_RS00225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_RS00260	COG0481	GTPase activity
N7E70_RS00280	COG3220	belongs to the UPF0276 family
N7E70_RS00325	COG0671	phosphoesterase, PA-phosphatase related
N7E70_RS00335	COG0659	secondary active sulfate transmembrane transporter activity
N7E70_RS00340	COG0443	Heat shock 70 kDa protein
N7E70_RS00355	COG2358	TRAP transporter, solute receptor (TAXI family
N7E70_RS00375	COG3795	YCII-related domain
N7E70_RS00390	COG0640	Transcriptional regulator
N7E70_RS00425	COG0842	Transport permease protein
N7E70_RS00430	COG1131	(ABC) transporter
N7E70_RS00445	COG2954	triphosphatase activity
N7E70_RS00465	COG1420	regulation of RNA biosynthetic process
N7E70_RS00470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N7E70_RS00480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N7E70_RS00485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_RS00505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N7E70_RS00510	COG0792	nuclease activity
N7E70_RS00520	COG1254	Belongs to the acylphosphatase family
N7E70_RS00525	COG2124	cytochrome p450
N7E70_RS00555	COG0745	RESPONSE REGULATOR receiver
N7E70_RS00560	COG2205	protein histidine kinase activity
N7E70_RS00565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
N7E70_RS00570	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N7E70_RS00575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N7E70_RS00600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N7E70_RS00605	COG2226	methyltransferase
N7E70_RS00610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N7E70_RS00615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N7E70_RS00635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N7E70_RS00650	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS00660	COG3845	ABC transporter
N7E70_RS00665	COG2900	Belongs to the SlyX family
N7E70_RS00675	COG1744	ABC transporter substrate-binding protein PnrA-like
N7E70_RS00680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_RS00730	COG1477	protein flavinylation
N7E70_RS00745	COG1136	(ABC) transporter
N7E70_RS00765	COG1278	Cold shock
N7E70_RS00800	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS00830	COG0251	oxidation-reduction process
N7E70_RS00845	COG0662	Cupin 2, conserved barrel domain protein
N7E70_RS00855	COG0848	biopolymer transport protein
N7E70_RS00905	COG1082	Xylose isomerase domain protein TIM barrel
N7E70_RS00910	COG4607	ABC-type enterochelin transport system periplasmic component
N7E70_RS00915	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS00920	COG4605	iron ion homeostasis
N7E70_RS00925	COG4604	ABC transporter, ATP-binding protein
N7E70_RS00930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7E70_RS00935	COG4638	Rieske (2fe-2S)
N7E70_RS00970	COG4771	TonB-dependent receptor
N7E70_RS00975	COG4178	(ABC) transporter
N7E70_RS00995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N7E70_RS01000	COG0459	protein refolding
N7E70_RS01040	COG0395	ABC-type sugar transport system, permease component
N7E70_RS01045	COG1175	transmembrane transport
N7E70_RS01060	COG1765	OsmC-like protein
N7E70_RS01065	COG2766	serine protein kinase
N7E70_RS01070	COG2718	Belongs to the UPF0229 family
N7E70_RS01075	COG2719	SpoVR family
N7E70_RS01080	COG3142	Participates in the control of copper homeostasis
N7E70_RS01085	COG1940	carbohydrate kinase activity
N7E70_RS01100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS01105	COG1446	asparaginase
N7E70_RS01115	COG0765	amino acid transport
N7E70_RS01120	COG0765	amino acid transport
N7E70_RS01155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS01195	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS01200	COG1957	nucleoside hydrolase
N7E70_RS01215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_RS01220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N7E70_RS01225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7E70_RS01230	COG1137	ATPase activity
N7E70_RS01235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N7E70_RS01245	COG0616	signal peptide processing
N7E70_RS01250	COG0776	regulation of translation
N7E70_RS01260	COG2423	ornithine cyclodeaminase activity
N7E70_RS01275	COG2378	regulation of single-species biofilm formation
N7E70_RS01280	COG0116	Belongs to the methyltransferase superfamily
N7E70_RS01280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N7E70_RS01285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7E70_RS01290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N7E70_RS01300	COG5002	protein histidine kinase activity
N7E70_RS01300	COG2205	protein histidine kinase activity
N7E70_RS01300	COG0784	Response regulator, receiver
N7E70_RS01325	COG1252	NADH dehydrogenase
N7E70_RS01330	COG2860	membrane
N7E70_RS01335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N7E70_RS01350	COG0175	sulfate reduction
N7E70_RS01355	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7E70_RS01365	COG1648	precorrin-2 dehydrogenase activity
N7E70_RS01365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7E70_RS01375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7E70_RS01375	COG4651	solute:proton antiporter activity
N7E70_RS01395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_RS01400	COG2131	deaminase
N7E70_RS01450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_RS01455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS01460	COG1942	4-Oxalocrotonate Tautomerase
N7E70_RS01480	COG1733	regulation of RNA biosynthetic process
N7E70_RS01490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_RS01490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_RS01505	COG0667	Aldo Keto reductase
N7E70_RS01510	COG0673	inositol 2-dehydrogenase activity
N7E70_RS01525	COG0395	ABC-type sugar transport system, permease component
N7E70_RS01530	COG1175	transmembrane transport
N7E70_RS01545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7E70_RS01555	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7E70_RS01560	COG1121	(ABC) transporter
N7E70_RS01565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_RS01575	COG3842	ATPase activity
N7E70_RS01580	COG0366	Alpha amylase catalytic
N7E70_RS01585	COG0395	ABC-type sugar transport system, permease component
N7E70_RS01590	COG1175	transmembrane transport
N7E70_RS01595	COG1653	transport
N7E70_RS01600	COG1609	Transcriptional regulator
N7E70_RS01605	COG1802	Transcriptional regulator
N7E70_RS01610	COG2272	Belongs to the type-B carboxylesterase lipase family
N7E70_RS01615	COG0543	2 iron, 2 sulfur cluster binding
N7E70_RS01615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7E70_RS01630	COG1595	DNA-templated transcription, initiation
N7E70_RS01640	COG1404	Belongs to the peptidase S8 family
N7E70_RS01660	COG3811	Belongs to the UPF0386 family
N7E70_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS01710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS01720	COG0154	amidase activity
N7E70_RS01725	COG0747	negative chemotaxis
N7E70_RS01730	COG0601	transmembrane transport
N7E70_RS01735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS01760	COG0625	glutathione transferase activity
N7E70_RS01850	COG1072	(Pantothenic acid kinase))
N7E70_RS01855	COG0625	glutathione transferase activity
N7E70_RS01870	COG0829	nickel cation binding
N7E70_RS01880	COG3813	Protein conserved in bacteria
N7E70_RS01890	COG0832	Belongs to the urease beta subunit family
N7E70_RS01915	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
N7E70_RS01920	COG0830	nickel cation binding
N7E70_RS01930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_RS01940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_RS01955	COG0534	Mate efflux family protein
N7E70_RS01970	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS01975	COG3842	ATPase activity
N7E70_RS01985	COG0765	amino acid transport
N7E70_RS01990	COG0765	amino acid transport
N7E70_RS02005	COG0583	DNA-binding transcription factor activity
N7E70_RS02010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N7E70_RS02035	COG1129	ABC transporter
N7E70_RS02050	COG1335	isochorismatase
N7E70_RS02080	COG1846	Transcriptional regulator
N7E70_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS02090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7E70_RS02115	COG0673	inositol 2-dehydrogenase activity
N7E70_RS02120	COG0395	ABC-type sugar transport system, permease component
N7E70_RS02135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N7E70_RS02140	COG2971	BadF BadG BcrA BcrD
N7E70_RS02145	COG2188	Transcriptional regulator
N7E70_RS02155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N7E70_RS02180	COG1879	ABC-type sugar transport system periplasmic component
N7E70_RS02190	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS02200	COG1609	Transcriptional regulator
N7E70_RS02210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS02220	COG4941	Belongs to the sigma-70 factor family
N7E70_RS02225	COG3795	YCII-related domain
N7E70_RS02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS02280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
N7E70_RS02285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N7E70_RS02290	COG4335	DNA alkylation repair
N7E70_RS02310	COG0121	glutamine amidotransferase
N7E70_RS02320	COG1522	sequence-specific DNA binding
N7E70_RS02325	COG0756	dUTP diphosphatase activity
N7E70_RS02330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_RS02335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7E70_RS02345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS02350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7E70_RS02360	COG0281	malic enzyme
N7E70_RS02360	COG0280	phosphate acetyltransferase
N7E70_RS02365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N7E70_RS02395	COG0596	Alpha beta hydrolase
N7E70_RS02410	COG2207	Transcriptional regulator
N7E70_RS02410	COG0662	Cupin 2, conserved barrel domain protein
N7E70_RS02445	COG5001	Diguanylate cyclase
N7E70_RS02445	COG5002	protein histidine kinase activity
N7E70_RS02455	COG0656	L-ascorbic acid biosynthetic process
N7E70_RS02475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N7E70_RS02480	COG0728	peptidoglycan biosynthetic process
N7E70_RS02495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7E70_RS02495	COG0463	Glycosyl transferase, family 2
N7E70_RS02500	COG0180	Tryptophanyl-tRNA synthetase
N7E70_RS02510	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N7E70_RS02515	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS02525	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
N7E70_RS02535	COG1643	Atp-dependent helicase
N7E70_RS02545	COG0673	inositol 2-dehydrogenase activity
N7E70_RS02550	COG1737	Transcriptional regulator
N7E70_RS02555	COG0129	dihydroxy-acid dehydratase activity
N7E70_RS02570	COG0626	cystathionine gamma-synthase activity
N7E70_RS02575	COG1846	Transcriptional regulator
N7E70_RS02580	COG0697	spore germination
N7E70_RS02600	COG1116	anion transmembrane transporter activity
N7E70_RS02620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS02650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_RS02655	COG1802	Transcriptional regulator
N7E70_RS02660	COG0579	oxidoreductase
N7E70_RS02670	COG1522	sequence-specific DNA binding
N7E70_RS02675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7E70_RS02680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS02685	COG2186	Transcriptional regulator
N7E70_RS02690	COG0626	cystathionine gamma-synthase activity
N7E70_RS02705	COG0395	ABC-type sugar transport system, permease component
N7E70_RS02710	COG3842	ATPase activity
N7E70_RS02715	COG0840	transmembrane signaling receptor activity
N7E70_RS02725	COG0745	RESPONSE REGULATOR receiver
N7E70_RS02730	COG0643	Histidine kinase
N7E70_RS02730	COG2198	Histidine kinase
N7E70_RS02735	COG0835	chemotaxis
N7E70_RS02740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N7E70_RS02745	COG2201	protein-glutamate methylesterase activity
N7E70_RS02750	COG0745	RESPONSE REGULATOR receiver
N7E70_RS02755	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N7E70_RS02815	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_RS02820	COG1063	alcohol dehydrogenase
N7E70_RS02830	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS02840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS02845	COG0601	transmembrane transport
N7E70_RS02860	COG2186	Transcriptional regulator
N7E70_RS02875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_RS02880	COG0346	lactoylglutathione lyase activity
N7E70_RS02885	COG0346	lactoylglutathione lyase activity
N7E70_RS02895	COG2124	cytochrome p450
N7E70_RS02920	COG1846	Transcriptional regulator
N7E70_RS02925	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
N7E70_RS02940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS02975	COG0436	Aminotransferase
N7E70_RS02990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_RS02995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_RS03000	COG1473	amidohydrolase
N7E70_RS03005	COG1957	nucleoside hydrolase
N7E70_RS03010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7E70_RS03020	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS03025	COG3842	ATPase activity
N7E70_RS03030	COG1177	transmembrane transport
N7E70_RS03035	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS03055	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_RS03065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS03070	COG0601	transmembrane transport
N7E70_RS03090	COG4172	Belongs to the ABC transporter superfamily
N7E70_RS03110	COG0747	negative chemotaxis
N7E70_RS03140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7E70_RS03145	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS03150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N7E70_RS03155	COG0539	negative regulation of cytoplasmic translation
N7E70_RS03175	COG1309	transcriptional regulator
N7E70_RS03185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS03190	COG4215	(ABC) transporter
N7E70_RS03200	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_RS03230	COG1968	undecaprenyl-diphosphatase activity
N7E70_RS03240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7E70_RS03250	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
N7E70_RS03255	COG1803	Methylglyoxal synthase
N7E70_RS03260	COG0837	glucose binding
N7E70_RS03265	COG1132	(ABC) transporter
N7E70_RS03270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7E70_RS03275	COG0588	phosphoglycerate mutase activity
N7E70_RS03315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7E70_RS03325	COG3386	PFAM SMP-30 Gluconolaconase
N7E70_RS03330	COG0800	Aldolase
N7E70_RS03335	COG3734	2-keto-3-deoxy-galactonokinase
N7E70_RS03340	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS03345	COG5001	Diguanylate cyclase
N7E70_RS03355	COG1309	transcriptional regulator
N7E70_RS03360	COG0189	ligase activity
N7E70_RS03375	COG5002	protein histidine kinase activity
N7E70_RS03375	COG3447	MASE1 domain protein
N7E70_RS03375	COG5001	Diguanylate cyclase
N7E70_RS03400	COG0284	orotidine-5'-phosphate decarboxylase activity
N7E70_RS03410	COG3963	phosphatidate phosphatase activity
N7E70_RS03415	COG0484	heat shock protein binding
N7E70_RS03425	COG0443	Heat shock 70 kDa protein
N7E70_RS03455	COG3038	cytochrome b561
N7E70_RS03465	COG0072	phenylalanine-tRNA ligase activity
N7E70_RS03465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_RS03475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N7E70_RS03480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N7E70_RS03485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N7E70_RS03495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N7E70_RS03505	COG3135	benzoate transporter
N7E70_RS03520	COG0583	DNA-binding transcription factor activity
N7E70_RS03525	COG0135	phosphoribosylanthranilate isomerase activity
N7E70_RS03530	COG0133	tryptophan synthase activity
N7E70_RS03535	COG0159	tryptophan synthase activity
N7E70_RS03540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N7E70_RS03555	COG1074	ATP-dependent DNA helicase activity
N7E70_RS03565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7E70_RS03570	COG3178	'Phosphotransferase
N7E70_RS03575	COG2205	protein histidine kinase activity
N7E70_RS03580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N7E70_RS03585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_RS03590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_RS03590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7E70_RS03600	COG2205	protein histidine kinase activity
N7E70_RS03605	COG0745	RESPONSE REGULATOR receiver
N7E70_RS03610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N7E70_RS03620	COG1652	LysM domain
N7E70_RS03630	COG1072	(Pantothenic acid kinase))
N7E70_RS03635	COG0140	phosphoribosyl-ATP diphosphatase activity
N7E70_RS03645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N7E70_RS03655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7E70_RS03665	COG0131	Imidazoleglycerol-phosphate dehydratase
N7E70_RS03670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N7E70_RS03690	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N7E70_RS03700	COG3800	Transcriptional regulator
N7E70_RS03700	COG1396	sequence-specific DNA binding
N7E70_RS03720	COG3030	protein affecting phage T7 exclusion by the F plasmid
N7E70_RS03725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
N7E70_RS03735	COG0237	dephospho-CoA kinase activity
N7E70_RS03740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N7E70_RS03745	COG0424	maF-like protein
N7E70_RS03750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N7E70_RS03755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N7E70_RS03760	COG1981	membrane
N7E70_RS03765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N7E70_RS03770	COG1331	Highly conserved protein containing a thioredoxin domain
N7E70_RS03775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N7E70_RS03780	COG0445	tRNA wobble uridine modification
N7E70_RS03785	COG0357	Ribosomal RNA small subunit methyltransferase G
N7E70_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_RS03865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N7E70_RS03865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N7E70_RS03875	COG4770	biotin carboxylase activity
N7E70_RS03880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7E70_RS03890	COG1396	sequence-specific DNA binding
N7E70_RS03890	COG3800	Transcriptional regulator
N7E70_RS03900	COG2183	response to ionizing radiation
N7E70_RS03905	COG0137	argininosuccinate synthase activity
N7E70_RS03935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7E70_RS03940	COG0287	Prephenate dehydrogenase
N7E70_RS03940	COG1605	Chorismate mutase
N7E70_RS03945	COG0228	four-way junction DNA binding
N7E70_RS03950	COG5001	Diguanylate cyclase
N7E70_RS03965	COG3781	membrane
N7E70_RS03975	COG0454	-acetyltransferase
N7E70_RS03980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N7E70_RS04000	COG4178	(ABC) transporter
N7E70_RS04005	COG3152	Membrane
N7E70_RS04010	COG0473	3-isopropylmalate dehydrogenase activity
N7E70_RS04020	COG0251	oxidation-reduction process
N7E70_RS04030	COG0066	3-isopropylmalate dehydratase activity
N7E70_RS04040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7E70_RS04045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS04050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS04055	COG1120	ATPase activity
N7E70_RS04060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_RS04070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_RS04075	COG0525	valine-tRNA ligase activity
N7E70_RS04080	COG0765	amino acid transport
N7E70_RS04085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS04100	COG2814	Major facilitator Superfamily
N7E70_RS04130	COG1595	DNA-templated transcription, initiation
N7E70_RS04165	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7E70_RS04180	COG2301	Belongs to the HpcH HpaI aldolase family
N7E70_RS04205	COG0587	DNA-directed DNA polymerase activity
N7E70_RS04210	COG2835	tetraacyldisaccharide 4'-kinase activity
N7E70_RS04215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N7E70_RS04220	COG3118	belongs to the thioredoxin family
N7E70_RS04240	COG0010	Belongs to the arginase family
N7E70_RS04245	COG0436	Aminotransferase
N7E70_RS04265	COG0463	Glycosyl transferase, family 2
N7E70_RS04270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS04280	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS04285	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_RS04295	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS04320	COG4154	Belongs to the RbsD FucU family
N7E70_RS04325	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS04330	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS04335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS04340	COG0601	transmembrane transport
N7E70_RS04345	COG0747	negative chemotaxis
N7E70_RS04355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7E70_RS04370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N7E70_RS04390	COG3339	Conserved Protein
N7E70_RS04395	COG2154	pterin-4-alpha-carbinolamine dehydratase
N7E70_RS04400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7E70_RS04415	COG1136	(ABC) transporter
N7E70_RS04420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N7E70_RS04425	COG0670	Belongs to the BI1 family
N7E70_RS04435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_RS04440	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS04460	COG1276	copper resistance
N7E70_RS04460	COG2372	response to copper ion
N7E70_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS04485	COG3300	MHYT domain
N7E70_RS04485	COG5001	Diguanylate cyclase
N7E70_RS04520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N7E70_RS04530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N7E70_RS04535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_RS04540	COG0552	protein localization to endoplasmic reticulum
N7E70_RS04545	COG2917	probably involved in intracellular septation
N7E70_RS04555	COG0431	NADPH-dependent FMN reductase
N7E70_RS04570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7E70_RS04580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7E70_RS04585	COG4133	protoheme IX ABC transporter activity
N7E70_RS04590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7E70_RS04605	COG0039	L-malate dehydrogenase activity
N7E70_RS04610	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_RS04615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7E70_RS04620	COG0567	Dehydrogenase, E1 component
N7E70_RS04625	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS04640	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS04680	COG4974	Belongs to the 'phage' integrase family
N7E70_RS04685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7E70_RS04705	COG0335	large ribosomal subunit rRNA binding
N7E70_RS04710	COG0456	acetyltransferase
N7E70_RS04730	COG0765	amino acid transport
N7E70_RS04765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N7E70_RS04780	COG2009	succinate dehydrogenase
N7E70_RS04810	COG3132	Protein of unknown function, DUF480
N7E70_RS04830	COG1764	response to oxidative stress
N7E70_RS04835	COG3795	YCII-related domain
N7E70_RS04840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_RS04845	COG1946	Acyl-CoA thioesterase
N7E70_RS04850	COG0347	Belongs to the P(II) protein family
N7E70_RS04855	COG0004	ammonium transporteR
N7E70_RS04875	COG1674	ftsk spoiiie
N7E70_RS04875	COG2261	transglycosylase associated protein
N7E70_RS04880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7E70_RS04895	COG0745	RESPONSE REGULATOR receiver
N7E70_RS04910	COG0583	DNA-binding transcription factor activity
N7E70_RS04915	COG2264	protein methyltransferase activity
N7E70_RS04930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N7E70_RS04935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N7E70_RS04940	COG0181	hydroxymethylbilane synthase activity
N7E70_RS04965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7E70_RS04990	COG3307	-O-antigen
N7E70_RS04995	COG1596	polysaccharide export
N7E70_RS05015	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS05025	COG2273	Hydrolase Family 16
N7E70_RS05060	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS05065	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS05070	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS05075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7E70_RS05080	COG3206	protein involved in exopolysaccharide biosynthesis
N7E70_RS05080	COG0489	protein tyrosine kinase activity
N7E70_RS05085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7E70_RS05095	COG3920	Histidine kinase
N7E70_RS05100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N7E70_RS05100	COG2755	lipolytic protein G-D-S-L family
N7E70_RS05110	COG3239	Fatty acid desaturase
N7E70_RS05130	COG3284	Transcriptional regulator
N7E70_RS05155	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS05165	COG3119	arylsulfatase activity
N7E70_RS05185	COG1940	carbohydrate kinase activity
N7E70_RS05190	COG0730	response to heat
N7E70_RS05195	COG1879	ABC-type sugar transport system periplasmic component
N7E70_RS05200	COG1802	Transcriptional regulator
N7E70_RS05205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_RS05220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS05230	COG0778	Nitroreductase
N7E70_RS05240	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_RS05255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS05270	COG0840	transmembrane signaling receptor activity
N7E70_RS05270	COG2972	Histidine kinase
N7E70_RS05280	COG0601	transmembrane transport
N7E70_RS05285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS05295	COG1228	amidohydrolase
N7E70_RS05300	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS05305	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS05310	COG1802	Transcriptional regulator
N7E70_RS05315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS05325	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS05330	COG0747	negative chemotaxis
N7E70_RS05335	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS05340	COG0583	DNA-binding transcription factor activity
N7E70_RS05345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS05350	COG0765	amino acid transport
N7E70_RS05360	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS05375	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS05380	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS05440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS05450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_RS05465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_RS05470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7E70_RS05505	COG1872	DUF167
N7E70_RS05515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N7E70_RS05535	COG1704	LemA family
N7E70_RS05565	COG2814	Major facilitator Superfamily
N7E70_RS05570	COG1846	Transcriptional regulator
N7E70_RS05575	COG0339	signal peptide processing
N7E70_RS05585	COG1217	gtp-binding protein TYPA
N7E70_RS05605	COG2270	Major facilitator Superfamily
N7E70_RS05610	COG0138	bifunctional purine biosynthesis protein purh
N7E70_RS05620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7E70_RS05620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_RS05625	COG0501	Belongs to the peptidase M48B family
N7E70_RS05650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7E70_RS05655	COG0789	Transcriptional regulator
N7E70_RS05665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_RS05670	COG5425	PFAM Usg family protein
N7E70_RS05685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N7E70_RS05690	COG0495	leucyl-tRNA aminoacylation
N7E70_RS05700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_RS05710	COG1522	sequence-specific DNA binding
N7E70_RS05715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7E70_RS05735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7E70_RS05745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N7E70_RS05750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N7E70_RS05755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N7E70_RS05760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_RS05765	COG0590	tRNA wobble adenosine to inosine editing
N7E70_RS05780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N7E70_RS05790	COG1091	dTDP-4-dehydrorhamnose reductase activity
N7E70_RS05800	COG3754	Rhamnan synthesis protein F
N7E70_RS05825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7E70_RS05825	COG3743	rRNA binding
N7E70_RS05830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N7E70_RS05845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N7E70_RS05850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7E70_RS05855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7E70_RS05860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N7E70_RS05875	COG0799	negative regulation of ribosome biogenesis
N7E70_RS05880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N7E70_RS05900	COG0793	Belongs to the peptidase S41A family
N7E70_RS05910	COG0494	nUDIX hydrolase
N7E70_RS05915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_RS05925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS05950	COG3655	Transcriptional regulator
N7E70_RS05975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS05980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS06020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N7E70_RS06030	COG2223	nitrite transmembrane transporter activity
N7E70_RS06035	COG0583	DNA-binding transcription factor activity
N7E70_RS06055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_RS06070	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS06080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N7E70_RS06085	COG0741	lytic transglycosylase activity
N7E70_RS06090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_RS06110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7E70_RS06115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N7E70_RS06130	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
N7E70_RS06135	COG0183	Belongs to the thiolase family
N7E70_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS06145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N7E70_RS06160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N7E70_RS06165	COG1329	Transcriptional regulator
N7E70_RS06180	COG1126	abc transporter atp-binding protein
N7E70_RS06185	COG0765	amino acid transport
N7E70_RS06190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS06205	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N7E70_RS06225	COG0488	(ABC) transporter
N7E70_RS06240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N7E70_RS06250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7E70_RS06255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N7E70_RS06285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7E70_RS06300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7E70_RS06305	COG0037	tRNA processing
N7E70_RS06315	COG2885	chlorophyll binding
N7E70_RS06330	COG0848	biopolymer transport protein
N7E70_RS06340	COG0824	Thioesterase
N7E70_RS06345	COG2226	methyltransferase
N7E70_RS06365	COG2255	four-way junction helicase activity
N7E70_RS06390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N7E70_RS06410	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS06430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N7E70_RS06435	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_RS06440	COG1272	protein, Hemolysin III
N7E70_RS06490	COG1132	(ABC) transporter
N7E70_RS06495	COG0254	rRNA binding
N7E70_RS06520	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7E70_RS06530	COG0217	transcriptional regulatory protein
N7E70_RS06560	COG1733	regulation of RNA biosynthetic process
N7E70_RS06580	COG0305	Participates in initiation and elongation during chromosome replication
N7E70_RS06585	COG0861	Integral membrane protein TerC family
N7E70_RS06590	COG1692	metallophosphoesterase
N7E70_RS06595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7E70_RS06630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_RS06650	COG0583	DNA-binding transcription factor activity
N7E70_RS06655	COG0431	NADPH-dependent FMN reductase
N7E70_RS06660	COG3750	Belongs to the UPF0335 family
N7E70_RS06680	COG0469	pyruvate kinase activity
N7E70_RS06685	COG2267	carboxylic ester hydrolase activity
N7E70_RS06690	COG0457	Tetratricopeptide repeat
N7E70_RS06695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N7E70_RS06700	COG3755	Protein conserved in bacteria
N7E70_RS06705	COG1733	regulation of RNA biosynthetic process
N7E70_RS06715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7E70_RS06735	COG0640	Transcriptional regulator
N7E70_RS06750	COG0604	alcohol dehydrogenase
N7E70_RS06750	COG3321	synthase
N7E70_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS06755	COG2226	methyltransferase
N7E70_RS06765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS06775	COG0145	ligase activity
N7E70_RS06780	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
N7E70_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS06810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_RS06810	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_RS06810	COG1042	CoA-binding domain protein
N7E70_RS06820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS06825	COG0697	spore germination
N7E70_RS06840	COG0183	Belongs to the thiolase family
N7E70_RS06860	COG4191	Histidine kinase
N7E70_RS06890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS06905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS07060	COG3588	fructose-bisphosphate aldolase
N7E70_RS07070	COG0126	phosphoglycerate kinase activity
N7E70_RS07110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7E70_RS07120	COG0564	pseudouridine synthase activity
N7E70_RS07130	COG0346	lactoylglutathione lyase activity
N7E70_RS07335	COG0573	inorganic phosphate transmembrane transporter activity
N7E70_RS07345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7E70_RS07350	COG0704	Plays a role in the regulation of phosphate uptake
N7E70_RS07355	COG0745	RESPONSE REGULATOR receiver
N7E70_RS07365	COG4213	ABC transporter substrate-binding protein
N7E70_RS07370	COG4214	carbohydrate transport
N7E70_RS07395	COG2202	Pas domain
N7E70_RS07395	COG3920	Histidine kinase
N7E70_RS07405	COG0784	Response regulator, receiver
N7E70_RS07420	COG0784	Response regulator, receiver
N7E70_RS07425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_RS07430	COG0628	permease
N7E70_RS07470	COG0346	lactoylglutathione lyase activity
N7E70_RS07475	COG0400	carboxylic ester hydrolase activity
N7E70_RS07495	COG2203	Gaf domain
N7E70_RS07495	COG2200	EAL domain
N7E70_RS07495	COG2199	diguanylate cyclase activity
N7E70_RS07500	COG0745	RESPONSE REGULATOR receiver
N7E70_RS07505	COG0745	RESPONSE REGULATOR receiver
N7E70_RS07520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7E70_RS07525	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N7E70_RS07530	COG3833	ABC-type maltose transport systems, permease component
N7E70_RS07535	COG3842	ATPase activity
N7E70_RS07555	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_RS07560	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_RS07585	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_RS07595	COG3842	ATPase activity
N7E70_RS07600	COG1238	metal cluster binding
N7E70_RS07610	COG2132	Multicopper oxidase
N7E70_RS07645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7E70_RS07650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7E70_RS07660	COG1845	cytochrome c oxidase, subunit III
N7E70_RS07675	COG0406	alpha-ribazole phosphatase activity
N7E70_RS07680	COG3842	ATPase activity
N7E70_RS07685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N7E70_RS07705	COG1737	Transcriptional regulator
N7E70_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS07730	COG0395	ABC-type sugar transport system, permease component
N7E70_RS07740	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS07745	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS07750	COG3845	ABC transporter
N7E70_RS07760	COG2186	Transcriptional regulator
N7E70_RS07780	COG0625	glutathione transferase activity
N7E70_RS07785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N7E70_RS07790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N7E70_RS07795	COG0351	phosphomethylpyrimidine kinase
N7E70_RS07795	COG0352	thiamine-phosphate diphosphorylase activity
N7E70_RS07795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7E70_RS07805	COG2022	thiamine diphosphate biosynthetic process
N7E70_RS07820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N7E70_RS07845	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_RS07860	COG1473	amidohydrolase
N7E70_RS07865	COG1686	Belongs to the peptidase S11 family
N7E70_RS07870	COG0523	cobalamin synthesis protein
N7E70_RS07875	COG0425	Belongs to the sulfur carrier protein TusA family
N7E70_RS07885	COG0825	malonyl-CoA metabolic process
N7E70_RS07900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N7E70_RS07905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N7E70_RS07910	COG4536	flavin adenine dinucleotide binding
N7E70_RS07970	COG1522	sequence-specific DNA binding
N7E70_RS07995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N7E70_RS08000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N7E70_RS08025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_RS08030	COG2226	methyltransferase
N7E70_RS08045	COG1597	lipid kinase activity
N7E70_RS08055	COG2814	Major facilitator Superfamily
N7E70_RS08060	COG0583	DNA-binding transcription factor activity
N7E70_RS08065	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N7E70_RS08070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7E70_RS08075	COG0287	Prephenate dehydrogenase
N7E70_RS08090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_RS08090	COG2169	Transcriptional regulator
N7E70_RS08115	COG2884	Cell division ATP-binding protein ftsE
N7E70_RS08125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N7E70_RS08140	COG0583	DNA-binding transcription factor activity
N7E70_RS08150	COG0019	diaminopimelate decarboxylase activity
N7E70_RS08160	COG0165	Argininosuccinate lyase
N7E70_RS08165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7E70_RS08170	COG1653	transport
N7E70_RS08175	COG1175	transmembrane transport
N7E70_RS08180	COG0395	ABC-type sugar transport system, permease component
N7E70_RS08185	COG3842	ATPase activity
N7E70_RS08195	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_RS08200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N7E70_RS08205	COG2086	electron transfer activity
N7E70_RS08225	COG0300	oxidoreductase activity
N7E70_RS08235	COG0697	spore germination
N7E70_RS08245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_RS08265	COG1238	metal cluster binding
N7E70_RS08295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_RS08315	COG2239	Acts as a magnesium transporter
N7E70_RS08320	COG0653	protein targeting
N7E70_RS08325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7E70_RS08345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7E70_RS08350	COG0456	acetyltransferase
N7E70_RS08355	COG0494	nUDIX hydrolase
N7E70_RS08370	COG2226	methyltransferase
N7E70_RS08385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7E70_RS08410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_RS08415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS08420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N7E70_RS08425	COG0527	aspartate kinase activity
N7E70_RS08435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N7E70_RS08440	COG2890	protein-(glutamine-N5) methyltransferase activity
N7E70_RS08450	COG0542	response to heat
N7E70_RS08460	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS08485	COG0625	glutathione transferase activity
N7E70_RS08490	COG0477	Major facilitator Superfamily
N7E70_RS08495	COG0739	heme binding
N7E70_RS08495	COG0741	lytic transglycosylase activity
N7E70_RS08495	COG1196	nuclear chromosome segregation
N7E70_RS08665	COG2433	Pfam Transposase IS66
N7E70_RS08670	COG3436	PFAM IS66 Orf2 family protein
N7E70_RS08680	COG2433	Pfam Transposase IS66
N7E70_RS08685	COG3436	PFAM IS66 Orf2 family protein
N7E70_RS08715	COG0010	Belongs to the arginase family
N7E70_RS08755	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS08765	COG3842	ATPase activity
N7E70_RS08785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS08785	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS08805	COG0583	DNA-binding transcription factor activity
N7E70_RS08825	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS08830	COG3842	ATPase activity
N7E70_RS08840	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS08850	COG0583	DNA-binding transcription factor activity
N7E70_RS08885	COG0435	Glutathione S-transferase
N7E70_RS08925	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_RS08930	COG3448	diguanylate cyclase activity
N7E70_RS08930	COG4175	Glycine betaine
N7E70_RS08940	COG0745	RESPONSE REGULATOR receiver
N7E70_RS08945	COG2205	protein histidine kinase activity
N7E70_RS08955	COG0745	RESPONSE REGULATOR receiver
N7E70_RS08965	COG1879	ABC-type sugar transport system periplasmic component
N7E70_RS08970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS08975	COG3842	ATPase activity
N7E70_RS08995	COG1070	Carbohydrate kinase
N7E70_RS09005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N7E70_RS09010	COG0667	Aldo Keto reductase
N7E70_RS09020	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS09025	COG1129	ABC transporter
N7E70_RS09035	COG2358	TRAP transporter, solute receptor (TAXI family
N7E70_RS09045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS09055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_RS09095	COG0463	Glycosyl transferase, family 2
N7E70_RS09100	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS09120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS09125	COG1120	ATPase activity
N7E70_RS09130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_RS09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_RS09150	COG0205	6-phosphofructokinase activity
N7E70_RS09155	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS09155	COG1388	LysM domain
N7E70_RS09160	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS09170	COG1070	Carbohydrate kinase
N7E70_RS09180	COG2115	Belongs to the xylose isomerase family
N7E70_RS09195	COG1011	Hydrolase
N7E70_RS09200	COG4977	sequence-specific DNA binding
N7E70_RS09205	COG3246	L-lysine catabolic process to acetate
N7E70_RS09210	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_RS09230	COG0657	acetylesterase activity
N7E70_RS09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS09265	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N7E70_RS09270	COG3257	ureidoglycine aminohydrolase activity
N7E70_RS09280	COG2351	hydroxyisourate hydrolase activity
N7E70_RS09290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7E70_RS09300	COG0783	Belongs to the Dps family
N7E70_RS09315	COG0583	DNA-binding transcription factor activity
N7E70_RS09325	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS09330	COG4702	Belongs to the UPF0303 family
N7E70_RS09350	COG0174	glutamine synthetase
N7E70_RS09380	COG0523	cobalamin synthesis protein
N7E70_RS09390	COG1846	Transcriptional regulator
N7E70_RS09405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_RS09420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
N7E70_RS09425	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_RS09430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_RS09445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_RS09445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N7E70_RS09475	COG5001	Diguanylate cyclase
N7E70_RS09515	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS09525	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7E70_RS09535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N7E70_RS09555	COG2223	nitrite transmembrane transporter activity
N7E70_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS09580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS09600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS09600	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS09660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_RS09700	COG0583	DNA-binding transcription factor activity
N7E70_RS09705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N7E70_RS09710	COG3842	ATPase activity
N7E70_RS09715	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS09720	COG1177	transmembrane transport
N7E70_RS09725	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS09740	COG1609	Transcriptional regulator
N7E70_RS09755	COG1024	Enoyl-CoA hydratase
N7E70_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS09765	COG1653	transport
N7E70_RS09775	COG0395	ABC-type sugar transport system, permease component
N7E70_RS09780	COG3842	ATPase activity
N7E70_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS09800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7E70_RS09805	COG3774	pathogenesis
N7E70_RS09810	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS09815	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS09820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS09830	COG4533	DNA binding
N7E70_RS09835	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS09865	COG2072	flavoprotein involved in K transport
N7E70_RS09895	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_RS09905	COG0069	glutamate synthase activity
N7E70_RS09905	COG0067	glutamate synthase
N7E70_RS09905	COG0070	glutamate synthase
N7E70_RS09920	COG2951	lytic endotransglycosylase activity
N7E70_RS09925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7E70_RS09930	COG0778	Nitroreductase
N7E70_RS09955	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7E70_RS09960	COG0330	HflC and HflK could
N7E70_RS09965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N7E70_RS09965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS09970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N7E70_RS09975	COG0737	Belongs to the 5'-nucleotidase family
N7E70_RS09985	COG3775	system Galactitol-specific IIC component
N7E70_RS10000	COG5310	Homospermidine synthase
N7E70_RS10035	COG2204	response regulator
N7E70_RS10040	COG3108	Peptidase M15
N7E70_RS10045	COG0800	Aldolase
N7E70_RS10055	COG1054	Belongs to the UPF0176 family
N7E70_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS10120	COG0583	DNA-binding transcription factor activity
N7E70_RS10125	COG0154	amidase activity
N7E70_RS10175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7E70_RS10180	COG2814	Major facilitator Superfamily
N7E70_RS10190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N7E70_RS10195	COG5443	negative regulation of bacterial-type flagellum assembly
N7E70_RS10200	COG5442	Flagellar protein FlaF
N7E70_RS10215	COG1749	Flagellar hook protein flgE
N7E70_RS10255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_RS10260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_RS10265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_RS10275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_RS10280	COG1338	Plays a role in the flagellum-specific transport system
N7E70_RS10290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
N7E70_RS10300	COG1706	bacterial-type flagellum-dependent cell motility
N7E70_RS10305	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
N7E70_RS10310	COG4786	Flagellar basal body rod
N7E70_RS10315	COG1677	Flagellar hook-basal body complex protein FliE
N7E70_RS10320	COG1558	bacterial-type flagellum-dependent cell motility
N7E70_RS10325	COG1815	bacterial-type flagellum-dependent cell motility
N7E70_RS10335	COG1157	protein secretion by the type III secretion system
N7E70_RS10340	COG4786	Flagellar basal body rod
N7E70_RS10350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7E70_RS10360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7E70_RS10365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7E70_RS10370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7E70_RS10385	COG2771	luxR family
N7E70_RS10400	COG1309	transcriptional regulator
N7E70_RS10405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N7E70_RS10410	COG3842	ATPase activity
N7E70_RS10420	COG1177	transmembrane transport
N7E70_RS10450	COG4213	ABC transporter substrate-binding protein
N7E70_RS10455	COG1129	ABC transporter
N7E70_RS10460	COG4214	carbohydrate transport
N7E70_RS10510	COG1129	ABC transporter
N7E70_RS10515	COG4211	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS10520	COG0673	inositol 2-dehydrogenase activity
N7E70_RS10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS10530	COG3962	Belongs to the TPP enzyme family
N7E70_RS10535	COG1082	Xylose isomerase domain protein TIM barrel
N7E70_RS10545	COG3718	enzyme involved in inositol metabolism
N7E70_RS10550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_RS10580	COG2197	response regulator
N7E70_RS10600	COG0747	negative chemotaxis
N7E70_RS10625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS10630	COG0747	negative chemotaxis
N7E70_RS10645	COG3454	Phosphonate metabolism
N7E70_RS10650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
N7E70_RS10655	COG3639	organic phosphonate transmembrane transporter activity
N7E70_RS10670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
N7E70_RS10675	COG1733	regulation of RNA biosynthetic process
N7E70_RS10690	COG0786	glutamate:sodium symporter activity
N7E70_RS10700	COG4778	phosphonate C-P lyase system protein PhnL
N7E70_RS10705	COG4107	phosphonate C-P lyase system protein PhnK
N7E70_RS10710	COG3627	carbon phosphorus lyase activity
N7E70_RS10715	COG3626	phosphonate metabolism
N7E70_RS10720	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
N7E70_RS10725	COG3624	Phosphonate C-P lyase system protein PhnG
N7E70_RS10730	COG2188	Transcriptional regulator
N7E70_RS10745	COG1177	transmembrane transport
N7E70_RS10755	COG2072	flavoprotein involved in K transport
N7E70_RS10770	COG3620	sequence-specific DNA binding
N7E70_RS10800	COG0583	DNA-binding transcription factor activity
N7E70_RS10810	COG3842	ATPase activity
N7E70_RS10820	COG1175	transmembrane transport
N7E70_RS10845	COG1192	Involved in chromosome partitioning
N7E70_RS10855	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N7E70_RS10860	COG0322	excinuclease ABC activity
N7E70_RS10865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N7E70_RS10940	COG0482	sulfurtransferase activity
N7E70_RS10955	COG0604	alcohol dehydrogenase
N7E70_RS10960	COG1733	regulation of RNA biosynthetic process
N7E70_RS10975	COG2201	protein-glutamate methylesterase activity
N7E70_RS11020	COG0435	Glutathione S-transferase
N7E70_RS11025	COG0494	nUDIX hydrolase
N7E70_RS11040	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS11040	COG0596	Alpha beta hydrolase
N7E70_RS11050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7E70_RS11060	COG3180	Ammonia monooxygenase
N7E70_RS11090	COG0512	Glutamine amidotransferase of anthranilate synthase
N7E70_RS11090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7E70_RS11095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS11105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N7E70_RS11110	COG2814	Major facilitator Superfamily
N7E70_RS11115	COG0583	DNA-binding transcription factor activity
N7E70_RS11120	COG4993	Dehydrogenase
N7E70_RS11130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7E70_RS11150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7E70_RS11185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N7E70_RS11215	COG1435	thymidine kinase activity
N7E70_RS11225	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_RS11230	COG4175	Glycine betaine
N7E70_RS11230	COG3448	diguanylate cyclase activity
N7E70_RS11250	COG5507	3-demethylubiquinone-9 3-methyltransferase
N7E70_RS11255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N7E70_RS11280	COG1278	Cold shock
N7E70_RS11305	COG0714	Associated with various cellular activities
N7E70_RS11315	COG0494	nUDIX hydrolase
N7E70_RS11320	COG0617	tRNA 3'-terminal CCA addition
N7E70_RS11340	COG0408	coproporphyrinogen oxidase activity
N7E70_RS11370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7E70_RS11380	COG1132	(ABC) transporter
N7E70_RS11385	COG1132	(ABC) transporter
N7E70_RS11390	COG1132	(ABC) transporter
N7E70_RS11410	COG2857	Cytochrome c1
N7E70_RS11410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7E70_RS11415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7E70_RS11445	COG0012	GTP binding
N7E70_RS11450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7E70_RS11465	COG0193	aminoacyl-tRNA hydrolase activity
N7E70_RS11470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N7E70_RS11490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7E70_RS11505	COG1496	oxidoreductase activity
N7E70_RS11515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N7E70_RS11530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_RS11540	COG1464	Belongs to the NlpA lipoprotein family
N7E70_RS11545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7E70_RS11550	COG2011	ABC-type metal ion transport system permease component
N7E70_RS11555	COG2205	protein histidine kinase activity
N7E70_RS11565	COG0745	RESPONSE REGULATOR receiver
N7E70_RS11570	COG1846	Transcriptional regulator
N7E70_RS11575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_RS11595	COG1278	Cold shock
N7E70_RS11605	COG1278	Cold shock
N7E70_RS11625	COG0583	DNA-binding transcription factor activity
N7E70_RS11635	COG1819	glycosyl
N7E70_RS11640	COG1309	transcriptional regulator
N7E70_RS11645	COG1794	racemase activity, acting on amino acids and derivatives
N7E70_RS11655	COG3791	Glutathione-dependent formaldehyde-activating
N7E70_RS11665	COG0726	polysaccharide deacetylase
N7E70_RS11685	COG1396	sequence-specific DNA binding
N7E70_RS11715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS11725	COG1522	sequence-specific DNA binding
N7E70_RS11740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS11755	COG0583	DNA-binding transcription factor activity
N7E70_RS11770	COG0556	nucleotide-excision repair
N7E70_RS11780	COG0438	transferase activity, transferring glycosyl groups
N7E70_RS11810	COG1597	lipid kinase activity
N7E70_RS11830	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS11860	COG1253	flavin adenine dinucleotide binding
N7E70_RS11905	COG0583	DNA-binding transcription factor activity
N7E70_RS11915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_RS11930	COG2133	pyrroloquinoline quinone binding
N7E70_RS11935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_RS11950	COG3306	glycosyltransferase involved in LPS biosynthesis
N7E70_RS11955	COG3306	glycosyltransferase involved in LPS biosynthesis
N7E70_RS11965	COG1522	sequence-specific DNA binding
N7E70_RS11970	COG0492	ferredoxin-NADP+ reductase activity
N7E70_RS11975	COG0583	DNA-binding transcription factor activity
N7E70_RS11980	COG0640	Transcriptional regulator
N7E70_RS12005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7E70_RS12010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7E70_RS12025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_RS12035	COG0477	Major facilitator Superfamily
N7E70_RS12065	COG0436	Aminotransferase
N7E70_RS12085	COG1278	Cold shock
N7E70_RS12095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_RS12120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7E70_RS12125	COG2130	NADP-dependent
N7E70_RS12135	COG1864	DNA RNA non-specific endonuclease
N7E70_RS12135	COG3591	Belongs to the peptidase S1B family
N7E70_RS12150	COG2814	Major facilitator Superfamily
N7E70_RS12155	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS12165	COG2321	neutral zinc metallopeptidase
N7E70_RS12170	COG4989	oxidoreductase activity
N7E70_RS12190	COG1116	anion transmembrane transporter activity
N7E70_RS12210	COG0505	Belongs to the CarA family
N7E70_RS12225	COG1473	amidohydrolase
N7E70_RS12235	COG0358	DNA primase activity
N7E70_RS12240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7E70_RS12255	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N7E70_RS12270	COG0372	Belongs to the citrate synthase family
N7E70_RS12275	COG0372	Belongs to the citrate synthase family
N7E70_RS12320	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS12365	COG0488	(ABC) transporter
N7E70_RS12380	COG1522	sequence-specific DNA binding
N7E70_RS12390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7E70_RS12395	COG0583	DNA-binding transcription factor activity
N7E70_RS12400	COG1309	transcriptional regulator
N7E70_RS12425	COG2862	Uncharacterized protein family, UPF0114
N7E70_RS12435	COG2983	Belongs to the UPF0260 family
N7E70_RS12445	COG2968	Membrane
N7E70_RS12480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_RS12495	COG2814	Major facilitator Superfamily
N7E70_RS12505	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS12510	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS12515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS12520	COG0601	transmembrane transport
N7E70_RS12525	COG0747	negative chemotaxis
N7E70_RS12540	COG1473	amidohydrolase
N7E70_RS12545	COG1473	amidohydrolase
N7E70_RS12550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS12555	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS12565	COG5383	Protein conserved in bacteria
N7E70_RS12575	COG0837	glucose binding
N7E70_RS12575	COG1737	Transcriptional regulator
N7E70_RS12580	COG0747	negative chemotaxis
N7E70_RS12585	COG0601	transmembrane transport
N7E70_RS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS12595	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS12620	COG3706	GGDEF domain
N7E70_RS12635	COG0463	Glycosyl transferase, family 2
N7E70_RS12690	COG0367	asparagine synthase
N7E70_RS12700	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS12705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7E70_RS12740	COG1902	pentaerythritol trinitrate reductase activity
N7E70_RS12760	COG0673	inositol 2-dehydrogenase activity
N7E70_RS12770	COG0589	response to stress
N7E70_RS12775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS12780	COG4597	amino acid ABC transporter
N7E70_RS12785	COG0765	amino acid transport
N7E70_RS12790	COG3685	Protein conserved in bacteria
N7E70_RS12800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7E70_RS12805	COG4208	sulfate ABC transporter
N7E70_RS12810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N7E70_RS12815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N7E70_RS12825	COG4953	penicillin-binding protein 1C
N7E70_RS12835	COG0729	surface antigen
N7E70_RS12845	COG4166	transmembrane transport
N7E70_RS12850	COG0601	transmembrane transport
N7E70_RS12855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS12870	COG0493	'glutamate synthase
N7E70_RS12895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7E70_RS12910	COG1309	transcriptional regulator
N7E70_RS12915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_RS12945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS12950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS12975	COG0028	Belongs to the TPP enzyme family
N7E70_RS12980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_RS12985	COG2267	carboxylic ester hydrolase activity
N7E70_RS12990	COG1131	(ABC) transporter
N7E70_RS12995	COG0842	Transport permease protein
N7E70_RS13025	COG4106	trans-aconitate 2-methyltransferase activity
N7E70_RS13040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS13045	COG1522	sequence-specific DNA binding
N7E70_RS13055	COG1720	tRNA m6t6A37 methyltransferase activity
N7E70_RS13080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7E70_RS13120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N7E70_RS13140	COG0626	cystathionine gamma-synthase activity
N7E70_RS13145	COG2001	Belongs to the MraZ family
N7E70_RS13150	COG0275	rRNA processing
N7E70_RS13165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7E70_RS13175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7E70_RS13180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7E70_RS13190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7E70_RS13195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7E70_RS13200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N7E70_RS13205	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7E70_RS13210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7E70_RS13215	COG0849	cell division
N7E70_RS13220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7E70_RS13230	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_RS13260	COG0006	proline dipeptidase activity
N7E70_RS13265	COG2264	protein methyltransferase activity
N7E70_RS13270	COG1999	signal sequence binding
N7E70_RS13305	COG5002	protein histidine kinase activity
N7E70_RS13310	COG0745	RESPONSE REGULATOR receiver
N7E70_RS13325	COG0210	DNA helicase
N7E70_RS13350	COG0277	FAD linked oxidase domain protein
N7E70_RS13395	COG2814	Major facilitator Superfamily
N7E70_RS13400	COG3706	GGDEF domain
N7E70_RS13425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N7E70_RS13440	COG0330	HflC and HflK could
N7E70_RS13445	COG0330	HflC and HflK could
N7E70_RS13455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7E70_RS13465	COG3830	Belongs to the UPF0237 family
N7E70_RS13465	COG0560	Phosphoserine phosphatase
N7E70_RS13470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N7E70_RS13480	COG2267	carboxylic ester hydrolase activity
N7E70_RS13490	COG1132	(ABC) transporter
N7E70_RS13495	COG0028	Belongs to the TPP enzyme family
N7E70_RS13500	COG0440	acetolactate synthase activity
N7E70_RS13550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_RS13570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N7E70_RS13575	COG3158	transport of potassium into the cell
N7E70_RS13580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_RS13600	COG0583	DNA-binding transcription factor activity
N7E70_RS13605	COG1309	transcriptional regulator
N7E70_RS13610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N7E70_RS13640	COG1136	(ABC) transporter
N7E70_RS13640	COG0577	efflux transmembrane transporter activity
N7E70_RS13645	COG1136	(ABC) transporter
N7E70_RS13645	COG0577	efflux transmembrane transporter activity
N7E70_RS13655	COG0384	phenazine biosynthesis protein PhzF
N7E70_RS13675	COG0628	permease
N7E70_RS13695	COG1959	2 iron, 2 sulfur cluster binding
N7E70_RS13700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7E70_RS13705	COG4208	sulfate ABC transporter
N7E70_RS13715	COG4150	thiosulfate binding
N7E70_RS13720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N7E70_RS13725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N7E70_RS13730	COG1797	cobyrinic acid a,c-diamide synthase activity
N7E70_RS13740	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
N7E70_RS13800	COG3214	Protein conserved in bacteria
N7E70_RS13805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_RS13810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_RS13815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_RS13820	COG0649	NAD binding
N7E70_RS13825	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
N7E70_RS13830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N7E70_RS13835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7E70_RS13835	COG3743	rRNA binding
N7E70_RS13845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N7E70_RS13850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_RS13860	COG0713	ATP synthesis coupled electron transport
N7E70_RS13875	COG1007	ATP synthesis coupled electron transport
N7E70_RS13890	COG0346	lactoylglutathione lyase activity
N7E70_RS13900	COG0442	prolyl-tRNA aminoacylation
N7E70_RS13910	COG1136	(ABC) transporter
N7E70_RS13915	COG0442	prolyl-tRNA aminoacylation
N7E70_RS13925	COG0321	lipoyl(octanoyl) transferase activity
N7E70_RS13955	COG0789	Transcriptional regulator
N7E70_RS13960	COG2239	Acts as a magnesium transporter
N7E70_RS14040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_RS14070	COG0583	DNA-binding transcription factor activity
N7E70_RS14090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS14090	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS14100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS14105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N7E70_RS14105	COG3264	Mechanosensitive ion channel
N7E70_RS14130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7E70_RS14200	COG0583	DNA-binding transcription factor activity
N7E70_RS14225	COG0646	methionine synthase
N7E70_RS14225	COG1410	methionine synthase
N7E70_RS14245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7E70_RS14250	COG3932	Exopolysaccharide synthesis, ExoD
N7E70_RS14270	COG5012	cobalamin binding
N7E70_RS14275	COG5598	trimethylamine methyltransferase
N7E70_RS14285	COG2186	Transcriptional regulator
N7E70_RS14290	COG2807	transmembrane transport
N7E70_RS14300	COG2081	HI0933 family
N7E70_RS14315	COG2304	oxidoreductase activity
N7E70_RS14335	COG0646	methionine synthase
N7E70_RS14335	COG1410	methionine synthase
N7E70_RS14360	COG0006	proline dipeptidase activity
N7E70_RS14370	COG5598	trimethylamine methyltransferase
N7E70_RS14405	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS14415	COG1492	cobalamin metabolic process
N7E70_RS14440	COG4172	Belongs to the ABC transporter superfamily
N7E70_RS14445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS14450	COG0601	transmembrane transport
N7E70_RS14455	COG0747	negative chemotaxis
N7E70_RS14460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS14485	COG0243	molybdopterin cofactor binding
N7E70_RS14490	COG0437	4 iron, 4 sulfur cluster binding
N7E70_RS14495	COG3302	dmso reductase anchor subunit
N7E70_RS14500	COG1560	Kdo2-lipid A biosynthetic process
N7E70_RS14510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7E70_RS14520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7E70_RS14550	COG1522	sequence-specific DNA binding
N7E70_RS14580	COG1629	transport
N7E70_RS14590	COG3720	iron ion transport
N7E70_RS14600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS14605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N7E70_RS14610	COG1959	2 iron, 2 sulfur cluster binding
N7E70_RS14625	COG1309	transcriptional regulator
N7E70_RS14635	COG2733	membrane
N7E70_RS14685	COG2832	Protein of unknown function (DUF454)
N7E70_RS14690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7E70_RS14695	COG2205	protein histidine kinase activity
N7E70_RS14740	COG2205	protein histidine kinase activity
N7E70_RS14745	COG1525	nuclease
N7E70_RS14750	COG0625	glutathione transferase activity
N7E70_RS14755	COG1573	uracil-dna glycosylase
N7E70_RS14760	COG1522	sequence-specific DNA binding
N7E70_RS14770	COG2084	Dehydrogenase
N7E70_RS14790	COG1763	Mo-molybdopterin cofactor biosynthetic process
N7E70_RS14795	COG0746	molybdenum cofactor guanylyltransferase activity
N7E70_RS14820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7E70_RS14840	COG1846	Transcriptional regulator
N7E70_RS14845	COG0596	Alpha beta hydrolase
N7E70_RS14865	COG2989	Protein conserved in bacteria
N7E70_RS14890	COG0546	phosphoglycolate phosphatase activity
N7E70_RS14895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N7E70_RS14910	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
N7E70_RS14915	COG2199	diguanylate cyclase activity
N7E70_RS14920	COG2514	catechol 2,3-dioxygenase activity
N7E70_RS14930	COG0659	secondary active sulfate transmembrane transporter activity
N7E70_RS14935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7E70_RS14960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS14980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7E70_RS14980	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_RS14985	COG0746	molybdenum cofactor guanylyltransferase activity
N7E70_RS15020	COG0596	Alpha beta hydrolase
N7E70_RS15020	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS15060	COG2855	membrane
N7E70_RS15085	COG0850	regulation of cytokinetic process
N7E70_RS15090	COG2894	cell division
N7E70_RS15095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N7E70_RS15130	COG1607	acyl-coa hydrolase
N7E70_RS15135	COG0251	oxidation-reduction process
N7E70_RS15155	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_RS15205	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_RS15205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_RS15205	COG1042	CoA-binding domain protein
N7E70_RS15215	COG0459	protein refolding
N7E70_RS15230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7E70_RS15235	COG2235	arginine
N7E70_RS15265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7E70_RS15310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N7E70_RS15345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_RS15360	COG2205	protein histidine kinase activity
N7E70_RS15365	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS15390	COG0586	Pfam SNARE associated Golgi protein
N7E70_RS15405	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
N7E70_RS15415	COG1136	(ABC) transporter
N7E70_RS15430	COG5622	Protein required for attachment to host cells
N7E70_RS15435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7E70_RS15445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N7E70_RS15455	COG1546	Belongs to the CinA family
N7E70_RS15455	COG1058	Belongs to the CinA family
N7E70_RS15495	COG2267	carboxylic ester hydrolase activity
N7E70_RS15520	COG4191	Histidine kinase
N7E70_RS15525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7E70_RS15540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7E70_RS15545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_RS15560	COG1278	Cold shock
N7E70_RS15580	COG1024	Enoyl-CoA hydratase
N7E70_RS15625	COG0516	GMP reductase activity
N7E70_RS15625	COG0517	IMP dehydrogenase activity
N7E70_RS15630	COG3811	Belongs to the UPF0386 family
N7E70_RS15635	COG3850	Histidine kinase
N7E70_RS15635	COG5002	protein histidine kinase activity
N7E70_RS15640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7E70_RS15650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7E70_RS15655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_RS15680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N7E70_RS15685	COG0439	Biotin carboxylase
N7E70_RS15690	COG0511	ligase activity, forming carbon-carbon bonds
N7E70_RS15695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N7E70_RS15710	COG0436	Aminotransferase
N7E70_RS15735	COG2066	Belongs to the glutaminase family
N7E70_RS15900	COG0250	Participates in transcription elongation, termination and antitermination
N7E70_RS16065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_RS16080	COG0525	valine-tRNA ligase activity
N7E70_RS16095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
N7E70_RS16110	COG2233	PERMEase
N7E70_RS16125	COG0316	Belongs to the HesB IscA family
N7E70_RS16130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N7E70_RS16135	COG0018	arginyl-trna synthetase
N7E70_RS16150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7E70_RS16155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_RS16160	COG3842	ATPase activity
N7E70_RS16165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7E70_RS16170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7E70_RS16175	COG0805	protein transport
N7E70_RS16180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N7E70_RS16185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N7E70_RS16190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_RS16205	COG1862	Preprotein translocase
N7E70_RS16215	COG3737	Protein of unknown function (DUF498/DUF598)
N7E70_RS16235	COG0519	Catalyzes the synthesis of GMP from XMP
N7E70_RS16240	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N7E70_RS16285	COG0544	peptidyl-prolyl cis-trans isomerase activity
N7E70_RS16290	COG2003	Belongs to the UPF0758 family
N7E70_RS16295	COG0024	Methionine aminopeptidase
N7E70_RS16305	COG2824	Alkylphosphonate utilization operon protein PhnA
N7E70_RS16315	COG1609	Transcriptional regulator
N7E70_RS16325	COG1175	transmembrane transport
N7E70_RS16330	COG0395	ABC-type sugar transport system, permease component
N7E70_RS16345	COG3842	ATPase activity
N7E70_RS16365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7E70_RS16370	COG1116	anion transmembrane transporter activity
N7E70_RS16375	COG4149	molybdate abc transporter
N7E70_RS16425	COG3243	poly(R)-hydroxyalkanoic acid synthase
N7E70_RS16435	COG0436	Aminotransferase
N7E70_RS16445	COG1494	fructose-1,6-bisphosphatase
N7E70_RS16450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7E70_RS16455	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7E70_RS16460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7E70_RS16465	COG0302	gtp cyclohydrolase
N7E70_RS16475	COG0583	DNA-binding transcription factor activity
N7E70_RS16485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N7E70_RS16495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7E70_RS16510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS16515	COG2301	Belongs to the HpcH HpaI aldolase family
N7E70_RS16530	COG0187	DNA topoisomerase II activity
N7E70_RS16545	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7E70_RS16545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7E70_RS16550	COG0509	glycine decarboxylation via glycine cleavage system
N7E70_RS16555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS16565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7E70_RS16580	COG1671	Belongs to the UPF0178 family
N7E70_RS16590	COG2153	protein acetylation
N7E70_RS16595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N7E70_RS16605	COG4941	Belongs to the sigma-70 factor family
N7E70_RS16610	COG3795	YCII-related domain
N7E70_RS16630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7E70_RS16645	COG0475	glutathione-regulated potassium exporter activity
N7E70_RS16645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7E70_RS16660	COG3768	UPF0283 membrane protein
N7E70_RS16665	COG3106	COG3106 Predicted ATPase
N7E70_RS16710	COG0513	Belongs to the DEAD box helicase family
N7E70_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS16730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7E70_RS16735	COG2897	thiosulfate sulfurtransferase activity
N7E70_RS16750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7E70_RS16765	COG0686	Belongs to the AlaDH PNT family
N7E70_RS16770	COG1522	sequence-specific DNA binding
N7E70_RS16775	COG0737	Belongs to the 5'-nucleotidase family
N7E70_RS16785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N7E70_RS16795	COG4957	zinc ion binding
N7E70_RS16800	COG1530	ribonuclease E activity
N7E70_RS16805	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7E70_RS16810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_RS16835	COG2885	chlorophyll binding
N7E70_RS16845	COG0513	Belongs to the DEAD box helicase family
N7E70_RS16850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7E70_RS16860	COG3706	GGDEF domain
N7E70_RS16880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7E70_RS16890	COG1414	Transcriptional regulator
N7E70_RS16895	COG3960	tartronate-semialdehyde synthase activity
N7E70_RS16900	COG3622	Belongs to the hyi family
N7E70_RS16905	COG2084	Dehydrogenase
N7E70_RS16925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7E70_RS16940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7E70_RS16965	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7E70_RS16975	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N7E70_RS16980	COG0081	regulation of translation
N7E70_RS16985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N7E70_RS16990	COG0222	ribosome binding
N7E70_RS16995	COG0085	RNA polymerase activity
N7E70_RS17000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N7E70_RS17010	COG0531	amino acid
N7E70_RS17020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N7E70_RS17025	COG0049	tRNA binding
N7E70_RS17030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7E70_RS17035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7E70_RS17040	COG0051	transcription antitermination factor activity, RNA binding
N7E70_RS17045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N7E70_RS17050	COG0088	Forms part of the polypeptide exit tunnel
N7E70_RS17055	COG0089	rRNA binding
N7E70_RS17060	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N7E70_RS17065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N7E70_RS17070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N7E70_RS17075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N7E70_RS17080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N7E70_RS17085	COG0255	Belongs to the universal ribosomal protein uL29 family
N7E70_RS17090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N7E70_RS17095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N7E70_RS17100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N7E70_RS17105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N7E70_RS17110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7E70_RS17115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N7E70_RS17120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N7E70_RS17125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N7E70_RS17130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N7E70_RS17135	COG1841	ribosomal large subunit assembly
N7E70_RS17140	COG0200	Binds to the 23S rRNA
N7E70_RS17150	COG0563	adenylate kinase activity
N7E70_RS17155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N7E70_RS17160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N7E70_RS17165	COG0202	RNA polymerase activity
N7E70_RS17170	COG0203	ribosomal protein L17
N7E70_RS17180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7E70_RS17185	COG0640	Transcriptional regulator
N7E70_RS17210	COG2826	transposase and inactivated derivatives, IS30 family
N7E70_RS17215	COG0321	lipoyl(octanoyl) transferase activity
N7E70_RS17215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N7E70_RS17220	COG0084	hydrolase, TatD family'
N7E70_RS17225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_RS17235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7E70_RS17240	COG1686	Belongs to the peptidase S11 family
N7E70_RS17280	COG2948	multi-organism process
N7E70_RS17295	COG3846	protein secretion by the type IV secretion system
N7E70_RS17310	COG3451	type IV secretory pathway VirB4
N7E70_RS17325	COG4962	Type ii secretion system protein e
N7E70_RS17345	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_RS17365	COG0741	lytic transglycosylase activity
N7E70_RS17485	COG0708	Exodeoxyribonuclease III
N7E70_RS17500	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N7E70_RS17515	COG0583	DNA-binding transcription factor activity
N7E70_RS17520	COG0601	transmembrane transport
N7E70_RS17525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS17530	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS17535	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS17540	COG4166	transmembrane transport
N7E70_RS17680	COG2885	chlorophyll binding
N7E70_RS17700	COG0739	heme binding
N7E70_RS17710	COG0861	Integral membrane protein TerC family
N7E70_RS17715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_RS17720	COG2814	Major facilitator Superfamily
N7E70_RS17755	COG1024	Enoyl-CoA hydratase
N7E70_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17775	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17790	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17825	COG0183	Belongs to the thiolase family
N7E70_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17840	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS17855	COG1024	Enoyl-CoA hydratase
N7E70_RS17855	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_RS17860	COG0604	alcohol dehydrogenase
N7E70_RS17865	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17870	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS17880	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17920	COG0657	acetylesterase activity
N7E70_RS17930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_RS17935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS17955	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS17960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7E70_RS17965	COG0183	Belongs to the thiolase family
N7E70_RS17970	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS17975	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS17980	COG1024	Enoyl-CoA hydratase
N7E70_RS17985	COG0667	Aldo Keto reductase
N7E70_RS17990	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N7E70_RS18025	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS18030	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS18035	COG3845	ABC transporter
N7E70_RS18045	COG1183	phosphatidylcholine synthase activity
N7E70_RS18050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_RS18055	COG0679	Auxin Efflux Carrier
N7E70_RS18070	COG4166	transmembrane transport
N7E70_RS18085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7E70_RS18090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N7E70_RS18095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7E70_RS18105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7E70_RS18110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N7E70_RS18115	COG0785	Cytochrome C biogenesis protein
N7E70_RS18315	COG4974	Belongs to the 'phage' integrase family
N7E70_RS18340	COG0861	Integral membrane protein TerC family
N7E70_RS18365	COG2308	Evidence 4 Homologs of previously reported genes of
N7E70_RS18380	COG0488	(ABC) transporter
N7E70_RS18395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7E70_RS18400	COG0343	queuine tRNA-ribosyltransferase activity
N7E70_RS18405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N7E70_RS18425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N7E70_RS18435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7E70_RS18440	COG2095	MarC family integral membrane protein
N7E70_RS18455	COG0629	single-stranded DNA binding
N7E70_RS18465	COG2188	Transcriptional regulator
N7E70_RS18475	COG0395	ABC-type sugar transport system, permease component
N7E70_RS18495	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS18505	COG1794	racemase activity, acting on amino acids and derivatives
N7E70_RS18510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7E70_RS18540	COG1309	transcriptional regulator
N7E70_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS18550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N7E70_RS18550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N7E70_RS18555	COG0347	Belongs to the P(II) protein family
N7E70_RS18560	COG0174	glutamine synthetase
N7E70_RS18590	COG0174	glutamine synthetase
N7E70_RS18600	COG0697	spore germination
N7E70_RS18615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7E70_RS18620	COG3956	TIGRFAM MazG family protein
N7E70_RS18625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7E70_RS18630	COG1923	regulation of RNA biosynthetic process
N7E70_RS18635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS18640	COG0569	domain protein
N7E70_RS18645	COG2204	response regulator
N7E70_RS18650	COG5000	phosphorelay sensor kinase activity
N7E70_RS18655	COG2204	response regulator
N7E70_RS18660	COG3852	Histidine kinase
N7E70_RS18670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N7E70_RS18670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N7E70_RS18675	COG1058	Belongs to the CinA family
N7E70_RS18675	COG1546	Belongs to the CinA family
N7E70_RS18685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7E70_RS18695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7E70_RS18700	COG0456	acetyltransferase
N7E70_RS18700	COG1214	PFAM Peptidase M22, glycoprotease
N7E70_RS18710	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS18715	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS18715	COG0022	dehydrogenase e1 component
N7E70_RS18720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7E70_RS18725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7E70_RS18730	COG0148	phosphopyruvate hydratase activity
N7E70_RS18745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
N7E70_RS18760	COG0504	CTP synthase activity
N7E70_RS18775	COG0149	triose-phosphate isomerase activity
N7E70_RS18785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N7E70_RS18790	COG0134	indole-3-glycerol-phosphate synthase activity
N7E70_RS18795	COG0315	cyclic pyranopterin monophosphate synthase activity
N7E70_RS18800	COG0303	'Molybdopterin
N7E70_RS18805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7E70_RS18815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_RS18820	COG0372	Belongs to the citrate synthase family
N7E70_RS18825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_RS18835	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_RS18840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7E70_RS18845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_RS18850	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_RS18855	COG0750	zinc metalloprotease
N7E70_RS18865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7E70_RS18870	COG0233	cytoplasmic translational termination
N7E70_RS18875	COG0528	UMP kinase activity
N7E70_RS18880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N7E70_RS18885	COG0052	Belongs to the universal ribosomal protein uS2 family
N7E70_RS18920	COG0537	adenosine 5'-monophosphoramidase activity
N7E70_RS18945	COG3706	GGDEF domain
N7E70_RS18955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N7E70_RS18965	COG1686	Belongs to the peptidase S11 family
N7E70_RS18970	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N7E70_RS18985	COG1760	l-serine dehydratase
N7E70_RS19000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N7E70_RS19005	COG0154	amidase activity
N7E70_RS19010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7E70_RS19020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7E70_RS19025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7E70_RS19035	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS19040	COG0540	Belongs to the ATCase OTCase family
N7E70_RS19045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7E70_RS19050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N7E70_RS19055	COG0758	DNA mediated transformation
N7E70_RS19060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7E70_RS19065	COG0557	exoribonuclease II activity
N7E70_RS19085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N7E70_RS19095	COG0784	Response regulator, receiver
N7E70_RS19110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7E70_RS19115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N7E70_RS19120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7E70_RS19130	COG0492	ferredoxin-NADP+ reductase activity
N7E70_RS19135	COG0633	Ferredoxin
N7E70_RS19150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N7E70_RS19150	COG3218	ABC-type transport auxiliary lipoprotein component
N7E70_RS19160	COG1127	ABC transporter
N7E70_RS19170	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS19190	COG0280	phosphate acetyltransferase
N7E70_RS19190	COG0281	malic enzyme
N7E70_RS19200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_RS19205	COG1132	(ABC) transporter
N7E70_RS19210	COG0640	Transcriptional regulator
N7E70_RS19220	COG0740	serine-type endopeptidase activity
N7E70_RS19260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N7E70_RS19265	COG3384	dioxygenase
N7E70_RS19275	COG0519	Catalyzes the synthesis of GMP from XMP
N7E70_RS19295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N7E70_RS19300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7E70_RS19305	COG0047	phosphoribosylformylglycinamidine synthase activity
N7E70_RS19320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS19325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7E70_RS19340	COG2226	methyltransferase
N7E70_RS19350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N7E70_RS19355	COG2814	Major facilitator Superfamily
N7E70_RS19360	COG0037	tRNA processing
N7E70_RS19365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N7E70_RS19375	COG1733	regulation of RNA biosynthetic process
N7E70_RS19380	COG0702	epimerase
N7E70_RS19390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7E70_RS19405	COG0538	isocitrate dehydrogenase activity
N7E70_RS19420	COG0346	lactoylglutathione lyase activity
N7E70_RS19425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7E70_RS19430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N7E70_RS19440	COG2313	pseudouridylate synthase activity
N7E70_RS19455	COG0316	Belongs to the HesB IscA family
N7E70_RS19470	COG2151	metal-sulfur cluster biosynthetic enzyme
N7E70_RS19475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7E70_RS19480	COG0719	Fe-S assembly protein
N7E70_RS19485	COG0396	ATPase activity
N7E70_RS19495	COG0719	Fe-S assembly protein
N7E70_RS19505	COG2945	thiolester hydrolase activity
N7E70_RS19535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7E70_RS19545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7E70_RS19550	COG0739	heme binding
N7E70_RS19580	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
N7E70_RS19590	COG0411	ABC transporter
N7E70_RS19600	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS19620	COG1917	Cupin 2, conserved barrel domain protein
N7E70_RS19625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS19635	COG0583	DNA-binding transcription factor activity
N7E70_RS19655	COG0583	DNA-binding transcription factor activity
N7E70_RS19675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N7E70_RS19685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N7E70_RS19690	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_RS19700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_RS19705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_RS19720	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS19725	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS19730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS19735	COG0601	transmembrane transport
N7E70_RS19740	COG1396	sequence-specific DNA binding
N7E70_RS19745	COG0747	negative chemotaxis
N7E70_RS19765	COG0776	regulation of translation
N7E70_RS19775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N7E70_RS19780	COG0740	serine-type endopeptidase activity
N7E70_RS19825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N7E70_RS19830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7E70_RS19845	COG0584	glycerophosphoryl diester phosphodiesterase
N7E70_RS19850	COG0010	Belongs to the arginase family
N7E70_RS19865	COG1612	heme a metabolic process
N7E70_RS19895	COG0297	glycogen (starch) synthase activity
N7E70_RS19930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7E70_RS19945	COG0776	regulation of translation
N7E70_RS19950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_RS19955	COG0416	fatty acid biosynthetic process
N7E70_RS19970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_RS19975	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
N7E70_RS19990	COG1174	glycine betaine transport
N7E70_RS19995	COG1125	glycine betaine transport
N7E70_RS20000	COG1174	glycine betaine transport
N7E70_RS20005	COG1732	Glycine betaine
N7E70_RS20010	COG2814	Major facilitator Superfamily
N7E70_RS20015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_RS20020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7E70_RS20030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7E70_RS20030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7E70_RS20035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N7E70_RS20040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7E70_RS20050	COG2989	Protein conserved in bacteria
N7E70_RS20070	COG0113	porphobilinogen synthase activity
N7E70_RS20080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
N7E70_RS20090	COG0628	permease
N7E70_RS20095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7E70_RS20105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N7E70_RS20120	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N7E70_RS20145	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N7E70_RS20195	COG2235	arginine
N7E70_RS20265	COG0730	response to heat
N7E70_RS20275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS20285	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS20290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7E70_RS20295	COG1349	DNA-binding transcription factor activity
N7E70_RS20310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7E70_RS20315	COG0583	DNA-binding transcription factor activity
N7E70_RS20325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS20330	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_RS20335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7E70_RS20340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7E70_RS20345	COG2188	Transcriptional regulator
N7E70_RS20370	COG0583	DNA-binding transcription factor activity
N7E70_RS20375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS20400	COG1653	transport
N7E70_RS20425	COG3842	ATPase activity
N7E70_RS20430	COG2252	PERMEase
N7E70_RS20445	COG3842	ATPase activity
N7E70_RS20455	COG0395	ABC-type sugar transport system, permease component
N7E70_RS20470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7E70_RS20480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7E70_RS20485	COG1132	(ABC) transporter
N7E70_RS20490	COG3459	Glycosyltransferase 36 associated
N7E70_RS20505	COG3314	Sporulation integral membrane protein YlbJ
N7E70_RS20510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N7E70_RS20520	COG2986	histidine ammonia-lyase
N7E70_RS20525	COG1228	amidohydrolase
N7E70_RS20550	COG0251	oxidation-reduction process
N7E70_RS20560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_RS20565	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7E70_RS20575	COG0523	cobalamin synthesis protein
N7E70_RS20595	COG1234	tRNA 3'-trailer cleavage
N7E70_RS20605	COG1063	alcohol dehydrogenase
N7E70_RS20620	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS20630	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS20640	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS20640	COG1902	pentaerythritol trinitrate reductase activity
N7E70_RS20645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N7E70_RS20660	COG5598	trimethylamine methyltransferase
N7E70_RS20665	COG0583	DNA-binding transcription factor activity
N7E70_RS20670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7E70_RS20690	COG1663	tetraacyldisaccharide 4'-kinase activity
N7E70_RS20695	COG1519	Transferase
N7E70_RS20710	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_RS20715	COG0312	modulator of DNA gyrase
N7E70_RS20730	COG0612	Peptidase, M16
N7E70_RS20735	COG0612	Peptidase, M16
N7E70_RS20740	COG0742	ribosomal rna small subunit methyltransferase
N7E70_RS20745	COG1187	pseudouridine synthase activity
N7E70_RS20750	COG0590	tRNA wobble adenosine to inosine editing
N7E70_RS20760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7E70_RS20775	COG0196	riboflavin kinase activity
N7E70_RS20790	COG2814	Major facilitator Superfamily
N7E70_RS20800	COG1846	Transcriptional regulator
N7E70_RS20805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7E70_RS20805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N7E70_RS20815	COG0459	protein refolding
N7E70_RS20845	COG3237	CsbD-like
N7E70_RS20860	COG0114	fumarate hydratase activity
N7E70_RS20865	COG2259	Doxx family
N7E70_RS20875	COG0248	Ppx GppA phosphatase
N7E70_RS20880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N7E70_RS20890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_RS20900	COG1126	abc transporter atp-binding protein
N7E70_RS20905	COG0765	amino acid transport
N7E70_RS20910	COG4597	amino acid ABC transporter
N7E70_RS20915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS20925	COG0626	cystathionine gamma-synthase activity
N7E70_RS20935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_RS20945	COG3852	Histidine kinase
N7E70_RS20990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_RS21000	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_RS21170	COG3657	addiction module killer protein
N7E70_RS21175	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_RS21200	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS21210	COG0583	DNA-binding transcription factor activity
N7E70_RS21215	COG2207	Transcriptional regulator
N7E70_RS21225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS21235	COG0747	negative chemotaxis
N7E70_RS21240	COG0601	transmembrane transport
N7E70_RS21245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS21250	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS21260	COG2207	Transcriptional regulator
N7E70_RS21280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N7E70_RS21290	COG5425	PFAM Usg family protein
N7E70_RS21300	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_RS21305	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_RS21325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7E70_RS21330	COG0454	-acetyltransferase
N7E70_RS21335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_RS21340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_RS21345	COG0745	RESPONSE REGULATOR receiver
N7E70_RS21350	COG5002	protein histidine kinase activity
N7E70_RS21360	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N7E70_RS21410	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS21415	COG1129	ABC transporter
N7E70_RS21420	COG0702	epimerase
N7E70_RS21430	COG2186	Transcriptional regulator
N7E70_RS21445	COG2186	Transcriptional regulator
N7E70_RS21455	COG1136	(ABC) transporter
N7E70_RS21530	COG0210	DNA helicase
N7E70_RS21535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_RS21550	COG0583	DNA-binding transcription factor activity
N7E70_RS21560	COG0747	negative chemotaxis
N7E70_RS21570	COG3265	gluconokinase activity
N7E70_RS21575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_RS21585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_RS21590	COG2084	Dehydrogenase
N7E70_RS21635	COG0464	growth
N7E70_RS21680	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS21685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS21700	COG0747	negative chemotaxis
N7E70_RS21705	COG2186	Transcriptional regulator
N7E70_RS21715	COG1473	amidohydrolase
N7E70_RS21725	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N7E70_RS21735	COG3474	cytochrome
N7E70_RS21850	COG0210	DNA helicase
N7E70_RS21890	COG0640	Transcriptional regulator
N7E70_RS21895	COG0798	PFAM Bile acid sodium symporter
N7E70_RS21905	COG0431	NADPH-dependent FMN reductase
N7E70_RS21930	COG0753	catalase activity
N7E70_RS21975	COG1278	Cold shock
N7E70_RS21985	COG0784	Response regulator, receiver
N7E70_RS21985	COG4191	Histidine kinase
N7E70_RS21995	COG3685	Protein conserved in bacteria
N7E70_RS22000	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS22075	COG2827	Endonuclease containing a URI domain
N7E70_RS22115	COG0784	Response regulator, receiver
N7E70_RS22115	COG2205	protein histidine kinase activity
N7E70_RS22120	COG2197	response regulator
N7E70_RS22125	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS22140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS22150	COG0747	negative chemotaxis
N7E70_RS22180	COG0628	permease
N7E70_RS22185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7E70_RS22190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N7E70_RS22195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7E70_RS22225	COG0583	DNA-binding transcription factor activity
N7E70_RS22235	COG1024	Enoyl-CoA hydratase
N7E70_RS22240	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS22245	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS22250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS22275	COG0583	DNA-binding transcription factor activity
N7E70_RS22280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS22285	COG0765	amino acid transport
N7E70_RS22295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N7E70_RS22310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7E70_RS22340	COG0243	molybdopterin cofactor binding
N7E70_RS22345	COG0488	(ABC) transporter
N7E70_RS22350	COG2211	Major facilitator Superfamily
N7E70_RS22370	COG0105	UTP biosynthetic process
N7E70_RS22380	COG0314	molybdopterin synthase activity
N7E70_RS22395	COG0322	excinuclease ABC activity
N7E70_RS22440	COG0625	glutathione transferase activity
N7E70_RS22455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N7E70_RS22480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7E70_RS22505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N7E70_RS22510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7E70_RS22535	COG0194	GDP metabolic process
N7E70_RS22540	COG1561	YicC-like family, N-terminal region
N7E70_RS22545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7E70_RS22550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7E70_RS22555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7E70_RS22565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7E70_RS22570	COG1368	sulfuric ester hydrolase activity
N7E70_RS22575	COG0360	Binds together with S18 to 16S ribosomal RNA
N7E70_RS22585	COG0359	binds to the 23S rRNA
N7E70_RS22590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N7E70_RS22595	COG1742	UPF0060 membrane protein
N7E70_RS22600	COG3468	outer membrane autotransporter barrel domain protein
N7E70_RS22605	COG0305	Participates in initiation and elongation during chromosome replication
N7E70_RS22620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_RS22630	COG4221	oxidoreductase activity
N7E70_RS22635	COG3273	potassium ion transport
N7E70_RS22635	COG0471	metal ion transport
N7E70_RS22660	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS22660	COG0204	Acyl-transferase
N7E70_RS22670	COG0688	phosphatidylethanolamine metabolic process
N7E70_RS22675	COG5265	(ABC) transporter
N7E70_RS22685	COG1652	LysM domain
N7E70_RS22700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7E70_RS22730	COG2852	Protein conserved in bacteria
N7E70_RS22735	COG0215	cysteine-tRNA ligase activity
N7E70_RS22775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7E70_RS22785	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
N7E70_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS22820	COG0640	Transcriptional regulator
N7E70_RS22855	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
N7E70_RS22885	COG1381	Involved in DNA repair and RecF pathway recombination
N7E70_RS22890	COG0477	Major facilitator Superfamily
N7E70_RS22910	COG2814	Major facilitator Superfamily
N7E70_RS22930	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS22960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS22975	COG1280	lysine exporter protein (LysE YggA)
N7E70_RS23020	COG4191	Histidine kinase
N7E70_RS23020	COG0784	Response regulator, receiver
N7E70_RS23030	COG0300	oxidoreductase activity
N7E70_RS23045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7E70_RS23050	COG0571	ribonuclease III activity
N7E70_RS23055	COG0681	Belongs to the peptidase S26 family
N7E70_RS23060	COG0736	holo-[acyl-carrier-protein] synthase activity
N7E70_RS23065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N7E70_RS23075	COG1758	RNA polymerase activity
N7E70_RS23100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N7E70_RS23105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS23110	COG0741	lytic transglycosylase activity
N7E70_RS23135	COG4974	Belongs to the 'phage' integrase family
N7E70_RS23150	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
N7E70_RS23155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_RS23165	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS23185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7E70_RS23190	COG4770	biotin carboxylase activity
N7E70_RS23205	COG0450	alkyl hydroperoxide reductase
N7E70_RS23225	COG0625	glutathione transferase activity
N7E70_RS23235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7E70_RS23265	COG1573	uracil-dna glycosylase
N7E70_RS23280	COG0438	transferase activity, transferring glycosyl groups
N7E70_RS23295	COG0308	aminopeptidase N
N7E70_RS23300	COG2205	protein histidine kinase activity
N7E70_RS23300	COG2202	Pas domain
N7E70_RS23305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS23320	COG2205	protein histidine kinase activity
N7E70_RS23325	COG0745	RESPONSE REGULATOR receiver
N7E70_RS23330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7E70_RS23335	COG3088	subunit of a heme lyase
N7E70_RS23340	COG1138	Cytochrome C-type biogenesis protein
N7E70_RS23345	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N7E70_RS23350	COG4235	cytochrome complex assembly
N7E70_RS23380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_RS23415	COG2205	protein histidine kinase activity
N7E70_RS23425	COG2166	iron-sulfur cluster assembly
N7E70_RS23430	COG4957	zinc ion binding
N7E70_RS23435	COG1320	monovalent cation:proton antiporter activity
N7E70_RS23440	COG2212	antiporter activity
N7E70_RS23445	COG1863	multisubunit Na H antiporter MnhE subunit
N7E70_RS23450	COG0651	ATP synthesis coupled electron transport
N7E70_RS23455	COG1006	Multisubunit Na H antiporter MnhC subunit
N7E70_RS23460	COG2111	Na H antiporter
N7E70_RS23465	COG2111	Na H antiporter
N7E70_RS23465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7E70_RS23480	COG2010	Cytochrome c
N7E70_RS23485	COG3909	cytochrome
N7E70_RS23490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7E70_RS23495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS23505	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS23510	COG0433	COG0433 Predicted ATPase
N7E70_RS23515	COG2336	PFAM SpoVT AbrB
N7E70_RS23520	COG3654	unkown
N7E70_RS23525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_RS23535	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS23540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_RS23545	COG1309	transcriptional regulator
N7E70_RS23550	COG3119	arylsulfatase activity
N7E70_RS23560	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N7E70_RS23565	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS23575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7E70_RS23595	COG4172	Belongs to the ABC transporter superfamily
N7E70_RS23600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS23605	COG0601	transmembrane transport
N7E70_RS23615	COG0366	Alpha amylase catalytic
N7E70_RS23620	COG1523	belongs to the glycosyl hydrolase 13 family
N7E70_RS23625	COG0033	Phosphoglucomutase
N7E70_RS23630	COG0297	glycogen (starch) synthase activity
N7E70_RS23635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7E70_RS23640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N7E70_RS23645	COG0058	SHG alpha-glucan phosphorylase activity
N7E70_RS23665	COG1940	carbohydrate kinase activity
N7E70_RS23685	COG1218	3'(2'),5'-bisphosphate nucleotidase
N7E70_RS23695	COG0175	sulfate reduction
N7E70_RS23725	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS23740	COG0574	Belongs to the PEP-utilizing enzyme family
N7E70_RS23740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7E70_RS23765	COG0829	nickel cation binding
N7E70_RS23770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_RS23775	COG0804	urea catabolic process
N7E70_RS23780	COG0831	urea catabolic process
N7E70_RS23780	COG0832	Belongs to the urease beta subunit family
N7E70_RS23785	COG0830	nickel cation binding
N7E70_RS23830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS23840	COG0010	Belongs to the arginase family
N7E70_RS23890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_RS23895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_RS23905	COG1196	nuclear chromosome segregation
N7E70_RS23910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7E70_RS23920	COG1194	a g-specific adenine glycosylase
N7E70_RS23925	COG1011	Hydrolase
N7E70_RS23930	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N7E70_RS23935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_RS23950	COG0612	Peptidase, M16
N7E70_RS23955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_RS23965	COG1678	Uncharacterized ACR, COG1678
N7E70_RS23975	COG0678	peroxiredoxin activity
N7E70_RS23980	COG0328	RNA-DNA hybrid ribonuclease activity
N7E70_RS23985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7E70_RS23990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N7E70_RS23995	COG3346	SURF1 family
N7E70_RS24015	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
N7E70_RS24025	COG0109	protoheme IX farnesyltransferase activity
N7E70_RS24030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7E70_RS24035	COG1565	acr, cog1565
N7E70_RS24035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7E70_RS24055	COG0312	modulator of DNA gyrase
N7E70_RS24065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7E70_RS24075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N7E70_RS24080	COG1741	Belongs to the pirin family
N7E70_RS24090	COG1722	exodeoxyribonuclease VII activity
N7E70_RS24095	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7E70_RS24100	COG1309	transcriptional regulator
N7E70_RS24120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7E70_RS24120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7E70_RS24125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N7E70_RS24135	COG0406	alpha-ribazole phosphatase activity
N7E70_RS24140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7E70_RS24155	COG0259	pyridoxamine-phosphate oxidase activity
N7E70_RS24165	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS24175	COG0151	Belongs to the GarS family
N7E70_RS24180	COG4115	mRNA cleavage
N7E70_RS24205	COG0009	L-threonylcarbamoyladenylate synthase
N7E70_RS24215	COG0751	glycine-tRNA ligase activity
N7E70_RS24225	COG0752	glycyl-tRNA synthetase alpha subunit
N7E70_RS24235	COG0142	geranyltranstransferase activity
N7E70_RS24260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N7E70_RS24265	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7E70_RS24280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7E70_RS24290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7E70_RS24295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7E70_RS24300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7E70_RS24305	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_RS24320	COG1160	GTP binding
N7E70_RS24335	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N7E70_RS24340	COG3788	relative of glutathione S-transferase, MAPEG superfamily
N7E70_RS24350	COG0583	DNA-binding transcription factor activity
N7E70_RS24355	COG1393	Belongs to the ArsC family
N7E70_RS24360	COG0251	oxidation-reduction process
N7E70_RS24370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS24390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_RS24400	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS24415	COG0494	nUDIX hydrolase
N7E70_RS24420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS24435	COG0657	acetylesterase activity
N7E70_RS24445	COG0583	DNA-binding transcription factor activity
N7E70_RS24450	COG0242	peptide deformylase activity
N7E70_RS24470	COG4172	Belongs to the ABC transporter superfamily
N7E70_RS24475	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS24480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS24485	COG0601	transmembrane transport
N7E70_RS24535	COG0840	transmembrane signaling receptor activity
N7E70_RS24540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_RS24550	COG3386	PFAM SMP-30 Gluconolaconase
N7E70_RS24555	COG0800	Aldolase
N7E70_RS24560	COG3734	2-keto-3-deoxy-galactonokinase
N7E70_RS24565	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS24570	COG2017	converts alpha-aldose to the beta-anomer
N7E70_RS24580	COG1129	ABC transporter
N7E70_RS24590	COG2186	Transcriptional regulator
N7E70_RS24595	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS24615	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS24620	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS24625	COG3845	ABC transporter
N7E70_RS24630	COG0583	DNA-binding transcription factor activity
N7E70_RS24640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7E70_RS24645	COG0163	prenyltransferase activity
N7E70_RS24665	COG0523	cobalamin synthesis protein
N7E70_RS24670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7E70_RS24685	COG2233	PERMEase
N7E70_RS24690	COG0583	DNA-binding transcription factor activity
N7E70_RS24705	COG0431	NADPH-dependent FMN reductase
N7E70_RS24745	COG1126	abc transporter atp-binding protein
N7E70_RS24755	COG1959	2 iron, 2 sulfur cluster binding
N7E70_RS24760	COG2346	COG2346, Truncated hemoglobins
N7E70_RS24775	COG3278	Belongs to the heme-copper respiratory oxidase family
N7E70_RS24790	COG2010	Cytochrome c
N7E70_RS24830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_RS24850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N7E70_RS24860	COG0826	peptidase U32
N7E70_RS24870	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7E70_RS24880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7E70_RS24885	COG2186	Transcriptional regulator
N7E70_RS24910	COG2151	metal-sulfur cluster biosynthetic enzyme
N7E70_RS24975	COG3794	PFAM blue (type 1) copper domain protein
N7E70_RS24995	COG2814	Major facilitator Superfamily
N7E70_RS25015	COG3005	denitrification pathway
N7E70_RS25040	COG4459	periplasmic nitrate reductase
N7E70_RS25045	COG1959	2 iron, 2 sulfur cluster binding
N7E70_RS25070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_RS25085	COG0714	Associated with various cellular activities
N7E70_RS25090	COG3256	nitric oxide reductase
N7E70_RS25105	COG1845	cytochrome c oxidase, subunit III
N7E70_RS25130	COG4521	taurine ABC transporter
N7E70_RS25160	COG5489	Protein of unknown function (DUF736)
N7E70_RS25170	COG3916	Acyl-homoserine-lactone synthase
N7E70_RS25175	COG2197	response regulator
N7E70_RS25185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7E70_RS25190	COG1476	TRANSCRIPTIONal
N7E70_RS25245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS25250	COG0765	amino acid transport
N7E70_RS25255	COG0765	amino acid transport
N7E70_RS25260	COG1126	abc transporter atp-binding protein
N7E70_RS25265	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_RS25305	COG0741	lytic transglycosylase activity
N7E70_RS25310	COG2433	Pfam Transposase IS66
N7E70_RS25315	COG3436	PFAM IS66 Orf2 family protein
N7E70_RS25340	COG1522	sequence-specific DNA binding
N7E70_RS25350	COG4962	Type ii secretion system protein e
N7E70_RS25355	COG3838	Conjugal transfer protein Trbc
N7E70_RS25365	COG3451	type IV secretory pathway VirB4
N7E70_RS25380	COG3846	protein secretion by the type IV secretion system
N7E70_RS25395	COG2948	multi-organism process
N7E70_RS25410	COG3550	peptidyl-serine autophosphorylation
N7E70_RS25415	COG1396	sequence-specific DNA binding
N7E70_RS25450	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N7E70_RS25455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7E70_RS25455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_RS25460	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
N7E70_RS25465	COG0583	DNA-binding transcription factor activity
N7E70_RS25470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7E70_RS25475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N7E70_RS25480	COG0124	histidyl-tRNA synthetase
N7E70_RS25495	COG2818	Glycosylase
N7E70_RS25500	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS25505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7E70_RS25510	COG1388	LysM domain
N7E70_RS25510	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_RS25520	COG0247	lactate metabolic process
N7E70_RS25535	COG2852	Protein conserved in bacteria
N7E70_RS25545	COG0277	FAD linked oxidase domain protein
N7E70_RS25555	COG2186	Transcriptional regulator
N7E70_RS25560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7E70_RS25625	COG0583	DNA-binding transcription factor activity
N7E70_RS25630	COG1570	exodeoxyribonuclease VII activity
N7E70_RS25645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_RS25650	COG1178	ABC-type Fe3 transport system permease component
N7E70_RS25655	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_RS25660	COG2205	protein histidine kinase activity
N7E70_RS25665	COG5490	Phasin protein
N7E70_RS25690	COG1177	transmembrane transport
N7E70_RS25695	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS25700	COG3842	ATPase activity
N7E70_RS25715	COG0431	NADPH-dependent FMN reductase
N7E70_RS25720	COG2814	Major facilitator Superfamily
N7E70_RS25730	COG5001	Diguanylate cyclase
N7E70_RS25730	COG3300	MHYT domain
N7E70_RS25740	COG2224	Isocitrate lyase
N7E70_RS25760	COG0174	glutamine synthetase
N7E70_RS25765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS25775	COG0745	RESPONSE REGULATOR receiver
N7E70_RS25790	COG3794	PFAM blue (type 1) copper domain protein
N7E70_RS25815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N7E70_RS25820	COG0363	glucosamine-6-phosphate deaminase activity
N7E70_RS25825	COG0129	dihydroxy-acid dehydratase activity
N7E70_RS25835	COG0488	(ABC) transporter
N7E70_RS25850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7E70_RS25870	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N7E70_RS25905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N7E70_RS25910	COG4149	molybdate abc transporter
N7E70_RS25915	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7E70_RS25920	COG0730	response to heat
N7E70_RS25925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7E70_RS25930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7E70_RS25940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_RS25960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7E70_RS25970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7E70_RS25975	COG5328	Belongs to the UPF0262 family
N7E70_RS25985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N7E70_RS25990	COG0424	maF-like protein
N7E70_RS25995	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N7E70_RS26005	COG3300	MHYT domain
N7E70_RS26005	COG5001	Diguanylate cyclase
N7E70_RS26015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS26020	COG2186	Transcriptional regulator
N7E70_RS26050	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N7E70_RS26055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS26085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS26095	COG0251	oxidation-reduction process
N7E70_RS26105	COG0765	amino acid transport
N7E70_RS26110	COG0765	amino acid transport
N7E70_RS26130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7E70_RS26135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS26140	COG1120	ATPase activity
N7E70_RS26145	COG3585	molybdate ion transport
N7E70_RS26160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS26165	COG4215	(ABC) transporter
N7E70_RS26170	COG0765	amino acid transport
N7E70_RS26175	COG3457	Alanine racemase
N7E70_RS26180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS26190	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_RS26195	COG0436	Aminotransferase
N7E70_RS26200	COG1970	mechanosensitive ion channel activity
N7E70_RS26205	COG0784	Response regulator, receiver
N7E70_RS26205	COG2198	Histidine kinase
N7E70_RS26205	COG2205	protein histidine kinase activity
N7E70_RS26225	COG0167	dihydroorotate dehydrogenase activity
N7E70_RS26235	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7E70_RS26245	COG5001	Diguanylate cyclase
N7E70_RS26255	COG0463	Glycosyl transferase, family 2
N7E70_RS26270	COG0717	Belongs to the dCTP deaminase family
N7E70_RS26280	COG2967	ApaG domain
N7E70_RS26290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7E70_RS26295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7E70_RS26305	COG0598	Magnesium transport protein CorA
N7E70_RS26310	COG0704	Plays a role in the regulation of phosphate uptake
N7E70_RS26320	COG0640	Transcriptional regulator
N7E70_RS26325	COG5002	protein histidine kinase activity
N7E70_RS26330	COG2326	polyphosphate kinase activity
N7E70_RS26335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS26345	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
N7E70_RS26375	COG1024	Enoyl-CoA hydratase
N7E70_RS26375	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_RS26380	COG0183	Belongs to the thiolase family
N7E70_RS26385	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS26390	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS26400	COG0730	response to heat
N7E70_RS26410	COG0789	Transcriptional regulator
N7E70_RS26420	COG1201	RNA secondary structure unwinding
N7E70_RS26440	COG1793	dna ligase
N7E70_RS26505	COG3422	double-strand break repair
N7E70_RS26520	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS26525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS26535	COG0747	negative chemotaxis
N7E70_RS26540	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS26545	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS26550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS26555	COG0601	transmembrane transport
N7E70_RS26560	COG0747	negative chemotaxis
N7E70_RS26575	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS26580	COG0546	phosphoglycolate phosphatase activity
N7E70_RS26585	COG0024	Methionine aminopeptidase
N7E70_RS26605	COG2226	methyltransferase
N7E70_RS26610	COG0129	dihydroxy-acid dehydratase activity
N7E70_RS26680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS26685	COG0166	Belongs to the GPI family
N7E70_RS26700	COG0489	protein tyrosine kinase activity
N7E70_RS26725	COG0583	DNA-binding transcription factor activity
N7E70_RS26740	COG3383	formate dehydrogenase (NAD+) activity
N7E70_RS26745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7E70_RS26755	COG2267	carboxylic ester hydrolase activity
N7E70_RS26790	COG5002	protein histidine kinase activity
N7E70_RS26795	COG1349	DNA-binding transcription factor activity
N7E70_RS26805	COG0517	IMP dehydrogenase activity
N7E70_RS26805	COG4175	Glycine betaine
N7E70_RS26810	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_RS26825	COG2340	Cysteine-rich secretory protein family
N7E70_RS26830	COG0697	spore germination
N7E70_RS26840	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS26845	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS26850	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS26855	COG3845	ABC transporter
N7E70_RS26865	COG1132	(ABC) transporter
N7E70_RS26870	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS26875	COG0288	reversible hydration of carbon dioxide
N7E70_RS26915	COG5002	protein histidine kinase activity
N7E70_RS26920	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N7E70_RS26925	COG0594	ribonuclease P activity
N7E70_RS26930	COG0706	membrane insertase activity
N7E70_RS26940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N7E70_RS26950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_RS26955	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N7E70_RS26970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N7E70_RS26985	COG3186	Phenylalanine-4-hydroxylase
N7E70_RS26995	COG0477	Major facilitator Superfamily
N7E70_RS27000	COG3706	GGDEF domain
N7E70_RS27020	COG2171	N-acyltransferase activity
N7E70_RS27030	COG3152	Membrane
N7E70_RS27050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS27070	COG0101	tRNA pseudouridine synthase activity
N7E70_RS27080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7E70_RS27085	COG0242	peptide deformylase activity
N7E70_RS27125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_RS27135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7E70_RS27140	COG3409	Peptidoglycan-binding domain 1 protein
N7E70_RS27140	COG3773	Cell wall hydrolase
N7E70_RS27150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N7E70_RS27155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7E70_RS27175	COG2816	NAD+ diphosphatase activity
N7E70_RS27180	COG2226	methyltransferase
N7E70_RS27185	COG0077	Prephenate dehydratase
N7E70_RS27185	COG1605	Chorismate mutase
N7E70_RS27190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N7E70_RS27195	COG3474	cytochrome
N7E70_RS27200	COG4166	transmembrane transport
N7E70_RS27205	COG4166	transmembrane transport
N7E70_RS27210	COG4174	ABC transporter (Permease)
N7E70_RS27215	COG4239	(ABC) transporter, permease
N7E70_RS27220	COG4172	Belongs to the ABC transporter superfamily
N7E70_RS27230	COG0791	NLP P60 protein
N7E70_RS27240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7E70_RS27275	COG4964	Belongs to the GSP D family
N7E70_RS27310	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N7E70_RS27315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N7E70_RS27320	COG1024	Enoyl-CoA hydratase
N7E70_RS27325	COG0268	Binds directly to 16S ribosomal RNA
N7E70_RS27330	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_RS27335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS27350	COG0028	Belongs to the TPP enzyme family
N7E70_RS27355	COG2855	membrane
N7E70_RS27375	COG0829	nickel cation binding
N7E70_RS27380	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_RS27385	COG0804	urea catabolic process
N7E70_RS27390	COG0832	Belongs to the urease beta subunit family
N7E70_RS27390	COG0831	urea catabolic process
N7E70_RS27395	COG0830	nickel cation binding
N7E70_RS27405	COG1126	abc transporter atp-binding protein
N7E70_RS27440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS27475	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS27485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS27490	COG0720	synthase
N7E70_RS27500	COG5001	Diguanylate cyclase
N7E70_RS27515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_RS27530	COG1921	L-seryl-tRNASec selenium transferase activity
N7E70_RS27545	COG3964	amidohydrolase
N7E70_RS27555	COG0601	transmembrane transport
N7E70_RS27560	COG0747	negative chemotaxis
N7E70_RS27575	COG1177	transmembrane transport
N7E70_RS27590	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_RS27595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_RS27605	COG0583	DNA-binding transcription factor activity
N7E70_RS27610	COG1129	ABC transporter
N7E70_RS27620	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS27635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_RS27640	COG1940	carbohydrate kinase activity
N7E70_RS27655	COG0517	IMP dehydrogenase activity
N7E70_RS27655	COG4175	Glycine betaine
N7E70_RS27660	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_RS27670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_RS27690	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS27695	COG0583	DNA-binding transcription factor activity
N7E70_RS27705	COG3806	Anti-sigma factor
N7E70_RS27710	COG1595	DNA-templated transcription, initiation
N7E70_RS27725	COG0300	oxidoreductase activity
N7E70_RS27755	COG2188	Transcriptional regulator
N7E70_RS27765	COG1940	carbohydrate kinase activity
N7E70_RS27765	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N7E70_RS27775	COG1175	transmembrane transport
N7E70_RS27780	COG0395	ABC-type sugar transport system, permease component
N7E70_RS27790	COG0235	Class ii aldolase
N7E70_RS27795	COG3254	rhamnose metabolic process
N7E70_RS27800	COG4952	isomerase
N7E70_RS27810	COG1070	Carbohydrate kinase
N7E70_RS27825	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS27830	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS27835	COG1129	ABC transporter
N7E70_RS27885	COG3002	Belongs to the UPF0753 family
N7E70_RS27915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_RS27925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_RS27925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N7E70_RS27935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_RS27940	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS27950	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_RS27955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_RS27960	COG0583	DNA-binding transcription factor activity
N7E70_RS27985	COG3415	Transposase
N7E70_RS27985	COG2801	Transposase and inactivated derivatives
N7E70_RS28025	COG0471	metal ion transport
N7E70_RS28025	COG0490	domain, Protein
N7E70_RS28040	COG2610	gluconate transmembrane transporter activity
N7E70_RS28085	COG0651	ATP synthesis coupled electron transport
N7E70_RS28090	COG0651	ATP synthesis coupled electron transport
N7E70_RS28130	COG2390	Transcriptional regulator
N7E70_RS28135	COG0500	methyltransferase
N7E70_RS28145	COG1414	Transcriptional regulator
N7E70_RS28150	COG1475	DNA binding
N7E70_RS28155	COG1192	Involved in chromosome partitioning
N7E70_RS28170	COG0277	FAD linked oxidase domain protein
N7E70_RS28180	COG0604	alcohol dehydrogenase
N7E70_RS28185	COG1024	Enoyl-CoA hydratase
N7E70_RS28205	COG3842	ATPase activity
N7E70_RS28210	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS28215	COG4208	sulfate ABC transporter
N7E70_RS28225	COG0765	amino acid transport
N7E70_RS28295	COG5001	Diguanylate cyclase
N7E70_RS28345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_RS28365	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N7E70_RS28370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N7E70_RS28375	COG3842	ATPase activity
N7E70_RS28400	COG2390	Transcriptional regulator
N7E70_RS28410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7E70_RS28420	COG3732	PTS system glucitol sorbitol-specific
N7E70_RS28440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_RS28450	COG1177	transmembrane transport
N7E70_RS28460	COG3842	ATPase activity
N7E70_RS28475	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS28480	COG0022	dehydrogenase e1 component
N7E70_RS28480	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_RS28485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7E70_RS28495	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_RS28500	COG1126	abc transporter atp-binding protein
N7E70_RS28505	COG0765	amino acid transport
N7E70_RS28510	COG0765	amino acid transport
N7E70_RS28515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS28530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_RS28600	COG1196	nuclear chromosome segregation
N7E70_RS28600	COG0741	lytic transglycosylase activity
N7E70_RS28600	COG0739	heme binding
N7E70_RS28610	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_RS28620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N7E70_RS28640	COG1013	pyruvate-flavodoxin oxidoreductase activity
N7E70_RS28700	COG1349	DNA-binding transcription factor activity
N7E70_RS28730	COG3795	YCII-related domain
N7E70_RS28745	COG0583	DNA-binding transcription factor activity
N7E70_RS28755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7E70_RS28765	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS28790	COG3842	ATPase activity
N7E70_RS28800	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS28820	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_RS28825	COG3842	ATPase activity
N7E70_RS28835	COG0625	glutathione transferase activity
N7E70_RS28845	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N7E70_RS28855	COG1522	sequence-specific DNA binding
N7E70_RS28880	COG0531	amino acid
N7E70_RS28935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7E70_RS28940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N7E70_RS28955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_RS28955	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_RS28965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS28975	COG0069	glutamate synthase activity
N7E70_RS28980	COG2218	PFAM glutamate synthase alpha subunit domain protein
N7E70_RS28985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_RS28995	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS29020	COG1215	transferase activity, transferring glycosyl groups
N7E70_RS29055	COG2379	hydroxypyruvate reductase
N7E70_RS29060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_RS29065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7E70_RS29070	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_RS29090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS29095	COG1957	nucleoside hydrolase
N7E70_RS29105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7E70_RS29150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7E70_RS29175	COG1271	oxidase subunit
N7E70_RS29180	COG1294	oxidase, subunit
N7E70_RS29195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS29200	COG2986	histidine ammonia-lyase
N7E70_RS29205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7E70_RS29215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7E70_RS29245	COG1120	ATPase activity
N7E70_RS29250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_RS29260	COG4206	TonB-dependent receptor
N7E70_RS29275	COG3483	tryptophan 2,3-dioxygenase activity
N7E70_RS29295	COG0411	ABC transporter
N7E70_RS29310	COG4120	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS29325	COG1802	Transcriptional regulator
N7E70_RS29330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_RS29345	COG1335	isochorismatase
N7E70_RS29360	COG1024	Enoyl-CoA hydratase
N7E70_RS29365	COG1960	acyl-CoA dehydrogenase activity
N7E70_RS29380	COG1024	Enoyl-CoA hydratase
N7E70_RS29380	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_RS29385	COG0183	Belongs to the thiolase family
N7E70_RS29390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS29400	COG0165	Argininosuccinate lyase
N7E70_RS29405	COG0395	ABC-type sugar transport system, permease component
N7E70_RS29410	COG1175	transmembrane transport
N7E70_RS29415	COG2182	Extracellular solute-binding protein
N7E70_RS29420	COG1940	carbohydrate kinase activity
N7E70_RS29435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_RS29435	COG3453	Protein conserved in bacteria
N7E70_RS29445	COG1522	sequence-specific DNA binding
N7E70_RS29450	COG0406	alpha-ribazole phosphatase activity
N7E70_RS29455	COG3842	ATPase activity
N7E70_RS29460	COG4149	molybdate abc transporter
N7E70_RS29485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_RS29490	COG1917	Cupin 2, conserved barrel domain protein
N7E70_RS29495	COG5285	phytanoyl-CoA dioxygenase
N7E70_RS29500	COG0527	aspartate kinase activity
N7E70_RS29505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS29510	COG0765	amino acid transport
N7E70_RS29515	COG0765	amino acid transport
N7E70_RS29520	COG1126	abc transporter atp-binding protein
N7E70_RS29530	COG4191	Histidine kinase
N7E70_RS29535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N7E70_RS29540	COG1802	Transcriptional regulator
N7E70_RS29545	COG3938	Belongs to the proline racemase family
N7E70_RS29550	COG1476	TRANSCRIPTIONal
N7E70_RS29555	COG0747	negative chemotaxis
N7E70_RS29560	COG0601	transmembrane transport
N7E70_RS29565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS29570	COG0444	Belongs to the ABC transporter superfamily
N7E70_RS29575	COG4608	Belongs to the ABC transporter superfamily
N7E70_RS29580	COG0006	proline dipeptidase activity
N7E70_RS29600	COG1846	Transcriptional regulator
N7E70_RS29620	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_RS29625	COG3971	2-oxopent-4-enoate hydratase activity
N7E70_RS29635	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS29645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_RS29650	COG0601	transmembrane transport
N7E70_RS29660	COG2186	Transcriptional regulator
N7E70_RS29690	COG2159	amidohydrolase
N7E70_RS29695	COG3384	dioxygenase
N7E70_RS29705	COG0473	3-isopropylmalate dehydrogenase activity
N7E70_RS29705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_RS29710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_RS29720	COG1448	Aminotransferase
N7E70_RS29725	COG0028	Belongs to the TPP enzyme family
N7E70_RS29760	COG1022	Amp-dependent synthetase and ligase
N7E70_RS29770	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_RS29810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_RS29815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_RS29825	COG0523	cobalamin synthesis protein
N7E70_RS29840	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_RS29855	COG1942	4-Oxalocrotonate Tautomerase
N7E70_RS29870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N7E70_RS29885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_RS29905	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_RS29915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_RS29920	COG4521	taurine ABC transporter
N7E70_RS29930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7E70_RS29950	COG5489	Protein of unknown function (DUF736)
N7E70_RS29955	COG4227	nucleotidyltransferase activity
N7E70_RS29960	COG3831	ATPase activity
N7E70_RS29985	COG1475	DNA binding
N7E70_RS30045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7E70_RS30050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_RS30060	COG1454	alcohol dehydrogenase
N7E70_RS30070	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS30075	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_RS30080	COG0625	glutathione transferase activity
N7E70_RS30085	COG0277	FAD linked oxidase domain protein
N7E70_RS30105	COG0395	ABC-type sugar transport system, permease component
N7E70_RS30110	COG1175	transmembrane transport
N7E70_RS30115	COG1653	transport
N7E70_RS30120	COG3842	ATPase activity
N7E70_RS30125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_RS30135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_RS30175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_RS30205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_RS30220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7E70_RS30230	COG0640	Transcriptional regulator
N7E70_RS30235	COG1475	DNA binding
N7E70_RS30240	COG1192	Involved in chromosome partitioning
N7E70_RS30250	COG3177	Filamentation induced by cAMP protein fic
N7E70_RS30260	COG3916	Acyl-homoserine-lactone synthase
N7E70_RS30265	COG4962	Type ii secretion system protein e
N7E70_RS30270	COG3838	Conjugal transfer protein Trbc
N7E70_RS30275	COG5268	conjugation
N7E70_RS30280	COG3451	type IV secretory pathway VirB4
N7E70_RS30285	COG5314	conjugation
N7E70_RS30295	COG3846	protein secretion by the type IV secretion system
N7E70_RS30300	COG3701	Conjugal transfer protein
N7E70_RS30370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7E70_RS30390	COG4959	Type IV secretory pathway protease TraF
N7E70_RS30395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_RS30465	COG3701	Conjugal transfer protein
N7E70_RS30470	COG3846	protein secretion by the type IV secretion system
N7E70_RS30480	COG5314	conjugation
N7E70_RS30485	COG3451	type IV secretory pathway VirB4
N7E70_RS30495	COG3838	Conjugal transfer protein Trbc
N7E70_RS30500	COG4962	Type ii secretion system protein e
N7E70_RS30505	COG1192	Involved in chromosome partitioning
N7E70_RS30510	COG1475	DNA binding
N7E70_RS30515	COG0640	Transcriptional regulator
N7E70_RS30520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7E70_RS30535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_RS30560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_RS30575	COG0174	glutamine synthetase
N7E70_RS30580	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_RS30590	COG1414	Transcriptional regulator
N7E70_RS30595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7E70_RS30600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_RS30605	COG3616	Alanine racemase, N-terminal domain
N7E70_RS30610	COG2423	ornithine cyclodeaminase activity
N7E70_RS30620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_RS30630	COG3842	ATPase activity
N7E70_RS30635	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_RS30650	COG2801	Transposase and inactivated derivatives
N7E70_RS30665	COG0028	Belongs to the TPP enzyme family
N7E70_RS30675	COG1271	oxidase subunit
N7E70_RS30680	COG1294	oxidase, subunit
N7E70_RS30695	COG4566	intracellular signal transduction
N7E70_RS30700	COG2198	Histidine kinase
N7E70_RS30700	COG2205	protein histidine kinase activity
N7E70_RS30700	COG0784	Response regulator, receiver
N7E70_RS30700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_RS30740	COG1475	DNA binding
N7E70_RS30760	COG2824	Alkylphosphonate utilization operon protein PhnA
N7E70_RS30775	COG4227	nucleotidyltransferase activity
N7E70_RS30785	COG5489	Protein of unknown function (DUF736)
N7E70_RS30790	COG3831	ATPase activity
N7E70_RS30795	COG3505	Type IV secretory pathway VirD4