locus-tag	class	description
ADEG_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADEG_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADEG_RS00025	COG0187	DNA topoisomerase II activity
ADEG_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADEG_RS00035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ADEG_RS00040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADEG_RS00045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ADEG_RS00050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADEG_RS00055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADEG_RS00070	COG0582	viral genome integration into host DNA
ADEG_RS00120	COG0517	IMP dehydrogenase activity
ADEG_RS00150	COG0247	lactate metabolic process
ADEG_RS00155	COG2920	part of a sulfur-relay system
ADEG_RS00160	COG1797	cobyrinic acid a,c-diamide synthase activity
ADEG_RS00165	COG1324	tolerance protein
ADEG_RS00170	COG1515	deoxyribonuclease V activity
ADEG_RS00210	COG3464	Transposase
ADEG_RS00215	COG1522	sequence-specific DNA binding
ADEG_RS00220	COG0436	Aminotransferase
ADEG_RS00230	COG0018	arginyl-trna synthetase
ADEG_RS00235	COG0504	CTP synthase activity
ADEG_RS00240	COG0616	signal peptide processing
ADEG_RS00250	COG2204	response regulator
ADEG_RS00265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADEG_RS00270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADEG_RS00285	COG0254	rRNA binding
ADEG_RS00290	COG3872	metal-dependent enzyme
ADEG_RS00295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADEG_RS00300	COG2890	protein-(glutamine-N5) methyltransferase activity
ADEG_RS00305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADEG_RS00315	COG0009	L-threonylcarbamoyladenylate synthase
ADEG_RS00320	COG1971	Probably functions as a manganese efflux pump
ADEG_RS00330	COG0698	ribose 5-phosphate isomerase
ADEG_RS00335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADEG_RS00350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ADEG_RS00365	COG0356	it plays a direct role in the translocation of protons across the membrane
ADEG_RS00370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADEG_RS00375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADEG_RS00380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADEG_RS00385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADEG_RS00390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADEG_RS00395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADEG_RS00400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADEG_RS00405	COG2385	sporulation resulting in formation of a cellular spore
ADEG_RS00410	COG1609	Transcriptional regulator
ADEG_RS00415	COG3693	PFAM glycoside hydrolase, family 10
ADEG_RS00460	COG0109	protoheme IX farnesyltransferase activity
ADEG_RS00470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADEG_RS00480	COG2814	Major facilitator Superfamily
ADEG_RS00500	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS00505	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS00530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADEG_RS00540	COG1301	dicarboxylic acid transport
ADEG_RS00550	COG3314	Sporulation integral membrane protein YlbJ
ADEG_RS00560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADEG_RS00565	COG0742	ribosomal rna small subunit methyltransferase
ADEG_RS00570	COG1396	sequence-specific DNA binding
ADEG_RS00575	COG1476	TRANSCRIPTIONal
ADEG_RS00610	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADEG_RS00620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADEG_RS00625	COG1111	helicase
ADEG_RS00625	COG1205	dead DEAH box helicase
ADEG_RS00635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADEG_RS00660	COG1702	phosphate starvation-inducible protein PhoH
ADEG_RS00665	COG1480	7TM receptor with intracellular HD hydrolase
ADEG_RS00670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADEG_RS00675	COG0295	cytidine deaminase activity
ADEG_RS00680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADEG_RS00700	COG0537	adenosine 5'-monophosphoramidase activity
ADEG_RS00705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADEG_RS00710	COG0352	thiamine-phosphate diphosphorylase activity
ADEG_RS00715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADEG_RS00720	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADEG_RS00725	COG0802	atpase or kinase
ADEG_RS00730	COG1214	PFAM Peptidase M22, glycoprotease
ADEG_RS00735	COG0456	acetyltransferase
ADEG_RS00740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADEG_RS00750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ADEG_RS00775	COG3383	formate dehydrogenase (NAD+) activity
ADEG_RS00790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADEG_RS00800	COG0459	protein refolding
ADEG_RS00810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADEG_RS00825	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADEG_RS00840	COG0281	malic enzyme
ADEG_RS00845	COG0037	tRNA processing
ADEG_RS00850	COG2855	membrane
ADEG_RS00855	COG3852	Histidine kinase
ADEG_RS00860	COG2204	response regulator
ADEG_RS00865	COG0589	response to stress
ADEG_RS00880	COG1067	ATP-dependent peptidase activity
ADEG_RS00885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADEG_RS00890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADEG_RS00895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADEG_RS00900	COG1492	cobalamin metabolic process
ADEG_RS00905	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ADEG_RS00910	COG1797	cobyrinic acid a,c-diamide synthase activity
ADEG_RS00920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADEG_RS00925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADEG_RS00935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADEG_RS00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS00950	COG0724	RNA recognition motif
ADEG_RS00955	COG0799	negative regulation of ribosome biogenesis
ADEG_RS00960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADEG_RS00995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADEG_RS01000	COG1686	Belongs to the peptidase S11 family
ADEG_RS01030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ADEG_RS01040	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADEG_RS01045	COG0010	Belongs to the arginase family
ADEG_RS01050	COG0482	sulfurtransferase activity
ADEG_RS01060	COG0557	exoribonuclease II activity
ADEG_RS01065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADEG_RS01070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADEG_RS01075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS01100	COG2078	PFAM AMMECR1 domain protein
ADEG_RS01100	COG3885	ferrous iron binding
ADEG_RS01125	COG0129	dihydroxy-acid dehydratase activity
ADEG_RS01130	COG0028	Belongs to the TPP enzyme family
ADEG_RS01140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADEG_RS01145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADEG_RS01150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADEG_RS01155	COG0066	3-isopropylmalate dehydratase activity
ADEG_RS01160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADEG_RS01165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADEG_RS01170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADEG_RS01175	COG3546	catalase activity
ADEG_RS01190	COG3464	Transposase
ADEG_RS01195	COG3464	Transposase
ADEG_RS01215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ADEG_RS01220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ADEG_RS01235	COG0835	chemotaxis
ADEG_RS01240	COG0643	Histidine kinase
ADEG_RS01240	COG2198	Histidine kinase
ADEG_RS01275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADEG_RS01280	COG0463	Glycosyl transferase, family 2
ADEG_RS01280	COG0457	Tetratricopeptide repeat
ADEG_RS01290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ADEG_RS01390	COG3464	Transposase
ADEG_RS01400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEG_RS01410	COG2442	InterPro IPR007367
ADEG_RS01415	COG1120	ATPase activity
ADEG_RS01420	COG3383	formate dehydrogenase (NAD+) activity
ADEG_RS01420	COG0243	molybdopterin cofactor binding
ADEG_RS01430	COG0437	4 iron, 4 sulfur cluster binding
ADEG_RS01430	COG3064	Membrane
ADEG_RS01445	COG1028	Short-chain dehydrogenase reductase Sdr
ADEG_RS01470	COG3064	Membrane
ADEG_RS01470	COG0437	4 iron, 4 sulfur cluster binding
ADEG_RS01475	COG5557	Pfam Polysulphide reductase, NrfD
ADEG_RS01480	COG3344	reverse transcriptase
ADEG_RS01485	COG0525	valine-tRNA ligase activity
ADEG_RS01490	COG0285	dihydrofolate synthase activity
ADEG_RS01500	COG0697	spore germination
ADEG_RS01515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADEG_RS01520	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADEG_RS01545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADEG_RS01550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADEG_RS01560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADEG_RS01565	COG0138	bifunctional purine biosynthesis protein purh
ADEG_RS01570	COG0151	Belongs to the GarS family
ADEG_RS01580	COG0131	Imidazoleglycerol-phosphate dehydratase
ADEG_RS01585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADEG_RS01590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADEG_RS01595	COG0107	imidazoleglycerol-phosphate synthase activity
ADEG_RS01620	COG1032	radical SAM domain protein
ADEG_RS01675	COG1151	hydroxylamine reductase activity
ADEG_RS01710	COG3573	Dehydrogenase
ADEG_RS01725	COG0646	methionine synthase
ADEG_RS01725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ADEG_RS01735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADEG_RS01740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADEG_RS01745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADEG_RS01750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADEG_RS01755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADEG_RS01765	COG1116	anion transmembrane transporter activity
ADEG_RS01780	COG0426	domain, Protein
ADEG_RS01810	COG2252	PERMEase
ADEG_RS01815	COG3464	Transposase
ADEG_RS01840	COG2814	Major facilitator Superfamily
ADEG_RS01850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADEG_RS01855	COG0540	Belongs to the ATCase OTCase family
ADEG_RS01860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADEG_RS01865	COG0505	Belongs to the CarA family
ADEG_RS01870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADEG_RS01875	COG0543	2 iron, 2 sulfur cluster binding
ADEG_RS01880	COG0167	dihydroorotate dehydrogenase activity
ADEG_RS01885	COG0284	orotidine-5'-phosphate decarboxylase activity
ADEG_RS01890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADEG_RS01900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADEG_RS01905	COG1490	D-aminoacyl-tRNA deacylase activity
ADEG_RS01910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADEG_RS01935	COG0174	glutamine synthetase
ADEG_RS01940	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ADEG_RS01945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADEG_RS01970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADEG_RS01975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADEG_RS01980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADEG_RS01985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADEG_RS01990	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ADEG_RS02005	COG1329	Transcriptional regulator
ADEG_RS02010	COG4956	integral membrane protein (PIN domain superfamily)
ADEG_RS02015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADEG_RS02015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADEG_RS02020	COG1045	serine acetyltransferase
ADEG_RS02025	COG0215	cysteine-tRNA ligase activity
ADEG_RS02030	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ADEG_RS02035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADEG_RS02040	COG3688	RNA-binding protein containing a PIN domain
ADEG_RS02075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADEG_RS02120	COG0582	viral genome integration into host DNA
ADEG_RS02130	COG3464	Transposase
ADEG_RS02135	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ADEG_RS02140	COG0822	iron-sulfur transferase activity
ADEG_RS02145	COG1104	cysteine desulfurase activity
ADEG_RS02155	COG1959	2 iron, 2 sulfur cluster binding
ADEG_RS02170	COG1543	Belongs to the glycosyl hydrolase 57 family
ADEG_RS02190	COG0791	NLP P60 protein
ADEG_RS02210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADEG_RS02215	COG0825	malonyl-CoA metabolic process
ADEG_RS02220	COG0205	6-phosphofructokinase activity
ADEG_RS02250	COG0071	Belongs to the small heat shock protein (HSP20) family
ADEG_RS02260	COG0494	nUDIX hydrolase
ADEG_RS02270	COG0850	regulation of cytokinetic process
ADEG_RS02280	COG0297	glycogen (starch) synthase activity
ADEG_RS02290	COG2719	SpoVR family
ADEG_RS02295	COG0581	inorganic phosphate transmembrane transporter activity
ADEG_RS02300	COG0573	inorganic phosphate transmembrane transporter activity
ADEG_RS02305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADEG_RS02315	COG2199	diguanylate cyclase activity
ADEG_RS02315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADEG_RS02325	COG3679	Belongs to the UPF0342 family
ADEG_RS02330	COG2199	diguanylate cyclase activity
ADEG_RS02345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADEG_RS02355	COG0653	protein targeting
ADEG_RS02360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADEG_RS02365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ADEG_RS02370	COG3959	Transketolase, thiamine diphosphate binding domain
ADEG_RS02375	COG3958	Transketolase
ADEG_RS02380	COG2884	Cell division ATP-binding protein ftsE
ADEG_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
ADEG_RS02390	COG4942	peptidase
ADEG_RS02395	COG0793	Belongs to the peptidase S41A family
ADEG_RS02395	COG3409	Peptidoglycan-binding domain 1 protein
ADEG_RS02405	COG1376	ErfK ybiS ycfS ynhG family protein
ADEG_RS02410	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS02420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADEG_RS02430	COG3464	Transposase
ADEG_RS02475	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADEG_RS02480	COG0740	serine-type endopeptidase activity
ADEG_RS02485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADEG_RS02490	COG0675	Transposase, IS605 OrfB family
ADEG_RS02495	COG0470	DNA polymerase III
ADEG_RS02495	COG1067	ATP-dependent peptidase activity
ADEG_RS02500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADEG_RS02515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADEG_RS02555	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS02565	COG1487	ribonuclease activity
ADEG_RS02595	COG3464	Transposase
ADEG_RS02630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADEG_RS02670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADEG_RS02695	COG3852	Histidine kinase
ADEG_RS02710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADEG_RS02715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADEG_RS02720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADEG_RS02735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADEG_RS02740	COG0072	phenylalanine-tRNA ligase activity
ADEG_RS02740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADEG_RS02745	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ADEG_RS02755	COG0826	peptidase U32
ADEG_RS02760	COG1193	negative regulation of DNA recombination
ADEG_RS02770	COG0396	ATPase activity
ADEG_RS02775	COG1372	Participates in initiation and elongation during chromosome replication
ADEG_RS02775	COG0719	Fe-S assembly protein
ADEG_RS02780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADEG_RS02780	COG2111	Na H antiporter
ADEG_RS02785	COG0650	Formate hydrogenlyase subunit 4
ADEG_RS02790	COG3260	NADH ubiquinone oxidoreductase 20
ADEG_RS02795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADEG_RS02800	COG0649	NAD binding
ADEG_RS02815	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ADEG_RS02820	COG1131	(ABC) transporter
ADEG_RS02825	COG0842	Transport permease protein
ADEG_RS02850	COG0277	FAD linked oxidase domain protein
ADEG_RS02855	COG2186	Transcriptional regulator
ADEG_RS02860	COG1620	l-lactate permease
ADEG_RS02870	COG1139	Iron-sulfur cluster binding protein
ADEG_RS02875	COG0012	GTP binding
ADEG_RS02885	COG0861	Integral membrane protein TerC family
ADEG_RS02890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADEG_RS02895	COG0758	DNA mediated transformation
ADEG_RS02895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADEG_RS02900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADEG_RS02905	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ADEG_RS02910	COG4974	Belongs to the 'phage' integrase family
ADEG_RS02920	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADEG_RS02925	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADEG_RS02930	COG0052	Belongs to the universal ribosomal protein uS2 family
ADEG_RS02935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADEG_RS02940	COG0528	UMP kinase activity
ADEG_RS02945	COG0233	cytoplasmic translational termination
ADEG_RS02960	COG4589	Belongs to the CDS family
ADEG_RS02965	COG0628	permease
ADEG_RS02970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADEG_RS02975	COG0750	zinc metalloprotease
ADEG_RS02980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADEG_RS02985	COG0442	prolyl-tRNA aminoacylation
ADEG_RS02995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADEG_RS03005	COG0602	queuosine metabolic process
ADEG_RS03010	COG0302	gtp cyclohydrolase
ADEG_RS03020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADEG_RS03030	COG2244	polysaccharide biosynthetic process
ADEG_RS03045	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS03050	COG0481	GTPase activity
ADEG_RS03055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADEG_RS03060	COG1420	regulation of RNA biosynthetic process
ADEG_RS03075	COG0443	Heat shock 70 kDa protein
ADEG_RS03080	COG0484	heat shock protein binding
ADEG_RS03085	COG2264	protein methyltransferase activity
ADEG_RS03090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADEG_RS03095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADEG_RS03100	COG2359	stage V sporulation protein S
ADEG_RS03110	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
ADEG_RS03120	COG0726	polysaccharide deacetylase
ADEG_RS03140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADEG_RS03145	COG0047	phosphoribosylformylglycinamidine synthase activity
ADEG_RS03150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADEG_RS03165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADEG_RS03170	COG1058	Belongs to the CinA family
ADEG_RS03170	COG1546	Belongs to the CinA family
ADEG_RS03180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADEG_RS03195	COG0589	response to stress
ADEG_RS03205	COG1918	ferrous iron import across plasma membrane
ADEG_RS03205	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADEG_RS03215	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADEG_RS03215	COG1918	ferrous iron import across plasma membrane
ADEG_RS03235	COG0725	ABC transporter, periplasmic molybdate-binding protein
ADEG_RS03245	COG3842	ATPase activity
ADEG_RS03265	COG3464	Transposase
ADEG_RS03270	COG0745	RESPONSE REGULATOR receiver
ADEG_RS03285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ADEG_RS03295	COG1877	trehalose-phosphatase activity
ADEG_RS03300	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ADEG_RS03350	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ADEG_RS03355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADEG_RS03360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADEG_RS03365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADEG_RS03370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADEG_RS03375	COG0312	modulator of DNA gyrase
ADEG_RS03380	COG0312	modulator of DNA gyrase
ADEG_RS03385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADEG_RS03390	COG0006	proline dipeptidase activity
ADEG_RS03395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADEG_RS03400	COG1980	fructose-bisphosphate aldolase activity
ADEG_RS03405	COG0671	phosphoesterase, PA-phosphatase related
ADEG_RS03415	COG1518	maintenance of DNA repeat elements
ADEG_RS03420	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADEG_RS03425	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADEG_RS03430	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADEG_RS03435	COG1921	L-seryl-tRNASec selenium transferase activity
ADEG_RS03475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADEG_RS03510	COG0629	single-stranded DNA binding
ADEG_RS03635	COG4974	Belongs to the 'phage' integrase family
ADEG_RS03820	COG2199	diguanylate cyclase activity
ADEG_RS03820	COG2200	EAL domain
ADEG_RS03820	COG3287	FIST C domain
ADEG_RS03885	COG1215	transferase activity, transferring glycosyl groups
ADEG_RS03950	COG0489	protein tyrosine kinase activity
ADEG_RS04055	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADEG_RS04055	COG2199	diguanylate cyclase activity
ADEG_RS04230	COG0582	viral genome integration into host DNA
ADEG_RS04270	COG2052	Domain of unknown function (DUF370)
ADEG_RS04275	COG0194	GDP metabolic process
ADEG_RS04300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADEG_RS04310	COG1215	transferase activity, transferring glycosyl groups
ADEG_RS04350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADEG_RS04355	COG0242	peptide deformylase activity
ADEG_RS04360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADEG_RS04365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADEG_RS04365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADEG_RS04370	COG1686	Belongs to the peptidase S11 family
ADEG_RS04375	COG1366	Belongs to the anti-sigma-factor antagonist family
ADEG_RS04380	COG2172	sigma factor antagonist activity
ADEG_RS04385	COG1191	sigma factor activity
ADEG_RS04405	COG0726	polysaccharide deacetylase
ADEG_RS04410	COG1686	Belongs to the peptidase S11 family
ADEG_RS04480	COG0582	viral genome integration into host DNA
ADEG_RS04485	COG0460	homoserine dehydrogenase
ADEG_RS04490	COG0083	homoserine kinase activity
ADEG_RS04505	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADEG_RS04510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADEG_RS04510	COG0519	Catalyzes the synthesis of GMP from XMP
ADEG_RS04525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADEG_RS04540	COG1328	CTP reductase activity
ADEG_RS04540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADEG_RS04560	COG1966	Carbon starvation protein
ADEG_RS04570	COG3275	phosphorelay sensor kinase activity
ADEG_RS04585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADEG_RS04590	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADEG_RS04595	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS04610	COG1233	COG1233 Phytoene dehydrogenase and related
ADEG_RS04615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADEG_RS04645	COG1337	RAMP superfamily
ADEG_RS04665	COG0303	'Molybdopterin
ADEG_RS04670	COG1910	domain protein
ADEG_RS04675	COG0315	cyclic pyranopterin monophosphate synthase activity
ADEG_RS04680	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADEG_RS04685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADEG_RS04690	COG1053	succinate dehydrogenase
ADEG_RS04700	COG0010	Belongs to the arginase family
ADEG_RS04705	COG0310	cobalt ion transport
ADEG_RS04720	COG1122	ATPase activity
ADEG_RS04725	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ADEG_RS04770	COG1618	nucleotide phosphatase activity, acting on free nucleotides
ADEG_RS04775	COG1030	water channel activity
ADEG_RS04780	COG0330	HflC and HflK could
ADEG_RS04790	COG1773	rubredoxin
ADEG_RS04795	COG2033	superoxide reductase activity
ADEG_RS04825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADEG_RS04840	COG0416	fatty acid biosynthetic process
ADEG_RS04845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADEG_RS04850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADEG_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
ADEG_RS04860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADEG_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADEG_RS04870	COG0571	ribonuclease III activity
ADEG_RS04875	COG0552	protein localization to endoplasmic reticulum
ADEG_RS04880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADEG_RS04885	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADEG_RS04890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADEG_RS04900	COG0402	S-adenosylhomocysteine deaminase activity
ADEG_RS04905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADEG_RS05025	COG1268	BioY protein
ADEG_RS05040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADEG_RS05045	COG1309	transcriptional regulator
ADEG_RS05050	COG2210	Belongs to the sulfur carrier protein TusA family
ADEG_RS05065	COG0145	ligase activity
ADEG_RS05075	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADEG_RS05110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADEG_RS05125	COG0745	RESPONSE REGULATOR receiver
ADEG_RS05130	COG5002	protein histidine kinase activity
ADEG_RS05135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADEG_RS05145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADEG_RS05150	COG1799	cell septum assembly
ADEG_RS05155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADEG_RS05160	COG0762	integral membrane protein
ADEG_RS05165	COG1872	DUF167
ADEG_RS05170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADEG_RS05175	COG0741	lytic transglycosylase activity
ADEG_RS05180	COG0237	dephospho-CoA kinase activity
ADEG_RS05185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADEG_RS05215	COG5002	protein histidine kinase activity
ADEG_RS05220	COG0745	RESPONSE REGULATOR receiver
ADEG_RS05230	COG0586	Pfam SNARE associated Golgi protein
ADEG_RS05240	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS05280	COG2197	response regulator
ADEG_RS05320	COG1191	sigma factor activity
ADEG_RS05420	COG3344	reverse transcriptase
ADEG_RS05425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADEG_RS05435	COG2766	serine protein kinase
ADEG_RS05440	COG2718	Belongs to the UPF0229 family
ADEG_RS05480	COG0501	Belongs to the peptidase M48B family
ADEG_RS05515	COG0489	protein tyrosine kinase activity
ADEG_RS05520	COG2894	cell division
ADEG_RS05540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADEG_RS05545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADEG_RS05550	COG0154	amidase activity
ADEG_RS05555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADEG_RS05565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADEG_RS05570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADEG_RS05575	COG0066	3-isopropylmalate dehydratase activity
ADEG_RS05580	COG0473	3-isopropylmalate dehydrogenase activity
ADEG_RS05585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADEG_RS05590	COG1116	anion transmembrane transporter activity
ADEG_RS05600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADEG_RS05605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADEG_RS05610	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADEG_RS05615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ADEG_RS05670	COG1695	Transcriptional regulator
ADEG_RS05675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADEG_RS05690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADEG_RS05700	COG0457	Tetratricopeptide repeat
ADEG_RS05700	COG0463	Glycosyl transferase, family 2
ADEG_RS05715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADEG_RS05720	COG3464	Transposase
ADEG_RS05740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADEG_RS05745	COG0516	GMP reductase activity
ADEG_RS05745	COG0517	IMP dehydrogenase activity
ADEG_RS05755	COG1918	ferrous iron import across plasma membrane
ADEG_RS05755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADEG_RS05790	COG0539	negative regulation of cytoplasmic translation
ADEG_RS05790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADEG_RS05795	COG0204	Acyl-transferase
ADEG_RS05800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADEG_RS05805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADEG_RS05810	COG0287	Prephenate dehydrogenase
ADEG_RS05820	COG0077	Prephenate dehydratase
ADEG_RS05825	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADEG_RS05830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADEG_RS05835	COG0159	tryptophan synthase activity
ADEG_RS05840	COG0133	tryptophan synthase activity
ADEG_RS05845	COG0135	phosphoribosylanthranilate isomerase activity
ADEG_RS05850	COG0134	indole-3-glycerol-phosphate synthase activity
ADEG_RS05855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADEG_RS05860	COG0512	Glutamine amidotransferase of anthranilate synthase
ADEG_RS05870	COG3464	Transposase
ADEG_RS05875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADEG_RS05900	COG0482	sulfurtransferase activity
ADEG_RS05905	COG1683	Conserved Protein
ADEG_RS06000	COG2855	membrane
ADEG_RS06025	COG0531	amino acid
ADEG_RS06035	COG1120	ATPase activity
ADEG_RS06040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEG_RS06065	COG5557	Pfam Polysulphide reductase, NrfD
ADEG_RS06070	COG3064	Membrane
ADEG_RS06070	COG0437	4 iron, 4 sulfur cluster binding
ADEG_RS06095	COG1573	uracil-dna glycosylase
ADEG_RS06100	COG1122	ATPase activity
ADEG_RS06110	COG0475	glutathione-regulated potassium exporter activity
ADEG_RS06120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADEG_RS06130	COG0432	Pfam Uncharacterised protein family UPF0047
ADEG_RS06140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADEG_RS06145	COG1121	(ABC) transporter
ADEG_RS06150	COG0803	Belongs to the bacterial solute-binding protein 9 family
ADEG_RS06155	COG0735	belongs to the Fur family
ADEG_RS06165	COG0084	hydrolase, TatD family'
ADEG_RS06175	COG2146	nitrite reductase [NAD(P)H] activity
ADEG_RS06175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADEG_RS06180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADEG_RS06185	COG1160	GTP binding
ADEG_RS06190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADEG_RS06205	COG0840	transmembrane signaling receptor activity
ADEG_RS06205	COG3290	protein histidine kinase activity
ADEG_RS06210	COG0805	protein transport
ADEG_RS06215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADEG_RS06230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADEG_RS06235	COG0205	6-phosphofructokinase activity
ADEG_RS06250	COG0563	adenylate kinase activity
ADEG_RS06270	COG1027	Aspartate ammonia-lyase
ADEG_RS06285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADEG_RS06290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADEG_RS06295	COG0697	spore germination
ADEG_RS06305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADEG_RS06325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADEG_RS06330	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADEG_RS06335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADEG_RS06340	COG1522	sequence-specific DNA binding
ADEG_RS06345	COG1522	sequence-specific DNA binding
ADEG_RS06350	COG0535	radical SAM domain protein
ADEG_RS06355	COG0113	porphobilinogen synthase activity
ADEG_RS06365	COG0181	hydroxymethylbilane synthase activity
ADEG_RS06370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADEG_RS06375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADEG_RS06375	COG1648	precorrin-2 dehydrogenase activity
ADEG_RS06400	COG0740	serine-type endopeptidase activity
ADEG_RS06405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADEG_RS06405	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ADEG_RS06415	COG2848	UPF0210 protein
ADEG_RS06420	COG3830	Belongs to the UPF0237 family
ADEG_RS06425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADEG_RS06430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADEG_RS06440	COG1862	Preprotein translocase
ADEG_RS06445	COG0343	queuine tRNA-ribosyltransferase activity
ADEG_RS06450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADEG_RS06460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADEG_RS06470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADEG_RS06485	COG1302	Protein conserved in bacteria
ADEG_RS06490	COG0439	Biotin carboxylase
ADEG_RS06495	COG5016	pyruvate
ADEG_RS06495	COG0511	ligase activity, forming carbon-carbon bonds
ADEG_RS06510	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS06515	COG5002	protein histidine kinase activity
ADEG_RS06515	COG5001	Diguanylate cyclase
ADEG_RS06530	COG1187	pseudouridine synthase activity
ADEG_RS06535	COG0700	Nucleoside recognition
ADEG_RS06540	COG0741	lytic transglycosylase activity
ADEG_RS06550	COG2715	membrane protein required for spore maturation
ADEG_RS06555	COG3874	Sporulation protein YtfJ
ADEG_RS06570	COG0180	Tryptophanyl-tRNA synthetase
ADEG_RS06575	COG1994	Peptidase M50
ADEG_RS06580	COG3620	sequence-specific DNA binding
ADEG_RS06580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ADEG_RS06580	COG0617	tRNA 3'-terminal CCA addition
ADEG_RS06585	COG0019	diaminopimelate decarboxylase activity
ADEG_RS06610	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ADEG_RS06615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADEG_RS06620	COG1162	GTPase activity
ADEG_RS06625	COG0515	serine threonine protein kinase
ADEG_RS06625	COG2815	serine threonine protein kinase
ADEG_RS06630	COG0631	protein serine/threonine phosphatase activity
ADEG_RS06635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADEG_RS06665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ADEG_RS06690	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ADEG_RS06700	COG1694	Mazg nucleotide pyrophosphohydrolase
ADEG_RS06715	COG2871	sodium ion transport
ADEG_RS06735	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ADEG_RS06740	COG2048	Heterodisulfide reductase, subunit B
ADEG_RS06750	COG0582	viral genome integration into host DNA
ADEG_RS06795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADEG_RS06800	COG1201	RNA secondary structure unwinding
ADEG_RS06920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADEG_RS06965	COG0450	alkyl hydroperoxide reductase
ADEG_RS06975	COG0436	Aminotransferase
ADEG_RS06980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADEG_RS07015	COG0463	Glycosyl transferase, family 2
ADEG_RS07030	COG0745	RESPONSE REGULATOR receiver
ADEG_RS07035	COG0750	zinc metalloprotease
ADEG_RS07040	COG0497	DNA recombination
ADEG_RS07045	COG1438	arginine binding
ADEG_RS07050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADEG_RS07055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ADEG_RS07060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADEG_RS07075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ADEG_RS07080	COG1342	Belongs to the UPF0251 family
ADEG_RS07085	COG0606	chelatase, subunit chli
ADEG_RS07090	COG0675	Transposase, IS605 OrfB family
ADEG_RS07100	COG0792	nuclease activity
ADEG_RS07105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADEG_RS07110	COG1509	lysine 2,3-aminomutase activity
ADEG_RS07115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ADEG_RS07120	COG0681	Belongs to the peptidase S26 family
ADEG_RS07125	COG0335	large ribosomal subunit rRNA binding
ADEG_RS07130	COG0336	Belongs to the RNA methyltransferase TrmD family
ADEG_RS07135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADEG_RS07150	COG0228	four-way junction DNA binding
ADEG_RS07155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADEG_RS07160	COG1110	DNA topoisomerase II activity
ADEG_RS07195	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADEG_RS07215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADEG_RS07215	COG2146	nitrite reductase [NAD(P)H] activity
ADEG_RS07230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADEG_RS07245	COG0768	penicillin binding
ADEG_RS07250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADEG_RS07255	COG2720	vancomycin resistance protein
ADEG_RS07260	COG3906	Belongs to the UPF0473 family
ADEG_RS07265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADEG_RS07270	COG4472	Bacterial protein of unknown function (DUF965)
ADEG_RS07275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADEG_RS07290	COG0653	protein targeting
ADEG_RS07300	COG0038	chloride channel
ADEG_RS07315	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADEG_RS07320	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ADEG_RS07325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADEG_RS07330	COG2226	methyltransferase
ADEG_RS07340	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ADEG_RS07350	COG3464	Transposase
ADEG_RS07360	COG0589	response to stress
ADEG_RS07400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ADEG_RS07430	COG2359	stage V sporulation protein S
ADEG_RS07435	COG1692	metallophosphoesterase
ADEG_RS07440	COG1418	mRNA catabolic process
ADEG_RS07450	COG0438	transferase activity, transferring glycosyl groups
ADEG_RS07470	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ADEG_RS07475	COG2205	protein histidine kinase activity
ADEG_RS07480	COG0658	competence protein
ADEG_RS07480	COG2333	competence protein COMEC
ADEG_RS07490	COG2323	membrane
ADEG_RS07535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADEG_RS07540	COG0101	tRNA pseudouridine synthase activity
ADEG_RS07545	COG0203	ribosomal protein L17
ADEG_RS07550	COG0202	RNA polymerase activity
ADEG_RS07555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADEG_RS07560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADEG_RS07570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADEG_RS07575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADEG_RS07585	COG0024	Methionine aminopeptidase
ADEG_RS07590	COG0201	protein transport
ADEG_RS07595	COG0200	Binds to the 23S rRNA
ADEG_RS07600	COG1841	ribosomal large subunit assembly
ADEG_RS07605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADEG_RS07610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADEG_RS07615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADEG_RS07620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADEG_RS07625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADEG_RS07630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADEG_RS07635	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADEG_RS07640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADEG_RS07645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADEG_RS07650	COG0255	Belongs to the universal ribosomal protein uL29 family
ADEG_RS07655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADEG_RS07660	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADEG_RS07665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADEG_RS07670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADEG_RS07675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADEG_RS07680	COG0089	rRNA binding
ADEG_RS07685	COG0088	Forms part of the polypeptide exit tunnel
ADEG_RS07690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADEG_RS07695	COG0051	transcription antitermination factor activity, RNA binding
ADEG_RS07700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADEG_RS07705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADEG_RS07710	COG0049	tRNA binding
ADEG_RS07715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADEG_RS07725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADEG_RS07730	COG0085	RNA polymerase activity
ADEG_RS07735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ADEG_RS07740	COG2894	cell division
ADEG_RS07745	COG0850	regulation of cytokinetic process
ADEG_RS07750	COG0735	belongs to the Fur family
ADEG_RS07770	COG1077	Cell shape determining protein MreB Mrl
ADEG_RS07775	COG2003	Belongs to the UPF0758 family
ADEG_RS07780	COG0424	maF-like protein
ADEG_RS07810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADEG_RS07820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADEG_RS07825	COG1873	PFAM PRC-barrel domain
ADEG_RS07835	COG1191	sigma factor activity
ADEG_RS07840	COG1191	sigma factor activity
ADEG_RS07850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADEG_RS07855	COG3856	small basic protein
ADEG_RS07875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADEG_RS07880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADEG_RS07885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADEG_RS07890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADEG_RS07895	COG0772	Belongs to the SEDS family
ADEG_RS07900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADEG_RS07905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADEG_RS07910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADEG_RS07915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADEG_RS07920	COG0768	penicillin binding
ADEG_RS07930	COG0275	rRNA processing
ADEG_RS07935	COG2001	Belongs to the MraZ family
ADEG_RS07950	COG0268	Binds directly to 16S ribosomal RNA
ADEG_RS07960	COG0011	TIGRFAM Protein of
ADEG_RS07975	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADEG_RS07980	COG0039	L-malate dehydrogenase activity
ADEG_RS07990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADEG_RS07995	COG0589	response to stress
ADEG_RS08020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADEG_RS08040	COG0683	leucine binding
ADEG_RS08055	COG1022	Amp-dependent synthetase and ligase
ADEG_RS08070	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ADEG_RS08080	COG2814	Major facilitator Superfamily
ADEG_RS08085	COG1809	phosphosulfolactate synthase activity
ADEG_RS08090	COG0564	pseudouridine synthase activity
ADEG_RS08095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADEG_RS08115	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ADEG_RS08125	COG2226	methyltransferase
ADEG_RS08130	COG0772	Belongs to the SEDS family
ADEG_RS08140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADEG_RS08145	COG0148	phosphopyruvate hydratase activity
ADEG_RS08150	COG0149	triose-phosphate isomerase activity
ADEG_RS08155	COG0126	phosphoglycerate kinase activity
ADEG_RS08170	COG1481	regulation of sporulation
ADEG_RS08175	COG0726	polysaccharide deacetylase
ADEG_RS08180	COG1660	Displays ATPase and GTPase activities
ADEG_RS08185	COG0166	Belongs to the GPI family
ADEG_RS08190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADEG_RS08205	COG0791	NLP P60 protein
ADEG_RS08205	COG1388	LysM domain
ADEG_RS08220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADEG_RS08225	COG2255	four-way junction helicase activity
ADEG_RS08230	COG0632	four-way junction helicase activity
ADEG_RS08235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADEG_RS08245	COG0217	transcriptional regulatory protein
ADEG_RS08250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADEG_RS08260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADEG_RS08290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADEG_RS08295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADEG_RS08305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADEG_RS08310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADEG_RS08315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADEG_RS08330	COG0756	dUTP diphosphatase activity
ADEG_RS08335	COG0612	Peptidase, M16
ADEG_RS08340	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADEG_RS08345	COG0726	polysaccharide deacetylase
ADEG_RS08350	COG1185	polyribonucleotide nucleotidyltransferase activity
ADEG_RS08355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADEG_RS08360	COG0196	riboflavin kinase activity
ADEG_RS08365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADEG_RS08375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADEG_RS08380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADEG_RS08380	COG3064	Membrane
ADEG_RS08390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ADEG_RS08395	COG0195	Participates in both transcription termination and antitermination
ADEG_RS08400	COG0779	Required for maturation of 30S ribosomal subunits
ADEG_RS08405	COG3118	belongs to the thioredoxin family
ADEG_RS08410	COG1396	sequence-specific DNA binding
ADEG_RS08415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADEG_RS08420	COG0456	acetyltransferase
ADEG_RS08430	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADEG_RS08435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADEG_RS08440	COG0124	histidyl-tRNA synthetase
ADEG_RS08445	COG1215	transferase activity, transferring glycosyl groups
ADEG_RS08450	COG1090	epimerase
ADEG_RS08455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADEG_RS08495	COG3854	ATPases associated with a variety of cellular activities
ADEG_RS08515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ADEG_RS08560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADEG_RS08565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADEG_RS08570	COG1461	Dihydroxyacetone kinase
ADEG_RS08575	COG1307	EDD domain protein, DegV family
ADEG_RS08580	COG0857	belongs to the CobB CobQ family
ADEG_RS08585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADEG_RS08585	COG1042	CoA-binding domain protein
ADEG_RS08585	COG0045	succinate-CoA ligase (ADP-forming) activity
ADEG_RS08590	COG3773	Cell wall hydrolase
ADEG_RS08600	COG3935	DnaD domain protein
ADEG_RS08630	COG0037	tRNA processing
ADEG_RS08645	COG2046	Belongs to the sulfate adenylyltransferase family
ADEG_RS08660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADEG_RS08700	COG1459	type II secretion system
ADEG_RS08710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADEG_RS08730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADEG_RS08735	COG0358	DNA primase activity
ADEG_RS08740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADEG_RS08745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADEG_RS08750	COG0574	Belongs to the PEP-utilizing enzyme family
ADEG_RS08750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADEG_RS08755	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADEG_RS08760	COG0517	IMP dehydrogenase activity
ADEG_RS08765	COG0751	glycine-tRNA ligase activity
ADEG_RS08770	COG0752	glycyl-tRNA synthetase alpha subunit
ADEG_RS08775	COG1381	Involved in DNA repair and RecF pathway recombination
ADEG_RS08815	COG2414	aldehyde ferredoxin oxidoreductase
ADEG_RS08820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADEG_RS08830	COG1937	Protein conserved in bacteria
ADEG_RS08870	COG1388	LysM domain
ADEG_RS08870	COG0791	NLP P60 protein
ADEG_RS08875	COG0617	tRNA 3'-terminal CCA addition
ADEG_RS08885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADEG_RS08890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADEG_RS08890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADEG_RS08895	COG0736	holo-[acyl-carrier-protein] synthase activity
ADEG_RS08900	COG3279	Response regulator of the LytR AlgR family
ADEG_RS08905	COG3275	phosphorelay sensor kinase activity
ADEG_RS08910	COG2217	Heavy metal translocating P-type atpase
ADEG_RS08925	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADEG_RS08930	COG1518	maintenance of DNA repeat elements
ADEG_RS08930	COG1468	defense response to virus
ADEG_RS08985	COG2378	regulation of single-species biofilm formation
ADEG_RS08995	COG3546	catalase activity
ADEG_RS09015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADEG_RS09055	COG1796	DNA polymerase
ADEG_RS09055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ADEG_RS09070	COG2814	Major facilitator Superfamily
ADEG_RS09075	COG1254	Belongs to the acylphosphatase family
ADEG_RS09085	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADEG_RS09115	COG0495	leucyl-tRNA aminoacylation
ADEG_RS09130	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADEG_RS09145	COG2198	Histidine kinase
ADEG_RS09145	COG0643	Histidine kinase
ADEG_RS09150	COG1366	Belongs to the anti-sigma-factor antagonist family
ADEG_RS09155	COG1366	Belongs to the anti-sigma-factor antagonist family
ADEG_RS09185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADEG_RS09200	COG1940	carbohydrate kinase activity
ADEG_RS09205	COG0561	phosphatase activity
ADEG_RS09210	COG0322	excinuclease ABC activity
ADEG_RS09215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADEG_RS09220	COG0556	nucleotide-excision repair
ADEG_RS09230	COG0165	Argininosuccinate lyase
ADEG_RS09235	COG0137	argininosuccinate synthase activity
ADEG_RS09240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADEG_RS09245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADEG_RS09250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADEG_RS09255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADEG_RS09260	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADEG_RS09270	COG0156	8-amino-7-oxononanoate synthase activity
ADEG_RS09280	COG3464	Transposase
ADEG_RS09315	COG1968	undecaprenyl-diphosphatase activity
ADEG_RS09320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADEG_RS09340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADEG_RS09350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADEG_RS09355	COG0492	ferredoxin-NADP+ reductase activity
ADEG_RS09360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADEG_RS09365	COG1414	Transcriptional regulator
ADEG_RS09380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADEG_RS09385	COG1980	fructose-bisphosphate aldolase activity
ADEG_RS09390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADEG_RS09395	COG3959	Transketolase, thiamine diphosphate binding domain
ADEG_RS09405	COG1850	ribulose-bisphosphate carboxylase activity
ADEG_RS09410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADEG_RS09430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADEG_RS09455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADEG_RS09460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ADEG_RS09465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADEG_RS09470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADEG_RS09475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADEG_RS09485	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADEG_RS09490	COG0535	radical SAM domain protein
ADEG_RS09495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADEG_RS09500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADEG_RS09505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADEG_RS09510	COG0247	lactate metabolic process
ADEG_RS09515	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADEG_RS09525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADEG_RS09530	COG0347	Belongs to the P(II) protein family
ADEG_RS09535	COG0004	ammonium transporteR
ADEG_RS09550	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADEG_RS09555	COG3005	denitrification pathway
ADEG_RS09560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADEG_RS09565	COG1333	cytochrome c biogenesis protein
ADEG_RS09575	COG0745	RESPONSE REGULATOR receiver
ADEG_RS09605	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADEG_RS09610	COG0348	domain, Protein
ADEG_RS09615	COG1151	hydroxylamine reductase activity
ADEG_RS09620	COG1959	2 iron, 2 sulfur cluster binding
ADEG_RS09635	COG1309	transcriptional regulator
ADEG_RS09650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADEG_RS09670	COG3344	reverse transcriptase
ADEG_RS09675	COG0500	methyltransferase
ADEG_RS09680	COG5416	Lipopolysaccharide assembly protein A domain
ADEG_RS09685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADEG_RS09690	COG0492	ferredoxin-NADP+ reductase activity
ADEG_RS09695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ADEG_RS09700	COG1923	regulation of RNA biosynthetic process
ADEG_RS09705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADEG_RS09710	COG2136	Putative SAM-dependent methyltransferase
ADEG_RS09710	COG2521	methyltransferase
ADEG_RS09715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADEG_RS09720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADEG_RS09725	COG0222	ribosome binding
ADEG_RS09730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADEG_RS09735	COG0081	regulation of translation
ADEG_RS09740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADEG_RS09745	COG0250	Participates in transcription elongation, termination and antitermination
ADEG_RS09750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADEG_RS09755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADEG_RS09765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADEG_RS09780	COG0798	PFAM Bile acid sodium symporter
ADEG_RS09785	COG0730	response to heat
ADEG_RS09795	COG0640	Transcriptional regulator
ADEG_RS09800	COG0537	adenosine 5'-monophosphoramidase activity
ADEG_RS09805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADEG_RS09810	COG1426	Protein conserved in bacteria
ADEG_RS09815	COG1674	ftsk spoiiie
ADEG_RS09835	COG0542	response to heat
ADEG_RS09840	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ADEG_RS09845	COG3880	PFAM UvrB UvrC protein
ADEG_RS09855	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADEG_RS09860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADEG_RS09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADEG_RS09900	COG0310	cobalt ion transport
ADEG_RS09905	COG0310	cobalt ion transport
ADEG_RS09910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADEG_RS09915	COG0473	3-isopropylmalate dehydrogenase activity
ADEG_RS09935	COG0728	peptidoglycan biosynthetic process
ADEG_RS09940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADEG_RS09945	COG2323	membrane
ADEG_RS09950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADEG_RS09955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADEG_RS09960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADEG_RS09965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADEG_RS09990	COG1924	4 iron, 4 sulfur cluster binding
ADEG_RS09995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADEG_RS10000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADEG_RS10005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADEG_RS10005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADEG_RS10015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADEG_RS10015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADEG_RS10020	COG0577	efflux transmembrane transporter activity
ADEG_RS10025	COG1136	(ABC) transporter
ADEG_RS10030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADEG_RS10050	COG0640	Transcriptional regulator
ADEG_RS10065	COG3464	Transposase
ADEG_RS10135	COG0309	Hydrogenase expression formation protein (HypE)
ADEG_RS10145	COG0298	carbon dioxide binding
ADEG_RS10150	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADEG_RS10155	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADEG_RS10160	COG0375	protein maturation
ADEG_RS10170	COG3259	Nickel-dependent hydrogenase
ADEG_RS10190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEG_RS10190	COG1776	CheC inhibitor of MCP methylation
ADEG_RS10195	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEG_RS10200	COG2201	protein-glutamate methylesterase activity
ADEG_RS10205	COG1776	CheC inhibitor of MCP methylation
ADEG_RS10210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ADEG_RS10215	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ADEG_RS10220	COG4786	Flagellar basal body rod
ADEG_RS10230	COG1191	sigma factor activity
ADEG_RS10245	COG1419	protein localization to endoplasmic reticulum
ADEG_RS10250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADEG_RS10255	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADEG_RS10260	COG1684	flagellar biosynthetic protein fliR
ADEG_RS10265	COG1987	bacterial-type flagellum assembly
ADEG_RS10270	COG1338	Plays a role in the flagellum-specific transport system
ADEG_RS10280	COG1776	CheC inhibitor of MCP methylation
ADEG_RS10280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEG_RS10290	COG4786	Flagellar basal body rod
ADEG_RS10310	COG1157	protein secretion by the type III secretion system
ADEG_RS10320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADEG_RS10325	COG1766	The M ring may be actively involved in energy transduction
ADEG_RS10330	COG1677	Flagellar hook-basal body complex protein FliE
ADEG_RS10340	COG1815	bacterial-type flagellum-dependent cell motility
ADEG_RS10350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADEG_RS10370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADEG_RS10375	COG0765	amino acid transport
ADEG_RS10380	COG1126	abc transporter atp-binding protein
ADEG_RS10390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ADEG_RS10395	COG0105	UTP biosynthetic process
ADEG_RS10400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADEG_RS10405	COG0037	tRNA processing
ADEG_RS10420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADEG_RS10455	COG3956	TIGRFAM MazG family protein
ADEG_RS10460	COG2002	toxin-antitoxin pair type II binding
ADEG_RS10465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADEG_RS10470	COG0193	aminoacyl-tRNA hydrolase activity
ADEG_RS10475	COG1333	cytochrome c biogenesis protein
ADEG_RS10480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADEG_RS10485	COG0535	radical SAM domain protein
ADEG_RS10495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADEG_RS10500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADEG_RS10505	COG0583	DNA-binding transcription factor activity
ADEG_RS10510	COG2391	methyltransferase activity
ADEG_RS10515	COG0425	Belongs to the sulfur carrier protein TusA family
ADEG_RS10575	COG2221	Nitrite and sulphite reductase 4Fe-4S
ADEG_RS10580	COG2221	Nitrite and sulphite reductase 4Fe-4S
ADEG_RS10585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADEG_RS10590	COG1802	Transcriptional regulator
ADEG_RS10595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADEG_RS10645	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ADEG_RS10650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADEG_RS10655	COG3583	domain protein
ADEG_RS10655	COG3584	3D domain protein
ADEG_RS10660	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ADEG_RS10665	COG0084	hydrolase, TatD family'
ADEG_RS10670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADEG_RS10670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADEG_RS10675	COG2002	toxin-antitoxin pair type II binding
ADEG_RS10680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADEG_RS10685	COG1774	PSP1 C-terminal conserved region
ADEG_RS10695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADEG_RS10700	COG1982	Orn Lys Arg decarboxylase major
ADEG_RS10720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADEG_RS10720	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADEG_RS10735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADEG_RS10740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADEG_RS10745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADEG_RS10780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADEG_RS10785	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ADEG_RS10790	COG0305	Participates in initiation and elongation during chromosome replication
ADEG_RS10795	COG0359	binds to the 23S rRNA
ADEG_RS10800	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADEG_RS10805	COG0629	single-stranded DNA binding
ADEG_RS10810	COG0360	Binds together with S18 to 16S ribosomal RNA
ADEG_RS10845	COG1475	DNA binding
ADEG_RS10850	COG1192	Involved in chromosome partitioning
ADEG_RS10855	COG0357	Ribosomal RNA small subunit methyltransferase G
ADEG_RS10860	COG1847	R3H domain protein
ADEG_RS10865	COG0706	membrane insertase activity
ADEG_RS10870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADEG_RS10875	COG0594	ribonuclease P activity
ADEG_RS11050	COG2959	enzyme of heme biosynthesis
ADEG_RS11060	COG1846	Transcriptional regulator
ADEG_RS11075	COG1361	Conserved repeat domain
ADEG_RS11080	COG2199	diguanylate cyclase activity
ADEG_RS11120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ADEG_RS11120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADEG_RS11140	COG3852	Histidine kinase
ADEG_RS11175	COG5002	protein histidine kinase activity
ADEG_RS11175	COG3850	Histidine kinase
ADEG_RS11185	COG0358	DNA primase activity
ADEG_RS11190	COG1396	sequence-specific DNA binding
ADEG_RS11235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADEG_RS11260	COG2861	carbohydrate metabolic process
ADEG_RS11285	COG1233	COG1233 Phytoene dehydrogenase and related
ADEG_RS11315	COG1215	transferase activity, transferring glycosyl groups
ADEG_RS11330	COG1429	ligase activity, forming nitrogen-metal bonds
ADEG_RS11340	COG5002	protein histidine kinase activity
ADEG_RS11340	COG3447	MASE1 domain protein
ADEG_RS11340	COG5001	Diguanylate cyclase
ADEG_RS11345	COG3706	GGDEF domain
ADEG_RS11405	COG0668	transmembrane transport
ADEG_RS11410	COG3706	GGDEF domain
ADEG_RS11420	COG5001	Diguanylate cyclase
ADEG_RS11420	COG5002	protein histidine kinase activity
ADEG_RS11425	COG2385	sporulation resulting in formation of a cellular spore
ADEG_RS11425	COG2247	cell wall binding repeat
ADEG_RS11440	COG0572	uridine kinase
ADEG_RS11460	COG1140	nitrate reductase beta subunit
ADEG_RS11475	COG5278	phosphoserine phosphatase activity
ADEG_RS11475	COG0840	transmembrane signaling receptor activity
ADEG_RS11485	COG0590	tRNA wobble adenosine to inosine editing