locus-tag	class	description
B737_RS00010	COG0592	DNA-directed DNA polymerase activity
B737_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B737_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B737_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B737_RS00030	COG0187	DNA topoisomerase II activity
B737_RS00180	COG0705	Rhomboid family
B737_RS00180	COG0457	Tetratricopeptide repeat
B737_RS00195	COG3764	Sortase (surface protein transpeptidase)
B737_RS00225	COG2197	response regulator
B737_RS00255	COG0515	serine threonine protein kinase
B737_RS00255	COG2815	serine threonine protein kinase
B737_RS00260	COG0515	serine threonine protein kinase
B737_RS00265	COG0768	penicillin binding
B737_RS00280	COG1716	ATPase activity
B737_RS00285	COG1716	ATPase activity
B737_RS00315	COG0626	cystathionine gamma-synthase activity
B737_RS00335	COG2186	Transcriptional regulator
B737_RS00340	COG0747	negative chemotaxis
B737_RS00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS00355	COG0444	Belongs to the ABC transporter superfamily
B737_RS00360	COG4608	Belongs to the ABC transporter superfamily
B737_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS00375	COG0154	amidase activity
B737_RS00380	COG3547	Transposase (IS116 IS110 IS902 family)
B737_RS00400	COG2301	Belongs to the HpcH HpaI aldolase family
B737_RS00410	COG0702	epimerase
B737_RS00415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B737_RS00430	COG1309	transcriptional regulator
B737_RS00440	COG2211	Major facilitator Superfamily
B737_RS00470	COG2372	response to copper ion
B737_RS00470	COG1276	copper resistance
B737_RS00485	COG1174	glycine betaine transport
B737_RS00495	COG1174	glycine betaine transport
B737_RS00520	COG2226	methyltransferase
B737_RS00530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B737_RS00535	COG0405	Gamma-glutamyltransferase
B737_RS00545	COG5433	transposase activity
B737_RS00560	COG0477	Major facilitator Superfamily
B737_RS00570	COG4585	Histidine kinase
B737_RS00575	COG2197	response regulator
B737_RS00605	COG0438	transferase activity, transferring glycosyl groups
B737_RS00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B737_RS00665	COG3275	phosphorelay sensor kinase activity
B737_RS00690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B737_RS00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B737_RS00695	COG0425	Belongs to the sulfur carrier protein TusA family
B737_RS00715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS00735	COG1191	sigma factor activity
B737_RS00825	COG1271	oxidase subunit
B737_RS00830	COG1294	oxidase, subunit
B737_RS00835	COG4988	ABC transporter
B737_RS00890	COG4715	Zinc finger, swim domain protein
B737_RS00900	COG1072	(Pantothenic acid kinase))
B737_RS00905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B737_RS00915	COG0406	alpha-ribazole phosphatase activity
B737_RS00950	COG0754	glutathionylspermidine amidase activity
B737_RS00960	COG0596	Alpha beta hydrolase
B737_RS00965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B737_RS00970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B737_RS00980	COG0579	oxidoreductase
B737_RS01005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B737_RS01020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B737_RS01050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B737_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS01065	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS01110	COG0561	phosphatase activity
B737_RS01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS01135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B737_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS01155	COG0277	FAD linked oxidase domain protein
B737_RS01165	COG1216	Glycosyl transferase, family 2
B737_RS01195	COG1216	Glycosyl transferase, family 2
B737_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS01220	COG0604	alcohol dehydrogenase
B737_RS01220	COG3321	synthase
B737_RS01225	COG2234	aminopeptidase activity
B737_RS01285	COG4565	transcriptional regulatory protein
B737_RS01290	COG3290	protein histidine kinase activity
B737_RS01295	COG1116	anion transmembrane transporter activity
B737_RS01320	COG1672	PFAM Archaeal ATPase
B737_RS01320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B737_RS01335	COG1522	sequence-specific DNA binding
B737_RS01340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS01350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS01355	COG2186	Transcriptional regulator
B737_RS01370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B737_RS01380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS01410	COG3469	chitinase activity
B737_RS01415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B737_RS01440	COG3584	3D domain protein
B737_RS01440	COG3583	domain protein
B737_RS01515	COG3559	Exporter of polyketide antibiotics
B737_RS01520	COG1131	(ABC) transporter
B737_RS01575	COG0287	Prephenate dehydrogenase
B737_RS01580	COG0446	pyridine nucleotide-disulphide oxidoreductase
B737_RS01580	COG1902	pentaerythritol trinitrate reductase activity
B737_RS01600	COG1846	Transcriptional regulator
B737_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B737_RS01645	COG2318	DinB family
B737_RS01655	COG0194	GDP metabolic process
B737_RS01715	COG0515	serine threonine protein kinase
B737_RS01730	COG0028	Belongs to the TPP enzyme family
B737_RS01745	COG3199	ATP-NAD kinase
B737_RS01750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B737_RS01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B737_RS01770	COG0515	serine threonine protein kinase
B737_RS01780	COG0477	Major facilitator Superfamily
B737_RS01790	COG1595	DNA-templated transcription, initiation
B737_RS01805	COG1278	Cold shock
B737_RS01980	COG2226	methyltransferase
B737_RS02020	COG2233	PERMEase
B737_RS02025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B737_RS02035	COG1414	Transcriptional regulator
B737_RS02055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B737_RS02145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B737_RS02170	COG2364	Membrane
B737_RS02175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS02190	COG2733	membrane
B737_RS02210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B737_RS02245	COG2986	histidine ammonia-lyase
B737_RS02275	COG1174	glycine betaine transport
B737_RS02290	COG1846	Transcriptional regulator
B737_RS02300	COG2130	NADP-dependent
B737_RS02315	COG1064	alcohol dehydrogenase
B737_RS02345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B737_RS02360	COG0438	transferase activity, transferring glycosyl groups
B737_RS02375	COG0588	phosphoglycerate mutase activity
B737_RS02385	COG0667	Aldo Keto reductase
B737_RS02390	COG5002	protein histidine kinase activity
B737_RS02420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B737_RS02440	COG4585	Histidine kinase
B737_RS02465	COG1595	DNA-templated transcription, initiation
B737_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS02485	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B737_RS02490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B737_RS02495	COG0181	hydroxymethylbilane synthase activity
B737_RS02500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B737_RS02500	COG1648	precorrin-2 dehydrogenase activity
B737_RS02535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B737_RS02540	COG0577	efflux transmembrane transporter activity
B737_RS02540	COG1136	(ABC) transporter
B737_RS02545	COG1136	(ABC) transporter
B737_RS02545	COG0577	efflux transmembrane transporter activity
B737_RS02560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B737_RS02565	COG0406	alpha-ribazole phosphatase activity
B737_RS02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B737_RS02575	COG0785	Cytochrome C biogenesis protein
B737_RS02585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B737_RS02605	COG1522	sequence-specific DNA binding
B737_RS02635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B737_RS02660	COG0438	transferase activity, transferring glycosyl groups
B737_RS02675	COG2226	methyltransferase
B737_RS02690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B737_RS02695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B737_RS02700	COG0649	NAD binding
B737_RS02715	COG1034	ATP synthesis coupled electron transport
B737_RS02720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B737_RS02725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B737_RS02730	COG0839	Belongs to the complex I subunit 6 family
B737_RS02735	COG0713	ATP synthesis coupled electron transport
B737_RS02740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B737_RS02750	COG1007	ATP synthesis coupled electron transport
B737_RS02780	COG0142	geranyltranstransferase activity
B737_RS02795	COG1013	pyruvate-flavodoxin oxidoreductase activity
B737_RS02800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B737_RS02800	COG0674	pyruvate-flavodoxin oxidoreductase activity
B737_RS02810	COG1522	sequence-specific DNA binding
B737_RS02815	COG1834	amidinotransferase
B737_RS02830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B737_RS02835	COG0438	transferase activity, transferring glycosyl groups
B737_RS02850	COG0367	asparagine synthase
B737_RS02895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B737_RS02900	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B737_RS02910	COG1215	transferase activity, transferring glycosyl groups
B737_RS02920	COG4310	Domain of unknown function (DUF2172)
B737_RS02935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B737_RS02950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS02965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS02970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS02990	COG1666	GTP binding
B737_RS03010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B737_RS03040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B737_RS03045	COG2030	dehydratase
B737_RS03065	COG1725	Transcriptional regulator
B737_RS03095	COG0081	regulation of translation
B737_RS03100	COG2267	carboxylic ester hydrolase activity
B737_RS03130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B737_RS03155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B737_RS03180	COG0673	inositol 2-dehydrogenase activity
B737_RS03200	COG0604	alcohol dehydrogenase
B737_RS03200	COG3321	synthase
B737_RS03220	COG0604	alcohol dehydrogenase
B737_RS03220	COG3321	synthase
B737_RS03240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B737_RS03245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B737_RS03260	COG0546	phosphoglycolate phosphatase activity
B737_RS03270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS03275	COG0657	acetylesterase activity
B737_RS03280	COG0477	Major facilitator Superfamily
B737_RS03295	COG2124	cytochrome p450
B737_RS03300	COG2124	cytochrome p450
B737_RS03320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B737_RS03335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS03360	COG2124	cytochrome p450
B737_RS03370	COG3959	Transketolase, thiamine diphosphate binding domain
B737_RS03375	COG3958	Transketolase
B737_RS03385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B737_RS03400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B737_RS03410	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B737_RS03415	COG1522	sequence-specific DNA binding
B737_RS03420	COG0477	Major facilitator Superfamily
B737_RS03430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS03430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B737_RS03475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B737_RS03480	COG0049	tRNA binding
B737_RS03485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B737_RS03495	COG0051	transcription antitermination factor activity, RNA binding
B737_RS03500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B737_RS03505	COG0088	Forms part of the polypeptide exit tunnel
B737_RS03510	COG0089	rRNA binding
B737_RS03515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B737_RS03520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B737_RS03525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B737_RS03530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B737_RS03535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B737_RS03540	COG0255	Belongs to the universal ribosomal protein uL29 family
B737_RS03545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B737_RS03550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B737_RS03555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B737_RS03560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B737_RS03570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B737_RS03575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B737_RS03580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B737_RS03585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B737_RS03590	COG1841	ribosomal large subunit assembly
B737_RS03595	COG0200	Binds to the 23S rRNA
B737_RS03605	COG1280	lysine exporter protein (LysE YggA)
B737_RS03615	COG0563	adenylate kinase activity
B737_RS03625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B737_RS03630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B737_RS03645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B737_RS03650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B737_RS03655	COG0202	RNA polymerase activity
B737_RS03660	COG0203	ribosomal protein L17
B737_RS03665	COG0101	tRNA pseudouridine synthase activity
B737_RS03700	COG1404	Belongs to the peptidase S8 family
B737_RS03710	COG1674	ftsk spoiiie
B737_RS03715	COG0443	Heat shock 70 kDa protein
B737_RS03745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B737_RS03750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B737_RS03755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B737_RS03765	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS03805	COG1349	DNA-binding transcription factor activity
B737_RS03810	COG1070	Carbohydrate kinase
B737_RS03815	COG3842	ATPase activity
B737_RS03820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B737_RS03830	COG0802	atpase or kinase
B737_RS03840	COG0825	malonyl-CoA metabolic process
B737_RS03840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B737_RS03845	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS03855	COG0456	acetyltransferase
B737_RS03860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B737_RS03865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B737_RS03885	COG1215	transferase activity, transferring glycosyl groups
B737_RS03895	COG2226	methyltransferase
B737_RS03905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B737_RS03910	COG0798	PFAM Bile acid sodium symporter
B737_RS03915	COG0640	Transcriptional regulator
B737_RS03925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B737_RS03930	COG0459	protein refolding
B737_RS03980	COG0516	GMP reductase activity
B737_RS04000	COG0277	FAD linked oxidase domain protein
B737_RS04005	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS04025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B737_RS04025	COG0519	Catalyzes the synthesis of GMP from XMP
B737_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS04060	COG0697	spore germination
B737_RS04065	COG0583	DNA-binding transcription factor activity
B737_RS04075	COG2815	serine threonine protein kinase
B737_RS04075	COG0515	serine threonine protein kinase
B737_RS04125	COG0045	succinate-CoA ligase (ADP-forming) activity
B737_RS04150	COG0138	bifunctional purine biosynthesis protein purh
B737_RS04190	COG0587	DNA-directed DNA polymerase activity
B737_RS04210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B737_RS04220	COG2814	Major facilitator Superfamily
B737_RS04225	COG0640	Transcriptional regulator
B737_RS04230	COG2814	Major facilitator Superfamily
B737_RS04240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B737_RS04265	COG2226	methyltransferase
B737_RS04300	COG1234	tRNA 3'-trailer cleavage
B737_RS04315	COG0180	Tryptophanyl-tRNA synthetase
B737_RS04325	COG1295	ribonuclease BN
B737_RS04340	COG1686	Belongs to the peptidase S11 family
B737_RS04360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B737_RS04375	COG2009	succinate dehydrogenase
B737_RS04380	COG3345	alpha-galactosidase
B737_RS04385	COG1082	Xylose isomerase domain protein TIM barrel
B737_RS04390	COG1744	ABC transporter substrate-binding protein PnrA-like
B737_RS04395	COG3845	ABC transporter
B737_RS04405	COG1079	Belongs to the binding-protein-dependent transport system permease family
B737_RS04425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B737_RS04430	COG2271	Major facilitator Superfamily
B737_RS04450	COG1733	regulation of RNA biosynthetic process
B737_RS04460	COG1063	alcohol dehydrogenase
B737_RS04475	COG0395	ABC-type sugar transport system, permease component
B737_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS04515	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS04520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B737_RS04560	COG0789	Transcriptional regulator
B737_RS04565	COG0667	Aldo Keto reductase
B737_RS04585	COG0475	glutathione-regulated potassium exporter activity
B737_RS04590	COG0745	RESPONSE REGULATOR receiver
B737_RS04595	COG2205	protein histidine kinase activity
B737_RS04615	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS04640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B737_RS04670	COG0515	serine threonine protein kinase
B737_RS04695	COG1473	amidohydrolase
B737_RS04695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS04735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B737_RS04740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B737_RS04745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B737_RS04780	COG4770	biotin carboxylase activity
B737_RS04795	COG1301	dicarboxylic acid transport
B737_RS04800	COG0424	maF-like protein
B737_RS04805	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS04825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS04830	COG1846	Transcriptional regulator
B737_RS04840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B737_RS04855	COG4585	Histidine kinase
B737_RS04875	COG1309	transcriptional regulator
B737_RS04885	COG1733	regulation of RNA biosynthetic process
B737_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS04910	COG0583	DNA-binding transcription factor activity
B737_RS04925	COG2226	methyltransferase
B737_RS04940	COG1902	pentaerythritol trinitrate reductase activity
B737_RS04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
B737_RS04960	COG4585	Histidine kinase
B737_RS04965	COG2197	response regulator
B737_RS04970	COG3103	Sh3 type 3 domain protein
B737_RS04970	COG0791	NLP P60 protein
B737_RS04970	COG1388	LysM domain
B737_RS04985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B737_RS05000	COG3537	Alpha-1,2-mannosidase
B737_RS05005	COG0483	inositol monophosphate 1-phosphatase activity
B737_RS05015	COG2205	protein histidine kinase activity
B737_RS05020	COG2197	response regulator
B737_RS05025	COG2197	response regulator
B737_RS05090	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS05130	COG0702	epimerase
B737_RS05135	COG1316	TRANSCRIPTIONal
B737_RS05140	COG1316	TRANSCRIPTIONal
B737_RS05170	COG0438	transferase activity, transferring glycosyl groups
B737_RS05205	COG1725	Transcriptional regulator
B737_RS05220	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B737_RS05220	COG0778	Nitroreductase
B737_RS05225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B737_RS05315	COG1611	Belongs to the LOG family
B737_RS05330	COG1216	Glycosyl transferase, family 2
B737_RS05355	COG0463	Glycosyl transferase, family 2
B737_RS05360	COG1132	(ABC) transporter
B737_RS05365	COG4988	ABC transporter
B737_RS05370	COG1294	oxidase, subunit
B737_RS05375	COG1271	oxidase subunit
B737_RS05400	COG2818	Glycosylase
B737_RS05405	COG1024	Enoyl-CoA hydratase
B737_RS05415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B737_RS05420	COG0583	DNA-binding transcription factor activity
B737_RS05425	COG2814	Major facilitator Superfamily
B737_RS05435	COG4122	O-methyltransferase activity
B737_RS05440	COG1595	DNA-templated transcription, initiation
B737_RS05450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS05455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B737_RS05470	COG2239	Acts as a magnesium transporter
B737_RS05480	COG0330	HflC and HflK could
B737_RS05530	COG1309	transcriptional regulator
B737_RS05540	COG2197	response regulator
B737_RS05545	COG4585	Histidine kinase
B737_RS05575	COG0598	Magnesium transport protein CorA
B737_RS05605	COG0613	PHP domain protein
B737_RS05610	COG2095	MarC family integral membrane protein
B737_RS05635	COG0513	Belongs to the DEAD box helicase family
B737_RS05665	COG2267	carboxylic ester hydrolase activity
B737_RS05670	COG1309	transcriptional regulator
B737_RS05675	COG2267	carboxylic ester hydrolase activity
B737_RS05695	COG0243	molybdopterin cofactor binding
B737_RS05700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B737_RS05710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B737_RS05710	COG2146	nitrite reductase [NAD(P)H] activity
B737_RS05715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B737_RS05715	COG2146	nitrite reductase [NAD(P)H] activity
B737_RS05740	COG2378	regulation of single-species biofilm formation
B737_RS05800	COG0714	Associated with various cellular activities
B737_RS05825	COG2321	neutral zinc metallopeptidase
B737_RS05845	COG0612	Peptidase, M16
B737_RS05865	COG1175	transmembrane transport
B737_RS05870	COG0395	ABC-type sugar transport system, permease component
B737_RS05875	COG1486	melibiose metabolic process
B737_RS05890	COG0640	Transcriptional regulator
B737_RS05905	COG3265	gluconokinase activity
B737_RS05915	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B737_RS05950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B737_RS05970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B737_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS06090	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS06095	COG3842	ATPase activity
B737_RS06100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B737_RS06105	COG1176	ABC-type spermidine putrescine transport system, permease component I
B737_RS06110	COG1177	transmembrane transport
B737_RS06115	COG0596	Alpha beta hydrolase
B737_RS06120	COG1968	undecaprenyl-diphosphatase activity
B737_RS06130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B737_RS06135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B737_RS06135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B737_RS06145	COG2318	DinB family
B737_RS06160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B737_RS06160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B737_RS06165	COG0653	protein targeting
B737_RS06185	COG0174	glutamine synthetase
B737_RS06190	COG0154	amidase activity
B737_RS06210	COG1522	sequence-specific DNA binding
B737_RS06220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B737_RS06220	COG0519	Catalyzes the synthesis of GMP from XMP
B737_RS06230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B737_RS06240	COG0174	glutamine synthetase
B737_RS06300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B737_RS06320	COG3480	Lon protease (S16) C-terminal proteolytic domain
B737_RS06360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B737_RS06365	COG2884	Cell division ATP-binding protein ftsE
B737_RS06370	COG2177	Part of the ABC transporter FtsEX involved in
B737_RS06375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B737_RS06400	COG2197	response regulator
B737_RS06405	COG4585	Histidine kinase
B737_RS06415	COG3706	GGDEF domain
B737_RS06430	COG2986	histidine ammonia-lyase
B737_RS06435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B737_RS06445	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS06450	COG1228	amidohydrolase
B737_RS06455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS06490	COG4585	Histidine kinase
B737_RS06520	COG1131	(ABC) transporter
B737_RS06525	COG1643	Atp-dependent helicase
B737_RS06530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B737_RS06550	COG0791	NLP P60 protein
B737_RS06550	COG3883	PFAM NLP P60 protein
B737_RS06565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS06575	COG2318	DinB family
B737_RS06580	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS06590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B737_RS06595	COG0187	DNA topoisomerase II activity
B737_RS06640	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS06645	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS06650	COG1129	ABC transporter
B737_RS06655	COG1879	ABC-type sugar transport system periplasmic component
B737_RS06660	COG1609	Transcriptional regulator
B737_RS06665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B737_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS06695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B737_RS06725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B737_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS06765	COG0017	Asparaginyl-tRNA synthetase
B737_RS06785	COG0596	Alpha beta hydrolase
B737_RS06810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS06815	COG1486	melibiose metabolic process
B737_RS06825	COG1053	succinate dehydrogenase
B737_RS06830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS06835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B737_RS06845	COG0596	Alpha beta hydrolase
B737_RS06935	COG0697	spore germination
B737_RS06940	COG1846	Transcriptional regulator
B737_RS06975	COG3903	Transcriptional regulator
B737_RS06975	COG3629	intracellular signal transduction
B737_RS06985	COG2211	Major facilitator Superfamily
B737_RS06995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B737_RS07000	COG0411	ABC transporter
B737_RS07025	COG1309	transcriptional regulator
B737_RS07055	COG1136	(ABC) transporter
B737_RS07110	COG0477	Major facilitator Superfamily
B737_RS07125	COG3387	PFAM Glycoside hydrolase 15-related
B737_RS07130	COG1063	alcohol dehydrogenase
B737_RS07150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS07200	COG3209	COG3209 Rhs family protein
B737_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS07235	COG0604	alcohol dehydrogenase
B737_RS07235	COG3321	synthase
B737_RS07265	COG2018	Roadblock/LC7 domain
B737_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS07295	COG0583	DNA-binding transcription factor activity
B737_RS07300	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS07345	COG0667	Aldo Keto reductase
B737_RS07355	COG1595	DNA-templated transcription, initiation
B737_RS07385	COG3629	intracellular signal transduction
B737_RS07385	COG3903	Transcriptional regulator
B737_RS07395	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B737_RS07410	COG0604	alcohol dehydrogenase
B737_RS07425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B737_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS07475	COG1234	tRNA 3'-trailer cleavage
B737_RS07485	COG3852	Histidine kinase
B737_RS07490	COG2272	Belongs to the type-B carboxylesterase lipase family
B737_RS07530	COG3547	Transposase (IS116 IS110 IS902 family)
B737_RS07540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B737_RS07620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B737_RS07625	COG0765	amino acid transport
B737_RS07630	COG1126	abc transporter atp-binding protein
B737_RS07635	COG2964	Protein conserved in bacteria
B737_RS07655	COG1131	(ABC) transporter
B737_RS07685	COG2186	Transcriptional regulator
B737_RS07690	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS07695	COG1129	ABC transporter
B737_RS07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS07720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS07735	COG1879	ABC-type sugar transport system periplasmic component
B737_RS07755	COG3629	intracellular signal transduction
B737_RS07755	COG3903	Transcriptional regulator
B737_RS07765	COG3540	Alkaline phosphatase
B737_RS07775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B737_RS07785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
B737_RS07790	COG1940	carbohydrate kinase activity
B737_RS07810	COG4221	oxidoreductase activity
B737_RS07815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B737_RS07835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS07850	COG0513	Belongs to the DEAD box helicase family
B737_RS07875	COG2183	response to ionizing radiation
B737_RS07920	COG1309	transcriptional regulator
B737_RS07935	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS07935	COG2030	dehydratase
B737_RS07940	COG3396	Phenylacetate-CoA oxygenase
B737_RS07945	COG3460	Phenylacetate-CoA oxygenase
B737_RS07950	COG3396	Phenylacetate-CoA oxygenase
B737_RS07955	COG2151	metal-sulfur cluster biosynthetic enzyme
B737_RS07960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B737_RS07975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B737_RS07990	COG0604	alcohol dehydrogenase
B737_RS08005	COG0346	lactoylglutathione lyase activity
B737_RS08010	COG0183	Belongs to the thiolase family
B737_RS08025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS08030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B737_RS08035	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B737_RS08040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B737_RS08050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B737_RS08060	COG3279	Response regulator of the LytR AlgR family
B737_RS08065	COG3275	phosphorelay sensor kinase activity
B737_RS08075	COG1879	ABC-type sugar transport system periplasmic component
B737_RS08080	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS08095	COG1609	Transcriptional regulator
B737_RS08100	COG3537	Alpha-1,2-mannosidase
B737_RS08105	COG3537	Alpha-1,2-mannosidase
B737_RS08115	COG1846	Transcriptional regulator
B737_RS08140	COG0058	SHG alpha-glucan phosphorylase activity
B737_RS08165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS08180	COG1119	ATPase activity
B737_RS08185	COG1024	Enoyl-CoA hydratase
B737_RS08190	COG2226	methyltransferase
B737_RS08210	COG3979	chitinase
B737_RS08220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS08255	COG0667	Aldo Keto reductase
B737_RS08260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS08265	COG0791	NLP P60 protein
B737_RS08265	COG3883	PFAM NLP P60 protein
B737_RS08270	COG1957	nucleoside hydrolase
B737_RS08315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B737_RS08350	COG3250	beta-galactosidase activity
B737_RS08355	COG0386	Belongs to the glutathione peroxidase family
B737_RS08365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B737_RS08375	COG1307	EDD domain protein, DegV family
B737_RS08385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B737_RS08400	COG0604	alcohol dehydrogenase
B737_RS08405	COG2197	response regulator
B737_RS08420	COG0482	sulfurtransferase activity
B737_RS08440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS08460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B737_RS08475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B737_RS08480	COG0154	amidase activity
B737_RS08485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B737_RS08510	COG0673	inositol 2-dehydrogenase activity
B737_RS08520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B737_RS08530	COG0129	dihydroxy-acid dehydratase activity
B737_RS08545	COG0440	acetolactate synthase activity
B737_RS08550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B737_RS08590	COG1404	Belongs to the peptidase S8 family
B737_RS08595	COG0473	3-isopropylmalate dehydrogenase activity
B737_RS08600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B737_RS08605	COG0179	Fumarylacetoacetate (FAA) hydrolase
B737_RS08635	COG3903	Transcriptional regulator
B737_RS08635	COG3629	intracellular signal transduction
B737_RS08690	COG0776	regulation of translation
B737_RS08700	COG0420	3'-5' exonuclease activity
B737_RS08705	COG0419	ATPase involved in DNA repair
B737_RS08715	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS08740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B737_RS08745	COG0066	3-isopropylmalate dehydratase activity
B737_RS08755	COG3903	Transcriptional regulator
B737_RS08755	COG3629	intracellular signal transduction
B737_RS08770	COG1920	GTP binding
B737_RS08780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B737_RS08790	COG0252	asparaginase activity
B737_RS08800	COG1477	protein flavinylation
B737_RS08815	COG0745	RESPONSE REGULATOR receiver
B737_RS08820	COG2205	protein histidine kinase activity
B737_RS08830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS08860	COG3345	alpha-galactosidase
B737_RS08865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B737_RS08870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B737_RS08880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B737_RS08885	COG1461	Dihydroxyacetone kinase
B737_RS08915	COG1404	Belongs to the peptidase S8 family
B737_RS08920	COG5433	transposase activity
B737_RS09000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B737_RS09025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B737_RS09035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS09040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS09050	COG0542	response to heat
B737_RS09055	COG4249	Peptidase C14 caspase catalytic subunit p20
B737_RS09055	COG2319	Wd-40 repeat
B737_RS09060	COG3973	AAA domain
B737_RS09065	COG0742	ribosomal rna small subunit methyltransferase
B737_RS09070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B737_RS09100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B737_RS09105	COG0571	ribonuclease III activity
B737_RS09115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B737_RS09135	COG3386	PFAM SMP-30 Gluconolaconase
B737_RS09165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B737_RS09170	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS09190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B737_RS09190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B737_RS09195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B737_RS09200	COG0509	glycine decarboxylation via glycine cleavage system
B737_RS09205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B737_RS09210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B737_RS09215	COG1760	l-serine dehydratase
B737_RS09225	COG2442	InterPro IPR007367
B737_RS09235	COG2186	Transcriptional regulator
B737_RS09245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B737_RS09250	COG4122	O-methyltransferase activity
B737_RS09255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS09285	COG0789	Transcriptional regulator
B737_RS09295	COG2814	Major facilitator Superfamily
B737_RS09300	COG0179	Fumarylacetoacetate (FAA) hydrolase
B737_RS09305	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS09315	COG1879	ABC-type sugar transport system periplasmic component
B737_RS09320	COG1129	ABC transporter
B737_RS09325	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS09330	COG2186	Transcriptional regulator
B737_RS09375	COG1929	Belongs to the glycerate kinase type-1 family
B737_RS09380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B737_RS09390	COG1940	carbohydrate kinase activity
B737_RS09395	COG1653	transport
B737_RS09405	COG0395	ABC-type sugar transport system, permease component
B737_RS09410	COG3345	alpha-galactosidase
B737_RS09415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B737_RS09420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B737_RS09425	COG0183	Belongs to the thiolase family
B737_RS09430	COG3485	protocatechuate 3,4-dioxygenase
B737_RS09435	COG3485	protocatechuate 3,4-dioxygenase
B737_RS09440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B737_RS09450	COG1414	Transcriptional regulator
B737_RS09455	COG0746	molybdenum cofactor guanylyltransferase activity
B737_RS09460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B737_RS09500	COG3706	GGDEF domain
B737_RS09510	COG0667	Aldo Keto reductase
B737_RS09535	COG3962	Belongs to the TPP enzyme family
B737_RS09540	COG3718	enzyme involved in inositol metabolism
B737_RS09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS09570	COG1082	Xylose isomerase domain protein TIM barrel
B737_RS09575	COG1609	Transcriptional regulator
B737_RS09580	COG0673	inositol 2-dehydrogenase activity
B737_RS09585	COG0367	asparagine synthase
B737_RS09595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B737_RS09600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B737_RS09605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B737_RS09640	COG1254	Belongs to the acylphosphatase family
B737_RS09655	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B737_RS09660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B737_RS09680	COG1414	Transcriptional regulator
B737_RS09685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B737_RS09720	COG3835	regulator
B737_RS09740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS09745	COG3345	alpha-galactosidase
B737_RS09750	COG1309	transcriptional regulator
B737_RS09780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B737_RS09785	COG4266	Belongs to the allantoicase family
B737_RS09790	COG1832	CoA-binding protein
B737_RS09795	COG2873	o-acetylhomoserine
B737_RS09815	COG1595	DNA-templated transcription, initiation
B737_RS09840	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B737_RS09860	COG3706	GGDEF domain
B737_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS09870	COG1309	transcriptional regulator
B737_RS09880	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B737_RS09890	COG1132	(ABC) transporter
B737_RS09915	COG0228	four-way junction DNA binding
B737_RS09935	COG0336	Belongs to the RNA methyltransferase TrmD family
B737_RS09940	COG0335	large ribosomal subunit rRNA binding
B737_RS09945	COG0681	Belongs to the peptidase S26 family
B737_RS09950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B737_RS09960	COG0792	nuclease activity
B737_RS09985	COG1191	sigma factor activity
B737_RS09995	COG0052	Belongs to the universal ribosomal protein uS2 family
B737_RS10000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B737_RS10005	COG0528	UMP kinase activity
B737_RS10010	COG0233	cytoplasmic translational termination
B737_RS10030	COG1695	Transcriptional regulator
B737_RS10035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B737_RS10045	COG1120	ATPase activity
B737_RS10050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B737_RS10055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B737_RS10065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B737_RS10115	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS10130	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS10170	COG0789	Transcriptional regulator
B737_RS10190	COG3795	YCII-related domain
B737_RS10195	COG0702	epimerase
B737_RS10210	COG1476	TRANSCRIPTIONal
B737_RS10220	COG3795	YCII-related domain
B737_RS10225	COG4941	Belongs to the sigma-70 factor family
B737_RS10245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B737_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS10270	COG0596	Alpha beta hydrolase
B737_RS10280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B737_RS10290	COG2814	Major facilitator Superfamily
B737_RS10295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B737_RS10305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B737_RS10310	COG0750	zinc metalloprotease
B737_RS10315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B737_RS10345	COG0454	-acetyltransferase
B737_RS10345	COG0456	acetyltransferase
B737_RS10380	COG2186	Transcriptional regulator
B737_RS10415	COG0513	Belongs to the DEAD box helicase family
B737_RS10450	COG0583	DNA-binding transcription factor activity
B737_RS10460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B737_RS10465	COG3022	response to hydroperoxide
B737_RS10500	COG0442	prolyl-tRNA aminoacylation
B737_RS10515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B737_RS10570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B737_RS10570	COG1017	nitric oxide dioxygenase activity
B737_RS10585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B737_RS10605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B737_RS10635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS10655	COG4152	abc transporter atp-binding protein
B737_RS10660	COG1668	transmembrane transport
B737_RS10670	COG3201	nicotinamide mononucleotide transporter
B737_RS10675	COG1620	l-lactate permease
B737_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS10695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B737_RS10820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B737_RS10850	COG0477	Major facilitator Superfamily
B737_RS10870	COG1960	acyl-CoA dehydrogenase activity
B737_RS10880	COG1104	cysteine desulfurase activity
B737_RS10890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B737_RS10910	COG1113	amino acid transport
B737_RS10915	COG2186	Transcriptional regulator
B737_RS10920	COG0587	DNA-directed DNA polymerase activity
B737_RS10925	COG0477	Major facilitator Superfamily
B737_RS10950	COG1376	ErfK ybiS ycfS ynhG family protein
B737_RS10960	COG0586	Pfam SNARE associated Golgi protein
B737_RS10965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B737_RS10980	COG1309	transcriptional regulator
B737_RS10990	COG0321	lipoyl(octanoyl) transferase activity
B737_RS11000	COG1090	epimerase
B737_RS11010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B737_RS11060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B737_RS11070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B737_RS11070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B737_RS11085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B737_RS11090	COG0667	Aldo Keto reductase
B737_RS11110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS11120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B737_RS11155	COG1845	cytochrome c oxidase, subunit III
B737_RS11160	COG2010	Cytochrome c
B737_RS11170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B737_RS11205	COG0438	transferase activity, transferring glycosyl groups
B737_RS11220	COG2124	cytochrome p450
B737_RS11225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B737_RS11230	COG0659	secondary active sulfate transmembrane transporter activity
B737_RS11235	COG0659	secondary active sulfate transmembrane transporter activity
B737_RS11240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B737_RS11260	COG0501	Belongs to the peptidase M48B family
B737_RS11265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B737_RS11275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B737_RS11280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B737_RS11285	COG0157	Belongs to the NadC ModD family
B737_RS11290	COG1404	Belongs to the peptidase S8 family
B737_RS11330	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS11350	COG1674	ftsk spoiiie
B737_RS11375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B737_RS11385	COG5520	Belongs to the glycosyl hydrolase 30 family
B737_RS11400	COG4566	intracellular signal transduction
B737_RS11405	COG2197	response regulator
B737_RS11415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B737_RS11425	COG0131	Imidazoleglycerol-phosphate dehydratase
B737_RS11440	COG2267	carboxylic ester hydrolase activity
B737_RS11445	COG2409	Drug exporters of the RND superfamily
B737_RS11450	COG1309	transcriptional regulator
B737_RS11455	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B737_RS11465	COG3959	Transketolase, thiamine diphosphate binding domain
B737_RS11470	COG3958	Transketolase
B737_RS11485	COG1960	acyl-CoA dehydrogenase activity
B737_RS11495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B737_RS11500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B737_RS11560	COG0107	imidazoleglycerol-phosphate synthase activity
B737_RS11570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B737_RS11605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B737_RS11615	COG0134	indole-3-glycerol-phosphate synthase activity
B737_RS11620	COG0133	tryptophan synthase activity
B737_RS11625	COG0159	tryptophan synthase activity
B737_RS11630	COG0789	Transcriptional regulator
B737_RS11650	COG0174	glutamine synthetase
B737_RS11665	COG1473	amidohydrolase
B737_RS11670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B737_RS11680	COG0067	glutamate synthase
B737_RS11680	COG0070	glutamate synthase
B737_RS11680	COG0069	glutamate synthase activity
B737_RS11705	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B737_RS11730	COG2268	Band 7 protein
B737_RS11740	COG0515	serine threonine protein kinase
B737_RS11740	COG2815	serine threonine protein kinase
B737_RS11770	COG0142	geranyltranstransferase activity
B737_RS11825	COG0242	peptide deformylase activity
B737_RS11830	COG1201	RNA secondary structure unwinding
B737_RS11835	COG1349	DNA-binding transcription factor activity
B737_RS11845	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B737_RS11855	COG0443	Heat shock 70 kDa protein
B737_RS11865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B737_RS11870	COG2137	regulation of response to DNA damage stimulus
B737_RS11890	COG0800	Aldolase
B737_RS11910	COG1053	succinate dehydrogenase
B737_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS11945	COG0765	amino acid transport
B737_RS11950	COG0765	amino acid transport
B737_RS11955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B737_RS11960	COG1126	abc transporter atp-binding protein
B737_RS11965	COG0745	RESPONSE REGULATOR receiver
B737_RS11970	COG3850	Histidine kinase
B737_RS11970	COG0642	Histidine kinase
B737_RS11980	COG1733	regulation of RNA biosynthetic process
B737_RS12045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B737_RS12060	COG1196	nuclear chromosome segregation
B737_RS12065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B737_RS12075	COG0525	valine-tRNA ligase activity
B737_RS12090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B737_RS12100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B737_RS12110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B737_RS12115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B737_RS12135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B737_RS12145	COG1505	serine-type exopeptidase activity
B737_RS12180	COG2936	dipeptidyl-peptidase activity
B737_RS12185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B737_RS12195	COG2197	response regulator
B737_RS12200	COG4585	Histidine kinase
B737_RS12215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B737_RS12220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B737_RS12235	COG0123	including yeast histone deacetylase and acetoin utilization protein
B737_RS12250	COG1960	acyl-CoA dehydrogenase activity
B737_RS12255	COG1960	acyl-CoA dehydrogenase activity
B737_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS12275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B737_RS12280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B737_RS12330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS12345	COG1609	Transcriptional regulator
B737_RS12360	COG0395	ABC-type sugar transport system, permease component
B737_RS12365	COG2723	6-phospho-beta-galactosidase activity
B737_RS12390	COG0003	Pfam Anion-transporting ATPase
B737_RS12400	COG1940	carbohydrate kinase activity
B737_RS12415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS12440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B737_RS12475	COG0640	Transcriptional regulator
B737_RS12495	COG1946	Acyl-CoA thioesterase
B737_RS12515	COG2197	response regulator
B737_RS12520	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS12535	COG1960	acyl-CoA dehydrogenase activity
B737_RS12540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS12565	COG1566	PFAM secretion protein HlyD family protein
B737_RS12580	COG1309	transcriptional regulator
B737_RS12585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B737_RS12600	COG2018	Roadblock/LC7 domain
B737_RS12630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B737_RS12630	COG1703	isobutyryl-CoA mutase activity
B737_RS12630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B737_RS12640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS12645	COG1309	transcriptional regulator
B737_RS12650	COG1960	acyl-CoA dehydrogenase activity
B737_RS12655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B737_RS12665	COG0657	acetylesterase activity
B737_RS12670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS12675	COG0748	coenzyme F420 binding
B737_RS12685	COG1960	acyl-CoA dehydrogenase activity
B737_RS12690	COG1960	acyl-CoA dehydrogenase activity
B737_RS12695	COG2030	dehydratase
B737_RS12715	COG0196	riboflavin kinase activity
B737_RS12720	COG2030	dehydratase
B737_RS12740	COG1053	succinate dehydrogenase
B737_RS12750	COG1960	acyl-CoA dehydrogenase activity
B737_RS12755	COG2267	carboxylic ester hydrolase activity
B737_RS12760	COG0346	lactoylglutathione lyase activity
B737_RS12765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B737_RS12790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B737_RS12810	COG0583	DNA-binding transcription factor activity
B737_RS12820	COG0446	pyridine nucleotide-disulphide oxidoreductase
B737_RS12870	COG1473	amidohydrolase
B737_RS12880	COG1228	amidohydrolase
B737_RS12885	COG0596	Alpha beta hydrolase
B737_RS12890	COG0183	Belongs to the thiolase family
B737_RS12895	COG2124	cytochrome p450
B737_RS12910	COG1295	ribonuclease BN
B737_RS12940	COG2070	2-Nitropropane dioxygenase
B737_RS12955	COG2188	Transcriptional regulator
B737_RS12975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B737_RS12975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B737_RS12985	COG1490	D-aminoacyl-tRNA deacylase activity
B737_RS12990	COG2890	protein-(glutamine-N5) methyltransferase activity
B737_RS13010	COG2313	pseudouridylate synthase activity
B737_RS13035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B737_RS13050	COG4213	ABC transporter substrate-binding protein
B737_RS13060	COG4214	carbohydrate transport
B737_RS13090	COG0531	amino acid
B737_RS13120	COG0366	Alpha amylase catalytic
B737_RS13125	COG0366	Alpha amylase catalytic
B737_RS13135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B737_RS13150	COG1940	carbohydrate kinase activity
B737_RS13155	COG0483	inositol monophosphate 1-phosphatase activity
B737_RS13175	COG0756	dUTP diphosphatase activity
B737_RS13205	COG0569	domain protein
B737_RS13210	COG0531	amino acid
B737_RS13215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B737_RS13225	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS13230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B737_RS13235	COG1609	Transcriptional regulator
B737_RS13245	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS13250	COG0028	Belongs to the TPP enzyme family
B737_RS13270	COG0745	RESPONSE REGULATOR receiver
B737_RS13275	COG2205	protein histidine kinase activity
B737_RS13280	COG0657	acetylesterase activity
B737_RS13295	COG1024	Enoyl-CoA hydratase
B737_RS13295	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS13300	COG0183	Belongs to the thiolase family
B737_RS13335	COG0531	amino acid
B737_RS13350	COG2197	response regulator
B737_RS13360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B737_RS13370	COG3253	May function as heme-dependent peroxidase
B737_RS13375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS13385	COG3220	belongs to the UPF0276 family
B737_RS13400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B737_RS13430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS13435	COG0539	negative regulation of cytoplasmic translation
B737_RS13445	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B737_RS13445	COG2508	Transcriptional regulator
B737_RS13450	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS13455	COG0506	proline dehydrogenase activity
B737_RS13460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B737_RS13470	COG3795	YCII-related domain
B737_RS13480	COG4941	Belongs to the sigma-70 factor family
B737_RS13490	COG1793	dna ligase
B737_RS13515	COG1302	Protein conserved in bacteria
B737_RS13525	COG1595	DNA-templated transcription, initiation
B737_RS13560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B737_RS13565	COG0640	Transcriptional regulator
B737_RS13575	COG2326	polyphosphate kinase activity
B737_RS13590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B737_RS13595	COG1993	acr, cog1993
B737_RS13600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B737_RS13630	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B737_RS13630	COG1672	PFAM Archaeal ATPase
B737_RS13655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B737_RS13680	COG2124	cytochrome p450
B737_RS13700	COG2084	Dehydrogenase
B737_RS13715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B737_RS13725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B737_RS13730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B737_RS13735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B737_RS13740	COG1309	transcriptional regulator
B737_RS13750	COG1073	alpha beta
B737_RS13760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B737_RS13770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B737_RS13775	COG1263	PTS System
B737_RS13780	COG2188	Transcriptional regulator
B737_RS13785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B737_RS13790	COG2190	(PTS) system
B737_RS13790	COG1263	PTS System
B737_RS13790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B737_RS13815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B737_RS13820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B737_RS13825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B737_RS13830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B737_RS13835	COG0346	lactoylglutathione lyase activity
B737_RS13850	COG0006	proline dipeptidase activity
B737_RS13855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B737_RS13860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B737_RS13880	COG0540	Belongs to the ATCase OTCase family
B737_RS13895	COG0505	Belongs to the CarA family
B737_RS13900	COG0419	ATPase involved in DNA repair
B737_RS13915	COG0284	orotidine-5'-phosphate decarboxylase activity
B737_RS13925	COG0194	GDP metabolic process
B737_RS13930	COG1758	RNA polymerase activity
B737_RS13940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B737_RS13965	COG0405	Gamma-glutamyltransferase
B737_RS13970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B737_RS13995	COG2197	response regulator
B737_RS14000	COG4585	Histidine kinase
B737_RS14015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B737_RS14015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B737_RS14020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B737_RS14040	COG0322	excinuclease ABC activity
B737_RS14045	COG1660	Displays ATPase and GTPase activities
B737_RS14055	COG1481	regulation of sporulation
B737_RS14060	COG0463	Glycosyl transferase, family 2
B737_RS14085	COG3250	beta-galactosidase activity
B737_RS14090	COG0408	coproporphyrinogen oxidase activity
B737_RS14130	COG1280	lysine exporter protein (LysE YggA)
B737_RS14140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B737_RS14145	COG0126	phosphoglycerate kinase activity
B737_RS14150	COG0149	triose-phosphate isomerase activity
B737_RS14170	COG0363	glucosamine-6-phosphate deaminase activity
B737_RS14185	COG0166	Belongs to the GPI family
B737_RS14190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B737_RS14200	COG0109	protoheme IX farnesyltransferase activity
B737_RS14305	COG0396	ATPase activity
B737_RS14320	COG2151	metal-sulfur cluster biosynthetic enzyme
B737_RS14330	COG1742	UPF0060 membrane protein
B737_RS14340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B737_RS14350	COG4585	Histidine kinase
B737_RS14360	COG2226	methyltransferase
B737_RS14395	COG0457	Tetratricopeptide repeat
B737_RS14455	COG0488	(ABC) transporter
B737_RS14480	COG1132	(ABC) transporter
B737_RS14485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B737_RS14490	COG4821	SIS domain
B737_RS14500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B737_RS14505	COG1316	TRANSCRIPTIONal
B737_RS14510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B737_RS14520	COG3300	MHYT domain
B737_RS14520	COG5001	Diguanylate cyclase
B737_RS14535	COG1051	belongs to the nudix hydrolase family
B737_RS14545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B737_RS14545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B737_RS14555	COG1024	Enoyl-CoA hydratase
B737_RS14580	COG1960	acyl-CoA dehydrogenase activity
B737_RS14585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B737_RS14600	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS14625	COG3469	chitinase activity
B737_RS14660	COG1309	transcriptional regulator
B737_RS14665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS14675	COG3693	PFAM glycoside hydrolase, family 10
B737_RS14705	COG1309	transcriptional regulator
B737_RS14710	COG0789	Transcriptional regulator
B737_RS14725	COG2319	Wd-40 repeat
B737_RS14725	COG4249	Peptidase C14 caspase catalytic subunit p20
B737_RS14740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS14805	COG2197	response regulator
B737_RS14870	COG0300	oxidoreductase activity
B737_RS14880	COG1846	Transcriptional regulator
B737_RS14895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B737_RS14910	COG1595	DNA-templated transcription, initiation
B737_RS14920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B737_RS14930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B737_RS14935	COG1799	cell septum assembly
B737_RS14945	COG3599	regulation of cell shape
B737_RS14955	COG0640	Transcriptional regulator
B737_RS14960	COG0477	Major facilitator Superfamily
B737_RS14965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B737_RS14975	COG0640	Transcriptional regulator
B737_RS14980	COG3263	regulation of cellular component size
B737_RS14985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B737_RS14995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B737_RS15020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS15030	COG0248	Ppx GppA phosphatase
B737_RS15075	COG1940	carbohydrate kinase activity
B737_RS15075	COG1846	Transcriptional regulator
B737_RS15085	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B737_RS15110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS15110	COG2010	Cytochrome c
B737_RS15135	COG1309	transcriptional regulator
B737_RS15140	COG4221	oxidoreductase activity
B737_RS15145	COG0667	Aldo Keto reductase
B737_RS15150	COG0542	response to heat
B737_RS15160	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B737_RS15170	COG0514	ATP-dependent DNA helicase (RecQ)
B737_RS15180	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS15215	COG2205	protein histidine kinase activity
B737_RS15220	COG0745	RESPONSE REGULATOR receiver
B737_RS15230	COG0076	glutamate decarboxylase activity
B737_RS15285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B737_RS15295	COG1131	(ABC) transporter
B737_RS15315	COG0604	alcohol dehydrogenase
B737_RS15325	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B737_RS15345	COG4585	Histidine kinase
B737_RS15355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS15360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B737_RS15365	COG2080	2 iron, 2 sulfur cluster binding
B737_RS15390	COG2188	Transcriptional regulator
B737_RS15400	COG1063	alcohol dehydrogenase
B737_RS15415	COG2172	sigma factor antagonist activity
B737_RS15420	COG1366	Belongs to the anti-sigma-factor antagonist family
B737_RS15425	COG1366	Belongs to the anti-sigma-factor antagonist family
B737_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS15455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B737_RS15465	COG3546	catalase activity
B737_RS15475	COG0702	epimerase
B737_RS15480	COG1733	regulation of RNA biosynthetic process
B737_RS15505	COG1609	Transcriptional regulator
B737_RS15515	COG1175	transmembrane transport
B737_RS15520	COG0395	ABC-type sugar transport system, permease component
B737_RS15540	COG0667	Aldo Keto reductase
B737_RS15550	COG0667	Aldo Keto reductase
B737_RS15560	COG2378	regulation of single-species biofilm formation
B737_RS15570	COG1691	(AIR) carboxylase
B737_RS15575	COG3875	lactate racemase activity
B737_RS15580	COG3618	amidohydrolase
B737_RS15585	COG0179	Fumarylacetoacetate (FAA) hydrolase
B737_RS15590	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS15605	COG1129	ABC transporter
B737_RS15645	COG1609	Transcriptional regulator
B737_RS15650	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS15670	COG3251	PFAM MbtH domain protein
B737_RS15690	COG2124	cytochrome p450
B737_RS15715	COG0604	alcohol dehydrogenase
B737_RS15730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B737_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS15805	COG3250	beta-galactosidase activity
B737_RS15825	COG1309	transcriptional regulator
B737_RS15830	COG0596	Alpha beta hydrolase
B737_RS15840	COG1960	acyl-CoA dehydrogenase activity
B737_RS15845	COG1960	acyl-CoA dehydrogenase activity
B737_RS15870	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS15885	COG0395	ABC-type sugar transport system, permease component
B737_RS15890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B737_RS15895	COG0515	serine threonine protein kinase
B737_RS15930	COG2814	Major facilitator Superfamily
B737_RS15940	COG2205	protein histidine kinase activity
B737_RS15945	COG0745	RESPONSE REGULATOR receiver
B737_RS15960	COG1131	(ABC) transporter
B737_RS15980	COG1309	transcriptional regulator
B737_RS15990	COG1136	(ABC) transporter
B737_RS16005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B737_RS16010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS16020	COG1595	DNA-templated transcription, initiation
B737_RS16040	COG0596	Alpha beta hydrolase
B737_RS16050	COG0477	Major facilitator Superfamily
B737_RS16095	COG0366	Alpha amylase catalytic
B737_RS16110	COG0395	ABC-type sugar transport system, permease component
B737_RS16115	COG1175	transmembrane transport
B737_RS16130	COG1349	DNA-binding transcription factor activity
B737_RS16140	COG1609	Transcriptional regulator
B737_RS16145	COG0515	serine threonine protein kinase
B737_RS16145	COG2815	serine threonine protein kinase
B737_RS16150	COG0515	serine threonine protein kinase
B737_RS16150	COG2815	serine threonine protein kinase
B737_RS16165	COG0437	4 iron, 4 sulfur cluster binding
B737_RS16170	COG0243	molybdopterin cofactor binding
B737_RS16170	COG3383	formate dehydrogenase (NAD+) activity
B737_RS16175	COG0243	molybdopterin cofactor binding
B737_RS16180	COG2271	Major facilitator Superfamily
B737_RS16195	COG2318	DinB family
B737_RS16225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B737_RS16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS16240	COG0583	DNA-binding transcription factor activity
B737_RS16250	COG1053	succinate dehydrogenase
B737_RS16255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B737_RS16290	COG3511	phospholipase C
B737_RS16325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B737_RS16330	COG3938	Belongs to the proline racemase family
B737_RS16340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS16340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS16345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS16355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B737_RS16360	COG0395	ABC-type sugar transport system, permease component
B737_RS16365	COG1175	transmembrane transport
B737_RS16415	COG0628	permease
B737_RS16420	COG3507	Belongs to the glycosyl hydrolase 43 family
B737_RS16425	COG1793	dna ligase
B737_RS16425	COG3285	dna ligase
B737_RS16440	COG2226	methyltransferase
B737_RS16480	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS16485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS16490	COG1024	Enoyl-CoA hydratase
B737_RS16505	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS16575	COG3507	Belongs to the glycosyl hydrolase 43 family
B737_RS16645	COG1309	transcriptional regulator
B737_RS16650	COG1595	DNA-templated transcription, initiation
B737_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS16670	COG0028	Belongs to the TPP enzyme family
B737_RS16690	COG2018	Roadblock/LC7 domain
B737_RS16710	COG2188	Transcriptional regulator
B737_RS16715	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B737_RS16720	COG0395	ABC-type sugar transport system, permease component
B737_RS16725	COG1175	transmembrane transport
B737_RS16730	COG2182	Extracellular solute-binding protein
B737_RS16740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B737_RS16785	COG1609	Transcriptional regulator
B737_RS16815	COG3591	Belongs to the peptidase S1B family
B737_RS16840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B737_RS16870	COG2267	carboxylic ester hydrolase activity
B737_RS16900	COG2357	RelA SpoT domain protein
B737_RS16925	COG1280	lysine exporter protein (LysE YggA)
B737_RS16930	COG0484	heat shock protein binding
B737_RS16935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS16960	COG2409	Drug exporters of the RND superfamily
B737_RS16970	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS16980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B737_RS17020	COG1024	Enoyl-CoA hydratase
B737_RS17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS17045	COG0183	Belongs to the thiolase family
B737_RS17055	COG1960	acyl-CoA dehydrogenase activity
B737_RS17060	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS17065	COG1024	Enoyl-CoA hydratase
B737_RS17070	COG1960	acyl-CoA dehydrogenase activity
B737_RS17075	COG1960	acyl-CoA dehydrogenase activity
B737_RS17080	COG1960	acyl-CoA dehydrogenase activity
B737_RS17095	COG1802	Transcriptional regulator
B737_RS17100	COG3591	Belongs to the peptidase S1B family
B737_RS17100	COG1864	DNA RNA non-specific endonuclease
B737_RS17115	COG1063	alcohol dehydrogenase
B737_RS17120	COG2267	carboxylic ester hydrolase activity
B737_RS17140	COG1309	transcriptional regulator
B737_RS17145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS17160	COG3345	alpha-galactosidase
B737_RS17175	COG1175	transmembrane transport
B737_RS17180	COG0395	ABC-type sugar transport system, permease component
B737_RS17205	COG5640	endopeptidase activity
B737_RS17215	COG0477	Major facilitator Superfamily
B737_RS17225	COG1940	carbohydrate kinase activity
B737_RS17230	COG0531	amino acid
B737_RS17235	COG3250	beta-galactosidase activity
B737_RS17240	COG1940	carbohydrate kinase activity
B737_RS17250	COG1609	Transcriptional regulator
B737_RS17265	COG2124	cytochrome p450
B737_RS17305	COG1846	Transcriptional regulator
B737_RS17310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS17360	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS17390	COG0702	epimerase
B737_RS17415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B737_RS17430	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS17450	COG0601	transmembrane transport
B737_RS17455	COG0444	Belongs to the ABC transporter superfamily
B737_RS17460	COG4608	Belongs to the ABC transporter superfamily
B737_RS17470	COG0477	Major facilitator Superfamily
B737_RS17505	COG0477	Major facilitator Superfamily
B737_RS17515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B737_RS17530	COG0604	alcohol dehydrogenase
B737_RS17530	COG3321	synthase
B737_RS17535	COG3507	Belongs to the glycosyl hydrolase 43 family
B737_RS17550	COG1231	oxidoreductase activity
B737_RS17560	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B737_RS17560	COG0235	Class ii aldolase
B737_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS17580	COG0701	Predicted permease
B737_RS17605	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS17615	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS17635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B737_RS17670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B737_RS17700	COG0501	Belongs to the peptidase M48B family
B737_RS17735	COG0475	glutathione-regulated potassium exporter activity
B737_RS17735	COG0569	domain protein
B737_RS17770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B737_RS17775	COG4279	zinc finger
B737_RS17810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS17840	COG0069	glutamate synthase activity
B737_RS17845	COG0745	RESPONSE REGULATOR receiver
B737_RS17850	COG5002	protein histidine kinase activity
B737_RS17865	COG1136	(ABC) transporter
B737_RS17865	COG0577	efflux transmembrane transporter activity
B737_RS17870	COG0577	efflux transmembrane transporter activity
B737_RS17870	COG1136	(ABC) transporter
B737_RS17885	COG2814	Major facilitator Superfamily
B737_RS17890	COG0596	Alpha beta hydrolase
B737_RS17900	COG4585	Histidine kinase
B737_RS17930	COG4585	Histidine kinase
B737_RS17975	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B737_RS18020	COG0702	epimerase
B737_RS18045	COG0745	RESPONSE REGULATOR receiver
B737_RS18050	COG2205	protein histidine kinase activity
B737_RS18070	COG0726	polysaccharide deacetylase
B737_RS18120	COG0604	alcohol dehydrogenase
B737_RS18185	COG4221	oxidoreductase activity
B737_RS18190	COG4249	Peptidase C14 caspase catalytic subunit p20
B737_RS18190	COG2319	Wd-40 repeat
B737_RS18260	COG2197	response regulator
B737_RS18265	COG0736	holo-[acyl-carrier-protein] synthase activity
B737_RS18340	COG1834	amidinotransferase
B737_RS18350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS18355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B737_RS18360	COG2080	2 iron, 2 sulfur cluster binding
B737_RS18370	COG3345	alpha-galactosidase
B737_RS18410	COG1309	transcriptional regulator
B737_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS18445	COG0583	DNA-binding transcription factor activity
B737_RS18470	COG3250	beta-galactosidase activity
B737_RS18515	COG0596	Alpha beta hydrolase
B737_RS18520	COG0583	DNA-binding transcription factor activity
B737_RS18610	COG2205	protein histidine kinase activity
B737_RS18675	COG1522	sequence-specific DNA binding
B737_RS18685	COG4221	oxidoreductase activity
B737_RS18685	COG3321	synthase
B737_RS18685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS18685	COG0604	alcohol dehydrogenase
B737_RS18740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS18750	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B737_RS18755	COG2080	2 iron, 2 sulfur cluster binding
B737_RS18790	COG0631	protein serine/threonine phosphatase activity
B737_RS18830	COG3509	depolymerase
B737_RS18850	COG0601	transmembrane transport
B737_RS18860	COG4608	Belongs to the ABC transporter superfamily
B737_RS18870	COG1609	Transcriptional regulator
B737_RS18875	COG4124	Belongs to the glycosyl hydrolase 26 family
B737_RS18885	COG1940	carbohydrate kinase activity
B737_RS18885	COG1846	Transcriptional regulator
B737_RS18895	COG1960	acyl-CoA dehydrogenase activity
B737_RS18900	COG2207	Transcriptional regulator
B737_RS18970	COG0745	RESPONSE REGULATOR receiver
B737_RS18975	COG2205	protein histidine kinase activity
B737_RS18985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B737_RS18985	COG2755	lipolytic protein G-D-S-L family
B737_RS19000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B737_RS19000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B737_RS19010	COG2267	carboxylic ester hydrolase activity
B737_RS19015	COG2226	methyltransferase
B737_RS19025	COG0640	Transcriptional regulator
B737_RS19060	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B737_RS19070	COG0375	protein maturation
B737_RS19080	COG0409	Hydrogenase expression formation protein
B737_RS19125	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B737_RS19135	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B737_RS19170	COG3903	Transcriptional regulator
B737_RS19170	COG3629	intracellular signal transduction
B737_RS19175	COG0596	Alpha beta hydrolase
B737_RS19180	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS19180	COG1024	Enoyl-CoA hydratase
B737_RS19185	COG1733	regulation of RNA biosynthetic process
B737_RS19210	COG3321	synthase
B737_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS19210	COG0604	alcohol dehydrogenase
B737_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS19220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS19230	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS19260	COG0411	ABC transporter
B737_RS19270	COG1024	Enoyl-CoA hydratase
B737_RS19275	COG1960	acyl-CoA dehydrogenase activity
B737_RS19280	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS19285	COG1946	Acyl-CoA thioesterase
B737_RS19295	COG1024	Enoyl-CoA hydratase
B737_RS19300	COG1960	acyl-CoA dehydrogenase activity
B737_RS19305	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS19315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS19320	COG0183	Belongs to the thiolase family
B737_RS19360	COG1946	Acyl-CoA thioesterase
B737_RS19380	COG1960	acyl-CoA dehydrogenase activity
B737_RS19400	COG0183	Belongs to the thiolase family
B737_RS19415	COG0183	Belongs to the thiolase family
B737_RS19420	COG1024	Enoyl-CoA hydratase
B737_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS19450	COG1024	Enoyl-CoA hydratase
B737_RS19460	COG1960	acyl-CoA dehydrogenase activity
B737_RS19465	COG1960	acyl-CoA dehydrogenase activity
B737_RS19495	COG1960	acyl-CoA dehydrogenase activity
B737_RS19510	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS19515	COG1960	acyl-CoA dehydrogenase activity
B737_RS19520	COG1960	acyl-CoA dehydrogenase activity
B737_RS19525	COG1024	Enoyl-CoA hydratase
B737_RS19530	COG2188	Transcriptional regulator
B737_RS19535	COG0300	oxidoreductase activity
B737_RS19540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B737_RS19570	COG1309	transcriptional regulator
B737_RS19580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS19585	COG3629	intracellular signal transduction
B737_RS19585	COG3903	Transcriptional regulator
B737_RS19605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B737_RS19605	COG1017	nitric oxide dioxygenase activity
B737_RS19610	COG1846	Transcriptional regulator
B737_RS19610	COG1940	carbohydrate kinase activity
B737_RS19630	COG0531	amino acid
B737_RS19635	COG3387	PFAM Glycoside hydrolase 15-related
B737_RS19640	COG2814	Major facilitator Superfamily
B737_RS19655	COG2197	response regulator
B737_RS19690	COG0628	permease
B737_RS19705	COG1486	melibiose metabolic process
B737_RS19710	COG0395	ABC-type sugar transport system, permease component
B737_RS19730	COG1349	DNA-binding transcription factor activity
B737_RS19735	COG2222	sugar isomerase
B737_RS19750	COG1105	Belongs to the carbohydrate kinase PfkB family
B737_RS19825	COG0596	Alpha beta hydrolase
B737_RS19835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B737_RS19835	COG1024	Enoyl-CoA hydratase
B737_RS19840	COG3903	Transcriptional regulator
B737_RS19840	COG3629	intracellular signal transduction
B737_RS19850	COG1132	(ABC) transporter
B737_RS19875	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS19895	COG4221	oxidoreductase activity
B737_RS19900	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS19905	COG0395	ABC-type sugar transport system, permease component
B737_RS19910	COG3833	ABC-type maltose transport systems, permease component
B737_RS19945	COG2124	cytochrome p450
B737_RS19950	COG2175	clavaminate synthase activity
B737_RS19955	COG4221	oxidoreductase activity
B737_RS19955	COG3321	synthase
B737_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS19955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS19960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS20010	COG1940	carbohydrate kinase activity
B737_RS20015	COG1940	carbohydrate kinase activity
B737_RS20015	COG1846	Transcriptional regulator
B737_RS20020	COG1129	ABC transporter
B737_RS20025	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS20035	COG0673	inositol 2-dehydrogenase activity
B737_RS20045	COG0604	alcohol dehydrogenase
B737_RS20120	COG1064	alcohol dehydrogenase
B737_RS20125	COG1309	transcriptional regulator
B737_RS20130	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS20145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B737_RS20150	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS20170	COG2508	Transcriptional regulator
B737_RS20175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B737_RS20185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS20190	COG0463	Glycosyl transferase, family 2
B737_RS20200	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS20210	COG3629	intracellular signal transduction
B737_RS20215	COG0583	DNA-binding transcription factor activity
B737_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS20235	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS20240	COG1846	Transcriptional regulator
B737_RS20245	COG3903	Transcriptional regulator
B737_RS20245	COG3629	intracellular signal transduction
B737_RS20250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS20265	COG2197	response regulator
B737_RS20275	COG0577	efflux transmembrane transporter activity
B737_RS20275	COG1136	(ABC) transporter
B737_RS20305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B737_RS20335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B737_RS20350	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS20360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B737_RS20365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B737_RS20370	COG3903	Transcriptional regulator
B737_RS20370	COG3629	intracellular signal transduction
B737_RS20375	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B737_RS20395	COG3509	depolymerase
B737_RS20400	COG2205	protein histidine kinase activity
B737_RS20405	COG0745	RESPONSE REGULATOR receiver
B737_RS20410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B737_RS20420	COG0583	DNA-binding transcription factor activity
B737_RS20445	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS20475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B737_RS20520	COG0142	geranyltranstransferase activity
B737_RS20540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B737_RS20565	COG0395	ABC-type sugar transport system, permease component
B737_RS20580	COG1609	Transcriptional regulator
B737_RS20610	COG0653	protein targeting
B737_RS20635	COG2208	phosphoserine phosphatase activity
B737_RS20635	COG2172	sigma factor antagonist activity
B737_RS20635	COG1366	Belongs to the anti-sigma-factor antagonist family
B737_RS20655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS20665	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B737_RS20685	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B737_RS20690	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS20695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B737_RS20730	COG3661	Belongs to the glycosyl hydrolase 67 family
B737_RS20745	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS20790	COG2201	protein-glutamate methylesterase activity
B737_RS20795	COG2201	protein-glutamate methylesterase activity
B737_RS20815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B737_RS20860	COG0477	Major facilitator Superfamily
B737_RS20875	COG2318	DinB family
B737_RS20880	COG1793	dna ligase
B737_RS20910	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B737_RS20920	COG2814	Major facilitator Superfamily
B737_RS20930	COG2855	membrane
B737_RS20940	COG0583	DNA-binding transcription factor activity
B737_RS20970	COG0439	Biotin carboxylase
B737_RS21010	COG0477	Major facilitator Superfamily
B737_RS21035	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS21060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B737_RS21080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS21115	COG3285	dna ligase
B737_RS21115	COG1793	dna ligase
B737_RS21130	COG0657	acetylesterase activity
B737_RS21145	COG2267	carboxylic ester hydrolase activity
B737_RS21180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B737_RS21195	COG3634	alkyl hydroperoxide reductase activity
B737_RS21215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B737_RS21275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B737_RS21290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B737_RS21300	COG2890	protein-(glutamine-N5) methyltransferase activity
B737_RS21320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B737_RS21325	COG2124	cytochrome p450
B737_RS21335	COG2201	protein-glutamate methylesterase activity
B737_RS21350	COG2815	serine threonine protein kinase
B737_RS21350	COG0515	serine threonine protein kinase
B737_RS21360	COG0326	Molecular chaperone. Has ATPase activity
B737_RS21370	COG3794	PFAM blue (type 1) copper domain protein
B737_RS21435	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS21450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B737_RS21475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B737_RS21485	COG0300	oxidoreductase activity
B737_RS21490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B737_RS21490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B737_RS21495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B737_RS21500	COG2192	nodulation
B737_RS21505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B737_RS21520	COG0463	Glycosyl transferase, family 2
B737_RS21520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B737_RS21525	COG0297	glycogen (starch) synthase activity
B737_RS21570	COG1295	ribonuclease BN
B737_RS21570	COG1959	2 iron, 2 sulfur cluster binding
B737_RS21595	COG0723	plastoquinol--plastocyanin reductase activity
B737_RS21595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B737_RS21600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B737_RS21605	COG2890	protein-(glutamine-N5) methyltransferase activity
B737_RS21620	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS21630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS21640	COG1982	Orn Lys Arg decarboxylase major
B737_RS21660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS21685	COG0596	Alpha beta hydrolase
B737_RS21710	COG3835	regulator
B737_RS21735	COG3284	Transcriptional regulator
B737_RS21780	COG0459	protein refolding
B737_RS21810	COG0596	Alpha beta hydrolase
B737_RS21815	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS21820	COG0435	Glutathione S-transferase
B737_RS21830	COG2353	YceI-like domain
B737_RS21835	COG1309	transcriptional regulator
B737_RS21850	COG0395	ABC-type sugar transport system, permease component
B737_RS21855	COG1175	transmembrane transport
B737_RS21865	COG1609	Transcriptional regulator
B737_RS21870	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS21880	COG2124	cytochrome p450
B737_RS21890	COG1716	ATPase activity
B737_RS21890	COG5001	Diguanylate cyclase
B737_RS21905	COG0247	lactate metabolic process
B737_RS21905	COG2181	nitrate reductase activity
B737_RS21910	COG1716	ATPase activity
B737_RS21920	COG0477	Major facilitator Superfamily
B737_RS21930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B737_RS21935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B737_RS21935	COG1082	Xylose isomerase domain protein TIM barrel
B737_RS21940	COG2182	Extracellular solute-binding protein
B737_RS21945	COG1175	transmembrane transport
B737_RS21950	COG0395	ABC-type sugar transport system, permease component
B737_RS21955	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS21965	COG4991	sh3 domain protein
B737_RS22045	COG0302	gtp cyclohydrolase
B737_RS22060	COG1609	Transcriptional regulator
B737_RS22080	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS22095	COG1686	Belongs to the peptidase S11 family
B737_RS22105	COG1609	Transcriptional regulator
B737_RS22110	COG1879	ABC-type sugar transport system periplasmic component
B737_RS22120	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS22125	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS22145	COG2160	L-arabinose isomerase activity
B737_RS22155	COG1129	ABC transporter
B737_RS22160	COG4214	carbohydrate transport
B737_RS22170	COG1609	Transcriptional regulator
B737_RS22180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B737_RS22185	COG1414	Transcriptional regulator
B737_RS22195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B737_RS22200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B737_RS22210	COG0137	argininosuccinate synthase activity
B737_RS22255	COG0277	FAD linked oxidase domain protein
B737_RS22260	COG1609	Transcriptional regulator
B737_RS22270	COG1653	transport
B737_RS22275	COG1175	transmembrane transport
B737_RS22280	COG0395	ABC-type sugar transport system, permease component
B737_RS22290	COG0673	inositol 2-dehydrogenase activity
B737_RS22295	COG0673	inositol 2-dehydrogenase activity
B737_RS22305	COG3866	Pectate lyase
B737_RS22335	COG3629	intracellular signal transduction
B737_RS22335	COG3903	Transcriptional regulator
B737_RS22350	COG0589	response to stress
B737_RS22355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B737_RS22415	COG1090	epimerase
B737_RS22440	COG0297	glycogen (starch) synthase activity
B737_RS22465	COG3250	beta-galactosidase activity
B737_RS22480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B737_RS22525	COG0477	Major facilitator Superfamily
B737_RS22530	COG3321	synthase
B737_RS22530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B737_RS22530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B737_RS22535	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS22550	COG0300	oxidoreductase activity
B737_RS22555	COG1819	glycosyl
B737_RS22565	COG3285	dna ligase
B737_RS22565	COG1793	dna ligase
B737_RS22575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B737_RS22590	COG2267	carboxylic ester hydrolase activity
B737_RS22605	COG3903	Transcriptional regulator
B737_RS22605	COG3629	intracellular signal transduction
B737_RS22610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B737_RS22620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B737_RS22620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B737_RS22620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B737_RS22635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B737_RS22655	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS22660	COG1609	Transcriptional regulator
B737_RS22675	COG0395	ABC-type sugar transport system, permease component
B737_RS22685	COG1609	Transcriptional regulator
B737_RS22705	COG1278	Cold shock
B737_RS22710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B737_RS22760	COG0387	Pfam Sodium calcium exchanger
B737_RS22765	COG0583	DNA-binding transcription factor activity
B737_RS22770	COG0028	Belongs to the TPP enzyme family
B737_RS22815	COG1609	Transcriptional regulator
B737_RS22820	COG1129	ABC transporter
B737_RS22825	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS22830	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS22840	COG3254	rhamnose metabolic process
B737_RS22850	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS22850	COG3347	Dehydrogenase
B737_RS22860	COG1070	Carbohydrate kinase
B737_RS22865	COG2197	response regulator
B737_RS22870	COG4585	Histidine kinase
B737_RS22885	COG3250	beta-galactosidase activity
B737_RS22940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B737_RS22945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS22960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B737_RS22975	COG0045	succinate-CoA ligase (ADP-forming) activity
B737_RS22985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS22995	COG2223	nitrite transmembrane transporter activity
B737_RS23000	COG1802	Transcriptional regulator
B737_RS23005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B737_RS23010	COG3383	formate dehydrogenase (NAD+) activity
B737_RS23015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B737_RS23020	COG1034	ATP synthesis coupled electron transport
B737_RS23025	COG3622	Belongs to the hyi family
B737_RS23030	COG2084	Dehydrogenase
B737_RS23035	COG3960	tartronate-semialdehyde synthase activity
B737_RS23050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B737_RS23055	COG0590	tRNA wobble adenosine to inosine editing
B737_RS23060	COG2252	PERMEase
B737_RS23070	COG1929	Belongs to the glycerate kinase type-1 family
B737_RS23125	COG2066	Belongs to the glutaminase family
B737_RS23140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B737_RS23155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B737_RS23160	COG0596	Alpha beta hydrolase
B737_RS23170	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS23185	COG1793	dna ligase
B737_RS23185	COG3285	dna ligase
B737_RS23190	COG0183	Belongs to the thiolase family
B737_RS23235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS23240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS23245	COG1609	Transcriptional regulator
B737_RS23260	COG2267	carboxylic ester hydrolase activity
B737_RS23295	COG0667	Aldo Keto reductase
B737_RS23300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS23305	COG1968	undecaprenyl-diphosphatase activity
B737_RS23315	COG0339	signal peptide processing
B737_RS23320	COG0740	serine-type endopeptidase activity
B737_RS23325	COG0039	L-malate dehydrogenase activity
B737_RS23360	COG3537	Alpha-1,2-mannosidase
B737_RS23400	COG0747	negative chemotaxis
B737_RS23405	COG0601	transmembrane transport
B737_RS23410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS23415	COG4172	Belongs to the ABC transporter superfamily
B737_RS23435	COG1619	proteins homologs of microcin C7 resistance protein MccF
B737_RS23440	COG0823	Involved in the tonB-independent uptake of proteins
B737_RS23440	COG1506	peptidase
B737_RS23440	COG4946	Tricorn protease homolog
B737_RS23500	COG0477	Major facilitator Superfamily
B737_RS23520	COG0640	Transcriptional regulator
B737_RS23565	COG4941	Belongs to the sigma-70 factor family
B737_RS23630	COG4941	Belongs to the sigma-70 factor family
B737_RS23640	COG2124	cytochrome p450
B737_RS23660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B737_RS23675	COG1309	transcriptional regulator
B737_RS23685	COG1960	acyl-CoA dehydrogenase activity
B737_RS23690	COG1309	transcriptional regulator
B737_RS23705	COG1396	sequence-specific DNA binding
B737_RS23720	COG0640	Transcriptional regulator
B737_RS23730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B737_RS23755	COG1435	thymidine kinase activity
B737_RS23765	COG0494	nUDIX hydrolase
B737_RS23775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS23780	COG0463	Glycosyl transferase, family 2
B737_RS23790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B737_RS23810	COG4977	sequence-specific DNA binding
B737_RS23815	COG1733	regulation of RNA biosynthetic process
B737_RS23835	COG3903	Transcriptional regulator
B737_RS23835	COG3629	intracellular signal transduction
B737_RS23870	COG4865	methylaspartate mutase activity
B737_RS23875	COG0017	Asparaginyl-tRNA synthetase
B737_RS23880	COG0069	glutamate synthase activity
B737_RS23895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B737_RS23945	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS23970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS23995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS24055	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS24060	COG2186	Transcriptional regulator
B737_RS24065	COG0395	ABC-type sugar transport system, permease component
B737_RS24070	COG1175	transmembrane transport
B737_RS24075	COG3293	Transposase
B737_RS24095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B737_RS24105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B737_RS24110	COG4865	methylaspartate mutase activity
B737_RS24120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS24165	COG0789	Transcriptional regulator
B737_RS24215	COG2124	cytochrome p450
B737_RS24250	COG2197	response regulator
B737_RS24255	COG2197	response regulator
B737_RS24265	COG0823	Involved in the tonB-independent uptake of proteins
B737_RS24370	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS24375	COG1414	Transcriptional regulator
B737_RS24380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS24390	COG3485	protocatechuate 3,4-dioxygenase
B737_RS24410	COG3979	chitinase
B737_RS24420	COG1136	(ABC) transporter
B737_RS24425	COG1136	(ABC) transporter
B737_RS24440	COG4221	oxidoreductase activity
B737_RS24445	COG0583	DNA-binding transcription factor activity
B737_RS24455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B737_RS24495	COG4552	Acetyltransferase involved in intracellular survival and related
B737_RS24500	COG4552	Acetyltransferase involved in intracellular survival and related
B737_RS24520	COG1597	lipid kinase activity
B737_RS24530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B737_RS24540	COG2378	regulation of single-species biofilm formation
B737_RS24550	COG1733	regulation of RNA biosynthetic process
B737_RS24560	COG4221	oxidoreductase activity
B737_RS24570	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B737_RS24585	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B737_RS24590	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B737_RS24625	COG0640	Transcriptional regulator
B737_RS24640	COG0697	spore germination
B737_RS24645	COG1222	aaa ATPase
B737_RS24670	COG0517	IMP dehydrogenase activity
B737_RS24670	COG1994	Peptidase M50
B737_RS24685	COG1192	Involved in chromosome partitioning
B737_RS24690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B737_RS24695	COG0140	phosphoribosyl-ATP diphosphatase activity
B737_RS24710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B737_RS24715	COG0646	methionine synthase
B737_RS24715	COG1410	methionine synthase
B737_RS24735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B737_RS24750	COG2814	Major facilitator Superfamily
B737_RS24765	COG0488	(ABC) transporter
B737_RS24770	COG0215	cysteine-tRNA ligase activity
B737_RS24780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B737_RS24790	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
B737_RS24805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B737_RS24820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B737_RS24830	COG0477	Major facilitator Superfamily
B737_RS24835	COG0745	RESPONSE REGULATOR receiver
B737_RS24840	COG2205	protein histidine kinase activity
B737_RS24855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B737_RS24865	COG2304	oxidoreductase activity
B737_RS24875	COG0714	Associated with various cellular activities
B737_RS24880	COG0746	molybdenum cofactor guanylyltransferase activity
B737_RS24885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B737_RS24890	COG3883	PFAM NLP P60 protein
B737_RS24890	COG0791	NLP P60 protein
B737_RS24895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B737_RS24900	COG1285	pathogenesis
B737_RS24910	COG1309	transcriptional regulator
B737_RS24925	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B737_RS24935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B737_RS24940	COG3572	ergothioneine biosynthetic process
B737_RS24950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B737_RS24955	COG2267	carboxylic ester hydrolase activity
B737_RS24980	COG1309	transcriptional regulator
B737_RS25020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B737_RS25040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B737_RS25040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B737_RS25060	COG0789	Transcriptional regulator
B737_RS25075	COG1716	ATPase activity
B737_RS25105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS25110	COG1024	Enoyl-CoA hydratase
B737_RS25120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B737_RS25120	COG1648	precorrin-2 dehydrogenase activity
B737_RS25135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B737_RS25140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B737_RS25145	COG0254	rRNA binding
B737_RS25165	COG2814	Major facilitator Superfamily
B737_RS25185	COG2211	Major facilitator Superfamily
B737_RS25190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS25225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS25235	COG1116	anion transmembrane transporter activity
B737_RS25240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS25245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS25250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B737_RS25275	COG1132	(ABC) transporter
B737_RS25290	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B737_RS25300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B737_RS25305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B737_RS25310	COG1120	ATPase activity
B737_RS25320	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B737_RS25350	COG0395	ABC-type sugar transport system, permease component
B737_RS25355	COG0488	(ABC) transporter
B737_RS25400	COG3293	Transposase
B737_RS25470	COG3250	beta-galactosidase activity
B737_RS25490	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS25500	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS25505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS25515	COG1116	anion transmembrane transporter activity
B737_RS25520	COG2205	protein histidine kinase activity
B737_RS25525	COG0745	RESPONSE REGULATOR receiver
B737_RS25555	COG1846	Transcriptional regulator
B737_RS25570	COG0028	Belongs to the TPP enzyme family
B737_RS25575	COG1073	alpha beta
B737_RS25580	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS25585	COG0179	Fumarylacetoacetate (FAA) hydrolase
B737_RS25595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS25615	COG1129	ABC transporter
B737_RS25620	COG1172	Belongs to the binding-protein-dependent transport system permease family
B737_RS25640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B737_RS25665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B737_RS25670	COG0463	Glycosyl transferase, family 2
B737_RS25680	COG3250	beta-galactosidase activity
B737_RS25705	COG4221	oxidoreductase activity
B737_RS25730	COG0709	Synthesizes selenophosphate from selenide and ATP
B737_RS25760	COG2367	Beta-lactamase
B737_RS25765	COG2249	NAD(P)H dehydrogenase (quinone) activity
B737_RS25780	COG2267	carboxylic ester hydrolase activity
B737_RS25815	COG0596	Alpha beta hydrolase
B737_RS25820	COG1309	transcriptional regulator
B737_RS25875	COG2409	Drug exporters of the RND superfamily
B737_RS25895	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B737_RS25900	COG0019	diaminopimelate decarboxylase activity
B737_RS25950	COG2201	protein-glutamate methylesterase activity
B737_RS25955	COG4585	Histidine kinase
B737_RS25965	COG2197	response regulator
B737_RS25980	COG1324	tolerance protein
B737_RS26035	COG2814	Major facilitator Superfamily
B737_RS26070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B737_RS26075	COG0667	Aldo Keto reductase
B737_RS26100	COG5297	Belongs to the glycosyl hydrolase family 6
B737_RS26105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B737_RS26110	COG5297	Belongs to the glycosyl hydrolase family 6
B737_RS26110	COG4733	cellulase activity
B737_RS26130	COG0395	ABC-type sugar transport system, permease component
B737_RS26140	COG0129	dihydroxy-acid dehydratase activity
B737_RS26155	COG1573	uracil-dna glycosylase
B737_RS26160	COG3285	dna ligase
B737_RS26160	COG1793	dna ligase
B737_RS26170	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B737_RS26270	COG0583	DNA-binding transcription factor activity
B737_RS26275	COG0019	diaminopimelate decarboxylase activity
B737_RS26300	COG0477	Major facilitator Superfamily
B737_RS26305	COG0456	acetyltransferase
B737_RS26315	COG4104	PAAR repeat-containing protein
B737_RS26315	COG3209	COG3209 Rhs family protein
B737_RS26395	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS26425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B737_RS26455	COG0456	acetyltransferase
B737_RS26460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B737_RS26475	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B737_RS26495	COG2018	Roadblock/LC7 domain
B737_RS26500	COG2205	protein histidine kinase activity
B737_RS26535	COG3903	Transcriptional regulator
B737_RS26535	COG3629	intracellular signal transduction
B737_RS26560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS26580	COG1024	Enoyl-CoA hydratase
B737_RS26580	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS26610	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS26615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B737_RS26620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B737_RS26625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B737_RS26630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B737_RS26635	COG1862	Preprotein translocase
B737_RS26640	COG2255	four-way junction helicase activity
B737_RS26645	COG0632	four-way junction helicase activity
B737_RS26650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B737_RS26665	COG0217	transcriptional regulatory protein
B737_RS26670	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B737_RS26685	COG1396	sequence-specific DNA binding
B737_RS26690	COG0644	oxidoreductase
B737_RS26695	COG1960	acyl-CoA dehydrogenase activity
B737_RS26715	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B737_RS26725	COG0277	FAD linked oxidase domain protein
B737_RS26735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B737_RS26735	COG3608	succinylglutamate desuccinylase aspartoacylase
B737_RS26755	COG0438	transferase activity, transferring glycosyl groups
B737_RS26780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B737_RS26785	COG0778	Nitroreductase
B737_RS26825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS26830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B737_RS26835	COG0701	Predicted permease
B737_RS26855	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS26865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS26880	COG1473	amidohydrolase
B737_RS26895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B737_RS26910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS26920	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS26960	COG1597	lipid kinase activity
B737_RS26995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B737_RS27000	COG0395	ABC-type sugar transport system, permease component
B737_RS27005	COG1175	transmembrane transport
B737_RS27020	COG2072	flavoprotein involved in K transport
B737_RS27035	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS27090	COG2211	Major facilitator Superfamily
B737_RS27095	COG1802	Transcriptional regulator
B737_RS27135	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B737_RS27175	COG3483	tryptophan 2,3-dioxygenase activity
B737_RS27190	COG2197	response regulator
B737_RS27195	COG4585	Histidine kinase
B737_RS27205	COG1131	(ABC) transporter
B737_RS27215	COG3510	cephalosporin hydroxylase
B737_RS27220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS27230	COG1819	glycosyl
B737_RS27240	COG1819	glycosyl
B737_RS27280	COG3629	intracellular signal transduction
B737_RS27285	COG1819	glycosyl
B737_RS27290	COG0574	Belongs to the PEP-utilizing enzyme family
B737_RS27290	COG3848	Pyruvate phosphate dikinase
B737_RS27305	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS27325	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS27335	COG2867	negative regulation of translational initiation
B737_RS27340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B737_RS27345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B737_RS27350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B737_RS27355	COG0662	Cupin 2, conserved barrel domain protein
B737_RS27370	COG3104	oligopeptide transport
B737_RS27375	COG2345	Transcriptional regulator
B737_RS27380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS27400	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS27475	COG0659	secondary active sulfate transmembrane transporter activity
B737_RS27485	COG0589	response to stress
B737_RS27505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B737_RS27520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B737_RS27545	COG1271	oxidase subunit
B737_RS27550	COG1294	oxidase, subunit
B737_RS27555	COG4988	ABC transporter
B737_RS27560	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B737_RS27570	COG0517	IMP dehydrogenase activity
B737_RS27570	COG0617	tRNA 3'-terminal CCA addition
B737_RS27570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B737_RS27605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS27625	COG4585	Histidine kinase
B737_RS27630	COG2197	response regulator
B737_RS27650	COG4585	Histidine kinase
B737_RS27655	COG2197	response regulator
B737_RS27710	COG2197	response regulator
B737_RS27750	COG0681	Belongs to the peptidase S26 family
B737_RS27755	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS27815	COG0405	Gamma-glutamyltransferase
B737_RS27820	COG3706	GGDEF domain
B737_RS27865	COG1216	Glycosyl transferase, family 2
B737_RS27870	COG1215	transferase activity, transferring glycosyl groups
B737_RS27880	COG1132	(ABC) transporter
B737_RS27895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS27900	COG0596	Alpha beta hydrolase
B737_RS27955	COG2814	Major facilitator Superfamily
B737_RS27970	COG3903	Transcriptional regulator
B737_RS27970	COG3629	intracellular signal transduction
B737_RS28045	COG0330	HflC and HflK could
B737_RS28120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B737_RS28180	COG0297	glycogen (starch) synthase activity
B737_RS28185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS28215	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS28220	COG1309	transcriptional regulator
B737_RS28225	COG4941	Belongs to the sigma-70 factor family
B737_RS28230	COG4941	Belongs to the sigma-70 factor family
B737_RS28255	COG0583	DNA-binding transcription factor activity
B737_RS28290	COG0515	serine threonine protein kinase
B737_RS28295	COG1595	DNA-templated transcription, initiation
B737_RS28300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS28355	COG0596	Alpha beta hydrolase
B737_RS28360	COG0596	Alpha beta hydrolase
B737_RS28370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B737_RS28385	COG1672	PFAM Archaeal ATPase
B737_RS28385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B737_RS28390	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS28415	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS28445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B737_RS28505	COG2205	protein histidine kinase activity
B737_RS28510	COG0745	RESPONSE REGULATOR receiver
B737_RS28515	COG1216	Glycosyl transferase, family 2
B737_RS28520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B737_RS28545	COG1609	Transcriptional regulator
B737_RS28555	COG1309	transcriptional regulator
B737_RS28610	COG4941	Belongs to the sigma-70 factor family
B737_RS28630	COG1335	isochorismatase
B737_RS28660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS28665	COG1309	transcriptional regulator
B737_RS28680	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B737_RS28685	COG1414	Transcriptional regulator
B737_RS28690	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS28710	COG1278	Cold shock
B737_RS28730	COG0300	oxidoreductase activity
B737_RS28740	COG3795	YCII-related domain
B737_RS28755	COG3263	regulation of cellular component size
B737_RS28765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B737_RS28775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B737_RS28815	COG0745	RESPONSE REGULATOR receiver
B737_RS28820	COG5000	phosphorelay sensor kinase activity
B737_RS28820	COG5002	protein histidine kinase activity
B737_RS28845	COG1846	Transcriptional regulator
B737_RS28850	COG0038	chloride channel
B737_RS28880	COG3383	formate dehydrogenase (NAD+) activity
B737_RS28880	COG0243	molybdopterin cofactor binding
B737_RS28885	COG3383	formate dehydrogenase (NAD+) activity
B737_RS28885	COG0243	molybdopterin cofactor binding
B737_RS28890	COG0437	4 iron, 4 sulfur cluster binding
B737_RS28925	COG2116	formate transmembrane transporter activity
B737_RS28950	COG0531	amino acid
B737_RS28955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS28975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B737_RS28980	COG2080	2 iron, 2 sulfur cluster binding
B737_RS28990	COG0667	Aldo Keto reductase
B737_RS29035	COG3250	beta-galactosidase activity
B737_RS29040	COG0395	ABC-type sugar transport system, permease component
B737_RS29045	COG1175	transmembrane transport
B737_RS29050	COG1609	Transcriptional regulator
B737_RS29055	COG1609	Transcriptional regulator
B737_RS29075	COG1609	Transcriptional regulator
B737_RS29095	COG2207	Transcriptional regulator
B737_RS29095	COG1917	Cupin 2, conserved barrel domain protein
B737_RS29105	COG3250	beta-galactosidase activity
B737_RS29235	COG3293	Transposase
B737_RS29265	COG1857	crispr-associated protein
B737_RS29375	COG5297	Belongs to the glycosyl hydrolase family 6
B737_RS29375	COG4733	cellulase activity
B737_RS29400	COG0154	amidase activity
B737_RS29405	COG0789	Transcriptional regulator
B737_RS29410	COG0640	Transcriptional regulator
B737_RS29440	COG0673	inositol 2-dehydrogenase activity
B737_RS29465	COG1653	transport
B737_RS29495	COG3842	ATPase activity
B737_RS29505	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B737_RS29510	COG0028	Belongs to the TPP enzyme family
B737_RS29530	COG2197	response regulator
B737_RS29540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B737_RS29550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B737_RS29560	COG0702	epimerase
B737_RS29570	COG0583	DNA-binding transcription factor activity
B737_RS29580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B737_RS29640	COG0300	oxidoreductase activity
B737_RS29645	COG4221	oxidoreductase activity
B737_RS29650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B737_RS29710	COG2318	DinB family
B737_RS29715	COG0667	Aldo Keto reductase
B737_RS29730	COG2267	carboxylic ester hydrolase activity
B737_RS29740	COG3903	Transcriptional regulator
B737_RS29740	COG3629	intracellular signal transduction
B737_RS29800	COG4974	Belongs to the 'phage' integrase family
B737_RS29805	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS29855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B737_RS29895	COG2815	serine threonine protein kinase
B737_RS29895	COG0515	serine threonine protein kinase
B737_RS29910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B737_RS29940	COG3511	phospholipase C
B737_RS29990	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS30040	COG0714	Associated with various cellular activities
B737_RS30050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B737_RS30055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B737_RS30065	COG1733	regulation of RNA biosynthetic process
B737_RS30075	COG5492	domain, Protein
B737_RS30090	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS30095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B737_RS30105	COG1414	Transcriptional regulator
B737_RS30110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B737_RS30210	COG1160	GTP binding
B737_RS30240	COG0475	glutathione-regulated potassium exporter activity
B737_RS30245	COG2936	dipeptidyl-peptidase activity
B737_RS30250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS30260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B737_RS30290	COG0494	nUDIX hydrolase
B737_RS30295	COG0504	CTP synthase activity
B737_RS30305	COG1802	Transcriptional regulator
B737_RS30310	COG1953	Uracil, thiamine, allantoin
B737_RS30345	COG1063	alcohol dehydrogenase
B737_RS30360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B737_RS30375	COG0647	UMP catabolic process
B737_RS30400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B737_RS30405	COG2094	Belongs to the DNA glycosylase MPG family
B737_RS30425	COG0165	Argininosuccinate lyase
B737_RS30430	COG0137	argininosuccinate synthase activity
B737_RS30435	COG1438	arginine binding
B737_RS30440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B737_RS30445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B737_RS30450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B737_RS30455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B737_RS30460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B737_RS30475	COG0596	Alpha beta hydrolase
B737_RS30485	COG0072	phenylalanine-tRNA ligase activity
B737_RS30485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B737_RS30490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B737_RS30500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B737_RS30505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B737_RS30510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B737_RS30555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B737_RS30560	COG2610	gluconate transmembrane transporter activity
B737_RS30565	COG2706	6-phosphogluconolactonase activity
B737_RS30575	COG1175	transmembrane transport
B737_RS30580	COG0395	ABC-type sugar transport system, permease component
B737_RS30595	COG4565	transcriptional regulatory protein
B737_RS30600	COG3290	protein histidine kinase activity
B737_RS30605	COG1301	dicarboxylic acid transport
B737_RS30655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS30680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B737_RS30685	COG0328	RNA-DNA hybrid ribonuclease activity
B737_RS30690	COG3012	SEC-C Motif Domain Protein
B737_RS30700	COG3250	beta-galactosidase activity
B737_RS30705	COG2272	Belongs to the type-B carboxylesterase lipase family
B737_RS30720	COG0406	alpha-ribazole phosphatase activity
B737_RS30740	COG1609	Transcriptional regulator
B737_RS30760	COG1506	peptidase
B737_RS30760	COG4946	Tricorn protease homolog
B737_RS30760	COG0823	Involved in the tonB-independent uptake of proteins
B737_RS30770	COG1131	(ABC) transporter
B737_RS30790	COG1024	Enoyl-CoA hydratase
B737_RS30830	COG0237	dephospho-CoA kinase activity
B737_RS30830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B737_RS30855	COG0539	negative regulation of cytoplasmic translation
B737_RS30860	COG2226	methyltransferase
B737_RS30880	COG1511	domain protein
B737_RS30885	COG1309	transcriptional regulator
B737_RS30890	COG2207	Transcriptional regulator
B737_RS30895	COG0604	alcohol dehydrogenase
B737_RS30920	COG0583	DNA-binding transcription factor activity
B737_RS31185	COG4585	Histidine kinase
B737_RS31190	COG2197	response regulator
B737_RS31210	COG2197	response regulator
B737_RS31215	COG4585	Histidine kinase
B737_RS31235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B737_RS31240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B737_RS31260	COG1454	alcohol dehydrogenase
B737_RS31270	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS31290	COG0596	Alpha beta hydrolase
B737_RS31310	COG4977	sequence-specific DNA binding
B737_RS31315	COG0596	Alpha beta hydrolase
B737_RS31325	COG0300	oxidoreductase activity
B737_RS31365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B737_RS31410	COG3251	PFAM MbtH domain protein
B737_RS31465	COG2814	Major facilitator Superfamily
B737_RS31470	COG0702	epimerase
B737_RS31480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B737_RS31485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B737_RS31495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B737_RS31500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B737_RS31515	COG0768	penicillin binding
B737_RS31525	COG0275	rRNA processing
B737_RS31530	COG2001	Belongs to the MraZ family
B737_RS31560	COG0714	Associated with various cellular activities
B737_RS31570	COG1305	Transglutaminase-like
B737_RS31580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B737_RS31590	COG1192	Involved in chromosome partitioning
B737_RS31595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B737_RS31600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B737_RS31610	COG0167	dihydroorotate dehydrogenase activity
B737_RS31625	COG1842	Phage shock protein A
B737_RS31630	COG1396	sequence-specific DNA binding
B737_RS31635	COG1546	Belongs to the CinA family
B737_RS31635	COG1058	Belongs to the CinA family
B737_RS31645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B737_RS31650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B737_RS31680	COG1674	ftsk spoiiie
B737_RS31690	COG0655	NAD(P)H dehydrogenase (quinone) activity
B737_RS31710	COG1113	amino acid transport
B737_RS31720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B737_RS31725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B737_RS31730	COG0515	serine threonine protein kinase
B737_RS31765	COG3214	Protein conserved in bacteria
B737_RS31805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B737_RS31815	COG1185	polyribonucleotide nucleotidyltransferase activity
B737_RS31820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B737_RS31840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B737_RS31865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B737_RS31875	COG2268	Band 7 protein
B737_RS31890	COG2226	methyltransferase
B737_RS31925	COG0195	Participates in both transcription termination and antitermination
B737_RS31930	COG0779	Required for maturation of 30S ribosomal subunits
B737_RS31960	COG3226	Transcriptional regulator
B737_RS31970	COG4585	Histidine kinase
B737_RS31975	COG2197	response regulator
B737_RS31985	COG1733	regulation of RNA biosynthetic process
B737_RS31995	COG1309	transcriptional regulator
B737_RS32000	COG2936	dipeptidyl-peptidase activity
B737_RS32015	COG0745	RESPONSE REGULATOR receiver
B737_RS32020	COG5002	protein histidine kinase activity
B737_RS32030	COG3629	intracellular signal transduction
B737_RS32030	COG3903	Transcriptional regulator
B737_RS32050	COG0583	DNA-binding transcription factor activity
B737_RS32060	COG1024	Enoyl-CoA hydratase
B737_RS32070	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS32075	COG1960	acyl-CoA dehydrogenase activity
B737_RS32080	COG1316	TRANSCRIPTIONal
B737_RS32110	COG0583	DNA-binding transcription factor activity
B737_RS32135	COG2124	cytochrome p450
B737_RS32150	COG0702	epimerase
B737_RS32175	COG3903	Transcriptional regulator
B737_RS32175	COG3629	intracellular signal transduction
B737_RS32225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B737_RS32265	COG1595	DNA-templated transcription, initiation
B737_RS32290	COG3507	Belongs to the glycosyl hydrolase 43 family
B737_RS32305	COG4941	Belongs to the sigma-70 factor family
B737_RS32310	COG3795	YCII-related domain
B737_RS32315	COG0596	Alpha beta hydrolase
B737_RS32320	COG1309	transcriptional regulator
B737_RS32325	COG0604	alcohol dehydrogenase
B737_RS32350	COG0443	Heat shock 70 kDa protein
B737_RS32365	COG1228	amidohydrolase
B737_RS32405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B737_RS32435	COG2197	response regulator
B737_RS32465	COG2755	lipolytic protein G-D-S-L family
B737_RS32465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B737_RS32515	COG3629	intracellular signal transduction
B737_RS32515	COG3903	Transcriptional regulator
B737_RS32540	COG0667	Aldo Keto reductase
B737_RS32570	COG1960	acyl-CoA dehydrogenase activity
B737_RS32585	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS32600	COG0596	Alpha beta hydrolase
B737_RS32605	COG2197	response regulator
B737_RS32630	COG0477	Major facilitator Superfamily
B737_RS32680	COG4585	Histidine kinase
B737_RS32685	COG2197	response regulator
B737_RS32700	COG0586	Pfam SNARE associated Golgi protein
B737_RS32710	COG1968	undecaprenyl-diphosphatase activity
B737_RS32750	COG4585	Histidine kinase
B737_RS32755	COG2197	response regulator
B737_RS32765	COG2201	protein-glutamate methylesterase activity
B737_RS32780	COG1309	transcriptional regulator
B737_RS32785	COG0702	epimerase
B737_RS32790	COG0702	epimerase
B737_RS32805	COG0657	acetylesterase activity
B737_RS32815	COG2814	Major facilitator Superfamily
B737_RS32840	COG4977	sequence-specific DNA binding
B737_RS32895	COG1120	ATPase activity
B737_RS32900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B737_RS33015	COG0243	molybdopterin cofactor binding
B737_RS33065	COG0028	Belongs to the TPP enzyme family
B737_RS33070	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS33075	COG0247	lactate metabolic process
B737_RS33075	COG0277	FAD linked oxidase domain protein
B737_RS33100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B737_RS33105	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B737_RS33115	COG1659	Linocin_M18 bacteriocin protein
B737_RS33135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B737_RS33155	COG4106	trans-aconitate 2-methyltransferase activity
B737_RS33170	COG1595	DNA-templated transcription, initiation
B737_RS33185	COG0477	Major facilitator Superfamily
B737_RS33205	COG2318	DinB family
B737_RS33220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B737_RS33230	COG2197	response regulator
B737_RS33235	COG4585	Histidine kinase
B737_RS33245	COG1131	(ABC) transporter
B737_RS33250	COG0423	glycine-tRNA ligase activity
B737_RS33290	COG0701	Predicted permease
B737_RS33300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B737_RS33305	COG1381	Involved in DNA repair and RecF pathway recombination
B737_RS33335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B737_RS33350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B737_RS33360	COG0537	adenosine 5'-monophosphoramidase activity
B737_RS33370	COG0484	heat shock protein binding
B737_RS33400	COG0667	Aldo Keto reductase
B737_RS33435	COG2205	protein histidine kinase activity
B737_RS33440	COG0745	RESPONSE REGULATOR receiver
B737_RS33445	COG1953	Uracil, thiamine, allantoin
B737_RS33455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B737_RS33545	COG0326	Molecular chaperone. Has ATPase activity
B737_RS33560	COG1024	Enoyl-CoA hydratase
B737_RS33565	COG2732	(Barnase) inhibitor
B737_RS33570	COG4290	ribonuclease
B737_RS33580	COG0604	alcohol dehydrogenase
B737_RS33590	COG0531	amino acid
B737_RS33595	COG2070	2-Nitropropane dioxygenase
B737_RS33655	COG0268	Binds directly to 16S ribosomal RNA
B737_RS33665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B737_RS33675	COG2333	competence protein COMEC
B737_RS33675	COG0658	competence protein
B737_RS33685	COG1307	EDD domain protein, DegV family
B737_RS33695	COG0406	alpha-ribazole phosphatase activity
B737_RS33700	COG0799	negative regulation of ribosome biogenesis
B737_RS33705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B737_RS33720	COG0018	arginyl-trna synthetase
B737_RS33740	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS33750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B737_RS33755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B737_RS33760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B737_RS33765	COG1530	ribonuclease E activity
B737_RS33765	COG1530	ribonuclease E activity
B737_RS33785	COG1131	(ABC) transporter
B737_RS33800	COG0105	UTP biosynthetic process
B737_RS33810	COG2366	antibiotic biosynthetic process
B737_RS33820	COG0285	dihydrofolate synthase activity
B737_RS33845	COG0583	DNA-binding transcription factor activity
B737_RS33850	COG0525	valine-tRNA ligase activity
B737_RS33860	COG1846	Transcriptional regulator
B737_RS33865	COG0477	Major facilitator Superfamily
B737_RS33880	COG1316	TRANSCRIPTIONal
B737_RS33890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B737_RS33920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B737_RS33925	COG0740	serine-type endopeptidase activity
B737_RS33930	COG0740	serine-type endopeptidase activity
B737_RS33935	COG0544	peptidyl-prolyl cis-trans isomerase activity
B737_RS33945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B737_RS33955	COG2205	protein histidine kinase activity
B737_RS33960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B737_RS34015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B737_RS34060	COG3629	intracellular signal transduction
B737_RS34060	COG3903	Transcriptional regulator
B737_RS34070	COG3537	Alpha-1,2-mannosidase
B737_RS34075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B737_RS34080	COG3559	Exporter of polyketide antibiotics
B737_RS34085	COG1131	(ABC) transporter
B737_RS34090	COG1309	transcriptional regulator
B737_RS34100	COG1940	carbohydrate kinase activity
B737_RS34120	COG2814	Major facilitator Superfamily
B737_RS34155	COG0693	protein deglycase activity
B737_RS34160	COG2208	phosphoserine phosphatase activity
B737_RS34165	COG0784	Response regulator, receiver
B737_RS34165	COG5002	protein histidine kinase activity
B737_RS34185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B737_RS34200	COG1396	sequence-specific DNA binding
B737_RS34220	COG0583	DNA-binding transcription factor activity
B737_RS34230	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS34240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS34255	COG1733	regulation of RNA biosynthetic process
B737_RS34260	COG3345	alpha-galactosidase
B737_RS34285	COG0459	protein refolding
B737_RS34295	COG0698	ribose 5-phosphate isomerase
B737_RS34310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B737_RS34325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B737_RS34345	COG0668	transmembrane transport
B737_RS34355	COG0366	Alpha amylase catalytic
B737_RS34375	COG2902	Dehydrogenase
B737_RS34390	COG3336	cytochrome c oxidase
B737_RS34405	COG0738	Major facilitator superfamily
B737_RS34425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B737_RS34430	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B737_RS34450	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B737_RS34490	COG0477	Major facilitator Superfamily
B737_RS34495	COG0596	Alpha beta hydrolase
B737_RS34515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B737_RS34535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B737_RS34580	COG2124	cytochrome p450
B737_RS34615	COG1733	regulation of RNA biosynthetic process
B737_RS34620	COG4941	Belongs to the sigma-70 factor family
B737_RS34625	COG3795	YCII-related domain
B737_RS34635	COG0009	L-threonylcarbamoyladenylate synthase
B737_RS34650	COG2197	response regulator
B737_RS34655	COG4977	sequence-specific DNA binding
B737_RS34655	COG1917	Cupin 2, conserved barrel domain protein
B737_RS34660	COG2197	response regulator
B737_RS34665	COG4585	Histidine kinase
B737_RS34710	COG1937	Protein conserved in bacteria
B737_RS34750	COG4221	oxidoreductase activity
B737_RS34765	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B737_RS34790	COG0657	acetylesterase activity
B737_RS34810	COG0745	RESPONSE REGULATOR receiver
B737_RS34815	COG2205	protein histidine kinase activity
B737_RS34825	COG1609	Transcriptional regulator
B737_RS34845	COG0366	Alpha amylase catalytic
B737_RS34860	COG0367	asparagine synthase
B737_RS34865	COG1940	carbohydrate kinase activity
B737_RS34885	COG0583	DNA-binding transcription factor activity
B737_RS34925	COG1609	Transcriptional regulator
B737_RS34960	COG0531	amino acid
B737_RS34965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B737_RS34995	COG3835	regulator
B737_RS35020	COG1021	2,3-dihydroxybenzoate-AMP ligase
B737_RS35040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B737_RS35045	COG0583	DNA-binding transcription factor activity
B737_RS35090	COG1024	Enoyl-CoA hydratase
B737_RS35150	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS35165	COG1643	Atp-dependent helicase
B737_RS35180	COG3268	Saccharopine dehydrogenase
B737_RS35185	COG2072	flavoprotein involved in K transport
B737_RS35200	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B737_RS35200	COG1796	DNA polymerase
B737_RS35210	COG1802	Transcriptional regulator
B737_RS35235	COG3706	GGDEF domain
B737_RS35245	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
B737_RS35265	COG4941	Belongs to the sigma-70 factor family
B737_RS35285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B737_RS35300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS35310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B737_RS35315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS35320	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B737_RS35320	COG0235	Class ii aldolase
B737_RS35340	COG1695	Transcriptional regulator
B737_RS35350	COG3959	Transketolase, thiamine diphosphate binding domain
B737_RS35355	COG1309	transcriptional regulator
B737_RS35360	COG0247	lactate metabolic process
B737_RS35360	COG0277	FAD linked oxidase domain protein
B737_RS35370	COG2197	response regulator
B737_RS35390	COG0559	Belongs to the binding-protein-dependent transport system permease family
B737_RS35395	COG0559	Belongs to the binding-protein-dependent transport system permease family
B737_RS35410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B737_RS35415	COG3537	Alpha-1,2-mannosidase
B737_RS35420	COG1739	Uncharacterized protein family UPF0029
B737_RS35425	COG0070	glutamate synthase
B737_RS35425	COG0067	glutamate synthase
B737_RS35425	COG0069	glutamate synthase activity
B737_RS35435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B737_RS35465	COG1492	cobalamin metabolic process
B737_RS35470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B737_RS35480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B737_RS35485	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B737_RS35490	COG2378	regulation of single-species biofilm formation
B737_RS35505	COG1797	cobyrinic acid a,c-diamide synthase activity
B737_RS35540	COG0778	Nitroreductase
B737_RS35570	COG1131	(ABC) transporter
B737_RS35580	COG1476	TRANSCRIPTIONal
B737_RS35595	COG3469	chitinase activity
B737_RS35615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B737_RS35640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS35650	COG0433	COG0433 Predicted ATPase
B737_RS35655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B737_RS35665	COG0477	Major facilitator Superfamily
B737_RS35670	COG1376	ErfK ybiS ycfS ynhG family protein
B737_RS35885	COG1960	acyl-CoA dehydrogenase activity
B737_RS35895	COG0022	dehydrogenase e1 component
B737_RS35900	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS35905	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS35910	COG1024	Enoyl-CoA hydratase
B737_RS35930	COG0477	Major facilitator Superfamily
B737_RS35940	COG2301	Belongs to the HpcH HpaI aldolase family
B737_RS35950	COG2186	Transcriptional regulator
B737_RS35955	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS35960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS35975	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS36010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B737_RS36020	COG1309	transcriptional regulator
B737_RS36030	COG0604	alcohol dehydrogenase
B737_RS36085	COG1960	acyl-CoA dehydrogenase activity
B737_RS36090	COG1960	acyl-CoA dehydrogenase activity
B737_RS36100	COG2186	Transcriptional regulator
B737_RS36115	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS36115	COG0604	alcohol dehydrogenase
B737_RS36115	COG3321	synthase
B737_RS36120	COG1960	acyl-CoA dehydrogenase activity
B737_RS36125	COG1960	acyl-CoA dehydrogenase activity
B737_RS36165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS36180	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS36210	COG1414	Transcriptional regulator
B737_RS36220	COG2267	carboxylic ester hydrolase activity
B737_RS36235	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS36240	COG0259	pyridoxamine-phosphate oxidase activity
B737_RS36245	COG0183	Belongs to the thiolase family
B737_RS36250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS36255	COG1024	Enoyl-CoA hydratase
B737_RS36260	COG1960	acyl-CoA dehydrogenase activity
B737_RS36275	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS36285	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS36295	COG1024	Enoyl-CoA hydratase
B737_RS36305	COG1024	Enoyl-CoA hydratase
B737_RS36325	COG1024	Enoyl-CoA hydratase
B737_RS36335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B737_RS36345	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS36365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B737_RS36400	COG1335	isochorismatase
B737_RS36420	COG1309	transcriptional regulator
B737_RS36430	COG0022	dehydrogenase e1 component
B737_RS36460	COG1063	alcohol dehydrogenase
B737_RS36470	COG4585	Histidine kinase
B737_RS36475	COG2197	response regulator
B737_RS36495	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS36500	COG2271	Major facilitator Superfamily
B737_RS36530	COG0235	Class ii aldolase
B737_RS36535	COG0477	Major facilitator Superfamily
B737_RS36540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B737_RS36570	COG0673	inositol 2-dehydrogenase activity
B737_RS36575	COG2211	Major facilitator Superfamily
B737_RS36580	COG1609	Transcriptional regulator
B737_RS36585	COG1653	transport
B737_RS36595	COG0395	ABC-type sugar transport system, permease component
B737_RS36605	COG0596	Alpha beta hydrolase
B737_RS36615	COG0596	Alpha beta hydrolase
B737_RS36630	COG2084	Dehydrogenase
B737_RS36640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B737_RS36645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B737_RS36655	COG0189	ligase activity
B737_RS36670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS36675	COG0625	glutathione transferase activity
B737_RS36685	COG2271	Major facilitator Superfamily
B737_RS36700	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS36885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B737_RS36930	COG2856	Zn peptidase
B737_RS36965	COG0702	epimerase
B737_RS36980	COG0702	epimerase
B737_RS36990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B737_RS36995	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B737_RS37000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS37005	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS37010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B737_RS37010	COG2169	Transcriptional regulator
B737_RS37080	COG5297	Belongs to the glycosyl hydrolase family 6
B737_RS37080	COG4733	cellulase activity
B737_RS37090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B737_RS37110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B737_RS37145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B737_RS37150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B737_RS37170	COG1960	acyl-CoA dehydrogenase activity
B737_RS37195	COG0154	amidase activity
B737_RS37210	COG0583	DNA-binding transcription factor activity
B737_RS37250	COG1131	(ABC) transporter
B737_RS37260	COG3345	alpha-galactosidase
B737_RS37305	COG0438	transferase activity, transferring glycosyl groups
B737_RS37325	COG0297	glycogen (starch) synthase activity
B737_RS37330	COG0438	transferase activity, transferring glycosyl groups
B737_RS37345	COG0463	Glycosyl transferase, family 2
B737_RS37380	COG3250	beta-galactosidase activity
B737_RS37385	COG3401	FG-GAP repeat protein
B737_RS37405	COG1609	Transcriptional regulator
B737_RS37415	COG0395	ABC-type sugar transport system, permease component
B737_RS37420	COG1175	transmembrane transport
B737_RS37460	COG0596	Alpha beta hydrolase
B737_RS37465	COG2770	Histidine kinase
B737_RS37465	COG2208	phosphoserine phosphatase activity
B737_RS37475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B737_RS37485	COG2226	methyltransferase
B737_RS37495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B737_RS37535	COG0667	Aldo Keto reductase
B737_RS37540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS37560	COG0587	DNA-directed DNA polymerase activity
B737_RS37565	COG4941	Belongs to the sigma-70 factor family
B737_RS37570	COG3795	YCII-related domain
B737_RS37580	COG1982	Orn Lys Arg decarboxylase major
B737_RS37595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B737_RS37605	COG1725	Transcriptional regulator
B737_RS37610	COG1131	(ABC) transporter
B737_RS37630	COG3509	depolymerase
B737_RS37645	COG1528	Iron-storage protein
B737_RS37670	COG2018	Roadblock/LC7 domain
B737_RS37695	COG1764	response to oxidative stress
B737_RS37705	COG2267	carboxylic ester hydrolase activity
B737_RS37720	COG0667	Aldo Keto reductase
B737_RS37725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B737_RS37760	COG0395	ABC-type sugar transport system, permease component
B737_RS37765	COG1175	transmembrane transport
B737_RS37770	COG1609	Transcriptional regulator
B737_RS37795	COG0604	alcohol dehydrogenase
B737_RS37825	COG1595	DNA-templated transcription, initiation
B737_RS37835	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS37840	COG0129	dihydroxy-acid dehydratase activity
B737_RS37845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B737_RS37900	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B737_RS37935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B737_RS37945	COG2226	methyltransferase
B737_RS37950	COG2508	Transcriptional regulator
B737_RS37960	COG3655	Transcriptional regulator
B737_RS38005	COG4981	capsule polysaccharide biosynthetic process
B737_RS38030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS38035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B737_RS38060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS38095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B737_RS38110	COG3226	Transcriptional regulator
B737_RS38115	COG1012	belongs to the aldehyde dehydrogenase family
B737_RS38170	COG0508	dehydrogenase complex catalyzes the overall conversion of
B737_RS38195	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS38210	COG0745	RESPONSE REGULATOR receiver
B737_RS38215	COG5002	protein histidine kinase activity
B737_RS38245	COG0515	serine threonine protein kinase
B737_RS38245	COG2815	serine threonine protein kinase
B737_RS38265	COG0640	Transcriptional regulator
B737_RS38275	COG2837	iron assimilation
B737_RS38280	COG3511	phospholipase C
B737_RS38295	COG0784	Response regulator, receiver
B737_RS38300	COG4251	negative regulation of phosphorylation
B737_RS38305	COG0745	RESPONSE REGULATOR receiver
B737_RS38385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B737_RS38410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B737_RS38485	COG1309	transcriptional regulator
B737_RS38510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B737_RS38515	COG1309	transcriptional regulator
B737_RS38535	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS38540	COG3383	formate dehydrogenase (NAD+) activity
B737_RS38545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS38590	COG2814	Major facilitator Superfamily
B737_RS38625	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS38655	COG0706	membrane insertase activity
B737_RS38665	COG1408	metallophosphoesterase
B737_RS38675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B737_RS38680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B737_RS38705	COG2018	Roadblock/LC7 domain
B737_RS38725	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS38735	COG3706	GGDEF domain
B737_RS38750	COG1316	TRANSCRIPTIONal
B737_RS38790	COG4977	sequence-specific DNA binding
B737_RS38795	COG0667	Aldo Keto reductase
B737_RS38800	COG2207	Transcriptional regulator
B737_RS38830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B737_RS38835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B737_RS38840	COG1234	tRNA 3'-trailer cleavage
B737_RS38845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B737_RS38860	COG1794	racemase activity, acting on amino acids and derivatives
B737_RS38865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B737_RS38890	COG3191	aminopeptidase activity
B737_RS38905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B737_RS38910	COG1335	isochorismatase
B737_RS38915	COG0800	Aldolase
B737_RS38925	COG1268	BioY protein
B737_RS38955	COG0560	Phosphoserine phosphatase
B737_RS38955	COG3830	Belongs to the UPF0237 family
B737_RS38960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B737_RS38970	COG2267	carboxylic ester hydrolase activity
B737_RS38990	COG2801	Transposase and inactivated derivatives
B737_RS39005	COG0626	cystathionine gamma-synthase activity
B737_RS39010	COG1522	sequence-specific DNA binding
B737_RS39020	COG1522	sequence-specific DNA binding
B737_RS39055	COG2376	Dihydroxyacetone kinase
B737_RS39085	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B737_RS39090	COG1051	belongs to the nudix hydrolase family
B737_RS39105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B737_RS39110	COG4977	sequence-specific DNA binding
B737_RS39115	COG1335	isochorismatase
B737_RS39135	COG1280	lysine exporter protein (LysE YggA)
B737_RS39140	COG1280	lysine exporter protein (LysE YggA)
B737_RS39150	COG0702	epimerase
B737_RS39155	COG3631	Ketosteroid isomerase-related protein
B737_RS39160	COG1309	transcriptional regulator
B737_RS39175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B737_RS39185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B737_RS39190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B737_RS39195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B737_RS39200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B737_RS39205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B737_RS39210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B737_RS39215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B737_RS39220	COG0356	it plays a direct role in the translocation of protons across the membrane
B737_RS39230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B737_RS39245	COG2890	protein-(glutamine-N5) methyltransferase activity
B737_RS39250	COG0463	Glycosyl transferase, family 2
B737_RS39270	COG0254	rRNA binding
B737_RS39280	COG0083	homoserine kinase activity
B737_RS39285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B737_RS39290	COG0460	homoserine dehydrogenase
B737_RS39295	COG0019	diaminopimelate decarboxylase activity
B737_RS39300	COG0018	arginyl-trna synthetase
B737_RS39335	COG0596	Alpha beta hydrolase
B737_RS39415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B737_RS39430	COG3903	Transcriptional regulator
B737_RS39430	COG3629	intracellular signal transduction
B737_RS39435	COG2124	cytochrome p450
B737_RS39435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B737_RS39455	COG3345	alpha-galactosidase
B737_RS39475	COG3250	beta-galactosidase activity
B737_RS39480	COG3693	PFAM glycoside hydrolase, family 10
B737_RS39545	COG5433	transposase activity
B737_RS39595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B737_RS39600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B737_RS39620	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS39630	COG0145	ligase activity
B737_RS39655	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
B737_RS39670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B737_RS39685	COG0154	amidase activity
B737_RS39715	COG0473	3-isopropylmalate dehydrogenase activity
B737_RS39725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B737_RS39735	COG0667	Aldo Keto reductase
B737_RS39755	COG0028	Belongs to the TPP enzyme family
B737_RS39780	COG4585	Histidine kinase
B737_RS39785	COG2197	response regulator
B737_RS39790	COG2409	Drug exporters of the RND superfamily
B737_RS39795	COG3537	Alpha-1,2-mannosidase
B737_RS39800	COG1024	Enoyl-CoA hydratase
B737_RS39800	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS39805	COG0183	Belongs to the thiolase family
B737_RS39810	COG1309	transcriptional regulator
B737_RS39845	COG1960	acyl-CoA dehydrogenase activity
B737_RS39850	COG1960	acyl-CoA dehydrogenase activity
B737_RS39910	COG4221	oxidoreductase activity
B737_RS39940	COG1960	acyl-CoA dehydrogenase activity
B737_RS39950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B737_RS39980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B737_RS39995	COG0346	lactoylglutathione lyase activity
B737_RS40015	COG2226	methyltransferase
B737_RS40020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B737_RS40020	COG2508	Transcriptional regulator
B737_RS40035	COG0686	Belongs to the AlaDH PNT family
B737_RS40045	COG2205	protein histidine kinase activity
B737_RS40055	COG0745	RESPONSE REGULATOR receiver
B737_RS40070	COG1132	(ABC) transporter
B737_RS40085	COG0567	Dehydrogenase, E1 component
B737_RS40085	COG0508	dehydrogenase complex catalyzes the overall conversion of
B737_RS40095	COG1216	Glycosyl transferase, family 2
B737_RS40100	COG2223	nitrite transmembrane transporter activity
B737_RS40110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS40125	COG1174	glycine betaine transport
B737_RS40130	COG1174	glycine betaine transport
B737_RS40135	COG1125	glycine betaine transport
B737_RS40135	COG0517	IMP dehydrogenase activity
B737_RS40150	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B737_RS40160	COG1846	Transcriptional regulator
B737_RS40175	COG0406	alpha-ribazole phosphatase activity
B737_RS40190	COG1597	lipid kinase activity
B737_RS40215	COG1595	DNA-templated transcription, initiation
B737_RS40220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B737_RS40230	COG2135	peptidase activity
B737_RS40260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B737_RS40265	COG1011	Hydrolase
B737_RS40280	COG0653	protein targeting
B737_RS40285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B737_RS40295	COG5401	PFAM Sporulation and spore germination
B737_RS40300	COG5000	phosphorelay sensor kinase activity
B737_RS40300	COG5002	protein histidine kinase activity
B737_RS40305	COG0745	RESPONSE REGULATOR receiver
B737_RS40315	COG1414	Transcriptional regulator
B737_RS40385	COG0531	amino acid
B737_RS40395	COG3903	Transcriptional regulator
B737_RS40395	COG3629	intracellular signal transduction
B737_RS40400	COG1482	cell wall glycoprotein biosynthetic process
B737_RS40410	COG2835	tetraacyldisaccharide 4'-kinase activity
B737_RS40415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B737_RS40455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS40470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS40475	COG0601	transmembrane transport
B737_RS40485	COG0747	negative chemotaxis
B737_RS40490	COG1217	gtp-binding protein TYPA
B737_RS40500	COG0180	Tryptophanyl-tRNA synthetase
B737_RS40505	COG0494	nUDIX hydrolase
B737_RS40505	COG0406	alpha-ribazole phosphatase activity
B737_RS40515	COG0745	RESPONSE REGULATOR receiver
B737_RS40525	COG1131	(ABC) transporter
B737_RS40535	COG3842	ATPase activity
B737_RS40540	COG4149	molybdate abc transporter
B737_RS40550	COG2154	pterin-4-alpha-carbinolamine dehydratase
B737_RS40570	COG0012	GTP binding
B737_RS40585	COG0419	ATPase involved in DNA repair
B737_RS40590	COG0420	3'-5' exonuclease activity
B737_RS40605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B737_RS40615	COG1570	exodeoxyribonuclease VII activity
B737_RS40625	COG1722	exodeoxyribonuclease VII activity
B737_RS40640	COG0492	ferredoxin-NADP+ reductase activity
B737_RS40645	COG0114	fumarate hydratase activity
B737_RS40655	COG1793	dna ligase
B737_RS40670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS40695	COG1228	amidohydrolase
B737_RS40700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B737_RS40725	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B737_RS40755	COG1331	Highly conserved protein containing a thioredoxin domain
B737_RS40770	COG2890	protein-(glutamine-N5) methyltransferase activity
B737_RS40775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B737_RS40785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B737_RS40795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B737_RS40800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS40810	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B737_RS40840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B737_RS40875	COG0183	Belongs to the thiolase family
B737_RS40950	COG3903	Transcriptional regulator
B737_RS40950	COG3629	intracellular signal transduction
B737_RS40955	COG2723	6-phospho-beta-galactosidase activity
B737_RS40965	COG1175	transmembrane transport
B737_RS40980	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS40985	COG0667	Aldo Keto reductase
B737_RS40995	COG0477	Major facilitator Superfamily
B737_RS41025	COG2207	Transcriptional regulator
B737_RS41040	COG5297	Belongs to the glycosyl hydrolase family 6
B737_RS41055	COG2205	protein histidine kinase activity
B737_RS41060	COG0148	phosphopyruvate hydratase activity
B737_RS41070	COG1132	(ABC) transporter
B737_RS41170	COG2815	serine threonine protein kinase
B737_RS41170	COG0515	serine threonine protein kinase
B737_RS41205	COG1191	sigma factor activity
B737_RS41275	COG1515	deoxyribonuclease V activity
B737_RS41290	COG4608	Belongs to the ABC transporter superfamily
B737_RS41295	COG0444	Belongs to the ABC transporter superfamily
B737_RS41300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS41305	COG0601	transmembrane transport
B737_RS41335	COG0148	phosphopyruvate hydratase activity
B737_RS41355	COG0672	)-iron permease
B737_RS41360	COG2822	iron ion transport
B737_RS41365	COG2837	iron assimilation
B737_RS41395	COG1131	(ABC) transporter
B737_RS41445	COG0586	Pfam SNARE associated Golgi protein
B737_RS41455	COG4585	Histidine kinase
B737_RS41460	COG2197	response regulator
B737_RS41465	COG2133	pyrroloquinoline quinone binding
B737_RS41485	COG1051	belongs to the nudix hydrolase family
B737_RS41510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B737_RS41540	COG0193	aminoacyl-tRNA hydrolase activity
B737_RS41545	COG3599	regulation of cell shape
B737_RS41555	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS41560	COG0488	(ABC) transporter
B737_RS41570	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B737_RS41575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B737_RS41580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B737_RS41585	COG3583	domain protein
B737_RS41590	COG0084	hydrolase, TatD family'
B737_RS41595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B737_RS41650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B737_RS41655	COG0515	serine threonine protein kinase
B737_RS41655	COG2815	serine threonine protein kinase
B737_RS41675	COG2258	MOSC domain
B737_RS41690	COG1595	DNA-templated transcription, initiation
B737_RS41735	COG5001	Diguanylate cyclase
B737_RS41745	COG2124	cytochrome p450
B737_RS41750	COG1192	Involved in chromosome partitioning
B737_RS41765	COG0702	epimerase
B737_RS41775	COG0745	RESPONSE REGULATOR receiver
B737_RS41780	COG2205	protein histidine kinase activity
B737_RS41785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B737_RS41790	COG1181	Belongs to the D-alanine--D-alanine ligase family
B737_RS41800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B737_RS41805	COG1733	regulation of RNA biosynthetic process
B737_RS41810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B737_RS41815	COG2226	methyltransferase
B737_RS41815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B737_RS41815	COG3433	isochorismatase activity
B737_RS41830	COG1280	lysine exporter protein (LysE YggA)
B737_RS41840	COG0515	serine threonine protein kinase
B737_RS41895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B737_RS41905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B737_RS41910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B737_RS41935	COG0521	Mo-molybdopterin cofactor biosynthetic process
B737_RS41935	COG0315	cyclic pyranopterin monophosphate synthase activity
B737_RS41955	COG5002	protein histidine kinase activity
B737_RS41960	COG0745	RESPONSE REGULATOR receiver
B737_RS41980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B737_RS41995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS42005	COG1349	DNA-binding transcription factor activity
B737_RS42010	COG2205	protein histidine kinase activity
B737_RS42015	COG0745	RESPONSE REGULATOR receiver
B737_RS42020	COG2860	membrane
B737_RS42025	COG2197	response regulator
B737_RS42030	COG2264	protein methyltransferase activity
B737_RS42040	COG0477	Major facilitator Superfamily
B737_RS42050	COG0667	Aldo Keto reductase
B737_RS42055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B737_RS42070	COG2815	serine threonine protein kinase
B737_RS42070	COG0515	serine threonine protein kinase
B737_RS42075	COG0483	inositol monophosphate 1-phosphatase activity
B737_RS42085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B737_RS42100	COG0297	glycogen (starch) synthase activity
B737_RS42120	COG3285	dna ligase
B737_RS42120	COG1793	dna ligase
B737_RS42130	COG0583	DNA-binding transcription factor activity
B737_RS42140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B737_RS42140	COG2755	lipolytic protein G-D-S-L family
B737_RS42185	COG1960	acyl-CoA dehydrogenase activity
B737_RS42200	COG0444	Belongs to the ABC transporter superfamily
B737_RS42205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS42210	COG0601	transmembrane transport
B737_RS42220	COG0747	negative chemotaxis
B737_RS42250	COG3469	chitinase activity
B737_RS42260	COG2814	Major facilitator Superfamily
B737_RS42265	COG4336	lyase activity
B737_RS42270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B737_RS42275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B737_RS42280	COG1984	allophanate hydrolase subunit 2
B737_RS42320	COG1321	iron dependent repressor
B737_RS42340	COG1024	Enoyl-CoA hydratase
B737_RS42345	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS42370	COG1169	isochorismate synthase
B737_RS42385	COG2182	Extracellular solute-binding protein
B737_RS42390	COG1175	transmembrane transport
B737_RS42395	COG0395	ABC-type sugar transport system, permease component
B737_RS42420	COG1595	DNA-templated transcription, initiation
B737_RS42435	COG0277	FAD linked oxidase domain protein
B737_RS42460	COG4152	abc transporter atp-binding protein
B737_RS42475	COG0415	Belongs to the DNA photolyase family
B737_RS42495	COG1960	acyl-CoA dehydrogenase activity
B737_RS42520	COG2017	converts alpha-aldose to the beta-anomer
B737_RS42530	COG1309	transcriptional regulator
B737_RS42555	COG0259	pyridoxamine-phosphate oxidase activity
B737_RS42575	COG0829	nickel cation binding
B737_RS42580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B737_RS42590	COG0804	urea catabolic process
B737_RS42595	COG0832	Belongs to the urease beta subunit family
B737_RS42600	COG0831	urea catabolic process
B737_RS42635	COG2197	response regulator
B737_RS42640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B737_RS42655	COG5650	phosphatidylinositol metabolic process
B737_RS42660	COG1228	amidohydrolase
B737_RS42665	COG1136	(ABC) transporter
B737_RS42665	COG0577	efflux transmembrane transporter activity
B737_RS42670	COG1136	(ABC) transporter
B737_RS42670	COG0577	efflux transmembrane transporter activity
B737_RS42685	COG0745	RESPONSE REGULATOR receiver
B737_RS42690	COG2205	protein histidine kinase activity
B737_RS42715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B737_RS42740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B737_RS42745	COG2814	Major facilitator Superfamily
B737_RS42760	COG2252	PERMEase
B737_RS42785	COG2814	Major facilitator Superfamily
B737_RS42795	COG1278	Cold shock
B737_RS42815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B737_RS42820	COG0318	PFAM AMP-dependent synthetase and ligase
B737_RS42830	COG1595	DNA-templated transcription, initiation
B737_RS42840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B737_RS42880	COG0384	phenazine biosynthesis protein PhzF
B737_RS42885	COG3304	Inner membrane component domain
B737_RS42890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B737_RS42925	COG1846	Transcriptional regulator
B737_RS42940	COG1388	LysM domain
B737_RS42985	COG2018	Roadblock/LC7 domain
B737_RS43000	COG2018	Roadblock/LC7 domain
B737_RS43005	COG0642	Histidine kinase
B737_RS43010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B737_RS43015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS43020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS43025	COG1116	anion transmembrane transporter activity
B737_RS43060	COG3142	Participates in the control of copper homeostasis
B737_RS43080	COG1061	Type III restriction enzyme res subunit
B737_RS43100	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS43115	COG0459	protein refolding
B737_RS43125	COG1278	Cold shock
B737_RS43155	COG2261	transglycosylase associated protein
B737_RS43165	COG0688	phosphatidylethanolamine metabolic process
B737_RS43175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B737_RS43190	COG0242	peptide deformylase activity
B737_RS43200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B737_RS43205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B737_RS43210	COG0351	phosphomethylpyrimidine kinase
B737_RS43230	COG2022	thiamine diphosphate biosynthetic process
B737_RS43240	COG2022	thiamine diphosphate biosynthetic process
B737_RS43240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B737_RS43245	COG0352	thiamine-phosphate diphosphorylase activity
B737_RS43255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B737_RS43260	COG0477	Major facilitator Superfamily
B737_RS43270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B737_RS43275	COG2971	BadF BadG BcrA BcrD
B737_RS43285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B737_RS43315	COG3903	Transcriptional regulator
B737_RS43315	COG3629	intracellular signal transduction
B737_RS43320	COG5285	phytanoyl-CoA dioxygenase
B737_RS43325	COG1917	Cupin 2, conserved barrel domain protein
B737_RS43340	COG1752	Esterase of the alpha-beta hydrolase superfamily
B737_RS43350	COG1733	regulation of RNA biosynthetic process
B737_RS43355	COG4399	Belongs to the UPF0754 family
B737_RS43370	COG5416	Lipopolysaccharide assembly protein A domain
B737_RS43465	COG3971	2-oxopent-4-enoate hydratase activity
B737_RS43470	COG0346	lactoylglutathione lyase activity
B737_RS43480	COG1832	CoA-binding protein
B737_RS43525	COG0745	RESPONSE REGULATOR receiver
B737_RS43530	COG2205	protein histidine kinase activity
B737_RS43535	COG1492	cobalamin metabolic process
B737_RS43540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B737_RS43560	COG1620	l-lactate permease
B737_RS43570	COG4941	Belongs to the sigma-70 factor family
B737_RS43575	COG3795	YCII-related domain
B737_RS43580	COG3795	YCII-related domain
B737_RS43600	COG0642	Histidine kinase
B737_RS43640	COG1595	DNA-templated transcription, initiation
B737_RS43680	COG0789	Transcriptional regulator
B737_RS43710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B737_RS43745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B737_RS43755	COG1329	Transcriptional regulator
B737_RS43760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B737_RS43765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B737_RS43785	COG0215	cysteine-tRNA ligase activity
B737_RS43825	COG0235	Class ii aldolase
B737_RS43840	COG4399	Belongs to the UPF0754 family
B737_RS43845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B737_RS43850	COG1121	(ABC) transporter
B737_RS43855	COG0803	Belongs to the bacterial solute-binding protein 9 family
B737_RS43860	COG1609	Transcriptional regulator
B737_RS43895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B737_RS43905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B737_RS43980	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B737_RS43995	COG1396	sequence-specific DNA binding
B737_RS44030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B737_RS44040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B737_RS44045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B737_RS44050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B737_RS44075	COG0789	Transcriptional regulator
B737_RS44090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B737_RS44095	COG0302	gtp cyclohydrolase
B737_RS44100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B737_RS44130	COG0037	tRNA processing
B737_RS44140	COG2027	D-alanyl-D-alanine carboxypeptidase
B737_RS44145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B737_RS44155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B737_RS44160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B737_RS44245	COG2188	Transcriptional regulator
B737_RS44260	COG1674	ftsk spoiiie
B737_RS44305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B737_RS44310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B737_RS44340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B737_RS44340	COG1754	DNA topoisomerase type I activity
B737_RS44360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B737_RS44365	COG1205	dead DEAH box helicase
B737_RS44365	COG1111	helicase
B737_RS44410	COG1472	Belongs to the glycosyl hydrolase 3 family
B737_RS44415	COG3876	Protein conserved in bacteria
B737_RS44420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B737_RS44425	COG1737	Transcriptional regulator
B737_RS44430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B737_RS44435	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
B737_RS44445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B737_RS44455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B737_RS44475	COG3104	oligopeptide transport
B737_RS44480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B737_RS44490	COG0596	Alpha beta hydrolase
B737_RS44575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B737_RS44625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B737_RS44635	COG1408	metallophosphoesterase
B737_RS44645	COG2226	methyltransferase
B737_RS44680	COG0463	Glycosyl transferase, family 2
B737_RS44685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B737_RS44695	COG2192	nodulation
B737_RS44710	COG0076	glutamate decarboxylase activity
B737_RS44715	COG0783	Belongs to the Dps family
B737_RS44720	COG1764	response to oxidative stress
B737_RS44730	COG0657	acetylesterase activity
B737_RS44745	COG2814	Major facilitator Superfamily
B737_RS44760	COG1690	Belongs to the RtcB family
B737_RS44825	COG0583	DNA-binding transcription factor activity
B737_RS44830	COG0697	spore germination
B737_RS44845	COG3795	YCII-related domain
B737_RS44850	COG4941	Belongs to the sigma-70 factor family
B737_RS44855	COG4608	Belongs to the ABC transporter superfamily
B737_RS44865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B737_RS44870	COG0601	transmembrane transport
B737_RS44875	COG0747	negative chemotaxis
B737_RS44885	COG1216	Glycosyl transferase, family 2
B737_RS44905	COG1215	transferase activity, transferring glycosyl groups
B737_RS44915	COG1705	Flagellar rod assembly protein muramidase FlgJ
B737_RS44920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B737_RS44925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B737_RS44935	COG1733	regulation of RNA biosynthetic process
B737_RS44940	COG3467	pyridoxamine 5'-phosphate
B737_RS44945	COG2801	Transposase and inactivated derivatives
B737_RS44990	COG1116	anion transmembrane transporter activity
B737_RS44995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B737_RS45005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B737_RS45010	COG2205	protein histidine kinase activity
B737_RS45015	COG0745	RESPONSE REGULATOR receiver
B737_RS45030	COG2197	response regulator
B737_RS45050	COG1250	3-hydroxyacyl-CoA dehydrogenase
B737_RS45055	COG5479	isomerase activity
B737_RS45055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B737_RS45100	COG1674	ftsk spoiiie
B737_RS45140	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
B737_RS45145	COG2175	clavaminate synthase activity
B737_RS45160	COG0702	epimerase
B737_RS45185	COG1473	amidohydrolase
B737_RS45200	COG4702	Belongs to the UPF0303 family
B737_RS45210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B737_RS45215	COG0789	Transcriptional regulator
B737_RS45220	COG0395	ABC-type sugar transport system, permease component
B737_RS45225	COG1175	transmembrane transport
B737_RS45240	COG1802	Transcriptional regulator
B737_RS45270	COG3973	AAA domain
B737_RS45300	COG0673	inositol 2-dehydrogenase activity
B737_RS45315	COG3345	alpha-galactosidase
B737_RS45330	COG2188	Transcriptional regulator
B737_RS45335	COG1397	ADP-ribosylglycohydrolase
B737_RS45340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS45355	COG0596	Alpha beta hydrolase
B737_RS45360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B737_RS45375	COG1316	TRANSCRIPTIONal
B737_RS45385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B737_RS45390	COG0581	inorganic phosphate transmembrane transporter activity
B737_RS45400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B737_RS45410	COG0745	RESPONSE REGULATOR receiver
B737_RS45440	COG4044	May play a role in the intracellular transport of hydrophobic ligands
B737_RS45445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B737_RS45450	COG1984	allophanate hydrolase subunit 2
B737_RS45500	COG3845	ABC transporter
B737_RS45535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B737_RS45600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B737_RS45610	COG1132	(ABC) transporter
B737_RS45615	COG0047	phosphoribosylformylglycinamidine synthase activity
B737_RS45620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B737_RS45665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B737_RS45675	COG1126	abc transporter atp-binding protein
B737_RS45680	COG0765	amino acid transport
B737_RS45690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B737_RS45700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B737_RS45705	COG4948	Mandelate Racemase Muconate Lactonizing
B737_RS45720	COG2186	Transcriptional regulator
B737_RS45745	COG0546	phosphoglycolate phosphatase activity
B737_RS45760	COG0436	Aminotransferase
B737_RS45765	COG3953	SLT domain
B737_RS45765	COG5280	Phage tail tape measure protein TP901
B737_RS45800	COG0584	glycerophosphoryl diester phosphodiesterase
B737_RS45825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS45835	COG2814	Major facilitator Superfamily
B737_RS45840	COG0025	NhaP-type Na H and K H
B737_RS45845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B737_RS45855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B737_RS45925	COG0667	Aldo Keto reductase
B737_RS45930	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS45980	COG0586	Pfam SNARE associated Golgi protein
B737_RS45995	COG0277	FAD linked oxidase domain protein
B737_RS46000	COG3467	pyridoxamine 5'-phosphate
B737_RS46020	COG0586	Pfam SNARE associated Golgi protein
B737_RS46035	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS46040	COG0572	uridine kinase
B737_RS46045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS46080	COG0243	molybdopterin cofactor binding
B737_RS46125	COG1136	(ABC) transporter
B737_RS46130	COG4221	oxidoreductase activity
B737_RS46145	COG0542	response to heat
B737_RS46170	COG0412	Dienelactone hydrolase
B737_RS46185	COG0789	Transcriptional regulator
B737_RS46190	COG0484	heat shock protein binding
B737_RS46195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B737_RS46200	COG0443	Heat shock 70 kDa protein
B737_RS46235	COG2181	nitrate reductase activity
B737_RS46235	COG0247	lactate metabolic process
B737_RS46250	COG2340	Cysteine-rich secretory protein family
B737_RS46290	COG4941	Belongs to the sigma-70 factor family
B737_RS46295	COG3795	YCII-related domain
B737_RS46300	COG2124	cytochrome p450
B737_RS46345	COG3663	DNA glycosylase
B737_RS46350	COG2197	response regulator
B737_RS46355	COG1960	acyl-CoA dehydrogenase activity
B737_RS46365	COG0477	Major facilitator Superfamily
B737_RS46385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B737_RS46410	COG1126	abc transporter atp-binding protein
B737_RS46435	COG1305	Transglutaminase-like
B737_RS46450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B737_RS46460	COG0022	dehydrogenase e1 component
B737_RS46465	COG0508	dehydrogenase complex catalyzes the overall conversion of
B737_RS46490	COG3030	protein affecting phage T7 exclusion by the F plasmid
B737_RS46530	COG1309	transcriptional regulator
B737_RS46535	COG2030	dehydratase
B737_RS46540	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS46545	COG0183	Belongs to the thiolase family
B737_RS46620	COG1131	(ABC) transporter
B737_RS46635	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B737_RS46650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B737_RS46665	COG4585	Histidine kinase
B737_RS46670	COG2197	response regulator
B737_RS46675	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS46695	COG1131	(ABC) transporter
B737_RS46710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B737_RS46720	COG1136	(ABC) transporter
B737_RS46730	COG2197	response regulator
B737_RS46745	COG0402	S-adenosylhomocysteine deaminase activity
B737_RS46750	COG4221	oxidoreductase activity
B737_RS46765	COG2814	Major facilitator Superfamily
B737_RS46770	COG1846	Transcriptional regulator
B737_RS46775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B737_RS46785	COG1595	DNA-templated transcription, initiation
B737_RS46795	COG1695	Transcriptional regulator
B737_RS46805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B737_RS46810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B737_RS46815	COG0673	inositol 2-dehydrogenase activity
B737_RS46820	COG1940	carbohydrate kinase activity
B737_RS46850	COG0360	Binds together with S18 to 16S ribosomal RNA
B737_RS46860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B737_RS46865	COG0359	binds to the 23S rRNA
B737_RS46905	COG3384	dioxygenase
B737_RS46930	COG2197	response regulator
B737_RS46945	COG0477	Major facilitator Superfamily
B737_RS46950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B737_RS46960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B737_RS47015	COG1028	Short-chain dehydrogenase reductase Sdr
B737_RS47020	COG0495	leucyl-tRNA aminoacylation
B737_RS47100	COG0617	tRNA 3'-terminal CCA addition
B737_RS47130	COG1595	DNA-templated transcription, initiation
B737_RS47145	COG0492	ferredoxin-NADP+ reductase activity
B737_RS47145	COG3118	belongs to the thioredoxin family
B737_RS47150	COG3409	Peptidoglycan-binding domain 1 protein
B737_RS47150	COG0860	N-Acetylmuramoyl-L-alanine amidase
B737_RS47165	COG1181	Belongs to the D-alanine--D-alanine ligase family
B737_RS47175	COG1192	Involved in chromosome partitioning
B737_RS47180	COG0357	Ribosomal RNA small subunit methyltransferase G
B737_RS47195	COG0706	membrane insertase activity
B737_RS47200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B737_RS47225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B737_RS47235	COG0535	radical SAM domain protein